{"meta":{"query_hash":"fdb2552b09cf","filters":{"venue":"Journal of Clinical Investigation"},"cohort_total":991,"direct_labels_cover":0,"predictions_cover":991,"exported":991,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/fdb2552b09cf","api":"https://metacan.xera.ac/api/v1/cohort?venue=Journal+of+Clinical+Investigation"},"results":[{"id":"W1518189766","doi":"10.1172/jci40271","title":"Tapping the riches of science","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Biotechnology and Related Fields","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Political science; State (computer science); Management; Library science; Engineering; Mathematics; Economics; Computer science","score_opus":0.08531633496964794,"score_gpt":0.4055372690247445,"score_spread":0.32022093405509655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1518189766","genre_codex":"other","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012603566,0.1178112,0.011514609,0.23201545,0.011060047,0.00007021114,0.00015316976,0.00026529966,0.61450636],"genre_scores_gemma":[0.5963776,0.10531903,0.0129936505,0.100808345,0.016599625,0.00033415022,0.00020727112,0.00041137057,0.16694896],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9944543,0.0025905855,0.00015667146,0.00060351705,0.0015166702,0.0006781171],"domain_scores_gemma":[0.98692536,0.009823391,0.00040461667,0.001193571,0.000930511,0.0007225738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0058951555,0.0007752868,0.00083253783,0.0033269867,0.007542068,0.01648369,0.00089275214,0.0031251204,0.0077666994],"category_scores_gemma":[0.01084344,0.0005651876,0.0006162123,0.001682897,0.039378185,0.021406595,0.008624847,0.0093647605,0.0015719233],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021444524,0.000011792098,0.00023563088,0.00018517896,0.000013541451,0.00008801205,0.0075782984,0.00020900481,0.0002724611,0.92156905,0.049637824,0.02017781],"study_design_scores_gemma":[0.0000064239434,0.000025660363,0.00033790324,0.00046357382,0.000009231381,0.00013572985,0.0040605413,0.00019897107,0.00025351558,0.45246613,0.5420237,0.000018626679],"about_ca_topic_score_codex":0.0022755458,"about_ca_topic_score_gemma":0.0050367177,"teacher_disagreement_score":0.01648369,"about_ca_system_score_codex":0.0069301534,"about_ca_system_score_gemma":0.007570757,"threshold_uncertainty_score":0.05028206},"labels":[],"label_agreement":null},{"id":"W1596081492","doi":"10.1172/jci77030","title":"S6K1 controls pancreatic β cell size independently of intrauterine growth restriction","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Instituto de Salud Carlos III; Ministerio de Ciencia e Innovación; Université de Lausanne; Sungkyunkwan University; European Commission","keywords":"P70-S6 Kinase 1; Intrauterine growth restriction; Endocrinology; Biology; Internal medicine; Insulin resistance; Insulin; Cell growth; Fetus; Pregnancy; Cell biology; Medicine; Protein kinase B; Signal transduction; Genetics","score_opus":0.083542276970126,"score_gpt":0.35210249250045367,"score_spread":0.26856021553032766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1596081492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99288756,0.0031939773,0.0015025875,0.00022195348,0.00005965758,0.000024734585,0.00034924728,0.0001402977,0.0016200066],"genre_scores_gemma":[0.9946241,0.0022202353,0.0009344206,0.00006612153,0.0000151539925,0.00004457142,0.00022723437,0.00004075176,0.0018273445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998778,0.000027431783,0.000012413849,0.00003246675,0.000020448988,0.00002939388],"domain_scores_gemma":[0.9997559,0.00003146627,0.00008282213,0.000024996252,0.000013764541,0.00009108941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016069178,0.00046984234,0.0002886125,0.00034592763,0.00014096493,0.00041567424,0.00033282628,0.00029367788,0.0011485892],"category_scores_gemma":[0.00023640187,0.0001989032,0.00015917122,0.00016633289,0.00050629367,0.00017322903,0.0002404862,0.0006053388,0.00029762826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018885412,0.00011894851,0.0010959664,0.000099801204,0.000010500618,0.000119936325,0.000030918593,0.000102530925,0.9915848,0.00020235887,0.00014879061,0.004596805],"study_design_scores_gemma":[0.00030492494,0.0017252042,0.049781874,0.00003882872,0.00006574671,0.0010677053,0.00015857391,0.0022304114,0.9378884,0.00033038043,0.006386078,0.000021833823],"about_ca_topic_score_codex":0.0003199543,"about_ca_topic_score_gemma":0.00045979608,"teacher_disagreement_score":0.0011485892,"about_ca_system_score_codex":0.00022963037,"about_ca_system_score_gemma":0.00023371674,"threshold_uncertainty_score":0.0038424134},"labels":[],"label_agreement":null},{"id":"W1598254642","doi":"10.1172/jci29103","title":"Islet   cell failure in type 2 diabetes","year":2006,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1659,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; ACT Government","keywords":"Beta cell; Type 2 diabetes; Islet; Context (archaeology); Insulin resistance; Diabetes mellitus; BETA (programming language); Bioinformatics; Pathogenesis; Cell; Medicine; Biology; Cell type; Internal medicine; Endocrinology; Genetics; Computer science","score_opus":0.12311902243374906,"score_gpt":0.4066883381839086,"score_spread":0.28356931575015953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1598254642","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000923651,0.9983594,0.00010646326,0.00014768362,0.0003621947,0.0000029054531,0.000007055334,0.000007854673,0.0009141512],"genre_scores_gemma":[0.00056650833,0.99832314,0.00013300953,0.00016226525,0.00029810076,0.0000033839663,0.000012924662,0.0000011303625,0.0004995463],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999824,0.000031797295,0.00002742382,0.000031820713,0.000069699905,0.000015288697],"domain_scores_gemma":[0.9997563,0.00009277774,0.000043719905,0.000010924724,0.00006592977,0.000030429661],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004426472,0.0010318668,0.001853032,0.0020972285,0.0003087131,0.0007232598,0.00076882396,0.0010802061,0.0032723616],"category_scores_gemma":[0.0006192346,0.0002170058,0.00032975135,0.0023708143,0.00048199968,0.0010727936,0.0006531818,0.0014370647,0.0035901398],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007269141,0.000056089935,0.0002925639,0.010715197,0.000055569646,0.0008364779,0.000058526504,0.00025122426,0.001340454,0.0020024837,0.043418158,0.9409006],"study_design_scores_gemma":[0.000025462923,0.000105182065,0.0017191309,0.0044062645,0.00008868831,0.009164708,0.000103108316,0.00006195459,0.00038862828,0.0027863726,0.9811288,0.000021638458],"about_ca_topic_score_codex":0.0007366791,"about_ca_topic_score_gemma":0.001143162,"teacher_disagreement_score":0.0032723616,"about_ca_system_score_codex":0.00038741904,"about_ca_system_score_gemma":0.0006778086,"threshold_uncertainty_score":0.010947108},"labels":[],"label_agreement":null},{"id":"W1921456558","doi":"10.1172/jci81261","title":"Inflammatory IL-15 is required for optimal memory T cell responses","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":111,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Holden Comprehensive Cancer Center, University of Iowa; National Center for Research Resources; American Heart Association; Roy J. and Lucille A. Carver College of Medicine, University of Iowa; National Cancer Institute; National Institutes of Health; McGill University","keywords":"Cytotoxic T cell; CD8; Biology; Memory T cell; T cell; Immunology; mTORC1; CD28; Antigen; Memory cell; Cell biology; Immune system; PI3K/AKT/mTOR pathway; Signal transduction; In vitro","score_opus":0.11659476115790512,"score_gpt":0.36437240718899455,"score_spread":0.24777764603108943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1921456558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98954445,0.0059175463,0.0019051977,0.00023069969,0.00007718185,0.00005823214,0.00025678135,0.000117419644,0.00189247],"genre_scores_gemma":[0.99733776,0.00062697066,0.0011669502,0.0000626719,0.000023927745,0.000032583812,0.00018212864,0.000009067374,0.0005579305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997292,0.000059821352,0.0000409332,0.00004203342,0.000041435145,0.00008657513],"domain_scores_gemma":[0.9998228,0.00002154732,0.000052526804,0.00001688279,0.000016299537,0.00006989684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021792205,0.00031903718,0.00039161055,0.00019102379,0.00018250717,0.0005446676,0.00015103818,0.00031663215,0.0015934281],"category_scores_gemma":[0.00035222835,0.00014700291,0.00020939657,0.00010399642,0.0002583737,0.00025081873,0.00025297928,0.0006194117,0.0004470541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006413526,0.00008001535,0.0019133232,0.00013339001,0.000010624485,0.00017260255,0.000033075343,0.00013763188,0.99036354,0.00020079498,0.000121601224,0.0061921505],"study_design_scores_gemma":[0.00019524789,0.0025537517,0.047067054,0.00010736684,0.000079052064,0.0019623558,0.00014788516,0.0016758936,0.9343633,0.00058030844,0.011253719,0.000014032546],"about_ca_topic_score_codex":0.00022434621,"about_ca_topic_score_gemma":0.00045692158,"teacher_disagreement_score":0.0015934281,"about_ca_system_score_codex":0.00033580378,"about_ca_system_score_gemma":0.0004399656,"threshold_uncertainty_score":0.0053305626},"labels":[],"label_agreement":null},{"id":"W1963853457","doi":"10.1172/jci75247","title":"Proteasome function is required for platelet production","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Volkswagen Foundation; National Institute of General Medical Sciences; American Heart Association","keywords":"Platelet; Function (biology); Production (economics); Proteasome; Chemistry; Computational biology; Biology; Cell biology; Medicine; Internal medicine","score_opus":0.07441451484805864,"score_gpt":0.3446982882155616,"score_spread":0.270283773367503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963853457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9446253,0.033778653,0.009218872,0.001005133,0.0002480176,0.000055896828,0.0018858571,0.00060049666,0.008581889],"genre_scores_gemma":[0.98941445,0.004267421,0.001646533,0.00008423887,0.00006052293,0.000026475966,0.0011333829,0.000034122,0.0033328165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997794,0.0000252202,0.000028182107,0.000051151357,0.00006318254,0.000052904885],"domain_scores_gemma":[0.9997602,0.00002062716,0.00008730246,0.000025077732,0.000040272178,0.00006646551],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013992023,0.00028249103,0.00027178536,0.000246397,0.00025063966,0.00069563044,0.00012086832,0.00029644594,0.001499111],"category_scores_gemma":[0.00022663308,0.00016500785,0.00027267198,0.00012261272,0.00013042336,0.00016417073,0.00021104558,0.00044164364,0.0010489273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013500953,0.000020106476,0.00085223216,0.00007624003,0.000014230416,0.00028367346,0.000015549425,0.00005762137,0.99339175,0.0004304724,0.00038199913,0.0043410854],"study_design_scores_gemma":[0.000047242618,0.000332294,0.03804968,0.000030251542,0.00004819512,0.0029637667,0.000043188935,0.0009571066,0.9321795,0.00042374857,0.024911804,0.000013188146],"about_ca_topic_score_codex":0.0004078252,"about_ca_topic_score_gemma":0.00047152754,"teacher_disagreement_score":0.001499111,"about_ca_system_score_codex":0.00036084827,"about_ca_system_score_gemma":0.00034512402,"threshold_uncertainty_score":0.0050150156},"labels":[],"label_agreement":null},{"id":"W1964631459","doi":"10.1172/jci120018","title":"The good, the bad, the mad cow","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Biology","score_opus":0.0410962044553091,"score_gpt":0.36168449284146836,"score_spread":0.32058828838615927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964631459","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009080796,0.061589867,0.00035044792,0.8462849,0.028728565,0.000020459067,0.00039456555,0.00013539684,0.053415],"genre_scores_gemma":[0.17419271,0.053562842,0.0010833653,0.6075244,0.013431533,0.000020809553,0.00041997424,0.00016152082,0.14960296],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99787617,0.00029645313,0.00004484831,0.0003269046,0.0008286149,0.0006269931],"domain_scores_gemma":[0.99711823,0.00030866588,0.000101601385,0.000096755764,0.0009761517,0.0013985727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016244503,0.000809504,0.0005021895,0.0010234704,0.013896216,0.0067308047,0.00097199326,0.0041042967,0.011894739],"category_scores_gemma":[0.005272088,0.00034963054,0.00034503717,0.00077779504,0.0076709003,0.003141593,0.0020911798,0.009259475,0.0021182478],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011655265,0.000023967827,0.003768603,0.00011219645,0.000027715989,0.0011476411,0.0033261706,0.000023935572,0.0009282202,0.009765113,0.9411883,0.039571542],"study_design_scores_gemma":[0.000011922882,0.000020898444,0.0044961143,0.00020444172,0.00001668898,0.0012490246,0.0041190353,0.000031306143,0.00020212775,0.0029069735,0.98671025,0.000031249616],"about_ca_topic_score_codex":0.70792836,"about_ca_topic_score_gemma":0.838892,"teacher_disagreement_score":0.70792836,"about_ca_system_score_codex":0.022994857,"about_ca_system_score_gemma":0.023740234,"threshold_uncertainty_score":0.5875834},"labels":[],"label_agreement":null},{"id":"W1964768186","doi":"10.1172/jci75181","title":"Netrin-1 controls sympathetic arterial innervation","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Fondation de France; Killam Trusts; Institut National de la Santé et de la Recherche Médicale; Fondation Leducq; Agence Nationale de la Recherche","keywords":"Netrin; Sympathetic nervous system; Vasoconstriction; Biology; Artery; Sympathetic innervation; Medicine; Anatomy; Endocrinology; Internal medicine; Axon guidance; Axon; Blood pressure","score_opus":0.13700394126108983,"score_gpt":0.3699917334903225,"score_spread":0.23298779222923266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964768186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99416536,0.0017220116,0.0010657208,0.00010379171,0.000017084923,0.000014640377,0.00010465666,0.000042189808,0.0027647126],"genre_scores_gemma":[0.9970763,0.00067561737,0.000690262,0.000030156001,0.0000064949536,0.00001036399,0.00008389851,0.000009651112,0.0014173214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998629,0.000026372974,0.000010020328,0.000029687526,0.00003286053,0.000038045197],"domain_scores_gemma":[0.99983823,0.000015559803,0.000057553083,0.000008489494,0.000014533378,0.00006561878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014610437,0.00018002217,0.00022321728,0.00024125396,0.00018876001,0.00046747882,0.00018199366,0.00024133768,0.0006181146],"category_scores_gemma":[0.00023197244,0.00011366712,0.00008941071,0.00007572012,0.0002583998,0.0001851191,0.00025335653,0.00044731778,0.00026748257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019230577,0.000024030074,0.0018290709,0.00003475723,0.000004614324,0.00013494164,0.000021010697,0.00012635533,0.99402255,0.00033404335,0.00007821145,0.0031980358],"study_design_scores_gemma":[0.000041355575,0.0002922996,0.07496412,0.000032802367,0.000048527418,0.0010151954,0.000098141725,0.0045069656,0.91405874,0.0004009618,0.0045262347,0.000014646794],"about_ca_topic_score_codex":0.00045733576,"about_ca_topic_score_gemma":0.0011587291,"teacher_disagreement_score":0.0006181146,"about_ca_system_score_codex":0.00053843245,"about_ca_system_score_gemma":0.00030107098,"threshold_uncertainty_score":0.003906667},"labels":[],"label_agreement":null},{"id":"W1964899619","doi":"10.1172/jci61345","title":"Plasmacytoid dendritic cells lead the charge against tumors","year":2012,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; York University; NYU Langone Medical Center; Melanoma Research Alliance","keywords":"Imiquimod; TLR7; Immune system; Cancer research; Immunology; Melanoma; Agonist; Plasmacytoid dendritic cell; Dendritic cell; Medicine; Biology; Receptor; Innate immune system; Toll-like receptor; Internal medicine","score_opus":0.0636077687916409,"score_gpt":0.32194436345662103,"score_spread":0.25833659466498016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964899619","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017223066,0.0132904295,0.002064724,0.8929273,0.056319945,0.00009696164,0.0001297036,0.0004257054,0.017522179],"genre_scores_gemma":[0.20755695,0.013563429,0.0025896288,0.5968124,0.12014154,0.00021254181,0.00012888391,0.0000822608,0.05891238],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99956673,0.00012460607,0.000040319173,0.000057647965,0.00014754923,0.00006326495],"domain_scores_gemma":[0.9992023,0.00034104925,0.000060088783,0.00007324031,0.00022555882,0.0000978169],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056016294,0.00050236954,0.00047215878,0.00023259214,0.0006603364,0.0009440783,0.00050032727,0.006748252,0.0029035732],"category_scores_gemma":[0.003249185,0.00020081682,0.00040475128,0.000105780215,0.0008817902,0.0007889351,0.00038713645,0.007316438,0.0037534481],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00083989714,0.00026392442,0.0019103377,0.00025419155,0.00004090567,0.010853479,0.00013336293,0.00017062569,0.013866685,0.00825536,0.89441526,0.06899586],"study_design_scores_gemma":[0.00078914,0.0004685271,0.0022706944,0.00015357921,0.000054877037,0.017443847,0.00023618543,0.0016465044,0.013233311,0.0150077725,0.94865716,0.000038469683],"about_ca_topic_score_codex":0.00034524364,"about_ca_topic_score_gemma":0.00041497228,"teacher_disagreement_score":0.006748252,"about_ca_system_score_codex":0.00095493183,"about_ca_system_score_gemma":0.00035250952,"threshold_uncertainty_score":0.009713471},"labels":[],"label_agreement":null},{"id":"W1965772617","doi":"10.1172/jci10373","title":"NF-κB: pivotal mediator or innocent bystander in atherogenesis?","year":2001,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":728,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Bystander effect; Mediator; Cancer research; Cell biology; NFKB1; NF-κB; Medicine; Inflammation; Immunology; Biology; Genetics; Transcription factor; Gene","score_opus":0.21664456780240926,"score_gpt":0.45101289171729597,"score_spread":0.2343683239148867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965772617","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009454648,0.9416016,0.0055282726,0.028751059,0.0076434575,0.000035145164,0.00022897145,0.00015099114,0.006605881],"genre_scores_gemma":[0.14124572,0.81079644,0.0028037238,0.009609387,0.023577187,0.00007954864,0.00030301622,0.000054187378,0.011530704],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99916434,0.00015599885,0.00006166389,0.00017971049,0.0002424837,0.00019581705],"domain_scores_gemma":[0.99940264,0.00013124637,0.00014440255,0.00004744077,0.00008371881,0.0001905325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019926785,0.0010194334,0.0013305969,0.0005862863,0.00059129624,0.0029195342,0.0014321384,0.0027913635,0.0048434054],"category_scores_gemma":[0.0012293713,0.00023692241,0.00028277017,0.0004786042,0.0030013795,0.0045794556,0.0013752229,0.0024447888,0.0023129873],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002395138,0.00037712837,0.0064483997,0.012998644,0.00022105397,0.0035659617,0.002442961,0.0004927898,0.07272471,0.15508465,0.12921351,0.6140351],"study_design_scores_gemma":[0.00015868102,0.000889043,0.0035538932,0.0028192196,0.0001187913,0.0049205003,0.0012105712,0.00057719526,0.011192776,0.10048876,0.87398314,0.00008743764],"about_ca_topic_score_codex":0.0002979207,"about_ca_topic_score_gemma":0.0002963716,"teacher_disagreement_score":0.0048434054,"about_ca_system_score_codex":0.0007201078,"about_ca_system_score_gemma":0.0010614895,"threshold_uncertainty_score":0.016202807},"labels":[],"label_agreement":null},{"id":"W1966555773","doi":"10.1172/jci77888","title":"Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":202,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Key Research and Development Program of China; Canadian Institutes of Health Research; National Institutes of Health; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China; Fondation Brain Canada","keywords":"Long-term potentiation; AMPA receptor; Endocytosis; Neuroscience; Postsynaptic potential; Hippocampal formation; Biology; Chemistry; Cell biology; NMDA receptor; Receptor; Biochemistry","score_opus":0.12127804802204813,"score_gpt":0.4145816233990266,"score_spread":0.2933035753769785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966555773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9595462,0.024912734,0.010903865,0.0003269497,0.00009465554,0.0000722223,0.0002633087,0.00019007531,0.0036900088],"genre_scores_gemma":[0.9903273,0.00574907,0.0012899301,0.000085782696,0.000025013805,0.000060694598,0.00017169741,0.00001065357,0.002279756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998241,0.000014602679,0.000024436422,0.00003311221,0.00006312875,0.000040584862],"domain_scores_gemma":[0.99987733,0.000009655067,0.000050474864,0.000016998,0.000022824128,0.000022811571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021385921,0.00038309104,0.00047584157,0.00021442745,0.00019203131,0.00034852052,0.0003629854,0.00036655285,0.00045510632],"category_scores_gemma":[0.00023661678,0.00016120421,0.00044415504,0.00012565128,0.00036057853,0.00043032222,0.00032734047,0.00089851575,0.00027225947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041056963,0.000064400716,0.0010425407,0.00015264151,0.00003059041,0.00032826845,0.00003920484,0.0001039077,0.98436606,0.0006384865,0.00011362075,0.012709682],"study_design_scores_gemma":[0.00011750811,0.0011056087,0.073553234,0.00006923088,0.00010040539,0.0040670335,0.000115392126,0.0015091168,0.9111901,0.0018042654,0.006336712,0.00003141058],"about_ca_topic_score_codex":0.00065717904,"about_ca_topic_score_gemma":0.0006062629,"teacher_disagreement_score":0.00065717904,"about_ca_system_score_codex":0.0004974047,"about_ca_system_score_gemma":0.00031214766,"threshold_uncertainty_score":0.0036088824},"labels":[],"label_agreement":null},{"id":"W1967214137","doi":"10.1172/jci40259","title":"Engaging the lysosomal compartment to combat B cell malignancies","year":2009,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Response Biomedical (Canada)","funders":"Medical Research Council; Novo Nordisk; H. Lundbeck A/S; Lundbeckfonden; Sundhed og Sygdom, Det Frie Forskningsråd; Danmarks Grundforskningsfond; National Research Foundation; European Commission; Novo Nordisk Fonden; Kræftens Bekæmpelse","keywords":"CD20; Rituximab; B cell; Programmed cell death; Lymphoma; Medicine; Immunology; Lysosome; Monoclonal antibody; Cancer research; Apoptosis; Antibody; Biology","score_opus":0.1314796178940679,"score_gpt":0.406458272408917,"score_spread":0.27497865451484915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967214137","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012868489,0.025272822,0.0011243878,0.9194705,0.017984588,0.00007362816,0.00006200354,0.00021172466,0.022931844],"genre_scores_gemma":[0.14472492,0.026287371,0.0026231033,0.7009361,0.08507798,0.00016676012,0.00008517119,0.000048184822,0.040050417],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99960357,0.00016346166,0.0000391572,0.000034949742,0.00009969919,0.000059046157],"domain_scores_gemma":[0.9994423,0.00028691202,0.000049403832,0.000028679644,0.000103711085,0.00008902686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047170464,0.00043895474,0.0005194148,0.00026556355,0.0007769875,0.00077844533,0.00040643956,0.009188614,0.002570599],"category_scores_gemma":[0.0028534958,0.00020064457,0.00036752474,0.00017484366,0.00081150356,0.000990389,0.00035660158,0.0058218474,0.0032397597],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002956722,0.00022531384,0.0026020084,0.00033446366,0.000035137316,0.023077117,0.00017848797,0.0003190491,0.0055507715,0.006417315,0.86290586,0.09805885],"study_design_scores_gemma":[0.0006496047,0.00052526087,0.002748658,0.00025139278,0.00004250612,0.06282413,0.0002570066,0.0017854739,0.00361017,0.013035938,0.9142329,0.00003695208],"about_ca_topic_score_codex":0.00040377243,"about_ca_topic_score_gemma":0.0009541292,"teacher_disagreement_score":0.009188614,"about_ca_system_score_codex":0.0012247715,"about_ca_system_score_gemma":0.00052789313,"threshold_uncertainty_score":0.008886397},"labels":[],"label_agreement":null},{"id":"W1967494982","doi":"10.1172/jci10564","title":"Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":537,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Children's Hospital; McGill University; Women's Health Research Institute","funders":"Canadian Arthritis Network; Medical Research Council; National Institute on Aging; National Institutes of Health; Medical Research Council Canada; Shriners Hospitals for Children","keywords":"Collagenase; Cartilage; Osteoarthritis; Matrix metalloproteinase; Hyaline; Proteoglycan; Synovitis; Hyaline cartilage; Transgene; Pathology; Metalloproteinase; Type II collagen; MMP1; Chemistry; Cell biology; Biology; Gene expression; Medicine; Arthritis; Immunology; Internal medicine; Anatomy; Articular cartilage; Gene; Enzyme; Biochemistry","score_opus":0.06738610853385885,"score_gpt":0.3666802277330138,"score_spread":0.29929411919915494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967494982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98512244,0.0019055032,0.0072548985,0.0003515462,0.00008961603,0.00028002777,0.0013684994,0.0006061183,0.0030214116],"genre_scores_gemma":[0.96869946,0.0023765736,0.011502086,0.00022117946,0.00006453845,0.00045668503,0.002239815,0.00026043822,0.014179246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921215,0.0001330772,0.00011345686,0.0001360309,0.00020514741,0.0002001549],"domain_scores_gemma":[0.99898,0.00016585457,0.00032822546,0.00010267234,0.000074053314,0.00034914006],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073038985,0.0008646383,0.00057487463,0.0014343453,0.0004063431,0.0006822502,0.00062090886,0.0011466421,0.002689324],"category_scores_gemma":[0.00038004047,0.0007507288,0.00064613466,0.0004594773,0.0009081288,0.0004785656,0.00043600865,0.0020466188,0.0013051311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000359502,0.00024008354,0.00019461369,0.000046392888,0.000008484227,0.00014195654,0.000039896753,0.00004630108,0.99740714,0.00027436606,0.00006607777,0.0011752254],"study_design_scores_gemma":[0.00034752281,0.002190236,0.0046616606,0.000048776248,0.000068328714,0.00083140034,0.00006953347,0.0011104747,0.98580754,0.00021525215,0.004633536,0.00001576636],"about_ca_topic_score_codex":0.0009875854,"about_ca_topic_score_gemma":0.0017272425,"teacher_disagreement_score":0.002689324,"about_ca_system_score_codex":0.0007108082,"about_ca_system_score_gemma":0.00049816415,"threshold_uncertainty_score":0.008996725},"labels":[],"label_agreement":null},{"id":"W1967814408","doi":"10.1172/jci68016","title":"Rare variants in single-minded 1 (SIM1) are associated with severe obesity","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":168,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Ottawa; Medical Research Council; National Institute for Health and Care Research; NIHR Cambridge Biomedical Research Centre; Australian Research Council; Wellcome Trust; National Heart, Lung, and Blood Institute; McGill University","keywords":"Endocrinology; Biology; Internal medicine; Penetrance; Phenotype; Melanocortin 4 receptor; Proband; Obesity; Transcription factor; Melanocortin; Genetics; Gene; Mutation; Medicine; Hormone","score_opus":0.1018626256976997,"score_gpt":0.32208196175931886,"score_spread":0.22021933606161914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967814408","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991762,0.00015549867,0.00031824448,0.000027501723,0.000005698975,0.000006532225,0.00006743756,0.000018283305,0.00022452042],"genre_scores_gemma":[0.9991985,0.000100868165,0.00033248248,0.000020734466,0.000014923855,0.000004015261,0.00012479573,0.000009688011,0.0001939795],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99961483,0.000056330464,0.000053880336,0.00013819885,0.000083304716,0.00005343708],"domain_scores_gemma":[0.9992812,0.00019467334,0.00030638685,0.000038759063,0.000029102486,0.00014990717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000189302,0.0013991478,0.00052881346,0.0013187452,0.0005787657,0.00040150632,0.00048319157,0.0007707837,0.0024247111],"category_scores_gemma":[0.0014545802,0.000446951,0.00039928465,0.0008678946,0.00083153497,0.00023386431,0.0005663991,0.0005742055,0.00033925974],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036833931,0.0003889937,0.66181403,0.00020128179,0.0007529964,0.10665642,0.0014105764,0.0009875072,0.20243333,0.001292916,0.0012747998,0.019103816],"study_design_scores_gemma":[0.0001690935,0.0009323441,0.727358,0.00005903832,0.00036884524,0.25370204,0.0005102168,0.0013671642,0.01278776,0.00092198,0.0017515938,0.00007201657],"about_ca_topic_score_codex":0.00081928,"about_ca_topic_score_gemma":0.0009773164,"teacher_disagreement_score":0.0024247111,"about_ca_system_score_codex":0.00019264089,"about_ca_system_score_gemma":0.00015580114,"threshold_uncertainty_score":0.008111477},"labels":[],"label_agreement":null},{"id":"W1967914509","doi":"10.1172/jci18234","title":"Heparan sulfate: Antithrombotic or not?","year":2003,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hamilton Health Sciences","funders":"McMaster University; Heart and Stroke Foundation of Canada","keywords":"Heparan sulfate; Antithrombotic; Chemistry; Heparin; Sulfate; Cell biology; Biochemistry; Medicine; Biology; Internal medicine","score_opus":0.4336635917477718,"score_gpt":0.5189502674382912,"score_spread":0.0852866756905194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967914509","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012481531,0.9989655,0.000045675548,0.0002616347,0.00016915878,0.0000018437464,0.000009155762,0.0000030642177,0.0004192126],"genre_scores_gemma":[0.00091151375,0.99808645,0.00007176656,0.00018262309,0.00021005502,0.000002932951,0.00001768207,6.0926953e-7,0.0005163569],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99989104,0.000020715424,0.000022079586,0.00001469644,0.00004108924,0.000010322591],"domain_scores_gemma":[0.9997805,0.00009445557,0.000046690227,0.0000070798383,0.000047084886,0.000024211324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040243537,0.0008061531,0.0016738201,0.0015052088,0.00021291028,0.0007285658,0.00068962405,0.0008901805,0.0027592476],"category_scores_gemma":[0.000592438,0.00022717807,0.00026728015,0.0017698305,0.0005898831,0.0009547454,0.00036182007,0.0010593872,0.0017668566],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012183883,0.00004509817,0.000305074,0.009041539,0.00010428516,0.00045778038,0.00003719338,0.00015754475,0.0012178492,0.001470883,0.034983788,0.9520572],"study_design_scores_gemma":[0.000085003645,0.00015623802,0.0020272234,0.003604442,0.00025517915,0.005703856,0.0001584377,0.00013388888,0.00090734434,0.0023569043,0.98458636,0.000025053716],"about_ca_topic_score_codex":0.0012224527,"about_ca_topic_score_gemma":0.0026770707,"teacher_disagreement_score":0.0027592476,"about_ca_system_score_codex":0.00043210475,"about_ca_system_score_gemma":0.00065398973,"threshold_uncertainty_score":0.009230614},"labels":[],"label_agreement":null},{"id":"W1968091682","doi":"10.1172/jci58227","title":"Decreased cardiac L-type Ca2+ channel activity induces hypertrophy and heart failure in mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Cincinnati Children's Hospital Medical Center; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; American Heart Association; Howard Hughes Medical Institute","keywords":"Heart failure; Muscle hypertrophy; Internal medicine; Endocrinology; Calcineurin; Contractility; Pressure overload; Stimulation; Medicine; Cardiac function curve; Voltage-dependent calcium channel; Endoplasmic reticulum; Biology; Calcium; Cardiac hypertrophy; Cell biology; Transplantation","score_opus":0.0745738239697274,"score_gpt":0.3171909568913408,"score_spread":0.2426171329216134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968091682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832719,0.0011945948,0.007351191,0.00077500934,0.00017536171,0.000243045,0.0032980705,0.00083883846,0.0028521323],"genre_scores_gemma":[0.96999544,0.0020279165,0.008676162,0.0010586989,0.00012372009,0.0008652901,0.0034029263,0.0004289324,0.013420901],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992335,0.000092020324,0.000113535694,0.00023206165,0.00014712437,0.00018183018],"domain_scores_gemma":[0.99907756,0.0001243692,0.00034574195,0.00009273872,0.000048140762,0.00031144638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008210889,0.0011227743,0.000663001,0.0014533112,0.00051289453,0.0007710691,0.00081264373,0.0015057111,0.004707063],"category_scores_gemma":[0.00038888308,0.00086000084,0.001023865,0.00044922635,0.0011570592,0.00065154384,0.00057159347,0.0029598481,0.0014980678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005162213,0.0002596142,0.00048320642,0.00008200423,0.000021915426,0.00019584282,0.00008164792,0.000114904215,0.99652845,0.0003214845,0.00021149241,0.0011833869],"study_design_scores_gemma":[0.0010466945,0.005260824,0.039680585,0.00020281463,0.00021187316,0.0025674896,0.0004106697,0.004115161,0.9360859,0.0008606467,0.009479857,0.000077438184],"about_ca_topic_score_codex":0.0006573623,"about_ca_topic_score_gemma":0.0014444331,"teacher_disagreement_score":0.004707063,"about_ca_system_score_codex":0.00058707385,"about_ca_system_score_gemma":0.00042646046,"threshold_uncertainty_score":0.015746713},"labels":[],"label_agreement":null},{"id":"W1968904120","doi":"10.1172/jci46465","title":"The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Terry Fox Foundation; Howard Hughes Medical Institute; University of Manitoba; National Cancer Institute; CancerCare Manitoba Foundation; American Cancer Society; Broad Institute; Boston Foundation","keywords":"Myeloid leukemia; GSK-3; Biology; Leukemia; Cancer research; Small hairpin RNA; Myeloid; Cell growth; Signal transduction; Cell cycle; Cell biology; Cancer; Apoptosis; Genetics; Gene knockdown","score_opus":0.021440843138178987,"score_gpt":0.31475616345654023,"score_spread":0.2933153203183612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968904120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885697,0.0028374167,0.0040046973,0.00024192886,0.00004076457,0.00008791907,0.001185364,0.00021545464,0.002816719],"genre_scores_gemma":[0.99039066,0.00288463,0.0030548037,0.00013583367,0.000011834056,0.00006405941,0.0017440334,0.000022196624,0.0016919711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998596,0.000022245333,0.000013640318,0.000023753317,0.000060275288,0.000020510763],"domain_scores_gemma":[0.9999219,0.000026116302,0.000020786534,0.000010117552,0.0000065504673,0.00001453892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016244278,0.0004816417,0.00032922457,0.00043928207,0.00015419816,0.00031785923,0.00014695723,0.00019386144,0.0010318378],"category_scores_gemma":[0.00020446772,0.00017261437,0.00029395602,0.0003097352,0.00018436906,0.000084409316,0.00022041734,0.00036521486,0.00033350763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001328907,0.000051694984,0.0005093597,0.000037317615,0.000013394222,0.0000703793,0.0000053866584,0.00037765445,0.9951964,0.000108586944,0.00007084983,0.0034261295],"study_design_scores_gemma":[0.00006733793,0.0006978215,0.0072496766,0.000009409523,0.000051650215,0.00040811466,0.00001394655,0.0016228288,0.9870135,0.00015211292,0.0027074707,0.000006184042],"about_ca_topic_score_codex":0.0004971751,"about_ca_topic_score_gemma":0.0018486927,"teacher_disagreement_score":0.0010318378,"about_ca_system_score_codex":0.00032552582,"about_ca_system_score_gemma":0.0002977134,"threshold_uncertainty_score":0.0034518838},"labels":[],"label_agreement":null},{"id":"W1970410298","doi":"10.1172/jci65509","title":"Turning a blind eye to anti-VEGF toxicities","year":2012,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health; University of Toronto","keywords":"Macular degeneration; Medicine; Ophthalmology; Retinal; Diabetic retinopathy; Macular edema; Central retinal vein occlusion; Choroid; Retina; Retinal Vein; Branch retinal vein occlusion; Vascular endothelial growth factor A; VEGF receptors; Vascular endothelial growth factor; Neuroscience; Biology; Diabetes mellitus; Internal medicine; Endocrinology","score_opus":0.13855372972269991,"score_gpt":0.43069696831398324,"score_spread":0.2921432385912833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970410298","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0109796,0.028526653,0.002363258,0.89800423,0.037949476,0.000105323656,0.000063543346,0.00040339798,0.021604614],"genre_scores_gemma":[0.06407998,0.020030413,0.002334951,0.7916135,0.10579074,0.00010057696,0.000050761722,0.00006967586,0.0159294],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992188,0.00022843848,0.00008972823,0.00008276422,0.0002614244,0.00011884633],"domain_scores_gemma":[0.9979893,0.0011074195,0.0001549605,0.00013449199,0.00033789978,0.00027595283],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000893848,0.000773215,0.001031622,0.0005797581,0.0012455899,0.0015313114,0.00065330917,0.011881783,0.0026007362],"category_scores_gemma":[0.0078054564,0.00026151325,0.0008930048,0.0003456509,0.0018888185,0.0016268534,0.0007663815,0.013150596,0.0032342365],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004164623,0.00026502335,0.002682114,0.00046078308,0.00006573483,0.11631344,0.00038769038,0.00043539927,0.005101713,0.0112014515,0.7156549,0.14701521],"study_design_scores_gemma":[0.0004868316,0.00066008285,0.0035154193,0.00076081656,0.00005773083,0.17179921,0.00040970527,0.0010595035,0.0025409902,0.027303157,0.7913094,0.00009706147],"about_ca_topic_score_codex":0.00073648506,"about_ca_topic_score_gemma":0.0014696801,"teacher_disagreement_score":0.011881783,"about_ca_system_score_codex":0.0013852629,"about_ca_system_score_gemma":0.00063827645,"threshold_uncertainty_score":0.010050774},"labels":[],"label_agreement":null},{"id":"W1971308765","doi":"10.1172/jci57158","title":"Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling","year":2011,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":680,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Versus Arthritis; Exzellenzclusters Entzündungsforschung; Deutsche Forschungsgemeinschaft; Wellcome Trust","keywords":"Glycoprotein 130; Blockade; Tocilizumab; Autoimmunity; Immunology; Medicine; Regulator; Inflammation; Receptor; Disease; Cytokine; Interleukin-6 receptor; Antibody; Interleukin 6; Biology; Internal medicine; Rheumatoid arthritis","score_opus":0.4989451167644811,"score_gpt":0.5224018989622837,"score_spread":0.023456782197802617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971308765","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002504676,0.9962346,0.0006345845,0.0006326415,0.00032884092,0.000018535118,0.000017508777,0.000018808556,0.0018640363],"genre_scores_gemma":[0.0015191738,0.9951336,0.0011719377,0.0006307291,0.00033881917,0.00003283755,0.00005152989,0.0000035452822,0.0011177941],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998472,0.000033322558,0.000019157502,0.000021926597,0.00006021812,0.000018145518],"domain_scores_gemma":[0.99983394,0.00007446818,0.000024159224,0.000007741194,0.000038909457,0.000020787302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067416223,0.00092842954,0.0012137041,0.0017254271,0.0002766594,0.00073957647,0.0008289997,0.0014102679,0.0039704796],"category_scores_gemma":[0.00044736938,0.00023593823,0.0005505741,0.00092095265,0.0005758667,0.0010873642,0.00062195124,0.0031768763,0.003029688],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013337296,0.0002526226,0.0001366588,0.008295722,0.00008245129,0.0005449466,0.000067103865,0.0004910608,0.0087576965,0.008753113,0.0345265,0.93795866],"study_design_scores_gemma":[0.00009113843,0.000215499,0.00057058653,0.0016270154,0.00007286431,0.002255528,0.0000363,0.00013405735,0.0011112706,0.0028678735,0.99099827,0.000019680656],"about_ca_topic_score_codex":0.00035773616,"about_ca_topic_score_gemma":0.00093822327,"teacher_disagreement_score":0.0039704796,"about_ca_system_score_codex":0.0005340119,"about_ca_system_score_gemma":0.000752585,"threshold_uncertainty_score":0.013282537},"labels":[],"label_agreement":null},{"id":"W1972066347","doi":"10.1172/jci39387","title":"Tregs control the development of symptomatic West Nile virus infection in humans and mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":217,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"U.S. Public Health Service; National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention","keywords":"Asymptomatic; Immunology; Encephalitis; Disease; West Nile virus; Virology; Medicine; Viral encephalitis; Virus; Biology; Internal medicine","score_opus":0.04275139605037645,"score_gpt":0.36376327152685467,"score_spread":0.32101187547647825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972066347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957847,0.0014146724,0.0011908232,0.00007340494,0.000027816159,0.000037945054,0.00010764749,0.000043764256,0.0013193121],"genre_scores_gemma":[0.9979796,0.00037413472,0.0005419683,0.000069314374,0.000018617835,0.000040939925,0.0000885984,0.000009057422,0.0008778287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983335,0.00006221417,0.000011288367,0.000032909804,0.000022440609,0.000037713035],"domain_scores_gemma":[0.9998759,0.000016264965,0.00003957779,0.000023011684,0.0000088874785,0.000036262725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032303864,0.00026735532,0.00022562362,0.00024309955,0.00015558663,0.00021937386,0.00012317815,0.00022054621,0.0010477623],"category_scores_gemma":[0.00029450387,0.00017625623,0.00013029942,0.000064093736,0.00029322266,0.00012857153,0.00018517507,0.0004382233,0.00024136876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035375338,0.00059465284,0.009166857,0.00009048898,0.000026362666,0.00036824876,0.00024762118,0.00035996726,0.96273065,0.000690162,0.00053809007,0.021649335],"study_design_scores_gemma":[0.0017791939,0.014721711,0.2642177,0.00022596648,0.00023314275,0.008448568,0.0009824452,0.009799169,0.6697463,0.0040504253,0.025693662,0.000101777754],"about_ca_topic_score_codex":0.00018425341,"about_ca_topic_score_gemma":0.0003287331,"teacher_disagreement_score":0.0010477623,"about_ca_system_score_codex":0.000112131944,"about_ca_system_score_gemma":0.00014193049,"threshold_uncertainty_score":0.0035051107},"labels":[],"label_agreement":null},{"id":"W1972078981","doi":"10.1172/jci12348","title":"Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"GLUT4; Membrane ruffling; Cell biology; Actin remodeling; Glucose transporter; Biology; Glucose uptake; Actin; Cell membrane; Actin cytoskeleton; Insulin; Cytoskeleton; Cell; Endocrinology; Biochemistry","score_opus":0.06725942748888296,"score_gpt":0.3216743892972904,"score_spread":0.25441496180840745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972078981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99697745,0.00053946604,0.0013660418,0.00007178958,0.00001016524,0.000009459326,0.00005803427,0.000052227733,0.0009153765],"genre_scores_gemma":[0.99784255,0.00039878994,0.0005751767,0.000025109774,0.0000062446566,0.000010697932,0.000102915306,0.000010477357,0.0010279971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991286,0.000016002858,0.0000048956163,0.000015054987,0.00001729711,0.00003395031],"domain_scores_gemma":[0.9998996,0.000015298241,0.000030063311,0.0000128457905,0.000010609249,0.000031586493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008772289,0.0001818138,0.00015198303,0.00018261978,0.0001682297,0.00028609345,0.00011669625,0.00021091482,0.001168163],"category_scores_gemma":[0.00011856752,0.00015254343,0.00019419982,0.000099111705,0.00017179713,0.00015366302,0.00022340976,0.00039354034,0.00038952808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008449232,0.000017584698,0.00028515127,0.000012712008,0.0000028585534,0.00011020475,0.0000066515295,0.000023004694,0.99865925,0.000046110963,0.000024166326,0.0007277972],"study_design_scores_gemma":[0.000038801736,0.00020885037,0.021197408,0.0000069979565,0.000011173076,0.0006129486,0.00005130125,0.0009100985,0.9754664,0.00008597063,0.0014061234,0.0000039365314],"about_ca_topic_score_codex":0.00019965105,"about_ca_topic_score_gemma":0.00027659873,"teacher_disagreement_score":0.001168163,"about_ca_system_score_codex":0.0002367912,"about_ca_system_score_gemma":0.00007328775,"threshold_uncertainty_score":0.003907919},"labels":[],"label_agreement":null},{"id":"W1972097313","doi":"10.1172/jci59725","title":"Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8+ T cells and activating Foxp3+ regulatory T cells","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Contact Dermatitis and Allergies","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale","keywords":"Immunology; FOXP3; CD8; Adoptive cell transfer; Allergic contact dermatitis; Cytotoxic T cell; Immune tolerance; Sensitization; Immune system; T cell; Population; Langerhans cell; Contact dermatitis; Biology; Allergy; Medicine; Biochemistry","score_opus":0.044293045183474836,"score_gpt":0.3119760351722051,"score_spread":0.2676829899887303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972097313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98834586,0.0031152337,0.0037898002,0.00038763866,0.00016539556,0.00015050106,0.00034880693,0.0005794326,0.0031172798],"genre_scores_gemma":[0.9875729,0.0021123302,0.003881657,0.00038466393,0.00010602851,0.0002027599,0.0003535103,0.000067922025,0.005318202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997509,0.00004281134,0.00002503377,0.000064054984,0.00004544618,0.00007177794],"domain_scores_gemma":[0.99976784,0.000027991098,0.00007371564,0.00003755305,0.000020275089,0.00007253348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002935035,0.0007853433,0.0003917599,0.00056625606,0.00021097739,0.00032391632,0.00024766722,0.00064103876,0.0015996813],"category_scores_gemma":[0.0001617488,0.0002747809,0.00027417718,0.00015569838,0.00043943245,0.00039479422,0.00018980245,0.0013355331,0.00046332914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006370515,0.00033150954,0.00020144437,0.00007328551,0.000005735886,0.00006995401,0.000041235882,0.00009393629,0.9944301,0.000148875,0.00011883473,0.0038479897],"study_design_scores_gemma":[0.00057454617,0.0067034336,0.0052933865,0.00006440938,0.000057792717,0.0006393707,0.00007938977,0.0019066907,0.97809553,0.0004281393,0.0061427252,0.000014584527],"about_ca_topic_score_codex":0.00034521206,"about_ca_topic_score_gemma":0.000448387,"teacher_disagreement_score":0.0015996813,"about_ca_system_score_codex":0.00017552201,"about_ca_system_score_gemma":0.00029294772,"threshold_uncertainty_score":0.005351424},"labels":[],"label_agreement":null},{"id":"W1973159660","doi":"10.1172/jci63711","title":"Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"","keywords":"Endocytosis; Clathrin; Cell biology; Biology; Transferrin receptor; Internalization; GTPase; Receptor; Biochemistry","score_opus":0.029027398486931578,"score_gpt":0.2953151763103939,"score_spread":0.2662877778234623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973159660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952232,0.0007898868,0.0019064988,0.00012131382,0.000024160176,0.0000430173,0.00075902895,0.00024615286,0.00088673615],"genre_scores_gemma":[0.9945411,0.000971149,0.0016143577,0.000055653607,0.000020322512,0.00004462397,0.00061678234,0.000074637355,0.0020613351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99971265,0.000062073974,0.000044685523,0.000082491424,0.00005451071,0.000043553995],"domain_scores_gemma":[0.9995271,0.00007364133,0.00023760155,0.000022618226,0.000013174022,0.00012589942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020603294,0.0013121977,0.00039035856,0.0019682944,0.00032467875,0.00044886422,0.0003754819,0.0010188037,0.003170646],"category_scores_gemma":[0.00026324307,0.00060967123,0.00037634504,0.0005185187,0.00058453396,0.00026143374,0.0004752641,0.0008740179,0.00068332814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030141106,0.00009070955,0.0013329971,0.00004868728,0.000030507323,0.0012472,0.000050941857,0.00020829232,0.9947725,0.00031053496,0.00010317227,0.0015031477],"study_design_scores_gemma":[0.00023406476,0.0020927705,0.079658106,0.0001369125,0.00032273502,0.026142005,0.0003358481,0.0054696496,0.8758015,0.0010864804,0.008647555,0.00007239415],"about_ca_topic_score_codex":0.00069306797,"about_ca_topic_score_gemma":0.0010085093,"teacher_disagreement_score":0.003170646,"about_ca_system_score_codex":0.00039133904,"about_ca_system_score_gemma":0.00025095843,"threshold_uncertainty_score":0.010606825},"labels":[],"label_agreement":null},{"id":"W1973171955","doi":"10.1172/jci63679","title":"Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kidney Stones and Urolithiasis Treatments","field":"Medicine","cited_by":459,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Institute of Infection and Immunity","funders":"National Institute on Deafness and Other Communication Disorders; Deutsche Forschungsgemeinschaft","keywords":"Inflammation; Nephrocalcinosis; Calcium oxalate; Kidney; Secretion; Nephropathy; Diabetic nephropathy; Medicine; Endocrinology; Internal medicine; Immunology; Calcium; Diabetes mellitus","score_opus":0.08804786696183649,"score_gpt":0.3824316605644724,"score_spread":0.29438379360263595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973171955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951148,0.0018475252,0.001443428,0.00017572146,0.000026566026,0.00006440832,0.00011748821,0.000073138726,0.0011369162],"genre_scores_gemma":[0.9963993,0.0008263295,0.001432983,0.000089511144,0.000016863421,0.000050838113,0.00012315085,0.000007897948,0.0010530853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974734,0.000060721755,0.000035352103,0.000026604694,0.00006501869,0.000064831824],"domain_scores_gemma":[0.99987197,0.000017683491,0.00005197873,0.000015149109,0.000013602827,0.00002960507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025793657,0.00033263216,0.0003993823,0.00025695743,0.00015654693,0.00031898366,0.000111818124,0.00032885533,0.0011478853],"category_scores_gemma":[0.0002298582,0.00016630926,0.00037251267,0.00016932774,0.00034384817,0.00022741688,0.0003001939,0.0006447582,0.00018926988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005868247,0.0001332378,0.0006192926,0.00009592623,0.000009386917,0.0001445662,0.000044740722,0.00006339496,0.99507517,0.00009507594,0.000069386915,0.003062988],"study_design_scores_gemma":[0.0005478123,0.0022830619,0.020088054,0.000032658252,0.000042466872,0.0011480992,0.00012386958,0.0017228116,0.97077215,0.00038229662,0.0028450612,0.000011669138],"about_ca_topic_score_codex":0.0003663122,"about_ca_topic_score_gemma":0.0005963655,"teacher_disagreement_score":0.0011478853,"about_ca_system_score_codex":0.00024679882,"about_ca_system_score_gemma":0.00037576674,"threshold_uncertainty_score":0.0038400888},"labels":[],"label_agreement":null},{"id":"W1973489602","doi":"10.1172/jci30076","title":"The role of gut hormones in glucose homeostasis","year":2007,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":612,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Diabetes Canada; University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research; University of Toronto; Canadian Diabetes Association","keywords":"Enteroendocrine cell; Glucose homeostasis; Hormone; Energy homeostasis; Gastrointestinal tract; Homeostasis; Biology; Endocrine system; Assimilation (phonology); Motility; Gut flora; Endocrinology; Pancreas; Internal medicine; Diabetes mellitus; Insulin resistance; Cell biology; Medicine; Immunology; Obesity; Biochemistry","score_opus":0.15915421104129526,"score_gpt":0.44475498519862605,"score_spread":0.28560077415733076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973489602","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012802325,0.99850875,0.0000998579,0.00019266827,0.00021189368,0.000002414466,0.0000038589715,0.0000061585442,0.0008463862],"genre_scores_gemma":[0.00082888646,0.99830747,0.00013200348,0.00011391647,0.00023408586,0.0000030411668,0.0000062759673,7.0111724e-7,0.00037352342],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99978846,0.000044569995,0.000029001363,0.000029003575,0.0000868424,0.000022139839],"domain_scores_gemma":[0.9998185,0.000076209195,0.000025024627,0.000007227859,0.00004814225,0.000024906154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005916601,0.00085264747,0.0014643031,0.0012720022,0.00034227077,0.0008844231,0.0007453603,0.0011692663,0.002230426],"category_scores_gemma":[0.00050879753,0.00020159187,0.00032844458,0.0016740097,0.00068908004,0.0011751854,0.0006669905,0.0015874153,0.0023772789],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009122326,0.000078932244,0.00024519148,0.005196142,0.000053894095,0.0006299678,0.000075368764,0.00028329794,0.0029361981,0.0030475645,0.018724224,0.96863794],"study_design_scores_gemma":[0.000030211715,0.00016013652,0.001859817,0.0028074887,0.00007406252,0.0038105252,0.00012565017,0.00008222834,0.0011428415,0.0037035004,0.98617953,0.000023955587],"about_ca_topic_score_codex":0.0007535018,"about_ca_topic_score_gemma":0.00092342077,"teacher_disagreement_score":0.002230426,"about_ca_system_score_codex":0.00052644394,"about_ca_system_score_gemma":0.0008582727,"threshold_uncertainty_score":0.007461548},"labels":[],"label_agreement":null},{"id":"W1973693466","doi":"10.1172/jci66168","title":"iRHOM2 is a critical pathogenic mediator of inflammatory arthritis","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":168,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; U.S. Public Health Service; Deutsche Forschungsgemeinschaft; Alexander von Humboldt-Stiftung","keywords":"Mediator; Arthritis; Inflammatory mediator; Inflammation; Medicine; Immunology; Internal medicine","score_opus":0.06947756794983849,"score_gpt":0.3834276023807282,"score_spread":0.3139500344308897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973693466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97587365,0.010540926,0.0040121656,0.00054934516,0.00014344617,0.000054098105,0.0006973279,0.00024756475,0.007881504],"genre_scores_gemma":[0.99198896,0.0015346466,0.0015125035,0.0001089366,0.00005910784,0.000020033323,0.0006135335,0.000019289833,0.004142892],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988544,0.000018855619,0.000008805239,0.000030920986,0.000031145915,0.000024799905],"domain_scores_gemma":[0.9999144,0.000008782062,0.000029734165,0.0000075129287,0.0000071669588,0.000032403757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014016702,0.00039059046,0.0002219173,0.00022531621,0.00025312428,0.00028209997,0.00018584404,0.00042096913,0.0027256215],"category_scores_gemma":[0.000109948465,0.00011964489,0.00014151804,0.00012787472,0.00022700353,0.00016840722,0.00025185995,0.00060635625,0.0006720764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003517754,0.00004328558,0.001476738,0.00009206471,0.000010843689,0.0012402403,0.000015321702,0.00004848597,0.99130476,0.000274758,0.0003204383,0.0048211943],"study_design_scores_gemma":[0.00015604797,0.0010613104,0.044640582,0.00005129233,0.00007840047,0.018447543,0.00011381848,0.0010429816,0.89306086,0.00042363576,0.040901877,0.000021633432],"about_ca_topic_score_codex":0.00011729421,"about_ca_topic_score_gemma":0.00011542156,"teacher_disagreement_score":0.0027256215,"about_ca_system_score_codex":0.00021235843,"about_ca_system_score_gemma":0.00013432327,"threshold_uncertainty_score":0.00911814},"labels":[],"label_agreement":null},{"id":"W1974586799","doi":"10.1172/jci25148","title":"Caffey disease: an unlikely collagenopathy","year":2005,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Osteomyelitis and Bone Disorders Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada; Montreal Children's Hospital","funders":"Shriners Hospitals for Children; McGill University","keywords":"Osteogenesis imperfecta; Missense mutation; Hyperostosis; Dentinogenesis imperfecta; Connective tissue; Pathology; Ehlers–Danlos syndrome; Mutation; Medicine; Genetics; Biology; Anatomy; Gene","score_opus":0.14117605227772934,"score_gpt":0.43565172704036237,"score_spread":0.29447567476263303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974586799","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23600395,0.018871654,0.00205768,0.6505717,0.025917666,0.00024155938,0.00027362737,0.00023597007,0.065826155],"genre_scores_gemma":[0.7243612,0.011026789,0.00156761,0.13176939,0.11386286,0.00011496859,0.00012389549,0.00004685514,0.017126404],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9993167,0.00013755655,0.000065294786,0.00015909142,0.00013814827,0.00018316969],"domain_scores_gemma":[0.998201,0.0009472676,0.00024848428,0.000078253055,0.00021926193,0.00030564002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006188765,0.0009421778,0.0010162678,0.0006414137,0.0017521215,0.0011616666,0.00092294667,0.014733763,0.0030674955],"category_scores_gemma":[0.00795096,0.000431031,0.0005413288,0.00043969642,0.0015445807,0.0016425633,0.00048337746,0.0046229507,0.0010106137],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018111632,0.000108150125,0.00987775,0.00017151234,0.000038071797,0.92432,0.00031293544,0.00017175442,0.0011816402,0.004549922,0.047355015,0.011732198],"study_design_scores_gemma":[0.00029106904,0.00018171397,0.010057044,0.00020236408,0.000055768385,0.9289031,0.0004214797,0.0011526999,0.00055409776,0.0057235365,0.05242268,0.00003450192],"about_ca_topic_score_codex":0.0017161929,"about_ca_topic_score_gemma":0.002516003,"teacher_disagreement_score":0.014733763,"about_ca_system_score_codex":0.0016714442,"about_ca_system_score_gemma":0.0007023086,"threshold_uncertainty_score":0.01212728},"labels":[],"label_agreement":null},{"id":"W1975675431","doi":"10.1172/jci37785","title":"Possible dual roles for prostacyclin in human pregnancy and labor","year":2008,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Newcastle University","keywords":"Myometrium; Prostacyclin; Smooth muscle; Uterus; Stimulation; Prostaglandin; Endocrinology; Internal medicine; Pregnancy; Biology; Cell biology; Medicine","score_opus":0.08327798050714554,"score_gpt":0.38388578994822486,"score_spread":0.30060780944107934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975675431","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12370861,0.13914135,0.0018845615,0.6758005,0.015702933,0.00007442927,0.00008190054,0.0001307583,0.043474995],"genre_scores_gemma":[0.6515173,0.04413465,0.0017043967,0.18893646,0.104622744,0.00012871972,0.000079974205,0.000035212874,0.008840502],"study_design_codex":"case_report","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991435,0.00037221404,0.00010723476,0.00010284948,0.0001551995,0.000119003176],"domain_scores_gemma":[0.9979226,0.0015235281,0.00019206604,0.00010774895,0.000082660794,0.00017132304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001173815,0.0003649987,0.00096132327,0.00048759862,0.0007854627,0.0012754101,0.0005855997,0.0099635925,0.0018920656],"category_scores_gemma":[0.0054756515,0.00031141198,0.00030054644,0.0004061584,0.00229476,0.0014239121,0.0006395439,0.0043393564,0.0008004077],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041131815,0.0004398225,0.044848505,0.0013817163,0.00010728381,0.5591818,0.0039052032,0.00055201596,0.015642485,0.07214275,0.1597667,0.13791852],"study_design_scores_gemma":[0.0009467977,0.0008935286,0.024324274,0.0010426705,0.00009374598,0.46188238,0.002138187,0.0016810052,0.005191738,0.054439336,0.4472546,0.000111667745],"about_ca_topic_score_codex":0.00024952737,"about_ca_topic_score_gemma":0.0004050715,"teacher_disagreement_score":0.0099635925,"about_ca_system_score_codex":0.0016204177,"about_ca_system_score_gemma":0.00052889285,"threshold_uncertainty_score":0.011756957},"labels":[],"label_agreement":null},{"id":"W1975748957","doi":"10.1172/jci31095","title":"FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":332,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Cancer Institute; D. Warren Brown Family Foundation; Associazione Italiana per la Ricerca sul Cancro; Fonds de Recherche du Québec - Santé; Ministero della Salute; Ohio State University; American-Italian Cancer Foundation","keywords":"Chronic myelogenous leukemia; Cancer research; Philadelphia chromosome; Leukemia; Dasatinib; Progenitor cell; Medicine; Myeloid leukemia; Immunology; Imatinib; Stem cell; Biology","score_opus":0.052966102490439086,"score_gpt":0.3724998987889664,"score_spread":0.3195337962985273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975748957","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8434346,0.1372796,0.0049017984,0.0014823085,0.0004668939,0.00022566544,0.00058752345,0.00053746667,0.011084157],"genre_scores_gemma":[0.9610122,0.030009618,0.0021963844,0.00031737162,0.00014556643,0.00008927826,0.0007645739,0.000013476457,0.005451546],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99996626,0.000002927876,0.000002607877,0.000006626952,0.00001019446,0.00001128044],"domain_scores_gemma":[0.99998784,0.0000012197042,0.0000039272522,7.720108e-7,0.0000012728428,0.000004962083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000067822424,0.00029488766,0.0002458064,0.00032208257,0.00015745082,0.00021450657,0.00023039049,0.00029629588,0.0010937143],"category_scores_gemma":[0.000040872277,0.000065913715,0.00018096199,0.00022556576,0.00015120232,0.00020869896,0.00014336332,0.0005146592,0.0002899059],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029801382,0.00083679444,0.0010870417,0.0007014935,0.00007975383,0.002097487,0.000095234805,0.0006903215,0.63333315,0.0025329299,0.0047918046,0.3507739],"study_design_scores_gemma":[0.0071458817,0.024311347,0.0294869,0.00016327015,0.00041628626,0.029862694,0.00015558723,0.0034201196,0.56827253,0.0016800617,0.33498314,0.000102118356],"about_ca_topic_score_codex":0.0006395927,"about_ca_topic_score_gemma":0.0020731052,"teacher_disagreement_score":0.0010937143,"about_ca_system_score_codex":0.00031249007,"about_ca_system_score_gemma":0.00019074968,"threshold_uncertainty_score":0.0036588311},"labels":[],"label_agreement":null},{"id":"W1976257390","doi":"10.1172/jci44564","title":"Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":180,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"NHLBI Division of Intramural Research; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; Feinberg School of Medicine; U.S. Department of Agriculture; Canadian Diabetes Association; National Cancer Institute; National Institutes of Health; March of Dimes Foundation; Northwestern University; Juvenile Diabetes Research Foundation International","keywords":"Endocrinology; Internal medicine; Lipid metabolism; Glucose homeostasis; Estrogen receptor; Biology; Pancreatic islets; Insulin; Estrogen; Insulin resistance; Type 2 diabetes; Islet; Pancreas; Diabetes mellitus; Medicine","score_opus":0.08489625709867195,"score_gpt":0.3146943365462345,"score_spread":0.2297980794475626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976257390","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894014,0.004192682,0.0029490413,0.00031403606,0.00020362117,0.00008532702,0.0008753008,0.00039976469,0.001578815],"genre_scores_gemma":[0.97897756,0.0075185318,0.003989305,0.00031885493,0.00006637853,0.00022988873,0.0017017398,0.00011779286,0.00707991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997832,0.000035447258,0.000031211,0.000037898153,0.000055982924,0.00005620584],"domain_scores_gemma":[0.9997812,0.000019101764,0.00006650159,0.000034632067,0.000018118988,0.000080522426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032682533,0.00070585613,0.0007051267,0.0007530858,0.00020985608,0.0003584194,0.00038348825,0.0005237632,0.0014300832],"category_scores_gemma":[0.00022626064,0.0003520046,0.000432642,0.00040544564,0.00035627352,0.00029033324,0.000236882,0.0012938608,0.00033090648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018793567,0.0004946992,0.0004628204,0.00011870986,0.00003938177,0.00007978137,0.000029163966,0.00016200573,0.9911131,0.00014332723,0.00019992888,0.0052777757],"study_design_scores_gemma":[0.00065016904,0.0076069026,0.011036883,0.000058980113,0.00016799291,0.0004143776,0.000135555,0.00072635355,0.97151595,0.00023855119,0.007419232,0.000028902752],"about_ca_topic_score_codex":0.00070328475,"about_ca_topic_score_gemma":0.0015768727,"teacher_disagreement_score":0.0014300832,"about_ca_system_score_codex":0.0002970245,"about_ca_system_score_gemma":0.00039335783,"threshold_uncertainty_score":0.004784167},"labels":[],"label_agreement":null},{"id":"W1976507289","doi":"10.1172/jci24898","title":"Small-molecule correctors of defective  F508-CFTR cellular processing identified by high-throughput screening","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":534,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Eye Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Cystic Fibrosis Foundation; University of California, San Francisco; National Institutes of Health","keywords":"Cystic fibrosis transmembrane conductance regulator; Chemistry; Cystic fibrosis; Mutant; Chloride channel; Biochemistry; Molecular biology; Biology; Gene","score_opus":0.0881346237300916,"score_gpt":0.3969814860429774,"score_spread":0.30884686231288583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976507289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.968998,0.01101976,0.012491883,0.0003069816,0.00007967164,0.00079251773,0.0019859255,0.00061923696,0.003706079],"genre_scores_gemma":[0.97310174,0.008855755,0.010196714,0.00017381407,0.000023960722,0.00036560767,0.0029762457,0.0000538225,0.0042522713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977833,0.00004005099,0.000016552038,0.00003288343,0.00010001939,0.000032193107],"domain_scores_gemma":[0.9998324,0.000055457363,0.000033773715,0.0000201249,0.000034699035,0.000023604627],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038230955,0.0005754399,0.0008674089,0.00051351794,0.00025660146,0.0004922959,0.00043373648,0.00044259802,0.0013502294],"category_scores_gemma":[0.00028087833,0.00021182759,0.0004136198,0.00049512164,0.00020731262,0.00018505045,0.000249828,0.00051121967,0.00046619368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024422296,0.00025304075,0.00077090424,0.00018204561,0.000048849106,0.00018761848,0.000019069075,0.00055964687,0.98554534,0.00011641145,0.00036512202,0.011707679],"study_design_scores_gemma":[0.00016779508,0.0030305628,0.0052236593,0.00001581768,0.00018691013,0.00075751217,0.000033960427,0.00203477,0.9817139,0.000061834115,0.006754424,0.00001887396],"about_ca_topic_score_codex":0.00055446243,"about_ca_topic_score_gemma":0.0022551066,"teacher_disagreement_score":0.0013502294,"about_ca_system_score_codex":0.00045443955,"about_ca_system_score_gemma":0.0003216622,"threshold_uncertainty_score":0.004516959},"labels":[],"label_agreement":null},{"id":"W1976819858","doi":"10.1172/jci21846","title":"EphB6-null mutation results in compromised T cell function","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"Canadian Institutes of Health Research; Université de Montréal; Roche Organ Transplant Research Foundation; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"Mutation; Function (biology); Computational biology; Biology; Genetics; Bioinformatics; Gene","score_opus":0.1541023220908831,"score_gpt":0.37287259020978414,"score_spread":0.21877026811890105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976819858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925487,0.0012416445,0.0026025614,0.00017329035,0.00007500785,0.000021492078,0.0014654186,0.00019834912,0.0016735749],"genre_scores_gemma":[0.9889369,0.0010959965,0.0026485252,0.00008792497,0.00003622878,0.000025043135,0.0011866352,0.000096108415,0.00588665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99971026,0.000043544755,0.000057045803,0.000063142994,0.00008126639,0.000044692322],"domain_scores_gemma":[0.9996598,0.00005095133,0.000113294205,0.000032092034,0.000016787246,0.00012699862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016121635,0.00056138483,0.00037236125,0.0004248354,0.00014754933,0.00039523857,0.00023263383,0.00069437135,0.0036625233],"category_scores_gemma":[0.00020335232,0.0002144761,0.00032376166,0.00016946909,0.00043796084,0.00027319218,0.00036263192,0.000903644,0.0014529839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021980662,0.000028078768,0.00024665348,0.000037516395,0.0000115138355,0.00052833464,0.0000124534745,0.00007846548,0.9973966,0.00016194531,0.00006502684,0.0012135495],"study_design_scores_gemma":[0.000079126294,0.00050784193,0.009012468,0.000022136463,0.000060475635,0.008981353,0.000059676076,0.0017079791,0.97382724,0.0003332733,0.005394195,0.000014227384],"about_ca_topic_score_codex":0.0001793343,"about_ca_topic_score_gemma":0.00022594612,"teacher_disagreement_score":0.0036625233,"about_ca_system_score_codex":0.00016998065,"about_ca_system_score_gemma":0.000109365305,"threshold_uncertainty_score":0.01225239},"labels":[],"label_agreement":null},{"id":"W1977576363","doi":"10.1172/jci13737","title":"The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins","year":2001,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada","keywords":"Hereditary multiple exostoses; Biology; Gene; Genetics; Heparan sulfate; Mutation; Skeletal disorder; Glycoprotein; Osteoporosis","score_opus":0.1533370374654977,"score_gpt":0.4285861005199525,"score_spread":0.2752490630544548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977576363","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11920388,0.86801493,0.005090479,0.0018609343,0.0001846242,0.000012449773,0.00012465699,0.00005294957,0.0054552173],"genre_scores_gemma":[0.41822895,0.5706887,0.004184944,0.0008328222,0.0008916355,0.000017939148,0.00023450347,0.000012690927,0.004907729],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99995327,0.000009128528,0.0000073847286,0.000010264949,0.000012528,0.0000074840223],"domain_scores_gemma":[0.9999057,0.00004097855,0.000027367221,0.000002605509,0.000012332845,0.000011021215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012667735,0.00021591896,0.00016906364,0.0003478782,0.000057915375,0.00019456736,0.00012114293,0.00032543307,0.00080211804],"category_scores_gemma":[0.00016109741,0.00004591459,0.000107738844,0.0002952438,0.00023105615,0.0002835804,0.00022766202,0.00028875616,0.00016620083],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000593183,0.00009441235,0.04244414,0.00440828,0.0002870398,0.034429226,0.00041053785,0.0006313025,0.22211221,0.018918058,0.0049893837,0.6706822],"study_design_scores_gemma":[0.000055100958,0.000991962,0.20340608,0.0010173221,0.0005410996,0.29490006,0.0006323224,0.0019013765,0.1090811,0.019661803,0.36770606,0.00010575938],"about_ca_topic_score_codex":0.00025341523,"about_ca_topic_score_gemma":0.00020457515,"teacher_disagreement_score":0.00080211804,"about_ca_system_score_codex":0.0001433882,"about_ca_system_score_gemma":0.00013337283,"threshold_uncertainty_score":0.002683401},"labels":[],"label_agreement":null},{"id":"W1979147243","doi":"10.1172/jci41789","title":"A molecular classifier for predicting future graft loss in late kidney transplant biopsies","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":212,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"","keywords":"Medicine; Kidney transplantation; Transplantation; Renal function; Internal medicine; Proteinuria; Pathology; Fibrosis; Kidney; Biopsy; Urology","score_opus":0.05198470743307953,"score_gpt":0.3741028219329813,"score_spread":0.32211811449990174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979147243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8432538,0.0010581568,0.14793676,0.0006750267,0.00016069907,0.00045291387,0.0025420391,0.0014406943,0.0024797972],"genre_scores_gemma":[0.92830276,0.0001918737,0.06794374,0.00010069261,0.000099269164,0.00025467374,0.0023031433,0.000020955833,0.0007828667],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9995165,0.00012892188,0.000071400194,0.00007318938,0.0001473118,0.000062761144],"domain_scores_gemma":[0.9975809,0.0013329812,0.0002759167,0.00009078658,0.0005873085,0.00013207052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015316294,0.00049988035,0.0006499676,0.002304919,0.0002517531,0.000737326,0.00043251892,0.00074887247,0.0008859932],"category_scores_gemma":[0.004964124,0.0001425014,0.0003380518,0.0005606752,0.00015710935,0.0003931985,0.00023530245,0.000612818,0.0005829436],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020051121,0.0011273809,0.4987201,0.00021249325,0.0003571663,0.00066585036,0.00012243282,0.06168345,0.029132525,0.000972263,0.008697761,0.3963034],"study_design_scores_gemma":[0.00011618305,0.00071186223,0.10098042,0.00006437775,0.00016942849,0.0009593899,0.00009816613,0.881978,0.010730916,0.0019663968,0.002175699,0.000049202972],"about_ca_topic_score_codex":0.0012746595,"about_ca_topic_score_gemma":0.0012146067,"teacher_disagreement_score":0.002304919,"about_ca_system_score_codex":0.00037466525,"about_ca_system_score_gemma":0.00045960548,"threshold_uncertainty_score":0.008100152},"labels":[],"label_agreement":null},{"id":"W1979904368","doi":"10.1172/jci23153","title":"Vasohibin: the feedback on a new inhibitor of angiogenesis","year":2004,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Angiogenesis; Angiogenesis inhibitor; Endogeny; Cell biology; VEGF receptors; Chemistry; Vascular endothelial growth factor; Endothelial stem cell; Cancer research; Pharmacology; Biology; Biochemistry; In vitro","score_opus":0.06983046712822628,"score_gpt":0.34469650687594156,"score_spread":0.2748660397477153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979904368","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06651649,0.12592949,0.0056907455,0.70247483,0.047264166,0.00029879625,0.0002924481,0.00042293678,0.051110048],"genre_scores_gemma":[0.3916553,0.05252841,0.004741457,0.39744323,0.09951169,0.00036371313,0.00030051885,0.00008798057,0.053367656],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99963045,0.00010691727,0.00003502813,0.000057458485,0.00011245385,0.000057612564],"domain_scores_gemma":[0.9995358,0.00027053096,0.000048564387,0.000022068187,0.00005208688,0.00007093963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005054667,0.00052805163,0.0006218481,0.00021613811,0.00050296966,0.0008948909,0.00050873007,0.0063100364,0.0019214619],"category_scores_gemma":[0.0015322486,0.00016676579,0.00036237997,0.00016695673,0.0011045409,0.0007733027,0.00028208893,0.004266583,0.0015251226],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003836855,0.0004645622,0.0068598716,0.0013667193,0.00012956798,0.11738677,0.00032792595,0.0006498857,0.06331645,0.035067078,0.515412,0.2551824],"study_design_scores_gemma":[0.00093690446,0.0010452014,0.003653966,0.00020568952,0.000095832744,0.08680532,0.00014759584,0.0011073288,0.024599385,0.010396997,0.8709477,0.00005806815],"about_ca_topic_score_codex":0.00021423676,"about_ca_topic_score_gemma":0.0003663885,"teacher_disagreement_score":0.0063100364,"about_ca_system_score_codex":0.0011854797,"about_ca_system_score_gemma":0.0003996266,"threshold_uncertainty_score":0.008601248},"labels":[],"label_agreement":null},{"id":"W1980006442","doi":"10.1172/jci8934","title":"The viral anti-inflammatory chemokine-binding protein M-T7 reduces intimal hyperplasia after vascular injury","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Viron Therapeutics (Canada); Robarts Clinical Trials; University of Alberta; Western University","funders":"Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Intimal hyperplasia; Restenosis; Chemokine; Neointimal hyperplasia; Medicine; Angioplasty; Immunology; Inflammation; Pathology; Internal medicine; Stent","score_opus":0.01917961535525104,"score_gpt":0.30508674984408773,"score_spread":0.2859071344888367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980006442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99711823,0.0012904011,0.00047984792,0.000069297486,0.000026675089,0.000021321477,0.000033630287,0.000046340498,0.0009143549],"genre_scores_gemma":[0.99527174,0.0012870715,0.0012775513,0.000060560244,0.000049452257,0.000043676937,0.00021229441,0.000017391088,0.0017802797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978,0.00005945118,0.000013843017,0.000017033892,0.000056652534,0.000073094125],"domain_scores_gemma":[0.99981123,0.000030488207,0.000044899043,0.000020226373,0.00002309638,0.00006998209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001786937,0.00046750423,0.000497774,0.00031327282,0.00015653498,0.0002620556,0.00023964046,0.0004521046,0.0007924009],"category_scores_gemma":[0.00031141998,0.00015489846,0.0001917051,0.00013107853,0.00032015386,0.00020091084,0.00013894356,0.0007480815,0.0003017681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023608657,0.00078265916,0.00035388744,0.00006206924,0.000018686556,0.0000549568,0.000023960947,0.00009793932,0.98991054,0.00009091962,0.000089113724,0.0061544883],"study_design_scores_gemma":[0.00034036257,0.017515963,0.008723767,0.000022623737,0.00007634703,0.00034922015,0.00006011138,0.0016150587,0.96974677,0.00009291393,0.0014489441,0.000008030236],"about_ca_topic_score_codex":0.00037442957,"about_ca_topic_score_gemma":0.0007714557,"teacher_disagreement_score":0.0007924009,"about_ca_system_score_codex":0.00017777566,"about_ca_system_score_gemma":0.00031835993,"threshold_uncertainty_score":0.0026509166},"labels":[],"label_agreement":null},{"id":"W1981195782","doi":"10.1172/jci43132","title":"Caught red-handed: uric acid is an agent of inflammation","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; National Institutes of Health; University of Calgary","keywords":"Endogeny; Inflammation; Uric acid; Pathogenesis; In vivo; Immunology; Inflammatory response; Chemistry; Biology; Biochemistry","score_opus":0.03697079814256333,"score_gpt":0.34030656719552277,"score_spread":0.30333576905295945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981195782","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022911312,0.3780315,0.0066610323,0.31147787,0.2593557,0.000059380705,0.00020757494,0.00046139816,0.020834217],"genre_scores_gemma":[0.16624992,0.24975842,0.0063309036,0.2139074,0.25886512,0.00006488173,0.00026025993,0.00029365317,0.1042695],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991885,0.0001752951,0.00007959525,0.00014880851,0.00033571754,0.000072164155],"domain_scores_gemma":[0.99891126,0.00034627467,0.00017738022,0.00014471941,0.00022103006,0.00019931226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009782694,0.000633946,0.0010249633,0.00073497446,0.00084564334,0.003949841,0.00084822095,0.0030206065,0.0042609265],"category_scores_gemma":[0.0020214403,0.00037686218,0.0005243444,0.0005266357,0.0029103612,0.003221008,0.0011468198,0.004919867,0.0019121006],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013911981,0.00016656885,0.005135815,0.0016931792,0.00037844302,0.0042491974,0.0009157829,0.00014263486,0.07289948,0.038892314,0.57282364,0.30131173],"study_design_scores_gemma":[0.00006517938,0.0002567651,0.0031035044,0.00026301912,0.000111158566,0.0051697777,0.00061188807,0.00016110146,0.014776418,0.014975306,0.9604592,0.000046680107],"about_ca_topic_score_codex":0.00026760602,"about_ca_topic_score_gemma":0.00055670907,"teacher_disagreement_score":0.0042609265,"about_ca_system_score_codex":0.00056997983,"about_ca_system_score_gemma":0.00044605657,"threshold_uncertainty_score":0.014254212},"labels":[],"label_agreement":null},{"id":"W1981374189","doi":"10.1172/jci35197","title":"Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":192,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"Zentrum für Regenerative Therapien Dresden; Ministero della Salute; Technische Universität Dresden","keywords":"Immunology; Autoimmunity; Transplantation; Immunosuppression; T cell; Autoimmune disease; Immune system; Medicine; Islet; Biology; Diabetes mellitus; Endocrinology; Internal medicine; Antibody","score_opus":0.021480517504402073,"score_gpt":0.2672143550368892,"score_spread":0.2457338375324871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981374189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931177,0.004296083,0.0007026178,0.00019231295,0.000030348105,0.000016823036,0.000034502507,0.000079360114,0.0015303389],"genre_scores_gemma":[0.9982607,0.00087679905,0.00036484707,0.00011901738,0.00006985417,0.000009285481,0.00007984674,0.0000064369333,0.00021329861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998869,0.000040585826,0.0000133339445,0.000017374661,0.000020044625,0.000021809508],"domain_scores_gemma":[0.9998073,0.000055469827,0.00005508484,0.000019685565,0.000014470721,0.00004806638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026609527,0.0003003485,0.00033299357,0.00030879639,0.00017462374,0.00029304353,0.000085969245,0.0002935642,0.0009868015],"category_scores_gemma":[0.0004338949,0.00008052436,0.00017842742,0.00026918747,0.00017902796,0.00018872923,0.00013577676,0.00045747074,0.00023694344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029454739,0.00067268516,0.39867982,0.00026277566,0.00012848746,0.0129678,0.00033762795,0.0002477341,0.44689152,0.000329286,0.0010380361,0.1354987],"study_design_scores_gemma":[0.00035506883,0.0072702565,0.80241555,0.00006525619,0.00033339948,0.0686784,0.0002899549,0.00095965044,0.109677844,0.0006008547,0.009332675,0.000021035356],"about_ca_topic_score_codex":0.00008903651,"about_ca_topic_score_gemma":0.000094766394,"teacher_disagreement_score":0.0009868015,"about_ca_system_score_codex":0.000104376835,"about_ca_system_score_gemma":0.00012379138,"threshold_uncertainty_score":0.0033012033},"labels":[],"label_agreement":null},{"id":"W1981458452","doi":"10.1172/jci37028","title":"The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":175,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Child Health and Human Development; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Pennsylvania","keywords":"PDX1; Progenitor cell; Endocrine system; Progenitor; Diabetes mellitus; Enteroendocrine cell; Biology; Pancreas; Gene; Endocrinology; Internal medicine; Stem cell; Cell biology; Medicine; Bioinformatics; Genetics; Hormone; Islet","score_opus":0.042307176337199805,"score_gpt":0.3184363473086463,"score_spread":0.27612917097144646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981458452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98704344,0.0015925277,0.0072269333,0.0002513463,0.000052908956,0.000054816755,0.0010050217,0.00045030806,0.0023226566],"genre_scores_gemma":[0.9759404,0.0014128651,0.006119028,0.00018009513,0.000026771508,0.00016876055,0.0016821439,0.00022759341,0.014242385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99971956,0.00002398759,0.000020800948,0.000111627625,0.00007055995,0.000053390104],"domain_scores_gemma":[0.999762,0.000022295195,0.00010395521,0.0000141188875,0.000013194835,0.00008440616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016224865,0.00067907135,0.00029744502,0.0007380965,0.00032346885,0.0004481846,0.00049852213,0.0005146406,0.002175939],"category_scores_gemma":[0.000119109754,0.00053988886,0.00023221652,0.00018327114,0.00052183546,0.00026057893,0.0004406865,0.0011020047,0.0005644573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019098913,0.000044413948,0.0006362437,0.000030926283,0.0000062465747,0.00009007202,0.000024970766,0.00011746295,0.99634403,0.00028964123,0.00007425596,0.002150773],"study_design_scores_gemma":[0.00019961075,0.00042905685,0.020187296,0.000041540505,0.00006311571,0.00076357083,0.00007244288,0.0029917094,0.9640275,0.00038293825,0.010826516,0.00001472269],"about_ca_topic_score_codex":0.00040541257,"about_ca_topic_score_gemma":0.0006825224,"teacher_disagreement_score":0.002175939,"about_ca_system_score_codex":0.00057429884,"about_ca_system_score_gemma":0.00029271207,"threshold_uncertainty_score":0.0072792172},"labels":[],"label_agreement":null},{"id":"W1981736657","doi":"10.1172/jci11941","title":"Somatostatin is required for masculinization of growth hormone–regulated hepatic gene expression but not of somatic growth","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health; Robert Wood Johnson Foundation","keywords":"Internal medicine; Endocrinology; Sexual dimorphism; Biology; Somatostatin; Ultradian rhythm; Hypothalamus; Prolactin; Hormone; Circadian rhythm; Medicine","score_opus":0.06850152190120001,"score_gpt":0.3390165227282402,"score_spread":0.27051500082704016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981736657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970931,0.00057961215,0.00065020827,0.0000634525,0.000020033582,0.000010149079,0.0003343672,0.000046264704,0.0012027483],"genre_scores_gemma":[0.99538654,0.0004316625,0.000797991,0.000041359235,0.000010976993,0.000021879734,0.000699354,0.000045778885,0.002564342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998772,0.000018958042,0.000014232756,0.000022135091,0.000035593315,0.000031875043],"domain_scores_gemma":[0.99971646,0.00002489492,0.00011534086,0.000022893957,0.000012605152,0.000107694934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009538034,0.00036293454,0.0002113813,0.00019185213,0.00011182709,0.00024198239,0.00012046732,0.00019236372,0.0027871404],"category_scores_gemma":[0.00015970666,0.00025290452,0.00018055784,0.000082106475,0.00028822065,0.00011808032,0.00020819948,0.00030951967,0.00075033936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018572468,0.000007534715,0.00046125805,0.000014185428,0.0000028570555,0.00018601751,0.0000058733385,0.000013244005,0.99834824,0.000052307274,0.000019634148,0.0007031008],"study_design_scores_gemma":[0.00008894611,0.00064334914,0.058548883,0.000013526437,0.000024846086,0.0033290635,0.000060692782,0.0004214582,0.933489,0.00008577226,0.0032844145,0.000009970231],"about_ca_topic_score_codex":0.00030721512,"about_ca_topic_score_gemma":0.00062362925,"teacher_disagreement_score":0.0027871404,"about_ca_system_score_codex":0.00015336997,"about_ca_system_score_gemma":0.0001564987,"threshold_uncertainty_score":0.009323895},"labels":[],"label_agreement":null},{"id":"W1982006510","doi":"10.1172/jci59110","title":"Anti-ganglioside antibody internalization attenuates motor nerve terminal injury in a mouse model of acute motor axonal neuropathy","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Peripheral Neuropathies and Disorders","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"University of Glasgow; Cancer Research UK","keywords":"Acute motor axonal neuropathy; Internalization; Endocytic cycle; Ganglioside; Endocytosis; Motor neuron; Neuroscience; Complement system; Cell biology; Endosome; Biology; Axoplasmic transport; Axon; Neuromuscular junction; Motor nerve; Immunology; Guillain-Barre syndrome; Medicine; Immune system; Biochemistry; Cell; Intracellular","score_opus":0.057008942601678596,"score_gpt":0.3723510009975372,"score_spread":0.3153420583958586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982006510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956715,0.0011749499,0.0014080608,0.00012748135,0.000072435454,0.00009327892,0.00024580173,0.00013843713,0.0010680996],"genre_scores_gemma":[0.99091864,0.0013792537,0.0018421662,0.000115676,0.000021606515,0.00018489962,0.0004770648,0.000028339055,0.0050324723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996425,0.000056391415,0.000040699222,0.00006105775,0.00007831779,0.00012096757],"domain_scores_gemma":[0.9998198,0.000012748964,0.00004964447,0.000018768576,0.000021737696,0.00007726729],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032376722,0.001034152,0.0006705866,0.00072530675,0.0002812591,0.00034212592,0.0005186385,0.0011794408,0.0013576386],"category_scores_gemma":[0.00014850944,0.00033242864,0.0004847525,0.00026228683,0.00047021083,0.00057250186,0.00028352469,0.0015035528,0.00039741633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012268309,0.00082017464,0.00028009925,0.00011626949,0.000016895592,0.00013984882,0.000051801097,0.000121758305,0.99521554,0.00011441636,0.00007796894,0.0018184122],"study_design_scores_gemma":[0.00025203484,0.011265162,0.010778986,0.00004849288,0.00010464776,0.0005190699,0.00012264318,0.0030444625,0.9714356,0.0001596883,0.0022484208,0.000020768837],"about_ca_topic_score_codex":0.0012403086,"about_ca_topic_score_gemma":0.0019436798,"teacher_disagreement_score":0.0013576386,"about_ca_system_score_codex":0.00051230134,"about_ca_system_score_gemma":0.00039535802,"threshold_uncertainty_score":0.0045417547},"labels":[],"label_agreement":null},{"id":"W1982761604","doi":"10.1172/jci24219","title":"Developmental control of CD8+ T cell–avidity maturation in autoimmune diabetes","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; National Institutes of Health; Canadian Diabetes Association","keywords":"Avidity; Autoimmunity; Immunology; Biology; T cell; T-cell receptor; CD8; Antigen; Central tolerance; Autoimmune disease; Population; Immune system; Medicine; Antibody","score_opus":0.01978630720306778,"score_gpt":0.29308075549969786,"score_spread":0.2732944482966301,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982761604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99632347,0.0014585557,0.0011957185,0.000039650356,0.000010968438,0.000012134634,0.00007678619,0.000043091928,0.00083971355],"genre_scores_gemma":[0.99718934,0.0006472576,0.0011887803,0.00004294042,0.000012928329,0.000019479257,0.00009242091,0.000017308035,0.0007894082],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99986887,0.00002625804,0.0000132838995,0.00003325674,0.000025813057,0.00003251229],"domain_scores_gemma":[0.9998574,0.000019230167,0.00004045556,0.000015479261,0.000020691705,0.000046706293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022420869,0.00018697571,0.00015968001,0.00025998187,0.00013402493,0.0003025113,0.00018897522,0.00022184706,0.0007525868],"category_scores_gemma":[0.00019003135,0.00015317865,0.00012310757,0.00011817483,0.0002049729,0.00018761861,0.00022202841,0.00049889815,0.00024280282],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015965496,0.000019595569,0.0014915088,0.000016866823,0.0000018647513,0.00004744102,0.00002040985,0.000041324292,0.9955857,0.00006495083,0.000014837002,0.0025357995],"study_design_scores_gemma":[0.00007114198,0.0011395214,0.13543922,0.00002328516,0.000033905693,0.0011138894,0.00014910412,0.0014619643,0.85640794,0.0004178701,0.0037257925,0.000016401213],"about_ca_topic_score_codex":0.00026803758,"about_ca_topic_score_gemma":0.00032272405,"teacher_disagreement_score":0.0007525868,"about_ca_system_score_codex":0.0002656603,"about_ca_system_score_gemma":0.00014196108,"threshold_uncertainty_score":0.0025177002},"labels":[],"label_agreement":null},{"id":"W1982797619","doi":"10.1172/jci32040","title":"Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Ligue Contre le Cancer","keywords":"Furin; Cancer research; Metastasis; Colorectal cancer; Cell culture; Proprotein Convertases; Biology; Cell migration; Medicine; Internal medicine; Endocrinology; Cancer; LDL receptor; Biochemistry","score_opus":0.052076592155756087,"score_gpt":0.32619882948594553,"score_spread":0.2741222373301894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982797619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993662,0.002158059,0.0014955667,0.00010450316,0.00003844581,0.00004964015,0.00035291215,0.00009567086,0.00204309],"genre_scores_gemma":[0.9930078,0.0015816183,0.0013429666,0.00004107007,0.000011109724,0.000047727153,0.0006853373,0.000015586033,0.0032668046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998771,0.00002257162,0.0000123430345,0.000019528166,0.000034545035,0.00003381554],"domain_scores_gemma":[0.9999291,0.00001899167,0.0000143922,0.000010828829,0.000008807622,0.00001780421],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014142228,0.00032204756,0.00032641587,0.0001557719,0.000114385926,0.00031712127,0.00015469226,0.00014106739,0.0010019372],"category_scores_gemma":[0.000097321674,0.00011138108,0.00015180517,0.00014896215,0.00016270895,0.00008154514,0.000109666384,0.00044698577,0.0003679612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002001886,0.00010527881,0.00010672154,0.000035914778,0.0000057875186,0.00003665105,0.000013919663,0.00006750115,0.9973476,0.00008639459,0.00010611758,0.0018878899],"study_design_scores_gemma":[0.000049079317,0.00073374563,0.0027966313,0.00000449933,0.000016001348,0.00013615083,0.000018768586,0.0012616728,0.99207944,0.000021603582,0.0028794575,0.0000030159779],"about_ca_topic_score_codex":0.0010974722,"about_ca_topic_score_gemma":0.0019054109,"teacher_disagreement_score":0.0010974722,"about_ca_system_score_codex":0.0002691387,"about_ca_system_score_gemma":0.00029737412,"threshold_uncertainty_score":0.003351748},"labels":[],"label_agreement":null},{"id":"W1982999222","doi":"10.1172/jci78371","title":"Glucagon-like peptide-1 receptors in the brain: controlling food intake and body weight","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Banting and Best Diabetes Centre, University of Toronto; Novo Nordisk","keywords":"Endocrinology; Agonist; Glucagon-like peptide-1; Internal medicine; Weight loss; Receptor; Glucagon; Glucagon-like peptide 1 receptor; Insulin; Diabetes mellitus; Chemistry; Gastric emptying; Hormone; Biology; Obesity; Medicine; Type 2 diabetes","score_opus":0.04995993102065931,"score_gpt":0.32967399250644447,"score_spread":0.27971406148578515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982999222","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23618622,0.6922975,0.010116063,0.02521645,0.0018168906,0.000049267772,0.00024400203,0.00032939584,0.033744242],"genre_scores_gemma":[0.64932853,0.32562068,0.008037026,0.00497269,0.0023161087,0.000058810263,0.00016471314,0.000033931206,0.00946747],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999329,0.000011208903,0.0000036029255,0.00001307647,0.000023699484,0.000015554333],"domain_scores_gemma":[0.9999528,0.000004936507,0.000009242341,0.0000023923349,0.00000943193,0.000021191185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021707409,0.0002802671,0.00031861375,0.0004174996,0.0001945013,0.0008526386,0.0003317799,0.00047783632,0.00094991195],"category_scores_gemma":[0.00015650722,0.00010377324,0.00013262028,0.0002789305,0.0007675926,0.00081748277,0.00033188052,0.0009929995,0.00030257102],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017422746,0.00030812746,0.0034428118,0.0017035485,0.000058960966,0.0021859293,0.00034827483,0.0006301459,0.27725273,0.019665848,0.0133312605,0.67933017],"study_design_scores_gemma":[0.00083444116,0.0041041584,0.1953541,0.0017099568,0.0005039461,0.018336248,0.0026910787,0.0048622577,0.20967093,0.10800439,0.45360455,0.00032394688],"about_ca_topic_score_codex":0.0006073939,"about_ca_topic_score_gemma":0.0008030357,"teacher_disagreement_score":0.00094991195,"about_ca_system_score_codex":0.00046297922,"about_ca_system_score_gemma":0.00041336773,"threshold_uncertainty_score":0.003359139},"labels":[],"label_agreement":null},{"id":"W1983062261","doi":"10.1172/jci12346","title":"Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":242,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Health Research Institutes; National Institutes of Health; University of Alberta; Alexander and Margaret Stewart Trust","keywords":"Calreticulin; DNA vaccination; Antigen; Cancer research; Immunotherapy; Immunology; Biology; CD8; Medicine; Immune system","score_opus":0.05023108018379265,"score_gpt":0.3201335877642197,"score_spread":0.26990250758042705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983062261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989408,0.002352633,0.0055302223,0.00016547828,0.000065292545,0.00017145886,0.000141325,0.000089303576,0.002076195],"genre_scores_gemma":[0.9934396,0.0007559401,0.0043158107,0.00008428542,0.000022536798,0.00008737699,0.00022482585,0.0000105184945,0.0010592488],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997086,0.00007337972,0.000020764013,0.000053855183,0.00006766642,0.00007574552],"domain_scores_gemma":[0.999884,0.000024371973,0.000037664227,0.000014445686,0.000010366311,0.000029086708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025806227,0.00047471467,0.00033256432,0.00027885602,0.00008739743,0.00024781862,0.00019436302,0.00067104434,0.0009794777],"category_scores_gemma":[0.00018040827,0.00014759465,0.00031543418,0.00013116731,0.0003560708,0.00026864826,0.00023289435,0.0010793328,0.0002173087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023733555,0.00024840268,0.00022886085,0.00007167429,0.000008581197,0.000049760238,0.0000114225995,0.0001927558,0.99457353,0.00021716788,0.00004212132,0.004118423],"study_design_scores_gemma":[0.00017819412,0.003925243,0.0037839971,0.000012503402,0.00003541223,0.00062133255,0.000017090744,0.0019707135,0.9867138,0.00010135055,0.0026351702,0.0000051698466],"about_ca_topic_score_codex":0.00012749911,"about_ca_topic_score_gemma":0.0002524244,"teacher_disagreement_score":0.0009794777,"about_ca_system_score_codex":0.00023492472,"about_ca_system_score_gemma":0.00027922186,"threshold_uncertainty_score":0.0032767057},"labels":[],"label_agreement":null},{"id":"W1983588069","doi":"10.1172/jci69346","title":"Leptin and the brain: then and now","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of Washington; Office of Research and Development; U.S. Department of Veterans Affairs","keywords":"Leptin; Leptin receptor; Hormone; Obesity; Adipocyte; Endocrinology; Internal medicine; Insulin; Receptor; Medicine; Mutation; Biology; Neuroscience; Bioinformatics; Gene; Adipose tissue; Genetics","score_opus":0.08887928637240049,"score_gpt":0.3512826152669539,"score_spread":0.2624033288945534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983588069","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00424376,0.9205406,0.0008177659,0.06284669,0.0028078966,0.000004251533,0.000027921684,0.000031473654,0.008679656],"genre_scores_gemma":[0.10008947,0.8393691,0.0021941087,0.030252064,0.0076387418,0.000042682866,0.00007849795,0.000020421421,0.020314813],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996263,0.00010762978,0.000026315134,0.00007530735,0.00008415737,0.000080317],"domain_scores_gemma":[0.999676,0.000088809276,0.00003283716,0.000032922922,0.00009401497,0.00007541575],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011440619,0.0004996246,0.0006179022,0.0006967557,0.0011746242,0.0038339181,0.0005154106,0.0030133186,0.003498654],"category_scores_gemma":[0.0007296945,0.00014178171,0.00033383304,0.00074461306,0.0056093154,0.010416191,0.0018007271,0.0035391757,0.0007845175],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009576295,0.0002237247,0.0040312097,0.002109301,0.00013895641,0.0015258475,0.0036526283,0.00035653927,0.022357117,0.298656,0.08254407,0.5834469],"study_design_scores_gemma":[0.00003078997,0.00015124299,0.0032450012,0.0010884952,0.000034367076,0.0011472306,0.0039316225,0.00007802409,0.0010047815,0.12725723,0.8619869,0.000044492164],"about_ca_topic_score_codex":0.0030745687,"about_ca_topic_score_gemma":0.00492988,"teacher_disagreement_score":0.0038339181,"about_ca_system_score_codex":0.001790593,"about_ca_system_score_gemma":0.0018159576,"threshold_uncertainty_score":0.012991786},"labels":[],"label_agreement":null},{"id":"W1985475058","doi":"10.1172/jci17490","title":"The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":575,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsches Krebsforschungszentrum; U.S. Public Health Service; Amgen","keywords":"Leptin; Endocrinology; Internal medicine; Hypothalamic–pituitary–thyroid axis; Starvation; Hormone; Medicine; Leptin receptor; Hypothalamus; Appetite; Obesity; Adipokine; Biology; Thyroid hormones","score_opus":0.14638553663737336,"score_gpt":0.3830263003065387,"score_spread":0.23664076366916537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985475058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99932194,0.0004564797,0.000060987597,0.000018572959,0.000005964096,0.000004268469,0.000023669401,0.0000021251344,0.00010602337],"genre_scores_gemma":[0.99956733,0.00009776616,0.00007852923,0.000024993064,0.000007729763,0.0000049715427,0.000038266033,0.0000010195014,0.00017935332],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998609,0.000044242803,0.0000137936495,0.000028596265,0.000021527863,0.000030803443],"domain_scores_gemma":[0.9996934,0.000056581866,0.000078966026,0.00002357264,0.000024112785,0.0001234281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032128062,0.00024016587,0.0003751338,0.00041275442,0.00040674716,0.00031911017,0.00012735026,0.0003665586,0.0007464287],"category_scores_gemma":[0.0009527844,0.00025820575,0.0001902063,0.00020425337,0.00043604997,0.00024323586,0.00020236372,0.0002752634,0.00009910518],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.023078043,0.0005837104,0.86033857,0.00013195233,0.00019578119,0.0022269601,0.000887384,0.00042992187,0.08025709,0.00012848587,0.00016805377,0.031574067],"study_design_scores_gemma":[0.0000731624,0.0037617325,0.99291384,0.0000044706067,0.00005065173,0.0009132031,0.00017617473,0.00012618721,0.0016622127,0.000053698797,0.00025572718,0.000008889039],"about_ca_topic_score_codex":0.0018774789,"about_ca_topic_score_gemma":0.00238394,"teacher_disagreement_score":0.0018774789,"about_ca_system_score_codex":0.0001953358,"about_ca_system_score_gemma":0.00017482933,"threshold_uncertainty_score":0.0037330985},"labels":[],"label_agreement":null},{"id":"W1986038834","doi":"10.1172/jci18397","title":"Salt-sensitive hypertension: if only it were as simple as rocket science","year":2003,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Sodium Intake and Health","field":"Nursing","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Salt (chemistry); Rocket (weapon); Reading (process); Population; Medicine; Psychology; History; Aeronautics; Political science; Chemistry; Environmental health; Engineering; Law","score_opus":0.13466247582160018,"score_gpt":0.4164070005046438,"score_spread":0.2817445246830436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986038834","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00033027292,0.0011788047,0.000053495383,0.9879901,0.009212065,0.000005411278,0.000015153888,0.000013683674,0.0012010484],"genre_scores_gemma":[0.0033190474,0.0015946018,0.00024853228,0.96583444,0.023882901,0.00002886033,0.00001241819,0.000015491461,0.0050636823],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976373,0.00082323514,0.0003482315,0.0003117436,0.00062850886,0.0002510529],"domain_scores_gemma":[0.99334323,0.003478267,0.00039521465,0.00021399767,0.0014870911,0.0010821624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0032280688,0.00078886026,0.0014316331,0.00058246375,0.0036452003,0.0026713174,0.0017962517,0.037571616,0.006043058],"category_scores_gemma":[0.020616487,0.00060377753,0.0011570244,0.00073272956,0.0028608919,0.005585918,0.0010634181,0.04343572,0.0063295187],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008021201,0.00006516534,0.0010642741,0.000064651445,0.000013635295,0.0022810642,0.00032594858,0.000040904186,0.00019731843,0.0017942883,0.9799436,0.014128933],"study_design_scores_gemma":[0.00022499295,0.00022886411,0.0033441249,0.00079407694,0.00006171007,0.009085745,0.001994279,0.00062119734,0.00032227923,0.01209604,0.9711303,0.000096391464],"about_ca_topic_score_codex":0.010666807,"about_ca_topic_score_gemma":0.016629063,"teacher_disagreement_score":0.037571616,"about_ca_system_score_codex":0.005328618,"about_ca_system_score_gemma":0.00344031,"threshold_uncertainty_score":0.038661957},"labels":[],"label_agreement":null},{"id":"W1986580482","doi":"10.1172/jci33612","title":"Building bone to reverse osteoporosis and repair fractures","year":2008,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":349,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute on Aging; National Institutes of Health","keywords":"Osteoporosis; Medicine; Bone healing; Anabolic Agents; Bone morphogenetic protein; Bone morphogenetic protein 7; Teriparatide; Bone morphogenetic protein 2; Anabolism; Bone Density Conservation Agents; Bone remodeling; Bioinformatics; Surgery; Bone mineral; Internal medicine; Biology","score_opus":0.07243970498226485,"score_gpt":0.41710231253691926,"score_spread":0.3446626075546544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986580482","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00037550833,0.99162966,0.00080169697,0.0011713699,0.0008278728,0.000015371223,0.000020598412,0.000035740868,0.0051221824],"genre_scores_gemma":[0.0018967123,0.9922197,0.0009174627,0.00060201477,0.000348207,0.000016499704,0.000026810309,0.0000049971236,0.003967669],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99986243,0.000021978225,0.000011862468,0.000019974714,0.000069971655,0.000013735361],"domain_scores_gemma":[0.9998913,0.000041804633,0.000014974948,0.0000070773826,0.000030126286,0.000014651565],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040112907,0.0006560629,0.00078383007,0.0018292764,0.00031154265,0.0007098466,0.0006789018,0.0012979513,0.004933271],"category_scores_gemma":[0.00039433816,0.00021017026,0.00028748516,0.0009783072,0.00076061767,0.001060104,0.0006204897,0.0016170602,0.004324637],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006015083,0.00011160117,0.00013065555,0.0041873297,0.000044978173,0.00027101854,0.00008397933,0.00032120224,0.0072533204,0.013840043,0.0445811,0.92911464],"study_design_scores_gemma":[0.000024087229,0.000050885646,0.00026595534,0.00051570265,0.000016296028,0.0009854793,0.000041586944,0.000054121174,0.0011575341,0.0032969043,0.99358386,0.000007634067],"about_ca_topic_score_codex":0.0007753666,"about_ca_topic_score_gemma":0.0016352136,"teacher_disagreement_score":0.004933271,"about_ca_system_score_codex":0.00043664913,"about_ca_system_score_gemma":0.00060197164,"threshold_uncertainty_score":0.016503453},"labels":[],"label_agreement":null},{"id":"W1986774614","doi":"10.1172/jci46322","title":"Angiopoietin-1 is essential in mouse vasculature during development and in response to injury","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":449,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Toronto Centre for Phenogenomics; St. Michael's Hospital; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; Synchrotron Light Research Institute; Wenner-Gren Foundation","keywords":"Angiopoietin receptor; Knockout mouse; Pericyte; Angiogenesis; Angiopoietin; Phenotype; Conditional gene knockout; Biology; Cell biology; Gene knockout; Fibrosis; Gene targeting; Immunology; Cancer research; Pathology; Gene; Medicine; Endothelial stem cell; Genetics; Vascular endothelial growth factor; In vitro","score_opus":0.05535281909641087,"score_gpt":0.34858220597395406,"score_spread":0.2932293868775432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986774614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98006743,0.0049470738,0.009359808,0.00035724865,0.000069028785,0.00007732811,0.0017280616,0.00043788995,0.0029561238],"genre_scores_gemma":[0.9819695,0.0020321775,0.005827149,0.000099515266,0.000020881209,0.000116622075,0.0015454211,0.00013159764,0.008257132],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996947,0.00004655924,0.000029774446,0.00006299651,0.000110212175,0.000055714652],"domain_scores_gemma":[0.9995695,0.000046660927,0.00015730232,0.0000541973,0.000030237808,0.0001421619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002829371,0.00034227403,0.00024872358,0.00067568023,0.0003019051,0.00056699,0.0003268939,0.0005076622,0.0016970322],"category_scores_gemma":[0.0002841395,0.00041951632,0.0001920216,0.00027677152,0.0004578509,0.0003742351,0.00030705816,0.0010831559,0.00085462857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012918758,0.00002190452,0.00033826413,0.000025399464,0.000002342227,0.00013332732,0.000020207332,0.000057238794,0.99723864,0.00026433982,0.000057570494,0.0017114843],"study_design_scores_gemma":[0.000048125996,0.00027146479,0.015649682,0.000022656384,0.000025189454,0.0013362188,0.000041801824,0.00087773555,0.9684031,0.00029333064,0.013021323,0.000009361056],"about_ca_topic_score_codex":0.00031591032,"about_ca_topic_score_gemma":0.00057314744,"teacher_disagreement_score":0.0016970322,"about_ca_system_score_codex":0.0004196155,"about_ca_system_score_gemma":0.00030132424,"threshold_uncertainty_score":0.0056771636},"labels":[],"label_agreement":null},{"id":"W1987191514","doi":"10.1172/jci57850","title":"The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; McMaster University; Canadian Blood Services; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; Canadian Blood Services; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Antibody; Platelet; Immunology; Immune system; Medicine; Fetus; Miscarriage; Biology; Pregnancy","score_opus":0.06504925598589575,"score_gpt":0.3337675421817897,"score_spread":0.268718286195894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987191514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9791053,0.0047528455,0.009923802,0.0008951533,0.00018705598,0.00013962176,0.0015370637,0.00080546783,0.0026536915],"genre_scores_gemma":[0.9780211,0.0037513904,0.006176568,0.00056990114,0.000099097364,0.00041645562,0.0014812323,0.00026074366,0.009223532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988004,0.00023096573,0.00015911585,0.0003429542,0.00023933638,0.00022733616],"domain_scores_gemma":[0.99876094,0.00017687754,0.000562372,0.00014661718,0.000046039375,0.00030720516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007041536,0.0011404711,0.00063804054,0.0021490045,0.00042488458,0.00064168114,0.000878735,0.0016477659,0.0024917035],"category_scores_gemma":[0.00067525246,0.0007661913,0.0010211047,0.0003823156,0.00084909395,0.00055652764,0.0006248284,0.002389575,0.0007613907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011076719,0.0003213132,0.0008871589,0.0001114085,0.00005450587,0.0007047771,0.00013746254,0.00019697193,0.9924247,0.00067347154,0.00023196374,0.0031485874],"study_design_scores_gemma":[0.0002819182,0.003797782,0.013346345,0.000101867176,0.00018030708,0.0046392353,0.00022144985,0.0037049518,0.9654246,0.00057696557,0.0076748184,0.000049650123],"about_ca_topic_score_codex":0.000941752,"about_ca_topic_score_gemma":0.0012065667,"teacher_disagreement_score":0.0024917035,"about_ca_system_score_codex":0.00072179764,"about_ca_system_score_gemma":0.000410736,"threshold_uncertainty_score":0.00833559},"labels":[],"label_agreement":null},{"id":"W1989188472","doi":"10.1172/jci43615","title":"Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Glucagon receptor; Internal medicine; Endocrinology; Incretin; Glucose homeostasis; Glucagon; Receptor; Glucagon-like peptide 1 receptor; Biology; Glucagon-like peptide-1; Agonist; Insulin; Type 2 diabetes; Diabetes mellitus; Insulin resistance; Medicine","score_opus":0.0892509425484842,"score_gpt":0.3407440297576234,"score_spread":0.2514930872091392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989188472","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756586,0.0023666641,0.013367037,0.0009835858,0.00025074993,0.00018830482,0.0030669698,0.0011776518,0.0029405407],"genre_scores_gemma":[0.95290387,0.0036951983,0.0257678,0.00093821035,0.00015605018,0.00058584125,0.0033566097,0.0011792325,0.011417241],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990319,0.00012855964,0.00014987834,0.00029437922,0.00020567492,0.00018965812],"domain_scores_gemma":[0.99916196,0.00009485385,0.00030907325,0.00011507774,0.00004233615,0.00027670056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051686115,0.0012007338,0.0007523391,0.0016653666,0.0004672581,0.0011810918,0.0010220376,0.0013362628,0.0031746242],"category_scores_gemma":[0.00035629523,0.0009823799,0.0010148856,0.00053419435,0.0011394026,0.0008307121,0.00074242085,0.0037740148,0.0011569264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051306817,0.000121195866,0.0001975168,0.000043562242,0.000018564075,0.00013763382,0.000036304536,0.00008838335,0.9967334,0.0004026143,0.00009987314,0.0016079826],"study_design_scores_gemma":[0.0004925213,0.001939298,0.0103135845,0.00009964877,0.00018216185,0.0025679017,0.0001911922,0.0021933708,0.9721148,0.00082558574,0.009011991,0.00006791853],"about_ca_topic_score_codex":0.00054796116,"about_ca_topic_score_gemma":0.0012835701,"teacher_disagreement_score":0.0031746242,"about_ca_system_score_codex":0.00063196523,"about_ca_system_score_gemma":0.00042947347,"threshold_uncertainty_score":0.010620177},"labels":[],"label_agreement":null},{"id":"W1989273697","doi":"10.1172/jci32103","title":"Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":835,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; School of Medicine, Stanford University; National Heart, Lung, and Blood Institute; School of Medicine, Oregon Health and Science University; National Cancer Institute; National Institutes of Health; National Center for Research Resources; Cancer Research Institute","keywords":"Adoptive cell transfer; Cytotoxic T cell; Biology; CD8; Effector; Immunology; T cell; Immunotherapy; Antigen; Cell biology; Immune system; In vitro; Genetics","score_opus":0.07917265780015434,"score_gpt":0.3354791466112934,"score_spread":0.25630648881113904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989273697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97847855,0.0036406976,0.009754099,0.00017827736,0.00005068616,0.00025279258,0.00028131533,0.0004153759,0.0069481744],"genre_scores_gemma":[0.98848236,0.0014239431,0.004903432,0.00018334297,0.000049148086,0.00027821196,0.000578579,0.00009474689,0.0040063336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975616,0.00004994841,0.000016055224,0.000071273345,0.000045634777,0.00006090161],"domain_scores_gemma":[0.99976045,0.00004220549,0.000040959625,0.0000869851,0.000028028555,0.000041310966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042948985,0.00042306908,0.00035920477,0.0005848957,0.0005870761,0.00059383974,0.00039482996,0.0004556172,0.0018402982],"category_scores_gemma":[0.00045952047,0.00027994957,0.00019296848,0.0001983725,0.0005313896,0.00030742638,0.00032729743,0.0011675952,0.0007054214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004774024,0.00029548464,0.0011758874,0.00006777641,0.000018623003,0.0003592419,0.00028157557,0.00014119971,0.9800284,0.0006529295,0.0003346977,0.016166912],"study_design_scores_gemma":[0.00061022333,0.00534559,0.014426242,0.00014521717,0.0001688309,0.0060637454,0.0003326036,0.002870362,0.9279571,0.0028458987,0.039204605,0.000029687471],"about_ca_topic_score_codex":0.0005058554,"about_ca_topic_score_gemma":0.00062195037,"teacher_disagreement_score":0.0018402982,"about_ca_system_score_codex":0.00031307276,"about_ca_system_score_gemma":0.00022581709,"threshold_uncertainty_score":0.006156385},"labels":[],"label_agreement":null},{"id":"W1989532668","doi":"10.1172/jci10720","title":"The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"Medical Research Council; Deutsche Forschungsgemeinschaft; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"DDR1; Discoidin domain; Neointima; Receptor tyrosine kinase; Vascular smooth muscle; Cell biology; Biology; Receptor; Tyrosine kinase; Kinase; Signal transduction; Endocrinology; Internal medicine; Medicine; Biochemistry; Smooth muscle","score_opus":0.09035967827613907,"score_gpt":0.4106547178515482,"score_spread":0.32029503957540917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989532668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7782748,0.20537789,0.0047278972,0.0036337231,0.00028284598,0.00003304183,0.00015072564,0.000041089625,0.007477991],"genre_scores_gemma":[0.955672,0.038509168,0.0013416022,0.0001954008,0.00013140675,0.00001685478,0.00011662463,0.0000036150907,0.0040132967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985874,0.00004118415,0.000011941972,0.000015001361,0.000031236494,0.000041921845],"domain_scores_gemma":[0.99989545,0.00002297122,0.000028138542,0.000006002605,0.000012507901,0.000034903616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042248028,0.00037309606,0.00030601397,0.00030953446,0.00023622204,0.0005298556,0.00016841012,0.0005831014,0.0010743205],"category_scores_gemma":[0.00024940533,0.00012545481,0.00014145639,0.00015278772,0.0004287084,0.000361062,0.00024037708,0.0005970806,0.00031636845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034694304,0.0003322736,0.0095272735,0.0012699717,0.000055867215,0.0031484528,0.00027642,0.0012145512,0.84087765,0.009774081,0.0027315547,0.1273225],"study_design_scores_gemma":[0.0007857018,0.0030384911,0.15047406,0.0003798583,0.00034027817,0.01792239,0.0010302612,0.0061181067,0.7080184,0.010593721,0.10122889,0.00006981771],"about_ca_topic_score_codex":0.00037068722,"about_ca_topic_score_gemma":0.0004969154,"teacher_disagreement_score":0.0010743205,"about_ca_system_score_codex":0.0005316817,"about_ca_system_score_gemma":0.00029645584,"threshold_uncertainty_score":0.0038576722},"labels":[],"label_agreement":null},{"id":"W1990375242","doi":"10.1172/jci9871","title":"Reovirus as a novel oncolytic agent","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada; Fondation pour la Recherche Médicale","keywords":"Oncolytic virus; Biology; Carcinogenesis; Cancer cell; Virology; Cancer; In vivo; In vitro; Cancer research; Virus; Genetics","score_opus":0.10689183105527948,"score_gpt":0.4309146649130977,"score_spread":0.3240228338578182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990375242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60733396,0.1641585,0.1498026,0.0028725532,0.0037575006,0.00085709326,0.0011685557,0.0026030077,0.06744622],"genre_scores_gemma":[0.87839097,0.04147949,0.043958426,0.000655197,0.00039102952,0.00023439643,0.0009068207,0.0001458449,0.0338379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998907,0.0000142484305,0.00000447957,0.000024553054,0.00003946703,0.000026543776],"domain_scores_gemma":[0.9999558,0.0000059477484,0.0000065569025,0.000005880395,0.0000076537135,0.000018160525],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015840781,0.00047845393,0.00032199814,0.00037731908,0.00023836893,0.0005707725,0.0004299429,0.0006218922,0.001004081],"category_scores_gemma":[0.000100795565,0.00014311774,0.00033009637,0.0001613526,0.00027517337,0.0004907958,0.00033105005,0.00086246233,0.00076351967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000355785,0.00021527856,0.0002101445,0.00020715679,0.000019942174,0.00046747213,0.000050298022,0.00065219414,0.93934244,0.00748769,0.0014525506,0.049538974],"study_design_scores_gemma":[0.00015119908,0.0013875186,0.0005949936,0.000041723666,0.000060140435,0.002042222,0.000012896502,0.00201065,0.8546915,0.0009903862,0.13799095,0.00002586983],"about_ca_topic_score_codex":0.0005146296,"about_ca_topic_score_gemma":0.00065873197,"teacher_disagreement_score":0.001004081,"about_ca_system_score_codex":0.00048590466,"about_ca_system_score_gemma":0.00027693625,"threshold_uncertainty_score":0.0035255551},"labels":[],"label_agreement":null},{"id":"W1990406538","doi":"10.1172/jci40839","title":"Pathogenic antibodies are active participants in spinal cord injury","year":2009,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Neuroprotection; Pathogenesis; Autoimmunity; Spinal cord injury; Medicine; Antibody; Spinal cord; Immunology; Lesion; Disease; Mechanism (biology); Neuroscience; Bioinformatics; Pathology; Biology; Internal medicine","score_opus":0.25220949279824617,"score_gpt":0.43146206431941914,"score_spread":0.17925257152117297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990406538","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.069973476,0.020175388,0.0014257948,0.8572697,0.012922516,0.00010860254,0.00014579308,0.00027452668,0.03770427],"genre_scores_gemma":[0.41293797,0.021291556,0.0015200195,0.46781787,0.07737586,0.00012531313,0.00011513887,0.00006130506,0.018755037],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992329,0.00027513396,0.000073635245,0.00010096219,0.00021681648,0.0001006605],"domain_scores_gemma":[0.9984864,0.00090236735,0.00018437237,0.00008675545,0.00022571921,0.000114357295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010727814,0.0005728318,0.0008469655,0.00046351572,0.0015241767,0.0011820062,0.0005452649,0.012823254,0.002566946],"category_scores_gemma":[0.0054176603,0.00026168785,0.0003862891,0.00044801828,0.0012287064,0.0014217326,0.00047465813,0.0052193333,0.0015751603],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019267738,0.00048167576,0.03291301,0.00079007325,0.00011862796,0.17446269,0.0013481717,0.0003260787,0.014323235,0.013924535,0.59724694,0.1621382],"study_design_scores_gemma":[0.0010942079,0.001273683,0.04414891,0.0010038841,0.00025260146,0.21129148,0.0014055267,0.002349077,0.0047745793,0.035895728,0.69637877,0.00013151215],"about_ca_topic_score_codex":0.00084301014,"about_ca_topic_score_gemma":0.0011554274,"teacher_disagreement_score":0.012823254,"about_ca_system_score_codex":0.0009964453,"about_ca_system_score_gemma":0.00040908734,"threshold_uncertainty_score":0.008587241},"labels":[],"label_agreement":null},{"id":"W1990714106","doi":"10.1172/jci41681","title":"LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; Welch Foundation; University of Toronto; Howard Hughes Medical Institute","keywords":"Liver X receptor; Glucocorticoid receptor; Endocrinology; Glucocorticoid; Internal medicine; Dexamethasone; Hyperinsulinemia; Steatosis; Transactivation; Biology; Nuclear receptor; Insulin resistance; Diabetes mellitus; Medicine; Gene expression; Transcription factor; Biochemistry","score_opus":0.09108783566632311,"score_gpt":0.39048727659482624,"score_spread":0.2993994409285031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990714106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9765355,0.0029359339,0.010639832,0.0009868339,0.00013512053,0.00011447556,0.004121883,0.00078092545,0.003749411],"genre_scores_gemma":[0.97754043,0.002272899,0.0065804934,0.0004200659,0.000058281257,0.00022788547,0.0033554113,0.00043269858,0.00911183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994307,0.00009869873,0.000081937265,0.00013207892,0.00015382945,0.0001026601],"domain_scores_gemma":[0.9991704,0.000080605656,0.00037640313,0.00008852039,0.000041486535,0.00024263622],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004084952,0.00088856067,0.0005003325,0.0012878506,0.00037869133,0.00094199023,0.0004481009,0.0007570022,0.0046030176],"category_scores_gemma":[0.0003028039,0.0007788393,0.00060035783,0.00040342848,0.00078474486,0.00029395212,0.00040883935,0.0015054409,0.0017226934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036060397,0.000052930463,0.00036806377,0.000031188643,0.000015555635,0.00021450518,0.000032987922,0.00006891133,0.9973917,0.00030591307,0.000112980364,0.0010445985],"study_design_scores_gemma":[0.00036368592,0.00054958975,0.013500239,0.00007459579,0.00009493795,0.0032894663,0.00019114433,0.0016133495,0.96923804,0.0006064184,0.010445944,0.000032514294],"about_ca_topic_score_codex":0.0010270097,"about_ca_topic_score_gemma":0.0014110706,"teacher_disagreement_score":0.0046030176,"about_ca_system_score_codex":0.0005381282,"about_ca_system_score_gemma":0.0005158851,"threshold_uncertainty_score":0.015398681},"labels":[],"label_agreement":null},{"id":"W1990753699","doi":"10.1172/jci40794","title":"Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Centre National de la Recherche Scientifique; Université de Strasbourg; Institute of Genetics; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; European Commission","keywords":"Enteroendocrine cell; Homeostasis; Endocrinology; Biology; Internal medicine; Hormone; Intestinal epithelium; Energy homeostasis; Glucose homeostasis; Endocrine system; Epithelium; Cell biology; Insulin; Medicine; Insulin resistance","score_opus":0.034018396515408736,"score_gpt":0.3292134940903333,"score_spread":0.29519509757492457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990753699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899018,0.0017135491,0.0049649696,0.00022144352,0.00005987731,0.00004733597,0.0014248255,0.0005133992,0.001152868],"genre_scores_gemma":[0.9789752,0.0025840923,0.007261691,0.00021944578,0.00003077627,0.00018232017,0.0021365862,0.00036902976,0.008240805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943465,0.000052896226,0.00009188923,0.00017231697,0.00012390476,0.00012435518],"domain_scores_gemma":[0.999071,0.000107177904,0.00037749187,0.00007621768,0.00004855264,0.00031940854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031540802,0.0011485612,0.0005594522,0.0014244452,0.0003098362,0.00071291294,0.00073523895,0.0010500591,0.0019943984],"category_scores_gemma":[0.00033122336,0.0006167831,0.0005878379,0.0003474932,0.00073550694,0.00055924326,0.0005517693,0.0015666584,0.00069409877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040862168,0.00007536241,0.00071511616,0.00004403596,0.000015100191,0.00030672605,0.000041488336,0.00017047685,0.99593264,0.00018091747,0.00006787654,0.002041677],"study_design_scores_gemma":[0.0001679838,0.00091385056,0.031160874,0.00008538462,0.00013344987,0.0023916706,0.0002106115,0.0026108527,0.9567515,0.0004229674,0.0051039685,0.000046743517],"about_ca_topic_score_codex":0.00087266683,"about_ca_topic_score_gemma":0.0014799788,"teacher_disagreement_score":0.0019943984,"about_ca_system_score_codex":0.00059009984,"about_ca_system_score_gemma":0.00041891067,"threshold_uncertainty_score":0.006671965},"labels":[],"label_agreement":null},{"id":"W1991680301","doi":"10.1172/jci40256","title":"Genomic amplicons target vesicle recycling in breast cancer","year":2009,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"University of Texas MD Anderson Cancer Center; National Cancer Institute; Genome Canada","keywords":"Rab; Amplicon; Biology; Cancer research; Breast cancer; Carcinogenesis; Cancer; Endocytosis; GTPase; Metastasis; Cell biology; Bioinformatics; Genetics; Receptor; Gene","score_opus":0.12428894540841819,"score_gpt":0.4300942375831218,"score_spread":0.30580529217470365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991680301","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03467838,0.021527816,0.0021501721,0.8837787,0.019510657,0.00009494752,0.000098846904,0.00032313436,0.03783738],"genre_scores_gemma":[0.30641347,0.031528443,0.0023911959,0.52316064,0.10466757,0.00015727502,0.00015735994,0.00009046423,0.031433597],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99958414,0.00013548702,0.000039752627,0.00004208797,0.00013371522,0.00006482075],"domain_scores_gemma":[0.99930465,0.00044222936,0.000052158488,0.000037198002,0.00009032028,0.000073422445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061732094,0.00040995888,0.00048335487,0.0003059139,0.00066803413,0.0006127195,0.0005936875,0.008740954,0.002359427],"category_scores_gemma":[0.0022572167,0.00023711925,0.00038209022,0.00025454612,0.0007317052,0.0006022749,0.0003615477,0.004292936,0.0016164574],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067427236,0.00022550656,0.0061947214,0.0003521353,0.000059551272,0.066531494,0.00018743261,0.0007647801,0.0156692,0.012582995,0.77103466,0.1257232],"study_design_scores_gemma":[0.0005716928,0.0007964192,0.010207386,0.00038455118,0.00013296554,0.110233,0.00037211814,0.004446232,0.015189646,0.023308355,0.834291,0.00006662161],"about_ca_topic_score_codex":0.00044634496,"about_ca_topic_score_gemma":0.0010596163,"teacher_disagreement_score":0.008740954,"about_ca_system_score_codex":0.001556487,"about_ca_system_score_gemma":0.00033019017,"threshold_uncertainty_score":0.011293173},"labels":[],"label_agreement":null},{"id":"W1992901332","doi":"10.1172/jci28377","title":"Twenty-first century plague The story of SARS","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"History of Science and Medicine","field":"Arts and Humanities","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Plague (disease); Virology; Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Pandemic; History; Biology; Medicine; Ancient history; Outbreak; Infectious disease (medical specialty); Pathology","score_opus":0.1171518659521043,"score_gpt":0.330605077151685,"score_spread":0.21345321119958072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992901332","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008849716,0.2967347,0.0008588403,0.29277167,0.08022295,0.00003709526,0.00041385178,0.00021944569,0.31989163],"genre_scores_gemma":[0.09931106,0.2682516,0.00087348506,0.13138162,0.053876236,0.00007202044,0.00046473555,0.00024595592,0.44552332],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993339,0.00026774383,0.00002809802,0.00006434001,0.00020339488,0.00010252747],"domain_scores_gemma":[0.99925417,0.00034777483,0.000058654103,0.000034954093,0.0001186097,0.00018587211],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010842801,0.0008708241,0.0004976848,0.0005947803,0.003317215,0.005197673,0.00060074247,0.0029915513,0.008740702],"category_scores_gemma":[0.0025722256,0.00025991222,0.00042755643,0.00066671846,0.004963309,0.004768519,0.002942162,0.0066414652,0.004789861],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004068421,0.000021524109,0.00034156462,0.0002915103,0.00000927476,0.00083682867,0.020119416,0.0000794737,0.00018063764,0.041750077,0.90811443,0.028214607],"study_design_scores_gemma":[0.0000014681857,0.000010724306,0.00012911289,0.00015287245,0.0000016351872,0.00029557224,0.0020044635,0.0000076604865,0.000021869093,0.0012621152,0.99610823,0.0000043837613],"about_ca_topic_score_codex":0.0049738614,"about_ca_topic_score_gemma":0.005833807,"teacher_disagreement_score":0.008740702,"about_ca_system_score_codex":0.0024668975,"about_ca_system_score_gemma":0.0018528432,"threshold_uncertainty_score":0.029240549},"labels":[],"label_agreement":null},{"id":"W1992971293","doi":"10.1172/jci58705","title":"Signaling at neuro/immune synapses","year":2012,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Eye Institute; School of Medicine, New York University; York University","keywords":"Neuroscience; Synapse; Immunological synapse; Biology; Immune system; Immunology; T cell; T-cell receptor","score_opus":0.36968888827985036,"score_gpt":0.43603656691616566,"score_spread":0.0663476786363153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992971293","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024914308,0.99661475,0.00033047702,0.0002156711,0.00018705227,0.0000067968354,0.000023475095,0.000016430604,0.002356137],"genre_scores_gemma":[0.0013025611,0.9968035,0.00030939057,0.00011363481,0.00014419605,0.000009143705,0.000031344938,0.000002196889,0.0012839437],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99985063,0.000022107666,0.000020369294,0.000030394478,0.000057199606,0.00001922173],"domain_scores_gemma":[0.99988437,0.0000361969,0.000019318863,0.0000059601443,0.00003722963,0.000017019725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042370116,0.0011075231,0.0014032519,0.0022312223,0.0003652758,0.0012568904,0.00095021114,0.0012759726,0.0034959603],"category_scores_gemma":[0.00034091846,0.0002680631,0.00037308043,0.0015459763,0.0007085165,0.0015123334,0.0007637532,0.0014359867,0.004548147],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075200274,0.00006180121,0.00019214897,0.010192413,0.00005464361,0.00050041295,0.00008777377,0.0003615958,0.008562887,0.007824145,0.019058954,0.953028],"study_design_scores_gemma":[0.000011005308,0.000056357894,0.00088328787,0.0021040207,0.00005064726,0.0023818724,0.00009484504,0.00009510781,0.0024794647,0.004408337,0.9874128,0.000022286758],"about_ca_topic_score_codex":0.00073740154,"about_ca_topic_score_gemma":0.0008941943,"teacher_disagreement_score":0.0034959603,"about_ca_system_score_codex":0.0006723845,"about_ca_system_score_gemma":0.00079275965,"threshold_uncertainty_score":0.011695147},"labels":[],"label_agreement":null},{"id":"W1993573575","doi":"10.1172/jci8592","title":"High-level expression of Egr-1 and Egr-1–inducible genes in mouse and human atherosclerosis","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":298,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health","keywords":"Biology; Gene expression; Lesion; Inflammation; Fibrous cap; Cell biology; Gene; Vascular smooth muscle; Molecular biology; Pathology; Endocrinology; Immunology; Medicine","score_opus":0.2051034322134506,"score_gpt":0.36824249383445734,"score_spread":0.16313906162100675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993573575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941855,0.002286851,0.0018962981,0.000055074142,0.000010005204,0.000016031587,0.00051104877,0.000035517427,0.0010038628],"genre_scores_gemma":[0.98897797,0.0025657648,0.003893084,0.00011355686,0.000017169998,0.00008299089,0.0019735633,0.000026062045,0.0023498728],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99982774,0.000031968324,0.000016647828,0.000051661984,0.00003815089,0.00003378999],"domain_scores_gemma":[0.9999318,0.000019220577,0.000014749582,0.0000135502305,0.000008280523,0.000012391821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028996976,0.00024518592,0.0002363,0.00068014814,0.00013043603,0.0002595091,0.000088252236,0.0002590004,0.0011279323],"category_scores_gemma":[0.00015929998,0.00017950179,0.00016938054,0.00021161178,0.00018128529,0.00010465589,0.000117661984,0.0003015142,0.0003857768],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050552795,0.000043723,0.0013650752,0.00004088258,0.00001421769,0.00015142528,0.00006079937,0.000042038413,0.9949114,0.000110301735,0.000044597906,0.0027101252],"study_design_scores_gemma":[0.00013347137,0.0018453781,0.11661461,0.00006280353,0.00020879677,0.008337343,0.00023903286,0.0009949335,0.8608952,0.00056942104,0.0100683775,0.000030449495],"about_ca_topic_score_codex":0.0002369163,"about_ca_topic_score_gemma":0.00031407631,"teacher_disagreement_score":0.0011279323,"about_ca_system_score_codex":0.00015353267,"about_ca_system_score_gemma":0.00010073993,"threshold_uncertainty_score":0.003773272},"labels":[],"label_agreement":null},{"id":"W1993971647","doi":"10.1172/jci32108","title":"Geranylgeranyltransferase I as a target for anti-cancer drugs","year":2007,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Farnesyltransferase; Prenylation; Gene; Druggability; Enzyme; Amino acid; GTPase; Cancer research; Biology; Cysteine; Biochemistry; Chemistry","score_opus":0.13099600877447048,"score_gpt":0.45102854811761106,"score_spread":0.3200325393431406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993971647","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00020636756,0.9967159,0.00017895411,0.00068807264,0.00049446215,0.0000053062768,0.000013700326,0.000017585226,0.0016796408],"genre_scores_gemma":[0.0012737161,0.99528307,0.0003550727,0.0005881751,0.00036679328,0.000010440541,0.000034158667,0.0000034217042,0.002085202],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99986136,0.000022647206,0.0000137420675,0.000024489334,0.00006155444,0.000016302372],"domain_scores_gemma":[0.9998254,0.0000577239,0.00002279399,0.000007976378,0.00005412935,0.000032055592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004748846,0.0008700324,0.0013140204,0.0016105926,0.0002932034,0.0007143629,0.00090542366,0.0012312152,0.0031893812],"category_scores_gemma":[0.0003770334,0.0002858865,0.00036241557,0.0015525047,0.0005704266,0.0013760548,0.00049289153,0.0022634433,0.0035879777],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023829206,0.00016362758,0.00018397617,0.00511169,0.00007842735,0.00048584974,0.000053295236,0.00052861456,0.0076830857,0.0051553426,0.07676293,0.9035548],"study_design_scores_gemma":[0.00004309625,0.00009928404,0.00049001974,0.0005655354,0.00004190829,0.0010947158,0.00002280995,0.00008397777,0.00088650134,0.0013626518,0.99529797,0.000011530289],"about_ca_topic_score_codex":0.0005321981,"about_ca_topic_score_gemma":0.0013922633,"teacher_disagreement_score":0.0031893812,"about_ca_system_score_codex":0.00071771163,"about_ca_system_score_gemma":0.00055470114,"threshold_uncertainty_score":0.010669529},"labels":[],"label_agreement":null},{"id":"W1994259848","doi":"10.1172/jci33375","title":"β Cell transplantation and immunosuppression: can’t live with it, can’t live without it","year":2007,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Immunosuppression; Islet cell transplantation; Transplantation; Medicine; Insulin; Diabetes mellitus; Regeneration (biology); Bioinformatics; Islet; Cell; Immunology; Cancer research; Intensive care medicine; Biology; Internal medicine; Endocrinology; Cell biology; Genetics","score_opus":0.06100502845586089,"score_gpt":0.34267460224108387,"score_spread":0.281669573785223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994259848","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014646468,0.008492363,0.00031929807,0.9615601,0.02408622,0.0000174564,0.000014960683,0.00004070907,0.0040043467],"genre_scores_gemma":[0.010498923,0.009329035,0.00062493066,0.892192,0.07837118,0.000036462883,0.0000228318,0.000021948148,0.008902647],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998495,0.00061004615,0.0001442714,0.00014809071,0.0004723337,0.00013032345],"domain_scores_gemma":[0.9979583,0.0012478088,0.00012778182,0.00008070358,0.00031053898,0.00027487215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017733477,0.00086783257,0.0009962707,0.00048051542,0.0015938872,0.0016843291,0.0007908055,0.01664422,0.0035072379],"category_scores_gemma":[0.00840912,0.00036841363,0.0009116782,0.0004031113,0.0027674749,0.003286666,0.0006211856,0.020614536,0.004112936],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020373196,0.00020370612,0.0016159518,0.00020534826,0.000043402488,0.011268646,0.00022904258,0.00011618809,0.0011453658,0.005614951,0.93032515,0.04902846],"study_design_scores_gemma":[0.00037148382,0.00036017434,0.0020966672,0.0004731478,0.00005943599,0.042373993,0.00057977554,0.0008486491,0.00093211816,0.016199617,0.93563586,0.0000690109],"about_ca_topic_score_codex":0.00071226264,"about_ca_topic_score_gemma":0.0010905135,"teacher_disagreement_score":0.01664422,"about_ca_system_score_codex":0.0017054481,"about_ca_system_score_gemma":0.00072231406,"threshold_uncertainty_score":0.012373984},"labels":[],"label_agreement":null},{"id":"W1994485752","doi":"10.1172/jci35243","title":"Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Kinase; Phosphorylation; Biology; GSK-3; Molecular biology; Internal medicine; Endocrinology; Cell biology; Medicine","score_opus":0.04803445705178283,"score_gpt":0.30602018719148194,"score_spread":0.2579857301396991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994485752","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944405,0.0018046589,0.0010917776,0.00008146924,0.000036540005,0.00003409624,0.00045493184,0.000136889,0.0019191843],"genre_scores_gemma":[0.9944883,0.0010903764,0.0014424105,0.00006627272,0.00001782672,0.000048344406,0.00053240557,0.000025724148,0.002288419],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987125,0.000014650811,0.0000159804,0.000028184293,0.00003091937,0.00003902913],"domain_scores_gemma":[0.9998846,0.0000069115426,0.00003677934,0.0000116751435,0.0000061723495,0.000053740187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015215194,0.00044421878,0.00022206016,0.00028408022,0.00011241533,0.00023729318,0.00015304565,0.00016199591,0.0008599808],"category_scores_gemma":[0.000083355386,0.00023544316,0.00029926063,0.00014392022,0.00025396867,0.0001221711,0.00020524453,0.0005133675,0.0004572475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014781955,0.00002267215,0.00017398986,0.000026651032,0.0000028165548,0.000027188005,0.0000104604305,0.00003729154,0.99894565,0.000027884265,0.000031646923,0.000545861],"study_design_scores_gemma":[0.000119034565,0.0010501693,0.019414302,0.000025938158,0.000022998503,0.00026437754,0.000043750046,0.0011093607,0.97584254,0.00007814455,0.0020206303,0.00000864914],"about_ca_topic_score_codex":0.0009019356,"about_ca_topic_score_gemma":0.0019017879,"teacher_disagreement_score":0.0009019356,"about_ca_system_score_codex":0.000280505,"about_ca_system_score_gemma":0.0002978122,"threshold_uncertainty_score":0.0028768778},"labels":[],"label_agreement":null},{"id":"W1994578552","doi":"10.1172/jci35339","title":"Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; School of Medicine, Emory University; National Institute on Aging; National Institutes of Health; Emory University","keywords":"Joubert syndrome; Biology; Tropomyosin receptor kinase B; Brainstem; Cerebellum; Neurite; Neurotrophic factors; Decussation; Knockout mouse; Cell biology; Neurotrophin; Neuroscience; Receptor; Genetics; Cilium","score_opus":0.03352319219008865,"score_gpt":0.29829555512642186,"score_spread":0.2647723629363332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994578552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931084,0.0020428302,0.002787735,0.00019586191,0.00003609899,0.000026343623,0.0003330186,0.00014452754,0.0013252719],"genre_scores_gemma":[0.99057204,0.00117225,0.0025383001,0.000100931364,0.000013691894,0.00006958054,0.0005323152,0.0000689826,0.004931972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975544,0.00004129599,0.00002358301,0.000059903134,0.000065964305,0.0000538688],"domain_scores_gemma":[0.99973816,0.000028745646,0.00010547008,0.000019148234,0.00001542222,0.00009312879],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021291315,0.00046861116,0.00025561618,0.000705947,0.0002810956,0.0004598794,0.00042046158,0.0005682075,0.0009905664],"category_scores_gemma":[0.00014499795,0.00043481807,0.00027365747,0.00016625773,0.00046226414,0.00025121603,0.000349945,0.0009004647,0.0005731297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095312644,0.000028135619,0.00022897396,0.000022549144,0.0000060639513,0.00010501493,0.0000249258,0.00006602195,0.9985415,0.0001345754,0.000046250854,0.00070065993],"study_design_scores_gemma":[0.00006809884,0.00026747832,0.0098831635,0.0000191527,0.000034882865,0.0006691331,0.00006414895,0.002593882,0.9820816,0.0001684892,0.0041386248,0.00001135978],"about_ca_topic_score_codex":0.0008104568,"about_ca_topic_score_gemma":0.0014487492,"teacher_disagreement_score":0.0009905664,"about_ca_system_score_codex":0.00073273754,"about_ca_system_score_gemma":0.00024898836,"threshold_uncertainty_score":0.0053163767},"labels":[],"label_agreement":null},{"id":"W1994727775","doi":"10.1172/jci44474","title":"Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":163,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Health and Medical Research Council; Université de Sherbrooke","keywords":"Biology; Glutamate receptor; Synaptic cleft; Transporter; Biochemistry; Gene; Receptor","score_opus":0.044437873774249424,"score_gpt":0.35241810130637047,"score_spread":0.30798022753212106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994727775","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925748,0.0016761139,0.0025334693,0.00039938456,0.000088514425,0.000079328616,0.000663006,0.00014544738,0.001839955],"genre_scores_gemma":[0.9972371,0.00045278357,0.000987694,0.000136849,0.000031072308,0.000010980067,0.00026938983,0.000018142007,0.0008561028],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985933,0.000026336034,0.000017021666,0.000039734263,0.000035688325,0.000021902368],"domain_scores_gemma":[0.99981934,0.000049892104,0.00005252392,0.000011025236,0.000018502345,0.000048742815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013058774,0.0007995504,0.0003124549,0.00033422536,0.0003397854,0.00014058048,0.00018243687,0.00057350047,0.0014754379],"category_scores_gemma":[0.00041707754,0.00013248668,0.0001906962,0.00023590785,0.00053053786,0.000105036415,0.00028240593,0.00029672388,0.00034811007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016005347,0.00041246496,0.06391428,0.00065651454,0.00035695746,0.12502703,0.00070165994,0.0012256976,0.75204057,0.0017458603,0.0064645186,0.04585397],"study_design_scores_gemma":[0.00039818912,0.0024658067,0.36880025,0.0001433664,0.00059957855,0.4121734,0.00048060605,0.0047933105,0.1747653,0.0013483752,0.033910487,0.000121308636],"about_ca_topic_score_codex":0.0013012785,"about_ca_topic_score_gemma":0.0014702723,"teacher_disagreement_score":0.0014754379,"about_ca_system_score_codex":0.00022548858,"about_ca_system_score_gemma":0.00018797873,"threshold_uncertainty_score":0.004935801},"labels":[],"label_agreement":null},{"id":"W1994946944","doi":"10.1172/jci38201","title":"Foxa1 and Foxa2 regulate bile duct development in mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; U.S. Public Health Service; National Institute of Diabetes and Digestive and Kidney Diseases; University of Pennsylvania","keywords":"FOXA2; FOXA1; Biology; Transcription factor; Endocrinology; Internal medicine; Bile duct; Cancer research; Cell biology; Medicine; Genetics; Gene","score_opus":0.08314764188118096,"score_gpt":0.3706393687716617,"score_spread":0.28749172689048075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994946944","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778066,0.0027289228,0.010383686,0.0006741889,0.000108155094,0.00021185535,0.0020633554,0.000806992,0.0052162334],"genre_scores_gemma":[0.95384544,0.0026025004,0.014432429,0.00051450374,0.00009050078,0.0007458714,0.0019416948,0.00056605483,0.025261115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940324,0.000103511185,0.00005622956,0.00015029969,0.00013233615,0.00015436453],"domain_scores_gemma":[0.9994917,0.00007348873,0.00017518818,0.00006280611,0.000027221136,0.00016963862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006027116,0.0008612925,0.0005138869,0.001949005,0.0006822613,0.0007514492,0.00060032035,0.0012174862,0.004659894],"category_scores_gemma":[0.00034737645,0.001005926,0.0007298681,0.00042039843,0.0010069262,0.0006439455,0.00084001524,0.0013931951,0.0012305997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011351384,0.00028174362,0.00091829523,0.000057173784,0.000023461032,0.00034224655,0.000093152106,0.00024052477,0.9899155,0.0014047225,0.00033883183,0.0052493373],"study_design_scores_gemma":[0.0008840386,0.001334235,0.012382724,0.000079449586,0.00011645002,0.0029201363,0.00014827235,0.0037746977,0.9554232,0.0013913279,0.02149566,0.000049772363],"about_ca_topic_score_codex":0.000954951,"about_ca_topic_score_gemma":0.0016320219,"teacher_disagreement_score":0.004659894,"about_ca_system_score_codex":0.00091754383,"about_ca_system_score_gemma":0.00050241215,"threshold_uncertainty_score":0.01558888},"labels":[],"label_agreement":null},{"id":"W1995040137","doi":"10.1172/jci13712","title":"Glypicans: proteoglycans with a surprise","year":2001,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":361,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institutes of Health; March of Dimes Foundation","keywords":"Morphogenesis; Biology; Glypican 3; Heparan sulfate; Function (biology); Cell biology; Heparin; Genetics; Biochemistry; Gene","score_opus":0.14312054017075077,"score_gpt":0.44548030467022703,"score_spread":0.30235976449947627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995040137","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00080433825,0.98735064,0.00047619524,0.0048038047,0.0029371793,0.0000069113294,0.000015622152,0.000038269514,0.0035669478],"genre_scores_gemma":[0.0042598853,0.9846089,0.00044206897,0.0031497427,0.0019773112,0.000009988229,0.00003421603,0.000007343075,0.0055105328],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99989057,0.000019982841,0.000014559192,0.000017655746,0.00004626677,0.000010964354],"domain_scores_gemma":[0.9998591,0.00004877275,0.000018120418,0.0000096928825,0.000033687378,0.000030574578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000438084,0.0011132174,0.00080552883,0.0009778142,0.00040532448,0.0011091353,0.0005207036,0.0013604752,0.0017749488],"category_scores_gemma":[0.00054160465,0.00019487945,0.0002701526,0.00088793016,0.001105615,0.0017192471,0.0006886031,0.0027465797,0.002063034],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002666456,0.000083775674,0.0003130861,0.0036352824,0.000075770666,0.0014673496,0.00014746888,0.00027513216,0.0085,0.022227144,0.14163215,0.82137614],"study_design_scores_gemma":[0.000031424297,0.00008395859,0.0006973976,0.0007409185,0.00003676831,0.005875212,0.00010230577,0.000096792544,0.0025291054,0.0094776135,0.98031265,0.000015872778],"about_ca_topic_score_codex":0.00043004393,"about_ca_topic_score_gemma":0.0006517926,"teacher_disagreement_score":0.0017749488,"about_ca_system_score_codex":0.00058604043,"about_ca_system_score_gemma":0.000501961,"threshold_uncertainty_score":0.005937755},"labels":[],"label_agreement":null},{"id":"W1995051972","doi":"10.1172/jci9258","title":"Enhanced intestinal transepithelial antigen transport in allergic rats is mediated by IgE and CD23 (FcεRII)","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Medical Research Council; Medical Research Council Canada","keywords":"CD23; Antigen; Immunoglobulin E; Sensitization; Chemistry; Antibody; Horseradish peroxidase; Transcytosis; Receptor; Immunology; Molecular biology; Biology; Cell biology; Biochemistry; Endocytosis","score_opus":0.02836230127404874,"score_gpt":0.29517622438813257,"score_spread":0.2668139231140838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995051972","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969482,0.0010935015,0.0013092854,0.00006728302,0.000020106363,0.000026672447,0.000051487117,0.00007037971,0.00041314503],"genre_scores_gemma":[0.99675864,0.0007014747,0.0014307436,0.00004068349,0.000022156219,0.000032957807,0.00007580784,0.000011985211,0.00092567335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997923,0.000046345016,0.000013888861,0.000050853952,0.00003667305,0.00005989135],"domain_scores_gemma":[0.9998294,0.000021925662,0.00005339073,0.000019512101,0.000013242092,0.000062524945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024234902,0.00077593944,0.00043137095,0.0004555041,0.00023317008,0.00027704344,0.00021509867,0.00041715807,0.001445309],"category_scores_gemma":[0.00020123064,0.0002805708,0.00030392173,0.00016073805,0.0004461378,0.0005249235,0.00021528374,0.0010058226,0.00026250648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031313076,0.00007413041,0.00018308545,0.000031765547,0.0000034951418,0.00011540592,0.000011682839,0.0000140477,0.99839145,0.000039419694,0.0000138859305,0.00080849486],"study_design_scores_gemma":[0.000072527655,0.0037662878,0.014261406,0.0000065041486,0.000045197627,0.0009825384,0.00005368631,0.0004260959,0.9795303,0.00009598809,0.00074993854,0.0000095880905],"about_ca_topic_score_codex":0.00034626893,"about_ca_topic_score_gemma":0.000598314,"teacher_disagreement_score":0.001445309,"about_ca_system_score_codex":0.00034390928,"about_ca_system_score_gemma":0.00016540986,"threshold_uncertainty_score":0.004835069},"labels":[],"label_agreement":null},{"id":"W1995341351","doi":"10.1172/jci13073","title":"Osteolysis and cancer","year":2001,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cancer; Osteolysis; Medicine; Oncology; Cancer research; Internal medicine; Surgery","score_opus":0.1493886018511252,"score_gpt":0.4461052461273792,"score_spread":0.296716644276254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995341351","genre_codex":"review","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0104793515,0.84009784,0.0012391182,0.019728178,0.004283354,0.00010033828,0.001045345,0.00018562407,0.12284084],"genre_scores_gemma":[0.15715612,0.6879303,0.002264472,0.020291967,0.0067377025,0.00023042498,0.002324446,0.0001004897,0.12296413],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99945194,0.00009376149,0.000030809406,0.00008729794,0.0002307013,0.00010549098],"domain_scores_gemma":[0.99961805,0.000058628473,0.00007759534,0.000029920004,0.000119651144,0.00009615267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049259304,0.00044308178,0.00059656816,0.0008290396,0.0006234694,0.0017902112,0.000529589,0.0015598795,0.027256085],"category_scores_gemma":[0.0010035603,0.00010603644,0.00031719534,0.0012433887,0.0008716505,0.0005061832,0.0013205531,0.0015909667,0.0070981993],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041645067,0.00026117807,0.006215011,0.0036573706,0.00010889016,0.0024118824,0.0005015092,0.00035592876,0.008603331,0.072996445,0.2883728,0.6160991],"study_design_scores_gemma":[0.00003955893,0.00012215132,0.0046485565,0.00067628967,0.000024923891,0.0055452655,0.00016365366,0.00004732151,0.00076065905,0.0094965305,0.97846496,0.000010134384],"about_ca_topic_score_codex":0.0023596562,"about_ca_topic_score_gemma":0.002745509,"teacher_disagreement_score":0.027256085,"about_ca_system_score_codex":0.001327581,"about_ca_system_score_gemma":0.0013524559,"threshold_uncertainty_score":0.09118062},"labels":[],"label_agreement":null},{"id":"W1997664301","doi":"10.1172/jci19930","title":"Pre–B cell colony–enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":594,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Hospital for Sick Children; Toronto General Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; Amgen","keywords":"Apoptosis; Inflammation; Sepsis; Tumor necrosis factor alpha; Immunology; Biology; Cytokine; Downregulation and upregulation; Molecular biology; Biochemistry; Gene","score_opus":0.041278757108848874,"score_gpt":0.3440752805889518,"score_spread":0.30279652348010294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997664301","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939129,0.0037575036,0.00097221974,0.00017891452,0.000042629385,0.00005058306,0.000057118566,0.00006486773,0.0009632124],"genre_scores_gemma":[0.99692106,0.0011147413,0.0010246957,0.00006858254,0.00003040402,0.000046912446,0.00024546398,0.000009345108,0.00053882983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981195,0.000087419954,0.000015855221,0.000010496414,0.00003249841,0.000041742715],"domain_scores_gemma":[0.99972314,0.00007952521,0.0000563226,0.000031672913,0.000027063648,0.0000821985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031610945,0.00045868658,0.00041019285,0.00022460152,0.00012408613,0.0002293114,0.00015896207,0.00022740582,0.00079105457],"category_scores_gemma":[0.0006257703,0.000093751616,0.00012262558,0.000116037896,0.00041230198,0.0001430022,0.00015742831,0.0008022246,0.00020053229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010020835,0.0019824193,0.0010261482,0.0002441927,0.000029358716,0.00031116742,0.000053764266,0.000405474,0.953085,0.0002790098,0.00047350422,0.03208918],"study_design_scores_gemma":[0.002033158,0.03773598,0.020350778,0.00006612372,0.00007498353,0.0022148187,0.00007574358,0.0024101855,0.9288055,0.00030711803,0.005910076,0.00001548106],"about_ca_topic_score_codex":0.00026009243,"about_ca_topic_score_gemma":0.00035485678,"teacher_disagreement_score":0.00079105457,"about_ca_system_score_codex":0.00017934457,"about_ca_system_score_gemma":0.00030656002,"threshold_uncertainty_score":0.002646327},"labels":[],"label_agreement":null},{"id":"W1997694334","doi":"10.1172/jci41158","title":"Enabling stem cell therapies through synthetic stem cell–niche engineering","year":2010,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":171,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; University Health Network; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Stem Cell Network","keywords":"Stem cell; Niche; Stem cell niche; Biology; Cell biology; Progenitor cell; Ecology","score_opus":0.1560639909129672,"score_gpt":0.3954423933539506,"score_spread":0.2393784024409834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997694334","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013558881,0.99095553,0.0031304343,0.00020016091,0.00023481168,0.000019771607,0.000017820541,0.000027314838,0.0040583047],"genre_scores_gemma":[0.0057151755,0.9886643,0.0030878715,0.0001205818,0.00012448424,0.000025103845,0.000038555845,0.000004935609,0.0022190025],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99982965,0.000023396045,0.00001674162,0.000024747938,0.00008988246,0.000015663383],"domain_scores_gemma":[0.9998723,0.00006136919,0.000020611067,0.0000063138136,0.000029156048,0.000010192093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046776433,0.0006722016,0.00076405314,0.0016374649,0.0001637082,0.0005845666,0.0005354574,0.00075602136,0.0019583157],"category_scores_gemma":[0.00031441727,0.00022278077,0.00032125518,0.0010447844,0.00044204862,0.00076323084,0.00034681373,0.00070007634,0.0020074989],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040473788,0.00011317645,0.00016481719,0.007079478,0.000038885493,0.00032705526,0.00005836797,0.0013222668,0.031989537,0.008177661,0.0066996827,0.94398856],"study_design_scores_gemma":[0.000021330898,0.00016663923,0.0007113335,0.0010868647,0.000051830404,0.0023714195,0.00006696296,0.00051763025,0.020868829,0.003648469,0.9704607,0.000028003155],"about_ca_topic_score_codex":0.00052543834,"about_ca_topic_score_gemma":0.00097109395,"teacher_disagreement_score":0.0019583157,"about_ca_system_score_codex":0.00036541303,"about_ca_system_score_gemma":0.00039090315,"threshold_uncertainty_score":0.006551206},"labels":[],"label_agreement":null},{"id":"W1998183802","doi":"10.1172/jci44723","title":"Death effector domain–containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; University of Tokyo","keywords":"Decidualization; Decidua; Decidual cells; Biology; Stromal cell; Cell biology; Placenta; Uterus; Placentation; Endocrinology; Internal medicine; Embryo; Andrology; Cancer research; Pregnancy; Fetus; Medicine; Genetics","score_opus":0.05634501454228507,"score_gpt":0.35988889947389446,"score_spread":0.3035438849316094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998183802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884616,0.002289036,0.0061445916,0.00024446138,0.00004863269,0.000051248237,0.0014577567,0.00017879513,0.0011237836],"genre_scores_gemma":[0.99305665,0.0007284053,0.0029793242,0.00008802004,0.000009619541,0.00006793837,0.0010472654,0.000042200754,0.001980555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998098,0.000034133143,0.000034658995,0.000050184964,0.000033647702,0.00003762776],"domain_scores_gemma":[0.9996387,0.000056805682,0.00014182113,0.000033902696,0.000013286998,0.00011559848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002505847,0.00041722806,0.00027789344,0.00055271224,0.0002387326,0.00037308043,0.00028747748,0.00042825233,0.0015138779],"category_scores_gemma":[0.0002761305,0.00038414958,0.00025530736,0.00018610203,0.00042598022,0.00021750212,0.0003644462,0.0006226333,0.0004949742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042154314,0.00005426736,0.0010021918,0.000054921187,0.000008788831,0.00041309107,0.00002304151,0.00010299118,0.99552494,0.00033657666,0.00007928678,0.00197835],"study_design_scores_gemma":[0.00021238293,0.0005005455,0.021033505,0.00003264638,0.000057081903,0.0036553068,0.00007552992,0.0023386755,0.96348387,0.00030688994,0.008288835,0.000014726181],"about_ca_topic_score_codex":0.00019879609,"about_ca_topic_score_gemma":0.00022759149,"teacher_disagreement_score":0.0015138779,"about_ca_system_score_codex":0.00032574873,"about_ca_system_score_gemma":0.0002383555,"threshold_uncertainty_score":0.0050643682},"labels":[],"label_agreement":null},{"id":"W1998212202","doi":"10.1172/jci34694","title":"Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":366,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Elastase; Neutrophil elastase; Inflammation; Proteinase 3; Immunology; Pancreatic elastase; Medicine; Chemistry; Enzyme; Myeloperoxidase; Biochemistry","score_opus":0.03307670916146587,"score_gpt":0.3067229042233473,"score_spread":0.2736461950618814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998212202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915651,0.0024299992,0.0024535372,0.00046887124,0.000040813873,0.00011252781,0.0003627786,0.00036426514,0.0022021036],"genre_scores_gemma":[0.988862,0.0017185496,0.00451801,0.00024712834,0.000050434926,0.00017241023,0.00042510568,0.00006530313,0.0039410205],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994785,0.00014435624,0.000056519715,0.00008811722,0.00009444487,0.00013802366],"domain_scores_gemma":[0.99945825,0.000093851,0.00019931303,0.00005593314,0.000027640393,0.00016496485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000497277,0.0012342252,0.000544773,0.0009264982,0.00023555587,0.00053326524,0.00036610637,0.00077776465,0.001344957],"category_scores_gemma":[0.00039019447,0.00047479835,0.00042992813,0.00019101506,0.0006888709,0.00052593567,0.00033233644,0.0013769679,0.000450663],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017683981,0.00048946147,0.0005079073,0.00009145222,0.00001821745,0.00031528802,0.00004305009,0.000116481926,0.9923724,0.0004549288,0.00014668563,0.0036758503],"study_design_scores_gemma":[0.00086407195,0.008838335,0.0125964945,0.00006986335,0.000132745,0.002820519,0.00008670978,0.0024934341,0.96512,0.00055490626,0.0063991267,0.000023843984],"about_ca_topic_score_codex":0.00044634644,"about_ca_topic_score_gemma":0.0007137049,"teacher_disagreement_score":0.001344957,"about_ca_system_score_codex":0.00043007673,"about_ca_system_score_gemma":0.00030896132,"threshold_uncertainty_score":0.004499316},"labels":[],"label_agreement":null},{"id":"W1998595688","doi":"10.1172/jci13297","title":"Transplantable hematopoietic stem cells in human fetal liver have a CD34+ side population (SP)phenotype","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; U.S. Public Health Service; Genentech; National Cancer Institute; National Institutes of Health","keywords":"Stem cell; Biology; Haematopoiesis; Side population; CD34; Progenitor cell; CD38; Population; Cell biology; Adult stem cell; Immunology; Molecular biology; Endothelial stem cell; Cancer stem cell; In vitro; Medicine; Biochemistry","score_opus":0.0849607709331118,"score_gpt":0.3567320339922706,"score_spread":0.2717712630591588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998595688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98115426,0.0025547906,0.009421473,0.00010715294,0.000026320511,0.000120159406,0.00071332604,0.0002597637,0.0056427848],"genre_scores_gemma":[0.9842986,0.0012009979,0.0064540757,0.0000677766,0.000024490191,0.00007796301,0.0019700318,0.00004077094,0.0058652433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999094,0.000015030161,0.000009579224,0.000018376864,0.000033231387,0.000014387677],"domain_scores_gemma":[0.99987996,0.000030676918,0.000018566254,0.000025620426,0.000012938103,0.00003209956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014787316,0.000212836,0.00021840858,0.00023676817,0.00010423668,0.00020731441,0.00009615695,0.00020368879,0.004025553],"category_scores_gemma":[0.00015327685,0.00012178308,0.00017655178,0.00017989946,0.00017177092,0.00017093618,0.00021998421,0.00035074208,0.001395594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017008062,0.000020420819,0.0014031966,0.000042978845,0.000005777077,0.00033751054,0.00004426033,0.00004644901,0.99111944,0.00018666293,0.00009555893,0.0065275873],"study_design_scores_gemma":[0.000038967915,0.001172842,0.025740186,0.000019416151,0.000034669887,0.00548594,0.00007339524,0.00063610583,0.9578957,0.00021804126,0.008677384,0.000007256711],"about_ca_topic_score_codex":0.00019866702,"about_ca_topic_score_gemma":0.00033791852,"teacher_disagreement_score":0.004025553,"about_ca_system_score_codex":0.000077040684,"about_ca_system_score_gemma":0.00011079444,"threshold_uncertainty_score":0.013466775},"labels":[],"label_agreement":null},{"id":"W1999182967","doi":"10.1172/jci63606","title":"Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; School of Medicine, New York University; York University; National Pancreas Foundation","keywords":"Pancreatic cancer; Cancer research; Stromal cell; Carcinogenesis; Biology; TLR7; Tumor microenvironment; Downregulation and upregulation; Pancreatic Intraepithelial Neoplasia; Pancreatic tumor; Cancer; Toll-like receptor; Immunology; Innate immune system; Immune system","score_opus":0.128326457070998,"score_gpt":0.42479803278184913,"score_spread":0.29647157571085114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999182967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95787656,0.013190731,0.006571363,0.0015942288,0.00021110362,0.0001063786,0.0023389538,0.000775645,0.017334929],"genre_scores_gemma":[0.9818419,0.0057515944,0.0033078592,0.0005952778,0.000056096982,0.00017554108,0.0016748401,0.0001084374,0.006488439],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999652,0.00010926248,0.000021013335,0.00009029603,0.0000618665,0.00006554401],"domain_scores_gemma":[0.9997576,0.000032904547,0.00008517593,0.000040321607,0.000024079704,0.00005984508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004195393,0.00045066728,0.00031190133,0.0010864073,0.00024999244,0.00064204755,0.00018430331,0.00044914975,0.004858628],"category_scores_gemma":[0.0003153966,0.00022003602,0.0003177974,0.00032457788,0.00039275235,0.00033375857,0.00047631015,0.0006932856,0.00091621897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005787324,0.001015877,0.051797006,0.00031628422,0.00026891197,0.0022530244,0.00026061706,0.00028216583,0.8553569,0.006589865,0.0057009887,0.070371136],"study_design_scores_gemma":[0.0007485619,0.0052309404,0.4530667,0.00041548125,0.0008110931,0.030252635,0.0011954298,0.003006678,0.3253468,0.006677522,0.17308132,0.00016680516],"about_ca_topic_score_codex":0.0002745633,"about_ca_topic_score_gemma":0.00019362572,"teacher_disagreement_score":0.004858628,"about_ca_system_score_codex":0.00029668174,"about_ca_system_score_gemma":0.00019857139,"threshold_uncertainty_score":0.01625377},"labels":[],"label_agreement":null},{"id":"W1999223726","doi":"10.1172/jci63375","title":"Tranexamic acid concentrations associated with human seizures inhibit glycine receptors","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":197,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; St. Michael's Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Savoy Foundation","keywords":"Tranexamic acid; Antifibrinolytic; Receptor; Pharmacology; Glycine receptor; Glycine; Medicine; Isoflurane; GABAA receptor; Propofol; Anesthesia; Chemistry; Internal medicine; Amino acid; Biochemistry; Surgery; Blood loss","score_opus":0.12971875959745763,"score_gpt":0.42007499725322783,"score_spread":0.29035623765577023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999223726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913557,0.0052463366,0.001112842,0.00015845138,0.000027893217,0.000026228354,0.00020984275,0.000034646728,0.0018281414],"genre_scores_gemma":[0.99819595,0.00092545175,0.0003446543,0.000058018046,0.00001140451,0.00001366405,0.0001390536,0.0000030529934,0.0003087818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998281,0.000054781238,0.00002038829,0.000016643517,0.000047871632,0.000032147465],"domain_scores_gemma":[0.99983203,0.0000327617,0.00008949059,0.000009379191,0.00001548631,0.000020814798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016250878,0.000337583,0.0002626106,0.00018419386,0.00010524586,0.00020265859,0.00011546934,0.0002272112,0.0018766347],"category_scores_gemma":[0.00045889322,0.000080724094,0.0001428565,0.00012587337,0.00014456156,0.00012589667,0.000109529996,0.0002502235,0.00023738573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018112147,0.000073041985,0.007973678,0.00015662878,0.00007578819,0.0010635445,0.000084800435,0.0001513025,0.9754833,0.0003232407,0.00036624022,0.012437209],"study_design_scores_gemma":[0.00016764914,0.0032441898,0.09373801,0.000040876308,0.000117443036,0.008110737,0.00014110513,0.0010389137,0.8863411,0.00028669392,0.0067585963,0.000014588638],"about_ca_topic_score_codex":0.0007041832,"about_ca_topic_score_gemma":0.0010082662,"teacher_disagreement_score":0.0018766347,"about_ca_system_score_codex":0.000261091,"about_ca_system_score_gemma":0.00016337808,"threshold_uncertainty_score":0.006277919},"labels":[],"label_agreement":null},{"id":"W1999644843","doi":"10.1172/jci12568","title":"Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":741,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Proinflammatory cytokine; Medicine; Fibrosis; Bronchoalveolar lavage; Pulmonary fibrosis; Lung; Pathology; Fibroblast; Inflammation; Cytokine; Immunology; Internal medicine; Biology; Cell culture","score_opus":0.038463102148587926,"score_gpt":0.36230013710150505,"score_spread":0.3238370349529171,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999644843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887916,0.005191763,0.0035744861,0.00019385165,0.00010592554,0.000087888744,0.0002921882,0.00015531133,0.0016069832],"genre_scores_gemma":[0.99136096,0.0023389433,0.0033169524,0.0001238524,0.000039938903,0.00011110912,0.00068138994,0.000026844646,0.001999911],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995704,0.00007248839,0.000039756138,0.0000572922,0.00009292633,0.00016703339],"domain_scores_gemma":[0.99973375,0.00007014537,0.00006588202,0.000043438515,0.000017831859,0.00006883424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035153696,0.0004159414,0.0003841976,0.00025083404,0.00017133108,0.00046560878,0.00016869987,0.00037004796,0.0012915406],"category_scores_gemma":[0.0002120254,0.00020214525,0.00039356694,0.00026665276,0.00049704785,0.00024143829,0.0002476018,0.0011268965,0.00045430512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019629864,0.00011109844,0.000119974815,0.000038461512,0.0000058636647,0.00009060234,0.00001881521,0.000033399152,0.99854016,0.0000749264,0.000030285964,0.0007401757],"study_design_scores_gemma":[0.00011308371,0.0025604141,0.004149894,0.000021173142,0.00003150276,0.00058886263,0.000065890854,0.00067580753,0.98959583,0.00011583014,0.0020765567,0.0000050883377],"about_ca_topic_score_codex":0.0002485434,"about_ca_topic_score_gemma":0.00045407022,"teacher_disagreement_score":0.0012915406,"about_ca_system_score_codex":0.00037301957,"about_ca_system_score_gemma":0.00025967616,"threshold_uncertainty_score":0.0043206215},"labels":[],"label_agreement":null},{"id":"W1999950133","doi":"10.1172/jci24343","title":"The great betrayal Fraud in science","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Betrayal; Political science; Law","score_opus":0.6000076959296559,"score_gpt":0.635762690875225,"score_spread":0.03575499494556911,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999950133","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":"methods","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":"methods","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009417489,0.09836864,0.0042809686,0.5653176,0.021380123,0.000036275913,0.000052645213,0.00009082433,0.30105555],"genre_scores_gemma":[0.4218452,0.07783137,0.004490383,0.3093083,0.029471204,0.00015039995,0.00009822084,0.00021717513,0.15658772],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.98831254,0.0059931776,0.00037160795,0.00064185687,0.0039650523,0.0007157652],"domain_scores_gemma":[0.97985965,0.014942869,0.0013225971,0.0010154014,0.0021591268,0.0007003899],"candidate_categories":["metaresearch","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0068805967,0.00039939294,0.0005003747,0.0017254313,0.009770337,0.014185144,0.0012868593,0.0071635926,0.002911269],"category_scores_gemma":[0.026592849,0.0005281697,0.0004639173,0.001887413,0.026660476,0.011908933,0.0042869155,0.009767065,0.0010884679],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016712838,0.000013627683,0.00031107882,0.000100662786,0.000012621866,0.00034668465,0.014840967,0.00009179762,0.000060111015,0.5587756,0.40656787,0.018862095],"study_design_scores_gemma":[0.0000072843977,0.000015210684,0.00037695974,0.00053933245,0.000009796378,0.0005007319,0.0044641695,0.0001761307,0.00015510296,0.11821147,0.875525,0.000018849045],"about_ca_topic_score_codex":0.004538841,"about_ca_topic_score_gemma":0.0053960998,"teacher_disagreement_score":0.9931194,"about_ca_system_score_codex":0.0053001046,"about_ca_system_score_gemma":0.0052218963,"threshold_uncertainty_score":0.03845513},"labels":[],"label_agreement":null},{"id":"W2000180809","doi":"10.1172/jci65634","title":"Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Children’s Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"ATRX; Telomere; Biology; DNA damage; Cell biology; Cancer research; Mutation; Genetics; DNA; Gene","score_opus":0.03927356218154909,"score_gpt":0.31483743901136907,"score_spread":0.27556387682982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000180809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99744165,0.0011686076,0.00042723923,0.00003653013,0.000008238393,0.00001020891,0.00032513402,0.000063977524,0.00051848165],"genre_scores_gemma":[0.9962591,0.00091974187,0.0004952925,0.000028869676,0.0000053784306,0.000016764478,0.0005041101,0.000015642703,0.0017551983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987996,0.000016508253,0.000017539041,0.00003504586,0.00002918448,0.000021779137],"domain_scores_gemma":[0.99988365,0.000015595006,0.00004513296,0.000013835372,0.0000063558246,0.000035471243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119366494,0.00047312788,0.0002541581,0.00039613445,0.00012360631,0.00017877243,0.00013635165,0.00023092004,0.0015271789],"category_scores_gemma":[0.00011642926,0.0001785062,0.0001765437,0.00019691804,0.00032298293,0.00011689883,0.00021566196,0.00038433677,0.00026544635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043638356,0.00004293025,0.0014315537,0.000041320003,0.000015986348,0.00062767835,0.000021356995,0.000052875406,0.9951255,0.00005311233,0.000057545007,0.0020936935],"study_design_scores_gemma":[0.00011490423,0.0022999023,0.05771272,0.00002211712,0.00008791405,0.010176142,0.00010407139,0.00053886615,0.92428243,0.00013984917,0.004508552,0.000012464858],"about_ca_topic_score_codex":0.00037548764,"about_ca_topic_score_gemma":0.00070575083,"teacher_disagreement_score":0.0015271789,"about_ca_system_score_codex":0.00018680053,"about_ca_system_score_gemma":0.00016204751,"threshold_uncertainty_score":0.0051089525},"labels":[],"label_agreement":null},{"id":"W2000268599","doi":"10.1172/jci22382","title":"Unbuckling lipodystrophy from insulin resistance and hypertension","year":2004,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Lipodystrophy; Insulin resistance; Medicine; Internal medicine; Endocrinology; Insulin; Immunology; Human immunodeficiency virus (HIV)","score_opus":0.03421267541240828,"score_gpt":0.2838585953112628,"score_spread":0.2496459198988545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000268599","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028079167,0.0058275657,0.0013357004,0.8876526,0.03822132,0.00019410903,0.00026689688,0.00030217058,0.03812042],"genre_scores_gemma":[0.18142861,0.010604513,0.0017271023,0.5896225,0.14499475,0.0002640718,0.00037093917,0.000114162045,0.07087338],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994597,0.00017052641,0.0000592063,0.00005654054,0.00015847919,0.000095538584],"domain_scores_gemma":[0.9991303,0.00049021246,0.00007608784,0.000052961983,0.00011414331,0.0001363343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000619288,0.0007953994,0.00079992047,0.00035271174,0.0007574152,0.0009954035,0.00054819515,0.010549777,0.0045755184],"category_scores_gemma":[0.004712631,0.00027351454,0.0005351647,0.00023717171,0.0010270444,0.0007047504,0.00034961756,0.006525241,0.00407164],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011758597,0.00034623957,0.0046150465,0.00038684986,0.000081807164,0.16731976,0.00017381535,0.00041801727,0.0059752734,0.009114069,0.7427228,0.06767041],"study_design_scores_gemma":[0.0016420343,0.00093994394,0.017254336,0.00048174447,0.00012626195,0.1736724,0.00028445225,0.002962402,0.0044119707,0.027296625,0.77083683,0.00009091272],"about_ca_topic_score_codex":0.0005575927,"about_ca_topic_score_gemma":0.00097547594,"teacher_disagreement_score":0.010549777,"about_ca_system_score_codex":0.0013518197,"about_ca_system_score_gemma":0.00053996703,"threshold_uncertainty_score":0.015306652},"labels":[],"label_agreement":null},{"id":"W2000433774","doi":"10.1172/jci22588","title":"Severe combined immunodeficiency caused by deficiency in either the δ or the ε subunit of CD3","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cytodiagnostics (Canada)","funders":"Institut National de la Santé et de la Recherche Médicale","keywords":"Thymocyte; Biology; Immunodeficiency; CD8; Mutation; Haplotype; Severe combined immunodeficiency; CD3; Gene; Genetics; Protein subunit; T-cell receptor; Fetus; Molecular biology; T cell; Genotype; Antigen; Immune system","score_opus":0.04156642247161749,"score_gpt":0.3162717148576206,"score_spread":0.27470529238600316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000433774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99806577,0.00079201895,0.00049737695,0.000024871955,0.000003908993,0.000010666856,0.00004137985,0.000011544195,0.0005523634],"genre_scores_gemma":[0.9991304,0.0003268872,0.00032304955,0.000016824295,0.000006990919,0.000005384208,0.00006563588,0.0000015688272,0.00012328813],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99987805,0.000030337624,0.00001615763,0.000024855623,0.000023463317,0.000027079046],"domain_scores_gemma":[0.9998185,0.00005292477,0.000055783017,0.00001225014,0.000008931676,0.000051675255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001653006,0.0007035979,0.00019560437,0.0004423043,0.00021587306,0.00013582947,0.00016440102,0.0003059994,0.00086548115],"category_scores_gemma":[0.0004170907,0.00016805927,0.00016251048,0.00023355722,0.00038992078,0.00014770405,0.00018353642,0.00034733405,0.00012383495],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027741056,0.0003203812,0.22472101,0.00035127075,0.00017786941,0.08319391,0.0005240362,0.00053545437,0.65635824,0.0011296179,0.0003912383,0.029522873],"study_design_scores_gemma":[0.00043273784,0.005196803,0.4088447,0.00007987767,0.0004178997,0.46772814,0.0003609109,0.0022180828,0.10722479,0.0007387537,0.006725153,0.00003212426],"about_ca_topic_score_codex":0.00040557998,"about_ca_topic_score_gemma":0.00037381132,"teacher_disagreement_score":0.00086548115,"about_ca_system_score_codex":0.00014396882,"about_ca_system_score_gemma":0.00015578377,"threshold_uncertainty_score":0.0028953552},"labels":[],"label_agreement":null},{"id":"W2000665430","doi":"10.1172/jci23606","title":"FGF-21 as a novel metabolic regulator","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2089,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Hospital for Sick Children; Eli Lilly and Company","keywords":"FGF21; Fibroblast growth factor; Diabetes mellitus; Regulator; Genetically modified mouse; Endocrinology; Transgene; Obesity; Internal medicine; Hypoglycemia; Population; Medicine; Negative regulator; Biology; Signal transduction; Receptor; Cell biology; Biochemistry; Gene","score_opus":0.07010678309674791,"score_gpt":0.40147129151505273,"score_spread":0.33136450841830484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000665430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7762041,0.16238686,0.026434688,0.0038036264,0.0012301469,0.00016633421,0.00086446846,0.00053556415,0.028374158],"genre_scores_gemma":[0.94092226,0.034702875,0.0133192325,0.0006187388,0.00044143366,0.00010006726,0.00059211015,0.000029180002,0.009274062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991894,0.000016389864,0.0000053368863,0.000014485676,0.000030038183,0.000014807783],"domain_scores_gemma":[0.9999577,0.000007501641,0.000008000075,0.0000035714115,0.000007723319,0.000015498008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014596498,0.00030874164,0.0002085752,0.000206795,0.0002418675,0.0004294829,0.00022016214,0.00039319176,0.0008112932],"category_scores_gemma":[0.00010324626,0.00007749095,0.00021934038,0.00011283246,0.0002480264,0.00019993681,0.0001981689,0.00043130925,0.00031500746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003073406,0.000050536604,0.00051620195,0.0001407728,0.000015366211,0.00067891617,0.000025155716,0.00025222558,0.9687011,0.0026733289,0.00063869084,0.026000338],"study_design_scores_gemma":[0.00009319757,0.0009550169,0.0036934882,0.0000318794,0.000078032135,0.0036027627,0.000041190735,0.0012841508,0.85637504,0.00090885244,0.13290885,0.000027634142],"about_ca_topic_score_codex":0.00037069517,"about_ca_topic_score_gemma":0.00062218483,"teacher_disagreement_score":0.0008112932,"about_ca_system_score_codex":0.0003574566,"about_ca_system_score_gemma":0.00020871806,"threshold_uncertainty_score":0.0027139783},"labels":[],"label_agreement":null},{"id":"W2001079898","doi":"10.1172/jci10714","title":"Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses","year":2001,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Toronto","funders":"Medical Research Council; Medical Research Council Canada; Elizabeth Glaser Pediatric AIDS Foundation; Rockefeller Foundation","keywords":"Seroconversion; Epitope; CTL*; Virology; Immunology; Cytotoxic T cell; Biology; HIV vaccine; HIV Antigens; Antigen; Antibody; CD8; Medicine; Virus; Viral disease; Vaccine trial; Genetics","score_opus":0.10567943926186349,"score_gpt":0.3657552754681462,"score_spread":0.2600758362062827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001079898","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99454075,0.00065962196,0.00012300815,0.0016690394,0.000057714213,0.00002124828,0.00003518232,0.000023246777,0.002870153],"genre_scores_gemma":[0.99608314,0.00030042976,0.00009333252,0.0014871806,0.00022702492,0.0000091361035,0.000060326704,0.000007178003,0.0017322438],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99963164,0.00008438228,0.0000314057,0.000060458184,0.00004895857,0.00014302967],"domain_scores_gemma":[0.9989587,0.00030220876,0.00029281108,0.000097153876,0.00010750652,0.00024159435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004489072,0.00046495502,0.00039036042,0.00059425394,0.0013031283,0.0007776083,0.000390748,0.0018124052,0.0016378491],"category_scores_gemma":[0.0028569403,0.00032796303,0.00015590385,0.0003996485,0.0006920478,0.0003583577,0.00021013159,0.0010089393,0.00057624007],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014030858,0.0003196309,0.8900294,0.0000782977,0.000026981963,0.07848964,0.0012892727,0.00006568155,0.0048984042,0.00015966273,0.0026085197,0.020631354],"study_design_scores_gemma":[0.0001557974,0.0018498278,0.8021142,0.00006895985,0.000036710815,0.18644524,0.00093077566,0.0005399932,0.001303364,0.00020977392,0.006321086,0.000024314888],"about_ca_topic_score_codex":0.0030976508,"about_ca_topic_score_gemma":0.0049865143,"teacher_disagreement_score":0.0030976508,"about_ca_system_score_codex":0.0006471903,"about_ca_system_score_gemma":0.00023856969,"threshold_uncertainty_score":0.006159246},"labels":[],"label_agreement":null},{"id":"W2001200618","doi":"10.1172/jci31992","title":"Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Public Health Service; Stanford Bio-X; Yonsei University College of Medicine; Yonsei University; Cystic Fibrosis Foundation","keywords":"Vasoactive intestinal peptide; Mucus; Submucosal glands; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; Secretion; Exocrine gland; Endocrinology; Internal medicine; Acetylcholine; Carbachol; Biology; Neuropeptide; Medicine; Receptor","score_opus":0.04808780989089693,"score_gpt":0.40000897946695113,"score_spread":0.3519211695760542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001200618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99459344,0.0037579916,0.0007336731,0.0001194531,0.00001814328,0.000017315511,0.0001191733,0.000048822225,0.00059205014],"genre_scores_gemma":[0.99803287,0.00060437527,0.0005948518,0.00006472089,0.0000111211075,0.000009989682,0.00017238046,0.000008358123,0.00050132285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996107,0.00007642616,0.00003131625,0.00006466687,0.00013655057,0.000080346705],"domain_scores_gemma":[0.99959487,0.000073078016,0.00007713131,0.00005151875,0.000029371862,0.00017410045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025319838,0.0003116546,0.0007581208,0.00030880878,0.00019905154,0.00035815348,0.00018557985,0.00046848078,0.0015165817],"category_scores_gemma":[0.00061732094,0.00023187207,0.00037621896,0.00019192092,0.0005422155,0.0002915935,0.0006285321,0.0008525151,0.00034287217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003321657,0.00001668872,0.0024263912,0.0000327903,0.000014147239,0.00046378828,0.000018297185,0.000017899996,0.9945056,0.00001967404,0.00004130222,0.0021112459],"study_design_scores_gemma":[0.00006815619,0.002904804,0.2992302,0.000027207785,0.00012112957,0.01807953,0.0002053067,0.0008916492,0.6745138,0.00019634252,0.0037415454,0.00002033054],"about_ca_topic_score_codex":0.00040220868,"about_ca_topic_score_gemma":0.00036229572,"teacher_disagreement_score":0.0015165817,"about_ca_system_score_codex":0.00024974492,"about_ca_system_score_gemma":0.0002043235,"threshold_uncertainty_score":0.0050734878},"labels":[],"label_agreement":null},{"id":"W2001225006","doi":"10.1172/jci24013","title":"SDF-1 tells stem cells to mind their P’s and Ζ’s","year":2005,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Stromal cell; CXCR4; Stem cell; Cell biology; Chemokine; Receptor; Stromal cell-derived factor 1; Biology; Cancer research; Biochemistry","score_opus":0.10906605759361203,"score_gpt":0.36312921643963136,"score_spread":0.2540631588460193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001225006","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0060244547,0.0076571717,0.0006993093,0.9413446,0.034930672,0.000016510896,0.00004328654,0.000067870555,0.009216013],"genre_scores_gemma":[0.0895949,0.013807393,0.0016047342,0.76240224,0.09776086,0.00004244572,0.000058754857,0.000027068774,0.0347016],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996112,0.00018729038,0.000026813565,0.000035767058,0.00010278347,0.000036140107],"domain_scores_gemma":[0.99915576,0.00048271773,0.0000620294,0.000056175548,0.00014698056,0.000096279284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006204489,0.0004395552,0.00037439138,0.00020370803,0.00072416227,0.000996182,0.00030320283,0.005171792,0.003917331],"category_scores_gemma":[0.0044169878,0.00015173078,0.00035904555,0.00014953823,0.0013055725,0.0013517226,0.00031806141,0.0064225043,0.0024213584],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045794965,0.00009207449,0.0022186951,0.00025729716,0.000043938202,0.015765654,0.00033961493,0.00020566465,0.0035377466,0.020092439,0.8887155,0.06827339],"study_design_scores_gemma":[0.0002688553,0.00024232184,0.0015158944,0.00018752218,0.000031573498,0.02380036,0.00045449802,0.00068674155,0.0016843464,0.030416906,0.94067824,0.000032863572],"about_ca_topic_score_codex":0.0004337518,"about_ca_topic_score_gemma":0.0005051454,"teacher_disagreement_score":0.005171792,"about_ca_system_score_codex":0.0010153014,"about_ca_system_score_gemma":0.00040691547,"threshold_uncertainty_score":0.013104796},"labels":[],"label_agreement":null},{"id":"W2001370885","doi":"10.1172/jci42004","title":"Lipocalin 2 is essential for chronic kidney disease progression in mice and humans","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Kidney Injury Research","field":"Medicine","cited_by":397,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University Health Network","funders":"National Institutes of Health; Agence Nationale de la Recherche; March of Dimes Foundation","keywords":"Lipocalin; Nephron; Kidney disease; Kidney; Downregulation and upregulation; Cancer research; Renal function; Biology; Urinary system; Medicine; Internal medicine; Endocrinology; Gene","score_opus":0.06965766352198631,"score_gpt":0.4645098004082053,"score_spread":0.39485213688621895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001370885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9322078,0.010628935,0.033575658,0.0027609419,0.0006201027,0.000355349,0.010193094,0.0020300786,0.0076281903],"genre_scores_gemma":[0.9692956,0.003862952,0.011408905,0.00085279654,0.0001047219,0.00058335986,0.004688749,0.00036031113,0.008842719],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993892,0.00008992464,0.000054672866,0.00021693933,0.00015850217,0.00009076079],"domain_scores_gemma":[0.999393,0.000044301712,0.00024401986,0.000064240994,0.00006601074,0.00018841977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053850096,0.0006997742,0.00050493143,0.00085164275,0.000417545,0.00065082056,0.00039285436,0.0010697361,0.0051888954],"category_scores_gemma":[0.00042106523,0.00039756784,0.0005096593,0.00038341348,0.00074495515,0.00044255858,0.00063280325,0.0012921066,0.0011409976],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015060864,0.00012903147,0.0019461336,0.0002415898,0.000054422777,0.0004863816,0.00005747007,0.00013426186,0.98757684,0.0010593332,0.0009996006,0.005808798],"study_design_scores_gemma":[0.0012337388,0.002165406,0.123313285,0.00042450562,0.00049552385,0.0143869715,0.00040336014,0.005451839,0.7281529,0.003505373,0.120298155,0.00016897733],"about_ca_topic_score_codex":0.0010741149,"about_ca_topic_score_gemma":0.0009553718,"teacher_disagreement_score":0.0051888954,"about_ca_system_score_codex":0.00054877676,"about_ca_system_score_gemma":0.00063938886,"threshold_uncertainty_score":0.017358541},"labels":[],"label_agreement":null},{"id":"W2001487688","doi":"10.1172/jci43048","title":"Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Child and Family Research Institute; Children's Hospital of Philadelphia","keywords":"NOD mice; FOXP3; CCL22; Immunology; IL-2 receptor; Pancreatic islets; Chemokine; Immune system; Islet; Autoimmunity; Nod; CD8; Biology; Medicine; T cell; Diabetes mellitus; Endocrinology; CXCL10","score_opus":0.07374213080268871,"score_gpt":0.33624503802602734,"score_spread":0.26250290722333863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001487688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934767,0.0018330751,0.0025657,0.0001842275,0.000074800824,0.000076744655,0.00018364529,0.00019130831,0.0014137577],"genre_scores_gemma":[0.99128854,0.0016873733,0.0032151146,0.00011060308,0.000064689055,0.00013513688,0.0003910621,0.00005169959,0.0030557616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997104,0.000077721816,0.000031395146,0.00004170672,0.0000472944,0.00009150753],"domain_scores_gemma":[0.99981385,0.000024200152,0.00005628309,0.000027106867,0.000013012554,0.000065659675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028405932,0.00061528856,0.0003706303,0.00036404823,0.00020494689,0.0004108507,0.00022937261,0.0002953818,0.0012709566],"category_scores_gemma":[0.00017145673,0.00018361046,0.00024315402,0.00015612283,0.00025516035,0.00020583639,0.0002454879,0.0009887255,0.00034583677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021759087,0.00020395557,0.00017059466,0.00005209531,0.0000046269424,0.00005596062,0.000018784922,0.00012272647,0.9967008,0.00012306354,0.00006453983,0.0022652675],"study_design_scores_gemma":[0.00027696817,0.0025669502,0.002785436,0.000028428562,0.000033500866,0.00044164143,0.000027987979,0.0014460689,0.98772836,0.00007823579,0.0045764563,0.000009985714],"about_ca_topic_score_codex":0.00039463484,"about_ca_topic_score_gemma":0.00076796935,"teacher_disagreement_score":0.0012709566,"about_ca_system_score_codex":0.000218633,"about_ca_system_score_gemma":0.00027693625,"threshold_uncertainty_score":0.004251778},"labels":[],"label_agreement":null},{"id":"W2001712980","doi":"10.1172/jci11476","title":"Increased sensitivity to dextran sodium sulfate colitis in IRE1β-deficient mice","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":401,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; School of Medicine, New York University; National Institutes of Health; Eusko Jaurlaritza; York University; Leukemia and Lymphoma Society","keywords":"Unfolded protein response; Endoplasmic reticulum; Colitis; Inflammatory bowel disease; Inflammation; Gastrointestinal tract; Biology; Immunology; Chemistry; Internal medicine; Medicine; Cell biology; Disease","score_opus":0.03490164561469482,"score_gpt":0.33654496242224446,"score_spread":0.30164331680754963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001712980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931908,0.0012189733,0.0021752995,0.00030175864,0.00007190454,0.000052091928,0.0010093483,0.00036714095,0.0016127302],"genre_scores_gemma":[0.9904687,0.0013454983,0.0021546828,0.00026804928,0.000042830572,0.000072661576,0.0012766991,0.00018065842,0.004190156],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999708,0.00004160175,0.000028811826,0.000102037266,0.000057205194,0.0000622928],"domain_scores_gemma":[0.9994166,0.000049091275,0.00019861707,0.000052660973,0.000037370897,0.000245651],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021207516,0.001097413,0.00071203976,0.0012675438,0.00021841004,0.00057721906,0.00022475257,0.0007722592,0.0032086463],"category_scores_gemma":[0.00034965717,0.00046055016,0.00048030526,0.00029785736,0.00039823493,0.00037721297,0.00030190108,0.0015796428,0.0007539751],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037178083,0.000095819414,0.00067920383,0.000035633177,0.000017689936,0.00029247176,0.000028818396,0.00007896214,0.99696606,0.00006277599,0.000106579326,0.0012641795],"study_design_scores_gemma":[0.0004002101,0.004913623,0.109180115,0.00014271626,0.00021262752,0.011448658,0.00018805446,0.0030599113,0.86305773,0.0006935487,0.006616617,0.00008611616],"about_ca_topic_score_codex":0.00038930535,"about_ca_topic_score_gemma":0.00046288632,"teacher_disagreement_score":0.0032086463,"about_ca_system_score_codex":0.00035273828,"about_ca_system_score_gemma":0.0001531198,"threshold_uncertainty_score":0.010733962},"labels":[],"label_agreement":null},{"id":"W2001882980","doi":"10.1172/jci31368","title":"Priming and effector dependence on insulin B:9–23 peptide in NOD islet autoimmunity","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of California, San Francisco; National Institutes of Health; American Diabetes Association","keywords":"Autoimmunity; Effector; Islet; Nod; Priming (agriculture); Insulin; Endocrinology; Biology; Internal medicine; Immunology; Medicine; Diabetes mellitus; Immune system","score_opus":0.03243182464320188,"score_gpt":0.3399398233937225,"score_spread":0.3075079987505206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001882980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964141,0.0007580878,0.00094632234,0.00003707842,0.000014595365,0.000020936983,0.00010753294,0.000056634704,0.0016448123],"genre_scores_gemma":[0.9977076,0.00041459,0.00076408515,0.000045429093,0.000009262918,0.000032815944,0.00015036397,0.000015481623,0.000860212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986184,0.000024839583,0.00001751482,0.000030423818,0.000022276423,0.00004312475],"domain_scores_gemma":[0.99977535,0.000035358826,0.00006221957,0.000029714382,0.0000141804485,0.00008323819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017607652,0.00040502555,0.00017430402,0.0001628564,0.00012445169,0.00028910654,0.000163652,0.00023936464,0.0012863611],"category_scores_gemma":[0.00014248701,0.00015602996,0.00020657526,0.00007577292,0.00017427177,0.00023222959,0.00027909543,0.0006664164,0.0005241108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020551845,0.000046751295,0.00045395328,0.000024429706,0.0000015271696,0.00007870175,0.000008092668,0.00003841434,0.99843556,0.000052322524,0.00000881356,0.00064582564],"study_design_scores_gemma":[0.000060238122,0.0010065542,0.014224794,0.000024835264,0.000023769953,0.0011189104,0.000036508536,0.0006361281,0.9814618,0.00012780058,0.0012700034,0.000008694683],"about_ca_topic_score_codex":0.00012659028,"about_ca_topic_score_gemma":0.00016870085,"teacher_disagreement_score":0.0012863611,"about_ca_system_score_codex":0.00016374847,"about_ca_system_score_gemma":0.00014888048,"threshold_uncertainty_score":0.0043032765},"labels":[],"label_agreement":null},{"id":"W2003651863","doi":"10.1172/jci45114","title":"Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Canada Research Chairs; Multiple Sclerosis Society of Canada; National Institutes of Health; University of Calgary","keywords":"Biology; Lamina propria; Cytokine; Immunology; Hyperplasia; FOXP3; Cancer research; T cell; Interleukin 17; Epithelium; Endocrinology; Immune system","score_opus":0.125790722975281,"score_gpt":0.32121663798634276,"score_spread":0.19542591501106177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003651863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98822254,0.0015763784,0.0053663403,0.00038187014,0.00009791004,0.00014615234,0.0011604242,0.000379282,0.0026691142],"genre_scores_gemma":[0.9778581,0.0018431814,0.0066526528,0.00024694632,0.000044422297,0.00027537503,0.0010979248,0.0001616179,0.01181971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995365,0.000106293286,0.000056616762,0.00009252155,0.00009558585,0.000112527385],"domain_scores_gemma":[0.9994555,0.00006351446,0.00021624088,0.000048115453,0.00003306211,0.0001836657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034998002,0.0010588045,0.00036047472,0.0014319583,0.00034509425,0.00050535565,0.00035992067,0.00092442654,0.0033772322],"category_scores_gemma":[0.00022109383,0.0006039692,0.0005789279,0.00028221373,0.0006885172,0.00035397997,0.0003986337,0.0016624985,0.0008160142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005870414,0.00014746498,0.00040339105,0.00006688015,0.0000146999155,0.00020485086,0.000031152562,0.000091064365,0.9969887,0.00022831459,0.000064674874,0.0011718461],"study_design_scores_gemma":[0.00020360571,0.0011251487,0.0050488263,0.000037171056,0.00005407918,0.0007174957,0.00009125867,0.0014386082,0.9873347,0.00019592598,0.0037412287,0.00001193417],"about_ca_topic_score_codex":0.0005032346,"about_ca_topic_score_gemma":0.0011627066,"teacher_disagreement_score":0.0033772322,"about_ca_system_score_codex":0.00042135554,"about_ca_system_score_gemma":0.00040965006,"threshold_uncertainty_score":0.011297941},"labels":[],"label_agreement":null},{"id":"W2003926050","doi":"10.1172/jci16409","title":"Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood","year":2003,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":211,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Simon Fraser University; University of Alberta; BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia; Fondation pour la Recherche Médicale; Children's Hospital Foundation; Michael Smith Health Research BC; Canadian Diabetes Association","keywords":"Immunology; Autoimmune diabetes; Autoimmunity; Peripheral blood; Type 1 diabetes; NOD mice; Major histocompatibility complex; Nod; Diabetes mellitus; Medicine; Avidity; Autoimmune disease; Peripheral; Antigen; Immune system; Endocrinology; Internal medicine; Antibody","score_opus":0.022124494155687322,"score_gpt":0.27187524140276176,"score_spread":0.24975074724707444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003926050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90967226,0.0045215576,0.015387249,0.033182137,0.0029833016,0.00029058248,0.0007824491,0.0010053738,0.03217508],"genre_scores_gemma":[0.9750759,0.0022146066,0.0055010403,0.0067457194,0.0020216615,0.00015334827,0.0004322907,0.00008625652,0.007769275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899215,0.00045633686,0.00011011728,0.00013065695,0.00023432795,0.00007629297],"domain_scores_gemma":[0.9978771,0.0013155104,0.00018502797,0.00027009152,0.00017318,0.00017907444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012243113,0.00058296585,0.00045889933,0.00047617624,0.0002975091,0.0005668249,0.0003761499,0.0021793894,0.0013004935],"category_scores_gemma":[0.0037491356,0.00025287364,0.00019465642,0.00019767578,0.0004947218,0.00039470277,0.00018920112,0.0018390986,0.0010228612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014056573,0.0023842268,0.14664623,0.00078961294,0.00021334448,0.13548459,0.00060811784,0.0018629892,0.45337936,0.008617407,0.050896794,0.18506081],"study_design_scores_gemma":[0.003284594,0.008321233,0.17904082,0.0005546496,0.00028421156,0.3705668,0.00036897755,0.047244325,0.2812266,0.018967533,0.0899399,0.00020043502],"about_ca_topic_score_codex":0.00015788215,"about_ca_topic_score_gemma":0.0001790727,"teacher_disagreement_score":0.0021793894,"about_ca_system_score_codex":0.0004727359,"about_ca_system_score_gemma":0.000116211086,"threshold_uncertainty_score":0.0064748526},"labels":[],"label_agreement":null},{"id":"W2004582153","doi":"10.1172/jci27208","title":"Desperately seeking sugar: glial cells as hypoglycemia sensors","year":2005,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation","funders":"Hospital for Sick Children","keywords":"GLUT2; Hypoglycemia; Glucagon; Glucose transporter; Secretion; Endocrinology; Internal medicine; Biology; Chemistry; Cell biology; Medicine; Diabetes mellitus; Insulin","score_opus":0.08464861577158506,"score_gpt":0.36111188110018966,"score_spread":0.2764632653286046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004582153","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007304533,0.017701153,0.000591382,0.9426851,0.026497768,0.00002621009,0.000042922664,0.00008971431,0.0050613163],"genre_scores_gemma":[0.06591576,0.025913611,0.0012014534,0.7617472,0.13397352,0.00010056375,0.000044757315,0.00003302937,0.011070113],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993253,0.00025555142,0.000084783715,0.00007636646,0.00016602299,0.00009195263],"domain_scores_gemma":[0.9987692,0.0007064106,0.00010543099,0.00007190064,0.00017016323,0.00017676821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010320172,0.000886913,0.0010162106,0.0003649199,0.001311463,0.0019171078,0.0010441248,0.018053886,0.0018274531],"category_scores_gemma":[0.004297121,0.0004472986,0.00060743815,0.00029794965,0.001858272,0.0025903212,0.0007254833,0.014916688,0.0025244036],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000645319,0.00017926734,0.0027498014,0.00034921116,0.000057452675,0.042171877,0.000421994,0.00018196904,0.004163083,0.00999717,0.8639645,0.07511833],"study_design_scores_gemma":[0.0010221277,0.00057138235,0.004755042,0.00053391274,0.00014290419,0.07407288,0.0014335046,0.0016424527,0.0038873572,0.0337349,0.878083,0.00012051172],"about_ca_topic_score_codex":0.00061704655,"about_ca_topic_score_gemma":0.0012396045,"teacher_disagreement_score":0.018053886,"about_ca_system_score_codex":0.0014501509,"about_ca_system_score_gemma":0.0005635929,"threshold_uncertainty_score":0.01052165},"labels":[],"label_agreement":null},{"id":"W2005785099","doi":"10.1172/jci35754","title":"Platelet glycoprotein Ibα forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":284,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Georgia Institute of Technology; American Heart Association","keywords":"Von Willebrand disease; Von Willebrand factor; Platelet; Chemistry; Platelet Glycoprotein GPIb-IX Complex; Platelet membrane glycoprotein; Platelet adhesiveness; Mutant; Glycoprotein Ib; ADAMTS13; Thrombospondin; Glycoprotein; Biophysics; Metalloproteinase; Immunology; Biochemistry; Biology; Platelet aggregation","score_opus":0.06294040595608047,"score_gpt":0.3417059067807617,"score_spread":0.2787655008246812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005785099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99798393,0.0003863631,0.0010930973,0.000028173352,0.000008385519,0.000008929617,0.00005447907,0.000018540133,0.00041816052],"genre_scores_gemma":[0.9980882,0.00012474292,0.00080885534,0.000036695623,0.000002973024,0.000008778355,0.00023298133,0.0000143896295,0.0006823907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986494,0.000016527762,0.000010196597,0.000029473078,0.000053404492,0.000025348885],"domain_scores_gemma":[0.999908,0.000013309554,0.000038883696,0.000011720698,0.0000075011535,0.000020664273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014721177,0.0002474017,0.00015759216,0.00008415727,0.0001225725,0.00022110606,0.00013907597,0.00021911798,0.00078319915],"category_scores_gemma":[0.00022960367,0.000163528,0.00019798118,0.0000783313,0.00014129368,0.00014998236,0.00011717214,0.00024279377,0.00021973287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001519947,0.000034876128,0.0016058433,0.000022898512,0.000036036094,0.00009016112,0.000027550137,0.0002826881,0.9958603,0.00024262891,0.00009468956,0.0015503598],"study_design_scores_gemma":[0.000074757,0.0005269545,0.01936234,0.000009842881,0.00004349104,0.001405964,0.00002663208,0.0052711233,0.9692821,0.00018460378,0.0037987102,0.000013573424],"about_ca_topic_score_codex":0.00064135925,"about_ca_topic_score_gemma":0.0005151692,"teacher_disagreement_score":0.00078319915,"about_ca_system_score_codex":0.00026991163,"about_ca_system_score_gemma":0.00010338891,"threshold_uncertainty_score":0.002620101},"labels":[],"label_agreement":null},{"id":"W2006030544","doi":"10.1172/jci66387","title":"Giant axonal neuropathy–associated gigaxonin mutations impair intermediate filament protein degradation","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"Intermediate filament; Neurofilament; Vimentin; Peripherin; Cell biology; Signal transducing adaptor protein; Mutation; Ubiquitin ligase; Cytoskeleton; Biology; Proteasome; Ubiquitin; Aggresome; Gene; Molecular biology; Cell; Phosphorylation; Genetics; Immunology; Immunohistochemistry","score_opus":0.04955218141148766,"score_gpt":0.34514360424038487,"score_spread":0.2955914228288972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006030544","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975616,0.0005963899,0.0004987764,0.00003322432,0.00000973336,0.000011967089,0.00014241818,0.00003371118,0.0011121223],"genre_scores_gemma":[0.9985214,0.00020592222,0.0004134617,0.000033839297,0.0000034563943,0.000007067484,0.00020262532,0.000008147458,0.00060404313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993,0.000012976354,0.000009769075,0.000013483188,0.000012581025,0.000021084486],"domain_scores_gemma":[0.9999207,0.000015995845,0.000022928923,0.000008574542,0.0000055808437,0.000026216212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000847551,0.00042491578,0.00022475299,0.0001970604,0.00010174192,0.00018682869,0.00011916292,0.0002883086,0.0011183386],"category_scores_gemma":[0.00012238343,0.00009325969,0.00020642739,0.00009033637,0.0001704882,0.00016055792,0.00018469772,0.00022510254,0.00029176535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001744685,0.000027656071,0.0006486283,0.000031921983,0.000010506926,0.000557327,0.000006613768,0.000049991304,0.99720615,0.00006483363,0.000041228574,0.00118063],"study_design_scores_gemma":[0.000104680854,0.00078068825,0.06509786,0.000021476342,0.000065285334,0.011426185,0.00005438691,0.0010910805,0.9181037,0.00029606375,0.00294443,0.000014174432],"about_ca_topic_score_codex":0.00027217745,"about_ca_topic_score_gemma":0.00049030164,"teacher_disagreement_score":0.0011183386,"about_ca_system_score_codex":0.00018833719,"about_ca_system_score_gemma":0.00007348327,"threshold_uncertainty_score":0.0037412047},"labels":[],"label_agreement":null},{"id":"W2006306072","doi":"10.1172/jci27540","title":"Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":337,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of General Medical Sciences; Heart and Stroke Foundation of Canada; National Institutes of Health; Pfizer","keywords":"Prostacyclin; Prostaglandin; Prostaglandin H2; Thromboxane; Thromboxane A2; Thromboxane-A synthase; Aspirin; ATP synthase; Enzyme; Microsome; Pharmacology; Knockout mouse; Cyclooxygenase; Adverse effect; Internal medicine; Endocrinology; Medicine; Chemistry; Receptor; Platelet; Biochemistry","score_opus":0.028102003048913814,"score_gpt":0.29972253915709063,"score_spread":0.2716205361081768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006306072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6768454,0.3092817,0.005241725,0.0016472911,0.0002746352,0.00005310785,0.00045230874,0.000053317188,0.0061505684],"genre_scores_gemma":[0.9394185,0.05603595,0.0017430156,0.00024773163,0.00018232525,0.000029293533,0.0002114661,0.0000029542987,0.0021288241],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999354,0.00001792137,0.0000038336366,0.000015026394,0.000012029567,0.000015848498],"domain_scores_gemma":[0.9998852,0.000025572957,0.00004261239,0.000006893629,0.00001303701,0.000026736257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019907964,0.00028350146,0.00017991012,0.00024174049,0.00012473339,0.0003027274,0.00011344934,0.00033949965,0.0007200008],"category_scores_gemma":[0.00017249375,0.00007428343,0.00015022681,0.0001549283,0.0002494938,0.000252338,0.00013333975,0.00049362803,0.00010831634],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020364244,0.0003046749,0.023861198,0.0011126364,0.00013580215,0.0008664023,0.000104441955,0.000985958,0.8839901,0.007661225,0.0010489739,0.07789204],"study_design_scores_gemma":[0.00015327697,0.0056209033,0.3864886,0.00029963016,0.0003933114,0.0049256636,0.0003268222,0.0042410516,0.5368233,0.010891393,0.04976056,0.000075465316],"about_ca_topic_score_codex":0.00044457463,"about_ca_topic_score_gemma":0.00074687833,"teacher_disagreement_score":0.0007200008,"about_ca_system_score_codex":0.0002555002,"about_ca_system_score_gemma":0.00023895166,"threshold_uncertainty_score":0.0024086237},"labels":[],"label_agreement":null},{"id":"W2007251599","doi":"10.1172/jci58818","title":"TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":174,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Toronto; BC Cancer Agency","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Lung cancer; Carcinogenesis; Oncogene; Biology; Cancer research; Somatic cell; Cancer; Gene duplication; Gene; Genetics; Pathology; Medicine; Cell cycle","score_opus":0.1693963742779293,"score_gpt":0.38861740340011813,"score_spread":0.21922102912218883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007251599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871111,0.008344593,0.0021445092,0.00018786191,0.000016952134,0.000025724898,0.0004862898,0.00007856227,0.0016044701],"genre_scores_gemma":[0.9949588,0.002209576,0.0011858045,0.000017658764,0.000009885126,0.0000067795786,0.00041328947,0.0000034625907,0.0011948417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999249,0.000011480752,0.000007979819,0.000014983551,0.000026002655,0.000014691305],"domain_scores_gemma":[0.99994814,0.000006408091,0.00001820372,0.0000058869155,0.000007994934,0.00001333433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001359094,0.00022543634,0.00012071041,0.0003798476,0.00017808324,0.00026701298,0.000102971346,0.00023062697,0.0010833106],"category_scores_gemma":[0.00014647946,0.00010505575,0.0001221358,0.00033831937,0.00019077188,0.00014025258,0.00014193321,0.0002634452,0.0004656687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023396083,0.000026332369,0.002374429,0.000063249565,0.0000075411276,0.00032273325,0.000015836522,0.00008576033,0.99145985,0.00018338543,0.000055127966,0.005171773],"study_design_scores_gemma":[0.00004441086,0.00065061613,0.06663482,0.000018188743,0.00005590486,0.01614363,0.000073434414,0.0012109142,0.90314007,0.0006276529,0.011387062,0.000013378912],"about_ca_topic_score_codex":0.0004560446,"about_ca_topic_score_gemma":0.00046016308,"teacher_disagreement_score":0.0010833106,"about_ca_system_score_codex":0.00026163223,"about_ca_system_score_gemma":0.00018370169,"threshold_uncertainty_score":0.003624022},"labels":[],"label_agreement":null},{"id":"W2007349210","doi":"10.1172/jci32214","title":"Murine models of Omenn syndrome","year":2007,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Immunology; Severe combined immunodeficiency; Immunodeficiency; Autoimmunity; Disease; Wiskott–Aldrich syndrome; RAG2; Immunodeficiency Syndrome; Immune dysregulation; Medicine; Pathogenesis; Biology; Immune system; Genetics; Pathology","score_opus":0.18942067401908494,"score_gpt":0.42081014405881223,"score_spread":0.2313894700397273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007349210","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0020558967,0.98801243,0.0018583889,0.0006172663,0.00063712255,0.000034703367,0.00009124792,0.00011041125,0.0065825316],"genre_scores_gemma":[0.011255967,0.9806841,0.0015952652,0.0008531107,0.00025560465,0.0000745742,0.00028233367,0.000010779239,0.004988231],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997738,0.00003597006,0.000018857865,0.000033520268,0.00010955512,0.000028404284],"domain_scores_gemma":[0.9998796,0.000028108456,0.000026450187,0.000007740965,0.000030829942,0.0000272025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005673644,0.0012782887,0.0013131347,0.0014743346,0.00024216402,0.00071515405,0.0011708746,0.0013932461,0.0020446223],"category_scores_gemma":[0.00024917716,0.00021410361,0.00029950752,0.000751451,0.00048306314,0.00072960585,0.0005420909,0.0019725338,0.0021765365],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043999907,0.0004005704,0.00053853827,0.009139461,0.0001296064,0.0021532227,0.00013710604,0.0010125723,0.1413144,0.015506395,0.059837893,0.7693902],"study_design_scores_gemma":[0.000067108725,0.000325359,0.0010122872,0.001039884,0.00008108888,0.0043396344,0.000042346943,0.0001712046,0.014178588,0.003324034,0.97538584,0.000032628668],"about_ca_topic_score_codex":0.00045741425,"about_ca_topic_score_gemma":0.0008029454,"teacher_disagreement_score":0.0020446223,"about_ca_system_score_codex":0.0006729301,"about_ca_system_score_gemma":0.00039513383,"threshold_uncertainty_score":0.006839931},"labels":[],"label_agreement":null},{"id":"W2007770885","doi":"10.1172/jci34088","title":"Mutations in the nervous system–specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Sensory system; Nervous system; Biology; Exon; Peripheral nervous system; Neuroscience; Sensory neuron; Point mutation; Gene isoform; Hereditary motor and sensory neuropathy; Genetics; Mutation; Central nervous system; Gene","score_opus":0.09290392131071465,"score_gpt":0.3202977262753699,"score_spread":0.22739380496465525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007770885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99545246,0.0005299207,0.0010741671,0.00010209322,0.000038217913,0.000040544095,0.0003642677,0.00006820224,0.002330202],"genre_scores_gemma":[0.9954268,0.00032383515,0.00094699586,0.00010374576,0.000015426916,0.000016984586,0.0004405095,0.000021050713,0.0027046038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993086,0.0000055740647,0.0000049571936,0.000020526824,0.000023471046,0.000014535334],"domain_scores_gemma":[0.99991333,0.000009101026,0.000032745535,0.000003474481,0.000010119135,0.000031161908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064471526,0.0007453336,0.00019206408,0.00026544,0.00023014021,0.00015834121,0.00018427098,0.000304227,0.0012541267],"category_scores_gemma":[0.0001800263,0.00012989501,0.0001599432,0.000140616,0.00035655248,0.00007790557,0.00019912064,0.0002555319,0.00031656484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047992813,0.000102878104,0.021556975,0.00014907347,0.00008029748,0.03833976,0.00024538222,0.0003989611,0.93022984,0.00037350864,0.0010947224,0.0069486285],"study_design_scores_gemma":[0.00020676493,0.00056951883,0.6338437,0.0001306308,0.00018645803,0.11178795,0.00028572825,0.002943434,0.23337142,0.00027936077,0.016336842,0.000058217476],"about_ca_topic_score_codex":0.008359138,"about_ca_topic_score_gemma":0.018914139,"teacher_disagreement_score":0.008359138,"about_ca_system_score_codex":0.00062357757,"about_ca_system_score_gemma":0.0003602219,"threshold_uncertainty_score":0.016620934},"labels":[],"label_agreement":null},{"id":"W2009878875","doi":"10.1172/jci33296","title":"Cholesterol in islet dysfunction and type 2 diabetes","year":2008,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Killam Trusts; Michael Smith Health Research BC; Child and Family Research Institute","keywords":"Endocrinology; Islet; Internal medicine; Type 2 diabetes; ABCA1; Cholesterol; Diabetes mellitus; Context (archaeology); Insulin; Biology; Reverse cholesterol transport; Glucose homeostasis; Homeostasis; Pancreas; Insulin resistance; Medicine; Transporter; Lipoprotein; Gene; Biochemistry","score_opus":0.15060970827892547,"score_gpt":0.4193056563157181,"score_spread":0.26869594803679264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009878875","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000051579806,0.9988906,0.000045812987,0.000203768,0.0002910475,0.0000019645574,0.0000058141286,0.000004261227,0.00050522963],"genre_scores_gemma":[0.00037323183,0.99849844,0.00009929441,0.00019951946,0.00034124515,0.0000029718562,0.000011261518,8.9811675e-7,0.0004731175],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997811,0.00004124041,0.000034776232,0.000035403027,0.00008969494,0.000017721099],"domain_scores_gemma":[0.99970514,0.000106350664,0.000047074875,0.000009418485,0.0000950508,0.000036843016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005655988,0.0009446843,0.0016278792,0.0025652277,0.00033710897,0.00089231884,0.00078845257,0.0014136395,0.002870296],"category_scores_gemma":[0.00069957646,0.00026618206,0.00036328362,0.0031458565,0.0005530445,0.0012966642,0.0007007335,0.001766078,0.003206608],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093361225,0.00006144901,0.0002837082,0.010700243,0.00006491863,0.0005532482,0.000057859444,0.00021999907,0.0010950817,0.0022340133,0.05797362,0.92666245],"study_design_scores_gemma":[0.000023194778,0.00007382048,0.0013085261,0.003481454,0.00008037116,0.0037601797,0.0000670959,0.00005520116,0.00021628768,0.001826261,0.98908967,0.00001788578],"about_ca_topic_score_codex":0.001258069,"about_ca_topic_score_gemma":0.00203728,"teacher_disagreement_score":0.002870296,"about_ca_system_score_codex":0.0006424041,"about_ca_system_score_gemma":0.0009453263,"threshold_uncertainty_score":0.00960207},"labels":[],"label_agreement":null},{"id":"W2009926432","doi":"10.1172/jci23334","title":"Glycyrrhizic acid alters Kaposi sarcoma–associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Center for AIDS Research, University of Washington; York University; National Institute of Allergy and Infectious Diseases; Elsa U. Pardee Foundation","keywords":"Apoptosis; Latency (audio); Virology; Sarcoma; Cancer research; Biology; Medicine; Immunology; Genetics; Pathology; Computer science","score_opus":0.04118993239321012,"score_gpt":0.3124120277157193,"score_spread":0.2712220953225092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009926432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983144,0.0006240565,0.0003375075,0.000035230034,0.000012747237,0.00001007165,0.000054715834,0.000025056279,0.0005862806],"genre_scores_gemma":[0.998453,0.00045955752,0.00040515626,0.00002105244,0.0000045480183,0.000008559768,0.00007166623,0.000005229877,0.0005711559],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992776,0.000019078238,0.000005940462,0.0000082594315,0.000014366934,0.000024478608],"domain_scores_gemma":[0.9999466,0.000009263045,0.000015201835,0.000008224804,0.000004595881,0.000015964984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009554447,0.00023202928,0.00015889222,0.00015508807,0.000102720085,0.0001889363,0.00011263508,0.00022654839,0.0006502706],"category_scores_gemma":[0.00009212496,0.00008727991,0.00013767577,0.00008827202,0.0001645955,0.00014346588,0.000098860895,0.00041727244,0.00016286012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027311002,0.00007090373,0.00007542518,0.0000131127945,0.000003479346,0.00003294114,0.000005334567,0.00002754452,0.9984042,0.00003246144,0.00001082449,0.0010507557],"study_design_scores_gemma":[0.00013424615,0.002484715,0.0046802005,0.000004665817,0.000032024094,0.00035192608,0.000027096972,0.0006124631,0.9905048,0.00010310537,0.0010610113,0.0000037887053],"about_ca_topic_score_codex":0.00023779598,"about_ca_topic_score_gemma":0.00025960908,"teacher_disagreement_score":0.0006502706,"about_ca_system_score_codex":0.00013782222,"about_ca_system_score_gemma":0.0001270492,"threshold_uncertainty_score":0.002175331},"labels":[],"label_agreement":null},{"id":"W2010027879","doi":"10.1172/jci19796","title":"15-deoxy-Δ12,14-PGJ2: endogenous PPARγ ligand or minor eicosanoid degradation product?","year":2003,"lang":"nl","type":"letter","venue":"Journal of Clinical Investigation","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Transcription factor; Endogeny; Eicosanoid; Transcription (linguistics); Cell biology; Chemistry; Prostaglandin E2 receptor; Biology; Prostaglandin; Biochemistry; Receptor; Gene; Enzyme","score_opus":0.0902799630931075,"score_gpt":0.33308629960549363,"score_spread":0.24280633651238615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010027879","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010599037,0.0044582817,0.0010043725,0.94940054,0.019593162,0.00007246633,0.00018649545,0.0001249135,0.014560694],"genre_scores_gemma":[0.16885498,0.01474625,0.0028790704,0.6491865,0.08272074,0.00028472982,0.0003782695,0.000096230426,0.080853276],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996413,0.00012288516,0.000037203332,0.000059250164,0.00008056447,0.000058838436],"domain_scores_gemma":[0.99901676,0.0005800131,0.00008451597,0.00005096719,0.00013392205,0.00013365108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005487012,0.0006068644,0.00063856546,0.00023326813,0.0006448135,0.001169317,0.0006165234,0.0089401975,0.0070989253],"category_scores_gemma":[0.0040211105,0.00024665956,0.00043002426,0.00019310671,0.0012708658,0.00093415496,0.00022479711,0.0060644993,0.005902957],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023103368,0.0004168221,0.0053364043,0.00052156876,0.00006075748,0.064481944,0.00022720968,0.00043439702,0.01121693,0.012178801,0.81676626,0.08604844],"study_design_scores_gemma":[0.0010934932,0.0009453251,0.005421874,0.00035825482,0.00010108351,0.061009556,0.00058349565,0.0023574242,0.009135367,0.02357761,0.8953507,0.00006579575],"about_ca_topic_score_codex":0.0009027205,"about_ca_topic_score_gemma":0.00095927104,"teacher_disagreement_score":0.0089401975,"about_ca_system_score_codex":0.0023000424,"about_ca_system_score_gemma":0.00058339414,"threshold_uncertainty_score":0.023748219},"labels":[],"label_agreement":null},{"id":"W2010433305","doi":"10.1172/jci76737","title":"Cardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; American Heart Association; Robert H. Lurie Comprehensive Cancer Center; National Cancer Institute; National Institutes of Health; Northwestern University","keywords":"Aryl hydrocarbon receptor nuclear translocator; Lipotoxicity; Internal medicine; Diabetic cardiomyopathy; Endocrinology; Biology; Beta oxidation; Steatosis; Gene knockdown; Cardiomyopathy; Medicine; Diabetes mellitus; Heart failure; Gene; Aryl hydrocarbon receptor; Transcription factor; Metabolism; Insulin resistance; Biochemistry","score_opus":0.03712460528525551,"score_gpt":0.32345176136852183,"score_spread":0.2863271560832663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010433305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939442,0.0010940749,0.0032501586,0.0001469045,0.0000468951,0.00002274064,0.00014376406,0.00012282857,0.0012283853],"genre_scores_gemma":[0.9950706,0.000903237,0.0013822551,0.00014636898,0.00002187644,0.00003309553,0.0002799938,0.000035733032,0.0021268607],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998574,0.000028145252,0.000013841687,0.000035888082,0.00003347643,0.000031256684],"domain_scores_gemma":[0.99986887,0.000028649174,0.000041860625,0.000012897146,0.0000064918804,0.00004129118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016629467,0.0004499871,0.00028783895,0.00025383334,0.00017066077,0.00022491698,0.00014347135,0.0002915679,0.00140699],"category_scores_gemma":[0.00015280912,0.00019597735,0.0002852377,0.0001414622,0.00035850244,0.00013978181,0.00022017055,0.0005999797,0.0003082981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028127906,0.000057881203,0.00046986458,0.000024763334,0.0000107654,0.00026205168,0.000012694035,0.000106032945,0.9963726,0.00014688248,0.00006155924,0.0021936484],"study_design_scores_gemma":[0.00023596059,0.0022472187,0.027306397,0.000029851022,0.00011498935,0.005412526,0.00011227636,0.003513872,0.95443887,0.00047952778,0.0060892426,0.000019217969],"about_ca_topic_score_codex":0.00020672756,"about_ca_topic_score_gemma":0.00039875894,"teacher_disagreement_score":0.00140699,"about_ca_system_score_codex":0.00015308462,"about_ca_system_score_gemma":0.0001630587,"threshold_uncertainty_score":0.0047068596},"labels":[],"label_agreement":null},{"id":"W2010895111","doi":"10.1172/jci21047","title":"Splanchnic lipolysis in human obesity","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":891,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; Deutsches Krebsforschungszentrum; Mayo Foundation for Medical Education and Research; Mayo Clinic","keywords":"Lipolysis; Splanchnic; Internal medicine; Adipose tissue; Endocrinology; Medicine; Obesity; Splanchnic Circulation; Intra-Abdominal Fat; Visceral fat; Hemodynamics; Insulin resistance","score_opus":0.09105230251329119,"score_gpt":0.41034344818866025,"score_spread":0.3192911456753691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010895111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94832927,0.040460877,0.0051715677,0.00036925526,0.00003597838,0.000046173813,0.00025240562,0.00009063148,0.0052437778],"genre_scores_gemma":[0.9914408,0.006022858,0.0013935834,0.00010759697,0.000031236836,0.000027853665,0.0001818183,0.0000097551365,0.0007845024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999044,0.000041272568,0.000006893636,0.000017011076,0.000020206355,0.000010164056],"domain_scores_gemma":[0.999905,0.000020107369,0.00003890298,0.00001242858,0.000009644878,0.000013908069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033413363,0.00030363502,0.00020990852,0.0004849348,0.00010160426,0.00030319736,0.00007636513,0.00017004095,0.0009562018],"category_scores_gemma":[0.00045729394,0.00013734639,0.00010417548,0.0003915818,0.0002509285,0.0001460524,0.0002510448,0.00031788982,0.00025608722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011282781,0.00031683687,0.2377307,0.0007653017,0.0002660452,0.005042817,0.0004918233,0.0016771014,0.5045646,0.0034413855,0.0013686405,0.23305203],"study_design_scores_gemma":[0.00017047313,0.002049079,0.92608404,0.00011333422,0.00015964544,0.017955374,0.0001572161,0.001978398,0.040258344,0.0030113263,0.00803072,0.000032214975],"about_ca_topic_score_codex":0.00053251826,"about_ca_topic_score_gemma":0.0002996095,"teacher_disagreement_score":0.0009562018,"about_ca_system_score_codex":0.00021495538,"about_ca_system_score_gemma":0.00012757232,"threshold_uncertainty_score":0.003198862},"labels":[],"label_agreement":null},{"id":"W2011319917","doi":"10.1172/jci31772","title":"TNF-α induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; National Cancer Institute; Cincinnati Children's Hospital Medical Center; National Institutes of Health; University of California, San Diego; University of Toronto; Hospital for Sick Children; Oregon Health and Science University","keywords":"Fanconi anemia; Stem cell; Biology; Haematopoiesis; Leukemia; Cancer research; Cytokine; Immunology; Myeloid leukemia; Molecular biology; Cell biology; DNA repair; Genetics; Gene","score_opus":0.03744131898778438,"score_gpt":0.3246957050305218,"score_spread":0.28725438604273745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011319917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736744,0.0005807068,0.0009114362,0.000041199393,0.000023034916,0.000046969093,0.00017169476,0.000057232268,0.0008002951],"genre_scores_gemma":[0.997401,0.0003802726,0.00081916084,0.000041980547,0.000012035741,0.000036821886,0.00033826174,0.00001252418,0.0009580857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979717,0.0000579162,0.000023036924,0.000024209905,0.000049617076,0.0000480907],"domain_scores_gemma":[0.9997712,0.000054749136,0.000064187516,0.00003724072,0.000019501254,0.00005304131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026081133,0.0003312954,0.00025596202,0.0002544311,0.00012430345,0.00024428382,0.00012366491,0.00024126914,0.00064637733],"category_scores_gemma":[0.0001580739,0.00012493967,0.00015562463,0.0001671246,0.0001759659,0.000129085,0.0001354651,0.0006121478,0.0002447293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017341612,0.00010396917,0.00027560952,0.000015534122,0.0000042584647,0.000054974545,0.000019020685,0.00007021575,0.998049,0.000042837455,0.000035731195,0.0011552478],"study_design_scores_gemma":[0.000065473396,0.001530191,0.0036879366,0.0000066145026,0.0000152061675,0.00030735077,0.000023451206,0.00086297636,0.99232084,0.000031471664,0.0011459596,0.0000024652861],"about_ca_topic_score_codex":0.00032877887,"about_ca_topic_score_gemma":0.00065946754,"teacher_disagreement_score":0.00064637733,"about_ca_system_score_codex":0.0002546522,"about_ca_system_score_gemma":0.00015817568,"threshold_uncertainty_score":0.0021623373},"labels":[],"label_agreement":null},{"id":"W2013845729","doi":"10.1172/jci59763","title":"Informed reasoning: repositioning of nitisinone to treat oculocutaneous albinism","year":2011,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; School of Medicine, New York University; York University","keywords":"Oculocutaneous albinism; Hypopigmentation; Albinism; Melanin; Medicine; Dermatology; Genetics; Biology","score_opus":0.0578510486069856,"score_gpt":0.3551206380726573,"score_spread":0.2972695894656717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013845729","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0055071483,0.003323387,0.000707401,0.9582357,0.020050293,0.00007182466,0.00009625025,0.00014420172,0.011863855],"genre_scores_gemma":[0.043562654,0.0048153475,0.0020931792,0.88690704,0.045612473,0.00011756488,0.000120853634,0.00005604582,0.016714863],"study_design_codex":"not_applicable","study_design_gemma":"case_report","domain_scores_codex":[0.9990219,0.00031627872,0.00012223658,0.00013447217,0.00026948153,0.00013564387],"domain_scores_gemma":[0.9985783,0.0008005468,0.000076620025,0.000060385148,0.00027301858,0.00021100763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086714275,0.0006999296,0.00076325884,0.0005160248,0.0013462796,0.0012914392,0.0013252333,0.022314468,0.0056210547],"category_scores_gemma":[0.009320455,0.00032540914,0.0010321465,0.00041440994,0.0013546583,0.002362463,0.00059576833,0.015363176,0.004154849],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031201495,0.00029439328,0.0026374653,0.00017599616,0.00005636345,0.0669537,0.00033471987,0.00062712055,0.0018941988,0.0073313178,0.8697169,0.049665924],"study_design_scores_gemma":[0.00085691916,0.00071273546,0.004079938,0.0006571969,0.000119724406,0.15635325,0.0008064702,0.0072326665,0.0029965232,0.028219005,0.7977808,0.000184691],"about_ca_topic_score_codex":0.0016954214,"about_ca_topic_score_gemma":0.0022969916,"teacher_disagreement_score":0.022314468,"about_ca_system_score_codex":0.0024417383,"about_ca_system_score_gemma":0.0012016635,"threshold_uncertainty_score":0.018804252},"labels":[],"label_agreement":null},{"id":"W2013908114","doi":"10.1172/jci64840","title":"Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":326,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Harvard NeuroDiscovery Center","keywords":"Cathepsin K; Osteoclast; Bone resorption; Osteoblast; Endocrinology; RANKL; Internal medicine; Biology; Bone remodeling; Resorption; Cathepsin; Sphingosine; Cell biology; Chemistry; Receptor; Biochemistry; Medicine; In vitro","score_opus":0.0439522180613512,"score_gpt":0.3193938105348186,"score_spread":0.2754415924734674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013908114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937551,0.0021816131,0.00118582,0.00019149155,0.000043196662,0.000060603397,0.00057661993,0.00011904083,0.0018863749],"genre_scores_gemma":[0.99266,0.0016674543,0.0016440061,0.00007233782,0.000020326288,0.00011786507,0.0009886286,0.000024859226,0.0028046223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996371,0.000080208796,0.00003921794,0.000047206897,0.00009611453,0.00010010889],"domain_scores_gemma":[0.9997968,0.000041887157,0.00004801818,0.000017334884,0.000012656313,0.00008328135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024532503,0.00048551548,0.00044793586,0.0003318767,0.00014968604,0.00032703573,0.00022288362,0.0003174964,0.0022552353],"category_scores_gemma":[0.00020671773,0.00022096887,0.0003062174,0.0002615656,0.00039666137,0.00013811613,0.0003697854,0.0008911599,0.00056397036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000463221,0.00010619744,0.00018671855,0.00006398924,0.0000049659734,0.00007751254,0.000010459802,0.00004552739,0.9979126,0.000059041635,0.000093833565,0.0009759357],"study_design_scores_gemma":[0.00019106515,0.0012362291,0.006711817,0.000014606344,0.000019391644,0.00047657193,0.000027812024,0.00062202715,0.98789704,0.00005845821,0.002738532,0.000006418832],"about_ca_topic_score_codex":0.0005802161,"about_ca_topic_score_gemma":0.0013380521,"teacher_disagreement_score":0.0022552353,"about_ca_system_score_codex":0.00032936552,"about_ca_system_score_gemma":0.00041743476,"threshold_uncertainty_score":0.0075445175},"labels":[],"label_agreement":null},{"id":"W2014454255","doi":"10.1172/jci22329","title":"The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Institute of Neurosciences, Mental Health and Addiction; Ottawa Public Health","funders":"Canadian Institutes of Health Research","keywords":"ATRX; Corticogenesis; Forebrain; Biology; Neocortex; Clusterin; Chromatin remodeling; Chromatin; Progenitor cell; Neuroscience; Cell biology; Stem cell; Gene; Genetics; Apoptosis; Mutation","score_opus":0.0590363364100671,"score_gpt":0.357584034889507,"score_spread":0.2985476984794399,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014454255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936872,0.0028923815,0.002029674,0.00010727824,0.00001385179,0.0000069299876,0.00016931354,0.00009782608,0.0009955614],"genre_scores_gemma":[0.9969483,0.00090576336,0.0009777275,0.000014175403,0.0000049944715,0.0000061601772,0.00017197206,0.0000080482205,0.0009628409],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999918,0.000012290446,0.000008295838,0.00002075749,0.0000222634,0.000018371346],"domain_scores_gemma":[0.99987745,0.000015333351,0.00004693124,0.00000991146,0.000011012919,0.000039323742],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012078259,0.00016435352,0.00015468193,0.00012898633,0.00014773489,0.00025969523,0.00012454655,0.00013207851,0.0007916462],"category_scores_gemma":[0.0001935434,0.00011586299,0.000087661014,0.00004399921,0.00021832157,0.00012137129,0.00020607478,0.00024943912,0.00034602178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006672838,0.0000042644606,0.00096927787,0.000017919392,0.000002918208,0.00015287058,0.00001072925,0.000037341415,0.9970047,0.00006847784,0.00001911463,0.0016457668],"study_design_scores_gemma":[0.000026213018,0.00020561938,0.08154361,0.00001586395,0.000029645988,0.0031328925,0.00006802849,0.0006901332,0.91034114,0.00020386945,0.0037372597,0.000005615103],"about_ca_topic_score_codex":0.00034528214,"about_ca_topic_score_gemma":0.00048814763,"teacher_disagreement_score":0.0007916462,"about_ca_system_score_codex":0.00014623314,"about_ca_system_score_gemma":0.00016017837,"threshold_uncertainty_score":0.002648294},"labels":[],"label_agreement":null},{"id":"W2014884192","doi":"10.1172/jci45589","title":"Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Liver Center, University of California, San Francisco; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Burroughs Wellcome Fund; University of California, San Francisco; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Gladstone Institutes","keywords":"Chemokine; Fibroblast; Immunology; Immune system; Fibrosis; Inflammation; Cell biology; Acquired immune system; Lung; Integrin; Biology; Dendritic cell; Medicine; Cell; Pathology; Cell culture; Internal medicine","score_opus":0.11496029367965895,"score_gpt":0.40149536486429505,"score_spread":0.2865350711846361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014884192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819234,0.006041365,0.006264777,0.000322033,0.00007513704,0.000067610345,0.0006749071,0.000098448676,0.0045323377],"genre_scores_gemma":[0.9902332,0.0018864777,0.0028235395,0.0000851374,0.000012603935,0.00007218341,0.00063506444,0.000019457606,0.004232273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979764,0.000045009598,0.000023493001,0.000035798163,0.00005564907,0.00004238539],"domain_scores_gemma":[0.99994063,0.000012001247,0.000014871067,0.000013706638,0.0000058194464,0.000012949739],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029632557,0.00024016907,0.0001352315,0.0001985534,0.0001532086,0.0003786166,0.00014389814,0.00031707983,0.0026956992],"category_scores_gemma":[0.00012963898,0.00013252687,0.00021078998,0.00010025789,0.0002152037,0.00018063412,0.00014678063,0.00047587993,0.00064079836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015097803,0.000038432612,0.00025824507,0.000022449229,0.0000032773844,0.00006145557,0.00002479811,0.000041407016,0.99730945,0.00030246287,0.00007819792,0.0017089153],"study_design_scores_gemma":[0.00007392433,0.00043834845,0.004418836,0.000015593698,0.000026692014,0.0010302861,0.000097537144,0.00066141255,0.9824892,0.00020237303,0.010539308,0.0000065244435],"about_ca_topic_score_codex":0.00050662796,"about_ca_topic_score_gemma":0.0008441496,"teacher_disagreement_score":0.0026956992,"about_ca_system_score_codex":0.00017538063,"about_ca_system_score_gemma":0.0001611936,"threshold_uncertainty_score":0.009018064},"labels":[],"label_agreement":null},{"id":"W2015230474","doi":"10.1172/jci11871","title":"A major role for VCAM-1, but not ICAM-1, in early atherosclerosis","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1206,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Toronto General Hospital; University of Toronto","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada; American Heart Association","keywords":"VCAM-1; LDL receptor; Biology; ICAM-1; Cell adhesion molecule; Cholesterol; Null allele; Phenotype; Internal medicine; Endocrinology; Lipoprotein; Immunology; Medicine; Gene; Genetics","score_opus":0.14516416262297396,"score_gpt":0.41801981776737457,"score_spread":0.2728556551444006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015230474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99086994,0.0045560407,0.0024579156,0.00028461288,0.000042424806,0.000017424727,0.00035459394,0.000059909646,0.0013572249],"genre_scores_gemma":[0.991193,0.001966514,0.0027308932,0.00010737011,0.000036980142,0.000049265094,0.00046859877,0.000016156491,0.0034312168],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999821,0.000025475534,0.000017029524,0.000053359792,0.0000389658,0.00004413463],"domain_scores_gemma":[0.99979717,0.00003746744,0.000047592843,0.000025722251,0.000024551648,0.00006752563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020176686,0.00048601467,0.00031742948,0.000534449,0.0003188736,0.00053972396,0.00052554224,0.00064810883,0.0014140462],"category_scores_gemma":[0.00021616099,0.00022877262,0.00020435778,0.00015510996,0.00040286122,0.00037681405,0.00043855113,0.000546564,0.00032369653],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017411476,0.000021673244,0.00081359816,0.00004316055,0.000003617333,0.00010412198,0.000013230102,0.00004544174,0.99683243,0.0002034362,0.000027398171,0.0017178458],"study_design_scores_gemma":[0.00006425211,0.00046410176,0.026427561,0.000029850047,0.00006091616,0.0011581186,0.000069437396,0.0010291443,0.966065,0.00042486424,0.0041887034,0.000018073537],"about_ca_topic_score_codex":0.0005718237,"about_ca_topic_score_gemma":0.00042931671,"teacher_disagreement_score":0.0014140462,"about_ca_system_score_codex":0.00037520676,"about_ca_system_score_gemma":0.00029781787,"threshold_uncertainty_score":0.0047305226},"labels":[],"label_agreement":null},{"id":"W2015847142","doi":"10.1172/jci28334","title":"Myelin oligodendrocyte glycoprotein–specific T and B cells cooperate to induce a Devic-like disease in mice","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":335,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Multiple Sclerosis Society","keywords":"Myelin oligodendrocyte glycoprotein; Multiple sclerosis; Experimental autoimmune encephalomyelitis; Myelin; Pathology; Spinal cord; Immunology; Demyelinating disease; Encephalomyelitis; Genetically modified mouse; Oligodendrocyte; Biology; Medicine; Transgene; Central nervous system; Neuroscience","score_opus":0.10309803955817218,"score_gpt":0.38292683697913515,"score_spread":0.279828797420963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015847142","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9789042,0.0019219256,0.0069523337,0.0005954458,0.00013255564,0.0004585367,0.0014376098,0.0011700599,0.008427328],"genre_scores_gemma":[0.97089934,0.0016216334,0.013935675,0.000597976,0.00016156495,0.00063334306,0.002128483,0.00031046467,0.009711515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841285,0.0003682697,0.00018720736,0.00033364573,0.00035319515,0.00034472166],"domain_scores_gemma":[0.99833006,0.00019655215,0.0005053602,0.0002726838,0.00008801009,0.0006072714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012038397,0.0012722422,0.0007364328,0.0027014473,0.000602431,0.00085441157,0.00090284913,0.0014655167,0.0023614103],"category_scores_gemma":[0.000638904,0.0010090672,0.00078425,0.00051609956,0.00091026287,0.0006395019,0.0010588842,0.001747844,0.0016313322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007128513,0.00057423196,0.0006717188,0.000097471835,0.000032992273,0.00042332266,0.00011874664,0.00022093455,0.99259806,0.0015644182,0.00037690863,0.002608387],"study_design_scores_gemma":[0.0026304002,0.0072802575,0.016102541,0.00019890508,0.0002291039,0.007099139,0.00020335028,0.007857314,0.92476356,0.0018482783,0.031703424,0.00008369837],"about_ca_topic_score_codex":0.0007526657,"about_ca_topic_score_gemma":0.0010772322,"teacher_disagreement_score":0.0027014473,"about_ca_system_score_codex":0.000715809,"about_ca_system_score_gemma":0.0005288578,"threshold_uncertainty_score":0.007899702},"labels":[],"label_agreement":null},{"id":"W2016146452","doi":"10.1172/jci11519","title":"Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-β2 microglobulin–null mice","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; U.S. Public Health Service","keywords":"Haematopoiesis; Biology; Nod; Immunology; CD34; Severe combined immunodeficiency; Myeloid; CD38; Stem cell; Bone marrow; Hematopoietic stem cell; Cancer research; Cell biology; In vivo; Genetics","score_opus":0.10972215998777093,"score_gpt":0.3875863622972163,"score_spread":0.2778642023094454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016146452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943203,0.0010382645,0.0029313723,0.000047564532,0.000009728779,0.000035647503,0.00023574293,0.00008815903,0.0012933394],"genre_scores_gemma":[0.9938069,0.00046832248,0.0023588012,0.000048020698,0.000007081243,0.000052802723,0.000863007,0.000023051882,0.0023719152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983203,0.000023663422,0.000023669132,0.000043383792,0.000045007066,0.000032062533],"domain_scores_gemma":[0.99981064,0.000038866237,0.000040631832,0.000045360517,0.0000134410375,0.000051014355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028313356,0.00031535723,0.00019538478,0.00031911902,0.00009562505,0.0003386098,0.00013905596,0.00020948885,0.001533349],"category_scores_gemma":[0.0001489407,0.0001306672,0.00018859486,0.000112077636,0.00019905478,0.00014752247,0.0002817156,0.00055789016,0.00054436707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000121836434,0.000030264617,0.0012275274,0.000015666868,0.000006040185,0.000063964755,0.00002331531,0.00003653333,0.99633765,0.00009935269,0.000023663464,0.0020141297],"study_design_scores_gemma":[0.000025530837,0.0006714389,0.017116778,0.00001455912,0.000038514216,0.001611176,0.000047256155,0.00068821,0.9763833,0.00009318908,0.0033052058,0.0000048208217],"about_ca_topic_score_codex":0.00017044724,"about_ca_topic_score_gemma":0.00025089094,"teacher_disagreement_score":0.001533349,"about_ca_system_score_codex":0.00010388284,"about_ca_system_score_gemma":0.00013600405,"threshold_uncertainty_score":0.0051295757},"labels":[],"label_agreement":null},{"id":"W2016248729","doi":"10.1172/jci30440","title":"Hypothalamic resistin induces hepatic insulin resistance","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; University of Toronto; National Institutes of Health; American Diabetes Association","keywords":"Resistin; Internal medicine; Endocrinology; Insulin resistance; Proinflammatory cytokine; Hypothalamus; Medicine; Insulin; Hormone; Inflammation; Adipokine","score_opus":0.07178106880786851,"score_gpt":0.37010042133541177,"score_spread":0.29831935252754327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016248729","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954951,0.00093189394,0.0015906475,0.0001720883,0.00006446083,0.00001209242,0.00007216855,0.00009920848,0.0015622854],"genre_scores_gemma":[0.9976815,0.0005707887,0.0005967341,0.000078684854,0.000037521066,0.000014962743,0.00007321592,0.0000237324,0.000922865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999201,0.000015840053,0.0000054922475,0.00001745213,0.00001691278,0.000024202518],"domain_scores_gemma":[0.99990046,0.000018419494,0.00003093343,0.000015347601,0.0000042072325,0.000030623407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008500942,0.00032624477,0.00023921656,0.00016617405,0.00009418442,0.0002891234,0.000084336905,0.00014745932,0.0015640223],"category_scores_gemma":[0.00014184769,0.0001327773,0.00019204193,0.000078590405,0.00037858973,0.00014193456,0.00025421457,0.00072008144,0.00020666352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011618648,0.000047564165,0.00043476318,0.0000464092,0.000014493459,0.00040248825,0.000024588788,0.00007823293,0.99323314,0.0002547737,0.00008492923,0.0042167697],"study_design_scores_gemma":[0.00034088228,0.0027451294,0.020060087,0.000023926232,0.000059528284,0.0023916045,0.000166941,0.0012243387,0.96884537,0.0006028496,0.0035221293,0.000017244958],"about_ca_topic_score_codex":0.00020969448,"about_ca_topic_score_gemma":0.00025937776,"teacher_disagreement_score":0.0015640223,"about_ca_system_score_codex":0.0002497649,"about_ca_system_score_gemma":0.0001243594,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W2016511436","doi":"10.1172/jci9997","title":"A novel vascular smooth muscle chymase is upregulated in hypertensive rats","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Chymase; Vascular smooth muscle; Angiotensin II; Complementary DNA; Renin–angiotensin system; Internal medicine; Endocrinology; Biology; Molecular biology; Enzyme; Biochemistry; Medicine; Smooth muscle; Gene; Blood pressure","score_opus":0.057344061074939064,"score_gpt":0.30505347275542405,"score_spread":0.247709411680485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016511436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99879956,0.00028818485,0.00054249633,0.00003261617,0.000007256285,0.0000064182555,0.0001086045,0.00003092431,0.00018393293],"genre_scores_gemma":[0.9972566,0.0003875754,0.0011929099,0.000030651216,0.0000181393,0.000017665147,0.0003412629,0.000008567467,0.00074655766],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999186,0.000009003952,0.0000065239747,0.000020434674,0.00002258666,0.000022884484],"domain_scores_gemma":[0.9997893,0.000023940811,0.00007344335,0.000016154454,0.000024957853,0.00007225894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008537328,0.00027271695,0.00027952736,0.0002659388,0.00012624625,0.00018469438,0.00007997262,0.00018045455,0.0009462058],"category_scores_gemma":[0.0001460875,0.0001713683,0.00020302703,0.00015744827,0.00018978943,0.000115080984,0.00013235347,0.00036851532,0.0001687718],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001745108,0.000011190146,0.0007669477,0.000018056044,0.0000042389356,0.00014564718,0.000013096787,0.000004109603,0.9983187,0.000014414849,0.000010638072,0.00051844143],"study_design_scores_gemma":[0.000116409945,0.0017107237,0.331642,0.000016286807,0.00011449496,0.002539863,0.0001212103,0.00053476926,0.6616099,0.00015662012,0.0014233069,0.00001439163],"about_ca_topic_score_codex":0.000282647,"about_ca_topic_score_gemma":0.00032394877,"teacher_disagreement_score":0.0009462058,"about_ca_system_score_codex":0.00014586103,"about_ca_system_score_gemma":0.00010559962,"threshold_uncertainty_score":0.0031653047},"labels":[],"label_agreement":null},{"id":"W2016596969","doi":"10.1172/jci44929","title":"MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1L613V mutation","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":234,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Princess Margaret Cancer Centre; Heart and Stroke Foundation; Ontario Institute for Cancer Research; University of Toronto","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Noonan syndrome; Costello syndrome; MAPK/ERK pathway; Mutation; Biology; Germline mutation; Cancer research; Endocrinology; Haploinsufficiency; Internal medicine; Phenotype; Kinase; Medicine; Genetics; Gene","score_opus":0.06381907646871447,"score_gpt":0.2980467769607393,"score_spread":0.2342277004920248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016596969","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944313,0.0009575493,0.0015097185,0.0003358709,0.00013622058,0.00007418944,0.0006285481,0.00024627318,0.0016802669],"genre_scores_gemma":[0.99117625,0.0010676212,0.001996399,0.00016818076,0.000029215069,0.00013954128,0.0006782845,0.000052393643,0.0046921335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996915,0.000054396973,0.000047260815,0.00006332773,0.00006714132,0.0000763841],"domain_scores_gemma":[0.9997296,0.000029615932,0.00006582762,0.000022116334,0.000019820134,0.00013309217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003084886,0.0009005809,0.0004714671,0.00062791986,0.0002834901,0.00035892322,0.00046581592,0.000848291,0.001687603],"category_scores_gemma":[0.00016545372,0.00037369708,0.00043273295,0.0001812516,0.0004804133,0.00038910127,0.00023412712,0.0013837591,0.00048152092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076945854,0.00044107222,0.00019446907,0.00006635358,0.000016953412,0.00016930913,0.000046150035,0.0001739453,0.9959221,0.00027323712,0.00015179277,0.0017752086],"study_design_scores_gemma":[0.000574481,0.0062122513,0.009856338,0.00006548655,0.000121886245,0.0010912942,0.00019762632,0.006096655,0.9694295,0.0004995566,0.0058120955,0.00004288066],"about_ca_topic_score_codex":0.00081912463,"about_ca_topic_score_gemma":0.0016766016,"teacher_disagreement_score":0.001687603,"about_ca_system_score_codex":0.00035052732,"about_ca_system_score_gemma":0.00034980406,"threshold_uncertainty_score":0.0056456327},"labels":[],"label_agreement":null},{"id":"W2017839954","doi":"10.1172/jci66398","title":"An androgen receptor N-terminal domain antagonist for treating prostate cancer","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":311,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; Medical Research and Materiel Command; Canadian Institutes of Health Research; DOD Prostate Cancer Research Program; Prostate Cancer UK","keywords":"Androgen receptor; Prostate cancer; Small molecule; Cancer research; Chemistry; Antagonist; splice; Androgen; Alternative splicing; Cell biology; Cancer; Receptor; Biology; Pharmacology; Computational biology; Hormone; Medicine; Internal medicine; Biochemistry; Gene; Gene isoform","score_opus":0.09595565761914551,"score_gpt":0.45022585827511646,"score_spread":0.3542702006559709,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017839954","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7581912,0.16267096,0.013264508,0.0019879474,0.0006445005,0.0006374397,0.0009825125,0.0005290521,0.06109176],"genre_scores_gemma":[0.93402445,0.040188316,0.008153684,0.00083415094,0.00009675705,0.00011211102,0.00076657615,0.000016828775,0.015807122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999701,0.0000073074807,0.000001678073,0.000004816477,0.000010258515,0.000005842501],"domain_scores_gemma":[0.9999831,0.0000029630037,0.000004216904,0.0000013686822,0.0000020361495,0.0000063461716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081562015,0.00020474005,0.00016335533,0.00011538173,0.00011648523,0.00012531254,0.00016260425,0.00015734487,0.002075814],"category_scores_gemma":[0.000040881205,0.00006496321,0.00011991295,0.00011244009,0.00010372496,0.000101049154,0.00009259588,0.00061717886,0.00062261196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005018719,0.0004913519,0.0005364846,0.0004675325,0.000050539176,0.00029937807,0.0000372249,0.0006322427,0.86305875,0.0019717237,0.0028230203,0.12912998],"study_design_scores_gemma":[0.0012006935,0.013555867,0.014203974,0.00010988743,0.00021634395,0.0062950407,0.000056637797,0.0038499695,0.72054404,0.0006736462,0.23922953,0.00006441007],"about_ca_topic_score_codex":0.00041829073,"about_ca_topic_score_gemma":0.0016034013,"teacher_disagreement_score":0.002075814,"about_ca_system_score_codex":0.00014191223,"about_ca_system_score_gemma":0.00019692442,"threshold_uncertainty_score":0.0069442987},"labels":[],"label_agreement":null},{"id":"W2017869558","doi":"10.1172/jci37196","title":"Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Kidney Foundation of Canada; McGill University","keywords":"Ureter; Biology; Morphogenesis; Craniofacial; Receptor tyrosine kinase; Cell biology; Internal medicine; Endocrinology; Kinase; Medicine; Genetics; Urology","score_opus":0.05172681769371858,"score_gpt":0.34835382691378186,"score_spread":0.2966270092200633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017869558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917532,0.0013903767,0.0038862969,0.00025763543,0.00003181341,0.00004385175,0.0005006848,0.00020309201,0.0019330161],"genre_scores_gemma":[0.9866671,0.0017300094,0.0038488621,0.00013381404,0.000019885907,0.00009145057,0.0004907741,0.00010081537,0.0069173095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995871,0.00009579922,0.000052041592,0.00011451722,0.00007970876,0.00007072575],"domain_scores_gemma":[0.9995759,0.000074021074,0.00016854293,0.000045304307,0.00002555815,0.00011077513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036072085,0.00034051214,0.0003093439,0.00096270087,0.0002632348,0.00047653768,0.00027870323,0.00053953775,0.0022886624],"category_scores_gemma":[0.00038102828,0.0004906062,0.00028435877,0.00015070013,0.00054534554,0.0003633139,0.00037663107,0.0009607332,0.00047273297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049260806,0.000060702816,0.000791022,0.000026708463,0.0000062408735,0.0004533533,0.000054913693,0.00005474459,0.99496585,0.0005128656,0.00006722567,0.002513757],"study_design_scores_gemma":[0.0001490452,0.0012661717,0.016880976,0.000042325188,0.000058297737,0.004235065,0.00013645759,0.0011692519,0.96968937,0.00042231506,0.0059294654,0.00002138645],"about_ca_topic_score_codex":0.0004955102,"about_ca_topic_score_gemma":0.0005914346,"teacher_disagreement_score":0.0022886624,"about_ca_system_score_codex":0.00036573256,"about_ca_system_score_gemma":0.0002642046,"threshold_uncertainty_score":0.007656336},"labels":[],"label_agreement":null},{"id":"W2018101086","doi":"10.1172/jci58457","title":"Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; International Myeloma Foundation; Multiple Myeloma Research Foundation","keywords":"Biology; Lymphokine-activated killer cell; Natural killer cell; Cancer research; Cell; Effector; Gene silencing; Cell biology; Immunology; Interleukin 21; Gene; T cell; In vitro; Immune system; Cytotoxicity; Genetics","score_opus":0.05660253856159979,"score_gpt":0.3237374248741706,"score_spread":0.2671348863125708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018101086","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977055,0.0011571686,0.00035881886,0.000037084046,0.000007721555,0.0000084108,0.000060166258,0.000017326807,0.0006477328],"genre_scores_gemma":[0.9985454,0.00061010453,0.00014390794,0.00001804866,0.0000028708432,0.000006645832,0.000095669646,0.0000024904145,0.0005748818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999324,0.000011713285,0.000004812912,0.000009615588,0.000015551626,0.000026049565],"domain_scores_gemma":[0.99995065,0.000014430017,0.0000135101745,0.0000038907706,0.0000054789284,0.00001203759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000067967,0.0001529625,0.00014084441,0.000118949836,0.000066121975,0.00020298638,0.000050546336,0.00011083649,0.0008677114],"category_scores_gemma":[0.00010254921,0.000055109293,0.0001003036,0.00007471758,0.0001024971,0.00010330515,0.00009516684,0.00027308046,0.00011977365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100536075,0.00002585622,0.00070757186,0.000020787393,0.0000047441467,0.000027515614,0.000008453493,0.00010896407,0.9969457,0.00005006039,0.00002716257,0.0019727536],"study_design_scores_gemma":[0.000029327628,0.0004604611,0.021217061,0.0000047494314,0.00003404093,0.00022076757,0.00004331219,0.0012646997,0.9751008,0.00009512279,0.0015251962,0.000004496208],"about_ca_topic_score_codex":0.00019174148,"about_ca_topic_score_gemma":0.00030800342,"teacher_disagreement_score":0.0008677114,"about_ca_system_score_codex":0.00016663292,"about_ca_system_score_gemma":0.000114386916,"threshold_uncertainty_score":0.0029028058},"labels":[],"label_agreement":null},{"id":"W2018207852","doi":"10.1172/jci17271","title":"Mechano-oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Proinflammatory cytokine; Exocytosis; Mitochondrion; Cell biology; Mitochondrial ROS; Reactive oxygen species; Cytosol; Oxidative stress; Biology; Chemistry; Inflammation; Biochemistry; Secretion; Immunology","score_opus":0.06544586043290376,"score_gpt":0.364294336853772,"score_spread":0.2988484764208682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018207852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99795973,0.0007591518,0.0009048062,0.00007474407,0.000007952145,0.0000102257045,0.000018093378,0.000014839286,0.00025047577],"genre_scores_gemma":[0.99907327,0.00030329186,0.0003930375,0.00001871322,0.0000098132905,0.000010102055,0.000019946921,0.0000018170048,0.00016990674],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988604,0.00003504083,0.000007949855,0.000016970562,0.00002588615,0.000028069475],"domain_scores_gemma":[0.9998876,0.000025957512,0.0000369855,0.000008926069,0.000012731067,0.00002785671],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019309732,0.00016558045,0.00016273936,0.00011422962,0.00009812681,0.00028358147,0.000089817295,0.0002187143,0.0006317138],"category_scores_gemma":[0.00029106656,0.000096881944,0.000107064756,0.00007366443,0.00014706783,0.0002081715,0.00018575102,0.00036769907,0.00007131047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028205235,0.000022475693,0.0006401307,0.000027067847,0.000004869841,0.000164609,0.0000183488,0.000037144328,0.9970312,0.00008723471,0.000021492135,0.0016633387],"study_design_scores_gemma":[0.00009268016,0.0014958618,0.047322303,0.000014400689,0.000025225763,0.0016771633,0.00012419267,0.002078923,0.9457079,0.00032459557,0.0011296668,0.0000070530914],"about_ca_topic_score_codex":0.00010437743,"about_ca_topic_score_gemma":0.00013670459,"teacher_disagreement_score":0.0006317138,"about_ca_system_score_codex":0.00018055938,"about_ca_system_score_gemma":0.000071187016,"threshold_uncertainty_score":0.0021133423},"labels":[],"label_agreement":null},{"id":"W2019054215","doi":"10.1172/jci9594","title":"Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":223,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Aquaporin 2; Intracellular; cGMP-dependent protein kinase; Cell biology; Phosphorylation; Soluble guanylyl cyclase; Protein kinase A; Vasopressin; Apical membrane; Atrial natriuretic peptide; Chemistry; Biology; Nitric oxide; Biochemistry; Endocrinology; Membrane; Mitogen-activated protein kinase kinase","score_opus":0.0299319268108439,"score_gpt":0.30437965450076226,"score_spread":0.2744477276899184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019054215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.985067,0.0051937997,0.003230737,0.0007274616,0.0003166616,0.000087459215,0.00070693524,0.00010198004,0.004568038],"genre_scores_gemma":[0.98938006,0.001928135,0.004007226,0.00044294455,0.000096576434,0.00013493048,0.0006023937,0.000018910487,0.003388904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996648,0.0000684713,0.000034286153,0.000059713424,0.00010683186,0.000065907894],"domain_scores_gemma":[0.9998872,0.00002464888,0.000017848377,0.000017367513,0.000016492544,0.00003640305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030688316,0.00025705373,0.00039398516,0.00019071331,0.00018327289,0.00024703683,0.00027959267,0.0004061708,0.0011823818],"category_scores_gemma":[0.0002356747,0.00019647504,0.0004958036,0.00018420914,0.00026441048,0.00037183517,0.00033329497,0.00067125,0.00037178767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021343828,0.00005844986,0.000076869364,0.00006708561,0.000004640385,0.00010167128,0.000025871355,0.000050172253,0.99847716,0.00015259712,0.00007703353,0.0006950174],"study_design_scores_gemma":[0.00022577164,0.0010168643,0.012307461,0.000018228484,0.000029827035,0.00057881325,0.00009981735,0.0031827416,0.9730102,0.00036912368,0.009140954,0.00002024413],"about_ca_topic_score_codex":0.0009847052,"about_ca_topic_score_gemma":0.0013531606,"teacher_disagreement_score":0.0011823818,"about_ca_system_score_codex":0.00034441176,"about_ca_system_score_gemma":0.00032633715,"threshold_uncertainty_score":0.003955424},"labels":[],"label_agreement":null},{"id":"W2019161989","doi":"10.1172/jci68035","title":"Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi–like features","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Société Francophone du Diabète","keywords":"Haploinsufficiency; Obesity; Loss function; Internal medicine; Endocrinology; Biology; Gene; Genetics; Medicine; Phenotype","score_opus":0.03152585440061885,"score_gpt":0.32689034302281816,"score_spread":0.29536448862219933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019161989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99874276,0.00017604232,0.00068628596,0.000020004973,0.0000038677094,0.000007354717,0.00013226521,0.000025135972,0.00020631134],"genre_scores_gemma":[0.99797195,0.00019445759,0.0011998726,0.000019523457,0.0000069060366,0.000009617177,0.00020973528,0.00001623192,0.00037171022],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998461,0.000029468447,0.000018525405,0.00004313353,0.000040894985,0.00002188049],"domain_scores_gemma":[0.9997422,0.00006261502,0.0001240268,0.000016343047,0.000008629363,0.00004617836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014630916,0.0007557274,0.00021688663,0.000734387,0.0001885093,0.0001409984,0.00022123363,0.0003084945,0.0014878871],"category_scores_gemma":[0.00040622984,0.0002444807,0.0003546366,0.00029993386,0.0003758818,0.000080416,0.00038601135,0.00042931913,0.00023279554],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008649317,0.00008497216,0.090388425,0.000095551535,0.0001717528,0.008928758,0.00021117234,0.0006220587,0.88973856,0.00030655778,0.00020653603,0.008380744],"study_design_scores_gemma":[0.0001305241,0.000706483,0.661654,0.00004385159,0.00027843946,0.04882663,0.00021918396,0.0039287033,0.27993354,0.00035448626,0.0038733566,0.000050778533],"about_ca_topic_score_codex":0.0005431416,"about_ca_topic_score_gemma":0.0009872683,"teacher_disagreement_score":0.0014878871,"about_ca_system_score_codex":0.00015052837,"about_ca_system_score_gemma":0.00012814852,"threshold_uncertainty_score":0.0049774647},"labels":[],"label_agreement":null},{"id":"W2019298465","doi":"10.1172/jci60981","title":"Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; National Institutes of Health; College of Medicine, Seoul National University; National Institute on Deafness and Other Communication Disorders; National Eye Institute; Wellcome Trust; Seoul National University Bundang Hospital; Seoul National University","keywords":"Ciliopathies; Cilium; Ciliopathy; Ciliogenesis; Biology; Cell biology; Joubert syndrome; Intraflagellar transport; Bardet–Biedl syndrome; Genetics; Basal body; Mutant; Phenotype; Flagellum; Gene","score_opus":0.04957735038830351,"score_gpt":0.33425959680998174,"score_spread":0.2846822464216782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019298465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903312,0.00092467543,0.004650445,0.00018521397,0.000109339206,0.00005947017,0.0013003225,0.0006682997,0.0017711212],"genre_scores_gemma":[0.9887799,0.0008612138,0.0032672393,0.00009027479,0.000024736164,0.00006618668,0.0010979653,0.00017771627,0.0056347596],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999652,0.00002315118,0.00006460309,0.00008556993,0.00011172381,0.000062833205],"domain_scores_gemma":[0.99955505,0.000033613214,0.00014041993,0.000039658204,0.00002602042,0.00020526753],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001625689,0.0009504144,0.00038760024,0.0006528588,0.00025539185,0.00034991748,0.0006694465,0.0007894728,0.001997532],"category_scores_gemma":[0.00019855017,0.00044259426,0.00045436746,0.00018537592,0.00057293824,0.00029469543,0.00050784706,0.0010676221,0.0009865697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105609295,0.000024743551,0.00009005209,0.000025437594,0.000007734388,0.00013887085,0.000009505244,0.00008230705,0.9987024,0.00009792838,0.0000421988,0.0006731738],"study_design_scores_gemma":[0.00008607081,0.00042001504,0.0049062395,0.000015830145,0.00005247958,0.0009839223,0.000041955685,0.0020687385,0.9879331,0.00012295773,0.0033506167,0.000018014945],"about_ca_topic_score_codex":0.001226045,"about_ca_topic_score_gemma":0.001700422,"teacher_disagreement_score":0.001997532,"about_ca_system_score_codex":0.0004553148,"about_ca_system_score_gemma":0.00043153932,"threshold_uncertainty_score":0.006682396},"labels":[],"label_agreement":null},{"id":"W2019420982","doi":"10.1172/jci12159","title":"Modulation of T-cell responses to alloantigens by TR6/DcR3","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"National Cancer Institute; Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Roche Organ Transplant Research Foundation; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"Lymphokine; Cytotoxic T cell; Immune system; Biology; Immunology; Receptor; Cell biology; In vitro; Genetics","score_opus":0.054453761477642366,"score_gpt":0.36840423337718736,"score_spread":0.313950471899545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019420982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930514,0.0020445988,0.0015164984,0.00013783063,0.000048655962,0.00003914093,0.00020462979,0.00010221849,0.002854957],"genre_scores_gemma":[0.9951557,0.0009091007,0.0014309514,0.000099979865,0.000029407653,0.000022762775,0.00036012148,0.000029479985,0.001962483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997788,0.000053125492,0.000016990376,0.000028764804,0.000043113763,0.00007912913],"domain_scores_gemma":[0.99987674,0.00001401479,0.000028213895,0.0000127927315,0.000017160903,0.00005097965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018677508,0.00029361516,0.00019667222,0.00016148573,0.00011326127,0.00028352902,0.00021582756,0.00023876858,0.00175684],"category_scores_gemma":[0.00016658637,0.00007229045,0.00019191763,0.00010517663,0.00014233736,0.0001106289,0.00015227459,0.00070636655,0.0009608818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021097694,0.00004778993,0.000114737246,0.00002270408,0.000002651015,0.00004227945,0.000006292399,0.00004058448,0.9977877,0.000044922024,0.000035468463,0.0016438464],"study_design_scores_gemma":[0.00013597349,0.0011271969,0.0034993172,0.000010368311,0.00002443412,0.0005296854,0.00003643101,0.0012683966,0.9896237,0.0000735003,0.0036649473,0.0000059997687],"about_ca_topic_score_codex":0.0002710538,"about_ca_topic_score_gemma":0.00041475473,"teacher_disagreement_score":0.00175684,"about_ca_system_score_codex":0.00020028617,"about_ca_system_score_gemma":0.00012951445,"threshold_uncertainty_score":0.0058772564},"labels":[],"label_agreement":null},{"id":"W2019449233","doi":"10.1172/jci33136","title":"Low-molecular-weight S-nitrosothiols and blood vessel injury","year":2007,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; University of Toronto; King's College London; Heart and Stroke Foundation of Canada","keywords":"Acetylcysteine; Medicine; Hypoxia (environmental); Blood vessel; In vivo; Pathology; Antioxidant; Biology; Internal medicine; Chemistry; Biochemistry; Oxygen","score_opus":0.04107968079647417,"score_gpt":0.36289904367634146,"score_spread":0.3218193628798673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019449233","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022674767,0.01469786,0.00085841486,0.92410904,0.019942742,0.00007255205,0.00008291593,0.00014429455,0.017417317],"genre_scores_gemma":[0.21375354,0.028966496,0.0024295137,0.5670742,0.1464755,0.00020136836,0.000096697695,0.000066423614,0.04093631],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995012,0.00019005638,0.00005463563,0.00006329545,0.0001312294,0.0000595332],"domain_scores_gemma":[0.99859923,0.00092933537,0.0001517408,0.00006913558,0.00014042297,0.00011004764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061715447,0.0006249058,0.0008182232,0.0003374992,0.0010121568,0.0010430217,0.0007549454,0.014894822,0.0045241453],"category_scores_gemma":[0.0043754433,0.00029403873,0.00043403573,0.0003297023,0.0014962137,0.001209744,0.00033719014,0.0072348868,0.0027428481],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013489659,0.0005857196,0.008710891,0.00060368713,0.00008999651,0.15952562,0.00058345194,0.00044977793,0.0081068855,0.011042468,0.7122327,0.096719794],"study_design_scores_gemma":[0.00081252377,0.0012641948,0.016348371,0.00056926487,0.00011634174,0.20969951,0.0007904323,0.0026952878,0.006268929,0.027515631,0.73382556,0.00009395353],"about_ca_topic_score_codex":0.00050228165,"about_ca_topic_score_gemma":0.000913481,"teacher_disagreement_score":0.014894822,"about_ca_system_score_codex":0.0013906884,"about_ca_system_score_gemma":0.00045677743,"threshold_uncertainty_score":0.015134752},"labels":[],"label_agreement":null},{"id":"W2019535767","doi":"10.1172/jci63681","title":"IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":253,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research; University of Toronto","funders":"Gemeinnützige Hertie-Stiftung; Deutsche Forschungsgemeinschaft; Philipps-Universität Marburg","keywords":"Adoptive cell transfer; Experimental autoimmune encephalomyelitis; CD8; Immunology; Interleukin 17; Cytotoxic T cell; Autoimmunity; Interleukin 21; Biology; Interleukin 3; T cell; Multiple sclerosis; Immune system; In vitro","score_opus":0.031501001752118174,"score_gpt":0.29671541927859935,"score_spread":0.26521441752648117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019535767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931131,0.0023269404,0.0009384629,0.0002888593,0.00008435596,0.000038573566,0.00023273888,0.0001441567,0.0028326763],"genre_scores_gemma":[0.99632794,0.0010927966,0.0010266153,0.000112910566,0.0001074445,0.00005320715,0.000320515,0.000028138247,0.0009304495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99967504,0.00011254996,0.00004089883,0.000030350213,0.00005560474,0.00008554057],"domain_scores_gemma":[0.99963284,0.00007034361,0.000060777485,0.000063696076,0.000043387023,0.0001289835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036088788,0.0004878562,0.00041810996,0.000530253,0.00020299954,0.00057908683,0.00020069374,0.0003244513,0.0016422123],"category_scores_gemma":[0.0003932403,0.00020921855,0.0002525963,0.00016243146,0.00037709056,0.00025502904,0.000320323,0.001144337,0.0011911086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010518573,0.00032381754,0.0028283328,0.00017901347,0.000014777586,0.00036028944,0.00005730144,0.00020213047,0.98436546,0.00014004455,0.00039739916,0.010079606],"study_design_scores_gemma":[0.0008460837,0.003944846,0.023206025,0.00016122201,0.00013736666,0.0022186374,0.00028357585,0.003663995,0.94700027,0.00092936086,0.017586203,0.000022340071],"about_ca_topic_score_codex":0.00022340742,"about_ca_topic_score_gemma":0.0003620659,"teacher_disagreement_score":0.0016422123,"about_ca_system_score_codex":0.00019582755,"about_ca_system_score_gemma":0.00032213295,"threshold_uncertainty_score":0.0054937005},"labels":[],"label_agreement":null},{"id":"W2020396176","doi":"10.1172/jci32490","title":"Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":303,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Heart, Lung, and Blood Institute","keywords":"Cardiology; Apoptosis; Ventricular remodeling; Myocardial infarction; Internal medicine; Ligation; Medicine; Ischemia; Biology","score_opus":0.0520219633076366,"score_gpt":0.359306710361466,"score_spread":0.3072847470538294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020396176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942977,0.0008723776,0.0035174408,0.00015340088,0.000027536937,0.000043376578,0.00025660283,0.00015203925,0.0006795289],"genre_scores_gemma":[0.9912816,0.0011275546,0.0043387855,0.00011454803,0.000022026807,0.00012606269,0.00050937163,0.00006557909,0.002414442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998041,0.000033062664,0.000026031794,0.00003853815,0.00003837722,0.000059966125],"domain_scores_gemma":[0.9998149,0.000019099401,0.00006837314,0.000021001411,0.000013958664,0.000062680396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027594104,0.0006247593,0.00039757942,0.00044186728,0.00023952808,0.0003276274,0.00032378294,0.00037978604,0.0009650476],"category_scores_gemma":[0.00016373348,0.00028752736,0.0002977239,0.0001466638,0.00046127092,0.0003072283,0.00020374941,0.0010743662,0.0003557956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027772126,0.000098769626,0.00021477076,0.000028583905,0.000005843572,0.00004963248,0.0000140930115,0.000064089574,0.9977564,0.00009500593,0.000034679008,0.0013603892],"study_design_scores_gemma":[0.00020542849,0.0019339368,0.007858575,0.000023498049,0.00004735731,0.0005989557,0.000049831833,0.0016235125,0.9859708,0.00019345316,0.0014856169,0.000009033889],"about_ca_topic_score_codex":0.00034612045,"about_ca_topic_score_gemma":0.00074104074,"teacher_disagreement_score":0.0009650476,"about_ca_system_score_codex":0.00029312706,"about_ca_system_score_gemma":0.00022815248,"threshold_uncertainty_score":0.003228426},"labels":[],"label_agreement":null},{"id":"W2020460921","doi":"10.1172/jci36882","title":"Identification of a bone marrow–derived epithelial-like population capable of repopulating injured mouse airway epithelium","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto","keywords":"Bone marrow; Biology; Respiratory epithelium; Stromal cell; Progenitor cell; Population; Epithelium; Stem cell; Immunology; Cell biology; Pathology; Lung; Context (archaeology); Regeneration (biology); Cell type; Cell; Cancer research; Medicine; Internal medicine","score_opus":0.09867813191151116,"score_gpt":0.4318552241288503,"score_spread":0.33317709221733915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020460921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98148835,0.0017469666,0.014770567,0.00011978812,0.000014612384,0.00009834952,0.0003201227,0.00010646153,0.0013348983],"genre_scores_gemma":[0.98015195,0.0012397435,0.014471641,0.00008978866,0.00001755456,0.00013209802,0.00087460753,0.000035896235,0.0029866255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998591,0.000023854029,0.000012722064,0.000028964216,0.00004795463,0.000027405305],"domain_scores_gemma":[0.99991477,0.000014123995,0.000015411448,0.00001417607,0.000014497583,0.000027036922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002547124,0.0002014691,0.000214162,0.000510327,0.00015465346,0.00029980778,0.00015459965,0.00023477561,0.0009899673],"category_scores_gemma":[0.00010852238,0.000113141235,0.0001554763,0.00011704718,0.00014887397,0.00014580527,0.00019735844,0.0004490934,0.00044814852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039783976,0.0000142697545,0.00029588788,0.000011765381,0.0000015340436,0.000033927256,0.000015076004,0.000014943354,0.99775225,0.00008664025,0.000011572696,0.001722376],"study_design_scores_gemma":[0.000022559321,0.0003302188,0.007739685,0.000014203556,0.00002632657,0.0005611118,0.000058725465,0.0011187225,0.98731494,0.000094779956,0.0027146782,0.0000039569304],"about_ca_topic_score_codex":0.00022558082,"about_ca_topic_score_gemma":0.0003807024,"teacher_disagreement_score":0.0009899673,"about_ca_system_score_codex":0.000100991354,"about_ca_system_score_gemma":0.00013931822,"threshold_uncertainty_score":0.0033118129},"labels":[],"label_agreement":null},{"id":"W2020764743","doi":"10.1172/jci44778","title":"A noninhibitory mutant of the caveolin-1 scaffolding domain enhances eNOS-derived NO synthesis and vasodilation in mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital","funders":"National Heart, Lung, and Blood Institute; British Columbia Knowledge Development Fund; Canadian Institutes of Health Research; Raymond and Beverly Sackler Institute for Biological, Physical and Engineering Sciences, Yale University; Yale University; National Institutes of Health; Michael Smith Health Research BC","keywords":"Enos; Mutant; Caveolin 1; Vasodilation; Internal medicine; Scaffold protein; Endocrinology; Medicine; Biology; Chemistry; Cell biology; Nitric oxide; Biochemistry; Nitric oxide synthase; Signal transduction; Gene","score_opus":0.03593085963421172,"score_gpt":0.28586938726464545,"score_spread":0.24993852763043373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020764743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917154,0.0007881603,0.0038088963,0.0004130543,0.00010422008,0.0000918391,0.0007178951,0.00040384624,0.0019566012],"genre_scores_gemma":[0.9868253,0.00084062596,0.004894851,0.00024802203,0.00005855171,0.00016476325,0.0008728661,0.00019259211,0.0059024417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995369,0.000080427235,0.00005751242,0.00014102651,0.00008098324,0.00010312142],"domain_scores_gemma":[0.99945694,0.00010004581,0.00017649193,0.00004443911,0.00002044935,0.00020160123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004293425,0.00085135666,0.00055595505,0.0008447639,0.00031604676,0.00047129524,0.0006411566,0.0010451304,0.002376762],"category_scores_gemma":[0.00024956994,0.0005286595,0.0005369403,0.00025296528,0.0010570982,0.00046036908,0.00038898241,0.0016507737,0.0005552841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006958164,0.00030660056,0.00014788912,0.000049373415,0.000013411381,0.00014469765,0.000029781106,0.000092734124,0.997071,0.00040432965,0.00010226244,0.00094205886],"study_design_scores_gemma":[0.00063666835,0.002855959,0.0067487983,0.000045340104,0.00012455403,0.0014119858,0.00006380298,0.0035234718,0.9788021,0.00039129157,0.005363346,0.000032837008],"about_ca_topic_score_codex":0.00064488547,"about_ca_topic_score_gemma":0.00092913926,"teacher_disagreement_score":0.002376762,"about_ca_system_score_codex":0.0005728419,"about_ca_system_score_gemma":0.00036592022,"threshold_uncertainty_score":0.007951081},"labels":[],"label_agreement":null},{"id":"W2020831499","doi":"10.1172/jci15420","title":"Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":418,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Caprion (Canada)","funders":"National Institute of General Medical Sciences; U.S. Public Health Service; American Heart Association","keywords":"Lactosylceramide; Caveolae; Golgi apparatus; Sphingolipid; Cell biology; Rab; Lipid raft; Ceramide; Vesicular transport protein; Sphingomyelin; Biology; Clathrin; Glycosphingolipid; Lipid microdomain; Endocytosis; Chemistry; Biochemistry; Vesicle; Signal transduction; Receptor; Glycolipid; Cholesterol; GTPase; Membrane; Endoplasmic reticulum","score_opus":0.03484175087733286,"score_gpt":0.2877694204625575,"score_spread":0.2529276695852246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020831499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923847,0.0021829482,0.002873772,0.00016139004,0.000021687074,0.00003976261,0.00015593054,0.00012154184,0.0020583],"genre_scores_gemma":[0.9921266,0.0017410775,0.003345533,0.0000397187,0.0000068932004,0.000027523989,0.00023350921,0.000020493415,0.0024586965],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998888,0.000021739841,0.000011643701,0.000010688897,0.00003788011,0.000029207959],"domain_scores_gemma":[0.99994063,0.0000076500655,0.000010493602,0.000010208392,0.000014895396,0.000016091453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020762203,0.00035966048,0.00016961587,0.00023813655,0.0002498709,0.00034713955,0.0001880838,0.0003262631,0.0005504096],"category_scores_gemma":[0.00021446607,0.000116030606,0.00015301866,0.00010826574,0.00021887492,0.00019023965,0.00020432896,0.00029958008,0.0003826766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008786101,0.000015792455,0.0002196763,0.000035139794,0.000004213967,0.00025477746,0.000013067545,0.00013693958,0.99653625,0.0004824426,0.00007024397,0.0021436322],"study_design_scores_gemma":[0.000036615238,0.00009114258,0.0025133258,0.0000065296977,0.000015617004,0.0010275454,0.000032008706,0.001581354,0.9907108,0.00018302053,0.003796319,0.000005825534],"about_ca_topic_score_codex":0.0021099509,"about_ca_topic_score_gemma":0.002245829,"teacher_disagreement_score":0.0021099509,"about_ca_system_score_codex":0.0006368421,"about_ca_system_score_gemma":0.0004151064,"threshold_uncertainty_score":0.0046206713},"labels":[],"label_agreement":null},{"id":"W2021127134","doi":"10.1172/jci38289","title":"A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Liver regeneration; Reperfusion injury; Hepatoprotection; Liver injury; Regeneration (biology); Steatosis; C5a receptor; Context (archaeology); Liver transplantation; Complement system; Ischemia; Endocrinology; Internal medicine; Pharmacology; Biology; Immunology; Transplantation; Medicine; Cell biology; Antibody; Biochemistry","score_opus":0.06360184311612735,"score_gpt":0.3857314280302442,"score_spread":0.3221295849141168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021127134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9690608,0.0057320786,0.013872241,0.0009641883,0.00017679785,0.0008415856,0.0023275495,0.00092907326,0.006095859],"genre_scores_gemma":[0.9576313,0.0031934741,0.022665711,0.000723263,0.00008445392,0.0019950962,0.0021804066,0.00020115035,0.01132512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990293,0.00016655924,0.00013153195,0.00024509558,0.00018838713,0.00023916738],"domain_scores_gemma":[0.99952614,0.00003740088,0.00015974086,0.00007097467,0.000038313243,0.00016733228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009199129,0.001401274,0.0007121578,0.002138321,0.0007198838,0.00083160785,0.0010224433,0.0015157849,0.0026340743],"category_scores_gemma":[0.00023025411,0.0009502228,0.0007985762,0.000616437,0.0012037565,0.0010226483,0.0007697546,0.0023129047,0.0010337268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002166167,0.0007071235,0.0003078861,0.00015179688,0.000022965289,0.0001242296,0.00009378827,0.00018236153,0.991165,0.0012726274,0.00019514335,0.0036109376],"study_design_scores_gemma":[0.00088229025,0.00695897,0.0052606463,0.00010185705,0.00010136332,0.0009760319,0.00010293963,0.0026825932,0.97352433,0.00081645447,0.008547892,0.000044707795],"about_ca_topic_score_codex":0.0009806738,"about_ca_topic_score_gemma":0.001827328,"teacher_disagreement_score":0.0026340743,"about_ca_system_score_codex":0.0010427594,"about_ca_system_score_gemma":0.0009206916,"threshold_uncertainty_score":0.008811891},"labels":[],"label_agreement":null},{"id":"W2022497396","doi":"10.1172/jci10536","title":"Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"DOD Prostate Cancer Research Program; National Cancer Institute; National Institutes of Health; Hospital for Sick Children; U.S. Department of Defense","keywords":"Focal adhesion; Cell migration; LYN; Cell biology; Tyrosine phosphorylation; DU145; Phosphorylation; Neprilysin; Cell growth; Signal transduction; Chemistry; Biology; Proto-oncogene tyrosine-protein kinase Src; Cell; LNCaP; Cancer cell; Biochemistry","score_opus":0.043823755521184976,"score_gpt":0.3497352575076599,"score_spread":0.3059115019864749,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022497396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904165,0.0045157424,0.0014843168,0.00020308867,0.00006248932,0.000063054315,0.0002877814,0.00012328588,0.0028438172],"genre_scores_gemma":[0.99130124,0.003037944,0.0015527379,0.00007114232,0.00001445869,0.00007555343,0.00056908233,0.000012006433,0.0033658461],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998765,0.00002085093,0.000010584871,0.000015266012,0.0000318922,0.00004477997],"domain_scores_gemma":[0.9999647,0.000007544814,0.000006958235,0.000004503058,0.0000041941503,0.000012174721],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104418155,0.00040662233,0.00027919575,0.00018720225,0.00014384052,0.0002084438,0.00022617588,0.00024566232,0.0010993697],"category_scores_gemma":[0.00009246459,0.00012648012,0.0002878889,0.00014413035,0.00014069863,0.0000990876,0.00013904972,0.000655201,0.00028974342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017930262,0.00017764617,0.000118070144,0.000082349325,0.000011292228,0.00004149382,0.000009464379,0.00009951599,0.99542785,0.00009090584,0.00014564623,0.0036165072],"study_design_scores_gemma":[0.00011432407,0.001588757,0.005913457,0.000010419272,0.0000314203,0.0003145041,0.000017587545,0.0018246823,0.9854414,0.00004779469,0.0046894,0.000006385704],"about_ca_topic_score_codex":0.0010439095,"about_ca_topic_score_gemma":0.0020652167,"teacher_disagreement_score":0.0010993697,"about_ca_system_score_codex":0.000313921,"about_ca_system_score_gemma":0.0003673282,"threshold_uncertainty_score":0.0036777854},"labels":[],"label_agreement":null},{"id":"W2024126525","doi":"10.1172/jci23741","title":"Human cardiac potassium channel DNA polymorphism modulates access to drug-binding site and causes drug resistance","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; School of Medicine, Vanderbilt University; Vanderbilt University; U.S. Public Health Service; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Potassium channel; Potassium channel blocker; Circular dichroism; Quinidine; Drug; HEK 293 cells; Biophysics; Helix (gastropod); Chemistry; Wild type; Biology; Molecular biology; Stereochemistry; Biochemistry; Pharmacology; Gene; Mutant","score_opus":0.046319084545337674,"score_gpt":0.36083307761531064,"score_spread":0.31451399306997296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024126525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99860424,0.0001769252,0.0007593437,0.000026336711,0.0000065977733,0.0000066629077,0.00009756584,0.000015501138,0.00030686974],"genre_scores_gemma":[0.99952304,0.00005081917,0.00019904842,0.000019370187,0.0000028232103,0.0000022716913,0.00007952167,0.0000048027264,0.000118268814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989974,0.00002133075,0.000012641523,0.00003415009,0.000018508723,0.000013603476],"domain_scores_gemma":[0.9999057,0.000024563917,0.000036705977,0.000007798609,0.000007432981,0.00001777397],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008003876,0.00013611549,0.00013638104,0.00013816539,0.00007639507,0.00012664522,0.00008431752,0.00022470993,0.0013909686],"category_scores_gemma":[0.00025199013,0.000054229968,0.00013408628,0.00010003233,0.0001662067,0.000096089585,0.000094156756,0.00022391707,0.00029559137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020538579,0.000020020972,0.00869266,0.000021665799,0.000017182248,0.00034826808,0.000032690026,0.00010836352,0.98775905,0.00009664974,0.000046167595,0.0026518737],"study_design_scores_gemma":[0.000084925996,0.0009939917,0.29514807,0.000030167672,0.00013789162,0.009443831,0.0001527023,0.005142519,0.684428,0.00034360637,0.004057093,0.000037274847],"about_ca_topic_score_codex":0.00027185844,"about_ca_topic_score_gemma":0.00031509608,"teacher_disagreement_score":0.0013909686,"about_ca_system_score_codex":0.000121453144,"about_ca_system_score_gemma":0.00005833136,"threshold_uncertainty_score":0.0046532154},"labels":[],"label_agreement":null},{"id":"W2024443346","doi":"10.1172/jci32638","title":"Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; National Institutes of Health; Muscular Dystrophy Association","keywords":"Myotonia; Skeletal muscle; Internal medicine; Endocrinology; Muscle weakness; Myotonia congenita; Weakness; Periodic paralysis; Extensor digitorum longus muscle; Sodium channel; Ouabain; Biology; Chemistry; Medicine; Anatomy; Paralysis; Sodium; Myotonic dystrophy; Surgery","score_opus":0.04021668770725671,"score_gpt":0.30393776181247306,"score_spread":0.26372107410521634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024443346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945268,0.00061280676,0.0031537416,0.00011186339,0.00003976189,0.000072860144,0.0004942408,0.00015424403,0.0008337133],"genre_scores_gemma":[0.9928712,0.00049533596,0.0032041362,0.000070752954,0.00001455779,0.00009412478,0.0008839275,0.000043795135,0.002322232],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996861,0.000059149952,0.000064082735,0.0000763756,0.000072661096,0.000041565825],"domain_scores_gemma":[0.9998068,0.00003573372,0.00007508787,0.000020560481,0.000010445334,0.000051364328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028017195,0.0004725845,0.00029665063,0.0003702387,0.00014847517,0.00024886805,0.00027924316,0.00066984026,0.0015802288],"category_scores_gemma":[0.00022138325,0.00026672572,0.0003071756,0.00019024454,0.00038259925,0.0002043615,0.0003183839,0.00049733126,0.00052570784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000113478345,0.00003134136,0.00017392109,0.000028886809,0.00001013019,0.0002038549,0.00001024072,0.00006206417,0.99859256,0.00010247272,0.00003206667,0.0006391119],"study_design_scores_gemma":[0.00021257615,0.0011072621,0.008040495,0.000030819454,0.00006111471,0.004227973,0.000037369507,0.0016831191,0.98028886,0.00017349067,0.0041231,0.000013819717],"about_ca_topic_score_codex":0.00025896757,"about_ca_topic_score_gemma":0.0004291056,"teacher_disagreement_score":0.0015802288,"about_ca_system_score_codex":0.00035406588,"about_ca_system_score_gemma":0.00017877533,"threshold_uncertainty_score":0.0052863955},"labels":[],"label_agreement":null},{"id":"W2024505986","doi":"10.1172/jci45096","title":"α3(V) Collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Homeostasis; Glucose homeostasis; Peripheral; Pancreatic islets; Chemistry; Internal medicine; Endocrinology; Islet; Cell biology; Biology; Insulin; Medicine; Insulin resistance","score_opus":0.08197850286971431,"score_gpt":0.3801351713258755,"score_spread":0.2981566684561612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024505986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97642857,0.0028439164,0.008500246,0.0007590922,0.00017202282,0.00019520048,0.0034992448,0.0005275089,0.007074185],"genre_scores_gemma":[0.97370625,0.0021599636,0.009617318,0.00040601686,0.00006610175,0.00029228054,0.0025089195,0.0003127631,0.010930469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951696,0.000092865026,0.00006722275,0.00011087218,0.00012062511,0.00009147211],"domain_scores_gemma":[0.9993974,0.000049713966,0.00026550438,0.000037918584,0.000028077304,0.00022130387],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033783575,0.00084649434,0.00027613918,0.00069593976,0.00040801242,0.00068385224,0.00041311618,0.000896941,0.0041879076],"category_scores_gemma":[0.00020685159,0.0004917666,0.00046755062,0.00036778202,0.0006163779,0.0003381928,0.00037517186,0.0016378709,0.0011634151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048260402,0.000075242984,0.00044628128,0.000045639485,0.000008094136,0.00022315072,0.000021756205,0.000041480707,0.99690384,0.00019612936,0.00015784464,0.0013978953],"study_design_scores_gemma":[0.00039609728,0.0014692757,0.035953857,0.0001098905,0.00011117557,0.0053926283,0.0002238794,0.0015893045,0.93724823,0.00045354155,0.017021295,0.00003084185],"about_ca_topic_score_codex":0.0009275891,"about_ca_topic_score_gemma":0.0014075019,"teacher_disagreement_score":0.0041879076,"about_ca_system_score_codex":0.00051495736,"about_ca_system_score_gemma":0.0004892759,"threshold_uncertainty_score":0.014009953},"labels":[],"label_agreement":null},{"id":"W2024580708","doi":"10.1172/jci71863","title":"Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Chemistry; National Institute of General Medical Sciences; National Institutes of Health; Faculty of Medicine, Chiang Mai University; National Heart, Lung, and Blood Institute; Commission on Higher Education; Chiang Mai University; University of Alberta; University of Louisville; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; Thailand Research Fund; University of Cincinnati; American Heart Association","keywords":"Lipotoxicity; Sodium–hydrogen antiporter; Reabsorption; Chemistry; Apoptosis; Tubule; Cell biology; Kidney; Internal medicine; Endocrinology; Endocytosis; Pi; Biology; Biochemistry; Receptor; Sodium; Diabetes mellitus; Medicine","score_opus":0.051761564393303185,"score_gpt":0.37047479515482157,"score_spread":0.31871323076151836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024580708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886058,0.0022029215,0.007124606,0.0002055201,0.00005193528,0.00004684343,0.00029653404,0.0001557808,0.0013099301],"genre_scores_gemma":[0.9946996,0.00072934123,0.0015931211,0.00008028425,0.000011644835,0.00004689781,0.0002441223,0.000018008164,0.0025770403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99970275,0.000038970855,0.00002470019,0.00007123134,0.000079000965,0.00008334184],"domain_scores_gemma":[0.99985516,0.000019048364,0.000031192176,0.000020849451,0.000021952757,0.00005173835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028400734,0.0003666958,0.00049432303,0.00027157867,0.00020071439,0.00045115687,0.00023307274,0.00039933508,0.0018832235],"category_scores_gemma":[0.00012697303,0.00019825318,0.0004252795,0.00020639769,0.00028809073,0.00042938197,0.00028347442,0.000961928,0.00036219365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003166429,0.000039743172,0.00023847679,0.000037242655,0.000011969618,0.000034416804,0.00001333448,0.000048481666,0.99835676,0.00008951216,0.000030060379,0.00078323274],"study_design_scores_gemma":[0.000032551106,0.0005620289,0.006578032,0.0000064499304,0.000028292357,0.00015452296,0.000041818537,0.0013784828,0.9899474,0.000102383485,0.001163593,0.0000044468734],"about_ca_topic_score_codex":0.00064254063,"about_ca_topic_score_gemma":0.00085896574,"teacher_disagreement_score":0.0018832235,"about_ca_system_score_codex":0.0004985418,"about_ca_system_score_gemma":0.00034301946,"threshold_uncertainty_score":0.0062999725},"labels":[],"label_agreement":null},{"id":"W2025239337","doi":"10.1172/jci45843","title":"3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"Canadian Cancer Society Research Institute; University of California, San Diego; Terry Fox Research Institute; University of Toronto","keywords":"Osteoclast; Osteoblast; Bone resorption; Cell biology; Bone remodeling; Osteoporosis; Bone cell; Homeostasis; Chemistry; Internal medicine; Endocrinology; Cancer research; Biology; In vitro; Medicine; Biochemistry","score_opus":0.1162108818171565,"score_gpt":0.3461783920652619,"score_spread":0.2299675102481054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025239337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9808441,0.0032278826,0.008128186,0.0004916631,0.00012528182,0.00011937045,0.0028403376,0.0007836218,0.0034395973],"genre_scores_gemma":[0.973218,0.0020793884,0.0079431,0.00032246948,0.00008093335,0.00028500392,0.0025198383,0.00030340705,0.01324786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931693,0.00007244099,0.000070504364,0.00012520334,0.00031268477,0.00010217084],"domain_scores_gemma":[0.9996123,0.000040183433,0.00014898196,0.000027067357,0.000026495572,0.00014515544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037155984,0.0019263213,0.0008887584,0.0019242218,0.0005300963,0.0006058805,0.0005082127,0.0015261119,0.005400826],"category_scores_gemma":[0.000277049,0.00075277797,0.00054158043,0.0005402106,0.0009759802,0.00035196636,0.0006644049,0.0012487395,0.0012735915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006064953,0.0001233971,0.00052321196,0.000066517096,0.000023104665,0.0007667276,0.0000322086,0.00008087711,0.995488,0.00023313373,0.00016218262,0.0018940981],"study_design_scores_gemma":[0.0009808369,0.0026029353,0.045732178,0.00013323825,0.00029273742,0.025081765,0.00026815254,0.0034603882,0.9044961,0.0013221999,0.015542815,0.00008666143],"about_ca_topic_score_codex":0.00072846824,"about_ca_topic_score_gemma":0.0015952574,"teacher_disagreement_score":0.005400826,"about_ca_system_score_codex":0.0003308989,"about_ca_system_score_gemma":0.00039195264,"threshold_uncertainty_score":0.018067598},"labels":[],"label_agreement":null},{"id":"W2026165970","doi":"10.1172/jci31810","title":"Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis","year":2007,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; School of Medicine, Stanford University; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Tuberculosis; Mycobacterium tuberculosis; Genomics; Whole genome sequencing; Biology; Genome; Medicine; Computational biology; Genetics; Gene; Pathology","score_opus":0.18559388424742024,"score_gpt":0.46891330473376674,"score_spread":0.2833194204863465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026165970","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000057257737,0.99857664,0.00008546117,0.0005611269,0.00016487626,0.0000020794323,0.0000032679948,0.0000033777183,0.0005459795],"genre_scores_gemma":[0.00030373514,0.9989737,0.00013852889,0.00018033369,0.00018385696,0.0000022471845,0.0000055934847,4.908744e-7,0.00021155634],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99961686,0.00011427014,0.000042794498,0.00004462575,0.00015106909,0.000030281373],"domain_scores_gemma":[0.9993994,0.00032204195,0.00006594233,0.000018861685,0.00014313235,0.000050679264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001011379,0.0007028412,0.0015884566,0.0025560474,0.00034902626,0.0010791149,0.00085875374,0.0020947272,0.0018822342],"category_scores_gemma":[0.0013875755,0.0003512743,0.00039137877,0.0028271812,0.0010852654,0.0018071618,0.0006776168,0.0020819006,0.0023111007],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006512083,0.00008736764,0.00043611473,0.007731307,0.000077130215,0.00043251106,0.000115758776,0.00035175748,0.001544976,0.007603779,0.035198323,0.9463558],"study_design_scores_gemma":[0.000018347018,0.00006141184,0.0019991524,0.0035916716,0.000048985694,0.0026464139,0.00013579203,0.00007218934,0.0003572553,0.0048964447,0.9861508,0.000021470507],"about_ca_topic_score_codex":0.0019256896,"about_ca_topic_score_gemma":0.0026269446,"teacher_disagreement_score":0.0025560474,"about_ca_system_score_codex":0.0010174032,"about_ca_system_score_gemma":0.0016002998,"threshold_uncertainty_score":0.0073818564},"labels":[],"label_agreement":null},{"id":"W2026196869","doi":"10.1172/jci32249","title":"Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone–binding globulin gene","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":226,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Child and Family Research Institute","keywords":"Sex hormone-binding globulin; Lipogenesis; Endocrinology; Internal medicine; Monosaccharide; Biology; Downregulation and upregulation; Hepatocyte nuclear factors; Hepatocyte; Hormone; Chemistry; Transcription factor; Lipid metabolism; Biochemistry; Medicine; Gene; Androgen","score_opus":0.10331899300080868,"score_gpt":0.397070255528934,"score_spread":0.29375126252812533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026196869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99516535,0.0025357888,0.001119341,0.000079299956,0.000021245834,0.000013124666,0.00016326552,0.0000342936,0.0008682763],"genre_scores_gemma":[0.99567515,0.0012215697,0.0007501975,0.000045467143,0.00000947111,0.000014101137,0.00029175286,0.000012601326,0.0019796707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999516,0.000010962504,0.0000024376143,0.000010098689,0.000011404159,0.000013502653],"domain_scores_gemma":[0.9999683,0.0000063811185,0.000009470067,0.000002943131,0.0000057034385,0.0000072791586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000062430474,0.00021190556,0.000090051166,0.00017199873,0.00007949611,0.0001674607,0.000070418464,0.00008647532,0.0008523181],"category_scores_gemma":[0.00006343212,0.00010647038,0.000114089205,0.00007975647,0.00019893145,0.00007572915,0.0001271646,0.00016101355,0.00021032902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021301769,0.00001304635,0.0010793746,0.000014085807,0.0000038996095,0.000049170394,0.00001467879,0.000040833726,0.9964431,0.00010636323,0.000034247958,0.0019881504],"study_design_scores_gemma":[0.000022665621,0.00020181351,0.038013473,0.000004820224,0.000015374078,0.00017615654,0.00004397488,0.00051670615,0.9584612,0.00010314745,0.0024364807,0.0000042007346],"about_ca_topic_score_codex":0.001616456,"about_ca_topic_score_gemma":0.0019511889,"teacher_disagreement_score":0.001616456,"about_ca_system_score_codex":0.00035106976,"about_ca_system_score_gemma":0.00013227978,"threshold_uncertainty_score":0.0032141209},"labels":[],"label_agreement":null},{"id":"W2026858501","doi":"10.1172/jci8858","title":"Targeting the urokinase plasminogen activator receptor enhances gene transfer to human airway epithelia","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Roy J. Carver Charitable Trust; Cystic Fibrosis Foundation; Howard Hughes Medical Institute","keywords":"Urokinase receptor; Urokinase; Receptor; Endocytosis; Cell biology; Plasminogen activator; Biology; Activator (genetics); Plasmin; Genetic enhancement; Molecular biology; Cancer research; Chemistry; Gene; Biochemistry; Endocrinology; Genetics","score_opus":0.051418558140518024,"score_gpt":0.3710018116874486,"score_spread":0.31958325354693057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026858501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855106,0.004743768,0.0060701817,0.0002623275,0.000047606198,0.00006303495,0.000088244924,0.00011591051,0.003098402],"genre_scores_gemma":[0.9878171,0.002578969,0.0068556285,0.000081029255,0.00002581132,0.000032268643,0.00011857409,0.000025251975,0.002465508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99959487,0.00012474121,0.0000212205,0.00004952309,0.00011417613,0.00009548392],"domain_scores_gemma":[0.9998679,0.000054165215,0.000017819631,0.000015851783,0.00001774552,0.000026391725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038122197,0.00022602003,0.00035823937,0.00022761125,0.00018927942,0.00065059605,0.00012927371,0.00037796368,0.0015905215],"category_scores_gemma":[0.00020716603,0.00012048293,0.000255741,0.00013980061,0.00031914332,0.0003206741,0.00046265166,0.000591815,0.0005614517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035235604,0.000026058975,0.000057479057,0.000024292136,0.000002447751,0.000027771901,0.000014785993,0.000028521112,0.99763656,0.00010222642,0.00003121422,0.0020134414],"study_design_scores_gemma":[0.000011126838,0.0003422653,0.00080767676,0.0000045301476,0.000011209659,0.00013786714,0.000018207065,0.00040508487,0.9957332,0.00003492569,0.002491172,0.000002702708],"about_ca_topic_score_codex":0.00037013282,"about_ca_topic_score_gemma":0.0005529968,"teacher_disagreement_score":0.0015905215,"about_ca_system_score_codex":0.00029747223,"about_ca_system_score_gemma":0.00029786787,"threshold_uncertainty_score":0.005320847},"labels":[],"label_agreement":null},{"id":"W2027658726","doi":"10.1172/jci67201","title":"Whole exome sequencing of adenoid cystic carcinoma","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Salivary Gland Tumors Diagnosis and Treatment","field":"Medicine","cited_by":273,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Research Council Canada; University of Texas MD Anderson Cancer Center; National Cancer Institute; National Institutes of Health; Fonds Wetenschappelijk Onderzoek; Wellcome Trust; Vlaamse regering; Adenoid Cystic Carcinoma Research Foundation","keywords":"Exome sequencing; Biology; CDKN2A; Cancer research; Genetics; Cancer; Adenoid cystic carcinoma; Mutation; PTPN11; Gene; KRAS; Carcinoma","score_opus":0.10571638864368364,"score_gpt":0.36449659580667476,"score_spread":0.2587802071629911,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027658726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97704107,0.0017532731,0.004484248,0.00043295973,0.00008251703,0.00011123436,0.012893761,0.00008062113,0.0031203527],"genre_scores_gemma":[0.972667,0.0012989822,0.0076404484,0.0005229128,0.000044747598,0.00012272324,0.014934435,0.000067950634,0.002700863],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99974555,0.000026866857,0.000028238834,0.00007729007,0.000086322034,0.000035775684],"domain_scores_gemma":[0.9996505,0.00015475624,0.000037470447,0.000045298268,0.00006362701,0.000048352653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028543355,0.0003158766,0.00044336275,0.0010658122,0.0005517264,0.0004937883,0.00022264635,0.0008509905,0.0016333362],"category_scores_gemma":[0.0011835418,0.00013082704,0.00042662452,0.00076313264,0.00016446295,0.00012377191,0.0004237137,0.000373401,0.0004344557],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014712677,0.00022038928,0.101827174,0.00059813086,0.0005553388,0.044382397,0.0011390465,0.0053114933,0.7433988,0.0011301943,0.007858155,0.09210752],"study_design_scores_gemma":[0.00024318129,0.0004852819,0.71886253,0.0002727634,0.0007367053,0.07973262,0.0007657905,0.012116137,0.11835315,0.002144039,0.06615654,0.00013130087],"about_ca_topic_score_codex":0.0022536104,"about_ca_topic_score_gemma":0.005256594,"teacher_disagreement_score":0.0022536104,"about_ca_system_score_codex":0.00039223675,"about_ca_system_score_gemma":0.0002912451,"threshold_uncertainty_score":0.005464077},"labels":[],"label_agreement":null},{"id":"W2027756860","doi":"10.1172/jci30562","title":"The role of CXC chemokines in pulmonary fibrosis","year":2007,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":272,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Fibrocyte; CXC chemokine receptors; Angiogenesis; Chemokine; CXCR3; Progenitor cell; Pulmonary fibrosis; Mesenchymal stem cell; Immunology; Fibrosis; Medicine; Cancer research; Biology; Pathology; Cell biology; Inflammation; Chemokine receptor; Stem cell","score_opus":0.0929449321263822,"score_gpt":0.42575160221394065,"score_spread":0.33280667008755843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027756860","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016658103,0.99849796,0.00007763978,0.00021220828,0.00018809095,0.000002877038,0.000006703146,0.0000042122597,0.0008437787],"genre_scores_gemma":[0.000575713,0.9984459,0.00013047796,0.00012238194,0.00018877749,0.0000043583827,0.000009908925,5.824831e-7,0.0005218555],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99986863,0.000021657104,0.000019692108,0.000019782588,0.000056798814,0.0000134065585],"domain_scores_gemma":[0.999818,0.00007287042,0.00002519634,0.000005734682,0.00005424796,0.00002403291],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039080446,0.00057365024,0.001063715,0.0016496865,0.00030432304,0.000680638,0.00047607545,0.00080087,0.0025311897],"category_scores_gemma":[0.0003832081,0.00015564896,0.0002752316,0.0018122256,0.00037312522,0.0010481112,0.00048004824,0.00096222403,0.0016457833],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056232217,0.00005338536,0.00030127898,0.0076441835,0.000047189573,0.000558961,0.000070902126,0.000274898,0.0034238177,0.0030649486,0.026300939,0.9582032],"study_design_scores_gemma":[0.000018553284,0.00009283811,0.0018285958,0.0027176696,0.00006246901,0.0039998014,0.00008971197,0.00007544333,0.000682071,0.002012978,0.9884029,0.00001713153],"about_ca_topic_score_codex":0.00064766797,"about_ca_topic_score_gemma":0.0011099968,"teacher_disagreement_score":0.0025311897,"about_ca_system_score_codex":0.0003988483,"about_ca_system_score_gemma":0.0009917931,"threshold_uncertainty_score":0.008467734},"labels":[],"label_agreement":null},{"id":"W2028650359","doi":"10.1172/jci42391","title":"Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Ontario Institute for Cancer Research","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto","keywords":"Subclass; Biology; Carcinogenesis; Osteosarcoma; Suppressor; Cancer research; Gene; Cancer; Genetics; Antibody","score_opus":0.09319645429884904,"score_gpt":0.38414028404543443,"score_spread":0.2909438297465854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028650359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96502334,0.0016299092,0.02223512,0.0008679553,0.00009670794,0.00025702605,0.0034965926,0.0011422471,0.0052511473],"genre_scores_gemma":[0.9579002,0.0016750639,0.017804433,0.0002903843,0.000040422565,0.00039444873,0.0029507608,0.00047664257,0.018467722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953175,0.000058420486,0.00005886038,0.00014795763,0.00012341613,0.00007954625],"domain_scores_gemma":[0.99951315,0.00007907206,0.00020309408,0.000066677356,0.000025360636,0.00011255384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040139473,0.0007520736,0.00033424067,0.001987515,0.0005397432,0.0005730813,0.00062268437,0.00090150855,0.004709935],"category_scores_gemma":[0.00020386832,0.0007166274,0.00055935734,0.00038459772,0.0007546951,0.00048492328,0.0005313866,0.002025852,0.0014320688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002696818,0.00012322217,0.0004910322,0.000039491177,0.000009684635,0.00014219664,0.00004171624,0.00012810354,0.9944969,0.0011683215,0.00016037685,0.0029291692],"study_design_scores_gemma":[0.00023902398,0.0008920094,0.0071602855,0.00004670631,0.000050782157,0.0024184273,0.00008238153,0.002775584,0.97268236,0.0007286356,0.012904362,0.00001952332],"about_ca_topic_score_codex":0.00062282267,"about_ca_topic_score_gemma":0.0014696607,"teacher_disagreement_score":0.004709935,"about_ca_system_score_codex":0.00051024696,"about_ca_system_score_gemma":0.00044807268,"threshold_uncertainty_score":0.015756309},"labels":[],"label_agreement":null},{"id":"W2028683699","doi":"10.1172/jci32482","title":"Sizing up sialic acid in glomerular disease","year":2007,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; National Cancer Institute; Kidney Foundation of Canada","keywords":"Sialic acid; Glomerulus; Proteinuria; Lesion; Disease; Glomerulonephritis; Medicine; Chemistry; Biochemistry; Immunology; Biology; Internal medicine; Pathology; Kidney","score_opus":0.09702591322263254,"score_gpt":0.4009249863074031,"score_spread":0.30389907308477054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028683699","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00809847,0.022294788,0.00062904676,0.9211752,0.03614102,0.00003966771,0.000040648003,0.00011764054,0.011463629],"genre_scores_gemma":[0.089240044,0.024116633,0.0010687553,0.70315146,0.1693923,0.00006236572,0.00004792826,0.000032854743,0.012887655],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994481,0.00020694689,0.00006404176,0.00005055931,0.00015660953,0.0000737474],"domain_scores_gemma":[0.9990097,0.0005763389,0.00005394055,0.000048820628,0.0001528978,0.00015821202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088508864,0.00064261875,0.0008602237,0.00045103303,0.0010908673,0.00097634766,0.00057725044,0.012232716,0.0023058895],"category_scores_gemma":[0.0034672802,0.00026746496,0.0004893813,0.00026766828,0.0011700396,0.0013017011,0.00040246506,0.007702215,0.002089148],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045597073,0.00023537959,0.0037293904,0.00029994457,0.000056724908,0.03721962,0.00019140661,0.00020290466,0.0027502475,0.007207896,0.8859027,0.06174781],"study_design_scores_gemma":[0.0010935095,0.0006011942,0.00534134,0.00066892017,0.00012138476,0.09706463,0.00049912435,0.0016346081,0.002428887,0.025540467,0.8649264,0.000079500765],"about_ca_topic_score_codex":0.0004727571,"about_ca_topic_score_gemma":0.0011563473,"teacher_disagreement_score":0.012232716,"about_ca_system_score_codex":0.001247931,"about_ca_system_score_gemma":0.0005265117,"threshold_uncertainty_score":0.009054363},"labels":[],"label_agreement":null},{"id":"W2029190746","doi":"10.1172/jci14817","title":"Parathyroid hormone is essential for normal fetal bone formation","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":232,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Jewish General Hospital; McGill University","funders":"Medical Research Council","keywords":"Internal medicine; Endocrinology; Parathyroid hormone; Fetus; Anabolism; Cartilage; Ossification; Teriparatide; Long bone; Chemistry; Medicine; Biology; Anatomy; Calcium; Pregnancy","score_opus":0.11568784558306382,"score_gpt":0.39960700421157735,"score_spread":0.2839191586285135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029190746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9554905,0.021858152,0.0096574165,0.0007920183,0.00015702735,0.000054371165,0.0014835375,0.0006904612,0.009816381],"genre_scores_gemma":[0.9909117,0.0035487108,0.0025571596,0.0000611929,0.000037343736,0.000023602206,0.0005418533,0.000046460984,0.0022719176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963737,0.000049923045,0.000031831525,0.00005077997,0.00018013282,0.00004993833],"domain_scores_gemma":[0.99952257,0.00011543963,0.00009297702,0.00006490719,0.00007628835,0.00012792317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018882014,0.0002052694,0.00023696241,0.0003153007,0.00019082591,0.00049054215,0.00030660562,0.00035848533,0.0013526698],"category_scores_gemma":[0.0007025235,0.00026145543,0.00012406637,0.00011289046,0.00036460345,0.00019099866,0.00033647884,0.0004227452,0.0006246337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024200128,0.000015918858,0.0011284563,0.000079052355,0.00000537859,0.00046322084,0.000035404268,0.00008280367,0.98921543,0.000569073,0.00020143035,0.007961813],"study_design_scores_gemma":[0.000113077345,0.00054379815,0.04548657,0.000057703663,0.000048807644,0.006099504,0.00012598578,0.00093045464,0.90436447,0.0013287509,0.040879264,0.000021551386],"about_ca_topic_score_codex":0.00088683434,"about_ca_topic_score_gemma":0.0007448029,"teacher_disagreement_score":0.0013526698,"about_ca_system_score_codex":0.00032735418,"about_ca_system_score_gemma":0.00043200262,"threshold_uncertainty_score":0.004525125},"labels":[],"label_agreement":null},{"id":"W2029669172","doi":"10.1172/jci14205","title":"Linking a serotonin transporter polymorphism to vascular smoothmuscle proliferation in patients with primary pulmonary hypertension","year":2001,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"","keywords":"BMPR2; Pulmonary hypertension; Bone morphogenetic protein receptor; Serotonin transporter; Bone morphogenetic protein; Pathophysiology; Medicine; Disease; Genetic disorder; Bioinformatics; Receptor; Heart disease; Endocrinology; Internal medicine; Serotonin; Biology; Genetics; Gene","score_opus":0.09914885493717085,"score_gpt":0.3619134816496382,"score_spread":0.26276462671246736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029669172","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010167086,0.99675,0.00015027281,0.0004369972,0.00016991982,0.000004840643,0.000023046576,0.000009701523,0.0014385537],"genre_scores_gemma":[0.006665992,0.9911644,0.00026958057,0.00035391943,0.00039909838,0.000009338065,0.000045798042,0.0000013026793,0.0010905974],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99987745,0.000029083381,0.00002011345,0.000022030345,0.000041919153,0.000009275046],"domain_scores_gemma":[0.9997869,0.000101431535,0.000034920737,0.00000486436,0.000047894864,0.000024027879],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030085578,0.0004925332,0.0012143267,0.0011417869,0.00018401165,0.00035874842,0.0004547555,0.0007370892,0.002960072],"category_scores_gemma":[0.00057051796,0.00012421588,0.00017865554,0.001061087,0.00026429506,0.00038310274,0.0001682103,0.0004892402,0.0017299092],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023971527,0.00006583292,0.0026546489,0.0061871097,0.00010196442,0.002398064,0.000059322254,0.00013300899,0.0017013026,0.0005608779,0.02011492,0.96578324],"study_design_scores_gemma":[0.0002685788,0.0007432422,0.03647266,0.005356748,0.00088922726,0.052449275,0.00028252965,0.00029458478,0.0021003913,0.0017825271,0.89930654,0.000053786447],"about_ca_topic_score_codex":0.001250594,"about_ca_topic_score_gemma":0.0021972249,"teacher_disagreement_score":0.002960072,"about_ca_system_score_codex":0.00026090807,"about_ca_system_score_gemma":0.0004929991,"threshold_uncertainty_score":0.009902477},"labels":[],"label_agreement":null},{"id":"W2029883816","doi":"10.1172/jci8829","title":"Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":1175,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; University of Toronto; Hospital for Sick Children","funders":"National Institutes of Health; National Cancer Institute; Cancer Care Ontario","keywords":"Medicine; Vinblastine; Pharmacology; Angiogenesis; Chemotherapy; In vivo; Cancer research; Toxicity; Combination therapy; Oncology; Internal medicine; Biology","score_opus":0.04590777157183174,"score_gpt":0.3935550668225939,"score_spread":0.34764729525076216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029883816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919668,0.0026987796,0.0020829167,0.000087381595,0.0000708471,0.000098543605,0.00031445542,0.0001655942,0.0025146957],"genre_scores_gemma":[0.99333113,0.0007497476,0.0027486042,0.00004211366,0.000025554727,0.00008341344,0.00051192264,0.000020792317,0.0024866594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998087,0.00003217837,0.00001535754,0.000040016777,0.000052990614,0.000050647446],"domain_scores_gemma":[0.99986947,0.000027064667,0.000026395566,0.000019269446,0.000008795053,0.000049051312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017193347,0.00029366947,0.0004911225,0.00023229315,0.00014116992,0.0003246175,0.0003219039,0.00021004505,0.0012484613],"category_scores_gemma":[0.0001311613,0.00010981225,0.00014369411,0.00018962754,0.0002441432,0.00016211072,0.00017271066,0.00072140084,0.00027222573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006306881,0.0006747306,0.00049623783,0.00006183792,0.000015748295,0.00004472129,0.000023076442,0.00018192464,0.98907053,0.00014654262,0.00036492047,0.008289021],"study_design_scores_gemma":[0.0002561912,0.0050886897,0.007522353,0.000010639113,0.000037801507,0.00031673128,0.000022216616,0.0016733208,0.9782914,0.000038556223,0.006734498,0.0000077128125],"about_ca_topic_score_codex":0.0010216385,"about_ca_topic_score_gemma":0.003849312,"teacher_disagreement_score":0.0012484613,"about_ca_system_score_codex":0.00045441985,"about_ca_system_score_gemma":0.00041039818,"threshold_uncertainty_score":0.0041764975},"labels":[],"label_agreement":null},{"id":"W2030780996","doi":"10.1172/jci60005","title":"Viruses and human brain tumors: cytomegalovirus enters the fray","year":2011,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University Health Network","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; National Brain Tumor Society","keywords":"Medulloblastoma; Cytomegalovirus; Human cytomegalovirus; Medicine; Oncology; Virus; Immunology; Internal medicine; Virology; Cancer research; Biology; Herpesviridae; Viral disease","score_opus":0.16509286066408507,"score_gpt":0.4180852797420965,"score_spread":0.25299241907801145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030780996","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010245615,0.039935578,0.00059892994,0.9021948,0.030246451,0.000032402062,0.0000490437,0.00010171332,0.016595498],"genre_scores_gemma":[0.093629025,0.05012373,0.00096734177,0.5656337,0.2657515,0.000055515262,0.000074366595,0.00004993546,0.023714934],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99921894,0.00030674256,0.00007008492,0.000077496334,0.00021464644,0.000112115595],"domain_scores_gemma":[0.9990231,0.0005917843,0.000099590274,0.0000423448,0.00012186658,0.00012139379],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061397115,0.00077367533,0.000838376,0.00051428925,0.0013126201,0.0019524957,0.0006236685,0.01657303,0.0033417237],"category_scores_gemma":[0.0042524403,0.00033721584,0.0005933498,0.0004110266,0.0017168974,0.0022204057,0.00063416385,0.008464248,0.0026753421],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033664,0.00016482804,0.008294587,0.0004973153,0.000059026315,0.09333012,0.0005802855,0.00032751253,0.0034456782,0.009465148,0.8044057,0.07909321],"study_design_scores_gemma":[0.00019629503,0.0002746287,0.0037844095,0.0005836182,0.000058858477,0.13321799,0.0007246762,0.0008483825,0.0013809118,0.013649768,0.84522456,0.000055945675],"about_ca_topic_score_codex":0.0016605242,"about_ca_topic_score_gemma":0.001891249,"teacher_disagreement_score":0.01657303,"about_ca_system_score_codex":0.0020077378,"about_ca_system_score_gemma":0.0006685669,"threshold_uncertainty_score":0.014567196},"labels":[],"label_agreement":null},{"id":"W2030802073","doi":"10.1172/jci34753","title":"Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":334,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"EIF4E; Initiation factor; Eukaryotic initiation factor; Eukaryotic translation; Translation (biology); EIF4A1; Biology; eIF4A; Cancer research; Tensin; eIF2; Internal ribosome entry site; Eukaryotic translation initiation factor 4 gamma; Ribosome; PTEN; Cell biology; Messenger RNA; RNA; Genetics; PI3K/AKT/mTOR pathway; Gene; Signal transduction","score_opus":0.11562283011825328,"score_gpt":0.36330825035942327,"score_spread":0.24768542024117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030802073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957443,0.00071702123,0.0013265286,0.00018737734,0.00003965789,0.00008453882,0.00030454516,0.00016322004,0.001432808],"genre_scores_gemma":[0.9950185,0.000687916,0.0014987707,0.00006748483,0.000018161649,0.00009857142,0.00042516043,0.000020570604,0.002164887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997888,0.000050024177,0.000016583845,0.00003476638,0.000050834577,0.000058957157],"domain_scores_gemma":[0.9998282,0.000036313042,0.00005361717,0.000019685078,0.0000136438575,0.00004854067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002874024,0.0005044285,0.00035120882,0.00074076606,0.00021096149,0.00029990214,0.0002956083,0.00041395923,0.0013269319],"category_scores_gemma":[0.0001496635,0.00018528792,0.0002544151,0.00029962778,0.00034919017,0.0002826082,0.00014496534,0.0011019197,0.00022386711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047557,0.00038249185,0.00017055107,0.00002205699,0.0000073530828,0.000041272495,0.00001569768,0.00011807657,0.9971163,0.00013564955,0.000066647444,0.0014482354],"study_design_scores_gemma":[0.00009640135,0.0022696347,0.0014063322,0.0000048932134,0.000020159776,0.00008774539,0.000013389791,0.0011381925,0.9940705,0.00005046517,0.00083752826,0.000004896911],"about_ca_topic_score_codex":0.00063817395,"about_ca_topic_score_gemma":0.001284759,"teacher_disagreement_score":0.0013269319,"about_ca_system_score_codex":0.00047379403,"about_ca_system_score_gemma":0.0002466097,"threshold_uncertainty_score":0.0044389963},"labels":[],"label_agreement":null},{"id":"W2031472162","doi":"10.1172/jci37914","title":"Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":197,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institutes of Health; Multiple Sclerosis Society; Mary E. Groff Surgical and Medical Research and Education Charitable Trust; National Multiple Sclerosis Society","keywords":"Remyelination; Neural stem cell; Biology; Secretion; Cell biology; Stem cell; Myelin; Immunology; Multiple sclerosis; Neuroscience; Biochemistry; Central nervous system","score_opus":0.09647139142671014,"score_gpt":0.34802595748191106,"score_spread":0.25155456605520093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031472162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99459594,0.0016008338,0.0013885795,0.00008373451,0.00006266044,0.000045219782,0.00012506783,0.00008502702,0.0020131723],"genre_scores_gemma":[0.99139684,0.0023177436,0.0025877436,0.000080026606,0.000027237602,0.00006149156,0.00036944193,0.000012429724,0.0031470559],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988914,0.000023793878,0.00001531941,0.0000120003315,0.000033231696,0.000026448399],"domain_scores_gemma":[0.9999461,0.00001081927,0.000010880764,0.0000062562453,0.000007789032,0.000018263796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017934268,0.000403218,0.00022655983,0.0003419943,0.00007341674,0.00021355865,0.00014093536,0.0002512033,0.0009100131],"category_scores_gemma":[0.00011192748,0.00009654551,0.0001306291,0.00009964827,0.00024863135,0.00015421333,0.00013812113,0.0005605991,0.00024507302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024271145,0.00018418454,0.0002121213,0.000059690614,0.000006439434,0.00007544888,0.000019554027,0.00010034885,0.99479115,0.00010623309,0.00005823642,0.004143897],"study_design_scores_gemma":[0.00010844698,0.0016180588,0.0040583834,0.000026266229,0.00004274992,0.00032079357,0.00003488891,0.0009953339,0.9895035,0.00011277184,0.0031740991,0.0000048290876],"about_ca_topic_score_codex":0.00041929842,"about_ca_topic_score_gemma":0.0009731019,"teacher_disagreement_score":0.0009100131,"about_ca_system_score_codex":0.00015033013,"about_ca_system_score_gemma":0.00020729683,"threshold_uncertainty_score":0.0030443072},"labels":[],"label_agreement":null},{"id":"W2031674672","doi":"10.1172/jci65833","title":"Prognostically relevant gene signatures of high-grade serous ovarian carcinoma","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":591,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Calgary","funders":"National Human Genome Research Institute; National Institute of General Medical Sciences; Duke-NUS Medical School; Medical Research Council; National Health and Medical Research Council; National Cancer Institute; Foundation Medicine; National Institutes of Health","keywords":"Oncology; Ovarian cancer; Internal medicine; Medicine; Serous carcinoma; Serous fluid; Context (archaeology); Ovarian carcinoma; Disease; Prognostic variable; Cancer; Bioinformatics; Biology","score_opus":0.0778061322023824,"score_gpt":0.36296631908472043,"score_spread":0.285160186882338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031674672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990753,0.00017172424,0.00021629925,0.00002878681,0.0000025598574,0.000003824156,0.00033282407,0.000008349348,0.00016033776],"genre_scores_gemma":[0.9992679,0.000047648053,0.0001789837,0.0000109634,0.0000026511625,0.0000026016478,0.0004501467,0.0000014200358,0.000037729216],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998456,0.000047988437,0.000015020532,0.000021716127,0.000033107077,0.000036500747],"domain_scores_gemma":[0.9994628,0.00017954195,0.0001944274,0.000049135604,0.000051791638,0.00006232214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032607964,0.00015934586,0.00025398514,0.0006780919,0.00016473462,0.0005483859,0.000103462684,0.0002079275,0.00033850342],"category_scores_gemma":[0.0012017506,0.00007719718,0.00018927366,0.000788157,0.00019739478,0.00011042833,0.00022537207,0.00018689835,0.00009409439],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003560572,0.00002450619,0.98085564,0.000021753998,0.0000466991,0.00012135048,0.000040886734,0.0011407093,0.009608123,0.000053066706,0.00019981762,0.007531396],"study_design_scores_gemma":[0.000012338671,0.00007840323,0.9931745,0.000005592706,0.000052623283,0.0003466296,0.00008846019,0.003807288,0.0017852902,0.00025136166,0.0003913688,0.000006113925],"about_ca_topic_score_codex":0.0010992335,"about_ca_topic_score_gemma":0.0025568728,"teacher_disagreement_score":0.0010992335,"about_ca_system_score_codex":0.0001669128,"about_ca_system_score_gemma":0.0002205807,"threshold_uncertainty_score":0.0021856427},"labels":[],"label_agreement":null},{"id":"W2032138405","doi":"10.1172/jci62185","title":"MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Anodic Oxide Films and Nanostructures","field":"Materials Science","cited_by":266,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Bell (Canada); McGill University; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Institut de Cardiologie de Montréal; Fondation Leducq; National Natural Science Foundation of China; Heart and Stroke Foundation of Canada","keywords":"Gene knockdown; Downregulation and upregulation; Transcription factor; Inward-rectifier potassium ion channel; Internal medicine; NFAT; Regulator; Chemistry; Potassium channel; Endocrinology; Biology; Cell biology; Medicine; Ion channel; Gene; Receptor; Biochemistry","score_opus":0.05594834884251098,"score_gpt":0.34099590711064703,"score_spread":0.28504755826813605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032138405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98350096,0.0066027706,0.004393669,0.00024184138,0.00023634889,0.00010183413,0.00055175234,0.00014922282,0.0042217122],"genre_scores_gemma":[0.99313897,0.0018317277,0.0019565653,0.00013107056,0.00003799475,0.0000700995,0.0003408336,0.000028896307,0.0024637945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998758,0.000021240152,0.000016391032,0.000038395276,0.000024820582,0.000023314711],"domain_scores_gemma":[0.99991965,0.000010324866,0.000027435732,0.00000757812,0.00000915944,0.000025836534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001859745,0.00026768818,0.00029756952,0.00014105649,0.00022081344,0.00031113063,0.00010545128,0.00025855924,0.0013424264],"category_scores_gemma":[0.00019035359,0.00015840662,0.00019568775,0.00008957353,0.00025348703,0.0001472233,0.0001577759,0.00050295144,0.0005190503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000646531,0.00006511409,0.0018079064,0.00008095653,0.000010011887,0.00033785112,0.000035912566,0.000096368116,0.9938226,0.00023839695,0.00017379031,0.0026846107],"study_design_scores_gemma":[0.00016723863,0.0014673675,0.061860424,0.00003458482,0.00010039817,0.0034258997,0.00015245225,0.0021780343,0.91244274,0.00041101268,0.017731419,0.000028346785],"about_ca_topic_score_codex":0.000107978085,"about_ca_topic_score_gemma":0.00019332927,"teacher_disagreement_score":0.0013424264,"about_ca_system_score_codex":0.0001697508,"about_ca_system_score_gemma":0.00019971428,"threshold_uncertainty_score":0.0044908524},"labels":[],"label_agreement":null},{"id":"W2032760353","doi":"10.1172/jci23683","title":"Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institutes of Health; National Institute of General Medical Sciences; Queen's University; University of Pennsylvania","keywords":"Luteolysis; Platelet; Endocrinology; Internal medicine; Thromboxane A2; Aspirin; Thromboxane-A synthase; Thromboxane; Preeclampsia; Prostaglandin; Platelet activation; Medicine; Receptor; Biology; Pregnancy; Corpus luteum; Ovary","score_opus":0.050830465635370456,"score_gpt":0.38516132413207393,"score_spread":0.33433085849670346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032760353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875733,0.00300315,0.0036304188,0.0002685616,0.00016866576,0.0001205855,0.0014717035,0.00024589428,0.0035177025],"genre_scores_gemma":[0.9897481,0.0014761371,0.0018444747,0.00013051437,0.000018920788,0.00017569074,0.0008637265,0.000037342743,0.005705128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996855,0.000035514782,0.00003669012,0.00008195692,0.00009507712,0.0000652364],"domain_scores_gemma":[0.9998472,0.00002634556,0.000046641853,0.000016255504,0.000012071796,0.00005151996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018375338,0.00027638048,0.0003858592,0.00018714355,0.00012842387,0.00037610723,0.00022076395,0.00036141466,0.0015478521],"category_scores_gemma":[0.00013454145,0.00015737143,0.0002300915,0.00014576734,0.00027380415,0.00018422987,0.00019113184,0.0007061562,0.00031654403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037506787,0.000058411275,0.00022156733,0.000071385664,0.000011020389,0.00007894088,0.000028346582,0.00009596542,0.9962006,0.00023649009,0.00016111466,0.0024611314],"study_design_scores_gemma":[0.00007621368,0.0011187679,0.0069476487,0.000011645201,0.000049366354,0.00023926063,0.000055341872,0.0014370349,0.98495317,0.00008462983,0.0050174026,0.000009546978],"about_ca_topic_score_codex":0.0005829844,"about_ca_topic_score_gemma":0.0012146201,"teacher_disagreement_score":0.0015478521,"about_ca_system_score_codex":0.00027830413,"about_ca_system_score_gemma":0.00024213169,"threshold_uncertainty_score":0.0051780343},"labels":[],"label_agreement":null},{"id":"W2034223507","doi":"10.1172/jci39715","title":"PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":245,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre; McGill University Health Centre","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Deafness and Other Communication Disorders; National Institutes of Health; Deutsche Forschungsgemeinschaft; American Heart Association","keywords":"Usher syndrome; Retinitis pigmentosa; Biology; Genetics; Missense mutation; Zebrafish; Retinal degeneration; Compound heterozygosity; Mutation; Phenotype; Genetic heterogeneity; Gene","score_opus":0.10326346366200459,"score_gpt":0.38689034224426394,"score_spread":0.2836268785822593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034223507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896561,0.0013582325,0.004780379,0.0002817649,0.000047009213,0.000037982656,0.00088043016,0.0001640221,0.0027940923],"genre_scores_gemma":[0.99458957,0.0007715583,0.002440635,0.000108558095,0.000013717998,0.000019706104,0.00065028446,0.000025883775,0.0013799192],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998197,0.000019882636,0.000018343453,0.00005699484,0.00006629581,0.000018842931],"domain_scores_gemma":[0.9998747,0.000035052668,0.000039626233,0.000010223931,0.000014051727,0.000026370166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105082,0.00059472787,0.00027913108,0.0011017433,0.00034329836,0.00016808204,0.00030221438,0.00044505103,0.0029720992],"category_scores_gemma":[0.00036357448,0.00018897376,0.0002520966,0.00040209503,0.0003457183,0.00012611438,0.00052224996,0.00040491432,0.0003044037],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042434756,0.0000708153,0.035104312,0.0001821118,0.0001140925,0.03005063,0.00015842034,0.00039092786,0.91151977,0.0018752835,0.00077569624,0.019333689],"study_design_scores_gemma":[0.00027804816,0.00064869603,0.30106476,0.00018169158,0.0007461805,0.19353333,0.00041832108,0.008517795,0.46097443,0.0021991385,0.031343326,0.00009425864],"about_ca_topic_score_codex":0.0007496429,"about_ca_topic_score_gemma":0.0009836827,"teacher_disagreement_score":0.0029720992,"about_ca_system_score_codex":0.00021463649,"about_ca_system_score_gemma":0.00023858197,"threshold_uncertainty_score":0.009942651},"labels":[],"label_agreement":null},{"id":"W2034769761","doi":"10.1172/jci14498","title":"The clinical relevance of glycobiology","year":2001,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation","funders":"","keywords":"Glycobiology; Relevance (law); Computational biology; Medicine; Computer science; Biology; Glycan; Political science; Biochemistry","score_opus":0.10344461987563468,"score_gpt":0.42655168550904565,"score_spread":0.32310706563341096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034769761","genre_codex":"review","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028138235,0.6591888,0.01131162,0.07771474,0.0072464645,0.00010660647,0.0010135175,0.0002493462,0.21503061],"genre_scores_gemma":[0.5247092,0.3912436,0.010264996,0.032866783,0.01888225,0.00012394525,0.0009776935,0.00019287117,0.02073874],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994549,0.0001684242,0.00004276419,0.00009444958,0.00015717064,0.00008233366],"domain_scores_gemma":[0.9986639,0.0005914644,0.00014335843,0.00013723392,0.00026769345,0.00019633271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010441198,0.0004047239,0.0005644918,0.0009806653,0.0005838286,0.0016645945,0.00050267583,0.0018666054,0.015803335],"category_scores_gemma":[0.0045620645,0.0001319803,0.00023248348,0.00092473754,0.0016424585,0.002152145,0.0010623913,0.0022818574,0.003990678],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006984382,0.00016827833,0.027030243,0.0019039152,0.00010136184,0.030639753,0.00041672494,0.00057346857,0.0072778095,0.09168514,0.1650049,0.67449987],"study_design_scores_gemma":[0.00010680382,0.00039747957,0.024372384,0.0059847645,0.00011021412,0.22562341,0.0009680134,0.0007061621,0.0025787277,0.106360026,0.6326929,0.00009916361],"about_ca_topic_score_codex":0.00045291407,"about_ca_topic_score_gemma":0.0004012379,"teacher_disagreement_score":0.015803335,"about_ca_system_score_codex":0.0008435127,"about_ca_system_score_gemma":0.00082979194,"threshold_uncertainty_score":0.052867413},"labels":[],"label_agreement":null},{"id":"W2034986487","doi":"10.1172/jci22831","title":"Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":429,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; York University; University of Minnesota; National Institutes of Health; Alzheimer's Association","keywords":"Rolipram; Long-term potentiation; CREB; Neuroscience; Synaptic plasticity; Protein kinase A; Neurotransmission; Donepezil; Alzheimer's disease; Presenilin; Phosphodiesterase; Pharmacology; Medicine; Chemistry; Biology; Internal medicine; Cell biology; Phosphorylation; Biochemistry; Receptor; Dementia; Disease; Enzyme","score_opus":0.13273456056925528,"score_gpt":0.40745234143284087,"score_spread":0.27471778086358556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034986487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948315,0.0016439478,0.001150467,0.00024927428,0.00007886427,0.000039437684,0.00027327496,0.00037138464,0.0013619541],"genre_scores_gemma":[0.99014497,0.0014100671,0.0022497764,0.00014732193,0.00005592856,0.00011029715,0.00059285475,0.000034454584,0.005254331],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997743,0.000029096747,0.000024393921,0.00003730297,0.000056906654,0.00007801634],"domain_scores_gemma":[0.9997532,0.000014671394,0.00007188353,0.000038850954,0.000027593313,0.000093738236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027944503,0.0008185921,0.0009345026,0.00064747257,0.0002659053,0.0003557081,0.0004391611,0.00077638106,0.0010102094],"category_scores_gemma":[0.00018285346,0.0002258591,0.0004140052,0.00019012288,0.00034430294,0.00043643484,0.00020942393,0.0015110824,0.0005919058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014656436,0.00086719287,0.00043169578,0.00005704036,0.000032709417,0.00049079896,0.000043511172,0.000071483126,0.9895635,0.00010225266,0.00017655078,0.0066976557],"study_design_scores_gemma":[0.0005749791,0.014701109,0.012183581,0.000036278165,0.00015847509,0.0023916385,0.00006861491,0.0016693064,0.96461904,0.00033230017,0.0032377406,0.000026938771],"about_ca_topic_score_codex":0.00054405065,"about_ca_topic_score_gemma":0.0006436016,"teacher_disagreement_score":0.0010102094,"about_ca_system_score_codex":0.0002680452,"about_ca_system_score_gemma":0.00023446779,"threshold_uncertainty_score":0.0033794641},"labels":[],"label_agreement":null},{"id":"W2035729149","doi":"10.1172/jci36551","title":"Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":232,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cancéropôle Ile de France; Institut National Du Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale","keywords":"TLR7; Cancer research; Lung cancer; Biology; Downregulation and upregulation; Immunotherapy; Cell; Immune system; Immunology; Medicine; Pathology; Innate immune system; Toll-like receptor; Gene","score_opus":0.028887337097523405,"score_gpt":0.3334194015012781,"score_spread":0.3045320644037547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035729149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918154,0.0025279422,0.0021669278,0.00015962747,0.000035955025,0.00004256097,0.00030177613,0.000067283174,0.002882489],"genre_scores_gemma":[0.9945996,0.0007975974,0.0015688514,0.00007836701,0.000016404763,0.0000586953,0.0008353299,0.000009446328,0.0020357664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99968565,0.000071081246,0.000021394224,0.000034942586,0.00008678777,0.00010010803],"domain_scores_gemma":[0.9998704,0.00004163717,0.000019050582,0.00002879055,0.000023167304,0.000016992628],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015319779,0.00020215816,0.00027217745,0.00018448263,0.00015771408,0.0003315181,0.00009570834,0.00025423928,0.0030723917],"category_scores_gemma":[0.00022458527,0.00009632885,0.0002439926,0.00015141512,0.00014449417,0.000123618,0.00025055557,0.0004625888,0.001015125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017946702,0.00005234042,0.00039624466,0.000046086723,0.0000057925427,0.000056904784,0.000021389518,0.000060315084,0.9967616,0.00006703462,0.000096015065,0.0022567878],"study_design_scores_gemma":[0.000031460535,0.0007784854,0.004221271,0.000009656574,0.000014177616,0.00047289042,0.000072861236,0.0009099828,0.98920864,0.00006328833,0.0042130905,0.000004185232],"about_ca_topic_score_codex":0.00024818393,"about_ca_topic_score_gemma":0.0003319036,"teacher_disagreement_score":0.0030723917,"about_ca_system_score_codex":0.00020328542,"about_ca_system_score_gemma":0.00017835376,"threshold_uncertainty_score":0.010278165},"labels":[],"label_agreement":null},{"id":"W2036959160","doi":"10.1172/jci38420","title":"Hoofbeats, zebras, and insights into insulin resistance","year":2009,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Robarts Research Institute; U.S. Public Health Service; National Institutes of Health; Ontario Genomics Institute; Ontario Genomics; Genome Canada; Heart and Stroke Foundation of Canada; Pfizer","keywords":"AKT2; Phenotype; Biology; Insulin resistance; Insulin receptor; Gluconeogenesis; Genetics; Serine; Insulin; Gene; Signal transduction; Phosphorylation; PI3K/AKT/mTOR pathway; Endocrinology; AKT1","score_opus":0.032661406726673614,"score_gpt":0.32358078354173864,"score_spread":0.290919376815065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036959160","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018821451,0.011037053,0.00024550618,0.9584583,0.023807589,0.000011686046,0.000023677281,0.000045217526,0.0044887573],"genre_scores_gemma":[0.037786685,0.016680485,0.00065932516,0.7993692,0.13251404,0.000036468035,0.00003223939,0.00003508047,0.0128865],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991867,0.00029728186,0.00008738262,0.0001311841,0.00020123752,0.00009622086],"domain_scores_gemma":[0.99827003,0.0010037551,0.00009680316,0.00009938925,0.00026174347,0.00026838065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010948798,0.0006214467,0.000726148,0.0006256409,0.0013095083,0.0017724253,0.0008557873,0.01296623,0.0030477261],"category_scores_gemma":[0.005438455,0.00037548426,0.00046729174,0.00029973406,0.002053392,0.0017760576,0.00059755915,0.015743233,0.0017672393],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025941158,0.00012093755,0.0025372442,0.000111180445,0.00004242239,0.011400371,0.00015533488,0.00012759234,0.0010214436,0.009941859,0.9393368,0.034945566],"study_design_scores_gemma":[0.000600738,0.00023830935,0.0044645825,0.00041311193,0.00007837413,0.026905356,0.0004803961,0.001451204,0.0016352136,0.038017176,0.92564213,0.00007326468],"about_ca_topic_score_codex":0.0011008417,"about_ca_topic_score_gemma":0.002090972,"teacher_disagreement_score":0.01296623,"about_ca_system_score_codex":0.0016189165,"about_ca_system_score_gemma":0.00062852877,"threshold_uncertainty_score":0.011746168},"labels":[],"label_agreement":null},{"id":"W2037429771","doi":"10.1172/jci59348","title":"Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; BC Cancer Agency; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Cancer Research UK","keywords":"Cancer research; Hedgehog; Hedgehog signaling pathway; Angiogenesis; Biology; Prostate cancer; Tumor progression; GLI1; Sonic hedgehog; Signal transduction; Internal medicine; Endocrinology; Cell biology; Medicine; Cancer; Genetics","score_opus":0.08923130146904419,"score_gpt":0.36316274326613707,"score_spread":0.2739314417970929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037429771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969753,0.0017842437,0.0002606067,0.000078395766,0.000017261993,0.000010969231,0.00008171687,0.000025447034,0.00076604966],"genre_scores_gemma":[0.99759066,0.0009393162,0.00029837815,0.00003257952,0.0000070492297,0.000009921231,0.00020981434,0.0000031286017,0.00090923865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993384,0.000017564977,0.000004901409,0.000008149083,0.000018375351,0.000017145932],"domain_scores_gemma":[0.99995685,0.000010824784,0.000010185841,0.0000031468317,0.0000026807686,0.000016378732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012439463,0.0001971275,0.00021497381,0.00023010817,0.00013257627,0.00023230158,0.0001287251,0.0001418692,0.00080723123],"category_scores_gemma":[0.00012172154,0.00009961635,0.00012202392,0.000119789984,0.00013704902,0.00010374989,0.00010743139,0.00034724217,0.00012827052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001006284,0.0002625188,0.0013175252,0.00007806239,0.000019690935,0.00007577388,0.000015293022,0.0002611238,0.9891907,0.00015734439,0.00015972332,0.007455929],"study_design_scores_gemma":[0.00011601881,0.0031546147,0.02691975,0.0000075648577,0.000038707563,0.00058092864,0.00004544714,0.0017291436,0.9647642,0.00012567172,0.0025116184,0.000006287327],"about_ca_topic_score_codex":0.00038919848,"about_ca_topic_score_gemma":0.0011423228,"teacher_disagreement_score":0.00080723123,"about_ca_system_score_codex":0.00023339718,"about_ca_system_score_gemma":0.00018467588,"threshold_uncertainty_score":0.002700448},"labels":[],"label_agreement":null},{"id":"W2039617287","doi":"10.1172/jci13265","title":"Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":287,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; St. Michael's Hospital; Toronto General Hospital; University of Toronto; Heart and Stroke Foundation","funders":"Medical Research Council; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Peroxynitrite; Heart failure; Myocarditis; Nitric oxide synthase; Dilated cardiomyopathy; Transgene; Genetically modified mouse; Medicine; Cardiomyopathy; Downregulation and upregulation; Sudden death; Sudden cardiac death; Internal medicine; Cardiac fibrosis; Cardiology; Nitric oxide; Biology; Superoxide","score_opus":0.17673042859814994,"score_gpt":0.4099456273707114,"score_spread":0.23321519877256144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039617287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99439573,0.0006291021,0.0034517418,0.00013329828,0.00003591817,0.000042884534,0.00023079282,0.0002079721,0.0008725518],"genre_scores_gemma":[0.99219054,0.00080609095,0.0035221654,0.00011567501,0.000028799006,0.00008980617,0.00046211024,0.00007656706,0.0027082288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961746,0.00008601015,0.000052284442,0.00006791827,0.00006933245,0.00010689866],"domain_scores_gemma":[0.99954563,0.00007168474,0.00016922054,0.00004362707,0.000022316532,0.00014753865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004638253,0.0006288706,0.0003464263,0.00040113958,0.00024340498,0.00029153036,0.0002013362,0.0005406311,0.0013045396],"category_scores_gemma":[0.00025109865,0.00038976638,0.00024299156,0.00016585841,0.00052490167,0.0002866537,0.00024527803,0.0009240646,0.0005209759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000298418,0.00011341217,0.00039133467,0.000028128134,0.0000069029497,0.00017388682,0.0000220807,0.000059903934,0.9976115,0.00016707371,0.00004763658,0.0010797362],"study_design_scores_gemma":[0.00031362276,0.0036129707,0.011508374,0.00003989084,0.00007141991,0.0025774445,0.0000889064,0.0020229379,0.9771335,0.00028634383,0.0023286527,0.000015976902],"about_ca_topic_score_codex":0.00013034938,"about_ca_topic_score_gemma":0.00031247162,"teacher_disagreement_score":0.0013045396,"about_ca_system_score_codex":0.00021029696,"about_ca_system_score_gemma":0.00017782126,"threshold_uncertainty_score":0.004364133},"labels":[],"label_agreement":null},{"id":"W2039970106","doi":"10.1172/jci41024","title":"A view from a European medical academic who spends time in the US","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Health and Medical Research Impacts","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"University of Pennsylvania","keywords":"Health care; Population; Disadvantaged; Medicine; Economic growth; Political science; Law; Environmental health; Economics","score_opus":0.3490166241864983,"score_gpt":0.5465915465808018,"score_spread":0.19757492239430346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039970106","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003059604,0.0061080367,0.00017919471,0.9673361,0.016615706,0.0000023696398,0.000019816034,0.000024304712,0.0094084935],"genre_scores_gemma":[0.007098009,0.0039522382,0.0002713294,0.9681454,0.007777386,0.000010250172,0.000028759601,0.000061704544,0.012654974],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98712873,0.004263639,0.0006974991,0.0018420623,0.0041925446,0.0018756549],"domain_scores_gemma":[0.9791459,0.0031355063,0.0008679463,0.0007328719,0.0064195027,0.009698199],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.010225233,0.0014314533,0.0013794992,0.002018038,0.011092892,0.019526687,0.0025966712,0.026429003,0.022545671],"category_scores_gemma":[0.022242848,0.0005134614,0.0013678982,0.0023041286,0.014201129,0.022904348,0.008844926,0.038678586,0.012059373],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037344555,0.000028179662,0.000317916,0.00007031736,0.000012528499,0.00020774525,0.0021499328,0.00002525151,0.00010257278,0.04246724,0.9436266,0.010954519],"study_design_scores_gemma":[0.0000124306935,0.000022877939,0.00025180128,0.000229076,0.000006745553,0.0002775208,0.0033481226,0.000025950669,0.00004327622,0.008621127,0.9871323,0.000028682833],"about_ca_topic_score_codex":0.010245942,"about_ca_topic_score_gemma":0.012556385,"teacher_disagreement_score":0.026429003,"about_ca_system_score_codex":0.0064514605,"about_ca_system_score_gemma":0.01255674,"threshold_uncertainty_score":0.075422764},"labels":[],"label_agreement":null},{"id":"W2040047122","doi":"10.1172/jci17975","title":"PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Glycogen; Glycogen synthase; Insulin resistance; Internal medicine; Endocrinology; Biology; Glycogen debranching enzyme; Hyperinsulinemia; Insulin receptor; Insulin; Glycogen branching enzyme; Medicine","score_opus":0.04539935447541658,"score_gpt":0.31325581314020307,"score_spread":0.26785645866478647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040047122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99259514,0.00062509085,0.0035706542,0.00014141455,0.00004324531,0.000034245077,0.001086576,0.00034731044,0.0015564958],"genre_scores_gemma":[0.9887101,0.0012872446,0.0030685028,0.000116649026,0.000027252372,0.00007551284,0.0013394516,0.00018361342,0.0051916917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998074,0.000025465424,0.000024296103,0.00005923481,0.000053726093,0.000029831384],"domain_scores_gemma":[0.9996816,0.000053680924,0.00011867186,0.000023437127,0.000012616126,0.000109962544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000140437,0.00086073537,0.00033134464,0.0008285298,0.00017698309,0.00030811387,0.00035531327,0.000584901,0.0030582396],"category_scores_gemma":[0.0002900303,0.00034037788,0.000257428,0.0003520377,0.0006670649,0.00019347717,0.00035819903,0.0006488007,0.00067027484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033069396,0.000067281566,0.00070479984,0.000051911546,0.000017302867,0.0028836904,0.000030631345,0.0002544037,0.9917557,0.0005642315,0.00022350856,0.0031159348],"study_design_scores_gemma":[0.00032432732,0.0013114266,0.029814696,0.00006123163,0.00016195864,0.022308746,0.000110565175,0.0031086067,0.93297315,0.0008426229,0.008939491,0.00004323824],"about_ca_topic_score_codex":0.0005227141,"about_ca_topic_score_gemma":0.00056325994,"teacher_disagreement_score":0.0030582396,"about_ca_system_score_codex":0.0003332302,"about_ca_system_score_gemma":0.00025027385,"threshold_uncertainty_score":0.01023078},"labels":[],"label_agreement":null},{"id":"W2040267618","doi":"10.1172/jci41490","title":"Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University Health Network","funders":"University of Toronto; National Institute of Environmental Health Sciences; Canadian Breast Cancer Research Alliance; V Foundation for Cancer Research; Breast Cancer Research Foundation","keywords":"Cancer research; Biology; Progenitor cell; Breast cancer; Estrogen receptor; Mammary tumor; Tumor suppressor gene; Retinoblastoma; Progesterone receptor; Epithelial–mesenchymal transition; Pathology; Cancer; Stem cell; Carcinogenesis; Metastasis; Medicine; Cell biology; Gene; Genetics","score_opus":0.06079831594064462,"score_gpt":0.3635933413710733,"score_spread":0.3027950254304287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040267618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994504,0.00092743925,0.002528421,0.00009469534,0.000021376127,0.0000474656,0.0005991537,0.00017577043,0.0011017532],"genre_scores_gemma":[0.9933077,0.0007299958,0.0019088226,0.000058879814,0.000010029036,0.000080398466,0.0008943413,0.000055395347,0.0029543848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969673,0.000048314603,0.00004509433,0.00005489683,0.00007284282,0.000082262755],"domain_scores_gemma":[0.99977225,0.000034986828,0.000069171656,0.000035068,0.0000129551545,0.000075640906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002361707,0.00042974256,0.00021559474,0.0004729642,0.00017639478,0.00028537997,0.00026339522,0.0003600861,0.0011046765],"category_scores_gemma":[0.00009736456,0.00028666435,0.0002821481,0.00020891875,0.0002665015,0.00016560113,0.00023761013,0.0008936815,0.0005254075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012679205,0.00003099747,0.00016418145,0.000014854775,0.0000035076046,0.000042769043,0.000015967837,0.000037752547,0.99896514,0.000111227586,0.000016636146,0.00047023702],"study_design_scores_gemma":[0.000021322334,0.00031086258,0.0018156646,0.000005629574,0.000011876271,0.0001790395,0.000023101557,0.00040087957,0.99610424,0.00004117104,0.0010835162,0.0000026344774],"about_ca_topic_score_codex":0.00059376017,"about_ca_topic_score_gemma":0.00061353476,"teacher_disagreement_score":0.0011046765,"about_ca_system_score_codex":0.0002555353,"about_ca_system_score_gemma":0.00024536246,"threshold_uncertainty_score":0.0036955476},"labels":[],"label_agreement":null},{"id":"W2040834736","doi":"10.1172/jci34653","title":"The American Society for Clinical Investigation, 1952–1975: a personal perspective","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Health and Medical Research Impacts","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Perspective (graphical); TRACE (psycholinguistics); Quarter (Canadian coin); Focus (optics); Sociology; Environmental ethics; History; Philosophy","score_opus":0.47757199689291685,"score_gpt":0.5688279684160146,"score_spread":0.09125597152309772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040834736","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0071699154,0.11774361,0.00057677197,0.7850015,0.0131795155,0.000016524738,0.00007476262,0.00001622626,0.07622115],"genre_scores_gemma":[0.3283739,0.28138041,0.002006115,0.299122,0.06375936,0.00013013493,0.00012023616,0.00005278266,0.025055138],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99433833,0.0029860302,0.0004715891,0.00043326736,0.0010305995,0.0007400306],"domain_scores_gemma":[0.9856747,0.0074770045,0.0011593672,0.00031080158,0.002007937,0.0033700936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.012212888,0.00034151197,0.00030100296,0.0031842447,0.0062669264,0.00960952,0.0007953645,0.006691504,0.0026375756],"category_scores_gemma":[0.015816625,0.0003129641,0.00018875605,0.0034302347,0.014375321,0.0044247233,0.003039937,0.012338487,0.00057028065],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007764808,0.00010903606,0.015606337,0.00031274563,0.000032481898,0.0021656603,0.044246957,0.0002138378,0.00044257505,0.3565789,0.49581215,0.084401645],"study_design_scores_gemma":[0.000005557679,0.000022210499,0.0047749537,0.0005082647,0.000005694925,0.0007105967,0.017322581,0.0000332464,0.000060893602,0.014133823,0.96239287,0.000029251501],"about_ca_topic_score_codex":0.019890523,"about_ca_topic_score_gemma":0.04429335,"teacher_disagreement_score":0.019890523,"about_ca_system_score_codex":0.00765875,"about_ca_system_score_gemma":0.012466356,"threshold_uncertainty_score":0.064588666},"labels":[],"label_agreement":null},{"id":"W2041119309","doi":"10.1172/jci27019","title":"Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":517,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"Canadian Institutes of Health Research; University of Toronto; Heart and Stroke Foundation of Canada","keywords":"Bone marrow; Angiogenesis; Cancer research; Stem cell; Progenitor cell; Bone Marrow Stem Cell; Medicine; Endothelial stem cell; Biology; Cell biology; Immunology","score_opus":0.05326937716415785,"score_gpt":0.3334121574768757,"score_spread":0.28014278031271783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041119309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9688523,0.020445123,0.0045531145,0.0005340566,0.00008146501,0.0001755176,0.00022117388,0.00014959792,0.0049877535],"genre_scores_gemma":[0.9880553,0.004878103,0.0034923388,0.00026751446,0.000097413016,0.00009500873,0.0002945599,0.000024186651,0.002795594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998809,0.000026576192,0.000009273398,0.000015499641,0.000038588634,0.000029024744],"domain_scores_gemma":[0.99992585,0.000012564666,0.000018918365,0.0000065186427,0.0000104876535,0.000025668902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002337426,0.00026125807,0.000282288,0.00023244979,0.00007673911,0.00037501182,0.00010816925,0.00018859432,0.001590576],"category_scores_gemma":[0.0001827297,0.00009667412,0.00008379467,0.00010084259,0.00018483971,0.000104289786,0.00014292599,0.00053233537,0.00045614413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035408812,0.000053538137,0.00074970064,0.00008284442,0.000005830809,0.00009342605,0.000019513089,0.000059070204,0.9767923,0.00036032542,0.00018310294,0.021246366],"study_design_scores_gemma":[0.0005101078,0.0021282535,0.030266719,0.00009202765,0.00011264824,0.0017640721,0.000080917715,0.0013919179,0.93916893,0.0005424783,0.023933005,0.00000897245],"about_ca_topic_score_codex":0.00015088373,"about_ca_topic_score_gemma":0.00034309272,"teacher_disagreement_score":0.001590576,"about_ca_system_score_codex":0.00010594052,"about_ca_system_score_gemma":0.00018104656,"threshold_uncertainty_score":0.005321026},"labels":[],"label_agreement":null},{"id":"W2041249840","doi":"10.1172/jci24311","title":"Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense; National Heart, Lung, and Blood Institute; American Heart Association","keywords":"Hairless; Notch signaling pathway; Biology; Cell biology; Vascular endothelial growth factor C; Endothelial stem cell; Lymphangiogenesis; Lymphatic Endothelium; Endothelium; Cancer research; Lymphatic system; Vascular endothelial growth factor B; Cell fate determination; Vascular endothelial growth factor A; Notch proteins; In vitro; Signal transduction; Immunology; Vascular endothelial growth factor; Endocrinology; Transcription factor; Genetics; Cancer; Gene; VEGF receptors","score_opus":0.035336132152729585,"score_gpt":0.35927799344070727,"score_spread":0.3239418612879777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041249840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99710816,0.0008029929,0.0007831564,0.000034532328,0.000009389997,0.000008852148,0.00017149646,0.000021795908,0.0010596187],"genre_scores_gemma":[0.9975321,0.00039691833,0.00077718066,0.000029013947,0.0000028644806,0.000012882279,0.00021096694,0.0000071912145,0.001030773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982625,0.00004956876,0.000016603852,0.000028905375,0.000044217228,0.00003449357],"domain_scores_gemma":[0.99994624,0.00001486134,0.000014953108,0.00000889392,0.0000046516157,0.000010481797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002054758,0.000115044,0.000098242446,0.00015211075,0.000090303205,0.00024637868,0.000114966366,0.00014977127,0.0010423026],"category_scores_gemma":[0.00015204404,0.000089832116,0.00011693696,0.00009245145,0.00012779585,0.00008149912,0.00010356979,0.00020424715,0.00016858264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014688415,0.000022756489,0.0002530161,0.000013667866,0.000003886169,0.00004067758,0.000017058002,0.00008019434,0.9977665,0.00022738561,0.00004154476,0.0013864151],"study_design_scores_gemma":[0.00002968409,0.00028138864,0.003501706,0.000005976298,0.000022335895,0.00045445253,0.000023969249,0.0010287793,0.99059063,0.00009269305,0.0039638435,0.0000045862216],"about_ca_topic_score_codex":0.0006620873,"about_ca_topic_score_gemma":0.000737535,"teacher_disagreement_score":0.0010423026,"about_ca_system_score_codex":0.00034501433,"about_ca_system_score_gemma":0.00012916035,"threshold_uncertainty_score":0.0034868717},"labels":[],"label_agreement":null},{"id":"W2042355069","doi":"10.1172/jci61067","title":"Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":383,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Cancer Research UK; Wellcome Trust","keywords":"CXC chemokine receptors; Carcinogenesis; Cancer research; Inflammation; PTEN; Chemokine; Colitis; Immunology; Cancer; Mediator; Biology; Adenocarcinoma; Chemokine receptor; Medicine; Signal transduction; Internal medicine; Endocrinology; Cell biology","score_opus":0.058770457825713766,"score_gpt":0.35333346200227517,"score_spread":0.2945630041765614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042355069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99511445,0.0011597675,0.0016276398,0.00012967626,0.000040654475,0.000051346215,0.00042446627,0.00017208041,0.0012798234],"genre_scores_gemma":[0.9939335,0.0009151554,0.0016840103,0.00007749218,0.000020738227,0.000071349656,0.0006431217,0.000024604624,0.0026299516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997695,0.00004585942,0.000024812998,0.00003296597,0.000054109754,0.00007278111],"domain_scores_gemma":[0.9998573,0.000018113424,0.00003680051,0.000017840424,0.000009980294,0.000059887134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000220944,0.00042515484,0.00033886035,0.00028478281,0.00012400097,0.00027751375,0.00020329164,0.0002430875,0.0010306077],"category_scores_gemma":[0.00012812126,0.00014887452,0.00022359153,0.00011597407,0.00026706848,0.00019779551,0.00015152995,0.00081344874,0.00017729371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033383333,0.00021776443,0.00020695159,0.00004894985,0.000007958726,0.00004104766,0.00001394395,0.00013117612,0.9962315,0.00019839255,0.00012802504,0.0024404295],"study_design_scores_gemma":[0.00011311306,0.002411329,0.003906163,0.000011159302,0.000025149986,0.0003246034,0.00002611242,0.0015152317,0.988694,0.000066217544,0.00290082,0.000006031784],"about_ca_topic_score_codex":0.0005447639,"about_ca_topic_score_gemma":0.0013472192,"teacher_disagreement_score":0.0010306077,"about_ca_system_score_codex":0.00020949403,"about_ca_system_score_gemma":0.00034642548,"threshold_uncertainty_score":0.0034476519},"labels":[],"label_agreement":null},{"id":"W2043583876","doi":"10.1172/jci62888","title":"Epidermal growth factor receptor inhibits colitis-associated cancer in mice","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Crohn's and Colitis Foundation; National Institutes of Health; Vanderbilt University; Vanderbilt Digestive Diseases Research Center, Vanderbilt University Medical Center; Crohn's and Colitis Foundation of America","keywords":"Epidermal growth factor receptor; Inflammation; Cancer; Colorectal cancer; Colitis; Inflammatory bowel disease; Carcinogenesis; Epidermal growth factor; Mouse model of colorectal and intestinal cancer; Cancer research; Medicine; Immunology; Pathogenesis; Biology; Disease; Internal medicine; Receptor","score_opus":0.04615041453443422,"score_gpt":0.34919658322679936,"score_spread":0.3030461686923651,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043583876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95534104,0.007894595,0.011156898,0.0023515911,0.0006824034,0.00050317997,0.004980645,0.00239934,0.014690348],"genre_scores_gemma":[0.95071197,0.0048183794,0.010742408,0.0006562564,0.00010723835,0.00058284024,0.0040360535,0.0003806893,0.027964182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992508,0.0001713918,0.00007853971,0.00015464259,0.00016870518,0.00017597254],"domain_scores_gemma":[0.9992918,0.00011165522,0.00019121614,0.00011710309,0.000048949765,0.00023924117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059433177,0.00093402545,0.00057934166,0.0020489683,0.00042459613,0.00077781576,0.0006810147,0.001319098,0.0036930495],"category_scores_gemma":[0.00032574066,0.00066816754,0.00077582075,0.0005391856,0.0007278059,0.00047631518,0.00036361834,0.0024947193,0.0016434493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010559942,0.00084821775,0.00026735052,0.00009634408,0.00003320582,0.00014768358,0.00004383465,0.00031913587,0.99091095,0.0009872537,0.0007612982,0.004528723],"study_design_scores_gemma":[0.00074031565,0.0031626783,0.00356042,0.000068583904,0.00009089263,0.00081861665,0.00007796094,0.0045014797,0.9685507,0.00056403666,0.017834816,0.00002954529],"about_ca_topic_score_codex":0.0016203336,"about_ca_topic_score_gemma":0.0031214117,"teacher_disagreement_score":0.0036930495,"about_ca_system_score_codex":0.00092128874,"about_ca_system_score_gemma":0.0006959169,"threshold_uncertainty_score":0.012354493},"labels":[],"label_agreement":null},{"id":"W2043614750","doi":"10.1172/jci67232","title":"Potential applications for biguanides in oncology","year":2013,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"University of Cambridge","keywords":"Metformin; Medicine; Drug; Clinical trial; Pharmacology; Bioinformatics; Diabetes mellitus; Drug discovery; Insulin; Internal medicine; Biology; Endocrinology","score_opus":0.14589215009706116,"score_gpt":0.4724304834120994,"score_spread":0.32653833331503823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043614750","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022098799,0.99664885,0.0002767885,0.00035850826,0.00028411407,0.0000098151095,0.000025971625,0.000013208543,0.0021617257],"genre_scores_gemma":[0.0014435954,0.9960245,0.00049400114,0.0003388697,0.00021454808,0.000015236337,0.000051536983,0.0000031328339,0.0014146231],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99984443,0.000028447634,0.000018492648,0.000026937969,0.000063140265,0.000018549346],"domain_scores_gemma":[0.9997727,0.00010647365,0.000027436854,0.000008173157,0.00005676055,0.0000284874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060921034,0.00075282285,0.0012337292,0.0024048036,0.0003393707,0.0009317638,0.00092207955,0.0012142608,0.005461789],"category_scores_gemma":[0.0005645889,0.0002850232,0.000583032,0.0017692822,0.00050965446,0.0014978109,0.0008131907,0.0022233087,0.0032187125],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000099526515,0.000114296134,0.00019484712,0.0098081855,0.000058015445,0.0004938241,0.000075286356,0.00043212314,0.0036055814,0.008498257,0.024113856,0.9525061],"study_design_scores_gemma":[0.00002133287,0.00010209617,0.00040417808,0.001243633,0.000039580922,0.0012871583,0.000039147522,0.00008368389,0.0007186128,0.002752248,0.9932944,0.000013913531],"about_ca_topic_score_codex":0.00055261794,"about_ca_topic_score_gemma":0.001487222,"teacher_disagreement_score":0.005461789,"about_ca_system_score_codex":0.00057292625,"about_ca_system_score_gemma":0.00065806776,"threshold_uncertainty_score":0.018271506},"labels":[],"label_agreement":null},{"id":"W2043623672","doi":"10.1172/jci70230","title":"Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Eye Institute; Manpei Suzuki Diabetes Foundation; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Japan Society for the Promotion of Science; Lowy Medical Research Institute","keywords":"Angiogenesis; Neovascularization; Sprouting angiogenesis; Cancer research; microRNA; Vascular endothelial growth factor; Immunology; Vascular endothelial growth factor A; Macular degeneration; Biology; Cell biology; Medicine; VEGF receptors; Ophthalmology; Biochemistry","score_opus":0.033054122521371236,"score_gpt":0.3140908320643114,"score_spread":0.28103670954294013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043623672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937133,0.0013480604,0.0023872212,0.00017253059,0.000098132616,0.000037415943,0.00020058229,0.00028328644,0.0017595107],"genre_scores_gemma":[0.99399674,0.0010881674,0.0019861986,0.000046813217,0.000019897436,0.00004088128,0.00027475136,0.000036086585,0.002510418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997954,0.000036877063,0.000023929611,0.00003748828,0.00005305792,0.000053266802],"domain_scores_gemma":[0.99988425,0.000022803551,0.000034294466,0.000015667973,0.00001222324,0.000030689363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015510492,0.00036512068,0.0004020404,0.00028677643,0.00016880769,0.00033085156,0.00027053643,0.00024316933,0.0011666236],"category_scores_gemma":[0.00013863614,0.00017527498,0.00027686468,0.00013496175,0.00032297985,0.00019108463,0.00012217576,0.0008762125,0.0002929399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026364834,0.0001358448,0.00006943066,0.000035953948,0.0000071646136,0.000025093392,0.000010492834,0.000066891334,0.99653184,0.00021005291,0.00010982085,0.0025338219],"study_design_scores_gemma":[0.00003473015,0.0006362272,0.00052276487,0.0000031225227,0.000011823428,0.000088655084,0.000009102615,0.0008245182,0.99630004,0.000037079088,0.0015288907,0.0000030209335],"about_ca_topic_score_codex":0.00065242936,"about_ca_topic_score_gemma":0.0012850871,"teacher_disagreement_score":0.0011666236,"about_ca_system_score_codex":0.00029489415,"about_ca_system_score_gemma":0.0003887057,"threshold_uncertainty_score":0.0039027333},"labels":[],"label_agreement":null},{"id":"W2043714441","doi":"10.1172/jci60560","title":"Mutations in the ER-shaping protein reticulon 2 cause the axon-degenerative disorder hereditary spastic paraplegia type 12","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hereditary Neurological Disorders","field":"Neuroscience","cited_by":170,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Cambridge Institute for Medical Research, University of Cambridge; National Institutes of Health; Canada Excellence Research Chairs, Government of Canada; University of Miami; E-Rare; Spastic Paraplegia Foundation; Leonard M. Miller School of Medicine; Wellcome Trust; European Commission","keywords":"Hereditary spastic paraplegia; Frameshift mutation; Biology; Genetics; Mutation; Mutant protein; Gene; Cell biology; Phenotype","score_opus":0.23684033973893093,"score_gpt":0.39066549867703915,"score_spread":0.15382515893810822,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043714441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99555737,0.000717828,0.0011402973,0.00013117738,0.000035923378,0.000051904008,0.0004506268,0.00017702034,0.0017378024],"genre_scores_gemma":[0.9959247,0.00037016638,0.0013927736,0.00011917018,0.000028574968,0.000020984537,0.0004888335,0.00003113333,0.0016235353],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980253,0.000037134003,0.000018064338,0.000059097405,0.000055984325,0.000027183496],"domain_scores_gemma":[0.9998418,0.000025813688,0.000058987,0.000009023943,0.000011297715,0.000052994237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013726155,0.0018403139,0.00038731453,0.00063875143,0.0002870831,0.00017866406,0.0003226816,0.0006646202,0.0015612801],"category_scores_gemma":[0.00039296862,0.00031423778,0.0002916427,0.00035794682,0.00037238502,0.000113697024,0.00046698918,0.0003628162,0.0005672351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014365034,0.00024831574,0.04224797,0.00036764823,0.00040112663,0.091543764,0.00048443605,0.0008766606,0.83333373,0.0006661698,0.0026495007,0.025744198],"study_design_scores_gemma":[0.000599602,0.0017875732,0.48901173,0.00019499542,0.0005833445,0.33980814,0.00040179968,0.0047162287,0.14267854,0.0008325122,0.019284956,0.00010057818],"about_ca_topic_score_codex":0.0009656584,"about_ca_topic_score_gemma":0.0017122215,"teacher_disagreement_score":0.0018403139,"about_ca_system_score_codex":0.00042083228,"about_ca_system_score_gemma":0.00020949722,"threshold_uncertainty_score":0.005223036},"labels":[],"label_agreement":null},{"id":"W2044862076","doi":"10.1172/jci17416","title":"The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":202,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; National Institutes of Health","keywords":"Calcium-sensing receptor; Endocrinology; Internal medicine; Parathyroid hormone; Calcium; Null allele; Parathyroid gland; Calcium metabolism; Hyperparathyroidism; Receptor; Parathyroid chief cell; Homeostasis; Biology; Phenotype; Medicine; Gene; Genetics","score_opus":0.1276936477273825,"score_gpt":0.40151334465723043,"score_spread":0.2738196969298479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044862076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96721387,0.007817549,0.011210393,0.0006243622,0.00023163029,0.00008084656,0.0018815118,0.00081392314,0.010125868],"genre_scores_gemma":[0.98557776,0.0021907918,0.003622532,0.00014989116,0.000046850237,0.00006710077,0.0010821046,0.00010450994,0.0071584713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999469,0.000046414105,0.000049981325,0.0001101063,0.00021830926,0.00010634157],"domain_scores_gemma":[0.9994791,0.000059963844,0.00014734043,0.00006946626,0.000074680676,0.00016940432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001855388,0.0003401197,0.00036928497,0.0003055641,0.00021933872,0.00064605335,0.00056780525,0.00050501927,0.002110989],"category_scores_gemma":[0.00042030727,0.0002934257,0.00029137838,0.0001517655,0.0004192089,0.00033527726,0.0004918613,0.0006920561,0.0015270014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000739016,0.000011623442,0.0002753332,0.000032181626,0.0000043700625,0.00017054076,0.000011622179,0.000041445,0.9973327,0.0003874045,0.00011092262,0.0015478081],"study_design_scores_gemma":[0.000100737154,0.00034754467,0.035015594,0.000031529697,0.00005969173,0.00370735,0.00010549333,0.0020305237,0.9271904,0.00050035457,0.030869294,0.0000416021],"about_ca_topic_score_codex":0.0007882415,"about_ca_topic_score_gemma":0.00081155886,"teacher_disagreement_score":0.002110989,"about_ca_system_score_codex":0.0003279158,"about_ca_system_score_gemma":0.00040749018,"threshold_uncertainty_score":0.0070619583},"labels":[],"label_agreement":null},{"id":"W2045610340","doi":"10.1172/jci39027","title":"Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Queen's University","funders":"Canadian Institutes of Health Research; Queen's University; Heart and Stroke Foundation of Canada","keywords":"hERG; Internalization; Chemistry; Potassium channel; Extracellular; Ion channel; Cell biology; Biophysics; Pharmacology; Biochemistry; Cell; Biology; Receptor","score_opus":0.033968906032684695,"score_gpt":0.3253285174191095,"score_spread":0.2913596113864248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045610340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942473,0.0020814168,0.0021508113,0.000082948085,0.000013300468,0.000010510414,0.00019381204,0.000036861595,0.0011830302],"genre_scores_gemma":[0.9967392,0.0007984428,0.001324994,0.000030809148,0.0000061063715,0.000019955512,0.0003631131,0.000020985019,0.00069645373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99964726,0.00008082675,0.00005218299,0.00008765632,0.00007425445,0.000057772646],"domain_scores_gemma":[0.9997869,0.000081549646,0.00004453466,0.00005108213,0.000020656888,0.0000152405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032570682,0.0001456752,0.00032430785,0.00019423777,0.00013584565,0.0004462492,0.00017843099,0.00029753832,0.00094120426],"category_scores_gemma":[0.00045606977,0.00020423351,0.00023071031,0.00022311366,0.00033208178,0.00030903495,0.00020237105,0.00031527033,0.0004578319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016509429,0.0000133361045,0.0008163833,0.000024035477,0.0000059116273,0.00005398254,0.00006317974,0.00006221903,0.9980804,0.00008893972,0.000027191438,0.0005992383],"study_design_scores_gemma":[0.00003157351,0.0003255686,0.018866237,0.0000070577653,0.000036265137,0.00088348624,0.00013512775,0.0017939289,0.9760617,0.00011139629,0.0017375115,0.00001021326],"about_ca_topic_score_codex":0.00088690117,"about_ca_topic_score_gemma":0.0006501194,"teacher_disagreement_score":0.00094120426,"about_ca_system_score_codex":0.00032656963,"about_ca_system_score_gemma":0.000102629805,"threshold_uncertainty_score":0.003148675},"labels":[],"label_agreement":null},{"id":"W2045666417","doi":"10.1172/jci22954","title":"Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; National Research Council Canada; University of Ottawa","funders":"Canadian Institutes of Health Research; Alzheimer Society; National Institutes of Health; Sidaction; National Institute of Allergy and Infectious Diseases; Association pour la Recherche sur le Cancer; Styrelsen för Internationellt Utvecklingssamarbete; Wellcome Trust; Heart and Stroke Foundation of Canada","keywords":"Adenine nucleotide translocator; Apoptosis; Ritonavir; Nelfinavir; In vivo; Protease; Biology; Protease inhibitor (pharmacology); Lopinavir; Pharmacology; Mitochondrial permeability transition pore; Programmed cell death; Cell biology; Biochemistry; Virology; Enzyme; Virus; Viral load","score_opus":0.03840242906712337,"score_gpt":0.3086819531659627,"score_spread":0.2702795240988393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045666417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99669856,0.0014475671,0.0009318258,0.00007318098,0.000018803143,0.000017587605,0.000055892222,0.000038511735,0.0007180726],"genre_scores_gemma":[0.9969144,0.0011221416,0.0010180833,0.000026682304,0.000014194954,0.000018513376,0.00014031847,0.00000476916,0.00074102636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998704,0.00003535251,0.000010348429,0.000009838575,0.000027319582,0.000046682722],"domain_scores_gemma":[0.9998714,0.000030027588,0.000037177557,0.000018233855,0.000011300754,0.000031816824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002211168,0.00028160066,0.00030628426,0.0001937936,0.000118986936,0.0002622363,0.00022469534,0.00022065602,0.00097512087],"category_scores_gemma":[0.00019986535,0.00010583894,0.00014844319,0.000099037636,0.00021235945,0.00033691715,0.00008940823,0.0006890242,0.00016635035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012840884,0.0004041935,0.00034145598,0.000054676242,0.000018851093,0.000059378977,0.000020306717,0.00017721372,0.98923326,0.00020577021,0.000069660804,0.008131171],"study_design_scores_gemma":[0.00015952688,0.007757896,0.0049390555,0.000011210549,0.00003743623,0.000309479,0.000028200682,0.0013049151,0.9842163,0.0001366918,0.0010936297,0.000005638905],"about_ca_topic_score_codex":0.00023349933,"about_ca_topic_score_gemma":0.00050971494,"teacher_disagreement_score":0.00097512087,"about_ca_system_score_codex":0.00014752585,"about_ca_system_score_gemma":0.00017631995,"threshold_uncertainty_score":0.0032621622},"labels":[],"label_agreement":null},{"id":"W2046287467","doi":"10.1172/jci66735","title":"Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Ottawa; University of Toronto","funders":"Exploratory Research for Advanced Technology; Council for Science and Technology Policy; Johns Hopkins University; University of Texas Southwestern Medical Center; University of California, San Francisco; Macula Vision Research Foundation; Japan Science and Technology Agency; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs; Japan Society for the Promotion of Science; Howard Hughes Medical Institute","keywords":"Knockout mouse; Biology; Hypothermia; Endocrinology; Internal medicine; Conditional gene knockout; Gene knockout; Homeothermy; Phenotype; Gene targeting; Lung; Immunology; Thermoregulation; Receptor; Medicine; Physiology; Gene; Genetics","score_opus":0.10618561738289656,"score_gpt":0.35082809304247176,"score_spread":0.2446424756595752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046287467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928745,0.00078019936,0.004037519,0.000096278025,0.000032073105,0.000044108387,0.0011010709,0.0002446372,0.00078956666],"genre_scores_gemma":[0.98636985,0.0014751742,0.005028974,0.00012001067,0.00002242613,0.00016637474,0.00161888,0.00014664131,0.0050516096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997874,0.000032944587,0.00003465567,0.00006376701,0.000045145323,0.00003602166],"domain_scores_gemma":[0.99972016,0.000038445425,0.00011670167,0.000030231698,0.000013542402,0.000080917715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023754897,0.00073246117,0.00036069646,0.00084394886,0.0002087465,0.00027099336,0.00029766373,0.0005427441,0.0019832766],"category_scores_gemma":[0.0001873135,0.00043260056,0.00041005717,0.00025164487,0.0004040974,0.0002632702,0.00038369978,0.0008100051,0.00052059663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021283953,0.0000678555,0.0004171126,0.000030354557,0.000015254936,0.0003049425,0.000026750837,0.000110442015,0.9976446,0.00012313297,0.00005215121,0.000994475],"study_design_scores_gemma":[0.00036188104,0.0015618232,0.035697147,0.000073115254,0.00015513938,0.0052421675,0.00013093033,0.002888183,0.9485943,0.00039833647,0.004859551,0.00003748956],"about_ca_topic_score_codex":0.0005644761,"about_ca_topic_score_gemma":0.0010471056,"teacher_disagreement_score":0.0019832766,"about_ca_system_score_codex":0.0002975284,"about_ca_system_score_gemma":0.00020998478,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W2046455986","doi":"10.1172/jci36136","title":"VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; McMaster University Medical Centre; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; McMaster University; GlaxoSmithKline","keywords":"Lung; Apoptosis; Pulmonary hypertension; Pulmonary fibrosis; Fibrosis; Medicine; VEGF receptors; Vascular endothelial growth factor A; Cancer research; Pharmacology; Internal medicine; Vascular endothelial growth factor; Cardiology; Biology; Biochemistry","score_opus":0.09236363496534912,"score_gpt":0.39093645252231524,"score_spread":0.29857281755696613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046455986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948565,0.0017941276,0.0019172325,0.00029079439,0.00005481871,0.000049512964,0.00007784796,0.00020839395,0.00075079873],"genre_scores_gemma":[0.99460584,0.0013403507,0.002133761,0.00010556157,0.000041173214,0.00006158462,0.0001421916,0.00001904385,0.0015504564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979013,0.000059363854,0.000019939736,0.000024499692,0.000041014708,0.000065076805],"domain_scores_gemma":[0.9997112,0.000033549542,0.00012798478,0.00002540435,0.000028291666,0.000073574236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035154365,0.00051742804,0.00041677765,0.0005913847,0.00017840597,0.00022444953,0.00023322146,0.0003846612,0.0011352958],"category_scores_gemma":[0.00032569128,0.00021255856,0.00029127422,0.00013660699,0.00044734785,0.0003086934,0.00016378236,0.0008788024,0.00019468408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026529997,0.0014812548,0.0009291108,0.00012971932,0.000023486771,0.000287908,0.000044391134,0.00029431118,0.9802036,0.00034593852,0.00018461309,0.013422731],"study_design_scores_gemma":[0.0009628819,0.023114618,0.011323788,0.000048900103,0.00009129053,0.0011927158,0.00009202154,0.003341907,0.95696133,0.00044904748,0.002402636,0.00001878379],"about_ca_topic_score_codex":0.00071097794,"about_ca_topic_score_gemma":0.0008766622,"teacher_disagreement_score":0.0011352958,"about_ca_system_score_codex":0.00029356507,"about_ca_system_score_gemma":0.0003065004,"threshold_uncertainty_score":0.0037979484},"labels":[],"label_agreement":null},{"id":"W2046919826","doi":"10.1172/jci43350","title":"The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Occupational Cancer Research Centre; McGill University Health Centre","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; McGill University","keywords":"Spermiogenesis; Messenger RNA; Translation (biology); Biology; Cell biology; Poly(A)-binding protein; Molecular biology; Gene; Genetics; Nucleus","score_opus":0.0956411812667049,"score_gpt":0.3855982795164424,"score_spread":0.2899570982497375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046919826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9486498,0.009481346,0.027168255,0.0008641834,0.0004255601,0.00020845875,0.005975508,0.0019252,0.0053016674],"genre_scores_gemma":[0.9650388,0.0048749363,0.010515989,0.00042063993,0.00012888752,0.00060012593,0.0032174273,0.00081040425,0.014392801],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947995,0.00005814034,0.000055795834,0.00019377064,0.00012687856,0.00008546574],"domain_scores_gemma":[0.9992459,0.00007073655,0.0002795564,0.00006483169,0.000043081498,0.00029587816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047348836,0.0008841437,0.0006759546,0.001220426,0.0005096435,0.0009854115,0.0009171858,0.0010553342,0.004261299],"category_scores_gemma":[0.00031827766,0.0009923517,0.0007108092,0.0005103973,0.000884638,0.00062878104,0.00074027135,0.0023300324,0.0020193895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003685715,0.000058496556,0.00035246377,0.000084709856,0.000016639398,0.00015372671,0.000031341304,0.00012803449,0.9965892,0.00044792285,0.00020851356,0.001560388],"study_design_scores_gemma":[0.00047658227,0.00062592886,0.01354,0.00010911548,0.00015203285,0.0016418897,0.00012368755,0.0040762587,0.9525559,0.0007224005,0.025926404,0.00004976351],"about_ca_topic_score_codex":0.00066248904,"about_ca_topic_score_gemma":0.0010878666,"teacher_disagreement_score":0.004261299,"about_ca_system_score_codex":0.00063955854,"about_ca_system_score_gemma":0.00046871553,"threshold_uncertainty_score":0.0142554045},"labels":[],"label_agreement":null},{"id":"W2047301656","doi":"10.1172/jci37901","title":"Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":290,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Ontario Genomics; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Mutation; Immunology; Biology; Kinase; Medicine; Cancer research; Virology; Genetics; Gene","score_opus":0.07895158821462415,"score_gpt":0.3440478635269209,"score_spread":0.26509627531229674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047301656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977397,0.00028506477,0.00071310496,0.00009372081,0.0000248169,0.000016285474,0.00020357591,0.00006441294,0.00085935707],"genre_scores_gemma":[0.9981805,0.00025661747,0.00057359604,0.000068165085,0.000015716967,0.00000978025,0.00014882506,0.000026712956,0.000720179],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.9998215,0.000015019082,0.000023259858,0.00006474642,0.000032816828,0.00004272471],"domain_scores_gemma":[0.99980694,0.00003444862,0.00007633852,0.000013674805,0.000009642627,0.00005899203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008972091,0.0010109517,0.0005511196,0.0005434518,0.0005466137,0.00038720918,0.00030436568,0.0007634971,0.0018017697],"category_scores_gemma":[0.00036447347,0.00031315934,0.00041659534,0.00026968066,0.00049995683,0.0002752568,0.00047996105,0.00062637386,0.0006205935],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071639696,0.00027629704,0.11195572,0.0001967042,0.0001351156,0.4553267,0.0012828351,0.00054006773,0.4119104,0.0011200702,0.0009469729,0.015592559],"study_design_scores_gemma":[0.00009549283,0.00067221985,0.11722664,0.000041692034,0.0000974979,0.82902116,0.0005050718,0.0007341886,0.047519695,0.00033189188,0.0037072646,0.0000472062],"about_ca_topic_score_codex":0.0005598555,"about_ca_topic_score_gemma":0.0006374728,"teacher_disagreement_score":0.0018017697,"about_ca_system_score_codex":0.0001977282,"about_ca_system_score_gemma":0.00020056003,"threshold_uncertainty_score":0.00602746},"labels":[],"label_agreement":null},{"id":"W2047893094","doi":"10.1172/jci65642","title":"Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":370,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Filaggrin; Aryl hydrocarbon receptor; Atopic dermatitis; Immunology; Cell biology; Cancer research; Chemistry; Biology; Transcription factor; Biochemistry","score_opus":0.05207025210957617,"score_gpt":0.3577454110220966,"score_spread":0.30567515891252045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047893094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99581003,0.00178003,0.0010157212,0.00008747362,0.000039439074,0.000038606457,0.00010705959,0.00006443666,0.0010572446],"genre_scores_gemma":[0.9972064,0.0007285471,0.00046235207,0.0000436702,0.000008379234,0.000017648259,0.00009742565,0.000004688617,0.0014308896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999923,0.000021612806,0.0000069041794,0.000008766098,0.000020116688,0.00001953577],"domain_scores_gemma":[0.9999616,0.0000068975096,0.000007391427,0.000005948861,0.0000057292295,0.000012365486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012350817,0.00021811933,0.0001777787,0.00023938996,0.00013385773,0.0001546051,0.00010870984,0.00019335415,0.0016198548],"category_scores_gemma":[0.00006695093,0.0000985768,0.00022658965,0.00010528631,0.0001558453,0.00015789962,0.00015488929,0.00043623228,0.00024732883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003100725,0.00015873455,0.00014966511,0.00004314089,0.000005023244,0.00007728966,0.00001325654,0.000036878868,0.9971512,0.00008364484,0.00004886327,0.001922199],"study_design_scores_gemma":[0.00008718133,0.0015727924,0.009522154,0.000008299268,0.000025492798,0.00042865935,0.000052954452,0.0008667758,0.98564875,0.00015195171,0.0016303781,0.0000046541845],"about_ca_topic_score_codex":0.00034068522,"about_ca_topic_score_gemma":0.00057468785,"teacher_disagreement_score":0.0016198548,"about_ca_system_score_codex":0.0001491698,"about_ca_system_score_gemma":0.00012802052,"threshold_uncertainty_score":0.0054188967},"labels":[],"label_agreement":null},{"id":"W2047909722","doi":"10.1172/jci38814","title":"Putting a stop to organ trafficking and tourism","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Organ Donation and Transplantation","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Tourism; Poison control; Medicine; Criminology; Medical emergency; Political science; Psychology; Law","score_opus":0.06965413402559062,"score_gpt":0.39211037293692985,"score_spread":0.32245623891133923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047909722","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018911825,0.005304041,0.00084253756,0.9491611,0.026703775,0.000021074136,0.00003702872,0.000085832755,0.015953414],"genre_scores_gemma":[0.046190966,0.0059829075,0.0019360267,0.9049335,0.009144909,0.00007641101,0.00014026325,0.00016055118,0.031434517],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98724407,0.0056392755,0.00074448023,0.00071667996,0.0026053449,0.003050051],"domain_scores_gemma":[0.9853999,0.0037090431,0.0016363653,0.00069963624,0.0029149842,0.005640106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.010557147,0.00094371097,0.00079710776,0.0009160309,0.014611413,0.014003514,0.002193379,0.023561046,0.018883565],"category_scores_gemma":[0.019187422,0.00065272785,0.0009548185,0.0005944456,0.01253791,0.011745681,0.016076349,0.029878866,0.005126187],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005148774,0.00009359894,0.0011517055,0.0003542295,0.000025972753,0.00040596773,0.005971302,0.000083437546,0.00059732154,0.03531765,0.9218704,0.03407696],"study_design_scores_gemma":[0.000013862578,0.000049141294,0.00091426336,0.00083474856,0.00001107835,0.0003685184,0.0122780865,0.000055211905,0.00035731064,0.009152417,0.9759243,0.000040949206],"about_ca_topic_score_codex":0.008265783,"about_ca_topic_score_gemma":0.021635273,"teacher_disagreement_score":0.023561046,"about_ca_system_score_codex":0.0051414836,"about_ca_system_score_gemma":0.019449176,"threshold_uncertainty_score":0.063171804},"labels":[],"label_agreement":null},{"id":"W2047975415","doi":"10.1172/jci8185","title":"IL-1α, IL-1β, and IFN-γ mark β cells for Fas-dependent destruction by diabetogenic CD4+ T lymphocytes","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Medical Research Council Canada; Medical Research Council; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canadian Diabetes Association","keywords":"Insulitis; NOD mice; Biology; Cytokine; Cytotoxic T cell; Interleukin 21; T cell; Immunology; Nod; Immune system; Cancer research; Autoimmunity; In vitro; Endocrinology; Diabetes mellitus","score_opus":0.01689404831171086,"score_gpt":0.2885047615161923,"score_spread":0.27161071320448144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047975415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815859,0.006058183,0.008625936,0.00009900687,0.00009162955,0.000039828923,0.00023402598,0.00016469866,0.003100815],"genre_scores_gemma":[0.9862119,0.0029753607,0.007634395,0.000093075876,0.00004095567,0.000046703044,0.0003714814,0.0000315223,0.0025947178],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984527,0.000023580698,0.000016739936,0.000040442534,0.000031577038,0.00004238187],"domain_scores_gemma":[0.99988186,0.000013043073,0.000057165835,0.000018363078,0.000009809327,0.000019744495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012592116,0.00054281065,0.0002624039,0.00033645876,0.00013836038,0.00044369235,0.00021792829,0.0003736426,0.0012478919],"category_scores_gemma":[0.000118313415,0.0002079977,0.00027292166,0.00015993862,0.0003090179,0.0003502943,0.0002514367,0.0007518231,0.0007198426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011035147,0.000009647674,0.0004554124,0.00004186868,0.0000055871933,0.0000563323,0.000023606248,0.00004575069,0.9976113,0.00013607225,0.000014079167,0.0014900413],"study_design_scores_gemma":[0.00003334823,0.00031179553,0.0030764665,0.000018085975,0.00002821539,0.0008030729,0.000040403,0.0002602393,0.99173003,0.00017853879,0.003515478,0.000004280305],"about_ca_topic_score_codex":0.000170537,"about_ca_topic_score_gemma":0.00018328146,"teacher_disagreement_score":0.0012478919,"about_ca_system_score_codex":0.00030776096,"about_ca_system_score_gemma":0.00016864423,"threshold_uncertainty_score":0.00417459},"labels":[],"label_agreement":null},{"id":"W2048653810","doi":"10.1172/jci31809","title":"New molecularly targeted therapies for lung cancer","year":2007,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; Gillson Longenbaugh Foundation","keywords":"Lung cancer; Medicine; Disease; Cancer; Targeted therapy; Bioinformatics; Intensive care medicine; Oncology; Pathology; Internal medicine; Biology","score_opus":0.18508919977471613,"score_gpt":0.547475026098917,"score_spread":0.3623858263242008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048653810","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023332724,0.9964036,0.00039724307,0.00052246184,0.00033923204,0.000013888741,0.000014252898,0.000016738999,0.002059363],"genre_scores_gemma":[0.00088229636,0.9963915,0.0005894953,0.00049287017,0.0002771544,0.000017291184,0.000028852315,0.000002002822,0.0013185893],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997546,0.000044963468,0.000022291246,0.000032142434,0.00012416896,0.000021784423],"domain_scores_gemma":[0.99981934,0.00008048719,0.000023758115,0.000008137961,0.00004670291,0.000021597773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007484715,0.00089444255,0.0012456742,0.00229514,0.00040662405,0.0007494625,0.0009505783,0.0013949549,0.004090736],"category_scores_gemma":[0.0005066603,0.0002411116,0.00062245916,0.0014037363,0.00061444705,0.0013109248,0.000530898,0.0028477951,0.003282579],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007841663,0.00022425439,0.00014452396,0.0049176794,0.000075217744,0.0004321452,0.000055619133,0.000492213,0.006657044,0.0054112147,0.038125355,0.9433863],"study_design_scores_gemma":[0.00005906984,0.00018199165,0.0006449181,0.0011874161,0.000060660677,0.002582636,0.00003427946,0.00011934473,0.0013604715,0.0025118224,0.9912397,0.000017565264],"about_ca_topic_score_codex":0.0007248645,"about_ca_topic_score_gemma":0.0020345973,"teacher_disagreement_score":0.004090736,"about_ca_system_score_codex":0.00065324194,"about_ca_system_score_gemma":0.0006811344,"threshold_uncertainty_score":0.013684869},"labels":[],"label_agreement":null},{"id":"W2049422105","doi":"10.1172/jci64180","title":"Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; BC Cancer Agency; Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Human Genome Research Institute; Ontario Ministry of Research and Innovation; Terry Fox Foundation; Stem Cell Network; Ontario Ministry of Health and Long-Term Care; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; International Myeloma Foundation","keywords":"Myeloid leukemia; Lysosome; Biology; Progenitor cell; Leukemia; Cancer research; Cell biology; Stem cell; Haematopoiesis; Cathepsin; Vacuole; LAMP1; Immunology; Biochemistry","score_opus":0.05401678840932425,"score_gpt":0.3679316941701927,"score_spread":0.31391490576086845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049422105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98599696,0.004840519,0.004809479,0.00017755695,0.000020164951,0.000074876734,0.00046328615,0.00011631806,0.003500795],"genre_scores_gemma":[0.99247736,0.0021000856,0.0023646746,0.000097279,0.0000084165995,0.00003044637,0.0005979361,0.000024617642,0.0022991137],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997826,0.00004507017,0.000018255205,0.000047751313,0.00006914943,0.000037187092],"domain_scores_gemma":[0.99990416,0.00002590502,0.00002231762,0.000016125554,0.000012142398,0.0000193567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018693239,0.00030395188,0.00044019168,0.000273194,0.00016564234,0.0005783513,0.000213348,0.0002992889,0.0012028419],"category_scores_gemma":[0.00021351449,0.00013165512,0.00018970459,0.00019312072,0.00022102555,0.00021720536,0.00030269622,0.0004511932,0.0003671684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012730873,0.000040318173,0.0005898787,0.0000497268,0.0000063427424,0.00008536888,0.000015664102,0.00010968148,0.9958293,0.00021728515,0.00008481884,0.0028444873],"study_design_scores_gemma":[0.000024175748,0.00040447744,0.0041351547,0.0000085977645,0.000016103553,0.00064868014,0.000031146956,0.00062453863,0.98929346,0.00012631225,0.0046837986,0.0000035431162],"about_ca_topic_score_codex":0.000452085,"about_ca_topic_score_gemma":0.0010318431,"teacher_disagreement_score":0.0012028419,"about_ca_system_score_codex":0.00034971404,"about_ca_system_score_gemma":0.00024833993,"threshold_uncertainty_score":0.0040239096},"labels":[],"label_agreement":null},{"id":"W2049606715","doi":"10.1172/jci59334","title":"Alkylpurine–DNA–N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":172,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; University of Toronto; Cancer Research UK; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Temozolomide; Methyltransferase; Cancer research; O-6-methylguanine-DNA methyltransferase; DNA repair; DNA methylation; Methylation; Base excision repair; DNA damage; DNA methyltransferase; DNA glycosylase; Biology; Glioma; Chemotherapy; Gene silencing; Medicine; DNA; Gene expression; Gene; Genetics","score_opus":0.07493974418375068,"score_gpt":0.32115138295117873,"score_spread":0.24621163876742805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049606715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976399,0.00082306337,0.0006415317,0.00006474984,0.000026308417,0.000015184178,0.00039590907,0.00005615278,0.00033725746],"genre_scores_gemma":[0.9965413,0.0005871678,0.0005575222,0.00002541324,0.000005531666,0.000026332431,0.0010515304,0.000009197379,0.0011957644],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99987924,0.000017501634,0.00001100838,0.000021876709,0.00003939814,0.00003098414],"domain_scores_gemma":[0.9999186,0.000007541243,0.000019656332,0.000010030142,0.000010874914,0.000033277996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017437566,0.00030596904,0.00039938683,0.00026785006,0.00010717354,0.00022725972,0.00014034689,0.00017651627,0.00080649473],"category_scores_gemma":[0.00007119075,0.00014402649,0.00022137396,0.00022588429,0.00012751321,0.00015113615,0.00013930957,0.0007355465,0.00016476023],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038858035,0.00017025172,0.0014078972,0.00003698894,0.000028227863,0.000057229794,0.00003140615,0.00012464127,0.9953376,0.0000719361,0.00019934685,0.00214592],"study_design_scores_gemma":[0.00007306103,0.0050405073,0.06380989,0.000014582361,0.00010563256,0.0007749044,0.00012028635,0.006479724,0.91947234,0.00009714989,0.0039975108,0.000014367774],"about_ca_topic_score_codex":0.0026875685,"about_ca_topic_score_gemma":0.003687788,"teacher_disagreement_score":0.0026875685,"about_ca_system_score_codex":0.00034707953,"about_ca_system_score_gemma":0.0002550176,"threshold_uncertainty_score":0.0053438544},"labels":[],"label_agreement":null},{"id":"W2050928426","doi":"10.1172/jci76238","title":"Follicular helper T cell signature in type 1 diabetes","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; University of Birmingham; Diabetes UK; University College London; Wellcome Trust","keywords":"BCL6; Biology; Immunology; CXCR5; Cellular differentiation; Population; T cell; Interleukin 21; Cell; B cell; Genetics; Immune system; Medicine; Antibody; Germinal center; Gene","score_opus":0.016895670279940014,"score_gpt":0.2930540634438294,"score_spread":0.2761583931638894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050928426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99427575,0.0018072694,0.00086496724,0.000063626234,0.000021495314,0.000023337037,0.00031985148,0.000068152345,0.0025557168],"genre_scores_gemma":[0.99630874,0.0008480543,0.00086753716,0.000079657635,0.000041568695,0.00001821985,0.0003359399,0.00000936836,0.0014908635],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999379,0.000010986184,0.000003943001,0.00002145377,0.000012222101,0.000013432547],"domain_scores_gemma":[0.9999405,0.000010499045,0.000016244283,0.000005298519,0.000009041909,0.000018357643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010754373,0.00018076765,0.0001371119,0.0004584988,0.000114659815,0.00015395047,0.00008946546,0.00017529153,0.0018684444],"category_scores_gemma":[0.0001201414,0.000054172127,0.000074917065,0.00018186182,0.00013475984,0.00007785945,0.00010945127,0.00021968092,0.000288302],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006673112,0.000065773966,0.036808617,0.000095033996,0.00000980412,0.0012480997,0.00012067747,0.000058887024,0.9457607,0.00023973368,0.0003279156,0.014597473],"study_design_scores_gemma":[0.00012046947,0.0015637581,0.73746735,0.00007567138,0.00008095245,0.02314208,0.00040314006,0.0010464168,0.2121729,0.0012335144,0.02266624,0.000027407585],"about_ca_topic_score_codex":0.00023962723,"about_ca_topic_score_gemma":0.00027750529,"teacher_disagreement_score":0.0018684444,"about_ca_system_score_codex":0.00011187733,"about_ca_system_score_gemma":0.00006372411,"threshold_uncertainty_score":0.00625062},"labels":[],"label_agreement":null},{"id":"W2050988768","doi":"10.1172/jci57734","title":"Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Canadian Institutes of Health Research; University of Virginia; American Heart Association","keywords":"Pulmonary hypertension; Calpain; Pulmonary artery; Medicine; Vascular smooth muscle; Internal medicine; Vascular remodelling in the embryo; Endocrinology; Pharmacology; Cancer research; Biology; Smooth muscle; Biochemistry","score_opus":0.06794584645856784,"score_gpt":0.28705923505474523,"score_spread":0.2191133885961774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050988768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9639491,0.022210252,0.008223387,0.0013516077,0.0002627827,0.00017134058,0.0005202448,0.00029655802,0.0030147145],"genre_scores_gemma":[0.98215693,0.009709259,0.0037160465,0.0002616583,0.000097772696,0.00017857472,0.00055851636,0.000026545875,0.003294741],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998235,0.00003771788,0.000016321417,0.00003334307,0.000039458697,0.000049673872],"domain_scores_gemma":[0.9998419,0.000011456089,0.00005937146,0.000013121074,0.000016431246,0.000057722988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027398302,0.00056953105,0.00035584852,0.00038668758,0.00020117346,0.0003322813,0.00032408684,0.00047473705,0.0012894744],"category_scores_gemma":[0.00023411997,0.00014483959,0.00028836442,0.00019042258,0.00042341102,0.00030188178,0.00018564638,0.0013163151,0.00022336376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014664232,0.0004135347,0.0005426079,0.00021462001,0.000026610975,0.00021393463,0.000025918636,0.00006186134,0.9884897,0.00024255521,0.00030679195,0.00799555],"study_design_scores_gemma":[0.0006203418,0.0048105656,0.026646892,0.00007180629,0.00015333509,0.0015982538,0.000104069215,0.0018514837,0.95707726,0.00036606696,0.0066872723,0.000012631099],"about_ca_topic_score_codex":0.00038129953,"about_ca_topic_score_gemma":0.0008845435,"teacher_disagreement_score":0.0012894744,"about_ca_system_score_codex":0.00029363867,"about_ca_system_score_gemma":0.00030966345,"threshold_uncertainty_score":0.004313767},"labels":[],"label_agreement":null},{"id":"W2052117565","doi":"10.1172/jci10727","title":"Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":318,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; Royal Victoria Hospital; Xenon Pharmaceuticals (Canada); McGill University Health Centre; Royal Victoria Regional Health Centre; University of British Columbia","funders":"Medical Research Council; Promotion and Mutual Aid Corporation for Private Schools of Japan; BC Children's Hospital; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Tangier disease; ABCA1; Cholesterol; Heterozygote advantage; Internal medicine; Endocrinology; Efflux; Compound heterozygosity; Familial hypercholesterolemia; Biology; ATP Binding Cassette Transporter 1; Coronary artery disease; Residual risk; Medicine; Genetics; Mutation; Genotype; Gene; Transporter","score_opus":0.07301918080886562,"score_gpt":0.3619216805767536,"score_spread":0.288902499767888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052117565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992925,0.00023658063,0.000102231104,0.000036080102,0.000008567553,0.0000033968531,0.000029586303,0.000006385046,0.000284591],"genre_scores_gemma":[0.99943346,0.0001063028,0.00012263098,0.000029911624,0.000015959957,0.000003399831,0.00004368916,0.000004495068,0.00024007235],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9996797,0.00008369986,0.000041361793,0.00007555352,0.000050585975,0.00006923891],"domain_scores_gemma":[0.9993943,0.00020775755,0.00017662026,0.00003613833,0.00004161373,0.0001436003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004474617,0.00063870486,0.00043244945,0.0013338195,0.00041194586,0.00038314564,0.00016911315,0.00072827906,0.0023202323],"category_scores_gemma":[0.002556215,0.00029908292,0.00025128573,0.0003722512,0.00044850065,0.00030743724,0.0002826691,0.000308386,0.0002968],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004646147,0.0004854323,0.9014419,0.00006528151,0.00018136347,0.017967995,0.0007175719,0.0001593474,0.056319,0.00037561648,0.00046803907,0.017172357],"study_design_scores_gemma":[0.00015083654,0.001984771,0.94301504,0.00002759225,0.00027198214,0.048247643,0.00030917375,0.0007499175,0.004152385,0.00041230107,0.0006439097,0.00003449278],"about_ca_topic_score_codex":0.0011507011,"about_ca_topic_score_gemma":0.000917352,"teacher_disagreement_score":0.0023202323,"about_ca_system_score_codex":0.00014814314,"about_ca_system_score_gemma":0.00008833264,"threshold_uncertainty_score":0.0077619553},"labels":[],"label_agreement":null},{"id":"W2052350491","doi":"10.1172/jci28310","title":"Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":377,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Terry Fox Foundation; National Cancer Institute; National Institutes of Health; Michael Smith Health Research BC; Stem Cell Network","keywords":"Haematopoiesis; Stromal cell; Stem cell; CXC chemokine receptors; Cell biology; Biology; Cell cycle; Stem cell factor; Chemokine; Hematopoietic stem cell; Stromal cell-derived factor 1; Immunology; Cancer research; CXCR4; Cell; Chemokine receptor; Immune system; Genetics","score_opus":0.054878085575127154,"score_gpt":0.32831870119348433,"score_spread":0.2734406156183572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052350491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98482,0.0060025924,0.0043981117,0.00014385002,0.000023299704,0.00003741496,0.0007689526,0.00037280933,0.0034330462],"genre_scores_gemma":[0.98903567,0.002112333,0.0017220658,0.00005423955,0.000014166921,0.00003528893,0.0012303945,0.000036332018,0.0057595135],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999163,0.000009640777,0.0000098690525,0.000014739342,0.000032169068,0.000017188739],"domain_scores_gemma":[0.9997782,0.00003663474,0.00007155974,0.000027766433,0.000025874793,0.000060049897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107539214,0.0003861041,0.00021597948,0.00027990286,0.0001234566,0.00019152039,0.00017237997,0.00020359695,0.0025044922],"category_scores_gemma":[0.00012913808,0.00013949581,0.00014154207,0.00013029296,0.00026168686,0.00014821066,0.00023342189,0.00040521438,0.0009392062],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012573724,0.000026740767,0.0018866749,0.000048370643,0.000006661625,0.00013236156,0.00003963019,0.000050111496,0.9872328,0.00025026497,0.000106535896,0.010094142],"study_design_scores_gemma":[0.000018260198,0.00075324764,0.030848805,0.00001678372,0.000022477763,0.0019496512,0.00005390885,0.00034072387,0.95849955,0.00020748473,0.0072831707,0.0000057971793],"about_ca_topic_score_codex":0.00028387824,"about_ca_topic_score_gemma":0.00039085958,"teacher_disagreement_score":0.0025044922,"about_ca_system_score_codex":0.00015086432,"about_ca_system_score_gemma":0.00016065837,"threshold_uncertainty_score":0.0083783865},"labels":[],"label_agreement":null},{"id":"W2052493267","doi":"10.1172/jci11902","title":"Bonzo/CXCR6 expression defines type 1–polarized T-cell subsets with extralymphoid tissue homing potential","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":358,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; York University; Leukemia and Lymphoma Society; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"Cytotoxic T cell; Interleukin 21; Natural killer T cell; Cell biology; IL-2 receptor; CD40; CXCL16; CCL5; ZAP70; Antigen-presenting cell; Granzyme B; Homing (biology); T cell; CXCR3; Biology; Granzyme; C-C chemokine receptor type 7; Interleukin 12; CD28; Priming (agriculture); CD8; Chemokine receptor; Chemokine; Immunology; Inflammation; Immune system; Perforin; In vitro","score_opus":0.038766747480512585,"score_gpt":0.3046622840009077,"score_spread":0.26589553652039516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052493267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99674904,0.001198771,0.00062623766,0.000026214404,0.00000687615,0.000013850998,0.00015750874,0.00001544859,0.001206049],"genre_scores_gemma":[0.9967507,0.00069682655,0.0010366912,0.000037280457,0.00001584194,0.000015305328,0.0005227549,0.000011400907,0.0009132781],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976367,0.0000429203,0.000013139205,0.000036848196,0.000028662256,0.00011480373],"domain_scores_gemma":[0.9999206,0.000011271441,0.000024952207,0.000008389263,0.000010833852,0.00002392631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014452766,0.00020793424,0.0002221148,0.00034511797,0.00019474218,0.0004579552,0.00010276221,0.00026849308,0.0015798701],"category_scores_gemma":[0.00010832656,0.00016933565,0.00018063515,0.00016569259,0.00015468163,0.00023816832,0.00019760305,0.00024401961,0.0005713225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035763407,0.000028619075,0.003399614,0.00003534092,0.0000038376634,0.000080322985,0.0000400885,0.00006660273,0.99262035,0.000141498,0.000054516615,0.0031716109],"study_design_scores_gemma":[0.00012021607,0.0013483253,0.18481745,0.00004659801,0.00007336225,0.007647013,0.00034960092,0.0043988083,0.7897088,0.0004058367,0.011041958,0.000042121806],"about_ca_topic_score_codex":0.00028919478,"about_ca_topic_score_gemma":0.00047743812,"teacher_disagreement_score":0.0015798701,"about_ca_system_score_codex":0.00022438001,"about_ca_system_score_gemma":0.00008683858,"threshold_uncertainty_score":0.0052852035},"labels":[],"label_agreement":null},{"id":"W2052554962","doi":"10.1172/jci28549","title":"Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":1305,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"CCR2; CX3CR1; Monocyte; Chemokine receptor; Chemokine; CC chemokine receptors; Immunology; CD11c; Biology; Inflammation; Phenotype; Gene; Biochemistry","score_opus":0.12593836580196016,"score_gpt":0.41590416755424525,"score_spread":0.2899658017522851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052554962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99568367,0.0022879546,0.001044437,0.000025705354,0.000007198358,0.000019347262,0.0002534379,0.000027284197,0.0006508812],"genre_scores_gemma":[0.9951208,0.0012934997,0.0016023371,0.00007441029,0.00002007998,0.00003716969,0.00046289436,0.000011007645,0.0013778777],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974436,0.00003486235,0.000028851837,0.00004807867,0.000049375703,0.000094496034],"domain_scores_gemma":[0.9998839,0.000009227955,0.000037617163,0.0000145957965,0.00002721767,0.00002745082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001750667,0.00025115494,0.0003255246,0.00035138382,0.00015514501,0.00047185217,0.00009399215,0.00023459549,0.0007514725],"category_scores_gemma":[0.0001331168,0.00014386163,0.00021950545,0.0002805831,0.00009557755,0.00021057083,0.00022080881,0.00022713929,0.0003340594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027237658,0.000021579897,0.0085040685,0.000039798433,0.00001126485,0.00015761692,0.000090262234,0.000035288118,0.98797125,0.0001290424,0.000059924503,0.0027075054],"study_design_scores_gemma":[0.000065822016,0.0012690526,0.43840393,0.000073500174,0.00020312639,0.0048894924,0.00059540966,0.0014218803,0.5441404,0.00031512778,0.008563272,0.000058934093],"about_ca_topic_score_codex":0.0007338599,"about_ca_topic_score_gemma":0.0011223273,"teacher_disagreement_score":0.0007514725,"about_ca_system_score_codex":0.00013288371,"about_ca_system_score_gemma":0.00012955743,"threshold_uncertainty_score":0.0025138855},"labels":[],"label_agreement":null},{"id":"W2053098204","doi":"10.1172/jci42142","title":"Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life","year":2010,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Retinopathy of Prematurity Studies","field":"Medicine","cited_by":275,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont; Montreal Children's Hospital; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research; Canadian Stroke Network; Canadian Child Health Clinician Scientist Program; Charles A. King Trust; Health Sciences Centre Foundation; Heart and Stroke Foundation of Canada","keywords":"Retinopathy of prematurity; Medicine; Neovascularization; Retinal; Retinopathy; Retinal detachment; Retina; Pathogenesis; Ophthalmology; Macular degeneration; Ischemia; Hypoxia (environmental); Retinal Disorder; Pathology; Angiogenesis; Neuroscience; Internal medicine; Biology; Pregnancy; Endocrinology; Gestational age","score_opus":0.346324176527859,"score_gpt":0.43272537660193033,"score_spread":0.08640120007407132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053098204","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011894753,0.99843913,0.0001234464,0.0004397923,0.00014449355,0.0000026504472,0.0000057465063,0.000004679997,0.000721141],"genre_scores_gemma":[0.00062238437,0.99848205,0.00023867737,0.00017419181,0.00018572938,0.000004244966,0.000008835381,7.2580576e-7,0.0002830536],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998172,0.00004459445,0.000029266062,0.000025404279,0.000068112124,0.0000154195],"domain_scores_gemma":[0.9996501,0.00015635954,0.000049375056,0.000012298243,0.00009496211,0.00003695789],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006165404,0.0007120371,0.0015686123,0.0027268222,0.00033953768,0.0011117524,0.0007800608,0.0013292764,0.0021437919],"category_scores_gemma":[0.00076281023,0.00018992247,0.00029484663,0.002352943,0.00075219077,0.002190755,0.0007055659,0.0014574107,0.0014093644],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061578176,0.0000868409,0.00040870727,0.022209384,0.00008416675,0.0005816771,0.00029036548,0.00019357883,0.0026030242,0.0063286163,0.02571661,0.94143546],"study_design_scores_gemma":[0.000014239833,0.00015762442,0.0024258192,0.0087271,0.00010139024,0.0049585085,0.0004192211,0.00009107477,0.0006634262,0.00465337,0.9777656,0.000022562566],"about_ca_topic_score_codex":0.0012071185,"about_ca_topic_score_gemma":0.0017395124,"teacher_disagreement_score":0.0027268222,"about_ca_system_score_codex":0.000601307,"about_ca_system_score_gemma":0.00129863,"threshold_uncertainty_score":0.00717175},"labels":[],"label_agreement":null},{"id":"W2053441895","doi":"10.1172/jci25052","title":"TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Purine nucleoside phosphorylase; Intracellular; Purine; In vivo; Purine metabolism; Immune system; Ex vivo; Enzyme; Nucleoside; Biology; Pharmacology; Chemistry; Immunology; Biochemistry","score_opus":0.02774581565182042,"score_gpt":0.31336724389080267,"score_spread":0.28562142823898223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053441895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9547236,0.0033663264,0.03113266,0.0009799474,0.00027218656,0.0003135416,0.0029084063,0.0024372884,0.0038660914],"genre_scores_gemma":[0.9563503,0.0028939971,0.026380315,0.00024861537,0.00006789031,0.00033166836,0.0022716997,0.00047795163,0.010977551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994301,0.000111706046,0.00009404637,0.00014842859,0.000111052796,0.00010467784],"domain_scores_gemma":[0.9994149,0.00008816936,0.00022888745,0.000073321244,0.000039323735,0.00015541363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005367612,0.0009933879,0.00058821397,0.0011650493,0.00037450882,0.0006556254,0.0007428122,0.0012562164,0.0016856359],"category_scores_gemma":[0.0003322072,0.0005835629,0.00057573064,0.00036173797,0.00095816766,0.00064714445,0.0003715735,0.0017832291,0.00092406146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018201333,0.000063309926,0.00008905442,0.00005710609,0.0000136266635,0.00013595725,0.000028830926,0.00012390387,0.99707425,0.00038600265,0.000093906674,0.0017519825],"study_design_scores_gemma":[0.000095073556,0.00048582235,0.00082672463,0.000028576003,0.000044106637,0.00064620486,0.00002364975,0.0015609999,0.9906266,0.00018440968,0.0054671783,0.000010792192],"about_ca_topic_score_codex":0.00062855094,"about_ca_topic_score_gemma":0.0008159178,"teacher_disagreement_score":0.0016856359,"about_ca_system_score_codex":0.0007103095,"about_ca_system_score_gemma":0.00053929526,"threshold_uncertainty_score":0.0056390762},"labels":[],"label_agreement":null},{"id":"W2053530470","doi":"10.1172/jci9147","title":"Suppressed smooth muscle proliferation and inflammatory cell invasion after arterial injury in elafin-overexpressing mice","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; University Health Network; Hospital for Sick Children","funders":"Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Elafin; Cell growth; Inflammation; Cell injury; Cell biology; Cancer research; Myocyte; Medicine; Biology; Chemistry; Internal medicine; Immunology; Apoptosis; Biochemistry","score_opus":0.04240796166594906,"score_gpt":0.3488913828416235,"score_spread":0.30648342117567445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053530470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973302,0.0003954464,0.0010808939,0.00010820382,0.000016626129,0.000021868897,0.00018033944,0.0001419227,0.00072455104],"genre_scores_gemma":[0.98999876,0.0007525513,0.002179973,0.00010125377,0.000031362975,0.00007854032,0.000593785,0.000078641795,0.006185129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999746,0.000050233284,0.000027493717,0.00005582953,0.000050269467,0.00007004556],"domain_scores_gemma":[0.9995426,0.000044833538,0.0001654917,0.000043399905,0.000030957617,0.00017266591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031117364,0.00085143297,0.00040970612,0.0010733512,0.00031040533,0.00048316075,0.00024247362,0.00063170504,0.0020427103],"category_scores_gemma":[0.00026321146,0.00045051673,0.00029254833,0.00026178543,0.0005506103,0.00037380756,0.00024618144,0.0009566338,0.0005977654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067671004,0.00022485705,0.00037041702,0.000024287616,0.000006558279,0.00020541761,0.00003820811,0.00003383779,0.9969432,0.00012302422,0.0000377032,0.0013157458],"study_design_scores_gemma":[0.00050305447,0.00512698,0.03142773,0.00004071542,0.000106488034,0.0028562106,0.00014022454,0.0020327826,0.95431346,0.00029860326,0.003129131,0.000024711808],"about_ca_topic_score_codex":0.00038188123,"about_ca_topic_score_gemma":0.0006190266,"teacher_disagreement_score":0.0020427103,"about_ca_system_score_codex":0.0002970508,"about_ca_system_score_gemma":0.00019263409,"threshold_uncertainty_score":0.0068335533},"labels":[],"label_agreement":null},{"id":"W2054256748","doi":"10.1172/jci69296","title":"Where hypertension happens","year":2013,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Blood Pressure and Hypertension Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Renin–angiotensin system; Mechanism (biology); Essential hypertension; Pathophysiology of hypertension; Intensive care medicine; Bioinformatics; Internal medicine; Blood pressure; Biology; Philosophy; Epistemology","score_opus":0.1735329966809813,"score_gpt":0.368624125692274,"score_spread":0.1950911290112927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054256748","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004127273,0.015358733,0.000457767,0.9321645,0.026775917,0.00002631229,0.00006963541,0.00008319735,0.020936608],"genre_scores_gemma":[0.0539531,0.01712981,0.0005719763,0.8357605,0.075360455,0.000033524677,0.000056465116,0.000044558878,0.017089644],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99899274,0.00030150195,0.00010236821,0.00014244932,0.00022812952,0.00023266223],"domain_scores_gemma":[0.99872786,0.0004121043,0.00015684585,0.000065644614,0.00026872818,0.00036890342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006508227,0.00042734784,0.0006050668,0.0004782576,0.0021052593,0.0017804378,0.000481849,0.009936029,0.006838137],"category_scores_gemma":[0.004969634,0.00022663547,0.00052290794,0.00034487687,0.0013534693,0.003493971,0.00083801214,0.010855302,0.004121954],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016307025,0.00011258486,0.01174584,0.00038638778,0.000069223934,0.086008236,0.0021304372,0.000067242305,0.0013123415,0.017469497,0.8055031,0.075032026],"study_design_scores_gemma":[0.00012982961,0.00011345461,0.0068329656,0.0012657132,0.00006887739,0.13208826,0.0042867647,0.00027446426,0.0006600697,0.03559375,0.8185902,0.00009568087],"about_ca_topic_score_codex":0.0036896737,"about_ca_topic_score_gemma":0.005992221,"teacher_disagreement_score":0.009936029,"about_ca_system_score_codex":0.0017612231,"about_ca_system_score_gemma":0.0013620387,"threshold_uncertainty_score":0.022875845},"labels":[],"label_agreement":null},{"id":"W2055166353","doi":"10.1172/jci10763","title":"Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":494,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research; Amgen (Canada); Toronto General Hospital; Western University","funders":"National Institute of Dental and Craniofacial Research; Medical Research Council; National Institutes of Health; London Health Sciences Centre; Amgen","keywords":"Osteoprotegerin; Osteoclast; Periodontitis; Dental alveolus; Immunology; Bone resorption; Medicine; Porphyromonas gingivalis; Immune system; RANKL; Bone remodeling; Receptor; Internal medicine; Dentistry; Activator (genetics)","score_opus":0.05223104631802851,"score_gpt":0.3522658271844794,"score_spread":0.3000347808664509,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055166353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97728264,0.01812232,0.0020870126,0.00018520816,0.00005406091,0.00009040213,0.00020493717,0.00010910549,0.0018643352],"genre_scores_gemma":[0.994145,0.0026681619,0.0014082065,0.00011847142,0.000035662877,0.00008481827,0.00031025114,0.000010009969,0.0012194999],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999824,0.000042219646,0.000016629598,0.000027311045,0.000034869117,0.000054857028],"domain_scores_gemma":[0.99993384,0.0000097257935,0.000022395785,0.000006426727,0.000006021676,0.000021539745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025955166,0.00035394926,0.00036336156,0.00024159394,0.00012076406,0.00030732175,0.00021264899,0.000346948,0.0015387946],"category_scores_gemma":[0.00016437907,0.00013635244,0.00021791915,0.00014576956,0.0003286795,0.0001604312,0.0002687989,0.00058927166,0.00046788275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008715234,0.000121009245,0.0010773152,0.000100332625,0.000007866253,0.00019752549,0.00003200456,0.00010479111,0.9908546,0.00015722084,0.00014084653,0.006334958],"study_design_scores_gemma":[0.0007397147,0.005499557,0.07398925,0.000062324885,0.00016973553,0.0042827856,0.00023999772,0.002786503,0.89023113,0.00084548106,0.021116165,0.000037487574],"about_ca_topic_score_codex":0.0002551346,"about_ca_topic_score_gemma":0.00029286701,"teacher_disagreement_score":0.0015387946,"about_ca_system_score_codex":0.00023811815,"about_ca_system_score_gemma":0.00024357352,"threshold_uncertainty_score":0.005147755},"labels":[],"label_agreement":null},{"id":"W2055785133","doi":"10.1172/jci15912","title":"Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Drug Abuse; National Institutes of Health; National Eye Institute; Institut National de la Santé et de la Recherche Médicale","keywords":"Prolactin; Prolactin cell; Prolactinoma; Endocrinology; Internal medicine; Dopamine; Dopamine receptor; Signal transduction; Receptor; Biology; Neuroscience; Cell biology; Medicine; Hormone","score_opus":0.08281571445697379,"score_gpt":0.3309611466416061,"score_spread":0.2481454321846323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055785133","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98242915,0.0022859625,0.0050725485,0.00057147804,0.0001364017,0.00015720206,0.0048468304,0.00094070233,0.0035597223],"genre_scores_gemma":[0.96365607,0.0026156353,0.009513959,0.00039844762,0.00009134785,0.000535853,0.004602835,0.0007642454,0.017821683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998684,0.00015234239,0.0002023171,0.0004231346,0.0003181523,0.0002201829],"domain_scores_gemma":[0.9988914,0.00014014641,0.00042647473,0.0001162096,0.000043596687,0.0003822621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040145847,0.0015286308,0.0006596165,0.0016700267,0.0004809313,0.001069785,0.00080324506,0.0013246994,0.0051171533],"category_scores_gemma":[0.00028830365,0.0011931371,0.0009213125,0.0005202569,0.00096260133,0.0005821299,0.0007418522,0.0022777782,0.002065411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044948678,0.00012013079,0.00027736358,0.00003635343,0.000016997647,0.00018650474,0.000029452769,0.00006301416,0.9974546,0.00025914915,0.00007835077,0.0010286082],"study_design_scores_gemma":[0.00024729228,0.0011499675,0.007999053,0.00004041014,0.00007380181,0.0020195825,0.00012304778,0.0013312083,0.9814176,0.00021502915,0.00534626,0.00003665229],"about_ca_topic_score_codex":0.0010170978,"about_ca_topic_score_gemma":0.0022111614,"teacher_disagreement_score":0.0051171533,"about_ca_system_score_codex":0.00081729784,"about_ca_system_score_gemma":0.00054955174,"threshold_uncertainty_score":0.017118573},"labels":[],"label_agreement":null},{"id":"W2056110140","doi":"10.1172/jci33673","title":"VEGF-B inhibits apoptosis via VEGFR-1–mediated suppression of the expression of BH3-only protein genes in mice and rats","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Eye Institute; National Institute on Aging; National Institutes of Health; American Health Assistance Foundation; University of North Texas; School of Medicine, Boston University; Glaucoma Research Foundation","keywords":"Apoptosis; Biology; Gene; Bcl-2 family; Cell biology; Gene expression; Cancer research; Programmed cell death; Molecular biology; Genetics","score_opus":0.04201217221208846,"score_gpt":0.31926473139286765,"score_spread":0.2772525591807792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056110140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901877,0.00324215,0.0036044938,0.00027963892,0.0000680396,0.000062470535,0.000364438,0.00037369676,0.0018173228],"genre_scores_gemma":[0.98889714,0.002511898,0.0033672778,0.00012942127,0.000027867834,0.0001021462,0.0005160324,0.00007077579,0.00437747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999775,0.000055174118,0.000027433542,0.00003621497,0.00003591094,0.00007039462],"domain_scores_gemma":[0.9997428,0.000028356257,0.00009902168,0.00003240876,0.00002217458,0.00007521063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003616428,0.0006423952,0.00044447614,0.0010252583,0.00021411588,0.00030744015,0.00035539846,0.0003862438,0.0011726839],"category_scores_gemma":[0.00020926105,0.00028209348,0.0003394152,0.00019157647,0.00047739947,0.00031290745,0.00017425849,0.00083613413,0.0003819089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009601445,0.00029871112,0.000227892,0.000058385514,0.000021999722,0.000075339965,0.000021833286,0.0001493176,0.9938279,0.0003282922,0.00014129489,0.003888971],"study_design_scores_gemma":[0.00020213399,0.0034647335,0.0028727748,0.000020121379,0.000041528696,0.00033945407,0.00003263083,0.0013324989,0.9891311,0.0002756023,0.00227399,0.000013514189],"about_ca_topic_score_codex":0.0011582252,"about_ca_topic_score_gemma":0.0010619087,"teacher_disagreement_score":0.0011726839,"about_ca_system_score_codex":0.00042754156,"about_ca_system_score_gemma":0.00034784336,"threshold_uncertainty_score":0.0039230585},"labels":[],"label_agreement":null},{"id":"W2057046598","doi":"10.1172/jci46315","title":"Recent advances in the molecular pathophysiology of atrial fibrillation","year":2011,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":544,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft; Institut de Cardiologie de Montréal; European Commission; Canadian Institutes of Health Research; Mitacs; Heart and Stroke Foundation of Canada","keywords":"Atrial fibrillation; Medicine; Disease; Reentry; Cardiac arrhythmia; Cardiology; Internal medicine; Pathophysiology; Bioinformatics; Intensive care medicine; Neuroscience; Psychology; Biology","score_opus":0.27283598202317294,"score_gpt":0.4850792628019158,"score_spread":0.21224328077874288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057046598","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006634487,0.99853396,0.00010707964,0.00048184345,0.0003083583,0.000002000982,0.0000049903692,0.000004740412,0.00049065443],"genre_scores_gemma":[0.00034601302,0.9986921,0.00016183061,0.00019261272,0.00035586098,0.0000025654583,0.00000918414,6.8331065e-7,0.00023903853],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997732,0.000044599416,0.00004256242,0.000039078706,0.00007843014,0.000022111984],"domain_scores_gemma":[0.99936813,0.00032142954,0.00007407545,0.000019559648,0.00016469439,0.000052188418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008342241,0.0010225066,0.0013216604,0.0019641323,0.00037568097,0.0011015591,0.00093303865,0.0015086038,0.0029025064],"category_scores_gemma":[0.0011453567,0.0002836672,0.0005117608,0.0020687554,0.0006779158,0.002042861,0.0009092444,0.002386369,0.0021575822],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010695361,0.00009864226,0.00025396282,0.015247169,0.000098526616,0.0005057793,0.00010648199,0.0004031928,0.0024192778,0.0056370245,0.037455574,0.9376674],"study_design_scores_gemma":[0.000021063273,0.000084992,0.0009027072,0.0035220513,0.00013324987,0.0024964453,0.000102539576,0.00010125376,0.0005306977,0.0044515044,0.9876252,0.000028330518],"about_ca_topic_score_codex":0.0008522507,"about_ca_topic_score_gemma":0.0014601634,"teacher_disagreement_score":0.0029025064,"about_ca_system_score_codex":0.0007594147,"about_ca_system_score_gemma":0.0012378821,"threshold_uncertainty_score":0.009709835},"labels":[],"label_agreement":null},{"id":"W2057218469","doi":"10.1172/jci67227","title":"AMPK, insulin resistance, and the metabolic syndrome","year":2013,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":867,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes; Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health","keywords":"AMPK; Insulin resistance; Hyperinsulinemia; Metabolic syndrome; Dyslipidemia; Medicine; Endocrinology; Type 2 diabetes; Internal medicine; Diabetes mellitus; Protein kinase A; AMP-activated protein kinase; Insulin; Bioinformatics; Biology; Kinase; Genetics","score_opus":0.08040403835330859,"score_gpt":0.3820727877537857,"score_spread":0.30166874940047717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057218469","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000084117935,0.99847394,0.00007666318,0.00028040248,0.00023013623,0.0000030602023,0.000012744096,0.0000057113134,0.0008331644],"genre_scores_gemma":[0.00041657692,0.9986846,0.0001022153,0.00011961205,0.00019394317,0.0000038357707,0.000019252631,8.0409785e-7,0.00045920644],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998574,0.000023306768,0.000023787656,0.000024798808,0.000054910368,0.000015609863],"domain_scores_gemma":[0.99980336,0.00006819874,0.000033066142,0.000005787473,0.00006263701,0.000026965596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036900153,0.00078129466,0.0012696576,0.0025939657,0.0003404154,0.0010247149,0.000698428,0.0010353383,0.0038190337],"category_scores_gemma":[0.00053744693,0.00025191566,0.00036555185,0.002503507,0.0004671982,0.0010735415,0.00069988956,0.0016982048,0.002645066],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008092571,0.00007986491,0.00029847503,0.014035081,0.00008289238,0.00043619255,0.00007241836,0.0002233559,0.0014680008,0.0040327315,0.038389962,0.9408001],"study_design_scores_gemma":[0.0000140895045,0.00006175873,0.0014015896,0.0039938125,0.00008230858,0.0032385672,0.00008107548,0.000055919434,0.00027301747,0.00270987,0.9880668,0.000021318629],"about_ca_topic_score_codex":0.00094109983,"about_ca_topic_score_gemma":0.0014657234,"teacher_disagreement_score":0.0038190337,"about_ca_system_score_codex":0.0005625761,"about_ca_system_score_gemma":0.0010173304,"threshold_uncertainty_score":0.012776017},"labels":[],"label_agreement":null},{"id":"W2057419293","doi":"10.1172/jci66746","title":"Better tools for assessing osteoporosis","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and osteoporosis research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Osteoporosis; Quantitative computed tomography; Dual energy; Medicine; Skeleton (computer programming); Dual-energy X-ray absorptiometry; Osteoporotic fracture; Axial skeleton; Radiology; Nuclear medicine; Bone density; Bone mineral; Internal medicine; Anatomy","score_opus":0.2712895652214182,"score_gpt":0.5006644507778752,"score_spread":0.22937488555645702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057419293","genre_codex":"review","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028005756,0.57438254,0.22705856,0.09663511,0.017248668,0.00094043155,0.006709427,0.003379953,0.04563949],"genre_scores_gemma":[0.15791582,0.18482384,0.5810837,0.037718356,0.014185031,0.0020386644,0.0044417023,0.0006560662,0.017136827],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9843837,0.0075906315,0.001955888,0.0016699175,0.0039347205,0.00046521428],"domain_scores_gemma":[0.9809373,0.006897856,0.0016546892,0.002859957,0.0066265534,0.0010236681],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.021943908,0.002217824,0.0026474444,0.011123004,0.0011745078,0.0058930265,0.0021157204,0.004572097,0.011442936],"category_scores_gemma":[0.03751548,0.00077018054,0.0018837855,0.005332868,0.002605058,0.009245806,0.0036066487,0.0055959155,0.004727353],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066572387,0.0005019683,0.028712844,0.0030373442,0.00048806905,0.00049894943,0.0011563936,0.00057043205,0.007982994,0.044532318,0.060884308,0.85096866],"study_design_scores_gemma":[0.00043014574,0.0015680541,0.055683557,0.0076683597,0.0011015454,0.006943478,0.0018336448,0.0032451628,0.0054692766,0.13243513,0.7830468,0.0005748487],"about_ca_topic_score_codex":0.0024282155,"about_ca_topic_score_gemma":0.002756601,"teacher_disagreement_score":0.021943908,"about_ca_system_score_codex":0.0013911382,"about_ca_system_score_gemma":0.0020740724,"threshold_uncertainty_score":0.11605191},"labels":[],"label_agreement":null},{"id":"W2057994513","doi":"10.1172/jci41407","title":"GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; McMaster University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; British Heart Foundation","keywords":"Adrenergic; GSK-3; Muscle hypertrophy; Internal medicine; Endocrinology; Medicine; GSK3B; Glycogen synthase; Phosphorylation; Heart failure; Glycogen; Biology; Cell biology; Receptor","score_opus":0.019575994039745654,"score_gpt":0.32572500315561437,"score_spread":0.30614900911586873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057994513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835488,0.005084523,0.006228891,0.00066614844,0.00012257001,0.00006460599,0.0008829612,0.0005129846,0.0028886977],"genre_scores_gemma":[0.987628,0.0030964387,0.0039843707,0.00021079241,0.00005066206,0.000113831375,0.0005585672,0.000099807716,0.004257598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998062,0.0000380178,0.000024076582,0.00004541373,0.000043158227,0.000043101754],"domain_scores_gemma":[0.999747,0.000023798142,0.00012148105,0.000028850756,0.000010770762,0.00006817908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031244507,0.0006745569,0.00030447103,0.00066942093,0.00019760663,0.0006341518,0.0003190688,0.0004388108,0.0014079992],"category_scores_gemma":[0.00021945,0.00049328303,0.00052278535,0.00021834322,0.0007189065,0.0003872712,0.0002954891,0.0011557714,0.0007086844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005988783,0.00006619464,0.0006635392,0.000041809875,0.000017271988,0.0001768994,0.00003396436,0.00012870233,0.9946656,0.0004609157,0.00012779213,0.0030184076],"study_design_scores_gemma":[0.00050334836,0.0014930989,0.02573009,0.00007423588,0.00012167772,0.0016442557,0.00013060888,0.0024154442,0.95867956,0.001341909,0.007839485,0.000026316935],"about_ca_topic_score_codex":0.0002996849,"about_ca_topic_score_gemma":0.0007372803,"teacher_disagreement_score":0.0014079992,"about_ca_system_score_codex":0.00041814244,"about_ca_system_score_gemma":0.00035793043,"threshold_uncertainty_score":0.004710257},"labels":[],"label_agreement":null},{"id":"W2058086184","doi":"10.1172/jci38832","title":"Disruptive insights in psychiatry: transforming a clinical discipline","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychiatry; Bipolar disorder; Depression (economics); Medicine; Mental illness; Psychology; Mental health; Cognition","score_opus":0.1070947486217826,"score_gpt":0.4654497129746095,"score_spread":0.35835496435282693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058086184","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021344614,0.55838776,0.0045325328,0.3990071,0.017372452,0.000033178414,0.000028581459,0.000113237256,0.018390728],"genre_scores_gemma":[0.076065876,0.7506485,0.009073457,0.09758122,0.06161671,0.0001059891,0.000045416415,0.00006503082,0.0047978605],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966523,0.0019256638,0.00022753364,0.00017639944,0.00079372403,0.00022440076],"domain_scores_gemma":[0.9887193,0.006471866,0.0005787754,0.0006069481,0.0018419616,0.0017810416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0073735653,0.0007362103,0.0012566395,0.0026799121,0.0022613702,0.0060508824,0.0014131571,0.006539485,0.0026345719],"category_scores_gemma":[0.006795244,0.00031761566,0.0005627877,0.0016590442,0.017239489,0.0098703625,0.00476863,0.013808352,0.00080758287],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016125944,0.00035232073,0.0024228892,0.0031971952,0.00007664867,0.0019311578,0.006844992,0.00031441633,0.0009205059,0.29028577,0.18742736,0.5060655],"study_design_scores_gemma":[0.00010168088,0.00027718442,0.0023846657,0.0031370241,0.00004142649,0.004313964,0.0076978863,0.00032424505,0.00019331684,0.36771256,0.61375165,0.0000644082],"about_ca_topic_score_codex":0.0018819422,"about_ca_topic_score_gemma":0.00399779,"teacher_disagreement_score":0.0073735653,"about_ca_system_score_codex":0.0038527693,"about_ca_system_score_gemma":0.008379744,"threshold_uncertainty_score":0.038995624},"labels":[],"label_agreement":null},{"id":"W2058262736","doi":"10.1172/jci16253","title":"Energy expenditure, sex, and endogenous fuel availability in humans","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"Sundhed og Sygdom, Det Frie Forskningsråd; U.S. Public Health Service; National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; Medical Research Council; Mayo Foundation for Medical Education and Research","keywords":"Respiratory quotient; Lipolysis; Adipose tissue; Endocrinology; Internal medicine; Obesity; Basal metabolic rate; Resting energy expenditure; Energy expenditure; Biology; Medicine; Chemistry","score_opus":0.12020181993678392,"score_gpt":0.36600020029785185,"score_spread":0.24579838036106794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058262736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94525653,0.038865365,0.0007708813,0.0008312919,0.00012305185,0.000015666474,0.00069955114,0.000041352334,0.013396368],"genre_scores_gemma":[0.9921638,0.005172282,0.00030051314,0.00023061433,0.00009613894,0.000012316221,0.00022474042,0.000010559547,0.0017890576],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9999423,0.000020373456,0.000005116645,0.000013428379,0.0000100232755,0.000008807588],"domain_scores_gemma":[0.9998951,0.00003218514,0.000028162693,0.000010000678,0.000008859782,0.00002573861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017241514,0.00012812749,0.00020288382,0.00029902536,0.0001335832,0.00045047404,0.00007380372,0.0001900839,0.0019192812],"category_scores_gemma":[0.00063322403,0.00009012333,0.00009694997,0.00029601355,0.00022544665,0.00018416629,0.00017660581,0.00014609238,0.0004002288],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037062827,0.0002762446,0.8123371,0.00028644438,0.00039976084,0.001561117,0.00054114516,0.00043061542,0.010318949,0.002152986,0.0040159924,0.16397335],"study_design_scores_gemma":[0.00003237017,0.00042624705,0.989924,0.000034485944,0.00006320937,0.0019261342,0.00011851543,0.00022983275,0.00034452564,0.0014498557,0.005440969,0.000009975294],"about_ca_topic_score_codex":0.0007004544,"about_ca_topic_score_gemma":0.0006657797,"teacher_disagreement_score":0.0019192812,"about_ca_system_score_codex":0.000098317985,"about_ca_system_score_gemma":0.000065886066,"threshold_uncertainty_score":0.0064206123},"labels":[],"label_agreement":null},{"id":"W2059241988","doi":"10.1172/jci33010","title":"STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute; National Institutes of Health; Leukemia and Lymphoma Society","keywords":"Megakaryocyte; STAT5; Ectopic expression; Thrombopoiesis; STAT1; Gene knockdown; Biology; Thrombopoietin; Cell biology; Phosphorylation; Cancer research; STAT3; GATA1; Megakaryocytopoiesis; Immunology; Progenitor cell; Haematopoiesis; Stem cell; Cell culture; Genetics","score_opus":0.06806310014251697,"score_gpt":0.39242720317645696,"score_spread":0.32436410303394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059241988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9823339,0.0037643432,0.0061072893,0.00065768935,0.00010397621,0.00010682979,0.0020941356,0.0005307147,0.0043011187],"genre_scores_gemma":[0.98675704,0.0019161381,0.0038076043,0.00022871129,0.00002571621,0.00012107028,0.0011618148,0.00009855417,0.005883284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997609,0.00004642779,0.000027362139,0.000059880957,0.000050488678,0.00005483929],"domain_scores_gemma":[0.99982506,0.00001867355,0.0000684546,0.000016136986,0.000008073338,0.00006365561],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024257395,0.0005320733,0.00028769328,0.0005996636,0.00024627912,0.0003866037,0.00030584013,0.0005202549,0.0032576013],"category_scores_gemma":[0.00010894812,0.00039622997,0.00040353386,0.0002293829,0.0004911909,0.00025748322,0.00035960088,0.0012245306,0.00093083875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042332095,0.000060056223,0.00035318505,0.000075674805,0.000008761214,0.0001376767,0.000027501803,0.00009902684,0.9960633,0.0006480038,0.00013831024,0.0019651111],"study_design_scores_gemma":[0.00028329404,0.0009834649,0.013742026,0.000065424814,0.0000798044,0.0014193085,0.000079812766,0.0025683744,0.97047573,0.0006486199,0.009637271,0.000016807915],"about_ca_topic_score_codex":0.00027447272,"about_ca_topic_score_gemma":0.0006388528,"teacher_disagreement_score":0.0032576013,"about_ca_system_score_codex":0.0003700739,"about_ca_system_score_gemma":0.00027814895,"threshold_uncertainty_score":0.010897756},"labels":[],"label_agreement":null},{"id":"W2059754026","doi":"10.1172/jci46276","title":"Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agricultural Research Institute of Ontario; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; FightSMA; University of Ottawa; Universidad de Granada; Spinal Muscular Atrophy Foundation","keywords":"SMN1; Spinal muscular atrophy; SMA*; Motor neuron; STAT5; Downregulation and upregulation; Biology; Prolactin; Endocrinology; Internal medicine; Cancer research; Spinal cord; Cell biology; Signal transduction; Gene; Neuroscience; Medicine; Hormone; Genetics","score_opus":0.13418759534044758,"score_gpt":0.36911202970049806,"score_spread":0.23492443436005048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059754026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927568,0.0026555234,0.0018265641,0.00037743425,0.00008256845,0.000033986613,0.0006164627,0.00022568493,0.0014250131],"genre_scores_gemma":[0.98881847,0.0019453159,0.0029097362,0.00012750908,0.000032808017,0.00011318298,0.00089089776,0.000050358885,0.005111703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997266,0.00008466777,0.000027023456,0.00004169976,0.000066537985,0.00005346232],"domain_scores_gemma":[0.99983203,0.000020094782,0.000058835798,0.000013640943,0.000012495341,0.00006285237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024049515,0.0005739147,0.00043072214,0.00059258426,0.00017263294,0.0002883402,0.00020767449,0.00048522194,0.0015536019],"category_scores_gemma":[0.00012862057,0.00026660494,0.00044479338,0.00019142564,0.00034725558,0.0002458793,0.0001881889,0.0010843498,0.00044120374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007714572,0.000112103815,0.00019809864,0.000040002047,0.000010218238,0.00012214785,0.000019076857,0.000060023736,0.99718153,0.000052533185,0.0000825928,0.0013501381],"study_design_scores_gemma":[0.00033506486,0.005024068,0.009580763,0.000029829434,0.00009726549,0.00073446915,0.00008559012,0.0025810178,0.9769594,0.00011843447,0.004431125,0.000022993645],"about_ca_topic_score_codex":0.00072927185,"about_ca_topic_score_gemma":0.0015057966,"teacher_disagreement_score":0.0015536019,"about_ca_system_score_codex":0.000434187,"about_ca_system_score_gemma":0.0002669669,"threshold_uncertainty_score":0.0051972866},"labels":[],"label_agreement":null},{"id":"W2060571859","doi":"10.1172/jci42497","title":"Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":171,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Synchrotron Light Research Institute; Banting and Best Diabetes Centre, University of Toronto; Novo Nordisk; University of Toronto","keywords":"Endocrinology; Internal medicine; Glucose homeostasis; Incretin; Glucagon-like peptide-1; PDX1; Biology; Pancreatic islets; Glucagon-like peptide 1 receptor; Insulin; Carbohydrate metabolism; Glucagon; Islet; Receptor; Agonist; Type 2 diabetes; Insulin resistance; Diabetes mellitus; Medicine","score_opus":0.08783127618807195,"score_gpt":0.34515637841943836,"score_spread":0.2573251022313664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060571859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9058171,0.00708242,0.033745293,0.0037257457,0.0013101785,0.0013942982,0.020360164,0.0067455783,0.01981934],"genre_scores_gemma":[0.87523276,0.007993837,0.040426545,0.0019582016,0.0005561171,0.00341275,0.018397132,0.0033651346,0.048657414],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813074,0.0002543408,0.00026830586,0.0005753247,0.00043472703,0.00033651266],"domain_scores_gemma":[0.9982368,0.00020168298,0.00053065113,0.0003357079,0.0001148226,0.00058038766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001192969,0.0019268566,0.001297505,0.0026454257,0.0009786534,0.0023720667,0.0020010856,0.0028561607,0.012088103],"category_scores_gemma":[0.00074548245,0.0019105714,0.001646258,0.00087612274,0.0017482676,0.0014129841,0.0012316575,0.005507947,0.005401569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011949296,0.0004541373,0.000275614,0.00018920339,0.000072812916,0.00035677175,0.00011669586,0.00018541193,0.99067605,0.001614551,0.0008133901,0.004050404],"study_design_scores_gemma":[0.003013836,0.0032657785,0.012264956,0.000460607,0.000391037,0.0043942654,0.0002840425,0.004679745,0.91267335,0.00196717,0.0564802,0.00012500999],"about_ca_topic_score_codex":0.00076715497,"about_ca_topic_score_gemma":0.0013296132,"teacher_disagreement_score":0.012088103,"about_ca_system_score_codex":0.0012014346,"about_ca_system_score_gemma":0.0010037988,"threshold_uncertainty_score":0.04043871},"labels":[],"label_agreement":null},{"id":"W2061188756","doi":"10.1172/jci40433","title":"An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Lawson Health Research Institute","keywords":"Metastasis; Cancer research; Cancer; Biology; Biomarker; Melanoma; Downregulation and upregulation; Gene knockdown; Cell culture; Gene; Genetics","score_opus":0.07579314404921753,"score_gpt":0.3616556316969689,"score_spread":0.28586248764775135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061188756","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98766,0.0060941163,0.0039523956,0.00022735908,0.00005680086,0.000036996113,0.00043636025,0.000068718036,0.001467285],"genre_scores_gemma":[0.99415475,0.0018577849,0.0022468816,0.00009432307,0.000025533169,0.000017635073,0.00053235824,0.0000069901657,0.0010637152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998292,0.000035232177,0.000016493663,0.000041682968,0.00006242216,0.000015000975],"domain_scores_gemma":[0.99966526,0.00006646325,0.00012805434,0.000028162262,0.000053213924,0.000058795416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031893532,0.00024017916,0.00021696133,0.00035768977,0.0001274387,0.00031689883,0.00009385914,0.00026621326,0.0006524517],"category_scores_gemma":[0.0005178304,0.0000955248,0.000117612064,0.00026445283,0.00032524447,0.00017681897,0.00015425023,0.00043773316,0.00020580833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013989086,0.00014256877,0.11223256,0.00018738916,0.0000638062,0.0011107179,0.0000454021,0.00027962684,0.86007005,0.00022453356,0.0004923825,0.02375214],"study_design_scores_gemma":[0.00006533481,0.0013073856,0.50662065,0.000035916793,0.000112206435,0.0093892,0.00018225308,0.003748912,0.47161162,0.00054127,0.006354812,0.00003043458],"about_ca_topic_score_codex":0.00038875037,"about_ca_topic_score_gemma":0.0004172046,"teacher_disagreement_score":0.0006524517,"about_ca_system_score_codex":0.000220256,"about_ca_system_score_gemma":0.00016133337,"threshold_uncertainty_score":0.002182722},"labels":[],"label_agreement":null},{"id":"W2062283395","doi":"10.1172/jci29148","title":"Neuropeptide signaling and hydrocephalus: SCO with the flow","year":2006,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pituitary Gland Disorders and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Subcommissural organ; Hydrocephalus; Cerebrospinal fluid; Receptor; Ependymal Cell; Neuropeptide; Adenylate kinase; Internal medicine; Ventricular system; Endocrinology; Medicine; Biology; Neuroscience; Cell biology; Central nervous system; Surgery","score_opus":0.04967839516196598,"score_gpt":0.31895014025923923,"score_spread":0.26927174509727325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062283395","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015359375,0.008727649,0.0005087708,0.9390028,0.024527807,0.000051652805,0.000056702138,0.00012783839,0.011637448],"genre_scores_gemma":[0.14020444,0.016324302,0.0014870743,0.61198646,0.20423962,0.00011523424,0.00007708938,0.00005097907,0.025514781],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995161,0.00015952399,0.000059812024,0.00006356243,0.00012978537,0.000071268325],"domain_scores_gemma":[0.99913436,0.0004939278,0.000093094386,0.000036117217,0.00011592403,0.00012659979],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004414532,0.0007502403,0.000912725,0.00040246567,0.0013121563,0.0010994656,0.0005707491,0.014163961,0.0028871242],"category_scores_gemma":[0.004687812,0.00034507568,0.0005162654,0.00036816593,0.0015239249,0.0015141164,0.00034516765,0.008042997,0.00217547],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006487493,0.0002832883,0.009256892,0.00040724245,0.000056235487,0.19580655,0.00052552205,0.0003023705,0.0030734676,0.0057813935,0.724795,0.05906338],"study_design_scores_gemma":[0.00082004315,0.00061937154,0.014299279,0.00054834224,0.00012766232,0.36171567,0.00087047066,0.0027996143,0.0032482366,0.017954208,0.5968915,0.00010563572],"about_ca_topic_score_codex":0.0013057148,"about_ca_topic_score_gemma":0.0018193576,"teacher_disagreement_score":0.014163961,"about_ca_system_score_codex":0.0018488994,"about_ca_system_score_gemma":0.0008900156,"threshold_uncertainty_score":0.0134148},"labels":[],"label_agreement":null},{"id":"W2062378136","doi":"10.1172/jci11596","title":"Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":705,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hamilton Health Sciences; McMaster University","funders":"National Institutes of Health; National Institute of Neurological Disorders and Stroke; American Heart Association; Office of Research and Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; U.S. Department of Veterans Affairs","keywords":"Endoplasmic reticulum; Hyperhomocysteinemia; Unfolded protein response; Cystathionine beta synthase; Homocysteine; Endocrinology; Steatosis; Internal medicine; Lipogenesis; Cholesterol; Triglyceride; Biology; Fatty liver; Chemistry; Biochemistry; Lipid metabolism; Methionine; Medicine","score_opus":0.03988282685411246,"score_gpt":0.30939198330863005,"score_spread":0.26950915645451756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062378136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976418,0.0012020165,0.000352684,0.00010196806,0.000010184478,0.000008851618,0.000051885952,0.000032241463,0.000598369],"genre_scores_gemma":[0.9985598,0.00064916536,0.00021803226,0.000036106292,0.000014084008,0.0000063842353,0.00009860332,0.0000031946497,0.00041473878],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988866,0.000038540384,0.000013808181,0.000022435988,0.000020018948,0.000016478605],"domain_scores_gemma":[0.99991596,0.000011568475,0.000032894604,0.000010629821,0.000010246345,0.000018722469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011729376,0.0002895722,0.00031884073,0.00022716331,0.00023052409,0.0002022079,0.00005917462,0.00033815007,0.0010676449],"category_scores_gemma":[0.00024211392,0.00011896458,0.00014983841,0.0002564936,0.00025179918,0.0001113644,0.00026513572,0.00028112077,0.00027637096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003855045,0.00012285598,0.03173166,0.00028097836,0.0001346765,0.015069107,0.00024039266,0.00015588515,0.9307434,0.00039413437,0.00046790106,0.016803935],"study_design_scores_gemma":[0.00038074757,0.0039890115,0.4119192,0.00008894234,0.00040522387,0.08921001,0.00052552635,0.0012348251,0.48207566,0.0009231564,0.009212884,0.00003486525],"about_ca_topic_score_codex":0.00020056078,"about_ca_topic_score_gemma":0.0002796513,"teacher_disagreement_score":0.0010676449,"about_ca_system_score_codex":0.00016990902,"about_ca_system_score_gemma":0.000111617424,"threshold_uncertainty_score":0.0035716295},"labels":[],"label_agreement":null},{"id":"W2063400663","doi":"10.1172/jci42703","title":"Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Harvard Digestive Diseases Center, Harvard University; Deutsche Forschungsgemeinschaft; Brigham and Women's Hospital; National Cancer Institute; National Institutes of Health; Cancer Research UK; Crohn's and Colitis Foundation; Lister Institute of Preventive Medicine; Wellcome Trust; National Heart, Lung, and Blood Institute; Crohn's and Colitis Foundation of America","keywords":"Microsomal triglyceride transfer protein; CD1; CD1D; Immune system; Biology; Antigen presentation; Lipid metabolism; Antigen; Chemistry; Lipoprotein; T cell; Immunology; Antigen-presenting cell; Biochemistry; Natural killer T cell; Cholesterol; Very low-density lipoprotein","score_opus":0.02611369904497336,"score_gpt":0.2892956699414767,"score_spread":0.26318197089650336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063400663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952427,0.0009922114,0.0007159158,0.00012263402,0.000025831212,0.000023566243,0.00014970453,0.00007455529,0.002652792],"genre_scores_gemma":[0.99735117,0.00037383777,0.00042613276,0.00007047984,0.000019946296,0.000012209494,0.0002483092,0.000013922236,0.0014839371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988043,0.000026550544,0.000013737167,0.000027344773,0.000026935366,0.000025012481],"domain_scores_gemma":[0.99990535,0.000023262184,0.000022601078,0.000006498702,0.000011512816,0.00003063805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012636512,0.0005719706,0.0002642764,0.00055357954,0.0002641001,0.00022563437,0.00012497698,0.0003961614,0.0027543525],"category_scores_gemma":[0.0002822135,0.00013061664,0.00011161625,0.0001801123,0.00030881524,0.00013233,0.00030683985,0.000317928,0.0006042387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002634296,0.00035731666,0.03627224,0.00024046037,0.000076075325,0.062806316,0.0002565846,0.00019271772,0.8786919,0.00079933414,0.0015242219,0.016148508],"study_design_scores_gemma":[0.0002651628,0.0014874719,0.32433873,0.000097401986,0.00025335402,0.33583158,0.00026028987,0.0028508282,0.3104415,0.0008814761,0.023253514,0.000038746388],"about_ca_topic_score_codex":0.00036814943,"about_ca_topic_score_gemma":0.00021213015,"teacher_disagreement_score":0.0027543525,"about_ca_system_score_codex":0.00018494127,"about_ca_system_score_gemma":0.00011321948,"threshold_uncertainty_score":0.009214282},"labels":[],"label_agreement":null},{"id":"W2064059882","doi":"10.1172/jci35433","title":"Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants","year":2008,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Heart and Stroke Foundation of Canada","keywords":"Phagosome; Phagocytosis; Cell biology; Innate immune system; Biology; Lipid metabolism; Intracellular; Immune system; Pathogen; Microbiology; Immunology; Biochemistry","score_opus":0.11528880576704806,"score_gpt":0.386865450945929,"score_spread":0.2715766451788809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064059882","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023876164,0.9978149,0.0001970724,0.00035944805,0.00027631063,0.0000019261959,0.000004871025,0.0000053575554,0.0011013625],"genre_scores_gemma":[0.0014089548,0.99688977,0.00027215303,0.00025904196,0.00023591123,0.000005094535,0.000010416328,0.0000014452684,0.0009172136],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998567,0.000027090971,0.00001772195,0.000029094763,0.000053351112,0.000015942951],"domain_scores_gemma":[0.99979347,0.00009538566,0.000027303906,0.0000071646978,0.000049667407,0.00002705719],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045279856,0.00059326325,0.0012726627,0.0010821662,0.00028758662,0.0011577879,0.00072268693,0.0015621575,0.001529267],"category_scores_gemma":[0.00044443205,0.00017023351,0.00021671219,0.0012950136,0.00082173693,0.0015153238,0.0005935025,0.0011510518,0.0018044208],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010101428,0.000044975714,0.00027240685,0.007100383,0.000039216957,0.0005014624,0.00009840645,0.0002514551,0.008931869,0.0093123885,0.021559112,0.9517874],"study_design_scores_gemma":[0.000017399825,0.00010368326,0.0010179166,0.0018808199,0.00004911903,0.003365506,0.00016269225,0.000097950164,0.00195672,0.004568976,0.9867578,0.000021469283],"about_ca_topic_score_codex":0.0005733559,"about_ca_topic_score_gemma":0.0008585271,"teacher_disagreement_score":0.0015621575,"about_ca_system_score_codex":0.00071484636,"about_ca_system_score_gemma":0.00072925346,"threshold_uncertainty_score":0.005186677},"labels":[],"label_agreement":null},{"id":"W2064420783","doi":"10.1172/jci77116","title":"MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; University of Texas MD Anderson Cancer Center; Novartis Institutes for BioMedical Research; Brigham and Women's Hospital","keywords":"Intravasation; Metastasis; microRNA; Cancer research; Primary tumor; Biology; Cancer; In vivo; Sarcoma; Circulating tumor cell; Medicine; Pathology; Gene; Genetics","score_opus":0.03296922359700192,"score_gpt":0.31240504952076675,"score_spread":0.2794358259237648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064420783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855381,0.0035576746,0.0055302256,0.00027469287,0.00009350804,0.00011728827,0.0003317058,0.00027186723,0.0042849253],"genre_scores_gemma":[0.9904191,0.0014742407,0.0044268644,0.00008160773,0.000023633525,0.00006253879,0.000304203,0.000029071756,0.0031787665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998037,0.000030523155,0.000018483819,0.000042472562,0.00007273836,0.00003210761],"domain_scores_gemma":[0.9999201,0.000014084539,0.000022916429,0.000008627813,0.000009377316,0.000024870946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021474743,0.00026740303,0.00040560917,0.00017464206,0.00014644818,0.00037841577,0.00015098203,0.00023674629,0.0011264752],"category_scores_gemma":[0.0001797491,0.00018819484,0.00018411572,0.00011097461,0.0003231147,0.00013870966,0.00019705457,0.00061956904,0.00044467658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000696984,0.00003213781,0.0002402288,0.000034526613,0.0000047673607,0.000046477475,0.000010206943,0.00007962472,0.9975319,0.00018688172,0.00008989133,0.0016736832],"study_design_scores_gemma":[0.000046538906,0.0007752406,0.002809341,0.0000071430522,0.00002718243,0.0005433529,0.000018095972,0.0013417228,0.9864915,0.00011285074,0.007821671,0.0000054025495],"about_ca_topic_score_codex":0.0003470772,"about_ca_topic_score_gemma":0.000925533,"teacher_disagreement_score":0.0011264752,"about_ca_system_score_codex":0.00040438512,"about_ca_system_score_gemma":0.00038318947,"threshold_uncertainty_score":0.0037683845},"labels":[],"label_agreement":null},{"id":"W2065426985","doi":"10.1172/jci18555","title":"Impaired pancreatic growth, β cell mass, and β cell function in E2F1 –/– mice","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Centre National de la Recherche Scientifique; Institute of Genetics; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale","keywords":"Function (biology); Cell growth; Pancreatic function; Cell biology; Cell; Cell function; Biology; Chemistry; Endocrinology; Cancer research; Internal medicine; Pancreas; Medicine; Biochemistry","score_opus":0.04430414978812112,"score_gpt":0.307244697278432,"score_spread":0.26294054749031087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065426985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907397,0.0013824189,0.0029703726,0.0002602163,0.0000575503,0.00007093919,0.0023124726,0.00019510185,0.0020111871],"genre_scores_gemma":[0.974855,0.0022649264,0.007292543,0.00029962193,0.000052135998,0.00024966086,0.0029813321,0.000413107,0.011591613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994523,0.00008323733,0.00007456943,0.00016942693,0.00011659621,0.000103845734],"domain_scores_gemma":[0.99898595,0.00022049286,0.0003316053,0.000084674866,0.000045190685,0.00033212782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005786477,0.001464147,0.0005791702,0.0023579798,0.00043112427,0.000896903,0.0005195383,0.0015409999,0.003941786],"category_scores_gemma":[0.00046478113,0.000641768,0.00047974198,0.00053099747,0.001156798,0.00069342833,0.00047770585,0.001987571,0.0008026218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007507318,0.0002922448,0.001181095,0.00004948153,0.000017845588,0.00033668897,0.000055273907,0.00019243684,0.99425995,0.00032484884,0.00012196524,0.0024174424],"study_design_scores_gemma":[0.00023033333,0.0010637422,0.017390355,0.000035823214,0.00005884722,0.0028068845,0.00011449192,0.0013333234,0.9712109,0.000279648,0.0054377,0.00003798893],"about_ca_topic_score_codex":0.000716862,"about_ca_topic_score_gemma":0.0009036099,"teacher_disagreement_score":0.003941786,"about_ca_system_score_codex":0.00047063793,"about_ca_system_score_gemma":0.00025996898,"threshold_uncertainty_score":0.013186574},"labels":[],"label_agreement":null},{"id":"W2066417197","doi":"10.1172/jci34149","title":"Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute; National Institute on Aging; Ontario Institute for Cancer Research; Multiple Myeloma Research Foundation","keywords":"Cyclin D2; Cyclin D1; Cyclin D; Biology; Cancer research; Cyclin; Cyclin A; Cyclin D3; Cyclin A2; Cyclin E; Cell cycle; Molecular biology; Cell biology; Cancer; Genetics","score_opus":0.05357447636482407,"score_gpt":0.36054459710926406,"score_spread":0.30697012074443997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066417197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98033774,0.0073671737,0.0057559093,0.00025080584,0.000037402173,0.0003085247,0.0007930994,0.00025703426,0.0048922915],"genre_scores_gemma":[0.9867424,0.0037463065,0.0044829445,0.000054185515,0.000011719523,0.00012717779,0.0009156424,0.00002216361,0.0038974506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999368,0.0000085235115,0.0000039327597,0.000013744992,0.000020996862,0.000015965072],"domain_scores_gemma":[0.9999449,0.000006800466,0.000014677146,0.000005274338,0.0000095079795,0.000018851708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014017128,0.00043394475,0.00021838193,0.00036137537,0.00016970532,0.00022600494,0.00022100637,0.00023200871,0.0010260801],"category_scores_gemma":[0.00008579653,0.00012635163,0.000161821,0.00022076776,0.00015301982,0.00012839632,0.00013061328,0.00037133446,0.00018647524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022087994,0.0001317255,0.0001856499,0.000053370273,0.0000074512077,0.000043610176,0.00001364013,0.00022179053,0.9938386,0.00026471895,0.00011520539,0.0049033505],"study_design_scores_gemma":[0.0001473544,0.002809847,0.0020899,0.000007841992,0.00003674362,0.0002664282,0.000008182847,0.0006274701,0.9851258,0.000060233015,0.008813316,0.0000069171488],"about_ca_topic_score_codex":0.0015005963,"about_ca_topic_score_gemma":0.004362216,"teacher_disagreement_score":0.0015005963,"about_ca_system_score_codex":0.00063353375,"about_ca_system_score_gemma":0.00036095633,"threshold_uncertainty_score":0.0045966506},"labels":[],"label_agreement":null},{"id":"W2066509904","doi":"10.1172/jci10211","title":"Viral antichemokines: from pathogenesis to drug discovery","year":2000,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Pathogenesis; Drug discovery; Medicine; Virology; Drug; Computational biology; Pharmacology; Bioinformatics; Biology; Immunology","score_opus":0.08667854039801026,"score_gpt":0.3935439624992023,"score_spread":0.30686542210119205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066509904","genre_codex":"review","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011301942,0.7475534,0.0017326875,0.19747391,0.04525485,0.00003326295,0.0002158816,0.0001731342,0.00643264],"genre_scores_gemma":[0.014300593,0.7688695,0.001816321,0.13328218,0.06555853,0.00008607349,0.00030018968,0.00008320733,0.015703393],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986388,0.00035978173,0.000109504355,0.00020106215,0.0005254901,0.00016529586],"domain_scores_gemma":[0.9963122,0.0014001931,0.0002522195,0.0001575722,0.0010576681,0.00082006736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0038440062,0.0008994353,0.0014220631,0.0016879507,0.0008930541,0.0046215313,0.0014422231,0.0047477973,0.007858098],"category_scores_gemma":[0.0059202104,0.00045535216,0.00053705444,0.0012274582,0.0027493446,0.0069973613,0.0025326936,0.008828379,0.0042045075],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003137606,0.00010456995,0.00036940922,0.001437691,0.000064390326,0.00039763912,0.00018995709,0.0003113,0.0019524868,0.04299706,0.6254117,0.32645005],"study_design_scores_gemma":[0.0000830771,0.00014607725,0.00012683003,0.00063906045,0.000020703603,0.00021579904,0.00006850983,0.00017264087,0.0004401129,0.013336583,0.98473233,0.000018333594],"about_ca_topic_score_codex":0.0006592997,"about_ca_topic_score_gemma":0.0017275417,"teacher_disagreement_score":0.007858098,"about_ca_system_score_codex":0.0024536627,"about_ca_system_score_gemma":0.0020662213,"threshold_uncertainty_score":0.026287973},"labels":[],"label_agreement":null},{"id":"W2066987530","doi":"10.1172/jci31854","title":"Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Yasuda Memorial Medical Foundation; Novartis Foundation; Suzuken Memorial Foundation","keywords":"PTEN; Cancer research; Lung; Carcinogenesis; Biology; Tumor suppressor gene; Pathology; Adenocarcinoma; PI3K/AKT/mTOR pathway; Cancer; Medicine; Internal medicine; Cell biology; Signal transduction; Genetics","score_opus":0.027018199640648374,"score_gpt":0.32492952536392494,"score_spread":0.29791132572327655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066987530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896473,0.0016066186,0.0043257293,0.00017397694,0.000053352695,0.00009209354,0.001232935,0.00056763925,0.0023003807],"genre_scores_gemma":[0.9880437,0.0013126652,0.0022903671,0.00008259334,0.00002625791,0.00011463014,0.000949324,0.00016173351,0.007018754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99939203,0.000075021,0.00007353889,0.00016319782,0.00016424002,0.00013194412],"domain_scores_gemma":[0.99915993,0.000070927155,0.0003146889,0.000069658934,0.000043818014,0.0003410283],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003718171,0.0007613193,0.00038229846,0.0014684511,0.00034315343,0.0006564767,0.0005337053,0.0008522625,0.0020747248],"category_scores_gemma":[0.00040650024,0.0006897341,0.00047432946,0.00037043655,0.00079106924,0.00054031867,0.00065600354,0.0010539953,0.0008174151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002594691,0.00007118734,0.00080217764,0.000023101029,0.000007063197,0.00019362982,0.00003112508,0.00009913316,0.9969873,0.00030043215,0.000054647997,0.0011708724],"study_design_scores_gemma":[0.00011539876,0.0008074392,0.02376923,0.000022784014,0.00005347087,0.0016428351,0.0001178209,0.0026091589,0.96482855,0.00041543337,0.0055912887,0.00002659761],"about_ca_topic_score_codex":0.0010440914,"about_ca_topic_score_gemma":0.0015888241,"teacher_disagreement_score":0.0020747248,"about_ca_system_score_codex":0.0005667749,"about_ca_system_score_gemma":0.00040265464,"threshold_uncertainty_score":0.0069406033},"labels":[],"label_agreement":null},{"id":"W2067735292","doi":"10.1172/jci64151","title":"MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Birth, Development, and Health","field":"Medicine","cited_by":168,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Health and Medical Research Council; Medical Research Council; Société Francophone du Diabète; Fondation pour la Recherche Médicale; European Foundation for the Study of Diabetes; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Endocrinology; microRNA; Internal medicine; GPER; Biology; Insulin resistance; Estrogen receptor; Gene silencing; Insulin; Cell; Medicine; Gene; Genetics","score_opus":0.0802865116520196,"score_gpt":0.368948658995544,"score_spread":0.2886621473435244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067735292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891923,0.00434316,0.0036534935,0.00030154892,0.0000599655,0.000023262959,0.00009251182,0.000092471426,0.0022411798],"genre_scores_gemma":[0.9953538,0.0019827676,0.0015914574,0.00011083786,0.000023548339,0.00003136317,0.00006428607,0.000020386073,0.0008216188],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99986684,0.000038314603,0.000012035318,0.000024514798,0.000022130469,0.000036048616],"domain_scores_gemma":[0.99983525,0.00003939952,0.00007137442,0.000016597416,0.000011610268,0.000025722913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023665535,0.000293036,0.00018527944,0.0001966006,0.00013737206,0.00029546767,0.0001358555,0.00029600508,0.00063997443],"category_scores_gemma":[0.0004248605,0.00020718893,0.00017348706,0.00009201767,0.00029455134,0.00017281856,0.00028105165,0.00046691348,0.00017126866],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008234867,0.000032410735,0.0034584557,0.00005656668,0.000010578872,0.0009206471,0.00011586668,0.00012591982,0.9835524,0.00041921056,0.00013002244,0.010354496],"study_design_scores_gemma":[0.00009917418,0.0012688279,0.1687112,0.000080531594,0.0001340398,0.008045307,0.00035737504,0.0024518145,0.80308354,0.0017292317,0.013997784,0.000041280804],"about_ca_topic_score_codex":0.00018991632,"about_ca_topic_score_gemma":0.00024024055,"teacher_disagreement_score":0.00063997443,"about_ca_system_score_codex":0.00019439768,"about_ca_system_score_gemma":0.00021760377,"threshold_uncertainty_score":0.0021409392},"labels":[],"label_agreement":null},{"id":"W2067753785","doi":"10.1172/jci44339","title":"Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; Pfizer; National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Cancer Institute; National Institutes of Health; RSNA Research and Education Foundation; Covis Pharma; Radiological Society of North America; Harvard University; Harvard Catalyst; Cancer Research Institute","keywords":"Insulitis; Pancreas; Islet; Medicine; Type 1 diabetes; Inflammation; Magnetic resonance imaging; Diabetes mellitus; Pancreatic islets; Pathology; Type 2 diabetes; Immunology; Internal medicine; Endocrinology; Radiology","score_opus":0.013304576467184198,"score_gpt":0.29324893878754854,"score_spread":0.27994436232036435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067753785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872918,0.001894538,0.008546709,0.0002040743,0.000012950496,0.00002427746,0.000047639332,0.00006214495,0.001915825],"genre_scores_gemma":[0.9888482,0.0010893652,0.009168136,0.00014207466,0.000023418312,0.00003668675,0.0000575243,0.000010984266,0.0006235914],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99993014,0.00003033799,0.000003980465,0.000014466952,0.000011453122,0.000009712152],"domain_scores_gemma":[0.9999275,0.000026581232,0.000015573056,0.0000059024214,0.000007652241,0.0000167782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024296282,0.00015681585,0.0001928914,0.000287662,0.000078961646,0.00024461662,0.00010693222,0.00036273964,0.0006937952],"category_scores_gemma":[0.0003116793,0.000121920886,0.00008605332,0.00013165438,0.000103803715,0.00021054554,0.00017061409,0.00035528617,0.00010374801],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015999952,0.00015030097,0.02351723,0.00012612416,0.000021332504,0.0017005664,0.0001694469,0.0001932704,0.94404465,0.00020568291,0.0002779121,0.027993504],"study_design_scores_gemma":[0.00034937303,0.0031847644,0.24151573,0.00012033994,0.00022626098,0.02618528,0.00066759466,0.01889708,0.70031995,0.0011066792,0.007374326,0.000052624542],"about_ca_topic_score_codex":0.00013592768,"about_ca_topic_score_gemma":0.00016041147,"teacher_disagreement_score":0.0006937952,"about_ca_system_score_codex":0.00008664494,"about_ca_system_score_gemma":0.000054203392,"threshold_uncertainty_score":0.0023210049},"labels":[],"label_agreement":null},{"id":"W2068014330","doi":"10.1172/jci14661","title":"Putting the brakes on arthritis: can suppressors of cytokine signaling (SOCS) suppress rheumatoid arthritis?","year":2001,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Cytokine; Janus kinase; Suppressor of cytokine signalling; JAK-STAT signaling pathway; SOCS3; Suppressor of cytokine signaling 1; Biology; Cytokine receptor; Immunology; Src family kinase; stat; Signal transduction; Cancer research; Kinase; Immune system; Medicine; Tyrosine kinase; Cell biology; Suppressor; STAT3; Genetics; Cancer","score_opus":0.07611232099468855,"score_gpt":0.34822776013809104,"score_spread":0.27211543914340247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068014330","genre_codex":"review","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.045716003,0.90393996,0.0032511526,0.027807867,0.0067390604,0.00015263623,0.00041733505,0.0003210955,0.011654935],"genre_scores_gemma":[0.36320284,0.59355646,0.0025532143,0.021123165,0.0086048795,0.00029354283,0.0006917364,0.000058303427,0.009915836],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996805,0.00008747376,0.000023998049,0.000036394486,0.000082677085,0.00008893368],"domain_scores_gemma":[0.9996463,0.0000795584,0.00007898625,0.00002175968,0.00006661257,0.00010673762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010559567,0.00081317365,0.0010411965,0.0005978263,0.00032732176,0.0016282753,0.00075381354,0.0015841307,0.00362135],"category_scores_gemma":[0.0008787384,0.00026799616,0.000591641,0.00034982775,0.0013683784,0.0012876862,0.0005465934,0.003364938,0.0016378765],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005354947,0.0014297791,0.0019012538,0.0063545248,0.0005213133,0.0010008666,0.00043737135,0.002071296,0.0918171,0.021387205,0.08687315,0.7808512],"study_design_scores_gemma":[0.004236287,0.012571554,0.00751755,0.0022207545,0.0007824943,0.0021969697,0.0006245476,0.0027593004,0.032919675,0.0267312,0.90725553,0.00018419368],"about_ca_topic_score_codex":0.00029909806,"about_ca_topic_score_gemma":0.0011722015,"teacher_disagreement_score":0.00362135,"about_ca_system_score_codex":0.00035582087,"about_ca_system_score_gemma":0.00062447594,"threshold_uncertainty_score":0.012114584},"labels":[],"label_agreement":null},{"id":"W2068671129","doi":"10.1172/jci63528","title":"The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Deutsche Forschungsgemeinschaft; Canadian Institutes of Health Research; Terry Fox Foundation; Alexander von Humboldt-Stiftung","keywords":"RELB; Experimental autoimmune encephalomyelitis; Cell biology; Neuroinflammation; Biology; Regulator; Interleukin 17; Autoimmunity; Immunology; Cytokine; Transcription factor; Immune system; Inflammation; NFKB1","score_opus":0.039316574740532365,"score_gpt":0.3267949869912838,"score_spread":0.28747841225075144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068671129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99068147,0.005532281,0.0021325883,0.0001237505,0.000020645906,0.00002260785,0.00027580536,0.000061032708,0.0011498331],"genre_scores_gemma":[0.9963684,0.0017925625,0.00078759366,0.000026327561,0.000011401698,0.000013485432,0.00019528529,0.000014225725,0.0007906951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998559,0.000030208073,0.000013512798,0.000033575336,0.000025760684,0.00004110535],"domain_scores_gemma":[0.999778,0.000027770506,0.0001068517,0.000018914123,0.00002034968,0.0000480209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001493057,0.00050095073,0.00026316277,0.00023401933,0.00014261846,0.00046401194,0.00013879723,0.0002516312,0.0018967845],"category_scores_gemma":[0.00022034065,0.00013601454,0.00013690117,0.00014959557,0.00036074992,0.00032960583,0.00023606334,0.0007599312,0.0006224467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014773622,0.000016100787,0.0007208633,0.00003766471,0.0000024851336,0.000083835475,0.000014988661,0.000018773098,0.9977773,0.000056274548,0.000019736186,0.0011043148],"study_design_scores_gemma":[0.000031763786,0.00041332425,0.018623492,0.000029760311,0.000033465363,0.0026171885,0.00009300741,0.00046532453,0.9737562,0.0002010175,0.0037288729,0.0000065140225],"about_ca_topic_score_codex":0.0001552899,"about_ca_topic_score_gemma":0.00017174604,"teacher_disagreement_score":0.0018967845,"about_ca_system_score_codex":0.00022734448,"about_ca_system_score_gemma":0.00017131947,"threshold_uncertainty_score":0.006345451},"labels":[],"label_agreement":null},{"id":"W2068859282","doi":"10.1172/jci24685","title":"The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":437,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Michael Smith Health Research BC","keywords":"FOXP3; IL-2 receptor; In vitro; Transcription factor; Cell biology; Suppressor; Biology; Gene isoform; Ectopic expression; Immunology; Chemistry; Immune system; T cell; Gene; Genetics","score_opus":0.07476707422737831,"score_gpt":0.3548335584808393,"score_spread":0.280066484253461,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068859282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98053247,0.0120876925,0.0042300946,0.00027743317,0.000049439583,0.000032838423,0.00018056226,0.00006479927,0.0025447132],"genre_scores_gemma":[0.99504906,0.0018699385,0.0018540147,0.00008799912,0.000031456868,0.000015276022,0.00018976945,0.000010684334,0.0008918357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998615,0.00003858111,0.000011705096,0.000025677042,0.000033132936,0.000029398474],"domain_scores_gemma":[0.9998977,0.000035500172,0.00002121438,0.000014041882,0.000009049008,0.000022431506],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005926563,0.00017006283,0.00015011326,0.00020827573,0.00010306938,0.00029443088,0.00010466377,0.0002494189,0.00088940136],"category_scores_gemma":[0.00032492646,0.00007999854,0.00012222237,0.00008729681,0.00016027234,0.00015048473,0.00014119064,0.00022124377,0.00026205336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012010756,0.000043240205,0.0038730032,0.000075843986,0.000010310253,0.00044349476,0.000074310745,0.00018403561,0.964706,0.0004678673,0.00018084732,0.028739907],"study_design_scores_gemma":[0.00027482008,0.0013447447,0.040178254,0.00007498352,0.00009073457,0.00699066,0.00015221054,0.0021000418,0.92366356,0.0014003784,0.023707401,0.00002219491],"about_ca_topic_score_codex":0.00022772065,"about_ca_topic_score_gemma":0.00027384044,"teacher_disagreement_score":0.00088940136,"about_ca_system_score_codex":0.00015285447,"about_ca_system_score_gemma":0.00025615367,"threshold_uncertainty_score":0.0031342506},"labels":[],"label_agreement":null},{"id":"W2068996358","doi":"10.1172/jci70026","title":"A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":279,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Peking University; National Institute of Dental and Craniofacial Research; University of Ottawa","keywords":"Inhibitory postsynaptic potential; Glycine receptor; Neuroscience; Allodynia; Nociception; Neuropathic pain; Spinal cord; Excitatory postsynaptic potential; Neurotransmission; Medicine; Chemistry; Hyperalgesia; Biology; Glycine; Receptor; Internal medicine","score_opus":0.10812587266910419,"score_gpt":0.3856029535707906,"score_spread":0.27747708090168643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068996358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9717405,0.003215244,0.018414032,0.00038408578,0.00006272585,0.000070202936,0.00011451613,0.000400975,0.0055977283],"genre_scores_gemma":[0.99437404,0.0014153686,0.0027789408,0.00007042067,0.000011383814,0.000017673045,0.00004890203,0.000006404966,0.0012769486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999949,0.0000068364143,0.000003799917,0.000009733068,0.000016827516,0.000013877254],"domain_scores_gemma":[0.99996424,0.0000049505843,0.000011499218,0.000003857814,0.000006251617,0.000009310664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007163913,0.00042908147,0.00023620899,0.00019475204,0.00019612597,0.00031028583,0.00022598101,0.00024012374,0.00084841007],"category_scores_gemma":[0.00013621793,0.00011784096,0.00016949848,0.0000833697,0.00034079465,0.00029989643,0.00020374727,0.0004847883,0.00025138445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029786667,0.000041580523,0.0006733553,0.00009836635,0.000017586668,0.0003244234,0.00003630673,0.00042459808,0.98617154,0.001174558,0.00008803185,0.010651793],"study_design_scores_gemma":[0.00010280951,0.0017696855,0.014018997,0.000058923895,0.000101867794,0.0012566542,0.00008274001,0.006348627,0.96980536,0.001962927,0.0044688494,0.000022486143],"about_ca_topic_score_codex":0.0008429222,"about_ca_topic_score_gemma":0.0015341209,"teacher_disagreement_score":0.00084841007,"about_ca_system_score_codex":0.0004759786,"about_ca_system_score_gemma":0.0003666093,"threshold_uncertainty_score":0.0034534335},"labels":[],"label_agreement":null},{"id":"W2069938061","doi":"10.1172/jci35639","title":"Immunosuppression in islet transplantation","year":2008,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institutes of Health; Deutsche Forschungsgemeinschaft; Belgian American Educational Foundation","keywords":"Immunosuppression; Islet; Transplantation; Medicine; Immunology; Population; Immune tolerance; Immune system; CD8; Glucose homeostasis; Diabetes mellitus; Internal medicine; Endocrinology; Insulin resistance","score_opus":0.0942872400159028,"score_gpt":0.3717509028813602,"score_spread":0.2774636628654574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069938061","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.024941951,0.3197859,0.005169423,0.544097,0.0665698,0.00008684368,0.00003994449,0.00020623347,0.03910285],"genre_scores_gemma":[0.18017973,0.1863601,0.002985962,0.33991438,0.27929074,0.00017742705,0.000059182403,0.00005343402,0.010979017],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990343,0.000445262,0.0001007565,0.00006816082,0.00026730416,0.00008426971],"domain_scores_gemma":[0.99826956,0.0013294198,0.000120906196,0.000077687924,0.00009707611,0.000105301995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016183862,0.000707582,0.0009898088,0.0003881303,0.0010180741,0.0010889356,0.00078826025,0.007676405,0.001305986],"category_scores_gemma":[0.0036066487,0.0002518112,0.00055441726,0.00032632716,0.0017456316,0.0012714899,0.000546695,0.009890234,0.0013686233],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008770407,0.00048523763,0.00665373,0.0022565818,0.00013913956,0.24498807,0.00039281353,0.0009276374,0.008522036,0.033996582,0.35857615,0.34218484],"study_design_scores_gemma":[0.0004825992,0.0007302147,0.004745953,0.0016580286,0.00010459114,0.26299548,0.0002883726,0.0014265142,0.0034863297,0.031154536,0.692865,0.00006232006],"about_ca_topic_score_codex":0.00015733227,"about_ca_topic_score_gemma":0.00035159444,"teacher_disagreement_score":0.007676405,"about_ca_system_score_codex":0.0010141728,"about_ca_system_score_gemma":0.0003666259,"threshold_uncertainty_score":0.008558929},"labels":[],"label_agreement":null},{"id":"W2070414981","doi":"10.1172/jci68341","title":"Deep brain stimulation (DBS) at the interface of neurology and psychiatry","year":2013,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Movement Disorders","funders":"Parkinsonfonden; National Institute on Drug Abuse; National Parkinson Foundation","keywords":"Deep brain stimulation; Tourette syndrome; Neurology; Neuroscience; Medicine; Major depressive disorder; Psychiatry; Disease; Parkinson's disease; Psychology; Mood; Internal medicine","score_opus":0.1502683941708566,"score_gpt":0.46944260361026563,"score_spread":0.319174209439409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070414981","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026712962,0.9962753,0.00044887827,0.00032774883,0.00024553176,0.000009367027,0.000015594816,0.000012492472,0.0023978993],"genre_scores_gemma":[0.0013047466,0.99648166,0.0006612185,0.00019040749,0.00019310077,0.000011521291,0.00002523886,0.0000021916226,0.0011298999],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99986064,0.000025619222,0.000020524756,0.00002027262,0.000059185673,0.000013735481],"domain_scores_gemma":[0.999796,0.000096252996,0.000025226102,0.000006813,0.00005464747,0.000020977133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045575164,0.00070521235,0.0010726184,0.001880816,0.00022795831,0.00078385475,0.0005807132,0.0009117324,0.004190326],"category_scores_gemma":[0.00047670578,0.00016455063,0.00038836978,0.0016378281,0.00041894306,0.0009848094,0.0006166436,0.0011696668,0.0031247104],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004324682,0.00006484128,0.0001742172,0.008940855,0.000051279487,0.00027046356,0.0000343948,0.00015070816,0.0031182386,0.0025776983,0.013085838,0.9714884],"study_design_scores_gemma":[0.000035747944,0.00021057914,0.0021597664,0.0046844864,0.00012510919,0.005454889,0.00012851298,0.0001880167,0.0018756691,0.004161425,0.98094237,0.000033489494],"about_ca_topic_score_codex":0.0006504888,"about_ca_topic_score_gemma":0.0014856905,"teacher_disagreement_score":0.004190326,"about_ca_system_score_codex":0.000433703,"about_ca_system_score_gemma":0.0009511481,"threshold_uncertainty_score":0.014018059},"labels":[],"label_agreement":null},{"id":"W2071039886","doi":"10.1172/jci63563","title":"Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":223,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; University of Pennsylvania; Strong; American Heart Association","keywords":"Apolipoprotein B; Catabolism; Internal medicine; Endocrinology; Secretion; Lysosome; Biology; Intracellular; Chemistry; Cell biology; Cholesterol; Biochemistry; Enzyme; Metabolism; Medicine","score_opus":0.03360024377918306,"score_gpt":0.3120263134213961,"score_spread":0.278426069642213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071039886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958697,0.0017438902,0.0010162224,0.0001481494,0.000009836099,0.0000052383402,0.00015950126,0.0000563812,0.0009910996],"genre_scores_gemma":[0.9974496,0.0008832543,0.0005648457,0.000048952013,0.000008856683,0.000004802399,0.00012233063,0.000009761436,0.00090773427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999163,0.000024126814,0.000006218442,0.000018650426,0.000020805399,0.000013853859],"domain_scores_gemma":[0.9998796,0.000016549231,0.00005205975,0.000008049361,0.000015496147,0.000028167868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011786266,0.00021427475,0.00016464872,0.00025395898,0.00010139673,0.00029945243,0.000099405974,0.000190845,0.0007508912],"category_scores_gemma":[0.00016200595,0.00011700255,0.00011175844,0.00018261684,0.00016149067,0.0000779107,0.0001797508,0.00015365629,0.00016728771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020928318,0.000049048624,0.056493495,0.00014334278,0.00014972907,0.00070578506,0.0000815201,0.0004187083,0.91724265,0.0005353459,0.00054806424,0.021539465],"study_design_scores_gemma":[0.00013257533,0.00033128867,0.8273882,0.000025656671,0.00019441813,0.0028794254,0.00014044605,0.0033820833,0.15978844,0.0011038893,0.0046086563,0.000024865449],"about_ca_topic_score_codex":0.0009820019,"about_ca_topic_score_gemma":0.0011693515,"teacher_disagreement_score":0.0009820019,"about_ca_system_score_codex":0.00025686508,"about_ca_system_score_gemma":0.00012109534,"threshold_uncertainty_score":0.0025120378},"labels":[],"label_agreement":null},{"id":"W2072045863","doi":"10.1172/jci12627","title":"Generation of experimental allergic airways inflammation in the absence of draining lymph nodes","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Immunology; Ovalbumin; Spleen; Allergic inflammation; Lymph; Sensitization; Lymphatic system; Inflammation; Medicine; Splenocyte; Immunoglobulin E; Antigen; Pathology; Antibody","score_opus":0.15358021607135777,"score_gpt":0.4018668624508431,"score_spread":0.2482866463794853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072045863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946069,0.0016469369,0.0019083394,0.00010418281,0.00007854822,0.00022678317,0.00029245162,0.00010099178,0.001034807],"genre_scores_gemma":[0.99100655,0.001564524,0.004008634,0.00011236793,0.00007045553,0.00037149433,0.00075284555,0.000040482133,0.0020726388],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993383,0.00018432741,0.0000891135,0.00011964185,0.0001403524,0.00012829479],"domain_scores_gemma":[0.9994137,0.00011857762,0.00014725284,0.00013652547,0.000030633644,0.00015330414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006441121,0.0009716965,0.00065530586,0.00052623375,0.00035591162,0.00050614215,0.0005007672,0.0007007175,0.0014932994],"category_scores_gemma":[0.00038095802,0.00040912806,0.0004691433,0.00020873419,0.0007609461,0.00071649556,0.00040506935,0.0022839166,0.000533163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008691173,0.0006127655,0.0003564118,0.000105949555,0.000009732603,0.00021457537,0.00003367649,0.00010736809,0.9962424,0.00022619325,0.000045334873,0.0011765028],"study_design_scores_gemma":[0.0005412798,0.01225231,0.006085151,0.00005838417,0.00009260788,0.0017042026,0.00009162442,0.0009948564,0.97465456,0.00016929711,0.0033406753,0.000015035262],"about_ca_topic_score_codex":0.00020014204,"about_ca_topic_score_gemma":0.0005071718,"teacher_disagreement_score":0.0014932994,"about_ca_system_score_codex":0.00035723313,"about_ca_system_score_gemma":0.00038055057,"threshold_uncertainty_score":0.0049955845},"labels":[],"label_agreement":null},{"id":"W2072590237","doi":"10.1172/jci17220","title":"The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":203,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Furin; Proprotein Convertases; Angiogenesis; Proprotein convertase; Cell biology; Molecular biology; Chemistry; Cleavage (geology); Carcinogenesis; Biology; Cancer research; Biochemistry; Enzyme; Gene","score_opus":0.08073920457234184,"score_gpt":0.3712970140702853,"score_spread":0.29055780949794346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072590237","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98676634,0.0017198967,0.007442864,0.00007803543,0.000030044424,0.000066593435,0.0004337496,0.00014131496,0.0033212125],"genre_scores_gemma":[0.98771465,0.0008848012,0.006461166,0.000042487147,0.000009286504,0.000032814427,0.0008451476,0.000018304785,0.003991321],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991775,0.0000101752685,0.000004798789,0.000012430482,0.000026178757,0.000028652597],"domain_scores_gemma":[0.9999219,0.000013215674,0.000015528922,0.000008068455,0.000010448548,0.000030788287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009485436,0.00033410528,0.00013794159,0.00025805685,0.000123959,0.00024443291,0.00009183805,0.00017844852,0.0010900269],"category_scores_gemma":[0.00009120514,0.00008435291,0.00022833506,0.00013947666,0.00012291897,0.0001284278,0.00014805613,0.0004554318,0.00037234082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056875535,0.000016093587,0.00018553527,0.000016030033,0.0000032672915,0.000042539068,0.0000073250503,0.000049263475,0.9977088,0.00014865701,0.000041562133,0.0017241735],"study_design_scores_gemma":[0.000008211585,0.00011245887,0.0025586244,0.0000029333303,0.00000652508,0.00016672748,0.000009724631,0.00069975486,0.9942281,0.000052323372,0.002152717,0.0000018994754],"about_ca_topic_score_codex":0.0008906162,"about_ca_topic_score_gemma":0.00088620506,"teacher_disagreement_score":0.0010900269,"about_ca_system_score_codex":0.00037782895,"about_ca_system_score_gemma":0.00026975447,"threshold_uncertainty_score":0.003646493},"labels":[],"label_agreement":null},{"id":"W2072691337","doi":"10.1172/jci34584","title":"Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":506,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Cancer Research UK","keywords":"Antigen; CTL*; C-type lectin; Biology; Cross-presentation; Immunology; CD8; Epitope; Priming (agriculture); Dendritic cell; T cell; Immune system; Cancer research; MHC class I","score_opus":0.08076732815346165,"score_gpt":0.3413902789587154,"score_spread":0.2606229508052537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072691337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9677163,0.0077032372,0.015709598,0.0010164307,0.000195234,0.00040317696,0.00072255085,0.0006556918,0.0058778385],"genre_scores_gemma":[0.9737048,0.0037957432,0.012169173,0.00030903748,0.000051495932,0.0003275549,0.00088838657,0.00004113091,0.008712514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986947,0.00002479958,0.000008308926,0.00003431447,0.000023505669,0.00003956006],"domain_scores_gemma":[0.9999441,0.0000070758933,0.000020398571,0.00000835026,0.000004199683,0.000015962614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017588152,0.0006054089,0.0002836477,0.00033003124,0.00013376535,0.00026239513,0.00027050005,0.00052963744,0.0011164806],"category_scores_gemma":[0.000070905306,0.0001445999,0.0001721835,0.00014626718,0.00035709096,0.00026747107,0.0001672137,0.0010113028,0.0003867943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032507672,0.00022172788,0.000121906094,0.000054896787,0.0000048967854,0.000051289713,0.000011273261,0.00007895147,0.9936469,0.00040763296,0.0001670394,0.0049084],"study_design_scores_gemma":[0.00022836945,0.0034039153,0.0018726517,0.000020789914,0.000032704258,0.00086126826,0.000014618048,0.0014190503,0.97496766,0.00024200644,0.016929781,0.0000072236476],"about_ca_topic_score_codex":0.00026936716,"about_ca_topic_score_gemma":0.00041389253,"teacher_disagreement_score":0.0011164806,"about_ca_system_score_codex":0.00033023395,"about_ca_system_score_gemma":0.00030141906,"threshold_uncertainty_score":0.0037350059},"labels":[],"label_agreement":null},{"id":"W2072693941","doi":"10.1172/jci64398","title":"GSK-3α is a central regulator of age-related pathologies in mice","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Heart, Lung, and Blood Institute; National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research","keywords":"mTORC1; Autophagy; Skeletal muscle; Sarcopenia; Biology; GSK-3; Cell biology; PI3K/AKT/mTOR pathway; Regulator; Senescence; Muscle hypertrophy; Kinase; Glycogen synthase; Endocrinology; GSK3B; Proteostasis; Internal medicine; Signal transduction; Phosphorylation; Medicine; Biochemistry; Gene; Apoptosis","score_opus":0.03529901623741275,"score_gpt":0.3284804727403359,"score_spread":0.29318145650292315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072693941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9301933,0.012490965,0.0300162,0.001821459,0.0005564317,0.00029730148,0.009593094,0.0037921993,0.011239007],"genre_scores_gemma":[0.94846827,0.0077332426,0.01703225,0.0004930363,0.00009907181,0.00066970265,0.00626295,0.0005021608,0.018739397],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99965346,0.00006036191,0.000059675745,0.000101409096,0.00007763524,0.000047520876],"domain_scores_gemma":[0.9996629,0.00002740889,0.0001516918,0.000039350372,0.000024284067,0.00009439845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039241512,0.0012817438,0.000548537,0.0017515003,0.0004313214,0.00060496875,0.0003945179,0.00080158276,0.0048943153],"category_scores_gemma":[0.00019866892,0.00067556434,0.0007634356,0.0006396591,0.00078865886,0.00049365393,0.0004886497,0.0014967888,0.0018157131],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005715227,0.0001064126,0.0005697048,0.00013949467,0.0000331296,0.00029478825,0.00004016044,0.00011843682,0.99229574,0.0007091559,0.00044849172,0.004672981],"study_design_scores_gemma":[0.0004904073,0.0013702362,0.02551682,0.00020267884,0.000231034,0.0037421552,0.00012404038,0.0030884254,0.924596,0.0020853386,0.038506474,0.000046519803],"about_ca_topic_score_codex":0.0004950926,"about_ca_topic_score_gemma":0.00090778887,"teacher_disagreement_score":0.0048943153,"about_ca_system_score_codex":0.0005830923,"about_ca_system_score_gemma":0.00058909255,"threshold_uncertainty_score":0.016373098},"labels":[],"label_agreement":null},{"id":"W2072855828","doi":"10.1172/jci39457","title":"Integrin-linked kinase: both Jekyll and Hyde in rhabdomyosarcoma","year":2009,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Rhabdomyosarcoma; Embryonal rhabdomyosarcoma; Alveolar rhabdomyosarcoma; Cancer research; Integrin-linked kinase; Integrin; Oncogene; Suppressor; Biology; Kinase; Medicine; Sarcoma; Protein kinase A; Internal medicine; Pathology; Cancer; Cell biology; Receptor; Cell cycle","score_opus":0.09747765355614357,"score_gpt":0.38401387234186574,"score_spread":0.28653621878572216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072855828","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06960015,0.024450867,0.0016842138,0.8452352,0.02320226,0.00009033247,0.00009772747,0.00019903519,0.03544024],"genre_scores_gemma":[0.46923238,0.021321008,0.0027837043,0.33669242,0.11599679,0.00016183412,0.0001467608,0.00006270363,0.053602453],"study_design_codex":"case_report","study_design_gemma":"not_applicable","domain_scores_codex":[0.99958724,0.0001201924,0.00005010618,0.000059630147,0.00010968427,0.000073243726],"domain_scores_gemma":[0.9994709,0.0003008361,0.000058386297,0.000035315945,0.000057771267,0.00007679918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005191497,0.0004709963,0.00062981324,0.00031986588,0.0007215191,0.00076809747,0.00052493246,0.008707576,0.0019673111],"category_scores_gemma":[0.0026462285,0.00027450413,0.00040214715,0.00026160528,0.0008861814,0.0012124042,0.00027480396,0.0042494326,0.0017347207],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009580848,0.00035991348,0.01519926,0.00057896785,0.000089843925,0.46163094,0.00047372514,0.0005921943,0.0110099325,0.011421794,0.42290056,0.07478481],"study_design_scores_gemma":[0.0005912458,0.00043274453,0.015261403,0.00032831702,0.00011608615,0.5181713,0.00048345618,0.0033251708,0.004297413,0.011991085,0.44493705,0.00006465778],"about_ca_topic_score_codex":0.0005601819,"about_ca_topic_score_gemma":0.0010454656,"teacher_disagreement_score":0.008707576,"about_ca_system_score_codex":0.0012702201,"about_ca_system_score_gemma":0.00034242935,"threshold_uncertainty_score":0.00921613},"labels":[],"label_agreement":null},{"id":"W2073256068","doi":"10.1172/jci16551","title":"Hot new therapy for sepsis and the acute respiratory distress syndrome","year":2002,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"ARDS; Intensive care medicine; Sepsis; Acute respiratory distress; Medicine; Respiratory distress; Translational research; Basic research; Immunology; Lung; Internal medicine; Pathology; Surgery","score_opus":0.15333942944909348,"score_gpt":0.39138973498160906,"score_spread":0.23805030553251558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073256068","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028294711,0.064403415,0.00041963824,0.8709694,0.050550766,0.00005563231,0.000035824392,0.000063162246,0.010672707],"genre_scores_gemma":[0.030336961,0.055673096,0.0008057681,0.7384177,0.14977343,0.00016533217,0.000054771743,0.000028869894,0.024744112],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992028,0.00029682205,0.000076205644,0.00007832576,0.00026210572,0.00008383077],"domain_scores_gemma":[0.9988166,0.000711843,0.000088962894,0.000035610974,0.0001724283,0.0001745677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00093339564,0.00069905363,0.0009798841,0.000482141,0.0012660398,0.001123937,0.00062836404,0.011084406,0.004063764],"category_scores_gemma":[0.0051581156,0.00026525685,0.0005075415,0.0004036739,0.0013311261,0.0018832164,0.0005620021,0.009334052,0.0033235524],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045179506,0.00015837356,0.0017606588,0.00061080785,0.000052742347,0.025711926,0.00029821732,0.00020533192,0.0016496476,0.007414461,0.8412859,0.12040003],"study_design_scores_gemma":[0.00040329288,0.0003490833,0.0023403768,0.0004926562,0.000039972474,0.024363298,0.00020186145,0.00033815153,0.00046801355,0.0064067557,0.9645627,0.00003379336],"about_ca_topic_score_codex":0.00042812765,"about_ca_topic_score_gemma":0.0012234971,"teacher_disagreement_score":0.011084406,"about_ca_system_score_codex":0.0012146444,"about_ca_system_score_gemma":0.0007451657,"threshold_uncertainty_score":0.013594627},"labels":[],"label_agreement":null},{"id":"W2073640180","doi":"10.1172/jci37787","title":"Cardiac troponin T mutations promote life-threatening arrhythmias","year":2008,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Myofilament; Mutation; Sudden cardiac death; Internal medicine; Cardiology; Troponin; Medicine; Sudden death; Sarcomere; Myocyte; Biology; Genetics; Gene","score_opus":0.10812122636932668,"score_gpt":0.37155054070071053,"score_spread":0.26342931433138383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073640180","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1153293,0.015753048,0.0013121271,0.76052916,0.015754238,0.00015596604,0.00020294297,0.00053087383,0.09043229],"genre_scores_gemma":[0.4875559,0.013354731,0.001310499,0.37254164,0.09613259,0.00011532881,0.00012461435,0.00010015288,0.028764574],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993813,0.00028106658,0.00005214354,0.000067498826,0.0001205009,0.000097441945],"domain_scores_gemma":[0.99774337,0.0014348469,0.00020033089,0.000113501934,0.0002685542,0.00023939705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007954722,0.00066720095,0.0008866134,0.00041086794,0.0010710688,0.0009770972,0.0004401562,0.009914363,0.0050710794],"category_scores_gemma":[0.008484609,0.00030726404,0.00037596832,0.00035297964,0.0010287194,0.0009702718,0.00042639967,0.0048850975,0.0037315928],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010591373,0.00038978108,0.036486927,0.0003726583,0.00006641063,0.24567941,0.0007581486,0.00040029045,0.010411633,0.0097506065,0.62208194,0.07254306],"study_design_scores_gemma":[0.0017396166,0.0012156885,0.070547275,0.0009058703,0.00016880997,0.45815843,0.0012870211,0.0042063347,0.0053921067,0.027169798,0.42904946,0.00015965819],"about_ca_topic_score_codex":0.0004374232,"about_ca_topic_score_gemma":0.000916939,"teacher_disagreement_score":0.009914363,"about_ca_system_score_codex":0.0007865296,"about_ca_system_score_gemma":0.00038366084,"threshold_uncertainty_score":0.016964436},"labels":[],"label_agreement":null},{"id":"W2076843567","doi":"10.1172/jci80743","title":"Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":270,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"FP7 Health; Biotechnology and Biological Sciences Research Council; Medical Research Council; Directorate for Biological Sciences; Rosetrees Trust; University College London Hospitals NHS Foundation Trust; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Wellcome Trust; Academy of Medical Sciences; CHDI Foundation; European Huntington's Disease Network; National Institute for Health and Care Research","keywords":"Huntingtin; Huntington's disease; Cerebrospinal fluid; Huntingtin Protein; Mutant; Disease; Medicine; Biology; Pathology; Genetics; Gene","score_opus":0.14522328702958304,"score_gpt":0.3666846870905437,"score_spread":0.22146140006096066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076843567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967001,0.000910397,0.0015082904,0.000029026347,0.000022116285,0.000024278661,0.00036960465,0.00006689089,0.00036922257],"genre_scores_gemma":[0.995138,0.00030558943,0.0035252734,0.00007384277,0.000025237854,0.000026335805,0.00068322325,0.00000856853,0.00021394785],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99968255,0.000045069097,0.00005197781,0.00007596107,0.000115688475,0.000028755425],"domain_scores_gemma":[0.99951136,0.0001432045,0.00010869558,0.000026874503,0.00014415722,0.00006569511],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004524405,0.00043521862,0.0002966249,0.0012445434,0.0002737757,0.0005078476,0.000166246,0.00042328855,0.00042621983],"category_scores_gemma":[0.0011696251,0.000121685334,0.00015797038,0.0003238808,0.00022427668,0.0001493087,0.00023126599,0.00027397546,0.00019286491],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010884503,0.00019412035,0.46284112,0.00022314112,0.0001853062,0.0018900567,0.0007203637,0.00026529832,0.50033426,0.00009058896,0.0006303524,0.03153694],"study_design_scores_gemma":[0.00006132554,0.0015876385,0.7489626,0.00009077401,0.0002063045,0.010695395,0.000438672,0.0026931039,0.23179533,0.00019458312,0.003236357,0.00003803565],"about_ca_topic_score_codex":0.0006709286,"about_ca_topic_score_gemma":0.00070368504,"teacher_disagreement_score":0.0012445434,"about_ca_system_score_codex":0.00020768438,"about_ca_system_score_gemma":0.00014163442,"threshold_uncertainty_score":0.0023927689},"labels":[],"label_agreement":null},{"id":"W2077523827","doi":"10.1172/jci29906","title":"Myeloid suppressor cells regulate the adaptive immune response to cancer","year":2006,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Arginase; Immune system; Myeloid-derived Suppressor Cell; Inflammation; Biology; Tumor microenvironment; Cancer research; Immunology; Population; Myeloid; Suppressor; Cell biology; Mesenchymal stem cell; Effector; Cancer; Medicine; Arginine; Biochemistry","score_opus":0.05288981135810948,"score_gpt":0.3350882654232567,"score_spread":0.2821984540651472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077523827","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06806233,0.10482886,0.0031522363,0.7438276,0.033173397,0.00023827414,0.00014258875,0.0004927625,0.046081964],"genre_scores_gemma":[0.47799218,0.08104536,0.0034727042,0.26688388,0.12963763,0.00025965224,0.00012635037,0.00007831332,0.040503975],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99967337,0.00013475517,0.000026530415,0.00003144429,0.000088435736,0.000045432735],"domain_scores_gemma":[0.99958795,0.00022800891,0.000043719006,0.00002351378,0.0000665568,0.00005018847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052698265,0.00046108186,0.00052188046,0.00027712932,0.00048678895,0.00069411297,0.00041288824,0.0035088467,0.002122942],"category_scores_gemma":[0.0016242579,0.00014941965,0.00024312297,0.00013333964,0.0010491112,0.0007054953,0.0003307948,0.0040335082,0.0015161623],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015263892,0.00045576366,0.008512537,0.0008362703,0.000071503215,0.04184874,0.000682988,0.0007777113,0.031905245,0.027118115,0.63158816,0.2546766],"study_design_scores_gemma":[0.00068144884,0.0006000451,0.0072175297,0.0002590098,0.000051266263,0.040572107,0.00027383407,0.002127873,0.009261651,0.015424636,0.9234946,0.000036156973],"about_ca_topic_score_codex":0.0001915056,"about_ca_topic_score_gemma":0.00034116508,"teacher_disagreement_score":0.0035088467,"about_ca_system_score_codex":0.00072417397,"about_ca_system_score_gemma":0.00030298726,"threshold_uncertainty_score":0.007101953},"labels":[],"label_agreement":null},{"id":"W2077789139","doi":"10.1172/jci33402","title":"Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":214,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; University College London","keywords":"Cytotoxic T cell; Interleukin-7 receptor; CD8; Biology; Immunology; Immune system; Antigen; Virology; T cell; IL-2 receptor; In vitro","score_opus":0.08110029745873976,"score_gpt":0.34393435699273883,"score_spread":0.2628340595339991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077789139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99946624,0.00017983356,0.00013762752,0.00001965747,0.0000031133497,0.000007706305,0.000021472382,0.000008911881,0.00015552272],"genre_scores_gemma":[0.99960774,0.000059826867,0.00012239937,0.000025440268,0.000006198597,0.000008953628,0.00005730046,0.000002508217,0.000109602865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998996,0.000024966752,0.000010957847,0.000027881259,0.000016343547,0.000020174219],"domain_scores_gemma":[0.99983895,0.000035519148,0.000043363118,0.00001238748,0.000010661834,0.000059171067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000210388,0.00022160458,0.0003517614,0.00033068666,0.0002236813,0.0002864324,0.0001476915,0.0002592336,0.0006963026],"category_scores_gemma":[0.00048340007,0.00016111905,0.00013977115,0.00013268011,0.00023180351,0.00020131066,0.00022509247,0.0003556642,0.00015004142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008399316,0.000829199,0.24309258,0.00016201843,0.00009649895,0.0071107605,0.0007032879,0.00067601295,0.7039047,0.00038498885,0.00051257416,0.034128007],"study_design_scores_gemma":[0.00057644694,0.013442782,0.8301102,0.00005124529,0.00021664929,0.04244184,0.0006001704,0.0053348863,0.10209545,0.00053982536,0.004555018,0.000035614714],"about_ca_topic_score_codex":0.00017508923,"about_ca_topic_score_gemma":0.00015483599,"teacher_disagreement_score":0.0006963026,"about_ca_system_score_codex":0.00016632654,"about_ca_system_score_gemma":0.0001270406,"threshold_uncertainty_score":0.0023293495},"labels":[],"label_agreement":null},{"id":"W2077951355","doi":"10.1172/jci64081","title":"GSK3β mediates muscle pathology in myotonic dystrophy","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute on Aging; Medical Center, University of Rochester","keywords":"Myotonic dystrophy; Myotonia; Skeletal muscle; Biology; Muscle weakness; Muscular dystrophy; Cell biology; Internal medicine; Endocrinology; Genetics; Biochemistry; Medicine","score_opus":0.13139434702508557,"score_gpt":0.38660658953995153,"score_spread":0.25521224251486596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077951355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97950613,0.013783877,0.0015763757,0.00044671836,0.00011363876,0.00004484505,0.0003602975,0.00020191584,0.0039662374],"genre_scores_gemma":[0.99364555,0.004017065,0.0003165022,0.00012681773,0.000026856058,0.000035987894,0.00031965453,0.000013424206,0.0014980893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992883,0.000016195367,0.0000073803662,0.000014576004,0.000014451957,0.000018546878],"domain_scores_gemma":[0.99993324,0.000006362969,0.000028291313,0.0000056158683,0.000004139231,0.000022363265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015893842,0.0005806911,0.00036240276,0.00022421233,0.00019631418,0.00023873056,0.00015825307,0.00024539334,0.0016321501],"category_scores_gemma":[0.00011084674,0.00019085774,0.00024373892,0.00013429408,0.00029902192,0.000116822164,0.00026572388,0.0005177176,0.0005995639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00070170214,0.00009519328,0.0016201782,0.00021103666,0.000040290615,0.0007064877,0.000036193444,0.00022630201,0.9904694,0.0005080663,0.00052547496,0.0048596933],"study_design_scores_gemma":[0.0007900075,0.002201603,0.112553775,0.00015330032,0.00021055149,0.0068500084,0.00016306802,0.0025068275,0.8560683,0.0017963478,0.016672362,0.000033915367],"about_ca_topic_score_codex":0.00037429397,"about_ca_topic_score_gemma":0.000682117,"teacher_disagreement_score":0.0016321501,"about_ca_system_score_codex":0.0003334933,"about_ca_system_score_gemma":0.00016854474,"threshold_uncertainty_score":0.0054600835},"labels":[],"label_agreement":null},{"id":"W2077986249","doi":"10.1172/jci20430","title":"Quorum sensing and biofilm formation in Streptococcal infections","year":2003,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":291,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research","keywords":"Quorum sensing; Biofilm; Virulence; Histidine kinase; Microbiology; Response regulator; Regulator; Biology; Streptococcus; Bacteria; Bacterial protein; Histidine; Gene; Genetics; Amino acid","score_opus":0.18355946614448604,"score_gpt":0.4609394692594772,"score_spread":0.27738000311499117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077986249","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009128404,0.9990164,0.00007580787,0.00010762742,0.00011784148,0.0000029380446,0.000004807852,0.000003981875,0.0005792727],"genre_scores_gemma":[0.0006449429,0.9984658,0.0001225181,0.00009194893,0.00015742095,0.0000045343136,0.000014186354,7.0212775e-7,0.0004980815],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997886,0.000039733426,0.00002823558,0.000028827866,0.00009606906,0.00001857178],"domain_scores_gemma":[0.999741,0.000098846576,0.000042103246,0.000007954381,0.00007232645,0.000037779566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005729421,0.0009944163,0.001885444,0.0023148837,0.000361639,0.0009175382,0.0010408548,0.0015774694,0.0030668552],"category_scores_gemma":[0.00055870437,0.00030770025,0.00042295703,0.002233235,0.00062257785,0.0013512005,0.00056030124,0.0015428102,0.0028525451],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001289493,0.00012226873,0.00028438476,0.0145769,0.000068319154,0.00051019946,0.00009307314,0.00035607675,0.0033801654,0.003122151,0.025290938,0.95206666],"study_design_scores_gemma":[0.000050068942,0.00018627636,0.0021039194,0.0036708354,0.00008275586,0.003730727,0.00011073725,0.00011774291,0.00087297853,0.003164698,0.985881,0.000028253096],"about_ca_topic_score_codex":0.0011394292,"about_ca_topic_score_gemma":0.00188125,"teacher_disagreement_score":0.0030668552,"about_ca_system_score_codex":0.0006376256,"about_ca_system_score_gemma":0.0008016981,"threshold_uncertainty_score":0.010259688},"labels":[],"label_agreement":null},{"id":"W2079857524","doi":"10.1172/jci45450","title":"Integral role of integrins in Th17 development","year":2010,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; Louisiana State University","keywords":"Integrin; Autoimmunity; Immunology; T cell; Cell biology; Biology; Cell; Immune system; Genetics","score_opus":0.04766025678134944,"score_gpt":0.31164533453961546,"score_spread":0.263985077758266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079857524","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023691174,0.03782828,0.0012990491,0.8623448,0.032208253,0.00006543694,0.00015180196,0.00017052324,0.0422407],"genre_scores_gemma":[0.37283176,0.049340587,0.0026812784,0.37503168,0.15266924,0.00022998593,0.00015169759,0.00006176631,0.047002073],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940383,0.00022773181,0.00005354485,0.000055806056,0.00016125366,0.00009782656],"domain_scores_gemma":[0.9989932,0.0005416557,0.000098174045,0.00008667425,0.00013495804,0.00014538478],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007372951,0.0005088496,0.0005096928,0.00022884484,0.000828946,0.0011580228,0.0004458104,0.008487883,0.004653248],"category_scores_gemma":[0.0024428733,0.00025193102,0.00030000223,0.00016714053,0.0010617226,0.00087296625,0.00041852568,0.006199209,0.0027295842],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013682855,0.00025913212,0.003579331,0.0006061409,0.00005216172,0.037832413,0.00031572126,0.0004534137,0.027213247,0.022481505,0.79298866,0.11284999],"study_design_scores_gemma":[0.00049975485,0.00036725643,0.005563155,0.00034787296,0.000039248585,0.03223417,0.0003229007,0.0020224934,0.007911431,0.021892605,0.92874885,0.00005034286],"about_ca_topic_score_codex":0.0004023575,"about_ca_topic_score_gemma":0.0007103071,"teacher_disagreement_score":0.008487883,"about_ca_system_score_codex":0.0013733401,"about_ca_system_score_gemma":0.00054264977,"threshold_uncertainty_score":0.015566647},"labels":[],"label_agreement":null},{"id":"W2079858542","doi":"10.1172/jci44539","title":"CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":170,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; York University; University of Pennsylvania; Florida Department of Health; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Downregulation and upregulation; Biology; Reverse transcriptase; Viral replication; Virology; Immune system; Cancer research; Immunology; Gene; Virus; RNA; Genetics","score_opus":0.06064627039567337,"score_gpt":0.330316308847886,"score_spread":0.2696700384522126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079858542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99729854,0.0006803524,0.0007374932,0.000035736957,0.000011158751,0.00003343823,0.00007399089,0.000034548244,0.001094696],"genre_scores_gemma":[0.996912,0.00037646547,0.00061599916,0.00007836262,0.00006252965,0.000039063387,0.00026879885,0.0000134570255,0.0016333604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998919,0.000012943058,0.000007992442,0.00001799768,0.000022620827,0.000046523674],"domain_scores_gemma":[0.99980587,0.00004050613,0.000041775394,0.000024444484,0.000018857914,0.00006854435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017059814,0.00026664487,0.00025458785,0.0004201919,0.00025321115,0.00061204453,0.00021044277,0.00023854467,0.002549418],"category_scores_gemma":[0.00033410272,0.00011619734,0.00013133152,0.00016348154,0.0001821829,0.0002885624,0.000303785,0.00039277834,0.00036539332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009979295,0.00021146837,0.0070612757,0.00006868418,0.000021454844,0.00043060872,0.00014723137,0.00017376411,0.96704626,0.00022143738,0.00028241787,0.023337428],"study_design_scores_gemma":[0.0008506267,0.012086771,0.2172851,0.00008627693,0.000304916,0.011677856,0.0008117952,0.0046150163,0.7267895,0.0026910848,0.022730077,0.00007105094],"about_ca_topic_score_codex":0.00014562508,"about_ca_topic_score_gemma":0.00022888239,"teacher_disagreement_score":0.002549418,"about_ca_system_score_codex":0.00011874018,"about_ca_system_score_gemma":0.00009596506,"threshold_uncertainty_score":0.00852865},"labels":[],"label_agreement":null},{"id":"W2080072974","doi":"10.1172/jci45263","title":"Which species are in your feces?","year":2010,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Enterococcus faecium; Feces; Flora (microbiology); Antibiotics; Enterococcus; Biology; Vancomycin-resistant Enterococcus; Vancomycin; Medicine; Intensive care medicine; Microbiology; Bacteria; Immunology; Staphylococcus aureus","score_opus":0.0951756758891416,"score_gpt":0.38354397405892326,"score_spread":0.28836829816978166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080072974","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0058731125,0.008403243,0.0009015222,0.95133644,0.02004995,0.000026890644,0.00013366491,0.00012951072,0.013145673],"genre_scores_gemma":[0.057062566,0.011835383,0.0018920229,0.87029004,0.035045367,0.000040639166,0.00011671738,0.00006962312,0.023647696],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99951315,0.00015650279,0.00005929638,0.00008072132,0.000103424376,0.00008685575],"domain_scores_gemma":[0.99875236,0.00047212077,0.00015060887,0.00007444497,0.00032518644,0.00022534955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057006784,0.00047409965,0.00084532273,0.00037294332,0.0011206303,0.0012785911,0.0005206887,0.0077676107,0.008942589],"category_scores_gemma":[0.005224166,0.00023964481,0.0005103912,0.00029485984,0.0009351609,0.0019733168,0.00040091958,0.0077173794,0.007140128],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003118666,0.00008395241,0.006896507,0.00024404196,0.00004126625,0.025616594,0.00031839454,0.00008429072,0.0016587351,0.0037186004,0.8875553,0.07347054],"study_design_scores_gemma":[0.00014845154,0.00018334047,0.0056126155,0.0007227244,0.000074697826,0.10129253,0.001690537,0.00063505414,0.0014862253,0.014490173,0.87358946,0.000074270494],"about_ca_topic_score_codex":0.0017231256,"about_ca_topic_score_gemma":0.0021208287,"teacher_disagreement_score":0.008942589,"about_ca_system_score_codex":0.0010671167,"about_ca_system_score_gemma":0.00042512527,"threshold_uncertainty_score":0.02991587},"labels":[],"label_agreement":null},{"id":"W2080118521","doi":"10.1172/jci57755","title":"In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; State Government of Victoria; National Health and Medical Research Council; University of California, San Diego; National Institutes of Health; National Heart, Lung, and Blood Institute; Australian Government","keywords":"Zebrafish; Epitope; Oxidative stress; In vivo; Heat shock protein; Malondialdehyde; Green fluorescent protein; Monoclonal antibody; Transgene; Antibody; Chemistry; Biology; Molecular biology; Biochemistry; Cell biology; Immunology; Gene","score_opus":0.12942036466136436,"score_gpt":0.36444829743237506,"score_spread":0.2350279327710107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080118521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96881527,0.0019946066,0.022208966,0.00041520636,0.00009709035,0.0001568941,0.0014312671,0.00038728217,0.004493473],"genre_scores_gemma":[0.9532087,0.0022390268,0.028579695,0.00018989202,0.000023711626,0.00035464816,0.0008618739,0.00012777997,0.014414709],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998826,0.000013218217,0.000010586672,0.00003826792,0.000023449644,0.000031793308],"domain_scores_gemma":[0.9998957,0.000014469489,0.000031557858,0.000011401966,0.000018903347,0.000027910784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029094535,0.0005072772,0.00024632443,0.0004766892,0.00023568618,0.00020380771,0.00030260478,0.00049933867,0.0012992393],"category_scores_gemma":[0.00011625309,0.00028747995,0.00025837935,0.00013275958,0.00037629873,0.00021780739,0.0002558488,0.0007231616,0.00043063387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003201931,0.000009601635,0.00007009191,0.000018842218,0.0000013167852,0.00003278085,0.000017759587,0.00002132041,0.9993635,0.000075792916,0.000023712364,0.00033331144],"study_design_scores_gemma":[0.000035603884,0.00029087588,0.004804158,0.000016153475,0.000018494547,0.00024846313,0.000043197917,0.0013379449,0.99134266,0.0001066697,0.0017469497,0.00000888191],"about_ca_topic_score_codex":0.0029766567,"about_ca_topic_score_gemma":0.004424016,"teacher_disagreement_score":0.0029766567,"about_ca_system_score_codex":0.0005311458,"about_ca_system_score_gemma":0.00033774946,"threshold_uncertainty_score":0.0059186816},"labels":[],"label_agreement":null},{"id":"W2080629063","doi":"10.1172/jci63765","title":"Compromised genomic integrity impedes muscle growth after Atrx inactivation","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Ottawa; McMaster University Medical Centre; Ottawa Hospital","funders":"Canadian Institutes of Health Research; Ottawa Hospital Research Institute","keywords":"ATRX; Biology; Skeletal muscle; Cell biology; Chromatin; Genetics; Anatomy; Mutation; Gene","score_opus":0.05117976661273109,"score_gpt":0.3287129231598622,"score_spread":0.2775331565471311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080629063","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99460137,0.0011059522,0.0029129277,0.000067399305,0.000021256365,0.00001818127,0.00019307545,0.00012320046,0.000956656],"genre_scores_gemma":[0.99590033,0.00069764437,0.0012255389,0.00003472811,0.0000068715267,0.00001992334,0.00030756497,0.0000320267,0.0017753738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999846,0.000026340102,0.000019718174,0.000043226755,0.00004164215,0.000023192757],"domain_scores_gemma":[0.9997898,0.00006156154,0.000070979986,0.000024122288,0.0000110193905,0.000042552816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014781872,0.00031539932,0.00025954994,0.00030916347,0.00011972945,0.00022190713,0.00022800591,0.00033417408,0.0014939992],"category_scores_gemma":[0.00021349837,0.00022063687,0.00019123936,0.00009644769,0.00033256528,0.00023215343,0.00039542382,0.0006004866,0.00034599507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044199085,0.0000128078655,0.00021021151,0.000016405931,0.00000472745,0.00015566165,0.000011109577,0.000043144217,0.99876523,0.00007865209,0.000015681993,0.00064217456],"study_design_scores_gemma":[0.000015654576,0.00034698372,0.0087331,0.000011257603,0.000017860926,0.001684924,0.00003280084,0.00080480566,0.98690075,0.00008532055,0.0013625001,0.0000040592977],"about_ca_topic_score_codex":0.00036193078,"about_ca_topic_score_gemma":0.000683573,"teacher_disagreement_score":0.0014939992,"about_ca_system_score_codex":0.00014890548,"about_ca_system_score_gemma":0.00014131902,"threshold_uncertainty_score":0.004997909},"labels":[],"label_agreement":null},{"id":"W2080643168","doi":"10.1172/jci15952","title":"The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":292,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada; Montreal Children's Hospital","funders":"","keywords":"Osteogenesis imperfecta; Cancellous bone; Resorption; Bone remodeling; Cortical bone; Bone resorption; Biopsy; Medicine; Endocrinology; Internal medicine; Bone biopsy; Bone tissue; Bone histomorphometry; Chemistry; Osteoporosis; Anatomy; Trabecular bone","score_opus":0.020012068377054014,"score_gpt":0.3061488085369086,"score_spread":0.28613674015985463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080643168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9994728,0.00037639207,0.000032886328,0.000013117256,0.0000010864402,0.0000024489473,0.000017512231,0.000002316919,0.00008143808],"genre_scores_gemma":[0.9994085,0.0002615521,0.00017877652,0.00001897744,0.0000043889418,0.0000070266174,0.00005537689,0.0000016451108,0.00006389542],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99978286,0.00008463225,0.000016097449,0.000025983223,0.00004621782,0.000044204895],"domain_scores_gemma":[0.99960023,0.0001374732,0.00016537502,0.000014843707,0.000016015962,0.0000661074],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023481587,0.00019424502,0.0003199958,0.00023440296,0.00017115977,0.00017619021,0.00013228685,0.00026036112,0.00027859348],"category_scores_gemma":[0.0010889916,0.00017095475,0.00019852766,0.00017486601,0.00043231135,0.000121803176,0.00016023536,0.0003256711,0.00007611866],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008284325,0.0006914528,0.8417494,0.00025368016,0.00014826935,0.005171031,0.00074174145,0.000696229,0.07926571,0.00009716483,0.00028490936,0.06261602],"study_design_scores_gemma":[0.0001487854,0.008214842,0.97525907,0.000014236228,0.00008652551,0.0069550844,0.00026266428,0.00033251505,0.008010075,0.000040561972,0.0006675845,0.0000081557255],"about_ca_topic_score_codex":0.0011402952,"about_ca_topic_score_gemma":0.0017367069,"teacher_disagreement_score":0.0011402952,"about_ca_system_score_codex":0.00025493375,"about_ca_system_score_gemma":0.000188549,"threshold_uncertainty_score":0.002267301},"labels":[],"label_agreement":null},{"id":"W2080702078","doi":"10.1172/jci18237","title":"The fractalkine receptor CX3CR1 is a key mediator of atherogenesis","year":2003,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Toronto General Hospital","funders":"","keywords":"CX3CR1; Mediator; Key (lock); Receptor; Cell biology; Chemistry; Medicine; Computational biology; Biology; Chemokine receptor; Internal medicine; Chemokine; Ecology","score_opus":0.07141959655627994,"score_gpt":0.36201445029498897,"score_spread":0.290594853738709,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080702078","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.026541367,0.04138766,0.0012436134,0.85621333,0.04485156,0.00012034626,0.00019624461,0.00019363893,0.029252281],"genre_scores_gemma":[0.25113922,0.049176168,0.0016251086,0.35648844,0.30559886,0.00021024862,0.00023440596,0.000051480813,0.035476066],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996101,0.00011630143,0.000039869614,0.00005113324,0.00012242865,0.00006017365],"domain_scores_gemma":[0.99914134,0.00044380594,0.00010462425,0.00003374979,0.00017300133,0.00010360364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043662023,0.00040258252,0.0006937112,0.00027567858,0.0006905191,0.0009711037,0.0004610258,0.007016594,0.0033402517],"category_scores_gemma":[0.0038137638,0.00019348381,0.00024169139,0.00024608898,0.0009570769,0.00095920655,0.00028224415,0.00468856,0.0033950566],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077594066,0.0001409131,0.004865746,0.0005876141,0.00003526145,0.08170802,0.00023793797,0.00025896414,0.006913394,0.0073908144,0.7887657,0.10831964],"study_design_scores_gemma":[0.0005678954,0.0004054148,0.009400932,0.0005769447,0.000062457744,0.12875569,0.00028412338,0.0014331647,0.0036230497,0.013747409,0.84108883,0.000054112967],"about_ca_topic_score_codex":0.00050393323,"about_ca_topic_score_gemma":0.0005213863,"teacher_disagreement_score":0.007016594,"about_ca_system_score_codex":0.0012120636,"about_ca_system_score_gemma":0.0006350127,"threshold_uncertainty_score":0.011174202},"labels":[],"label_agreement":null},{"id":"W2081307885","doi":"10.1172/jci77193","title":"A brain network response to sham surgery","year":2014,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pain Management and Placebo Effect","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Parkinsonfonden; Canada Research Chairs; Canadian Institutes of Health Research; National Parkinson Foundation; Fondation pour la Recherche sur Alzheimer; Michael J. Fox Foundation for Parkinson's Research","keywords":"Medicine; Neuroscience; Bioinformatics; Psychology; Biology","score_opus":0.18335597957122807,"score_gpt":0.389292070360443,"score_spread":0.20593609078921493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081307885","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.41116995,0.0105565805,0.012934032,0.46752465,0.01507676,0.00023147921,0.00084942556,0.0006193086,0.08103778],"genre_scores_gemma":[0.90459776,0.0031376663,0.0019701715,0.06248148,0.01273099,0.00015308011,0.00018796844,0.00005146741,0.014689513],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9998343,0.00005775944,0.000008260297,0.000037727208,0.000040929965,0.000021097192],"domain_scores_gemma":[0.99916816,0.00049623207,0.00009063028,0.00006440331,0.00012241665,0.000058110345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003172988,0.00017953517,0.00019196045,0.0002408166,0.00045302894,0.0004784942,0.00024389492,0.0016336326,0.00376984],"category_scores_gemma":[0.002831396,0.00006153378,0.00017669004,0.00013927784,0.00060431816,0.0004691576,0.00021942907,0.0016895818,0.00062630995],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0068252105,0.0006082045,0.036685742,0.0007172643,0.00036292223,0.04387992,0.0011816209,0.0014767128,0.089140385,0.02287545,0.32344538,0.47280124],"study_design_scores_gemma":[0.0014921706,0.0051345737,0.33742708,0.00079540815,0.00045627813,0.11612836,0.0019966736,0.016088663,0.028359164,0.13055658,0.3613589,0.00020622335],"about_ca_topic_score_codex":0.0005205634,"about_ca_topic_score_gemma":0.0010436415,"teacher_disagreement_score":0.00376984,"about_ca_system_score_codex":0.0007267614,"about_ca_system_score_gemma":0.00020197012,"threshold_uncertainty_score":0.012611389},"labels":[],"label_agreement":null},{"id":"W2081736209","doi":"10.1172/jci30525","title":"A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health; Deutsche Forschungsgemeinschaft; Lymphoma Research Foundation","keywords":"Enhancer; Biology; Myeloid leukemia; Progenitor cell; Myeloid; Cancer research; Transcription factor; Molecular biology; Chromatin; Core binding factor; Leukemia; Single-nucleotide polymorphism; Cell biology; Gene; Genetics; Stem cell","score_opus":0.062083860409709604,"score_gpt":0.35878551316418006,"score_spread":0.29670165275447047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081736209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99750406,0.00031254554,0.0017254234,0.000041860545,0.000011740276,0.000009048446,0.000100163816,0.000043726457,0.00025154874],"genre_scores_gemma":[0.99832684,0.00011302925,0.0008378208,0.000036592937,0.000006458366,0.000008001604,0.00013537561,0.000014554387,0.00052137],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99988306,0.000031700583,0.000011977941,0.000036188016,0.000025288762,0.000011892085],"domain_scores_gemma":[0.9998834,0.00003183803,0.000045163568,0.0000090292415,0.0000055292962,0.000025095847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219217,0.00024314219,0.00020573653,0.00020482538,0.00008500286,0.00012753741,0.00011223924,0.0002385681,0.0014718131],"category_scores_gemma":[0.00018423407,0.00012695076,0.00013040073,0.000111218265,0.00018943471,0.000057964335,0.0001347452,0.0003951583,0.0003418905],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002917231,0.000049503495,0.002152986,0.000014516338,0.000014143763,0.00017458515,0.000012561393,0.00008268814,0.99472886,0.00009329108,0.000029019207,0.0023561702],"study_design_scores_gemma":[0.0002270321,0.0021483123,0.20821626,0.000030585066,0.00020203863,0.0094309235,0.00004956234,0.0058691497,0.7689541,0.0005029041,0.0043387725,0.00003030815],"about_ca_topic_score_codex":0.00014474709,"about_ca_topic_score_gemma":0.00032432607,"teacher_disagreement_score":0.0014718131,"about_ca_system_score_codex":0.00008381314,"about_ca_system_score_gemma":0.000057967536,"threshold_uncertainty_score":0.0049237013},"labels":[],"label_agreement":null},{"id":"W2081840097","doi":"10.1172/jci69411","title":"Metabolic network as a progression biomarker of premanifest Huntington’s disease","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; University of California, San Diego; University of Toronto; CHDI Foundation; National Institutes of Health; Pfizer","keywords":"Medicine; Huntington's disease; Putamen; Biomarker; Metabolic network; Cohort; Disease; Internal medicine; Neuroimaging; Imaging biomarker; Oncology; Pathology; Bioinformatics; Magnetic resonance imaging; Biology; Radiology; Psychiatry","score_opus":0.09943676473839468,"score_gpt":0.3908154313540809,"score_spread":0.29137866661568623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081840097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99772125,0.00014207684,0.0015289609,0.00003523759,0.000001909897,0.000014142396,0.00023267344,0.000014635823,0.00030911036],"genre_scores_gemma":[0.99833435,0.00007496992,0.0011822662,0.0000059074277,0.00000294435,0.000009888316,0.0003137172,0.0000019100214,0.00007402706],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9999068,0.000029950745,0.0000070417286,0.000028787066,0.00001742695,0.000010030406],"domain_scores_gemma":[0.99927074,0.00024348653,0.0003052209,0.00004632049,0.00006958982,0.000064752974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058769307,0.0003069209,0.00022013171,0.000858676,0.00015077357,0.00040509927,0.00016587501,0.0003003966,0.00068882894],"category_scores_gemma":[0.0017743246,0.00010537609,0.00018262501,0.0003377528,0.0001729168,0.00030041838,0.00027896586,0.00029696472,0.00007988938],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079001265,0.000107949796,0.9639349,0.000037501573,0.00016146686,0.00014661415,0.00011980903,0.005814992,0.010874553,0.00026334432,0.00016937841,0.0175794],"study_design_scores_gemma":[0.000013570562,0.0002912212,0.9719747,0.00000833994,0.000062378465,0.00033057894,0.00005695902,0.024491772,0.0019392486,0.00057405396,0.00024822107,0.000009027193],"about_ca_topic_score_codex":0.0023078793,"about_ca_topic_score_gemma":0.0037081405,"teacher_disagreement_score":0.0023078793,"about_ca_system_score_codex":0.00033949627,"about_ca_system_score_gemma":0.00020574947,"threshold_uncertainty_score":0.004588902},"labels":[],"label_agreement":null},{"id":"W2082720266","doi":"10.1172/jci36625","title":"Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Health and Medical Research Council; Australian Research Council; Medical Research Council; University of Sydney; Université de Sherbrooke","keywords":"Genetics; Gene; Phenotype; Biology; Allele; Transporter; Amino acid; Amino acid transporter; Mendelian inheritance; Glycine; Mutation; Proline; Mutagenesis","score_opus":0.07802675084849116,"score_gpt":0.3483201242333176,"score_spread":0.27029337338482645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082720266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958246,0.00077263464,0.0016786758,0.0000688817,0.000009335702,0.000018833043,0.00020237817,0.00007174987,0.0013528282],"genre_scores_gemma":[0.99733716,0.0006188172,0.0011919265,0.000047825968,0.00001653242,0.0000073350425,0.00023660687,0.000020207093,0.00052359304],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99988675,0.000016507893,0.000011711231,0.000035073754,0.000028317692,0.000021603555],"domain_scores_gemma":[0.99985695,0.000022103757,0.00006455431,0.000006817751,0.000008876451,0.000040698054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000097510434,0.00072160194,0.00025238155,0.00053965166,0.00016615298,0.0002198257,0.00014081957,0.00026201515,0.0016862729],"category_scores_gemma":[0.00029171415,0.00014512202,0.00015153992,0.00042626698,0.00033434937,0.00016622889,0.00034505283,0.00024308842,0.00016708509],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00165454,0.00018751505,0.26367107,0.00041392402,0.0003082515,0.09285072,0.000802929,0.0010957822,0.5971058,0.0016292903,0.0010478048,0.03923236],"study_design_scores_gemma":[0.00009707619,0.00049248163,0.7291643,0.00005623673,0.00026513112,0.1949479,0.00041852673,0.0016935919,0.06669112,0.0012863819,0.0048425216,0.000044806802],"about_ca_topic_score_codex":0.0006002314,"about_ca_topic_score_gemma":0.00058039784,"teacher_disagreement_score":0.0016862729,"about_ca_system_score_codex":0.00012962168,"about_ca_system_score_gemma":0.00015508836,"threshold_uncertainty_score":0.0056411624},"labels":[],"label_agreement":null},{"id":"W2083332835","doi":"10.1172/jci20726","title":"Complement-independent Ab-induced peroxide lysis of platelets requires 12-lipoxygenase and a platelet NADPH oxidase pathway","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; National Institutes of Health; School of Medicine, New York University; York University; American Society of Hematology","keywords":"Platelet; NADPH oxidase; Chemistry; Reactive oxygen species; Platelet activation; Lipoxygenase; Complement system; Alternative complement pathway; Biochemistry; Enzyme; Cell biology; Biology; Immunology; Antibody","score_opus":0.09294358506154475,"score_gpt":0.364539668792146,"score_spread":0.27159608373060123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083332835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863071,0.0038621498,0.0071452507,0.0003409948,0.000059067985,0.00006298011,0.00010759054,0.00006522821,0.0020497732],"genre_scores_gemma":[0.99622416,0.0007984851,0.0017072697,0.000043017422,0.000020925607,0.000022931492,0.00019042494,0.000004045711,0.0009887641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998109,0.000052405994,0.00001645785,0.000019342513,0.000056308956,0.00004470138],"domain_scores_gemma":[0.9998733,0.000026536582,0.000031806387,0.00002144048,0.000026611622,0.00002026814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025576857,0.00027131988,0.00013099407,0.0001694904,0.00015421376,0.00027071987,0.00015563337,0.0003224654,0.0013667777],"category_scores_gemma":[0.00029169774,0.000118418495,0.0002256544,0.00007408175,0.00018136794,0.00025291077,0.0002497442,0.0005601462,0.00024850477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043384702,0.00007137752,0.0008996963,0.000056664885,0.00001989933,0.00059986365,0.000031569092,0.00003653229,0.9924648,0.00053071504,0.000108250795,0.00474684],"study_design_scores_gemma":[0.00016888598,0.0019552498,0.0247479,0.000018463614,0.00005988061,0.004623929,0.00006746113,0.0014394885,0.96248996,0.0005753368,0.003842654,0.000010736647],"about_ca_topic_score_codex":0.0003143103,"about_ca_topic_score_gemma":0.0003720045,"teacher_disagreement_score":0.0013667777,"about_ca_system_score_codex":0.00015147692,"about_ca_system_score_gemma":0.00019210675,"threshold_uncertainty_score":0.0045722723},"labels":[],"label_agreement":null},{"id":"W2083578935","doi":"10.1172/jci15990","title":"Thyroid functions of mouse cathepsins B, K, and L","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":223,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Shriners Hospitals for Children; McGill University","keywords":"Thyroglobulin; Cathepsin; Cathepsin B; Chemistry; Proteolytic enzymes; Thyroid; Cathepsin D; Cathepsin H; Biochemistry; Proteolysis; Molecular biology; Endocrinology; Internal medicine; Biology; Enzyme; Medicine","score_opus":0.0756598671017931,"score_gpt":0.3674383006342089,"score_spread":0.29177843353241584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083578935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907822,0.004433273,0.002186243,0.00017291645,0.000019160003,0.000020120051,0.00055282516,0.00011049231,0.001722746],"genre_scores_gemma":[0.99176085,0.0015090425,0.0015724088,0.000048802645,0.0000082997685,0.00003629317,0.0008662992,0.000033060944,0.004165005],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976736,0.000030358806,0.00003736598,0.000052984684,0.000044333352,0.000067495544],"domain_scores_gemma":[0.9996716,0.000031454136,0.0001167118,0.000041092877,0.000038934275,0.00010023558],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023240436,0.00036159714,0.00018444395,0.0005999114,0.00024000951,0.00054831355,0.00020547441,0.00035624497,0.0014583541],"category_scores_gemma":[0.00021177932,0.0002502068,0.00040637044,0.00018343722,0.00030502304,0.00028727885,0.00021859712,0.00046126847,0.00042951276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052899844,0.00002638203,0.000890498,0.000037690923,0.00001152862,0.000075789445,0.0000312797,0.000040264484,0.99628395,0.00017229744,0.000052823292,0.0018485707],"study_design_scores_gemma":[0.00010265579,0.00048168597,0.012477414,0.000019807612,0.000089537105,0.0013565454,0.000094832045,0.0006148182,0.98015594,0.00017519601,0.0044198954,0.00001163658],"about_ca_topic_score_codex":0.0015364739,"about_ca_topic_score_gemma":0.0013550726,"teacher_disagreement_score":0.0015364739,"about_ca_system_score_codex":0.0007350445,"about_ca_system_score_gemma":0.00038019774,"threshold_uncertainty_score":0.0053331256},"labels":[],"label_agreement":null},{"id":"W2085710584","doi":"10.1172/jci34470","title":"A skewed view of X chromosome inactivation","year":2007,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"University of California, San Francisco; National Institutes of Health","keywords":"X-inactivation; X chromosome; Skewed X-inactivation; Genetics; Biology; Somatic cell; XIST; Chromosome; Locus (genetics); Dosage compensation; Gene","score_opus":0.05276258147147096,"score_gpt":0.3493210499933569,"score_spread":0.29655846852188594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085710584","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0140636,0.014622471,0.0036610956,0.9085957,0.029571898,0.000036421072,0.00011962573,0.00028662093,0.029042661],"genre_scores_gemma":[0.16344498,0.01998075,0.00265185,0.6334652,0.14802545,0.000072839175,0.00010583654,0.00007824383,0.03217488],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991074,0.00031271554,0.00007109706,0.00019133973,0.00022658471,0.00009082888],"domain_scores_gemma":[0.9982405,0.0009804325,0.00014502842,0.00017424353,0.00029304228,0.0001667426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007770487,0.0006448181,0.0006383008,0.00044860225,0.00071802945,0.0012892516,0.0009891306,0.009293394,0.005138875],"category_scores_gemma":[0.004829937,0.00023746089,0.00041706025,0.0002722854,0.002420862,0.001892651,0.0006092823,0.0099537475,0.0038904832],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004895565,0.000120196026,0.0074820262,0.0003562683,0.00008612514,0.07182945,0.0005581293,0.0004907799,0.0060877944,0.04882368,0.7753427,0.08833318],"study_design_scores_gemma":[0.00031528244,0.00034548857,0.004319664,0.00035257585,0.00006358263,0.24366458,0.0006033772,0.002096155,0.0028830953,0.060373265,0.6848891,0.00009378086],"about_ca_topic_score_codex":0.0003822141,"about_ca_topic_score_gemma":0.00041171128,"teacher_disagreement_score":0.009293394,"about_ca_system_score_codex":0.000869374,"about_ca_system_score_gemma":0.00033370292,"threshold_uncertainty_score":0.017191231},"labels":[],"label_agreement":null},{"id":"W2085832579","doi":"10.1172/jci65952","title":"Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":280,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institutes of Health; Canadian Diabetes Association; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Sanofi","keywords":"Osteocalcin; Endocrinology; Internal medicine; Biology; Leydig cell; Luteinizing hormone; Testosterone (patch); Osteoblast; Hormone; Medicine; Alkaline phosphatase","score_opus":0.09989158293980625,"score_gpt":0.3939814925432493,"score_spread":0.29408990960344306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085832579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99047065,0.003930235,0.0012619066,0.00023637248,0.000024413905,0.000031310665,0.00045501758,0.00008143853,0.003508684],"genre_scores_gemma":[0.99747485,0.00081448513,0.00046894237,0.00006221806,0.000006362901,0.000011561029,0.0002436477,0.000010570389,0.0009073103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986744,0.000023211265,0.000005156104,0.000026369447,0.000049931536,0.000027856337],"domain_scores_gemma":[0.99994123,0.000008757241,0.000016825252,0.0000067729475,0.0000068361655,0.000019606285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013967643,0.0001287774,0.00015504076,0.00039699182,0.0001347808,0.00034134157,0.000107582906,0.00015193767,0.0014478907],"category_scores_gemma":[0.00015019918,0.00007345147,0.00013516769,0.00018311289,0.00032849502,0.000076558135,0.0001481218,0.00029018574,0.00017506086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006013462,0.00006667624,0.0062832255,0.0000306889,0.00001544498,0.0004083262,0.00005312234,0.0001304432,0.982474,0.00046319354,0.00028849702,0.009184953],"study_design_scores_gemma":[0.0002589848,0.0012366667,0.20505676,0.000027281976,0.000104202605,0.00560145,0.00018534502,0.0016385054,0.7609912,0.000724003,0.02415705,0.000018475108],"about_ca_topic_score_codex":0.0011596296,"about_ca_topic_score_gemma":0.0017484947,"teacher_disagreement_score":0.0014478907,"about_ca_system_score_codex":0.0003171101,"about_ca_system_score_gemma":0.00034112102,"threshold_uncertainty_score":0.0048436522},"labels":[],"label_agreement":null},{"id":"W2086051048","doi":"10.1172/jci40987","title":"Right to reform","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Healthcare Policy and Management","field":"Economics, Econometrics and Finance","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"University of Pennsylvania","keywords":"Medicine","score_opus":0.1970992928036306,"score_gpt":0.4012697615168239,"score_spread":0.20417046871319333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086051048","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006780546,0.003202245,0.002673872,0.8461208,0.009601203,0.000043042284,0.00017635239,0.00015545095,0.13734908],"genre_scores_gemma":[0.055062227,0.0034003274,0.004463229,0.69553125,0.0085732695,0.00016203153,0.00031342378,0.00021777935,0.23227634],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9936824,0.0017903653,0.00023190335,0.001063288,0.0018090344,0.0014229924],"domain_scores_gemma":[0.9912744,0.0017860378,0.0006276067,0.0016243088,0.0026273394,0.0020603135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0072775865,0.0005499623,0.0007267856,0.0005834325,0.0034023554,0.009073124,0.0012169959,0.010808876,0.081174],"category_scores_gemma":[0.0436256,0.00025743758,0.00078043813,0.0004201843,0.0063693197,0.012498978,0.0046257316,0.015465332,0.026748506],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002353951,0.00006161376,0.00025680772,0.000053792523,0.000009968701,0.00006034562,0.00021971189,0.00009425335,0.000088968765,0.50456935,0.47292528,0.021636402],"study_design_scores_gemma":[0.00003102311,0.000018233008,0.00023013464,0.0001801173,0.00000532198,0.000050569735,0.00027427782,0.000105278734,0.000085509666,0.12284902,0.87615913,0.000011382971],"about_ca_topic_score_codex":0.0070721116,"about_ca_topic_score_gemma":0.005912882,"teacher_disagreement_score":0.081174,"about_ca_system_score_codex":0.0033385567,"about_ca_system_score_gemma":0.009008361,"threshold_uncertainty_score":0.2715541},"labels":[],"label_agreement":null},{"id":"W2086714780","doi":"10.1172/jci59755","title":"The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":763,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Acetaminophen; DNA fragmentation; Fragmentation (computing); Mitochondrial DNA; Nuclear DNA; Toxicity; Apoptosis; DNA damage; Programmed cell death; Glutamate dehydrogenase; Mitochondrial toxicity; Mitochondrion; Liver injury; Biology; Pharmacology; Internal medicine; Medicine; Glutamate receptor; DNA; Biochemistry","score_opus":0.32416315730584017,"score_gpt":0.48222312165208997,"score_spread":0.1580599643462498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086714780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96485484,0.013021403,0.016105942,0.0006418402,0.00009118678,0.00033374885,0.00069243024,0.0001645059,0.004094112],"genre_scores_gemma":[0.9886691,0.005157498,0.0035337773,0.00024264133,0.000021479196,0.00015790177,0.00038301016,0.0000066319485,0.001828015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998103,0.00005566214,0.000014684354,0.000040314386,0.000054770964,0.000024232144],"domain_scores_gemma":[0.99989605,0.000008880134,0.00005557663,0.00001216728,0.0000126233335,0.000014741967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022699576,0.0006508019,0.00018244992,0.00049991923,0.00021658059,0.00023425037,0.00017855233,0.00037116246,0.0018476221],"category_scores_gemma":[0.00015439841,0.0001597149,0.00028308472,0.000241036,0.00040628752,0.00031217505,0.00028067647,0.00051381,0.00024966302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016860884,0.00033565192,0.008543983,0.00035066175,0.000117035495,0.00071309094,0.00010157733,0.00019153453,0.9643702,0.00068510254,0.0003807621,0.022524357],"study_design_scores_gemma":[0.00022157462,0.008078218,0.1540072,0.00015236098,0.00019913356,0.007350014,0.0002882793,0.0018797041,0.8120699,0.0010115431,0.01469728,0.000044816992],"about_ca_topic_score_codex":0.00049090345,"about_ca_topic_score_gemma":0.0006678798,"teacher_disagreement_score":0.0018476221,"about_ca_system_score_codex":0.00025622448,"about_ca_system_score_gemma":0.0002248027,"threshold_uncertainty_score":0.006180942},"labels":[],"label_agreement":null},{"id":"W2087185853","doi":"10.1172/jci34316","title":"Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":284,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; James N. Kirby Foundation; National Eye Institute; National Institutes of Health; Research to Prevent Blindness; F. M. Kirby Foundation","keywords":"ABCA4; Biology; Genetic enhancement; Transduction (biophysics); Gene delivery; Retinal degeneration; Gene; Capsid; Adeno-associated virus; Retinitis pigmentosa; Vector (molecular biology); Viral vector; Virology; Genetics; Recombinant DNA","score_opus":0.04523876992661468,"score_gpt":0.365887957769594,"score_spread":0.3206491878429793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087185853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85034865,0.005452095,0.12222841,0.0007231975,0.00050898996,0.0011071165,0.004102811,0.003273128,0.0122556845],"genre_scores_gemma":[0.89347005,0.0049508526,0.07417542,0.0002896433,0.00010807182,0.00081753725,0.0058136894,0.00078484544,0.019589946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992742,0.00014418295,0.00011542955,0.00018016889,0.00019360092,0.00009240055],"domain_scores_gemma":[0.999474,0.00010545599,0.00018302772,0.0001099462,0.000033426142,0.00009413251],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008274525,0.0009064634,0.0004235485,0.00089016097,0.00023818172,0.00068698573,0.000531181,0.000862512,0.0026980487],"category_scores_gemma":[0.00036440347,0.0007751114,0.0005445191,0.00035340086,0.0006127943,0.00061572355,0.0004412958,0.0012924365,0.0018586958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005914383,0.000052146483,0.00007302481,0.0000399686,0.000007706467,0.000033884633,0.000023345137,0.000048896352,0.9975048,0.00042636975,0.00009176289,0.0016389985],"study_design_scores_gemma":[0.00005204857,0.00055750844,0.000985058,0.000021732194,0.000035750974,0.00037997946,0.00001620251,0.000793459,0.9894678,0.00019320934,0.0074859513,0.000011281193],"about_ca_topic_score_codex":0.0002958657,"about_ca_topic_score_gemma":0.0004268515,"teacher_disagreement_score":0.0026980487,"about_ca_system_score_codex":0.00037164928,"about_ca_system_score_gemma":0.0003178586,"threshold_uncertainty_score":0.009025812},"labels":[],"label_agreement":null},{"id":"W2087351164","doi":"10.1172/jci43008","title":"MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":335,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; University of California, San Diego; National Cancer Institute; National Institutes of Health; Fondazione Cariplo; National Heart, Lung, and Blood Institute; Foundation for Cardiovascular Research; Howard Hughes Medical Institute","keywords":"mTORC1; PI3K/AKT/mTOR pathway; Autophagy; Mechanistic target of rapamycin; Myocyte; Pressure overload; mTORC2; Heart failure; Biology; Eukaryotic initiation factor; Cell biology; Internal medicine; Muscle hypertrophy; Apoptosis; Endocrinology; Translation (biology); Signal transduction; Medicine; Cardiac hypertrophy; Gene; Messenger RNA; Biochemistry","score_opus":0.040299407747075265,"score_gpt":0.338118091993733,"score_spread":0.29781868424665775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087351164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95557255,0.009873785,0.017574241,0.0020528603,0.0004030106,0.00044564268,0.004250396,0.0015184302,0.008309155],"genre_scores_gemma":[0.9648671,0.005937557,0.010573994,0.00055216457,0.000100333345,0.0007820567,0.0024549263,0.0002256493,0.014506279],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995523,0.00006868242,0.000046754336,0.00010744225,0.0001176136,0.00010720285],"domain_scores_gemma":[0.9998056,0.000014308711,0.000076688084,0.000017199445,0.00001806684,0.00006816885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052724895,0.000978275,0.0005685136,0.0014808282,0.000616675,0.0006189358,0.00068091543,0.00090746925,0.002326713],"category_scores_gemma":[0.00017380712,0.00060055725,0.00057749974,0.00046060412,0.0009006831,0.0005095682,0.00036707302,0.0017955798,0.0008199821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001497264,0.00038812487,0.00044132132,0.00013646552,0.00003483714,0.000115594536,0.00003985388,0.00028959897,0.989326,0.0008843147,0.0007681418,0.0060785944],"study_design_scores_gemma":[0.00089502387,0.0026109389,0.011237491,0.00006991207,0.00017674275,0.00081663625,0.000087765686,0.0054669753,0.9580688,0.00068295916,0.019851921,0.00003483382],"about_ca_topic_score_codex":0.0011850066,"about_ca_topic_score_gemma":0.0023960574,"teacher_disagreement_score":0.002326713,"about_ca_system_score_codex":0.0009230918,"about_ca_system_score_gemma":0.0008360641,"threshold_uncertainty_score":0.0077836514},"labels":[],"label_agreement":null},{"id":"W2087962053","doi":"10.1172/jci29528","title":"Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":332,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Insulin resistance; Endocrinology; Internal medicine; Adipose tissue; PI3K/AKT/mTOR pathway; P70-S6 Kinase 1; Ribosomal protein s6; Lipolysis; Biology; Protein kinase B; Adipogenesis; Insulin; Signal transduction; Medicine; Cell biology","score_opus":0.05349405494463537,"score_gpt":0.3604036181771676,"score_spread":0.3069095632325322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087962053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99137443,0.0015544157,0.0033799168,0.0002920251,0.00006811984,0.000043928907,0.0014648307,0.00035887925,0.0014635047],"genre_scores_gemma":[0.98112315,0.0020866953,0.0061945547,0.00023938995,0.00004592107,0.0002045616,0.0022723388,0.0002353677,0.007598034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996265,0.00005067952,0.000040929193,0.000115432376,0.0000926005,0.00007389222],"domain_scores_gemma":[0.9996542,0.000025819281,0.00012034462,0.000032897533,0.000023426386,0.0001433195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022416851,0.0012022789,0.0006327755,0.0015505302,0.00028928192,0.0005863791,0.00033087019,0.00064476405,0.002556317],"category_scores_gemma":[0.00017971106,0.00062620995,0.00045910766,0.00062105234,0.00063559634,0.00042963665,0.00035261357,0.0016472137,0.0006883952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008090658,0.00009390399,0.0004183417,0.000031230615,0.000019173363,0.000091107184,0.000019279878,0.000058623787,0.99708563,0.00010844585,0.00006633253,0.0011988766],"study_design_scores_gemma":[0.0004052979,0.0024096665,0.047464292,0.000046510035,0.00019476509,0.0024718686,0.000120153665,0.0025716338,0.938379,0.0004595698,0.0054180617,0.000059280304],"about_ca_topic_score_codex":0.00066521467,"about_ca_topic_score_gemma":0.00094149937,"teacher_disagreement_score":0.002556317,"about_ca_system_score_codex":0.00047349444,"about_ca_system_score_gemma":0.00027268758,"threshold_uncertainty_score":0.008551776},"labels":[],"label_agreement":null},{"id":"W2090490099","doi":"10.1172/jci72829","title":"Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":317,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Center for Research Resources; School of Medicine, Indiana University; Yale University; National Institutes of Health; Kyowa Hakko Kirin; National Institute of Diabetes and Digestive and Kidney Diseases; McGill University; Johns Hopkins University","keywords":"Hypophosphatemia; Internal medicine; Endocrinology; Medicine; Tolerability; Placebo; PHEX; Reabsorption; Kidney; Rickets; Vitamin D and neurology; Adverse effect; Pathology","score_opus":0.06984510509781217,"score_gpt":0.4148532662454616,"score_spread":0.34500816114764943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090490099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894796,0.0029133954,0.0005768941,0.0005518649,0.0007512857,0.0035460382,0.00061319437,0.00010744898,0.001460431],"genre_scores_gemma":[0.9887439,0.0013508494,0.0010657851,0.0008193453,0.00050957967,0.0039533894,0.00053831557,0.000016382224,0.003002602],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99918586,0.00046059996,0.000046921552,0.00012635515,0.000054524506,0.00012565195],"domain_scores_gemma":[0.9986594,0.00038349166,0.00028694412,0.00011331626,0.00009177672,0.00046505674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014964865,0.0012539488,0.002916292,0.00030893803,0.00037204847,0.0008492481,0.0008462641,0.0016409,0.00673817],"category_scores_gemma":[0.0017222983,0.0005660008,0.0011096848,0.0002933015,0.0011291051,0.00062884274,0.00040907876,0.0025512923,0.0009334072],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.99118996,0.0023219702,0.0002227091,0.00011576021,0.0002308439,0.000017336837,0.000012135135,0.000114200186,0.0008617702,0.000042251737,0.00021298384,0.0046581454],"study_design_scores_gemma":[0.8909457,0.10669305,0.0010741614,0.000013433548,0.00016775154,0.000027521197,0.000011274852,0.00029060149,0.00028977127,0.00007903583,0.0003992935,0.000008548473],"about_ca_topic_score_codex":0.00097547594,"about_ca_topic_score_gemma":0.0014615072,"teacher_disagreement_score":0.00673817,"about_ca_system_score_codex":0.0006191089,"about_ca_system_score_gemma":0.0013627887,"threshold_uncertainty_score":0.022541404},"labels":[],"label_agreement":null},{"id":"W2090952129","doi":"10.1172/jci21128","title":"Assessing risk is the business of prion disease research","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Disease; Medicine; Virology; Business; Computational biology; Biology; Pathology","score_opus":0.16137614360186936,"score_gpt":0.47228510823407344,"score_spread":0.3109089646322041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090952129","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001992315,0.053668708,0.008438519,0.90755135,0.005543235,0.00004506032,0.00016568523,0.00020386667,0.02239125],"genre_scores_gemma":[0.23784718,0.21669462,0.032884654,0.44885692,0.045963764,0.00036884757,0.00061849505,0.00051310414,0.016252423],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9146824,0.05196428,0.0039070123,0.004860364,0.022469873,0.0021161018],"domain_scores_gemma":[0.6918784,0.23440927,0.012421018,0.017627843,0.030443022,0.013220523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.095852695,0.001585602,0.0029332151,0.006216292,0.0047221123,0.024231646,0.0034337135,0.016627816,0.009431094],"category_scores_gemma":[0.2128893,0.0010621364,0.0014117258,0.0045551923,0.026625566,0.040607303,0.006602592,0.020981982,0.005120621],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042638843,0.0002517883,0.008215453,0.0010784484,0.0004711837,0.00045644114,0.0033602668,0.0014333144,0.0006035973,0.35065064,0.29663163,0.33642095],"study_design_scores_gemma":[0.00007179452,0.000115413175,0.0010849326,0.0019409966,0.000087791,0.0003008946,0.0019704653,0.0006842783,0.00028277488,0.7215228,0.27182865,0.00010922173],"about_ca_topic_score_codex":0.0044749817,"about_ca_topic_score_gemma":0.003013952,"teacher_disagreement_score":0.095852695,"about_ca_system_score_codex":0.0063867467,"about_ca_system_score_gemma":0.013542561,"threshold_uncertainty_score":0.50692356},"labels":[],"label_agreement":null},{"id":"W2091242368","doi":"10.1172/jci57100","title":"Breast cancer — one term, many entities?","year":2011,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":230,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"McGill University Health Centre; McGill University","keywords":"Breast cancer; Cancer; Breast tumor; Disease; Computational biology; Bioinformatics; Medicine; Tumor heterogeneity; Biology; Cancer research; Pathology; Internal medicine","score_opus":0.4923396356444193,"score_gpt":0.5576649504711761,"score_spread":0.06532531482675685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091242368","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007903194,0.99377316,0.00013288936,0.0033401863,0.0012202115,0.00000232542,0.00001030551,0.000008753808,0.0014330925],"genre_scores_gemma":[0.0012983074,0.99243647,0.00034639693,0.0024058062,0.0018882939,0.0000055496307,0.000028428947,0.000003738182,0.0015869896],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996124,0.00011746632,0.000049049082,0.000053957236,0.00013204875,0.00003506373],"domain_scores_gemma":[0.99942964,0.00024589067,0.00006079005,0.000031553856,0.00015637619,0.00007571506],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077117124,0.00086083706,0.0017913781,0.0021030917,0.00044372937,0.0017246085,0.00097386335,0.0013278307,0.0025379707],"category_scores_gemma":[0.0014156508,0.00024659277,0.00033171757,0.0028787847,0.0014908051,0.0040028915,0.0010825435,0.0028015797,0.0025189754],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060486353,0.000039153536,0.0004154319,0.004423095,0.00006138792,0.00037363186,0.00015889957,0.00014375107,0.0007731897,0.01081153,0.17679776,0.80594164],"study_design_scores_gemma":[0.000006586939,0.000021539941,0.00040961106,0.0019239149,0.000028663897,0.0025799882,0.00021484826,0.000030823485,0.00007646936,0.0050315033,0.9896646,0.000011458765],"about_ca_topic_score_codex":0.0013639267,"about_ca_topic_score_gemma":0.002458247,"teacher_disagreement_score":0.0025379707,"about_ca_system_score_codex":0.0010667853,"about_ca_system_score_gemma":0.0015751348,"threshold_uncertainty_score":0.008490324},"labels":[],"label_agreement":null},{"id":"W2091379168","doi":"10.1172/jci46043","title":"Circadian rhythms, sleep, and metabolism","year":2011,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":719,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Sleep & Circadian Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health","keywords":"Circadian rhythm; Biology; Bacterial circadian rhythms; Neuroscience; Circadian clock; Sleep (system call); CLOCK; Energy homeostasis; Light effects on circadian rhythm; Chronobiology; Obesity; Endocrinology; Computer science","score_opus":0.222852640695602,"score_gpt":0.40343155026654975,"score_spread":0.18057890957094774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091379168","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009940133,0.9983095,0.000094006966,0.00025583076,0.00026216774,0.0000025347772,0.000006618459,0.0000063032176,0.00096358376],"genre_scores_gemma":[0.0008977938,0.99777955,0.000105211766,0.00011776161,0.00032230897,0.000004433507,0.000011574723,8.704993e-7,0.0007605828],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99988115,0.000023474715,0.000016601613,0.000020332342,0.000045233166,0.000013265568],"domain_scores_gemma":[0.9998795,0.00003658392,0.000019936499,0.000005306549,0.000037335725,0.000021382642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033164772,0.00068689545,0.00091914024,0.0012578215,0.00032286716,0.00080985663,0.00057725894,0.00086738734,0.0022340277],"category_scores_gemma":[0.0003789163,0.00017512096,0.00023169082,0.0013018989,0.00057691627,0.0008238299,0.00058981,0.0012602822,0.0017057696],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085171654,0.00006636757,0.0003174604,0.0069390964,0.00005814443,0.00034371822,0.00010655559,0.00029695695,0.003562911,0.007295805,0.04267303,0.9382547],"study_design_scores_gemma":[0.000012638769,0.0000693235,0.0020392474,0.0019326163,0.000030830164,0.0016675827,0.00008560415,0.00006509191,0.00042912125,0.004565128,0.98908734,0.000015476868],"about_ca_topic_score_codex":0.0015967854,"about_ca_topic_score_gemma":0.0027808521,"teacher_disagreement_score":0.0022340277,"about_ca_system_score_codex":0.00071538176,"about_ca_system_score_gemma":0.00096289255,"threshold_uncertainty_score":0.007473588},"labels":[],"label_agreement":null},{"id":"W2091530696","doi":"10.1172/jci21003","title":"Nitrate tolerance, oxidative stress, and mitochondrial function: another worrisome chapter on the effects of organic nitrates","year":2004,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Oxidative stress; Nitrate; In vivo; Aldehyde dehydrogenase; Mitochondrion; Chemistry; Denitrification; Oxidative phosphorylation; Function (biology); Biochemistry; Enzyme; Biology; Cell biology; Organic chemistry; Biotechnology; Nitrogen","score_opus":0.035290181659899916,"score_gpt":0.2968640424508075,"score_spread":0.2615738607909076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091530696","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001791152,0.06317472,0.0004910875,0.8273962,0.101758964,0.000029983621,0.00004416753,0.00004638134,0.0052672755],"genre_scores_gemma":[0.0069783283,0.04525062,0.00058883266,0.46109468,0.46883228,0.000042889034,0.000034631717,0.000032221873,0.017145488],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99914277,0.00019456192,0.00012804016,0.00009267864,0.00034163016,0.00010028015],"domain_scores_gemma":[0.997881,0.0014703366,0.000107075466,0.00006516044,0.0002760787,0.0002002951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00095530896,0.0008309056,0.001413744,0.00066148594,0.001372246,0.0018040953,0.0009741556,0.014955175,0.003787483],"category_scores_gemma":[0.00349325,0.0003638725,0.0007938282,0.0003583384,0.0016892449,0.0026571038,0.0005750352,0.01521807,0.0019201904],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016723672,0.00013825698,0.0005862219,0.00043480616,0.000035889167,0.009309986,0.0001804909,0.00010357428,0.0015635187,0.0034749033,0.9328691,0.05113613],"study_design_scores_gemma":[0.00016057285,0.00024335635,0.001648638,0.0005780898,0.000045206252,0.019182706,0.0002953818,0.00029882946,0.00080401247,0.010021453,0.96668106,0.000040672454],"about_ca_topic_score_codex":0.00060498755,"about_ca_topic_score_gemma":0.0015190294,"teacher_disagreement_score":0.014955175,"about_ca_system_score_codex":0.0015461242,"about_ca_system_score_gemma":0.0007257108,"threshold_uncertainty_score":0.012670398},"labels":[],"label_agreement":null},{"id":"W2091899323","doi":"10.1172/jci22486","title":"Ikaros integrates endocrine and immune system development","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Ontario Institute for Cancer Research; Sunnybrook Health Science Centre; Health Sciences Centre; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Hormone; Biology; Glucocorticoid; Lymphopoiesis; Endocrine system; Population; Haematopoiesis; Endocrinology; Transcription factor; Immunology; Proopiomelanocortin; Internal medicine; Medicine; Stem cell; Gene; Cell biology; Genetics","score_opus":0.0809858429001423,"score_gpt":0.4030542107000146,"score_spread":0.32206836779987236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091899323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96502054,0.0073923357,0.0100006275,0.00051082205,0.00024286257,0.000030003182,0.001035847,0.0010083361,0.0147586465],"genre_scores_gemma":[0.9885151,0.0012759248,0.0021637012,0.00006456001,0.000051606497,0.000015879683,0.00073021854,0.000052188134,0.0071308683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980026,0.000021058322,0.000015095241,0.000050436374,0.00004277909,0.00007030314],"domain_scores_gemma":[0.9998373,0.000008934502,0.000038074748,0.000019557414,0.00002877746,0.000067461595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017283422,0.0003586412,0.00021617417,0.00038150424,0.00025001483,0.0004861729,0.00025778855,0.00018705043,0.0026719016],"category_scores_gemma":[0.00018303678,0.000115473194,0.00022142757,0.00015930196,0.00037083015,0.0004576358,0.00042216707,0.0005261312,0.0010466564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003151681,0.000018979987,0.0014563283,0.00004417535,0.0000059822364,0.0002060375,0.000046963734,0.000069016096,0.9883329,0.0006340016,0.00022771522,0.008642737],"study_design_scores_gemma":[0.00010041176,0.00046173725,0.050785076,0.00003650492,0.0000887301,0.0024229207,0.00037730995,0.0014507754,0.9041771,0.0019279809,0.038141258,0.000030206347],"about_ca_topic_score_codex":0.0003640535,"about_ca_topic_score_gemma":0.0006098979,"teacher_disagreement_score":0.0026719016,"about_ca_system_score_codex":0.00041973815,"about_ca_system_score_gemma":0.00029808434,"threshold_uncertainty_score":0.008938372},"labels":[],"label_agreement":null},{"id":"W2092503047","doi":"10.1172/jci63186","title":"Pathogenesis of follicular lymphoma","year":2012,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":309,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; BC Cancer Agency; Canadian Institutes of Health Research; Ligue Genevoise Contre le Cancer; Terry Fox Foundation","keywords":"Follicular lymphoma; Biology; Germinal center; Cancer research; Neoplastic transformation; Immune system; Lymphoma; Stromal cell; Immunology; Tumor microenvironment; Crosstalk; Malignant transformation; B cell; Gene; Genetics; Antibody; Carcinogenesis","score_opus":0.22437060783493384,"score_gpt":0.4434498753022194,"score_spread":0.21907926746728557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092503047","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004237007,0.99799985,0.0001580548,0.0003088984,0.00008928964,0.0000041736034,0.00000931228,0.000008286931,0.0009984851],"genre_scores_gemma":[0.0066717267,0.9914562,0.00028005883,0.00032130803,0.00028508835,0.000009879312,0.00003212855,0.00000173821,0.00094183016],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998877,0.000026563881,0.000016228034,0.000019315647,0.00003313393,0.00001704392],"domain_scores_gemma":[0.99990237,0.00003055882,0.000024798552,0.000003924898,0.000024151155,0.0000141706505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031913756,0.0006403133,0.0010068523,0.0016546116,0.00026059782,0.0008428395,0.0005752279,0.0011471595,0.0017146767],"category_scores_gemma":[0.00031911687,0.00017752156,0.00025983565,0.0009069463,0.000579762,0.0007956166,0.0005188796,0.00094830134,0.0010841804],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009973061,0.000061597835,0.00089565327,0.007406669,0.00006982613,0.0019598121,0.0001401842,0.00031238917,0.0049721114,0.0052948655,0.022221077,0.95656615],"study_design_scores_gemma":[0.000049599974,0.00011314829,0.003832128,0.0033178113,0.0001279102,0.030537328,0.00022219565,0.00017115705,0.0019184418,0.0049860016,0.95469534,0.000029040517],"about_ca_topic_score_codex":0.0009478967,"about_ca_topic_score_gemma":0.0012226932,"teacher_disagreement_score":0.0017146767,"about_ca_system_score_codex":0.00078390667,"about_ca_system_score_gemma":0.0006510699,"threshold_uncertainty_score":0.005736172},"labels":[],"label_agreement":null},{"id":"W2092820206","doi":"10.1172/jci18637","title":"Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-α–stimulated STAT2-independent production of IFN-γ in the brain","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; National Institutes of Health; York University; Multiple Sclerosis Society; National Institute of General Medical Sciences; National Institute of Mental Health","keywords":"STAT2; STAT protein; STAT1; Biology; Sonic hedgehog; Cancer research; Medulloblastoma; STAT4; Signal transduction; STAT6; Cell biology; Immune system; STAT3; Immunology; stat; Interleukin 4","score_opus":0.05882957799828798,"score_gpt":0.35636262239180294,"score_spread":0.29753304439351497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092820206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976683,0.00073173776,0.00064620015,0.000042644857,0.00001667514,0.000011202112,0.00025035298,0.00005067328,0.0005823319],"genre_scores_gemma":[0.9966744,0.0005684836,0.00061839394,0.000031893254,0.000008842494,0.000025057974,0.00047627022,0.000015434724,0.0015812981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998932,0.000010404656,0.000013059352,0.000026234547,0.000029399236,0.000027563798],"domain_scores_gemma":[0.9999188,0.0000057234142,0.00003401961,0.000008928928,0.000006013345,0.000026622303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007992725,0.00044025027,0.00020257666,0.00035161254,0.00012648929,0.00027234384,0.00014033244,0.00023174011,0.00071213854],"category_scores_gemma":[0.000069920025,0.00020713403,0.00024107783,0.000118257354,0.00041773467,0.00020120166,0.00020616244,0.00060413615,0.0002666268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016713771,0.000009291765,0.00043376314,0.000014846968,0.0000055570836,0.00023008739,0.000010261553,0.000027841199,0.99867344,0.00007497485,0.00001984199,0.0003329276],"study_design_scores_gemma":[0.000028100107,0.00021516015,0.022340022,0.0000083132945,0.000037469148,0.0022408657,0.00007096392,0.0007604592,0.97281533,0.0001914101,0.0012862671,0.000005627256],"about_ca_topic_score_codex":0.00071371475,"about_ca_topic_score_gemma":0.0010959478,"teacher_disagreement_score":0.00071371475,"about_ca_system_score_codex":0.00033695856,"about_ca_system_score_gemma":0.00024256566,"threshold_uncertainty_score":0.0024448037},"labels":[],"label_agreement":null},{"id":"W2093116780","doi":"10.1172/jci32479","title":"Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":284,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Vetenskapsrådet; Karolinska Institutet; European Commission; Rosalind Franklin University of Medicine and Science; Swedish Cancer Foundation; University of Toronto; Eli Lilly and Company","keywords":"Angiogenesis; Platelet-derived growth factor receptor; Metastasis; Neovascularization; Cancer research; Mural cell; Downregulation and upregulation; Fibroblast growth factor; Platelet-derived growth factor; Biology; Tumor progression; Growth factor; Medicine; Endocrinology; Internal medicine; Cancer; Receptor; Vascular smooth muscle; Biochemistry","score_opus":0.0413639383118473,"score_gpt":0.34187791536392365,"score_spread":0.30051397705207633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093116780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98181975,0.0075019714,0.004768322,0.00024217882,0.00008676566,0.000089613175,0.00019944791,0.00022625705,0.0050658397],"genre_scores_gemma":[0.9920427,0.0015316147,0.003667587,0.000045005865,0.00003759613,0.000051198218,0.0001750676,0.000016704882,0.002432457],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961025,0.00013455136,0.00001863668,0.00002633658,0.000112239,0.0000980087],"domain_scores_gemma":[0.99983954,0.000034013377,0.000027283146,0.000015356038,0.000011759024,0.00007195202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030679247,0.00047617874,0.00027588184,0.0003987842,0.00012625684,0.00018424532,0.00010307705,0.00018828078,0.0010303918],"category_scores_gemma":[0.00018833556,0.00014888078,0.00022520388,0.00012561845,0.00014721852,0.00013764387,0.00027238255,0.00037392517,0.0002416725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024249965,0.00010284712,0.00022237236,0.000037287107,0.000011014473,0.00009254233,0.0000102869535,0.00016619585,0.9959441,0.00014027135,0.00013529781,0.0028952567],"study_design_scores_gemma":[0.00007403772,0.002108094,0.0035411883,0.000009614552,0.000032252312,0.00069850835,0.000017875094,0.0021696235,0.98585886,0.00012703397,0.005356148,0.0000067773776],"about_ca_topic_score_codex":0.00053951895,"about_ca_topic_score_gemma":0.0012474706,"teacher_disagreement_score":0.0010303918,"about_ca_system_score_codex":0.00021516267,"about_ca_system_score_gemma":0.00020507064,"threshold_uncertainty_score":0.0034469962},"labels":[],"label_agreement":null},{"id":"W2095330988","doi":"10.1172/jci11321","title":"Fetal parathyroids are not required to maintain placental calcium transport","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Memorial University of Newfoundland","keywords":"Internal medicine; Endocrinology; Fetus; Parathyroid hormone; Parathyroid hormone-related protein; Calcium metabolism; Calcium; Placenta; Biology; Medicine; Pregnancy","score_opus":0.16073439034211534,"score_gpt":0.43283778678662305,"score_spread":0.2721033964445077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095330988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9826155,0.0035808866,0.009720265,0.00043625518,0.0000569253,0.000033189193,0.0009580281,0.00032749187,0.0022714217],"genre_scores_gemma":[0.99175465,0.001177545,0.0040812045,0.00008484769,0.00001769482,0.00004483448,0.00041296845,0.00006593078,0.0023602974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997465,0.000034664303,0.00002407156,0.00005228431,0.00010196007,0.000040442777],"domain_scores_gemma":[0.99949276,0.000098805445,0.00019966578,0.0000821436,0.000041297226,0.00008520869],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025945023,0.00028576222,0.00024651308,0.00032725278,0.00019909124,0.0004186476,0.00040510797,0.00052069494,0.0027241183],"category_scores_gemma":[0.000491686,0.0003062454,0.0002514657,0.00014445547,0.00053350057,0.00029924978,0.00030328063,0.0007337679,0.00049159414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025323292,0.0000125463375,0.00080085604,0.00005415675,0.000009185831,0.00035832572,0.00003400231,0.000058470247,0.99539256,0.00049176795,0.00006953134,0.002465439],"study_design_scores_gemma":[0.00018454209,0.0003656161,0.021700704,0.000034072655,0.000078117984,0.0052032885,0.000085548265,0.00074420916,0.9611061,0.00078721216,0.009694989,0.000015531106],"about_ca_topic_score_codex":0.00067319756,"about_ca_topic_score_gemma":0.00079519325,"teacher_disagreement_score":0.0027241183,"about_ca_system_score_codex":0.00027904488,"about_ca_system_score_gemma":0.0002779774,"threshold_uncertainty_score":0.009113073},"labels":[],"label_agreement":null},{"id":"W2095545431","doi":"10.1172/jci57414","title":"Dissecting the bulge in hair regeneration","year":2012,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; School of Medicine, New York University; Ellison Medical Foundation; York University; Dermatology Foundation","keywords":"Hair follicle; Stem cell; Regeneration (biology); Hair cycle; Biology; Cell biology; Adult stem cell; Melanocyte; Cellular differentiation; Genetics","score_opus":0.3043779786219467,"score_gpt":0.4871094002853221,"score_spread":0.18273142166337542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095545431","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016077526,0.9984242,0.00022595994,0.00022406898,0.00014360367,0.0000027696597,0.000003863093,0.000005905227,0.0008089193],"genre_scores_gemma":[0.0011976759,0.9975867,0.00032201014,0.0001824342,0.00015390156,0.000005127792,0.000007322736,0.0000015649132,0.00054329576],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998541,0.000027380767,0.0000198925,0.00002922121,0.000055327026,0.000014034375],"domain_scores_gemma":[0.99984646,0.000071546485,0.000022759672,0.0000058775317,0.000035436995,0.000017970846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004595748,0.00062128535,0.00096716103,0.0019571157,0.00035947765,0.0009205381,0.00070428784,0.0013678364,0.0020104484],"category_scores_gemma":[0.00043308022,0.00024375822,0.00040583502,0.0011632091,0.0011960377,0.0019649607,0.0007735913,0.0016257804,0.0018455524],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006702091,0.000061148894,0.00021161744,0.015497848,0.000041724583,0.0005603771,0.00014303127,0.00029273445,0.005177301,0.010544372,0.0150969,0.952306],"study_design_scores_gemma":[0.000017073127,0.00013088292,0.0014865524,0.0038190803,0.00006124422,0.0050823363,0.00025459987,0.00012248335,0.0020852117,0.00646673,0.9804401,0.00003382337],"about_ca_topic_score_codex":0.0007183316,"about_ca_topic_score_gemma":0.0011484524,"teacher_disagreement_score":0.0020104484,"about_ca_system_score_codex":0.0005487355,"about_ca_system_score_gemma":0.0007043653,"threshold_uncertainty_score":0.0067255497},"labels":[],"label_agreement":null},{"id":"W2096018298","doi":"10.1172/jci17974","title":"Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":842,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Christie (Canada)","funders":"Wellcome Trust; GlaxoSmithKline","keywords":"Periostin; Eosinophil; Basement membrane; Lumican; Eosinophil cationic protein; Medicine; Asthma; Immunology; Pathology; Extracellular matrix; Interleukin 5; Bronchoalveolar lavage; Interleukin; Decorin; Internal medicine; Biology; Lung; Cytokine; Proteoglycan; Cell biology","score_opus":0.06907356681266541,"score_gpt":0.36392874154126686,"score_spread":0.29485517472860145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096018298","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99741447,0.0021682507,0.00013319933,0.000058281057,0.000026833726,0.000035252728,0.000026664342,0.000016710164,0.00012019782],"genre_scores_gemma":[0.99828315,0.0007700413,0.00027495113,0.00011680586,0.000049345967,0.00004760709,0.00007622879,0.0000027240194,0.00037914782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997893,0.00006830309,0.00002351966,0.00002570052,0.000044474626,0.000048796137],"domain_scores_gemma":[0.99973434,0.000047818638,0.00007780919,0.000013681325,0.000021533764,0.00010480711],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035132858,0.00039429756,0.001212634,0.00019831973,0.00024840102,0.000281775,0.0002566778,0.00046314936,0.0008927479],"category_scores_gemma":[0.00039678073,0.00021499574,0.0003077114,0.00008042789,0.00025669616,0.00020158167,0.00014835644,0.0008013681,0.00015721904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06841872,0.0071959496,0.01360273,0.00063506153,0.00036115712,0.0005068466,0.00016020221,0.00029309088,0.83743876,0.000056295823,0.00040533772,0.07092585],"study_design_scores_gemma":[0.01757169,0.3020492,0.5097213,0.0001174649,0.0013155456,0.0015519637,0.0002974625,0.0018814505,0.16008686,0.00014735154,0.0052120835,0.000047779777],"about_ca_topic_score_codex":0.00040369813,"about_ca_topic_score_gemma":0.0008990754,"teacher_disagreement_score":0.001212634,"about_ca_system_score_codex":0.00018620979,"about_ca_system_score_gemma":0.00015484454,"threshold_uncertainty_score":0.0029865503},"labels":[],"label_agreement":null},{"id":"W2096171994","doi":"10.1172/jci58577","title":"Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":332,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; McMaster University; Canadian Diabetes Association","keywords":"Insulin resistance; Adipose tissue; Endocrinology; Internal medicine; AMPK; Inflammation; Bone marrow; Adipose tissue macrophages; Macrophage; Biology; Insulin; Chemistry; Medicine; Biochemistry; Protein kinase A; Phosphorylation; In vitro","score_opus":0.04141721394672844,"score_gpt":0.3166748931433048,"score_spread":0.2752576791965764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096171994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921313,0.0020979804,0.002651614,0.00046451957,0.0000850517,0.000045714147,0.0004965754,0.0002116397,0.001815699],"genre_scores_gemma":[0.9859504,0.0023098649,0.0038993172,0.0002853872,0.000033273427,0.00011493797,0.00070699386,0.00011021561,0.006589688],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977595,0.000054865854,0.00002515996,0.000034564775,0.000051203016,0.000058193844],"domain_scores_gemma":[0.99979526,0.000021912769,0.00006810212,0.000025038034,0.000016166172,0.00007349213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023045641,0.0004452055,0.00041202322,0.00056704134,0.00019879342,0.0003806208,0.00029004522,0.00043121408,0.0022779861],"category_scores_gemma":[0.00014968945,0.00030017103,0.00024262023,0.00027188592,0.00041631487,0.0002130764,0.00024025587,0.0012509277,0.00054633716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007399815,0.0002159122,0.00014918536,0.000036093596,0.00000823116,0.000028310824,0.000014822872,0.00008132692,0.9970222,0.00014472204,0.000072810384,0.0014863358],"study_design_scores_gemma":[0.00018915514,0.0015148778,0.003009488,0.000023173727,0.00003777374,0.00021100794,0.000050007777,0.0006695172,0.99188846,0.00017238053,0.002227338,0.0000067929573],"about_ca_topic_score_codex":0.00033110657,"about_ca_topic_score_gemma":0.00059333054,"teacher_disagreement_score":0.0022779861,"about_ca_system_score_codex":0.00021413773,"about_ca_system_score_gemma":0.0002796793,"threshold_uncertainty_score":0.0076206923},"labels":[],"label_agreement":null},{"id":"W2096190607","doi":"10.1172/jci41062","title":"N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":245,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; University of Toronto","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Heart and Stroke Foundation of Canada; American Heart Association","keywords":"ADAMTS13; Von Willebrand factor; Chemistry; Acetylcysteine; Platelet; Thrombotic thrombocytopenic purpura; Mucin; Pharmacology; Molecular biology; Biochemistry; Immunology; Medicine","score_opus":0.1126297699523004,"score_gpt":0.35687517591966617,"score_spread":0.24424540596736577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096190607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871824,0.005847291,0.0030892326,0.0004951956,0.00015083971,0.00009931075,0.00049469265,0.00022768733,0.0024134596],"genre_scores_gemma":[0.9900031,0.0023577474,0.0026934934,0.00021536165,0.000036481983,0.00009151124,0.0005018086,0.000027409083,0.0040731207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975246,0.00007319996,0.000029885183,0.000043226177,0.000057381494,0.00004390748],"domain_scores_gemma":[0.9998447,0.000020603422,0.00004694004,0.000017330127,0.000018336672,0.000052067167],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027746562,0.00046972072,0.00025807504,0.00042908,0.0001259943,0.00022210018,0.0002657459,0.00058231445,0.001137034],"category_scores_gemma":[0.00022187414,0.00020526451,0.00032405625,0.00013716865,0.00023566395,0.0002051338,0.0001276121,0.0006712487,0.0002362421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067137333,0.00024255684,0.00014925248,0.00006905285,0.000019555444,0.00006625831,0.000019711655,0.000048116133,0.99580187,0.00013390215,0.00014278803,0.0026355763],"study_design_scores_gemma":[0.00016658305,0.0035909798,0.0045095193,0.00001598722,0.00006825643,0.0003494811,0.000023228773,0.0010580441,0.9854504,0.0001152264,0.004643866,0.000008396521],"about_ca_topic_score_codex":0.00058225257,"about_ca_topic_score_gemma":0.00064722245,"teacher_disagreement_score":0.001137034,"about_ca_system_score_codex":0.0002349758,"about_ca_system_score_gemma":0.00024558927,"threshold_uncertainty_score":0.0038037896},"labels":[],"label_agreement":null},{"id":"W2096574031","doi":"10.1172/jci31986","title":"Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":391,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Obesity Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American Diabetes Association; University of Kentucky; American Heart Association; National Institutes of Health","keywords":"Osteopontin; Adipose tissue; Adipose tissue macrophages; Inflammation; Insulin resistance; Internal medicine; Endocrinology; Proinflammatory cytokine; Stromal vascular fraction; Monocyte; Biology; White adipose tissue; Insulin; Medicine","score_opus":0.05055817701367395,"score_gpt":0.3662460256308562,"score_spread":0.31568784861718224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096574031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98942405,0.0023754905,0.005306548,0.0005729468,0.000072848605,0.000088929715,0.00042464267,0.00019861863,0.0015358594],"genre_scores_gemma":[0.9851576,0.0026836481,0.0047158664,0.00036690463,0.000050813316,0.00030042496,0.00069604523,0.00014378314,0.005884869],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994815,0.00012610035,0.000043027838,0.000111739064,0.00011772972,0.00011990253],"domain_scores_gemma":[0.9995328,0.000043085278,0.0001895033,0.000044639964,0.000028506516,0.00016149718],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000541158,0.0007676731,0.00049035583,0.0010727932,0.000300803,0.0006232053,0.00046062193,0.0008115948,0.0021221794],"category_scores_gemma":[0.00030405534,0.0005777954,0.0004691786,0.0002803494,0.00065744587,0.0004727039,0.0006247116,0.0019019318,0.0007931938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007888152,0.00024370865,0.00044556588,0.000048824862,0.000013287014,0.00016912258,0.000044636014,0.00006801137,0.99599516,0.00033377836,0.000094422736,0.0017545568],"study_design_scores_gemma":[0.0012433544,0.004230421,0.024570946,0.00015508238,0.00019557735,0.0024058213,0.00026572988,0.0048393076,0.9489071,0.001335629,0.011805593,0.000045448967],"about_ca_topic_score_codex":0.0005941038,"about_ca_topic_score_gemma":0.00091658044,"teacher_disagreement_score":0.0021221794,"about_ca_system_score_codex":0.0004647904,"about_ca_system_score_gemma":0.00032633962,"threshold_uncertainty_score":0.0070994496},"labels":[],"label_agreement":null},{"id":"W2096797731","doi":"10.1172/jci82267","title":"Rabbit antithymocyte globulin–induced serum sickness disease and human kidney graft survival","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba","funders":"Université de Nantes; Ministère de l'Enseignement Supérieur et de la Recherche; Conseil Régional des Pays de la Loire; Agence Nationale de la Recherche","keywords":"Serum sickness; Globulin; Immunology; Medicine; Kidney; Disease; Antibody; Internal medicine","score_opus":0.1567428427380242,"score_gpt":0.4196775259272789,"score_spread":0.2629346831892547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096797731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99908185,0.00055326754,0.000061076425,0.000012648626,0.0000024459312,0.0000019772876,0.00009391188,0.0000024876829,0.00019027127],"genre_scores_gemma":[0.9997148,0.000070221955,0.00002842613,0.0000061251562,0.0000028296504,0.0000016508194,0.00013348844,4.702e-7,0.00004197365],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997235,0.00006986165,0.000044583423,0.00004650901,0.000070573755,0.000045041124],"domain_scores_gemma":[0.99847597,0.00032937434,0.00085715327,0.00007208745,0.000096744865,0.00016868935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007401099,0.00014294453,0.00019542802,0.0005315768,0.00012962762,0.00031666536,0.00014239423,0.00018260811,0.0011558435],"category_scores_gemma":[0.0010711291,0.000051622817,0.00024460148,0.0004689425,0.0002144577,0.00015140444,0.00021310302,0.00025078573,0.00014530576],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005577856,0.000026306914,0.9956696,0.0000186375,0.000051909567,0.00006843116,0.000027465958,0.000058018864,0.0014776295,0.000017602655,0.000048234746,0.001978462],"study_design_scores_gemma":[0.00001008271,0.0002809668,0.99734074,0.0000073766682,0.000050945633,0.00073387177,0.000036973463,0.00023635692,0.000978165,0.000027434662,0.00029498502,0.0000020345142],"about_ca_topic_score_codex":0.0006107981,"about_ca_topic_score_gemma":0.0004983983,"teacher_disagreement_score":0.0011558435,"about_ca_system_score_codex":0.00025839388,"about_ca_system_score_gemma":0.0002426177,"threshold_uncertainty_score":0.003914118},"labels":[],"label_agreement":null},{"id":"W2097061706","doi":"10.1172/jci15748","title":"Increased ABCA1 activity protects against atherosclerosis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":250,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia; BC Children's Hospital; Xenon Pharmaceuticals (Canada); Children's & Women's Health Centre of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"ABCA1; Efflux; Cholesterol; Reverse cholesterol transport; Apolipoprotein E; Genetically modified mouse; Phospholipid; Transgene; Endocrinology; Chemistry; In vivo; Transporter; Internal medicine; Biology; Lipoprotein; Biochemistry; Medicine; Gene; Genetics","score_opus":0.14440987041581818,"score_gpt":0.35980648760842343,"score_spread":0.21539661719260525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097061706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99191535,0.0042450805,0.0008728858,0.00051153527,0.00015845726,0.00002354361,0.00026174414,0.00027236558,0.0017390085],"genre_scores_gemma":[0.99301285,0.0022860777,0.00044585814,0.00022555247,0.000100989964,0.000034507353,0.0006615717,0.000030133117,0.0032025937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978024,0.000052091473,0.00002080717,0.00002928849,0.00004336868,0.00007410232],"domain_scores_gemma":[0.9996253,0.000042341082,0.00007302876,0.00007871735,0.000047319747,0.00013323626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030090168,0.00040378628,0.00097307406,0.00038580902,0.00019439081,0.00044462108,0.0002891016,0.00049435673,0.0032401308],"category_scores_gemma":[0.00034115647,0.00023108105,0.0002656471,0.00022475641,0.00029976177,0.0002586512,0.0002641827,0.0014897855,0.00076126127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040562022,0.0011341452,0.0010970399,0.00014133813,0.00009324469,0.00017586391,0.000030276911,0.00011967729,0.97279626,0.00036587217,0.000955041,0.019034993],"study_design_scores_gemma":[0.0024275114,0.032481633,0.05936618,0.00010491686,0.0005810097,0.0023505776,0.00014910355,0.001878715,0.8778213,0.0011203989,0.021658087,0.000060575],"about_ca_topic_score_codex":0.00036887667,"about_ca_topic_score_gemma":0.00033917325,"teacher_disagreement_score":0.0032401308,"about_ca_system_score_codex":0.0001788971,"about_ca_system_score_gemma":0.00021900832,"threshold_uncertainty_score":0.010839343},"labels":[],"label_agreement":null},{"id":"W2097135837","doi":"10.1172/jci26032","title":"Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor- viral RNA interactions","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":661,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Center for AIDS Research, University of Washington; York University; Wellcome Trust; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; National Cancer Institute; School of Medicine, New York University; National Institutes of Health; Yale University; Cancer Research Institute","keywords":"TLR7; TLR3; RNA; Biology; Endosome; Viral envelope; Endocytosis; Plasmacytoid dendritic cell; Cell biology; Interferon; Toll-like receptor; Virology; Virus; Innate immune system; Immune system; Receptor; Dendritic cell; Immunology; Gene; Genetics; Intracellular","score_opus":0.05002535495958479,"score_gpt":0.3543757530537523,"score_spread":0.30435039809416753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097135837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853989,0.004151509,0.0060669994,0.0002651387,0.00004323897,0.000064307955,0.00023940954,0.00010921588,0.0036612719],"genre_scores_gemma":[0.99231553,0.0019509832,0.0035452773,0.00009498522,0.000022164872,0.000033931876,0.00025195605,0.000010166299,0.0017749578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980587,0.00003906113,0.000011451,0.000024667943,0.000060200186,0.000058848793],"domain_scores_gemma":[0.9999387,0.000021822749,0.00000984212,0.000007742086,0.000009617869,0.000012179699],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001300983,0.00030196813,0.0002698077,0.00018129671,0.00019897509,0.00045917722,0.0001444669,0.00032769458,0.0010270939],"category_scores_gemma":[0.00014510998,0.00017079867,0.00039987487,0.000103762744,0.00014020738,0.00023763845,0.00037152937,0.0004422543,0.00051866006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009976235,0.000018616309,0.0002944713,0.0000549529,0.00000641539,0.000107214284,0.000016954593,0.000119436794,0.99636865,0.0002954274,0.000066986475,0.0025511116],"study_design_scores_gemma":[0.000050675717,0.0001939922,0.0039967624,0.000012699946,0.00001779287,0.0005218345,0.00004493282,0.0026710227,0.98801196,0.00036199714,0.004109377,0.0000069708058],"about_ca_topic_score_codex":0.00028792594,"about_ca_topic_score_gemma":0.00035369914,"teacher_disagreement_score":0.0010270939,"about_ca_system_score_codex":0.0006020138,"about_ca_system_score_gemma":0.00032456548,"threshold_uncertainty_score":0.004367888},"labels":[],"label_agreement":null},{"id":"W2097141045","doi":"10.1172/jci71090","title":"Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital Diaphragmatic Hernia Studies","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Heparan sulfate; Biology; Congenital diaphragmatic hernia; Perlecan; Cell biology; Angiogenesis; Knockout mouse; Cancer research; Immunology; Internal medicine; Receptor; Genetics; Biochemistry; Medicine; Heparin","score_opus":0.06549491272047092,"score_gpt":0.3483720094520007,"score_spread":0.2828770967315298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097141045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99846905,0.000607696,0.00050887634,0.000036685335,0.000005951356,0.000006269726,0.000056470868,0.000013392711,0.00029556104],"genre_scores_gemma":[0.9986505,0.0004499349,0.00043746436,0.000014249364,0.0000029997345,0.0000050924673,0.00006625827,0.0000028568825,0.00037069537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999225,0.00002250558,0.000009575339,0.000012850053,0.000018646168,0.000014023134],"domain_scores_gemma":[0.9999114,0.000016325997,0.000035737015,0.000006106505,0.0000043921386,0.00002601488],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009770748,0.0001919901,0.00013050422,0.00018065686,0.0000807435,0.000111852256,0.00009465693,0.00017490318,0.0005575027],"category_scores_gemma":[0.000119176664,0.00008877234,0.000095403266,0.000070872455,0.00024061603,0.00008465792,0.00015800279,0.00026943008,0.000059464135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019631174,0.000043172156,0.002669259,0.000053284875,0.0000113405695,0.00064747303,0.00002221706,0.00009095634,0.99281913,0.00013505452,0.00004725517,0.003264493],"study_design_scores_gemma":[0.00005722105,0.0009704492,0.0755243,0.000018469374,0.00004683269,0.0060784873,0.00010240796,0.0014071262,0.912765,0.0001372545,0.0028849018,0.0000076010033],"about_ca_topic_score_codex":0.00032370051,"about_ca_topic_score_gemma":0.0007092083,"teacher_disagreement_score":0.0005575027,"about_ca_system_score_codex":0.00018798375,"about_ca_system_score_gemma":0.0001632029,"threshold_uncertainty_score":0.0018650889},"labels":[],"label_agreement":null},{"id":"W2097216924","doi":"10.1172/jci31350","title":"KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"York University; National Cancer Institute; National Institutes of Health; Cancer Research Institute; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Antigen; MHC class I; Antigen presentation; Biology; Cytotoxic T cell; Major histocompatibility complex; CD8; Immunology; Epitope; Cancer immunotherapy; Listeria monocytogenes; T cell; Immune system; Immunotherapy; In vitro","score_opus":0.1338904788240948,"score_gpt":0.3803547236159111,"score_spread":0.2464642447918163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097216924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93776995,0.016118519,0.037542902,0.00062721776,0.0003515411,0.00026570787,0.00097198336,0.0009557933,0.0053963796],"genre_scores_gemma":[0.9752273,0.0035139513,0.013639974,0.00012102223,0.000040646108,0.00013439229,0.0013668054,0.000049940434,0.0059058135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998429,0.00003147369,0.00001836923,0.00003062848,0.000047329595,0.000029351984],"domain_scores_gemma":[0.9999429,0.0000070797864,0.000018935907,0.000007989625,0.000008233996,0.000014871086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015319604,0.00035494287,0.00020767191,0.00024904747,0.00011820391,0.00034250252,0.00018879601,0.0003393482,0.0010379857],"category_scores_gemma":[0.000108579625,0.00016406496,0.00014843157,0.0001416636,0.00018084608,0.00022867144,0.00021990095,0.0007330226,0.00054716103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011759171,0.000065226195,0.00017564814,0.00008459924,0.0000049892874,0.000048241094,0.000010977799,0.0000730138,0.9927729,0.00022133856,0.00015838839,0.006267077],"study_design_scores_gemma":[0.00009494603,0.0014395539,0.0020737674,0.000029230085,0.0000395074,0.0008329489,0.00001537454,0.0012625145,0.97360444,0.000101494516,0.020492498,0.000013844708],"about_ca_topic_score_codex":0.00024389212,"about_ca_topic_score_gemma":0.0002040953,"teacher_disagreement_score":0.0010379857,"about_ca_system_score_codex":0.00025838945,"about_ca_system_score_gemma":0.00024416484,"threshold_uncertainty_score":0.0034723878},"labels":[],"label_agreement":null},{"id":"W2097448914","doi":"10.1172/jci25509","title":"Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":527,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Neurogenesis; Dentate gyrus; Hippocampal formation; Neuroscience; Cannabinoid receptor; Anxiolytic; Neural stem cell; Hippocampus; Cannabinoid; Pharmacology; Biology; Medicine; Stem cell; Internal medicine; Receptor; Cell biology; Agonist","score_opus":0.02596151156862688,"score_gpt":0.3436696183526028,"score_spread":0.31770810678397593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097448914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916011,0.00455394,0.0005399383,0.00006954145,0.0000158339,0.000025591266,0.00018689547,0.000040006493,0.0029671076],"genre_scores_gemma":[0.9922516,0.0039950735,0.0012193889,0.000054956057,0.000016487304,0.000021451247,0.00018891551,0.0000047428084,0.002247485],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999678,0.0000043415534,0.000002986311,0.0000035353949,0.000010680632,0.0000106125035],"domain_scores_gemma":[0.99996614,0.0000043596024,0.000008817715,0.000002854833,0.0000027807444,0.000015028936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054638702,0.00019508677,0.00012101074,0.00015889706,0.000093382056,0.0001026725,0.00008025107,0.0000985612,0.0016528529],"category_scores_gemma":[0.00008856375,0.00007091971,0.00009400524,0.00008504607,0.00015027137,0.00008676102,0.00013171238,0.000224067,0.0002552195],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073163555,0.00015580287,0.0006478175,0.00011321882,0.000010802132,0.00014423503,0.000028746601,0.000049689806,0.9784622,0.00025984645,0.000133745,0.019262273],"study_design_scores_gemma":[0.00017290076,0.002233868,0.037574664,0.000034567587,0.0000402998,0.0005997199,0.00007163383,0.00032732356,0.95169973,0.0002111202,0.007026403,0.000007762372],"about_ca_topic_score_codex":0.00062794256,"about_ca_topic_score_gemma":0.0020745983,"teacher_disagreement_score":0.0016528529,"about_ca_system_score_codex":0.0001399213,"about_ca_system_score_gemma":0.00014997019,"threshold_uncertainty_score":0.0055294037},"labels":[],"label_agreement":null},{"id":"W2097573911","doi":"10.1172/jci32959","title":"Recovery from diabetes in mice by β cell regeneration","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":597,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Hebrew University of Jerusalem","keywords":"Beta cell; Neogenesis; Regeneration (biology); Islet; Doxycycline; Biology; Glucose homeostasis; Immunology; Transplantation; Diabetes mellitus; Stem cell; Endocrinology; Cell biology; Internal medicine; Cancer research; Insulin resistance; Pharmacology; Medicine; Antibiotics; Biochemistry","score_opus":0.05160187478631977,"score_gpt":0.3345719929995159,"score_spread":0.2829701182131961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097573911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91991,0.008944889,0.03673015,0.0030311667,0.0005647607,0.00070951873,0.005594465,0.006894559,0.017620482],"genre_scores_gemma":[0.8741854,0.009803822,0.053906195,0.0018664523,0.0002621877,0.0022097363,0.008285433,0.0016322159,0.047848452],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992256,0.00011857408,0.00012723981,0.00017577976,0.0001729346,0.00017987104],"domain_scores_gemma":[0.99925345,0.00010145924,0.00025052633,0.00012709867,0.00004939374,0.00021798407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009838167,0.0013405943,0.00076723134,0.0023972301,0.000598007,0.0010064207,0.0009078762,0.001698416,0.0053158705],"category_scores_gemma":[0.00038770892,0.0008395563,0.0009541007,0.00048856984,0.00085403176,0.0009862488,0.00081672595,0.0030930864,0.0025790061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001168125,0.0005986745,0.00035021696,0.00017036598,0.000030051771,0.00031528683,0.00012032487,0.00029178598,0.9822843,0.0020943775,0.0007524251,0.011823899],"study_design_scores_gemma":[0.0010713852,0.0039076395,0.005210931,0.00020737469,0.000112664464,0.00294152,0.00012977299,0.0041943006,0.93970203,0.0023993542,0.04005935,0.000063664345],"about_ca_topic_score_codex":0.0004516724,"about_ca_topic_score_gemma":0.0007362289,"teacher_disagreement_score":0.0053158705,"about_ca_system_score_codex":0.00053589954,"about_ca_system_score_gemma":0.00052919064,"threshold_uncertainty_score":0.017783344},"labels":[],"label_agreement":null},{"id":"W2097830796","doi":"10.1172/jci77820","title":"Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canadian Blood Services; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; University of Toronto; Canadian Blood Services; Heart and Stroke Foundation of Canada","keywords":"Neonatal alloimmune thrombocytopenia; Angiogenesis; Medicine; Integrin; Immunology; Fetus; Antibody; Hemostasis; Antigen; Platelet; Biology; Internal medicine; Pregnancy; Receptor","score_opus":0.08439889918890468,"score_gpt":0.36833575572728117,"score_spread":0.28393685653837647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097830796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949255,0.0018702724,0.0017437877,0.0001073687,0.000028761277,0.000021497446,0.00014863005,0.00006479253,0.0010893847],"genre_scores_gemma":[0.99535936,0.0019010428,0.0011418626,0.00010394987,0.000013698339,0.000056007753,0.00018176094,0.000012090309,0.0012303905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998388,0.000035900906,0.000018393239,0.000027183214,0.000041280844,0.000038464368],"domain_scores_gemma":[0.9998416,0.000046257264,0.000055218115,0.000016420508,0.000009660708,0.00003084894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015567479,0.00036961836,0.00024197155,0.0002190735,0.00009146294,0.00015793831,0.00019914325,0.0003250306,0.0008649844],"category_scores_gemma":[0.00035206904,0.0001117595,0.0002378978,0.0000904787,0.00020027508,0.000112465714,0.00016164272,0.00053980394,0.00013529767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050010136,0.00013241576,0.0013228564,0.00008544758,0.000022908856,0.0009011815,0.0000695173,0.00011676583,0.98988134,0.00032067072,0.00016246617,0.0064843684],"study_design_scores_gemma":[0.000104230196,0.0030003157,0.032998882,0.000037483136,0.0001094036,0.004038675,0.00014726174,0.0018355489,0.95252514,0.00033048843,0.00485977,0.000012817276],"about_ca_topic_score_codex":0.00080173934,"about_ca_topic_score_gemma":0.000892164,"teacher_disagreement_score":0.0008649844,"about_ca_system_score_codex":0.00025878195,"about_ca_system_score_gemma":0.00021145125,"threshold_uncertainty_score":0.0028936267},"labels":[],"label_agreement":null},{"id":"W2098161615","doi":"10.1172/jci41036","title":"Health care reform — need for less emotion and more science","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Primary Care and Health Outcomes","field":"Health Professions","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Health care; Government (linguistics); Quality (philosophy); Public relations; Value (mathematics); Health care reform; Medicine; Business; Health policy; Political science; Economic growth; Economics","score_opus":0.2256484099517937,"score_gpt":0.5621515260264938,"score_spread":0.33650311607470007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098161615","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00088603754,0.0037812106,0.0002247777,0.9910563,0.0014746211,0.0000033976528,0.0000066732687,0.00000877618,0.0025581657],"genre_scores_gemma":[0.10989921,0.011987657,0.0015292829,0.8509348,0.021984784,0.00005349343,0.000035553683,0.00003586166,0.003539298],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98843646,0.0069698486,0.00028711103,0.0006195681,0.0021739688,0.0015130236],"domain_scores_gemma":[0.9598799,0.019413384,0.002860867,0.0012626288,0.0036045026,0.012978666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01959768,0.0004760031,0.0011814467,0.0012050138,0.0058655827,0.0119277835,0.0017154808,0.01534981,0.010465648],"category_scores_gemma":[0.02608343,0.0002560616,0.0006574569,0.0010552453,0.023407156,0.013163604,0.0074007055,0.021211395,0.0013728203],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016977193,0.00041981705,0.0022918438,0.001006795,0.00010495166,0.00037811633,0.0067128753,0.00028549175,0.0010444071,0.33685794,0.5336877,0.11704038],"study_design_scores_gemma":[0.00028930354,0.00022618467,0.0047686608,0.0019306798,0.000046450925,0.0004386561,0.021955874,0.0004989399,0.0003304144,0.35033897,0.6190845,0.00009141851],"about_ca_topic_score_codex":0.0022284512,"about_ca_topic_score_gemma":0.0030281446,"teacher_disagreement_score":0.01959768,"about_ca_system_score_codex":0.006529125,"about_ca_system_score_gemma":0.014866023,"threshold_uncertainty_score":0.103643656},"labels":[],"label_agreement":null},{"id":"W2098195823","doi":"10.1172/jci19159","title":"Autosomal dominant pseudohypoparathyroidism type Ib is associated with a heterozygous microdeletion that likely disrupts a putative imprinting control element of GNAS","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":259,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital; McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health","keywords":"GNAS complex locus; Pseudohypoparathyroidism; Exon; Genetics; Genomic imprinting; Biology; Locus (genetics); X chromosome; Imprinting (psychology); X-inactivation; Differentially methylated regions; DNA methylation; Molecular biology; Gene; Parathyroid hormone; Internal medicine; Medicine","score_opus":0.038505553832486036,"score_gpt":0.3210772784450016,"score_spread":0.28257172461251556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098195823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988651,0.00019912295,0.00037034744,0.00001788052,0.0000042682027,0.000009838944,0.00008068899,0.000022916429,0.00042971116],"genre_scores_gemma":[0.9987876,0.00013383235,0.00046019204,0.000021996637,0.000011618904,0.00000895486,0.00017098396,0.000006389371,0.00039840167],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99984884,0.00001881726,0.000017996219,0.00004933954,0.0000362438,0.00002876605],"domain_scores_gemma":[0.9997192,0.000056318135,0.00012104678,0.000020114525,0.000013909505,0.00006931339],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000068247115,0.00072401634,0.00028471331,0.00075826206,0.00037969372,0.00018349619,0.0003034877,0.00043813893,0.0017810176],"category_scores_gemma":[0.00044248623,0.0002660197,0.00021910336,0.00054215395,0.0004313078,0.00011350767,0.0003694003,0.00024192173,0.00025876123],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015989958,0.00020416827,0.4231416,0.0002508847,0.0003486531,0.12917867,0.0007830288,0.0002031918,0.41867533,0.0004879853,0.00058730406,0.024540171],"study_design_scores_gemma":[0.00008513054,0.00055995776,0.72587705,0.00001554237,0.00014810401,0.25852972,0.0001772218,0.00030313482,0.011885697,0.00018478712,0.0022152737,0.000018324989],"about_ca_topic_score_codex":0.001068343,"about_ca_topic_score_gemma":0.0016182123,"teacher_disagreement_score":0.0017810176,"about_ca_system_score_codex":0.00020162994,"about_ca_system_score_gemma":0.0001269602,"threshold_uncertainty_score":0.0059580803},"labels":[],"label_agreement":null},{"id":"W2098613222","doi":"10.1172/jci43343","title":"Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Ministerio de Educación y Cultura; Cardiff University; University of Oxford","keywords":"C3-convertase; Complement system; Alternative complement pathway; Proteases; Factor H; Mesangium; Pathogenesis; Complement factor I; Proteolysis; Mutant; Chemistry; Cell biology; Biology; Biochemistry; Immunology; Glomerulonephritis; Gene; Endocrinology; Enzyme; Kidney; Immune system","score_opus":0.056564546830934606,"score_gpt":0.3484637271839726,"score_spread":0.291899180353038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098613222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944102,0.0014639467,0.0025030277,0.00014418496,0.000020519636,0.000020549678,0.00031081552,0.00007561914,0.0010510674],"genre_scores_gemma":[0.9972938,0.00048051492,0.0015060285,0.000057361307,0.000009846821,0.000006129957,0.00021067068,0.000012761582,0.0004229114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991477,0.0000107648975,0.000007646206,0.000027358623,0.000026365338,0.000013169884],"domain_scores_gemma":[0.99993205,0.000014644521,0.000018051194,0.000008721771,0.000009627385,0.000016906306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011460123,0.00048107642,0.00020273241,0.00039815597,0.00019450819,0.00018426834,0.00018037783,0.0006744418,0.0010869012],"category_scores_gemma":[0.00018594401,0.000114381895,0.00025989983,0.00029274027,0.0002810302,0.000099542085,0.00020251276,0.00033103777,0.00023902253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057816145,0.000047229285,0.0075790347,0.000051735657,0.000033077176,0.0044225827,0.00006634057,0.00017765837,0.97823584,0.00045366542,0.00026705157,0.008087538],"study_design_scores_gemma":[0.00016799306,0.0010288331,0.17141618,0.00007132518,0.00020135609,0.118840426,0.00011672817,0.005864879,0.6888035,0.001388107,0.012033078,0.00006760162],"about_ca_topic_score_codex":0.0021464056,"about_ca_topic_score_gemma":0.0012106403,"teacher_disagreement_score":0.0021464056,"about_ca_system_score_codex":0.00030451283,"about_ca_system_score_gemma":0.00018902027,"threshold_uncertainty_score":0.0042678714},"labels":[],"label_agreement":null},{"id":"W2098735224","doi":"10.1172/jci71544","title":"Immune cell trafficking from the brain maintains CNS immune tolerance","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Global Health Research","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Immune system; Fingolimod; Neuroinflammation; Experimental autoimmune encephalomyelitis; Immunology; Multiple sclerosis; Biology; Microglia; Medicine; Inflammation","score_opus":0.07793008327191302,"score_gpt":0.32876903808784136,"score_spread":0.25083895481592833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098735224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98044956,0.006915146,0.0078709535,0.00039687267,0.000059076778,0.000045408793,0.00012488414,0.00016278846,0.003975382],"genre_scores_gemma":[0.98509914,0.0045808386,0.0077426787,0.0001778445,0.00005720312,0.00004105117,0.00016009081,0.000026385263,0.002114732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987936,0.00001620405,0.000009837331,0.00003231818,0.000025857751,0.000036396377],"domain_scores_gemma":[0.9999306,0.000006636557,0.000021598466,0.000011174158,0.000014376844,0.00001555694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014209666,0.00026821677,0.00041729168,0.00028821352,0.00035164892,0.00067181094,0.00022508562,0.0003017851,0.0007497954],"category_scores_gemma":[0.00013786046,0.00008260446,0.000208266,0.000112654205,0.00034200394,0.000371114,0.00030422988,0.0006145724,0.0003430947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012853094,0.000034525674,0.0005618543,0.00006451008,0.0000059727904,0.00017520029,0.000041257405,0.00007725581,0.9855479,0.0007847624,0.00010098502,0.0124772545],"study_design_scores_gemma":[0.000047413767,0.00081241474,0.009936609,0.00008205141,0.000053236487,0.0017083192,0.0002130392,0.0011345269,0.9692541,0.0010813618,0.015661826,0.000015097603],"about_ca_topic_score_codex":0.0003677408,"about_ca_topic_score_gemma":0.0007784428,"teacher_disagreement_score":0.0007497954,"about_ca_system_score_codex":0.00028449652,"about_ca_system_score_gemma":0.0005924756,"threshold_uncertainty_score":0.0025083423},"labels":[],"label_agreement":null},{"id":"W2099259456","doi":"10.1172/jci81859","title":"IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Associazione Italiana per la Ricerca sul Cancro; Novo Nordisk; CSL Behring; Ministero della Salute; Pfizer; McMaster University; Biogen","keywords":"TLR9; Immune tolerance; Immunology; Medicine; Antibody; Clotting factor; Internal medicine; Immune system; Pharmacology; Biology; Gene expression; Gene; Biochemistry","score_opus":0.18521686125478415,"score_gpt":0.4139520817657737,"score_spread":0.22873522051098955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099259456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99893945,0.00029684405,0.00049595744,0.00002235357,0.0000051510037,0.000006171027,0.000044166212,0.000014275033,0.00017563759],"genre_scores_gemma":[0.9992537,0.000115428724,0.00023488585,0.000009934767,0.000003663608,0.0000053561193,0.000071550785,0.0000027738938,0.00030272728],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999144,0.000026218147,0.000004584107,0.000012611605,0.000019615278,0.000022585877],"domain_scores_gemma":[0.99986684,0.000021441325,0.000047131365,0.000010289131,0.0000075367766,0.000046797515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015088877,0.00012866755,0.0002660983,0.00014268428,0.000075837765,0.00022422175,0.000083495164,0.0000751024,0.0005446886],"category_scores_gemma":[0.00027172474,0.00004976486,0.00013692088,0.0000909237,0.00010764068,0.00006863486,0.00011426242,0.00033651863,0.000078519086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020025866,0.002494303,0.06787141,0.00009256056,0.00014102404,0.00022746986,0.000100022575,0.0011137769,0.8359656,0.00028160276,0.00060350855,0.071082935],"study_design_scores_gemma":[0.0006029917,0.02871487,0.43707633,0.000025448393,0.00030877267,0.0012482147,0.0001888006,0.022184025,0.5013728,0.00033028683,0.007924834,0.000022622251],"about_ca_topic_score_codex":0.00038658732,"about_ca_topic_score_gemma":0.0005918784,"teacher_disagreement_score":0.0005446886,"about_ca_system_score_codex":0.00013176024,"about_ca_system_score_gemma":0.00016886902,"threshold_uncertainty_score":0.0018221736},"labels":[],"label_agreement":null},{"id":"W2101121629","doi":"10.1172/jci34538","title":"Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":393,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; Lastentautien Tutkimussäätiö; National Institutes of Health; Helsingin Sanomain Säätiö; National Center for Research Resources","keywords":"Kallmann syndrome; Hypogonadotropic hypogonadism; Endocrinology; Internal medicine; Biology; Gonadotropin-releasing hormone; Anosmia; Missense mutation; Kisspeptin; Proband; Mutation; Hypothalamus; Genetics; Luteinizing hormone; Medicine; Hormone; Gene","score_opus":0.08018849530208097,"score_gpt":0.36314998763855927,"score_spread":0.28296149233647827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101121629","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867504,0.0030758935,0.0055495575,0.00031368784,0.000041406976,0.00009443117,0.0010600024,0.0002646565,0.0028500615],"genre_scores_gemma":[0.9892252,0.0015787748,0.0063989,0.00015376441,0.000017171818,0.000107447995,0.00073896506,0.00005270214,0.0017269748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997558,0.000046172074,0.00003244385,0.00007981609,0.00005651728,0.000029311974],"domain_scores_gemma":[0.9999181,0.000018920002,0.000030410185,0.0000090540625,0.0000047194303,0.000018733208],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022329688,0.0006296769,0.0002786461,0.00083279854,0.0002325174,0.0002919373,0.00024882721,0.0006000252,0.0019357742],"category_scores_gemma":[0.00020359326,0.0002952683,0.0002733227,0.00019711003,0.00048271695,0.0001482795,0.0002644924,0.00036930136,0.000395667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005220969,0.00007868994,0.0024705247,0.00007971484,0.000047807673,0.0022483661,0.000063182975,0.00015053048,0.98521394,0.00062319194,0.000281756,0.008220269],"study_design_scores_gemma":[0.00070273946,0.0015241024,0.0815238,0.00012052406,0.00033925433,0.06955214,0.00023167103,0.0039459514,0.80580443,0.0010347294,0.035156887,0.00006375403],"about_ca_topic_score_codex":0.0008147505,"about_ca_topic_score_gemma":0.00083123706,"teacher_disagreement_score":0.0019357742,"about_ca_system_score_codex":0.00026687476,"about_ca_system_score_gemma":0.00023008842,"threshold_uncertainty_score":0.0064758062},"labels":[],"label_agreement":null},{"id":"W2101186431","doi":"10.1172/jci23858","title":"Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor–BI mediate HDL-initiated signaling","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Pfizer; American Heart Association","keywords":"Scavenger receptor; Cholesterol; Enos; PDZ domain; Cell biology; Chemistry; Biochemistry; Receptor; ABCA1; Biology; Biophysics; Lipoprotein; Transporter; Nitric oxide synthase","score_opus":0.08428455165070087,"score_gpt":0.3804750888605374,"score_spread":0.2961905372098365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101186431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98268247,0.002519055,0.010587296,0.00026385815,0.00003636219,0.000054586537,0.00019714137,0.00015313801,0.003506113],"genre_scores_gemma":[0.9912418,0.00087338313,0.0033168525,0.00007730325,0.000017273987,0.000040127237,0.000381999,0.000010561885,0.004040821],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998306,0.00001940579,0.000011186442,0.000033212964,0.000055799548,0.00004978392],"domain_scores_gemma":[0.9999324,0.0000072156713,0.000016231468,0.000008680435,0.00001299102,0.000022538537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001502291,0.00037767013,0.00022469321,0.00017828778,0.00027289902,0.00046917124,0.00024638762,0.00029629166,0.0009395342],"category_scores_gemma":[0.00013699716,0.00017442738,0.00029344976,0.00015715114,0.00019703616,0.0003647246,0.00048047514,0.0007292548,0.00064944255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088265,0.000020019212,0.00023240894,0.000020019443,0.000003861961,0.00006903195,0.00001723616,0.0000445295,0.9970186,0.00066128245,0.0000349097,0.0017899626],"study_design_scores_gemma":[0.000046493813,0.00010909154,0.007653259,0.000004773614,0.000013580915,0.00030714113,0.000037408707,0.0031490522,0.9851335,0.00033543984,0.0032023985,0.000007717249],"about_ca_topic_score_codex":0.0006985725,"about_ca_topic_score_gemma":0.00050542114,"teacher_disagreement_score":0.0009395342,"about_ca_system_score_codex":0.00048789778,"about_ca_system_score_gemma":0.00024391258,"threshold_uncertainty_score":0.0035399199},"labels":[],"label_agreement":null},{"id":"W2101378591","doi":"10.1172/jci15707","title":"The crucial role of Campylobacter jejuni genes in anti-ganglioside antibody induction in Guillain-Barré syndrome","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Peripheral Neuropathies and Disorders","field":"Medicine","cited_by":201,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Campylobacter jejuni; Guillain-Barre syndrome; Gene; Antibody; Ganglioside; Microbiology; Campylobacter; Virology; Antibody response; Biology; Medicine; Immunology; Genetics; Bacteria","score_opus":0.03563511978455202,"score_gpt":0.35141922635300876,"score_spread":0.31578410656845673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101378591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99872345,0.00030184526,0.0003984749,0.00006976795,0.0000065723843,0.000008530431,0.0000920777,0.000019198065,0.00038015904],"genre_scores_gemma":[0.99848795,0.00019922589,0.00067872234,0.00003230369,0.0000032963815,0.000011333663,0.000119190794,0.00000907424,0.00045879302],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999263,0.00001525781,0.000008683811,0.00001642281,0.000013279939,0.000020028107],"domain_scores_gemma":[0.99988484,0.00003454751,0.000028141194,0.000008683366,0.000008688959,0.000035108325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006953417,0.00034474424,0.00012772788,0.0002649404,0.00013532102,0.00013764006,0.00011805443,0.0003456255,0.0010903048],"category_scores_gemma":[0.0002214185,0.00012996476,0.0001177345,0.00009109128,0.00046747798,0.00010954932,0.000188425,0.0003027808,0.00017229239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003004809,0.00002861531,0.0022367593,0.000036758523,0.000003185482,0.0010556079,0.000030447798,0.00007933264,0.99462366,0.00007936881,0.0000329732,0.0014927756],"study_design_scores_gemma":[0.00009317608,0.00083631586,0.096517645,0.000030563664,0.00005331978,0.011083284,0.00016750196,0.0014936343,0.88663876,0.0003370184,0.0027317242,0.000017063623],"about_ca_topic_score_codex":0.00078201224,"about_ca_topic_score_gemma":0.0008617271,"teacher_disagreement_score":0.0010903048,"about_ca_system_score_codex":0.00030991243,"about_ca_system_score_gemma":0.00019298265,"threshold_uncertainty_score":0.0036475062},"labels":[],"label_agreement":null},{"id":"W2101998219","doi":"10.1172/jci14036","title":"Targeted expression of a human pituitary tumor–derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Mount Sinai Hospital; Ontario Institute for Cancer Research; University of Toronto","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Gene isoform; Fibroblast growth factor receptor 4; Biology; Pituitary tumors; Carcinogenesis; Pituitary gland; Cancer research; Receptor; Fibroblast growth factor receptor; In vivo; Cell biology; Fibroblast growth factor; Endocrinology; Cancer; Gene; Genetics; Hormone","score_opus":0.06421812979329598,"score_gpt":0.34586182030217427,"score_spread":0.2816436905088783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101998219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99640864,0.00040105602,0.0020782289,0.000053913715,0.000021591097,0.000030851224,0.00027573813,0.00006106731,0.00066885905],"genre_scores_gemma":[0.995138,0.00051585457,0.0022231413,0.000022918288,0.000008273946,0.000027102538,0.0005957972,0.00002147216,0.0014474553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998598,0.000022436752,0.000017353723,0.000028272781,0.000042435106,0.000029645591],"domain_scores_gemma":[0.99986863,0.000030499907,0.0000406891,0.000022674123,0.000007132593,0.000030405463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015344808,0.00035601904,0.00025990207,0.0002633026,0.0001551536,0.0002584577,0.00021019812,0.00022653544,0.00086588203],"category_scores_gemma":[0.00015499508,0.00019578407,0.00025891696,0.00013737114,0.00034179076,0.000135558,0.00019640499,0.00046116384,0.0003269759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081528975,0.000017068634,0.00013686465,0.000010694632,0.0000038645685,0.00014736249,0.0000072999937,0.000079546684,0.9989427,0.00006823678,0.000019107925,0.00048572986],"study_design_scores_gemma":[0.00004690001,0.00056165195,0.003426903,0.0000034641032,0.000033364366,0.0027168675,0.000030043557,0.00131578,0.9887678,0.00007655826,0.00301402,0.0000066334965],"about_ca_topic_score_codex":0.0010910793,"about_ca_topic_score_gemma":0.0013779721,"teacher_disagreement_score":0.0010910793,"about_ca_system_score_codex":0.0004052105,"about_ca_system_score_gemma":0.00030595157,"threshold_uncertainty_score":0.002939999},"labels":[],"label_agreement":null},{"id":"W2102277066","doi":"10.1172/jci8316","title":"Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":639,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Trophoblast; Oxygen tension; Placentation; Biology; Cell biology; Andrology; Endocrinology; Gelatinase; Internal medicine; Hypoxia (environmental); Placenta; Fetus; Matrix metalloproteinase; Chemistry; Pregnancy; Medicine; Biochemistry; Oxygen","score_opus":0.15376582541686828,"score_gpt":0.38831562163423977,"score_spread":0.2345497962173715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102277066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97425747,0.01624583,0.0025580141,0.0003519219,0.000078913334,0.000054570257,0.00042063795,0.00007543641,0.0059572933],"genre_scores_gemma":[0.98890823,0.005717396,0.001030168,0.00016189633,0.00002913877,0.000042387277,0.00052163925,0.000011851554,0.0035772626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999453,0.000012482976,0.000002705375,0.00000750945,0.000012602784,0.00001932988],"domain_scores_gemma":[0.9999627,0.0000065234726,0.000012344845,0.000002739245,0.0000053774197,0.00001023404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013040022,0.00019466552,0.00013642397,0.00013338872,0.00011701315,0.00019950302,0.00008970962,0.0001128826,0.0012702256],"category_scores_gemma":[0.000098631994,0.00008924757,0.0001815086,0.000070334645,0.00009496876,0.000079006466,0.0001266102,0.00026733062,0.00027250123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024321351,0.000028441167,0.00048906787,0.000050693743,0.0000049731084,0.00010303985,0.000052825675,0.000034524663,0.9959527,0.000098251294,0.00011671792,0.002825502],"study_design_scores_gemma":[0.00007850205,0.00060458336,0.03369237,0.000036308797,0.000047602098,0.00064782053,0.00014155092,0.00093308033,0.948255,0.00018943088,0.015367635,0.000006137683],"about_ca_topic_score_codex":0.0013858739,"about_ca_topic_score_gemma":0.0015375621,"teacher_disagreement_score":0.0013858739,"about_ca_system_score_codex":0.0002034551,"about_ca_system_score_gemma":0.00017458295,"threshold_uncertainty_score":0.0042493343},"labels":[],"label_agreement":null},{"id":"W2104284972","doi":"10.1172/jci64124","title":"Advances in stem cell therapy for spinal cord injury","year":2012,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":241,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital","funders":"Krembil Foundation; Ontario Neurotrauma Foundation; Christopher and Dana Reeve Foundation","keywords":"Stem cell; Spinal cord injury; Stem-cell therapy; Embryonic stem cell; Medicine; Transplantation; Reprogramming; Cell therapy; Neuroscience; Spinal cord; Cell; Psychology; Biology; Surgery; Psychiatry","score_opus":0.209234716721886,"score_gpt":0.4937144618491716,"score_spread":0.2844797451272856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104284972","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000051733583,0.99821305,0.00014291432,0.00043364606,0.00034580636,0.0000032219816,0.000007929661,0.00000539228,0.000796222],"genre_scores_gemma":[0.00034395797,0.99847656,0.00022551324,0.00024911956,0.00025085756,0.0000044818435,0.000011109205,0.0000014790154,0.00043688],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99975044,0.000050343428,0.000035849254,0.000038642258,0.000106122156,0.000018603387],"domain_scores_gemma":[0.99955195,0.00025095465,0.00003300607,0.000016038342,0.00011803122,0.000029928813],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010491487,0.00093240454,0.0011174966,0.002431283,0.00039154428,0.0010455103,0.00095284655,0.0015525136,0.0037965544],"category_scores_gemma":[0.0010387393,0.00025239866,0.0005061048,0.0024074637,0.000752513,0.0018308477,0.00085782626,0.0027994316,0.0025141311],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058599962,0.000082526414,0.000095378826,0.0123861255,0.000056854806,0.0002289248,0.00007684088,0.00034891986,0.0024683324,0.010177444,0.04323637,0.9307837],"study_design_scores_gemma":[0.000016222712,0.00006650334,0.00033474492,0.002391436,0.00005013577,0.00077358144,0.000042533124,0.000065036,0.0005445878,0.003539867,0.9921595,0.000015981472],"about_ca_topic_score_codex":0.0009342164,"about_ca_topic_score_gemma":0.0016092353,"teacher_disagreement_score":0.0037965544,"about_ca_system_score_codex":0.0007542321,"about_ca_system_score_gemma":0.0010950649,"threshold_uncertainty_score":0.0127007365},"labels":[],"label_agreement":null},{"id":"W2105330325","doi":"10.1172/jci16100","title":"The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Francisco; National Heart, Lung, and Blood Institute; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Heart and Stroke Foundation of Canada; American Heart Association; National Institutes of Health; National Science Foundation","keywords":"Internal medicine; Endocrinology; Muscle hypertrophy; Myocyte; Heart rate; Pressure overload; Cardiac function curve; Receptor; Knockout mouse; Stimulation; Biology; Cardiac myocyte; Genetically modified mouse; Blood pressure; Medicine; Heart failure; Cardiac hypertrophy; Transgene","score_opus":0.08104296557997151,"score_gpt":0.3382082378545646,"score_spread":0.25716527227459307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105330325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97789043,0.0026144767,0.011235088,0.00052272284,0.00023419518,0.00015636465,0.0034452558,0.00059401145,0.003307425],"genre_scores_gemma":[0.9503937,0.003769478,0.019787114,0.00052803993,0.0001956358,0.0006065566,0.00459865,0.0007892452,0.01933152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991314,0.00009367601,0.00015621104,0.00030374105,0.00020236874,0.00011263914],"domain_scores_gemma":[0.9989015,0.000116616895,0.0004208372,0.000103701925,0.000080894875,0.0003765276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005147672,0.0013630845,0.0007247999,0.0014944751,0.0005297124,0.00065683183,0.00064016477,0.0011986803,0.005758177],"category_scores_gemma":[0.0003422569,0.0010053895,0.0008042081,0.00040322336,0.0007870626,0.0005483146,0.00056889164,0.0020601705,0.0017864864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018965597,0.00004595035,0.00023595797,0.000033652672,0.000009183446,0.00015336311,0.000021839645,0.000024777151,0.9983005,0.00013972036,0.00007592749,0.0007695086],"study_design_scores_gemma":[0.0004952243,0.0010594705,0.036841176,0.00012446044,0.00021597362,0.006234302,0.0002067376,0.002211635,0.93927974,0.0003739602,0.0129026305,0.00005461856],"about_ca_topic_score_codex":0.0006511118,"about_ca_topic_score_gemma":0.0010016579,"teacher_disagreement_score":0.005758177,"about_ca_system_score_codex":0.00037969954,"about_ca_system_score_gemma":0.0003304185,"threshold_uncertainty_score":0.01926297},"labels":[],"label_agreement":null},{"id":"W2106431826","doi":"10.1172/jci64560","title":"HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Maple Leaf Medical Clinic; Simon Fraser University; St. Michael's Hospital","funders":"National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network; Ontario Innovation Trust; National Institutes of Health; Pfizer","keywords":"Biology; Virology; Cytotoxic T cell; CD8; Simian immunodeficiency virus; Immune system; T cell; Long terminal repeat; Antigen; Virus; Genome; In vitro; Immunology; Genetics; Gene","score_opus":0.07784058759385254,"score_gpt":0.2911674121585729,"score_spread":0.21332682456472035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106431826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99521446,0.00059185567,0.002334157,0.000052905707,0.000025637579,0.00006681348,0.00007179808,0.000059777896,0.001582492],"genre_scores_gemma":[0.9951793,0.00034562778,0.00168,0.00012379748,0.000040191004,0.000044102304,0.00019023355,0.000015490285,0.0023812267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997806,0.000026971516,0.000012204677,0.000053007065,0.000031041123,0.00009633123],"domain_scores_gemma":[0.9999075,0.000022499835,0.000013225129,0.000020014095,0.000013280625,0.00002346799],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014464416,0.00040488289,0.0003638923,0.00012665597,0.00013669442,0.00031980211,0.0002908968,0.00033261825,0.0019027502],"category_scores_gemma":[0.00013764111,0.00010542485,0.00031384616,0.0000548231,0.00016489098,0.00019918541,0.00024257445,0.000911603,0.00045063614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020194601,0.00015172386,0.0006954223,0.0000530405,0.000011711978,0.00010256892,0.000051915093,0.000365215,0.98969567,0.00015844607,0.000096470896,0.008415926],"study_design_scores_gemma":[0.00022520489,0.003658317,0.0077928514,0.00004505885,0.00007134477,0.001662069,0.00016238158,0.0037470844,0.97380334,0.0005517344,0.008267536,0.000012996739],"about_ca_topic_score_codex":0.00019351719,"about_ca_topic_score_gemma":0.00044211524,"teacher_disagreement_score":0.0019027502,"about_ca_system_score_codex":0.00015621053,"about_ca_system_score_gemma":0.00018044526,"threshold_uncertainty_score":0.006365359},"labels":[],"label_agreement":null},{"id":"W2106758941","doi":"10.1172/jci73451","title":"DEAD-box helicase DP103 defines metastatic potential of human breast cancers","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"National Medical Research Council; National Institute of General Medical Sciences; Medical Research Council; Ministry of Education, India; Cancer Science Institute of Singapore, National University of Singapore; National Cancer Institute; National Institutes of Health","keywords":"Breast cancer; Metastasis; MMP9; Cancer research; Oncogene; Medicine; Cancer; PAK1; Metastatic breast cancer; NF-κB; Oncology; Signal transduction; Internal medicine; Downregulation and upregulation; Biology; Cell cycle; Inflammation","score_opus":0.054458797135362655,"score_gpt":0.3557076958244294,"score_spread":0.30124889868906674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106758941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98348373,0.0072455937,0.0035922546,0.00015036517,0.000021735805,0.00004687257,0.0011039653,0.00008386403,0.004271699],"genre_scores_gemma":[0.9944865,0.0016787553,0.001022519,0.000040951574,0.0000073367746,0.00001913707,0.0008052006,0.000008112872,0.0019315087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999069,0.000013361312,0.000007947412,0.000022286818,0.000029837709,0.000019664783],"domain_scores_gemma":[0.99994564,0.0000071418212,0.000017309296,0.000004081133,0.000009609391,0.000016204927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007764872,0.0001681476,0.00012754409,0.00041559676,0.00010224124,0.00029941188,0.00006915486,0.00018772224,0.0015970666],"category_scores_gemma":[0.00012457637,0.0000852793,0.00006484277,0.00021239812,0.00012141644,0.0001113334,0.00011636921,0.0002001533,0.00033797766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016026307,0.000021288652,0.0031711939,0.000041254527,0.00000559285,0.00012811278,0.000019183932,0.000050590523,0.98974496,0.00013105449,0.00018023569,0.006346393],"study_design_scores_gemma":[0.000043703756,0.0005719045,0.1287356,0.000025070642,0.00004528568,0.0064917235,0.00017677671,0.0021152147,0.8373213,0.00046955462,0.023986407,0.000017400043],"about_ca_topic_score_codex":0.00049614755,"about_ca_topic_score_gemma":0.00065442215,"teacher_disagreement_score":0.0015970666,"about_ca_system_score_codex":0.00018616453,"about_ca_system_score_gemma":0.00010385857,"threshold_uncertainty_score":0.0053427815},"labels":[],"label_agreement":null},{"id":"W2106984011","doi":"10.1172/jci25483","title":"Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":286,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Incretin; Internal medicine; Endocrinology; Glucose homeostasis; Resistin; Energy homeostasis; Receptor; Gastric inhibitory polypeptide; Insulin resistance; Insulin; Biology; Chemistry; Type 2 diabetes; Glucagon; Diabetes mellitus; Medicine; Adipokine","score_opus":0.03663757570630926,"score_gpt":0.3570815698143817,"score_spread":0.32044399410807245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106984011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99712163,0.0014190143,0.00058074424,0.00003705835,0.000005455722,0.0000042316938,0.00004076994,0.000023266326,0.00076771714],"genre_scores_gemma":[0.99599,0.0018434286,0.0009823282,0.00003695129,0.00001696026,0.000011117762,0.00007501838,0.000011307735,0.0010329346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995553,0.000009832266,0.000002766735,0.000009702973,0.000009604126,0.000012557514],"domain_scores_gemma":[0.9999367,0.000009240032,0.000023042468,0.0000076314545,0.0000050734448,0.000018334373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000087992245,0.00026002325,0.00016041819,0.00016306835,0.0000537079,0.00021905072,0.00009788934,0.000112725116,0.0007346075],"category_scores_gemma":[0.0001509475,0.000112893795,0.00006306931,0.00008301057,0.00016098561,0.00020061855,0.00012701214,0.0002829309,0.000119440156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009923447,0.00008049349,0.0034549732,0.00004154691,0.000016650103,0.00011949255,0.000020673304,0.0000764099,0.9819962,0.00011149737,0.000056112698,0.013033636],"study_design_scores_gemma":[0.00028502915,0.002600332,0.49291688,0.000030087926,0.00017795108,0.002199146,0.00017354164,0.0020043743,0.49431035,0.00071705814,0.004564352,0.000020962816],"about_ca_topic_score_codex":0.00011916246,"about_ca_topic_score_gemma":0.0002158644,"teacher_disagreement_score":0.0007346075,"about_ca_system_score_codex":0.00010550198,"about_ca_system_score_gemma":0.00004779523,"threshold_uncertainty_score":0.0024574995},"labels":[],"label_agreement":null},{"id":"W2107749499","doi":"10.1172/jci43030","title":"Caveat mTOR: aberrant signaling disrupts corticogenesis","year":2010,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; King's College London","keywords":"Corticogenesis; PI3K/AKT/mTOR pathway; Megalencephaly; Mechanistic target of rapamycin; Epilepsy; Cancer research; Signal transducing adaptor protein; Forebrain; Phenotype; Signal transduction; Neuroscience; Medicine; Biology; Cell biology; Stem cell; Genetics; Central nervous system; Progenitor cell","score_opus":0.2119311959351175,"score_gpt":0.4246206764255147,"score_spread":0.2126894804903972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107749499","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14243275,0.02478961,0.0031195858,0.7446657,0.023928622,0.00023634544,0.00041610067,0.0012734345,0.05913792],"genre_scores_gemma":[0.60495853,0.018014554,0.0035461562,0.28146276,0.043597903,0.00019547301,0.00023159837,0.00020513353,0.047787845],"study_design_codex":"case_report","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997594,0.000055178258,0.000025438158,0.00003347018,0.000066532804,0.000060081875],"domain_scores_gemma":[0.99951065,0.0003030686,0.000055594643,0.000029239769,0.000041436044,0.000059968766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033070587,0.00055956584,0.0006168125,0.00033002088,0.0007373425,0.0007781769,0.00049200834,0.0074002394,0.002011077],"category_scores_gemma":[0.0019908964,0.00024353428,0.0004268761,0.0002787024,0.0008928929,0.00053793844,0.00030602273,0.004051093,0.0012814904],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089930295,0.00025300062,0.0062906006,0.0004666708,0.00016253543,0.5004304,0.0003078079,0.0008258215,0.025127836,0.013092392,0.37587637,0.07626726],"study_design_scores_gemma":[0.0010529755,0.00050831016,0.011864197,0.0002125911,0.00018011291,0.5785816,0.00028769634,0.005859674,0.016316552,0.013453209,0.37158126,0.000101795435],"about_ca_topic_score_codex":0.0013560853,"about_ca_topic_score_gemma":0.0027274496,"teacher_disagreement_score":0.0074002394,"about_ca_system_score_codex":0.0015049579,"about_ca_system_score_gemma":0.00048012717,"threshold_uncertainty_score":0.010919273},"labels":[],"label_agreement":null},{"id":"W2107808656","doi":"10.1172/jci42869","title":"BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Weill Cornell Medical College; National Cancer Institute; National Institutes of Health; College of Veterinary Medicine, Cornell University; Memorial Sloan-Kettering Cancer Center; Geoffrey Beene Cancer Research Center; Commonwealth Foundation; Leukemia and Lymphoma Society; Michael Smith Health Research BC; Canadian Institutes of Health Research; Chemotherapy Foundation","keywords":"Biology; Cancer research; BCL6; P300-CBP Transcription Factors; Histone acetyltransferase; Histone deacetylase inhibitor; Histone deacetylase; Molecular biology; Acetylation; B cell; Immunology; Histone; Genetics; Gene; Antibody; Germinal center","score_opus":0.04215585285881388,"score_gpt":0.3809938247419264,"score_spread":0.3388379718831125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107808656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92891544,0.0109101925,0.04432499,0.0005201634,0.00015442482,0.00055954896,0.0011117173,0.00060321315,0.012900236],"genre_scores_gemma":[0.9853078,0.0031446272,0.0077940384,0.00009171858,0.000019733121,0.0001421336,0.00069746614,0.0000342895,0.0027682367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998989,0.000013139578,0.000007053247,0.000019346026,0.000032578755,0.000029007886],"domain_scores_gemma":[0.9999682,0.0000032621351,0.0000065462555,0.000005201287,0.0000054011016,0.000011486527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013312798,0.000448983,0.00036004715,0.0002995318,0.00013138037,0.00034460326,0.00044624068,0.00021768032,0.001214564],"category_scores_gemma":[0.000076832686,0.00014396304,0.00025167008,0.00024928837,0.00016955879,0.00020529484,0.00032500207,0.0009071014,0.0005416581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028534836,0.00026188235,0.00034067218,0.00011057518,0.000024282637,0.00012634695,0.000028414011,0.0013342742,0.9724161,0.0014958375,0.00040603476,0.023170112],"study_design_scores_gemma":[0.0002971944,0.0016297441,0.001639735,0.000015607004,0.000090357644,0.00066231034,0.000027316173,0.0059532006,0.9683992,0.0005056528,0.020763861,0.000015819463],"about_ca_topic_score_codex":0.00039550805,"about_ca_topic_score_gemma":0.0011425464,"teacher_disagreement_score":0.001214564,"about_ca_system_score_codex":0.0004028009,"about_ca_system_score_gemma":0.0001948512,"threshold_uncertainty_score":0.0040631294},"labels":[],"label_agreement":null},{"id":"W2107984202","doi":"10.1172/jci12067","title":"Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":247,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Amgen (Canada); Montreal Children's Hospital; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Amgen","keywords":"Matrix metalloproteinase; Air space; Tissue inhibitor of metalloproteinase; Chemistry; Pathology; Cell biology; Biology; Medicine; Biochemistry","score_opus":0.05975413769542971,"score_gpt":0.37796868422249724,"score_spread":0.31821454652706754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107984202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99121934,0.0017411251,0.004732307,0.0002093352,0.00006526489,0.00006364454,0.0008432155,0.00025418127,0.0008716496],"genre_scores_gemma":[0.9879441,0.0012799212,0.0037647204,0.00014168065,0.000049842176,0.00014726695,0.0015474933,0.00010072151,0.005024335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999684,0.00004719182,0.000041253003,0.00008352527,0.00007852941,0.000065608016],"domain_scores_gemma":[0.99912125,0.00013052812,0.00029823664,0.00008339049,0.00005045339,0.000316062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046318976,0.00073666015,0.00052208494,0.00076268846,0.0002927149,0.0004172328,0.00026424666,0.0007229845,0.0019770872],"category_scores_gemma":[0.00033832033,0.00038404358,0.0004911309,0.00019765882,0.00066854845,0.00053926115,0.00036001453,0.0014111834,0.0005208865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038380167,0.00013492719,0.0009316483,0.000036707268,0.0000102309195,0.00057246635,0.00004268607,0.00003617607,0.9960587,0.00015882458,0.00007483134,0.0015590102],"study_design_scores_gemma":[0.00027196694,0.005142084,0.04861548,0.000041383857,0.00009410819,0.011869906,0.00015794688,0.001174686,0.9282573,0.00041761075,0.003920605,0.000037019843],"about_ca_topic_score_codex":0.00024360119,"about_ca_topic_score_gemma":0.0004262448,"teacher_disagreement_score":0.0019770872,"about_ca_system_score_codex":0.0002743508,"about_ca_system_score_gemma":0.00022514077,"threshold_uncertainty_score":0.0066140294},"labels":[],"label_agreement":null},{"id":"W2108141823","doi":"10.1172/jci21838","title":"High-level β-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Heart, Lung, and Blood Institute; Genentech; National Institutes of Health; Stem Cell Network","keywords":"Biology; Haematopoiesis; Cord blood; Transgene; Stem cell; Viral vector; Transduction (biophysics); Molecular biology; Genetic enhancement; Progenitor cell; Globin; Transplantation; CD34; Myeloid; Gene; Virology; Cancer research; Immunology; Cell biology; Genetics; Recombinant DNA; Medicine","score_opus":0.08391455691124541,"score_gpt":0.36417505667063726,"score_spread":0.2802604997593918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108141823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832191,0.0010814222,0.013345188,0.000079633515,0.000016896232,0.00009725595,0.00019887667,0.00017338526,0.0017882956],"genre_scores_gemma":[0.9923516,0.0004958361,0.0049856016,0.0000435487,0.000007365107,0.00003550398,0.0003818458,0.00004885137,0.0016498476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997249,0.00005515899,0.000029250445,0.000053748518,0.00009769648,0.000039252027],"domain_scores_gemma":[0.99982786,0.000033403525,0.000048408943,0.000034980967,0.00003086912,0.000024506362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003619905,0.00022728032,0.00018133888,0.00023440455,0.000114304814,0.0005018933,0.0001673046,0.00024054077,0.00075353304],"category_scores_gemma":[0.00020460969,0.0001176741,0.00013259538,0.00015373116,0.00026800178,0.00013471078,0.00018223414,0.00047904695,0.0003906519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002382983,0.000010430387,0.0003131869,0.000009976684,0.0000020973482,0.000028541092,0.000017780207,0.000028068927,0.9979146,0.000069228874,0.000012228119,0.0015699876],"study_design_scores_gemma":[0.0000064295987,0.00013277656,0.0027491213,0.000004735737,0.000012157259,0.00042740107,0.000014734097,0.0005421819,0.99468416,0.000033547556,0.0013906537,0.0000020175657],"about_ca_topic_score_codex":0.00057793333,"about_ca_topic_score_gemma":0.0005590357,"teacher_disagreement_score":0.00075353304,"about_ca_system_score_codex":0.00024890766,"about_ca_system_score_gemma":0.00026635313,"threshold_uncertainty_score":0.0025207996},"labels":[],"label_agreement":null},{"id":"W2108409620","doi":"10.1172/jci13359","title":"Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Universidad Nacional de La Plata; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; Johns Hopkins University; American Heart Association","keywords":"Contractility; Repolarization; Heart failure; Medicine; Calcium; Heartbeat; Internal medicine; Cardiology; Potassium channel; Endocrinology; Electrophysiology; Computer science","score_opus":0.08638200485610341,"score_gpt":0.3674533772217543,"score_spread":0.2810713723656509,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108409620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97487766,0.0024580737,0.018508535,0.0004143077,0.00022486734,0.00017864924,0.00016152901,0.00023696426,0.0029394454],"genre_scores_gemma":[0.9801328,0.0021186832,0.013571377,0.00012596007,0.00006593818,0.00014232504,0.00013421813,0.000045188743,0.0036635203],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996942,0.00004744565,0.00003248197,0.00007289226,0.00008221549,0.00007068963],"domain_scores_gemma":[0.9998349,0.000038776954,0.000056074623,0.000019751289,0.000011721149,0.00003884005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003445678,0.00057982386,0.0006563613,0.00041288353,0.00019954563,0.00042456295,0.0003126075,0.00059348496,0.0012219726],"category_scores_gemma":[0.00020767012,0.0002072413,0.00034831988,0.00015370185,0.00047114067,0.0003654064,0.0003974233,0.0009665908,0.00023230445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013414596,0.000065904234,0.00007063651,0.000043933935,0.0000080329755,0.000058083842,0.0000146561915,0.00011739314,0.99519086,0.00032472043,0.000050331942,0.003921217],"study_design_scores_gemma":[0.00009756816,0.0016951306,0.0008569144,0.0000113220285,0.00006971194,0.0007090181,0.000022687409,0.0015271999,0.990424,0.0001355401,0.004439237,0.000011747039],"about_ca_topic_score_codex":0.00012800464,"about_ca_topic_score_gemma":0.00040101822,"teacher_disagreement_score":0.0012219726,"about_ca_system_score_codex":0.00021767389,"about_ca_system_score_gemma":0.00020205909,"threshold_uncertainty_score":0.004087925},"labels":[],"label_agreement":null},{"id":"W2108595427","doi":"10.1172/jci32727","title":"Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":198,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"University of California, San Diego; Medical Research Council; Korea Science and Engineering Foundation; Dong-A University; Imperial College London; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services; Cancer Research UK; University of Pittsburgh","keywords":"Oncolytic virus; Vaccinia; Systemic administration; In vivo; Cancer; Cancer cell; Cancer research; Ex vivo; Virology; Biology; Medicine; Immunology; Virus; Gene; Internal medicine","score_opus":0.027545429648608146,"score_gpt":0.3584723242434685,"score_spread":0.33092689459486035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108595427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9530987,0.00088827155,0.042273775,0.00014499224,0.000052064865,0.00029467145,0.00040403346,0.00016768511,0.0026756874],"genre_scores_gemma":[0.93908095,0.0014129811,0.05469159,0.00005561896,0.000012828681,0.00014406689,0.00063975615,0.000089607805,0.0038726358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979275,0.000035645844,0.00002443759,0.000037444053,0.00008040863,0.000029333834],"domain_scores_gemma":[0.99987507,0.000025176952,0.00004969041,0.000017606275,0.000015028827,0.0000173785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032526307,0.0004185235,0.0002842265,0.00022435901,0.00017492287,0.00048854423,0.0002874128,0.00030371695,0.00049589504],"category_scores_gemma":[0.00021607032,0.00018332707,0.00026429453,0.0001635935,0.0003128117,0.00023927746,0.00026205412,0.00068314065,0.00026646975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043467317,0.00005506051,0.00017669928,0.00002522571,0.0000037049222,0.000059913997,0.000017020438,0.0004812116,0.99568224,0.00059660955,0.000040572293,0.0028183225],"study_design_scores_gemma":[0.00003084987,0.00044249752,0.0007081088,0.0000083665445,0.000012307539,0.00038094594,0.000020147041,0.001735911,0.992187,0.00009890192,0.004368619,0.0000063153866],"about_ca_topic_score_codex":0.00035117636,"about_ca_topic_score_gemma":0.00057013176,"teacher_disagreement_score":0.00049589504,"about_ca_system_score_codex":0.0002557844,"about_ca_system_score_gemma":0.00037812119,"threshold_uncertainty_score":0.0018557906},"labels":[],"label_agreement":null},{"id":"W2108729511","doi":"10.1172/jci36411","title":"Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":159,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Canadian Association of Gastroenterology","keywords":"Immune system; TLR4; Biology; Bone marrow; Innate immune system; Immunology; Lipopolysaccharide; Endothelium; Microbiology; Systemic administration; Inflammation; In vivo","score_opus":0.055540186694940284,"score_gpt":0.3141718304890996,"score_spread":0.2586316437941593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108729511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737442,0.0012717899,0.016581662,0.0006736732,0.00018988246,0.00023014398,0.0024159618,0.0009948427,0.0038977335],"genre_scores_gemma":[0.94529456,0.0014845233,0.022664793,0.00041938561,0.00008989627,0.0005001613,0.0027308664,0.00041971912,0.026396025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991636,0.00013243646,0.00009083373,0.0002062088,0.00018399839,0.00022287706],"domain_scores_gemma":[0.998966,0.000104336475,0.0004685286,0.00013137294,0.00007726428,0.00025251537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074466417,0.0011891717,0.0005927944,0.0010098029,0.00035057944,0.0008442847,0.00081289164,0.0014364409,0.004438438],"category_scores_gemma":[0.00044000123,0.0007567901,0.00060137094,0.00027537203,0.00084753067,0.0007341967,0.0004885261,0.0023181692,0.0014702806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006065319,0.00032148833,0.00034202516,0.00006229698,0.000022723843,0.00022077013,0.000027928527,0.00018279567,0.9954129,0.00045905044,0.00025701438,0.002084588],"study_design_scores_gemma":[0.00042411807,0.0020670684,0.005332206,0.000050912833,0.000096418225,0.0014751208,0.000075709926,0.0030548456,0.979341,0.00034177006,0.0077043534,0.000036410165],"about_ca_topic_score_codex":0.00058792136,"about_ca_topic_score_gemma":0.0009655328,"teacher_disagreement_score":0.004438438,"about_ca_system_score_codex":0.0006008064,"about_ca_system_score_gemma":0.00040218397,"threshold_uncertainty_score":0.014848053},"labels":[],"label_agreement":null},{"id":"W2108821770","doi":"10.1172/jci38902","title":"The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":286,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Ottawa Regional Cancer Foundation; University of Ottawa","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; University of California, San Francisco; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; University of Missouri","keywords":"T cell; Histone deacetylase; Experimental autoimmune encephalomyelitis; Autoimmunity; Sirtuin 1; Peripheral tolerance; Cell biology; Biology; Immunology; Transcription factor; Downregulation and upregulation; Immune tolerance; Cancer research; Histone; Immune system; Biochemistry","score_opus":0.04355535484365589,"score_gpt":0.39007605912794396,"score_spread":0.34652070428428805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108821770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9766747,0.0044255345,0.012419078,0.00059433613,0.00015106327,0.000074059884,0.001235924,0.000895428,0.0035300052],"genre_scores_gemma":[0.9858686,0.0020830645,0.005824662,0.00017013852,0.000048219616,0.00007376184,0.00095578836,0.00011628183,0.004859496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996481,0.000063769505,0.000032745746,0.00009103521,0.000094755036,0.00006956844],"domain_scores_gemma":[0.99963415,0.000023980783,0.00016138036,0.00004796209,0.000028420909,0.0001042097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028897182,0.0005381813,0.0004110983,0.0008106615,0.00027475812,0.00050691125,0.0004934105,0.00058613595,0.0020063948],"category_scores_gemma":[0.00020435039,0.00043172986,0.00043013904,0.00029017357,0.0005189981,0.0002756644,0.00030599823,0.0010926896,0.0008890477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002485932,0.00003429508,0.000321906,0.00004283832,0.000013245606,0.00007471891,0.000014524288,0.000062266714,0.996191,0.00020339993,0.000103725855,0.002689483],"study_design_scores_gemma":[0.0001298579,0.0008249978,0.011197323,0.000029966888,0.0001005891,0.0008670835,0.000046205787,0.0014734664,0.9726438,0.00041354995,0.012251475,0.000021615404],"about_ca_topic_score_codex":0.0005017328,"about_ca_topic_score_gemma":0.0007509027,"teacher_disagreement_score":0.0020063948,"about_ca_system_score_codex":0.00042212338,"about_ca_system_score_gemma":0.00030427545,"threshold_uncertainty_score":0.0067120194},"labels":[],"label_agreement":null},{"id":"W2109100155","doi":"10.1172/jci60132","title":"SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":351,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"National Heart, Lung, and Blood Institute; Medical Center, University of Rochester; National Institutes of Health; Helsingin ja Uudenmaan Sairaanhoitopiiri; National Institute of Environmental Health Sciences; University of Rochester","keywords":"Senescence; Sirtuin 1; Sirtuin; Inflammation; FOXO3; COPD; Medicine; Cancer research; Activator (genetics); Immunology; Biology; Internal medicine; NAD+ kinase; Cell biology; Signal transduction; Downregulation and upregulation; Biochemistry; Protein kinase B; Enzyme","score_opus":0.05654043227558687,"score_gpt":0.3677061157159902,"score_spread":0.31116568344040335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109100155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836326,0.00325883,0.006892679,0.00116241,0.00023684786,0.000112260874,0.0011363706,0.00086635427,0.0027016392],"genre_scores_gemma":[0.9814047,0.0028016414,0.0072461125,0.00042383678,0.00008817764,0.00020844565,0.0011371785,0.00013318277,0.0065566665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976116,0.000054015778,0.000027836724,0.000047209513,0.00004565712,0.00006410759],"domain_scores_gemma":[0.99974936,0.000014367234,0.000087705914,0.000037471076,0.000022438422,0.00008865213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005971296,0.00062757736,0.0006084731,0.00091697223,0.000309631,0.00035835974,0.0004565613,0.0006461273,0.0024502582],"category_scores_gemma":[0.00018892567,0.00038525788,0.000722418,0.0003172123,0.0007038594,0.0004011671,0.00032565588,0.0015068193,0.00070690527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019817792,0.00043990905,0.00029738963,0.00011560872,0.000031908796,0.00006696613,0.000050103303,0.00012199551,0.99089116,0.0004765666,0.0002782581,0.0052485135],"study_design_scores_gemma":[0.0012103302,0.006457551,0.009600655,0.00007568063,0.00016520085,0.0005175644,0.000101646336,0.0027747648,0.9662529,0.0008452521,0.011960617,0.000037799757],"about_ca_topic_score_codex":0.0005936663,"about_ca_topic_score_gemma":0.0010385385,"teacher_disagreement_score":0.0024502582,"about_ca_system_score_codex":0.0003582957,"about_ca_system_score_gemma":0.0005237515,"threshold_uncertainty_score":0.00819695},"labels":[],"label_agreement":null},{"id":"W2109114226","doi":"10.1172/jci23628","title":"Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRα phosphorylation","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Cancer Institute; Samuel Waxman Cancer Research Foundation","keywords":"Arsenic trioxide; Phosphorylation; Arsenic; Nuclear receptor; Cell biology; Retinoid X receptor; Chemistry; Cancer research; Receptor; Function (biology); Biology; Biochemistry; Transcription factor; Gene","score_opus":0.02352810111409606,"score_gpt":0.29550764753587094,"score_spread":0.2719795464217749,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109114226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98902357,0.0050752405,0.0026120667,0.0003102462,0.00008813972,0.0000407892,0.00025804903,0.00008691951,0.002505073],"genre_scores_gemma":[0.9928768,0.0029507244,0.0015661774,0.00006610397,0.000019599624,0.000039841634,0.00027132442,0.000008977102,0.0022002948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999087,0.000022961754,0.000011397244,0.000012474165,0.000022537379,0.000021926146],"domain_scores_gemma":[0.99996173,0.000005274844,0.000012950457,0.000004475238,0.0000061892597,0.0000092876535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011975503,0.00041856858,0.00023209058,0.00016178087,0.0001648124,0.00023938106,0.00013251333,0.00013424108,0.0013473879],"category_scores_gemma":[0.00008478525,0.00008138907,0.00022200047,0.00012360538,0.0002500184,0.00014599157,0.00012037143,0.00037410506,0.00024927148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037376475,0.00004240808,0.00012133659,0.00009796793,0.000010736266,0.000050154027,0.000017202574,0.00007864366,0.9973998,0.000109819266,0.000066612825,0.0016315792],"study_design_scores_gemma":[0.000074507705,0.00048140922,0.0027074388,0.000006018895,0.00002206034,0.00026171867,0.000048257607,0.00061984535,0.992894,0.0001063064,0.002773814,0.000004756282],"about_ca_topic_score_codex":0.0003370508,"about_ca_topic_score_gemma":0.00082762196,"teacher_disagreement_score":0.0013473879,"about_ca_system_score_codex":0.00021355865,"about_ca_system_score_gemma":0.00022026732,"threshold_uncertainty_score":0.004507482},"labels":[],"label_agreement":null},{"id":"W2109672256","doi":"10.1172/jci44999","title":"The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Immunology; Asthma; Zymosan; House dust mite; Immune system; Inflammation; Lipopolysaccharide; Aspergillus fumigatus; Medicine; Biology; Allergy; In vitro; Allergen","score_opus":0.06801175901987838,"score_gpt":0.3355508324542272,"score_spread":0.2675390734343488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109672256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9713329,0.006805916,0.010023062,0.0017615682,0.0004688785,0.00025435875,0.004175557,0.0006901434,0.0044876593],"genre_scores_gemma":[0.97327054,0.004016965,0.008694269,0.00057035394,0.00013078797,0.0006749679,0.002597195,0.00012313292,0.009921769],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991227,0.00017497892,0.00012724915,0.00017233384,0.0002241586,0.0001787126],"domain_scores_gemma":[0.9995433,0.000028623135,0.00013202,0.000065163316,0.000033163225,0.00019775749],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005051454,0.0011303982,0.0008361509,0.0012442542,0.00047954376,0.0006434663,0.00057312177,0.0012794056,0.0040145847],"category_scores_gemma":[0.00015668746,0.00053864624,0.0011400823,0.00041733807,0.0008233539,0.00063612574,0.0004416022,0.004368737,0.001108056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009934348,0.00033622808,0.00042765585,0.00015371169,0.000022507067,0.00016409937,0.000030618194,0.0001139039,0.9956892,0.00025380118,0.00017191941,0.0016428307],"study_design_scores_gemma":[0.00033649124,0.0035101431,0.01217043,0.000101642705,0.00012708356,0.0016107762,0.0001581404,0.0025525328,0.96986043,0.00047888557,0.0090619605,0.0000315106],"about_ca_topic_score_codex":0.0004560026,"about_ca_topic_score_gemma":0.00070848275,"teacher_disagreement_score":0.0040145847,"about_ca_system_score_codex":0.00041704474,"about_ca_system_score_gemma":0.0003818996,"threshold_uncertainty_score":0.013430119},"labels":[],"label_agreement":null},{"id":"W2109882045","doi":"10.1172/jci74985","title":"Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":620,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"National Heart, Lung, and Blood Institute; Weill Cornell Medical College; College of Veterinary Medicine, Cornell University; National Institutes of Health; Brigham and Women's Hospital","keywords":"Necroptosis; Mitophagy; PINK1; Mitochondrion; Autophagy; Programmed cell death; Cell biology; Pathogenesis; Parkin; Biology; Mitochondrial ROS; Immunology; Cancer research; Medicine; Pathology; Apoptosis; Biochemistry; Disease","score_opus":0.049808708557568145,"score_gpt":0.3692851976442535,"score_spread":0.31947648908668536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109882045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84721726,0.13943592,0.006870337,0.0015150746,0.00019875541,0.000104876075,0.00030132596,0.00030278615,0.004053669],"genre_scores_gemma":[0.9710094,0.025879767,0.0012114181,0.00019446286,0.000079634585,0.000027416849,0.00012197967,0.00001009463,0.0014659152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987304,0.000025000945,0.0000151247,0.00003022352,0.00003234437,0.000024279305],"domain_scores_gemma":[0.9998846,0.000011334751,0.000047253903,0.000009766443,0.000015548585,0.000031628522],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027717,0.00042853368,0.0003320831,0.0003312723,0.00029941075,0.00048788593,0.00019204064,0.00048471693,0.00063726417],"category_scores_gemma":[0.00017096405,0.00013894806,0.00027105614,0.00018046575,0.00039080833,0.00029216954,0.00052311935,0.00075359584,0.0001778594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010092802,0.00017108825,0.0081152255,0.0009138758,0.00010015586,0.0014220874,0.00011285726,0.0005867876,0.9588108,0.0012206591,0.0007017816,0.026835456],"study_design_scores_gemma":[0.00031930773,0.0025181884,0.25512242,0.0004401083,0.0004938642,0.016258197,0.0006154518,0.008207554,0.6589524,0.0059950305,0.050997667,0.00007982148],"about_ca_topic_score_codex":0.00033060662,"about_ca_topic_score_gemma":0.0004687805,"teacher_disagreement_score":0.00063726417,"about_ca_system_score_codex":0.00038785973,"about_ca_system_score_gemma":0.0002541775,"threshold_uncertainty_score":0.0028141737},"labels":[],"label_agreement":null},{"id":"W2109975654","doi":"10.1172/jci35381","title":"GSK-3β in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1–dependent mechanism","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Western University","funders":"Canadian Arthritis Network; Ontario Ministry of Research and Innovation; Schulich School of Medicine and Dentistry; Canadian Institutes of Health Research; Arthritis Society","keywords":"Wound healing; Fibrosis; Mechanism (biology); Endothelin 1; Fibroblast; Medicine; Endothelin receptor; Cell biology; Pathology; Chemistry; Biology; Internal medicine; Immunology; Biochemistry; In vitro; Receptor","score_opus":0.0614650940804485,"score_gpt":0.33584126419194255,"score_spread":0.27437617011149407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109975654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95656997,0.01276025,0.015210086,0.00089923694,0.00054913404,0.00029473612,0.0033557694,0.0015118218,0.00884893],"genre_scores_gemma":[0.9689636,0.005280547,0.009508776,0.00026274426,0.00007578366,0.0005818473,0.0023318361,0.00021557587,0.012779321],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995943,0.000053752257,0.00006595971,0.000110946115,0.00009412049,0.00008093106],"domain_scores_gemma":[0.9996903,0.000026056696,0.00011811231,0.00005419765,0.000023318878,0.000088030974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003853126,0.0008881471,0.00045204,0.0010406927,0.00033221953,0.00062831404,0.0003956536,0.00061965646,0.0035560422],"category_scores_gemma":[0.00020997817,0.0006087973,0.00067526277,0.0004446117,0.00056410744,0.00036567225,0.0003212818,0.0012587467,0.0015643463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055373466,0.00011976831,0.00018215628,0.000068063775,0.000017032684,0.00009916035,0.000025250936,0.000089692825,0.99647266,0.00024655473,0.0001524938,0.0019733768],"study_design_scores_gemma":[0.00043607812,0.00069782883,0.005155846,0.000041381518,0.00005992299,0.00061802013,0.000051827727,0.0017645281,0.9820087,0.00029519218,0.008850649,0.000020077985],"about_ca_topic_score_codex":0.00086127647,"about_ca_topic_score_gemma":0.0014282356,"teacher_disagreement_score":0.0035560422,"about_ca_system_score_codex":0.00048424953,"about_ca_system_score_gemma":0.00043172474,"threshold_uncertainty_score":0.011896133},"labels":[],"label_agreement":null},{"id":"W2110045630","doi":"10.1172/jci68760","title":"Multicolor microRNA FISH effectively differentiates tumor types","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; Eidgenössische Technische Hochschule Zürich; National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center; Universität Basel; Howard Hughes Medical Institute","keywords":"microRNA; Biology; Computational biology; Genetics; Gene","score_opus":0.02867407159423965,"score_gpt":0.31889396109713997,"score_spread":0.29021988950290034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110045630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9122166,0.0015296241,0.0798681,0.00021343953,0.000043910684,0.0001716514,0.0004210464,0.0009016765,0.004633967],"genre_scores_gemma":[0.8967209,0.00071192184,0.0979515,0.00016909126,0.000014636246,0.00016650753,0.0004972419,0.0001332496,0.0036349099],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996117,0.000051371302,0.00004055121,0.00016966157,0.00006407698,0.00006273319],"domain_scores_gemma":[0.99968624,0.00012277436,0.00004978865,0.00005342948,0.00005565407,0.000032165288],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006391591,0.00054471433,0.00036176332,0.00062511186,0.00021976637,0.00034562583,0.0002709794,0.00041644904,0.0016351131],"category_scores_gemma":[0.00056947325,0.00032612006,0.00018804308,0.00014631795,0.0003936377,0.00042602952,0.00038461093,0.00038865532,0.0006576571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000109276414,0.000009323674,0.0013959855,0.000033646644,0.0000036870272,0.000027780216,0.000024903806,0.00005693426,0.9941613,0.00006691467,0.000037708483,0.0040726485],"study_design_scores_gemma":[0.000014248949,0.0002417737,0.012103109,0.000008946321,0.000027430935,0.00091169536,0.00005708365,0.0021408086,0.98234266,0.00022112826,0.0019150357,0.000016060174],"about_ca_topic_score_codex":0.0005987946,"about_ca_topic_score_gemma":0.0017444437,"teacher_disagreement_score":0.0016351131,"about_ca_system_score_codex":0.00035136574,"about_ca_system_score_gemma":0.00024543641,"threshold_uncertainty_score":0.005469978},"labels":[],"label_agreement":null},{"id":"W2110358511","doi":"10.1172/jci38399","title":"Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":203,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Rheinische Friedrich-Wilhelms-Universität Bonn; Studienstiftung des Deutschen Volkes; Deutsche Forschungsgemeinschaft","keywords":"Kidney; Renal injury; Medicine; Kidney Glomerulus; Acute kidney injury; Disease; Pathology; Renal stem cell; Glomerulonephritis; Immunology; Biology; Cell biology; Internal medicine; Stem cell","score_opus":0.055665944322037,"score_gpt":0.36494283933955896,"score_spread":0.309276895017522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110358511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907659,0.0013080965,0.0042110756,0.00039286315,0.00008700174,0.00018172537,0.00095614576,0.00038735115,0.0017097834],"genre_scores_gemma":[0.9903391,0.0008032199,0.0030978047,0.00016768492,0.000031291525,0.00025479565,0.0007573951,0.000076055556,0.0044727796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921834,0.00013727658,0.00009528897,0.0001892234,0.00016249939,0.00019731364],"domain_scores_gemma":[0.999305,0.000060010658,0.0001892954,0.00009964631,0.00005706718,0.00028891917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005015664,0.0008361246,0.00071327924,0.0008459621,0.00037382398,0.00070889207,0.00045893763,0.0011584156,0.0016944355],"category_scores_gemma":[0.0002992615,0.00051453785,0.0005919393,0.00031729665,0.0006499645,0.00045584462,0.0003579983,0.0020002334,0.000643203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007259154,0.00037090207,0.0004961654,0.000058866815,0.000012763944,0.00025542648,0.00004997896,0.00013929437,0.99645054,0.00030650038,0.000080682694,0.0010530667],"study_design_scores_gemma":[0.00045125696,0.002587614,0.013495286,0.000057961217,0.00009785616,0.0015193879,0.00010532781,0.005234445,0.969972,0.0004898205,0.0059578726,0.00003109099],"about_ca_topic_score_codex":0.0007942917,"about_ca_topic_score_gemma":0.00091846084,"teacher_disagreement_score":0.0016944355,"about_ca_system_score_codex":0.0008202669,"about_ca_system_score_gemma":0.0006109818,"threshold_uncertainty_score":0.005951464},"labels":[],"label_agreement":null},{"id":"W2110871523","doi":"10.1172/jci37905","title":"CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Barts and The London School of Medicine and Dentistry; Queen Mary University of London; Cancer Research UK; McGill University","keywords":"Oncolytic adenovirus; Oncolytic virus; Cancer cell; Cancer research; Signal transduction; Adenovirus infection; Cancer; Biology; Cell biology; Cell signaling; Carcinogenesis; Cell; Immunology; Virus","score_opus":0.11058973321574131,"score_gpt":0.4406414992173857,"score_spread":0.33005176600164443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110871523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99167013,0.002270385,0.0028383574,0.00020293987,0.0000734016,0.000050850882,0.00023745542,0.00013223267,0.002524172],"genre_scores_gemma":[0.99003196,0.0013792007,0.0034681407,0.00006819909,0.00002344934,0.00004937591,0.0005239241,0.000032859094,0.0044228705],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976355,0.00005948037,0.000026933783,0.000031829324,0.00006324754,0.000054940516],"domain_scores_gemma":[0.99983704,0.000047356087,0.000028270899,0.000028445442,0.000020466729,0.00003843929],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002951456,0.00039404165,0.0003709764,0.00028033683,0.00015899254,0.0004442351,0.00028779177,0.0003497789,0.0013543029],"category_scores_gemma":[0.00023095837,0.00019320175,0.00029088184,0.0001254925,0.00027437723,0.00021119455,0.00020717747,0.00082457135,0.00042185327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011199661,0.000081944956,0.000076372795,0.000030480449,0.000004943082,0.000025370335,0.000017854838,0.000088931825,0.99782914,0.000268494,0.000060322236,0.0014040679],"study_design_scores_gemma":[0.000025579891,0.00055622705,0.00076859025,0.000005392729,0.000011137363,0.0001357852,0.000016096888,0.0019056319,0.9934638,0.000049428047,0.003059504,0.00000269434],"about_ca_topic_score_codex":0.0012537774,"about_ca_topic_score_gemma":0.0014083635,"teacher_disagreement_score":0.0013543029,"about_ca_system_score_codex":0.00036803505,"about_ca_system_score_gemma":0.0003615528,"threshold_uncertainty_score":0.0045306087},"labels":[],"label_agreement":null},{"id":"W2111322263","doi":"10.1172/jci46387","title":"Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Center for Research Resources; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Heart and Stroke Foundation of Canada; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"Proinflammatory cytokine; Immunology; Arthritis; Medicine; Inflammation; Thrombomodulin; Rheumatoid arthritis; Thrombin; Platelet","score_opus":0.11279735175894229,"score_gpt":0.34992224837424174,"score_spread":0.23712489661529945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111322263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99289966,0.0050583715,0.00059227785,0.00012195017,0.000034724722,0.000011200135,0.00005643177,0.000042168052,0.001183277],"genre_scores_gemma":[0.99708444,0.0013549207,0.0005517366,0.00010817003,0.000045716763,0.000012569953,0.00010683898,0.000010573953,0.0007249834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999793,0.00007099918,0.000020480978,0.00002674588,0.000049739858,0.000039040297],"domain_scores_gemma":[0.9998209,0.000035417506,0.00005156088,0.000017045282,0.000017872097,0.000057246474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025416003,0.0002685074,0.0003245008,0.00038105535,0.00014305784,0.00029535615,0.00009526336,0.0002426149,0.0011534222],"category_scores_gemma":[0.00032188703,0.00012212928,0.00015549437,0.00015650917,0.0002241354,0.0001037035,0.00013119946,0.00044209816,0.00026469879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008247055,0.000088362125,0.0015303124,0.00005071917,0.000017868468,0.00032280182,0.000027943192,0.000025660216,0.9902794,0.00006234543,0.00010529681,0.0066646268],"study_design_scores_gemma":[0.0009128563,0.0076765413,0.3385309,0.000071493814,0.00027325738,0.0068140486,0.00018597607,0.0017539314,0.6325551,0.0005942052,0.010603734,0.00002788227],"about_ca_topic_score_codex":0.00029198907,"about_ca_topic_score_gemma":0.00023793295,"teacher_disagreement_score":0.0011534222,"about_ca_system_score_codex":0.00014985212,"about_ca_system_score_gemma":0.00010308109,"threshold_uncertainty_score":0.0038585663},"labels":[],"label_agreement":null},{"id":"W2112927505","doi":"10.1172/jci32011","title":"Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":170,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Heart, Lung, and Blood Institute; Center for Neuroscience Research; National Institutes of Health; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"Internal medicine; Endocrinology; Sterol regulatory element-binding protein; Stimulation; Knockout mouse; Myocyte; Lipid metabolism; Biology; Cholesterol; Medicine; Receptor; Sterol","score_opus":0.040770399253413005,"score_gpt":0.35072733807042683,"score_spread":0.3099569388170138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112927505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98211783,0.0034520547,0.007854955,0.00019724018,0.00010889677,0.00006458932,0.0027268485,0.00017528304,0.0033022363],"genre_scores_gemma":[0.9668655,0.0025693765,0.014408738,0.00012873569,0.0000139061995,0.00020088765,0.0027143625,0.0001224617,0.012976141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997892,0.000025014373,0.00003314773,0.000067732835,0.00005328888,0.000031718926],"domain_scores_gemma":[0.9998511,0.000022056462,0.0000415369,0.00002718684,0.000016953161,0.000041166673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016693746,0.00029009502,0.00017675053,0.00034656143,0.00023021262,0.0002978108,0.0002563926,0.00031031898,0.0019150194],"category_scores_gemma":[0.00012899002,0.00032412176,0.0002631761,0.00015536338,0.00021667831,0.0001838929,0.00025137558,0.0007162167,0.0009128276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000103393024,0.000005480048,0.00010226421,0.000023146553,0.0000027970345,0.000019366078,0.000018656725,0.000020457444,0.999131,0.000106031526,0.000026967517,0.00044043167],"study_design_scores_gemma":[0.00004572532,0.0002490802,0.0153866215,0.000026770776,0.000030958956,0.00028379544,0.00006249946,0.00078879413,0.9772027,0.00007584898,0.005835438,0.000011724591],"about_ca_topic_score_codex":0.002193688,"about_ca_topic_score_gemma":0.0038015768,"teacher_disagreement_score":0.002193688,"about_ca_system_score_codex":0.00043021617,"about_ca_system_score_gemma":0.00020890441,"threshold_uncertainty_score":0.006406367},"labels":[],"label_agreement":null},{"id":"W2113319733","doi":"10.1172/jci83111","title":"Blood kinetics of Ebola virus in survivors and nonsurvivors","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada","funders":"Ministero della Salute; Department for International Development; Government of the United Kingdom","keywords":"Viremia; Ebola virus; Medicine; Outbreak; Immunology; Internal medicine; Virology; Gastroenterology; Virus","score_opus":0.16122278624035272,"score_gpt":0.4345408877419932,"score_spread":0.2733181015016405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113319733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.999433,0.00020173026,0.00007065761,0.000009202794,0.000001835402,0.0000037613775,0.00007971099,0.0000031131508,0.00019704479],"genre_scores_gemma":[0.9995528,0.00008679445,0.000041978496,0.000008319422,0.0000042772886,0.000005361249,0.00021472923,0.0000017794819,0.000084041945],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99969923,0.00006929152,0.000025879366,0.00006619831,0.00006527301,0.00007418159],"domain_scores_gemma":[0.9984469,0.00041724602,0.00051450776,0.000073719755,0.00019798017,0.000349694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006167232,0.00023868048,0.00035874857,0.0007955858,0.00032386446,0.0006441262,0.00018357004,0.00026627065,0.0011026332],"category_scores_gemma":[0.0030805129,0.00014304201,0.00019970343,0.00040659422,0.00030301328,0.00042905484,0.00036028115,0.00042359473,0.00027237783],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008834295,0.000040416777,0.99337184,0.000011778509,0.000039635346,0.00020065339,0.00024402648,0.00010363452,0.0017663451,0.00002998746,0.0000626173,0.0032455544],"study_design_scores_gemma":[0.0000114956865,0.0011006151,0.99598205,0.000011515799,0.00005186231,0.0007156995,0.00045133565,0.0004988682,0.0008174056,0.000079768564,0.00027141583,0.000008084469],"about_ca_topic_score_codex":0.0015575293,"about_ca_topic_score_gemma":0.0007160116,"teacher_disagreement_score":0.0015575293,"about_ca_system_score_codex":0.00031187726,"about_ca_system_score_gemma":0.00016494555,"threshold_uncertainty_score":0.0036886334},"labels":[],"label_agreement":null},{"id":"W2113484361","doi":"10.1172/jci26020","title":"A molecular chaperone for mitochondrial complex I assembly is mutated in a progressive encephalopathy","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":282,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research; March of Dimes Foundation; Howard Hughes Medical Institute","keywords":"Chaperone (clinical); Protein subunit; Biology; Mitochondrion; Mitochondrial matrix; Enzyme; Genetics; Cell biology; Biochemistry; Medicine; Gene; Pathology","score_opus":0.06430496510117388,"score_gpt":0.3770847807447986,"score_spread":0.3127798156436247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113484361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961836,0.0011788149,0.0012742789,0.00018593202,0.000067169116,0.000019648665,0.00013837419,0.00015645642,0.0007956401],"genre_scores_gemma":[0.99669087,0.00048965815,0.0012567885,0.000079559635,0.000025286037,0.000014523569,0.00039155356,0.000026227102,0.0010255193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999256,0.000015071858,0.000010772553,0.000014100314,0.000019879584,0.000014602365],"domain_scores_gemma":[0.99986684,0.000014990842,0.000033172128,0.0000103802195,0.000021389184,0.000053298154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017483333,0.0005428895,0.00020822074,0.0003377158,0.00023937739,0.0002142531,0.0001884392,0.0003328549,0.0006077448],"category_scores_gemma":[0.00031905482,0.00012935227,0.00013688552,0.00015919445,0.00027060218,0.0001090297,0.00026688087,0.00029660706,0.0005929662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048152774,0.00010331791,0.0069484366,0.00013652578,0.000027437813,0.0061077913,0.0000628901,0.00016283279,0.9791278,0.00029706888,0.0007537775,0.0057906928],"study_design_scores_gemma":[0.00037898673,0.0013370449,0.10553563,0.00011805012,0.00021469442,0.05992525,0.0002149954,0.0059880377,0.80128044,0.00072368176,0.024253132,0.000029992327],"about_ca_topic_score_codex":0.00041307212,"about_ca_topic_score_gemma":0.00025061148,"teacher_disagreement_score":0.0006077448,"about_ca_system_score_codex":0.00025494202,"about_ca_system_score_gemma":0.0001584997,"threshold_uncertainty_score":0.002033174},"labels":[],"label_agreement":null},{"id":"W2113606609","doi":"10.1172/jci7739","title":"IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":307,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"European Commission; Hamilton Health Sciences","keywords":"Osteoprotegerin; Osteoclast; RANKL; Bone resorption; Cathepsin K; Arthritis; Inflammation; Tartrate-resistant acid phosphatase; Osteolysis; Internal medicine; Rheumatoid arthritis; Medicine; Endocrinology; Chemistry; Immunology; Receptor; Surgery","score_opus":0.030029463814174137,"score_gpt":0.3192652753956278,"score_spread":0.2892358115814537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113606609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98507303,0.008797468,0.004144253,0.00020031347,0.00011984786,0.000056946003,0.00014370377,0.00020170923,0.0012626959],"genre_scores_gemma":[0.9864494,0.004187149,0.0045545446,0.000092204195,0.00005731218,0.000078254256,0.00032970094,0.000027376722,0.0042241463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999841,0.000028046321,0.00001681564,0.000020820027,0.00004719136,0.000046078567],"domain_scores_gemma":[0.99992037,0.000008845475,0.00003459592,0.000007547509,0.000007273044,0.000021382231],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014219085,0.00047495725,0.00041729969,0.00039604324,0.00012629261,0.00027706538,0.00018519854,0.00029750797,0.0011823266],"category_scores_gemma":[0.00008232419,0.00014003983,0.00040302964,0.00012959153,0.00030509458,0.00016735264,0.00013629966,0.0007420434,0.0003192864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021647455,0.00009841286,0.00012714262,0.00007534373,0.000008076525,0.00006122989,0.000010698066,0.000047971607,0.996881,0.000060846694,0.000031376265,0.0023813292],"study_design_scores_gemma":[0.00015498545,0.0030428183,0.003208381,0.000023967023,0.00007765071,0.000651121,0.000033080138,0.00065654615,0.98612624,0.00007443052,0.005943362,0.00000735362],"about_ca_topic_score_codex":0.00031704962,"about_ca_topic_score_gemma":0.0005948126,"teacher_disagreement_score":0.0011823266,"about_ca_system_score_codex":0.0001805432,"about_ca_system_score_gemma":0.00025156117,"threshold_uncertainty_score":0.003955245},"labels":[],"label_agreement":null},{"id":"W2113929252","doi":"10.1172/jci15336","title":"A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Elizabeth Glaser Pediatric AIDS Foundation","keywords":"Cell biology; Chemokine; Transcription factor; Biology; T cell; Proinflammatory cytokine; EIF4E; p38 mitogen-activated protein kinases; Effector; MAPK/ERK pathway; Kinase; Inflammation; Translation (biology); Immunology; Immune system; Gene; Messenger RNA; Genetics","score_opus":0.07463683282965859,"score_gpt":0.33247707445285823,"score_spread":0.25784024162319963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113929252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99130744,0.0028949184,0.0028593286,0.00026758228,0.00008569302,0.000022851526,0.0000822511,0.00010771452,0.0023723221],"genre_scores_gemma":[0.99601954,0.00086687354,0.0015478899,0.000057139987,0.00004310381,0.000019634026,0.00008405869,0.000022764032,0.0013390506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998741,0.00003308157,0.000011196962,0.000025973355,0.000021496351,0.0000341801],"domain_scores_gemma":[0.9998522,0.00003342486,0.000044033804,0.000022971013,0.000017271106,0.000030178708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000204909,0.00025945096,0.00022546902,0.00015031752,0.00016587753,0.00039694077,0.00015565578,0.00020838418,0.001398737],"category_scores_gemma":[0.00025223722,0.00012409904,0.00016836628,0.00007265868,0.00031662555,0.00028605826,0.00019355227,0.0004943,0.00041892185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001625094,0.000013500856,0.0000938886,0.000016326505,0.0000010700493,0.00003713216,0.000008442233,0.000030134699,0.99851984,0.000126935,0.000019147803,0.00097102585],"study_design_scores_gemma":[0.000028215873,0.00032253438,0.0036367918,0.0000064726223,0.000009479984,0.00017473873,0.000026412541,0.00058193965,0.99300957,0.00013908367,0.0020596266,0.000005135303],"about_ca_topic_score_codex":0.000065459455,"about_ca_topic_score_gemma":0.00014296565,"teacher_disagreement_score":0.001398737,"about_ca_system_score_codex":0.00023354185,"about_ca_system_score_gemma":0.00011750467,"threshold_uncertainty_score":0.0046792626},"labels":[],"label_agreement":null},{"id":"W2114076955","doi":"10.1172/jci39828","title":"Antiphospholipid antibodies promote leukocyte–endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hypertension Canada","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Heart, Lung, and Blood Institute; Lupus Research Alliance","keywords":"Enos; Immunology; Antibody; VCAM-1; Endothelial stem cell; Thrombosis; Medicine; Cell adhesion molecule; Biology; Internal medicine; ICAM-1; In vitro; Nitric oxide; Nitric oxide synthase; Biochemistry","score_opus":0.056231521937453156,"score_gpt":0.3738694221775349,"score_spread":0.3176379002400817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114076955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905868,0.0022648647,0.0037045607,0.0003206934,0.00006505948,0.00006412674,0.00023188794,0.00027032607,0.0024916257],"genre_scores_gemma":[0.9867155,0.0034186812,0.0036662372,0.00031228585,0.000049096085,0.00013721621,0.00039983698,0.000039277507,0.005262032],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973875,0.000065452,0.000027032935,0.00004191949,0.000062456165,0.0000643654],"domain_scores_gemma":[0.99986076,0.000011807877,0.000059257687,0.000011200336,0.000011327133,0.00004563163],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026695343,0.00081991294,0.0003950954,0.000546996,0.00021420122,0.00042482448,0.00028262276,0.00051931647,0.0014600626],"category_scores_gemma":[0.00014206767,0.00035179476,0.00046090892,0.00015148416,0.00026177717,0.00028992968,0.0002311033,0.0011540591,0.00042052148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050169206,0.00026379336,0.00026236605,0.00005121775,0.000020898833,0.00018144022,0.000017406694,0.00006025678,0.9959045,0.00027118385,0.00010053074,0.0023647067],"study_design_scores_gemma":[0.00041089233,0.0034523644,0.009820151,0.000047451882,0.00014480021,0.0012670239,0.00005458304,0.0019134795,0.9768341,0.00031959583,0.005720308,0.000015301264],"about_ca_topic_score_codex":0.00037923883,"about_ca_topic_score_gemma":0.0006205338,"teacher_disagreement_score":0.0014600626,"about_ca_system_score_codex":0.00025035857,"about_ca_system_score_gemma":0.00019851365,"threshold_uncertainty_score":0.004884422},"labels":[],"label_agreement":null},{"id":"W2114170344","doi":"10.1172/jci13946","title":"Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":377,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; American Diabetes Association","keywords":"Gene isoform; Insulin; Cell biology; Insulin receptor; Metabolism; Signal transduction; Biology; Protein expression; Endocrinology; Internal medicine; Chemistry; Biochemistry; Gene; Medicine; Insulin resistance","score_opus":0.03754071205424967,"score_gpt":0.30479571429140195,"score_spread":0.26725500223715226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114170344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98959655,0.0023603598,0.005311066,0.00011345864,0.000025787827,0.000013477216,0.00024979466,0.00010924955,0.0022203026],"genre_scores_gemma":[0.99088824,0.0018491114,0.0043795607,0.00006792118,0.000023009994,0.00004003473,0.0004830103,0.000046649016,0.0022225117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999902,0.000011043268,0.000007910971,0.00003326212,0.000026508005,0.000019377068],"domain_scores_gemma":[0.9998642,0.00001768182,0.000047444122,0.000014551369,0.000021642616,0.00003441113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012699289,0.00025754093,0.0002303167,0.00022030453,0.00008769512,0.00033286534,0.00018641763,0.00014719016,0.00063022814],"category_scores_gemma":[0.00013947971,0.00017172162,0.000118082244,0.00015121976,0.00016894375,0.00023527462,0.00019145066,0.00036154213,0.00015364193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010124727,0.000009644314,0.0011983551,0.000012792808,0.000002281316,0.00006482897,0.000009079741,0.000036985177,0.99571854,0.00010049644,0.00003634246,0.0027094581],"study_design_scores_gemma":[0.00006681873,0.000439581,0.15762456,0.000017246502,0.00006393301,0.0011349177,0.00008969073,0.0017349478,0.8347764,0.00046511923,0.003572085,0.000014798469],"about_ca_topic_score_codex":0.00020192083,"about_ca_topic_score_gemma":0.0004147775,"teacher_disagreement_score":0.00063022814,"about_ca_system_score_codex":0.00025394495,"about_ca_system_score_gemma":0.0001022862,"threshold_uncertainty_score":0.0021083355},"labels":[],"label_agreement":null},{"id":"W2114923316","doi":"10.1172/jci66108","title":"Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Yale University; National Institutes of Health; Canadian Institutes of Health Research; Alexander von Humboldt-Stiftung; Howard Hughes Medical Institute","keywords":"Lymphocytic choriomeningitis; Biology; Immune system; Chronic infection; T cell; Immunology; Virus; Cytokine; Virology; CD8","score_opus":0.02556665882068959,"score_gpt":0.3044554397596309,"score_spread":0.2788887809389413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114923316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948272,0.0022737128,0.0013522223,0.00009323787,0.000030056548,0.000028903278,0.00014417652,0.000101784484,0.0011486734],"genre_scores_gemma":[0.9959453,0.0010060224,0.0011416579,0.00006361538,0.00003318872,0.00003611232,0.00020849115,0.000016812697,0.0015488053],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998211,0.000028904124,0.000013494815,0.000028544695,0.000027271353,0.00008074812],"domain_scores_gemma":[0.9998211,0.00003274454,0.000047534784,0.000019026404,0.000015357438,0.000064199165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021440147,0.00044180616,0.00028265535,0.0002617797,0.00014133142,0.00049985177,0.00014070171,0.00028213384,0.0010968434],"category_scores_gemma":[0.00014762983,0.00019030007,0.00016308311,0.00011674299,0.00035896548,0.00025712186,0.00024569794,0.0011571065,0.0004555245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027280007,0.000081063634,0.0008894498,0.00004354299,0.0000029702335,0.00012272573,0.000026603035,0.000032668257,0.9964079,0.00004445082,0.00005314458,0.0020225672],"study_design_scores_gemma":[0.00019583742,0.0037235164,0.05937263,0.00006344554,0.000057098237,0.0019939854,0.00019236762,0.0019222429,0.9229989,0.00024253689,0.009223348,0.0000140986385],"about_ca_topic_score_codex":0.00027731934,"about_ca_topic_score_gemma":0.00053736323,"teacher_disagreement_score":0.0010968434,"about_ca_system_score_codex":0.0002770202,"about_ca_system_score_gemma":0.0002671418,"threshold_uncertainty_score":0.0036693215},"labels":[],"label_agreement":null},{"id":"W2114942701","doi":"10.1172/jci17892","title":"Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":458,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Heart, Lung, and Blood Institute; University of Cincinnati; Heart and Stroke Foundation of Canada","keywords":"Phospholamban; Dilated cardiomyopathy; Heart failure; Internal medicine; Cardiomyopathy; Biology; Endocrinology; Null allele; Transplantation; Gene targeting; Cardiac function curve; Endoplasmic reticulum; Phenotype; Cell biology; Medicine; Gene; Genetics","score_opus":0.07356511232142594,"score_gpt":0.39147512189506334,"score_spread":0.3179100095736374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114942701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871262,0.0014944798,0.0060921125,0.00026237217,0.00009152716,0.000060368046,0.0013815504,0.0003189084,0.0031725622],"genre_scores_gemma":[0.9908482,0.0010705926,0.0033505333,0.00012094777,0.000026719887,0.00006593601,0.0015048089,0.00009703534,0.0029152667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997968,0.000031311476,0.0000309605,0.000070630704,0.00004951401,0.000020776502],"domain_scores_gemma":[0.99985945,0.000028553683,0.00004320533,0.000019854248,0.00000819244,0.000040747247],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025444612,0.0005890247,0.00032557704,0.00049928966,0.00016093926,0.00025592762,0.00020109446,0.0005882039,0.0038898252],"category_scores_gemma":[0.00020564318,0.00018658176,0.00020049712,0.00017426911,0.00038344692,0.00019147439,0.0002837221,0.00040870355,0.0011597859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004580384,0.00009092721,0.0011198643,0.00005594346,0.000018425495,0.0024914993,0.000038214977,0.00007857734,0.99166006,0.00048390866,0.00021177997,0.003292701],"study_design_scores_gemma":[0.00032045678,0.0014748037,0.03271283,0.00006630167,0.00014153072,0.056436356,0.000091086236,0.0017381312,0.88430023,0.0008774021,0.021802578,0.000038224098],"about_ca_topic_score_codex":0.00014097124,"about_ca_topic_score_gemma":0.00020441916,"teacher_disagreement_score":0.0038898252,"about_ca_system_score_codex":0.00016452302,"about_ca_system_score_gemma":0.00013483324,"threshold_uncertainty_score":0.013012767},"labels":[],"label_agreement":null},{"id":"W2115028037","doi":"10.1172/jci21739","title":"Src promotes estrogen-dependent estrogen receptor α proteolysis in human breast cancer","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"University of Toronto; Sylvester Comprehensive Cancer Center, University of Miami Health Systems; University of Miami; U.S. Department of Defense","keywords":"Estrogen receptor alpha; Estrogen receptor; Proto-oncogene tyrosine-protein kinase Src; Estrogen; Cancer research; Estrogen receptor beta; Biology; Alpha (finance); Proteolysis; Endocrinology; Internal medicine; Chemistry; Cell biology; Signal transduction; Breast cancer; Cancer; Medicine; Biochemistry","score_opus":0.02601182302584698,"score_gpt":0.35904510422416996,"score_spread":0.333033281198323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115028037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9837536,0.011049515,0.00085690833,0.00017502849,0.00004272083,0.000029269782,0.000320255,0.000068186164,0.0037045614],"genre_scores_gemma":[0.989408,0.0047416966,0.0009048501,0.00009538582,0.000031897394,0.000023876632,0.0009810114,0.00000946053,0.0038038578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999058,0.000018843797,0.000008323726,0.000012871167,0.000032923523,0.000021177035],"domain_scores_gemma":[0.99992144,0.000015593632,0.00001733693,0.000010108626,0.000015920947,0.000019555702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016539915,0.00014200048,0.00020138035,0.00015377208,0.0001045347,0.00021842046,0.00006865889,0.00010896474,0.0011629637],"category_scores_gemma":[0.00016700132,0.000112074864,0.00013533974,0.00017684646,0.00011346049,0.00007110919,0.00013065936,0.00023277671,0.0005152794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068863283,0.00009677798,0.0034109883,0.00011704966,0.000018353267,0.00034732436,0.00002999855,0.00008161329,0.98245794,0.00009430164,0.00058388384,0.012073078],"study_design_scores_gemma":[0.00014943222,0.0014844456,0.21696667,0.000025834239,0.00007886707,0.005840148,0.00009412401,0.0013476214,0.7548818,0.0001878953,0.018934088,0.000009096094],"about_ca_topic_score_codex":0.00034315276,"about_ca_topic_score_gemma":0.0007371928,"teacher_disagreement_score":0.0011629637,"about_ca_system_score_codex":0.0001791422,"about_ca_system_score_gemma":0.00016989654,"threshold_uncertainty_score":0.0038905144},"labels":[],"label_agreement":null},{"id":"W2115883095","doi":"10.1172/jci32865","title":"Curcumin prevents and reverses murine cardiac hypertrophy","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Western University; St. Boniface Hospital; Canadian Institutes of Health Research; Heart and Stroke Foundation; Toronto General Hospital; University of Toronto; University Health Network","funders":"Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research; University of Toronto; University of Manitoba; Heart and Stroke Foundation of Canada","keywords":"Curcumin; Cardiac fibrosis; Muscle hypertrophy; Fibrosis; Acetylation; Histone; P300-CBP Transcription Factors; Chromatin remodeling; Biology; Endocrinology; Cancer research; Internal medicine; Chemistry; Pharmacology; Medicine; Histone Acetyltransferases; Biochemistry; Gene","score_opus":0.053037861889708666,"score_gpt":0.3459457015914629,"score_spread":0.2929078397017542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115883095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860153,0.0044240966,0.0035932611,0.00052206026,0.0002005686,0.00013305587,0.00045756352,0.0009183544,0.00373575],"genre_scores_gemma":[0.98701155,0.003475019,0.0022406226,0.00023794993,0.00006468535,0.00012026364,0.0006928388,0.000084440384,0.0060727284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998549,0.00002949916,0.000015781845,0.000021549675,0.000029460081,0.000048805297],"domain_scores_gemma":[0.9997807,0.000034077348,0.000056525376,0.000031845353,0.000025651081,0.000071242954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022624532,0.00066552596,0.00049610384,0.000575047,0.00019474163,0.0002195804,0.00025944997,0.00040708928,0.0015864696],"category_scores_gemma":[0.00023380943,0.00025203027,0.00029432395,0.00011648334,0.00033241184,0.00024343029,0.00025866035,0.001095127,0.0004189123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013740067,0.0007756948,0.00029008993,0.00020701149,0.000032637516,0.00011533292,0.000025898322,0.00016225291,0.98635197,0.00018497695,0.0003650266,0.010115038],"study_design_scores_gemma":[0.00059844885,0.007912679,0.008648253,0.00006991584,0.00011011963,0.00043512014,0.000053301384,0.001098477,0.97297466,0.00027958362,0.007797976,0.000021379283],"about_ca_topic_score_codex":0.00088643597,"about_ca_topic_score_gemma":0.0018368127,"teacher_disagreement_score":0.0015864696,"about_ca_system_score_codex":0.0003002818,"about_ca_system_score_gemma":0.0004798431,"threshold_uncertainty_score":0.005307257},"labels":[],"label_agreement":null},{"id":"W2115985004","doi":"10.1172/jci17038","title":"Randall’s plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kidney Stones and Urolithiasis Treatments","field":"Medicine","cited_by":612,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Basement membrane; Medicine; Kidney stones; Calcium; Anatomy; Pathology; Urology; Internal medicine","score_opus":0.03936582350563315,"score_gpt":0.33095617237809266,"score_spread":0.2915903488724595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115985004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99906594,0.00023343162,0.00017958829,0.000017519382,0.000002130706,0.000008281475,0.000008585288,0.000005375472,0.00047916113],"genre_scores_gemma":[0.9994242,0.00007672312,0.00033148858,0.000010851951,0.0000069628227,0.0000031195311,0.000016417567,0.0000016944525,0.0001287251],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997904,0.000047868638,0.00002493012,0.000053928772,0.000045917135,0.00003708316],"domain_scores_gemma":[0.99952185,0.00009388554,0.0002148258,0.00004422586,0.000044637258,0.00008051328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033341543,0.00032498318,0.0003366813,0.0007758744,0.00045364257,0.00029193144,0.00013463091,0.00034455463,0.0015707143],"category_scores_gemma":[0.0009947816,0.00020858197,0.00021152526,0.00028766887,0.00038570474,0.0004895833,0.00033369623,0.00026716193,0.00018724262],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001997889,0.000127066,0.88170904,0.00013085543,0.00007689521,0.013055448,0.0013405924,0.00009888448,0.08971667,0.00045766626,0.00012615064,0.011162855],"study_design_scores_gemma":[0.000042157855,0.00093307276,0.9316809,0.000016185782,0.00008634752,0.044198323,0.0006466403,0.00024621966,0.02084018,0.0003643721,0.0009280998,0.000017630413],"about_ca_topic_score_codex":0.00044632982,"about_ca_topic_score_gemma":0.000519735,"teacher_disagreement_score":0.0015707143,"about_ca_system_score_codex":0.00009117966,"about_ca_system_score_gemma":0.00014269544,"threshold_uncertainty_score":0.005254507},"labels":[],"label_agreement":null},{"id":"W2117011155","doi":"10.1172/jci29383","title":"Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and inlivers of parabiotic mice","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":671,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; University of Texas Southwestern Medical Center","keywords":"PCSK9; Kexin; LDL receptor; Proprotein convertase; Endocytosis; Biology; Receptor; Cell biology; Endocytic cycle; Internal medicine; Endocrinology; Molecular biology; Cholesterol; Lipoprotein; Biochemistry","score_opus":0.04176156610301236,"score_gpt":0.34578452085656836,"score_spread":0.304022954753556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117011155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907624,0.0017010898,0.00293429,0.0003679759,0.00014856162,0.000045167573,0.0010425621,0.0005076458,0.002490308],"genre_scores_gemma":[0.97289586,0.0013394735,0.0028446838,0.0002918249,0.000064457665,0.000118687356,0.0015664439,0.00028573023,0.020592734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952245,0.000051119485,0.00005257667,0.00013136643,0.00014780436,0.00009475767],"domain_scores_gemma":[0.99917585,0.000059214217,0.00026393775,0.00008282003,0.00006665671,0.00035150227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024003013,0.00082632335,0.0005595899,0.0008579571,0.00023051485,0.00059284526,0.0004063536,0.0006543333,0.0030098583],"category_scores_gemma":[0.00026139285,0.00057874585,0.00044806738,0.0002126719,0.0005105058,0.0003647015,0.0003043825,0.0016778567,0.0011837126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003146674,0.00005602814,0.00020111806,0.000020068917,0.000007183656,0.00006608128,0.000015825332,0.000018269697,0.9986765,0.00006482244,0.00004212774,0.00051732437],"study_design_scores_gemma":[0.00007461889,0.0005563921,0.006852866,0.0000068329555,0.000036332058,0.0003229926,0.000053836047,0.00052136317,0.98990214,0.00007258145,0.0015911448,0.000008913332],"about_ca_topic_score_codex":0.0007592602,"about_ca_topic_score_gemma":0.0010503272,"teacher_disagreement_score":0.0030098583,"about_ca_system_score_codex":0.0005809754,"about_ca_system_score_gemma":0.0002805633,"threshold_uncertainty_score":0.010068953},"labels":[],"label_agreement":null},{"id":"W2117073110","doi":"10.1172/jci9654","title":"A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia; Western University","funders":"National Center for Research Resources; University of Utah; National Cancer Institute; Paralyzed Veterans of America; Muscular Dystrophy Association","keywords":"Mutation; Sodium channel; Periodic paralysis; Mutant; Genetics; Biology; Isoleucine; Leucine; Skeletal muscle; Point mutation; Gene; Paralysis; Chemistry; Endocrinology; Medicine; Sodium; Amino acid","score_opus":0.0441018843422295,"score_gpt":0.31176760768714684,"score_spread":0.26766572334491734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117073110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978022,0.00022979132,0.0008934635,0.00005056947,0.000012837588,0.000014506286,0.00010210006,0.00004711157,0.00084743433],"genre_scores_gemma":[0.99828845,0.00016813204,0.00080022897,0.00004496785,0.000029527699,0.000014941193,0.00017210933,0.000022530383,0.0004589976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975175,0.000035344474,0.000025130143,0.00009506891,0.00005261522,0.000040094175],"domain_scores_gemma":[0.9997304,0.0000627139,0.00008512569,0.000020312224,0.000020389272,0.00008109407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014058423,0.0012982355,0.0004997494,0.00094022515,0.0004016638,0.00033940937,0.00025646546,0.0006370179,0.0021250856],"category_scores_gemma":[0.00068501564,0.00028349497,0.00031087772,0.0004794471,0.00055681897,0.00025592736,0.0005114312,0.00037212402,0.00040390546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027507148,0.00040276675,0.16939384,0.00013864505,0.0002164328,0.29274067,0.0016208004,0.00058313826,0.49126366,0.0013697458,0.0014400706,0.038079415],"study_design_scores_gemma":[0.0002097568,0.0009334877,0.2488822,0.000046206213,0.00019254883,0.7216859,0.00036088418,0.0016009877,0.021317769,0.00069294684,0.004010153,0.00006722092],"about_ca_topic_score_codex":0.0007351324,"about_ca_topic_score_gemma":0.00081510027,"teacher_disagreement_score":0.0021250856,"about_ca_system_score_codex":0.00021221048,"about_ca_system_score_gemma":0.00015492075,"threshold_uncertainty_score":0.0071091056},"labels":[],"label_agreement":null},{"id":"W2117198005","doi":"10.1172/jci24225","title":"The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Leukemia; Biology; Neuroblastoma RAS viral oncogene homolog; Haematopoiesis; Cancer research; Gene; Signal transduction; Mutation; Genetics; Stem cell","score_opus":0.05203177064518576,"score_gpt":0.38833981176546956,"score_spread":0.3363080411202838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117198005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929299,0.0011940539,0.0028764026,0.00018099509,0.000027165543,0.00015789308,0.00041961492,0.0001911711,0.0020227118],"genre_scores_gemma":[0.9894354,0.0014478443,0.0045044785,0.00016087205,0.000038892325,0.0002708547,0.00087278424,0.000055445624,0.003213508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988605,0.00031863732,0.00009209465,0.00020144193,0.00022585892,0.00030153964],"domain_scores_gemma":[0.9992048,0.00014693913,0.00023881962,0.000100190875,0.000025899099,0.00028345472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00089541083,0.0008716837,0.0006792419,0.0018026353,0.00055768894,0.00068617536,0.00062650256,0.000685905,0.0016388171],"category_scores_gemma":[0.0003422569,0.0006049532,0.00075169554,0.0003693695,0.000866572,0.0005482811,0.0006699807,0.0014598166,0.0006556979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025259356,0.001962355,0.0025511289,0.000109231034,0.00008237474,0.00031682526,0.00014478478,0.00061854447,0.98301345,0.0012372418,0.00032947536,0.007108722],"study_design_scores_gemma":[0.00095581205,0.013594051,0.012467175,0.000066573295,0.00019049308,0.0027397107,0.00010584382,0.0028559442,0.9590524,0.00070739584,0.007234534,0.00003013403],"about_ca_topic_score_codex":0.0006521822,"about_ca_topic_score_gemma":0.0009551075,"teacher_disagreement_score":0.0018026353,"about_ca_system_score_codex":0.0006287762,"about_ca_system_score_gemma":0.0004385942,"threshold_uncertainty_score":0.005482435},"labels":[],"label_agreement":null},{"id":"W2117281169","doi":"10.1172/jci66776","title":"Macrophages eliminate circulating tumor cells after monoclonal antibody therapy","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":270,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Antibody opsonization; Monoclonal antibody; Macrophage; Antibody; Cancer research; Phagocytosis; Biology; Fc receptor; Cancer cell; Immunology; Cancer; In vitro; Opsonin; Biochemistry","score_opus":0.07656958440721645,"score_gpt":0.4197651832695201,"score_spread":0.34319559886230366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117281169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96066266,0.018961117,0.014820925,0.0004911886,0.00025356372,0.00013047413,0.0000968077,0.0003705125,0.004212788],"genre_scores_gemma":[0.9885943,0.0021421257,0.0031643037,0.00026474724,0.000101908474,0.00006348561,0.00013801886,0.000033351324,0.005497805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977845,0.00005534828,0.000009389714,0.000027769034,0.000049353566,0.000079657446],"domain_scores_gemma":[0.9998745,0.0000353767,0.000024244911,0.000016233145,0.00002375684,0.000025987387],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025526623,0.00027296643,0.00048937474,0.00016471751,0.00014566742,0.000266958,0.00018423056,0.00042631882,0.0012805169],"category_scores_gemma":[0.00029446176,0.00010675575,0.00020395039,0.00008335308,0.00016836001,0.000252493,0.00022983168,0.0006186002,0.00053673354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004655921,0.00011874517,0.0007345673,0.00012532162,0.000011628124,0.0003976976,0.00006772856,0.00010751453,0.97821814,0.0004940685,0.00047207653,0.018786846],"study_design_scores_gemma":[0.00012123374,0.0025198173,0.005626492,0.000025949359,0.000055674554,0.0015097996,0.00004257617,0.0018090903,0.9742587,0.00040963048,0.0136133665,0.000007695294],"about_ca_topic_score_codex":0.00037884855,"about_ca_topic_score_gemma":0.000510443,"teacher_disagreement_score":0.0012805169,"about_ca_system_score_codex":0.00024305991,"about_ca_system_score_gemma":0.0002533092,"threshold_uncertainty_score":0.004283726},"labels":[],"label_agreement":null},{"id":"W2117810566","doi":"10.1172/jci39738","title":"Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":174,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; U.S. Public Health Service; Canadian Diabetes Association; Brookdale Foundation; Studienstiftung des Deutschen Volkes; American Heart Association","keywords":"Macrophage migration inhibitory factor; Reperfusion injury; Ischemia; Proinflammatory cytokine; Kinase; MAPK/ERK pathway; Endocrinology; Internal medicine; Medicine; Pharmacology; Cytokine; Biology; Inflammation; Cell biology","score_opus":0.02630644483635825,"score_gpt":0.30163225884544165,"score_spread":0.2753258140090834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117810566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948715,0.0024358141,0.0012416991,0.0001378744,0.000044714678,0.000025987367,0.00006741151,0.00006124165,0.0011138828],"genre_scores_gemma":[0.9970086,0.0007244417,0.0010258638,0.000059056652,0.000027705522,0.000032816322,0.000186303,0.000009480385,0.00092573423],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998908,0.00002668406,0.00000992002,0.000009528869,0.000020940824,0.000042127787],"domain_scores_gemma":[0.99990165,0.000012462994,0.000027361319,0.000012447149,0.00001174402,0.000034262503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021631396,0.00040141537,0.00027993915,0.00015181775,0.00013574104,0.00018470461,0.00016841781,0.00018544648,0.00086693995],"category_scores_gemma":[0.00023119147,0.00008471227,0.00015633152,0.000070014634,0.00020856467,0.00012667602,0.00015306783,0.00049830973,0.00029096002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014092706,0.00018355619,0.00030319107,0.00005685904,0.0000063027646,0.000048217735,0.000015855154,0.00006169766,0.9925714,0.00009318743,0.0001495946,0.005100928],"study_design_scores_gemma":[0.0002610791,0.0032098354,0.0072608343,0.000024529701,0.000035733006,0.00047121514,0.000038418122,0.0011298808,0.98471767,0.000113461516,0.002731161,0.0000062140393],"about_ca_topic_score_codex":0.00027499083,"about_ca_topic_score_gemma":0.00050000666,"teacher_disagreement_score":0.00086693995,"about_ca_system_score_codex":0.00018387343,"about_ca_system_score_gemma":0.00023268463,"threshold_uncertainty_score":0.0029002428},"labels":[],"label_agreement":null},{"id":"W2117908470","doi":"10.1172/jci12877","title":"The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":265,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; University of British Columbia; Deutsche Forschungsgemeinschaft; American Heart Association","keywords":"Monocyte; Chemokine; Endothelium; CCR2; Cell adhesion molecule; Chemotaxis; Immunology; Biology; Cell biology; Chemokine receptor; Medicine; Inflammation; Receptor; Endocrinology; Internal medicine","score_opus":0.12162979325214075,"score_gpt":0.3830032502937111,"score_spread":0.26137345704157033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117908470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934669,0.0034404665,0.001213443,0.0000777479,0.00002750309,0.000022586433,0.0001779019,0.00004412503,0.001529382],"genre_scores_gemma":[0.9937109,0.00213165,0.0014953729,0.000072788425,0.0000238714,0.000024037206,0.00035519354,0.000012055653,0.0021740496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985754,0.000032181353,0.000009993144,0.0000162633,0.000021281005,0.000062678766],"domain_scores_gemma":[0.99991715,0.00001855351,0.000015806112,0.000010776869,0.0000120176865,0.000025614929],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013710902,0.00023222693,0.00022030473,0.00011733539,0.00011953667,0.00026182737,0.00010456462,0.00017555783,0.0014742791],"category_scores_gemma":[0.00014684741,0.00007871168,0.0000960283,0.000079098434,0.00015886434,0.0001356709,0.00011153189,0.0003396044,0.00069954613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024543863,0.000037076617,0.00028948105,0.000030277506,0.0000022895772,0.000049914746,0.000015792584,0.000011352193,0.9976065,0.00006496546,0.00007710668,0.0015697837],"study_design_scores_gemma":[0.000045703775,0.0010137776,0.014860452,0.000011010345,0.0000163315,0.0011787968,0.000042081523,0.0003899685,0.9795314,0.000047455113,0.0028567899,0.0000063019224],"about_ca_topic_score_codex":0.00039819142,"about_ca_topic_score_gemma":0.00078264,"teacher_disagreement_score":0.0014742791,"about_ca_system_score_codex":0.00020293894,"about_ca_system_score_gemma":0.00017344886,"threshold_uncertainty_score":0.0049319863},"labels":[],"label_agreement":null},{"id":"W2118096986","doi":"10.1172/jci37958","title":"JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcoma","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"University of Toronto; Canadian Institutes of Health Research; Hospital for Sick Children; Monash University","keywords":"Integrin-linked kinase; Rhabdomyosarcoma; Cancer research; Oncogene; Biology; Kinase; Embryonal rhabdomyosarcoma; Alveolar rhabdomyosarcoma; Ectopic expression; Cell biology; Protein kinase A; Sarcoma; Cancer; Cell culture; Medicine; Cell cycle; Pathology; Genetics","score_opus":0.12515471181057022,"score_gpt":0.4412398777346267,"score_spread":0.31608516592405644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118096986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978289,0.00046547482,0.00052440487,0.000027727521,0.0000063443904,0.000010629082,0.00018524997,0.000018115385,0.0009331825],"genre_scores_gemma":[0.9976763,0.0002561383,0.00049645634,0.000013897108,0.000004038735,0.000012567258,0.00035976814,0.0000088917395,0.0011719633],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991393,0.000012370062,0.000011312513,0.00002011595,0.000021545931,0.000020620713],"domain_scores_gemma":[0.99991894,0.000011060943,0.000023582075,0.000008584124,0.000009454747,0.00002842925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107034844,0.00024808862,0.00015028998,0.0002408878,0.00016422162,0.00018074161,0.00010454558,0.00016585809,0.0012731205],"category_scores_gemma":[0.00010794812,0.00015089712,0.0001682658,0.00008618513,0.00019370716,0.00011816908,0.00016012095,0.00023919807,0.00055339676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008593947,0.000010190039,0.0005291372,0.000014806807,0.0000017675155,0.00007863922,0.000014334288,0.000031787753,0.9987446,0.000102898375,0.000014646604,0.00037110722],"study_design_scores_gemma":[0.000015894895,0.00017014942,0.021931857,0.0000063747184,0.000017195267,0.0014829612,0.000064059,0.00095974165,0.973042,0.00014968195,0.0021531046,0.000007003249],"about_ca_topic_score_codex":0.000486817,"about_ca_topic_score_gemma":0.0006852298,"teacher_disagreement_score":0.0012731205,"about_ca_system_score_codex":0.0002593179,"about_ca_system_score_gemma":0.00018532362,"threshold_uncertainty_score":0.00425905},"labels":[],"label_agreement":null},{"id":"W2118165245","doi":"10.1172/jci58488","title":"Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Alcohol Abuse and Alcoholism; National Key Research and Development Program of China; National High-tech Research and Development Program; Fudan University; Université de Sherbrooke","keywords":"EIF4E; Ribosome biogenesis; Cancer research; Biology; Translation (biology); Ribosomal protein s6; Cell growth; Initiation factor; Internal ribosome entry site; Downregulation and upregulation; Hepatocellular carcinoma; Protein biosynthesis; Kinase; Ribosome; Cell biology; Protein kinase A; Molecular biology; Messenger RNA; RNA; Protein phosphorylation; Genetics; Gene","score_opus":0.049031260022167365,"score_gpt":0.3176034808534566,"score_spread":0.26857222083128923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118165245","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959008,0.0023845094,0.000273025,0.00011406999,0.000022531074,0.000011726605,0.00012248397,0.000054820288,0.001116108],"genre_scores_gemma":[0.99737155,0.0007294299,0.00013471108,0.000025571268,0.000008891093,0.000016256598,0.00024096588,0.000007362263,0.0014651163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994683,0.0000117067875,0.00000415768,0.0000067901365,0.000014950935,0.000015576818],"domain_scores_gemma":[0.9999554,0.000006749804,0.000011456515,0.0000054847105,0.000007043703,0.000013912871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010321299,0.00015377208,0.00019575997,0.00029446543,0.00021194496,0.0001796821,0.00006023042,0.000122851,0.0015556025],"category_scores_gemma":[0.00010195831,0.0001298357,0.000119292876,0.00018884805,0.00011686472,0.00008058788,0.00012648097,0.00024496604,0.00039491864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006818554,0.00009069219,0.002639856,0.000064433545,0.000010543242,0.00024671908,0.000052962223,0.00011309959,0.99242944,0.000143092,0.00034516677,0.0031821975],"study_design_scores_gemma":[0.00013641317,0.0015244266,0.15876701,0.000013868186,0.000077441466,0.0022198148,0.00023221954,0.0031633805,0.82314265,0.0002269122,0.010473276,0.000022570886],"about_ca_topic_score_codex":0.00093051995,"about_ca_topic_score_gemma":0.0010961859,"teacher_disagreement_score":0.0015556025,"about_ca_system_score_codex":0.00022296564,"about_ca_system_score_gemma":0.00017039102,"threshold_uncertainty_score":0.0052039623},"labels":[],"label_agreement":null},{"id":"W2118384803","doi":"10.1172/jci13397","title":"The multiple contributions of thyroid hormone to heat production","year":2001,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Homeothermy; Poikilotherm; Facultative; Thermogenesis; Thermoregulation; Set point; Thermodynamics; Biology; Chemistry; Ecology; Endocrinology; Physics","score_opus":0.06377023524449853,"score_gpt":0.32464146219659706,"score_spread":0.2608712269520985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118384803","genre_codex":"review","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16377938,0.45052055,0.0067747845,0.30430382,0.020715002,0.00013587982,0.00036275142,0.00028657462,0.05312132],"genre_scores_gemma":[0.7441465,0.13831139,0.0021829773,0.043656155,0.052821986,0.00011526939,0.00012695484,0.00006855613,0.018570326],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99966645,0.00009629249,0.00003176437,0.00005236735,0.0000880449,0.000065022476],"domain_scores_gemma":[0.9990671,0.0005889699,0.00006760998,0.00007950002,0.00010611143,0.000090681635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004416885,0.0003443325,0.0008511961,0.0003389376,0.0003858416,0.0008792694,0.00049846934,0.0020850683,0.0027240536],"category_scores_gemma":[0.0020495816,0.00022885532,0.0004405414,0.00035992634,0.0009788008,0.0006915346,0.00037803143,0.0025107826,0.0012300729],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0063357223,0.00042329766,0.048348922,0.0038669298,0.00039681752,0.12747146,0.0009783136,0.001887324,0.10544832,0.025039997,0.1403944,0.53940845],"study_design_scores_gemma":[0.001592327,0.0019571355,0.09422355,0.0013548551,0.0005133978,0.22976857,0.0013063252,0.005018205,0.042228177,0.053188667,0.56861115,0.00023753868],"about_ca_topic_score_codex":0.0016007631,"about_ca_topic_score_gemma":0.002004864,"teacher_disagreement_score":0.0027240536,"about_ca_system_score_codex":0.0019224543,"about_ca_system_score_gemma":0.0005147054,"threshold_uncertainty_score":0.0139485},"labels":[],"label_agreement":null},{"id":"W2118719488","doi":"10.1172/jci44972","title":"Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome–associated PTPN11 mutation","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":277,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto; Princess Margaret Cancer Centre","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Ontario Ministry of Health and Long-Term Care; Howard Hughes Medical Institute","keywords":"PTPN11; Noonan syndrome; Protein tyrosine phosphatase; Hypertrophic cardiomyopathy; Biology; Endocrinology; PI3K/AKT/mTOR pathway; Cancer research; MAPK/ERK pathway; Mutation; PTEN; Internal medicine; Cardiomyopathy; Cell biology; Medicine; Signal transduction; Genetics; Heart failure; Gene","score_opus":0.08745430573202027,"score_gpt":0.31590852145088943,"score_spread":0.22845421571886915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118719488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98905635,0.0017150134,0.0034375766,0.00070198387,0.00031126855,0.00019993169,0.0014853942,0.0007225129,0.0023700048],"genre_scores_gemma":[0.98462117,0.0016685118,0.005110844,0.00042685185,0.00009041182,0.00044127146,0.001968124,0.000101558355,0.005571418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996779,0.000070273556,0.000049034712,0.000072403745,0.000060363156,0.000070043454],"domain_scores_gemma":[0.99969554,0.000038977563,0.00009598182,0.000028625038,0.00002411024,0.00011683054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035340205,0.0009592167,0.00058607705,0.0006719515,0.00030222302,0.0002824719,0.00047769104,0.0010968199,0.0015155785],"category_scores_gemma":[0.00017447195,0.0003746304,0.00045534436,0.00020659239,0.000492428,0.00034211497,0.00019933455,0.0015778826,0.0005490015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072969316,0.0004201948,0.0002807169,0.000084932566,0.000025915844,0.00029283063,0.000024969819,0.00019121442,0.99575436,0.00023052987,0.00026661134,0.0016981631],"study_design_scores_gemma":[0.0009006851,0.008303271,0.012057568,0.00006847778,0.00015825828,0.002461128,0.0001341707,0.00637856,0.9619874,0.00030727568,0.007202441,0.00004071174],"about_ca_topic_score_codex":0.00072622177,"about_ca_topic_score_gemma":0.0013908282,"teacher_disagreement_score":0.0015155785,"about_ca_system_score_codex":0.0004127151,"about_ca_system_score_gemma":0.00041626548,"threshold_uncertainty_score":0.0050700903},"labels":[],"label_agreement":null},{"id":"W2118765054","doi":"10.1172/jci34371","title":"High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Washington","keywords":"Genetic enhancement; Viral vector; Leukemia; Biology; Cancer research; Transgene; Transplantation; Vector (molecular biology); Stem cell; Myeloid; Gene knockdown; Myeloid leukemia; Virology; Murine leukemia virus; Gammaretrovirus; Immunology; Cell culture; Medicine; Gene; Genetics; Internal medicine","score_opus":0.053484268265918324,"score_gpt":0.3462642771937446,"score_spread":0.29278000892782624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118765054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830851,0.0018415772,0.009892743,0.00022616312,0.00007922062,0.00021415083,0.00055214716,0.00049633806,0.0036125982],"genre_scores_gemma":[0.9858898,0.0010638558,0.0042389487,0.00018469148,0.000043540014,0.00023141853,0.0014831139,0.00011157113,0.0067531574],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992415,0.00014925245,0.00006551135,0.00019944357,0.0002262845,0.000117968],"domain_scores_gemma":[0.99881077,0.00032177032,0.0002665055,0.00025069178,0.00008976466,0.0002605604],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067158625,0.00041306895,0.0004849954,0.0011127514,0.0003083078,0.00066162617,0.00030262495,0.0009222118,0.0025890244],"category_scores_gemma":[0.00047731557,0.00024090389,0.0004230562,0.00030424265,0.0005314398,0.00052430463,0.00039725268,0.0013933032,0.0010421055],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004923177,0.00035393267,0.0048537217,0.00006916276,0.000037141275,0.00085577945,0.00011182595,0.00014653434,0.98656344,0.0006086639,0.0003329321,0.0055745905],"study_design_scores_gemma":[0.0001718298,0.00794791,0.03432564,0.0000703853,0.00014042525,0.012611197,0.00020216919,0.0032798825,0.92583126,0.00068118906,0.014693395,0.000044707886],"about_ca_topic_score_codex":0.00021219853,"about_ca_topic_score_gemma":0.00026313067,"teacher_disagreement_score":0.0025890244,"about_ca_system_score_codex":0.00041143017,"about_ca_system_score_gemma":0.00022803503,"threshold_uncertainty_score":0.008661151},"labels":[],"label_agreement":null},{"id":"W2118852930","doi":"10.1172/jci28277","title":"A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Multiple Sclerosis Society; University of California Davis School of Medicine; National Multiple Sclerosis Society","keywords":"Experimental autoimmune encephalomyelitis; Immunology; Multiple sclerosis; Biology; Repertoire; Spleen; Myelin basic protein; Lymph; T cell; Immunization; Myelin; Neuroscience; Medicine; Immune system; Central nervous system; Pathology","score_opus":0.05858409325426539,"score_gpt":0.3137709818482216,"score_spread":0.2551868885939562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118852930","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986626,0.0002131195,0.00041864184,0.000011482606,0.0000023026091,0.000005946223,0.00004243287,0.000020333744,0.0006231687],"genre_scores_gemma":[0.9990031,0.0001341397,0.00031386092,0.000014524341,0.000007588754,0.0000062681693,0.00010953573,0.000007926429,0.0004029483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973685,0.000036537556,0.000012937572,0.00003539434,0.000069311245,0.00010889028],"domain_scores_gemma":[0.9997662,0.000035800622,0.00005969864,0.000031053525,0.00002473254,0.00008245069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020777115,0.00026351982,0.0002308648,0.0003030121,0.00017125641,0.00031832166,0.000115509196,0.00023305272,0.0009883407],"category_scores_gemma":[0.0002042372,0.00017211423,0.000121223246,0.00011165128,0.00021094762,0.00019043256,0.00026293707,0.00045807005,0.00031942036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014908602,0.000050255025,0.0033800032,0.000017654083,0.000003334281,0.00009362355,0.000016801889,0.000036415404,0.9949302,0.00006630052,0.000018264805,0.0012380487],"study_design_scores_gemma":[0.000116602445,0.0026518062,0.15990087,0.0000619565,0.00012844875,0.006452224,0.00023801601,0.0029105362,0.8235505,0.0006122001,0.0033572938,0.000019506937],"about_ca_topic_score_codex":0.0002542759,"about_ca_topic_score_gemma":0.0007105857,"teacher_disagreement_score":0.0009883407,"about_ca_system_score_codex":0.00018896801,"about_ca_system_score_gemma":0.00018253866,"threshold_uncertainty_score":0.0033063293},"labels":[],"label_agreement":null},{"id":"W2119167266","doi":"10.1172/jci32567","title":"TNF-α is critical for antitumor but not antiviral T cell immunity in mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute; University of Toronto; Terry Fox Foundation; Campbell Family Institute for Breast Cancer Research","keywords":"Tumor necrosis factor alpha; Immunology; Immune system; Immunity; Inflammation; TLR2; Cytokine; Priming (agriculture); T cell; Acquired immune system; Medicine; Biology; Cancer research; Innate immune system","score_opus":0.06735948535393264,"score_gpt":0.38258413756802007,"score_spread":0.3152246522140874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119167266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96704537,0.00943408,0.008369894,0.0011697838,0.00027888178,0.00022162245,0.0018718978,0.0009551769,0.01065329],"genre_scores_gemma":[0.9770627,0.0034837937,0.006209622,0.00046426803,0.00011870109,0.00021966806,0.0013616788,0.00023095935,0.010848566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991259,0.00024298826,0.000109701934,0.00016543028,0.00017297656,0.00018310187],"domain_scores_gemma":[0.99873656,0.00018074433,0.00044994496,0.00020558805,0.00007104371,0.00035614896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074426824,0.0010485937,0.0006341829,0.0011429399,0.00045650493,0.001249547,0.00065187743,0.0012076027,0.003065439],"category_scores_gemma":[0.0004934864,0.0008870769,0.00060993445,0.00034552862,0.00090673374,0.00082795415,0.00047155426,0.0024918113,0.002017192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009998581,0.00018760054,0.00028419975,0.00007741859,0.000017867771,0.0002316076,0.000040049374,0.0001240392,0.9948258,0.00064035325,0.0001514043,0.0024197362],"study_design_scores_gemma":[0.00054070144,0.002269879,0.0057673356,0.00011885553,0.00008813048,0.0030963111,0.00009795288,0.0021277966,0.9705687,0.001037676,0.014265849,0.000020849444],"about_ca_topic_score_codex":0.00037911232,"about_ca_topic_score_gemma":0.0004262414,"teacher_disagreement_score":0.003065439,"about_ca_system_score_codex":0.0008250476,"about_ca_system_score_gemma":0.00051428116,"threshold_uncertainty_score":0.0102549195},"labels":[],"label_agreement":null},{"id":"W2119374840","doi":"10.1172/jci35891","title":"Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":272,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Institute in Oncology and Hematology","funders":"National Center for Research Resources; National Eye Institute; National Institutes of Health; Deutsches Krebsforschungszentrum","keywords":"Morphogenesis; Biology; Cell biology; Mutant; Retina; Macular degeneration; Retinal degeneration; Genetics; Gene; Neuroscience; Medicine; Ophthalmology","score_opus":0.027987413645094363,"score_gpt":0.2913927393811662,"score_spread":0.26340532573607184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119374840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974956,0.00052031875,0.0009949397,0.00014256992,0.000013457266,0.000020688276,0.00016763457,0.000102801554,0.0005419951],"genre_scores_gemma":[0.9981213,0.00022352961,0.00091650547,0.000053839973,0.000018072113,0.000011797805,0.0001411243,0.000016798347,0.0004969459],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997873,0.000033479155,0.000023703536,0.00007704139,0.000046955436,0.000031503587],"domain_scores_gemma":[0.99977607,0.00003581826,0.000116057454,0.000012199327,0.000010103456,0.00004966294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023447024,0.0010268604,0.0004695307,0.0012063392,0.000565616,0.00038268737,0.00024992498,0.00078053033,0.0019795396],"category_scores_gemma":[0.00041956492,0.00035655775,0.0003695826,0.00042054235,0.00064116763,0.00025287076,0.0004757747,0.00046250326,0.00035376794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018431414,0.00022955608,0.03184315,0.0001375514,0.00014923402,0.043165524,0.0005015864,0.00034523706,0.90718466,0.001090758,0.00075159804,0.012757971],"study_design_scores_gemma":[0.0007686069,0.0025366095,0.43373257,0.00012196644,0.00073761004,0.29602477,0.0005735699,0.005580097,0.24729684,0.0019788244,0.010540404,0.00010806081],"about_ca_topic_score_codex":0.00086625543,"about_ca_topic_score_gemma":0.00076838525,"teacher_disagreement_score":0.0019795396,"about_ca_system_score_codex":0.00033318886,"about_ca_system_score_gemma":0.00020665662,"threshold_uncertainty_score":0.0066221952},"labels":[],"label_agreement":null},{"id":"W2119791968","doi":"10.1172/jci30767","title":"HPV vaccine gets a shot in the arm","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; HPV vaccines; Cervical cancer; Gardasil; Measles; Family medicine; Vaccination; Measles-Mumps-Rubella Vaccine; Legislation; Rubella; Promiscuity; Rubella vaccine; Virology; HPV infection; Political science; Cancer; Law; Psychology","score_opus":0.18497553864569757,"score_gpt":0.47083997417639456,"score_spread":0.28586443553069696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119791968","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007431447,0.028022397,0.0024762547,0.45200953,0.14045478,0.00037364932,0.003500111,0.0014142846,0.36431754],"genre_scores_gemma":[0.035251413,0.021242063,0.0041700657,0.44543955,0.02777964,0.0002541299,0.005038286,0.0006182876,0.46020654],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99789375,0.0003238341,0.000118107004,0.00020204754,0.0010837038,0.0003786163],"domain_scores_gemma":[0.997566,0.00042131313,0.00016408836,0.00020306585,0.00095286354,0.0006926335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028693639,0.00062685757,0.0005220228,0.0007287872,0.0019474956,0.004085556,0.0008463878,0.006959972,0.06577279],"category_scores_gemma":[0.008251731,0.00047373216,0.0010251943,0.00041317075,0.0008737851,0.004641749,0.0023557374,0.007831675,0.024176424],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016135156,0.0001219596,0.00084320863,0.00021555898,0.000021908376,0.00024942926,0.00015797094,0.000038688162,0.0014179838,0.008004746,0.8712961,0.11747113],"study_design_scores_gemma":[0.00003258847,0.00013618212,0.00064539484,0.00023329222,0.0000145088425,0.00013803758,0.00009807559,0.000025047668,0.00041544993,0.0014125255,0.9968375,0.000011491939],"about_ca_topic_score_codex":0.0055262977,"about_ca_topic_score_gemma":0.010762335,"teacher_disagreement_score":0.06577279,"about_ca_system_score_codex":0.001512108,"about_ca_system_score_gemma":0.0024790317,"threshold_uncertainty_score":0.22003192},"labels":[],"label_agreement":null},{"id":"W2120421571","doi":"10.1172/jci37515","title":"Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":329,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Arbutus Biopharma (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"RNA interference; Mechanism (biology); Mechanism of action; Cancer research; Cancer; Biology; Action (physics); Small interfering RNA; Computational biology; Cell biology; Bioinformatics; Chemistry; RNA; Genetics; Gene; In vitro","score_opus":0.11322939770760516,"score_gpt":0.40136410980355613,"score_spread":0.288134712095951,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120421571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8394894,0.004314875,0.13006261,0.0014806665,0.00052226754,0.002986814,0.003707117,0.0026047642,0.014831444],"genre_scores_gemma":[0.89311856,0.004893073,0.071841404,0.00046868317,0.00013934296,0.0030436825,0.003926943,0.0006667897,0.021901384],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991636,0.0001555529,0.00010736074,0.00023953557,0.00017734704,0.0001566819],"domain_scores_gemma":[0.99932694,0.00016196282,0.00016446254,0.00011048191,0.00014012972,0.00009596767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013761256,0.0013413517,0.00081564503,0.0016907613,0.0005871609,0.0008488973,0.00092199654,0.0010962161,0.003333298],"category_scores_gemma":[0.00059680955,0.0006524956,0.00072757324,0.00033264328,0.0010018379,0.0009847301,0.00036358123,0.002644612,0.0016973926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023750238,0.00027575047,0.00011689992,0.00010766173,0.00001615583,0.00005764432,0.00009610764,0.00016905068,0.9946379,0.0011265907,0.00019935495,0.0029593357],"study_design_scores_gemma":[0.000058593592,0.0007387098,0.00038767856,0.00001290673,0.000021347,0.00010393092,0.000010714801,0.0011580132,0.99499184,0.000100571466,0.0024083322,0.000007316314],"about_ca_topic_score_codex":0.0013571266,"about_ca_topic_score_gemma":0.001959728,"teacher_disagreement_score":0.003333298,"about_ca_system_score_codex":0.00097083626,"about_ca_system_score_gemma":0.0008364748,"threshold_uncertainty_score":0.011151016},"labels":[],"label_agreement":null},{"id":"W2120817558","doi":"10.1172/jci30630","title":"Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"Cotransporter; Mean corpuscular volume; Red blood cell; Chemistry; Hemoglobin; Internal medicine; Endocrinology; Mean corpuscular hemoglobin concentration; Bumetanide; Red Cell; Molecular biology; Biology; Biochemistry; Medicine; Sodium","score_opus":0.055455921939720494,"score_gpt":0.3594736438894574,"score_spread":0.3040177219497369,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120817558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99180603,0.0005217025,0.004849159,0.00013248698,0.000033224565,0.000037630845,0.0016112307,0.00028177712,0.0007268285],"genre_scores_gemma":[0.9897355,0.00054217485,0.0043918174,0.00011890854,0.000014756205,0.00007802073,0.0014033604,0.00014866305,0.0035668667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997346,0.000039673047,0.000055163102,0.00006702477,0.0000624764,0.000041141782],"domain_scores_gemma":[0.99945825,0.000059812326,0.00021496194,0.000037250622,0.000043857646,0.00018596044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019456977,0.00061418355,0.0003637988,0.0007718318,0.00019873884,0.00031374235,0.0004232742,0.0006193896,0.0018474226],"category_scores_gemma":[0.00022113473,0.00033541216,0.0004099661,0.00018294083,0.0004708217,0.00021705669,0.0004864522,0.00087986485,0.00057474454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015546214,0.000025247055,0.00038456597,0.000029125129,0.000011195099,0.00016741871,0.000021953207,0.00008441068,0.9978961,0.00014232157,0.00005269938,0.0010295007],"study_design_scores_gemma":[0.00017553284,0.0006473369,0.028690893,0.000042869393,0.000100110636,0.0028523395,0.00013794348,0.0033174753,0.95919347,0.00032253054,0.004483134,0.00003636474],"about_ca_topic_score_codex":0.0011384214,"about_ca_topic_score_gemma":0.0015985942,"teacher_disagreement_score":0.0018474226,"about_ca_system_score_codex":0.0002993271,"about_ca_system_score_gemma":0.00025847077,"threshold_uncertainty_score":0.006180227},"labels":[],"label_agreement":null},{"id":"W2121260651","doi":"10.1172/jci45563","title":"Mice overexpressing BAFF develop a commensal flora–dependent, IgA-associated nephropathy","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":278,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; McMaster University; Population Health Research Institute; University of Toronto","funders":"University of Toronto; National Institute of Diabetes and Digestive and Kidney Diseases; Kidney Foundation of Canada; Canadian Institutes of Health Research; Biogen","keywords":"B-cell activating factor; Nephropathy; Immunology; Immunoglobulin A; Immune system; Biology; Renal pathology; Glomerulonephritis; Antibody; B cell; Immunoglobulin G; Endocrinology; Kidney; Diabetes mellitus","score_opus":0.13183882228131202,"score_gpt":0.3688347088072599,"score_spread":0.23699588652594786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121260651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945326,0.00040585297,0.0029823384,0.00014218125,0.000032608325,0.000022250755,0.00029165606,0.00023587761,0.001354625],"genre_scores_gemma":[0.9896868,0.0005749635,0.0035571952,0.00012701224,0.000024923262,0.000046418154,0.000564687,0.0000732745,0.0053447923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997515,0.000034321874,0.00002871767,0.00005727352,0.000061171006,0.0000670229],"domain_scores_gemma":[0.9996275,0.00004787618,0.00011043044,0.00003943847,0.000029227043,0.00014552455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002454542,0.0006121192,0.00026983162,0.0007923069,0.00034931104,0.0004383994,0.00029055754,0.00080779946,0.0021067564],"category_scores_gemma":[0.0001983048,0.00029592268,0.00030801634,0.00023225327,0.00039651772,0.00034819174,0.0002916897,0.00087555405,0.0006467757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025948056,0.000114632356,0.00107818,0.000023610735,0.000010160644,0.00025615,0.00003617474,0.000062756284,0.99664646,0.00026330826,0.00006692538,0.0011819884],"study_design_scores_gemma":[0.00019699344,0.0012632546,0.04756041,0.000042986077,0.00011211776,0.0070837736,0.00020728678,0.00320648,0.9311695,0.00082710874,0.008293761,0.00003632399],"about_ca_topic_score_codex":0.00062792166,"about_ca_topic_score_gemma":0.0010389275,"teacher_disagreement_score":0.0021067564,"about_ca_system_score_codex":0.00029099916,"about_ca_system_score_gemma":0.00022572132,"threshold_uncertainty_score":0.0070477724},"labels":[],"label_agreement":null},{"id":"W2122002065","doi":"10.1172/jci41963","title":"Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":216,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Cryptococcus neoformans; Microbiology; Meningoencephalitis; Blood–brain barrier; Biology; Cryptococcosis; Pathogen; Encephalitis; Immunology; Central nervous system; Virus; Neuroscience","score_opus":0.03541368452398917,"score_gpt":0.3535312973903114,"score_spread":0.31811761286632223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122002065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685958,0.0034122183,0.024230096,0.0003331771,0.00006637421,0.0000882072,0.0008094336,0.00040654946,0.002058144],"genre_scores_gemma":[0.9296245,0.0032100067,0.059289332,0.00025385703,0.000031721007,0.00036156204,0.00082508224,0.00010505851,0.0062988633],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998921,0.000012425588,0.000007566119,0.000029534938,0.000019782168,0.000038643313],"domain_scores_gemma":[0.99986446,0.000025381747,0.000037135273,0.000010142329,0.00002404994,0.000038684022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027664672,0.00057233707,0.00023595283,0.0005728337,0.00020160378,0.00023817718,0.0003473271,0.00074600376,0.00090513297],"category_scores_gemma":[0.000102571306,0.0003077375,0.00029004412,0.00022195475,0.00022307217,0.00029002698,0.00020660876,0.00094402925,0.0002187633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006623529,0.000021067075,0.00009424721,0.000030650364,0.0000037547684,0.000050135917,0.000019179082,0.000046875182,0.99890506,0.00006845576,0.00003551804,0.00065879547],"study_design_scores_gemma":[0.000025892643,0.00036493925,0.005022664,0.000021000842,0.000026817894,0.00033910325,0.000054032054,0.0050023193,0.9880014,0.00009815773,0.0010299908,0.000013605145],"about_ca_topic_score_codex":0.0019471304,"about_ca_topic_score_gemma":0.0026090667,"teacher_disagreement_score":0.0019471304,"about_ca_system_score_codex":0.00030747708,"about_ca_system_score_gemma":0.00029983665,"threshold_uncertainty_score":0.00387156},"labels":[],"label_agreement":null},{"id":"W2122311980","doi":"10.1172/jci31692","title":"CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":623,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"CX3CR1; Macular degeneration; Drusen; Retinal; Microglia; Choroidal neovascularization; Retinal degeneration; Biology; Retina; Pathology; Medicine; Ophthalmology; Chemokine receptor; Chemokine; Immunology; Neuroscience; Inflammation","score_opus":0.06640584605646863,"score_gpt":0.38246104786242296,"score_spread":0.31605520180595437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122311980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971418,0.001476889,0.00075510377,0.000060553448,0.000008374233,0.000016706537,0.00007261149,0.000030444644,0.00043760904],"genre_scores_gemma":[0.9981249,0.00058917335,0.0007196298,0.000030449706,0.00002437015,0.000014715545,0.00008010953,0.0000047129256,0.0004119515],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998528,0.000030056168,0.000018082428,0.00002891287,0.0000438216,0.000026251957],"domain_scores_gemma":[0.9996339,0.00003282939,0.00019890198,0.000035427336,0.000041002626,0.000057887366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017215591,0.00030424006,0.0002695439,0.00054350356,0.00021869178,0.00015187074,0.00008553137,0.00027117683,0.0007749866],"category_scores_gemma":[0.00027859004,0.00011614993,0.00015834288,0.00015220462,0.0002949827,0.00014227982,0.00021467886,0.00035289975,0.0001623906],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069605815,0.000083113155,0.02556156,0.00010778364,0.000027451964,0.0030484388,0.00013800457,0.000046796693,0.96383727,0.00023515522,0.0002554802,0.0059628724],"study_design_scores_gemma":[0.00009833304,0.0010913761,0.65321785,0.00003374401,0.00009023005,0.05602906,0.00019433121,0.0010731615,0.28352422,0.0008438908,0.0037776583,0.000026025116],"about_ca_topic_score_codex":0.00034153427,"about_ca_topic_score_gemma":0.00049194857,"teacher_disagreement_score":0.0007749866,"about_ca_system_score_codex":0.00013222001,"about_ca_system_score_gemma":0.00008935564,"threshold_uncertainty_score":0.0025925636},"labels":[],"label_agreement":null},{"id":"W2122553885","doi":"10.1172/jci24918","title":"Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":277,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital","funders":"Canadian Arthritis Network; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Canadian Institutes of Health Research; Lady Davis Institute for Medical Research; National Cancer Institute; National Institutes of Health; Jewish General Hospital; McGill University","keywords":"Osteoblast; Endocrinology; Anabolism; Internal medicine; Parathyroid hormone; Endogeny; Parathyroid hormone-related protein; Osteoporosis; Bone remodeling; Chemistry; Anabolic Agents; Medicine; Calcium; Biochemistry; In vitro","score_opus":0.25297000598563824,"score_gpt":0.40863365569462096,"score_spread":0.15566364970898272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122553885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99260837,0.0027377976,0.0022885671,0.00020175801,0.000054967168,0.00007583212,0.00029763466,0.0001515605,0.0015835118],"genre_scores_gemma":[0.9927826,0.0017220872,0.0027723946,0.00005451622,0.000030653617,0.00005682885,0.00035622326,0.000019306666,0.0022052692],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998123,0.000034604218,0.000015824742,0.000027410348,0.00007394416,0.000035985682],"domain_scores_gemma":[0.99992096,0.000012841263,0.00002641929,0.000007716004,0.0000044398957,0.000027605654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016426359,0.00036183573,0.00036576623,0.00035231598,0.00010955653,0.0002449296,0.00020431045,0.00040872305,0.0014384708],"category_scores_gemma":[0.00013989728,0.0001823061,0.00015673961,0.0001727105,0.00044420204,0.00016526262,0.00014622965,0.00085197063,0.0003543889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025787318,0.00009543847,0.00008744589,0.00003302741,0.0000039257934,0.000053237516,0.0000060771586,0.0000405961,0.99689376,0.00006060135,0.000048948863,0.002419044],"study_design_scores_gemma":[0.00018621309,0.0039616614,0.003463644,0.000008564748,0.000039266666,0.0009136136,0.00001957376,0.00044365073,0.9873241,0.00007916342,0.0035536664,0.000006750629],"about_ca_topic_score_codex":0.00017236189,"about_ca_topic_score_gemma":0.00034829965,"teacher_disagreement_score":0.0014384708,"about_ca_system_score_codex":0.00015461085,"about_ca_system_score_gemma":0.00016943095,"threshold_uncertainty_score":0.004812181},"labels":[],"label_agreement":null},{"id":"W2122597070","doi":"10.1172/jci46134","title":"PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; McGill University; Susan G. Komen for the Cure; U.S. Department of Defense","keywords":"Metastasis; Tumor progression; Parathyroid hormone-related protein; Cancer research; Cancer; Angiogenesis; Breast cancer; Medicine; Cyclin D1; Internal medicine; Biology; Cell cycle; Parathyroid hormone","score_opus":0.10422920311868719,"score_gpt":0.400679060061798,"score_spread":0.29644985694311077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122597070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95626867,0.012063801,0.015107446,0.0023127492,0.00025015473,0.00026547897,0.0024413478,0.0010088873,0.010281546],"genre_scores_gemma":[0.9707611,0.005032823,0.0073463633,0.00036830633,0.000060405273,0.0002520766,0.0011759956,0.00011180212,0.014891071],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996245,0.00006403858,0.000023076258,0.00007625729,0.00013315358,0.00007891384],"domain_scores_gemma":[0.99983585,0.000017424816,0.00005727059,0.000017737137,0.000014041831,0.000057682464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029440844,0.00043536176,0.00033672273,0.00072887726,0.00024291396,0.0004915009,0.00033588367,0.00062627386,0.0024715483],"category_scores_gemma":[0.00012317463,0.00031656606,0.0003180329,0.00030407013,0.0005763774,0.00034137606,0.00027843312,0.0016865877,0.00054832944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038612782,0.00013396027,0.00018125151,0.000050292438,0.000007908304,0.000069260204,0.000022270975,0.000071973554,0.9949124,0.0005644299,0.0002523722,0.0033475924],"study_design_scores_gemma":[0.00024987807,0.0019541257,0.004171643,0.000030337542,0.0000525469,0.0007534411,0.00006406094,0.0019599237,0.971876,0.0005608093,0.018313965,0.000013184065],"about_ca_topic_score_codex":0.0008864238,"about_ca_topic_score_gemma":0.0014289152,"teacher_disagreement_score":0.0024715483,"about_ca_system_score_codex":0.00061371166,"about_ca_system_score_gemma":0.0004900355,"threshold_uncertainty_score":0.008268118},"labels":[],"label_agreement":null},{"id":"W2122843018","doi":"10.1172/jci36079","title":"Science rides the online wave","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Wikis in Education and Collaboration","field":"Social Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"World Wide Web; The Internet; Subject (documents); Internet privacy; Social media; Web 2.0; Computer science; Public relations; Political science","score_opus":0.27309583261533915,"score_gpt":0.4908213780092017,"score_spread":0.21772554539386257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122843018","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0030904075,0.034262106,0.005082789,0.6239338,0.0461444,0.000055906065,0.0024016711,0.0023535169,0.28267547],"genre_scores_gemma":[0.065477975,0.067234285,0.0048228274,0.38486162,0.07573567,0.00031953753,0.0036298374,0.0031065599,0.3948117],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9951367,0.00088603055,0.00019471307,0.0006231522,0.0025031415,0.0006563956],"domain_scores_gemma":[0.9768404,0.0078999195,0.0014312814,0.003469538,0.004249015,0.006109955],"candidate_categories":["scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.008375046,0.0009196745,0.0011150701,0.004532135,0.007820416,0.018980674,0.002120987,0.009844351,0.15703098],"category_scores_gemma":[0.038125448,0.0006510762,0.0009615339,0.0037495578,0.0073823384,0.04017172,0.012660961,0.012467764,0.07866913],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049285318,0.0000242252,0.00054540584,0.00024451004,0.000017873126,0.000101423226,0.0011526642,0.000038345246,0.00037328264,0.08315259,0.8455436,0.06875664],"study_design_scores_gemma":[0.0000057788347,0.000007752474,0.0001543019,0.0000958551,0.0000031574334,0.00003436665,0.0004528624,0.000021018053,0.000053199637,0.014577725,0.98458606,0.000007982911],"about_ca_topic_score_codex":0.003706705,"about_ca_topic_score_gemma":0.0043723057,"teacher_disagreement_score":0.9810193,"about_ca_system_score_codex":0.002579806,"about_ca_system_score_gemma":0.0057568806,"threshold_uncertainty_score":0.525321},"labels":[],"label_agreement":null},{"id":"W2123366371","doi":"10.1172/jci81676","title":"MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":388,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Ottawa; Bell (Canada)","funders":"National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Canada Research Chairs; National Institute of Allergy and Infectious Diseases; NYU Langone Medical Center; American Heart Association","keywords":"Macrophage polarization; Biology; Inflammation; Cell biology; Immune system; FOXP3; Macrophage; Immunology; Biochemistry","score_opus":0.057737858493259256,"score_gpt":0.31737374082739545,"score_spread":0.2596358823341362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123366371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9645523,0.011785913,0.015777199,0.0006285316,0.00018646137,0.00010016286,0.00059202005,0.00044352366,0.005934001],"genre_scores_gemma":[0.99112576,0.0027636846,0.003883114,0.00013949371,0.00002452347,0.0000496271,0.00021874129,0.00002948311,0.0017655636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998349,0.00004183406,0.000012837745,0.000031925563,0.000038551032,0.00003992542],"domain_scores_gemma":[0.9999219,0.000011683353,0.000026292935,0.000009495655,0.000013854728,0.0000167046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030146044,0.00039791272,0.00025688123,0.0002256006,0.0002274455,0.00031979757,0.00011242187,0.00026770096,0.0011537414],"category_scores_gemma":[0.00016808299,0.0002416725,0.00030191286,0.00013375476,0.00026966163,0.00017390642,0.0003143855,0.00065766525,0.0004999924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001957155,0.000013434541,0.00029324,0.000048041893,0.000005079888,0.000076658645,0.000019615847,0.00009866557,0.9963337,0.00031664985,0.00012245824,0.0024766126],"study_design_scores_gemma":[0.0000474307,0.00037189733,0.013927231,0.000023825376,0.000055052908,0.00065376604,0.00008469722,0.0018716356,0.9698499,0.00048199756,0.012612775,0.000019900355],"about_ca_topic_score_codex":0.0003125759,"about_ca_topic_score_gemma":0.00052742363,"teacher_disagreement_score":0.0011537414,"about_ca_system_score_codex":0.00029268698,"about_ca_system_score_gemma":0.00030039917,"threshold_uncertainty_score":0.0038596392},"labels":[],"label_agreement":null},{"id":"W2124176874","doi":"10.1172/jci64484","title":"Mutant huntingtin impairs immune cell migration in Huntington disease","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":145,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Neurological Disorders and Stroke; Medical Research Council; University of California, San Francisco; National Institutes of Health; Concordia University; University of Leicester; Multiple Sclerosis Society; Gladstone Institutes; National Institute on Drug Abuse; CHDI Foundation","keywords":"Huntingtin; Immune system; Microglia; Biology; Neurodegeneration; Mutant; Huntington's disease; Cell biology; Huntingtin Protein; Immunology; Inflammation; Disease; Genetics; Medicine; Pathology; Gene","score_opus":0.07844389210649401,"score_gpt":0.3546007779199818,"score_spread":0.2761568858134878,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124176874","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989485,0.0005058148,0.00017255505,0.000019520081,0.0000072298385,0.000004580863,0.000024272267,0.000015690257,0.00030173882],"genre_scores_gemma":[0.99811566,0.0005407599,0.00034692965,0.00003702037,0.000005056608,0.000011645233,0.00007947493,0.0000075863168,0.00085585413],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991417,0.000021339725,0.000009442591,0.000012186279,0.000015553242,0.000027348171],"domain_scores_gemma":[0.9999236,0.000011199908,0.000017150907,0.0000058607675,0.0000074264385,0.000034766894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001336603,0.00032200522,0.00021909292,0.0002039813,0.00016817164,0.00017200792,0.00010519358,0.0002607519,0.00058541604],"category_scores_gemma":[0.000112975635,0.00013357442,0.00014219018,0.00006586659,0.00020349992,0.00011342771,0.00016572987,0.00026500862,0.00018167152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002630085,0.000051976524,0.0006180402,0.000017895392,0.00000533155,0.00026111607,0.000030513986,0.000025875404,0.99724966,0.000034068966,0.000039242543,0.0014031962],"study_design_scores_gemma":[0.00015045692,0.002824127,0.12801704,0.00005055889,0.000075663,0.004283253,0.00026368996,0.0015585679,0.8578553,0.00032735523,0.004577942,0.000016090484],"about_ca_topic_score_codex":0.0006613847,"about_ca_topic_score_gemma":0.0011693041,"teacher_disagreement_score":0.0006613847,"about_ca_system_score_codex":0.000181547,"about_ca_system_score_gemma":0.00013389604,"threshold_uncertainty_score":0.0019583702},"labels":[],"label_agreement":null},{"id":"W2124330580","doi":"10.1172/jci32525","title":"Factor I is required for the development of membranoproliferative glomerulonephritis in factor H–deficient mice","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"Imperial College London; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Wellcome Trust","keywords":"Complement factor B; Membranoproliferative glomerulonephritis; Alternative complement pathway; Complement system; Internal medicine; Endocrinology; Complement factor I; Factor H; Immunology; Biology; Glomerulonephritis; Chemistry; Kidney; Medicine; Antibody","score_opus":0.18347465497491608,"score_gpt":0.3869778507815383,"score_spread":0.2035031958066222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124330580","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98994446,0.0016389873,0.0037750744,0.000307312,0.000061016624,0.000054162178,0.0011823718,0.00043076577,0.0026059316],"genre_scores_gemma":[0.99093306,0.00074946665,0.003985836,0.00014267908,0.000037572598,0.000071468756,0.0008668958,0.00017316442,0.0030398637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994266,0.00009139784,0.000072137926,0.00016148709,0.00010909219,0.0001393757],"domain_scores_gemma":[0.9985189,0.00022818924,0.0006113863,0.00011129002,0.000052416795,0.00047791508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030520718,0.0010258338,0.0005275893,0.0014176057,0.0003406774,0.0008786316,0.000633378,0.0013202281,0.0027213737],"category_scores_gemma":[0.0005114217,0.0006366467,0.0005369546,0.000315982,0.0007174812,0.0004898679,0.000474929,0.0014372249,0.0008914223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004364846,0.00010291777,0.0006769996,0.000038771836,0.00001873264,0.00037734178,0.00003581379,0.00011318634,0.9966767,0.00029729056,0.00010509608,0.0011205694],"study_design_scores_gemma":[0.0003364636,0.0010056392,0.025507377,0.000068356014,0.000115610856,0.005334949,0.0001465581,0.0030868733,0.95774424,0.000682024,0.0059238463,0.000047994345],"about_ca_topic_score_codex":0.0007847348,"about_ca_topic_score_gemma":0.00070763595,"teacher_disagreement_score":0.0027213737,"about_ca_system_score_codex":0.0006468299,"about_ca_system_score_gemma":0.00037519942,"threshold_uncertainty_score":0.009103894},"labels":[],"label_agreement":null},{"id":"W2125419124","doi":"10.1172/jci35874","title":"PMNs facilitate translocation of platelets across human and mouse epithelium and together alter fluid homeostasis via epithelial cell–expressed ecto-NTPDases","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Platelet; Intestinal epithelium; Epithelium; Cell biology; Proinflammatory cytokine; Secretion; Intestinal mucosa; Inflammation; Immunology; Biology; Homeostasis; Chemistry; Biochemistry; Medicine; Internal medicine","score_opus":0.059793345842946835,"score_gpt":0.3313944035846833,"score_spread":0.2716010577417365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125419124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9794301,0.00636411,0.00968704,0.00042250464,0.00010139724,0.00008623653,0.00045986215,0.00010819951,0.0033406888],"genre_scores_gemma":[0.98756194,0.0023291714,0.0046343794,0.00014957869,0.000017274779,0.000060036014,0.0005334657,0.000018555027,0.0046954877],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99971634,0.00007157641,0.00002475441,0.00006240356,0.00006496851,0.000059929822],"domain_scores_gemma":[0.9999434,0.000011466695,0.000016134925,0.000009393055,0.0000060173993,0.000013695466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021661406,0.00028754055,0.00023564888,0.00020387144,0.0001410382,0.00042763713,0.00014514873,0.00030310775,0.0020690656],"category_scores_gemma":[0.00014923226,0.00012786668,0.0002692493,0.0001250374,0.00018234365,0.0002727635,0.00025581734,0.0006050483,0.00043334844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022166735,0.000040531377,0.0001174957,0.00004660628,0.0000050376225,0.00009228555,0.000022616408,0.000028465161,0.997451,0.00017466134,0.000059505266,0.0017400978],"study_design_scores_gemma":[0.000037409856,0.00062288035,0.003803752,0.000013400606,0.00001979624,0.0004191629,0.000057501635,0.0007081268,0.9886348,0.00007499984,0.0056042424,0.0000040068808],"about_ca_topic_score_codex":0.00050761044,"about_ca_topic_score_gemma":0.0007923254,"teacher_disagreement_score":0.0020690656,"about_ca_system_score_codex":0.0002327474,"about_ca_system_score_gemma":0.00017094384,"threshold_uncertainty_score":0.0069217086},"labels":[],"label_agreement":null},{"id":"W2125727551","doi":"10.1172/jci44555","title":"Loss of Gata5 in mice leads to bicuspid aortic valve","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Université de Montréal","funders":"Canadian Institutes of Health Research; University of Ottawa; Heart and Stroke Foundation of Canada","keywords":"Bicuspid aortic valve; Cardiology; Medicine; Internal medicine; Aortic valve","score_opus":0.10822361581151572,"score_gpt":0.4072296386962687,"score_spread":0.299006022884753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125727551","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9771209,0.0023207744,0.013069242,0.0005027648,0.00015872096,0.00012515073,0.0020280925,0.00079754187,0.0038768502],"genre_scores_gemma":[0.97633946,0.0013679388,0.010107811,0.0002736441,0.000032121603,0.00015740246,0.0015373323,0.0002668223,0.009917489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992655,0.00013897472,0.00012153353,0.00018034097,0.00016662864,0.00012706165],"domain_scores_gemma":[0.99950993,0.000083764935,0.00016753553,0.00004692625,0.000018609593,0.00017329952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004084101,0.0008672986,0.0003385904,0.0010834818,0.00039880606,0.00050057605,0.00061267195,0.0012917442,0.0041977228],"category_scores_gemma":[0.00028502484,0.0008042763,0.00039733143,0.00028212066,0.0008316823,0.0003551003,0.00059118326,0.0012086625,0.0013405675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034481363,0.00009181579,0.00040961045,0.000060672064,0.00002032938,0.0002887596,0.000058209305,0.00016786909,0.9958711,0.00063160784,0.00013069832,0.0019245187],"study_design_scores_gemma":[0.00033979482,0.0010437332,0.008410075,0.000096776246,0.00011717411,0.0035438682,0.00016851007,0.0039778776,0.9724087,0.0008166014,0.009042204,0.00003467858],"about_ca_topic_score_codex":0.00075215776,"about_ca_topic_score_gemma":0.0015358631,"teacher_disagreement_score":0.0041977228,"about_ca_system_score_codex":0.00046287596,"about_ca_system_score_gemma":0.0002616544,"threshold_uncertainty_score":0.014042735},"labels":[],"label_agreement":null},{"id":"W2125733229","doi":"10.1172/jci41431","title":"Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute; National Institutes of Health; Mayo Foundation for Medical Education and Research","keywords":"Oncolytic virus; Cancer research; Virotherapy; Melanoma; Cancer; Medicine; Viral replication; Immunology; Immune system; Biology; Virus; Internal medicine","score_opus":0.047727150588789465,"score_gpt":0.39777268982086483,"score_spread":0.3500455392320754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125733229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9734172,0.0040029273,0.014562888,0.00040560224,0.0002229483,0.00028975712,0.0007148908,0.0008239559,0.0055598123],"genre_scores_gemma":[0.97384983,0.0034382676,0.011159184,0.0001678667,0.00008150861,0.0002689793,0.0009737109,0.00013718872,0.0099235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952817,0.00009010103,0.000034619803,0.00010516482,0.00013844368,0.000103486615],"domain_scores_gemma":[0.9998,0.000027810845,0.00006064729,0.000035556066,0.000012711004,0.00006319981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003923353,0.00087620463,0.00070695183,0.0008161173,0.00017052251,0.00052212377,0.00044256786,0.00058651075,0.0014736273],"category_scores_gemma":[0.00013351279,0.00034029843,0.0005124679,0.00032824645,0.00049069483,0.00035655874,0.00021088545,0.0018302205,0.0006627464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027326625,0.00045826967,0.0001063576,0.00004159486,0.000018664976,0.000037246187,0.0000277629,0.00020398262,0.9939976,0.00037682324,0.00019554805,0.0042628553],"study_design_scores_gemma":[0.00011505878,0.0025645592,0.0012893963,0.000011951418,0.000030691368,0.00023322801,0.000010288511,0.0018864034,0.98954844,0.000099809346,0.0042027975,0.0000073517094],"about_ca_topic_score_codex":0.00066498894,"about_ca_topic_score_gemma":0.0012744331,"teacher_disagreement_score":0.0014736273,"about_ca_system_score_codex":0.00043590865,"about_ca_system_score_gemma":0.00046067638,"threshold_uncertainty_score":0.004929781},"labels":[],"label_agreement":null},{"id":"W2125774818","doi":"10.1172/jci38433","title":"Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Julius-Maximilians-Universität Würzburg; Universidade do Porto; National Heart, Lung, and Blood Institute; Albert-Ludwigs-Universität Freiburg; Deutsches Krebsforschungszentrum; Deutsche Forschungsgemeinschaft; American Heart Association","keywords":"Blood pressure; Sympathetic nervous system; Endocrinology; Internal medicine; Allele; Stimulation; Phenotype; Medicine; Homeostasis; Catecholamine; Biology; Gene; Genetics","score_opus":0.11119545458172723,"score_gpt":0.3922332784606517,"score_spread":0.28103782387892445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125774818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952118,0.0006922188,0.0021042323,0.00034302444,0.000087306515,0.000055893695,0.00031805888,0.00013174357,0.0010557241],"genre_scores_gemma":[0.99457437,0.0007566913,0.0022910573,0.00015965529,0.000030511283,0.000103616105,0.00033607654,0.000048893602,0.0016991888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997501,0.000065665256,0.000024054618,0.000063316336,0.000039692208,0.000057232264],"domain_scores_gemma":[0.9997682,0.000029094463,0.000068138346,0.00003523537,0.000011076427,0.000088192544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003365887,0.00031951658,0.00028683932,0.00043344926,0.0002199628,0.00039884239,0.00028295437,0.0004320032,0.0015438859],"category_scores_gemma":[0.00023782182,0.00029055894,0.0003065156,0.00013857124,0.00073138665,0.0002172824,0.00028501858,0.00083827844,0.0001920538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018404158,0.00041046453,0.00064478617,0.000052879084,0.000024252608,0.000113248294,0.000043491757,0.00014177152,0.9926696,0.00042968997,0.00018747711,0.0034417994],"study_design_scores_gemma":[0.0015213764,0.009101903,0.02147496,0.00007993652,0.00018977492,0.0010871392,0.0001615144,0.0051307445,0.9513435,0.00079491915,0.009077578,0.000036692385],"about_ca_topic_score_codex":0.00058595446,"about_ca_topic_score_gemma":0.0009080046,"teacher_disagreement_score":0.0015438859,"about_ca_system_score_codex":0.0002414811,"about_ca_system_score_gemma":0.00031264682,"threshold_uncertainty_score":0.005164802},"labels":[],"label_agreement":null},{"id":"W2125864491","doi":"10.1172/jci15183","title":"Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":539,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Center for Research Resources; National Institutes of Health; University of Rochester; National Heart, Lung, and Blood Institute; Muscular Dystrophy Association; Howard Hughes Medical Institute","keywords":"Afterdepolarization; Periodic paralysis; Long QT syndrome; Channelopathy; Internal medicine; Mutation; Medicine; Cardiac arrhythmia; Endocrinology; Myocyte; Cardiology; Biology; QT interval; Electrophysiology; Paralysis; Atrial fibrillation; Genetics; Repolarization; Surgery; Gene","score_opus":0.07382040307457637,"score_gpt":0.3337305183501474,"score_spread":0.259910115275571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125864491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992568,0.00012644033,0.00023581444,0.000014955828,0.0000036062972,0.0000065044605,0.000052552772,0.000005091382,0.00029832975],"genre_scores_gemma":[0.99931645,0.00008187424,0.0003504441,0.000016368618,0.000005106752,0.0000060089546,0.000105216175,0.000004310515,0.000114197675],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998441,0.00003104342,0.000022904766,0.00003069425,0.00004947538,0.00002177798],"domain_scores_gemma":[0.99981683,0.00006231159,0.000035282177,0.000008122093,0.00002750015,0.000049928014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018782339,0.00040820846,0.00021903882,0.0005567534,0.0001484282,0.00016860821,0.00017403497,0.00042617333,0.00092455914],"category_scores_gemma":[0.0006795942,0.00008337391,0.00012595742,0.00016173229,0.0003507294,0.00011057617,0.00021545151,0.00014093603,0.00014080762],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008297872,0.00018384327,0.27381527,0.00012600285,0.00008517897,0.074243985,0.00051396096,0.0006988673,0.6377324,0.0005564397,0.0003044189,0.010909892],"study_design_scores_gemma":[0.00008689703,0.001005464,0.7877403,0.00003974553,0.00011862575,0.16494182,0.00045629984,0.00340833,0.039647035,0.00039331045,0.002130953,0.000031260653],"about_ca_topic_score_codex":0.00075205095,"about_ca_topic_score_gemma":0.00081047305,"teacher_disagreement_score":0.00092455914,"about_ca_system_score_codex":0.00010503721,"about_ca_system_score_gemma":0.000108217435,"threshold_uncertainty_score":0.0030929446},"labels":[],"label_agreement":null},{"id":"W2126444826","doi":"10.1172/jci63818","title":"Taming endothelial activation with a microRNA","year":2012,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"Canadian Institutes of Health Research; Medical Research Council; Australian Government; National Health and Medical Research Council; Heart and Stroke Foundation of Canada","keywords":"Inflammation; microRNA; Regulator; Biology; Signal transduction; Sepsis; Cancer research; Immunology; Bioinformatics; Cell biology; Medicine; Genetics; Gene","score_opus":0.04569933733843147,"score_gpt":0.32376210688491885,"score_spread":0.2780627695464874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126444826","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.091734834,0.04171489,0.010279461,0.72516847,0.06928688,0.00035051856,0.00023808211,0.0014099914,0.059816908],"genre_scores_gemma":[0.4645615,0.025205143,0.0076665245,0.39098755,0.05410077,0.00053381344,0.00016665563,0.0001227915,0.056655355],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99965775,0.00012885382,0.000026027958,0.000038383536,0.00010101784,0.00004796391],"domain_scores_gemma":[0.9996481,0.00021533355,0.000034599627,0.00003103085,0.000035457513,0.000035518533],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056535087,0.00036223576,0.00041603085,0.00016388703,0.00040986427,0.0007843964,0.0003545697,0.003661015,0.001990057],"category_scores_gemma":[0.0017020799,0.00015284163,0.00043206004,0.000108278335,0.0005651316,0.00041033598,0.0002626239,0.0036676791,0.0014951676],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022882768,0.0006336367,0.0040788553,0.00076221913,0.00014932614,0.052094035,0.0004137104,0.00045103647,0.091456585,0.022618074,0.56814474,0.2569095],"study_design_scores_gemma":[0.00068534916,0.0014560822,0.0034532123,0.00017479145,0.0001453203,0.04979161,0.00024133231,0.0026442404,0.059102535,0.008345055,0.8738945,0.000065886285],"about_ca_topic_score_codex":0.00020654553,"about_ca_topic_score_gemma":0.00050889474,"teacher_disagreement_score":0.003661015,"about_ca_system_score_codex":0.00058269646,"about_ca_system_score_gemma":0.0002635492,"threshold_uncertainty_score":0.006657362},"labels":[],"label_agreement":null},{"id":"W2126683943","doi":"10.1172/jci9896","title":"Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":489,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Heart and Stroke Foundation of Canada; American Heart Association","keywords":"Platelet; Von Willebrand factor; Thrombus; Fibrinogen; Chemistry; Fibrin; Fibronectin; Intravital microscopy; Coagulation; ADAMTS13; Platelet adhesiveness; Immunology; Internal medicine; Pathology; Cell biology; Medicine; Microcirculation; Biology; Biochemistry; Platelet aggregation; Extracellular matrix","score_opus":0.0765742435641735,"score_gpt":0.33933451900716227,"score_spread":0.26276027544298874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126683943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934749,0.0014086249,0.003414495,0.00013988503,0.000022030323,0.000020867301,0.0003620986,0.00012910923,0.0010279679],"genre_scores_gemma":[0.9926109,0.00069869764,0.003544292,0.00007598774,0.000021268397,0.000046938163,0.0005819053,0.00006326939,0.0023568028],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99962723,0.000063239466,0.000034148467,0.000086439584,0.00009452084,0.00009440526],"domain_scores_gemma":[0.9992719,0.00011498981,0.0002810176,0.00006069415,0.00005155921,0.0002198489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026709877,0.00032590682,0.00032064965,0.00091695605,0.00026372643,0.00048453815,0.00021676095,0.00075525587,0.0010455402],"category_scores_gemma":[0.0003375563,0.00040332158,0.00026515772,0.00020204677,0.00034737628,0.00030741698,0.00019421814,0.0011272662,0.00028718627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016558904,0.000038587998,0.0004912747,0.000017143338,0.000008264668,0.000279025,0.00003554917,0.000032677486,0.9978231,0.0002324211,0.000045379402,0.0008311239],"study_design_scores_gemma":[0.00015776884,0.0017626834,0.02940081,0.000025838255,0.0001179775,0.008277438,0.00009781648,0.0023261243,0.95515233,0.00035615894,0.0022966375,0.000028436914],"about_ca_topic_score_codex":0.0005069393,"about_ca_topic_score_gemma":0.0006485599,"teacher_disagreement_score":0.0010455402,"about_ca_system_score_codex":0.00025558402,"about_ca_system_score_gemma":0.00012763923,"threshold_uncertainty_score":0.0034977198},"labels":[],"label_agreement":null},{"id":"W2126743348","doi":"10.1172/jci42127","title":"PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Medical Research Council; Canadian Institutes of Health Research; Université de Lausanne; Islamic Development Bank; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Commission; Diabetes UK; Wellcome Trust; Canadian Diabetes Association; National Institutes of Health; National Science Foundation","keywords":"Internal medicine; Endocrinology; Biology; Insulin; Hyperinsulinemia; Pancreas; Insulin oscillation; Actin cytoskeleton; Pancreatic islets; Adipose tissue; Secretion; Cell biology; Insulin resistance; Islet; Cell; Cytoskeleton; Medicine; Biochemistry","score_opus":0.0576271465624357,"score_gpt":0.33994698657801886,"score_spread":0.2823198400155832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126743348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893551,0.001858677,0.0039364067,0.00042008844,0.000061390725,0.000070103866,0.0015046269,0.00035582366,0.0024376619],"genre_scores_gemma":[0.97602636,0.0030085507,0.0073107784,0.0006125937,0.00003423192,0.00024233187,0.0014786802,0.00029443545,0.010992118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952507,0.000071230774,0.00007822231,0.00014017502,0.00010483485,0.00008050902],"domain_scores_gemma":[0.999597,0.000040203136,0.00014571578,0.000053155007,0.00002250806,0.00014140077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045579424,0.0007737741,0.00038191362,0.0015000212,0.00038572168,0.00079880306,0.00056702516,0.0007407671,0.0023692832],"category_scores_gemma":[0.00022683543,0.0008941282,0.0004865681,0.00052123296,0.0009377299,0.00036819224,0.00043004457,0.0016257447,0.0006872087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011174475,0.00018484602,0.00078113785,0.00005707687,0.000021341986,0.0001576039,0.00003443806,0.00013124081,0.99438727,0.0003168427,0.00008940752,0.0027214044],"study_design_scores_gemma":[0.00046815167,0.001330315,0.014230106,0.00007468414,0.0001223368,0.0012978048,0.00012963271,0.0013702767,0.97499067,0.00060250005,0.005356529,0.000026982872],"about_ca_topic_score_codex":0.00076368224,"about_ca_topic_score_gemma":0.000977728,"teacher_disagreement_score":0.0023692832,"about_ca_system_score_codex":0.00064144237,"about_ca_system_score_gemma":0.0004372202,"threshold_uncertainty_score":0.007926047},"labels":[],"label_agreement":null},{"id":"W2127605198","doi":"10.1172/jci28493","title":"Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Aryl hydrocarbon receptor; Offspring; Pregnancy; Biology; Ovary; Internal medicine; Lactation; Endocrinology; Ovarian follicle; Ovarian reserve; Andrology; Physiology; Medicine; Infertility; Gene; Genetics","score_opus":0.048406181321058346,"score_gpt":0.3314357817904268,"score_spread":0.2830296004693685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127605198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99477744,0.0010602536,0.002106537,0.00011335788,0.000029159812,0.000024806139,0.00032361125,0.00008915391,0.0014755182],"genre_scores_gemma":[0.991411,0.00072545715,0.001009519,0.000070004564,0.000009544462,0.000043709628,0.0003992666,0.000025801202,0.0063056317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998417,0.000019966015,0.00001219459,0.00003802897,0.000045012177,0.00004311701],"domain_scores_gemma":[0.9997918,0.00002711087,0.000070421986,0.000035706646,0.000015678675,0.00005925931],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012236767,0.00022769677,0.00015182297,0.00030184782,0.00012309008,0.00022833659,0.00019128206,0.00020882097,0.0015507576],"category_scores_gemma":[0.0001065682,0.00013780895,0.00020810006,0.00009634336,0.00020138592,0.0001475492,0.000227493,0.0005746991,0.00032398428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009830742,0.0000407566,0.00035925323,0.000013364957,0.0000027119252,0.00004634591,0.000014219164,0.00001872771,0.99830425,0.00007941561,0.000020590798,0.0010020927],"study_design_scores_gemma":[0.000019116367,0.0007824114,0.012521634,0.0000065349172,0.000014986604,0.00029068268,0.000046761084,0.00044678568,0.983194,0.000057982277,0.0026150243,0.0000040525483],"about_ca_topic_score_codex":0.00046383197,"about_ca_topic_score_gemma":0.0009765881,"teacher_disagreement_score":0.0015507576,"about_ca_system_score_codex":0.00019624644,"about_ca_system_score_gemma":0.00016989687,"threshold_uncertainty_score":0.0051878095},"labels":[],"label_agreement":null},{"id":"W2127625135","doi":"10.1172/jci21689","title":"A role for proteinase-activated receptor–1 in inflammatory bowel diseases","year":2004,"lang":"en","type":"retraction","venue":"Journal of Clinical Investigation","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":97,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation; University of Calgary","keywords":"Inflammation; Colitis; Inflammatory bowel disease; Pathogenesis; Immunology; Thrombin; Receptor; Proinflammatory cytokine; Gastrointestinal tract; Medicine; Internal medicine; Disease; Platelet","score_opus":0.08037441316340546,"score_gpt":0.38139968582789585,"score_spread":0.3010252726644904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127625135","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016200526,0.36986113,0.0038041824,0.13671687,0.4338317,0.00015041664,0.00031803624,0.00020078523,0.03891632],"genre_scores_gemma":[0.074756876,0.4207647,0.0042839088,0.020195995,0.3717397,0.00018512143,0.00045551138,0.00008377454,0.10753431],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99972326,0.000057575286,0.00005665132,0.000044395834,0.00008097788,0.000037256945],"domain_scores_gemma":[0.99912614,0.00027950612,0.00009341413,0.000034194225,0.00033643667,0.00013029207],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009458845,0.0010931294,0.0005919086,0.0008137015,0.00041802964,0.0007124436,0.00056929793,0.0014869848,0.004051757],"category_scores_gemma":[0.0026014848,0.00022327325,0.0002961722,0.00046008368,0.00087106344,0.0009457091,0.00039732674,0.0029722278,0.0023847215],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010777791,0.00008306094,0.0015396068,0.0046949494,0.0000907439,0.00967935,0.00029047506,0.00038583484,0.016140603,0.017828649,0.6461975,0.30199143],"study_design_scores_gemma":[0.00009379249,0.00017857568,0.007243021,0.00057484023,0.00007896268,0.0073197833,0.00006479627,0.00029900833,0.0026369358,0.0021864334,0.97930396,0.000019997457],"about_ca_topic_score_codex":0.0008482719,"about_ca_topic_score_gemma":0.0011136285,"teacher_disagreement_score":0.99851304,"about_ca_system_score_codex":0.0008453127,"about_ca_system_score_gemma":0.0007507316,"threshold_uncertainty_score":0.013554454},"labels":[],"label_agreement":null},{"id":"W2128006949","doi":"10.1172/jci23915","title":"Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":447,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; Killam Trusts; National Institutes of Health; Michael Smith Health Research BC; Wake Forest University","keywords":"ABCA1; Tangier disease; Catabolism; ATP Binding Cassette Transporter 1; Endocrinology; Internal medicine; Cholesterol; Apolipoprotein B; Kidney; Reverse cholesterol transport; Chemistry; Biology; Biochemistry; Lipoprotein; Metabolism; Medicine; Transporter","score_opus":0.05384288293225244,"score_gpt":0.3573616518087649,"score_spread":0.30351876887651247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128006949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982529,0.00024653846,0.0008052188,0.000074624135,0.00001093056,0.000011704613,0.00010576925,0.00012017491,0.00037209372],"genre_scores_gemma":[0.9984388,0.00016979543,0.00045884657,0.00007375587,0.000014737956,0.00001660944,0.00014672877,0.000024020914,0.00065667555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985206,0.000027909247,0.000019125247,0.000039936807,0.000030664974,0.00003040548],"domain_scores_gemma":[0.9998301,0.000029152427,0.00005819983,0.0000141021,0.0000090242165,0.00005933493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012235774,0.0009426694,0.00047701874,0.00047352354,0.00023604037,0.00025547098,0.00017332486,0.0004590052,0.0014967915],"category_scores_gemma":[0.00020432759,0.00027977853,0.00028801218,0.00023086568,0.0004228576,0.00013988475,0.00022749777,0.00062140526,0.00042020134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00087940856,0.00017188722,0.006307604,0.000063210566,0.00006286764,0.0061521204,0.000063550564,0.00017210406,0.9813774,0.0002014118,0.00023063808,0.004317747],"study_design_scores_gemma":[0.0009708956,0.004316522,0.24456498,0.00004065073,0.0006078068,0.08711858,0.00023247786,0.004990919,0.65028065,0.00078324624,0.006015816,0.00007741089],"about_ca_topic_score_codex":0.0006752657,"about_ca_topic_score_gemma":0.0008070601,"teacher_disagreement_score":0.0014967915,"about_ca_system_score_codex":0.0003259963,"about_ca_system_score_gemma":0.00016425342,"threshold_uncertainty_score":0.005007267},"labels":[],"label_agreement":null},{"id":"W2128242002","doi":"10.1172/jci34672","title":"VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute on Alcohol Abuse and Alcoholism; University of Toronto; U.S. Army Medical Research Acquisition Activity; National Institutes of Health; King's College London","keywords":"Exocytosis; Cell biology; Secretion; Zymogen; Epithelial polarity; Acinar cell; Chemistry; Syntaxin; Biology; Internal medicine; Endocrinology; Biochemistry; Pancreas; Medicine; Cell; Enzyme","score_opus":0.16927549426415167,"score_gpt":0.3563864009225822,"score_spread":0.18711090665843055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128242002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98237395,0.0024144324,0.009012533,0.00085357233,0.00023919185,0.00024696003,0.002255835,0.0006889018,0.0019146894],"genre_scores_gemma":[0.9766019,0.002747523,0.0071401144,0.00032518513,0.000071185605,0.00076488766,0.0022278551,0.00017061483,0.009950802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943906,0.00008514513,0.00009002627,0.00014843982,0.00013295315,0.00010432906],"domain_scores_gemma":[0.9995999,0.000024779987,0.0001491113,0.00004002162,0.00002983694,0.00015647087],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040434636,0.0012870339,0.00071777013,0.0015770264,0.0005952499,0.0005778904,0.0007013381,0.0016214116,0.0037643015],"category_scores_gemma":[0.00023167141,0.0005600586,0.00080626534,0.0005289158,0.0007932172,0.0009921096,0.00061993586,0.0023633365,0.0011730789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009392178,0.00032955705,0.00054416,0.0000870331,0.000019378067,0.0004146004,0.000043120275,0.00011372375,0.995284,0.00043614415,0.00019922057,0.0015898471],"study_design_scores_gemma":[0.00049100496,0.0037721465,0.012448642,0.00010469055,0.00014757653,0.00468514,0.0002510165,0.0040486967,0.9633002,0.00069685327,0.010009937,0.00004405752],"about_ca_topic_score_codex":0.0007201706,"about_ca_topic_score_gemma":0.0008925318,"teacher_disagreement_score":0.0037643015,"about_ca_system_score_codex":0.0007630643,"about_ca_system_score_gemma":0.0003778963,"threshold_uncertainty_score":0.012592852},"labels":[],"label_agreement":null},{"id":"W2128496826","doi":"10.1172/jci46088","title":"Growing a tumor stroma: a role for granulin and the bone marrow","year":2011,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital; McGill University Health Centre","funders":"Astellas Foundation for Research on Metabolic Disorders; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; Astellas Pharma; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Uehara Memorial Foundation; Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care; Suzuken Memorial Foundation","keywords":"Stromal cell; Bone marrow; Stroma; Cancer research; Haematopoiesis; Carcinogenesis; Tumor progression; Biology; Progenitor cell; Stem cell; Cancer; Immunology; Pathology; Medicine; Cell biology; Genetics; Immunohistochemistry","score_opus":0.06277724694104093,"score_gpt":0.3767053342269013,"score_spread":0.31392808728586036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128496826","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13356915,0.13367727,0.0047898414,0.6691688,0.017892774,0.00015676,0.00013468126,0.00033252352,0.040278282],"genre_scores_gemma":[0.7550034,0.042106796,0.006123052,0.12581366,0.055200424,0.00020677791,0.000076573306,0.00005306309,0.015416233],"study_design_codex":"case_report","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997042,0.00011991906,0.000031644777,0.00003748897,0.00006531817,0.000041320698],"domain_scores_gemma":[0.9990707,0.00059894,0.00010057144,0.00007761663,0.00006229657,0.00008993492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005104362,0.00038467473,0.0005260845,0.00037334423,0.00049345725,0.0010671228,0.0005812528,0.0053101773,0.0024850895],"category_scores_gemma":[0.0015877587,0.00020461359,0.0002771198,0.00017605099,0.0013207631,0.0012532097,0.00051208824,0.003301112,0.00096560456],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020351764,0.00037256526,0.012757818,0.0015474694,0.000117698204,0.4981528,0.0008838216,0.00067428703,0.050726544,0.052726172,0.16054052,0.21946523],"study_design_scores_gemma":[0.00086614344,0.00065951847,0.012650546,0.00067745463,0.00013703316,0.4645923,0.0007966662,0.004355397,0.014600554,0.036944546,0.46365413,0.00006576414],"about_ca_topic_score_codex":0.00024702505,"about_ca_topic_score_gemma":0.00045252283,"teacher_disagreement_score":0.0053101773,"about_ca_system_score_codex":0.0009238647,"about_ca_system_score_gemma":0.0002922899,"threshold_uncertainty_score":0.008313477},"labels":[],"label_agreement":null},{"id":"W2128575549","doi":"10.1172/jci65093","title":"Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Protein phosphatase 2; Apoptosis; Dephosphorylation; Cancer research; Cell culture; Leukemia; Chemistry; Pharmacology; Biology; Phosphatase; Phosphorylation; Biochemistry; Immunology","score_opus":0.02940821537407966,"score_gpt":0.29744031516085023,"score_spread":0.26803209978677056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128575549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99475914,0.0016583357,0.0016477245,0.00010395904,0.000021909882,0.000058574307,0.00049303274,0.00009225804,0.0011649652],"genre_scores_gemma":[0.9946207,0.0017519742,0.0016132456,0.0000825504,0.0000102450285,0.00006796203,0.0007302688,0.000015867297,0.0011073197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998832,0.000024451083,0.000014050185,0.000020896756,0.00003099848,0.000026352967],"domain_scores_gemma":[0.9999429,0.000013737554,0.000017148508,0.000008208436,0.000006806266,0.000011142105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012159706,0.00036330268,0.0002548618,0.00025639337,0.00013285647,0.00018372342,0.00010724828,0.00014750488,0.00090400607],"category_scores_gemma":[0.00010488558,0.00013383769,0.00026774994,0.0002389084,0.00013991517,0.00011007866,0.00015824357,0.0004016872,0.00019415983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016360139,0.00003222762,0.00025883858,0.000036701244,0.00001055817,0.00006440096,0.000010433383,0.00011420107,0.99793184,0.000035727062,0.00006268143,0.0012788846],"study_design_scores_gemma":[0.000044804085,0.0007501086,0.0062773973,0.0000038248495,0.000025479467,0.00038963978,0.000023546121,0.0009078661,0.9899817,0.00003692488,0.0015555077,0.0000030739716],"about_ca_topic_score_codex":0.0009369217,"about_ca_topic_score_gemma":0.002033577,"teacher_disagreement_score":0.0009369217,"about_ca_system_score_codex":0.00031641428,"about_ca_system_score_gemma":0.00018999692,"threshold_uncertainty_score":0.0030241609},"labels":[],"label_agreement":null},{"id":"W2128877497","doi":"10.1172/jci41229","title":"Making the blastocyst: lessons from the mouse","year":2010,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":399,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Epiblast; Blastocyst; Biology; Embryonic stem cell; Embryo; Inner cell mass; Embryogenesis; Endoderm; Cell biology; Genetics; Andrology; Gastrulation; Gene; Medicine","score_opus":0.25901900695470853,"score_gpt":0.4856474473016056,"score_spread":0.22662844034689705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128877497","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025925992,0.9961494,0.00047608835,0.0006369615,0.00029796924,0.0000044707917,0.000015909001,0.000015258925,0.0021446382],"genre_scores_gemma":[0.0012274601,0.9960907,0.0007450181,0.000510287,0.00018190024,0.000008489294,0.000020968508,0.0000047954723,0.0012104051],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998425,0.000024788247,0.000024367639,0.00002775366,0.00007003622,0.000010519804],"domain_scores_gemma":[0.9997898,0.0000917203,0.000021488431,0.000011997754,0.000048084934,0.00003705037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010760024,0.00079959125,0.0010139766,0.0015084629,0.00026427818,0.0009905834,0.0010643121,0.0013741512,0.002083746],"category_scores_gemma":[0.0008141979,0.00024784106,0.00024446996,0.0011262767,0.0011276106,0.0018429302,0.00066341815,0.0017799438,0.002354943],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008910307,0.00005769932,0.00021960227,0.005658499,0.00004137908,0.00061265024,0.00018309284,0.00043503192,0.0052359323,0.01765196,0.03440771,0.9354074],"study_design_scores_gemma":[0.000021908001,0.00006775598,0.0004465798,0.0013136312,0.000032182717,0.0012478685,0.00006867644,0.00006649731,0.0011034256,0.004963678,0.9906551,0.000012557344],"about_ca_topic_score_codex":0.0011251476,"about_ca_topic_score_gemma":0.0018424244,"teacher_disagreement_score":0.002083746,"about_ca_system_score_codex":0.0006136596,"about_ca_system_score_gemma":0.00059646234,"threshold_uncertainty_score":0.006970823},"labels":[],"label_agreement":null},{"id":"W2128937433","doi":"10.1172/jci23203","title":"Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":365,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Fondation pour la Recherche Médicale; National Cancer Institute; National Institutes of Health; Bristol-Myers Squibb; University of Alberta; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Survivin; Apoptosis; Cancer research; Vascular smooth muscle; Inhibitor of apoptosis; Biology; Downregulation and upregulation; Mitochondrion; Chemistry; Endocrinology; Programmed cell death; Cell biology; Gene; Biochemistry","score_opus":0.09832385847673017,"score_gpt":0.3540108137765159,"score_spread":0.2556869552997857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128937433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909208,0.0034503457,0.0038994038,0.00017815235,0.000098986086,0.000046243127,0.0000694532,0.00011759598,0.0012190775],"genre_scores_gemma":[0.99544513,0.0019497126,0.0013280943,0.000046348327,0.000027905045,0.000023081162,0.00011893244,0.000013550223,0.0010473739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983656,0.000028430131,0.000018419882,0.000025675547,0.00003904144,0.00005173906],"domain_scores_gemma":[0.9998797,0.00002547545,0.000037355858,0.000015235273,0.00001721938,0.000025112204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019055099,0.0002999722,0.00046271735,0.00029093257,0.00012430048,0.0003557446,0.00020566925,0.0003030696,0.0005445402],"category_scores_gemma":[0.00022595494,0.0001128445,0.00019395501,0.0001757942,0.0003148507,0.00020588959,0.00012881093,0.0006553393,0.00018603179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032797837,0.00017741481,0.00027352286,0.00007000959,0.000019417263,0.00013694016,0.000028649603,0.00021744675,0.98887396,0.00036611734,0.00013550892,0.009373011],"study_design_scores_gemma":[0.00036644356,0.0066350084,0.0036427593,0.00002136575,0.00014112817,0.0010860994,0.00005673908,0.002986752,0.9785039,0.00018117706,0.006368812,0.000009884544],"about_ca_topic_score_codex":0.0004487545,"about_ca_topic_score_gemma":0.0007182649,"teacher_disagreement_score":0.0005445402,"about_ca_system_score_codex":0.00023009918,"about_ca_system_score_gemma":0.00020970347,"threshold_uncertainty_score":0.0018216968},"labels":[],"label_agreement":null},{"id":"W2129163454","doi":"10.1172/jci37409","title":"Adenosine signaling contributes to ethanol-induced fatty liver in mice","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":158,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; School of Medicine, New York University; York University; Vilcek Foundation; Arthritis Foundation","keywords":"Adenosine; Adenosine receptor; Fatty liver; Steatosis; Endocrinology; Internal medicine; Purinergic signalling; Adenosine A1 receptor; Alcoholic fatty liver; Fatty acid metabolism; Biology; Adenosine A3 receptor; Fatty acid; Receptor; Biochemistry; Chemistry; Medicine; Agonist","score_opus":0.060226448269842615,"score_gpt":0.3559226718015311,"score_spread":0.29569622353168845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129163454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95334405,0.011219358,0.014093111,0.0030284727,0.0004030363,0.0003804708,0.0042263893,0.0010204961,0.012284636],"genre_scores_gemma":[0.9623739,0.007916667,0.008089075,0.0010872926,0.00012919857,0.0008663239,0.0026544598,0.00022022569,0.016662814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951136,0.00009419036,0.00005589249,0.00010628191,0.00011177118,0.000120560944],"domain_scores_gemma":[0.99962425,0.000031441457,0.00013997343,0.00003383173,0.000028195369,0.00014219817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004185259,0.0008042005,0.0005549473,0.0012407345,0.00047420993,0.00074413995,0.0004998382,0.0011956494,0.0047050845],"category_scores_gemma":[0.00021981187,0.0007492708,0.00070385134,0.00051152235,0.00064836215,0.0005731786,0.0005171509,0.001976914,0.0017824263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015565791,0.00027986258,0.00058924395,0.00019108116,0.000028587334,0.00036771473,0.00006003239,0.00022226808,0.9910629,0.00083713554,0.00042822666,0.004376391],"study_design_scores_gemma":[0.0008468004,0.002829716,0.024183553,0.00021093912,0.0002652788,0.0022647844,0.0003246212,0.006011051,0.93538547,0.0015276496,0.026086884,0.00006331813],"about_ca_topic_score_codex":0.00082952605,"about_ca_topic_score_gemma":0.0014938704,"teacher_disagreement_score":0.0047050845,"about_ca_system_score_codex":0.00076929916,"about_ca_system_score_gemma":0.0005094439,"threshold_uncertainty_score":0.015740037},"labels":[],"label_agreement":null},{"id":"W2129313145","doi":"10.1172/jci11918","title":"Hostile takeovers: viral appropriation of the NF-kB pathway","year":2001,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":606,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital","funders":"National Cancer Institute; Fonds de Recherche du Québec - Santé; McGill University; Canadian Institutes of Health Research; Canadian Foundation for AIDS Research","keywords":"Appropriation; Virology; Cell biology; Biology; Philosophy; Linguistics","score_opus":0.12384618022445684,"score_gpt":0.38931465700665524,"score_spread":0.2654684767821984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129313145","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0061283982,0.98394656,0.0016532487,0.0005479811,0.00057901314,0.000016120552,0.00009081585,0.00004371093,0.0069941864],"genre_scores_gemma":[0.049723018,0.94123393,0.0015514519,0.0009749074,0.0009033685,0.000030270468,0.00020761252,0.000020214502,0.00535523],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99982893,0.000023758343,0.000013550245,0.00004483321,0.000056314595,0.000032569642],"domain_scores_gemma":[0.9999105,0.000024526815,0.000020482525,0.0000038591597,0.000024370782,0.000016321343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026003763,0.0004509713,0.00056823075,0.0004665033,0.00018913945,0.00095567317,0.00037693838,0.00049149717,0.0018162169],"category_scores_gemma":[0.0002150673,0.00008886017,0.0002418101,0.0003046313,0.00028387472,0.0009232414,0.0003275484,0.00089025433,0.0006390267],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043548192,0.00010593408,0.0012529368,0.014100929,0.00015897691,0.0019275224,0.00057526276,0.00074681756,0.22228447,0.019621626,0.013908929,0.72488123],"study_design_scores_gemma":[0.000029179708,0.0005879492,0.0035947217,0.0015040558,0.00015424895,0.004326382,0.00024213549,0.00029518755,0.051620584,0.008199901,0.9293975,0.00004816227],"about_ca_topic_score_codex":0.00030401678,"about_ca_topic_score_gemma":0.0005175686,"teacher_disagreement_score":0.0018162169,"about_ca_system_score_codex":0.00059351296,"about_ca_system_score_gemma":0.00034895225,"threshold_uncertainty_score":0.006075859},"labels":[],"label_agreement":null},{"id":"W2129431737","doi":"10.1172/jci17912","title":"Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":458,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; American Heart Association","keywords":"Arginase; Pathogenesis; Asthma; Biology; Immunology; Activator (genetics); Gene expression; Arginine; Gene; Biochemistry; Amino acid","score_opus":0.03651366016870555,"score_gpt":0.3512952479161583,"score_spread":0.31478158774745274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129431737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9736158,0.002492412,0.019786267,0.00041868238,0.000058536414,0.00014849404,0.0016771854,0.00016323103,0.0016392375],"genre_scores_gemma":[0.9590044,0.0029473703,0.03075341,0.00027774644,0.000052631243,0.00039316656,0.0034510244,0.000035905294,0.0030844156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954164,0.00010920031,0.00003603861,0.00009406942,0.00012272125,0.00009639835],"domain_scores_gemma":[0.9998275,0.000058377504,0.00004131693,0.000026405813,0.0000177041,0.00002854806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043674282,0.00024167342,0.00036931084,0.0005703228,0.0002504918,0.00040873728,0.00020323561,0.00037664146,0.0008768481],"category_scores_gemma":[0.00027218938,0.00019462784,0.00034678067,0.00038361564,0.0002597049,0.00017161784,0.00021468007,0.00068470655,0.00036971367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020271508,0.000037557103,0.001282075,0.000031157022,0.000007544624,0.000028819713,0.000017009517,0.00008252841,0.99541926,0.000096263255,0.000043143038,0.0027519101],"study_design_scores_gemma":[0.000060453218,0.0012424345,0.08835867,0.000030352709,0.000117234646,0.0006642175,0.00017156995,0.004793293,0.89503384,0.00077091047,0.008730222,0.000026716525],"about_ca_topic_score_codex":0.00033701514,"about_ca_topic_score_gemma":0.0007399304,"teacher_disagreement_score":0.0008768481,"about_ca_system_score_codex":0.00025982675,"about_ca_system_score_gemma":0.00024154237,"threshold_uncertainty_score":0.0029333234},"labels":[],"label_agreement":null},{"id":"W2129997470","doi":"10.1172/jci59492","title":"T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":217,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Health and Medical Research Council","keywords":"Protein tyrosine phosphatase; Autoimmunity; T cell; Biology; CD8; Immunology; Proinflammatory cytokine; T-cell receptor; Autoimmune disease; Inflammation; Regulatory T cell; Signal transduction; Cell biology; IL-2 receptor; Antigen; Antibody; Immune system","score_opus":0.044221680769247707,"score_gpt":0.30684310555942107,"score_spread":0.26262142479017336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129997470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9796051,0.0034195776,0.010042951,0.0007762974,0.00016706635,0.00016845857,0.00082020723,0.0007180458,0.00428221],"genre_scores_gemma":[0.9813157,0.001931739,0.0072675827,0.00028814425,0.00007701589,0.00026382355,0.00080915465,0.00015050948,0.007896417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934834,0.00013084621,0.00006250923,0.0001508762,0.00016069267,0.00014671561],"domain_scores_gemma":[0.99955505,0.000068060435,0.00013524867,0.00006281333,0.00003562014,0.00014317497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004395866,0.0008069159,0.0004182148,0.00091217336,0.00032442628,0.00057569874,0.0005266254,0.000906491,0.0022777922],"category_scores_gemma":[0.0003240028,0.0004287012,0.00041533954,0.00032228345,0.0007268216,0.00048583033,0.0003320685,0.0019654413,0.00071906066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004246699,0.00022853939,0.00025824766,0.000054546173,0.00001790648,0.000129565,0.000028737206,0.00018303424,0.99500054,0.0005496586,0.0002035624,0.0029209414],"study_design_scores_gemma":[0.0003340434,0.0016675084,0.0024310001,0.000031406114,0.00005805618,0.000993578,0.000034537374,0.0033217804,0.98313934,0.00045689204,0.0075213695,0.000010521036],"about_ca_topic_score_codex":0.0006431034,"about_ca_topic_score_gemma":0.001000319,"teacher_disagreement_score":0.0022777922,"about_ca_system_score_codex":0.00052576244,"about_ca_system_score_gemma":0.00039684557,"threshold_uncertainty_score":0.007619977},"labels":[],"label_agreement":null},{"id":"W2130324831","doi":"10.1172/jci18648","title":"A role for surface lymphotoxin in experimental autoimmune encephalomyelitis independent of LIGHT","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs","funders":"Biogen","keywords":"Lymphotoxin; Experimental autoimmune encephalomyelitis; Pertussis toxin; Immunology; Multiple sclerosis; Biology; T cell; Receptor; Priming (agriculture); Pathogenesis; Bordetella pertussis; Myelin oligodendrocyte glycoprotein; Autoimmune disease; Immune system; Cell biology; Signal transduction; Antibody; G protein; Genetics","score_opus":0.034722802521450595,"score_gpt":0.313838066204831,"score_spread":0.2791152636833804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130324831","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803656,0.009382525,0.0053092833,0.00035924764,0.000055808683,0.000041597435,0.000100069716,0.00020916676,0.0041766083],"genre_scores_gemma":[0.9934447,0.002332165,0.001958196,0.00009483501,0.000022552136,0.000031949377,0.00011335823,0.000020254121,0.0019821236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997929,0.000057360452,0.000024720446,0.00003406743,0.00004389217,0.000047189045],"domain_scores_gemma":[0.99959344,0.000103361,0.0001154235,0.00006611787,0.000040771192,0.000080883634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004743661,0.0005749593,0.00025734483,0.00035378413,0.00023499574,0.0004374234,0.00020777351,0.00044595497,0.0011060971],"category_scores_gemma":[0.00025388369,0.000112266214,0.00022396365,0.00010854837,0.0005813562,0.00042123668,0.0002850145,0.00068656163,0.0003544999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037144343,0.000041082778,0.00051058666,0.00007131826,0.0000040032423,0.00014389999,0.000018901981,0.000023207942,0.99506724,0.00062728085,0.000023393957,0.0030976832],"study_design_scores_gemma":[0.00014513897,0.0016636464,0.011976072,0.00007794167,0.000066726454,0.0015653541,0.00006613752,0.0007823699,0.9791586,0.00106709,0.0034232237,0.000007739736],"about_ca_topic_score_codex":0.00022039234,"about_ca_topic_score_gemma":0.00032374775,"teacher_disagreement_score":0.0011060971,"about_ca_system_score_codex":0.00032015814,"about_ca_system_score_gemma":0.0002765882,"threshold_uncertainty_score":0.0037001967},"labels":[],"label_agreement":null},{"id":"W2130827011","doi":"10.1172/jci16510","title":"Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":406,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"TLR4; Bone marrow; Intravital microscopy; Endothelium; Immunology; Lipopolysaccharide; Inflammation; Pulmonary sequestration; Microcirculation; Biology; Medicine; Pathology; Lung; Internal medicine; Endocrinology","score_opus":0.04664398978921872,"score_gpt":0.32455398685784503,"score_spread":0.2779099970686263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130827011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97519284,0.01148872,0.010239761,0.0005677504,0.000084723135,0.000086837565,0.00034575397,0.00019078638,0.0018026817],"genre_scores_gemma":[0.98773915,0.0027644264,0.004739619,0.00014112107,0.000048189813,0.00010997671,0.00039095257,0.000018828941,0.004047747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996822,0.0001082323,0.000029637102,0.000049378097,0.000069398004,0.00006121864],"domain_scores_gemma":[0.9997882,0.000023155791,0.00010128638,0.000018654955,0.000024902194,0.000043797383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029705733,0.00047404697,0.00033576376,0.00023911236,0.00016447048,0.0002965754,0.00029702872,0.0005633069,0.0015502652],"category_scores_gemma":[0.00020789717,0.00024583243,0.0003284214,0.000093995106,0.0002672539,0.00040133315,0.0005205366,0.00073790835,0.0005966975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003852176,0.000029226921,0.0005510804,0.000076317294,0.00000625274,0.00020948713,0.000009797488,0.000065339605,0.9966144,0.00012422193,0.00005143612,0.0018771698],"study_design_scores_gemma":[0.00006684327,0.0010238534,0.023382427,0.00003178983,0.000063456595,0.0014756445,0.00007744805,0.0019575427,0.9672675,0.00025763165,0.004381505,0.0000143489],"about_ca_topic_score_codex":0.00020069201,"about_ca_topic_score_gemma":0.00016595663,"teacher_disagreement_score":0.0015502652,"about_ca_system_score_codex":0.00027881298,"about_ca_system_score_gemma":0.00023361626,"threshold_uncertainty_score":0.0051861405},"labels":[],"label_agreement":null},{"id":"W2131276542","doi":"10.1172/jci15316","title":"Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Nitric oxide; Chemistry; Biophysics; Stimulation; Protein subunit; Carbon monoxide; Agonist; Pharmacology; Nitric oxide synthase; Cell biology; Biochemistry; Internal medicine; Medicine; Biology; Receptor; Gene","score_opus":0.09247713089352295,"score_gpt":0.3271748391372642,"score_spread":0.23469770824374125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131276542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94738007,0.036404982,0.009625536,0.0011678555,0.00041387073,0.00020984373,0.0002870511,0.00012578699,0.0043849684],"genre_scores_gemma":[0.9890469,0.005762735,0.0030370476,0.00031563887,0.00012495855,0.00021026946,0.00012440208,0.0000119023425,0.0013661482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994456,0.00011858841,0.00005686007,0.0001097877,0.00010644734,0.0001628232],"domain_scores_gemma":[0.9995096,0.00014337534,0.000068316476,0.00005677333,0.00008685826,0.00013513729],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005903741,0.00054454507,0.0007912155,0.00033130927,0.00036181384,0.0005308064,0.00047767238,0.0010404281,0.0008682441],"category_scores_gemma":[0.0004341744,0.00029689312,0.00080182985,0.00014247233,0.00070006866,0.0011446925,0.00052154134,0.00084144686,0.00021361241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060079957,0.00006287472,0.000545071,0.00033264942,0.000025074747,0.00031237784,0.000073444644,0.00012598453,0.99464864,0.0011881416,0.00006271829,0.0020223027],"study_design_scores_gemma":[0.0003729159,0.0017417682,0.086097345,0.00012715248,0.00019841391,0.0022564512,0.0005571506,0.0064333025,0.89299303,0.0033711935,0.0057652984,0.000085962674],"about_ca_topic_score_codex":0.0002794882,"about_ca_topic_score_gemma":0.0004120411,"teacher_disagreement_score":0.0010404281,"about_ca_system_score_codex":0.00040904677,"about_ca_system_score_gemma":0.0003476254,"threshold_uncertainty_score":0.0031222105},"labels":[],"label_agreement":null},{"id":"W2131374289","doi":"10.1172/jci15598","title":"Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice","year":2003,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":331,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada)","funders":"American Heart Association; National Institutes of Health; National Science Foundation","keywords":"RGS2; Heterotrimeric G protein; G protein; G protein-coupled receptor; Receptor; Regulator of G protein signaling; Endocrinology; Internal medicine; Signal transduction; Agonist; Gq alpha subunit; Biology; Blood pressure; Cell biology; GTPase-activating protein; Medicine","score_opus":0.13009429383575546,"score_gpt":0.3557628744495192,"score_spread":0.22566858061376374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131374289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5910751,0.0111493645,0.0061748726,0.33162078,0.0109765725,0.00030917765,0.0008488888,0.0016335637,0.04621162],"genre_scores_gemma":[0.8839612,0.0060938452,0.0035465686,0.062056087,0.013449694,0.00013798279,0.0003475226,0.00020363461,0.030203355],"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996997,0.00009237231,0.00002901273,0.000055929046,0.00008005333,0.00004294691],"domain_scores_gemma":[0.99928766,0.0003872595,0.00009169478,0.00004635097,0.00006285536,0.0001241266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004585646,0.0007756508,0.0007353107,0.00038585276,0.0005429931,0.0007066352,0.0003407401,0.0043079024,0.001960358],"category_scores_gemma":[0.0016282402,0.00034140405,0.00035967765,0.00017317718,0.00076344545,0.0005222201,0.00021359063,0.002429967,0.0010149538],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041706455,0.00047031668,0.021356432,0.0005649226,0.00023258009,0.60529983,0.0010132707,0.0007600523,0.13595858,0.007642644,0.15127207,0.07125863],"study_design_scores_gemma":[0.001477908,0.0020923195,0.060465522,0.00034038466,0.00035733206,0.6777003,0.00033103867,0.008063323,0.044856045,0.0117842965,0.1923687,0.00016288902],"about_ca_topic_score_codex":0.00040413422,"about_ca_topic_score_gemma":0.0005888742,"teacher_disagreement_score":0.0043079024,"about_ca_system_score_codex":0.0006901135,"about_ca_system_score_gemma":0.000214686,"threshold_uncertainty_score":0.0065580606},"labels":[],"label_agreement":null},{"id":"W2131549241","doi":"10.1172/jci18114","title":"The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":177,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; McMaster University; University Health Network; University of Toronto; Hamilton Health Sciences; St. Michael's Hospital; Canada Research Chairs","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Heart and Stroke Foundation of Canada","keywords":"Prothrombinase; Viral hepatitis; Fibrin; Virology; Immunology; Mouse hepatitis virus; Hepatitis; Medicine; Biology; Thrombin; Pathology; Platelet","score_opus":0.07351546400952162,"score_gpt":0.3931727325082992,"score_spread":0.31965726849877757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131549241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997785,0.00093356555,0.00069171767,0.000042688993,0.0000040437685,0.000012488622,0.000051685565,0.000020244837,0.0004585907],"genre_scores_gemma":[0.99877495,0.00035739658,0.00034245555,0.0000329371,0.000009776066,0.000013034574,0.00008840531,0.000004684295,0.00037638246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999032,0.00004131182,0.000009594533,0.00001385944,0.000014579468,0.000017547965],"domain_scores_gemma":[0.9999044,0.000014101413,0.000034232253,0.000011491448,0.000007556153,0.00002833432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021215725,0.00030114676,0.00014852545,0.00039370486,0.00010451139,0.00019263318,0.00006954717,0.0002562455,0.00077090744],"category_scores_gemma":[0.0001899779,0.00009824937,0.00012635608,0.000116500116,0.00030772225,0.00010059421,0.00015400126,0.00022787463,0.00016044237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010733193,0.00006406809,0.005284461,0.0000598672,0.000010036426,0.00075251446,0.00005416319,0.000072090595,0.9898318,0.00013175589,0.000048528196,0.0026173843],"study_design_scores_gemma":[0.00023496537,0.0024653133,0.31491637,0.000047431186,0.00011225296,0.014737539,0.00021826712,0.0024879638,0.65967727,0.00053573376,0.0045457403,0.000021189953],"about_ca_topic_score_codex":0.00021130049,"about_ca_topic_score_gemma":0.00018801782,"teacher_disagreement_score":0.00077090744,"about_ca_system_score_codex":0.00014650194,"about_ca_system_score_gemma":0.00007390732,"threshold_uncertainty_score":0.0025789142},"labels":[],"label_agreement":null},{"id":"W2131809876","doi":"10.1172/jci75199","title":"Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":204,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Institute on Aging; National Health and Medical Research Council; National Institutes of Health; Fondation pour la Recherche Médicale; Ministero della Salute; Murdoch Children's Research Institute; University of Pennsylvania; Schlumberger Foundation; Muscular Dystrophy Association; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Broad Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Medical Research Council; Ospedale Pediatrico Bambino Gesù; Children’s Hospital of Wisconsin Research Institute; Great Ormond Street Hospital for Children","keywords":"Nemaline myopathy; Nebulin; Skeletal muscle; Congenital myopathy; Actin; Biology; Sanger sequencing; Zebrafish; Myopathy; Phenotype; Gene; Gene knockdown; Collagen VI; Mutation; Genetics; Molecular biology; Cell biology; Myocyte; Sarcomere; Pathology; Muscle biopsy; Anatomy; Medicine; Titin; Biopsy","score_opus":0.054864190663771004,"score_gpt":0.34971987652207476,"score_spread":0.29485568585830374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131809876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99775225,0.00021506911,0.0011048348,0.00005770582,0.00001776989,0.000019294497,0.00021954365,0.000041915268,0.00057160016],"genre_scores_gemma":[0.9979303,0.00014571316,0.0010345201,0.00007142857,0.0000064109754,0.00001458382,0.00023181998,0.000021235935,0.0005440138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998141,0.000025561169,0.000025449934,0.000059839673,0.000047127214,0.000027906457],"domain_scores_gemma":[0.999816,0.00004834295,0.0000606294,0.00001086304,0.00001250865,0.00005163296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020509429,0.0005779945,0.00030313,0.00044482917,0.00035298197,0.00015208479,0.00018305196,0.0005060761,0.0014138469],"category_scores_gemma":[0.00036481084,0.00016558582,0.0003390418,0.00022544149,0.0004519866,0.00013959015,0.00043979473,0.00036770102,0.00023127106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049799524,0.00008663397,0.023048477,0.00010085711,0.00008318019,0.04698989,0.00017564399,0.00028466553,0.9226398,0.00032318922,0.0002679763,0.005501696],"study_design_scores_gemma":[0.00016108043,0.00069232937,0.4770934,0.00008203718,0.00023839725,0.18841055,0.00037358465,0.003732126,0.32306266,0.000691431,0.005411117,0.000051349845],"about_ca_topic_score_codex":0.00045299457,"about_ca_topic_score_gemma":0.0010944689,"teacher_disagreement_score":0.0014138469,"about_ca_system_score_codex":0.00022512788,"about_ca_system_score_gemma":0.00019234227,"threshold_uncertainty_score":0.0047298074},"labels":[],"label_agreement":null},{"id":"W2131897198","doi":"10.1172/jci69073","title":"Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":195,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Vanderbilt University; Amgen; American Heart Association","keywords":"Kidney; Hypoxia (environmental); Inflammation; Fibrosis; Ischemia; Acute kidney injury; Endothelial stem cell; Medicine; Reperfusion injury; Kidney disease; Renal ischemia; Biology; Pharmacology; Immunology; Cancer research; Endocrinology; Pathology; Internal medicine; Chemistry; Biochemistry","score_opus":0.028038415819643007,"score_gpt":0.30630144430687034,"score_spread":0.27826302848722734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131897198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96819955,0.021005949,0.0052051498,0.0007112622,0.00011612211,0.000053028314,0.00018043137,0.00016093125,0.004367504],"genre_scores_gemma":[0.9936417,0.0037676832,0.00070222525,0.00013987996,0.0000617494,0.000017532224,0.00013451728,0.000006705369,0.001528158],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999201,0.000018034716,0.000004349933,0.000011157226,0.000012254774,0.000034069035],"domain_scores_gemma":[0.999938,0.0000039411407,0.000018905246,0.0000058240394,0.000007833164,0.00002535983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023473555,0.00020452542,0.00023519613,0.00015241739,0.00014142727,0.00030981522,0.00017560871,0.00024794837,0.0007413607],"category_scores_gemma":[0.00012835911,0.00009201661,0.0001484163,0.00007940973,0.0001885039,0.00018133526,0.0001903389,0.00047410667,0.0001476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001753398,0.00022855298,0.0013389466,0.00015682053,0.000032455268,0.00023530168,0.000037057693,0.00025974977,0.9795253,0.00063914404,0.0005504499,0.015242803],"study_design_scores_gemma":[0.00023734539,0.0032110151,0.08170467,0.000055427103,0.00012568141,0.0012752976,0.000118807606,0.0027137832,0.8938886,0.00092243013,0.015723296,0.000023760163],"about_ca_topic_score_codex":0.0004199332,"about_ca_topic_score_gemma":0.00050024694,"teacher_disagreement_score":0.0007413607,"about_ca_system_score_codex":0.00025727146,"about_ca_system_score_gemma":0.0002438547,"threshold_uncertainty_score":0.0024800897},"labels":[],"label_agreement":null},{"id":"W2132525699","doi":"10.1172/jci23219","title":"Effects of the PPARγ agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsches Krebsforschungszentrum; Takeda Pharmaceuticals North America","keywords":"Very low-density lipoprotein; Endocrinology; Lipolysis; Internal medicine; Lipoprotein lipase; Pioglitazone; Chemistry; Apolipoprotein B; Lipoprotein; Diabetes mellitus; Adipose tissue; Medicine; Type 2 diabetes; Cholesterol","score_opus":0.011448691505976404,"score_gpt":0.26987557982307353,"score_spread":0.25842688831709715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132525699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9820087,0.014013539,0.00021194782,0.0005151319,0.00017123952,0.00009220208,0.00020734986,0.00003882036,0.0027410449],"genre_scores_gemma":[0.9925333,0.004900604,0.00056012644,0.00068178406,0.000121937504,0.000088233115,0.00031219426,0.000007867679,0.0007937895],"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.99973327,0.00009158541,0.00005328788,0.000036354813,0.00004689763,0.000038520655],"domain_scores_gemma":[0.999579,0.00011678172,0.000079621655,0.000026650947,0.00004841038,0.000149526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054151047,0.00046502196,0.001438575,0.00044375157,0.0005770483,0.00063599297,0.00018712001,0.0006198301,0.001131239],"category_scores_gemma":[0.0010105069,0.00028311386,0.00074522785,0.0008174423,0.00016225701,0.000293534,0.00028145572,0.001174805,0.00021760832],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.17525205,0.014059799,0.46166834,0.0012905357,0.00312046,0.004719557,0.00059651426,0.0010113826,0.049049072,0.00020351206,0.002454694,0.28657404],"study_design_scores_gemma":[0.008591743,0.038736954,0.9315112,0.00020643901,0.003497485,0.0020129802,0.00070375024,0.0012582585,0.005350751,0.00027257876,0.007785001,0.000072696996],"about_ca_topic_score_codex":0.0013333344,"about_ca_topic_score_gemma":0.0021536506,"teacher_disagreement_score":0.001438575,"about_ca_system_score_codex":0.0003526954,"about_ca_system_score_gemma":0.00039439532,"threshold_uncertainty_score":0.0037843585},"labels":[],"label_agreement":null},{"id":"W2132585563","doi":"10.1172/jci30982","title":"Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic-pituitary-adrenal axis function","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Birth, Development, and Health","field":"Medicine","cited_by":241,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Wellcome Trust","keywords":"Offspring; Dexamethasone; Endocrinology; Primate; Adrenal function; Internal medicine; Hypothalamic–pituitary–gonadal axis; Hypothalamic–pituitary–adrenal axis; Nonhuman primate; Prenatal exposure; Function (biology); Medicine; Biology; Neuroscience; Pregnancy; Hormone; Luteinizing hormone; Genetics","score_opus":0.08850697169696502,"score_gpt":0.36930603912054266,"score_spread":0.28079906742357763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132585563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99771094,0.0010207457,0.00024634023,0.000053737524,0.000014036878,0.0000071703003,0.00013515203,0.000029622332,0.0007822116],"genre_scores_gemma":[0.9963283,0.0012502458,0.00045846566,0.000071299415,0.000008768493,0.000033585482,0.0003874211,0.000012473624,0.0014494056],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998809,0.000024143705,0.000005610831,0.000036941085,0.000025040154,0.000027375912],"domain_scores_gemma":[0.99986637,0.000035195437,0.000036489393,0.000021546099,0.000009247792,0.000031105574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083883584,0.00025066762,0.00019828796,0.00026167836,0.00018475321,0.00027681614,0.00017680027,0.00025833747,0.0018069217],"category_scores_gemma":[0.00020414435,0.00014378745,0.00012517818,0.0001075465,0.0003743066,0.00012101973,0.00020712435,0.0005760981,0.00024249003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011222541,0.00024469657,0.002964927,0.00005077012,0.000017352204,0.00068892294,0.00021433335,0.000056023273,0.9878042,0.00013487652,0.00011076413,0.0065910616],"study_design_scores_gemma":[0.000069414215,0.0074829217,0.07565868,0.000044663666,0.0000910641,0.0028122775,0.0008675793,0.00038341832,0.9055913,0.00029373544,0.006676844,0.00002805666],"about_ca_topic_score_codex":0.0007189949,"about_ca_topic_score_gemma":0.0016447932,"teacher_disagreement_score":0.0018069217,"about_ca_system_score_codex":0.00022147529,"about_ca_system_score_gemma":0.00014691912,"threshold_uncertainty_score":0.0060447454},"labels":[],"label_agreement":null},{"id":"W2132619856","doi":"10.1172/jci27414","title":"Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":349,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical School, University of Michigan; College of Pharmacy, University of Michigan; National Institutes of Health; Karolinska Institutet; Universität Heidelberg; McGill University; University of Michigan; U.S. Department of Veterans Affairs","keywords":"Nephrin; Slit diaphragm; Cell biology; Podocyte; FYN; Phosphorylation; Ectodomain; Proto-oncogene tyrosine-protein kinase Src; Src family kinase; Biology; Tyrosine phosphorylation; Actin cytoskeleton; Chemistry; Cytoskeleton; Biochemistry; Receptor; Cell","score_opus":0.09757226290251139,"score_gpt":0.37567248495538585,"score_spread":0.27810022205287444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132619856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955048,0.00066188915,0.0010515492,0.000072877556,0.00003426724,0.000032210926,0.00020908493,0.000037410544,0.002395867],"genre_scores_gemma":[0.99438536,0.00041618012,0.0011553202,0.000050105267,0.000013561523,0.000037320395,0.00052890804,0.0000066256976,0.0034067081],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996699,0.000037401656,0.000024369054,0.00004500685,0.00011314991,0.00011031113],"domain_scores_gemma":[0.9999093,0.000013183849,0.000017446466,0.000012165723,0.000006977132,0.00004087316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001400517,0.00020375349,0.00019959129,0.00014420609,0.00014818113,0.00023350825,0.000110370434,0.00023391872,0.0021365078],"category_scores_gemma":[0.00012851195,0.00012099574,0.00021256262,0.00014866119,0.00018888281,0.00011531705,0.00020292928,0.00044449326,0.00035440407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001902912,0.000049612507,0.00024765736,0.000026882068,0.0000061298006,0.0002113497,0.000008321436,0.000036402806,0.9977906,0.00013134595,0.00007759883,0.0012237548],"study_design_scores_gemma":[0.000020732343,0.00015322384,0.0116346935,0.0000024495562,0.000006558079,0.0007356835,0.000017064762,0.00052262977,0.98517054,0.000054461092,0.0016791637,0.0000027511464],"about_ca_topic_score_codex":0.00035882572,"about_ca_topic_score_gemma":0.001586493,"teacher_disagreement_score":0.0021365078,"about_ca_system_score_codex":0.00038531754,"about_ca_system_score_gemma":0.00024936086,"threshold_uncertainty_score":0.007147312},"labels":[],"label_agreement":null},{"id":"W2133227855","doi":"10.1172/jci19504","title":"Mammary-specific deletion of parathyroid hormone–related protein preserves bone mass during lactation","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Yale University","keywords":"Lactation; Endocrinology; Internal medicine; Parathyroid hormone-related protein; Mammary gland; Bone resorption; Bone remodeling; Offspring; Parathyroid hormone; Biology; Genetically modified mouse; Transgene; Calcium; Pregnancy; Medicine; Gene; Cancer","score_opus":0.06999822060789593,"score_gpt":0.35805086183207524,"score_spread":0.2880526412241793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133227855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933897,0.001710396,0.0031616525,0.00020611206,0.000024117091,0.000021224923,0.00022015256,0.00014792584,0.0011187822],"genre_scores_gemma":[0.9919887,0.0013860805,0.0029400887,0.00007407619,0.00002562836,0.000046376743,0.0004598502,0.000048261638,0.0030309157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998578,0.000025177189,0.000014275953,0.00002728515,0.00003775826,0.00003764342],"domain_scores_gemma":[0.9997478,0.00004709529,0.000082137056,0.000043213364,0.000016478705,0.000063260246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022812725,0.00019027956,0.0002748962,0.00022202205,0.000107096304,0.00029342822,0.00031100577,0.00026986995,0.00078054593],"category_scores_gemma":[0.00026484695,0.00018566745,0.00014072546,0.00009801011,0.000297963,0.00017584449,0.00018389184,0.00045491307,0.0003094902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017757106,0.000026446469,0.0004489597,0.00001720399,0.0000033323893,0.00006540865,0.0000119944,0.000032625183,0.9964142,0.00008641388,0.00003086199,0.0026850286],"study_design_scores_gemma":[0.00013330519,0.0009516318,0.020019535,0.00002143795,0.000040981493,0.0016043938,0.000059188467,0.00057984464,0.9682552,0.00018814487,0.008137896,0.00000849202],"about_ca_topic_score_codex":0.00024754208,"about_ca_topic_score_gemma":0.000410578,"teacher_disagreement_score":0.00078054593,"about_ca_system_score_codex":0.00017691072,"about_ca_system_score_gemma":0.0002518794,"threshold_uncertainty_score":0.0026112199},"labels":[],"label_agreement":null},{"id":"W2133234260","doi":"10.1172/jci38924","title":"The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health; School of Medicine, Indiana University; Ball Brothers Foundation","keywords":"Islet; Proinflammatory cytokine; Streptozotocin; Beta cell; Biology; Inflammation; Messenger RNA; Gene knockdown; Endocrinology; Internal medicine; Diabetes mellitus; Immunology; Biochemistry; Medicine; Apoptosis; Gene","score_opus":0.028626875519798648,"score_gpt":0.3208163572318547,"score_spread":0.29218948171205605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133234260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98854756,0.0029658698,0.0052960967,0.00034137507,0.00009034797,0.00007449426,0.0005938756,0.00020107561,0.0018892558],"genre_scores_gemma":[0.9893974,0.0023490263,0.0042442596,0.00019469766,0.000033452478,0.000107260275,0.0005025721,0.000043170257,0.0031281572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998242,0.000030256133,0.000017689763,0.00004282591,0.000045084813,0.00004003671],"domain_scores_gemma":[0.9997825,0.000017352748,0.000092633054,0.000027344364,0.000011822841,0.00006840901],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019439527,0.0004775233,0.00026798696,0.0004186779,0.0001788074,0.00030275973,0.0002557793,0.0004586997,0.0014100838],"category_scores_gemma":[0.00014995545,0.0002813004,0.00037809953,0.00019618565,0.0003358995,0.00032387464,0.000305939,0.0011860434,0.0002729987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041411008,0.00006527858,0.0001919812,0.000048752507,0.000010750939,0.00007752548,0.00001290723,0.000045593395,0.9967894,0.00012249485,0.0000424167,0.0021788694],"study_design_scores_gemma":[0.00013912308,0.0021628065,0.013308264,0.00003457556,0.00006454183,0.00078508834,0.00006474898,0.0010724901,0.97532916,0.0002507805,0.0067726374,0.000015675858],"about_ca_topic_score_codex":0.00021651515,"about_ca_topic_score_gemma":0.00046484117,"teacher_disagreement_score":0.0014100838,"about_ca_system_score_codex":0.0002098571,"about_ca_system_score_gemma":0.00017419351,"threshold_uncertainty_score":0.004717231},"labels":[],"label_agreement":null},{"id":"W2133742666","doi":"10.1172/jci40778","title":"Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph's Hospital; McMaster University","funders":"Prostate Cancer Canada; Cancer Research Society","keywords":"PTEN; Tensin; Carcinogenesis; DU145; Cancer research; Biology; Gene knockdown; PI3K/AKT/mTOR pathway; Chemistry; Cancer cell; Cancer; Cell culture; Cell biology; Signal transduction; LNCaP; Genetics","score_opus":0.036079553736025366,"score_gpt":0.3528210182621844,"score_spread":0.31674146452615903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133742666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98928714,0.0032114738,0.0019166812,0.00034711033,0.00007400794,0.0000679045,0.00092755293,0.00045693066,0.0037110522],"genre_scores_gemma":[0.992409,0.0014102169,0.0014656448,0.00009617049,0.000009216097,0.00010481167,0.0015494525,0.000019092571,0.0029363818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987876,0.000018598023,0.000013387837,0.000022436363,0.000033214306,0.00003363677],"domain_scores_gemma":[0.9999608,0.00000469968,0.000010480241,0.0000051402403,0.0000038487606,0.000015068607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018074007,0.00035647178,0.0003280553,0.00032306853,0.00017679959,0.00025529397,0.00017622096,0.00017716106,0.0018533936],"category_scores_gemma":[0.0000995344,0.0001379203,0.00028155665,0.0002989632,0.00019777306,0.00011665574,0.00020568847,0.0007294661,0.00050351815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009187899,0.00032812945,0.0007373962,0.000199814,0.000029139757,0.00016963978,0.000034804685,0.00036472964,0.98786724,0.00028588696,0.0010397336,0.008024753],"study_design_scores_gemma":[0.00015670723,0.0013785989,0.010666472,0.000012899073,0.000060750197,0.00063968566,0.000043752134,0.0039096544,0.97361994,0.00010171231,0.009399238,0.0000106854695],"about_ca_topic_score_codex":0.0007634363,"about_ca_topic_score_gemma":0.0015009472,"teacher_disagreement_score":0.0018533936,"about_ca_system_score_codex":0.0003917642,"about_ca_system_score_gemma":0.00050337275,"threshold_uncertainty_score":0.006200254},"labels":[],"label_agreement":null},{"id":"W2134179936","doi":"10.1172/jci59176","title":"Hypoxic pulmonary vasoconstriction requires connexin 40–mediated endothelial signal conduction","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Vasoconstriction; Depolarization; Hypoxic pulmonary vasoconstriction; Hypoxia (environmental); Apocynin; Connexin; Vasodilation; Cell biology; Lung; Chemistry; Gap junction; Arteriole; Endothelium; Biology; Internal medicine; NADPH oxidase; Endocrinology; Reactive oxygen species; Oxygen; Medicine; Intracellular; Circulatory system","score_opus":0.20023970836110885,"score_gpt":0.3830804311125014,"score_spread":0.18284072275139254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134179936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98646355,0.0025605073,0.0078941155,0.0003606269,0.00005879621,0.00003065349,0.000102156955,0.00007524403,0.002454359],"genre_scores_gemma":[0.99644756,0.0011750906,0.0011922007,0.000051923478,0.00001927408,0.000018549232,0.00008602194,0.0000043928558,0.001004972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999019,0.000019061214,0.000008246695,0.00002464722,0.000018395313,0.000027869359],"domain_scores_gemma":[0.999889,0.000018185483,0.00003274658,0.00001417822,0.00001735011,0.000028419805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019162672,0.00015254547,0.00017376221,0.00010878492,0.00017984031,0.00019920003,0.00010799713,0.0002610427,0.0010706481],"category_scores_gemma":[0.00022774216,0.00011458363,0.00018112063,0.00006394514,0.0002955201,0.00031706534,0.0002510855,0.00035164974,0.00015800595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014634687,0.000028060353,0.0008636557,0.00005064857,0.000010481438,0.00040728776,0.0000444741,0.00011574935,0.9948309,0.0007905817,0.00008782582,0.002624056],"study_design_scores_gemma":[0.00007677735,0.0010885898,0.12478001,0.000058990652,0.00006372185,0.0039763125,0.0002454449,0.0045316424,0.8545928,0.0026442884,0.0079195425,0.000021951353],"about_ca_topic_score_codex":0.00062266295,"about_ca_topic_score_gemma":0.0005691826,"teacher_disagreement_score":0.0010706481,"about_ca_system_score_codex":0.00020456678,"about_ca_system_score_gemma":0.0002415147,"threshold_uncertainty_score":0.0035817027},"labels":[],"label_agreement":null},{"id":"W2134283161","doi":"10.1172/jci14596","title":"Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":278,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; American Heart Association","keywords":"Internal medicine; Endocrinology; CD36; Insulin resistance; Hyperinsulinemia; Insulin; Biology; Glucose uptake; Fructose; Triglyceride; Fatty acid; Glycogen; Glycogen synthase; Medicine; Cholesterol; Biochemistry","score_opus":0.05133764479509177,"score_gpt":0.33714139656338066,"score_spread":0.28580375176828887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134283161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99794966,0.00031330754,0.0009599544,0.00011077414,0.0000153233,0.00001173776,0.00029731845,0.000055138185,0.0002868414],"genre_scores_gemma":[0.993694,0.0006781766,0.0025267955,0.00010685716,0.000015472358,0.000059221966,0.00060861773,0.00011488715,0.0021958991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996257,0.00007514375,0.00005556913,0.00009240379,0.00006447423,0.00008675029],"domain_scores_gemma":[0.9995571,0.00006258838,0.00014296146,0.00004517622,0.000022805309,0.00016941625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026073898,0.00065158645,0.00047812882,0.0009971148,0.00026784162,0.00049026514,0.00034921765,0.0006796903,0.0022407006],"category_scores_gemma":[0.00033714334,0.0005182059,0.00035668557,0.00031873438,0.0007394595,0.00035067456,0.00041620657,0.0010463748,0.00058259116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005597156,0.00004669112,0.00041226388,0.00001892142,0.0000064946685,0.00010913018,0.000022890774,0.00003593858,0.998197,0.00007099022,0.00002149368,0.0004982956],"study_design_scores_gemma":[0.0003309698,0.0009736538,0.02147131,0.000035136643,0.0001122898,0.002474166,0.00014353363,0.0015517991,0.97034,0.0003311913,0.0022001101,0.000035737274],"about_ca_topic_score_codex":0.000541043,"about_ca_topic_score_gemma":0.000658565,"teacher_disagreement_score":0.0022407006,"about_ca_system_score_codex":0.0003763635,"about_ca_system_score_gemma":0.0001672464,"threshold_uncertainty_score":0.0074958205},"labels":[],"label_agreement":null},{"id":"W2135277389","doi":"10.1172/jci18370","title":"Hyperosmolarity enhances the lung capillary barrier","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Columbia College","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Stony Wold-Herbert Fund","keywords":"Actin cytoskeleton; Barrier function; Proinflammatory cytokine; Lung; Cell biology; Actin; Cytoskeleton; Chemistry; Tight junction; Endothelial stem cell; Biophysics; Inflammation; Medicine; Immunology; Biology; Cell; Internal medicine; Biochemistry; In vitro","score_opus":0.08616369987223477,"score_gpt":0.38664824658543306,"score_spread":0.3004845467131983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135277389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935694,0.0023128006,0.0030632934,0.00018263017,0.000012167944,0.0000271411,0.000033382817,0.000062246036,0.00073692325],"genre_scores_gemma":[0.9969099,0.0009022813,0.0016425162,0.000058655,0.00001385569,0.000012379729,0.000028464592,0.000008372702,0.00042338064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999858,0.000041929925,0.0000064309847,0.000017474795,0.00003192448,0.00004413269],"domain_scores_gemma":[0.9998605,0.000042732572,0.000040886916,0.000009664975,0.00001544485,0.000030685034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018683671,0.00022356617,0.00022441379,0.00012630898,0.00014129409,0.000341753,0.000104673156,0.0002607243,0.000905199],"category_scores_gemma":[0.00017114542,0.00011321754,0.00014967604,0.000051107076,0.00027055782,0.00037820247,0.000251701,0.00046591205,0.000089497626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008091892,0.000010515563,0.000109215696,0.000019533922,0.000003046474,0.00004305965,0.0000059532495,0.00005197087,0.99849725,0.00006718947,0.00001979776,0.0010914251],"study_design_scores_gemma":[0.000024052222,0.0008000788,0.0051941313,0.000005675315,0.000016410593,0.0004591356,0.000028732766,0.001254106,0.9903985,0.00012892774,0.0016839284,0.0000062822046],"about_ca_topic_score_codex":0.00027454732,"about_ca_topic_score_gemma":0.0005635255,"teacher_disagreement_score":0.000905199,"about_ca_system_score_codex":0.00022144616,"about_ca_system_score_gemma":0.0001775246,"threshold_uncertainty_score":0.0030281544},"labels":[],"label_agreement":null},{"id":"W2135504026","doi":"10.1172/jci39703","title":"Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":322,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Cancer research; Fibroblast growth factor receptor 4; Oncogene; Biology; Receptor tyrosine kinase; Metastasis; Cancer; Signal transduction; Cell cycle; Fibroblast growth factor receptor; Receptor; Cell biology; Fibroblast growth factor; Genetics","score_opus":0.1159110004766093,"score_gpt":0.40958608121143014,"score_spread":0.29367508073482085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135504026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99497664,0.0007996462,0.0025594912,0.000095052106,0.000033712542,0.000093051895,0.0005985935,0.00010329161,0.0007404545],"genre_scores_gemma":[0.9927834,0.00079256116,0.0033605064,0.000040625633,0.000007774463,0.00007945682,0.0008392285,0.000027805254,0.0020686742],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997981,0.000029767194,0.000023771752,0.000039933322,0.00006392826,0.000044624267],"domain_scores_gemma":[0.99992096,0.000012332938,0.000025873678,0.000010249035,0.000008782891,0.000021795613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019114568,0.0004150188,0.00033994595,0.00049796357,0.00021735347,0.00016888208,0.00021501398,0.00037558,0.0018029743],"category_scores_gemma":[0.00011639974,0.00021417571,0.00060489035,0.00014814934,0.0002082801,0.00014021968,0.00020307019,0.0004932936,0.00040437607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008866095,0.00005493247,0.00024372684,0.000019690815,0.0000093919325,0.00010477814,0.000007392137,0.0000744923,0.9987595,0.000058911177,0.000037172253,0.0005413211],"study_design_scores_gemma":[0.000039156217,0.00089529913,0.0067361565,0.000008692926,0.000048642338,0.0013512367,0.000025863455,0.0011551719,0.98786515,0.000044778957,0.0018220624,0.00000773952],"about_ca_topic_score_codex":0.00092430273,"about_ca_topic_score_gemma":0.0016169777,"teacher_disagreement_score":0.0018029743,"about_ca_system_score_codex":0.00035436556,"about_ca_system_score_gemma":0.00027243007,"threshold_uncertainty_score":0.006031573},"labels":[],"label_agreement":null},{"id":"W2135521893","doi":"10.1172/jci45235","title":"Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":185,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; China Scholarship Council; Ragon Institute of MGH, MIT and Harvard; Centre Hospitalier Universitaire Vaudois; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Biology; Transcriptome; Immunology; Virology; Simian immunodeficiency virus; Immunodeficiency; Viral load; Rhesus macaque; Macaque; Gene; Immune system; Genetics; Virus; Gene expression","score_opus":0.20280587566445654,"score_gpt":0.3829761279462368,"score_spread":0.18017025228178027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135521893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985989,0.00032128877,0.00024328129,0.0000130626495,0.0000029760236,0.0000072239177,0.0005527188,0.0000043359446,0.00025619724],"genre_scores_gemma":[0.9967321,0.00030844132,0.0007454204,0.000035979425,0.0000056866725,0.000047392667,0.0013070364,0.000007636959,0.00081017386],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99995446,0.000006246329,0.0000022954123,0.000015867585,0.0000068978416,0.0000141941655],"domain_scores_gemma":[0.99995136,0.0000119770675,0.000011981535,0.0000053946274,0.000007869328,0.000011308945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007567768,0.00009950261,0.00017126834,0.00027970545,0.00022532395,0.00020303826,0.000050670173,0.0001268248,0.00049598987],"category_scores_gemma":[0.00011331874,0.00006679272,0.00013126478,0.00021374994,0.00020066446,0.00009657645,0.00014570632,0.00015018055,0.00010725491],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029934006,0.000010401437,0.0108239,0.000050015202,0.000014211724,0.00011827455,0.0002351374,0.0000618945,0.9862514,0.000062675535,0.00004794733,0.002024798],"study_design_scores_gemma":[0.0000074176896,0.0003070127,0.94891864,0.000017011791,0.000033884713,0.0007657709,0.0007352774,0.0009082479,0.04625661,0.00018317712,0.0018564558,0.000010494093],"about_ca_topic_score_codex":0.00084960985,"about_ca_topic_score_gemma":0.0014115517,"teacher_disagreement_score":0.00084960985,"about_ca_system_score_codex":0.00011147543,"about_ca_system_score_gemma":0.00008922383,"threshold_uncertainty_score":0.0016893148},"labels":[],"label_agreement":null},{"id":"W2136075582","doi":"10.1172/jci13971","title":"Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada); University Health Network; University of Toronto; Canadian Heart Research Centre; Hospital for Sick Children; Heart and Stroke Foundation","funders":"Canadian Institutes of Health Research; University of Toronto; Heart and Stroke Foundation of Canada","keywords":"MAPK/ERK pathway; Jurkat cells; Myocarditis; Viral Myocarditis; Kinase; Coxsackievirus; Myocyte; T cell; Cell biology; Immune system; Biology; Chemistry; Immunology; Medicine; Virus; Internal medicine; Enterovirus","score_opus":0.1749567905483057,"score_gpt":0.43113673614328857,"score_spread":0.25617994559498286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136075582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958949,0.0009285128,0.00097642886,0.00017674985,0.000055662116,0.00006786607,0.0005535255,0.00012118113,0.0012252296],"genre_scores_gemma":[0.9918825,0.0008768269,0.0017339888,0.00015028096,0.000034914505,0.00022857054,0.0009352945,0.00005774744,0.0040998817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997068,0.0000469607,0.000032238917,0.000071804556,0.00004978682,0.000092243994],"domain_scores_gemma":[0.9996518,0.000031851967,0.00009514893,0.000029243145,0.00001958484,0.00017250126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031752212,0.0009326453,0.00052710803,0.0010836523,0.00046699605,0.00052154576,0.0003099727,0.0010830078,0.0033035744],"category_scores_gemma":[0.00022415868,0.0005805002,0.00058448996,0.00030618437,0.00053178635,0.00050667167,0.0002818107,0.0021796653,0.0007552832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011410558,0.00045712432,0.00042784816,0.00005073417,0.000011621049,0.00014487181,0.000042560605,0.00006438937,0.99660635,0.00021555884,0.00010430526,0.00073368923],"study_design_scores_gemma":[0.00079383707,0.005988032,0.052119363,0.00007207435,0.00011758956,0.002665324,0.00024484642,0.0031266974,0.9291533,0.0005542396,0.005114114,0.000050519586],"about_ca_topic_score_codex":0.00039806732,"about_ca_topic_score_gemma":0.00058220094,"teacher_disagreement_score":0.0033035744,"about_ca_system_score_codex":0.000495454,"about_ca_system_score_gemma":0.00025240876,"threshold_uncertainty_score":0.011051595},"labels":[],"label_agreement":null},{"id":"W2138822762","doi":"10.1172/jci64704","title":"PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8+ T cells in mice","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Cytotoxic T cell; DNA vaccination; Virology; Antigen; CD8; Biology; Vaccination; Vaccinia; Immunology; Cross-presentation; T cell; Immunity; Antibody; Immunization; Immune system; MHC class I; Recombinant DNA","score_opus":0.04905012180690572,"score_gpt":0.3121046314346811,"score_spread":0.2630545096277754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138822762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97549176,0.0018155895,0.014679337,0.00069050223,0.00019245177,0.0003617321,0.0008063236,0.0011125668,0.0048497096],"genre_scores_gemma":[0.9721397,0.0016288062,0.015756104,0.00033600524,0.00008808282,0.00029626972,0.0008161949,0.00009371988,0.008845027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969065,0.000046800957,0.000027183954,0.000092329276,0.000059056092,0.00008392458],"domain_scores_gemma":[0.99983394,0.00002900603,0.000050278824,0.000028506402,0.000017872975,0.00004032338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003564726,0.0007722126,0.00044146247,0.0007929765,0.00020101549,0.00040270187,0.0003414669,0.00078950473,0.0014296576],"category_scores_gemma":[0.00017093861,0.00039589038,0.0002953618,0.00016846631,0.00046323103,0.00048180146,0.00023278891,0.001863503,0.00058458105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036649476,0.00042996372,0.00012717997,0.00007682397,0.000008567763,0.000029061037,0.000028788143,0.00022146234,0.99307513,0.00041805132,0.00014204522,0.005076515],"study_design_scores_gemma":[0.0002216045,0.0029477596,0.00088854245,0.00002777899,0.000031020038,0.00021248727,0.000016556789,0.0024196187,0.98913366,0.00022589683,0.003867635,0.000007528042],"about_ca_topic_score_codex":0.00024960254,"about_ca_topic_score_gemma":0.00032498597,"teacher_disagreement_score":0.0014296576,"about_ca_system_score_codex":0.00037371455,"about_ca_system_score_gemma":0.00032451164,"threshold_uncertainty_score":0.004782617},"labels":[],"label_agreement":null},{"id":"W2140002624","doi":"10.1172/jci33637","title":"Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Center for Research Resources; National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health","keywords":"Fenoldopam; Receptor; Endocrinology; Angiotensin II; Dopamine; Internal medicine; Cell biology; Biology; Dopamine receptor; Ubiquitin; Proteasome; Blood pressure; Biochemistry; Medicine; Gene","score_opus":0.0522575361822564,"score_gpt":0.3130316294920882,"score_spread":0.2607740933098318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140002624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9535334,0.01465552,0.024392629,0.0005943781,0.00010233607,0.00008246808,0.0013169756,0.0004069873,0.0049153315],"genre_scores_gemma":[0.98570204,0.0043668067,0.005201159,0.00011723966,0.000014738513,0.000050440456,0.0011229797,0.000018891518,0.0034057961],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99966395,0.000084099476,0.000034477347,0.00009191943,0.00007838321,0.00004717441],"domain_scores_gemma":[0.99993205,0.0000101600735,0.000023500956,0.00001474441,0.0000065526465,0.000013034277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043183894,0.000378815,0.00030785165,0.00031388985,0.00022711328,0.0005709939,0.00019140648,0.00037772575,0.0018527418],"category_scores_gemma":[0.0001425396,0.00021851152,0.00033726872,0.00013346608,0.00025206775,0.00021909458,0.00019874699,0.00043421306,0.00068919035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031922458,0.000058002148,0.0007023966,0.00007584556,0.000037247723,0.0001970959,0.00003529518,0.0001262102,0.99298495,0.00071108976,0.00030411046,0.004448486],"study_design_scores_gemma":[0.00007390314,0.0005038692,0.009602592,0.000018455408,0.00006585467,0.0017035737,0.000054263644,0.0022558111,0.9712071,0.00031614676,0.014183998,0.000014468393],"about_ca_topic_score_codex":0.0010432185,"about_ca_topic_score_gemma":0.0013166944,"teacher_disagreement_score":0.0018527418,"about_ca_system_score_codex":0.00045355046,"about_ca_system_score_gemma":0.00027405642,"threshold_uncertainty_score":0.0061980486},"labels":[],"label_agreement":null},{"id":"W2140528350","doi":"10.1172/jci29255","title":"Role for protease activity in visceral pain in irritable bowel syndrome","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":580,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Fondation pour la Recherche Médicale; Alberta Heritage Foundation for Medical Research; Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation","keywords":"Irritable bowel syndrome; Medicine; Proteases; Hyperalgesia; Visceral pain; Protease; Internal medicine; Protease-activated receptor 2; Tryptase; Sensitization; Allodynia; Gastroenterology; Endocrinology; Immunology; Nociception; Receptor; Mast cell; Chemistry; Enzyme; Biochemistry","score_opus":0.06498046728787583,"score_gpt":0.3771222736920648,"score_spread":0.312141806404189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140528350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9759493,0.021479059,0.0011685473,0.0003021218,0.000029365523,0.000015647636,0.00008125823,0.00003350956,0.0009413745],"genre_scores_gemma":[0.9971066,0.0020885954,0.0005014361,0.000042935757,0.00003621537,0.0000063127154,0.000052754294,0.0000023124526,0.00016280024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984324,0.00006657335,0.000016939714,0.000022763896,0.000029629808,0.000020762314],"domain_scores_gemma":[0.9997743,0.00005782244,0.00009112931,0.000014596648,0.00002192295,0.000040242336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026074718,0.00049077976,0.00037228988,0.00037685788,0.00017066272,0.0003883675,0.00012045204,0.00035002455,0.0010952251],"category_scores_gemma":[0.000567197,0.00012480989,0.00020733991,0.00017704134,0.00034518575,0.0002677469,0.00027523527,0.00045881647,0.00019705758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006470356,0.00023856424,0.070825554,0.0008292563,0.00021293409,0.009393054,0.00028677634,0.00022285651,0.87125695,0.000481484,0.00040690854,0.03937531],"study_design_scores_gemma":[0.000287388,0.0041693193,0.8458811,0.00010812545,0.0002749445,0.032407656,0.00032898955,0.0015159679,0.11032071,0.0006902487,0.00398538,0.000030080095],"about_ca_topic_score_codex":0.00012377168,"about_ca_topic_score_gemma":0.00010418283,"teacher_disagreement_score":0.0010952251,"about_ca_system_score_codex":0.00015351891,"about_ca_system_score_gemma":0.000080921396,"threshold_uncertainty_score":0.0036638975},"labels":[],"label_agreement":null},{"id":"W2141478377","doi":"10.1172/jci39922","title":"Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":517,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Menzies Centre for Australian Studies, King's College London, University of London; National Institute for Health and Care Research; Anthony Nolan; Medical Research Council; Immune Tolerance Network; Deutsche Forschungsgemeinschaft; King's College London; King's College Hospital NHS Foundation Trust","keywords":"Biomarker; Transplantation; Medicine; Gene signature; Immunology; Microarray; Renal transplant; Gene expression profiling; Biology; Gene expression; Internal medicine; Gene","score_opus":0.09714995730756538,"score_gpt":0.4166318567206759,"score_spread":0.3194818994131105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141478377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912676,0.00040397045,0.0075951917,0.00004613124,0.0000148886,0.000063252264,0.00017174639,0.00003642102,0.000400787],"genre_scores_gemma":[0.9929254,0.00018208117,0.0060318313,0.000086948996,0.000016446267,0.000067382054,0.00038386477,0.000008655497,0.00029750096],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995413,0.00016462698,0.000040706822,0.0000935075,0.00011885566,0.000041065745],"domain_scores_gemma":[0.99941015,0.00017075248,0.00019058154,0.00007844623,0.00008596993,0.000064046835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011365494,0.0003614007,0.00052651874,0.0006990493,0.00016377876,0.00054746494,0.00019945223,0.00033778726,0.0007472122],"category_scores_gemma":[0.0015680037,0.00012587602,0.00018756819,0.00026375384,0.00021145004,0.00025920296,0.00028699441,0.0003610995,0.00020396651],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015251901,0.00056422484,0.20587315,0.00012337285,0.00012119874,0.00018902805,0.00014927874,0.0019310192,0.7349451,0.00016107483,0.00026931474,0.054147977],"study_design_scores_gemma":[0.00007424824,0.011167007,0.45574808,0.000054902812,0.0002683,0.002257036,0.0003071367,0.014963913,0.5117677,0.00073300226,0.002594556,0.00006408672],"about_ca_topic_score_codex":0.00014295078,"about_ca_topic_score_gemma":0.00016572008,"teacher_disagreement_score":0.0011365494,"about_ca_system_score_codex":0.00011055297,"about_ca_system_score_gemma":0.00013479585,"threshold_uncertainty_score":0.006010771},"labels":[],"label_agreement":null},{"id":"W2141917858","doi":"10.1172/jci15595","title":"Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":473,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Endocrinology; Internal medicine; Glucagon-like peptide-1; Catecholamine; Adrenal medulla; Receptor; Biology; Medicine; Type 2 diabetes; Diabetes mellitus","score_opus":0.06906751738822468,"score_gpt":0.31581175006090023,"score_spread":0.24674423267267553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141917858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855004,0.006012866,0.003083547,0.00023492362,0.00015419557,0.000050041886,0.00018756215,0.00015193665,0.004624379],"genre_scores_gemma":[0.99029934,0.004775632,0.0020435413,0.00016476371,0.00012373853,0.00006373008,0.00020550791,0.000012893604,0.0023108562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999305,0.000016352518,0.000004177305,0.000015403873,0.000019133955,0.00001431716],"domain_scores_gemma":[0.99993396,0.000015315889,0.000018636245,0.0000044823532,0.0000061212077,0.000021616877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007634664,0.00032125457,0.00027333442,0.00014328431,0.00009315703,0.00015475776,0.00009071412,0.0001852284,0.002394471],"category_scores_gemma":[0.00017282795,0.00009525573,0.00013908553,0.000103227845,0.00020972587,0.000109747874,0.00013658224,0.00049726205,0.00023145898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005597549,0.000100153055,0.00047448892,0.00007691241,0.000010132497,0.00013358804,0.00001585994,0.00002398242,0.98472923,0.000048734793,0.00012197271,0.013705329],"study_design_scores_gemma":[0.00023102366,0.008393917,0.14210266,0.00005658952,0.00007749941,0.0024167646,0.0001312127,0.0010261841,0.8385673,0.00042486726,0.0065457327,0.000026211548],"about_ca_topic_score_codex":0.00013786861,"about_ca_topic_score_gemma":0.0002671049,"teacher_disagreement_score":0.002394471,"about_ca_system_score_codex":0.00014116737,"about_ca_system_score_gemma":0.00008742427,"threshold_uncertainty_score":0.008010268},"labels":[],"label_agreement":null},{"id":"W2141919622","doi":"10.1172/jci33166","title":"No evidence that skewing of X chromosome inactivation patterns is transmitted to offspring in humans","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"X-inactivation; Biology; Skewed X-inactivation; Offspring; X chromosome; Haematopoiesis; Genetics; Immunology; Pregnancy; Gene; Stem cell","score_opus":0.07610582945069332,"score_gpt":0.3641251878865568,"score_spread":0.28801935843586346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141919622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940836,0.002915052,0.00096688094,0.000116079995,0.000022683846,0.000007608223,0.00023088786,0.000030202369,0.0016272373],"genre_scores_gemma":[0.9965533,0.0017192181,0.00064068695,0.00010003819,0.000037614813,0.000009403945,0.00021655967,0.0000117724885,0.0007113345],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993711,0.00014316448,0.000050942446,0.00020908166,0.0001853557,0.000040281964],"domain_scores_gemma":[0.9982741,0.0005948498,0.0005401674,0.00031981067,0.00013802915,0.00013309348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005469775,0.00024295218,0.00043270676,0.0008526982,0.00033288216,0.0004176666,0.00027451618,0.00052763405,0.0033764679],"category_scores_gemma":[0.0035509465,0.0002700908,0.00012088571,0.00047118854,0.00067450834,0.00029201357,0.00031856302,0.00029613802,0.00039478426],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077634276,0.000081489896,0.9038194,0.00017186283,0.00023952265,0.0034248135,0.00070496125,0.00022068509,0.037496123,0.0008405005,0.00068761886,0.051536664],"study_design_scores_gemma":[0.000035136745,0.00064812985,0.96291554,0.000046881418,0.00007708945,0.024766013,0.00019288753,0.00018570859,0.0059006508,0.00068903173,0.004516417,0.000026575548],"about_ca_topic_score_codex":0.00041983835,"about_ca_topic_score_gemma":0.000421363,"teacher_disagreement_score":0.0033764679,"about_ca_system_score_codex":0.0001368012,"about_ca_system_score_gemma":0.00013690065,"threshold_uncertainty_score":0.011295378},"labels":[],"label_agreement":null},{"id":"W2142414068","doi":"10.1172/jci20518","title":"Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Internal medicine; Endocrinology; Incretin; Insulin; Receptor; Secretion; Insulin oscillation; Islet; Hormone; In vivo; Biology; Chemistry; Diabetes mellitus; Medicine; Type 2 diabetes","score_opus":0.0666178616087237,"score_gpt":0.3488320683657076,"score_spread":0.28221420675698394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142414068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99285287,0.0011021801,0.0042254645,0.00016934313,0.000037140795,0.00002090583,0.00046154967,0.00016201129,0.00096839294],"genre_scores_gemma":[0.98789036,0.0013809649,0.005105793,0.00017621595,0.000031469288,0.000110142384,0.0006298109,0.0001573547,0.004517821],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995797,0.000055906337,0.000060342838,0.00013563549,0.00008712652,0.00008127446],"domain_scores_gemma":[0.99952507,0.000048076145,0.00019636225,0.000054279,0.000019981195,0.00015615819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029277572,0.0013087521,0.0005837604,0.000835589,0.00017497275,0.0007105986,0.0005821793,0.00065672543,0.0015054933],"category_scores_gemma":[0.00024174602,0.0005248041,0.00044138503,0.00027515605,0.0008303314,0.00070148887,0.00046824728,0.0018746369,0.00042195705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059762277,0.000048769456,0.0003277255,0.000031050935,0.000007916211,0.00013794977,0.000020053614,0.00008121862,0.99733657,0.0002668392,0.0000315655,0.0011126224],"study_design_scores_gemma":[0.00024082181,0.00073253893,0.0140295895,0.00003957316,0.000120158045,0.0014622757,0.00009040849,0.0021469847,0.97792953,0.0004162703,0.0027682798,0.00002361899],"about_ca_topic_score_codex":0.00023336247,"about_ca_topic_score_gemma":0.0003040768,"teacher_disagreement_score":0.0015054933,"about_ca_system_score_codex":0.0003043947,"about_ca_system_score_gemma":0.00022295097,"threshold_uncertainty_score":0.005036354},"labels":[],"label_agreement":null},{"id":"W2142713036","doi":"10.1172/jci39395","title":"The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; Elsa U. Pardee Foundation; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Deutsche Krebshilfe; National Heart, Lung, and Blood Institute; Emerald Foundation; Memorial Sloan-Kettering Cancer Center; Deutsche Forschungsgemeinschaft; Commonwealth Foundation; American Association for Cancer Research","keywords":"Cytolysis; Fas ligand; Host (biology); Ligand (biochemistry); Immunology; Graft-versus-host disease; Virology; Biology; Disease; Chemistry; Medicine; Cell biology; Pathology; Cytotoxicity; Apoptosis; Biochemistry; Genetics; In vitro; Receptor; Programmed cell death","score_opus":0.06071592026586368,"score_gpt":0.34689813843789363,"score_spread":0.28618221817202993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142713036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909112,0.0046151113,0.002562547,0.000113231974,0.000030238374,0.000028230028,0.00035740252,0.00017360722,0.0012084686],"genre_scores_gemma":[0.9962054,0.0008560698,0.0012570806,0.00003323258,0.000008515069,0.000027759446,0.00040366844,0.000015361307,0.0011929435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996892,0.000056063032,0.00005663362,0.000046344354,0.00009502653,0.00005684156],"domain_scores_gemma":[0.9996395,0.000037286914,0.00017086595,0.00003249643,0.000026668476,0.00009311818],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015227677,0.00038084888,0.00025042088,0.00026770326,0.00014405463,0.0005302234,0.000164462,0.0003220184,0.0009730125],"category_scores_gemma":[0.00020521166,0.00016011653,0.00015097974,0.00011456527,0.00023981188,0.00025131422,0.00022286769,0.00054980716,0.0004042315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011317876,0.000022048369,0.00046046166,0.000034695953,0.000003625376,0.000078200326,0.000011293771,0.00009318206,0.9973362,0.00012109835,0.000020833053,0.0017052079],"study_design_scores_gemma":[0.000048162605,0.00063821673,0.013660284,0.000022129152,0.000032118358,0.0014815242,0.000054295153,0.0013641433,0.97790504,0.00017917802,0.0046074498,0.000007399688],"about_ca_topic_score_codex":0.00018571278,"about_ca_topic_score_gemma":0.00034712072,"teacher_disagreement_score":0.0009730125,"about_ca_system_score_codex":0.00036350204,"about_ca_system_score_gemma":0.00024266302,"threshold_uncertainty_score":0.0032550693},"labels":[],"label_agreement":null},{"id":"W2143398582","doi":"10.1172/jci20806","title":"Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; McGill University; Christie (Canada); University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Hypoxia (environmental); Endocrinology; Internal medicine; Biology; Contractility; Vascular smooth muscle; Messenger RNA; Downregulation and upregulation; Mesenteric arteries; Aorta; Chemistry; Gene; Biochemistry; Artery; Medicine","score_opus":0.05954789840692571,"score_gpt":0.33388621764346876,"score_spread":0.27433831923654306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143398582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99756455,0.000420185,0.0012570436,0.0000556267,0.000022475004,0.00001614971,0.00010866673,0.000018325449,0.00053704076],"genre_scores_gemma":[0.9966834,0.00024968377,0.0014511666,0.00003271901,0.000013625246,0.000023880826,0.00036148407,0.000010406765,0.0011736151],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998933,0.000020823616,0.00000942958,0.000028912687,0.000023426426,0.000024028623],"domain_scores_gemma":[0.9999045,0.00001910842,0.000034035933,0.000011772537,0.0000117303525,0.000018833927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000130656,0.00013362819,0.00013891626,0.00004874088,0.00006596887,0.00012850571,0.000059843398,0.00009922036,0.00090325275],"category_scores_gemma":[0.00015211858,0.00007675792,0.000098221084,0.000031602078,0.00016606443,0.000060706203,0.000089192275,0.00021064872,0.00017905408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057333582,0.000010505324,0.00015137227,0.000007772306,0.0000015701964,0.00002910025,0.0000053026743,0.000008849416,0.9992712,0.000029991885,0.000011804123,0.0004153439],"study_design_scores_gemma":[0.000033531174,0.0011978238,0.021879764,0.000007747664,0.000020796248,0.0009897406,0.000029927465,0.00048370342,0.9725637,0.00006503555,0.0027246347,0.0000036923445],"about_ca_topic_score_codex":0.00031754965,"about_ca_topic_score_gemma":0.00059566216,"teacher_disagreement_score":0.00090325275,"about_ca_system_score_codex":0.00017930284,"about_ca_system_score_gemma":0.00010566973,"threshold_uncertainty_score":0.0030216575},"labels":[],"label_agreement":null},{"id":"W2144000500","doi":"10.1172/jci10942","title":"Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and osteoporosis research","field":"Medicine","cited_by":760,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Center for Research Resources; National Institute on Aging; National Institutes of Health; Deutsches Krebsforschungszentrum","keywords":"Endocrinology; Internal medicine; Bone resorption; Bone remodeling; Osteocalcin; Estrogen; Testosterone (patch); Resorption; Hormone; Medicine; Osteopenia; Osteoporosis; Bone mineral; Biology; Alkaline phosphatase","score_opus":0.06689837600104416,"score_gpt":0.40582160781454113,"score_spread":0.338923231813497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144000500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943995,0.005167133,0.00011033397,0.000021588532,0.0000066995995,0.0000044408434,0.000024466723,0.0000031846548,0.00026255683],"genre_scores_gemma":[0.9976169,0.001671358,0.00026442416,0.000032066488,0.0000237089,0.0000059708823,0.000081539656,0.0000024599747,0.00030174438],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99976176,0.0000820841,0.000021517766,0.00002519038,0.00006872348,0.000040632018],"domain_scores_gemma":[0.9996697,0.00010464484,0.00006325252,0.000025917103,0.0000313559,0.00010511253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071649015,0.0002333885,0.00038862714,0.0006676656,0.00021209051,0.00036783968,0.00014767404,0.0001590265,0.00042476092],"category_scores_gemma":[0.0008761916,0.00026328125,0.00019231367,0.00026288768,0.00052773464,0.00020891793,0.00021845878,0.00017784906,0.00008857929],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.043764908,0.0008900396,0.6079331,0.00031698289,0.00041914164,0.0013214132,0.0014911948,0.0009078542,0.2514714,0.0007279271,0.00023289079,0.09052312],"study_design_scores_gemma":[0.00024134741,0.003558081,0.98278093,0.000011527632,0.00020608584,0.00078201265,0.00036798016,0.00038339823,0.010394409,0.00028665582,0.00097470917,0.000012862443],"about_ca_topic_score_codex":0.0017399433,"about_ca_topic_score_gemma":0.002019978,"teacher_disagreement_score":0.0017399433,"about_ca_system_score_codex":0.00018250142,"about_ca_system_score_gemma":0.0002871296,"threshold_uncertainty_score":0.003789246},"labels":[],"label_agreement":null},{"id":"W2144194261","doi":"10.1172/jci32693","title":"OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"Ministry of Education, Culture, Sports, Science and Technology; Japan Research Foundation for Clinical Pharmacology; Cell Science Research Foundation","keywords":"Natural killer T cell; CD1D; Immunology; Biology; T cell; Cancer research; Cell biology; Immune system","score_opus":0.0366424766813998,"score_gpt":0.3273371657934119,"score_spread":0.2906946891120121,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144194261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925559,0.0013721201,0.0018693142,0.00019326601,0.00004813777,0.000064578395,0.00028601542,0.00028045502,0.003330167],"genre_scores_gemma":[0.99098736,0.0011661798,0.0021884064,0.00013878375,0.00004285419,0.00008217594,0.00044633143,0.000056234257,0.004891617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996824,0.00007515345,0.00002317163,0.000048346636,0.000054045067,0.000116926865],"domain_scores_gemma":[0.99975854,0.00002683361,0.00007912534,0.000037823993,0.000017562821,0.000080193684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000263557,0.0006522658,0.0003373636,0.0005114197,0.00017572261,0.0005261701,0.00020334338,0.00039236332,0.001430581],"category_scores_gemma":[0.00019764091,0.0003338006,0.0001795742,0.00013164445,0.00038925637,0.00039975537,0.00023091873,0.0010135532,0.0006475115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009801065,0.0004183303,0.00037071822,0.00004891334,0.0000073851197,0.00012209348,0.000030620664,0.00019805352,0.9930155,0.00044264641,0.00015620119,0.0042093657],"study_design_scores_gemma":[0.0005106317,0.0042124167,0.0040275455,0.00003263737,0.000043959782,0.0009790995,0.000048790407,0.0023280932,0.9789752,0.00046957354,0.008359917,0.000012295554],"about_ca_topic_score_codex":0.00033181536,"about_ca_topic_score_gemma":0.00036416037,"teacher_disagreement_score":0.001430581,"about_ca_system_score_codex":0.0004877469,"about_ca_system_score_gemma":0.0003441151,"threshold_uncertainty_score":0.0047857165},"labels":[],"label_agreement":null},{"id":"W2144886836","doi":"10.1172/jci74572","title":"Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"Institut National de la Santé et de la Recherche Médicale; Université Paris Diderot; Agence Nationale de la Recherche; Laboratoire d'Excellence Inflamex","keywords":"Immunoreceptor tyrosine-based activation motif; Syk; Tyrosine; Inflammation; Tyrosine kinase; Protein tyrosine phosphatase; Signal transduction; Cytokine; Immune system; Receptor; Cell biology; Immunology; Chemistry; Biology; Biochemistry","score_opus":0.09379721659222151,"score_gpt":0.40539424363081883,"score_spread":0.3115970270385973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144886836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953745,0.0011331547,0.001142958,0.00012124238,0.000089146866,0.000038569626,0.00015692355,0.00017127686,0.0017723191],"genre_scores_gemma":[0.9958176,0.0007949781,0.0008532169,0.00014172572,0.0000313211,0.000042313804,0.0002337373,0.000022291897,0.0020628395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998078,0.000020844764,0.000014032428,0.000023693761,0.00004214848,0.00009150807],"domain_scores_gemma":[0.999949,0.0000043396954,0.000012285717,0.0000053796534,0.000004673929,0.000024317185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012097761,0.0004917263,0.0004039499,0.00020996075,0.00014589458,0.00024137429,0.00033673376,0.0002967355,0.0018769911],"category_scores_gemma":[0.0000999408,0.00015807587,0.00022445146,0.0001330328,0.00026654903,0.0001561191,0.00018136812,0.0011149904,0.0005003767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079010846,0.0002669573,0.000108745546,0.000050171846,0.000013191942,0.00004264458,0.00001713094,0.00014181105,0.9945261,0.00016754375,0.00019375695,0.003681921],"study_design_scores_gemma":[0.00027591444,0.004301188,0.0041985074,0.000015081026,0.000077940065,0.00030365703,0.000035786175,0.0010079921,0.9840718,0.000114396666,0.005585904,0.000011843838],"about_ca_topic_score_codex":0.0007556605,"about_ca_topic_score_gemma":0.0010245729,"teacher_disagreement_score":0.0018769911,"about_ca_system_score_codex":0.00028093375,"about_ca_system_score_gemma":0.00030465427,"threshold_uncertainty_score":0.006279111},"labels":[],"label_agreement":null},{"id":"W2145031719","doi":"10.1172/jci12433","title":"CD8+ lymphocytes respond to different HIV epitopes in seronegative and infected subjects","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":215,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Manitoba","funders":"Medical Research Council; Ontario HIV Treatment Network; Medical Research Council Canada; Elizabeth Glaser Pediatric AIDS Foundation","keywords":"Epitope; CTL*; Immunology; Cytotoxic T cell; Seroconversion; Virology; CD8; Biology; Immunodominance; HIV vaccine; Human leukocyte antigen; Medicine; Immune system; Antibody; Antigen; Genetics; Vaccine trial","score_opus":0.062280327744189484,"score_gpt":0.36693500109368093,"score_spread":0.3046546733494915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145031719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9996687,0.00007939086,0.000010187277,0.000007916084,0.0000017949642,0.0000033096942,0.000017282848,0.0000015031666,0.00020982017],"genre_scores_gemma":[0.9995259,0.00005885661,0.000021848884,0.000043729724,0.000007360147,0.000007063726,0.00006525447,0.0000011242416,0.00026884137],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997925,0.000047572743,0.000016131014,0.000048428938,0.000023750024,0.000071732065],"domain_scores_gemma":[0.9997472,0.000092893686,0.000037502316,0.000018905912,0.000016688338,0.00008674992],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029306812,0.00037184457,0.0002484894,0.00058905355,0.00042626495,0.00046182127,0.00016329443,0.00053922413,0.0013311013],"category_scores_gemma":[0.00090566004,0.0002701601,0.00010395309,0.00020071115,0.00040070867,0.00022656543,0.00028255378,0.0003572362,0.0003481939],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032459025,0.00047920045,0.9345816,0.000057806556,0.000054020755,0.0016480853,0.0019761752,0.00011952862,0.045261566,0.00011567811,0.00023081091,0.012229603],"study_design_scores_gemma":[0.00010917939,0.0018463477,0.9920461,0.000015577472,0.00003433392,0.0024102912,0.0007978169,0.00015022435,0.0019402017,0.00011395914,0.0005271752,0.00000870613],"about_ca_topic_score_codex":0.0012083777,"about_ca_topic_score_gemma":0.0010831548,"teacher_disagreement_score":0.0013311013,"about_ca_system_score_codex":0.00021588788,"about_ca_system_score_gemma":0.00011185834,"threshold_uncertainty_score":0.004452944},"labels":[],"label_agreement":null},{"id":"W2145063435","doi":"10.1172/jci64801","title":"2-Aminoadipic acid is a biomarker for diabetes risk","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":468,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Novo Nordisk Fonden; Fondation Leducq; National Institute of General Medical Sciences; American Heart Association","keywords":"Metabolite; Diabetes mellitus; Metabolomics; Metabolome; Type 2 diabetes; Internal medicine; Medicine; Endocrinology; Biomarker; Framingham Risk Score; Insulin; Glucose homeostasis; Disease; Bioinformatics; Biology; Biochemistry; Insulin resistance","score_opus":0.05191728015077023,"score_gpt":0.3455816133837177,"score_spread":0.29366433323294744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145063435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957242,0.0021065723,0.0010363117,0.00007080315,0.00001371981,0.000014440915,0.00041783604,0.000014830153,0.00060126605],"genre_scores_gemma":[0.9983524,0.0003552516,0.00093544525,0.000028361197,0.000009503898,0.0000068928484,0.00013119314,0.0000015659276,0.00017942359],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9996001,0.00014792175,0.000031886488,0.00011447437,0.00008049264,0.000025098501],"domain_scores_gemma":[0.99949956,0.0001009641,0.00024368633,0.000048585884,0.000050732797,0.000056479632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054612104,0.00028314465,0.00034767643,0.000822794,0.00021964553,0.0005333455,0.00015931882,0.00036539402,0.00070380006],"category_scores_gemma":[0.0010105112,0.00018305772,0.00017674077,0.00089819735,0.0001528804,0.00017513032,0.00023908043,0.00031420783,0.00014255033],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013019001,0.00006798932,0.9434002,0.000059633443,0.00027951485,0.00021690906,0.00008385557,0.00020678925,0.046571676,0.000085449814,0.000110856694,0.0076151476],"study_design_scores_gemma":[0.000021040609,0.0005042768,0.98842144,0.000011223306,0.00014158385,0.0011512141,0.00007065235,0.0008014115,0.007842685,0.00018119924,0.0008426026,0.000010723866],"about_ca_topic_score_codex":0.0008447933,"about_ca_topic_score_gemma":0.00087421644,"teacher_disagreement_score":0.0008447933,"about_ca_system_score_codex":0.00018703206,"about_ca_system_score_gemma":0.00016301332,"threshold_uncertainty_score":0.0028882623},"labels":[],"label_agreement":null},{"id":"W2145142784","doi":"10.1172/jci60214","title":"Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Colorado Denver; National Cancer Institute; National Institutes of Health; Crohn's and Colitis Foundation; Crohn's and Colitis Foundation of America; Deutsche Forschungsgemeinschaft; National Center for Research Resources; American Heart Association","keywords":"Nucleoside; Acute kidney injury; Blood flow; Kidney; Medicine; Renal blood flow; Transporter; Pharmacology; Cardiology; Internal medicine; Chemistry; Gene; Biochemistry","score_opus":0.02201752202727856,"score_gpt":0.314859910932585,"score_spread":0.2928423889053064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145142784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979625,0.0020885651,0.012224378,0.0011016034,0.00015999189,0.00012853074,0.0013793156,0.00040648817,0.0028860967],"genre_scores_gemma":[0.97694206,0.0021815428,0.008298543,0.0003863353,0.00004073537,0.0002874285,0.0010365634,0.00017442365,0.010652264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995763,0.00008007407,0.000041585874,0.000112252645,0.00008331724,0.00010654099],"domain_scores_gemma":[0.9996132,0.000039642364,0.00015305159,0.000035220673,0.000029892422,0.00012899266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004590398,0.0005209893,0.00041241993,0.00079008314,0.0004024162,0.0006907939,0.00052816665,0.0008551348,0.002892627],"category_scores_gemma":[0.00022037911,0.0004481417,0.00046309043,0.00024361606,0.0008124711,0.00060456875,0.00032909118,0.0016044871,0.00089455646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007358236,0.00014952113,0.00031574693,0.000051954583,0.000010654224,0.00008930095,0.000044933622,0.00013510209,0.9955623,0.00054358516,0.0001585607,0.0022024536],"study_design_scores_gemma":[0.00022791057,0.0009973182,0.0050468734,0.00003999259,0.0000712779,0.00044824017,0.000121993595,0.0025382282,0.9830192,0.00040699838,0.0070625893,0.00001944985],"about_ca_topic_score_codex":0.0006507557,"about_ca_topic_score_gemma":0.0013095576,"teacher_disagreement_score":0.002892627,"about_ca_system_score_codex":0.0006632945,"about_ca_system_score_gemma":0.0005016078,"threshold_uncertainty_score":0.0096767545},"labels":[],"label_agreement":null},{"id":"W2145444267","doi":"10.1172/jci25888","title":" B-Crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":272,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Michael Smith Health Research BC; Avon Foundation for Women; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Cancer research; MAPK/ERK pathway; Gene silencing; Biology; Breast cancer; Phenotype; Heat shock protein; Basal (medicine); Cancer; Kinase; Cell biology; Gene; Endocrinology; Genetics","score_opus":0.14144767068136457,"score_gpt":0.4501962148000962,"score_spread":0.30874854411873165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145444267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99320954,0.0034943037,0.00061800855,0.000342726,0.000032514363,0.000027791546,0.00066922593,0.000044286633,0.0015616185],"genre_scores_gemma":[0.99686027,0.0009655115,0.00047529966,0.000055684468,0.000036218786,0.0000140054235,0.000965931,0.0000042877423,0.0006227616],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99991655,0.000018882625,0.000008308351,0.000017345345,0.000025737298,0.000013082319],"domain_scores_gemma":[0.9998202,0.000025843032,0.000065723674,0.000008327412,0.00002136908,0.000058641504],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018072594,0.00021534534,0.0002630667,0.00037568493,0.00020389222,0.00025143765,0.00012189299,0.00024179833,0.00073679705],"category_scores_gemma":[0.00028771823,0.00006742499,0.000086752916,0.00047557047,0.00018758822,0.000113289025,0.00016143416,0.00028823438,0.00018242245],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016179417,0.00016820586,0.89933807,0.0001185342,0.000111300345,0.0005833729,0.00005112787,0.00022168622,0.06744819,0.00009954497,0.001316351,0.028925676],"study_design_scores_gemma":[0.000022796185,0.0003258641,0.98958594,0.000008972684,0.000052521827,0.0016752066,0.0000687268,0.00079636526,0.005616127,0.000118687676,0.0017236287,0.000005120005],"about_ca_topic_score_codex":0.0009768459,"about_ca_topic_score_gemma":0.0015294738,"teacher_disagreement_score":0.0009768459,"about_ca_system_score_codex":0.00023382193,"about_ca_system_score_gemma":0.00024631692,"threshold_uncertainty_score":0.0024648309},"labels":[],"label_agreement":null},{"id":"W2145592052","doi":"10.1172/jci28214","title":"Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":225,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Fetus; Antigen; Immunology; Presentation (obstetrics); Antigen presentation; Biology; Medicine; Pregnancy; T cell; Obstetrics; Immune system; Genetics","score_opus":0.09397941538509402,"score_gpt":0.3562095445659185,"score_spread":0.2622301291808245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145592052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948315,0.0012760926,0.0022464702,0.00008569148,0.0000062028416,0.000005220358,0.00003497349,0.000016716747,0.0014971363],"genre_scores_gemma":[0.9974896,0.00059319544,0.0013820751,0.000046760168,0.000011713769,0.0000094294555,0.000056016765,0.0000079386555,0.00040317536],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99976355,0.00007526571,0.000021638274,0.000043253458,0.00004004356,0.000056229932],"domain_scores_gemma":[0.9997552,0.000111528076,0.00005435947,0.00003148918,0.000012505193,0.000034886074],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024048118,0.00015741464,0.00019831804,0.000113249494,0.00010006944,0.0004645552,0.00017069855,0.0002649836,0.0012615409],"category_scores_gemma":[0.0004944611,0.00015598726,0.000098079385,0.00007483367,0.0002674795,0.00032552768,0.0003796836,0.000579533,0.0003445308],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015656803,0.000018659053,0.0017546857,0.00003779437,0.0000040523873,0.00021015832,0.00003509731,0.0002475805,0.99353904,0.0005861911,0.000042073574,0.0033680615],"study_design_scores_gemma":[0.00010198215,0.0016046471,0.039856356,0.00007131591,0.000050242896,0.009938864,0.00039784124,0.0035797588,0.9315998,0.00223122,0.010548145,0.000019835543],"about_ca_topic_score_codex":0.00018854254,"about_ca_topic_score_gemma":0.00031027547,"teacher_disagreement_score":0.0012615409,"about_ca_system_score_codex":0.00017784633,"about_ca_system_score_gemma":0.00018340189,"threshold_uncertainty_score":0.0042202473},"labels":[],"label_agreement":null},{"id":"W2145808065","doi":"10.1172/jci36245","title":"Deletion of GSK-3β in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":231,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Heart, Lung, and Blood Institute; Paavo Nurmen Säätiö; American Heart Association","keywords":"Hypertrophic cardiomyopathy; Cardiomyopathy; Medicine; Internal medicine; Cancer research; Biology; Heart failure","score_opus":0.06492582164978884,"score_gpt":0.34089918651078366,"score_spread":0.27597336486099483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145808065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979071,0.0023393673,0.0072077136,0.0005813255,0.00017249658,0.00019501922,0.0039369487,0.0013988937,0.005097101],"genre_scores_gemma":[0.9697278,0.0028038558,0.008771427,0.00041056526,0.000073407056,0.00038107735,0.0028197546,0.0006403487,0.014371844],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947935,0.00006536728,0.00008653138,0.00015776165,0.0001117983,0.0000993207],"domain_scores_gemma":[0.99897814,0.00014738362,0.0004770445,0.00006956486,0.000025384656,0.00030252113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004043722,0.0016724486,0.00042933223,0.0018291806,0.00044457082,0.0006670363,0.0006890636,0.0011680301,0.0066193733],"category_scores_gemma":[0.00029775116,0.0012810437,0.00075319165,0.00047206949,0.0010592837,0.0004184958,0.00056315283,0.0019550975,0.0021209437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033854603,0.0000957753,0.00041086887,0.000064053354,0.000024662077,0.00054643827,0.0000485168,0.00017005624,0.9964948,0.00034921005,0.00013787711,0.0013190667],"study_design_scores_gemma":[0.0006052072,0.0014184592,0.020569833,0.00016229667,0.00013867309,0.004778996,0.000206852,0.0033965483,0.96150005,0.00069306337,0.0064852894,0.0000447709],"about_ca_topic_score_codex":0.0009091907,"about_ca_topic_score_gemma":0.0017482684,"teacher_disagreement_score":0.0066193733,"about_ca_system_score_codex":0.000646669,"about_ca_system_score_gemma":0.0005603872,"threshold_uncertainty_score":0.02214396},"labels":[],"label_agreement":null},{"id":"W2146136895","doi":"10.1172/jci14060","title":"Human sex hormone–binding globulin variants associated with hyperandrogenism and ovarian dysfunction","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; Western University","funders":"Canadian Institutes of Health Research; Fondation de France","keywords":"Sex hormone-binding globulin; Hyperandrogenism; Endocrinology; Internal medicine; Biology; Polycystic ovary; Proband; Androgen; Medicine; Mutation; Genetics; Insulin; Hormone; Gene; Insulin resistance","score_opus":0.10517156090991676,"score_gpt":0.338584032913545,"score_spread":0.23341247200362825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146136895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984909,0.0004917824,0.00020092235,0.000090150905,0.000013575413,0.000009401692,0.000079502075,0.000009480665,0.000614135],"genre_scores_gemma":[0.99915457,0.00016683243,0.00019207754,0.000053646898,0.000031087253,0.0000033726285,0.00007947734,0.000004081176,0.00031481925],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998049,0.000048360398,0.000022926159,0.000042478205,0.00004576043,0.00003562514],"domain_scores_gemma":[0.9995945,0.00013714582,0.00013611723,0.000022250193,0.000026544012,0.00008349135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001685751,0.0006498506,0.00027173146,0.0008119727,0.00036682485,0.00024903205,0.00016166338,0.00059953274,0.0016535288],"category_scores_gemma":[0.00088313845,0.00014892225,0.00020418056,0.0005839468,0.00050922105,0.000120381424,0.00023773362,0.00028298487,0.00018453824],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018720502,0.0002031292,0.61405414,0.0001731676,0.00025829425,0.2199462,0.0013041015,0.00041223102,0.1332469,0.00090672274,0.0010157618,0.026607396],"study_design_scores_gemma":[0.000103164304,0.0005647234,0.6037992,0.00003238043,0.00013276318,0.37916127,0.0002484194,0.00036690492,0.012069981,0.00057794346,0.0029211312,0.000022221213],"about_ca_topic_score_codex":0.0010184151,"about_ca_topic_score_gemma":0.0011212854,"teacher_disagreement_score":0.0016535288,"about_ca_system_score_codex":0.00016622919,"about_ca_system_score_gemma":0.00018823252,"threshold_uncertainty_score":0.005531609},"labels":[],"label_agreement":null},{"id":"W2146764867","doi":"10.1172/jci64551","title":"The TGR5 receptor mediates bile acid–induced itch and analgesia","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":374,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Health and Medical Research Council; Monash University; U.S. Public Health Service; European Regional Development Fund; Regione Toscana; National Science Foundation; Istituto Italiano di Tecnologia; British Heart Foundation; Northern California Institute for Research and Education; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institutes of Health","keywords":"G protein-coupled bile acid receptor; Agonist; Medicine; Pharmacology; Bile acid; Receptor; Stimulation; Cholecystokinin; Cholestasis; Chemistry; Internal medicine; Endocrinology","score_opus":0.05786368543612671,"score_gpt":0.34501343797492023,"score_spread":0.28714975253879355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146764867","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98082787,0.012655625,0.0021264001,0.0005963787,0.00007155865,0.00006903895,0.0001925673,0.000098274795,0.0033623092],"genre_scores_gemma":[0.9965959,0.0018420881,0.00045768486,0.00015282613,0.000027543552,0.000016392449,0.00012376202,0.0000036624633,0.0007800479],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998714,0.000038683695,0.00001171838,0.000017134578,0.00001551566,0.000045623543],"domain_scores_gemma":[0.9999217,0.000007875912,0.000029574034,0.0000075020434,0.000008399543,0.000025033201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017001467,0.00034143566,0.00031949222,0.0001480461,0.00012413584,0.00022967243,0.00014693018,0.00040298107,0.0014969768],"category_scores_gemma":[0.00015881208,0.000089356574,0.00047299598,0.000073701805,0.00026994201,0.00020439384,0.00023678286,0.0004746513,0.00042216046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023840163,0.00018400101,0.012247563,0.00049996126,0.00010561281,0.0028316593,0.00012664983,0.000248546,0.9580066,0.00061357336,0.00091615086,0.02183552],"study_design_scores_gemma":[0.0007979257,0.011298014,0.4583443,0.0003824457,0.00063006725,0.017488064,0.0011483403,0.0056235236,0.47937182,0.00082109246,0.024024237,0.00007017579],"about_ca_topic_score_codex":0.00039157955,"about_ca_topic_score_gemma":0.00059767533,"teacher_disagreement_score":0.0014969768,"about_ca_system_score_codex":0.00021141717,"about_ca_system_score_gemma":0.00012003194,"threshold_uncertainty_score":0.005007863},"labels":[],"label_agreement":null},{"id":"W2147779090","doi":"10.1172/jci13171","title":"Accelerated apoptosis in the Timp-3–deficient mammary gland","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Muscular Dystrophy Canada; Ontario Institute for Cancer Research; University of Toronto","funders":"Medical Research and Materiel Command; Canadian Institutes of Health Research; U.S. Army; University of Toronto","keywords":"Involution (esoterism); Mammary gland; Internal medicine; Endocrinology; Apoptosis; Biology; Lactation; Epithelium; Adipose tissue; Programmed cell death; Medicine","score_opus":0.07623519592758732,"score_gpt":0.3524158687825455,"score_spread":0.2761806728549582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147779090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955193,0.0015844855,0.0016576516,0.000096072334,0.000024967616,0.000024148334,0.00038657602,0.00012556679,0.0005812468],"genre_scores_gemma":[0.99466926,0.00092752924,0.0016315263,0.0000692174,0.000012108908,0.00003595821,0.0004743414,0.000026282161,0.0021537791],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985397,0.00002015476,0.000015632515,0.000027138425,0.000048130278,0.00003492761],"domain_scores_gemma":[0.9998086,0.000022527021,0.00007480482,0.000022231432,0.000015063026,0.000056821787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017120973,0.00032007392,0.00031672698,0.00033998955,0.00013163718,0.000360872,0.00016194912,0.0003675002,0.0012926974],"category_scores_gemma":[0.00015024887,0.00017006122,0.00033453555,0.00017671667,0.00025504167,0.00019451413,0.0001777126,0.0008892984,0.0004096313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018899869,0.000014218958,0.00032010893,0.000014816133,0.0000026836751,0.00011123212,0.000009431864,0.000014750731,0.9987173,0.000022590248,0.000016692084,0.000567184],"study_design_scores_gemma":[0.000046141056,0.00078564254,0.01603404,0.000008260778,0.000022938795,0.0025749407,0.000043488566,0.00068032695,0.977992,0.00008788141,0.0017169162,0.000007307067],"about_ca_topic_score_codex":0.00033261473,"about_ca_topic_score_gemma":0.0005912506,"teacher_disagreement_score":0.0012926974,"about_ca_system_score_codex":0.00036827457,"about_ca_system_score_gemma":0.00022444697,"threshold_uncertainty_score":0.0043245554},"labels":[],"label_agreement":null},{"id":"W2147888714","doi":"10.1172/jci43910","title":"Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; Fondation Leducq; Howard Hughes Medical Institute","keywords":"Noonan syndrome; Guanine nucleotide exchange factor; Mutation; Biology; Mutant; Phenotype; Signal transduction; Genetics; MAPK/ERK pathway; Cancer research; Costello syndrome; Positional cloning; Cell biology; Gene; KRAS","score_opus":0.039485926870494736,"score_gpt":0.298727465877662,"score_spread":0.2592415390071673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147888714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99515945,0.00046493026,0.0017426781,0.0002158239,0.00003760729,0.000040168514,0.00072815496,0.00015821532,0.0014529319],"genre_scores_gemma":[0.98993623,0.0008153937,0.003411814,0.00011283042,0.000020924243,0.00009248803,0.0006865321,0.000072574476,0.004851277],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995741,0.000076738426,0.000053785992,0.00010584542,0.000114956594,0.00007461992],"domain_scores_gemma":[0.99961025,0.00006693321,0.00012186381,0.000021209678,0.000013990293,0.00016583153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002866056,0.001158866,0.00031431657,0.0011008903,0.00030670298,0.00038274445,0.0004064082,0.00069365767,0.0026502397],"category_scores_gemma":[0.00024132551,0.0005180012,0.00045046044,0.00020830969,0.0006916285,0.00026816074,0.00044281097,0.00096037256,0.00054520206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044722584,0.00014172046,0.00070330995,0.000041288975,0.000015034625,0.00073354365,0.00005257598,0.0001894002,0.99550533,0.00039336417,0.00013104825,0.001646046],"study_design_scores_gemma":[0.00047974824,0.0017594763,0.025509782,0.000092504895,0.00012837302,0.0057990365,0.0002146545,0.007829286,0.95001817,0.0007163812,0.0074046026,0.000047946396],"about_ca_topic_score_codex":0.00093890104,"about_ca_topic_score_gemma":0.0021774834,"teacher_disagreement_score":0.0026502397,"about_ca_system_score_codex":0.00046887257,"about_ca_system_score_gemma":0.00034628066,"threshold_uncertainty_score":0.008865893},"labels":[],"label_agreement":null},{"id":"W2148418288","doi":"10.1172/jci15883","title":"EphB6 crosslinking results in costimulation of T cells","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Roche Organ Transplant Research Foundation; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"CD28; T cell; Biology; T-cell receptor; Cell biology; Immunology; Immune system","score_opus":0.27908655831452694,"score_gpt":0.4060633871174051,"score_spread":0.12697682880287814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148418288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98934877,0.0023679275,0.0018803914,0.00018857727,0.0001504984,0.00007633,0.00042588948,0.00013307326,0.0054284805],"genre_scores_gemma":[0.99016833,0.00090436003,0.0024069268,0.00018570432,0.00006973596,0.00009199969,0.00080963323,0.00003875624,0.0053245085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954516,0.00008386276,0.000035132533,0.000080553946,0.00009562033,0.00015969896],"domain_scores_gemma":[0.99980444,0.000051461684,0.000024823308,0.00002686939,0.000013330354,0.00007908461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015761216,0.00057549693,0.00029885775,0.00016714787,0.00012412685,0.00029443455,0.00016580669,0.0003814153,0.0031366528],"category_scores_gemma":[0.00015745143,0.00016628721,0.0002702915,0.00014775193,0.00010810666,0.00021975298,0.0003429114,0.0010060703,0.0012270269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033226536,0.00008864082,0.000102191276,0.000046019155,0.000008003034,0.00011856318,0.000015615207,0.00007903066,0.9970188,0.000105309664,0.00015247308,0.0019331066],"study_design_scores_gemma":[0.0000594737,0.0005865325,0.0034796153,0.00000903982,0.000023392877,0.0007155613,0.000012769776,0.0009003599,0.9882002,0.000054504202,0.0059542884,0.0000042018546],"about_ca_topic_score_codex":0.00016308732,"about_ca_topic_score_gemma":0.00023914402,"teacher_disagreement_score":0.0031366528,"about_ca_system_score_codex":0.00024115597,"about_ca_system_score_gemma":0.00013927279,"threshold_uncertainty_score":0.010493159},"labels":[],"label_agreement":null},{"id":"W2149075421","doi":"10.1172/jci19711","title":"Antigen-specific CD4+ T cells drive airway smooth muscle remodeling in experimental asthma","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Christie (Canada)","funders":"Canadian Institutes of Health Research; European Respiratory Society; McGill University; GlaxoSmithKline; Lady Davis Institute for Medical Research; Canadian Lung Association; AstraZeneca","keywords":"Asthma; Antigen; Immunology; Airway; Medicine; Anesthesia","score_opus":0.06677688969783094,"score_gpt":0.36745949303800607,"score_spread":0.30068260334017516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149075421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963253,0.0010886212,0.00097624457,0.00023979707,0.000060509177,0.00006111068,0.00008758902,0.00010000376,0.0010608865],"genre_scores_gemma":[0.99359703,0.000948165,0.0024453567,0.00015134066,0.000075167896,0.00013457192,0.00020636673,0.000024161494,0.0024176636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994717,0.00013710269,0.000057021534,0.00007887341,0.0001201549,0.00013509495],"domain_scores_gemma":[0.9998185,0.000028415036,0.000038714275,0.00002513822,0.000016814622,0.00007243637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036530886,0.000608692,0.00043267646,0.00049780984,0.00029580283,0.00039734828,0.00026529504,0.00066769455,0.001602468],"category_scores_gemma":[0.00024821708,0.0003089793,0.00029229687,0.00015568132,0.00051843614,0.00034008987,0.00029533388,0.0019053875,0.00049417414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003649208,0.00032691268,0.0003205529,0.000054074015,0.0000046464056,0.0000951214,0.000020970301,0.00007733949,0.9964819,0.00010027009,0.000057190617,0.0020961075],"study_design_scores_gemma":[0.00035808588,0.0035786654,0.006766312,0.000021026413,0.000043464654,0.00054160366,0.00007659609,0.0018200491,0.9844744,0.00020001695,0.0021117015,0.0000081940325],"about_ca_topic_score_codex":0.00029976148,"about_ca_topic_score_gemma":0.00053087727,"teacher_disagreement_score":0.001602468,"about_ca_system_score_codex":0.00044131879,"about_ca_system_score_gemma":0.0002303347,"threshold_uncertainty_score":0.005360782},"labels":[],"label_agreement":null},{"id":"W2149268046","doi":"10.1172/jci59211","title":"Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"National Institute on Drug Abuse; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Genome Canada","keywords":"Gene silencing; Immunology; Apoptosis; Immune system; Biology; Cancer research; Medicine; Genetics; Gene","score_opus":0.03891366200977273,"score_gpt":0.29033349792038343,"score_spread":0.2514198359106107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149268046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99868184,0.0006755569,0.0003105393,0.000021624592,0.0000041125804,0.000005308125,0.00003992957,0.000011232361,0.00024972603],"genre_scores_gemma":[0.9990263,0.0002188006,0.00023285764,0.000017385024,0.0000051633006,0.000007970641,0.000068290276,0.00000342562,0.00041985867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990964,0.000014182719,0.000008194617,0.000020546404,0.000017873852,0.000029533823],"domain_scores_gemma":[0.99990034,0.000009368675,0.000043440992,0.000012194144,0.000011696188,0.000023050994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016095047,0.00018828078,0.00021102205,0.00021947386,0.00018260675,0.00023999855,0.0001008975,0.00021073432,0.00095206563],"category_scores_gemma":[0.00011401741,0.00015771724,0.00016226675,0.00011213771,0.00029431836,0.00013302063,0.00019592674,0.00039415382,0.00017119716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046049093,0.00005404704,0.0043142713,0.000027373126,0.000009362152,0.00009798879,0.000050572624,0.00002662343,0.99139434,0.000050481452,0.00003494345,0.0034796],"study_design_scores_gemma":[0.00018377433,0.003509834,0.26256526,0.00003736676,0.000096796844,0.003290915,0.00025350254,0.0011503721,0.72585565,0.00038863457,0.0026518314,0.000016007976],"about_ca_topic_score_codex":0.0003891998,"about_ca_topic_score_gemma":0.00059345557,"teacher_disagreement_score":0.00095206563,"about_ca_system_score_codex":0.00014698344,"about_ca_system_score_gemma":0.00012244482,"threshold_uncertainty_score":0.0031849742},"labels":[],"label_agreement":null},{"id":"W2149526310","doi":"10.1172/jci21686","title":"Rescue of retinal degeneration by intravitreally injected adult bone marrow–derived lineage-negative hematopoietic stem cells","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":307,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; University of California, San Diego; University of British Columbia","keywords":"Retinal degeneration; Retinal; Biology; Retina; Haematopoiesis; Stem cell; Macular degeneration; Bone marrow; Pathology; Cell biology; Anatomy; Neuroscience; Immunology; Medicine; Ophthalmology","score_opus":0.020181582217655994,"score_gpt":0.2911737099127938,"score_spread":0.2709921276951378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149526310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99399334,0.0019656972,0.0018936412,0.00015540299,0.00004567624,0.00005362912,0.00027280374,0.0001905178,0.0014294266],"genre_scores_gemma":[0.990346,0.0011560888,0.0028699506,0.00010718644,0.000025714024,0.0000668822,0.0008117563,0.000026912829,0.0045895255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987686,0.00002409629,0.000011716813,0.000025210924,0.000034318484,0.000027802243],"domain_scores_gemma":[0.99992454,0.000011323296,0.00001759397,0.000009884667,0.0000076794,0.000029029967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017669256,0.00032439255,0.00023844486,0.00023458987,0.0001162502,0.00024335324,0.00017490152,0.00026541724,0.0013453068],"category_scores_gemma":[0.00008738009,0.00008974992,0.00013416147,0.00007657033,0.00022192048,0.00008722375,0.000116558884,0.00075426337,0.00026952257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014141518,0.00012624088,0.00021854801,0.000036517184,0.000006822988,0.000075837735,0.000019594747,0.000028522454,0.9959125,0.000078207784,0.00012346267,0.003232366],"study_design_scores_gemma":[0.00009033458,0.0022782837,0.0061705466,0.000018406903,0.00003727471,0.00052832183,0.000051735267,0.00078076514,0.9856309,0.000055836026,0.0043537864,0.0000038046135],"about_ca_topic_score_codex":0.00038067557,"about_ca_topic_score_gemma":0.0009694665,"teacher_disagreement_score":0.0013453068,"about_ca_system_score_codex":0.00012222737,"about_ca_system_score_gemma":0.00019691145,"threshold_uncertainty_score":0.0045005083},"labels":[],"label_agreement":null},{"id":"W2149529721","doi":"10.1172/jci72241","title":"Prion disease tempo determined by host-dependent substrate reduction","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; Alberta Prion Research Institute; Centers for Disease Control and Prevention; U.S. Public Health Service; Canadian Institutes of Health Research; Alberta Innovates; Cleveland Clinic","keywords":"Downregulation and upregulation; Scrapie; Biology; Pathogenesis; Glycoprotein; Virology; Glycosylation; Chronic wasting disease; In vitro; Disease; Cell biology; Prion protein; Immunology; Molecular biology; Genetics; Gene; Medicine; Pathology","score_opus":0.03350529041783667,"score_gpt":0.3366516527672306,"score_spread":0.3031463623493939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149529721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98984796,0.0028652756,0.0024882779,0.000072148716,0.000044920598,0.00005335827,0.00041480846,0.00015878631,0.0040544816],"genre_scores_gemma":[0.99549747,0.0008922299,0.0008657898,0.000045145196,0.000016346452,0.000028015362,0.00036369512,0.000020754544,0.002270511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999851,0.000021409682,0.000014919791,0.000050845687,0.000036690733,0.000025171497],"domain_scores_gemma":[0.9998288,0.000023121776,0.00005006507,0.000026641848,0.000030782277,0.000040640243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002014979,0.00022739933,0.00020177936,0.00030307772,0.0001295426,0.00044464864,0.0001440571,0.00019571948,0.0017795948],"category_scores_gemma":[0.00020969588,0.00013126628,0.00009976465,0.00012332248,0.00020558925,0.0002939479,0.00023392898,0.00036729444,0.0005516202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014595817,0.000031908832,0.0012603152,0.000019083367,0.000004101481,0.000082593004,0.000017197868,0.000013897672,0.99639505,0.00015037623,0.000068230955,0.0018111735],"study_design_scores_gemma":[0.000020420035,0.0012549007,0.08452587,0.000017880926,0.000028032788,0.0022276635,0.00007975965,0.0011689606,0.90472674,0.00041581475,0.0055187573,0.000015257713],"about_ca_topic_score_codex":0.00021405892,"about_ca_topic_score_gemma":0.0002899703,"teacher_disagreement_score":0.0017795948,"about_ca_system_score_codex":0.00016200177,"about_ca_system_score_gemma":0.000107415304,"threshold_uncertainty_score":0.005953312},"labels":[],"label_agreement":null},{"id":"W2149545030","doi":"10.1172/jci7456","title":"Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":168,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"American Diabetes Association; Medical Research Council; Medical Research Council Canada; Cedars-Sinai Medical Center; National Institute on Drug Abuse; Canadian Diabetes Association","keywords":"Proglucagon; Glucagon; Internal medicine; Endocrinology; Proinsulin; Insulin; Streptozotocin; Prohormone; Pancreas; Glucagon-like peptide-1; Pancreatic polypeptide; Islet; Prohormone convertase; Pancreatic hormone; Biology; Chemistry; Diabetes mellitus; Medicine; Hormone; Type 2 diabetes; Insulin resistance","score_opus":0.03856143132473881,"score_gpt":0.3108096892421192,"score_spread":0.2722482579173804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149545030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980951,0.0006005584,0.0005915059,0.00004754731,0.000017824477,0.0000131577945,0.00017181231,0.000053243708,0.00040925396],"genre_scores_gemma":[0.99301857,0.0012000996,0.0015379282,0.00011901637,0.00002418564,0.000062842584,0.00072926364,0.000044417815,0.0032637385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999833,0.000015185171,0.000014266644,0.000047980644,0.000043723885,0.000045827222],"domain_scores_gemma":[0.9995958,0.000020899177,0.00014499464,0.00002731601,0.000048888556,0.00016215477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013144113,0.0007549677,0.0004947362,0.0010991278,0.0002278412,0.0004526027,0.0001654709,0.00033705254,0.0013839495],"category_scores_gemma":[0.0001688151,0.0003515346,0.00038430217,0.00046332556,0.00039706868,0.00025158704,0.00020055065,0.0009243314,0.00021709832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001067779,0.000065954446,0.001098833,0.00003310586,0.000013121317,0.00011041899,0.000016577978,0.00002721568,0.99604213,0.000030009796,0.000031634332,0.0014631223],"study_design_scores_gemma":[0.00015911473,0.0018398854,0.118215166,0.000011790604,0.00010056432,0.00074741215,0.00010921142,0.0007406077,0.8767154,0.00009367807,0.0012430378,0.000024115167],"about_ca_topic_score_codex":0.0014897104,"about_ca_topic_score_gemma":0.00160981,"teacher_disagreement_score":0.0014897104,"about_ca_system_score_codex":0.0005320518,"about_ca_system_score_gemma":0.00029931284,"threshold_uncertainty_score":0.004629791},"labels":[],"label_agreement":null},{"id":"W2149578816","doi":"10.1172/jci24186","title":"Lack of MEF2A mutations in coronary artery disease","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"Joint Genome Institute; Canadian Institutes of Health Research; Lawrence Berkeley National Laboratory; University of Ottawa; Heart and Stroke Foundation of Canada; U.S. Department of Energy","keywords":"Proband; Coronary artery disease; Genetics; CAD; Genotyping; Mutation; Coding region; Biology; Medicine; Internal medicine; Genotype; Gene","score_opus":0.20520920108308602,"score_gpt":0.4549021402352849,"score_spread":0.2496929391521989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149578816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99798965,0.0007243549,0.00026574783,0.000059696995,0.00001143166,0.0000036332008,0.000083134226,0.000012214446,0.0008499803],"genre_scores_gemma":[0.9993075,0.00014361592,0.00012933539,0.000034935427,0.000016237467,0.0000025807335,0.00009150712,0.000004213163,0.0002700699],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99983954,0.000026450061,0.000025355737,0.00004397542,0.000042239637,0.000022481854],"domain_scores_gemma":[0.99960166,0.00013177497,0.000082661885,0.000034704663,0.000047921032,0.000101252896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027778745,0.00023121727,0.00026237438,0.00057099154,0.00023461875,0.00022748607,0.00017231784,0.00036981396,0.0022808956],"category_scores_gemma":[0.0012169379,0.00012551429,0.00008664825,0.00016286386,0.00029890906,0.00019440103,0.0002047711,0.00018324984,0.0003340766],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014515271,0.00035179086,0.59351873,0.00015880034,0.00014197569,0.022539409,0.0005637886,0.00019186697,0.3510244,0.0011947374,0.001169885,0.027693111],"study_design_scores_gemma":[0.000105919964,0.00055509846,0.88870245,0.000050634604,0.00010166464,0.090224616,0.00018719205,0.00072444417,0.013974459,0.0009972372,0.0043574376,0.000018752016],"about_ca_topic_score_codex":0.00041157415,"about_ca_topic_score_gemma":0.0004942243,"teacher_disagreement_score":0.0022808956,"about_ca_system_score_codex":0.00008292228,"about_ca_system_score_gemma":0.00008054025,"threshold_uncertainty_score":0.007630348},"labels":[],"label_agreement":null},{"id":"W2149694801","doi":"10.1172/jci43737","title":"Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital gastrointestinal and neural anomalies","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; University of Hong Kong","keywords":"Gliogenesis; Biology; Notch signaling pathway; Hedgehog; Patched; PTCH1; GLI2; Neural crest; Smoothened; Decussation; Enteric nervous system; Neuroscience; Hedgehog signaling pathway; Neurogenesis; Genetics; Cell biology; Neural stem cell; Signal transduction; Stem cell; Gene","score_opus":0.17134355207433016,"score_gpt":0.36753075080787856,"score_spread":0.1961871987335484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149694801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9806842,0.010864966,0.0039136056,0.0005987422,0.00005443399,0.00005227223,0.0005537098,0.00019098446,0.003087025],"genre_scores_gemma":[0.99060494,0.004045485,0.0032752103,0.00033404893,0.00004921183,0.000031418804,0.00053716236,0.000016859458,0.0011056677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998523,0.000038287384,0.000015267828,0.000043412732,0.000036601665,0.000014079823],"domain_scores_gemma":[0.9999236,0.000011707822,0.00002699277,0.00001090099,0.000005799264,0.000021048972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026717313,0.00038234147,0.0003458163,0.0003994617,0.00012355518,0.0003703769,0.00017475749,0.0002648904,0.00088145584],"category_scores_gemma":[0.00020833591,0.00012643238,0.00020459291,0.0003121512,0.00030353892,0.00020925487,0.00029340977,0.0003635797,0.00011833518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032431106,0.00025749116,0.15034069,0.0005879984,0.00043785849,0.011236588,0.000237724,0.00044883875,0.7286885,0.00490044,0.002144126,0.09747657],"study_design_scores_gemma":[0.00039626998,0.0026742727,0.7933023,0.0002346273,0.0007772923,0.046293695,0.00034034826,0.0047403043,0.113663346,0.0029548786,0.034562428,0.00006022998],"about_ca_topic_score_codex":0.0003162864,"about_ca_topic_score_gemma":0.00041270824,"teacher_disagreement_score":0.00088145584,"about_ca_system_score_codex":0.00021518029,"about_ca_system_score_gemma":0.0002260448,"threshold_uncertainty_score":0.002948761},"labels":[],"label_agreement":null},{"id":"W2150105325","doi":"10.1172/jci18589","title":"A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interaction","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Medical Research Council; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo; Wellcome Trust","keywords":"Biology; Hypopituitarism; Haploinsufficiency; Genetics; Forebrain; Corepressor; Endocrinology; Repressor; Phenotype; Gene; Transcription factor","score_opus":0.06938387433390723,"score_gpt":0.3538282214987097,"score_spread":0.28444434716480244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150105325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99729186,0.00023396125,0.00086139294,0.00008915808,0.000022734497,0.000022412445,0.00028725242,0.00012668196,0.0010645298],"genre_scores_gemma":[0.99733186,0.00018282261,0.00049815606,0.00003145062,0.000027054251,0.000009050379,0.00019342944,0.00002941131,0.0016966809],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99982494,0.000013985627,0.000022456861,0.00006583892,0.000043756907,0.000029086625],"domain_scores_gemma":[0.9997532,0.000057429053,0.000086989276,0.00001547275,0.000007694753,0.000079143785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012956707,0.0012868452,0.0003981812,0.0008163949,0.0003392853,0.0002441511,0.00047718495,0.0008211014,0.0031452375],"category_scores_gemma":[0.00032601654,0.00028101198,0.0003094368,0.00042321853,0.0008657788,0.00022099057,0.0005428205,0.0005221972,0.00050107396],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064281694,0.00015421875,0.016534418,0.00016137422,0.00011724202,0.43203223,0.00045632216,0.00036102647,0.5392987,0.001000592,0.0005156723,0.00872528],"study_design_scores_gemma":[0.000104745595,0.00084680447,0.107771255,0.00002975202,0.00011353881,0.79150635,0.0001864959,0.0013126538,0.09360267,0.00035335662,0.0041164253,0.000055921457],"about_ca_topic_score_codex":0.0006532002,"about_ca_topic_score_gemma":0.00064801157,"teacher_disagreement_score":0.0031452375,"about_ca_system_score_codex":0.00026569728,"about_ca_system_score_gemma":0.00020709848,"threshold_uncertainty_score":0.010521889},"labels":[],"label_agreement":null},{"id":"W2150240056","doi":"10.1172/jci40115","title":"Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":401,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Yerkes National Primate Research Center, Emory University; National Institutes of Health; Canadian Institutes of Health Research; Li Ka Shing Foundation; Center for AIDS Research, University of Washington; Emory University; University of Pennsylvania","keywords":"Innate immune system; Immune system; Biology; Immunology; Simian immunodeficiency virus; Immunity; Downregulation and upregulation; Phenotype; Virology; Gene; Genetics","score_opus":0.05874832140545877,"score_gpt":0.3811057037450673,"score_spread":0.32235738233960853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150240056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99903226,0.00013026939,0.00037094357,0.000010168506,0.000002246202,0.0000038855073,0.0002743284,0.000014519114,0.0001613638],"genre_scores_gemma":[0.99799526,0.00007940049,0.00072058284,0.00003152411,0.0000042936967,0.00001917772,0.00064805994,0.000010040183,0.0004917005],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999336,0.000005064538,0.00000353374,0.000030317211,0.00001031745,0.000017038004],"domain_scores_gemma":[0.99988616,0.000020660671,0.00003944544,0.000013045915,0.0000123007,0.00002834691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006962932,0.00016204613,0.000211445,0.0002913195,0.00016411237,0.00026511602,0.00007855638,0.00017220927,0.0005721456],"category_scores_gemma":[0.00011153231,0.00012096621,0.00014924322,0.00011766143,0.00026750244,0.00010843797,0.00015682093,0.0002505004,0.00014788838],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047111535,0.0000034633417,0.0018861865,0.000010314308,0.0000028130198,0.000016603364,0.000025801011,0.000019836521,0.9977043,0.000018346098,0.000006671006,0.00025851416],"study_design_scores_gemma":[0.000014248143,0.000860506,0.6826736,0.0000141007995,0.00005550604,0.0005665926,0.00044908276,0.0014489824,0.31182238,0.00021079644,0.0018622576,0.000022059286],"about_ca_topic_score_codex":0.0006589021,"about_ca_topic_score_gemma":0.0012281869,"teacher_disagreement_score":0.0006589021,"about_ca_system_score_codex":0.00015867449,"about_ca_system_score_gemma":0.00008515676,"threshold_uncertainty_score":0.0019140244},"labels":[],"label_agreement":null},{"id":"W2150472993","doi":"10.1172/jci57256","title":"An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":824,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; Simon Fraser University","funders":"Canadian Institutes of Health Research; Universidade Federal do Rio de Janeiro; National Institute on Aging; Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; T.L.L Temple Foundation; National Institutes of Health; John Simon Guggenheim Memorial Foundation; American Health Assistance Foundation; Alzheimer's Association","keywords":"Hippocampal formation; Insulin receptor; Phosphorylation; Endocrinology; Insulin resistance; Insulin; Diabetes mellitus; Internal medicine; Signal transduction; Hippocampus; Neuroscience; Medicine; Chemistry; Biology; Cell biology","score_opus":0.09846863438673782,"score_gpt":0.38965359070762073,"score_spread":0.2911849563208829,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150472993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921795,0.002123547,0.0019258172,0.00021988226,0.00013404305,0.00007471698,0.00096677593,0.000276961,0.002098823],"genre_scores_gemma":[0.9812262,0.0034543653,0.0041446947,0.00025476416,0.00004780399,0.00021029526,0.0026667567,0.000065872875,0.007929164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984384,0.000014855199,0.000023376037,0.00003992475,0.000032903867,0.00004508789],"domain_scores_gemma":[0.99982953,0.000016772541,0.000046865527,0.00002457636,0.000022210155,0.000060052065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019716396,0.00093719986,0.00043864732,0.0007407385,0.00028538294,0.00034281777,0.00051219395,0.0005995296,0.0023057086],"category_scores_gemma":[0.00011138182,0.00032842392,0.00050933345,0.00028397134,0.0002745578,0.00033589633,0.00017488752,0.0015826749,0.00059215375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010409248,0.0005570853,0.00018728196,0.000070148264,0.00002626622,0.000075631666,0.000022218055,0.000047080946,0.9955449,0.00010898337,0.00008661056,0.002232933],"study_design_scores_gemma":[0.00024486257,0.0031950863,0.0060710656,0.000033567023,0.00005969651,0.00030163053,0.000029702116,0.0006608671,0.986334,0.00014016865,0.0029170173,0.000012245511],"about_ca_topic_score_codex":0.0005909134,"about_ca_topic_score_gemma":0.0008439911,"teacher_disagreement_score":0.0023057086,"about_ca_system_score_codex":0.0002779647,"about_ca_system_score_gemma":0.00033093424,"threshold_uncertainty_score":0.0077133775},"labels":[],"label_agreement":null},{"id":"W2150893441","doi":"10.1172/jci17423","title":"Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":1278,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; St. Michael's Hospital; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Kidney Foundation of Canada","keywords":"Podocyte; Glomerulus; Kidney disease; Kidney; Renal function; Biology; Pathology; Glomerulopathy; Glomerulonephritis; Endocrinology; Internal medicine; Proteinuria; Medicine","score_opus":0.06626429097389486,"score_gpt":0.3621689072289696,"score_spread":0.29590461625507475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150893441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968406,0.0008821011,0.0011800379,0.00006178942,0.000010736756,0.000006841824,0.00009619976,0.000041679672,0.00088001654],"genre_scores_gemma":[0.99878484,0.00037221922,0.00041323566,0.000022699367,0.000005890556,0.0000034392062,0.000067805806,0.0000052732103,0.00032463865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989676,0.000021067786,0.00000960794,0.000028346101,0.000023228733,0.000020894648],"domain_scores_gemma":[0.999894,0.000015663793,0.000036783404,0.000006762056,0.000008403693,0.000038236434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001453741,0.00023782499,0.00013439181,0.00024726047,0.000110360954,0.00015164718,0.000100997226,0.0001998394,0.00151674],"category_scores_gemma":[0.00024292205,0.000083491504,0.00011360545,0.00011348851,0.00025919013,0.00009666767,0.00020957734,0.00028052533,0.00012735839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039090647,0.000104996056,0.015245123,0.000085136955,0.000032789212,0.004664293,0.00006370683,0.0001551328,0.9685365,0.0009586521,0.00020750672,0.009555159],"study_design_scores_gemma":[0.00014082246,0.0017020362,0.42745042,0.000044036824,0.00015913606,0.09436338,0.00018750077,0.0017271652,0.46688512,0.0010003108,0.0063156206,0.0000245172],"about_ca_topic_score_codex":0.00031459928,"about_ca_topic_score_gemma":0.00040929642,"teacher_disagreement_score":0.00151674,"about_ca_system_score_codex":0.0001680644,"about_ca_system_score_gemma":0.00015677234,"threshold_uncertainty_score":0.0050739646},"labels":[],"label_agreement":null},{"id":"W2151753166","doi":"10.1172/jci18784","title":"Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":296,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; National Institutes of Health; Ipsen; Vlaamse regering; Wellcome Trust","keywords":"Endocrinology; Internal medicine; Missense mutation; Nonsense mutation; Allele; Biology; Medicine; Phenotype; Genetics; Gene","score_opus":0.16691108186061038,"score_gpt":0.3650470267147205,"score_spread":0.19813594485411012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151753166","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969703,0.0011302625,0.00039719656,0.00007025962,0.000014386514,0.000034632652,0.00013458294,0.000045060257,0.0012033246],"genre_scores_gemma":[0.998643,0.00047471418,0.00040415,0.00004465474,0.00003853979,0.0000082936385,0.000086145956,0.000009660139,0.00029077867],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.99978584,0.000029010305,0.000033520577,0.000067516616,0.000039525643,0.000044592154],"domain_scores_gemma":[0.99935156,0.0001933478,0.00019907785,0.000046816418,0.000025954583,0.00018317957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023017026,0.0016730266,0.0006757118,0.0015699489,0.00055330526,0.00055066484,0.00037370957,0.0010924699,0.0017122135],"category_scores_gemma":[0.0009933496,0.00060535147,0.00034199466,0.00074598385,0.0008927678,0.0003162656,0.00063197094,0.00051186234,0.00036684406],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014263625,0.000107265325,0.14799507,0.0004367686,0.00016088464,0.7375882,0.0007002159,0.00027196488,0.100982755,0.00026075036,0.00052063726,0.009549115],"study_design_scores_gemma":[0.000099906254,0.000577498,0.22021665,0.00002856311,0.00009199179,0.7631715,0.00018952222,0.00037561508,0.013509268,0.00018681026,0.0015276469,0.00002507231],"about_ca_topic_score_codex":0.0019765894,"about_ca_topic_score_gemma":0.0019803774,"teacher_disagreement_score":0.0019765894,"about_ca_system_score_codex":0.0002538089,"about_ca_system_score_gemma":0.00029719158,"threshold_uncertainty_score":0.005727887},"labels":[],"label_agreement":null},{"id":"W2152064427","doi":"10.1172/jci23002","title":"Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"BC Cancer Agency; Canadian Institutes of Health Research; Canadian Association of Gastroenterology","keywords":"Osteonectin; Colorectal cancer; Irinotecan; Chemotherapy; Cancer research; Cancer; Radiation therapy; Radioresistance; Biology; Medicine; Internal medicine","score_opus":0.1331222086344916,"score_gpt":0.4209273055234882,"score_spread":0.28780509688899664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152064427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968772,0.0011650962,0.0009565429,0.00007531528,0.0000039085294,0.000007280733,0.00041239487,0.00002299737,0.0004792826],"genre_scores_gemma":[0.9960116,0.0007181363,0.0009447487,0.00007505029,0.0000068073914,0.00000942979,0.0011533464,0.00000785734,0.0010730096],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999317,0.000007730663,0.000003129019,0.000020412737,0.000025383551,0.000011647467],"domain_scores_gemma":[0.99995077,0.0000127699095,0.000014045776,0.000004844794,0.0000067530045,0.000010745099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011549423,0.00009924382,0.00024045732,0.00023915226,0.00010766573,0.00028702288,0.00006931094,0.00017098655,0.00076110644],"category_scores_gemma":[0.00010240858,0.00006963271,0.00011803125,0.00022507636,0.000111900794,0.00006504454,0.000073042225,0.00019375149,0.00012724052],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013724575,0.000011449778,0.005820281,0.000021294218,0.000015864061,0.000042110674,0.000015334594,0.000100378194,0.99045044,0.00004351637,0.000071076916,0.0032710135],"study_design_scores_gemma":[0.00003138178,0.0005287334,0.5229452,0.00001215336,0.00015373378,0.001452133,0.00014805075,0.0039859675,0.4621012,0.0002375387,0.00839063,0.000013138184],"about_ca_topic_score_codex":0.00061093434,"about_ca_topic_score_gemma":0.001117361,"teacher_disagreement_score":0.00076110644,"about_ca_system_score_codex":0.00015653006,"about_ca_system_score_gemma":0.000103722385,"threshold_uncertainty_score":0.0025461316},"labels":[],"label_agreement":null},{"id":"W2152791016","doi":"10.1172/jci18236","title":"Transplacental thyroxine and fetal brain development","year":2003,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University; Heart and Stroke Foundation of Canada","keywords":"Thyroid; Hormone; Endocrinology; Offspring; Internal medicine; Medicine; Fetus; Pregnancy; Transplacental; Thyroid function; Biology; Placenta","score_opus":0.15046347556549436,"score_gpt":0.4413786076902749,"score_spread":0.2909151321247806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152791016","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024410446,0.9982437,0.00010006015,0.00014517002,0.00008617666,0.0000023866794,0.000008773428,0.0000056801305,0.0011639643],"genre_scores_gemma":[0.0018066673,0.9967804,0.00013142363,0.00010143116,0.00009601101,0.000005366577,0.000015396345,9.766956e-7,0.0010622637],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99992824,0.000011526274,0.000011500778,0.000017134116,0.000023405471,0.000008345015],"domain_scores_gemma":[0.9998872,0.000050235303,0.000021800699,0.000004591569,0.000022944647,0.000013277837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029532544,0.00057109137,0.000799435,0.0011113161,0.00020709097,0.00062882924,0.00060543284,0.0009433203,0.0033696026],"category_scores_gemma":[0.00027475157,0.00020308318,0.00022257652,0.0010419586,0.0003727537,0.00075136725,0.0003694744,0.0008137612,0.0025669327],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011244266,0.000050327286,0.000320691,0.0058411667,0.000039883984,0.00085207395,0.00005337474,0.0002154139,0.0059432043,0.0023127769,0.011651286,0.97260743],"study_design_scores_gemma":[0.00003330895,0.0001795219,0.0027127857,0.0014271829,0.00008410268,0.005177859,0.0001162601,0.00009266084,0.002934733,0.0025368792,0.9846846,0.000020193074],"about_ca_topic_score_codex":0.0014648394,"about_ca_topic_score_gemma":0.0028824103,"teacher_disagreement_score":0.0033696026,"about_ca_system_score_codex":0.00064767076,"about_ca_system_score_gemma":0.0007419452,"threshold_uncertainty_score":0.01127243},"labels":[],"label_agreement":null},{"id":"W2153081066","doi":"10.1172/jci60433","title":"Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":974,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montfort Hospital; Université de Sherbrooke; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval; Canadian Institutes of Health Research; Université Laval; Canadian Diabetes Association; GlaxoSmithKline","keywords":"Brown adipose tissue; Thermogenesis; NEFA; Endocrinology; Internal medicine; Oxidative phosphorylation; Adipose tissue; Thermogenin; Biology; Carbohydrate metabolism; Metabolism; Chemistry; Biochemistry; Medicine; Insulin","score_opus":0.048651904068649686,"score_gpt":0.3657477110956015,"score_spread":0.31709580702695184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153081066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99648726,0.0018637676,0.0005786703,0.00003772605,0.000009145156,0.000021993832,0.000089451365,0.000010359736,0.0009017823],"genre_scores_gemma":[0.99912363,0.0003444841,0.00015002023,0.000032245993,0.00001764099,0.000013603176,0.000090366295,0.0000034478023,0.0002246866],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998754,0.000036167727,0.0000094201705,0.000034319422,0.00002448627,0.000020177366],"domain_scores_gemma":[0.99976534,0.000044891203,0.00008904866,0.000029893266,0.00002475239,0.000046104047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002419344,0.00026063336,0.00049241626,0.00032948234,0.00036651862,0.0004237971,0.000097909964,0.0002569344,0.0012760328],"category_scores_gemma":[0.00044405114,0.00017118998,0.00019368777,0.00024878475,0.00042617373,0.00013714995,0.00026084317,0.00030829516,0.00011935181],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008142123,0.00038864292,0.75412333,0.00033255582,0.00043527895,0.0016893982,0.00072935,0.00056134857,0.20980003,0.00020723077,0.0003388755,0.02325183],"study_design_scores_gemma":[0.000015581849,0.0006167194,0.9948879,0.00001305844,0.000050753013,0.00087865244,0.00007666035,0.00017470484,0.0029492902,0.00005360285,0.00027633266,0.0000068169825],"about_ca_topic_score_codex":0.001249832,"about_ca_topic_score_gemma":0.0012535488,"teacher_disagreement_score":0.0012760328,"about_ca_system_score_codex":0.00019111634,"about_ca_system_score_gemma":0.00015086964,"threshold_uncertainty_score":0.004268825},"labels":[],"label_agreement":null},{"id":"W2153102072","doi":"10.1172/jci85194","title":"The Canadian clinician-scientist training program must be reinstated","year":2015,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Health and Medical Research Impacts","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia Hospital; International Collaboration On Repair Discoveries; University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Canadian Hematology Society","keywords":"Mandate; Research program; Translational research; Context (archaeology); Medical education; Program director; Odds; Medical research; Political science; Medicine; Pathology","score_opus":0.7843444281488041,"score_gpt":0.6468545012931034,"score_spread":0.13748992685570072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153102072","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":"incentives","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":"incentives","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008497754,0.6242195,0.0013367805,0.3040792,0.027351914,0.00016756753,0.00035079857,0.00019802322,0.041446455],"genre_scores_gemma":[0.025273643,0.8027065,0.0057366975,0.12923774,0.0062773973,0.00023578273,0.0006794343,0.00011095838,0.029741887],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9838049,0.00279474,0.0007663779,0.00083090935,0.009188022,0.0026149675],"domain_scores_gemma":[0.9499506,0.007987764,0.0020896327,0.0016668723,0.027536659,0.010768537],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.017695248,0.0007028553,0.001468161,0.0027628988,0.003818468,0.0061520473,0.0034515676,0.0049786256,0.008423175],"category_scores_gemma":[0.032143045,0.000504,0.0009515012,0.0049756337,0.005426326,0.0043109963,0.0028774845,0.009925214,0.0036331152],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008056266,0.00005245163,0.0007562337,0.0068424703,0.00008045349,0.00012716517,0.00046179033,0.00014526652,0.0003090351,0.045631442,0.52664566,0.41886744],"study_design_scores_gemma":[0.000021432537,0.000017655027,0.0014851594,0.0028641394,0.000025267555,0.000098382385,0.00017099222,0.000022147113,0.000056121047,0.0017998823,0.9934248,0.0000140470365],"about_ca_topic_score_codex":0.5410394,"about_ca_topic_score_gemma":0.68418366,"teacher_disagreement_score":0.98230475,"about_ca_system_score_codex":0.028751852,"about_ca_system_score_gemma":0.25030813,"threshold_uncertainty_score":0.923327},"labels":[],"label_agreement":null},{"id":"W2153898363","doi":"10.1172/jci43498","title":"Pain imaging in health and disease — how far have we come?","year":2010,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":216,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Pfizer Canada; McGill University; International Association for the Study of Pain; Louise and Alan Edwards Foundation; Pfizer","keywords":"Chronic pain; Neuroscience; Neuroimaging; Medicine; Functional imaging; Disease; Placebo; Brain Structure and Function; Brain function; Psychology; Physical medicine and rehabilitation; Pathology; Alternative medicine","score_opus":0.16563776841363062,"score_gpt":0.4613808933010145,"score_spread":0.29574312488738386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153898363","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000024361636,0.9984586,0.000052351337,0.000736399,0.0003035545,0.0000019917197,0.0000035469352,0.0000028030324,0.0004163395],"genre_scores_gemma":[0.0002942947,0.9983374,0.00013120892,0.00040882628,0.0004686414,0.000004439117,0.000006351566,0.0000012832284,0.00034758617],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995265,0.00014555787,0.000068975634,0.000058829544,0.00016256468,0.000037574893],"domain_scores_gemma":[0.99826056,0.0009210963,0.0001456305,0.000059439117,0.0004685613,0.00014474185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002060837,0.0013503843,0.0030013924,0.0030468528,0.00055598817,0.002138536,0.0016289715,0.0031301752,0.0036856951],"category_scores_gemma":[0.0026287993,0.000516043,0.000615103,0.0038197576,0.002166804,0.0041536926,0.0010352427,0.003943344,0.0032814061],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009897113,0.000065911954,0.00022601696,0.0099683525,0.00007566455,0.00021595792,0.00010176527,0.00019375501,0.0005417482,0.005055631,0.05683482,0.9266215],"study_design_scores_gemma":[0.000032203425,0.00010126586,0.001384918,0.008290824,0.00009345513,0.0024382172,0.0002504541,0.000107827895,0.00020368434,0.007077201,0.97998464,0.000035273417],"about_ca_topic_score_codex":0.003087334,"about_ca_topic_score_gemma":0.004237664,"teacher_disagreement_score":0.0036856951,"about_ca_system_score_codex":0.001307337,"about_ca_system_score_gemma":0.0018358522,"threshold_uncertainty_score":0.012329817},"labels":[],"label_agreement":null},{"id":"W2154522740","doi":"10.1172/jci6539","title":"Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":300,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Hospital for Sick Children; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Apoptosis; Matrix metalloproteinase; Tenascin C; Vascular smooth muscle; Biology; Cancer research; Cell biology; Population; Immunology; Endocrinology; Medicine; Extracellular matrix; Biochemistry","score_opus":0.02223603691105288,"score_gpt":0.33866416341706396,"score_spread":0.3164281265060111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154522740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99359494,0.0020999764,0.0017523946,0.00011700889,0.000052933327,0.000041083695,0.00012305983,0.00010565309,0.0021129982],"genre_scores_gemma":[0.9933503,0.00096287753,0.0014018506,0.0000723884,0.000026011432,0.000039820552,0.0003069188,0.00001616538,0.0038236245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990726,0.00001478134,0.000008855911,0.000018596016,0.00002184711,0.000028727101],"domain_scores_gemma":[0.99992347,0.00001412261,0.000021975246,0.000008919641,0.000006383937,0.00002509932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014331068,0.00028288615,0.00017654168,0.00013158949,0.000076824705,0.00017795373,0.000106532534,0.00020409278,0.0011422585],"category_scores_gemma":[0.00015015464,0.00010742626,0.000098744546,0.000058076923,0.00022462744,0.00013988676,0.000096079224,0.0004628464,0.00024469805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041501594,0.0001295365,0.00018163498,0.000026393693,0.0000064166347,0.000053099546,0.000011299456,0.000043915024,0.9945814,0.00015843271,0.00011645233,0.004276517],"study_design_scores_gemma":[0.0002527722,0.0048186514,0.005861424,0.000010490974,0.00004546358,0.00085479126,0.00002603685,0.000981302,0.98120385,0.000121890174,0.0058179097,0.0000053044123],"about_ca_topic_score_codex":0.00027576325,"about_ca_topic_score_gemma":0.00070684403,"teacher_disagreement_score":0.0011422585,"about_ca_system_score_codex":0.0001268519,"about_ca_system_score_gemma":0.00016251917,"threshold_uncertainty_score":0.0038212538},"labels":[],"label_agreement":null},{"id":"W2154912131","doi":"10.1172/jci39254","title":"Genetic susceptibility to HIV-associated nephropathy","year":2009,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; St. Michael's Hospital; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Pathogenesis; Nephropathy; Biology; Disease; Genetics; Gene; Genetic predisposition; Genetic linkage; Immunology; Medicine; Pathology; Endocrinology; Diabetes mellitus","score_opus":0.05844807734009075,"score_gpt":0.3630601500239215,"score_spread":0.3046120726838307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154912131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64680886,0.013399901,0.0036279,0.18481223,0.0036275347,0.00023892758,0.0005002552,0.0003600189,0.14662437],"genre_scores_gemma":[0.9482558,0.0037068021,0.00081565283,0.030848674,0.0073680296,0.000049245453,0.00008451367,0.000023134562,0.008848278],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.99960977,0.00016386413,0.00002252353,0.0000580846,0.00008254809,0.00006315959],"domain_scores_gemma":[0.9992594,0.0004614332,0.000055298442,0.000056149453,0.00007887381,0.000088844936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003986632,0.0003987972,0.0005501345,0.00045400465,0.00084067427,0.00043017516,0.00026181937,0.0029976633,0.0054509267],"category_scores_gemma":[0.003211918,0.000121291,0.00020268119,0.00042660072,0.00052879157,0.0004370552,0.0002529238,0.0014468755,0.0011598477],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014441583,0.0006232763,0.31739876,0.00040617684,0.00017912665,0.39829344,0.0014751535,0.0007520044,0.01585101,0.018170908,0.10173001,0.14367604],"study_design_scores_gemma":[0.0003456368,0.00093952613,0.17949288,0.00050704763,0.00013719065,0.6754749,0.0012091877,0.0043575056,0.0029446082,0.020520557,0.11397472,0.00009628342],"about_ca_topic_score_codex":0.0007112303,"about_ca_topic_score_gemma":0.000680928,"teacher_disagreement_score":0.0054509267,"about_ca_system_score_codex":0.00033706173,"about_ca_system_score_gemma":0.0001586279,"threshold_uncertainty_score":0.018235207},"labels":[],"label_agreement":null},{"id":"W2155382351","doi":"10.1172/jci64201","title":"Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pyrogenesis (Canada)","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Retinal; Biology; Angiogenesis; Neovascularization; PEDF; Retina; Serum response factor; Vascular endothelial growth factor A; Pathology; Cell biology; Vascular endothelial growth factor; Cancer research; Transcription factor; Medicine; Neuroscience; Genetics; Gene","score_opus":0.02853728438631794,"score_gpt":0.31298348669439163,"score_spread":0.2844462023080737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155382351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99139494,0.0012869288,0.0046732826,0.00011773373,0.000021798625,0.000033010157,0.00050151563,0.00027901068,0.0016917898],"genre_scores_gemma":[0.9907698,0.0007870275,0.003759596,0.00005974424,0.000009575666,0.00004078678,0.0004083545,0.00006763295,0.004097552],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997131,0.00006065474,0.00004130665,0.000073079485,0.000068716996,0.00004305103],"domain_scores_gemma":[0.9996948,0.000046752037,0.00014921781,0.00003296152,0.000019089515,0.00005723707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024055385,0.0003936052,0.00019901285,0.00058122154,0.00014422121,0.00029882812,0.00022905244,0.0004924083,0.0015653513],"category_scores_gemma":[0.00019679866,0.00025753162,0.00021777791,0.000154059,0.00029208403,0.00019361777,0.00019045599,0.00046504172,0.0004679238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072356735,0.000031471947,0.00017304292,0.000025865145,0.0000058499027,0.00017409501,0.000017879462,0.00008694657,0.998168,0.00023295196,0.00004327476,0.00096835184],"study_design_scores_gemma":[0.00006451918,0.00050456024,0.007995124,0.000026374812,0.00004167074,0.0026507932,0.000046094967,0.002546718,0.9814585,0.00016799316,0.0044864193,0.0000112938915],"about_ca_topic_score_codex":0.00061803946,"about_ca_topic_score_gemma":0.0009571393,"teacher_disagreement_score":0.0015653513,"about_ca_system_score_codex":0.00031594405,"about_ca_system_score_gemma":0.00015737099,"threshold_uncertainty_score":0.005236566},"labels":[],"label_agreement":null},{"id":"W2155848079","doi":"10.1172/jci25463","title":"Control of homeostatic proliferation by regulatory T cells","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; School of Medicine, Vanderbilt University; School of Medicine, New York University; National Institutes of Health; National Multiple Sclerosis Society; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Multiple Sclerosis Society; York University; Vanderbilt University","keywords":"Homeostasis; Cell biology; Effector; Cell growth; Biology; T cell; Immunology; Immune system; Genetics","score_opus":0.026852671356631292,"score_gpt":0.30505264304663054,"score_spread":0.27819997168999927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155848079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9705848,0.008962451,0.012197037,0.00026325244,0.00015192556,0.0000862479,0.00011138722,0.0004755786,0.007167287],"genre_scores_gemma":[0.99284005,0.0018318672,0.003517708,0.000112632966,0.00011743728,0.00005222661,0.00007665884,0.000032061536,0.0014194066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996158,0.00012618129,0.000023213217,0.000055887616,0.00007451821,0.00010436781],"domain_scores_gemma":[0.9997546,0.00006118187,0.000055076314,0.000043905056,0.00003264751,0.000052540057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041549318,0.00029996876,0.0002660273,0.0002621473,0.00018698267,0.00046202407,0.00029838772,0.0002472093,0.0010333813],"category_scores_gemma":[0.00039312296,0.000112470756,0.00016512054,0.0000808173,0.00035436373,0.00025793165,0.00020740497,0.0008034403,0.0004228558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024811414,0.00007578269,0.0006429181,0.000050129303,0.0000037673715,0.00014253269,0.00003100751,0.00015240222,0.9798196,0.00085405516,0.0001424744,0.017837144],"study_design_scores_gemma":[0.00017661841,0.002195183,0.006700046,0.000037006124,0.000029536342,0.0017650155,0.00008236895,0.0030161494,0.96825826,0.0018321396,0.015889604,0.000018083862],"about_ca_topic_score_codex":0.00015705034,"about_ca_topic_score_gemma":0.00014735643,"teacher_disagreement_score":0.0010333813,"about_ca_system_score_codex":0.00016819713,"about_ca_system_score_gemma":0.0002714632,"threshold_uncertainty_score":0.0034570694},"labels":[],"label_agreement":null},{"id":"W2155852459","doi":"10.1172/jci33754","title":"Complex two-gene modulation of lung disease severity in children with cystic fibrosis","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":141,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"SickKids Foundation; University of Toronto; Centre Hospitalier de l’Université de Montréal; Institute for Clinical Evaluative Sciences; University of British Columbia; Hospital for Sick Children","funders":"Ontario Genomics; Ontario Genomics Institute; Genome Canada","keywords":"Cystic fibrosis; Mannan-binding lectin; Immunology; Lung; Pathogenesis; Disease; Genotype; Medicine; Respiratory disease; Pulmonary fibrosis; Gene; Biology; Pathology; Internal medicine; Genetics; Lectin","score_opus":0.07423618957161052,"score_gpt":0.39150269244761665,"score_spread":0.3172665028760061,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155852459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9995555,0.00014756531,0.000033097596,0.000027958822,0.0000011801869,0.0000031656052,0.000109959794,0.000002802242,0.00011864399],"genre_scores_gemma":[0.9995098,0.000083284525,0.00010141338,0.000015058509,0.000002289511,0.0000036038543,0.00014307663,0.0000024239246,0.00013905962],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99972576,0.00004907252,0.000013088107,0.00005753701,0.000078881196,0.00007558186],"domain_scores_gemma":[0.99954,0.000065489236,0.00020267558,0.000017295477,0.000053213953,0.000121366975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017818225,0.00033991353,0.00027843736,0.0006139819,0.00034605313,0.00034504212,0.00020525845,0.00033203434,0.0011516091],"category_scores_gemma":[0.0009266616,0.00012774103,0.00021501502,0.0006933576,0.0004128144,0.00016162822,0.0002985391,0.00040239046,0.00010028266],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027684792,0.000046926394,0.9924784,0.000011799099,0.000027565222,0.00036014372,0.00018197682,0.00006153792,0.004061383,0.00003480512,0.00010624254,0.0023523804],"study_design_scores_gemma":[0.00000483894,0.0000770125,0.9989367,0.0000022267457,0.000012025177,0.00046493797,0.00007017813,0.00008030998,0.00023700396,0.000011235677,0.0001009159,0.00000264276],"about_ca_topic_score_codex":0.08793113,"about_ca_topic_score_gemma":0.07235112,"teacher_disagreement_score":0.08793113,"about_ca_system_score_codex":0.0011693661,"about_ca_system_score_gemma":0.0011115009,"threshold_uncertainty_score":0.1748386},"labels":[],"label_agreement":null},{"id":"W2156451662","doi":"10.1172/jci10167","title":"Treatment of murine lupus with cDNA encoding IFN-γR/Fc","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute on Aging; National Institutes of Health","keywords":"Systemic lupus erythematosus; Immunology; Medicine; Autoimmune disease; Autoantibody; Pathogenesis; Genetic enhancement; Lupus erythematosus; Disease; Biology; Antibody; Pathology; Gene","score_opus":0.12716137955816825,"score_gpt":0.42572932777046774,"score_spread":0.2985679482122995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156451662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828243,0.0027168172,0.009604651,0.00038979697,0.00021950202,0.00025753834,0.0007745321,0.0005252119,0.0026877015],"genre_scores_gemma":[0.9752392,0.002144311,0.014055515,0.00016435083,0.00009017749,0.0002636422,0.0012247174,0.00008987168,0.006728152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995408,0.00009229176,0.00004580151,0.00010954651,0.000109838904,0.00010176793],"domain_scores_gemma":[0.99963593,0.00009294917,0.00010470289,0.000066498265,0.000022937546,0.000076933844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043767245,0.0007040439,0.0005374825,0.0005280932,0.00021010335,0.00037635758,0.0003498084,0.0008149597,0.0018865715],"category_scores_gemma":[0.0002638904,0.00020057896,0.00038438258,0.00028387172,0.0005664612,0.00034752087,0.00017431946,0.0017644084,0.00075578614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019942306,0.00018489988,0.00008516673,0.000053408014,0.00000802047,0.000040889754,0.000024901117,0.000100565725,0.9962453,0.0001819543,0.000074657095,0.002800763],"study_design_scores_gemma":[0.00008381735,0.0013108238,0.00040887142,0.000008184508,0.000022715392,0.0001572379,0.000008537628,0.00042574143,0.9956293,0.000037587924,0.001903164,0.000004061467],"about_ca_topic_score_codex":0.0005007999,"about_ca_topic_score_gemma":0.00063797145,"teacher_disagreement_score":0.0018865715,"about_ca_system_score_codex":0.0004821695,"about_ca_system_score_gemma":0.0003549121,"threshold_uncertainty_score":0.006311238},"labels":[],"label_agreement":null},{"id":"W2156483545","doi":"10.1172/jci80102","title":"RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre","funders":"National Institutes of Health; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; National Institute of Diabetes and Digestive and Kidney Diseases; Bundesministerium für Bildung und Forschung; E-Rare","keywords":"Kabuki syndrome; Zebrafish; Biology; MAPK/ERK pathway; Phenotype; Genetics; Mutation; Costello syndrome; Chromatin; Epigenetics; Cancer research; Cell biology; Signal transduction; Gene; KRAS","score_opus":0.06393858764674232,"score_gpt":0.3352240235914784,"score_spread":0.2712854359447361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156483545","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99463516,0.0012356583,0.0022987484,0.000073951735,0.000010333373,0.000021009873,0.00021559009,0.00014821276,0.0013612764],"genre_scores_gemma":[0.9965192,0.00084398227,0.0016340432,0.00003390091,0.0000050208787,0.000017994267,0.000103757644,0.000018539635,0.0008235945],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99989104,0.000020868381,0.0000142576255,0.000026635937,0.00003355401,0.000013503135],"domain_scores_gemma":[0.99992883,0.000014170728,0.00003137288,0.0000055232604,0.000003841352,0.00001631794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000114289986,0.0006189915,0.00031139774,0.0006441367,0.00018423847,0.00016256643,0.00022392625,0.0003694998,0.0012940431],"category_scores_gemma":[0.00019229717,0.0002871507,0.00024272852,0.00023763753,0.0004576321,0.00017924012,0.00034359173,0.00038842842,0.0004258517],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016771218,0.000029939087,0.0017952357,0.0000835516,0.000017183294,0.007399844,0.000067898145,0.00032677536,0.9851398,0.00046699392,0.00011034955,0.004394908],"study_design_scores_gemma":[0.00009776032,0.0007529176,0.086476825,0.00004969133,0.00020239185,0.11130776,0.00017391914,0.0042015263,0.7900514,0.00065951067,0.005977513,0.000048791408],"about_ca_topic_score_codex":0.0006983256,"about_ca_topic_score_gemma":0.001063097,"teacher_disagreement_score":0.0012940431,"about_ca_system_score_codex":0.00023265599,"about_ca_system_score_gemma":0.00022036333,"threshold_uncertainty_score":0.0043290257},"labels":[],"label_agreement":null},{"id":"W2156796753","doi":"10.1172/jci43134","title":"Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":313,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; University of Aberdeen; McGill University","keywords":"Arcuate nucleus; Leptin; Neurogenesis; Hypothalamus; Endocrinology; Biology; Internal medicine; Nucleus; Protein turnover; Neuroscience; Medicine; Obesity; Protein biosynthesis","score_opus":0.18389160835167473,"score_gpt":0.33587930783966324,"score_spread":0.15198769948798851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156796753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99376714,0.00091096223,0.0027225267,0.00031718763,0.000048075322,0.000036403926,0.0007473944,0.00027281579,0.0011775771],"genre_scores_gemma":[0.98450696,0.0015616324,0.0059177675,0.00031101715,0.000044915836,0.00020298715,0.0012271458,0.00024508007,0.005982479],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997255,0.000035565892,0.000030841242,0.00007896043,0.00007340939,0.00005569013],"domain_scores_gemma":[0.9996451,0.00003422602,0.00015351127,0.000033634715,0.000017744527,0.0001158176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023397269,0.00060711754,0.0004888908,0.0012293156,0.0002813377,0.0005847608,0.00047813798,0.0006064831,0.0022335749],"category_scores_gemma":[0.00022990728,0.00058834854,0.0003703001,0.00032867197,0.0008403171,0.00035028794,0.0002997649,0.0013541275,0.00055016385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007124803,0.0002543714,0.00046620105,0.000043405034,0.000021271582,0.00015374838,0.00003129196,0.00012339052,0.9950458,0.00046094984,0.000117840704,0.0025693823],"study_design_scores_gemma":[0.0009355874,0.0025544032,0.03475659,0.0000860433,0.00016683555,0.0022752266,0.00020867436,0.0042161625,0.94571227,0.0011632764,0.00787856,0.000046281923],"about_ca_topic_score_codex":0.00083556306,"about_ca_topic_score_gemma":0.0013428772,"teacher_disagreement_score":0.0022335749,"about_ca_system_score_codex":0.00043392074,"about_ca_system_score_gemma":0.00035877444,"threshold_uncertainty_score":0.0074720383},"labels":[],"label_agreement":null},{"id":"W2157430783","doi":"10.1172/jci18991","title":"TNF-α is a critical negative regulator of type 1 immune activation during intracellular bacterial infection","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":200,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Tumor necrosis factor alpha; Immune system; Immunology; Cytokine; Biology; CD8; Cytotoxic T cell; Immunity; Antigen; T cell; Necrosis; Microbiology","score_opus":0.0737972340683897,"score_gpt":0.3989588763116381,"score_spread":0.3251616422432484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157430783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8648989,0.11500798,0.010118778,0.000549938,0.0012361769,0.0001737904,0.0007833508,0.00055028975,0.006680759],"genre_scores_gemma":[0.9694819,0.02278814,0.002543244,0.00016121219,0.00031622627,0.00007133459,0.00083254476,0.000026789405,0.0037786164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978393,0.00005146161,0.000037994258,0.00003519223,0.000052756848,0.000038616145],"domain_scores_gemma":[0.99973387,0.00002341023,0.00013718836,0.000018188106,0.00004341388,0.00004391981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025936615,0.000707701,0.0003206203,0.000265397,0.00019681497,0.00038195387,0.00017405009,0.0002909323,0.0006618687],"category_scores_gemma":[0.0002632973,0.00010518897,0.0001559892,0.00015373176,0.00022584466,0.00019844816,0.00018092939,0.00043347382,0.0006693958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042056668,0.000022036056,0.001391023,0.00021308994,0.000009925241,0.00040327743,0.00004212276,0.00008556545,0.98804456,0.00016256545,0.00028101652,0.008924237],"study_design_scores_gemma":[0.00011104688,0.0013722244,0.048831996,0.00020855968,0.00011318763,0.0060791564,0.00017230964,0.0015329971,0.8916166,0.00083445036,0.04910309,0.000024374274],"about_ca_topic_score_codex":0.00013874233,"about_ca_topic_score_gemma":0.00009617181,"teacher_disagreement_score":0.000707701,"about_ca_system_score_codex":0.00033611702,"about_ca_system_score_gemma":0.00015321649,"threshold_uncertainty_score":0.0024386644},"labels":[],"label_agreement":null},{"id":"W2157907012","doi":"10.1172/jci8688","title":"Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":562,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Medical Research Council; Kidney Foundation of Canada; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Mutant; Receptor; Arginine vasopressin receptor 2; Cell biology; Cell; Chemical chaperone; Chemistry; Vasopressin receptor; HEK 293 cells; Biology; Biochemistry; Antagonist; Gene","score_opus":0.041214331622907815,"score_gpt":0.32095884426455484,"score_spread":0.279744512641647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157907012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99681807,0.0010111689,0.001019414,0.00009759234,0.000028836164,0.000019946436,0.00014911797,0.000055428594,0.0008003514],"genre_scores_gemma":[0.995628,0.000806041,0.0015244776,0.00006431813,0.000021324458,0.00002747081,0.00040369868,0.000032120155,0.0014924905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998671,0.000026506446,0.000016964366,0.000017837094,0.000036068537,0.00003551243],"domain_scores_gemma":[0.9998702,0.000032283755,0.000025621299,0.000017817938,0.000015801754,0.000038236325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001231523,0.00027037627,0.00038724698,0.00011704037,0.00012838445,0.00031621492,0.00020896895,0.00020296761,0.0007051219],"category_scores_gemma":[0.00021506155,0.00011419619,0.00014659418,0.00008891493,0.00020089802,0.000118024036,0.00014358001,0.0005125563,0.0003127547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001200814,0.000023087752,0.000056743967,0.000016769885,0.000004486821,0.000038548213,0.000010091621,0.000041692565,0.99880505,0.000052339095,0.00004397737,0.00078696164],"study_design_scores_gemma":[0.000056028977,0.0006680683,0.0016871126,0.000004487735,0.000015480418,0.00042638485,0.000029906754,0.0007491788,0.9936373,0.000036322985,0.0026850228,0.0000047543854],"about_ca_topic_score_codex":0.00038891958,"about_ca_topic_score_gemma":0.0007661482,"teacher_disagreement_score":0.0007051219,"about_ca_system_score_codex":0.00024635872,"about_ca_system_score_gemma":0.00017935413,"threshold_uncertainty_score":0.0023588538},"labels":[],"label_agreement":null},{"id":"W2157910644","doi":"10.1172/jci24340","title":"Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Deutsche Krebshilfe; Deutsche Forschungsgemeinschaft; Cancer Research Society","keywords":"Angiogenesis; Cell adhesion molecule; Arteriogenesis; Matrigel; Biology; Cell biology; Cancer research; In vivo; Selectin; Pathology; Medicine","score_opus":0.025055578190056115,"score_gpt":0.29862603639582014,"score_spread":0.27357045820576403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157910644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969699,0.0013340643,0.0005687023,0.000057279878,0.00002135931,0.000011145503,0.00008431127,0.000024634686,0.0009285608],"genre_scores_gemma":[0.9969229,0.0011339481,0.00046876847,0.000047380636,0.000014938397,0.000027935841,0.00021617541,0.00000679017,0.0011612598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998354,0.00006220616,0.0000061081605,0.000015876321,0.000022004662,0.000058421014],"domain_scores_gemma":[0.9998629,0.000041031428,0.000028622024,0.000010901743,0.000009773154,0.000046779835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016953323,0.00023609237,0.00017614989,0.00022641473,0.00011549467,0.00026292703,0.00010067914,0.00018813867,0.0007232646],"category_scores_gemma":[0.00014756735,0.00011957941,0.000107963264,0.000097694065,0.00017590972,0.00014665011,0.00007840334,0.0005029181,0.00016108205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016762881,0.000099076795,0.00016869353,0.000017982533,0.0000033471406,0.000025669526,0.000011292981,0.000052925985,0.9985531,0.00005927621,0.00005829981,0.000782661],"study_design_scores_gemma":[0.00003447611,0.0013559773,0.009387405,0.00000615451,0.000025795154,0.000121813006,0.00003140062,0.0012386669,0.98631775,0.0000578612,0.0014180898,0.000004607335],"about_ca_topic_score_codex":0.0004367235,"about_ca_topic_score_gemma":0.0007456974,"teacher_disagreement_score":0.0007232646,"about_ca_system_score_codex":0.00024812503,"about_ca_system_score_gemma":0.00012954247,"threshold_uncertainty_score":0.002419591},"labels":[],"label_agreement":null},{"id":"W2158007655","doi":"10.1172/jci37176","title":"Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes, Cardiovascular Risks, and Lipoproteins","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; National Center for Research Resources; Broad Institute","keywords":"Lipase; Nonsynonymous substitution; Biology; Cholesterol; Mutation; Internal medicine; Endocrinology; Genetics; Enzyme; Biochemistry; Medicine; Gene; Genome","score_opus":0.07333857289274275,"score_gpt":0.3547129321314933,"score_spread":0.28137435923875054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158007655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99518555,0.00207872,0.0010607523,0.00027357513,0.000025752743,0.000011445967,0.00031898028,0.00003660995,0.0010086448],"genre_scores_gemma":[0.9987865,0.00046535025,0.00030653318,0.00008308556,0.000049130136,0.0000046995365,0.00015119716,0.0000048433826,0.00014875401],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99961203,0.00009866045,0.00004979445,0.00012329065,0.00008332895,0.000032957443],"domain_scores_gemma":[0.99956375,0.00012524477,0.00017781698,0.000058380472,0.000035442725,0.000039470724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005070693,0.00051776675,0.0005312068,0.0007849232,0.00031829256,0.00040309248,0.00027987376,0.00064564275,0.0015394966],"category_scores_gemma":[0.0014091837,0.00022642034,0.0002901686,0.00083999924,0.00043894595,0.00022032592,0.00021249008,0.00051526836,0.00021617934],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003384505,0.0002493925,0.918773,0.00017309729,0.0012860186,0.007744949,0.00017404725,0.00060455326,0.037849773,0.00065685814,0.001143862,0.027959887],"study_design_scores_gemma":[0.00019856883,0.00050227874,0.963458,0.000054027976,0.0009857682,0.024645291,0.00012165156,0.0012719565,0.004942837,0.0019401368,0.0018530897,0.000026455324],"about_ca_topic_score_codex":0.0005581125,"about_ca_topic_score_gemma":0.00035197393,"teacher_disagreement_score":0.0015394966,"about_ca_system_score_codex":0.00013969773,"about_ca_system_score_gemma":0.000094904215,"threshold_uncertainty_score":0.0051501393},"labels":[],"label_agreement":null},{"id":"W2158092720","doi":"10.1172/jci28941","title":"Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":487,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Directorate for Biological Sciences; Henry Smith Charity","keywords":"FOXP3; Biology; IL-2 receptor; Population; Telomere; Cell biology; Immunology; T cell; Genetics; Immune system; Medicine; Gene","score_opus":0.05413647620024828,"score_gpt":0.31294381926563836,"score_spread":0.2588073430653901,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158092720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840029,0.003257676,0.009195675,0.00007565462,0.000021321544,0.00003843409,0.00018760125,0.00017146784,0.003049249],"genre_scores_gemma":[0.9908627,0.00086617685,0.0044710557,0.00006366777,0.00001561499,0.000049700593,0.0004103779,0.00003217437,0.003228551],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998945,0.000016642924,0.000007355499,0.000029140516,0.000025337018,0.000026951833],"domain_scores_gemma":[0.9999192,0.00002331828,0.000021310852,0.000015694004,0.000007211352,0.000013374136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002444842,0.00017428838,0.00015642203,0.00023617565,0.00012164799,0.00023294809,0.00013155586,0.00017476817,0.0014729216],"category_scores_gemma":[0.00020911785,0.00013755333,0.00012862364,0.00009470975,0.00015510226,0.00015441359,0.00014448633,0.00023577607,0.00037780375],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021967187,0.000015148211,0.0007782405,0.000028334962,0.0000039248457,0.00005955385,0.000033794502,0.00006475251,0.991614,0.0001522871,0.00005834658,0.006972059],"study_design_scores_gemma":[0.00005586622,0.00071595254,0.010222708,0.000014331292,0.00003184519,0.0008730309,0.0000439638,0.0007877488,0.9792747,0.00027467994,0.007695994,0.000009067546],"about_ca_topic_score_codex":0.00026102204,"about_ca_topic_score_gemma":0.00039415288,"teacher_disagreement_score":0.0014729216,"about_ca_system_score_codex":0.00011775448,"about_ca_system_score_gemma":0.00013130221,"threshold_uncertainty_score":0.004927397},"labels":[],"label_agreement":null},{"id":"W2159267239","doi":"10.1172/jci66603","title":"Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett’s metaplasia","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; RIKEN; National Institute of Child Health and Human Development; American Cancer Society; U.S. Department of Veterans Affairs; Ministry of Education, Culture, Sports, Science and Technology; Victorian Cancer Agency","keywords":"FOXA2; Metaplasia; Barrett's esophagus; Esophagus; Cancer research; Biology; Mucin 2; Intestinal metaplasia; Epithelium; Sonic hedgehog; Pathology; Dysplasia; Adenocarcinoma; Signal transduction; Transcription factor; Medicine; Cell biology; Gene expression; Anatomy; Cancer","score_opus":0.045093113120697935,"score_gpt":0.3292479470615772,"score_spread":0.28415483394087926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159267239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98479503,0.009663263,0.001161904,0.00019408161,0.000036889258,0.000052540974,0.0003118005,0.000042912066,0.0037417153],"genre_scores_gemma":[0.99067277,0.0026695572,0.0013534543,0.000124321,0.00001621955,0.000048211034,0.0004685628,0.000009700257,0.0046372064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992347,0.000013723329,0.000004368756,0.000015391635,0.000025144072,0.00001788931],"domain_scores_gemma":[0.9999579,0.0000056215904,0.000009230716,0.0000028386428,0.000007207685,0.000017320572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018871033,0.0002070971,0.00016632337,0.00030442775,0.00021988105,0.0001913481,0.000094108655,0.0002479803,0.0011444831],"category_scores_gemma":[0.00010006792,0.00011602883,0.00016554462,0.00020129453,0.00020505811,0.00012049765,0.00011886604,0.0002505319,0.0002652548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007538609,0.000054254564,0.0057207923,0.00010406643,0.000015299116,0.00044075155,0.000050891387,0.000031021824,0.98605597,0.00022780849,0.00017945965,0.006365778],"study_design_scores_gemma":[0.00010670618,0.0009964823,0.25087517,0.0000324019,0.00009711976,0.002811208,0.00015817599,0.0006474487,0.7303777,0.00023771494,0.013650406,0.000009517741],"about_ca_topic_score_codex":0.0007856318,"about_ca_topic_score_gemma":0.001187333,"teacher_disagreement_score":0.0011444831,"about_ca_system_score_codex":0.00028143267,"about_ca_system_score_gemma":0.00021405259,"threshold_uncertainty_score":0.0038286448},"labels":[],"label_agreement":null},{"id":"W2159289955","doi":"10.1172/jci9110","title":"Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Deutsche Forschungsgemeinschaft","keywords":"Exocytosis; Internal medicine; Endocrinology; Secretion; Stimulation; Basal (medicine); Cholecystokinin; Acinar cell; Protein kinase C; Cell biology; Acinus; Chemistry; Biology; Pancreas; Signal transduction; Receptor; Medicine","score_opus":0.046079047990095844,"score_gpt":0.3160476485824605,"score_spread":0.26996860059236466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159289955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966163,0.0011269036,0.0015426114,0.00007293763,0.000021276262,0.000013415789,0.000089520305,0.000038073387,0.000478934],"genre_scores_gemma":[0.99698037,0.00052285125,0.0017159728,0.000055647484,0.000008102907,0.000022556034,0.000122043806,0.000009827087,0.0005625999],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998536,0.000013521057,0.000017986165,0.00003480284,0.000034420707,0.000045567987],"domain_scores_gemma":[0.9999064,0.00001689058,0.000020097983,0.000015222739,0.000006668906,0.000034589164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012220035,0.00024080055,0.00040104362,0.0001377078,0.00018517507,0.00046073546,0.00015075934,0.00025206845,0.0009653571],"category_scores_gemma":[0.00017658494,0.00013687924,0.00017761384,0.0001419397,0.00034419628,0.00030119327,0.00028608716,0.00063375843,0.00020839988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095929674,0.0000074440095,0.00007448374,0.0000133485455,0.0000010875741,0.000023886074,0.0000036555205,0.0000105012605,0.9993011,0.000028770533,0.0000057940565,0.00043400013],"study_design_scores_gemma":[0.00001027375,0.00012900612,0.0022650491,0.0000019857096,0.000005243036,0.00015798082,0.000015418109,0.00023774744,0.9966408,0.000029187308,0.00050507,0.000002278704],"about_ca_topic_score_codex":0.00033767958,"about_ca_topic_score_gemma":0.000534224,"teacher_disagreement_score":0.0009653571,"about_ca_system_score_codex":0.00058018847,"about_ca_system_score_gemma":0.0002398899,"threshold_uncertainty_score":0.004209578},"labels":[],"label_agreement":null},{"id":"W2159329774","doi":"10.1172/jci12412","title":"Complete heart block and sudden death in mice overexpressing calreticulin","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Calgary; University of Alberta; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; AstraZeneca","keywords":"Calreticulin; Embryonic heart; Endoplasmic reticulum; Internal medicine; Heart block; Sudden death; Sinus bradycardia; Bradycardia; Downregulation and upregulation; Sinoatrial node; Biology; Heart development; Sudden cardiac death; Heart failure; Endocrinology; Cell biology; Medicine; Heart rate; Embryonic stem cell; Electrocardiography; Gene; Genetics; Blood pressure","score_opus":0.056989475814005916,"score_gpt":0.35513869903345996,"score_spread":0.29814922321945403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159329774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99435896,0.0008645724,0.0025261196,0.00012234262,0.0000399766,0.000050291408,0.0004784226,0.00018822416,0.0013711195],"genre_scores_gemma":[0.9910453,0.0011476179,0.0019044268,0.00015951508,0.000028588898,0.0001243694,0.001331396,0.00007003002,0.0041886605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985516,0.000028948998,0.000011893444,0.00004128329,0.000030721065,0.00003187246],"domain_scores_gemma":[0.99969876,0.00003934751,0.00011391162,0.000023879724,0.0000177105,0.000106326566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018402429,0.00078859273,0.000416076,0.00045696838,0.00023087932,0.00022954369,0.00017219203,0.0005566162,0.001971707],"category_scores_gemma":[0.00022054494,0.0003039629,0.00031787952,0.000122004385,0.00042342982,0.00028105377,0.00037350922,0.0007792818,0.00046477604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001455385,0.000182668,0.0025710629,0.00007339044,0.000040242496,0.002448801,0.00009846384,0.00019402783,0.9864507,0.0003532162,0.00024719528,0.005884955],"study_design_scores_gemma":[0.0015125443,0.017445453,0.24463432,0.00015799116,0.00039988905,0.04577064,0.00029194186,0.005266164,0.67332345,0.0014487047,0.009648436,0.000100471276],"about_ca_topic_score_codex":0.000307871,"about_ca_topic_score_gemma":0.00048488303,"teacher_disagreement_score":0.001971707,"about_ca_system_score_codex":0.00017009495,"about_ca_system_score_gemma":0.0001810483,"threshold_uncertainty_score":0.0065960884},"labels":[],"label_agreement":null},{"id":"W2159346623","doi":"10.1172/jci31021","title":"Obesity-associated improvements in metabolic profile through expansion of adipose tissue","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":1299,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; American Diabetes Association; American Heart Association; Albert Einstein College of Medicine, Yeshiva University","keywords":"Adipose tissue; Internal medicine; Endocrinology; Insulin resistance; Adiponectin; Leptin; Metabolic syndrome; FGF21; Triglyceride; Insulin; Adipose tissue macrophages; Inflammation; White adipose tissue; Obesity; Biology; Medicine; Cholesterol","score_opus":0.05580841231074944,"score_gpt":0.38042664156410866,"score_spread":0.3246182292533592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159346623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99178785,0.0026211813,0.0031648104,0.00024560586,0.000035432415,0.000023834045,0.00013187155,0.00009235524,0.0018969884],"genre_scores_gemma":[0.9926085,0.0021760932,0.0026756602,0.0001265791,0.00003092095,0.000020333879,0.00022142055,0.000012959461,0.0021276765],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99995804,0.000010361899,0.0000032531425,0.000007803057,0.000010408627,0.000010160318],"domain_scores_gemma":[0.99995387,0.000005005383,0.000015197192,0.0000061398982,0.000003637981,0.000016094613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014490659,0.00025422184,0.00019314833,0.00017092412,0.00007632669,0.0002576839,0.000070624585,0.00011559384,0.0013065136],"category_scores_gemma":[0.00009160356,0.00007934547,0.00008647969,0.00014972257,0.00030023255,0.00013551665,0.00017430683,0.00045753721,0.00019825753],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010208761,0.00016074702,0.005503069,0.000121114754,0.000018414126,0.00054445793,0.000024045701,0.000117958305,0.97056806,0.00060365745,0.00022516506,0.021092452],"study_design_scores_gemma":[0.00042079916,0.008404617,0.18752666,0.00008126543,0.00019962613,0.023640925,0.00022304739,0.002537002,0.7552822,0.0026278587,0.019024149,0.000031771204],"about_ca_topic_score_codex":0.00007967225,"about_ca_topic_score_gemma":0.00018089075,"teacher_disagreement_score":0.0013065136,"about_ca_system_score_codex":0.00009670012,"about_ca_system_score_gemma":0.00013062748,"threshold_uncertainty_score":0.0043706894},"labels":[],"label_agreement":null},{"id":"W2160878167","doi":"10.1172/jci27238","title":"Neutrophils and their Fc  receptors are essential in a mouse model of transfusion-related acute lung injury","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Blood transfusion and management","field":"Medicine","cited_by":302,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; GlaxoSmithKline","keywords":"Transfusion-related acute lung injury; Receptor; Medicine; Lung; Immunology; Internal medicine; Pulmonary edema","score_opus":0.03054032103551589,"score_gpt":0.3222820283976401,"score_spread":0.2917417073621242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160878167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9816648,0.004372436,0.0099113695,0.0009253376,0.00014517196,0.00023487565,0.0007239141,0.0003317554,0.0016902527],"genre_scores_gemma":[0.98407745,0.002033838,0.007720856,0.00029304295,0.000051892745,0.00040424115,0.0008102997,0.000050894192,0.0045575253],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936265,0.0002006319,0.000092144546,0.000099456476,0.00013867457,0.00010656852],"domain_scores_gemma":[0.9995065,0.000060066275,0.00019166587,0.00007731398,0.000033559372,0.00013080702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006197087,0.0010625437,0.000558191,0.00064718665,0.0003047385,0.000606,0.0006949257,0.0012305686,0.0015166656],"category_scores_gemma":[0.00040047552,0.0005410018,0.00042437296,0.00021818423,0.0006241094,0.0006762423,0.00032038317,0.002283381,0.00051199115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012628182,0.00041479507,0.00046518553,0.0000949073,0.000012821249,0.00036977316,0.000053039465,0.00018286219,0.99397343,0.0006276715,0.00018310685,0.00235957],"study_design_scores_gemma":[0.00056382216,0.0046742796,0.0079835635,0.000094977644,0.00010589057,0.0034538019,0.00011469654,0.004261197,0.9705546,0.0005265562,0.0076406444,0.000026080399],"about_ca_topic_score_codex":0.00050314516,"about_ca_topic_score_gemma":0.00068433105,"teacher_disagreement_score":0.0015166656,"about_ca_system_score_codex":0.00057338434,"about_ca_system_score_gemma":0.00040021868,"threshold_uncertainty_score":0.005073786},"labels":[],"label_agreement":null},{"id":"W2160976069","doi":"10.1172/jci22753","title":"Can antibodies with specificity for soluble antigens mimic the therapeutic effects of intravenous IgG in the treatment of autoimmune disease?","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canadian Blood Services; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Bayer Canada; Canadian Blood Services","keywords":"Immunology; Antibody; Antigen; Thrombocytopenic purpura; Immune system; Autoimmune disease; Medicine; Autoimmunity; Immunoglobulin G","score_opus":0.05867444117651278,"score_gpt":0.35308205368475354,"score_spread":0.29440761250824077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160976069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71776336,0.20282245,0.038840584,0.016477529,0.0041740797,0.00037872556,0.00021881743,0.00071230525,0.018612178],"genre_scores_gemma":[0.92524165,0.05431057,0.013098784,0.0034475927,0.00080025796,0.00010576116,0.00016147981,0.000040873372,0.002793019],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979335,0.000079555,0.000012482816,0.000022470507,0.000038143724,0.000054041888],"domain_scores_gemma":[0.99986184,0.000031022573,0.000044317974,0.00001715852,0.000018261491,0.000027358585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066049467,0.00027674198,0.00040367467,0.00023985053,0.00007133951,0.000432701,0.0003290611,0.0008712079,0.00077547744],"category_scores_gemma":[0.00048643505,0.00011806445,0.00025120596,0.0001498927,0.00043848634,0.00057518046,0.00015167768,0.00091805536,0.0004421544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002103989,0.0017113319,0.0022325492,0.0011639738,0.00020944104,0.0006696332,0.000131051,0.0014252386,0.7061034,0.0064198705,0.0038152162,0.27401426],"study_design_scores_gemma":[0.002941765,0.053235848,0.018773578,0.0005260203,0.0010894001,0.008482546,0.00028862816,0.0047150995,0.64795756,0.0068463115,0.25502017,0.00012304998],"about_ca_topic_score_codex":0.00028622767,"about_ca_topic_score_gemma":0.00046686034,"teacher_disagreement_score":0.0008712079,"about_ca_system_score_codex":0.0002080221,"about_ca_system_score_gemma":0.00020173973,"threshold_uncertainty_score":0.0034930706},"labels":[],"label_agreement":null},{"id":"W2161071827","doi":"10.1172/jci42758","title":"Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Norwegian Biodiversity Information Centre; Nierstichting","keywords":"Biology; Cytotoxic T cell; CD8; Granzyme B; Perforin; Human cytomegalovirus; Chemokine; Granzyme; Immune system; T cell; Granzyme A; Chemokine receptor; Immunology; Virology; Virus; Cell biology","score_opus":0.09101594158875564,"score_gpt":0.4107274644319161,"score_spread":0.31971152284316046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161071827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98283976,0.00471718,0.006165731,0.00007045211,0.000036376237,0.00012005561,0.0030206798,0.00010301956,0.0029267508],"genre_scores_gemma":[0.97887176,0.0034563886,0.0086205425,0.00013091555,0.00003216348,0.00018195318,0.0053540613,0.000032795593,0.0033194209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991286,0.000009418279,0.0000053578838,0.000026373133,0.00002428532,0.000021670625],"domain_scores_gemma":[0.99995947,0.000008539,0.0000073623146,0.0000039219262,0.000012954825,0.000007699909],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007965706,0.00012748488,0.00014844503,0.00043745013,0.00011313541,0.00029657345,0.00006655309,0.00021175186,0.00077279593],"category_scores_gemma":[0.00011450095,0.00007563734,0.000098880984,0.00037186497,0.00008775218,0.00008967823,0.00010890044,0.00029113152,0.0004215482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000871895,0.0000079055235,0.00066517055,0.000031946,0.000002529433,0.000022136051,0.000019252322,0.00003701859,0.9966324,0.000023282162,0.00003845468,0.0024327491],"study_design_scores_gemma":[0.00001809519,0.00038227488,0.07858076,0.000022061355,0.00004085132,0.0004368242,0.000110958594,0.0019465904,0.90848804,0.00012822475,0.009835892,0.000009423289],"about_ca_topic_score_codex":0.00026427666,"about_ca_topic_score_gemma":0.00046545969,"teacher_disagreement_score":0.00077279593,"about_ca_system_score_codex":0.00012396277,"about_ca_system_score_gemma":0.000098985984,"threshold_uncertainty_score":0.0025852919},"labels":[],"label_agreement":null},{"id":"W2162161302","doi":"10.1172/jci57313","title":"The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin–associated hemolytic uremic syndrome in humans and mice","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University Health Network; University of Toronto; Centre for Global Health Research; Toronto General Hospital; St. Michael's Hospital","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto","keywords":"Pathogenesis; Shiga toxin; Biology; Gene expression; CXCR4; Immunology; Hemolytic anemia; Chemokine; Gene; Virulence; Inflammation; Genetics","score_opus":0.042714014762867875,"score_gpt":0.3073169262770466,"score_spread":0.2646029115141787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162161302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9655985,0.019231422,0.008669303,0.0011915914,0.00017177901,0.00012442819,0.0005494507,0.00022892108,0.0042345924],"genre_scores_gemma":[0.9889542,0.005088838,0.0027723168,0.00040557995,0.00006486807,0.00007667361,0.00039645666,0.000011685013,0.0022294286],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998518,0.00005777296,0.000007600462,0.000021826472,0.000027871152,0.000033004013],"domain_scores_gemma":[0.9999496,0.0000043727127,0.000015829342,0.0000051319344,0.0000065998734,0.000018463823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023527014,0.00035957788,0.00020862254,0.00025043232,0.00015464255,0.00021353136,0.000112130445,0.00036098284,0.0023619337],"category_scores_gemma":[0.000089445835,0.00015442815,0.00030555073,0.00007671804,0.00024676166,0.00012301569,0.00021240865,0.0007216732,0.0002809185],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076791685,0.00018965467,0.0049324096,0.00024435052,0.000052880103,0.0005906703,0.000054817854,0.0003259771,0.97540635,0.001215779,0.0011093753,0.015109851],"study_design_scores_gemma":[0.0012765196,0.008212717,0.3118398,0.0004016701,0.0006322645,0.015227885,0.00048026763,0.025421014,0.56209177,0.0034254442,0.07089693,0.00009374401],"about_ca_topic_score_codex":0.00043300487,"about_ca_topic_score_gemma":0.00028556856,"teacher_disagreement_score":0.0023619337,"about_ca_system_score_codex":0.00022686073,"about_ca_system_score_gemma":0.00027706748,"threshold_uncertainty_score":0.00790143},"labels":[],"label_agreement":null},{"id":"W2162201817","doi":"10.1172/jci21060","title":"New insights into atopic dermatitis","year":2004,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":1407,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Christie (Canada)","funders":"","keywords":"Atopic dermatitis; Medicine; Immunology; Asthma; Dermatology; Disease; Phenotype; Atopy; Biology; Pathology; Gene","score_opus":0.12148370579099642,"score_gpt":0.4382144312739039,"score_spread":0.3167307254829075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162201817","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000063349595,0.99818546,0.00008063586,0.00033724177,0.00040511388,0.00000223845,0.000005736303,0.0000055084056,0.0009147009],"genre_scores_gemma":[0.00042720765,0.9982134,0.00015182386,0.0002872611,0.00039942446,0.0000029532757,0.000010788889,9.803633e-7,0.0005061891],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996524,0.00006739877,0.000045841494,0.00005429658,0.00014706455,0.00003304403],"domain_scores_gemma":[0.9996277,0.0001561553,0.000037328497,0.000018757457,0.000111256246,0.00004877318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007448913,0.0011903532,0.001977169,0.0027703648,0.00040985394,0.0014689994,0.0010243162,0.0016275622,0.0048367786],"category_scores_gemma":[0.0008698829,0.00031174347,0.00060030835,0.002575836,0.00076750194,0.0023988727,0.00090260536,0.0026987174,0.0037081952],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007657664,0.000087651155,0.00021885191,0.012671415,0.00008379971,0.0008189375,0.00013888355,0.00021291422,0.0021834106,0.0058460445,0.046228778,0.9314327],"study_design_scores_gemma":[0.000022014328,0.00006350217,0.00066973927,0.002982471,0.000051063642,0.0033826006,0.00009297433,0.00004777878,0.00022854382,0.0034571378,0.98898786,0.000014263693],"about_ca_topic_score_codex":0.00080164237,"about_ca_topic_score_gemma":0.0014697068,"teacher_disagreement_score":0.0048367786,"about_ca_system_score_codex":0.0007581139,"about_ca_system_score_gemma":0.0009645921,"threshold_uncertainty_score":0.016180575},"labels":[],"label_agreement":null},{"id":"W2162444478","doi":"10.1172/jci22760","title":"A novel COL1A1 mutation in infantile cortical hyperostosis (Caffey disease) expands the spectrum of collagen-related disorders","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Osteomyelitis and Bone Disorders Research","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Arthritis Network; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Public Health Service; National Institutes of Health; Lastentautien Tutkimussäätiö; Novo Nordisk; Canadian Institutes of Health Research; European Society for Paediatric Endocrinology; Massachusetts General Hospital","keywords":"Missense mutation; Hyperostosis; Exon; Locus (genetics); Pathology; Medicine; Biology; Genetics; Anatomy; Mutation; Gene","score_opus":0.050920442569240464,"score_gpt":0.3787556705562603,"score_spread":0.32783522798701986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162444478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99749184,0.00057328976,0.000518812,0.0001265301,0.000027328351,0.00002172741,0.00012842855,0.000036331014,0.0010756116],"genre_scores_gemma":[0.9986273,0.00017074194,0.00055571663,0.00005767172,0.000040450046,0.0000073035235,0.00007932312,0.000006344207,0.00045521258],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.99983764,0.000020274763,0.000014262629,0.000053866246,0.000037803908,0.000036146503],"domain_scores_gemma":[0.99972063,0.00009481994,0.00006766356,0.000010240505,0.000021205647,0.00008533245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015903635,0.0007760367,0.00028319214,0.0008192772,0.0004086245,0.00021352341,0.00027536522,0.0007712741,0.0015847553],"category_scores_gemma":[0.00078701845,0.0001488074,0.0002229595,0.000360417,0.00042311166,0.00013000355,0.0002716364,0.00027053436,0.00022317216],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084540725,0.00022797933,0.08972575,0.00023282414,0.000090264744,0.6392769,0.0009408445,0.00047775827,0.23582904,0.00060680666,0.0017408588,0.030005636],"study_design_scores_gemma":[0.00013015975,0.0004891443,0.35383487,0.000084268744,0.00011210771,0.6157167,0.00016515046,0.0012083765,0.02187643,0.00023511169,0.0061146133,0.000033191922],"about_ca_topic_score_codex":0.0024908492,"about_ca_topic_score_gemma":0.0028912425,"teacher_disagreement_score":0.0024908492,"about_ca_system_score_codex":0.00027130952,"about_ca_system_score_gemma":0.00016405995,"threshold_uncertainty_score":0.0053015947},"labels":[],"label_agreement":null},{"id":"W2162894871","doi":"10.1172/jci58128","title":"Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":291,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"NHLBI Division of Intramural Research; National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; American Asthma Foundation; Welch Foundation","keywords":"Paracrine signalling; Metastasis; Autocrine signalling; Cancer research; Biology; Cancer; Cancer cell; Endogeny; Carcinogenesis; Receptor; Endocrinology; Biochemistry","score_opus":0.08813769381842418,"score_gpt":0.3625654560270484,"score_spread":0.27442776220862425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162894871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869746,0.0018019029,0.006225666,0.0007034094,0.00013944598,0.00015779462,0.000986494,0.00049711304,0.0025136387],"genre_scores_gemma":[0.9816491,0.00211692,0.0051216446,0.00038281135,0.00007649757,0.00029586605,0.0011655029,0.000113173664,0.00907843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995648,0.00008968913,0.00003818286,0.00010365971,0.00008460056,0.00011905745],"domain_scores_gemma":[0.99953794,0.000055159828,0.00013875168,0.000059927068,0.00002701707,0.0001812157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047621183,0.00079909846,0.00055273256,0.0012992258,0.00032076705,0.00045200813,0.0003849106,0.0006628181,0.002150461],"category_scores_gemma":[0.00021798356,0.00044535656,0.00076700246,0.00040866327,0.00056845456,0.00051786547,0.00043231528,0.002197414,0.00051335356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013385419,0.000850698,0.000546625,0.000058641563,0.000024182495,0.00013591237,0.000049703558,0.00019413982,0.99273795,0.0003861097,0.00025791881,0.0034196156],"study_design_scores_gemma":[0.0005148562,0.009894049,0.009313116,0.000043792606,0.00010901534,0.00053594995,0.0001133471,0.0048455927,0.969085,0.0005112095,0.0050027133,0.000031276755],"about_ca_topic_score_codex":0.0007656647,"about_ca_topic_score_gemma":0.0018352949,"teacher_disagreement_score":0.002150461,"about_ca_system_score_codex":0.0005881125,"about_ca_system_score_gemma":0.000424137,"threshold_uncertainty_score":0.0071939826},"labels":[],"label_agreement":null},{"id":"W2162919259","doi":"10.1172/jci14080","title":"The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":878,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Institutes of Health","keywords":"Diabetic cardiomyopathy; Internal medicine; Endocrinology; Peroxisome proliferator-activated receptor; Beta oxidation; Heart failure; Cardiomyopathy; Biology; Phenotype; Fatty acid metabolism; Glucose uptake; Fatty acid; Metabolism; Receptor; Insulin; Medicine; Gene; Biochemistry","score_opus":0.07587762791124153,"score_gpt":0.32346502885247663,"score_spread":0.2475874009412351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162919259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99333715,0.00077767635,0.0023730483,0.00014435142,0.000084805455,0.000042580115,0.00036868933,0.000096250806,0.0027754407],"genre_scores_gemma":[0.9929934,0.00088866043,0.0023077712,0.00012319052,0.000020952924,0.00007051571,0.00065063086,0.00003584365,0.0029090506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982363,0.000035801313,0.000022688504,0.00003280495,0.000043922453,0.000041129282],"domain_scores_gemma":[0.99983716,0.000018641143,0.000057034278,0.000028026885,0.0000083472005,0.000050700975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001817521,0.00034693297,0.00023338138,0.0003176081,0.00021365988,0.0003331927,0.00012301006,0.000259115,0.0014366707],"category_scores_gemma":[0.00015481134,0.00017579652,0.00019357698,0.00024952355,0.00030931615,0.00014144681,0.0002591501,0.00067081064,0.00039339572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004396034,0.00006592385,0.0009904267,0.000024539004,0.000008487702,0.00040871318,0.000013832074,0.000085121384,0.9963295,0.00028414035,0.000053716674,0.0012961179],"study_design_scores_gemma":[0.00031914207,0.0033814034,0.056982882,0.000044573397,0.0001011999,0.010494159,0.00022576562,0.0019373652,0.9121323,0.0008089043,0.013542684,0.00002959495],"about_ca_topic_score_codex":0.00020379233,"about_ca_topic_score_gemma":0.00030111,"teacher_disagreement_score":0.0014366707,"about_ca_system_score_codex":0.00018062636,"about_ca_system_score_gemma":0.00015357294,"threshold_uncertainty_score":0.004806161},"labels":[],"label_agreement":null},{"id":"W2163953596","doi":"10.1172/jci43273","title":"Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":195,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"NIHR Cambridge Biomedical Research Centre; Vlaamse regering; Science Foundation Ireland; National Institute for Health and Care Research; Wellcome Trust","keywords":"Inflammation; Hypoxia (environmental); Downregulation and upregulation; Apoptosis; In vivo; Biology; Mediator; Immunology; Hypoxia-inducible factors; Programmed cell death; Neutrophil extracellular traps; Cell biology; Chemistry; Biochemistry; Oxygen","score_opus":0.049708358268752466,"score_gpt":0.3249942535052365,"score_spread":0.275285895236484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163953596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9420291,0.017334647,0.02919918,0.0018465265,0.00019538475,0.00017571778,0.0034193958,0.0006222653,0.005177778],"genre_scores_gemma":[0.98888016,0.002816008,0.0053504636,0.00026325733,0.000038113376,0.00009347575,0.00072140555,0.00003700556,0.0018001786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998348,0.000036295278,0.000013759157,0.00005346301,0.000031361553,0.000030434256],"domain_scores_gemma":[0.999856,0.000014308804,0.000064793,0.000015786527,0.000008751987,0.000040404066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002624109,0.000274479,0.00027270993,0.00030280132,0.00024769627,0.000326414,0.00018778704,0.00044216536,0.0017033207],"category_scores_gemma":[0.00023913149,0.00018166425,0.00032770642,0.00017294368,0.0004277368,0.00013900585,0.0003008122,0.00049816846,0.00027470913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014785834,0.00007913419,0.003870447,0.00022454423,0.000068923204,0.0009289666,0.00005553568,0.00025100965,0.9672867,0.0015605289,0.0013181838,0.022877447],"study_design_scores_gemma":[0.0008589788,0.0029504332,0.22230287,0.00020734742,0.0004332385,0.029087516,0.00024658267,0.005176004,0.623054,0.0041546533,0.11143611,0.000092279806],"about_ca_topic_score_codex":0.00062163005,"about_ca_topic_score_gemma":0.0004688882,"teacher_disagreement_score":0.0017033207,"about_ca_system_score_codex":0.00030679745,"about_ca_system_score_gemma":0.00038555643,"threshold_uncertainty_score":0.005698204},"labels":[],"label_agreement":null},{"id":"W2164871064","doi":"10.1172/jci34862","title":"Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Lupus nephritis; Angiotensin II; Angiotensin II receptor type 1; Glomerulonephritis; Medicine; Internal medicine; Inflammation; Endocrinology; Kidney; Losartan; Renin–angiotensin system; Angiotensin receptor; Immunology; Receptor; Disease; Blood pressure","score_opus":0.03153582202775223,"score_gpt":0.342610950713206,"score_spread":0.3110751286854538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164871064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99061954,0.0044402913,0.0019240917,0.00014661488,0.00007773399,0.000048834052,0.00022863639,0.00034764045,0.0021667893],"genre_scores_gemma":[0.99219733,0.0018765663,0.0030466593,0.00012534022,0.00005443225,0.00005618229,0.00029029438,0.0000346234,0.0023185024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993926,0.00014971998,0.00007011835,0.00009224851,0.00018055167,0.00011472272],"domain_scores_gemma":[0.99954176,0.000043471366,0.00014628457,0.000046749916,0.00003046465,0.00019120087],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037776123,0.0008254286,0.0005996804,0.0011599273,0.00019852085,0.00041026616,0.00023114342,0.00059870107,0.0013847149],"category_scores_gemma":[0.00021313169,0.0003485715,0.00041382943,0.00029259213,0.0003314954,0.00034456383,0.00038082965,0.0011883763,0.0004022963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041817845,0.0001845006,0.00036897327,0.000061143786,0.00001205868,0.00012333578,0.00002967806,0.000103176164,0.9966865,0.00008463874,0.000042510965,0.0018852995],"study_design_scores_gemma":[0.00028154775,0.0062636533,0.030873252,0.000048904396,0.00017318332,0.0019292372,0.00009689148,0.0038871178,0.9513533,0.00047272668,0.0045824796,0.00003771467],"about_ca_topic_score_codex":0.00041198163,"about_ca_topic_score_gemma":0.00087720866,"teacher_disagreement_score":0.0013847149,"about_ca_system_score_codex":0.00031798016,"about_ca_system_score_gemma":0.00026316178,"threshold_uncertainty_score":0.004632294},"labels":[],"label_agreement":null},{"id":"W2165322090","doi":"10.1172/jci43004","title":"The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Washington; U.S. Department of Veterans Affairs","keywords":"Bronchoalveolar lavage; Fas ligand; In vivo; In vitro; Myeloperoxidase; Immunology; Proteases; Chemistry; Lung; Inflammation; Biology; Medicine; Apoptosis; Biochemistry; Programmed cell death; Internal medicine; Enzyme","score_opus":0.31747129465230095,"score_gpt":0.42651289571228734,"score_spread":0.10904160105998639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165322090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9414785,0.029472249,0.019615889,0.00096967444,0.00020166556,0.00011331643,0.0020485374,0.00030699314,0.0057931263],"genre_scores_gemma":[0.9718032,0.006529397,0.0106811775,0.00023863174,0.000041375068,0.00014326886,0.0030042832,0.000036593203,0.007522102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996567,0.000092752845,0.00004103102,0.00008225577,0.000081376114,0.000045965146],"domain_scores_gemma":[0.99988544,0.000021016878,0.000034060802,0.000016212141,0.000015294494,0.000028024228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041937697,0.00046966923,0.00017492588,0.0007291697,0.0001706733,0.00044172132,0.00019836948,0.00040360697,0.0029363798],"category_scores_gemma":[0.00019389232,0.00015664562,0.00029671146,0.0003035155,0.00034959253,0.00036005126,0.00018672789,0.0007071074,0.0007959054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040593612,0.000040349198,0.00033880444,0.00007303,0.000009656077,0.00005744422,0.000032195545,0.000037812315,0.99527055,0.0002795991,0.000077560464,0.0033771133],"study_design_scores_gemma":[0.000060848986,0.00070969894,0.005138334,0.000030852916,0.000030841795,0.00089451857,0.00004754174,0.00077626447,0.98052245,0.00026272688,0.011517529,0.00000826005],"about_ca_topic_score_codex":0.0004337888,"about_ca_topic_score_gemma":0.0005275058,"teacher_disagreement_score":0.0029363798,"about_ca_system_score_codex":0.0003880365,"about_ca_system_score_gemma":0.00024689132,"threshold_uncertainty_score":0.009823203},"labels":[],"label_agreement":null},{"id":"W2165895874","doi":"10.1172/jci33622","title":"Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":369,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Eli Lilly and Company; National Institute on Aging; National Institutes of Health; American Health Assistance Foundation","keywords":"ABCA1; Apolipoprotein E; Genetically modified mouse; Transgene; Endocrinology; Dentate gyrus; Alzheimer's disease; Internal medicine; Amyloid (mycology); Biology; Chemistry; Cell biology; Hippocampal formation; Medicine; Transporter; Biochemistry; Disease","score_opus":0.11995265806560154,"score_gpt":0.36319679272685146,"score_spread":0.24324413466124992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165895874","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98533267,0.004449683,0.00453646,0.0004996023,0.00018125075,0.00016739377,0.0010707552,0.0007494045,0.0030127764],"genre_scores_gemma":[0.9785615,0.005798459,0.005199807,0.00025210425,0.00007332553,0.00043174112,0.0019084023,0.00014679861,0.007627871],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99959856,0.000065588654,0.000059497448,0.000079282625,0.000108016815,0.00008916833],"domain_scores_gemma":[0.9996557,0.000042199423,0.000104205,0.000038889793,0.000046385554,0.00011272383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003494919,0.0009459286,0.0011022394,0.001133623,0.00038459277,0.00067892607,0.00047687895,0.001123794,0.0018739338],"category_scores_gemma":[0.00029709982,0.00041914076,0.00049231114,0.00061624637,0.00041391051,0.00050762325,0.00029848274,0.0015148196,0.0008481495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006306819,0.0005648301,0.00031579973,0.00010885121,0.000031185562,0.00019248125,0.000037547114,0.00011840909,0.99458045,0.00020933092,0.00026840458,0.0029420014],"study_design_scores_gemma":[0.00054858736,0.0047310763,0.010455052,0.00009065544,0.00024951072,0.0014865047,0.00014081622,0.0032776538,0.96787775,0.0005292671,0.010573386,0.000039648454],"about_ca_topic_score_codex":0.0008882178,"about_ca_topic_score_gemma":0.0010378744,"teacher_disagreement_score":0.0018739338,"about_ca_system_score_codex":0.00048797388,"about_ca_system_score_gemma":0.00033963012,"threshold_uncertainty_score":0.006268978},"labels":[],"label_agreement":null},{"id":"W2166044131","doi":"10.1172/jci15463","title":"Circulating levels of IGF-1 directly regulate bone growth and density","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":846,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Novo Nordisk; National Institutes of Health; Aarhus Universitet","keywords":"Endocrinology; Internal medicine; Bone growth; Protein subunit; Pathophysiology; Growth factor; Osteoporosis; Endocrine system; Chemistry; Biology; Receptor; Gene; Medicine; Biochemistry; Hormone","score_opus":0.12298556000926676,"score_gpt":0.33974059068095425,"score_spread":0.2167550306716875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166044131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9130557,0.051399056,0.009653409,0.0009254811,0.0002992749,0.000094044124,0.0010755822,0.00046598594,0.02303133],"genre_scores_gemma":[0.98086506,0.0072722966,0.003822837,0.00017770503,0.00008442063,0.00006129297,0.0002990994,0.00002007726,0.00739727],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99994993,0.000009315406,0.0000027137858,0.0000100261905,0.000017308628,0.000010744701],"domain_scores_gemma":[0.99993217,0.000014060537,0.000016108437,0.0000038601415,0.000011107919,0.00002275511],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009840174,0.00025958457,0.00016192858,0.00015922343,0.00007397494,0.000308827,0.00012334505,0.00017722255,0.0016385411],"category_scores_gemma":[0.00018654976,0.00006996064,0.000054263695,0.00008706702,0.00020108832,0.00010860022,0.00011432301,0.00031465056,0.0003019152],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020205874,0.0002640428,0.013690905,0.0003384881,0.000037522805,0.0004714507,0.00009346461,0.00017973455,0.85174394,0.0012341772,0.0017891377,0.12813643],"study_design_scores_gemma":[0.0005046493,0.0032257934,0.37318778,0.0002200017,0.00014749919,0.002477336,0.00028208425,0.0022031667,0.5391406,0.0021099064,0.07646621,0.00003497841],"about_ca_topic_score_codex":0.00056375837,"about_ca_topic_score_gemma":0.0007174778,"teacher_disagreement_score":0.0016385411,"about_ca_system_score_codex":0.00030156708,"about_ca_system_score_gemma":0.00014443412,"threshold_uncertainty_score":0.005481422},"labels":[],"label_agreement":null},{"id":"W2166355332","doi":"10.1172/jci45636","title":"Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pelvic floor disorders treatments","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; Welch Foundation; National Institute on Aging; National Institutes of Health; American Heart Association","keywords":"Fibulin; Extracellular matrix; Matricellular protein; Fibronectin; Matrix metalloproteinase; Downregulation and upregulation; Integrin; Cell biology; Elastic fiber; Proteases; Biology; Medicine; Pathology; Internal medicine; Biochemistry; Receptor; Enzyme","score_opus":0.07295887167957309,"score_gpt":0.3860493098195082,"score_spread":0.3130904381399351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166355332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9623084,0.013610071,0.010552844,0.0017990419,0.00024852707,0.00017323183,0.002987393,0.00055359566,0.0077668116],"genre_scores_gemma":[0.98126787,0.0061062174,0.0051657446,0.00052625535,0.000046645364,0.0002184562,0.00116299,0.000054572247,0.005451243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997279,0.00008036793,0.000022509957,0.00006409335,0.00005354812,0.000051587416],"domain_scores_gemma":[0.9997842,0.000021661554,0.000094202056,0.000022914055,0.000015831285,0.00006122822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032960615,0.00047652857,0.00028153302,0.0007438691,0.00022052268,0.00048212556,0.00018294569,0.00065153424,0.0033769193],"category_scores_gemma":[0.00031458246,0.00029973776,0.00034700226,0.000273994,0.00038180003,0.00023502421,0.0003468316,0.00088574,0.0004809244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032527158,0.0004099809,0.010556478,0.00033044413,0.00010496301,0.0017719334,0.00014889412,0.00029440998,0.9556245,0.0018547324,0.0019414066,0.023709586],"study_design_scores_gemma":[0.0010158092,0.008027885,0.35004726,0.0006598258,0.00064691954,0.035200097,0.001092198,0.0070076343,0.509846,0.0036714065,0.08263298,0.00015200196],"about_ca_topic_score_codex":0.00061777444,"about_ca_topic_score_gemma":0.0004513083,"teacher_disagreement_score":0.0033769193,"about_ca_system_score_codex":0.00025016337,"about_ca_system_score_gemma":0.0003026114,"threshold_uncertainty_score":0.0112969875},"labels":[],"label_agreement":null},{"id":"W2167612600","doi":"10.1172/jci27352","title":"Intestinal ABCA1 directly contributes to HDL biogenesis in vivo","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":513,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"ABCA1; Biogenesis; In vivo; Cholesterol; Reverse cholesterol transport; Biology; Chylomicron; Apolipoprotein B; Tangier disease; Endocrinology; Internal medicine; Chemistry; Lipoprotein; Cell biology; Biochemistry; Transporter; Medicine; Genetics; Very low-density lipoprotein","score_opus":0.05412170132786905,"score_gpt":0.3633503876367106,"score_spread":0.3092286863088416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167612600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860656,0.003998706,0.005096484,0.00093379593,0.00008563638,0.000031870783,0.0004664015,0.00025918413,0.0030622135],"genre_scores_gemma":[0.99266464,0.0012819482,0.0016271973,0.00023573542,0.000062346786,0.00003851668,0.0006275538,0.0000699001,0.0033920126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974984,0.000058997437,0.000015765292,0.000055878005,0.000049417056,0.00007004703],"domain_scores_gemma":[0.9995498,0.000105021274,0.00008580338,0.00008133879,0.000045895056,0.00013212339],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031590697,0.00033335088,0.00045714813,0.00035112211,0.00018112254,0.0007928337,0.00017890256,0.00044073962,0.003312498],"category_scores_gemma":[0.00044998692,0.0003302412,0.00026446645,0.00015266932,0.0003026345,0.00035467584,0.00038514094,0.0009848295,0.0010046967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010941427,0.00007668859,0.0017057244,0.00007962724,0.000010168763,0.00021118174,0.000026370608,0.000042657342,0.99165803,0.0003452012,0.00020662839,0.004543476],"study_design_scores_gemma":[0.00040298759,0.0010837956,0.0512669,0.000038760354,0.00016083501,0.0026406741,0.00012318672,0.0029895848,0.92704135,0.0008175069,0.013412522,0.000021851867],"about_ca_topic_score_codex":0.00044843103,"about_ca_topic_score_gemma":0.00034328445,"teacher_disagreement_score":0.003312498,"about_ca_system_score_codex":0.00030062153,"about_ca_system_score_gemma":0.00020413306,"threshold_uncertainty_score":0.0110813975},"labels":[],"label_agreement":null},{"id":"W2167793118","doi":"10.1172/jci17993","title":"Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":306,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Health Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Health Canada","keywords":"Chlamydia trachomatis; Tryptophan synthase; Biology; Chlamydiae; Trachoma; Microbiology; Pathogen; Serotype; Gene; Chlamydia; Virology; ATP synthase; Immunology; Genetics; Escherichia coli; Medicine; Pathology","score_opus":0.06918561307642289,"score_gpt":0.3615554809031053,"score_spread":0.2923698678266824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167793118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992836,0.00009468887,0.00022409446,0.000012152061,0.0000016607007,0.000007851978,0.00014611338,0.0000046273644,0.0002251237],"genre_scores_gemma":[0.99955016,0.000031638392,0.00020153429,0.000009030271,0.0000010929823,0.000004253432,0.00011653126,0.000002956726,0.00008279554],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99975926,0.000054342792,0.000030803425,0.00004898976,0.000037585116,0.00006911049],"domain_scores_gemma":[0.9994517,0.00020087455,0.00015202335,0.00006238609,0.00004933212,0.00008370998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002209836,0.00019889769,0.00015725938,0.0006454456,0.00018087799,0.0002998621,0.00012255742,0.00026252252,0.0013797272],"category_scores_gemma":[0.0010962146,0.00012593388,0.00019576708,0.00040322414,0.00025250696,0.00008333432,0.00021543796,0.00020624994,0.00016591202],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093010016,0.00008406389,0.39523494,0.000053933636,0.00006599062,0.00052306615,0.00045584977,0.0001025863,0.5911319,0.0001823285,0.00010073728,0.011134512],"study_design_scores_gemma":[0.000024261617,0.00040642754,0.9429429,0.000018645702,0.00007162599,0.0020220832,0.00036480027,0.0003846302,0.053051006,0.00010557346,0.00059474085,0.000013289198],"about_ca_topic_score_codex":0.0027682618,"about_ca_topic_score_gemma":0.00474237,"teacher_disagreement_score":0.0027682618,"about_ca_system_score_codex":0.00020234483,"about_ca_system_score_gemma":0.00016280562,"threshold_uncertainty_score":0.00550431},"labels":[],"label_agreement":null},{"id":"W2168279415","doi":"10.1172/jci77126","title":"Energy homeostasis targets chromosomal reconfiguration of the human GH1 locus","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; University of Manitoba","keywords":"Biology; Endocrinology; Internal medicine; Hyperinsulinemia; Energy homeostasis; Chromatin; Glucose homeostasis; Locus (genetics); Homeostasis; Insulin; Insulin resistance; Gene; Genetics; Obesity","score_opus":0.052866780544756874,"score_gpt":0.33037875594965604,"score_spread":0.2775119754048992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168279415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969079,0.0009965954,0.00088781206,0.00007551445,0.000011338435,0.000010370011,0.000116780175,0.00005335696,0.0009403515],"genre_scores_gemma":[0.99813324,0.0003588563,0.0005083817,0.000030889478,0.000005995164,0.000009176586,0.00019982479,0.000008177968,0.00074555975],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99995387,0.0000063855196,0.0000025510271,0.000014956801,0.000010198194,0.000012017716],"domain_scores_gemma":[0.9999603,0.000009024858,0.000013949901,0.00000406984,0.000002838568,0.000009751351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047257618,0.00013001038,0.00007420293,0.000091148715,0.00007371755,0.0001503535,0.000096253374,0.000112607166,0.0009445692],"category_scores_gemma":[0.00009989792,0.000077132274,0.00008553324,0.00005899966,0.0001964226,0.000063611726,0.00012364604,0.00022706998,0.00012881143],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019974464,0.000015029733,0.0012283522,0.00001382672,0.00000410832,0.00006110598,0.000013500475,0.000065730994,0.99474394,0.00006761396,0.000034684672,0.0035523945],"study_design_scores_gemma":[0.00005310493,0.0009914502,0.10685396,0.00001020675,0.000023686773,0.0014427442,0.00006499327,0.000617623,0.88525414,0.00018064433,0.004498927,0.000008625871],"about_ca_topic_score_codex":0.0004670755,"about_ca_topic_score_gemma":0.00078401197,"teacher_disagreement_score":0.0009445692,"about_ca_system_score_codex":0.00018014201,"about_ca_system_score_gemma":0.000121429985,"threshold_uncertainty_score":0.003159821},"labels":[],"label_agreement":null},{"id":"W2168597028","doi":"10.1172/jci64516","title":"Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":435,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Michael Smith Health Research BC","keywords":"GSK-3; Amyloid precursor protein secretase; Amyloid precursor protein; Senile plaques; GSK3B; Alzheimer's disease; BACE1-AS; Glycogen synthase; Gene isoform; Transgene; Biology; Cell biology; Pathogenesis; Phenotype; Neuropathology; Signal transduction; Tau protein; Neuroscience; Genetically modified mouse; Gene; Medicine; Biochemistry; Disease; Phosphorylation; Internal medicine; Immunology","score_opus":0.1440323869757492,"score_gpt":0.42070024730850736,"score_spread":0.27666786033275814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168597028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.977751,0.013571969,0.0022731966,0.0005451618,0.00023749073,0.00011216822,0.00078390737,0.00031639394,0.004408645],"genre_scores_gemma":[0.98621887,0.007157415,0.0016856226,0.00018167504,0.00004435919,0.00019232348,0.0008992392,0.000032260337,0.0035883125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998714,0.000020742495,0.000017737157,0.00002023191,0.00003219758,0.000037673235],"domain_scores_gemma":[0.9999174,0.000010101742,0.000024369741,0.000008271627,0.000011413876,0.000028439998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020233847,0.00047746862,0.00047641163,0.0003676987,0.00017744473,0.00032825238,0.00024683907,0.00031588922,0.0018472035],"category_scores_gemma":[0.0001635712,0.00016553103,0.00027001306,0.00029203863,0.0003267213,0.00020513046,0.00015708987,0.0009902597,0.0005019476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013162738,0.0004927942,0.00036652345,0.00027982306,0.000039865903,0.00007023458,0.00003963073,0.0001232847,0.9877528,0.00024606916,0.00064766814,0.008624954],"study_design_scores_gemma":[0.0007682899,0.0037230903,0.012933859,0.00005200468,0.00012413229,0.00050178554,0.0000912399,0.0016022519,0.9685744,0.00026010623,0.011348818,0.000020026582],"about_ca_topic_score_codex":0.00072399393,"about_ca_topic_score_gemma":0.0016140345,"teacher_disagreement_score":0.0018472035,"about_ca_system_score_codex":0.0003034151,"about_ca_system_score_gemma":0.00051138684,"threshold_uncertainty_score":0.0061795115},"labels":[],"label_agreement":null},{"id":"W2168964544","doi":"10.1172/jci57275","title":"Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":684,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Antagonism; Reverse cholesterol transport; Cholesterol; Regression; Biology; Cell biology; Chemistry; Medicine; Internal medicine; Endocrinology; Receptor; Lipoprotein; Mathematics; Statistics","score_opus":0.12790930240350054,"score_gpt":0.35610709569500604,"score_spread":0.2281977932915055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168964544","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98060775,0.002319308,0.008430961,0.0012606696,0.00021656057,0.00017806211,0.0015644195,0.001258085,0.0041642445],"genre_scores_gemma":[0.9671456,0.0028161916,0.01289657,0.00054169685,0.0001164738,0.000382578,0.0017269668,0.00029619268,0.014077871],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945897,0.000114400704,0.000064176704,0.00010044073,0.00012575439,0.00013633324],"domain_scores_gemma":[0.9995146,0.0000547414,0.00016981554,0.00005903454,0.000033660643,0.00016809678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005164458,0.0010283084,0.0006905412,0.0011843657,0.00046219258,0.00063435815,0.0004558581,0.0010838489,0.0037393493],"category_scores_gemma":[0.00030097453,0.0007357299,0.0005964749,0.00030511816,0.00079967204,0.00049973914,0.0003437177,0.0022892263,0.0014934615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001301843,0.0005622675,0.00024510387,0.00006304676,0.000021208016,0.00014882728,0.00004317396,0.00012389482,0.9937796,0.0005066542,0.0003326994,0.0028716414],"study_design_scores_gemma":[0.00072564016,0.0046560504,0.0054901615,0.00006009022,0.0001079914,0.001471654,0.00011071462,0.0034538188,0.97189,0.00077717635,0.011215995,0.000040736937],"about_ca_topic_score_codex":0.00060169824,"about_ca_topic_score_gemma":0.0012496779,"teacher_disagreement_score":0.0037393493,"about_ca_system_score_codex":0.0005225751,"about_ca_system_score_gemma":0.00053321815,"threshold_uncertainty_score":0.012509406},"labels":[],"label_agreement":null},{"id":"W2169338224","doi":"10.1172/jci32849","title":"Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Vagus Nerve Stimulation Research","field":"Neuroscience","cited_by":234,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation; McMaster University; Institut de France","keywords":"Vagus nerve; Tricyclic; Inflammation; Inflammatory bowel disease; Medicine; Colitis; Tonic (physiology); Monoamine neurotransmitter; Irritable bowel syndrome; Proinflammatory cytokine; Tricyclic antidepressant; Imipramine; Antidepressant; Internal medicine; Immunology; Pharmacology; Endocrinology; Disease; Serotonin; Pathology; Receptor; Stimulation; Hippocampus","score_opus":0.1671487793872885,"score_gpt":0.39573078579665344,"score_spread":0.22858200640936494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169338224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949763,0.0016000989,0.0010815436,0.00029959952,0.000046397414,0.000057694844,0.00049263577,0.00017761809,0.0012682213],"genre_scores_gemma":[0.991747,0.002187166,0.0023712928,0.00019763233,0.000021627238,0.0001589546,0.0006591273,0.00003258411,0.002624545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969375,0.00008930107,0.000031909552,0.000055841203,0.000068355854,0.00006084753],"domain_scores_gemma":[0.9997161,0.000025755953,0.00010140665,0.000024911442,0.000017073366,0.000114772214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025487103,0.00084718305,0.00047157402,0.0011196176,0.0002646685,0.00041952173,0.00023181524,0.00073926925,0.0019728604],"category_scores_gemma":[0.00023529168,0.00049937365,0.00033349235,0.00034900114,0.00035264803,0.00031258483,0.00027173897,0.0016343894,0.00048257897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014209355,0.000576001,0.001781864,0.00007698632,0.00003732563,0.00030678418,0.000059369075,0.00011684975,0.99209315,0.00016086789,0.00021988557,0.003149894],"study_design_scores_gemma":[0.0014018599,0.01572792,0.13864717,0.00021728741,0.00037957018,0.0048941756,0.0003886233,0.00815369,0.82242817,0.00084771245,0.006845385,0.00006833778],"about_ca_topic_score_codex":0.00066477695,"about_ca_topic_score_gemma":0.0014265731,"teacher_disagreement_score":0.0019728604,"about_ca_system_score_codex":0.00045283957,"about_ca_system_score_gemma":0.00018479672,"threshold_uncertainty_score":0.0065998435},"labels":[],"label_agreement":null},{"id":"W2170451911","doi":"10.1172/jci15506","title":"Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":266,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development","keywords":"Rolipram; Xylazine; Phosphodiesterase; Pentobarbital; Ketamine; Pharmacology; Endocrinology; Chemistry; Internal medicine; Anesthesia; Medicine; Enzyme; Biochemistry","score_opus":0.05860576188850777,"score_gpt":0.32529729899747234,"score_spread":0.2666915371089646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170451911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872958,0.0012273251,0.0066101365,0.00035804673,0.00010759635,0.00016595479,0.002291067,0.00033798773,0.0016060364],"genre_scores_gemma":[0.9688448,0.0024051496,0.011388774,0.00031368659,0.00006253578,0.000505637,0.002889502,0.0003030371,0.013287083],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995963,0.000054927135,0.00006418406,0.00013275791,0.00006961608,0.00008221089],"domain_scores_gemma":[0.9994987,0.000053163723,0.00022889508,0.000038359132,0.000024240053,0.00015666033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029276067,0.0012153086,0.00050705817,0.0013211305,0.00033853183,0.0003803993,0.00053538027,0.00084077514,0.0032720882],"category_scores_gemma":[0.0002200801,0.0007088519,0.00084805413,0.0003330869,0.0007634571,0.00042782142,0.00042012503,0.0015619091,0.0006647301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003719401,0.00009679739,0.00023085863,0.000033991557,0.000012854224,0.00010350791,0.000023650178,0.000063999796,0.99792117,0.00016914286,0.000054535318,0.0009174973],"study_design_scores_gemma":[0.0003323184,0.002045512,0.009596914,0.000041597836,0.00009937756,0.0010460528,0.00011167918,0.0015090227,0.9797086,0.00014347701,0.005342149,0.00002330536],"about_ca_topic_score_codex":0.00095896714,"about_ca_topic_score_gemma":0.0018168463,"teacher_disagreement_score":0.0032720882,"about_ca_system_score_codex":0.00061634945,"about_ca_system_score_gemma":0.00039877585,"threshold_uncertainty_score":0.010946214},"labels":[],"label_agreement":null},{"id":"W2171141151","doi":"10.1172/jci63735","title":"Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"Kitasato University; Astellas Foundation for Research on Metabolic Disorders; Yasuda Memorial Medical Foundation; Cosmetology Research Foundation; Astellas Pharma; Ono Medical Research Foundation; Ministry of Education, Culture, Sports, Science and Technology; Uehara Memorial Foundation; Fukuoka Foundation for Sound Health; Sumitomo Foundation; Naito Foundation","keywords":"YAP1; Hippo signaling pathway; Biology; Embryonic stem cell; Cell biology; Progenitor cell; Keratinocyte; Cancer research; Mutant; Signal transduction; Stem cell; Cell culture; Genetics; Transcription factor","score_opus":0.08975450023300949,"score_gpt":0.39451814850092626,"score_spread":0.3047636482679168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171141151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815439,0.0014880415,0.0064778896,0.00038756957,0.00009112551,0.00015528062,0.0052463952,0.0007114587,0.0038982818],"genre_scores_gemma":[0.9614767,0.0021854625,0.007596268,0.00022994648,0.00004679244,0.00040545527,0.005032099,0.0004322955,0.022594986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99962926,0.0000497282,0.000037430003,0.00013540467,0.00009626504,0.00005190282],"domain_scores_gemma":[0.9995778,0.000044170843,0.0001534276,0.000034565895,0.000021869886,0.0001680869],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024927175,0.0011258391,0.00039575133,0.0021214797,0.00042113024,0.00041109222,0.00043666497,0.0009942013,0.0052835965],"category_scores_gemma":[0.00019937409,0.00055109465,0.00049771776,0.00035250364,0.0005431941,0.00023482305,0.00054514204,0.0014103727,0.0014139593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024265179,0.00007816081,0.000545079,0.000036277226,0.000013592159,0.00050213886,0.000040114042,0.000071288014,0.99650526,0.00026905767,0.00017127757,0.0015251291],"study_design_scores_gemma":[0.00038202264,0.001509611,0.04238497,0.00011151846,0.00013290082,0.015913507,0.00018282841,0.0033925783,0.9196209,0.00051037857,0.015801763,0.00005705727],"about_ca_topic_score_codex":0.0007646621,"about_ca_topic_score_gemma":0.0013272214,"teacher_disagreement_score":0.0052835965,"about_ca_system_score_codex":0.0003835767,"about_ca_system_score_gemma":0.00028719037,"threshold_uncertainty_score":0.0176754},"labels":[],"label_agreement":null},{"id":"W2171559522","doi":"10.1172/jci16233","title":"Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":196,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Health Canada; University of Ottawa","funders":"Université de Montréal; Canadian Institutes of Health Research; Ontario HIV Treatment Network; Canadian Foundation for AIDS Research; Doris Duke Charitable Foundation","keywords":"Biology; Virology; Immune system; Vesicular stomatitis virus; Apoptosis; Viral replication; Programmed cell death; Virus; Cell biology; Immunology; Genetics","score_opus":0.06288228138622284,"score_gpt":0.35845517642185576,"score_spread":0.2955728950356329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171559522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989147,0.0004121814,0.00029325593,0.000037042344,0.0000053402578,0.000005096293,0.000042159616,0.000017934814,0.00027216077],"genre_scores_gemma":[0.9993186,0.00014548791,0.00014228068,0.000018338686,0.000014722469,0.0000041720305,0.00010157662,0.000006154869,0.00024864724],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99975663,0.000064437365,0.000035910212,0.000047183643,0.000048064267,0.000047784193],"domain_scores_gemma":[0.9989184,0.00022689559,0.00052545423,0.00008344348,0.00006203394,0.00018376159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026291126,0.0006504445,0.0003507043,0.00063570694,0.00027049077,0.0003217318,0.0003239611,0.0006613075,0.0020148158],"category_scores_gemma":[0.00081403495,0.0002190927,0.00026235037,0.0002506528,0.0007207714,0.00025946827,0.00038810069,0.0005196644,0.00040645723],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006458346,0.0005258229,0.26571134,0.00027936767,0.00030277536,0.07273269,0.0004451832,0.00046647523,0.6287863,0.0009751438,0.0006810647,0.02263555],"study_design_scores_gemma":[0.00024761076,0.0031479744,0.65264297,0.0000590192,0.00020668756,0.2945148,0.00036977834,0.0011402725,0.04525252,0.00059597444,0.0017809503,0.000041439187],"about_ca_topic_score_codex":0.00028300294,"about_ca_topic_score_gemma":0.00025230795,"teacher_disagreement_score":0.0020148158,"about_ca_system_score_codex":0.00014693732,"about_ca_system_score_gemma":0.0001248918,"threshold_uncertainty_score":0.0067402124},"labels":[],"label_agreement":null},{"id":"W2171752682","doi":"10.1172/jci38454","title":"Targeted electrode-based modulation of neural circuits for depression","year":2009,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":538,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; Emory University; Woodruff Foundation","keywords":"Neurochemical; Neuromodulation; Neuroscience; Neuroimaging; Deep brain stimulation; Conceptualization; Biological neural network; Depression (economics); Psychology; Medicine; Stimulation; Computer science; Artificial intelligence","score_opus":0.20780268587559758,"score_gpt":0.4536645806105857,"score_spread":0.2458618947349881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171752682","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029099913,0.9974776,0.000431868,0.0001395747,0.00013157702,0.000008477515,0.000010532361,0.000011434275,0.0014980051],"genre_scores_gemma":[0.0022519703,0.99556386,0.00057234924,0.00017641058,0.00012445271,0.000011967956,0.000024536332,0.0000022079814,0.0012722497],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99990404,0.000017243563,0.000011277286,0.000021061553,0.00003784559,0.0000083974965],"domain_scores_gemma":[0.9999145,0.00004583144,0.000012916199,0.0000041339777,0.000016807417,0.0000058118353],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039172254,0.0007752724,0.0010809895,0.0012530491,0.00017481399,0.0005566319,0.0009243015,0.0011334141,0.002988028],"category_scores_gemma":[0.00033338714,0.00024588048,0.0004376422,0.0011257377,0.00036842452,0.00072724186,0.00038100395,0.0009998365,0.002875384],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000950823,0.0001261694,0.0001413699,0.008890968,0.00009804041,0.0004915604,0.00005023049,0.00046144848,0.010318676,0.0035391129,0.016586855,0.95920044],"study_design_scores_gemma":[0.00009664351,0.00033515517,0.0019876377,0.0030357148,0.00018758397,0.0057667107,0.000097789336,0.00041554385,0.004757884,0.004931901,0.9783432,0.000044156455],"about_ca_topic_score_codex":0.00061174395,"about_ca_topic_score_gemma":0.0014276393,"teacher_disagreement_score":0.002988028,"about_ca_system_score_codex":0.00037757168,"about_ca_system_score_gemma":0.0003330682,"threshold_uncertainty_score":0.009995997},"labels":[],"label_agreement":null},{"id":"W2171932269","doi":"10.1172/jci41940","title":"Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; University of Toronto; Joslin Diabetes Center","keywords":"Insulin resistance; Skeletal muscle; Internal medicine; Endocrinology; Serum response factor; Insulin receptor; Insulin; Biology; Coactivator; Actin cytoskeleton; Downregulation and upregulation; Gene expression; Medicine; Transcription factor; Cytoskeleton; Cell; Gene; Genetics","score_opus":0.06425576819263791,"score_gpt":0.34681984230249724,"score_spread":0.28256407410985934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171932269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931178,0.0029324575,0.002225243,0.00006479792,0.00001424539,0.0000134779675,0.0006439616,0.00006517162,0.0009229165],"genre_scores_gemma":[0.99118245,0.0016466494,0.0029930128,0.000074163654,0.000014723928,0.000046538564,0.0017650644,0.00002438294,0.002252919],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998312,0.000026376363,0.000014233921,0.000060342594,0.000044076616,0.000023808068],"domain_scores_gemma":[0.99993825,0.000008532356,0.000022078546,0.000008772018,0.0000070488845,0.000015302843],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022978589,0.00021028452,0.00019299185,0.0005609976,0.00009410703,0.0002572153,0.0000933395,0.00022300455,0.0012791029],"category_scores_gemma":[0.00009314904,0.00012881008,0.00021993765,0.00027183822,0.0001700706,0.000082803046,0.000109558205,0.00021410771,0.00030193015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002645133,0.000018975034,0.001656104,0.000026498734,0.000010705905,0.000066466644,0.000017930814,0.000021225487,0.9961047,0.000055610966,0.00004184877,0.0017154567],"study_design_scores_gemma":[0.00011725277,0.0010289144,0.24628204,0.000045643235,0.00010294379,0.004839289,0.00016917182,0.0013447456,0.7380133,0.00023437239,0.0078030173,0.000019295567],"about_ca_topic_score_codex":0.00033456428,"about_ca_topic_score_gemma":0.00051898864,"teacher_disagreement_score":0.0012791029,"about_ca_system_score_codex":0.00013711935,"about_ca_system_score_gemma":0.00007746324,"threshold_uncertainty_score":0.004279077},"labels":[],"label_agreement":null},{"id":"W2171980060","doi":"10.1172/jci45523","title":"GLI3 repressor controls functional development of the mouse ureter","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Kidney Foundation of Canada","keywords":"Repressor; GLI3; Ureter; Biology; Anatomy; Medicine; Internal medicine; Urology; Genetics; Gene; Transcription factor","score_opus":0.08275085066315363,"score_gpt":0.3133878142772442,"score_spread":0.23063696361409058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171980060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98483825,0.0013970531,0.0063204793,0.00018507375,0.000039272752,0.00005185823,0.0014902363,0.0005942931,0.005083435],"genre_scores_gemma":[0.98530257,0.00058324117,0.003024699,0.00009331485,0.000010485134,0.000068178924,0.0012863156,0.00019142745,0.009439807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963856,0.000034494726,0.00003216329,0.000086334454,0.00012473894,0.00008360276],"domain_scores_gemma":[0.99972266,0.000023114782,0.00010246607,0.00003502398,0.000020743244,0.00009589906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019262197,0.0004216372,0.00020140434,0.0007602915,0.00022887671,0.00043314585,0.0003725702,0.00050314225,0.00234276],"category_scores_gemma":[0.00014485796,0.00042127562,0.00040467858,0.00018000964,0.00041384008,0.00018256652,0.00037438105,0.0007996286,0.0011431583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008428882,0.000011915305,0.00015936815,0.000010572878,0.000002668194,0.00006731143,0.000012216331,0.00004411706,0.99857783,0.00028616592,0.00003728872,0.00070623145],"study_design_scores_gemma":[0.00004072091,0.00015516268,0.0077947215,0.000011949752,0.000017234397,0.0007120201,0.00003172761,0.0014716218,0.98450655,0.0001791739,0.0050716875,0.00000748739],"about_ca_topic_score_codex":0.0010558073,"about_ca_topic_score_gemma":0.001678988,"teacher_disagreement_score":0.00234276,"about_ca_system_score_codex":0.0006887725,"about_ca_system_score_gemma":0.000351834,"threshold_uncertainty_score":0.0078372955},"labels":[],"label_agreement":null},{"id":"W2173898107","doi":"10.1172/jci85004","title":"cAMP-independent effects of GLP-1 on β cells","year":2015,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta; Canadian Diabetes Association","keywords":"Incretin; Glucagon-like peptide-1; Insulin; Postprandial; Endocrinology; Internal medicine; Secretion; Diabetes mellitus; Islet; Hormone; Type 2 diabetes; Biology; Medicine","score_opus":0.08185036978054291,"score_gpt":0.36278020730948857,"score_spread":0.2809298375289456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2173898107","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009070524,0.046015494,0.0009637247,0.8621092,0.052014593,0.0000645558,0.00016894253,0.00025284238,0.029340127],"genre_scores_gemma":[0.105592,0.058943376,0.0012602275,0.65237284,0.1517351,0.00017359018,0.00015293997,0.000050739676,0.02971922],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930525,0.00018835417,0.00006351606,0.0000793579,0.0002772178,0.00008635811],"domain_scores_gemma":[0.9986401,0.00074639416,0.0001405965,0.00012129842,0.0002014582,0.00015018061],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007537517,0.0005280121,0.00046240693,0.00032728678,0.0007450006,0.0011662234,0.00058935763,0.0064206966,0.0044177426],"category_scores_gemma":[0.003262913,0.00023857898,0.000549967,0.00020126441,0.0014655349,0.00083587924,0.0006124107,0.0076014837,0.0067070643],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008914494,0.00018968419,0.0017030208,0.00059503113,0.000057939127,0.014276268,0.00024763134,0.00021258293,0.022489622,0.009623689,0.81610024,0.13361293],"study_design_scores_gemma":[0.00028025324,0.00029993808,0.0024350586,0.00025985518,0.000025986668,0.011722234,0.00020670351,0.00046642657,0.010054528,0.0108834505,0.9633275,0.00003802612],"about_ca_topic_score_codex":0.00044928587,"about_ca_topic_score_gemma":0.0007116592,"teacher_disagreement_score":0.0064206966,"about_ca_system_score_codex":0.0013206368,"about_ca_system_score_gemma":0.0004219788,"threshold_uncertainty_score":0.014778852},"labels":[],"label_agreement":null},{"id":"W2173989824","doi":"10.1172/jci85002","title":"Memory or amnesia: the dilemma of stem cell therapy in muscular dystrophies","year":2015,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Induced pluripotent stem cell; Muscular dystrophy; Genetic enhancement; Duchenne muscular dystrophy; Bioinformatics; Biology; Stem cell; Gene delivery; Myocyte; Neuroscience; Medicine; Gene; Genetics; Cell biology; Embryonic stem cell","score_opus":0.1089269614849972,"score_gpt":0.36231449860263193,"score_spread":0.25338753711763473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2173989824","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009924828,0.0074104588,0.00035498137,0.972128,0.01779103,0.000009858929,0.000012746132,0.00003758689,0.0012628735],"genre_scores_gemma":[0.017738547,0.014098025,0.0007378469,0.8670083,0.09490793,0.000052731735,0.000020466223,0.000029023306,0.0054071164],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980142,0.0009073404,0.00026987604,0.0001846694,0.0004808061,0.00014320425],"domain_scores_gemma":[0.9921814,0.0059867064,0.00029006807,0.00028259034,0.0008313498,0.0004279412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004525597,0.00059513585,0.001031737,0.00040737365,0.0016712252,0.0021316297,0.0015891258,0.022196049,0.0026019586],"category_scores_gemma":[0.018272882,0.00031619897,0.00094434636,0.00027540303,0.0049974453,0.0048277415,0.0012800132,0.02461855,0.002494953],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001866238,0.00014207627,0.0007493046,0.00031706018,0.000039562943,0.0078994855,0.00047892923,0.00016181298,0.00086068356,0.019091964,0.89308137,0.07699108],"study_design_scores_gemma":[0.00030812042,0.0004487339,0.0007686951,0.0006028323,0.00006706426,0.020721512,0.00083803595,0.0008591867,0.0012992759,0.048236243,0.925758,0.000092299146],"about_ca_topic_score_codex":0.0004955695,"about_ca_topic_score_gemma":0.0007247226,"teacher_disagreement_score":0.022196049,"about_ca_system_score_codex":0.0020212424,"about_ca_system_score_gemma":0.0013751312,"threshold_uncertainty_score":0.023933947},"labels":[],"label_agreement":null},{"id":"W2177810905","doi":"10.1172/jci83178","title":"A collagen VI–dependent pathogenic mechanism for Hirschsprung’s disease","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital gastrointestinal and neural anomalies","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Génome Québec; Université du Québec à Montréal; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Neural crest; Extracellular matrix; Fibronectin; Collagen VI; Hirschsprung's disease; Downregulation and upregulation; Enteric nervous system; Cell biology; Biology; Cell migration; Pathology; Cancer research; Immunology; Disease; Medicine; Cell; Gene; Endocrinology; Genetics","score_opus":0.16995113379342575,"score_gpt":0.38243286430072965,"score_spread":0.2124817305073039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2177810905","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909977,0.002387055,0.004015395,0.00016653843,0.000052951174,0.000039987943,0.0003194516,0.00012556734,0.0018953902],"genre_scores_gemma":[0.99432266,0.001516087,0.002534675,0.00005546903,0.000021483847,0.000018827464,0.00022459283,0.000011408897,0.0012947817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998902,0.000024910078,0.000010858439,0.000027741644,0.00002975963,0.000016520598],"domain_scores_gemma":[0.9999062,0.000015919217,0.00004053798,0.00000888623,0.0000052715086,0.00002326704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001297618,0.0005328381,0.00017566684,0.00036767893,0.0001378012,0.00018423988,0.00018944194,0.00037150495,0.0012057784],"category_scores_gemma":[0.00013512658,0.000107034844,0.00018356356,0.00011170506,0.00032331195,0.0001470325,0.00029968147,0.0003640085,0.0002596618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000132403,0.000031113665,0.002247032,0.000051702318,0.000008915949,0.0020679922,0.000022307726,0.000046193512,0.99224406,0.00036711607,0.00007793851,0.0027032914],"study_design_scores_gemma":[0.00013311204,0.0019171754,0.12053496,0.000082446466,0.00014930948,0.060710985,0.00018779201,0.002306497,0.79959494,0.0007209549,0.013625766,0.00003612976],"about_ca_topic_score_codex":0.00017034018,"about_ca_topic_score_gemma":0.00021641506,"teacher_disagreement_score":0.0012057784,"about_ca_system_score_codex":0.0001223728,"about_ca_system_score_gemma":0.0001150427,"threshold_uncertainty_score":0.0040336847},"labels":[],"label_agreement":null},{"id":"W2256023856","doi":"10.1172/jci80937","title":"TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; University of Texas MD Anderson Cancer Center; Directorate for Biological Sciences; George Washington University; American Cancer Society; U.S. Department of Veterans Affairs; National Cancer Institute; National Institutes of Health","keywords":"Beckwith–Wiedemann syndrome; CTCF; Medicine; Spectrin; Biology; Cancer research; Immunology; Genetics; Cell; Gene; Transcription factor","score_opus":0.030103862795979115,"score_gpt":0.31492420656648573,"score_spread":0.28482034377050663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2256023856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995742,0.0007775666,0.0020076355,0.00006885709,0.000019245434,0.000016007361,0.00034026793,0.00012380489,0.00090448116],"genre_scores_gemma":[0.9972199,0.0004582187,0.0010630207,0.00003137137,0.00000537423,0.0000120528275,0.00030930765,0.000012950518,0.00088783464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999938,0.000009332982,0.0000075313847,0.000018068473,0.000017406965,0.000009645299],"domain_scores_gemma":[0.9999304,0.0000093287645,0.000027378888,0.000004705978,0.000003319672,0.000024847328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006276458,0.00049540604,0.00016558582,0.0004443954,0.00014882273,0.00013982128,0.00009598692,0.00023809818,0.0014485401],"category_scores_gemma":[0.000108632026,0.00013691671,0.00021793348,0.00019405062,0.00026282127,0.0000664271,0.00019063022,0.0002854488,0.0002447209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008449672,0.000016988024,0.0029650931,0.00003023773,0.000017184895,0.0025651762,0.000027106582,0.00009665698,0.99156696,0.00024317531,0.000098552555,0.002288377],"study_design_scores_gemma":[0.00011787443,0.00047449965,0.120164976,0.000041608473,0.00015171214,0.055033296,0.00013850999,0.0031461597,0.811816,0.0005836685,0.00830307,0.000028594193],"about_ca_topic_score_codex":0.0006645816,"about_ca_topic_score_gemma":0.0012427114,"teacher_disagreement_score":0.0014485401,"about_ca_system_score_codex":0.00013438016,"about_ca_system_score_gemma":0.00016419892,"threshold_uncertainty_score":0.0048458576},"labels":[],"label_agreement":null},{"id":"W2303852857","doi":"10.1172/jci82771","title":"Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":476,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; University of British Columbia; Canadian Blood Services","keywords":"Chimeric antigen receptor; Immunology; Antigen; Immunotherapy; Human leukocyte antigen; Transplantation; Immune system; Cell therapy; Adoptive cell transfer; Major histocompatibility complex; Biology; Graft-versus-host disease; T cell; Medicine; Stem cell; Cell biology","score_opus":0.10537970307624715,"score_gpt":0.3739260898684617,"score_spread":0.26854638679221454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2303852857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9308006,0.0071739526,0.0548041,0.00038078672,0.00029049936,0.00040879947,0.0002823237,0.0007336018,0.0051252767],"genre_scores_gemma":[0.9795344,0.0018945996,0.014840607,0.00022813698,0.000066808556,0.00014457921,0.00035418858,0.00004087841,0.0028959422],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997614,0.000063803374,0.000015824615,0.00005079233,0.000059107377,0.000049085924],"domain_scores_gemma":[0.9999409,0.000013574152,0.000013430102,0.000011384976,0.00000936993,0.000011337086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003262628,0.00038324317,0.0003330088,0.00028371965,0.00012214652,0.0003561421,0.00022817533,0.00049189274,0.0013501768],"category_scores_gemma":[0.000153015,0.000092959766,0.0003394854,0.00015870671,0.00025897694,0.00021669154,0.00021101942,0.00092796615,0.00038972386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016618,0.00018350576,0.000336318,0.00007476154,0.00001384096,0.00011081023,0.000034522618,0.00043221706,0.9860745,0.0008106382,0.00019423002,0.011568443],"study_design_scores_gemma":[0.00018520876,0.0022168711,0.0012342817,0.000021194463,0.00007446376,0.0011832431,0.00004146446,0.0046593435,0.968056,0.00033149196,0.021981733,0.000014732194],"about_ca_topic_score_codex":0.00019628425,"about_ca_topic_score_gemma":0.00027529066,"teacher_disagreement_score":0.0013501768,"about_ca_system_score_codex":0.00013799027,"about_ca_system_score_gemma":0.00026189125,"threshold_uncertainty_score":0.004516721},"labels":[],"label_agreement":null},{"id":"W2326151669","doi":"10.1172/jci80205","title":"Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Hospital for Sick Children","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Osteoarthritis; Hedgehog; Catenin; Knee Joint; Medicine; Biology; Chemistry; Cell biology; Bioinformatics; Wnt signaling pathway; Pathology; Signal transduction; Surgery; Alternative medicine","score_opus":0.08588918283437016,"score_gpt":0.3335680901519088,"score_spread":0.24767890731753864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2326151669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9798783,0.013774071,0.0024010018,0.00015827731,0.000070793685,0.000055768127,0.00021141158,0.00011351738,0.0033368065],"genre_scores_gemma":[0.9920426,0.004159546,0.0009976024,0.00006619352,0.000012519481,0.000031129723,0.00025173213,0.000008132609,0.0024305924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987924,0.000019817146,0.000019648644,0.000015767666,0.00003924566,0.0000262867],"domain_scores_gemma":[0.99996626,0.0000042743673,0.000009281693,0.000004531411,0.0000043629675,0.000011231212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013324457,0.00027798352,0.00022113622,0.00022226054,0.00010486818,0.000203894,0.00013977928,0.00017061913,0.00067195855],"category_scores_gemma":[0.00008147635,0.00014448288,0.00025211726,0.00011971542,0.00016444085,0.000106133244,0.0001507957,0.0003190676,0.00018260413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023931087,0.000050457504,0.00028905354,0.00011639591,0.000016075102,0.000076364224,0.000013054241,0.000053109972,0.9937943,0.00014006406,0.00008378759,0.0051279548],"study_design_scores_gemma":[0.000074275886,0.0011155003,0.0071219294,0.000016507303,0.000063029016,0.00046243056,0.00003047913,0.0006317833,0.9844624,0.00009102269,0.005924728,0.000005965683],"about_ca_topic_score_codex":0.0007784379,"about_ca_topic_score_gemma":0.0016390574,"teacher_disagreement_score":0.0007784379,"about_ca_system_score_codex":0.00018036907,"about_ca_system_score_gemma":0.00021838736,"threshold_uncertainty_score":0.0022479296},"labels":[],"label_agreement":null},{"id":"W2414532145","doi":"10.1172/jci85830","title":"Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":289,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; Japan Society for the Promotion of Science; National Health and Medical Research Council; Medical Research Council; Robert H. Lurie Comprehensive Cancer Center; National Heart, Lung, and Blood Institute; Northwestern University; University of Wisconsin-Madison; Mallinckrodt Pharmaceuticals; Research to Prevent Blindness; National Institutes of Health; National Cancer Institute; National University of Singapore; March of Dimes Foundation","keywords":"Trabecular meshwork; Biology; Glaucoma; Phenotype; Haploinsufficiency; Schlemm's canal; Loss function; Genetics; Gene; Cell biology; Neuroscience","score_opus":0.03709722069796974,"score_gpt":0.3168550079633498,"score_spread":0.2797577872653801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414532145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99815,0.00056502863,0.0004897455,0.00004833591,0.000006037833,0.000011064575,0.0001438696,0.000029054796,0.0005569133],"genre_scores_gemma":[0.99929786,0.00016547547,0.00030724166,0.0000135109385,0.000008910304,0.0000021933856,0.00006517852,0.000005633422,0.00013405904],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99983597,0.00002141226,0.000022073633,0.000051330473,0.00004552692,0.000023666471],"domain_scores_gemma":[0.99970156,0.00008751073,0.00014285141,0.000012553321,0.000013895139,0.000041543717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012766018,0.0005529997,0.00028968183,0.0006228971,0.00025000316,0.00021027609,0.00016459222,0.00030034935,0.0011787163],"category_scores_gemma":[0.00058933627,0.0001326748,0.00013955648,0.00041305143,0.00061607285,0.00016505443,0.0003145792,0.00026921052,0.00018566463],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013012898,0.00013520081,0.30708113,0.00026358786,0.00021103,0.12064666,0.00077105005,0.00077514973,0.53361434,0.0018724005,0.0010248843,0.032303266],"study_design_scores_gemma":[0.00012000135,0.00049322506,0.6254529,0.000045977205,0.00023999446,0.31592715,0.0003760412,0.0016913576,0.051577967,0.00073864753,0.003303101,0.00003366421],"about_ca_topic_score_codex":0.00068145356,"about_ca_topic_score_gemma":0.000898164,"teacher_disagreement_score":0.0011787163,"about_ca_system_score_codex":0.00017780192,"about_ca_system_score_gemma":0.00016985006,"threshold_uncertainty_score":0.003943205},"labels":[],"label_agreement":null},{"id":"W2416666529","doi":"10.1172/jci83005","title":"Metabolic regulation of immune responses: therapeutic opportunities","year":2016,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Trinity College Dublin; Science Foundation Ireland","keywords":"Immune system; Biology; Cell metabolism; Metabolic pathway; Cell biology; Signal transduction; Immunity; Metabolism; Cellular metabolism; Cell; Metabolic control analysis; T cell; Immunology; Biochemistry; Biotechnology","score_opus":0.26778424335156414,"score_gpt":0.42244207998477895,"score_spread":0.1546578366332148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2416666529","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016421346,0.9977392,0.00020383633,0.00055002625,0.0003441955,0.0000041867315,0.000009260693,0.00000870791,0.0009763232],"genre_scores_gemma":[0.001467769,0.9967134,0.00031254452,0.0003258931,0.00042196712,0.000008736768,0.000021577895,0.0000021238852,0.0007259175],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998497,0.000034536413,0.000018355275,0.000024620795,0.00005096806,0.000021812108],"domain_scores_gemma":[0.9997967,0.00008962288,0.000024947283,0.000008106283,0.000051771698,0.000028954539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053705904,0.000668755,0.0011541619,0.0014856375,0.00026381342,0.0010370372,0.0007024254,0.0013840457,0.0036126939],"category_scores_gemma":[0.0005354413,0.00018218604,0.00045293392,0.00092347135,0.00049129647,0.0012999399,0.0007454022,0.0021962882,0.001591366],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001200956,0.00013561909,0.00017284337,0.008709581,0.000055151937,0.00040423407,0.000074294345,0.0003286903,0.0040065977,0.007826166,0.024804914,0.9533619],"study_design_scores_gemma":[0.000024460804,0.0001673778,0.00057990063,0.002721667,0.000063393214,0.0022714878,0.00007363721,0.00013393402,0.00093037385,0.0041920105,0.9888222,0.000019441835],"about_ca_topic_score_codex":0.00033961216,"about_ca_topic_score_gemma":0.00083408464,"teacher_disagreement_score":0.0036126939,"about_ca_system_score_codex":0.00050168496,"about_ca_system_score_gemma":0.0006867327,"threshold_uncertainty_score":0.012085676},"labels":[],"label_agreement":null},{"id":"W2461967278","doi":"10.1172/jci84767","title":"Truncated netrin-1 contributes to pathological vascular permeability in diabetic retinopathy","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; Polytechnique Montréal; McGill University; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Alcon Research Institute; Canadian Institutes of Health Research; Université de Montréal; Killam Trusts; Multiple Sclerosis Society; Fonds de Recherche du Québec - Santé; Multiple Sclerosis Society of Canada; Canadian Diabetes Association; Natural Sciences and Engineering Research Council of Canada; Foundation Fighting Blindness","keywords":"Vascular permeability; Diabetic retinopathy; Netrin; Retinal; Retina; Medicine; Angiogenesis; Retinopathy; Diabetes mellitus; Ophthalmology; Pathology; Internal medicine; Biology; Endocrinology; Receptor; Neuroscience; Axon guidance","score_opus":0.12461586084798476,"score_gpt":0.3664707907720131,"score_spread":0.24185492992402835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2461967278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942946,0.0033441996,0.0010616782,0.00013002171,0.000026588492,0.00001530073,0.000091552836,0.000035784116,0.0010002634],"genre_scores_gemma":[0.99764305,0.0010170916,0.0003899606,0.00005228015,0.000010090538,0.000006829892,0.000085924956,0.0000059100803,0.00078880653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999403,0.000013988601,0.0000070837796,0.000011956302,0.000014367935,0.000012264913],"domain_scores_gemma":[0.9998826,0.000011809148,0.000044556724,0.000008871541,0.000010027734,0.000042113945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014802693,0.00027900125,0.00025698903,0.000209992,0.00014243442,0.00023331688,0.00016121588,0.00032651235,0.0012415189],"category_scores_gemma":[0.00018222477,0.00011156518,0.00018472696,0.00008780424,0.00020505773,0.00019715418,0.00021361058,0.00055826973,0.00023606716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014718535,0.00010213132,0.001606696,0.00010562807,0.000020776522,0.0008667488,0.000036949175,0.00010839015,0.99068516,0.00031289132,0.00013599398,0.0045467927],"study_design_scores_gemma":[0.00029409456,0.002141626,0.13500158,0.000067128414,0.0002845853,0.013960408,0.00021000562,0.005394499,0.8315938,0.0014828711,0.009538774,0.000030456296],"about_ca_topic_score_codex":0.00031424765,"about_ca_topic_score_gemma":0.00025243353,"teacher_disagreement_score":0.0012415189,"about_ca_system_score_codex":0.00031132827,"about_ca_system_score_gemma":0.00009953725,"threshold_uncertainty_score":0.0041532516},"labels":[],"label_agreement":null},{"id":"W2478556254","doi":"10.1172/jci85939","title":"Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Leonard M. Miller School of Medicine; Institute of Genetics; National Institutes of Health; Waldemar von Frenckells Stiftelse; Novo Nordisk Fonden; Svenska Kulturfonden; Deutsche Forschungsgemeinschaft; American Heart Association; Halpin Foundation; University of Miami; Folkhälsanin Tutkimussäätiö; Wilhelm och Else Stockmanns Stiftelse; Nephcure Foundation; Samfundet Folkhälsan; F. Hoffmann-La Roche; University of Michigan; Novo Nordisk","keywords":"Podocyte; ABCA1; Albuminuria; Cholesterol; Endocrinology; Internal medicine; Medicine; Tumor necrosis factor alpha; Glomerulosclerosis; Kidney; Chemistry; Biochemistry; Transporter; Proteinuria","score_opus":0.058585559979733956,"score_gpt":0.3724486632723426,"score_spread":0.31386310329260864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2478556254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940767,0.0031891125,0.0014723549,0.00010114069,0.00003820544,0.000029886725,0.00015537514,0.000049733575,0.00088751776],"genre_scores_gemma":[0.99631256,0.0011640037,0.0009861785,0.000047666334,0.000026785787,0.00002853171,0.0002704523,0.000007230517,0.0011566351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997267,0.000055895045,0.00003128674,0.00006495989,0.00006273299,0.000058342343],"domain_scores_gemma":[0.9998548,0.00001446611,0.00004185149,0.000024316867,0.000015528738,0.000049073333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023282063,0.00042442838,0.000375763,0.00023456171,0.00020101585,0.00035489147,0.00013053881,0.00021909334,0.0013523573],"category_scores_gemma":[0.00015470627,0.00015519798,0.00029500716,0.00018885524,0.0002897484,0.00020233018,0.00023917298,0.0007196749,0.00042717025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046666947,0.0000879508,0.0018825452,0.00010075755,0.000014777632,0.0002149937,0.000032233267,0.000030651023,0.99489826,0.00003873256,0.00006846755,0.0021639022],"study_design_scores_gemma":[0.00020696233,0.0016149709,0.040465686,0.000031643227,0.00008303047,0.0038629444,0.00013216528,0.0014089908,0.947672,0.00011767979,0.0043938914,0.000010069464],"about_ca_topic_score_codex":0.0003819857,"about_ca_topic_score_gemma":0.0007897346,"teacher_disagreement_score":0.0013523573,"about_ca_system_score_codex":0.00023186806,"about_ca_system_score_gemma":0.0001824642,"threshold_uncertainty_score":0.0045241117},"labels":[],"label_agreement":null},{"id":"W2493933098","doi":"10.1172/jci61608","title":"A tribute to Ralph M. Steinman","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Tribute; Art; Art history","score_opus":0.12914888872555097,"score_gpt":0.35347334292773963,"score_spread":0.22432445420218866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2493933098","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019120012,0.012203582,0.00044509873,0.79064065,0.1840972,0.000019565507,0.000074967786,0.00013035024,0.012197398],"genre_scores_gemma":[0.0059726243,0.015764363,0.001370995,0.7436019,0.087871596,0.00008261702,0.00014305481,0.00036051957,0.14483228],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.994871,0.00101433,0.00024152352,0.0010925096,0.002216615,0.00056412205],"domain_scores_gemma":[0.98549545,0.0026091347,0.00044039413,0.0006149421,0.0053577176,0.005482391],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005307236,0.0012220849,0.0015532692,0.0012831832,0.004963182,0.006960927,0.002020467,0.007901955,0.024969427],"category_scores_gemma":[0.029281205,0.0006086276,0.0010066024,0.0006978103,0.003601703,0.005646747,0.003099812,0.025176518,0.025471767],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000042999454,0.0000047770864,0.000023866669,0.0000086896825,0.0000016119292,0.000026918062,0.000025210102,0.0000062220693,0.000012729934,0.0012525143,0.9950937,0.0035394265],"study_design_scores_gemma":[0.000005919763,0.000011519291,0.00007969403,0.00009586953,0.0000018320827,0.00019706883,0.00011659618,0.000023216453,0.00003681062,0.0015976962,0.9978235,0.000010344651],"about_ca_topic_score_codex":0.006392862,"about_ca_topic_score_gemma":0.010485652,"teacher_disagreement_score":0.024969427,"about_ca_system_score_codex":0.0033225573,"about_ca_system_score_gemma":0.0088747265,"threshold_uncertainty_score":0.08353108},"labels":[],"label_agreement":null},{"id":"W2497649390","doi":"10.1172/jci80711","title":"BRPF1 is essential for development of fetal hematopoietic stem cells","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; National Research Council Canada; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Bromodomain; Biology; Stem cell; Epigenetics; Cell biology; Chromatin; Haematopoiesis; Hematopoietic stem cell; Bone marrow; Cancer research; Immunology; Genetics; Gene","score_opus":0.06766940587715499,"score_gpt":0.36472062741531364,"score_spread":0.29705122153815866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2497649390","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96282965,0.010989196,0.015460973,0.0007273917,0.00013755143,0.00008013615,0.0036579142,0.001050458,0.0050668307],"genre_scores_gemma":[0.9882045,0.0020509644,0.0038875933,0.000088550725,0.000018338837,0.00003782382,0.0018963935,0.00006911157,0.003746559],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998209,0.000022909695,0.000015694555,0.00004740688,0.00006004261,0.000033006705],"domain_scores_gemma":[0.9998072,0.000023790159,0.00007057602,0.000015969825,0.000016372627,0.000066239554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014718848,0.00038160663,0.00019370827,0.00035694597,0.00022471076,0.00024480376,0.00029756755,0.00045933304,0.0019488689],"category_scores_gemma":[0.00027549756,0.00019798325,0.00016627152,0.0001427522,0.0002617213,0.00015767258,0.00027447508,0.00047670395,0.0009928689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012082978,0.000009212813,0.0004439464,0.000045258785,0.000002920111,0.00018983215,0.00000975758,0.000064129024,0.9952886,0.00015769429,0.00013822218,0.0035295396],"study_design_scores_gemma":[0.000037506805,0.00017552327,0.020973014,0.000027437087,0.00002059893,0.00229823,0.000033280507,0.0009810623,0.95547837,0.00026552984,0.0196976,0.000011886191],"about_ca_topic_score_codex":0.0005958987,"about_ca_topic_score_gemma":0.000613941,"teacher_disagreement_score":0.0019488689,"about_ca_system_score_codex":0.0003218149,"about_ca_system_score_gemma":0.0003217548,"threshold_uncertainty_score":0.0065196157},"labels":[],"label_agreement":null},{"id":"W2508616096","doi":"10.1172/jci86437","title":"BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":215,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; European Federation of Pharmaceutical Industries and Associations; University of Toronto; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Ontario Ministry of Economic Development and Innovation; Novartis Pharma; Ontario Genomics Institute; Wellcome Trust; Pfizer; Princess Margaret Cancer Foundation; National Institutes of Health; Ontario Genomics","keywords":"Adoptive immunotherapy; Immunotherapy; Bromodomain; Persistence (discontinuity); Adoptive cell transfer; Function (biology); Cancer research; Immunology; Biology; T cell; Computational biology; Immune system; Cell biology; Epigenetics; Genetics","score_opus":0.12780423115335657,"score_gpt":0.3737692853268149,"score_spread":0.24596505417345835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2508616096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992584,0.0011420583,0.0041220174,0.00011458886,0.000054498192,0.00010397755,0.0001700064,0.00019810436,0.001510815],"genre_scores_gemma":[0.9936619,0.0007581504,0.0026061162,0.00005771619,0.000020921048,0.00011289316,0.00030434795,0.000024508405,0.002453446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996463,0.000073718555,0.000029364604,0.00005503843,0.00009576206,0.00009985903],"domain_scores_gemma":[0.9998368,0.00003125825,0.00004198542,0.000024177707,0.000015496045,0.00005022874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047149535,0.00064737664,0.0005404763,0.0006320206,0.00020136115,0.00035484514,0.00044469885,0.00048095395,0.001136039],"category_scores_gemma":[0.00017332139,0.00022833723,0.00032092826,0.00024906863,0.0003265911,0.00037567256,0.00023438888,0.0015152812,0.0003174634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030726552,0.00040248677,0.00007114396,0.000032629872,0.0000069814855,0.000021754451,0.000022773305,0.00013184547,0.9971269,0.00009891376,0.000050106555,0.0017271403],"study_design_scores_gemma":[0.0000857696,0.0024901424,0.0007738524,0.00000465325,0.000025453453,0.00009439859,0.00001295288,0.0013272074,0.99416345,0.00005814835,0.00095988903,0.0000040242917],"about_ca_topic_score_codex":0.00038903306,"about_ca_topic_score_gemma":0.00070834573,"teacher_disagreement_score":0.001136039,"about_ca_system_score_codex":0.00032753497,"about_ca_system_score_gemma":0.00025834292,"threshold_uncertainty_score":0.0038003922},"labels":[],"label_agreement":null},{"id":"W2509793709","doi":"10.1172/jci88546","title":"Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalities","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; U.S. National Library of Medicine; National Institute on Aging; National Institutes of Health; American Heart Association","keywords":"Biology; CD8; Memory T cell; Memory cell; Cytotoxic T cell; Immune system; Phenotype; Immunological memory; T cell; Neuroscience; Immunology; Genetics; Immunity; In vitro; Gene","score_opus":0.038261960291860464,"score_gpt":0.2903780032412614,"score_spread":0.25211604294940093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2509793709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99556786,0.0010189485,0.0025355534,0.000036385365,0.000012661133,0.000012528338,0.00008611065,0.00007355081,0.00065642234],"genre_scores_gemma":[0.99813145,0.00032439595,0.0009005801,0.000021374532,0.000009288761,0.000009379003,0.000082233724,0.000005528501,0.00051585404],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99993706,0.000011648241,0.0000069874345,0.000018017488,0.000009464092,0.000016849137],"domain_scores_gemma":[0.99991536,0.000008253982,0.00002486843,0.000018934554,0.000012489878,0.000020027313],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017460492,0.00021722564,0.0001578525,0.00019510592,0.00010276731,0.0002403125,0.000090408495,0.00014968803,0.00093013525],"category_scores_gemma":[0.00013713124,0.000074784366,0.00012286693,0.000064803826,0.00019334584,0.00022597262,0.00018769146,0.00038142936,0.00015955644],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018930732,0.000029574294,0.0016607248,0.000028044047,0.0000034797665,0.00005057112,0.000031142743,0.000050650426,0.9938479,0.0001805994,0.000027860802,0.0039001822],"study_design_scores_gemma":[0.000027497146,0.0020481828,0.04171199,0.000019189769,0.00004636691,0.0010985268,0.00012748207,0.0011034317,0.9491028,0.0006730521,0.004031836,0.000009657479],"about_ca_topic_score_codex":0.00012194262,"about_ca_topic_score_gemma":0.0001730877,"teacher_disagreement_score":0.00093013525,"about_ca_system_score_codex":0.00008228424,"about_ca_system_score_gemma":0.00011450194,"threshold_uncertainty_score":0.0031116009},"labels":[],"label_agreement":null},{"id":"W2515394053","doi":"10.1172/jci85946","title":"A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Deutsches Krebsforschungszentrum; Deutsche Forschungsgemeinschaft; European Foundation for the Study of Diabetes; Eli Lilly and Company","keywords":"FGF21; Endocrinology; Internal medicine; Biology; Glucose homeostasis; Metabolic syndrome; Impaired glucose tolerance; Homeostasis; Fatty liver; Insulin resistance; Obesity; Medicine; Fibroblast growth factor; Disease","score_opus":0.07441223140621776,"score_gpt":0.3685980144045031,"score_spread":0.29418578299828535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515394053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99553925,0.0018802535,0.0015016674,0.00012856451,0.00001887077,0.000017573582,0.00013559643,0.000056235298,0.0007219706],"genre_scores_gemma":[0.9970799,0.0007131848,0.0012546924,0.00007924034,0.000014047949,0.000023793193,0.00015418498,0.000011117888,0.0006697586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999206,0.000021314034,0.0000067858086,0.000020616899,0.0000149084835,0.000015768694],"domain_scores_gemma":[0.9998754,0.000012402685,0.00004790098,0.000012974347,0.000011411394,0.000039812516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001603636,0.0002935253,0.00023164578,0.00018615599,0.00014508938,0.00024071538,0.00009267079,0.00020336588,0.00080220896],"category_scores_gemma":[0.00015729672,0.00012056626,0.00016303695,0.00010733063,0.0003419617,0.00019053445,0.00029373638,0.00049968006,0.00011680813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012392566,0.000047079215,0.0014911651,0.000051149833,0.000010782075,0.0001522987,0.000023027329,0.000028353474,0.99393636,0.00009426234,0.000044354943,0.0028819514],"study_design_scores_gemma":[0.00015634189,0.0028486615,0.13200426,0.000032169453,0.00007822826,0.0019826503,0.00014079006,0.00077166787,0.85579956,0.00053147954,0.005633249,0.000020926434],"about_ca_topic_score_codex":0.00024132252,"about_ca_topic_score_gemma":0.000519318,"teacher_disagreement_score":0.00080220896,"about_ca_system_score_codex":0.00021071846,"about_ca_system_score_gemma":0.0001365937,"threshold_uncertainty_score":0.0026836991},"labels":[],"label_agreement":null},{"id":"W2532476342","doi":"10.1172/jci87968","title":"Transcription factor ETV1 is essential for rapid conduction in the heart","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; U.S. National Library of Medicine; National Center for Research Resources; National Institute of General Medical Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; School of Medicine, New York University; York University; Vanderbilt University","keywords":"Transcription factor; Electrical conduction system of the heart; Internal medicine; Heart failure; Biology; Regulator; Right bundle branch block; Cardiology; Medicine; Cell biology; Gene; Electrocardiography; Genetics","score_opus":0.13247772127998275,"score_gpt":0.42758823356431525,"score_spread":0.2951105122843325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2532476342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97783697,0.00563195,0.009662419,0.00044240773,0.00012892757,0.000023759167,0.0019023138,0.00025307896,0.00411818],"genre_scores_gemma":[0.9904315,0.0009012039,0.0027121184,0.00009295487,0.000014239385,0.000013479456,0.0017221641,0.00005794532,0.004054416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982953,0.00002170195,0.000014024625,0.000057915924,0.000051604613,0.000025117986],"domain_scores_gemma":[0.9998797,0.000023900177,0.00003574624,0.000010904027,0.000012600467,0.000037059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011688557,0.00029605927,0.00018678274,0.00020500887,0.00023322256,0.0003933635,0.00020544758,0.00027741984,0.0018911724],"category_scores_gemma":[0.00018469298,0.00015878255,0.00020714547,0.00011738082,0.00024902233,0.00018411396,0.00030828486,0.0004881842,0.0007954009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007735442,0.000008816843,0.0004981823,0.000022851034,0.0000021798921,0.00007501453,0.000010548416,0.00010644819,0.9971667,0.0002669681,0.000078438716,0.0016864617],"study_design_scores_gemma":[0.000058042402,0.00019436626,0.037093755,0.000047392987,0.000019978812,0.0012570869,0.00009486089,0.003945591,0.93982595,0.00057867175,0.016865348,0.000019037352],"about_ca_topic_score_codex":0.00070038164,"about_ca_topic_score_gemma":0.0011281531,"teacher_disagreement_score":0.0018911724,"about_ca_system_score_codex":0.00047094404,"about_ca_system_score_gemma":0.00026535348,"threshold_uncertainty_score":0.006326556},"labels":[],"label_agreement":null},{"id":"W2541977924","doi":"10.1172/jci87802","title":"Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; Japan Society for the Promotion of Science; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Ontario Institute for Cancer Research; University Health Network","keywords":"RUNX2; Transcription factor; Biology; Cell biology; Adipogenesis; Coactivator; Tyrosine kinase; Genetics; Signal transduction; Mesenchymal stem cell; Gene","score_opus":0.07040951941508372,"score_gpt":0.335123610860241,"score_spread":0.2647140914451573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2541977924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932986,0.0017493751,0.0029977355,0.00014385302,0.000016897242,0.000009967844,0.00010198586,0.00007962098,0.0016019798],"genre_scores_gemma":[0.9979151,0.000288824,0.0005550942,0.000019152347,0.000005787897,0.000008829429,0.00006598054,0.000009108966,0.0011320583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981683,0.000024026327,0.000011707387,0.000039589904,0.00006765788,0.000040251725],"domain_scores_gemma":[0.9999243,0.00001006622,0.000032811036,0.000005798577,0.000008699242,0.000018393477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020217763,0.00027029563,0.00015117737,0.00021441374,0.00021296125,0.00035465692,0.00017973436,0.00014789923,0.0012830145],"category_scores_gemma":[0.0001772396,0.00013990903,0.00015430525,0.0001193088,0.00029855192,0.00015470582,0.00037637856,0.0004147963,0.00034581998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086139546,0.000006938448,0.000574495,0.000012307406,0.0000036375693,0.000070007845,0.000013288024,0.00006347292,0.99772614,0.00022544112,0.000022789514,0.0011952126],"study_design_scores_gemma":[0.00002950839,0.000120810975,0.009029158,0.000003877686,0.0000235467,0.00043460753,0.00005153412,0.0012134236,0.98569506,0.00018356359,0.0032111022,0.0000039191095],"about_ca_topic_score_codex":0.00034715445,"about_ca_topic_score_gemma":0.0007183764,"teacher_disagreement_score":0.0012830145,"about_ca_system_score_codex":0.00029226815,"about_ca_system_score_gemma":0.00035526347,"threshold_uncertainty_score":0.0042921305},"labels":[],"label_agreement":null},{"id":"W2550907688","doi":"10.1172/jci89031","title":"Early pregnancy vitamin D status and risk of preeclampsia","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Fondation du cancer du sein du Québec; National Heart, Lung, and Blood Institute; Genome Canada","keywords":"Preeclampsia; Medicine; Vitamin D and neurology; Pregnancy; Incidence (geometry); Obstetrics; vitamin D deficiency; Vitamin; Internal medicine; Endocrinology; Biology","score_opus":0.07755594017155584,"score_gpt":0.3953379316662747,"score_spread":0.31778199149471886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2550907688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98858005,0.009844356,0.00033183364,0.00028360522,0.000016337339,0.000015671556,0.00020997786,0.000007774588,0.00071031484],"genre_scores_gemma":[0.9985298,0.001048444,0.00020241998,0.000030437752,0.00000984495,0.0000072586295,0.00005368006,0.0000010113631,0.00011707419],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99944,0.000258213,0.000046784673,0.00009890346,0.00011015636,0.000045814802],"domain_scores_gemma":[0.9975908,0.0011310723,0.00084319984,0.00012270878,0.0001269523,0.00018527925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012242064,0.00013983647,0.00032134034,0.0004835791,0.000119509314,0.00033370766,0.00020414182,0.00030112322,0.00095738424],"category_scores_gemma":[0.003708923,0.00015064495,0.00027510885,0.0004902401,0.00025041873,0.00012414128,0.00024464857,0.0005358446,0.000079964],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005487349,0.00012596256,0.9690289,0.000249904,0.00037816045,0.00019697782,0.00009452776,0.00019464898,0.0040822714,0.00012333988,0.00015781054,0.019880187],"study_design_scores_gemma":[0.00017992957,0.0010569497,0.9942477,0.000087337714,0.0004126986,0.0009516585,0.000044426244,0.00038634153,0.0012198546,0.00040124444,0.0010050645,0.0000067533297],"about_ca_topic_score_codex":0.0006926734,"about_ca_topic_score_gemma":0.00043682483,"teacher_disagreement_score":0.0012242064,"about_ca_system_score_codex":0.00026499244,"about_ca_system_score_gemma":0.00026119157,"threshold_uncertainty_score":0.006474316},"labels":[],"label_agreement":null},{"id":"W2552513321","doi":"10.1172/jci88590","title":"MHC class I–associated peptides derive from selective regions of the human genome","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":207,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Université de Montréal; Canada Research Chairs; Fondation du cancer du sein du Québec; Genome Canada","keywords":"Biology; Repertoire; Proteogenomics; Gene; Immunosurveillance; Major histocompatibility complex; Computational biology; Genome; CD8; Genetics; MHC class I; Human leukocyte antigen; Immune system; Genomics; Antigen","score_opus":0.05978519610139422,"score_gpt":0.3199656285088938,"score_spread":0.2601804324074996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2552513321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850928,0.0015174338,0.010427873,0.000103565486,0.000010471541,0.000018579676,0.0015614235,0.000079986785,0.001187895],"genre_scores_gemma":[0.99320024,0.00054059614,0.004374486,0.00003723733,0.000012902437,0.000016878259,0.0013237162,0.000015955997,0.00047797698],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985087,0.000034549892,0.0000089029745,0.000046170167,0.0000383091,0.000021163154],"domain_scores_gemma":[0.99949646,0.0002676069,0.00016551958,0.000024179784,0.00002146955,0.00002473981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023395284,0.00032217285,0.00023708308,0.0005428036,0.00013372085,0.00039676047,0.00012234211,0.0001729112,0.0016449796],"category_scores_gemma":[0.0008658729,0.00014466196,0.00026211282,0.0005669276,0.00021343854,0.00019621594,0.00018500476,0.0003603866,0.00055648363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000836092,0.00012623926,0.31660023,0.00037882957,0.00028413103,0.000655114,0.00022235884,0.005873314,0.57167786,0.0014831565,0.0008003525,0.101062246],"study_design_scores_gemma":[0.000036740956,0.0005294236,0.79626274,0.00008828057,0.000179627,0.0029790504,0.00032132256,0.026687346,0.15799016,0.0042506643,0.0106369415,0.000037740872],"about_ca_topic_score_codex":0.00044260224,"about_ca_topic_score_gemma":0.00043080468,"teacher_disagreement_score":0.0016449796,"about_ca_system_score_codex":0.00013048343,"about_ca_system_score_gemma":0.00012784387,"threshold_uncertainty_score":0.005502999},"labels":[],"label_agreement":null},{"id":"W2559853954","doi":"10.1172/jci88016","title":"LIM domain–binding 1 maintains the terminally differentiated state of pancreatic β cells","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Skaggs School of Pharmacy and Pharmaceutical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; University of Chicago Medicine; National Institute of Child Health and Human Development; University of California, San Diego; National Institute of General Medical Sciences; School of Medicine, Vanderbilt University; National Institutes of Health; Vanderbilt University; University of Pennsylvania; Children's Hospital of Philadelphia; Vanderbilt University Medical Center; University of Chicago","keywords":"PDX1; Cell biology; Homeobox; FOXA2; Biology; Enhancer; Cellular differentiation; Enteroendocrine cell; Progenitor cell; Transcription factor; PAX4; Cell fate determination; Chromatin; Islet; Stem cell; Endocrinology; Insulin; Genetics; Gene; Endocrine system","score_opus":0.05705633134224672,"score_gpt":0.3392721503811061,"score_spread":0.2822158190388594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2559853954","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963463,0.000831043,0.0015901974,0.00004206638,0.00001045299,0.0000062804042,0.0002463601,0.000056686986,0.000870571],"genre_scores_gemma":[0.9943983,0.00042690718,0.0013382902,0.00004373885,0.0000069050516,0.0000138192,0.00080488465,0.000035643872,0.002931408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990237,0.00000834605,0.0000063902835,0.000030273968,0.000026719945,0.000025919404],"domain_scores_gemma":[0.99987984,0.000011607764,0.000028285483,0.000015184783,0.000009971556,0.00005507765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011256164,0.00019749266,0.00016029389,0.00021159908,0.00019118525,0.00036852199,0.00020046768,0.00015282865,0.0010847026],"category_scores_gemma":[0.00010785059,0.00015420787,0.00013669507,0.00010492149,0.00022547631,0.0001584057,0.00034599245,0.00044343612,0.00044935054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035557725,0.000007162306,0.00023533138,0.000010369918,0.0000013007281,0.000014429135,0.000007508824,0.000020307942,0.99916804,0.000044435586,0.000011691636,0.00044385993],"study_design_scores_gemma":[0.00001982791,0.00011605299,0.016414614,0.0000075879198,0.000013448209,0.00021259517,0.000042023512,0.0011878563,0.97785544,0.00010615267,0.004018694,0.0000057875895],"about_ca_topic_score_codex":0.0004703016,"about_ca_topic_score_gemma":0.0010434446,"teacher_disagreement_score":0.0010847026,"about_ca_system_score_codex":0.0003444676,"about_ca_system_score_gemma":0.00021394812,"threshold_uncertainty_score":0.0036287308},"labels":[],"label_agreement":null},{"id":"W2559992365","doi":"10.1172/jci90837","title":"Prolonged red cell storage before transfusion increases extravascular hemolysis","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Blood transfusion and management","field":"Medicine","cited_by":200,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; Center for Clinical and Translational Research; National Institutes of Health","keywords":"Hemolysis; Medicine; Red Cell; Blood preservation; Blood transfusion; Red blood cell; Red Blood Cell Transfusion; Randomized controlled trial; Surgery; Internal medicine; Physiology","score_opus":0.041213776473162135,"score_gpt":0.3219256773531436,"score_spread":0.28071190087998144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2559992365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984586,0.0011493567,0.0001704902,0.000037373695,0.0000115779185,0.0000108348195,0.000023559473,0.000011138071,0.00012713195],"genre_scores_gemma":[0.9990336,0.00033905785,0.00028653062,0.00008167313,0.000021567403,0.0000157647,0.000060878025,0.0000031571403,0.00015777131],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9997707,0.000095218624,0.000027956896,0.00003931639,0.0000363334,0.00003037472],"domain_scores_gemma":[0.9988607,0.00034145472,0.0005496419,0.00008226556,0.000058025413,0.00010794882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006225808,0.00022319151,0.0003255308,0.00008906699,0.00011805161,0.00029648948,0.000119733566,0.0003173983,0.0024634171],"category_scores_gemma":[0.0012368537,0.00008785785,0.0002927241,0.00008824778,0.00023103566,0.00016776628,0.00017795405,0.00037491033,0.00019239912],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.15724231,0.0038360958,0.100055695,0.0015666726,0.0011567773,0.00080299284,0.000525051,0.001030953,0.60453784,0.00026438938,0.001409662,0.12757154],"study_design_scores_gemma":[0.00466753,0.1810861,0.6533205,0.00043082563,0.0014794131,0.004969334,0.00028389203,0.002246634,0.14604844,0.00039506968,0.0050044656,0.000067858615],"about_ca_topic_score_codex":0.0001854295,"about_ca_topic_score_gemma":0.00015286976,"teacher_disagreement_score":0.0024634171,"about_ca_system_score_codex":0.00015196535,"about_ca_system_score_gemma":0.00016512495,"threshold_uncertainty_score":0.008240998},"labels":[],"label_agreement":null},{"id":"W2560187753","doi":"10.1172/jci88648","title":"Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Prohormone convertase; Endocrinology; Prohormone; Internal medicine; Biology; Proinsulin; Knockout mouse; Hormone; Gene; Medicine; Insulin; Genetics","score_opus":0.0408665860268086,"score_gpt":0.3312495679486059,"score_spread":0.2903829819217973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560187753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979353,0.00030538184,0.00088674424,0.00004676701,0.000021991327,0.000013043939,0.00039538453,0.00005708655,0.00033819515],"genre_scores_gemma":[0.99497104,0.00051350717,0.0012548359,0.000045978624,0.0000071532827,0.000022998687,0.0006353964,0.00003434899,0.0025146538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986696,0.000013775132,0.000024702338,0.000036942296,0.00003796492,0.000019595596],"domain_scores_gemma":[0.99983823,0.00002345424,0.000054197815,0.000014005541,0.000006293832,0.00006373073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008094047,0.00055454596,0.0002317527,0.00039135135,0.00015823996,0.00025133844,0.00021930067,0.00035781236,0.0022562975],"category_scores_gemma":[0.0001409949,0.0002533592,0.0002780511,0.00012611425,0.00037990752,0.00018034705,0.00029899768,0.0006145551,0.00041330466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014687242,0.000031678323,0.0003930285,0.000022832231,0.000008891215,0.00020920178,0.000016720707,0.00004619845,0.9982017,0.000042113857,0.000025492627,0.00085517607],"study_design_scores_gemma":[0.00006604288,0.0005524856,0.025754744,0.0000114080785,0.000054107608,0.0021366724,0.000058610935,0.0010650128,0.96820194,0.00007867394,0.0020086428,0.000011646637],"about_ca_topic_score_codex":0.0006694012,"about_ca_topic_score_gemma":0.0013147992,"teacher_disagreement_score":0.0022562975,"about_ca_system_score_codex":0.00018812163,"about_ca_system_score_gemma":0.00017523656,"threshold_uncertainty_score":0.007548094},"labels":[],"label_agreement":null},{"id":"W2560401565","doi":"10.1172/jci88017","title":"Pancreatic β cell identity requires continual repression of non–β cell programs","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; School of Medicine, Indiana University; National Cancer Institute; Consejo Nacional de Ciencia y Tecnología; National Institutes of Health; Université de Genève; York University; University of Colorado Denver; NYU Langone Medical Center","keywords":"Enteroendocrine cell; Biology; Reprogramming; Cell; Transcription factor; Cell biology; Gene; Psychological repression; Cell type; Phenotype; Islet; Downregulation and upregulation; Endocrine system; Insulin; Endocrinology; Genetics; Gene expression; Hormone","score_opus":0.07521647418405705,"score_gpt":0.3801622942873212,"score_spread":0.3049458201032641,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560401565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994528,0.0011689399,0.0026468905,0.000043039137,0.000011801521,0.000009959595,0.00006261089,0.000042491214,0.0014862742],"genre_scores_gemma":[0.9969717,0.0005696126,0.00093264057,0.000030073004,0.000009908194,0.000011825467,0.00015934932,0.0000126671075,0.001302204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999845,0.000023793033,0.000016428774,0.000039274157,0.00004292273,0.000032492575],"domain_scores_gemma":[0.99985516,0.000019147408,0.000044152854,0.000029506538,0.000014552708,0.000037545014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018802534,0.00020751594,0.00019037392,0.00012183278,0.00010087577,0.0005058711,0.00017496006,0.00012972741,0.0008298066],"category_scores_gemma":[0.00018313994,0.000112155474,0.00011202272,0.000090290545,0.00033470528,0.00027569858,0.0003927802,0.00042570377,0.00024105827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008953357,0.000015036458,0.0014520569,0.000017395947,0.000003506447,0.00011027625,0.000023280527,0.000029994595,0.9965634,0.00014386288,0.000010819607,0.0015407725],"study_design_scores_gemma":[0.00003543163,0.00067365624,0.08148434,0.000016637032,0.000023925932,0.002503476,0.00015222504,0.0008235407,0.9092835,0.00032883653,0.0046634865,0.000010882047],"about_ca_topic_score_codex":0.0001717005,"about_ca_topic_score_gemma":0.0002546568,"teacher_disagreement_score":0.0008298066,"about_ca_system_score_codex":0.00014208812,"about_ca_system_score_gemma":0.0002158537,"threshold_uncertainty_score":0.0027760267},"labels":[],"label_agreement":null},{"id":"W2563063938","doi":"10.1172/jci89354","title":"Astrocytic calcium release mediates peri-infarct depolarizations in a rodent stroke model","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Diego; Deutsches Zentrum für Neurodegenerative Erkrankungen; Deutsche Forschungsgemeinschaft; European Commission; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Glutamate receptor; Calcium; Calcium in biology; Ischemia; Stroke (engine); Neuroscience; Calcium imaging; Medicine; Biology; Pathology; Internal medicine; Endocrinology; Receptor","score_opus":0.20231707546111172,"score_gpt":0.4413152203005916,"score_spread":0.2389981448394799,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2563063938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98282397,0.002406912,0.010376868,0.00039192935,0.00018530725,0.0002597211,0.0007526217,0.00048769184,0.0023149252],"genre_scores_gemma":[0.9823476,0.002799666,0.007435166,0.00018389421,0.00006121865,0.00063684594,0.0009501468,0.00007806811,0.005507386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996389,0.000042410924,0.000051839655,0.000089650195,0.00008982761,0.00008732435],"domain_scores_gemma":[0.99976474,0.00001112706,0.000080545215,0.000050362825,0.000031952288,0.00006131404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044249892,0.0008202669,0.0008926385,0.0009062764,0.00043809693,0.0004455432,0.0006383303,0.00071157847,0.0012941419],"category_scores_gemma":[0.0002151633,0.00043759987,0.0007142962,0.00039774168,0.0005930162,0.0005589336,0.00045941843,0.0016971776,0.00061154773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066826714,0.00033931885,0.00017408509,0.000084058986,0.000020582866,0.00024359325,0.00004672924,0.00009231695,0.9964296,0.00017707526,0.00014797818,0.0015763511],"study_design_scores_gemma":[0.000352317,0.0048616175,0.008564378,0.000050554823,0.00014683873,0.0010840419,0.00013538286,0.0033341327,0.9778651,0.0005593927,0.0030171592,0.000029030944],"about_ca_topic_score_codex":0.0008694179,"about_ca_topic_score_gemma":0.0021355413,"teacher_disagreement_score":0.0012941419,"about_ca_system_score_codex":0.0004238389,"about_ca_system_score_gemma":0.000508789,"threshold_uncertainty_score":0.004329324},"labels":[],"label_agreement":null},{"id":"W2564762943","doi":"10.1172/jci88879","title":"Immunologic impact of the intestine in metabolic disease","year":2017,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Dietary Effects on Health","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Toronto General Hospital; Diabetes Canada; University of Toronto","funders":"Toronto General Hospital Research Institute, University Health Network; Canadian Institutes of Health Research; University of Toronto; J.P. Bickell Foundation; Canadian Diabetes Association","keywords":"Immune system; Inflammation; Insulin resistance; Systemic inflammation; Obesity; Diabetes mellitus; Immunity; Immunology; Carbohydrate metabolism; Disease; Acquired immune system; Biology; Endocrinology; Medicine; Internal medicine","score_opus":0.4269777535452439,"score_gpt":0.579447917175087,"score_spread":0.15247016362984311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2564762943","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007271491,0.9985524,0.00006214098,0.00031122327,0.00026559707,0.0000030125696,0.000010440886,0.0000044112207,0.00071800547],"genre_scores_gemma":[0.00046103637,0.99869674,0.00010427564,0.00014559315,0.00021698883,0.0000034868438,0.000013572826,7.340381e-7,0.00035760025],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998462,0.000029454432,0.000027990036,0.000023990402,0.000055772543,0.000016559194],"domain_scores_gemma":[0.9996743,0.00012722948,0.000046450696,0.000009796147,0.00010450729,0.000037687296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052908546,0.000703565,0.0010235928,0.002248246,0.00032072913,0.0010904502,0.00064565014,0.0010921311,0.0041005854],"category_scores_gemma":[0.0007453198,0.00019497759,0.00037516523,0.0020238583,0.00050927955,0.001294257,0.0008995561,0.0017422455,0.0022278002],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009032496,0.000076285854,0.00028401052,0.020251801,0.00008835164,0.0002738637,0.000094939554,0.00017254883,0.0014233812,0.0045612883,0.032677744,0.94000536],"study_design_scores_gemma":[0.000010890869,0.000073334144,0.00091649155,0.0044876668,0.00008515822,0.0013949355,0.00007986664,0.000039583185,0.00023915192,0.0018525623,0.990807,0.000013469774],"about_ca_topic_score_codex":0.00073902134,"about_ca_topic_score_gemma":0.0013372673,"teacher_disagreement_score":0.0041005854,"about_ca_system_score_codex":0.0004565948,"about_ca_system_score_gemma":0.0011442646,"threshold_uncertainty_score":0.01371783},"labels":[],"label_agreement":null},{"id":"W2569110440","doi":"10.1172/jci91081","title":"Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Daiichi Sankyo Europe; National Institute on Aging; University of California, San Diego; National Cancer Institute; Yale University; National Institutes of Health; University of California, Los Angeles; Kansai Medical University","keywords":"NUMB; Cell biology; Downregulation and upregulation; Endosome; Notch signaling pathway; YAP1; Biology; Signal transduction; Signal transducing adaptor protein; Cell cycle; Cell; Transcription factor","score_opus":0.035913638124435966,"score_gpt":0.3351261989184913,"score_spread":0.29921256079405534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2569110440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99376255,0.0014491668,0.0028545435,0.00013278266,0.00001435306,0.000009127885,0.00011360861,0.000056526023,0.0016073231],"genre_scores_gemma":[0.99558747,0.0006630533,0.0012281862,0.000029270965,0.0000041150834,0.0000133239355,0.00013151129,0.0000119073775,0.0023310015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992204,0.000011770733,0.0000068701634,0.000013940762,0.000023243636,0.000022079157],"domain_scores_gemma":[0.999944,0.000004098643,0.00002214649,0.0000041246676,0.000005209287,0.000020359505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011071154,0.0002678904,0.00012309208,0.0002029856,0.00020695418,0.00033319712,0.00011191723,0.00015494543,0.001373599],"category_scores_gemma":[0.00009204812,0.00012439166,0.00012892607,0.00008964377,0.00020462746,0.00022340892,0.0004167405,0.00034480108,0.00040231782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005150569,0.000008111451,0.0004343663,0.00001878115,0.0000035891208,0.00005531089,0.000009460584,0.000047615125,0.9981641,0.00021507767,0.000029919767,0.0009621869],"study_design_scores_gemma":[0.000029009585,0.000112829934,0.015386305,0.000011749246,0.000014644599,0.00057427393,0.000071081864,0.0024521078,0.97644514,0.00022321672,0.0046751816,0.00000450333],"about_ca_topic_score_codex":0.00032750313,"about_ca_topic_score_gemma":0.0008536063,"teacher_disagreement_score":0.001373599,"about_ca_system_score_codex":0.00033819876,"about_ca_system_score_gemma":0.00023963934,"threshold_uncertainty_score":0.004595101},"labels":[],"label_agreement":null},{"id":"W2583432826","doi":"10.1172/jci89626","title":"Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Calgary Laboratory Services; McGill University; Alberta Health Services","funders":"National Cancer Institute; National Human Genome Research Institute; National Health and Medical Research Council; Agence Nationale de la Recherche; National Center of Competence in Research Chemical Biology; National Center for Advancing Translational Sciences; National Research Foundation of Korea; Medical Research Council; Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften; Yonsei University; Yonsei University College of Medicine; Deutsche Forschungsgemeinschaft; National Research Foundation; National Institute of General Medical Sciences; Ontario Genomics Institute; Australian National University; European Commission; National Institute of Diabetes and Digestive and Kidney Diseases; ASN Foundation for Kidney Research; SystemsX.ch; Institut des maladies génétiques Imagine; Swim Across America; Sociedad Española de Nefrología; National Institutes of Health; Yale University; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Ontario Genomics; Genome Canada; Canadian Institutes of Health Research; National Science Foundation","keywords":"Biology; Ichthyosis; Nephrotic syndrome; Slit diaphragm; Missense mutation; Mutation; Phenotype; Adrenal insufficiency; Endocrinology; Internal medicine; Genetics; Medicine; Gene; Kidney; Podocyte","score_opus":0.07279641078227955,"score_gpt":0.3840905821315097,"score_spread":0.31129417134923015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583432826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975465,0.00052380364,0.0011208053,0.000035057503,0.000007432172,0.000014414254,0.00018793035,0.000056104593,0.00050796976],"genre_scores_gemma":[0.99769235,0.0004449034,0.0010716933,0.000035770645,0.000008413095,0.000009730144,0.0003081231,0.000018379853,0.00041058502],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998528,0.000018625084,0.000020311843,0.000039335264,0.000050847862,0.000018043049],"domain_scores_gemma":[0.99982053,0.0000354776,0.00007379676,0.000010906938,0.000010075971,0.000049195307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105335814,0.00076781644,0.0003178586,0.00051839143,0.00018099461,0.0001679252,0.00018507392,0.00039730608,0.0007481617],"category_scores_gemma":[0.00025993527,0.00021374912,0.0003421918,0.0002532201,0.00039126928,0.00013092051,0.00045334297,0.00038219953,0.00025887968],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032650697,0.00004338671,0.025811063,0.00012117024,0.00012814139,0.013984761,0.00014174303,0.000276673,0.95215356,0.0001484616,0.00017740097,0.0066870153],"study_design_scores_gemma":[0.00014929127,0.0006021944,0.56314903,0.000045519155,0.00026161212,0.15283923,0.00025695463,0.0031104428,0.2737713,0.00048626793,0.0052746674,0.00005349241],"about_ca_topic_score_codex":0.0004187957,"about_ca_topic_score_gemma":0.0009373071,"teacher_disagreement_score":0.00076781644,"about_ca_system_score_codex":0.00015650857,"about_ca_system_score_gemma":0.00013115656,"threshold_uncertainty_score":0.0025028586},"labels":[],"label_agreement":null},{"id":"W2584913109","doi":"10.1172/jci89455","title":"Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":321,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Peter MacCallum Cancer Centre","keywords":"Chimeric antigen receptor; Cancer research; Adenosine; T cell; CD8; Antigen; Adenosine A2A receptor; Immunology; Receptor; Chemistry; Medicine; Adenosine receptor; Biology; Pharmacology; Immune system; Internal medicine","score_opus":0.11478170529418573,"score_gpt":0.4295939475704932,"score_spread":0.31481224227630744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2584913109","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921644,0.0014699142,0.002654593,0.00014893054,0.00007224015,0.000082086546,0.00014997198,0.00017578523,0.0030821494],"genre_scores_gemma":[0.9960777,0.0005923281,0.0017640606,0.00006496799,0.00003502261,0.000046448335,0.0001227478,0.000020225312,0.0012765182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99958414,0.00010374757,0.000029044199,0.00004939812,0.00009955862,0.00013402764],"domain_scores_gemma":[0.9998485,0.000053541913,0.000027890736,0.000014397711,0.000016224642,0.00003950728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003970367,0.00039948203,0.00067598687,0.00037215985,0.00014589344,0.00055455783,0.00022753095,0.0004665189,0.0016431849],"category_scores_gemma":[0.00020800305,0.00013479442,0.00024762237,0.00020085856,0.00025290356,0.00037040265,0.0002507716,0.0010776925,0.00040793384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042167044,0.0005311714,0.0001624055,0.00007232574,0.000018187555,0.000054075073,0.000036924033,0.0005547605,0.9899156,0.00034997353,0.00029409013,0.0075889537],"study_design_scores_gemma":[0.00020873218,0.006333898,0.002387104,0.000010914641,0.000066693116,0.00022922405,0.000030663694,0.003298592,0.9827687,0.00009310337,0.004563765,0.0000086347445],"about_ca_topic_score_codex":0.00038401503,"about_ca_topic_score_gemma":0.0008864263,"teacher_disagreement_score":0.0016431849,"about_ca_system_score_codex":0.00030827985,"about_ca_system_score_gemma":0.00031648696,"threshold_uncertainty_score":0.0054969788},"labels":[],"label_agreement":null},{"id":"W2590455134","doi":"10.1172/jci91211","title":"Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institutes of Health; JPB Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; University of Pennsylvania","keywords":"Rosiglitazone; Endocrinology; Internal medicine; Epigenome; Insulin resistance; Adipose tissue; White adipose tissue; Biology; PRDM16; Adipocyte; Epigenomics; Insulin; Gene expression; Gene; Genetics; Medicine; DNA methylation","score_opus":0.11205087909154357,"score_gpt":0.4098355529084539,"score_spread":0.2977846738169103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2590455134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9571479,0.0026475461,0.029227871,0.00081102375,0.00023666667,0.00020281783,0.0037070217,0.0015965712,0.004422541],"genre_scores_gemma":[0.9506255,0.004214882,0.020283058,0.0005812497,0.00008536845,0.0003918937,0.0032812734,0.00067651324,0.019860411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996669,0.00005128031,0.000048200458,0.00009026604,0.00008601146,0.00005734376],"domain_scores_gemma":[0.99964404,0.000024337536,0.00011080022,0.000054523083,0.000026678441,0.00013957564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035869883,0.0006918012,0.00048712408,0.0011934753,0.00030506784,0.00050259224,0.0005933116,0.00065475056,0.002677963],"category_scores_gemma":[0.00019396683,0.00054974086,0.00058855745,0.00038303935,0.00053792866,0.00031915552,0.00062157994,0.0017943453,0.00087338476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032645915,0.000059328468,0.0001574125,0.000053589407,0.000018449258,0.00007837724,0.000033088163,0.00012725838,0.9962921,0.0003713639,0.00008493242,0.002397654],"study_design_scores_gemma":[0.0002095796,0.0007030968,0.0057880827,0.00006812701,0.00010242908,0.00056214334,0.0001051766,0.0015321834,0.9773481,0.00042633998,0.013134163,0.000020523321],"about_ca_topic_score_codex":0.000751257,"about_ca_topic_score_gemma":0.0015360138,"teacher_disagreement_score":0.002677963,"about_ca_system_score_codex":0.00028288396,"about_ca_system_score_gemma":0.00039013792,"threshold_uncertainty_score":0.008958697},"labels":[],"label_agreement":null},{"id":"W2594862203","doi":"10.1172/jci87442","title":"Laminar flow downregulates Notch activity to promote lymphatic sprouting","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Biomedical Imaging and Bioengineering; National Eye Institute; China Scholarship Council; American Heart Association","keywords":"KLF2; Lymphatic Endothelium; Cell biology; Lymphatic system; ORAI1; Sprouting angiogenesis; Chemistry; Biology; Immunology; Downregulation and upregulation; Cancer research; Angiogenesis; Biochemistry; Neovascularization","score_opus":0.11379292100032853,"score_gpt":0.42155456837871064,"score_spread":0.3077616473783821,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2594862203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913754,0.001901488,0.00398376,0.00016456188,0.000070866336,0.000048999093,0.00057359895,0.00016299746,0.0017183995],"genre_scores_gemma":[0.99298626,0.00124794,0.0018556952,0.00012825817,0.000020086387,0.00006426448,0.00048149095,0.000027260516,0.0031887873],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998234,0.000018929564,0.000022365542,0.000041886433,0.000040215844,0.00005327952],"domain_scores_gemma":[0.9999039,0.000010488404,0.0000338339,0.0000074757636,0.0000095927835,0.00003466695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016004036,0.00040177756,0.00025934263,0.0002988344,0.00014316222,0.00040639137,0.0001867635,0.0002765302,0.0018787965],"category_scores_gemma":[0.00009301731,0.00018410203,0.00040909805,0.0001370127,0.00026031348,0.00028263408,0.00034662583,0.0007863423,0.00036938832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012846616,0.000031330066,0.0001460153,0.00005021852,0.000004239813,0.000032069554,0.000009976707,0.000042593005,0.9985833,0.000117121555,0.00003357442,0.0008211356],"study_design_scores_gemma":[0.000049300277,0.0002722429,0.005030341,0.000010726819,0.000026593678,0.00010651562,0.000029191762,0.0011092684,0.9911708,0.00008276013,0.0021050659,0.0000072504768],"about_ca_topic_score_codex":0.00061111426,"about_ca_topic_score_gemma":0.00075525406,"teacher_disagreement_score":0.0018787965,"about_ca_system_score_codex":0.00038663868,"about_ca_system_score_gemma":0.00033897572,"threshold_uncertainty_score":0.0062851906},"labels":[],"label_agreement":null},{"id":"W2595778438","doi":"10.1172/jci89452","title":"Amino acid–insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Harvard Stem Cell Institute; National Cancer Institute; National Institutes of Health; Fondation pour la Recherche Médicale; National Institute on Aging; Dubai Harvard Foundation for Medical Research; Massachusetts General Hospital","keywords":"mTORC1; RHEB; Biology; Cell biology; PI3K/AKT/mTOR pathway; Progenitor cell; Stem cell; Nutrient sensing; Signal transduction","score_opus":0.07957725908692895,"score_gpt":0.36268789681925756,"score_spread":0.2831106377323286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2595778438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995909,0.001355173,0.0013049241,0.00010429841,0.000020619744,0.000016853437,0.0002371973,0.000054280943,0.0009977707],"genre_scores_gemma":[0.9974718,0.00045062482,0.000807128,0.00006024379,0.000008202626,0.000016981086,0.00025163565,0.000014311434,0.0009190108],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997875,0.000040997198,0.000028664417,0.00004726085,0.000058296224,0.000037197064],"domain_scores_gemma":[0.9998995,0.00001559567,0.000025862637,0.000018331766,0.000010399742,0.000030303576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017614503,0.00020383121,0.00026043042,0.00023196448,0.0001999225,0.0005510799,0.00018334508,0.00024200405,0.0012229483],"category_scores_gemma":[0.00015236509,0.00012459513,0.0001861743,0.00014345274,0.0004064801,0.0002544493,0.00032926444,0.0006074796,0.00028097446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011407554,0.000017176773,0.00027468003,0.000020428211,0.0000034298744,0.000036762962,0.000010852053,0.00006752541,0.99819535,0.00021126028,0.000030037238,0.0010183674],"study_design_scores_gemma":[0.000015890559,0.00022504185,0.007411054,0.000006921999,0.000021618867,0.00022814212,0.00004092466,0.0010044469,0.98793143,0.00018565236,0.002922286,0.0000065195313],"about_ca_topic_score_codex":0.00026191998,"about_ca_topic_score_gemma":0.00045435748,"teacher_disagreement_score":0.0012229483,"about_ca_system_score_codex":0.00025027216,"about_ca_system_score_gemma":0.00024025475,"threshold_uncertainty_score":0.0040911436},"labels":[],"label_agreement":null},{"id":"W2605235307","doi":"10.1172/jci90129","title":"Isolated polycystic liver disease genes define effectors of polycystin-1 function","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Center for Advancing Translational Sciences; Yale University; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; PKD Australia; National Human Genome Research Institute; Mayo Clinic","keywords":"Polycystic liver disease; Biology; Gene; Loss function; Genetics; Polycystic kidney disease; Candidate gene; Autosomal dominant polycystic kidney disease; Cilium; PKD1; Exome sequencing; Mutation; Medicine; Internal medicine; Phenotype; Kidney","score_opus":0.03963397570603641,"score_gpt":0.33049083393593587,"score_spread":0.2908568582298995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605235307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99716705,0.0009851272,0.0007538098,0.00005199636,0.0000049867235,0.000012490223,0.00030132543,0.000016504491,0.0007066684],"genre_scores_gemma":[0.99782217,0.00038671852,0.00095981336,0.000056531888,0.000006552216,0.00000978171,0.00036953742,0.0000074380705,0.00038149804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998846,0.000024358349,0.000015687416,0.000034833472,0.000023709734,0.0000166766],"domain_scores_gemma":[0.9998264,0.0000562251,0.000059048227,0.000010986929,0.000017340226,0.00003019451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015177231,0.0003681114,0.0003106635,0.00055304426,0.00016410767,0.0003873729,0.00019845442,0.00042295703,0.0010555112],"category_scores_gemma":[0.00041530054,0.00008633014,0.00012770595,0.00043107616,0.00030468128,0.0002299281,0.0004436454,0.00028218792,0.00016632496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002109306,0.00012945695,0.401993,0.0002647728,0.00012045904,0.0068894895,0.0004050056,0.00077360135,0.56383127,0.00084843975,0.0005200246,0.022115184],"study_design_scores_gemma":[0.00007808636,0.0003686455,0.8626394,0.000051510004,0.00012903742,0.026939334,0.0003079395,0.002189837,0.10001465,0.0008236501,0.0064409496,0.00001683314],"about_ca_topic_score_codex":0.00027748174,"about_ca_topic_score_gemma":0.00039116596,"teacher_disagreement_score":0.0010555112,"about_ca_system_score_codex":0.00015143173,"about_ca_system_score_gemma":0.0001135106,"threshold_uncertainty_score":0.0035310388},"labels":[],"label_agreement":null},{"id":"W2610213115","doi":"10.1172/jci91038","title":"Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institute on Drug Abuse; National Institutes of Health; National Natural Science Foundation of China; Fourth Military Medical University; University of Ottawa; Canadian Institutes of Health Research; JPB Foundation","keywords":"Glutamatergic; Endocannabinoid system; Neuroscience; GABAergic; Excitatory postsynaptic potential; Lateral hypothalamus; Preoptic area; Arousal; Hypothalamus; Inhibitory postsynaptic potential; Glutamate receptor; Endocrinology; Chemistry; Internal medicine; Medicine; Psychology; Receptor","score_opus":0.1619572609209045,"score_gpt":0.39538990426772497,"score_spread":0.23343264334682046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2610213115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98821324,0.0017199825,0.0049576187,0.0004283993,0.00010894141,0.00012585575,0.0018331544,0.0003628735,0.0022498297],"genre_scores_gemma":[0.97788244,0.0019209147,0.0066626184,0.00044336112,0.000045527253,0.0005103041,0.0018747658,0.00023573873,0.01042429],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994918,0.000046789864,0.00005142656,0.00017114008,0.000097373384,0.00014145576],"domain_scores_gemma":[0.9995851,0.000032895012,0.00014717165,0.00004591813,0.000029614192,0.00015929615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003186663,0.00066004257,0.00053605257,0.0012178795,0.00043135078,0.00070701074,0.0007902947,0.0008668272,0.0022353493],"category_scores_gemma":[0.00019254137,0.00054800505,0.000864322,0.00032137803,0.0009084572,0.00063091924,0.00043175166,0.0027773173,0.0007857438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006768748,0.00021497419,0.00036442175,0.00004213707,0.000015299187,0.00010491013,0.0000682101,0.000106968895,0.9957353,0.00040688785,0.000105964624,0.002158126],"study_design_scores_gemma":[0.0002223801,0.0016741375,0.010509042,0.000050208728,0.00007945693,0.00037379185,0.00016638084,0.0027509097,0.9792311,0.0004162662,0.0044963295,0.000029986777],"about_ca_topic_score_codex":0.0014418076,"about_ca_topic_score_gemma":0.0022933825,"teacher_disagreement_score":0.0022353493,"about_ca_system_score_codex":0.0009904286,"about_ca_system_score_gemma":0.00055196334,"threshold_uncertainty_score":0.0074779987},"labels":[],"label_agreement":null},{"id":"W2610261021","doi":"10.1172/jci90825","title":"Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; McGill University Health Centre; Princess Margaret Cancer Centre; University of Toronto; Pediatric Oncology Group; University Health Network","funders":"National Institute on Aging; Austrian Science Fund; Temple University; Rotary Foundation; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; National Cancer Institute; National Institutes of Health; European Commission; FP7 Research Potential of Convergence Regions; University of Texas MD Anderson Cancer Center; American Society of Hematology","keywords":"Synthetic lethality; PARP1; Biology; Cancer research; Leukemia; DNA repair; Molecular biology; DNA; Poly ADP ribose polymerase; Polymerase; Genetics","score_opus":0.13283052333399334,"score_gpt":0.4257841127992257,"score_spread":0.2929535894652323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2610261021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.982546,0.0012453094,0.013735209,0.00013433484,0.00003031869,0.00006687447,0.00045656622,0.00027910582,0.0015062692],"genre_scores_gemma":[0.99062014,0.0006734661,0.0059032696,0.0000633018,0.000009813107,0.00004513495,0.000601884,0.000027636184,0.0020553458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985194,0.000022895249,0.000015466014,0.000043354914,0.000041966603,0.000024343432],"domain_scores_gemma":[0.99992466,0.000013738181,0.0000241079,0.000014004881,0.0000075087223,0.00001597208],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017097677,0.00025780898,0.00028557103,0.00021658618,0.00011432388,0.00033528206,0.00017500279,0.000191961,0.00067897077],"category_scores_gemma":[0.00009645018,0.00009687252,0.00019047996,0.0001226789,0.00019368573,0.00016512968,0.00016710117,0.00043188792,0.00016792586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005391134,0.00002387492,0.00018340879,0.000012308758,0.0000031094862,0.000021773365,0.000010484932,0.00013912425,0.9967354,0.00020144341,0.000040789375,0.0025744094],"study_design_scores_gemma":[0.000015240394,0.0003289557,0.0018476903,0.0000024254189,0.000013300844,0.00017976324,0.000012257567,0.0017400652,0.9928362,0.00006557503,0.002955773,0.000002715701],"about_ca_topic_score_codex":0.00024705945,"about_ca_topic_score_gemma":0.00044424483,"teacher_disagreement_score":0.00067897077,"about_ca_system_score_codex":0.00020013117,"about_ca_system_score_gemma":0.00016683307,"threshold_uncertainty_score":0.0022713542},"labels":[],"label_agreement":null},{"id":"W2613572458","doi":"10.1172/jci92450","title":"Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":227,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Medical Research Council; NYU Langone Medical Center; Baker Heart and Diabetes Institute; Diabetes Australia; York University; University of Alabama; National Institutes of Health; Diabetes Australia Research Trust; University of Alabama at Birmingham; National Health and Medical Research Council","keywords":"Thrombocytosis; Platelet; Internal medicine; Thrombopoietin; Endocrinology; Medicine; Diabetes mellitus; Platelet activation; CD36; Receptor; Immunology; Biology; Cell biology; Stem cell","score_opus":0.0755240779911421,"score_gpt":0.362002348624719,"score_spread":0.2864782706335769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2613572458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99646735,0.0019988446,0.00075142976,0.00007375915,0.000022765667,0.0000108349195,0.00007491218,0.00003289524,0.00056725],"genre_scores_gemma":[0.99754167,0.0009293711,0.0006822132,0.000057657122,0.000013451266,0.000013613252,0.00009313337,0.000005235948,0.0006637275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994206,0.000014283285,0.0000064931423,0.000011426214,0.00001200534,0.000013716649],"domain_scores_gemma":[0.99991906,0.0000086457185,0.000029864463,0.0000070096403,0.0000073779365,0.000028000619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011095843,0.00027723738,0.00017667134,0.00020635656,0.000093722396,0.00016853235,0.000090582296,0.00017625725,0.00080774096],"category_scores_gemma":[0.00009549465,0.00009072234,0.0002549527,0.000101685284,0.00013029968,0.000094527044,0.00016176514,0.0004771973,0.00013282352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080808526,0.00008934287,0.0021332433,0.00004224265,0.000023534412,0.00025795645,0.000014266666,0.000057993257,0.9928356,0.000084494684,0.00008766389,0.0035655464],"study_design_scores_gemma":[0.0003170022,0.0022208262,0.15259936,0.000027158332,0.00015397048,0.002141814,0.000106599655,0.002447825,0.83456594,0.0003217053,0.005080277,0.000017567862],"about_ca_topic_score_codex":0.0003624052,"about_ca_topic_score_gemma":0.0004199022,"teacher_disagreement_score":0.00080774096,"about_ca_system_score_codex":0.00013355404,"about_ca_system_score_gemma":0.00008542972,"threshold_uncertainty_score":0.002702117},"labels":[],"label_agreement":null},{"id":"W2615896933","doi":"10.1172/jci89935","title":"MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Weill Cornell Medical College; National Institutes of Health; Hospital for Special Surgery","keywords":"Osteoclast; Osteoporosis; Transcription factor; Osteoblast; Endocrinology; Estrogen-related receptor alpha; Internal medicine; Receptor; Nuclear receptor; Bone remodeling; Cell biology; Bone resorption; Chemistry; Cancer research; Estrogen receptor; Biology; Medicine; In vitro; Biochemistry","score_opus":0.04301113085025202,"score_gpt":0.3388063590332908,"score_spread":0.29579522818303877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2615896933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737767,0.013765283,0.0069311173,0.00060581975,0.000087262284,0.000038140475,0.0010328433,0.00023278668,0.003530017],"genre_scores_gemma":[0.9908393,0.0039103813,0.0018930109,0.00013254517,0.000024450863,0.000021319345,0.00048537878,0.00002163435,0.002671933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998584,0.000026634736,0.000010748125,0.000029104913,0.000040608513,0.000034498757],"domain_scores_gemma":[0.99990964,0.0000114671175,0.000039106486,0.000008672731,0.000016419277,0.000014702461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015508378,0.00027238566,0.00020642151,0.00025797836,0.00014469604,0.0003343774,0.00014824234,0.00018211604,0.001463071],"category_scores_gemma":[0.00016047235,0.00016968414,0.00025664258,0.0001587435,0.00024274911,0.00015551945,0.0002003876,0.0005134453,0.0004476989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042640453,0.00004706143,0.0022408618,0.00009237735,0.00001562404,0.00018679093,0.000025775415,0.00009947848,0.9906572,0.00026635433,0.0002121574,0.005729908],"study_design_scores_gemma":[0.0002335648,0.0008208053,0.10986102,0.000070065485,0.00013324147,0.003901103,0.0002717794,0.0023863185,0.8619668,0.0007534471,0.019571705,0.000030168092],"about_ca_topic_score_codex":0.00033493605,"about_ca_topic_score_gemma":0.0008521374,"teacher_disagreement_score":0.001463071,"about_ca_system_score_codex":0.00017209322,"about_ca_system_score_gemma":0.00016441701,"threshold_uncertainty_score":0.004894495},"labels":[],"label_agreement":null},{"id":"W2616644093","doi":"10.1172/jci92373","title":"Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Xenon Pharmaceuticals (Canada)","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Sodium channel; Depolarization; Dorsal root ganglion; Mutation; NAV1; Membrane potential; Neuroscience; Phenotype; Biology; Medicine; Genetics; Endocrinology; Chemistry; Gene; Sensory system; Sodium","score_opus":0.08212353005331292,"score_gpt":0.35531504401893027,"score_spread":0.27319151396561736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2616644093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99828583,0.00019343471,0.0009783881,0.000035802474,0.000008993459,0.000009435218,0.00010605798,0.000045562712,0.00033642855],"genre_scores_gemma":[0.99853694,0.00023503455,0.000859612,0.000038184902,0.000009977157,0.000008710319,0.00010311646,0.000017914392,0.00019044807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998116,0.000036907357,0.000033521184,0.00004599621,0.000044001456,0.000028040497],"domain_scores_gemma":[0.9997429,0.0000693858,0.00012214949,0.000015918225,0.000011354381,0.000038274946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014108514,0.00066549017,0.0003431086,0.00032800584,0.00015770897,0.0002386161,0.00021157022,0.0004959499,0.0009157146],"category_scores_gemma":[0.00042449453,0.00015374465,0.00028700288,0.00018287227,0.0004376232,0.00016140137,0.00027277417,0.00047260523,0.00023902892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092589864,0.000026547055,0.0013414611,0.000020728627,0.000009895116,0.001233433,0.000022425389,0.00011495006,0.9960471,0.00005870179,0.000024575977,0.0010077005],"study_design_scores_gemma":[0.00015675536,0.0012762345,0.21776935,0.000038420338,0.00013194232,0.055363595,0.00012349915,0.0059237974,0.7168603,0.00063020707,0.0016551582,0.00007080505],"about_ca_topic_score_codex":0.00032147026,"about_ca_topic_score_gemma":0.000512422,"teacher_disagreement_score":0.0009157146,"about_ca_system_score_codex":0.00015141512,"about_ca_system_score_gemma":0.00010609155,"threshold_uncertainty_score":0.003063321},"labels":[],"label_agreement":null},{"id":"W2621167148","doi":"10.1172/jci92233","title":"Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; McGill University Health Centre; Domtar (Canada); Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Ontario Institute for Cancer Research","keywords":"Ubiquitin ligase; Energy metabolism; Metabolism; DNA ligase; Ubiquitin; Bone remodeling; Dynamics (music); Chemistry; Computational biology; Biochemistry; Cell biology; Bioinformatics; Biology; Enzyme; Genetics; Physics; Endocrinology","score_opus":0.041032451241122835,"score_gpt":0.33575998367667864,"score_spread":0.29472753243555583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2621167148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99404573,0.0013738914,0.002617392,0.000087232336,0.000016382248,0.000012245189,0.00020549013,0.00010023905,0.0015414892],"genre_scores_gemma":[0.99658656,0.00033184525,0.0012049385,0.000023510904,0.0000037210793,0.0000083993555,0.0001638113,0.000011630975,0.0016656512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998907,0.000018588953,0.000009052122,0.000026517158,0.00003192607,0.000023134106],"domain_scores_gemma":[0.9999391,0.000004958133,0.00002281237,0.0000051619445,0.000007912473,0.000020205243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010581784,0.00039907667,0.00023203481,0.00032002295,0.0001650908,0.0002529214,0.00016875217,0.0003520286,0.00072053756],"category_scores_gemma":[0.00014302142,0.00012720971,0.00012908944,0.000107038315,0.00023630315,0.00011317112,0.00019543343,0.00023586603,0.00024719775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018314025,0.000018313143,0.0021983266,0.000020089128,0.000007363854,0.00068624434,0.000013906602,0.00012941154,0.9937641,0.00015089696,0.00011019188,0.0027180745],"study_design_scores_gemma":[0.00005089459,0.00028424538,0.050393675,0.000019191679,0.00004607714,0.008802926,0.000063895626,0.0032247212,0.93077874,0.00026406447,0.0060570533,0.000014549845],"about_ca_topic_score_codex":0.0011549112,"about_ca_topic_score_gemma":0.0022925045,"teacher_disagreement_score":0.0011549112,"about_ca_system_score_codex":0.00029169078,"about_ca_system_score_gemma":0.0002407427,"threshold_uncertainty_score":0.0024104118},"labels":[],"label_agreement":null},{"id":"W2627062370","doi":"10.1172/jci89934","title":"Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; McMaster University; University of Minnesota","keywords":"Carbohydrate-responsive element-binding protein; Fructose; Transcription factor; Biology; Endocrinology; Chemistry; Internal medicine; Cell biology; Biochemistry; Medicine; Gene","score_opus":0.17285460531602187,"score_gpt":0.4165621666235441,"score_spread":0.24370756130752225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2627062370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98728275,0.0035958816,0.0062419577,0.00031403493,0.00008099894,0.000046180907,0.0004430778,0.00023577533,0.0017593637],"genre_scores_gemma":[0.9940712,0.0015813813,0.0016471222,0.00009466893,0.000020588917,0.000034948793,0.0005027987,0.000020632948,0.0020266606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999915,0.00001391767,0.0000059808367,0.000017527533,0.000016259506,0.00003132327],"domain_scores_gemma":[0.9999341,0.0000056079944,0.000019200945,0.000008522943,0.000011399381,0.00002118515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013456648,0.00025602302,0.00028642503,0.00016696882,0.00013685483,0.0002074107,0.00016868573,0.00019580049,0.0023395903],"category_scores_gemma":[0.00014201835,0.00008499807,0.0002240247,0.00010538575,0.0001820655,0.00019416686,0.00027547788,0.00057641225,0.00035906406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005206574,0.000052009134,0.00034644944,0.000086526496,0.0000094922925,0.000050685492,0.000011182756,0.00008845078,0.9959692,0.00013780242,0.0001213014,0.0026063202],"study_design_scores_gemma":[0.000087663146,0.00072340487,0.021445954,0.000025160958,0.000034937562,0.00034877923,0.00007528528,0.0014171016,0.9685981,0.00016654322,0.007063763,0.000013244827],"about_ca_topic_score_codex":0.00040342502,"about_ca_topic_score_gemma":0.0005575064,"teacher_disagreement_score":0.0023395903,"about_ca_system_score_codex":0.00018405043,"about_ca_system_score_gemma":0.00017305372,"threshold_uncertainty_score":0.0078267455},"labels":[],"label_agreement":null},{"id":"W2726190005","doi":"10.1172/jci64981","title":"Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cambodian History and Society","field":"Social Sciences","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genome Canada","keywords":"Apoptosis; Human immunodeficiency virus (HIV); Immunology; Medicine; Virology; Biology; Cancer research; Genetics","score_opus":0.0483317623115032,"score_gpt":0.3407060067614723,"score_spread":0.29237424444996907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2726190005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99777776,0.001200893,0.00010459212,0.0000558261,0.000015384965,0.000011423555,0.00012249486,0.000013249925,0.0006984255],"genre_scores_gemma":[0.9987394,0.00026051592,0.00006489308,0.00002934818,0.0000067302576,0.000012549111,0.00011215855,0.0000024996175,0.0007718266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987376,0.000015286922,0.000008398362,0.000019526426,0.00001806366,0.0000649741],"domain_scores_gemma":[0.9998754,0.000011653033,0.000054652384,0.000013510486,0.000014939108,0.000029772902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015272842,0.00016184106,0.00020862852,0.0003836568,0.00029858947,0.0005354852,0.00017365422,0.00025399556,0.0019120714],"category_scores_gemma":[0.00020196877,0.00018011454,0.00014638592,0.00021998315,0.00037771856,0.00024460987,0.00032372956,0.0006312425,0.00028714797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024736854,0.0001709628,0.053779993,0.00012730235,0.00004325276,0.0010282631,0.00028751217,0.00013820136,0.92706007,0.00040889837,0.0005333793,0.013948628],"study_design_scores_gemma":[0.00019622213,0.0012007585,0.8525498,0.00007645478,0.00010328274,0.0034878894,0.0014006074,0.0007657289,0.13444245,0.000526056,0.00523011,0.000020718615],"about_ca_topic_score_codex":0.0014317728,"about_ca_topic_score_gemma":0.0017751803,"teacher_disagreement_score":0.0019120714,"about_ca_system_score_codex":0.0004471933,"about_ca_system_score_gemma":0.00031806534,"threshold_uncertainty_score":0.0063964725},"labels":[],"label_agreement":null},{"id":"W2734554345","doi":"10.1172/jci94378","title":"An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Medical Research Council; British Heart Foundation; Cancer Research UK","keywords":"Biology; Genome-wide association study; Enhancer; Quantitative trait locus; Expression quantitative trait loci; Locus (genetics); Phenotype; Genetics; Epigenomics; Single-nucleotide polymorphism; Genotype; Transcriptome; Gene; Transcription factor; Gene expression; DNA methylation","score_opus":0.08072702147503362,"score_gpt":0.3752455949388032,"score_spread":0.2945185734637696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2734554345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887543,0.0006882387,0.008728496,0.00032184823,0.000023790144,0.000012987058,0.00053219876,0.00008110102,0.0008570474],"genre_scores_gemma":[0.99688345,0.00020131125,0.0019800866,0.00008760475,0.0000066283073,0.000012738291,0.00021859069,0.00001875317,0.0005907132],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985063,0.000052658575,0.000009976182,0.00003839621,0.00002694258,0.000021284104],"domain_scores_gemma":[0.99978036,0.00010662292,0.000053867883,0.000018985207,0.000016488864,0.000023713887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029174503,0.00021763342,0.00019715099,0.00023903509,0.00014223682,0.00024957542,0.00020353349,0.00043319995,0.0025565007],"category_scores_gemma":[0.0005890134,0.00014644022,0.00021560071,0.00014490673,0.00021607897,0.00011774807,0.00030017417,0.0004107481,0.00019012124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017775622,0.00010838577,0.058930613,0.00014003187,0.00022593388,0.0013220408,0.00014420522,0.0011932462,0.9159174,0.0019323173,0.00043350176,0.017874744],"study_design_scores_gemma":[0.00034464663,0.00080048025,0.5733969,0.000127592,0.0008144651,0.006823512,0.0003336354,0.022079755,0.37656406,0.005496688,0.013159034,0.00005915786],"about_ca_topic_score_codex":0.0008958631,"about_ca_topic_score_gemma":0.0008788259,"teacher_disagreement_score":0.0025565007,"about_ca_system_score_codex":0.00014848381,"about_ca_system_score_gemma":0.00017206024,"threshold_uncertainty_score":0.008552372},"labels":[],"label_agreement":null},{"id":"W2741007090","doi":"10.1172/jci90890","title":"TNF is required for TLR ligand–mediated but not protease-mediated allergic airway inflammation","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Advancing Translational Sciences; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; School of Medicine, University of North Carolina at Chapel Hill; National Institutes of Health","keywords":"Immunology; Proteases; Sensitization; Medicine; Inflammation; Tumor necrosis factor alpha; Allergic inflammation; Adjuvant; Eosinophilic; Biology; Pathology","score_opus":0.10375183394460337,"score_gpt":0.3872086290871227,"score_spread":0.28345679514251937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2741007090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921261,0.0032492126,0.002543187,0.00025795854,0.0000797683,0.000025737603,0.000447209,0.000097719254,0.0011731518],"genre_scores_gemma":[0.9976394,0.00042932347,0.0008325359,0.000048554557,0.00001736758,0.000014272537,0.0004123219,0.00001537066,0.00059096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994442,0.00016458351,0.00007378017,0.00008130894,0.00011339374,0.00012268868],"domain_scores_gemma":[0.9994822,0.000077335404,0.0001924499,0.00007969872,0.000045728557,0.00012260201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027452584,0.00029702845,0.00031466587,0.00017521415,0.00024120818,0.0005656575,0.00016707888,0.00047346717,0.0017936486],"category_scores_gemma":[0.00044567703,0.00019697775,0.0003457471,0.00012823922,0.00026410914,0.00039233323,0.00023838776,0.00078495237,0.00102249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030612663,0.00003802376,0.0006487831,0.000031867476,0.0000047900858,0.0001468421,0.000010214124,0.000033482775,0.9978472,0.00006339653,0.000035062483,0.0008341316],"study_design_scores_gemma":[0.00010956841,0.00072392647,0.042616047,0.000034990157,0.000038305243,0.0030134234,0.00012309712,0.0014405745,0.94706905,0.00018896784,0.0046305717,0.000011559003],"about_ca_topic_score_codex":0.00020779471,"about_ca_topic_score_gemma":0.00025839635,"teacher_disagreement_score":0.0017936486,"about_ca_system_score_codex":0.00033573978,"about_ca_system_score_gemma":0.00021227785,"threshold_uncertainty_score":0.00600034},"labels":[],"label_agreement":null},{"id":"W2741133420","doi":"10.1172/jci93488","title":"GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biomedical Research Council; National Medical Research Council; National Institute of General Medical Sciences; Medical Research Council; Terry Fox Foundation; National Cancer Centre of Singapore; National Cancer Institute; National Institutes of Health; Cleveland Clinic","keywords":"Haploinsufficiency; Biology; GATA4; Cancer research; Hepatocyte; Hepatoblastoma; Genetics; Molecular biology; Gene; Transcription factor; Phenotype; Internal medicine; Medicine","score_opus":0.07873833877609238,"score_gpt":0.39277062521215145,"score_spread":0.31403228643605907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2741133420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979634,0.00047564507,0.00072281633,0.00006547,0.00001818317,0.000020861946,0.000087941706,0.000061589075,0.00058400456],"genre_scores_gemma":[0.9974694,0.0002119616,0.000693627,0.000021486514,0.0000035238957,0.000019119945,0.0001340338,0.000011019829,0.001435649],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998902,0.000026719874,0.00001295714,0.00001656305,0.000023895005,0.00002961312],"domain_scores_gemma":[0.99992824,0.000013119679,0.00001690068,0.000008457173,0.000004596025,0.000028610684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001639189,0.00022588558,0.00021779243,0.00017802873,0.00012939693,0.0002058101,0.0002035395,0.00021672933,0.0015348968],"category_scores_gemma":[0.000107098866,0.00015414745,0.000128786,0.000108949775,0.0003008942,0.00013126979,0.00016255373,0.000506656,0.00026455926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022542124,0.000059902562,0.00036042623,0.000022411592,0.000003841916,0.000049616752,0.0000093362,0.000077095305,0.9976553,0.00012434574,0.000034512974,0.0013779324],"study_design_scores_gemma":[0.000055786975,0.00090403215,0.0034069242,0.0000030107774,0.00001504961,0.00035809047,0.000025497791,0.0011462065,0.9921044,0.000062624655,0.0019155608,0.000002842034],"about_ca_topic_score_codex":0.0005593299,"about_ca_topic_score_gemma":0.0013500173,"teacher_disagreement_score":0.0015348968,"about_ca_system_score_codex":0.00027649908,"about_ca_system_score_gemma":0.00031238343,"threshold_uncertainty_score":0.0051347613},"labels":[],"label_agreement":null},{"id":"W2742580821","doi":"10.1172/jci87406","title":"Epiregulin and EGFR interactions are involved in pain processing","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; University of Toronto","funders":"National Institute of Dental and Craniofacial Research; National Institute on Aging; Canadian Pain Society; National Health and Medical Research Council; Canadian Institutes of Health Research; University at Buffalo; University of North Carolina at Chapel Hill; National Institutes of Health; Louise and Alan Edwards Foundation; McGill University; Emory University; Medical Research Council; Battelle","keywords":"Epiregulin; Epidermal growth factor receptor; PI3K/AKT/mTOR pathway; Chronic pain; Cancer research; Protein kinase B; Receptor tyrosine kinase; Tyrosine kinase; Receptor; Medicine; Chemistry; Signal transduction; Cell biology; Biology; Neuroscience; Internal medicine; Amphiregulin","score_opus":0.1802133457176293,"score_gpt":0.4424194082111994,"score_spread":0.26220606249357015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2742580821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738052,0.019689549,0.0025792597,0.00022679938,0.00003661683,0.0000228146,0.00021191197,0.00005382418,0.003374052],"genre_scores_gemma":[0.9925995,0.003650601,0.0010186915,0.000100185076,0.000014479448,0.00001270447,0.00017449525,0.00000588405,0.0024234343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985373,0.000029562745,0.000006411569,0.000026188869,0.000031052692,0.00005296198],"domain_scores_gemma":[0.9999567,0.00000500076,0.000018605431,0.0000033076874,0.0000054774573,0.000010892186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012419812,0.00029299268,0.00023828688,0.00019455158,0.00013699233,0.00031213337,0.00013532786,0.00028473884,0.0013919133],"category_scores_gemma":[0.000097342,0.000103622835,0.00022879946,0.00012742472,0.00017651459,0.00023104316,0.00018170808,0.0004954486,0.00029307985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035108897,0.000043029115,0.0013085548,0.00009129311,0.000026706533,0.0003862113,0.000025308831,0.00013837982,0.98751324,0.0004826217,0.00008513495,0.009548427],"study_design_scores_gemma":[0.000043241806,0.0007916113,0.111061856,0.000032615175,0.00015473086,0.0028927594,0.00013588218,0.0012434949,0.8693849,0.00059089385,0.01364675,0.000021251817],"about_ca_topic_score_codex":0.00030827516,"about_ca_topic_score_gemma":0.0005709224,"teacher_disagreement_score":0.0013919133,"about_ca_system_score_codex":0.00024114677,"about_ca_system_score_gemma":0.00013668073,"threshold_uncertainty_score":0.004656434},"labels":[],"label_agreement":null},{"id":"W2748215501","doi":"10.1172/jci94031","title":"Mice expressing KrasG12D in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; University of Toronto; School of Medicine, Indiana University; Riley Children's Foundation","keywords":"Juvenile myelomonocytic leukemia; Progenitor cell; Biology; Myeloid; Haematopoiesis; Cancer research; Immunology; Stem cell; Cell biology","score_opus":0.09245152628540647,"score_gpt":0.39662340188534867,"score_spread":0.3041718755999422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2748215501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96724015,0.0018111656,0.017841127,0.0008214572,0.00015103645,0.00029545877,0.0033607264,0.0012632626,0.0072155646],"genre_scores_gemma":[0.958952,0.0019125976,0.016560638,0.00027220135,0.000024326653,0.0002996546,0.0024327675,0.00017660427,0.019369267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997116,0.000046955192,0.00004130938,0.000050221202,0.00010091581,0.000048899394],"domain_scores_gemma":[0.9997925,0.000021162545,0.000069998394,0.000019264435,0.000013421145,0.00008358861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022469235,0.00064116035,0.0002431649,0.0008347195,0.00028409157,0.00029720206,0.00046800412,0.000605843,0.0030444365],"category_scores_gemma":[0.00011511258,0.00027099825,0.00022987311,0.00024640193,0.0005396035,0.00029343885,0.00037964794,0.00086104835,0.0010336062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003722847,0.00015716278,0.00080080325,0.00008906006,0.000011981329,0.00052559096,0.000058375885,0.00023768222,0.98836285,0.0013114505,0.000408343,0.007664359],"study_design_scores_gemma":[0.00015877833,0.00092094805,0.006327278,0.000049882976,0.000035394125,0.003021706,0.00010533391,0.001737413,0.96044016,0.00032965917,0.026853213,0.000020209667],"about_ca_topic_score_codex":0.00046279762,"about_ca_topic_score_gemma":0.0014733705,"teacher_disagreement_score":0.0030444365,"about_ca_system_score_codex":0.00043927538,"about_ca_system_score_gemma":0.00034003233,"threshold_uncertainty_score":0.010184646},"labels":[],"label_agreement":null},{"id":"W2755692623","doi":"10.1172/jci96839","title":"Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Diabetes insipidus; Endoplasmic-reticulum-associated protein degradation; Endocrinology; Internal medicine; Aquaporin 2; Antidiuretic; Vasopressin; Thirst; Biology; Unfolded protein response; Medicine; Endoplasmic reticulum; Cell biology","score_opus":0.16799900665632947,"score_gpt":0.44560208844482213,"score_spread":0.2776030817884927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2755692623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747431,0.0039877635,0.007658865,0.0031183073,0.0008277457,0.00007475781,0.0028588518,0.0018999797,0.004830618],"genre_scores_gemma":[0.9666794,0.0042031836,0.00593019,0.00075983885,0.00022375958,0.000099099816,0.0019545194,0.0003579392,0.019792033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997328,0.000022731967,0.000031362877,0.00006707843,0.000083270534,0.000062699226],"domain_scores_gemma":[0.99934846,0.00007733685,0.00028385606,0.000033961835,0.00003495632,0.00022140703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023159344,0.0013417834,0.00043791306,0.001280837,0.00046244948,0.0006131332,0.0005927896,0.0011833243,0.0043896204],"category_scores_gemma":[0.0002493718,0.0004607214,0.00035105337,0.00029922323,0.0009380383,0.00038445642,0.00050917664,0.0014952723,0.0012595891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015919312,0.00027852718,0.0022850384,0.00018481031,0.00006736381,0.0028053296,0.00014222319,0.0002272681,0.97664446,0.0012328874,0.0030452104,0.011494997],"study_design_scores_gemma":[0.0008820041,0.0013645526,0.04318591,0.00017208196,0.00036539076,0.012491419,0.0006863803,0.0055065257,0.88076997,0.001690375,0.052737746,0.0001477398],"about_ca_topic_score_codex":0.000523253,"about_ca_topic_score_gemma":0.001286738,"teacher_disagreement_score":0.0043896204,"about_ca_system_score_codex":0.000467023,"about_ca_system_score_gemma":0.0003505557,"threshold_uncertainty_score":0.014684737},"labels":[],"label_agreement":null},{"id":"W2757802282","doi":"10.1172/jci95442","title":"Mutations in the netrin-1 gene cause congenital mirror movements","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Merz Pharmaceuticals; Royal Society; Marsden Fund; Agence Nationale de la Recherche; Fondation Desmarest","keywords":"Netrin; Biology; Axon guidance; Cell biology; Extracellular; Genetics; Mutation; Gene; Neuroscience; Axon","score_opus":0.317214897720388,"score_gpt":0.446799366039676,"score_spread":0.129584468319288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2757802282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638957,0.0005949361,0.001610363,0.00011219814,0.000033363853,0.000027168528,0.00016336663,0.00008173221,0.0009873186],"genre_scores_gemma":[0.9982079,0.000232481,0.0010974585,0.00003806225,0.000019891177,0.00000781809,0.00007270417,0.000014620999,0.00030903355],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99979454,0.000020975702,0.000024915893,0.00007038606,0.000056135388,0.000033065564],"domain_scores_gemma":[0.99967647,0.000092614224,0.00011732885,0.000015379472,0.00001697981,0.00008129302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001312505,0.0011939809,0.0005144167,0.0007096782,0.00027706803,0.00017478532,0.00035169953,0.0009298823,0.0012276904],"category_scores_gemma":[0.00079363043,0.0002308408,0.00032358916,0.00026794866,0.0006745813,0.00022224443,0.00062327425,0.00041926606,0.00021771519],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008955151,0.00010930617,0.046788678,0.0002562561,0.00017652774,0.46035832,0.00058192946,0.0010224972,0.4700564,0.0013170119,0.0007474367,0.017690236],"study_design_scores_gemma":[0.00011462201,0.00056494604,0.18768011,0.00005234123,0.0001980368,0.70961016,0.00018353194,0.0028281738,0.095171824,0.0006885123,0.0028393634,0.00006838155],"about_ca_topic_score_codex":0.0008357482,"about_ca_topic_score_gemma":0.0012445048,"teacher_disagreement_score":0.0012276904,"about_ca_system_score_codex":0.00041841995,"about_ca_system_score_gemma":0.0002623481,"threshold_uncertainty_score":0.0041069984},"labels":[],"label_agreement":null},{"id":"W2762054879","doi":"10.1172/jci96036","title":"mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of Pennsylvania; National Institutes of Health; American Diabetes Association","keywords":"mTORC1; Secretion; Postprandial; Biochemistry; Lipid metabolism; Internal medicine; Very low-density lipoprotein; Chemistry; Endocrinology; Biology; PI3K/AKT/mTOR pathway; Lipoprotein; Signal transduction; Cholesterol; Medicine; Insulin","score_opus":0.05349823584442829,"score_gpt":0.3656280386875698,"score_spread":0.3121298028431415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762054879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92152053,0.038750827,0.011020176,0.0030381663,0.0011268957,0.00034081383,0.0028753963,0.001739531,0.019587724],"genre_scores_gemma":[0.9766947,0.010076281,0.0043694414,0.00046990218,0.00025413718,0.0001918504,0.0014960137,0.00008750325,0.0063601416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997992,0.000032206,0.000019838211,0.00004411452,0.000050272283,0.000054451],"domain_scores_gemma":[0.99991333,0.000010445899,0.000023457835,0.000007653791,0.000018002838,0.000027082328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021282036,0.0005385507,0.00045588095,0.0006204927,0.00021841004,0.00055727846,0.00023674288,0.00039301414,0.0021950733],"category_scores_gemma":[0.00026189926,0.00023568707,0.00040746276,0.0002775021,0.00025518858,0.00024770357,0.00045060372,0.0010092686,0.0010097553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011280613,0.00022138983,0.0006098392,0.00055264804,0.000049959788,0.00014923819,0.000032679207,0.0003986891,0.9746967,0.0010143444,0.0023067282,0.018839728],"study_design_scores_gemma":[0.00029265645,0.0013243781,0.010989621,0.000067683104,0.00011316382,0.0005693972,0.000051591942,0.0037065628,0.9529424,0.00048019987,0.029433874,0.00002853093],"about_ca_topic_score_codex":0.0005412377,"about_ca_topic_score_gemma":0.0010311931,"teacher_disagreement_score":0.0021950733,"about_ca_system_score_codex":0.00048870116,"about_ca_system_score_gemma":0.0005047197,"threshold_uncertainty_score":0.0073432326},"labels":[],"label_agreement":null},{"id":"W2763401475","doi":"10.1172/jci93437","title":"Proprotein convertase furin regulates osteocalcin and bone endocrine function","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut de Readaptation Gingras Lindsay de Montreal; McGill University; Université du Québec; Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association; Canada Research Chairs; Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke; Johns Hopkins University; Université de Montréal","keywords":"Furin; Osteocalcin; Endocrinology; Proprotein convertase; Internal medicine; Chemistry; Proprotein Convertases; Osteoblast; Biology; Biochemistry; Alkaline phosphatase; Lipoprotein; In vitro; Cholesterol; Medicine; LDL receptor; Enzyme","score_opus":0.110902220689382,"score_gpt":0.42365423091733334,"score_spread":0.31275201022795135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763401475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9698583,0.022795575,0.0024526813,0.00040206133,0.000033205226,0.00003719724,0.00015095125,0.000046296198,0.0042237374],"genre_scores_gemma":[0.99395084,0.0031326404,0.0011272182,0.000055329598,0.000010634595,0.000012525573,0.00007571153,0.0000065009644,0.0016286634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989283,0.000022037868,0.000007610246,0.000019090421,0.000031951844,0.0000264951],"domain_scores_gemma":[0.9998944,0.000018794157,0.000036866793,0.000005239635,0.000016141152,0.000028693985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014503016,0.00017673268,0.00013007026,0.0002582215,0.00016458405,0.00037295168,0.00013161359,0.00022173834,0.0005688868],"category_scores_gemma":[0.00022970702,0.00008567985,0.000119430144,0.00013631524,0.00030313144,0.00015659096,0.00015742771,0.00031531425,0.000117168005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006770489,0.000045956218,0.003518792,0.000061396124,0.000009823876,0.0003983342,0.000048733604,0.000069981834,0.9823743,0.0005281023,0.00013481302,0.012132721],"study_design_scores_gemma":[0.00016748463,0.0006620344,0.14561538,0.00004225106,0.00007775274,0.0022338866,0.00036754351,0.0012422204,0.8359053,0.0011728938,0.012496825,0.000016464628],"about_ca_topic_score_codex":0.0010719687,"about_ca_topic_score_gemma":0.000920446,"teacher_disagreement_score":0.0010719687,"about_ca_system_score_codex":0.00044441002,"about_ca_system_score_gemma":0.00030910654,"threshold_uncertainty_score":0.0032244325},"labels":[],"label_agreement":null},{"id":"W2763583412","doi":"10.1172/jci91258","title":"MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Wallonie-Bruxelles International; Jewish General Hospital; Canadian Institutes of Health Research; Narodowe Centrum Badań i Rozwoju; Réseau de cancérologie Rossy; McGill University","keywords":"EIF4E; Cancer research; Melanoma; Receptor tyrosine kinase; Biology; Targeted therapy; Kinase; Translation (biology); Molecular biology; Cancer; Gene; Messenger RNA; Cell biology; Genetics","score_opus":0.11809667177075721,"score_gpt":0.38793992139436,"score_spread":0.2698432496236028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763583412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961606,0.0012738735,0.0004397211,0.000055670018,0.00001626063,0.00004123986,0.00007506989,0.00003941159,0.0018980668],"genre_scores_gemma":[0.99652267,0.0007703585,0.00054857164,0.000026034,0.000005050734,0.000027036811,0.00014534798,0.000007357779,0.0019476895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994254,0.000011044959,0.0000047376375,0.000009184772,0.000013230032,0.00001918778],"domain_scores_gemma":[0.9999683,0.0000057603647,0.0000061309406,0.0000036673819,0.0000032775902,0.000012991586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008595892,0.00024439587,0.00021241228,0.0001708156,0.00009279008,0.00018167654,0.00011896061,0.00012855988,0.0011592618],"category_scores_gemma":[0.000096251446,0.000072175426,0.000099441146,0.00006654224,0.00010459972,0.000101598336,0.00011663672,0.0003479694,0.00016704432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009491,0.0005061345,0.0005845683,0.000067054454,0.0000117212285,0.00007383063,0.000018567169,0.00028211225,0.98481375,0.00019186147,0.00016621812,0.012335201],"study_design_scores_gemma":[0.00028389643,0.0056825764,0.010510682,0.000015638057,0.000047323338,0.00060730707,0.000037206093,0.0029189463,0.9726079,0.00011632933,0.007164017,0.000008149021],"about_ca_topic_score_codex":0.0003300347,"about_ca_topic_score_gemma":0.0014247308,"teacher_disagreement_score":0.0011592618,"about_ca_system_score_codex":0.00014757593,"about_ca_system_score_gemma":0.00019951291,"threshold_uncertainty_score":0.003878057},"labels":[],"label_agreement":null},{"id":"W2765509977","doi":"10.1172/jci96185","title":"siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Arbutus Biopharma (Canada)","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Marburg virus; Virology; Biology; Virus; Disease; Ebola virus; Medicine; Computational biology; Pathology","score_opus":0.13059801837614865,"score_gpt":0.4724590146823972,"score_spread":0.34186099630624855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765509977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99322456,0.0014403648,0.0020396574,0.00012505414,0.000041801217,0.000091006244,0.00033531012,0.00012164203,0.0025805952],"genre_scores_gemma":[0.9896459,0.0011690272,0.002968085,0.00008975003,0.000023533195,0.00012635207,0.0006109384,0.000045661553,0.005320763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999033,0.000015998907,0.000008441395,0.000026947777,0.00002299038,0.000022254795],"domain_scores_gemma":[0.999923,0.000011199346,0.000017859422,0.000012330776,0.000012406338,0.000023187686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014523069,0.00047009077,0.0003913168,0.00024505105,0.0002267751,0.00024582306,0.00020286391,0.00040602346,0.0015929191],"category_scores_gemma":[0.00013010959,0.00013490244,0.00023893981,0.000058384725,0.00024025887,0.00015051199,0.0001632194,0.00040073178,0.0004635531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019398525,0.000077732046,0.00012685821,0.000037604434,0.0000058580595,0.00006935061,0.0000400981,0.00009858428,0.99638855,0.000074076015,0.00008227063,0.0028051166],"study_design_scores_gemma":[0.00011382976,0.004199421,0.004175259,0.00002083395,0.000032324344,0.0006857275,0.000068094,0.0014319697,0.9812816,0.00016157271,0.007819605,0.000009874098],"about_ca_topic_score_codex":0.00092522224,"about_ca_topic_score_gemma":0.0015533809,"teacher_disagreement_score":0.0015929191,"about_ca_system_score_codex":0.00017637141,"about_ca_system_score_gemma":0.0002469372,"threshold_uncertainty_score":0.0053287745},"labels":[],"label_agreement":null},{"id":"W2765988140","doi":"10.1172/jci94417","title":"GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Institute of Environmental Health Sciences; Pennsylvania State University","keywords":"Follicular phase; Thyroid; Endocrinology; Internal medicine; Cell growth; Hormone; Thyroid-stimulating hormone; Chemistry; Biology; Medicine; Biochemistry","score_opus":0.07672950915312715,"score_gpt":0.35942573311713066,"score_spread":0.2826962239640035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765988140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872127,0.0014750451,0.006068109,0.00013751637,0.00004070621,0.000022304353,0.002178299,0.00054679665,0.0023184624],"genre_scores_gemma":[0.9926036,0.00044669857,0.0024267863,0.000081315644,0.0000065712247,0.00002848199,0.0018624552,0.00009416009,0.0024499015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986553,0.000011719608,0.0000142655035,0.000027936652,0.000048148922,0.000032391483],"domain_scores_gemma":[0.99983263,0.000017265696,0.00005581765,0.000016380103,0.000019240311,0.000058672947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010147867,0.00035963338,0.00025299954,0.0003218901,0.0002498802,0.0002248818,0.00024290747,0.00021508288,0.001497004],"category_scores_gemma":[0.00015367284,0.00020614732,0.00050359115,0.0001809727,0.00036235977,0.0001234446,0.0004996124,0.00042905836,0.0007926195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009255563,0.000005045846,0.00069109217,0.000036829573,0.0000052527625,0.0001394779,0.000014855933,0.000049706723,0.99767774,0.000105028004,0.00007859996,0.001103883],"study_design_scores_gemma":[0.000039187053,0.0001086769,0.048233572,0.000019050622,0.000041956457,0.0012447083,0.000097079945,0.0021904213,0.94013476,0.00027589433,0.0075960252,0.000018688883],"about_ca_topic_score_codex":0.002573328,"about_ca_topic_score_gemma":0.004536732,"teacher_disagreement_score":0.002573328,"about_ca_system_score_codex":0.00042188386,"about_ca_system_score_gemma":0.00062917516,"threshold_uncertainty_score":0.0051166415},"labels":[],"label_agreement":null},{"id":"W2766150382","doi":"10.1172/jci90004","title":"Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Diabetes Canada","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of Michigan; University of Miami; U.S. Department of Veterans Affairs","keywords":"mTORC1; Glucagon; Regulator; Biology; Secretion; Endocrinology; Internal medicine; Glucose homeostasis; Signal transduction; Cell biology; Alpha cell; PI3K/AKT/mTOR pathway; Insulin; Insulin resistance; Beta cell; Islet; Biochemistry; Medicine; Gene","score_opus":0.06490688597260487,"score_gpt":0.35369078320298275,"score_spread":0.2887838972303779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766150382","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99624914,0.0011785879,0.0010671676,0.00011306887,0.000046365814,0.0000180154,0.00047604792,0.000120150165,0.00073158933],"genre_scores_gemma":[0.99491996,0.0011267524,0.0014289701,0.000106915555,0.000020193002,0.00004527845,0.0005451994,0.000057035224,0.0017497067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974734,0.000041642605,0.00004761362,0.000056375768,0.000051640003,0.000055329663],"domain_scores_gemma":[0.9997837,0.000031998912,0.00007816103,0.000021454225,0.0000100568805,0.00007471355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002082386,0.0005517277,0.00045562896,0.0005534772,0.00014247735,0.00042390535,0.00029453868,0.00047518505,0.0017806803],"category_scores_gemma":[0.0001819697,0.0002805649,0.0003349897,0.00023743078,0.0005103598,0.00034146282,0.00024016314,0.0009808644,0.0004017119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008278187,0.000075120035,0.00029386487,0.000040233903,0.000012999714,0.000100778285,0.00001239992,0.00007282245,0.99678516,0.000107447995,0.000054339216,0.0016170085],"study_design_scores_gemma":[0.000118472744,0.0017297576,0.013439363,0.000017762635,0.00007397443,0.0010283411,0.00008683421,0.001087933,0.9793463,0.00017220824,0.0028851242,0.000014011537],"about_ca_topic_score_codex":0.00024650016,"about_ca_topic_score_gemma":0.00024153381,"teacher_disagreement_score":0.0017806803,"about_ca_system_score_codex":0.00024977393,"about_ca_system_score_gemma":0.00024114839,"threshold_uncertainty_score":0.0059570074},"labels":[],"label_agreement":null},{"id":"W2766320271","doi":"10.1172/jci95545","title":"Angiopoietin-1 is required for Schlemm’s canal development in mice and humans","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":199,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Eye Institute; Universidade de São Paulo; National Heart, Lung, and Blood Institute; Ophthalmic Research Institute of Australia; Mallinckrodt Pharmaceuticals; Research to Prevent Blindness; National Institutes of Health; March of Dimes Foundation; University of Wisconsin-Madison; Japan Society for the Promotion of Science; Howard Hughes Medical Institute","keywords":"Schlemm's canal; Angiopoietin; Anatomy; Medicine; Biology; Ophthalmology; Internal medicine; Glaucoma; VEGF receptors","score_opus":0.14848631863683615,"score_gpt":0.4199408368719219,"score_spread":0.27145451823508576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766320271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97402453,0.0052064415,0.009706324,0.00089566875,0.00015265631,0.00013426623,0.003799239,0.00066345546,0.0054173707],"genre_scores_gemma":[0.98981255,0.001697876,0.004072739,0.0002479079,0.00003316601,0.0001390392,0.0010699694,0.0001266511,0.0028001457],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952495,0.000102632584,0.00004714514,0.00013854018,0.00012779434,0.000058801237],"domain_scores_gemma":[0.99955386,0.00009784759,0.00017230365,0.000045333905,0.000020083502,0.00011053967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026250974,0.00046263885,0.00044238838,0.0010445043,0.00040373238,0.00055423606,0.00031549134,0.0008977075,0.0040662196],"category_scores_gemma":[0.00040946205,0.00042365794,0.00035265673,0.00033865788,0.00066853414,0.00027710554,0.0003844278,0.0009383341,0.00084567926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007984286,0.00010063739,0.0029962684,0.00012562986,0.00004683011,0.0026933134,0.00011512656,0.0002836926,0.98371613,0.0013740862,0.00077509927,0.0069747726],"study_design_scores_gemma":[0.00080326357,0.00096961536,0.10579644,0.00020610978,0.00032269282,0.031984393,0.00037482564,0.006952422,0.7934497,0.0024813479,0.056568094,0.00009118302],"about_ca_topic_score_codex":0.0011726258,"about_ca_topic_score_gemma":0.0012066282,"teacher_disagreement_score":0.0040662196,"about_ca_system_score_codex":0.00040739813,"about_ca_system_score_gemma":0.00042919107,"threshold_uncertainty_score":0.013602912},"labels":[],"label_agreement":null},{"id":"W2767047321","doi":"10.1172/jci77398","title":"Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"National Eye Institute; Natural Sciences and Engineering Research Council of Canada; Glaucoma Research Foundation; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; Glaucoma Research Society of Canada","keywords":"Neuroprotection; Astrocyte; Lipoxin; Lipid signaling; Neuroscience; Inflammation; Neurotrophic factors; Signal transduction; Pharmacology; Biology; Medicine; Cell biology; Immunology; Central nervous system; Receptor; Biochemistry","score_opus":0.042253493425841296,"score_gpt":0.36120923729508303,"score_spread":0.31895574386924175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767047321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99282724,0.0034039968,0.0021081353,0.00012696779,0.00003276295,0.00004504094,0.00012992868,0.0000624325,0.0012634702],"genre_scores_gemma":[0.99309397,0.0017513047,0.0026704718,0.00006936073,0.000020633139,0.00005066976,0.00021225658,0.000013251532,0.0021181707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988794,0.000026752246,0.000014420679,0.00001850079,0.000023081879,0.000029186383],"domain_scores_gemma":[0.9999131,0.000007600391,0.000020335918,0.000008367258,0.000013758384,0.0000368092],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018163635,0.00034315995,0.00024924322,0.00041814885,0.00020900303,0.00031604376,0.00010520291,0.00028742102,0.0016871257],"category_scores_gemma":[0.000116200994,0.00010289488,0.00028394294,0.00017433891,0.00034418367,0.00026444628,0.00033673202,0.00050194614,0.00040658415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006063581,0.00008144412,0.0003175635,0.000062681414,0.000011181978,0.00007350134,0.000017568567,0.0000295678,0.99574125,0.000095115174,0.000036072983,0.0029277499],"study_design_scores_gemma":[0.00010974205,0.0023980294,0.007760836,0.000018742396,0.0000416063,0.00030989686,0.00010609879,0.00060700875,0.98616946,0.00021597161,0.0022557564,0.0000069692683],"about_ca_topic_score_codex":0.0005589286,"about_ca_topic_score_gemma":0.0008856416,"teacher_disagreement_score":0.0016871257,"about_ca_system_score_codex":0.00019975884,"about_ca_system_score_gemma":0.00043822415,"threshold_uncertainty_score":0.0056440234},"labels":[],"label_agreement":null},{"id":"W2771211195","doi":"10.1172/jci95946","title":"Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada; Banting and Best Diabetes Centre, University of Toronto; Heart and Stroke Foundation of Canada; Diabetes Canada; AstraZeneca","keywords":"Podocyte; Histone; EZH2; Biology; Cancer research; Nephropathy; Cell biology; Glomerulonephritis; Endocrinology; Internal medicine; Kidney; Diabetes mellitus; Medicine; Biochemistry; Proteinuria","score_opus":0.07856003678865847,"score_gpt":0.4185935177595822,"score_spread":0.34003348097092373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2771211195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936347,0.0023865884,0.0021837123,0.000074048534,0.000016510632,0.000017622455,0.00043037342,0.00010282964,0.0011536623],"genre_scores_gemma":[0.9968714,0.0006673852,0.0006830606,0.000045092107,0.0000023787659,0.00001347565,0.00026401324,0.000011334614,0.0014418367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990153,0.000011666437,0.000008218295,0.000032562195,0.000021075,0.00002490832],"domain_scores_gemma":[0.9999583,0.0000032695996,0.000013197792,0.000006685184,0.000003510342,0.000015057724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015094418,0.00024623988,0.00017669493,0.0002585117,0.00012283775,0.00019109556,0.00010269266,0.00022401469,0.0016087512],"category_scores_gemma":[0.000065185806,0.00011117045,0.00022147657,0.00014599407,0.00021474846,0.000092220675,0.0001781989,0.00031368434,0.00017647906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028729715,0.000029805266,0.0013577449,0.00002929503,0.000013222261,0.0000845366,0.000020902538,0.000074737734,0.99536127,0.00012436188,0.000058410387,0.0025585878],"study_design_scores_gemma":[0.000056494177,0.0005180256,0.069008246,0.000010605976,0.000055573357,0.0011987092,0.00007023925,0.0008826884,0.9224856,0.00021808289,0.005484436,0.000011278327],"about_ca_topic_score_codex":0.0009965631,"about_ca_topic_score_gemma":0.0018805178,"teacher_disagreement_score":0.0016087512,"about_ca_system_score_codex":0.00026230584,"about_ca_system_score_gemma":0.0001677994,"threshold_uncertainty_score":0.0053818226},"labels":[],"label_agreement":null},{"id":"W2772059359","doi":"10.1172/jci97233","title":"Discovery, characterization, and clinical development of the glucagon-like peptides","year":2017,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":399,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canada Research Chairs","keywords":"Glucagon-like peptide-2; Translational science; Short bowel syndrome; Relevance (law); Computational biology; Medicine; Data science; Bioinformatics; Biology; Computer science; Internal medicine; Political science; Pathology; Biochemistry; Peptide","score_opus":0.2527332337757946,"score_gpt":0.4628754719202606,"score_spread":0.21014223814446598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2772059359","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024302056,0.99797875,0.00025513113,0.00042405495,0.0001864576,0.0000069300463,0.00002114941,0.00000610607,0.00087842136],"genre_scores_gemma":[0.0011491707,0.9976255,0.00032855442,0.0002604456,0.0001564592,0.0000086428845,0.00003978947,0.0000018928496,0.000429461],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997211,0.000053602525,0.00004457983,0.00004291749,0.00011031236,0.00002736872],"domain_scores_gemma":[0.99949026,0.00023463761,0.00007321693,0.000019121246,0.0001284649,0.00005426132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011702313,0.0006411493,0.00085236406,0.0024340614,0.00018511858,0.0010811918,0.00058386,0.00091784244,0.0020009351],"category_scores_gemma":[0.0015595447,0.00023629909,0.0004568445,0.0014051868,0.0006266512,0.001294378,0.00072382455,0.0019759743,0.0014083768],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011214598,0.00007011393,0.00034285328,0.009708194,0.00005792175,0.0003479011,0.000054991822,0.00025309535,0.0037974783,0.005170218,0.015294369,0.9647907],"study_design_scores_gemma":[0.000027550352,0.0001743469,0.0009921064,0.0029081563,0.00009141543,0.002180401,0.000051289044,0.00007810218,0.0024031415,0.0022255057,0.98884493,0.000023015447],"about_ca_topic_score_codex":0.00047138912,"about_ca_topic_score_gemma":0.00060672185,"teacher_disagreement_score":0.0024340614,"about_ca_system_score_codex":0.0004926038,"about_ca_system_score_gemma":0.0013398349,"threshold_uncertainty_score":0.0066937804},"labels":[],"label_agreement":null},{"id":"W2784540562","doi":"10.1172/jci97555","title":"Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":191,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Maple Leaf Medical Clinic","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; National Institute on Aging; Center for AIDS Research, University of Washington; University of Toronto; George Washington University; National Cancer Institute; National Institutes of Health; National Institute of Mental Health; amfAR, The Foundation for AIDS Research","keywords":"Cytotoxic T cell; CD8; Immunology; Biology; Immune system; Latency (audio); Virus latency; Virology; Virus; Effector; Viral replication; In vitro; Genetics; Computer science","score_opus":0.07475016359552437,"score_gpt":0.3684097136453358,"score_spread":0.2936595500498114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2784540562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98869437,0.005021518,0.0036745886,0.00030359332,0.000042240517,0.00006872995,0.00009873797,0.00013704044,0.00195923],"genre_scores_gemma":[0.9956886,0.00087313115,0.0017780765,0.00014848735,0.000034893135,0.000037584323,0.000113744485,0.000014815178,0.0013106632],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9997551,0.000061588406,0.000021365247,0.000040964875,0.00004286238,0.000078157966],"domain_scores_gemma":[0.9998104,0.00006850963,0.000030513902,0.000050425297,0.000015930933,0.000024182327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025451093,0.00024617324,0.00035912672,0.00012845681,0.00011439008,0.00058418844,0.0002599063,0.00044299394,0.00195752],"category_scores_gemma":[0.00030412318,0.00016515581,0.0002165298,0.000084866784,0.00021852524,0.00038300268,0.00027858076,0.0010015859,0.00054233096],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002604123,0.00011981884,0.0011734014,0.000106299085,0.000015309748,0.00011642405,0.0000696628,0.00015122344,0.9809988,0.00023693789,0.00015164285,0.016600074],"study_design_scores_gemma":[0.00022371598,0.0052583287,0.014689692,0.000037674312,0.000081992315,0.0020999652,0.00014217228,0.0027874953,0.963285,0.00082748913,0.0105480915,0.000018362376],"about_ca_topic_score_codex":0.0001204533,"about_ca_topic_score_gemma":0.00022213152,"teacher_disagreement_score":0.00195752,"about_ca_system_score_codex":0.00010056726,"about_ca_system_score_gemma":0.00010921014,"threshold_uncertainty_score":0.006548524},"labels":[],"label_agreement":null},{"id":"W2784831101","doi":"10.1172/jci94840","title":"COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"York University; U.S. Department of Defense; University of Minnesota; Geoffrey Beene Cancer Research Center; Gerstner Family Foundation; Memorial Sloan-Kettering Cancer Center; National Cancer Institute; Office of Defense Programs; Cancer Research UK; GIST Cancer Research Fund; Prostate Cancer Foundation","keywords":"Transcriptome; MAPK/ERK pathway; Sensitivity (control systems); Cell biology; Biology; Genetics; Signal transduction; Gene; Gene expression; Engineering","score_opus":0.04126453199566905,"score_gpt":0.3278556770233905,"score_spread":0.2865911450277215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2784831101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976762,0.00066664617,0.0005290884,0.000043893073,0.0000059910585,0.000008918627,0.0003346071,0.000039196813,0.00069548056],"genre_scores_gemma":[0.997999,0.00025872493,0.00032626832,0.000022170212,0.0000020391526,0.000011669407,0.00042502087,0.000010648285,0.0009443994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991333,0.000008856352,0.0000061778624,0.000023214545,0.000018871204,0.000029545312],"domain_scores_gemma":[0.99993503,0.0000070643264,0.000021321232,0.0000058617848,0.000009615256,0.000021045178],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006794561,0.00020581853,0.00019673187,0.00020374784,0.00014206862,0.00027106647,0.000108979286,0.00016666025,0.0011016001],"category_scores_gemma":[0.00008982278,0.00011045751,0.00017029389,0.00010427277,0.00013210217,0.00013510893,0.00015226602,0.00034379438,0.00027191598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012882604,0.00001868462,0.00049595913,0.000010213362,0.0000028229283,0.000023055667,0.0000050457593,0.0000405795,0.99845624,0.000021334356,0.000030622105,0.00076652574],"study_design_scores_gemma":[0.000011148116,0.00014638888,0.039462935,0.0000029577564,0.000011040114,0.00020655974,0.00003649252,0.0011215421,0.9579666,0.00004956904,0.0009798383,0.0000048393927],"about_ca_topic_score_codex":0.00041698094,"about_ca_topic_score_gemma":0.00069115317,"teacher_disagreement_score":0.0011016001,"about_ca_system_score_codex":0.00028786063,"about_ca_system_score_gemma":0.00013196583,"threshold_uncertainty_score":0.003685236},"labels":[],"label_agreement":null},{"id":"W2785195392","doi":"10.1172/jci97650","title":"iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Institute of General Medical Sciences; Weill Cornell Medical College; Hospital for Special Surgery; Lupus Research Alliance; National Institutes of Health; Lupus Research Institute; Universiteit van Amsterdam; Amgen","keywords":"Lupus nephritis; Kidney; Cancer research; Tumor necrosis factor alpha; Pathogenesis; Signal transduction; Kidney disease; Biology; Immunology; Internal medicine; Endocrinology; Medicine; Cell biology; Disease","score_opus":0.11955520764629732,"score_gpt":0.40362877501758393,"score_spread":0.28407356737128664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785195392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922002,0.0034716728,0.0012722604,0.00020827702,0.00003958452,0.000030433168,0.00036791508,0.00014687305,0.0022627553],"genre_scores_gemma":[0.9951826,0.001035514,0.0007661661,0.00010100968,0.000023830386,0.00003750952,0.0003999234,0.00001332844,0.0024401161],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980634,0.000039775947,0.000017430186,0.000034601904,0.00005130624,0.000050661623],"domain_scores_gemma":[0.999899,0.0000058157816,0.000034521814,0.000009081752,0.000008168976,0.000043233464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019614393,0.00030135672,0.00029600225,0.00023379631,0.0001534033,0.00037420992,0.00013930268,0.0002938179,0.0014874133],"category_scores_gemma":[0.00008852651,0.00012632115,0.0002003406,0.0001404232,0.00023541196,0.0001581793,0.00022457456,0.0008673634,0.00037995915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071087066,0.00013552584,0.0014594349,0.00010724597,0.000013280665,0.00019276807,0.00002153959,0.000052608666,0.99421,0.00008904393,0.00016853632,0.0028390808],"study_design_scores_gemma":[0.0002304155,0.0020918888,0.05385818,0.000042930544,0.00009458434,0.002797423,0.00014407598,0.0013334074,0.9273256,0.0001838447,0.011884394,0.000013254186],"about_ca_topic_score_codex":0.00015050253,"about_ca_topic_score_gemma":0.0004060982,"teacher_disagreement_score":0.0014874133,"about_ca_system_score_codex":0.00016833225,"about_ca_system_score_gemma":0.00017512213,"threshold_uncertainty_score":0.0049758554},"labels":[],"label_agreement":null},{"id":"W2786220274","doi":"10.1172/jci94956","title":"Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Inselspital, Universitätsspital Bern; Université de Lausanne; University of Bern; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"GATA1; Erythropoiesis; Biology; Messenger RNA; Translation (biology); Molecular biology; Polysome; Gene knockdown; Cell biology; Protein biosynthesis; Ribosome; Gene; RNA; Stem cell; Haematopoiesis; Genetics; Internal medicine; Anemia; Medicine","score_opus":0.050911035982981204,"score_gpt":0.3522489635023838,"score_spread":0.30133792751940264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2786220274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979323,0.011336112,0.004952777,0.00027528935,0.00005096422,0.000029998113,0.00035029417,0.00021816322,0.0034632508],"genre_scores_gemma":[0.9917991,0.0030513422,0.0022924298,0.00006239605,0.000016590278,0.000014555251,0.00022718443,0.000025636,0.0025107523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991155,0.000018445715,0.0000066204498,0.000026333013,0.000018325816,0.000018648041],"domain_scores_gemma":[0.9999311,0.000011928652,0.000030436635,0.000004638446,0.0000066067605,0.000015360578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015313645,0.00026264068,0.00016198217,0.00018133508,0.00011405853,0.00025672725,0.00013436594,0.00014434449,0.0007677791],"category_scores_gemma":[0.0001302906,0.00012026048,0.00011347943,0.00007272197,0.0002201737,0.000100324076,0.00012038349,0.00027894592,0.00029727293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000760142,0.000012379864,0.0008200805,0.000029799914,0.0000032628839,0.000050877872,0.0000103140255,0.000049059832,0.99492246,0.0001683667,0.000076176395,0.0037811587],"study_design_scores_gemma":[0.000013030672,0.0001903304,0.015457352,0.000007791261,0.000014664309,0.00043423873,0.000019628085,0.0008615287,0.9787435,0.00012677723,0.0041268617,0.0000043071436],"about_ca_topic_score_codex":0.00020390391,"about_ca_topic_score_gemma":0.00037936502,"teacher_disagreement_score":0.0007677791,"about_ca_system_score_codex":0.00027495754,"about_ca_system_score_gemma":0.00016653571,"threshold_uncertainty_score":0.0025684237},"labels":[],"label_agreement":null},{"id":"W2788105677","doi":"10.1172/jci98463","title":"Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"National Center for Advancing Translational Sciences; National Center for Research Resources; National Cancer Institute; University of California, Los Angeles; National Institutes of Health; Michael Smith Health Research BC; National Institute of Allergy and Infectious Diseases; University of Pittsburgh; Johns Hopkins Bloomberg School of Public Health; Wellcome Trust; Northwestern University","keywords":"Allotype; CD8; HLA-B Antigens; Antibody; Biology; Immunology; Receptor; HLA-B; Immunoglobulin domain; B cell; Human leukocyte antigen; Immune system; Genetics; Antigen","score_opus":0.050959640177995806,"score_gpt":0.30466449684222924,"score_spread":0.2537048566642334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788105677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99952877,0.000069167996,0.000107089865,0.000019030944,0.000004042647,0.0000011034793,0.000048318325,0.0000044324865,0.00021810069],"genre_scores_gemma":[0.9997453,0.000029058108,0.000046608242,0.000019417907,0.0000028058096,9.3197144e-7,0.000038161757,0.00000419559,0.00011342952],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99973017,0.0000861333,0.000021242346,0.00007512228,0.000031697127,0.000055675515],"domain_scores_gemma":[0.9997011,0.00010286156,0.000080091624,0.000053765078,0.000019259734,0.000042848496],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030907858,0.00022159232,0.0002306527,0.00020901319,0.00018492893,0.0003863373,0.00019864828,0.0003643373,0.0019784367],"category_scores_gemma":[0.00091145886,0.00013066771,0.00020681688,0.00022997898,0.00029068417,0.00012619786,0.00021207516,0.00039784238,0.00022998666],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047946204,0.00028609953,0.7309467,0.00006335977,0.00051370304,0.0010502143,0.000423268,0.00092337583,0.23613608,0.00064097985,0.00061091717,0.023610633],"study_design_scores_gemma":[0.00008998041,0.0006291931,0.97663337,0.000024130915,0.00033835092,0.0014557156,0.00023778186,0.001518563,0.017450316,0.0005794771,0.0010285091,0.0000146303355],"about_ca_topic_score_codex":0.0013153615,"about_ca_topic_score_gemma":0.0009816468,"teacher_disagreement_score":0.0019784367,"about_ca_system_score_codex":0.00012310676,"about_ca_system_score_gemma":0.00012907197,"threshold_uncertainty_score":0.0066184998},"labels":[],"label_agreement":null},{"id":"W2788525877","doi":"10.1172/jci95873","title":"Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":260,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Cancer Institute; Yale University; National Institutes of Health; Cancer Prevention and Research Institute of Texas; Susan G. Komen for the Cure","keywords":"XBP1; Biology; Unfolded protein response; Cancer research; Gene silencing; Transcription factor; Downregulation and upregulation; Cell biology; Endoplasmic reticulum; Genetics; Gene; RNA; RNA splicing","score_opus":0.03718933592934251,"score_gpt":0.3676113315034202,"score_spread":0.3304219955740777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788525877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995823,0.0011868447,0.0013041567,0.0001450007,0.000037949158,0.000044378103,0.00023672238,0.00014242293,0.0010794678],"genre_scores_gemma":[0.99521327,0.0012353358,0.0015011177,0.000047604797,0.0000133860985,0.000045445093,0.0004072406,0.000017878787,0.0015187428],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999199,0.000016193371,0.000007754592,0.000011900182,0.00001934702,0.000024922034],"domain_scores_gemma":[0.9999473,0.000007463123,0.000016714459,0.0000069943267,0.000004572186,0.000016969934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013780106,0.00031653617,0.00035912928,0.00020596715,0.00013248605,0.00021971633,0.00023833664,0.00019476893,0.00083132304],"category_scores_gemma":[0.000076987286,0.00014849457,0.00014993774,0.00017103563,0.00023258413,0.00014219424,0.00014352678,0.00082426885,0.00025390668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039819122,0.00026339057,0.00013477908,0.000060181927,0.0000085376,0.000036969002,0.000015058961,0.00019367086,0.9939903,0.00016100636,0.0001406326,0.0045974613],"study_design_scores_gemma":[0.000118159325,0.0019574284,0.0022927683,0.0000070295387,0.000023792965,0.00027126426,0.000028272958,0.0019100345,0.9904779,0.00006953778,0.0028384253,0.000005213727],"about_ca_topic_score_codex":0.0002678258,"about_ca_topic_score_gemma":0.00067487516,"teacher_disagreement_score":0.00083132304,"about_ca_system_score_codex":0.00020598974,"about_ca_system_score_gemma":0.00024106701,"threshold_uncertainty_score":0.0027810931},"labels":[],"label_agreement":null},{"id":"W2788648365","doi":"10.1172/jci98589","title":"Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Vascular Malformations Diagnosis and Treatment","field":"Medicine","cited_by":286,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Human Genome Research Institute; National Institutes of Health; Brain Tumour Charity; National Institute for Health and Care Research; Melanoma Research Alliance; Wellcome Trust; Medical Research Council; Wellcome","keywords":"Zebrafish; Neuroblastoma RAS viral oncogene homolog; KRAS; Medicine; Cancer research; Trametinib; Pathogenesis; Targeted therapy; Biology; Cancer; Bioinformatics; Mutation; Genetics; MAPK/ERK pathway; Pathology; Gene; Signal transduction","score_opus":0.09992566510296441,"score_gpt":0.3928731058384804,"score_spread":0.292947440735516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788648365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984281,0.0002216656,0.00052860775,0.000030309206,0.0000043426967,0.000011825768,0.00006918428,0.000032502117,0.00067358],"genre_scores_gemma":[0.99927574,0.00006773841,0.00047406592,0.000012824082,0.0000052105192,0.0000033450713,0.000051346105,0.0000072538687,0.000102497455],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998318,0.000019988393,0.000016300428,0.000045410172,0.00005098319,0.000035424888],"domain_scores_gemma":[0.9995828,0.00011762202,0.00017869554,0.000019808664,0.000032852862,0.000068143054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015920842,0.00026581888,0.00017665028,0.0003888551,0.00017952455,0.0001472334,0.00013478313,0.00032436254,0.0011006068],"category_scores_gemma":[0.0008283854,0.00010434659,0.00019634546,0.00021350449,0.0003609744,0.00009061815,0.00021239063,0.00018001033,0.00016393547],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010300225,0.0001232232,0.48999155,0.00015922789,0.00014408327,0.13118847,0.00047869532,0.00097145286,0.34634078,0.0008772412,0.0010840194,0.027611272],"study_design_scores_gemma":[0.00006462079,0.0007629676,0.45398057,0.000024885467,0.0001187397,0.48506042,0.00029341047,0.0020197842,0.053509057,0.0005853626,0.0035581205,0.00002194102],"about_ca_topic_score_codex":0.00049343845,"about_ca_topic_score_gemma":0.00071663765,"teacher_disagreement_score":0.0011006068,"about_ca_system_score_codex":0.00021274916,"about_ca_system_score_gemma":0.00018306261,"threshold_uncertainty_score":0.0036818981},"labels":[],"label_agreement":null},{"id":"W2790767158","doi":"10.1172/jci97837","title":"Role of proNGF/p75 signaling in bladder dysfunction after spinal cord injury","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; NIH Office of the Director; Alzheimer's Drug Discovery Foundation","keywords":"Spinal cord injury; Medicine; Urothelium; Urinary bladder; Nerve growth factor; Urination; Hyperplasia; Spinal cord; Resiniferatoxin; Tyrosine hydroxylase; Urology; Internal medicine; Urinary system; Endocrinology; Pathology; Immunohistochemistry; TRPV1; Receptor","score_opus":0.09431700928332773,"score_gpt":0.43585058749597916,"score_spread":0.3415335782126514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790767158","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756599,0.020287614,0.0018343234,0.0002747028,0.00003296894,0.000024136238,0.000069558155,0.00006189103,0.0017549745],"genre_scores_gemma":[0.9946467,0.004320284,0.00046840456,0.000036695346,0.000015577,0.000009778722,0.000023301816,0.0000015348326,0.00047767282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999212,0.000016812612,0.0000052781024,0.000008489792,0.000017032107,0.000031218937],"domain_scores_gemma":[0.9999455,0.0000071062136,0.000016872276,0.00000294474,0.0000066582484,0.000020789503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014240143,0.00035373826,0.0002488151,0.0002235261,0.00023908727,0.00027089365,0.00015056453,0.00024913606,0.0005209533],"category_scores_gemma":[0.0001313657,0.00005217952,0.00012413264,0.00014679966,0.0003973731,0.00021685645,0.00022113706,0.00048534406,0.0000776146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000879087,0.00012542563,0.0022876414,0.00034741382,0.000021866348,0.0010752105,0.00009415347,0.00027813498,0.96886146,0.0003703089,0.00012225592,0.02553704],"study_design_scores_gemma":[0.000073480864,0.0046379794,0.08688546,0.00011854546,0.00016570116,0.0038658753,0.00039257258,0.0014709578,0.8967051,0.0005494765,0.0051077534,0.000027166385],"about_ca_topic_score_codex":0.0010281953,"about_ca_topic_score_gemma":0.0015813035,"teacher_disagreement_score":0.0010281953,"about_ca_system_score_codex":0.0002938557,"about_ca_system_score_gemma":0.0004400432,"threshold_uncertainty_score":0.0021320581},"labels":[],"label_agreement":null},{"id":"W2792335811","doi":"10.1172/jci96174","title":"LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Universitätsspital Zürich; Canadian Institutes of Health Research; China Scholarship Council; Inselspital, Universitätsspital Bern; Swiss Transplant Cohort Study; University of Alberta; Universitätsspital Basel; Centre Hospitalier Universitaire Vaudois; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Biology; Major histocompatibility complex; Nonsynonymous substitution; Human leukocyte antigen; Mutation; Gene; Genetics; Antigen","score_opus":0.0503997508516832,"score_gpt":0.3453212717236818,"score_spread":0.29492152087199863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792335811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9996352,0.000086872984,0.00008534315,0.0000067043006,0.0000013774875,0.0000013801542,0.000020438627,0.0000032438065,0.0001593479],"genre_scores_gemma":[0.9997104,0.000020039388,0.000039380553,0.000007435945,0.0000021931114,0.0000017373973,0.000030894473,0.000003676499,0.00018426702],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9997949,0.000054239412,0.000014942606,0.000051525232,0.000026786338,0.00005766107],"domain_scores_gemma":[0.99973375,0.000075331904,0.000080095764,0.000017494702,0.000011391098,0.00008184261],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016329753,0.00016573192,0.00019710176,0.00017266998,0.00009666886,0.00028209403,0.00010587478,0.00022729808,0.0024753627],"category_scores_gemma":[0.00037755008,0.00008209152,0.0001141866,0.00013500667,0.00014368533,0.000111945184,0.00012102701,0.0003169493,0.00027357164],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00400812,0.00031832527,0.22151683,0.000027719383,0.000073819094,0.00070266984,0.0002132554,0.00027150908,0.7637608,0.00018893724,0.00013797998,0.008779998],"study_design_scores_gemma":[0.000048623966,0.0015027676,0.91137964,0.000008915371,0.0001044819,0.003569509,0.0001586716,0.0015134205,0.080429725,0.00014935528,0.0011185304,0.000016451228],"about_ca_topic_score_codex":0.00032683156,"about_ca_topic_score_gemma":0.00026370882,"teacher_disagreement_score":0.0024753627,"about_ca_system_score_codex":0.00013621105,"about_ca_system_score_gemma":0.000086316395,"threshold_uncertainty_score":0.008280873},"labels":[],"label_agreement":null},{"id":"W2793556683","doi":"10.1172/jci95127","title":"The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"National Institutes of Health; Canadian Institutes of Health Research; Agence Nationale de Recherches sur le Sida et les Hépatites Virales","keywords":"Simian immunodeficiency virus; CD8; Apoptosis; Immunology; Cytotoxic T cell; T cell; Immune system; Viral load; Programmed cell death; Virology; Biology; Virus; In vitro","score_opus":0.05593114888946106,"score_gpt":0.40678314281926753,"score_spread":0.3508519939298065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793556683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978331,0.0012752531,0.00030356488,0.000038690054,0.000014482006,0.000022736423,0.000049808474,0.000031535077,0.00043079173],"genre_scores_gemma":[0.9967894,0.0008074844,0.0009631016,0.000034941706,0.00001412594,0.000028551409,0.00012151911,0.0000065940662,0.0012342981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999294,0.000015866719,0.0000054710536,0.00001145248,0.0000115464,0.00002620879],"domain_scores_gemma":[0.999913,0.000018352988,0.000020858532,0.000009794115,0.000012318711,0.000025766749],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014224144,0.00021972532,0.00025119085,0.00023992786,0.0001442966,0.00020752623,0.00020048583,0.00026317156,0.0007268882],"category_scores_gemma":[0.00016653539,0.000096740514,0.00013062311,0.000055624343,0.00022914985,0.00014872866,0.00011756519,0.00042771295,0.00014514956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085641496,0.00036732008,0.0004941215,0.000055454133,0.000008681255,0.00008282104,0.000044987813,0.000087378736,0.9896382,0.000087437256,0.00007866895,0.008198408],"study_design_scores_gemma":[0.00030718883,0.015547588,0.01923758,0.000032790533,0.000065162276,0.00070189056,0.00012097161,0.002760055,0.95651186,0.00020627478,0.0044943984,0.000014346231],"about_ca_topic_score_codex":0.00091307773,"about_ca_topic_score_gemma":0.0014742616,"teacher_disagreement_score":0.00091307773,"about_ca_system_score_codex":0.0001476839,"about_ca_system_score_gemma":0.00024596442,"threshold_uncertainty_score":0.002431631},"labels":[],"label_agreement":null},{"id":"W2796425507","doi":"10.1172/jci97098","title":"Humanized mouse model of Rasmussen’s encephalitis supports the immune-mediated hypothesis","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; Centre Hospitalier Universitaire Sainte-Justine; Centre Hospitalier Universitaire de Sherbrooke; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Astrogliosis; Hemispherectomy; Medicine; Immunology; Immune system; Humanized mouse; Multiple sclerosis; Encephalitis; Epilepsy; Pathology; Central nervous system; Internal medicine","score_opus":0.2255524104533053,"score_gpt":0.4156244015959532,"score_spread":0.19007199114264792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796425507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8926408,0.025122406,0.03780041,0.0095182145,0.0013738709,0.0004609384,0.0026388974,0.0019757417,0.028468672],"genre_scores_gemma":[0.95843244,0.012907544,0.01198045,0.0016767123,0.0002643905,0.0003736195,0.0016954952,0.000089998764,0.012579409],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947864,0.00017048804,0.00004635019,0.00012620646,0.000104733845,0.000073636635],"domain_scores_gemma":[0.9995778,0.00010836507,0.000101275014,0.000102270824,0.000053455595,0.00005670848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011262794,0.0011325328,0.0006105667,0.0009862178,0.00032910562,0.00064281723,0.00059263373,0.0012203255,0.0041548605],"category_scores_gemma":[0.000474202,0.00023513894,0.0005567176,0.00027313278,0.0009476308,0.00091462064,0.00036052885,0.0018353427,0.0010914125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011623203,0.00075706805,0.0013360102,0.0004225507,0.00009064149,0.0018811167,0.00011567933,0.00023162834,0.976784,0.0053628692,0.0021883543,0.00966785],"study_design_scores_gemma":[0.00072222337,0.007942449,0.010601705,0.00044464433,0.00045355147,0.025509464,0.00024466007,0.004252664,0.8689433,0.006299227,0.07450255,0.00008363145],"about_ca_topic_score_codex":0.00043820866,"about_ca_topic_score_gemma":0.0005354719,"teacher_disagreement_score":0.0041548605,"about_ca_system_score_codex":0.0003921898,"about_ca_system_score_gemma":0.00033453968,"threshold_uncertainty_score":0.013899386},"labels":[],"label_agreement":null},{"id":"W2796581040","doi":"10.1172/jci98814","title":"JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":521,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre","funders":"National Institute of Allergy and Infectious Diseases; Rosetrees Trust; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Eli Lilly and Company","keywords":"Medicine; Internal medicine","score_opus":0.05548603744449432,"score_gpt":0.34178881645158027,"score_spread":0.28630277900708595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796581040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97116345,0.025042098,0.00045179977,0.00044335113,0.00007322731,0.00007736197,0.00019139914,0.00005868681,0.0024984614],"genre_scores_gemma":[0.99394727,0.004456019,0.0005513654,0.00017974144,0.000047238987,0.000046462414,0.0002891871,0.0000057935654,0.0004768917],"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.9999032,0.000022225819,0.0000113050155,0.000011726579,0.000020946836,0.000030505962],"domain_scores_gemma":[0.99988174,0.00002552117,0.00004723502,0.0000071791337,0.000014496469,0.000023756016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037476723,0.0002585531,0.0003609075,0.00020297013,0.00013406965,0.00028470246,0.00020240252,0.00018897287,0.0009526545],"category_scores_gemma":[0.00024064747,0.00005740971,0.00023357393,0.00017715631,0.000120536955,0.0001403224,0.00015814115,0.0006222732,0.00015274371],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.031025471,0.003008142,0.030308183,0.0016315338,0.00092041906,0.0019768975,0.00025779678,0.0062006977,0.25389218,0.0011727158,0.007324349,0.6622817],"study_design_scores_gemma":[0.04372993,0.08860278,0.39498472,0.0011986984,0.003037299,0.024511969,0.0003946823,0.025904842,0.30956215,0.0018181115,0.10607288,0.000181965],"about_ca_topic_score_codex":0.0003909233,"about_ca_topic_score_gemma":0.0016667998,"teacher_disagreement_score":0.0009526545,"about_ca_system_score_codex":0.00042555283,"about_ca_system_score_gemma":0.0002909237,"threshold_uncertainty_score":0.0031869411},"labels":[],"label_agreement":null},{"id":"W2797791176","doi":"10.1172/jci95305","title":"CNS myeloid cells critically regulate heat hyperalgesia","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fraunhofer-Institut für Zelltherapie und Immunologie; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medicine; University of Toronto","keywords":"Myeloid cells; Myeloid; Hyperalgesia; Chemistry; Medicine; Neuroscience; Cell biology; Immunology; Biology; Biochemistry; Receptor; Nociception","score_opus":0.11526936522011824,"score_gpt":0.3669373391501598,"score_spread":0.2516679739300416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797791176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929953,0.0043200864,0.0008923156,0.0001232112,0.000023545046,0.00004740928,0.0001398315,0.000038067297,0.0014202358],"genre_scores_gemma":[0.99678075,0.0016383759,0.0005943285,0.000041356932,0.000020586882,0.000038570153,0.000088251516,0.000008811834,0.00078894704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998653,0.000029054641,0.0000132673695,0.000018767641,0.00002417261,0.00004942559],"domain_scores_gemma":[0.99990857,0.00001050518,0.00003376437,0.000009525077,0.0000121306,0.00002544586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016627026,0.0002634402,0.00027274166,0.00017697821,0.00017418405,0.00032117803,0.00013561657,0.00023349177,0.0012655739],"category_scores_gemma":[0.00014450423,0.0000922885,0.00015560933,0.000087012406,0.00048290635,0.00025066693,0.00030091943,0.0005535674,0.00028864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000418182,0.000024337805,0.00052007864,0.000056882454,0.0000027011486,0.00013292534,0.00003751631,0.000033037093,0.9963648,0.00021970428,0.00004006259,0.0021497046],"study_design_scores_gemma":[0.0001268814,0.0011114896,0.059046358,0.000069679525,0.00007052119,0.001367228,0.00031191824,0.0009222937,0.9307486,0.00073770905,0.0054706326,0.000016572956],"about_ca_topic_score_codex":0.00021313228,"about_ca_topic_score_gemma":0.00036878858,"teacher_disagreement_score":0.0012655739,"about_ca_system_score_codex":0.00028207898,"about_ca_system_score_gemma":0.00022600061,"threshold_uncertainty_score":0.0042337775},"labels":[],"label_agreement":null},{"id":"W2799869022","doi":"10.1172/jci95476","title":"Metreleptin-mediated improvements in insulin sensitivity are independent of food intake in humans with lipodystrophy","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; NIH Clinical Center; National Institutes of Health","keywords":"Lipodystrophy; Leptin; Endocrinology; Internal medicine; Insulin sensitivity; Insulin; Medicine; Insulin resistance; Food intake; Obesity; Immunology","score_opus":0.07157868493419671,"score_gpt":0.33112564345042655,"score_spread":0.25954695851622983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2799869022","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991215,0.00043101347,0.00017923058,0.000023737006,0.0000058511814,0.000029780284,0.000040282044,0.0000070977303,0.00016148783],"genre_scores_gemma":[0.9988826,0.00024581354,0.00041640966,0.000056361445,0.000015506022,0.000057495992,0.00015408281,0.0000035907965,0.00016814277],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99977237,0.00008903359,0.000025312165,0.000048564118,0.000037419803,0.000027312888],"domain_scores_gemma":[0.99970055,0.00005550571,0.00012083692,0.000048977072,0.0000127585345,0.00006141731],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000567493,0.00048054452,0.0007084038,0.00024011642,0.0002536773,0.00028456136,0.00020700155,0.00033116274,0.0011041395],"category_scores_gemma":[0.0006923969,0.00023732666,0.00033780598,0.0001934471,0.00047848627,0.000242258,0.00020572789,0.0006356218,0.00017320194],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.15556929,0.008084752,0.21024053,0.00051711826,0.00069859426,0.0036863056,0.00037147023,0.00058344513,0.54432243,0.00018408638,0.0006928048,0.07504914],"study_design_scores_gemma":[0.0074745584,0.08633065,0.8699013,0.00004019841,0.0003792357,0.009953303,0.00017315202,0.00093183096,0.022484181,0.00026188273,0.0020300215,0.000039701605],"about_ca_topic_score_codex":0.00015488265,"about_ca_topic_score_gemma":0.00023012045,"teacher_disagreement_score":0.0011041395,"about_ca_system_score_codex":0.0002027469,"about_ca_system_score_gemma":0.00017898358,"threshold_uncertainty_score":0.0036937594},"labels":[],"label_agreement":null},{"id":"W2805419050","doi":"10.1172/jci96640","title":"Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Kidney Injury Research","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Calgary; Libin Cardiovascular Institute of Alberta","funders":"Canadian Institutes of Health Research; University of Calgary; Alberta Innovates; Alberta Health Services; European Commission; Alberta Innovates - Health Solutions","keywords":"Inflammasome; Acute kidney injury; Kidney; Dipeptidase; Inflammation; Medicine; Pathology; Reabsorption; Renal physiology; Internal medicine; Chemistry; Biochemistry","score_opus":0.06760623114428854,"score_gpt":0.4228463846779157,"score_spread":0.35524015353362715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805419050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9733097,0.015093643,0.008691628,0.00047197627,0.00007598714,0.00013121366,0.00015023202,0.00020519798,0.0018704017],"genre_scores_gemma":[0.9928368,0.0028855372,0.0025548963,0.00023639614,0.000078680176,0.000052640928,0.00012575478,0.000022388163,0.0012068679],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995278,0.00008600663,0.00006282875,0.00009868093,0.00011072681,0.00011399276],"domain_scores_gemma":[0.99928814,0.000033422573,0.00037040008,0.00005009682,0.000059970513,0.00019804403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044977266,0.0008068725,0.00070418784,0.00056279707,0.00020469652,0.0006852298,0.00031759174,0.00069348386,0.0011129513],"category_scores_gemma":[0.0004773146,0.00030846833,0.00057737867,0.00018416296,0.0005406685,0.00046710225,0.00073269923,0.0013147027,0.00028383275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018096869,0.00022791213,0.007404271,0.0004044999,0.00005683774,0.0010813769,0.000095460666,0.00015033889,0.97495097,0.0005678616,0.00020936424,0.013041376],"study_design_scores_gemma":[0.00029143825,0.0030449985,0.20782134,0.00015223968,0.0004100808,0.009218626,0.00031745998,0.0052791657,0.76254743,0.00198079,0.008879215,0.000057278732],"about_ca_topic_score_codex":0.00019555812,"about_ca_topic_score_gemma":0.00016848318,"teacher_disagreement_score":0.0011129513,"about_ca_system_score_codex":0.00038139822,"about_ca_system_score_gemma":0.0003522866,"threshold_uncertainty_score":0.0037231445},"labels":[],"label_agreement":null},{"id":"W2806888518","doi":"10.1172/jci94003","title":"A review of current theories and treatments for phantom limb pain","year":2018,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pain Management and Treatment","field":"Medicine","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Health Science Center, University of Tennessee; U.S. Department of Veterans Affairs","keywords":"Phantom limb; Phantom limb pain; Amputation; Phantom pain; Feeling; Dorsal root ganglion; Physical medicine and rehabilitation; Neuroscience; Medicine; Peripheral nervous system; Nervous system; Quality of life (healthcare); Central nervous system; Dorsum; Psychology; Surgery; Anatomy","score_opus":0.31920409113247605,"score_gpt":0.53292715202675,"score_spread":0.21372306089427395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806888518","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000069796515,0.9985599,0.00009715603,0.00028104344,0.00015064304,0.0000070664823,0.0000257712,0.000006705825,0.00080201257],"genre_scores_gemma":[0.0003700405,0.99881953,0.00020805452,0.00018847371,0.00014614806,0.000008421669,0.00002784429,0.0000013101851,0.00023015484],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.99965346,0.000066647364,0.000084804684,0.00005748919,0.000115852265,0.000021712658],"domain_scores_gemma":[0.9992106,0.0004868307,0.00011034712,0.000017061184,0.0001361218,0.000039000814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069047534,0.0010316382,0.0014586145,0.0039354167,0.00049391045,0.0011546402,0.0011682481,0.0012234196,0.008936536],"category_scores_gemma":[0.0018968767,0.00035000656,0.00096435874,0.0027746984,0.00056072813,0.001702814,0.0007198526,0.0018952216,0.0026122648],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067722234,0.00010174469,0.00019742653,0.047709912,0.00012229639,0.00030711666,0.00012007185,0.0001840783,0.00066993566,0.0025837338,0.034979828,0.9129561],"study_design_scores_gemma":[0.000025275034,0.00014229327,0.001020478,0.024150841,0.00036082018,0.0030727242,0.0001408477,0.00007866736,0.0003128785,0.0024251922,0.9682363,0.000033656186],"about_ca_topic_score_codex":0.0013171266,"about_ca_topic_score_gemma":0.0022445428,"teacher_disagreement_score":0.008936536,"about_ca_system_score_codex":0.0005825462,"about_ca_system_score_gemma":0.0015788001,"threshold_uncertainty_score":0.029895663},"labels":[],"label_agreement":null},{"id":"W2808207128","doi":"10.1172/jci97116","title":"Inherited p40phox deficiency differs from classic chronic granulomatous disease","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"NHLBI Division of Intramural Research; National Center for Research Resources; National Cancer Institute; Canadian Institutes of Health Research; National Center for Advancing Translational Sciences; Consejo Nacional de Ciencia y Tecnología; Agence Nationale de la Recherche; National Institutes of Health; U.S. Department of Health and Human Services; Japan Foundation for Pediatric Research; Lastentautien Tutkimussäätiö; Institut des maladies génétiques Imagine; Leona M. and Harry B. Helmsley Charitable Trust; Institut National de la Santé et de la Recherche Médicale; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; National Institute of Allergy and Infectious Diseases; Université Paris Descartes; St. Giles Foundation; Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Chronic granulomatous disease; NADPH oxidase; Compound heterozygosity; Biology; Oxidase test; Aspergillus fumigatus; Phagocyte; Immunology; Mutation; Candida albicans; Microbiology; Gene; Phagocytosis; Genetics; Enzyme; Reactive oxygen species; Biochemistry","score_opus":0.055779874915194906,"score_gpt":0.3287580882557917,"score_spread":0.2729782133405968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808207128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99818474,0.0004066455,0.00024130198,0.000036080277,0.000007547893,0.00001235045,0.00009849919,0.000021378079,0.0009914117],"genre_scores_gemma":[0.9990308,0.00018460488,0.0003113175,0.000048947997,0.000018375711,0.000009809469,0.00012827342,0.000010270866,0.0002575577],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9996737,0.0000372269,0.00004137701,0.00011318434,0.00005208036,0.00008247649],"domain_scores_gemma":[0.9995054,0.00012121379,0.00014053566,0.000038973496,0.000029751269,0.00016408705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017522034,0.000999256,0.00041934696,0.0010484064,0.00047924055,0.00040443696,0.00027101504,0.00069361465,0.0026143019],"category_scores_gemma":[0.0011197866,0.00030545986,0.0002475166,0.00079821976,0.0005917571,0.00028207764,0.00068849814,0.0003140054,0.00028815473],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00184716,0.00025506163,0.46186963,0.0003903588,0.00025307047,0.32549986,0.0019683386,0.0003939081,0.17558493,0.0014680752,0.0009888856,0.029480817],"study_design_scores_gemma":[0.00015114275,0.00035526964,0.35911983,0.000060943035,0.0001344921,0.6304235,0.00033494277,0.00023532062,0.0055956487,0.00042885303,0.003132862,0.00002714162],"about_ca_topic_score_codex":0.0008342627,"about_ca_topic_score_gemma":0.00092396507,"teacher_disagreement_score":0.0026143019,"about_ca_system_score_codex":0.00023967109,"about_ca_system_score_gemma":0.00025095505,"threshold_uncertainty_score":0.00874567},"labels":[],"label_agreement":null},{"id":"W2867385468","doi":"10.1172/jci121744","title":"Vaginal epidermal dendritic cells: defense against HIV-1 or a safe haven?","year":2018,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Sex work and related issues","field":"Social Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"University of Toronto","keywords":"Langerin; Birbeck granules; Biology; Immunology; Virology; Lectin; Human immunodeficiency virus (HIV); Viral load; Viral replication; Langerhans cell; Dendritic cell; Virus; Immune system","score_opus":0.10257346570788964,"score_gpt":0.3952142316996396,"score_spread":0.29264076599174993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2867385468","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0074576163,0.011471509,0.00026766543,0.9652807,0.0083826035,0.00001642869,0.000019404453,0.000025437706,0.007078596],"genre_scores_gemma":[0.14114341,0.021488063,0.0008545306,0.7491929,0.06536227,0.000054074993,0.000039129547,0.000022305574,0.021843316],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994487,0.00020905382,0.00005435571,0.000059219205,0.00011864037,0.00010998905],"domain_scores_gemma":[0.99892575,0.0005897842,0.00008269956,0.000053442225,0.00017261795,0.00017564557],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007744554,0.00030761166,0.00058300723,0.00026172926,0.0014061006,0.0013045968,0.0005273658,0.013361717,0.0038314697],"category_scores_gemma":[0.004052875,0.0001675324,0.00032872433,0.00018942314,0.0013673414,0.0023004506,0.0006415087,0.010452042,0.0025650691],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003144176,0.00028254694,0.013740291,0.00045474543,0.000040562067,0.13117315,0.0019947963,0.00014978046,0.0031791353,0.032876525,0.69166017,0.1241339],"study_design_scores_gemma":[0.00014625976,0.00023275394,0.0031354523,0.0007106069,0.000025556354,0.101888105,0.003976928,0.00055866945,0.0007297633,0.02920585,0.8593472,0.000042888398],"about_ca_topic_score_codex":0.00073329295,"about_ca_topic_score_gemma":0.001085588,"teacher_disagreement_score":0.013361717,"about_ca_system_score_codex":0.0011510234,"about_ca_system_score_gemma":0.0006413271,"threshold_uncertainty_score":0.012817562},"labels":[],"label_agreement":null},{"id":"W2883258608","doi":"10.1172/jci98093","title":"Optimal bone fracture repair requires 24R,25-dihydroxyvitamin D3 and its effector molecule FAM57B2","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Queen's University; McGill University","funders":"National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Shriners Hospitals for Children; Queen's University; McGill University","keywords":"Endochondral ossification; Callus; Cartilage; CYP24A1; Bone healing; Cell biology; Chemistry; Chondrocyte; Biology; Anatomy; Botany; Biochemistry; Gene; Calcitriol receptor","score_opus":0.03263693628454834,"score_gpt":0.3463395909982751,"score_spread":0.31370265471372677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883258608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92906696,0.021946898,0.035087124,0.001072252,0.000261717,0.00022428881,0.0016066994,0.00071093906,0.010023105],"genre_scores_gemma":[0.9446835,0.00739983,0.026467878,0.00066914904,0.000069355636,0.000205795,0.0020080244,0.0001221976,0.01837431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99972516,0.000022158058,0.000027601749,0.00007634538,0.000090665926,0.000058020163],"domain_scores_gemma":[0.9998933,0.00001554199,0.00002431873,0.000021327196,0.000019052506,0.000026445708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025315853,0.00036723106,0.00044116733,0.00036157368,0.00040625446,0.0006412611,0.0003396204,0.0005611018,0.002311135],"category_scores_gemma":[0.00012948098,0.00027589028,0.00050629076,0.00018735905,0.00033168474,0.0003585525,0.00049564365,0.00079208915,0.0015425186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058393605,0.00001767293,0.00037792427,0.00004156933,0.0000031937225,0.00015213175,0.0000096346275,0.000041540836,0.9956163,0.00019103134,0.00008762659,0.0034029845],"study_design_scores_gemma":[0.00002740745,0.00011784004,0.0045073456,0.000009129071,0.000014318023,0.00068480225,0.000034835644,0.00059405336,0.98510724,0.000092633985,0.008800404,0.000010033114],"about_ca_topic_score_codex":0.00078430487,"about_ca_topic_score_gemma":0.001171698,"teacher_disagreement_score":0.002311135,"about_ca_system_score_codex":0.00059261674,"about_ca_system_score_gemma":0.0002747259,"threshold_uncertainty_score":0.007731557},"labels":[],"label_agreement":null},{"id":"W2883804067","doi":"10.1172/jci120549","title":"HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; ACT Government; Brigham and Women's Hospital; Gilead Sciences; Harvard University; Harvard University Center for AIDS Research; Center for AIDS Research, University of Washington; Michael Smith Health Research BC; GlaxoSmithKline","keywords":"Genome; Biology; Peripheral blood mononuclear cell; CD8; Immune system; Human immunodeficiency virus (HIV); Virology; Virus; Immunology; Acquired immune system; Viral load; Gene; Genetics","score_opus":0.04762824174676433,"score_gpt":0.3526739322880203,"score_spread":0.30504569054125596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883804067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99920195,0.00009225335,0.00015086275,0.0000055793853,0.0000011851519,0.000016210193,0.00010085869,0.000008339042,0.0004228055],"genre_scores_gemma":[0.9993605,0.000033747925,0.0001822408,0.000010119956,0.0000019292604,0.000010442004,0.00019869005,0.0000036793715,0.00019863737],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99984455,0.000016039197,0.000011190332,0.000038178503,0.000041603424,0.000048351067],"domain_scores_gemma":[0.99965596,0.000100434954,0.00008170803,0.000036771842,0.000051986342,0.0000730983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021276985,0.00012790997,0.00019428019,0.0007474929,0.0002891151,0.00064246537,0.00020315094,0.0003528886,0.001997603],"category_scores_gemma":[0.0007964836,0.0001293799,0.000092525006,0.00025255512,0.00023734137,0.00036720728,0.00024938298,0.00026355576,0.00016702329],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002344798,0.0003606569,0.7202324,0.00007563584,0.000043355918,0.0006542167,0.0007201602,0.00045916295,0.23463833,0.0003082129,0.0002951322,0.039867993],"study_design_scores_gemma":[0.000025764388,0.0009796971,0.97600865,0.000012823878,0.000034729303,0.0016701041,0.0005462218,0.002465386,0.017324062,0.0002655648,0.0006528662,0.000014126527],"about_ca_topic_score_codex":0.0018188988,"about_ca_topic_score_gemma":0.0031533556,"teacher_disagreement_score":0.001997603,"about_ca_system_score_codex":0.00027628485,"about_ca_system_score_gemma":0.00015784182,"threshold_uncertainty_score":0.0066825747},"labels":[],"label_agreement":null},{"id":"W2883909768","doi":"10.1172/jci99315","title":"Endothelial cell CD36 optimizes tissue fatty acid uptake","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":256,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; York University; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Washington; NYU Langone Medical Center","keywords":"CD36; Adipose tissue; Internal medicine; Endocrinology; Glucose uptake; Insulin; Lipotoxicity; Parenchyma; Biology; Fatty acid; Lipid metabolism; Cell; Endothelial stem cell; Chemistry; Receptor; Insulin resistance; Biochemistry; Medicine; In vitro","score_opus":0.08854056074036706,"score_gpt":0.390938343573742,"score_spread":0.30239778283337493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883909768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9880157,0.002839334,0.006111481,0.0003301873,0.00006233309,0.000026489972,0.000256088,0.00016356325,0.002194806],"genre_scores_gemma":[0.9907574,0.000999037,0.0045828773,0.00010451038,0.0000199105,0.000021540665,0.00028274802,0.0000359312,0.0031959473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997625,0.000047755224,0.000021028947,0.00005928391,0.000043126223,0.00006631807],"domain_scores_gemma":[0.9998481,0.000021210459,0.00003294973,0.000019511872,0.000030209281,0.000048067242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002545915,0.0002220807,0.00044671335,0.00015692489,0.00019090508,0.00056367344,0.00024978776,0.00036356598,0.0015903853],"category_scores_gemma":[0.00022868082,0.00013849093,0.00017499477,0.0001823254,0.00020231742,0.000322641,0.0003550268,0.0006720018,0.00061463565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036353344,0.000048996066,0.00042543744,0.000050799867,0.0000065956474,0.000036297,0.000017038918,0.00012685098,0.9953668,0.00023540686,0.00015084023,0.0031713636],"study_design_scores_gemma":[0.000054731885,0.00028266502,0.0025086598,0.00000849335,0.00004248384,0.00022853089,0.000038335224,0.0017354952,0.98857075,0.000113785834,0.006409879,0.0000061817427],"about_ca_topic_score_codex":0.00091752986,"about_ca_topic_score_gemma":0.0010643202,"teacher_disagreement_score":0.0015903853,"about_ca_system_score_codex":0.00035400782,"about_ca_system_score_gemma":0.00034100996,"threshold_uncertainty_score":0.0053203106},"labels":[],"label_agreement":null},{"id":"W2886206473","doi":"10.1172/jci96400","title":"The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Immunogenicity; Receptor; Cell biology; Endothelium; Endothelial stem cell; Cell; Chemistry; Biology; Immunology; Biochemistry; Antibody; Endocrinology","score_opus":0.08506243811609118,"score_gpt":0.36383178208642114,"score_spread":0.27876934397032993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886206473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939573,0.0023676893,0.0022555168,0.000073949064,0.000023076707,0.000010591496,0.00013113029,0.00006112751,0.0011196077],"genre_scores_gemma":[0.9968966,0.0005823517,0.0007130867,0.000023776527,0.000009801776,0.000012506356,0.00015650495,0.000015344225,0.0015900496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989843,0.000021422318,0.000008396632,0.000023023485,0.000020699916,0.00002799788],"domain_scores_gemma":[0.99983644,0.000021136104,0.000050342474,0.000011646824,0.000027584032,0.000052940715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012672544,0.00022845723,0.00016814022,0.00022630207,0.00017254672,0.00049263315,0.0001490629,0.00025077187,0.0011495446],"category_scores_gemma":[0.00019810637,0.00013148726,0.00015934008,0.00011031246,0.00018391902,0.00025328746,0.00024188713,0.0003501975,0.00046843433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015878238,0.0000128287575,0.0006115645,0.000007849888,0.000002914509,0.00005104916,0.000010577463,0.00007194081,0.9978522,0.00016528291,0.000042554715,0.0010123522],"study_design_scores_gemma":[0.000060697123,0.00030581167,0.03920149,0.000010565802,0.00003789797,0.0006329214,0.00009532675,0.005860158,0.948221,0.00032447634,0.0052311425,0.000018448061],"about_ca_topic_score_codex":0.00033544254,"about_ca_topic_score_gemma":0.00030729306,"teacher_disagreement_score":0.0011495446,"about_ca_system_score_codex":0.00029133368,"about_ca_system_score_gemma":0.00015297139,"threshold_uncertainty_score":0.0038455725},"labels":[],"label_agreement":null},{"id":"W2886930165","doi":"10.1172/jci121960","title":"Circulating and intrahepatic antiviral B cells are defective in hepatitis B","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":326,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; National Institute for Health and Care Research; Gilead Sciences; Wellcome Trust; F. Hoffmann-La Roche; Roche","keywords":"HBsAg; Hepatitis B virus; Antibody; Immunology; Hepatitis B; Antigen; Biology; Virology; B cell; Medicine; Virus","score_opus":0.080721254435213,"score_gpt":0.3812247071006864,"score_spread":0.3005034526654734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886930165","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977992,0.00080048846,0.00042702936,0.000041217507,0.000011884278,0.0000145708955,0.00013656229,0.000048070182,0.0007208805],"genre_scores_gemma":[0.99789727,0.00021108403,0.00032061478,0.000034832537,0.000009014728,0.00001720249,0.0002240443,0.000015613889,0.0012702722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985373,0.00002694472,0.000017074479,0.000034506458,0.000030990625,0.000036784593],"domain_scores_gemma":[0.9998543,0.000023502176,0.000023120427,0.000026791737,0.000012966082,0.00005923194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021527821,0.00023624998,0.00028332608,0.0004159297,0.00017928335,0.00033267023,0.00015290373,0.00033624537,0.002928224],"category_scores_gemma":[0.00025260713,0.00018312459,0.00012235239,0.0001637983,0.00035151668,0.00023079393,0.00022099796,0.0005665184,0.0008117023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007334435,0.00018224347,0.0047355955,0.000070153925,0.000010100599,0.00040187585,0.00008052412,0.000040163868,0.98687905,0.00025565704,0.00009473322,0.006516442],"study_design_scores_gemma":[0.00049008866,0.007105902,0.18115598,0.000052738204,0.00011522985,0.020980204,0.00055098895,0.0015883697,0.77122635,0.0009919277,0.015717072,0.000025128133],"about_ca_topic_score_codex":0.000205306,"about_ca_topic_score_gemma":0.00016605557,"teacher_disagreement_score":0.002928224,"about_ca_system_score_codex":0.00012498997,"about_ca_system_score_gemma":0.00010101621,"threshold_uncertainty_score":0.009795904},"labels":[],"label_agreement":null},{"id":"W2887450160","doi":"10.1172/jci98199","title":"Activity-dependent neuroprotective protein deficiency models synaptic and developmental phenotypes of autism-like syndrome","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"CIHR Skin Research Training Centre; European Regional Development Fund; Canadian Institutes of Health Research; Israel Science Foundation; Ministerstvo Školství, Mládeže a Tělovýchovy; McGill University; National Science Foundation; Tel Aviv University; ERA-Net NEURON","keywords":"Neuroprotection; Autism; Phenotype; Neuroscience; Biology; Medicine; Genetics; Gene; Psychiatry","score_opus":0.11171376338398041,"score_gpt":0.35900405317836037,"score_spread":0.24729028979437995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887450160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984665,0.0021277473,0.010059997,0.00021072374,0.00006668506,0.00018752544,0.0006884569,0.00031617034,0.0016777377],"genre_scores_gemma":[0.98458475,0.0031455369,0.008369692,0.00008362678,0.00002087595,0.00022986937,0.00076883857,0.00004496327,0.0027518126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997832,0.00003676937,0.00003761506,0.000048368853,0.00006363668,0.000030372956],"domain_scores_gemma":[0.999887,0.000013029042,0.00003973635,0.00001243356,0.000010232505,0.000037607344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019826226,0.0008070916,0.00035727452,0.00075080286,0.0002658716,0.00020120032,0.00040104575,0.00052918406,0.0010824667],"category_scores_gemma":[0.000118725795,0.00019174276,0.000298456,0.00021258634,0.0005682979,0.00028388636,0.00036255378,0.0007380275,0.00031730966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000098223136,0.00008850741,0.0003369595,0.000051625622,0.000009789055,0.0002533289,0.000019849747,0.00007126157,0.9973247,0.00023507113,0.000064942025,0.0014458115],"study_design_scores_gemma":[0.00008189166,0.0018453111,0.007867654,0.00003304125,0.000067592366,0.0032387592,0.00011430763,0.002660765,0.9780292,0.00034759325,0.0056951116,0.000018876604],"about_ca_topic_score_codex":0.0006819613,"about_ca_topic_score_gemma":0.0014813027,"teacher_disagreement_score":0.0010824667,"about_ca_system_score_codex":0.0002880539,"about_ca_system_score_gemma":0.0002649038,"threshold_uncertainty_score":0.0036212802},"labels":[],"label_agreement":null},{"id":"W2890056446","doi":"10.1172/jci99317","title":"Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":827,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Immunotherapy; Blockade; Cancer immunotherapy; Cancer research; PD-L1; Immunology; Immune checkpoint; Biology; Immune system; Lymphokine-activated killer cell; T cell; Interleukin 21; In vitro; Receptor","score_opus":0.031063308405792984,"score_gpt":0.3320367425043094,"score_spread":0.30097343409851646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890056446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835015,0.008864437,0.003050484,0.0003095753,0.000113827096,0.00011562381,0.000048486396,0.00010846118,0.00388768],"genre_scores_gemma":[0.9968129,0.0014299212,0.00082540145,0.0000971918,0.00004221511,0.000056772464,0.000031978947,0.00000774527,0.0006959917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99967504,0.00013079689,0.000029075276,0.000038025606,0.000051682477,0.00007537757],"domain_scores_gemma":[0.99985564,0.0000505016,0.00002622891,0.000021944521,0.000013064466,0.000032523334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041948134,0.00040756725,0.0006138708,0.00021341087,0.00012088652,0.0004916251,0.00020453421,0.00036583477,0.0007920219],"category_scores_gemma":[0.00032724094,0.00014371837,0.000253083,0.000062338506,0.00031813903,0.0003471184,0.0002423964,0.00094132137,0.00017547983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027838622,0.000835977,0.001883748,0.00036844608,0.00003381704,0.00029860015,0.00007032526,0.001179881,0.9459276,0.0015232624,0.00025699072,0.044837423],"study_design_scores_gemma":[0.0012010357,0.009694468,0.011318028,0.00010958391,0.0002979095,0.002605157,0.000104536186,0.00982451,0.950611,0.0013109256,0.012904834,0.000018002223],"about_ca_topic_score_codex":0.00009700572,"about_ca_topic_score_gemma":0.00013369089,"teacher_disagreement_score":0.0007920219,"about_ca_system_score_codex":0.00027275752,"about_ca_system_score_gemma":0.00037363174,"threshold_uncertainty_score":0.0026496053},"labels":[],"label_agreement":null},{"id":"W2891110262","doi":"10.1172/jci120401","title":"Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Tech University; Hôpital Maisonneuve-Rosemont; Princess Margaret Cancer Centre; Jewish General Hospital; University of Toronto; University Health Network","funders":"European Regional Development Fund; University Health Network; University of Toronto; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad; Generalitat de Catalunya","keywords":"Ubiquitin ligase; Notch signaling pathway; Cancer research; Carcinogenesis; Biology; Ubiquitin; Hes3 signaling axis; Signal transduction; DNA repair; Breast cancer; Cell biology; Cancer; Genetics; DNA; Gene","score_opus":0.046878078033136726,"score_gpt":0.33791089790248524,"score_spread":0.29103281986934854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891110262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989908,0.004922019,0.0029412983,0.00023447312,0.000047806403,0.000019692065,0.0002699989,0.000146434,0.0015102355],"genre_scores_gemma":[0.99644464,0.0005834515,0.0008602148,0.000050823848,0.00000654724,0.000009430687,0.00018614365,0.000014807067,0.0018439068],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983907,0.000032655844,0.0000139317635,0.00003169115,0.00003655489,0.000045968925],"domain_scores_gemma":[0.99987626,0.000012741441,0.000035093864,0.000017411234,0.000016875772,0.00004164186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019863028,0.00027130148,0.00023583567,0.00026946323,0.00011830438,0.00030156365,0.00020303381,0.00029166215,0.0009762411],"category_scores_gemma":[0.0001567006,0.00012236906,0.00022044823,0.00010491259,0.00018366228,0.00013521113,0.00014775785,0.00039405312,0.00029777983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028620355,0.00005234445,0.001028596,0.000031627904,0.00001265702,0.00013270929,0.000007741341,0.00008839991,0.9934683,0.00019216226,0.00012776861,0.004571525],"study_design_scores_gemma":[0.000041797317,0.00034421578,0.0107208835,0.000008821642,0.000027690592,0.0016306647,0.000037656548,0.0016862812,0.97804445,0.00014634249,0.007305508,0.000005762248],"about_ca_topic_score_codex":0.00052580005,"about_ca_topic_score_gemma":0.0011803085,"teacher_disagreement_score":0.0009762411,"about_ca_system_score_codex":0.0003738817,"about_ca_system_score_gemma":0.00023161044,"threshold_uncertainty_score":0.0032658577},"labels":[],"label_agreement":null},{"id":"W2891921574","doi":"10.1172/jci98688","title":"Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Harvard Stem Cell Institute; National Institutes of Health; Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften; National Heart, Lung, and Blood Institute; King Saud University; Deutsche Forschungsgemeinschaft; Higher Education Commision, Pakistan; Universität zu Köln; Boston Children's Hospital; Kidney Foundation of Canada; European Commission; Academy of Medical Sciences; Institut des maladies génétiques Imagine; Yale University; Canadian Society of Nephrology; National Human Genome Research Institute; Agence Nationale de la Recherche; Canadian Institutes of Health Research; American Society of Nephrology; University of Michigan","keywords":"Biology; Gene knockdown; Phenotype; Nuclear pore; Morpholino; Nucleoporin; Zebrafish; Nephrotic syndrome; Mutation; Genetics; Allele; Gene; Cell biology; Cancer research; Nuclear transport; Cell nucleus; Cytoplasm; Endocrinology","score_opus":0.15732150851707705,"score_gpt":0.3829316394708059,"score_spread":0.22561013095372884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891921574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99262977,0.0020713466,0.0036762413,0.000105238454,0.00003182981,0.00001675029,0.00018259654,0.00022024338,0.001065915],"genre_scores_gemma":[0.9958662,0.0012182439,0.0018947347,0.000047076202,0.000013809289,0.0000070734645,0.00020807356,0.00002070714,0.0007241432],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999025,0.000011176092,0.0000140436905,0.00002226284,0.000040497296,0.000009445795],"domain_scores_gemma":[0.99990666,0.000016127455,0.000041386098,0.0000057332218,0.000008254091,0.000021938735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006476373,0.00057267974,0.00027136152,0.00027937922,0.00015161668,0.00014421379,0.00017566048,0.00033338426,0.0007358459],"category_scores_gemma":[0.00015116311,0.00010579555,0.00020040137,0.00013664724,0.00027574904,0.00012225256,0.0003213394,0.0002745112,0.00027287588],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012215377,0.000022322827,0.0119612785,0.00015106145,0.000076371776,0.009016367,0.00007351441,0.00021241368,0.9667732,0.00032972003,0.0002784775,0.010983145],"study_design_scores_gemma":[0.00008303952,0.0003525982,0.14799999,0.0000640054,0.0003205053,0.101831555,0.00021208444,0.0029593382,0.72644204,0.00078373315,0.018901799,0.00004933046],"about_ca_topic_score_codex":0.00043832712,"about_ca_topic_score_gemma":0.0011513864,"teacher_disagreement_score":0.0007358459,"about_ca_system_score_codex":0.00013925525,"about_ca_system_score_gemma":0.00019712881,"threshold_uncertainty_score":0.0024616718},"labels":[],"label_agreement":null},{"id":"W2895375308","doi":"10.1172/jci93090","title":"Macrophage migration inhibitory factor mediates metabolic dysfunction induced by atypical antipsychotic therapy","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Shanghai Jiao Tong University; National Institutes of Health; National Science Foundation; Yale University; Memorial University of Newfoundland; National Natural Science Foundation of China","keywords":"Macrophage migration inhibitory factor; Antipsychotic; Inhibitory postsynaptic potential; Medicine; Schizophrenia (object-oriented programming); Macrophage; Atypical antipsychotic; Pharmacology; Immunology; Internal medicine; Biology; Psychiatry; Cytokine; Biochemistry; In vitro","score_opus":0.06459965164496478,"score_gpt":0.34237847757471856,"score_spread":0.2777788259297538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895375308","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966619,0.0019034507,0.0003352998,0.0001247092,0.000015160442,0.000014444551,0.000048581147,0.000015794822,0.0008806306],"genre_scores_gemma":[0.9988343,0.0007200129,0.00014749779,0.000042915588,0.000011203081,0.000013160773,0.00004111959,0.0000016106665,0.00018821516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999069,0.0000335515,0.0000059840004,0.0000067230085,0.000013986613,0.000032903936],"domain_scores_gemma":[0.99990726,0.000010921749,0.000048543996,0.000004644741,0.000007147304,0.000021517842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015414084,0.0003129316,0.00020719625,0.0001732647,0.00010657673,0.00018543586,0.000097137905,0.00021487114,0.0006499001],"category_scores_gemma":[0.00020979426,0.00008350934,0.00013953066,0.00009544121,0.00020961251,0.00009460252,0.00023644739,0.00038295524,0.000099497294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004836823,0.0002031803,0.029745387,0.00016461733,0.000032294985,0.0021123954,0.00011574888,0.00027352816,0.94713545,0.00044048653,0.00032423035,0.014615951],"study_design_scores_gemma":[0.0005585498,0.0051291054,0.66369206,0.00014401753,0.00018676146,0.0048050596,0.0007801252,0.0053498414,0.31084368,0.0015059428,0.0069638286,0.00004108102],"about_ca_topic_score_codex":0.00048461295,"about_ca_topic_score_gemma":0.00064328115,"teacher_disagreement_score":0.0006499001,"about_ca_system_score_codex":0.00027954148,"about_ca_system_score_gemma":0.00020060457,"threshold_uncertainty_score":0.002174139},"labels":[],"label_agreement":null},{"id":"W2898125316","doi":"10.1172/jci121303","title":"DNA hypermethylation within TERT promoter upregulates TERT expression in cancer","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":187,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; Princess Margaret Cancer Centre; Toronto Western Hospital; Hospital for Sick Children; University of British Columbia; McGill University; University of Calgary; Montreal Neurological Institute and Hospital; University Health Network; SickKids Foundation; University of Toronto","funders":"National Institute of General Medical Sciences; Fundação para a Ciência e a Tecnologia; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Centro de Investigação em Biomedicina","keywords":"DNA methylation; Telomerase; Telomere; Downregulation and upregulation; Cancer; Telomerase reverse transcriptase; Cancer research; CpG site; Methylation; Epigenetics; Biology; Molecular biology; Cancer cell; DNA; Gene expression; Gene; Genetics","score_opus":0.10296398178250638,"score_gpt":0.41082243855121925,"score_spread":0.3078584567687129,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898125316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944285,0.0031198855,0.0012720103,0.00005138271,0.000008812259,0.000016977621,0.00014384864,0.000037499405,0.0009211315],"genre_scores_gemma":[0.9977685,0.00096508296,0.0005566631,0.0000239162,0.0000057616,0.000007791,0.00014455096,0.000003023396,0.0005247918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999119,0.000020196103,0.000007507452,0.000024667406,0.000021999105,0.000013625507],"domain_scores_gemma":[0.99988115,0.000028899298,0.000041523566,0.000015424486,0.000017276352,0.000015761862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001745157,0.000087037966,0.00012791142,0.00031312677,0.00011143621,0.00016810463,0.000070570524,0.00013623456,0.0008710863],"category_scores_gemma":[0.0003455988,0.00009180889,0.00010906152,0.00022719691,0.00010762589,0.00008749065,0.00011434416,0.00017653932,0.0001460804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030338962,0.000031417872,0.032934073,0.000083204024,0.000030216146,0.000294048,0.00010780892,0.00020407444,0.94959766,0.00011032923,0.00010094097,0.016202848],"study_design_scores_gemma":[0.000025617188,0.0006672861,0.36550337,0.000025547803,0.00010845887,0.0034468246,0.00015596881,0.0015605922,0.6225634,0.00034745823,0.0055834,0.000012052768],"about_ca_topic_score_codex":0.00042626943,"about_ca_topic_score_gemma":0.0008700664,"teacher_disagreement_score":0.0008710863,"about_ca_system_score_codex":0.00014273041,"about_ca_system_score_gemma":0.00017384706,"threshold_uncertainty_score":0.002914071},"labels":[],"label_agreement":null},{"id":"W2898955021","doi":"10.1172/jci122064","title":"Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wuhan University; National Natural Science Foundation of China; Ministry of Science and Technology of the People's Republic of China; Chinese Academy of Sciences; University of Alberta; Georgia State University","keywords":"ALDH2; LDL receptor; Acetaldehyde; Chemistry; Cell biology; Biology; Aldehyde dehydrogenase; Biochemistry; Lipoprotein; Cholesterol; Enzyme; Ethanol","score_opus":0.19324731703546366,"score_gpt":0.4617449946419916,"score_spread":0.26849767760652793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898955021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871891,0.005209736,0.004187103,0.00036630104,0.00010445404,0.000022937105,0.00021455645,0.00014389427,0.0025618093],"genre_scores_gemma":[0.9954223,0.0008530133,0.0011023689,0.000118531585,0.000029492665,0.000029498628,0.0001708552,0.000016454496,0.0022573338],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997899,0.000038824157,0.000014378591,0.000047230595,0.000052366926,0.000057265555],"domain_scores_gemma":[0.9999192,0.0000074561335,0.000028820137,0.000006618279,0.00001199758,0.000025804953],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014704959,0.00026316807,0.000239983,0.00016605684,0.00017900544,0.00029403227,0.00012987804,0.00024548813,0.0013278775],"category_scores_gemma":[0.00010893462,0.00017571995,0.0003101814,0.00009560062,0.00020768735,0.00013800462,0.00024194685,0.00030910215,0.00040370048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030671895,0.000036955,0.0013419995,0.000057009143,0.00001896927,0.00016744928,0.00003854023,0.000058160887,0.99575186,0.0002271419,0.00017628814,0.0018188778],"study_design_scores_gemma":[0.00010925502,0.00037955565,0.06147642,0.000018994984,0.00008576849,0.00082877045,0.00021913243,0.0030199208,0.9247293,0.0005190351,0.008589505,0.000024411172],"about_ca_topic_score_codex":0.00038459225,"about_ca_topic_score_gemma":0.00047239108,"teacher_disagreement_score":0.0013278775,"about_ca_system_score_codex":0.0002201271,"about_ca_system_score_gemma":0.00012137985,"threshold_uncertainty_score":0.0044421554},"labels":[],"label_agreement":null},{"id":"W2899632244","doi":"10.1172/jci96098","title":"Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel–associated retinopathy","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Eye Institute; Eberhard Karls Universität Tübingen; Deutsche Forschungsgemeinschaft; ERAB: The European Foundation for Alcohol Research; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research","keywords":"Achromatopsia; Genetics; Retinal Disorder; Mutation; Allele; Phenotype; Biology; Retinal; Gene","score_opus":0.05385788611792888,"score_gpt":0.3537389774303939,"score_spread":0.299881091312465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899632244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99712676,0.00028781415,0.00068405515,0.000089671965,0.000025097193,0.000037701873,0.00021097898,0.00017644673,0.0013614418],"genre_scores_gemma":[0.99734604,0.0002241733,0.0007107255,0.00011676467,0.000021478429,0.000022463222,0.00019902481,0.000067227884,0.0012920648],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99954706,0.00007519375,0.00004053908,0.000110011206,0.00012416142,0.000102985076],"domain_scores_gemma":[0.9995246,0.00006552341,0.00016771624,0.000040736082,0.000027050584,0.00017431549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031573657,0.0014086195,0.000689039,0.00089040824,0.00046042746,0.0003325193,0.000341833,0.00085212686,0.0035580364],"category_scores_gemma":[0.00040673124,0.00037406225,0.00058418344,0.00043712292,0.0005896442,0.00022086123,0.00080761244,0.0009400553,0.0005213003],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007812438,0.00029585554,0.0060872342,0.00006327836,0.0000576873,0.009085185,0.00012188189,0.00026435475,0.9799774,0.0002348459,0.00037557734,0.002655484],"study_design_scores_gemma":[0.0008918015,0.0044936826,0.5132238,0.000107689884,0.00071371853,0.14158525,0.00079993496,0.0086377375,0.31928617,0.0015215072,0.0085770385,0.00016163531],"about_ca_topic_score_codex":0.0022274114,"about_ca_topic_score_gemma":0.0036131607,"teacher_disagreement_score":0.0035580364,"about_ca_system_score_codex":0.00034460804,"about_ca_system_score_gemma":0.00038274843,"threshold_uncertainty_score":0.011902809},"labels":[],"label_agreement":null},{"id":"W2900926271","doi":"10.1172/jci124011","title":"Rescue of recurrent deep intronic mutation underlying cell type–dependent quantitative NEMO deficiency","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"NIHR Newcastle Biomedical Research Centre; Japan Society for the Promotion of Science; National Institutes of Health; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de Sécurité du Médicament et des Produits de Santé; Japan Agency for Medical Research and Development; Newcastle University; Hospital for Sick Children; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Université Paris Descartes; Research Center Network for Realization of Regenerative Medicine; National Institute for Health and Care Research; St. Giles Foundation; Agence Nationale de la Recherche","keywords":"Mutation; Genetics; Biology; Computational biology; Gene","score_opus":0.09378151201178306,"score_gpt":0.3848726889200379,"score_spread":0.2910911769082548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900926271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953713,0.00029753413,0.0029119414,0.000046271573,0.000023950586,0.000022796647,0.000260146,0.000119459786,0.00094662205],"genre_scores_gemma":[0.9944543,0.00035860538,0.0018392089,0.000028647108,0.000005760958,0.000020352156,0.0004996114,0.000055779725,0.002737665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998877,0.000016682236,0.000020243802,0.000023329512,0.0000326022,0.000019392837],"domain_scores_gemma":[0.99987185,0.00001693658,0.000035202313,0.000023653398,0.0000078204275,0.00004456674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011526978,0.00041548745,0.0002687971,0.00015360634,0.00012104212,0.00014705662,0.0002382844,0.00031311094,0.0010988875],"category_scores_gemma":[0.00009776797,0.00013376497,0.00023555094,0.00006751462,0.0002036187,0.000092144284,0.00039952016,0.0004006493,0.000496434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017851446,0.0000075932853,0.00009891029,0.000013225066,0.000002620378,0.00022173866,0.000009221707,0.000029953195,0.9991611,0.000042774253,0.000009744821,0.00038513885],"study_design_scores_gemma":[0.000023993902,0.00025329817,0.006298296,0.00000985247,0.000021019783,0.0027674527,0.00006311226,0.0010423907,0.9853698,0.00007151276,0.004071009,0.000008207174],"about_ca_topic_score_codex":0.00032245187,"about_ca_topic_score_gemma":0.00057605444,"teacher_disagreement_score":0.0010988875,"about_ca_system_score_codex":0.000086812586,"about_ca_system_score_gemma":0.00014622339,"threshold_uncertainty_score":0.003676176},"labels":[],"label_agreement":null},{"id":"W2901208879","doi":"10.1172/jci121004","title":"Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario; Ottawa Hospital; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute; Ontario Institute for Cancer Research","keywords":"Immunotherapy; Oncolytic virus; Immunology; Medicine; Melanoma; Cancer immunotherapy; Immunosuppression; Blockade; Tumor microenvironment; Antigen; Cancer research; Immune system; Receptor; Internal medicine","score_opus":0.08244466000754858,"score_gpt":0.40139462229742134,"score_spread":0.31894996228987277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901208879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921112,0.0013032753,0.003739991,0.00011143525,0.000067705536,0.000052688705,0.00010161575,0.00013127112,0.002380863],"genre_scores_gemma":[0.9964521,0.0005955016,0.0015117574,0.000056734116,0.00002797713,0.000043988395,0.00008458068,0.000020696,0.0012066656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998628,0.000029474983,0.000015388705,0.000018301398,0.000033735047,0.00004036467],"domain_scores_gemma":[0.9998982,0.000023083194,0.00002657498,0.00001829908,0.000008088216,0.000025778045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016365919,0.0003754581,0.0003774085,0.00022650542,0.00010701361,0.00029994446,0.00015865498,0.00021191647,0.0008778957],"category_scores_gemma":[0.00011060537,0.00008900705,0.00017024552,0.00011117459,0.00024087864,0.00019340505,0.00016116639,0.00097115646,0.00019350686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035300676,0.00015956399,0.00028158072,0.0000465495,0.000007202179,0.000056984383,0.000012575529,0.00023928506,0.99180025,0.00030233152,0.00005712204,0.0066835317],"study_design_scores_gemma":[0.000097586446,0.002110909,0.0018376819,0.000010747462,0.00002162653,0.00031370044,0.000014868885,0.0012749983,0.99197656,0.00019856571,0.0021394754,0.0000033942592],"about_ca_topic_score_codex":0.00013433352,"about_ca_topic_score_gemma":0.00037413914,"teacher_disagreement_score":0.0008778957,"about_ca_system_score_codex":0.00016327092,"about_ca_system_score_gemma":0.00029544346,"threshold_uncertainty_score":0.00293684},"labels":[],"label_agreement":null},{"id":"W2901444941","doi":"10.1172/jci125264","title":"Blocking HIV-1 replication: are Fc–Fcγ receptor interactions required?","year":2018,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Receptor; Viral replication; Blocking (statistics); Simian immunodeficiency virus; In vivo; Virology; Human immunodeficiency virus (HIV); Replication (statistics); Immunology; Fc receptor; Biology; Virus; Antibody; Computer science; Genetics","score_opus":0.21884101574675813,"score_gpt":0.4629779895469273,"score_spread":0.2441369738001692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901444941","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015104567,0.01925463,0.00079829,0.94424355,0.008831964,0.000041997882,0.00004615394,0.000058756235,0.011620075],"genre_scores_gemma":[0.23660362,0.03700203,0.0023592033,0.619661,0.08412146,0.00011833615,0.000097299366,0.000048330578,0.019988844],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992065,0.0003026743,0.00007956724,0.00007042145,0.0002056826,0.00013522213],"domain_scores_gemma":[0.9983991,0.0010289231,0.00013720774,0.00007989095,0.00022237036,0.00013258561],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012785004,0.0003469351,0.00081003254,0.00019884783,0.0007620415,0.0012099814,0.0007964434,0.01473485,0.003954457],"category_scores_gemma":[0.0049840147,0.00021058427,0.00037642109,0.00018443445,0.0014109933,0.0018127995,0.00031352497,0.008011994,0.0025401602],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011675742,0.00052514893,0.010823978,0.0006087286,0.00007384843,0.0625752,0.0007552447,0.00028818956,0.02348433,0.023204518,0.63288087,0.24361241],"study_design_scores_gemma":[0.00070556445,0.0013906612,0.008018565,0.00054308225,0.00011242032,0.07772033,0.0014684212,0.0019276077,0.011076448,0.02866769,0.8682947,0.00007464394],"about_ca_topic_score_codex":0.0005924216,"about_ca_topic_score_gemma":0.0007602514,"teacher_disagreement_score":0.01473485,"about_ca_system_score_codex":0.0015351248,"about_ca_system_score_gemma":0.0004998742,"threshold_uncertainty_score":0.0132290125},"labels":[],"label_agreement":null},{"id":"W2901685517","doi":"10.1172/jci122466","title":"Fc-dependent functions are redundant to efficacy of anti-HIV antibody PGT121 in macaques","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Infection and Immunity; National Health and Medical Research Council; Medical Research Council; University of Melbourne; Australian Centre for HIV and Hepatitis Virology Research","keywords":"Viremia; Simian immunodeficiency virus; Macaque; Antibody; Rhesus macaque; Virology; Immunology; Biology; Neutralizing antibody; Human immunodeficiency virus (HIV); Virus; AIDS Vaccines; Neuroscience; Vaccine trial","score_opus":0.08087076611623029,"score_gpt":0.41681369097564047,"score_spread":0.3359429248594102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901685517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99816656,0.000783361,0.00031761132,0.00006772029,0.000009159685,0.00001655741,0.00007555631,0.000022812186,0.0005406771],"genre_scores_gemma":[0.9981895,0.00036012125,0.0004453531,0.00007591347,0.000013378787,0.000026632282,0.00018520259,0.000008152016,0.00069572555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999723,0.00005612356,0.000019790521,0.00005536464,0.00005861372,0.00008706218],"domain_scores_gemma":[0.999739,0.000072492876,0.000057505513,0.000041493284,0.00003144063,0.0000579766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029480195,0.0003283585,0.00036725347,0.000295317,0.0002182173,0.000425679,0.00033695137,0.0006318902,0.0010630753],"category_scores_gemma":[0.00043986097,0.00014380897,0.00022591875,0.00007424781,0.00049002736,0.00045602935,0.00022951436,0.00087417196,0.00021844357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008089517,0.00012370422,0.001160458,0.00006467519,0.0000114000095,0.00015746415,0.00008334363,0.000073952586,0.993838,0.00015381063,0.00007163836,0.0034526957],"study_design_scores_gemma":[0.0001229879,0.007667149,0.031486496,0.000038019625,0.0001162644,0.0029745707,0.00018503089,0.0020503488,0.94994026,0.00028780597,0.0051117516,0.00001933686],"about_ca_topic_score_codex":0.0013504609,"about_ca_topic_score_gemma":0.0012612141,"teacher_disagreement_score":0.0013504609,"about_ca_system_score_codex":0.000374794,"about_ca_system_score_gemma":0.0002657297,"threshold_uncertainty_score":0.0035563707},"labels":[],"label_agreement":null},{"id":"W2902019463","doi":"10.1172/jci124473","title":"Live attenuated varicella-zoster virus vaccine does not induce HIV target cell activation","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba; St. Michael's Hospital; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Sanofi Pasteur; King's College London; Pfizer; Ontario HIV Treatment Network; University of Manitoba; Sanofi; University of Toronto; GlaxoSmithKline","keywords":"Vaccination; Immunology; Varicella zoster virus; Medicine; Virology; Immune system; Virus","score_opus":0.07022546011626699,"score_gpt":0.3714066756111072,"score_spread":0.3011812154948402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902019463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99793386,0.0008185033,0.00043700205,0.000020343978,0.000012353658,0.000044368047,0.00008212615,0.0000099248155,0.0006414069],"genre_scores_gemma":[0.9985423,0.00023954395,0.0003332949,0.000017850774,0.0000065919303,0.000039249255,0.00016984995,0.0000027220306,0.0006486237],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998254,0.00004003687,0.000010993101,0.00002672678,0.000058760328,0.000038070957],"domain_scores_gemma":[0.9998165,0.000070586175,0.00004247335,0.000029474406,0.000021717027,0.000019339983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020450262,0.00016077775,0.00031611306,0.000083677696,0.000062747225,0.00018094493,0.00013697417,0.00021794927,0.00196536],"category_scores_gemma":[0.00032995132,0.00006399248,0.00009043144,0.00007637241,0.00018443445,0.0001656504,0.000119496326,0.00035955833,0.00019267946],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020724453,0.000586047,0.00980366,0.00037342298,0.00004858925,0.00011093027,0.000083081344,0.00017386743,0.97108895,0.00016344288,0.00015369523,0.015341745],"study_design_scores_gemma":[0.0005230776,0.050105833,0.16907921,0.00009915241,0.00016395276,0.002547817,0.00028317855,0.0021206364,0.7647219,0.00034393792,0.009999967,0.000011483714],"about_ca_topic_score_codex":0.00020161262,"about_ca_topic_score_gemma":0.00029470047,"teacher_disagreement_score":0.00196536,"about_ca_system_score_codex":0.00016881526,"about_ca_system_score_gemma":0.00015161769,"threshold_uncertainty_score":0.0065748096},"labels":[],"label_agreement":null},{"id":"W2902472115","doi":"10.1172/jci123366","title":"Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Infection and Immunity; National Health and Medical Research Council; Medical Research Council; Australian Government","keywords":"Biology; Immunogenicity; Hemagglutinin (influenza); Stem cell; Immunology; Virology; Vaccination; Immunity; Epitope; Immune system; Antibody; Antigen; Influenza vaccine; Cell biology","score_opus":0.23944098935478897,"score_gpt":0.4575142499984245,"score_spread":0.21807326064363552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902472115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99365026,0.0018263764,0.003050364,0.00007302037,0.000008020992,0.000023825596,0.00003052203,0.000035273384,0.0013023354],"genre_scores_gemma":[0.997712,0.0005129669,0.0013053992,0.00006988924,0.0000120241875,0.000012409106,0.00003864008,0.0000064668466,0.00033029265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998702,0.000040883024,0.000008155235,0.000016169357,0.000030909458,0.000033819473],"domain_scores_gemma":[0.99981266,0.000074831165,0.000039056737,0.000016927212,0.00002386011,0.000032634434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002825543,0.00021634428,0.00018613682,0.00013209789,0.00009129207,0.00038737344,0.00014947836,0.00024173518,0.000908282],"category_scores_gemma":[0.00027531193,0.00012823983,0.00012957472,0.000049928665,0.00023957492,0.00035444784,0.00021913886,0.0004427548,0.0003340263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007911235,0.000022247814,0.0017766844,0.000042021904,0.0000036134415,0.000028898285,0.000020668733,0.00008729715,0.99437743,0.00015420056,0.000027664099,0.003380183],"study_design_scores_gemma":[0.000034950892,0.0023819397,0.030529428,0.000029271323,0.000035939604,0.0011881172,0.00023411463,0.002511378,0.95759755,0.0007315054,0.0047198446,0.0000060658667],"about_ca_topic_score_codex":0.0001817365,"about_ca_topic_score_gemma":0.000308563,"teacher_disagreement_score":0.000908282,"about_ca_system_score_codex":0.00012907898,"about_ca_system_score_gemma":0.00015177173,"threshold_uncertainty_score":0.0030385256},"labels":[],"label_agreement":null},{"id":"W2903326024","doi":"10.1172/jci122595","title":"Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Chylomicron; Phosphatidic acid; Biochemistry; Phospholipid; Enterocyte; Biology; Phosphatidylethanolamine; Cell biology; Chemistry; Lipoprotein; Very low-density lipoprotein; Phosphatidylcholine; Cholesterol; Small intestine; Membrane","score_opus":0.03310942295819737,"score_gpt":0.32846690266350415,"score_spread":0.2953574797053068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903326024","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9767421,0.0070332093,0.010988808,0.0003481859,0.00010452162,0.00006175645,0.00081380835,0.0003627846,0.0035448414],"genre_scores_gemma":[0.9893707,0.0018783201,0.0035616828,0.00011701497,0.000021657444,0.000051898245,0.0005666423,0.000054850036,0.00437714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998722,0.00001365818,0.000010799873,0.00003604692,0.000029608125,0.00003763176],"domain_scores_gemma":[0.9999114,0.000006079845,0.000023371464,0.000012848956,0.000015503825,0.00003072549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016368025,0.00036180697,0.00024113554,0.00026687325,0.0002516324,0.00061596534,0.00024084028,0.00031497623,0.0008454484],"category_scores_gemma":[0.0001331733,0.00015931002,0.00026036435,0.00016776356,0.00030954037,0.00035743086,0.0004016644,0.0004811869,0.00045464362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014395757,0.0000070392175,0.00030370412,0.000024960813,0.0000033821339,0.000052428473,0.0000103011,0.000047790687,0.9981633,0.00020676956,0.000049341503,0.0009870484],"study_design_scores_gemma":[0.000032015807,0.00008310971,0.008638855,0.000009972362,0.00001860751,0.000284044,0.00004860088,0.0010924259,0.9837256,0.00025586731,0.005802627,0.000008186566],"about_ca_topic_score_codex":0.0007729263,"about_ca_topic_score_gemma":0.0011752532,"teacher_disagreement_score":0.0008454484,"about_ca_system_score_codex":0.0005496227,"about_ca_system_score_gemma":0.00042764307,"threshold_uncertainty_score":0.0039878488},"labels":[],"label_agreement":null},{"id":"W2909310706","doi":"10.1172/jci123959","title":"Loss of the sphingolipid desaturase DEGS1 causes hypomyelinating leukodystrophy","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster Children's Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Human Genome Research Institute; European Regional Development Fund; Agència de Gestió d'Ajuts Universitaris i de Recerca; Canadian Institutes of Health Research; U.S. Navy; Intellectual and Developmental Disabilities Research Center; National Institutes of Health; Université Paris Diderot; Ministerio de Economía y Competitividad; Fondation pour la Recherche Médicale; Generalitat de Catalunya; Baylor-Hopkins Center for Mendelian Genomics; Agence Nationale de la Recherche; Instituto de Salud Carlos III; National Research Foundation; National Multiple Sclerosis Society; Fundación Hesperia; Center for Individualized Medicine, Mayo Clinic; Centres de Recerca de Catalunya; Ontario Genomics Institute; Howard Hughes Medical Institute; Georgia Clinical and Translational Science Alliance; Simons Foundation Autism Research Initiative; Génome Québec; Mayo Clinic; National Ataxia Foundation; Ontario Genomics; U.S. Department of Defense; Simons Foundation; Genome Canada; Yale University; Institut National de la Santé et de la Recherche Médicale; Johns Hopkins University; McGill University; European Commission; Broad Institute","keywords":"Sphingolipid; Leukodystrophy; Myelin; Fingolimod; Biology; Spasticity; Endoplasmic reticulum; Zebrafish; Neuroscience; Ceramide; Cell biology; Medicine; Internal medicine; Genetics; Multiple sclerosis; Immunology; Disease; Gene; Physical medicine and rehabilitation; Central nervous system","score_opus":0.03387428700805739,"score_gpt":0.32016787420756126,"score_spread":0.2862935871995039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2909310706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99469084,0.00150845,0.0018927484,0.00026534242,0.00003497765,0.000036017336,0.0007757922,0.00013985657,0.0006559983],"genre_scores_gemma":[0.9952467,0.0012122636,0.0016981134,0.0001522844,0.000016169186,0.000023078652,0.000650617,0.000015963127,0.000984863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999877,0.000017743618,0.000017933933,0.000042736454,0.00002343677,0.000021142021],"domain_scores_gemma":[0.99992883,0.0000155508,0.000024799301,0.0000066949524,0.0000057568536,0.000018421228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016112598,0.00060713745,0.00030259322,0.00045323838,0.00018989913,0.00018338564,0.0001545211,0.0005014916,0.0009398534],"category_scores_gemma":[0.0001486419,0.00020588841,0.00022314343,0.00022666507,0.00035706238,0.00011010091,0.0001975358,0.0004971545,0.00023286416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071794994,0.000090112306,0.0038078541,0.000112076326,0.000039110066,0.0029613345,0.00004128334,0.00017177624,0.98433244,0.00015243105,0.00033443174,0.0072393324],"study_design_scores_gemma":[0.00029365157,0.0016825299,0.12368164,0.000060747254,0.00037725375,0.036515545,0.00017165748,0.0034141566,0.8218383,0.0004662829,0.011461515,0.000036701145],"about_ca_topic_score_codex":0.00046376674,"about_ca_topic_score_gemma":0.00070713373,"teacher_disagreement_score":0.0009398534,"about_ca_system_score_codex":0.00025835005,"about_ca_system_score_gemma":0.00018724582,"threshold_uncertainty_score":0.0031440854},"labels":[],"label_agreement":null},{"id":"W2909352392","doi":"10.1172/jci123267","title":"Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; Medical Research Council; Canadian Institutes of Health Research; University of California, San Diego; National Institutes of Health; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Narodowe Centrum Nauki; Rheumatology Research Foundation","keywords":"Autoimmunity; FOXP3; Immunology; Biology; Peripheral tolerance; Autoimmune disease; Cancer research; Immune system; Antibody","score_opus":0.03449056412691465,"score_gpt":0.32930145011024164,"score_spread":0.294810885983327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2909352392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970968,0.0009025787,0.0010502624,0.000057347297,0.000018092927,0.00001057105,0.00007867129,0.000056011206,0.00072965777],"genre_scores_gemma":[0.998468,0.00029181523,0.00043976872,0.000021189422,0.0000071037025,0.0000113077085,0.0000793729,0.000008587985,0.00067278673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981195,0.000042578846,0.000017928525,0.00003541557,0.000049115893,0.00004310352],"domain_scores_gemma":[0.99987376,0.000019686593,0.00003285973,0.000016679027,0.000008036304,0.000048920574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002145123,0.00029741495,0.00028245224,0.00025988446,0.000115130926,0.0002773471,0.00012834441,0.00027118978,0.00089346565],"category_scores_gemma":[0.00015576922,0.00015432335,0.00017732177,0.00011490412,0.00031349447,0.00016501037,0.00020029879,0.00073872734,0.0002119207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018514822,0.0000544151,0.00031593896,0.000016080057,0.000003876096,0.00006507588,0.000007604423,0.000060206643,0.9986066,0.00006930595,0.000021369255,0.0005943773],"study_design_scores_gemma":[0.00008161661,0.0012864443,0.009891917,0.000008834875,0.000031494164,0.0010289444,0.000031684438,0.0015509786,0.9841127,0.00014311161,0.0018265882,0.000005663921],"about_ca_topic_score_codex":0.0003241508,"about_ca_topic_score_gemma":0.00058577745,"teacher_disagreement_score":0.00089346565,"about_ca_system_score_codex":0.00021350408,"about_ca_system_score_gemma":0.00015964029,"threshold_uncertainty_score":0.0029889941},"labels":[],"label_agreement":null},{"id":"W2911163118","doi":"10.1172/jci122622","title":"Inhibiting Wee1 and ATR kinases produces tumor-selective synthetic lethality and suppresses metastasis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta; Alberta Cancer Foundation; Canadian Institutes of Health Research; Cancer Research Society; AstraZeneca","keywords":"Wee1; Synthetic lethality; Cancer research; Cancer cell; Cancer; DNA damage; Kinase; Mitosis; Metastasis; Biology; Cell cycle; DNA repair; Chemistry; Cell biology; Cyclin-dependent kinase 1; DNA; Biochemistry; Genetics","score_opus":0.03591855522157875,"score_gpt":0.3291808137633033,"score_spread":0.29326225854172455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911163118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98630977,0.0024470205,0.0077563724,0.00017930155,0.000047704638,0.0000981349,0.0004708553,0.00022860285,0.0024622],"genre_scores_gemma":[0.99227434,0.001025717,0.0038778256,0.00003967573,0.000014115834,0.00006126157,0.00046044873,0.00003499131,0.002211807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997768,0.000037091817,0.000021830017,0.000043797132,0.00006904615,0.000051510833],"domain_scores_gemma":[0.99986863,0.000023743385,0.000032595235,0.00002013373,0.000009615709,0.000045293724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032326076,0.0005248617,0.0004325181,0.00045379633,0.00012749412,0.0002776032,0.00024257698,0.00024721544,0.001354401],"category_scores_gemma":[0.00013805385,0.00020281768,0.00029268308,0.00018715853,0.00023958838,0.0002253826,0.00028200637,0.00068721885,0.00029435597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013949416,0.00008081353,0.00013190655,0.000032851927,0.0000110189485,0.000043490363,0.000008107556,0.00018561984,0.996194,0.00020576913,0.000050654307,0.0029161498],"study_design_scores_gemma":[0.000046138666,0.0013873227,0.0010670855,0.0000032746761,0.000021161122,0.0002487261,0.000007963495,0.0010917243,0.9934962,0.000052584135,0.0025743938,0.0000033037952],"about_ca_topic_score_codex":0.00025418014,"about_ca_topic_score_gemma":0.0007583726,"teacher_disagreement_score":0.001354401,"about_ca_system_score_codex":0.00016731785,"about_ca_system_score_gemma":0.00030985542,"threshold_uncertainty_score":0.0045309067},"labels":[],"label_agreement":null},{"id":"W2912325278","doi":"10.1172/jci123931","title":"Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Johns Hopkins University; Canadian Institutes of Health Research; Faculté de Médecine, Université Laval; Université Laval","keywords":"Neuroinflammation; Amyotrophic lateral sclerosis; Neuropathology; Antibody; Frontotemporal dementia; Biology; Transgene; Virology; Cancer research; Immunology; Medicine; Dementia; Gene; Pathology; Inflammation; Genetics; Disease","score_opus":0.06360490847107622,"score_gpt":0.377783688119841,"score_spread":0.3141787796487647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912325278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99536693,0.0010640679,0.0020942036,0.00012509152,0.000099967896,0.000054744047,0.000108166656,0.00012744528,0.0009594036],"genre_scores_gemma":[0.9946689,0.00071496516,0.0020495616,0.00005781613,0.000026663974,0.00003881521,0.0002073728,0.0000189324,0.0022169617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998468,0.000020487862,0.000012499805,0.000028784543,0.000032263026,0.00005908898],"domain_scores_gemma":[0.99993455,0.000008294084,0.00001615657,0.0000054445777,0.000010954322,0.000024541958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001788727,0.00038541417,0.0005069731,0.00028396837,0.00018093784,0.00034449765,0.00024187281,0.0005816502,0.00076263834],"category_scores_gemma":[0.00011184564,0.00013296571,0.00021161522,0.00012442892,0.00024069793,0.0003140461,0.00015704808,0.0007816286,0.00019502836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035473896,0.0002504349,0.00006143389,0.00005130905,0.000012301013,0.00004223873,0.000022522037,0.00012259035,0.9959335,0.0001420964,0.000080291364,0.0029265368],"study_design_scores_gemma":[0.00021660184,0.0059994203,0.0026251639,0.000016767417,0.00008653244,0.00030676133,0.000047532852,0.002854528,0.98456764,0.00012889509,0.0031396456,0.00001055849],"about_ca_topic_score_codex":0.0010837091,"about_ca_topic_score_gemma":0.0014473522,"teacher_disagreement_score":0.0010837091,"about_ca_system_score_codex":0.00025783747,"about_ca_system_score_gemma":0.00036268117,"threshold_uncertainty_score":0.0025513172},"labels":[],"label_agreement":null},{"id":"W2912925337","doi":"10.1172/jci125980","title":"Ulk1/Rab9-mediated alternative mitophagy confers cardioprotection during energy stress","year":2019,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Cardioprotection; ULK1; Stress (linguistics); Autophagy; Medicine; Biology; Cell biology; Internal medicine; Ischemia; Biochemistry; Kinase","score_opus":0.05551144062152267,"score_gpt":0.3493674525936576,"score_spread":0.2938560119721349,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912925337","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.053864405,0.0061560785,0.0012503725,0.866759,0.032446653,0.00010379049,0.00016497647,0.00047904757,0.038775705],"genre_scores_gemma":[0.36052838,0.007860835,0.0016786045,0.5000975,0.074808694,0.0001558984,0.00017333638,0.00009739985,0.05459939],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996076,0.00012671991,0.00003683521,0.000045115947,0.00008494244,0.00009876188],"domain_scores_gemma":[0.99884534,0.0006344089,0.00008181247,0.00008642388,0.00020136895,0.00015061628],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005874307,0.00042027025,0.0006959583,0.00029974035,0.0009831013,0.0009782298,0.00045845774,0.007833039,0.002562591],"category_scores_gemma":[0.0033977795,0.00020379155,0.0004220023,0.00023450401,0.0009937235,0.00074439636,0.00030358435,0.0053921477,0.0026744925],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012612777,0.00040251986,0.007671709,0.00026118307,0.00006672852,0.19760932,0.0004812733,0.00037268118,0.014053108,0.0076943096,0.7098326,0.06029325],"study_design_scores_gemma":[0.001105466,0.0011611289,0.019470481,0.00035008392,0.00013924525,0.19529232,0.00083633495,0.0068574743,0.015398161,0.019447835,0.7397977,0.00014373787],"about_ca_topic_score_codex":0.0006694503,"about_ca_topic_score_gemma":0.0010460683,"teacher_disagreement_score":0.007833039,"about_ca_system_score_codex":0.0013424098,"about_ca_system_score_gemma":0.00045943397,"threshold_uncertainty_score":0.009739935},"labels":[],"label_agreement":null},{"id":"W2913110287","doi":"10.1172/jci124516","title":"Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":168,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Wellcome Trust; Wellcome","keywords":"Cryptococcal meningitis; Fluconazole; Cryptococcosis; Meningitis; Cryptococcus neoformans; Resistance (ecology); Ploidy; Microbiology; Medicine; Immunology; Biology; Antifungal; Human immunodeficiency virus (HIV); Genetics; Surgery; Viral disease; Ecology; Gene","score_opus":0.05292326369605098,"score_gpt":0.38591546201775956,"score_spread":0.33299219832170857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913110287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998713,0.0005759648,0.00010668292,0.000017887876,0.0000010264351,0.000013000397,0.00030658577,0.00000812998,0.0002577288],"genre_scores_gemma":[0.999169,0.0002444897,0.000116467825,0.000015686805,0.0000024956992,0.000010763826,0.00030077968,0.000002232371,0.00013819992],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998939,0.0000132040295,0.000008733633,0.000030060242,0.000025470614,0.000028572564],"domain_scores_gemma":[0.9996538,0.0000595063,0.00018652742,0.000023731223,0.000044559823,0.000031913452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014415989,0.00016827206,0.0001975209,0.0007241057,0.0002369247,0.0003638895,0.00011989557,0.00027115797,0.0016175321],"category_scores_gemma":[0.00069906533,0.00015268082,0.000083627114,0.00060821447,0.00023161243,0.0001838126,0.0002531199,0.00017484049,0.00023818127],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00177062,0.00007831737,0.7061836,0.000107234955,0.000033085875,0.0010950948,0.00076580554,0.000624212,0.26739,0.000099417215,0.00039728635,0.021455389],"study_design_scores_gemma":[0.00001336932,0.00033620902,0.98529065,0.000014691674,0.000016161273,0.0020484587,0.00020097701,0.0003630159,0.010841907,0.0000759848,0.00079093303,0.0000075500575],"about_ca_topic_score_codex":0.002225317,"about_ca_topic_score_gemma":0.0018873222,"teacher_disagreement_score":0.002225317,"about_ca_system_score_codex":0.00038827665,"about_ca_system_score_gemma":0.00017979385,"threshold_uncertainty_score":0.005411148},"labels":[],"label_agreement":null},{"id":"W2913288555","doi":"10.1172/jci120412","title":"Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":127,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad","keywords":"Neurogenesis; Hippocampal formation; Neuroscience; Stroke (engine); Hippocampus; Forgetting; Psychology; Memory impairment; Memantine; Neural stem cell; Cognition; Doublecortin; Medicine; Dentate gyrus; Dementia; Internal medicine; Biology; Disease; Stem cell; Cognitive psychology","score_opus":0.06731522080757667,"score_gpt":0.341246545330423,"score_spread":0.2739313245228463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913288555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98822767,0.0024242282,0.0046517025,0.0003314521,0.00014137222,0.00011699341,0.00164347,0.0004924,0.0019706807],"genre_scores_gemma":[0.9767397,0.0039522694,0.005402918,0.00027226235,0.00004801868,0.00037697822,0.002010981,0.00013217377,0.01106469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997371,0.000025386114,0.000042003536,0.00006184675,0.00005354167,0.00008024925],"domain_scores_gemma":[0.999757,0.000013561797,0.00008324548,0.000031142063,0.000021185439,0.00009396155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031951568,0.0008396371,0.00076313486,0.0011205742,0.0002668847,0.00045102483,0.00056185777,0.0006656633,0.0017487835],"category_scores_gemma":[0.00012853916,0.00035824347,0.000542248,0.00033124516,0.00058591703,0.00039402305,0.00040237032,0.0016904306,0.00058254844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007596696,0.00047029668,0.0002713155,0.00011615918,0.000028611366,0.00012865868,0.000071781295,0.00013396067,0.9932961,0.00031207624,0.000154309,0.004256953],"study_design_scores_gemma":[0.00021803641,0.0038798084,0.008137101,0.00008096064,0.00010462229,0.0003442329,0.00011700894,0.0018785152,0.979654,0.0005335831,0.0050291284,0.00002291672],"about_ca_topic_score_codex":0.0010423403,"about_ca_topic_score_gemma":0.0019732108,"teacher_disagreement_score":0.0017487835,"about_ca_system_score_codex":0.00034473205,"about_ca_system_score_gemma":0.00050394214,"threshold_uncertainty_score":0.005850196},"labels":[],"label_agreement":null},{"id":"W2914282788","doi":"10.1172/jci96313","title":"Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":427,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research; Ontario Institute for Cancer Research; McGill University Health Centre; Montreal Neurological Institute and Hospital; University of Toronto; Centre Hospitalier de l’Université de Montréal; McGill University; Princess Margaret Cancer Centre; Occupational Cancer Research Centre","funders":"Merck Sharp and Dohme; National Cancer Institute; National Institutes of Health; University of Toronto; Québec Consortium for Drug Discovery; Ohio State University; McGill University Health Centre; Stand Up To Cancer; Faculty of Medicine, McGill University; McGill University; Deutsches Krebsforschungszentrum","keywords":"Stromal cell; Tumor microenvironment; Granzyme B; Triple-negative breast cancer; Immune system; Cancer research; CD8; Cytotoxic T cell; Biology; Granzyme; Laser capture microdissection; Immune checkpoint; Immunology; Breast cancer; Immunotherapy; Cancer; Gene expression; Perforin","score_opus":0.03719470121437023,"score_gpt":0.3412165992050687,"score_spread":0.30402189799069845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914282788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979079,0.0005230747,0.000808972,0.000025514648,0.000003415502,0.000011492108,0.00011493364,0.000017795845,0.00058682234],"genre_scores_gemma":[0.99913317,0.000108756154,0.0004441783,0.00001871477,0.000004121327,0.000007968347,0.00009362759,0.0000026035657,0.00018689987],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99991584,0.000015116291,0.000006083201,0.000019893463,0.000019367619,0.000023777682],"domain_scores_gemma":[0.99990475,0.000014430222,0.000042246098,0.000007675448,0.000010981033,0.000020018068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012924722,0.0001299131,0.00015775168,0.00057880406,0.00013396014,0.00040113655,0.000075130476,0.00016713941,0.000506388],"category_scores_gemma":[0.00017948383,0.000090580485,0.00010136425,0.00020301598,0.00017256118,0.00012801563,0.0002255333,0.00019586715,0.00010829589],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010517932,0.000048700585,0.20479682,0.00006906412,0.000044881646,0.00041195078,0.00026775835,0.00077103404,0.77774733,0.000406056,0.00020330574,0.014181251],"study_design_scores_gemma":[0.00002587393,0.00031580054,0.89145166,0.000021677482,0.00007947083,0.002363754,0.000805604,0.0038854338,0.09783892,0.00072313735,0.0024629063,0.000025797966],"about_ca_topic_score_codex":0.00080438406,"about_ca_topic_score_gemma":0.0017881528,"teacher_disagreement_score":0.00080438406,"about_ca_system_score_codex":0.00023148878,"about_ca_system_score_gemma":0.00014073499,"threshold_uncertainty_score":0.0016940832},"labels":[],"label_agreement":null},{"id":"W2922538610","doi":"10.1172/jci125534","title":"Heroin addiction engages negative emotional learning brain circuits in rats","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health; George Mason University","keywords":"Heroin; Amygdala; Functional magnetic resonance imaging; Abstinence; Addiction; Psychology; Opioid; Neuroscience; Opioid use disorder; Affect (linguistics); Medicine; Psychiatry; Drug; Internal medicine; Receptor","score_opus":0.1149252865583629,"score_gpt":0.3809536281211717,"score_spread":0.26602834156280875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922538610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988813,0.00008156121,0.000353298,0.0000734059,0.000013005091,0.0000110872425,0.00009753159,0.000026971653,0.00046188015],"genre_scores_gemma":[0.9948657,0.00028702297,0.0012278421,0.00008224037,0.000008718475,0.00007164196,0.00017598989,0.000013704008,0.0032670726],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999329,0.0000073321717,0.0000031149127,0.000016954937,0.00001478066,0.00002495513],"domain_scores_gemma":[0.99988663,0.0000075805588,0.000022942404,0.000014891467,0.0000109760595,0.000057044064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096382784,0.00035832645,0.00023517013,0.0004027775,0.00024287967,0.00022399354,0.0001390789,0.00022133155,0.0015360483],"category_scores_gemma":[0.00008501291,0.00021324774,0.00016029862,0.00009591857,0.000585979,0.00023489875,0.00019254284,0.0008644632,0.00019534827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002083105,0.0007396864,0.002186876,0.000030733267,0.000016778451,0.0001408994,0.000082859005,0.00011301077,0.98918766,0.00034816575,0.00012683311,0.0049434216],"study_design_scores_gemma":[0.0003437005,0.015839038,0.14250433,0.000044446704,0.00008940135,0.00092286465,0.0005507947,0.005643898,0.82935935,0.0013883531,0.0032679443,0.000045943478],"about_ca_topic_score_codex":0.0017247078,"about_ca_topic_score_gemma":0.005489277,"teacher_disagreement_score":0.0017247078,"about_ca_system_score_codex":0.00039083647,"about_ca_system_score_gemma":0.00030413189,"threshold_uncertainty_score":0.005138576},"labels":[],"label_agreement":null},{"id":"W2924316526","doi":"10.1172/jci125301","title":"Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Western Hospital; McGill University; McGill University Health Centre; Université de Montréal; Jewish General Hospital","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; Krembil Foundation; Institut Du Cancer de Montréal; Institute of Cancer Research; Terry Fox Research Institute; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Mitacs; Lady Davis Institute for Medical Research; Qatar University; McGill University; Kidney Foundation of Canada; Society for Immunotherapy of Cancer","keywords":"Immune system; Context (archaeology); Immunology; Cancer; Immunogenicity; Tumor-infiltrating lymphocytes; Disease; Biology; Immunotherapy; Medicine; Pathology; Genetics","score_opus":0.08151032616132131,"score_gpt":0.3913902125593313,"score_spread":0.30987988639801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924316526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877364,0.0029356855,0.00727417,0.00013569243,0.00001559101,0.00004720729,0.00088767614,0.00009933209,0.00086829363],"genre_scores_gemma":[0.995237,0.00066897215,0.00275537,0.000102822836,0.00002574209,0.00004681239,0.0006508704,0.000015873859,0.000496498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953914,0.00007555601,0.0000347647,0.00016286345,0.00010275705,0.00008493014],"domain_scores_gemma":[0.99936944,0.00013752693,0.000295006,0.00006545409,0.00006665919,0.000065890315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047412922,0.00039230252,0.000599739,0.00080764206,0.000216107,0.0008744389,0.00023349712,0.0003110725,0.00115955],"category_scores_gemma":[0.0006014853,0.00012423212,0.00027804953,0.0006818804,0.00042223005,0.00045130306,0.00046550273,0.00046575416,0.00023942922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001201542,0.00010308995,0.17309272,0.0005274248,0.00016476681,0.0006685108,0.00029095833,0.0007908314,0.78798723,0.0006461743,0.00029234376,0.034234386],"study_design_scores_gemma":[0.00006114249,0.0013174217,0.7446739,0.000114992465,0.00044654994,0.0043923813,0.0009075371,0.0076901456,0.22908066,0.0034474407,0.007817888,0.00004994404],"about_ca_topic_score_codex":0.00027778614,"about_ca_topic_score_gemma":0.0003234371,"teacher_disagreement_score":0.00115955,"about_ca_system_score_codex":0.00027428908,"about_ca_system_score_gemma":0.0002568389,"threshold_uncertainty_score":0.0038790703},"labels":[],"label_agreement":null},{"id":"W2927243788","doi":"10.1172/jci124358","title":"Cross-reactive public TCR sequences undergo positive selection in the human thymic repertoire","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; NIH Office of the Director; University of British Columbia; Human Islet Research Network; Massachusetts Institute of Technology; National Cancer Institute; National Institutes of Health; National Center for Research Resources; American Diabetes Association","keywords":"Negative selection; Complementarity determining region; T-cell receptor; Biology; Repertoire; Thymocyte; Genetics; Positive selection; T cell; Immunology; Gene; Peptide sequence; Immune system; Genome","score_opus":0.10368594887854125,"score_gpt":0.42211580882517546,"score_spread":0.3184298599466342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2927243788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980564,0.0003101478,0.0010642401,0.000007839397,9.070841e-7,0.0000040793116,0.000056745903,0.000017817687,0.0004817297],"genre_scores_gemma":[0.9986664,0.00016198223,0.0007607457,0.000020327754,0.0000025943084,0.000004936988,0.0001415144,0.000007763647,0.00023374073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979776,0.000035925495,0.000010319768,0.00005707556,0.00005790635,0.0000410045],"domain_scores_gemma":[0.99982256,0.000056158646,0.000046638525,0.000029085335,0.000021231104,0.000024357325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002368655,0.00011877687,0.00016684819,0.00020841579,0.00009373759,0.00032785392,0.000097574055,0.000143399,0.0011684613],"category_scores_gemma":[0.00028798883,0.00010453442,0.00011208095,0.00015646618,0.00012624793,0.00010469003,0.0001673887,0.00017073417,0.00027358913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018095794,0.000018604462,0.015589199,0.0000249658,0.00001427372,0.0001828183,0.00006350046,0.00017663174,0.97634125,0.000072478666,0.000032344924,0.0073029124],"study_design_scores_gemma":[0.0000317454,0.0010100908,0.24458641,0.00003261098,0.00011929375,0.008813778,0.0002292659,0.0034839427,0.73741186,0.00038836026,0.003878878,0.000013755415],"about_ca_topic_score_codex":0.0001762413,"about_ca_topic_score_gemma":0.00036043933,"teacher_disagreement_score":0.0011684613,"about_ca_system_score_codex":0.000081074955,"about_ca_system_score_gemma":0.00009955651,"threshold_uncertainty_score":0.0039088726},"labels":[],"label_agreement":null},{"id":"W2929664648","doi":"10.1172/jci123454","title":"The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; LabEx BRAIN; Société Francophone du Diabète; Université Paris Diderot; Agence Nationale de la Recherche; Institut National de la Recherche Agronomique; Institut National de la Santé et de la Recherche Médicale; Diabetes Canada; Diabète Québec","keywords":"Melanocortin; Energy homeostasis; Endocrinology; Internal medicine; Hypothalamus; Proopiomelanocortin; Arcuate nucleus; Arc (geometry); Anorectic; Melanocortin 4 receptor; Biology; Astrocyte; Homeostasis; Central nervous system; Chemistry; Hormone; Medicine; Body weight; Obesity","score_opus":0.04348003032928068,"score_gpt":0.3094163018950049,"score_spread":0.26593627156572425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2929664648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98604846,0.0052570663,0.0041945856,0.00020864054,0.00005843435,0.000023543644,0.00037394368,0.00017993264,0.0036554264],"genre_scores_gemma":[0.992626,0.002106183,0.0017111263,0.0000675934,0.000019163228,0.000020824076,0.00018187081,0.000028583941,0.0032385434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999449,0.0000061388596,0.0000030312567,0.0000130081435,0.000015264177,0.000017690852],"domain_scores_gemma":[0.99995697,0.0000015053146,0.000012921109,0.000002855746,0.000006157991,0.000019595545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004638036,0.00021842775,0.0001566546,0.0001956148,0.00013333543,0.00022854938,0.00010151787,0.00013447105,0.00078768056],"category_scores_gemma":[0.000046556506,0.00009572568,0.00013345602,0.00008993017,0.00020785218,0.00014827216,0.00025169333,0.0003904021,0.00023997386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012871553,0.00000698557,0.00038383628,0.000022229711,0.0000038502963,0.00006515637,0.000010450512,0.000023143104,0.99714416,0.00010029081,0.000046534442,0.002064709],"study_design_scores_gemma":[0.00006995472,0.00048468864,0.16328435,0.000041668187,0.00007729316,0.0009457863,0.00022634097,0.0026190951,0.8186185,0.0005603313,0.013046623,0.000025360338],"about_ca_topic_score_codex":0.0010100069,"about_ca_topic_score_gemma":0.0011761917,"teacher_disagreement_score":0.0010100069,"about_ca_system_score_codex":0.0002519536,"about_ca_system_score_gemma":0.00014208865,"threshold_uncertainty_score":0.0026350617},"labels":[],"label_agreement":null},{"id":"W2936477178","doi":"10.1172/jci79990","title":"ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation; Mount Sinai Hospital","funders":"NIH Clinical Center; Japan Science and Technology Agency; National Institutes of Health; National Institute of Neurological Disorders and Stroke; Tohoku Medical and Pharmaceutical University; Universität des Saarlandes; Centre National de la Recherche Scientifique; Agence Nationale de la Recherche; Universität Zürich; Eunice Kennedy Shriver National Institute of Child Health and Human Development; European Commission; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale","keywords":"Neurodegeneration; Fulminant; Biology; Medicine; Neuroscience; Bioinformatics; Immunology; Pathology; Disease","score_opus":0.058714423563480875,"score_gpt":0.3302542100886394,"score_spread":0.27153978652515853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2936477178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966731,0.0005498314,0.0014024379,0.00010413831,0.000036438338,0.000025316906,0.0003345239,0.00008528516,0.0007889315],"genre_scores_gemma":[0.9978218,0.00019784528,0.000597359,0.00004923096,0.000008200958,0.000018720499,0.00027667644,0.000019087942,0.0010110188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987555,0.000022166696,0.000018582785,0.000034451645,0.00002867331,0.000020497677],"domain_scores_gemma":[0.9998641,0.000029478395,0.000029671939,0.000013416897,0.000010109762,0.0000532039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012397426,0.00064765435,0.00028108672,0.00032586989,0.0001667938,0.00014926444,0.00028741558,0.00054833415,0.0017575852],"category_scores_gemma":[0.00017208733,0.0001164427,0.0002340595,0.00016382671,0.00037838763,0.00014352663,0.0002336615,0.0006196538,0.00029223305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000593693,0.00015657532,0.0018231742,0.000050671148,0.00004040133,0.00904893,0.000045058867,0.00019069419,0.9839361,0.0003019369,0.00019589822,0.0036169097],"study_design_scores_gemma":[0.0002204758,0.0025946172,0.035799522,0.000029690831,0.00013350972,0.06547026,0.00012001862,0.0032314223,0.88525915,0.0004768999,0.006636524,0.000027921285],"about_ca_topic_score_codex":0.00038208478,"about_ca_topic_score_gemma":0.00046608996,"teacher_disagreement_score":0.0017575852,"about_ca_system_score_codex":0.0002268445,"about_ca_system_score_gemma":0.00018325578,"threshold_uncertainty_score":0.00587976},"labels":[],"label_agreement":null},{"id":"W2943449347","doi":"10.1172/jci127195","title":"Aberrant splicing contributes to severe α-spectrin–linked congenital hemolytic anemia","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation; University of Manitoba","funders":"National Institute of General Medical Sciences; Yale University; National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Raymond and Beverly Sackler Institute for Biological, Physical and Engineering Sciences, Yale University","keywords":"Spectrin; RNA splicing; Hemolytic anemia; Genetics; Biology; Anemia; Medicine; Immunology; Computational biology; Virology; Gene; Internal medicine; RNA","score_opus":0.054068940630674855,"score_gpt":0.3502233516277379,"score_spread":0.296154410997063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943449347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985398,0.00054501445,0.00054585165,0.00004993886,0.00000441297,0.0000038211333,0.000020944504,0.000016826894,0.00027325578],"genre_scores_gemma":[0.99910563,0.00025637538,0.0004267802,0.000023101835,0.000013684788,0.0000015339724,0.000049577837,0.000003708514,0.00011946989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998909,0.000029517334,0.00001719473,0.000025205509,0.000027479196,0.000009695872],"domain_scores_gemma":[0.9998141,0.000049336828,0.00008035676,0.000014283282,0.000012580382,0.000029290237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017599779,0.00022602886,0.00015699163,0.00026318437,0.00012288052,0.00017222043,0.00010216386,0.00022457026,0.0006475205],"category_scores_gemma":[0.00054803974,0.00011002293,0.00009271349,0.0002111581,0.00035466618,0.000088936635,0.00015163691,0.00020906441,0.000163855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084723026,0.000113222006,0.23755807,0.00016583019,0.000086128595,0.032794204,0.000446101,0.0004731937,0.6879318,0.000912023,0.0005974497,0.038074784],"study_design_scores_gemma":[0.00010081931,0.0011054333,0.6857404,0.000049621805,0.00018536682,0.19555596,0.0002897252,0.0040682587,0.10621691,0.0020415492,0.004626613,0.000019366464],"about_ca_topic_score_codex":0.00013008936,"about_ca_topic_score_gemma":0.0001578707,"teacher_disagreement_score":0.0006475205,"about_ca_system_score_codex":0.00010254627,"about_ca_system_score_gemma":0.00008120882,"threshold_uncertainty_score":0.002166152},"labels":[],"label_agreement":null},{"id":"W2943584880","doi":"10.1172/jci123689","title":"CB1 agonism prolongs therapeutic window for hormone replacement in ovariectomized mice","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto; National Natural Science Foundation of China","keywords":"Ovariectomized rat; Agonist; Cannabinoid receptor; Internal medicine; Endocrinology; Medicine; Estrogen; Hormone; Menopause; Extinction (optical mineralogy); Cannabinoid; Downregulation and upregulation; Receptor; Chemistry","score_opus":0.11320208229566504,"score_gpt":0.3667983642229662,"score_spread":0.25359628192730116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943584880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868385,0.004513067,0.0030651751,0.00053300627,0.00018484965,0.00009935031,0.0022450443,0.0002804549,0.0022405738],"genre_scores_gemma":[0.97977054,0.0032887217,0.0042499113,0.00039828254,0.000048800855,0.00030544458,0.0016528888,0.00009448112,0.010190861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977475,0.00002442676,0.000022453849,0.0000618242,0.000051592684,0.000065043976],"domain_scores_gemma":[0.9998536,0.000013016336,0.00004296143,0.000017954271,0.000009875881,0.000062553234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026522222,0.00035866274,0.00049069646,0.00050110096,0.0002730893,0.00035964543,0.00036713496,0.00044249,0.0024843544],"category_scores_gemma":[0.00014296238,0.00024348366,0.0004184206,0.000205815,0.00045409857,0.00030539202,0.0002718359,0.0014422951,0.0005937381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010809904,0.00015287567,0.000253343,0.00006247471,0.00001190434,0.00008901686,0.000035148463,0.000041540992,0.99406517,0.00018732881,0.00015355235,0.0038667256],"study_design_scores_gemma":[0.0003399334,0.0029185975,0.008252449,0.000038385046,0.00008398117,0.00053849124,0.0001317696,0.00076335925,0.97421277,0.00028004887,0.012417687,0.00002253635],"about_ca_topic_score_codex":0.0006997668,"about_ca_topic_score_gemma":0.0015849107,"teacher_disagreement_score":0.0024843544,"about_ca_system_score_codex":0.00033313295,"about_ca_system_score_gemma":0.000334011,"threshold_uncertainty_score":0.008310974},"labels":[],"label_agreement":null},{"id":"W2945937650","doi":"10.1172/jci124012","title":"Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Alberta Children's Hospital; Hotchkiss Brain Institute","funders":"Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Glycolysis; Multiple sclerosis; Metabolism; Medicine; Neuroscience; Immunology; Pathology; Biology; Biochemistry","score_opus":0.0544415034306928,"score_gpt":0.3161607105607375,"score_spread":0.2617192071300447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945937650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944431,0.0026178288,0.0017546057,0.00008607606,0.00002537611,0.00001785044,0.00016729221,0.000039575072,0.00084829674],"genre_scores_gemma":[0.9953302,0.0014574707,0.0011006168,0.000046821642,0.00001197452,0.00003855107,0.00018676343,0.000009911181,0.001817695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991095,0.000015947982,0.000009725442,0.000018441693,0.000022057318,0.000022773733],"domain_scores_gemma":[0.9999474,0.0000059886675,0.0000140100365,0.00000471856,0.000012695249,0.000015051862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013049277,0.00024784912,0.0002101861,0.00032137037,0.00015920174,0.00023718865,0.000116179726,0.00022574585,0.00084127445],"category_scores_gemma":[0.00009837753,0.00011147203,0.00017279417,0.0001682233,0.00020975067,0.00019028102,0.00022271322,0.00036793787,0.00026755015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002636409,0.000019201358,0.00029965822,0.00005234175,0.0000051964325,0.00005000886,0.000025790468,0.000021038286,0.99816823,0.00004123723,0.000019212624,0.0010342583],"study_design_scores_gemma":[0.000031333708,0.0004691031,0.014690289,0.000017166754,0.000045865974,0.00032254946,0.00009653192,0.0005004256,0.9814921,0.00014772828,0.0021794527,0.0000073973615],"about_ca_topic_score_codex":0.00060950674,"about_ca_topic_score_gemma":0.0010876729,"teacher_disagreement_score":0.00084127445,"about_ca_system_score_codex":0.0001872235,"about_ca_system_score_gemma":0.00018766371,"threshold_uncertainty_score":0.002814293},"labels":[],"label_agreement":null},{"id":"W2947937089","doi":"10.1172/jci125957","title":"CD161 contributes to prenatal immune suppression of IFN-γ–producing PLZF+ T cells","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; University of California, San Francisco; Academy of Medical Sciences; National Institutes of Health; National Science Foundation","keywords":"Immunology; Immune system; Biology; Fetus; Population; Cord blood; T cell; Inflammation; Medicine; Pregnancy","score_opus":0.03484036600068894,"score_gpt":0.3267005005107754,"score_spread":0.29186013451008647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947937089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968906,0.00074826204,0.001529869,0.000056971992,0.000009033719,0.000011359136,0.00013124387,0.000042901243,0.0005797747],"genre_scores_gemma":[0.997375,0.0004623374,0.00084375945,0.000022342074,0.0000120528175,0.00001735096,0.00018191898,0.000014122759,0.0010711572],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99989724,0.000013365454,0.0000086366135,0.000031255815,0.00001836872,0.000031167914],"domain_scores_gemma":[0.99979645,0.000027190123,0.00008559119,0.000022762873,0.000015352169,0.00005271838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014169021,0.0002913995,0.0001669096,0.00025074676,0.00011776435,0.00022613662,0.00020966608,0.00022995661,0.0025619185],"category_scores_gemma":[0.00023358373,0.00014324757,0.00017457346,0.000097651966,0.00022352759,0.00011532717,0.0002248992,0.0004355322,0.0005574971],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023368372,0.0000168646,0.003583123,0.0000424873,0.0000031353616,0.00024930126,0.000037295446,0.000052776748,0.99294287,0.00006742939,0.000030126741,0.0027409098],"study_design_scores_gemma":[0.00007040037,0.0007991871,0.08884343,0.000043122553,0.000054424487,0.0043180874,0.0002670399,0.001413831,0.8986691,0.00024287165,0.00527012,0.000008361666],"about_ca_topic_score_codex":0.00040804758,"about_ca_topic_score_gemma":0.00035617454,"teacher_disagreement_score":0.0025619185,"about_ca_system_score_codex":0.00023865022,"about_ca_system_score_gemma":0.00018334718,"threshold_uncertainty_score":0.008570492},"labels":[],"label_agreement":null},{"id":"W2948057470","doi":"10.1172/jci127307","title":"Autophagy is required for lung development and morphogenesis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Bronchopulmonary dysplasia; Autophagy; Lung; BECN1; Biology; Cell biology; Morphogenesis; AMPK; Respiratory distress; Pathology; Immunology; Medicine; Internal medicine; Apoptosis; Gestational age; Genetics; Pregnancy","score_opus":0.08649733445057324,"score_gpt":0.40042435844838065,"score_spread":0.3139270239978074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948057470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9755265,0.017047979,0.0028225756,0.0003800057,0.00006995035,0.000032564792,0.0006830448,0.00020956037,0.0032278262],"genre_scores_gemma":[0.99203,0.0037074802,0.0015741629,0.000073574316,0.00001743528,0.000032754313,0.0005315592,0.000019839272,0.0020131986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980026,0.000034879497,0.000028888804,0.00005358152,0.00004755959,0.00003490782],"domain_scores_gemma":[0.9997838,0.000017010485,0.000090983245,0.00001989797,0.000024866747,0.000063467865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001669381,0.00017828813,0.00030802898,0.00024792994,0.00029467014,0.0004116695,0.00014760646,0.00036883113,0.0007603484],"category_scores_gemma":[0.00020261008,0.00016465782,0.00019844742,0.00010395211,0.00026468793,0.00019680934,0.0003960493,0.00047332657,0.00035887465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025940497,0.000020091453,0.003689197,0.00012240821,0.000010040434,0.00049545267,0.000041014326,0.00007549079,0.98961735,0.00042899858,0.00024519456,0.004995405],"study_design_scores_gemma":[0.000030090672,0.00047147906,0.20443852,0.000097542325,0.000054517943,0.005695634,0.00024361003,0.0013625873,0.76216996,0.00071918924,0.024690395,0.000026466689],"about_ca_topic_score_codex":0.0002940485,"about_ca_topic_score_gemma":0.00053107593,"teacher_disagreement_score":0.0007603484,"about_ca_system_score_codex":0.00035308197,"about_ca_system_score_gemma":0.00036176332,"threshold_uncertainty_score":0.0025618076},"labels":[],"label_agreement":null},{"id":"W2948271129","doi":"10.1172/jci123778","title":"Dectin-2–induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention; National Institutes of Health; Japan Blood Products Organization; Université Laval; Rheumatology Research Foundation; Massachusetts General Hospital; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Brigham and Women's Hospital","keywords":"Arteritis; Medicine; Immunology; Pathology; Biology","score_opus":0.07436483823168445,"score_gpt":0.39883623534167306,"score_spread":0.3244713971099886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948271129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99733305,0.00084196,0.00057013344,0.00006353875,0.000029153645,0.00002903301,0.000101852536,0.000026908156,0.0010043735],"genre_scores_gemma":[0.99729675,0.00041965177,0.0007019575,0.00008168695,0.00002965429,0.00003310056,0.0001927042,0.000003909939,0.001240684],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99985003,0.000026641042,0.000018603945,0.000022470322,0.000026876583,0.000055398446],"domain_scores_gemma":[0.99991584,0.00000874491,0.000021359756,0.000010218201,0.000012197588,0.0000316404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019512266,0.00031524838,0.00021146557,0.00020859907,0.00013916353,0.00022231459,0.00006811539,0.0002683682,0.0012057493],"category_scores_gemma":[0.00010389374,0.000112716414,0.0001630615,0.000083466264,0.00014774503,0.00013188343,0.00018379578,0.00056755147,0.00022078039],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019596412,0.000058848364,0.00076082745,0.000044032993,0.000003373843,0.00024671,0.00002133671,0.000017088536,0.9976774,0.000029107807,0.00003812105,0.0009071847],"study_design_scores_gemma":[0.00013499286,0.001557033,0.049569115,0.000022603419,0.00003019323,0.0024254636,0.00013308112,0.0010613346,0.9427026,0.00011961188,0.0022351379,0.000008776011],"about_ca_topic_score_codex":0.00015515285,"about_ca_topic_score_gemma":0.0003830684,"teacher_disagreement_score":0.0012057493,"about_ca_system_score_codex":0.00017302201,"about_ca_system_score_gemma":0.00013269036,"threshold_uncertainty_score":0.004033625},"labels":[],"label_agreement":null},{"id":"W2950595651","doi":"10.1172/jci130640","title":"The puzzle of lactational bone physiology: osteocytes masquerade as osteoclasts and osteoblasts","year":2019,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Calcium; Weaning; Lactation; Calcium metabolism; Skeleton (computer programming); Endocrinology; Internal medicine; Breastfeeding; Calcium supplementation; Calcium signaling; Physiology; Chemistry; Medicine; Biology; Pregnancy; Anatomy; Pathology","score_opus":0.06685007539413948,"score_gpt":0.39137645985771957,"score_spread":0.32452638446358006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950595651","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016643032,0.0384679,0.00021126254,0.945553,0.011779183,0.00000605676,0.00001073382,0.000019979238,0.0022875713],"genre_scores_gemma":[0.04105533,0.07685173,0.0009770666,0.6754065,0.1967255,0.000032441818,0.000021705571,0.00002674918,0.008902973],"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9989723,0.0004259883,0.00011882064,0.00012908097,0.0002694461,0.00008428039],"domain_scores_gemma":[0.9958366,0.0026236908,0.00024771705,0.00020085048,0.0006580153,0.00043311276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017199044,0.00045730107,0.0009193027,0.000519492,0.0014989361,0.0019441738,0.00069493434,0.009722281,0.002103377],"category_scores_gemma":[0.0061287326,0.0003401296,0.0004038063,0.00046942153,0.0040258095,0.003558395,0.0008620889,0.014472547,0.0018250037],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004160341,0.00014197812,0.0044607115,0.00042959343,0.000044407618,0.019785725,0.0007527748,0.00009299616,0.003064884,0.021914829,0.8473166,0.10157944],"study_design_scores_gemma":[0.00025771456,0.00018296044,0.0032377394,0.0006242123,0.000046265734,0.033718117,0.0014397756,0.00037764251,0.00093193015,0.03715289,0.92195404,0.00007680341],"about_ca_topic_score_codex":0.001285276,"about_ca_topic_score_gemma":0.0021715476,"teacher_disagreement_score":0.009722281,"about_ca_system_score_codex":0.0014815037,"about_ca_system_score_gemma":0.0012345327,"threshold_uncertainty_score":0.010749102},"labels":[],"label_agreement":null},{"id":"W2952553905","doi":"10.1172/jci124616","title":"More friend than foe: the emerging role of neutrophils in tissue repair","year":2019,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":419,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Deutsche Forschungsgemeinschaft; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Collateral damage; Inflammation; Immune system; Biology; Immunology; Infiltration (HVAC); Bone marrow; Cell biology","score_opus":0.10202073006737516,"score_gpt":0.40570153098009915,"score_spread":0.303680800912724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952553905","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000087942,0.99662006,0.00011692285,0.0016736737,0.0007696223,0.0000014271332,0.0000076049673,0.0000051608017,0.0007175595],"genre_scores_gemma":[0.000828199,0.99644214,0.00015132755,0.000786123,0.001020303,0.0000028695488,0.000013280584,0.000001603192,0.00075406575],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99979573,0.000048428723,0.000021304768,0.00003371738,0.00007963292,0.000021182947],"domain_scores_gemma":[0.99943084,0.00028968148,0.000048841906,0.000017853932,0.000142077,0.00007060257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000714936,0.0005084513,0.00087930914,0.001250706,0.00033379294,0.0012800577,0.0006913283,0.0014393554,0.0030455117],"category_scores_gemma":[0.0011473508,0.00013171729,0.0003431755,0.0011426427,0.0008792698,0.0024304676,0.00061571447,0.0025463873,0.0016371562],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085347,0.000037326008,0.0002556654,0.007862475,0.00006591515,0.0003509957,0.0001334057,0.00018255207,0.0014573648,0.0115667265,0.08512258,0.89287966],"study_design_scores_gemma":[0.000007390367,0.000053011336,0.00046933471,0.0019355757,0.000028721666,0.0012707793,0.00010411782,0.000039776536,0.00016998721,0.0041437093,0.991767,0.000010558988],"about_ca_topic_score_codex":0.0005095971,"about_ca_topic_score_gemma":0.0010445606,"teacher_disagreement_score":0.0030455117,"about_ca_system_score_codex":0.0005914473,"about_ca_system_score_gemma":0.0011115528,"threshold_uncertainty_score":0.010188222},"labels":[],"label_agreement":null},{"id":"W2953645244","doi":"10.1172/jci125628","title":"T follicular helper cells in human efferent lymph retain lymphoid characteristics","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":160,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Center for Advancing Translational Sciences; Center for AIDS Research, University of Washington; National Institutes of Health; Vetenskapsrådet; National Institute of Allergy and Infectious Diseases; Pediatric Infectious Diseases Society; Karolinska Institutet; Parker Institute for Cancer Immunotherapy; University of Pennsylvania; Children's Hospital of Philadelphia; National Institute of General Medical Sciences; U.S. Department of Veterans Affairs","keywords":"Lymphatic system; Lymph; Efferent; Pathology; Follicular phase; Immunology; Biology; Medicine; Anatomy; Endocrinology","score_opus":0.034647114051272035,"score_gpt":0.31319030741519654,"score_spread":0.2785431933639245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953645244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9723451,0.009003206,0.004855287,0.000097967495,0.000042903892,0.00011448121,0.0010454609,0.0003744663,0.012121103],"genre_scores_gemma":[0.98858064,0.0015158372,0.0016801645,0.00010137095,0.000049423812,0.00006809268,0.0014617442,0.000032890217,0.0065097488],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998628,0.00001854325,0.000010230618,0.000046996523,0.00002334569,0.000038032493],"domain_scores_gemma":[0.9999262,0.000015378002,0.000009022795,0.000016653199,0.000016033106,0.00001661668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014231754,0.00016922815,0.00019323472,0.00033994805,0.0002491843,0.00055486907,0.00013857058,0.00028577365,0.0046693115],"category_scores_gemma":[0.00025785025,0.00014274266,0.00015187814,0.00023144862,0.00016172304,0.00027480762,0.00025193056,0.00030552686,0.0018068358],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006461817,0.00008074218,0.018559536,0.00020554748,0.000015053476,0.0013173844,0.0004467714,0.00012456161,0.93724334,0.0007728784,0.00079587067,0.039792113],"study_design_scores_gemma":[0.00021602059,0.0026112546,0.23799269,0.00020069884,0.0001501016,0.01597106,0.0015646436,0.0014848402,0.6093351,0.0018917524,0.12853889,0.000042994616],"about_ca_topic_score_codex":0.00078472274,"about_ca_topic_score_gemma":0.00052868546,"teacher_disagreement_score":0.0046693115,"about_ca_system_score_codex":0.00017371334,"about_ca_system_score_gemma":0.00020051603,"threshold_uncertainty_score":0.01562041},"labels":[],"label_agreement":null},{"id":"W2953671780","doi":"10.1172/jci125538","title":"Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiovascular Effects of Exercise","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute; Hospital for Sick Children; University of British Columbia; Dalhousie University; Toronto General Hospital; University of Toronto; Western University","funders":"National Center for Advancing Translational Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Fondation Leducq; Johns Hopkins University; Canadian Institutes of Health Research; Ohio State University","keywords":"Wnt signaling pathway; Cardiomyopathy; Ankyrin; Sudden cardiac death; Plakoglobin; Phenotype; Medicine; Ankyrin repeat; Sudden death; Catenin; Cancer research; Heart failure; Internal medicine; Biology; Cell biology; Signal transduction; Genetics","score_opus":0.03772923377244257,"score_gpt":0.3416868653558006,"score_spread":0.30395763158335803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953671780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862962,0.004563399,0.0029653101,0.00054816954,0.000060200742,0.0000552254,0.000045071592,0.000074868105,0.0053914986],"genre_scores_gemma":[0.99715793,0.0010989169,0.00068625377,0.00009720662,0.000033787033,0.000024850635,0.0000602037,0.0000049133896,0.00083589903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994326,0.000018755183,0.000005878953,0.000011344208,0.0000068528443,0.000013991978],"domain_scores_gemma":[0.99994123,0.000009179558,0.00001786467,0.000005295987,0.000004030331,0.000022305296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012448042,0.0002532894,0.00031105618,0.00022596444,0.00016959467,0.00017564424,0.00010926962,0.00030803427,0.0013357557],"category_scores_gemma":[0.00023763959,0.00005803242,0.00015981376,0.00011792077,0.00016933694,0.000104119164,0.00023510601,0.00035651185,0.00018849634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042771767,0.0015095574,0.04282727,0.00034145568,0.00016745225,0.03483067,0.00019709633,0.00072900445,0.7905557,0.0030739133,0.0014169421,0.120073766],"study_design_scores_gemma":[0.0019490463,0.015056093,0.5617396,0.0005373138,0.00062885357,0.18716012,0.0008902431,0.006782143,0.16880322,0.0074546365,0.048901025,0.00009770385],"about_ca_topic_score_codex":0.00010253326,"about_ca_topic_score_gemma":0.00016297461,"teacher_disagreement_score":0.0013357557,"about_ca_system_score_codex":0.000095433206,"about_ca_system_score_gemma":0.00010575803,"threshold_uncertainty_score":0.00446862},"labels":[],"label_agreement":null},{"id":"W2953812088","doi":"10.1172/jci126744","title":"Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Eosinophilic Esophagitis","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Colorado School of Medicine, Anschutz Medical Campus; National Institute of Diabetes and Digestive and Kidney Diseases; Queen's University Belfast; Queen's University; National Institutes of Health; Rare Diseases Clinical Research Network; National Center for Advancing Translational Sciences; Children's Hospital Colorado; Wellcome Trust; American Partnership for Eosinophilic Disorders; Meso Scale Diagnostics; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"Eosinophilic esophagitis; Claudin; Skin barrier; Tight junction; Epithelium; Eosinophilic; Pathology; Medicine; Cancer research; Biology; Cell biology; Dermatology; Disease","score_opus":0.03895611579644659,"score_gpt":0.33516948268736174,"score_spread":0.29621336689091515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953812088","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869279,0.008724434,0.0024090956,0.00035556973,0.00004020993,0.000035701498,0.00020658059,0.000108165725,0.0011922375],"genre_scores_gemma":[0.9972051,0.0013718376,0.00041432132,0.00006456472,0.000011110052,0.000015979718,0.00010836176,0.000005252663,0.00080348086],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999455,0.0000111234585,0.0000036139627,0.000012062281,0.000008463209,0.000019238005],"domain_scores_gemma":[0.99995863,0.000003045671,0.000014096907,0.0000022682252,0.0000054426428,0.000016529215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015080649,0.0001932865,0.00019337056,0.00015519488,0.00014878556,0.00026502655,0.00008938896,0.00022701891,0.00077851466],"category_scores_gemma":[0.00007333886,0.00008503504,0.00012302262,0.00009096689,0.0002491465,0.00015432187,0.0001269849,0.00058161747,0.00012294392],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075161795,0.00009253814,0.001943106,0.00009661754,0.000012415033,0.00018589997,0.000033115342,0.00011962517,0.9906501,0.00020351373,0.00021118288,0.0057002394],"study_design_scores_gemma":[0.00020830925,0.0021280854,0.15171392,0.000052752024,0.00011608839,0.0016691423,0.0003136321,0.0033181126,0.82880425,0.0004735401,0.011184573,0.000017625132],"about_ca_topic_score_codex":0.0002206015,"about_ca_topic_score_gemma":0.00031219318,"teacher_disagreement_score":0.00077851466,"about_ca_system_score_codex":0.00027599366,"about_ca_system_score_gemma":0.00014992243,"threshold_uncertainty_score":0.002604425},"labels":[],"label_agreement":null},{"id":"W2962835311","doi":"10.1172/jci129107","title":"Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; University of North Carolina at Chapel Hill; National Institutes of Health; Hospital for Sick Children","keywords":"Ubiquitin ligase; Biology; Cell biology; Dwarfism; Ubiquitin; Mutation; Phosphorylation; Genetics; Gene","score_opus":0.0736757577449552,"score_gpt":0.34207948890820883,"score_spread":0.2684037311632536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2962835311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99508226,0.00067715574,0.0028074328,0.000103184226,0.000017976343,0.000014696033,0.00030282416,0.00013193852,0.0008624814],"genre_scores_gemma":[0.99818003,0.00021734055,0.0009142202,0.000031021944,0.000004313883,0.0000059925983,0.00012937971,0.0000111936615,0.00050650485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998839,0.000021875203,0.000013179591,0.00003229294,0.000032198288,0.000016548325],"domain_scores_gemma":[0.99987936,0.000018324929,0.000052449832,0.000007387437,0.000005892711,0.000036627862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010408711,0.00052213523,0.0002529583,0.0004960322,0.00015721154,0.00016272895,0.00015317266,0.00041479708,0.0013050645],"category_scores_gemma":[0.0001706276,0.00014455413,0.00023870393,0.0001631917,0.0004938415,0.00010058117,0.00029825032,0.00034314228,0.00019513306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026753073,0.000016625507,0.0060673705,0.000058833084,0.00002417475,0.009925598,0.000048172184,0.00016233308,0.9803295,0.0005179252,0.00014999001,0.0024319538],"study_design_scores_gemma":[0.0001137208,0.00044200022,0.15765664,0.000040097446,0.00012449356,0.08950708,0.00012545346,0.004249335,0.7397479,0.00095032103,0.007016363,0.00002651068],"about_ca_topic_score_codex":0.00085325626,"about_ca_topic_score_gemma":0.0010970723,"teacher_disagreement_score":0.0013050645,"about_ca_system_score_codex":0.00032973406,"about_ca_system_score_gemma":0.00020970646,"threshold_uncertainty_score":0.004365921},"labels":[],"label_agreement":null},{"id":"W2963503058","doi":"10.1172/jci120633","title":"Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences; National Institutes of Health; Chinese Academy of Agricultural Sciences; China Scholarship Council; National Institute of Mental Health; Robert Mapplethorpe Foundation; Crohn's and Colitis Foundation; U.S. Department of Defense","keywords":"Bromodomain; BRD4; Epigenetics; Chromatin; Provirus; Biology; Histone; BET inhibitor; Transactivation; Small molecule; Drug discovery; Virology; Transcription factor; Genetics; Bioinformatics; Genome; DNA","score_opus":0.09694265488467114,"score_gpt":0.3596081667909881,"score_spread":0.262665511906317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963503058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91416955,0.016164305,0.046286892,0.0011933277,0.0002201408,0.0009754582,0.0012046483,0.0005418173,0.019243907],"genre_scores_gemma":[0.9659481,0.0073485374,0.017273635,0.00058383425,0.000023536015,0.00022225754,0.00091274135,0.000021291262,0.0076662335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999399,0.000009567035,0.0000037460334,0.00001269519,0.00001753439,0.000016615671],"domain_scores_gemma":[0.9999788,0.000002337131,0.000006761513,0.0000018501016,0.000004666087,0.000005616927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014562077,0.0004058447,0.00025708487,0.00029333675,0.000117023636,0.00035423468,0.00039925953,0.00036715282,0.0012322617],"category_scores_gemma":[0.00008643426,0.00016343697,0.00022574562,0.00014548378,0.00017723371,0.00021847482,0.00027906802,0.00039897967,0.00036071433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033487985,0.00028883596,0.00030400278,0.000228507,0.000026796251,0.00015551469,0.00001880238,0.002019848,0.9637214,0.0018747689,0.00072266377,0.030303994],"study_design_scores_gemma":[0.0006484433,0.0033698434,0.00134587,0.000036702917,0.00007959936,0.0005416505,0.000024413786,0.009383974,0.956103,0.0005185593,0.027924646,0.000023427894],"about_ca_topic_score_codex":0.00035486592,"about_ca_topic_score_gemma":0.0009358026,"teacher_disagreement_score":0.0012322617,"about_ca_system_score_codex":0.00047097745,"about_ca_system_score_gemma":0.00025065854,"threshold_uncertainty_score":0.004122317},"labels":[],"label_agreement":null},{"id":"W2966674500","doi":"10.1172/jci128865","title":"Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust; Medical Research Council; Bill and Melinda Gates Foundation","keywords":"Immunology; Innate immune system; Colonization; Immune system; Acquired immune system; Streptococcus pneumoniae; Microbiology; Pneumococcal infections; Biology; Medicine; Antibiotics","score_opus":0.0726633202950458,"score_gpt":0.4028023871286754,"score_spread":0.3301390668336296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2966674500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992397,0.00022175124,0.00013901448,0.000021944288,0.000015796399,0.000029558596,0.000054565313,0.000008221091,0.0002694668],"genre_scores_gemma":[0.99877733,0.00015527404,0.00023701227,0.00006442505,0.000014645951,0.000052852665,0.00019984545,0.000003158363,0.00049546856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99971205,0.00007523191,0.00001899226,0.00005016326,0.000059965405,0.000083634186],"domain_scores_gemma":[0.9998254,0.000043847907,0.00002729801,0.000024252371,0.00001923773,0.00005997661],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035355453,0.00030222995,0.0004512263,0.00020054853,0.00018522769,0.00024820596,0.00010829227,0.00040356827,0.0014583617],"category_scores_gemma":[0.00040976584,0.00015868963,0.00021206343,0.0000838129,0.00038213833,0.00019585779,0.00023213461,0.0008623974,0.00019087357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004187748,0.00072303193,0.0038621712,0.00007038042,0.000014650747,0.00048000333,0.00013523281,0.00006925968,0.9870559,0.000044659402,0.00006618788,0.0032907175],"study_design_scores_gemma":[0.00042556218,0.050753165,0.2373924,0.00005240021,0.00008742222,0.00398264,0.000711824,0.0019218791,0.70243335,0.00022179152,0.0019890433,0.000028610062],"about_ca_topic_score_codex":0.000312178,"about_ca_topic_score_gemma":0.00058049907,"teacher_disagreement_score":0.0014583617,"about_ca_system_score_codex":0.00021189787,"about_ca_system_score_gemma":0.00020375777,"threshold_uncertainty_score":0.0048787594},"labels":[],"label_agreement":null},{"id":"W2967668820","doi":"10.1172/jci130755","title":"Antiobesogenic effects of central GIPR antagonism","year":2019,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Diabetes Canada; University of Toronto; University Health Network; Toronto General Hospital; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta; Toronto General Hospital Research Institute, University Health Network; Canadian Institutes of Health Research; University of Toronto; Diabetes Canada","keywords":"Overnutrition; Leptin; Endocrinology; Internal medicine; Hormone; Obesity; Appetite; Antagonism; Biology; Medicine; Receptor","score_opus":0.046430447532636566,"score_gpt":0.3436032822189328,"score_spread":0.29717283468629624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2967668820","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016916288,0.042437714,0.0010193536,0.8768477,0.024936939,0.000058589107,0.00012327911,0.00024865166,0.037411418],"genre_scores_gemma":[0.1601516,0.043689467,0.0018755686,0.63496226,0.12959513,0.00013026242,0.0001375474,0.000063948406,0.029394288],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996954,0.00009889534,0.000025961284,0.000040411684,0.00009675029,0.000042558295],"domain_scores_gemma":[0.99906105,0.0005149394,0.00008356738,0.00004841917,0.00017551011,0.000116501345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005064273,0.00037268584,0.0005793295,0.00019686659,0.0005019765,0.00075902947,0.0003731494,0.0037998145,0.0036854164],"category_scores_gemma":[0.0026104928,0.00010395647,0.00037307382,0.00013682443,0.00074682175,0.0005938355,0.0002765832,0.006263159,0.0025883573],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013157317,0.00033416433,0.0028485742,0.00060608477,0.0000872834,0.02653619,0.00013771644,0.00028361878,0.010609113,0.010435414,0.68725294,0.25955316],"study_design_scores_gemma":[0.00089143275,0.0008594637,0.0043713464,0.000558482,0.000078590754,0.039085895,0.00019082963,0.001212293,0.004945089,0.0146930665,0.9330678,0.000045614986],"about_ca_topic_score_codex":0.0003680412,"about_ca_topic_score_gemma":0.0009344964,"teacher_disagreement_score":0.0037998145,"about_ca_system_score_codex":0.0008983335,"about_ca_system_score_gemma":0.00045533155,"threshold_uncertainty_score":0.012328923},"labels":[],"label_agreement":null},{"id":"W2968883182","doi":"10.1172/jci126091","title":"Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6 blockade–refractory idiopathic multicentric Castleman disease","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Prevention of Organ Failure","funders":"National Heart, Lung, and Blood Institute; Penn Center for Precision Medicine, University of Pennsylvania; National Cancer Institute; National Institutes of Health; Janssen Pharmaceuticals; Celgene; Children's Hospital of Philadelphia; University of Pennsylvania","keywords":"Medicine; Myelofibrosis; Organomegaly; Blockade; Interleukin 6; Anasarca; Refractory (planetary science); Castleman disease; Immunology; Cytokine; Internal medicine; Disease; Receptor","score_opus":0.052298794727512546,"score_gpt":0.3519851468420589,"score_spread":0.29968635211454636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2968883182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99646145,0.0024466491,0.00038723703,0.000050837018,0.0000047331814,0.000028464217,0.000036111225,0.000009105184,0.0005754354],"genre_scores_gemma":[0.9985274,0.0004529325,0.0007921493,0.000050824598,0.000009055588,0.000009693931,0.00007308217,0.0000016718212,0.00008314334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999262,0.000012810507,0.000007632379,0.0000142933595,0.000020010099,0.000019024283],"domain_scores_gemma":[0.9999231,0.000014091164,0.000023423372,0.000007015896,0.000008589737,0.00002373105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022495752,0.00022669078,0.00025787117,0.00029835556,0.0001810913,0.00023680045,0.00017549357,0.00018872223,0.000424305],"category_scores_gemma":[0.00014114448,0.00006241571,0.00014611676,0.00014938788,0.00016921363,0.0000884655,0.00012000034,0.00025426038,0.00010486528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024113206,0.0005414677,0.09308274,0.0004324503,0.000081426166,0.005566558,0.00023431121,0.00079970784,0.84521717,0.00019416747,0.00042950234,0.051009167],"study_design_scores_gemma":[0.0008013794,0.0089698685,0.5715912,0.00011189043,0.0003392864,0.058301166,0.00040691273,0.008477386,0.337805,0.00041558902,0.012748066,0.00003234853],"about_ca_topic_score_codex":0.00024254761,"about_ca_topic_score_gemma":0.00073445705,"teacher_disagreement_score":0.000424305,"about_ca_system_score_codex":0.00021584587,"about_ca_system_score_gemma":0.00018688124,"threshold_uncertainty_score":0.0015660524},"labels":[],"label_agreement":null},{"id":"W2969087302","doi":"10.1172/jci127374","title":"Degradation of splicing factor SRSF3 contributes to progressive liver disease","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Diego; National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; University of Minnesota; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Government of Ontario; U.S. Department of Veterans Affairs","keywords":"Splicing factor; Nonalcoholic fatty liver disease; RNA splicing; Cirrhosis; Hepatocellular carcinoma; Cancer research; Biology; Liver disease; Steatosis; Alternative splicing; Fatty liver; Internal medicine; Medicine; Endocrinology; RNA; Gene; Biochemistry; Exon; Disease","score_opus":0.0531995048928869,"score_gpt":0.3806341115405284,"score_spread":0.3274346066476415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969087302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99289674,0.0035063655,0.00233318,0.00015457816,0.000018437815,0.000011370198,0.00013124984,0.00008054536,0.00086759956],"genre_scores_gemma":[0.9967127,0.0014057641,0.00067038904,0.000052072584,0.000013338879,0.000005872693,0.0001488249,0.000010944881,0.0009801029],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999218,0.000018691855,0.000009824604,0.00001941789,0.000018605688,0.000011701695],"domain_scores_gemma":[0.99988616,0.000012876722,0.000050174345,0.000009721194,0.000012915586,0.000028225733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019409928,0.00034810713,0.0002980707,0.00020700075,0.00012094902,0.00017530072,0.00009414472,0.0002477128,0.0010628828],"category_scores_gemma":[0.00014477456,0.00011186335,0.00021837486,0.00012382408,0.00028949327,0.000101748614,0.00018905938,0.00034710698,0.00025568006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072113116,0.000038760052,0.008213756,0.0000820699,0.000033649245,0.0011847224,0.00002955376,0.000084980544,0.98354185,0.0001709179,0.00013526033,0.0057632066],"study_design_scores_gemma":[0.00013569601,0.0013858731,0.27967554,0.000045275527,0.00022833141,0.021589696,0.0001588615,0.002397588,0.68227047,0.00095573143,0.011134423,0.000022590842],"about_ca_topic_score_codex":0.00036559175,"about_ca_topic_score_gemma":0.0004887969,"teacher_disagreement_score":0.0010628828,"about_ca_system_score_codex":0.00013787269,"about_ca_system_score_gemma":0.00013512284,"threshold_uncertainty_score":0.0035556555},"labels":[],"label_agreement":null},{"id":"W2969745156","doi":"10.1172/jci128903","title":"Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child, Adolescent and Family Mental Health","funders":"Oesterreichische Nationalbank; Universität Wien; Medizinische Universität Wien; European Commission; Cancer Research Institute; Österreichischen Akademie der Wissenschaften; Wellcome Trust; Centers for Disease Control and Prevention; Austrian Science Fund; Jeffrey Modell Foundation","keywords":"Immunodeficiency; Medicine; Virology; Immunologic Deficiency Syndromes; Biology; Genetics","score_opus":0.026068335197268106,"score_gpt":0.3085938198216083,"score_spread":0.2825254846243402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969745156","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920814,0.0026411484,0.0025322451,0.00019919025,0.00004897202,0.000040332798,0.00027409408,0.00019191817,0.0019907241],"genre_scores_gemma":[0.99762875,0.0006631859,0.0009600526,0.0000978579,0.000022644872,0.000007995246,0.00013660436,0.000013932062,0.00046908404],"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999808,0.00003393066,0.000037091024,0.000053867116,0.000042455697,0.000024770377],"domain_scores_gemma":[0.9997464,0.00006501441,0.00008499021,0.000017574017,0.000021738151,0.00006431913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019193941,0.0013006353,0.0003284499,0.0007628785,0.0002597299,0.00020876066,0.00022022493,0.00048711806,0.001218122],"category_scores_gemma":[0.0006228695,0.00023128184,0.0001638514,0.00044933194,0.00054744066,0.00018363219,0.00047356597,0.00037812462,0.0002875389],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012205024,0.00016346166,0.1971965,0.00074949564,0.00020396305,0.38704982,0.0010865374,0.00054737297,0.36911395,0.0019045089,0.0023621775,0.03840169],"study_design_scores_gemma":[0.00011933119,0.0008699577,0.15712251,0.00014833258,0.00022504391,0.7864981,0.00038963763,0.0014839405,0.04380308,0.0011939193,0.008114146,0.000031896347],"about_ca_topic_score_codex":0.00048398488,"about_ca_topic_score_gemma":0.0004364829,"teacher_disagreement_score":0.0013006353,"about_ca_system_score_codex":0.00019144498,"about_ca_system_score_gemma":0.00022352929,"threshold_uncertainty_score":0.0040749907},"labels":[],"label_agreement":null},{"id":"W2971459028","doi":"10.1172/jci129338","title":"Killers 2.0: NK cell therapies at the forefront of cancer control","year":2019,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":215,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Terry Fox Research Institute; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Chimeric antigen receptor; Oncolytic virus; Cancer immunotherapy; NK-92; Immunology; Cytotoxic T cell; Immunotherapy; Adoptive cell transfer; Cancer; Cancer research; Lymphokine-activated killer cell; Cancer cell; Interleukin 21; Medicine; Biology; Antigen; T cell; Immune system; CD8; Internal medicine","score_opus":0.1088544605288628,"score_gpt":0.3971898933091839,"score_spread":0.28833543278032114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971459028","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000100071746,0.99701214,0.00021716951,0.00062793534,0.00069315627,0.000005782897,0.00001216443,0.00001200075,0.0013194993],"genre_scores_gemma":[0.0008318429,0.9962739,0.00027628487,0.00060048763,0.00046007274,0.000010934159,0.000032264354,0.0000028953082,0.0015113624],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99979705,0.000036582333,0.000022848537,0.000030363733,0.00008519838,0.000027951182],"domain_scores_gemma":[0.99972457,0.00010243148,0.00003132014,0.000009051049,0.00008261317,0.000050027586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072579796,0.00088723033,0.0011708316,0.0017200918,0.00029249702,0.0011633846,0.0009695348,0.0014982519,0.0030096408],"category_scores_gemma":[0.00064875925,0.00029473787,0.00037579704,0.001437958,0.0007724031,0.0018676674,0.000851917,0.003423791,0.0028243016],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008914169,0.0000613026,0.00011117545,0.00636328,0.000040717143,0.00014570514,0.000044795695,0.0003676501,0.0019669912,0.008299792,0.04276325,0.93974614],"study_design_scores_gemma":[0.000015257058,0.00006785194,0.00024504968,0.0013250578,0.00002349738,0.0005367838,0.000025819378,0.00007138776,0.00036026892,0.002281307,0.99503726,0.000010384484],"about_ca_topic_score_codex":0.0006909967,"about_ca_topic_score_gemma":0.0012108,"teacher_disagreement_score":0.0030096408,"about_ca_system_score_codex":0.00092691724,"about_ca_system_score_gemma":0.0010946222,"threshold_uncertainty_score":0.010068297},"labels":[],"label_agreement":null},{"id":"W2971894914","doi":"10.1172/jci128205","title":"Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital de l'Enfant-Jésus","funders":"Medical Research Council; Association Française contre les Myopathies","keywords":"Myotonic dystrophy; Oligonucleotide; Conjugated system; Peptide; Medicine; Neuroscience; Biochemistry; Chemistry; Internal medicine; Psychology; Gene","score_opus":0.044318714219908,"score_gpt":0.30659695475364984,"score_spread":0.2622782405337418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971894914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98953116,0.0011603617,0.0063403617,0.00011756665,0.00005761972,0.00011681093,0.00053139596,0.00032483827,0.0018200633],"genre_scores_gemma":[0.9890258,0.0010394412,0.0050522797,0.000077666235,0.000016813343,0.00015756515,0.00066463294,0.000054792912,0.0039110207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997831,0.000032833603,0.000028071538,0.00006628795,0.00004678235,0.000042830565],"domain_scores_gemma":[0.99989545,0.000017529997,0.00003778832,0.000011394386,0.000008449592,0.000029403736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021309225,0.00051326666,0.00033777888,0.00023463058,0.00011640273,0.00022229402,0.00017515519,0.0005200558,0.0012368496],"category_scores_gemma":[0.00009365833,0.00016737147,0.00022349712,0.0001246517,0.00023289303,0.00015645933,0.00017009559,0.0006642979,0.00040806725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004462596,0.000024065175,0.000027137237,0.000021276242,0.000002905743,0.0000259849,0.000008684913,0.000035643476,0.9991725,0.000050315477,0.000022266562,0.0005644753],"study_design_scores_gemma":[0.00002380474,0.0005983809,0.00079426094,0.000003978395,0.000013951776,0.00022155188,0.000009532858,0.00046373258,0.99653876,0.000019590883,0.0013095174,0.0000030333129],"about_ca_topic_score_codex":0.00019818742,"about_ca_topic_score_gemma":0.00030707748,"teacher_disagreement_score":0.0012368496,"about_ca_system_score_codex":0.00016366762,"about_ca_system_score_gemma":0.00012999885,"threshold_uncertainty_score":0.004137695},"labels":[],"label_agreement":null},{"id":"W2972255989","doi":"10.1172/jci128877","title":"Targeting innate immunity for tuberculosis vaccination","year":2019,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":137,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases; Radboud Universitair Medisch Centrum; International Society for Advancement of Cytometry; National Heart, Lung, and Blood Institute; Bill and Melinda Gates Foundation","keywords":"Innate immune system; Immunology; Immunity; Acquired immune system; Immune system; Vaccination; Biology; Mycobacterium tuberculosis; Tuberculosis; Tuberculosis vaccines; Reprogramming; Myeloid; Medicine; Cell; Genetics","score_opus":0.15123186389129226,"score_gpt":0.4363802498010197,"score_spread":0.28514838590972746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972255989","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009332893,0.9968839,0.00024414188,0.00050886854,0.0008658644,0.0000064009196,0.000014963876,0.000012106299,0.0013703629],"genre_scores_gemma":[0.00088456215,0.9964489,0.00030840602,0.00050730316,0.00043663816,0.000013756586,0.000035504407,0.000003573211,0.0013612903],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997894,0.00004325924,0.00002676931,0.000035587713,0.00007867855,0.000026293088],"domain_scores_gemma":[0.9997429,0.000110020585,0.000031749994,0.0000123090895,0.000065144835,0.000037902046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007640488,0.0008603549,0.0010215056,0.0016860691,0.00025993452,0.0008721108,0.0010509003,0.0016625719,0.004882819],"category_scores_gemma":[0.0007358235,0.0003038354,0.0005436673,0.0011030871,0.0006226977,0.0015795473,0.0008036922,0.003394368,0.004441598],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096195734,0.00008405101,0.00010233002,0.011387545,0.00006748254,0.00018889757,0.000055661345,0.00041716933,0.0030768209,0.011218532,0.061879296,0.911426],"study_design_scores_gemma":[0.000015769378,0.00006524778,0.00024510577,0.0016061183,0.000030093097,0.000493435,0.00001752433,0.00006042202,0.00033246633,0.0024555747,0.99466914,0.000009084899],"about_ca_topic_score_codex":0.0005045932,"about_ca_topic_score_gemma":0.0010417516,"teacher_disagreement_score":0.004882819,"about_ca_system_score_codex":0.00077340077,"about_ca_system_score_gemma":0.0008588446,"threshold_uncertainty_score":0.016334653},"labels":[],"label_agreement":null},{"id":"W2973418595","doi":"10.1172/jci127286","title":"Peritoneal GATA6+ macrophages function as a portal for Staphylococcus aureus dissemination","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University; University of Calgary","funders":"University of Calgary; Deutsche Forschungsgemeinschaft; University of Southern California","keywords":"Staphylococcus aureus; Peritoneum; Peritoneal cavity; Peritoneal dialysis; Medicine; Vancomycin; Microbiology; Sepsis; Antibiotics; Macrophage; Peritonitis; Immunology; Pathology; Biology; Bacteria; Internal medicine; Surgery; In vitro","score_opus":0.05161919600814548,"score_gpt":0.41123092769775976,"score_spread":0.3596117316896143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2973418595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9847053,0.0038401969,0.008236948,0.00045771932,0.000102206985,0.00007332014,0.00025514577,0.0001457917,0.002183438],"genre_scores_gemma":[0.9905329,0.0013371299,0.0055147037,0.00013613878,0.000031817384,0.000034887154,0.0001324246,0.00001497036,0.0022651872],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998621,0.00004140731,0.000012031451,0.000024393343,0.000019968651,0.00004005541],"domain_scores_gemma":[0.9998592,0.000017385519,0.000037696424,0.000014815614,0.000019109724,0.00005185825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021089615,0.0002854877,0.00017916408,0.00015261256,0.000100294616,0.00022572304,0.00015894175,0.00032788332,0.0018641914],"category_scores_gemma":[0.00018908894,0.000113738235,0.00017907697,0.000048776128,0.00021041367,0.00031793045,0.00023418695,0.00044364814,0.0003554627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037223217,0.00002943337,0.0013827995,0.00007178875,0.0000033815738,0.000101162026,0.000022890357,0.000038437294,0.9951563,0.0001998063,0.000061552266,0.0025601438],"study_design_scores_gemma":[0.00013622777,0.0019025949,0.02186927,0.000046441768,0.000045239573,0.0015078054,0.00012177199,0.0015752645,0.96553826,0.00035685668,0.00688887,0.0000113095275],"about_ca_topic_score_codex":0.00022657042,"about_ca_topic_score_gemma":0.0002823588,"teacher_disagreement_score":0.0018641914,"about_ca_system_score_codex":0.00010235225,"about_ca_system_score_gemma":0.0001577443,"threshold_uncertainty_score":0.0062363744},"labels":[],"label_agreement":null},{"id":"W2977543492","doi":"10.1172/jci128475","title":"Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Deutschen Multiple Sklerose Gesellschaft; Deutsche Forschungsgemeinschaft; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research","keywords":"Multiple sclerosis; Immune system; Immunology; Monozygotic twin; Medicine; Acquired immune system; Biology; Neuroscience; Genetics","score_opus":0.17458670221909817,"score_gpt":0.36258017312860313,"score_spread":0.18799347090950497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2977543492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9996804,0.000054800264,0.000063453124,0.0000069690786,0.0000031951377,0.0000040761106,0.00002579215,0.0000016725375,0.0001595916],"genre_scores_gemma":[0.9994997,0.00004538128,0.00016839529,0.000014415093,0.000004207243,0.000005785561,0.00007370009,0.000003408312,0.00018503584],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9996897,0.000068521615,0.000035021323,0.000087747365,0.00007787654,0.00004118936],"domain_scores_gemma":[0.99957126,0.00008556334,0.00014309977,0.000043788128,0.000059917864,0.00009633365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018549315,0.0002985283,0.00024242878,0.0009807625,0.00046151146,0.00031207147,0.00016312355,0.00035738997,0.0014640132],"category_scores_gemma":[0.0014777594,0.0002398645,0.00016967895,0.00036733557,0.00025193632,0.000099053024,0.00031788286,0.00030566,0.00016888739],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024369948,0.00017723175,0.772127,0.00007009294,0.0001350188,0.008449656,0.0020092118,0.00009742909,0.2069394,0.0002450902,0.00023946249,0.0070733423],"study_design_scores_gemma":[0.000023626226,0.00039074183,0.9683548,0.000013088119,0.000070251044,0.019302428,0.00045582475,0.00023886685,0.010576389,0.00009030879,0.00047457003,0.000008980032],"about_ca_topic_score_codex":0.001511651,"about_ca_topic_score_gemma":0.0015337777,"teacher_disagreement_score":0.001511651,"about_ca_system_score_codex":0.00018250333,"about_ca_system_score_gemma":0.00012638331,"threshold_uncertainty_score":0.0048975945},"labels":[],"label_agreement":null},{"id":"W2978447867","doi":"10.1172/jci124120","title":"Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Portage College","funders":"NIH Clinical Center; National Institute of Neurological Disorders and Stroke; Cytokinetics; Genentech; Eunice Kennedy Shriver National Institute of Child Health and Human Development; PTC Therapeutics; Ionis Pharmaceuticals; Cure SMA; Biogen; AveXis; Spinal Muscular Atrophy Foundation; Pfizer; Johns Hopkins University","keywords":"Spinal muscular atrophy; SMA*; Medicine; Spinal cord; Motor neuron; Lumbar; Messenger RNA; Internal medicine; Disease; Bioinformatics; Andrology; Biology; Surgery; Gene; Genetics","score_opus":0.11842843359950538,"score_gpt":0.446388309202579,"score_spread":0.3279598756030736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978447867","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9245884,0.06424145,0.0060747364,0.0009373204,0.00012790371,0.00006203177,0.00028255727,0.00008156334,0.0036041257],"genre_scores_gemma":[0.9759184,0.017129041,0.004607815,0.000221665,0.000070096874,0.000063859494,0.00026234027,0.000014106119,0.0017125881],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998522,0.00006317659,0.000015516189,0.000021815074,0.000031838703,0.000015439198],"domain_scores_gemma":[0.9997886,0.000046094134,0.00008860684,0.000012345356,0.000035980334,0.000028482445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005694697,0.00023759337,0.00027644873,0.00018629947,0.00011701025,0.00023827347,0.00016634652,0.00033368412,0.000760709],"category_scores_gemma":[0.00047241946,0.00007778479,0.00016614917,0.000100029276,0.00018047367,0.00020851653,0.00012714847,0.00028795341,0.00018477946],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014176054,0.00013059337,0.032357972,0.00038370606,0.00003278641,0.0005746128,0.00007312362,0.000380499,0.9038904,0.00030959316,0.0004004804,0.06004875],"study_design_scores_gemma":[0.000060547274,0.0067497627,0.5982791,0.00033306782,0.00027071717,0.00404929,0.00040973787,0.0025283238,0.36672643,0.0006615979,0.019898018,0.00003333915],"about_ca_topic_score_codex":0.0003224119,"about_ca_topic_score_gemma":0.000795388,"teacher_disagreement_score":0.000760709,"about_ca_system_score_codex":0.00028554487,"about_ca_system_score_gemma":0.00022190482,"threshold_uncertainty_score":0.003011644},"labels":[],"label_agreement":null},{"id":"W2978687867","doi":"10.1172/jci129187","title":"Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome","year":2019,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":665,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heritage College","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Adipose tissue; White adipose tissue; Adipocyte; Biology; Endocrinology; Adipogenesis; Internal medicine; Adipose tissue macrophages; Hormone; Cell biology; Medicine","score_opus":0.17602838395900394,"score_gpt":0.4257903668924858,"score_spread":0.24976198293348184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978687867","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009445148,0.9991872,0.00006007968,0.00023235937,0.000119077406,0.0000012433528,0.0000052696423,0.000003501879,0.00029692444],"genre_scores_gemma":[0.00076155056,0.99868613,0.00007170785,0.00011563148,0.00015650968,0.000002124394,0.000012126243,6.326476e-7,0.0001935706],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998305,0.000037571237,0.00003129581,0.000031281546,0.000052697807,0.00001656225],"domain_scores_gemma":[0.9997297,0.00013059788,0.00003972457,0.000008012145,0.00006362338,0.000028371573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005849938,0.0007343345,0.0011109023,0.0022317956,0.0002363482,0.00075761304,0.0006288295,0.0010020398,0.0021280372],"category_scores_gemma":[0.00073410396,0.00016650776,0.00037696856,0.0018379346,0.00061621726,0.0008986793,0.0007180746,0.0013953934,0.00094133976],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105256615,0.000059035054,0.0006164185,0.011019412,0.00011000597,0.00044610153,0.000067323905,0.00032204503,0.0012982493,0.0045212866,0.021968417,0.9594664],"study_design_scores_gemma":[0.000027624063,0.00014072943,0.00461067,0.0074485745,0.00023828937,0.006709931,0.00014941733,0.0002165162,0.00063693296,0.0063014044,0.97348344,0.00003641195],"about_ca_topic_score_codex":0.000757712,"about_ca_topic_score_gemma":0.001200616,"teacher_disagreement_score":0.0022317956,"about_ca_system_score_codex":0.0005551269,"about_ca_system_score_gemma":0.00085011317,"threshold_uncertainty_score":0.007119},"labels":[],"label_agreement":null},{"id":"W2981829057","doi":"10.1172/jci130730","title":"Targetable cellular signaling events mediate vascular pathology in vascular Ehlers-Danlos syndrome","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health; Fulbright Chile; National Marfan Foundation; Natural Sciences and Engineering Research Council of Canada; Johns Hopkins University; Howard Hughes Medical Institute","keywords":"Ehlers–Danlos syndrome; Pathology; Medicine; Biology","score_opus":0.04200001237540341,"score_gpt":0.34423535650436377,"score_spread":0.30223534412896036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981829057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896779,0.006280701,0.002037144,0.00024513243,0.000025691656,0.000017690618,0.00010458943,0.00005062522,0.0015603306],"genre_scores_gemma":[0.9966164,0.0021679967,0.00066218356,0.000046858768,0.000010468576,0.000014929717,0.00004857638,0.000003958098,0.0004285723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999925,0.000023550618,0.000008623636,0.000014501299,0.000013905549,0.000014412264],"domain_scores_gemma":[0.99994564,0.00001422738,0.000019112233,0.0000046730615,0.0000031663667,0.000013189459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010112347,0.00038396032,0.000188457,0.00020435019,0.00012104975,0.00022548642,0.0001416605,0.00030924185,0.000699127],"category_scores_gemma":[0.00013016345,0.0001150732,0.00015112491,0.00010407569,0.00038231522,0.00016613507,0.00018933827,0.00050761236,0.00013551187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005544821,0.000065101405,0.0026142332,0.00012691774,0.000022364466,0.0029595601,0.000049603303,0.0002248595,0.98663586,0.00073690456,0.00008738107,0.00592279],"study_design_scores_gemma":[0.000302341,0.001296857,0.06583655,0.000076953234,0.0001457062,0.017960774,0.00025251854,0.0022981586,0.9026637,0.0022595662,0.0068829693,0.000023804967],"about_ca_topic_score_codex":0.0001989711,"about_ca_topic_score_gemma":0.00024829115,"teacher_disagreement_score":0.000699127,"about_ca_system_score_codex":0.00024398888,"about_ca_system_score_gemma":0.00013741123,"threshold_uncertainty_score":0.0023388267},"labels":[],"label_agreement":null},{"id":"W2982382229","doi":"10.1172/jci127341","title":"Effects of maternal iron status on placental and fetal iron homeostasis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"National Institutes of Health; Clinical and Translational Science Institute, University of California, Los Angeles; David Geffen School of Medicine, University of California, Los Angeles; National Institute of Child Health and Human Development; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Magee-Womens Research Institute; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; Robert Wood Johnson Foundation","keywords":"Placenta; Iron deficiency; Fetus; Transferrin receptor; Hepcidin; Ferroportin; Fetal circulation; Trophoblast; Pregnancy; Biology; Transferrin; Physiology; Endocrinology; Internal medicine; Immunology; Medicine; Anemia; Inflammation","score_opus":0.022976220252405987,"score_gpt":0.33182477413775247,"score_spread":0.3088485538853465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982382229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96996427,0.02025972,0.002329233,0.0007350354,0.000058399135,0.000028924642,0.0001942178,0.00006925955,0.006360946],"genre_scores_gemma":[0.9921382,0.0048051206,0.0011967508,0.00017869116,0.000024617588,0.000021979522,0.00008971387,0.000012821887,0.0015321019],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975926,0.000091917675,0.000014132052,0.000036606565,0.00005859472,0.00003943419],"domain_scores_gemma":[0.99971455,0.00009047305,0.00009639811,0.00003018627,0.000025183788,0.000043161843],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004660777,0.00023159741,0.0002928578,0.00030123146,0.00017240825,0.00034123697,0.00016759551,0.00026977094,0.0011186971],"category_scores_gemma":[0.0006629305,0.00014693874,0.00013155787,0.00012896702,0.0003557174,0.00014022877,0.00026399837,0.0004196375,0.00010462596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038074749,0.0001709379,0.037664562,0.00038526885,0.00013121258,0.0027749438,0.0003592589,0.00037212134,0.87859654,0.0020373317,0.0006832285,0.073017046],"study_design_scores_gemma":[0.00014119442,0.003228961,0.43065825,0.00023551275,0.00036423706,0.008009679,0.00047441476,0.002356007,0.5355959,0.0023878245,0.016507605,0.000040444123],"about_ca_topic_score_codex":0.0012411057,"about_ca_topic_score_gemma":0.0010522903,"teacher_disagreement_score":0.0012411057,"about_ca_system_score_codex":0.0005201763,"about_ca_system_score_gemma":0.00022418775,"threshold_uncertainty_score":0.0037741065},"labels":[],"label_agreement":null},{"id":"W2982755374","doi":"10.1172/jci132005","title":"Immune exclusion by naturally acquired secretory IgA against pneumococcal pilus-1","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; U.S. Public Health Service; School of Medicine, New York University; York University","keywords":"Pilus; Microbiology; Biology; Mucus; Streptococcus pneumoniae; Immune system; Immunoglobulin A; Antibody; Colonization; Pathogen; Immunology; Immunoglobulin G; Gene; Escherichia coli; Genetics","score_opus":0.03485130849333248,"score_gpt":0.3464863087446178,"score_spread":0.3116350002512853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982755374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985984,0.00051062804,0.0003122842,0.000033292905,0.0000047287795,0.000008023322,0.000021363638,0.000012088184,0.00049910863],"genre_scores_gemma":[0.9992198,0.00012557703,0.00027823442,0.000035340323,0.0000068837803,0.0000057330494,0.0000404676,0.0000023999191,0.00028552988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978954,0.00007090237,0.0000132545265,0.000030106276,0.00004128566,0.00005498923],"domain_scores_gemma":[0.9998635,0.000038877337,0.000032370663,0.000016892625,0.00001781561,0.000030562147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029624815,0.0002001596,0.00014755102,0.00014518916,0.0001261975,0.00025561205,0.00013238893,0.000217248,0.0009662718],"category_scores_gemma":[0.00046222715,0.00009004739,0.00017832486,0.00004905531,0.00020244672,0.00015508807,0.00023829415,0.00031099629,0.00012240175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046728106,0.00014237675,0.019668981,0.00007073581,0.000017840113,0.00045066822,0.000084859574,0.000051114705,0.96896154,0.00015656321,0.00011946445,0.009808681],"study_design_scores_gemma":[0.00009209379,0.008862315,0.36637706,0.000049600392,0.00007021624,0.0094028115,0.00031169725,0.0019698062,0.60699517,0.0002715793,0.0055824267,0.000015219296],"about_ca_topic_score_codex":0.00023575002,"about_ca_topic_score_gemma":0.00033069457,"teacher_disagreement_score":0.0009662718,"about_ca_system_score_codex":0.00014108016,"about_ca_system_score_gemma":0.00015931365,"threshold_uncertainty_score":0.0032325387},"labels":[],"label_agreement":null},{"id":"W2984584281","doi":"10.1172/jci128469","title":"Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian VIGOUR Centre; University of Alberta","funders":"University of Alberta; Heart and Stroke Foundation of Canada","keywords":"Immune system; Cell biology; Apelin; Biology; Cell injury; Endothelial stem cell; Immunology; Genetics; Receptor; Apoptosis","score_opus":0.03509033401084228,"score_gpt":0.3613508731954672,"score_spread":0.32626053918462494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984584281","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932122,0.0027119757,0.0014673544,0.00008778793,0.000032005293,0.000029355708,0.000054822136,0.0000332521,0.0023712984],"genre_scores_gemma":[0.99530965,0.0016608555,0.0011199154,0.000058977104,0.000039828916,0.000035824956,0.00008705186,0.0000057491116,0.0016822282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998957,0.00003296746,0.000008054882,0.000015329726,0.000022866596,0.000025035773],"domain_scores_gemma":[0.99991536,0.000016196043,0.00001864308,0.000010547977,0.0000075632,0.000031777527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018324774,0.0001537492,0.00016830367,0.00016703825,0.00009932922,0.0002411983,0.00012653465,0.00017800598,0.0008644327],"category_scores_gemma":[0.00024562227,0.000057712652,0.00010010486,0.00009199486,0.00017147686,0.00014847348,0.00020911545,0.0006016552,0.00021361648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007981145,0.00015690079,0.0003776566,0.00009726836,0.00000795775,0.00017877614,0.000037455582,0.00009306974,0.98407537,0.0001548085,0.000088728106,0.013933901],"study_design_scores_gemma":[0.00014290922,0.0049966206,0.023888815,0.000031861095,0.00004487259,0.0008107044,0.00010010391,0.00090635626,0.9633477,0.00022628835,0.005496765,0.0000069666958],"about_ca_topic_score_codex":0.00011886978,"about_ca_topic_score_gemma":0.00021805632,"teacher_disagreement_score":0.0008644327,"about_ca_system_score_codex":0.00011356115,"about_ca_system_score_gemma":0.000116091695,"threshold_uncertainty_score":0.0028918386},"labels":[],"label_agreement":null},{"id":"W2986356453","doi":"10.1172/jci126199","title":"Endogenous T cells prevent tumor immune escape following adoptive T cell therapy","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Government of Ontario; Terry Fox Research Institute; Ontario Institute for Cancer Research","keywords":"Endogeny; Oncolytic virus; Immune system; Adoptive cell transfer; Blockade; Immune checkpoint; Cancer research; Immunology; Antigen; Biology; Cytotoxic T cell; T cell; Tumor antigen; Immunotherapy; Receptor; In vitro","score_opus":0.11018993887874642,"score_gpt":0.3819456765103028,"score_spread":0.27175573763155636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2986356453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97726876,0.003723035,0.015807047,0.0001566523,0.00011847729,0.00017696283,0.000086559405,0.0004063914,0.0022561601],"genre_scores_gemma":[0.9945258,0.0008325302,0.003168707,0.0000711211,0.000049657163,0.00009330843,0.000057950885,0.00001791585,0.0011831168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969435,0.00006330973,0.000023277313,0.00004693647,0.00006422079,0.00010800502],"domain_scores_gemma":[0.99984825,0.00004043467,0.000040910403,0.00003308646,0.000011853819,0.000025488938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026708195,0.00048817045,0.00040318954,0.00027001204,0.000116254974,0.00041169205,0.00030606563,0.00041914915,0.00092483836],"category_scores_gemma":[0.00029914,0.00015005916,0.00021901604,0.000109444074,0.00035575763,0.00026774433,0.0002939314,0.0012832028,0.00025627727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048501318,0.00058484206,0.00044075327,0.0001530773,0.000023580598,0.00013208261,0.000060066966,0.0008558774,0.9777077,0.0013266283,0.0002509071,0.017979562],"study_design_scores_gemma":[0.00026135636,0.005028003,0.0016375529,0.000028096685,0.00007632898,0.0007538172,0.000030259995,0.004944161,0.97988373,0.0005093956,0.0068384167,0.00000910057],"about_ca_topic_score_codex":0.0001438888,"about_ca_topic_score_gemma":0.00026842553,"teacher_disagreement_score":0.00092483836,"about_ca_system_score_codex":0.0001858669,"about_ca_system_score_gemma":0.00029746458,"threshold_uncertainty_score":0.0030938387},"labels":[],"label_agreement":null},{"id":"W2988184724","doi":"10.1172/jci124000","title":"KBTBD13 is an actin-binding protein that modulates muscle kinetics","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Child Health and Human Development; Medical Research Council; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; National Health and Medical Research Council; Horizon 2020 Framework Programme; Office of Science; National Institutes of Health; National Heart, Lung, and Blood Institute; Vetenskapsrådet; Muscular Dystrophy Association; Argonne National Laboratory; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Department of Energy","keywords":"Sarcomere; Actin; Contractility; Muscle relaxation; Nebulin; Biophysics; Nemaline myopathy; Kinetics; Myosin; Cell biology; Myofibril; Muscle contraction; Biology; Chemistry; Myocyte; Endocrinology; Titin","score_opus":0.1433240334916489,"score_gpt":0.38795261475187626,"score_spread":0.24462858126022735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2988184724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9679254,0.007954612,0.01809876,0.00032477756,0.0000805224,0.00007702987,0.0010907233,0.0003039585,0.0041441596],"genre_scores_gemma":[0.983036,0.003772547,0.008586465,0.0001277369,0.00001533373,0.000045793735,0.0009367767,0.00003590263,0.003443459],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999261,0.000005921323,0.00000645721,0.000019923818,0.000030352683,0.0000112249145],"domain_scores_gemma":[0.99992454,0.000012500085,0.000024623578,0.000004502151,0.000014172046,0.000019643183],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012978878,0.00026025614,0.00020543269,0.00023045485,0.0003097541,0.00020591648,0.00029506738,0.0003743441,0.0012196741],"category_scores_gemma":[0.00018431545,0.00016435933,0.00016697632,0.00018168364,0.0002321822,0.0001381227,0.00019838479,0.00030394318,0.00038014518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000867472,0.000017162265,0.0019147708,0.00008631066,0.0000064889064,0.00018727891,0.000017838396,0.0001663826,0.9916324,0.00015987694,0.00014154508,0.005583243],"study_design_scores_gemma":[0.000055617074,0.0004019315,0.0827198,0.00007743495,0.000052598014,0.004249025,0.00009414423,0.004441604,0.8896167,0.00044877134,0.017816218,0.000026266136],"about_ca_topic_score_codex":0.0011087338,"about_ca_topic_score_gemma":0.0013129296,"teacher_disagreement_score":0.0012196741,"about_ca_system_score_codex":0.0003014659,"about_ca_system_score_gemma":0.00014856864,"threshold_uncertainty_score":0.0040801764},"labels":[],"label_agreement":null},{"id":"W2991802127","doi":"10.1172/jci130206","title":"DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto; University Health Network; McGill University Health Centre; University of Calgary; McGill University; Montreal Children's Hospital; McGill University and Génome Québec Innovation Centre; Jewish General Hospital","funders":"Jewish General Hospital; Compute Canada; Banca d'Italia; McGill University; Canadian Institutes of Health Research; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Loss of heterozygosity; Biology; microRNA; Pathology; Genetics; Cancer research; Medicine; Allele; Gene","score_opus":0.035552435803936154,"score_gpt":0.33442134046498045,"score_spread":0.2988689046610443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991802127","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991579,0.0001795853,0.00028293853,0.00001830549,0.0000035232622,0.000005482736,0.00008577228,0.000020714195,0.00024573007],"genre_scores_gemma":[0.9993667,0.00005922937,0.00039568968,0.000012834511,0.0000036826589,0.0000026121634,0.00006327135,0.0000059446074,0.000090021545],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998424,0.000012536231,0.00001932498,0.00005961159,0.000036048077,0.000030138835],"domain_scores_gemma":[0.9996741,0.00007846171,0.00015130008,0.000018751422,0.000020007858,0.000057350077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012437589,0.00054716185,0.0002776678,0.0008103062,0.00023794567,0.00021119574,0.0002460674,0.0004881216,0.0014648269],"category_scores_gemma":[0.0005284033,0.0001353227,0.00018501429,0.000360344,0.00043174383,0.000112592876,0.00030935006,0.00017793674,0.00022799787],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081489526,0.000038935577,0.20957108,0.00013565483,0.000092540584,0.20029119,0.0004664583,0.0003376006,0.5778063,0.0002682005,0.00028981,0.00988729],"study_design_scores_gemma":[0.00004026407,0.00019901096,0.52222,0.000048076723,0.00013997471,0.3953286,0.00031059474,0.0018852955,0.07723258,0.0003519672,0.0022124217,0.000031246822],"about_ca_topic_score_codex":0.000613044,"about_ca_topic_score_gemma":0.0013061471,"teacher_disagreement_score":0.0014648269,"about_ca_system_score_codex":0.00021336856,"about_ca_system_score_gemma":0.00011171017,"threshold_uncertainty_score":0.0049002767},"labels":[],"label_agreement":null},{"id":"W2993062663","doi":"10.1172/jci131145","title":"Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier Universitaire Sainte-Justine; McGill University Health Centre","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; China Scholarship Council; Cancer Research Society; Wellcome Trust; McGill University","keywords":"Histone H4; Neurogenesis; Epigenetics; Neuroscience; Neocortex; Acetylation; Neural stem cell; Biology; Neurosphere; Rett syndrome; Cell biology; Genetics; Cellular differentiation; Stem cell; Gene; Adult stem cell","score_opus":0.04989035214837536,"score_gpt":0.33595471739953575,"score_spread":0.2860643652511604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2993062663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99140584,0.0035525651,0.001483159,0.00028086867,0.000021022142,0.000012589123,0.000436191,0.00010133185,0.002706416],"genre_scores_gemma":[0.99719006,0.0010013004,0.0006896646,0.000035998703,0.000010238947,0.0000067882856,0.00019019462,0.0000078159665,0.0008679312],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999094,0.000013760341,0.000012973414,0.00002365756,0.000023448776,0.000016640568],"domain_scores_gemma":[0.9998895,0.000016183614,0.00006182392,0.000007045799,0.000009357938,0.000015992842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000087076405,0.0005157659,0.00016365653,0.0005228748,0.00023387144,0.00016272462,0.00017139071,0.00035028547,0.0016089488],"category_scores_gemma":[0.00029669984,0.00010940692,0.0001674449,0.00031131285,0.00038261223,0.00012263552,0.00035678165,0.00023828982,0.00016228949],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016964794,0.00011756611,0.23283583,0.0003983128,0.0003153228,0.035686113,0.0004887405,0.00077941915,0.6434571,0.0028738892,0.001480088,0.07987117],"study_design_scores_gemma":[0.00007951306,0.0005358636,0.6957446,0.000121634606,0.00047908464,0.078920625,0.0005156819,0.001606008,0.19829246,0.003314207,0.020352596,0.00003770987],"about_ca_topic_score_codex":0.0012257479,"about_ca_topic_score_gemma":0.0010670633,"teacher_disagreement_score":0.0016089488,"about_ca_system_score_codex":0.00021837027,"about_ca_system_score_gemma":0.00025833526,"threshold_uncertainty_score":0.0053824186},"labels":[],"label_agreement":null},{"id":"W2995637865","doi":"10.1172/jci130819","title":"Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Helminth infection and control","field":"Veterinary","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Terry Fox Foundation; Michael Smith Health Research BC; Prostate Cancer Canada; Prostate Cancer Foundation","keywords":"Ivermectin; Oncogene; Pharmacology; Cancer research; Hsp27; Medicine; Biology; Immunology; Bioinformatics; Heat shock protein; Cancer; Internal medicine; Genetics; Hsp70; Cell cycle; Veterinary medicine; Gene","score_opus":0.10718498204008085,"score_gpt":0.38666637902328954,"score_spread":0.2794813969832087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995637865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945517,0.0011585894,0.001413317,0.00014773973,0.000028929962,0.000057747937,0.00037427715,0.000111422305,0.0021562055],"genre_scores_gemma":[0.99713326,0.00067928864,0.000704505,0.0000475207,0.000005063536,0.000021526956,0.00038258443,0.000011795539,0.001014435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999267,0.000012336774,0.0000033679453,0.000009685776,0.000016859763,0.000031117037],"domain_scores_gemma":[0.99995804,0.0000065458084,0.000010857354,0.0000040652762,0.0000061422725,0.000014262456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001105866,0.00025560352,0.00024122381,0.00019739177,0.00006858429,0.00017515002,0.0002109269,0.00016906638,0.000850637],"category_scores_gemma":[0.00009493318,0.000073808864,0.00021187929,0.0001323011,0.00016729935,0.0001377204,0.000120998615,0.0005099523,0.00013117406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025323185,0.00022357756,0.0001562883,0.000067449866,0.000015746804,0.00003743222,0.000008621579,0.0009104817,0.9940754,0.00010199838,0.00027565262,0.0038740335],"study_design_scores_gemma":[0.000064285625,0.002294122,0.0025440655,0.000010013358,0.00002970736,0.00014378926,0.000015015569,0.0031931573,0.98829925,0.00004838116,0.0033516283,0.0000064629276],"about_ca_topic_score_codex":0.0011078111,"about_ca_topic_score_gemma":0.0022430301,"teacher_disagreement_score":0.0011078111,"about_ca_system_score_codex":0.00033071692,"about_ca_system_score_gemma":0.00017638755,"threshold_uncertainty_score":0.0028457046},"labels":[],"label_agreement":null},{"id":"W2997784912","doi":"10.1172/jci129301","title":"Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":239,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre; Children's Hospital of Eastern Ontario; Dalhousie University; Hospital for Sick Children; Janeway Children's Health and Rehabilitation Centre; Alberta Children's Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; NIH Clinical Center; National Institutes of Health","keywords":"Cytokine; Interferon; Immunology; Medicine; Computational biology; Biology","score_opus":0.042444035500891035,"score_gpt":0.348151730172949,"score_spread":0.30570769467205794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997784912","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99860495,0.0003998453,0.00028820784,0.000021435615,0.000004538874,0.000010413254,0.00008027964,0.0000090859285,0.0005812993],"genre_scores_gemma":[0.99887794,0.00013680631,0.00058358535,0.0000418398,0.00001737038,0.000013371708,0.0002266148,0.000002895792,0.00009959442],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99967146,0.000062504034,0.00005989256,0.00009431503,0.0000468068,0.000064989945],"domain_scores_gemma":[0.99935263,0.00014558849,0.00026153598,0.000044761757,0.00006422468,0.00013131567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004063015,0.0005246946,0.00045053754,0.00075469184,0.00028674988,0.00042376778,0.00016535011,0.0003054459,0.0017657342],"category_scores_gemma":[0.00080965564,0.0001345403,0.00026311813,0.00058500306,0.00035741585,0.00024203984,0.00049023994,0.00027956814,0.0002512246],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055914803,0.00003706174,0.97558695,0.000051113795,0.000038560538,0.0021469174,0.00015124283,0.00007028817,0.012753742,0.00011981922,0.000124371,0.008360823],"study_design_scores_gemma":[0.00006107957,0.00033065886,0.9713372,0.000030197672,0.00007580451,0.023938311,0.00026654018,0.0006011707,0.0024205276,0.00017534847,0.00075366645,0.000009442165],"about_ca_topic_score_codex":0.00030698528,"about_ca_topic_score_gemma":0.00054422236,"teacher_disagreement_score":0.0017657342,"about_ca_system_score_codex":0.00021663161,"about_ca_system_score_gemma":0.00016216807,"threshold_uncertainty_score":0.0059069395},"labels":[],"label_agreement":null},{"id":"W2999376644","doi":"10.1172/jci130363","title":"The glucocorticoid receptor–FKBP51 complex contributes to fear conditioning and posttraumatic stress disorder","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Centre for Addiction and Mental Health","keywords":"Glucocorticoid receptor; Posttraumatic stress; Anxiety; Major depressive disorder; Anxiety disorder; Psychology; Glucocorticoid; Fear conditioning; Internal medicine; Clinical psychology; Medicine; Psychiatry","score_opus":0.13093240032680462,"score_gpt":0.38681645987565694,"score_spread":0.2558840595488523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999376644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890537,0.0059209913,0.0018308009,0.00071561174,0.00007773245,0.000030916413,0.00011801328,0.00004964412,0.0022026119],"genre_scores_gemma":[0.9965598,0.0018816795,0.00036826424,0.00011424435,0.000032873704,0.000009878584,0.00007645188,0.0000041777566,0.00095263025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991465,0.00002175054,0.0000050593158,0.00001373938,0.000020515454,0.00002440668],"domain_scores_gemma":[0.9999149,0.000008720874,0.000033609384,0.00000963841,0.0000074820005,0.000025619342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010505134,0.000266211,0.00017429155,0.00016686013,0.00017671347,0.00017880363,0.000119068536,0.00023032723,0.0013028323],"category_scores_gemma":[0.00017081284,0.00010855664,0.00014677012,0.00010081172,0.0003083951,0.00008287975,0.00020122487,0.00041678702,0.00015149413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002777284,0.0003373975,0.01541753,0.00022286635,0.00011554978,0.0011038827,0.00010798367,0.00036764654,0.9362641,0.0014191465,0.0011206813,0.040745962],"study_design_scores_gemma":[0.00021379667,0.0017411892,0.7915324,0.000080576785,0.0003168198,0.004715299,0.00022394677,0.002381222,0.18187197,0.0023039307,0.014579654,0.000039191906],"about_ca_topic_score_codex":0.0010887505,"about_ca_topic_score_gemma":0.00085413276,"teacher_disagreement_score":0.0013028323,"about_ca_system_score_codex":0.00026087573,"about_ca_system_score_gemma":0.00020070771,"threshold_uncertainty_score":0.004358411},"labels":[],"label_agreement":null},{"id":"W2999811208","doi":"10.1172/jci128459","title":"Capsular glycan recognition provides antibody-mediated immunity against tuberculosis","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"National Center for Advancing Translational Sciences; Alberta Glycomics Centre; Canadian Glycomics Network; National Institutes of Health; National Cancer Institute; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Tuberculosis; Mycobacterium tuberculosis; Immunology; Glycan; Epitope; Antigen; Antibody; Immune system; Vaccination; Immunity; Latent tuberculosis; Tuberculosis vaccines; Biology; Virology; Medicine; Microbiology","score_opus":0.16370791324592396,"score_gpt":0.42565135722316594,"score_spread":0.261943443977242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999811208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98820215,0.0053467336,0.0027371347,0.00026856657,0.000023473174,0.000027013773,0.00010932454,0.000045517565,0.0032400456],"genre_scores_gemma":[0.9976018,0.0011040948,0.00089022296,0.00010035052,0.00002289692,0.0000042595534,0.00005481545,0.0000025262498,0.00021898781],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999833,0.00006455966,0.000008702879,0.00002581501,0.00003215547,0.000035776666],"domain_scores_gemma":[0.9998894,0.00003071262,0.000030969863,0.00001105061,0.00001739792,0.00002047069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002905121,0.00019536541,0.00012115275,0.00018091369,0.00008798721,0.0003053431,0.00011444114,0.00025587247,0.0011668269],"category_scores_gemma":[0.0005700676,0.00009252589,0.000098378005,0.00013593091,0.0001654531,0.0001991763,0.00024822654,0.00024997647,0.00020541486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066046533,0.00015759222,0.08353239,0.0003153623,0.00008277445,0.00036199385,0.00019016974,0.0004698454,0.83911604,0.000665448,0.0005046208,0.07394326],"study_design_scores_gemma":[0.00008285413,0.0024650767,0.7597622,0.00011736346,0.00017705189,0.0042561195,0.00035790322,0.0035730335,0.20860136,0.0017201477,0.01885973,0.000026992102],"about_ca_topic_score_codex":0.00059368694,"about_ca_topic_score_gemma":0.0004900731,"teacher_disagreement_score":0.0011668269,"about_ca_system_score_codex":0.00015132796,"about_ca_system_score_gemma":0.00017551615,"threshold_uncertainty_score":0.003903389},"labels":[],"label_agreement":null},{"id":"W3003004415","doi":"10.1172/jci99934","title":"Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Heart and Stroke Foundation; University Health Network; Toronto General Hospital; University of Toronto; Ted Rogers Centre for Heart Research","funders":"Canadian Institutes of Health Research; Novo Nordisk; University of Toronto; Toronto General Hospital Research Institute, University Health Network; Heart and Stroke Foundation of Canada","keywords":"Glycolysis; Chemistry; Glucagon-like peptide-1; Biochemistry; Internal medicine; Pharmacology; Endocrinology; Cell biology; Biology; Metabolism; Medicine","score_opus":0.045910617349171255,"score_gpt":0.3288346081097357,"score_spread":0.28292399076056446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003004415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946408,0.0015047924,0.002810794,0.0001381093,0.000033551984,0.000033818873,0.00015727589,0.0000632793,0.0006174754],"genre_scores_gemma":[0.9942761,0.0013123404,0.0030798148,0.00006727671,0.000031924894,0.000050362276,0.00030943836,0.000010491771,0.00086227275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999367,0.000012508202,0.0000059318077,0.000014021755,0.000011602337,0.00001918957],"domain_scores_gemma":[0.999944,0.000006611289,0.000022763063,0.00000563701,0.00000565964,0.00001534745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012906519,0.00033972468,0.00031252642,0.00010369292,0.00011476134,0.00017145413,0.00013942187,0.00020236624,0.0007626466],"category_scores_gemma":[0.0000760166,0.00007215436,0.00024390769,0.00005594998,0.00016859199,0.00017814846,0.000121526464,0.0007090323,0.00018181086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026499535,0.0000380401,0.00008103806,0.000030727766,0.0000045790453,0.000030126193,0.0000072133635,0.0000344047,0.99812657,0.000044008226,0.00002299457,0.0013153981],"study_design_scores_gemma":[0.000052051662,0.0011203397,0.0025522485,0.0000057845605,0.000016553655,0.00027577166,0.00001801529,0.0005555591,0.99403256,0.0000322941,0.0013358963,0.0000029524533],"about_ca_topic_score_codex":0.0001419527,"about_ca_topic_score_gemma":0.00020873356,"teacher_disagreement_score":0.0007626466,"about_ca_system_score_codex":0.00013560183,"about_ca_system_score_gemma":0.00012713393,"threshold_uncertainty_score":0.0025513172},"labels":[],"label_agreement":null},{"id":"W3003611811","doi":"10.1172/jci131700","title":"Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":187,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Institute of Infection and Immunity","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Cytotoxic T cell; Immunology; CD8; Fibrosis; Apoptosis; Immune system; Biology; T cell; Pathogenesis; Scleroderma (fungus); Medicine; Cancer research; Pathology; In vitro","score_opus":0.1309557769457165,"score_gpt":0.3386674251786355,"score_spread":0.20771164823291902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003611811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984933,0.0005864565,0.0003818987,0.000015754582,0.000002394431,0.0000040608547,0.000009433022,0.00001297475,0.00049376086],"genre_scores_gemma":[0.99945384,0.00009945171,0.0001538817,0.000014689258,0.000004321778,0.0000036995818,0.000017962418,0.0000013984856,0.0002507707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998882,0.000037245325,0.000008696838,0.000018441573,0.000024604513,0.00002286217],"domain_scores_gemma":[0.9998568,0.000045116692,0.000029293946,0.000020166486,0.0000269364,0.000021555079],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022159674,0.0001226658,0.00014618658,0.000324985,0.00013693342,0.00020708641,0.00006455243,0.00018372973,0.001065259],"category_scores_gemma":[0.00031826555,0.00007731867,0.00009654551,0.00014903034,0.00022032553,0.00011921214,0.00011648389,0.00021375544,0.00011378162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014865949,0.00015564359,0.13577998,0.00016180205,0.00005783001,0.0020977848,0.0002820062,0.00063182146,0.8197604,0.00031687884,0.00016168729,0.03910757],"study_design_scores_gemma":[0.00036742334,0.0036547382,0.6646865,0.000048624297,0.00017067067,0.015004957,0.00041750504,0.0037684978,0.30659744,0.0011757154,0.004090077,0.00001785805],"about_ca_topic_score_codex":0.00021617107,"about_ca_topic_score_gemma":0.00025725257,"teacher_disagreement_score":0.001065259,"about_ca_system_score_codex":0.0001365101,"about_ca_system_score_gemma":0.00007112974,"threshold_uncertainty_score":0.0035636425},"labels":[],"label_agreement":null},{"id":"W3004522818","doi":"10.1172/jci131048","title":"Chronic mTOR activation induces a degradative smooth muscle cell phenotype","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Natural Science Foundation of China; National Center for Advancing Translational Sciences; Yale University","keywords":"Phenotype; PI3K/AKT/mTOR pathway; Cell biology; Cell; Cell growth; Cancer research; Chemistry; Medicine; Biology; Signal transduction; Biochemistry; Gene","score_opus":0.08338730667937345,"score_gpt":0.35086320123678755,"score_spread":0.2674758945574141,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004522818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965522,0.0010809029,0.00082220486,0.00007121683,0.00002603641,0.00002439772,0.00018527675,0.00006531834,0.001172469],"genre_scores_gemma":[0.99678254,0.00064114825,0.00083261926,0.000051819858,0.000012986694,0.000035467896,0.0002947642,0.00000929874,0.0013392677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998554,0.000029750961,0.000015461495,0.000027670712,0.00003357999,0.000038000344],"domain_scores_gemma":[0.99988973,0.0000175923,0.000034912806,0.00001569833,0.000009463257,0.000032660144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016441841,0.0002779133,0.0002545898,0.00025686165,0.00017594006,0.0002474961,0.00009256569,0.00022782836,0.000995129],"category_scores_gemma":[0.0000900164,0.00014506571,0.00017004921,0.00013355493,0.00028306473,0.000096697535,0.00022667869,0.0004829637,0.00024677528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012978238,0.000039380775,0.00026611538,0.000023683275,0.0000037408577,0.000058825444,0.000009812219,0.000021814685,0.998466,0.000082823964,0.000035298344,0.00086276454],"study_design_scores_gemma":[0.000046019104,0.0016427564,0.01704365,0.000011389377,0.000028561244,0.00077834004,0.000059222388,0.00079688826,0.97621495,0.000091222515,0.0032799668,0.000007094359],"about_ca_topic_score_codex":0.0003078569,"about_ca_topic_score_gemma":0.0008804431,"teacher_disagreement_score":0.000995129,"about_ca_system_score_codex":0.00019927525,"about_ca_system_score_gemma":0.00019831842,"threshold_uncertainty_score":0.0033290386},"labels":[],"label_agreement":null},{"id":"W3004775388","doi":"10.1172/jci132374","title":"BCL-2 antagonism sensitizes cytotoxic T cell–resistant HIV reservoirs to elimination ex vivo","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Maple Leaf Medical Clinic","funders":"College of Veterinary Medicine, Cornell University; National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Institute on Drug Abuse; National Institute of Mental Health; Fogarty International Center; National Heart, Lung, and Blood Institute; Center for AIDS Research, University of Washington; Office of AIDS Research; National Institute on Aging; National Cancer Institute; National Institutes of Health","keywords":"CTL*; Ex vivo; Cytotoxic T cell; Biology; Immunology; In vivo; Immunotherapy; Cancer research; T cell; Virology; CD8; Immune system; In vitro; Genetics","score_opus":0.0771924329056798,"score_gpt":0.3522961637039018,"score_spread":0.27510373079822203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004775388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971609,0.00045893347,0.0009902848,0.000086094515,0.000023930668,0.000028974922,0.00007351445,0.000058715224,0.0011186451],"genre_scores_gemma":[0.99734616,0.00037081176,0.00096756336,0.00004677164,0.000020429687,0.000024923354,0.00014215242,0.000010458231,0.0010705875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987245,0.000033250737,0.000009282114,0.000016109334,0.000027862825,0.000040962575],"domain_scores_gemma":[0.9999076,0.000032454907,0.000013696348,0.000015828711,0.0000056117838,0.000024726842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015862894,0.00028090188,0.00033241723,0.0001428407,0.00013398877,0.00045444304,0.00020022699,0.00018486562,0.0016894041],"category_scores_gemma":[0.00013534994,0.000116529336,0.00012646252,0.000088710316,0.000197372,0.00022063666,0.00015937154,0.00096965313,0.00029789028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015959621,0.00022721429,0.00020169177,0.000020684813,0.000005327601,0.000026382379,0.000012491425,0.00011158264,0.99638844,0.00009566978,0.00005383473,0.0026970713],"study_design_scores_gemma":[0.00007577634,0.0025654775,0.0022012482,0.0000043650543,0.00001762766,0.00030745607,0.000019865598,0.0014180308,0.99149996,0.000090421745,0.0017954641,0.000004446692],"about_ca_topic_score_codex":0.00013649579,"about_ca_topic_score_gemma":0.0004845326,"teacher_disagreement_score":0.0016894041,"about_ca_system_score_codex":0.0001506803,"about_ca_system_score_gemma":0.0001724477,"threshold_uncertainty_score":0.005651593},"labels":[],"label_agreement":null},{"id":"W3004964052","doi":"10.1172/jci134402","title":"Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":200,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Rogel Cancer Center, University of Michigan; National Cancer Institute; National Institutes of Health; College of Pharmacy, University of Michigan; Ovarian Cancer Research Alliance; National Institute of Allergy and Infectious Diseases; National Cancer Center; University of Michigan","keywords":"ARID1A; Epigenetics; Biology; Cancer research; Immune system; Cancer; Immunotherapy; Chromatin; Cancer immunotherapy; EZH2; Phenotype; Immunology; Cancer cell; Gene; Mutation; Genetics","score_opus":0.05520385444857682,"score_gpt":0.3615813248961588,"score_spread":0.30637747044758196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004964052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931397,0.0015080861,0.001530215,0.00024212443,0.000016488671,0.000013644376,0.00026423373,0.000058117454,0.0032275068],"genre_scores_gemma":[0.99878365,0.0002897082,0.00030271852,0.000046096393,0.0000050922918,0.0000043831783,0.000060767507,0.0000056934778,0.00050184474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998977,0.000023138085,0.0000084242665,0.000021165399,0.0000301328,0.000019307348],"domain_scores_gemma":[0.999894,0.00002061285,0.00004385736,0.000009365105,0.000009560741,0.000022608325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001856818,0.00013221685,0.00013161382,0.00018205441,0.00009650095,0.0003406217,0.00012507795,0.00024944765,0.0015069785],"category_scores_gemma":[0.00029594355,0.00011070742,0.00009441696,0.00011100466,0.0002570692,0.00020473557,0.00017365107,0.00028283705,0.00031701577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049769675,0.000047773578,0.03391531,0.00005371758,0.000031546337,0.00044135982,0.000057014568,0.00076548575,0.9468964,0.0015341247,0.00043730746,0.015322363],"study_design_scores_gemma":[0.000093820425,0.00081676757,0.3346921,0.000035545414,0.0001041029,0.009057756,0.0004588551,0.009746654,0.6230906,0.0037398036,0.018127047,0.000036923262],"about_ca_topic_score_codex":0.00013202347,"about_ca_topic_score_gemma":0.0002504844,"teacher_disagreement_score":0.0015069785,"about_ca_system_score_codex":0.00026013757,"about_ca_system_score_gemma":0.00014307229,"threshold_uncertainty_score":0.005041361},"labels":[],"label_agreement":null},{"id":"W3006103160","doi":"10.1172/jci134066","title":"Distinct immune characteristics distinguish hereditary and idiopathic chronic pancreatitis","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Pancreas Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; University of Minnesota; Howard Hughes Medical Institute","keywords":"Immune system; Pancreatitis; Immunology; T-cell receptor; Pathogenesis; Acquired immune system; Biology; Repertoire; Immunophenotyping; Innate immune system; T cell; Medicine; Antigen; Internal medicine","score_opus":0.05965749475583453,"score_gpt":0.34174498156788086,"score_spread":0.2820874868120463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006103160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99916005,0.00036102688,0.00013491881,0.0000062627487,0.0000018325068,0.000004162114,0.000027363692,0.0000028759737,0.0003015743],"genre_scores_gemma":[0.9994005,0.00019489162,0.00020428715,0.000014177998,0.000008320075,0.0000062432023,0.000082673476,0.000002271062,0.00008656474],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99983346,0.00003604927,0.000021891528,0.000040035364,0.000030878717,0.000037602425],"domain_scores_gemma":[0.9996779,0.000100175814,0.00011027772,0.000026235153,0.000025177364,0.000060351067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002394911,0.00018936138,0.00020974268,0.0008863964,0.00015003842,0.00027112282,0.00009184427,0.00024343075,0.001331502],"category_scores_gemma":[0.0006895507,0.00007523092,0.0001200103,0.00041229944,0.00028610733,0.00019906428,0.0002719637,0.00015144805,0.000113137896],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001775657,0.00013299221,0.7714218,0.00013719106,0.000048924074,0.003505589,0.00058178225,0.00008757439,0.20265694,0.00029314734,0.000102891085,0.01925557],"study_design_scores_gemma":[0.000019722236,0.00056085055,0.9802537,0.00001862268,0.000026722893,0.011558903,0.00040784696,0.00020416622,0.006100055,0.0001540954,0.00069034565,0.0000050700187],"about_ca_topic_score_codex":0.00015969205,"about_ca_topic_score_gemma":0.0002279935,"teacher_disagreement_score":0.001331502,"about_ca_system_score_codex":0.00010561542,"about_ca_system_score_gemma":0.00008996533,"threshold_uncertainty_score":0.0044543147},"labels":[],"label_agreement":null},{"id":"W3007256318","doi":"10.1172/jci133572","title":"Muscle-derived interleukin 6 increases exercise capacity by signaling in osteoblasts","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Exercise and Physiological Responses","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; Institut de Recherche Clinique De Montréal; Yale University; Ministerio de Economía y Competitividad; National Institute of Immunology; National Institute on Aging; European Regional Development Fund; TrygFonden","keywords":"Osteocalcin; Endocrinology; Internal medicine; Crosstalk; Physical exercise; Catabolism; Bone remodeling; Receptor; Medicine; Chemistry; Alkaline phosphatase; Biochemistry; Metabolism","score_opus":0.12384410159376319,"score_gpt":0.3658566209451041,"score_spread":0.24201251935134094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3007256318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98551685,0.0056500253,0.003946191,0.0006040955,0.00010924822,0.000038960374,0.0002144849,0.000079753714,0.0038404453],"genre_scores_gemma":[0.9918148,0.002934958,0.0027887765,0.00014712577,0.000068039706,0.00003303201,0.00012978728,0.000016215638,0.0020673429],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998827,0.000023740822,0.000008273912,0.000015936126,0.000042146294,0.000027195945],"domain_scores_gemma":[0.99991107,0.0000147748,0.000024701754,0.0000068822196,0.000008493706,0.000034146433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001752317,0.0002105052,0.00019365804,0.00019140722,0.00009863039,0.0002722753,0.00011423735,0.00022654471,0.0014362513],"category_scores_gemma":[0.00020411205,0.000113676644,0.00020861837,0.00008526239,0.00025367126,0.00014905422,0.00034709094,0.00059163844,0.00031104314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042905222,0.00009462285,0.0008104358,0.00007944423,0.0000062952176,0.0001134802,0.000031317875,0.00005761887,0.9920582,0.00014592172,0.00006793281,0.0061057],"study_design_scores_gemma":[0.00034770774,0.0038888725,0.099667765,0.00008174047,0.000083415165,0.0013189425,0.00031060266,0.0014642436,0.8796605,0.0012808312,0.011875274,0.00002018901],"about_ca_topic_score_codex":0.00012670695,"about_ca_topic_score_gemma":0.0003239398,"teacher_disagreement_score":0.0014362513,"about_ca_system_score_codex":0.000081802544,"about_ca_system_score_gemma":0.00015066491,"threshold_uncertainty_score":0.00480479},"labels":[],"label_agreement":null},{"id":"W3007590143","doi":"10.1172/jci131254","title":"Protein arginine methyltransferase 5 promotes cholesterol biosynthesis–mediated Th17 responses and autoimmunity","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Research Institute, Nationwide Children's Hospital; National Cancer Institute; National Institutes of Health; Nationwide Children's Hospital; Pelotonia; Ohio State University","keywords":"Protein arginine methyltransferase 5; Experimental autoimmune encephalomyelitis; RAR-related orphan receptor gamma; Orphan receptor; Arginine; Cell biology; Biology; Chemistry; Methyltransferase; Biochemistry; Immunology; Immune system; Methylation; FOXP3; Transcription factor; Amino acid","score_opus":0.06269572043454023,"score_gpt":0.33798130922495645,"score_spread":0.2752855887904162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3007590143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99135125,0.003830576,0.0019709861,0.00017689067,0.000050760027,0.000024942547,0.00012801134,0.000106470914,0.0023601206],"genre_scores_gemma":[0.9965777,0.0007238742,0.00070043525,0.00003941343,0.000013443061,0.0000090945905,0.00009067938,0.000007708871,0.0018377212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997873,0.000049753948,0.000018285222,0.00003464027,0.00004945323,0.000060662707],"domain_scores_gemma":[0.99988246,0.0000101242085,0.000042203235,0.000012354241,0.000011904956,0.000040902712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021134682,0.00025514283,0.00018764618,0.00028835755,0.00016287704,0.000323205,0.000114945535,0.00024672848,0.0016609541],"category_scores_gemma":[0.00013016693,0.00011044381,0.00023845735,0.00014534235,0.00025522485,0.00014347163,0.0002357916,0.00053994544,0.00035744757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002702396,0.000036211353,0.0008236861,0.00004200638,0.000005450136,0.00008183999,0.000019858959,0.000044968474,0.9957949,0.00012925606,0.000046238896,0.002705266],"study_design_scores_gemma":[0.000062756495,0.00093807955,0.024720008,0.00001883731,0.000041756786,0.000608455,0.000079893325,0.0008788506,0.96526504,0.00017802461,0.007201143,0.0000071442],"about_ca_topic_score_codex":0.00038037138,"about_ca_topic_score_gemma":0.0007676946,"teacher_disagreement_score":0.0016609541,"about_ca_system_score_codex":0.00024941794,"about_ca_system_score_gemma":0.00027031984,"threshold_uncertainty_score":0.0055564046},"labels":[],"label_agreement":null},{"id":"W3009853057","doi":"10.1172/jci130670","title":"Ubiquitous antigen-specific T regulatory type 1 cells variably suppress hepatic and extrahepatic autoimmunity","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Crohn's and Colitis Foundation of Canada; Diabetes Canada; Multiple Sclerosis Society of Canada; Crohn's and Colitis Foundation","keywords":"Autoimmunity; Experimental autoimmune encephalomyelitis; Immunology; Biology; Antigen; Autoimmune disease; Central tolerance; Epitope; Inflammation; Immune system; Antibody","score_opus":0.07243072320524774,"score_gpt":0.30803975876400697,"score_spread":0.23560903555875923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3009853057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986759,0.0042113257,0.005206049,0.00009517944,0.00009013979,0.00003922765,0.00012603252,0.0002547846,0.0032182152],"genre_scores_gemma":[0.9935129,0.0013052057,0.001988322,0.00009656584,0.000039029153,0.000043830758,0.0001664824,0.000029783958,0.002817824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998324,0.000029387136,0.00001442564,0.000036616435,0.00003901243,0.00004822807],"domain_scores_gemma":[0.9999126,0.000015077283,0.000022944552,0.00001859929,0.000008755672,0.000022108363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013105241,0.00030674538,0.00024517116,0.00014376084,0.000065614135,0.00018410501,0.00014796751,0.00023575922,0.0007719098],"category_scores_gemma":[0.00012571564,0.000080271355,0.00014314557,0.00010640248,0.00014311256,0.00014498441,0.00013034503,0.0005976756,0.00024252124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016228593,0.00008310044,0.00013613449,0.00005508751,0.0000053152417,0.00003577035,0.000012754456,0.000090309695,0.9919906,0.00010996335,0.000075714706,0.0072430023],"study_design_scores_gemma":[0.00006008573,0.001937296,0.0026263937,0.000009156786,0.000037265727,0.00048152317,0.000024056546,0.000784394,0.98829585,0.00009343299,0.0056457734,0.0000048114152],"about_ca_topic_score_codex":0.00009686688,"about_ca_topic_score_gemma":0.00019785964,"teacher_disagreement_score":0.0007719098,"about_ca_system_score_codex":0.00008237351,"about_ca_system_score_gemma":0.00014476558,"threshold_uncertainty_score":0.0025823116},"labels":[],"label_agreement":null},{"id":"W3010473572","doi":"10.1172/jci130426","title":"IRF4 instructs effector Treg differentiation and immune suppression in human cancer","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":203,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Medical Research Council; Bristol-Myers Squibb Canada; Associazione Italiana per la Ricerca sul Cancro; Fondazione Umberto Veronesi; University of Melbourne; Biotechnology and Biological Sciences Research Council; Ministero della Salute; Bristol-Myers Squibb; Deutsche Forschungsgemeinschaft; Cancer Research UK","keywords":"IRF4; Biology; Effector; Cancer research; Immunosuppression; Immune system; Immunology; Transcription factor; Tumor microenvironment; Gene; Genetics","score_opus":0.05644923121328204,"score_gpt":0.3473673667599879,"score_spread":0.29091813554670587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010473572","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953833,0.002359295,0.00082336686,0.00006664484,0.000011865661,0.000013739594,0.00011938721,0.00006478403,0.0011575798],"genre_scores_gemma":[0.99804246,0.0007001495,0.0005027974,0.000034898192,0.000006984672,0.000009838842,0.00018170336,0.0000074279296,0.0005136955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999089,0.000020693837,0.0000044997073,0.000012701748,0.000016128508,0.000037023518],"domain_scores_gemma":[0.99995625,0.000009518384,0.000010191082,0.000007995746,0.000006052002,0.000009986804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016979629,0.00015111093,0.0002141514,0.0003230747,0.00017989863,0.0002352123,0.000103233455,0.00017806234,0.0010361316],"category_scores_gemma":[0.0001657743,0.00009828939,0.00015994228,0.00018582934,0.00015901437,0.00010378195,0.00017581346,0.00027635807,0.00030091972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006177196,0.000099691235,0.0069469116,0.00006594802,0.000010711277,0.0002512792,0.0000493731,0.00025507476,0.9762991,0.00027637818,0.0002507148,0.0148770455],"study_design_scores_gemma":[0.00009507783,0.0013855019,0.124579735,0.000038763756,0.00008669725,0.0033993153,0.00026196163,0.0028592213,0.85017955,0.0011055059,0.015989259,0.000019466172],"about_ca_topic_score_codex":0.00040208214,"about_ca_topic_score_gemma":0.00050831126,"teacher_disagreement_score":0.0010361316,"about_ca_system_score_codex":0.00023392118,"about_ca_system_score_gemma":0.00025644273,"threshold_uncertainty_score":0.0034662485},"labels":[],"label_agreement":null},{"id":"W3010667353","doi":"10.1172/jci125898","title":"Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto; Krembil Foundation","funders":"National Institutes of Health; Krembil Foundation; University of Toronto; Foundation Fighting Blindness; Fondation Brain Canada; Research to Prevent Blindness; Cleveland Clinic Foundation; National Eye Institute; Cleveland Clinic","keywords":"Retinal degeneration; Degeneration (medical); Neutralization; Retinal; Retina; Biology; Cell biology; Ophthalmology; Anatomy; Chemistry; Neuroscience; Medicine; Genetics; Antibody","score_opus":0.057062146465381124,"score_gpt":0.34039403007917235,"score_spread":0.28333188361379125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010667353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99690264,0.0010778232,0.0006969028,0.000061788196,0.000025246778,0.000025347574,0.000113763876,0.00007061954,0.0010259192],"genre_scores_gemma":[0.9965154,0.00062265724,0.00086422585,0.000044963217,0.0000067754945,0.000020161582,0.00016574922,0.0000124300295,0.0017476856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992263,0.000014146498,0.000008455328,0.000014855066,0.00001910862,0.000020803029],"domain_scores_gemma":[0.99991906,0.000012089762,0.000021693008,0.000007582178,0.000006671089,0.000032906126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010480279,0.00028274537,0.00021301284,0.00020088057,0.00010119158,0.00016613587,0.00019129847,0.00031247785,0.0010052372],"category_scores_gemma":[0.000092034075,0.000098847806,0.00012638525,0.00007271025,0.00021839193,0.000107784166,0.00012798817,0.0005316082,0.00017407497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023664533,0.00009838744,0.00009574922,0.000030618354,0.000004225693,0.000060352355,0.000009765918,0.000039996863,0.9976544,0.000071263785,0.000033709723,0.00166478],"study_design_scores_gemma":[0.00009167724,0.0022526493,0.005505925,0.000012819666,0.000017024668,0.00044518165,0.000034240264,0.0007045026,0.98927957,0.000071198134,0.00158053,0.0000048214615],"about_ca_topic_score_codex":0.0004009232,"about_ca_topic_score_gemma":0.0007743853,"teacher_disagreement_score":0.0010052372,"about_ca_system_score_codex":0.00017179434,"about_ca_system_score_gemma":0.00020206334,"threshold_uncertainty_score":0.0033628345},"labels":[],"label_agreement":null},{"id":"W3010937093","doi":"10.1172/jci134395","title":"Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Chulalongkorn University; Henry M. Jackson Foundation; U.S. Department of Health and Human Services; U.S. Department of Defense","keywords":"Viremia; Neutralization; Virology; Antibody; Neutralizing antibody; Medicine; Immunology; Human immunodeficiency virus (HIV)","score_opus":0.11121611236104367,"score_gpt":0.42252946247779116,"score_spread":0.3113133501167475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010937093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998478,0.00032518085,0.00059501553,0.000023557906,0.000008950172,0.000024810028,0.000049949056,0.000019620154,0.00047494634],"genre_scores_gemma":[0.9991033,0.00006498672,0.00029693038,0.000043353204,0.0000047735507,0.000013202563,0.00006958028,0.000008007569,0.00039591678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996551,0.00006985188,0.000022664266,0.00007663743,0.00009606475,0.00007969313],"domain_scores_gemma":[0.99932826,0.00024300966,0.00014856952,0.00010786862,0.00010074108,0.000071580085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044357855,0.00020941734,0.0004252805,0.00008258374,0.00016852912,0.00043607783,0.0002546039,0.00030110744,0.0011843509],"category_scores_gemma":[0.0011121448,0.00011824845,0.000156312,0.00008489034,0.0002129653,0.00019091053,0.00011295399,0.00064805045,0.00018300781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028061646,0.00070310547,0.07757294,0.0001434692,0.00013010044,0.000610401,0.0004922587,0.0005874867,0.8477336,0.00022323111,0.0003721349,0.06862509],"study_design_scores_gemma":[0.00032128626,0.035411973,0.4092626,0.00006356892,0.00033012242,0.008400558,0.00038990183,0.0047118166,0.53291315,0.0003569757,0.007791562,0.000046451234],"about_ca_topic_score_codex":0.001181664,"about_ca_topic_score_gemma":0.001260469,"teacher_disagreement_score":0.0011843509,"about_ca_system_score_codex":0.00024221852,"about_ca_system_score_gemma":0.00020893112,"threshold_uncertainty_score":0.00396204},"labels":[],"label_agreement":null},{"id":"W3011150630","doi":"10.1172/jci99027","title":"Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Australian Research Council; South Australian Health and Medical Research Institute; National Health and Medical Research Council; Hospital Research Foundation","keywords":"Lymphangiogenesis; Cell biology; Biology; Lymphatic system; Cadherin; Lymphatic Endothelium; Morphogenesis; Cell polarity; Cancer research; Genetics; Immunology; Gene; Cell","score_opus":0.1171577840787237,"score_gpt":0.3833769492531584,"score_spread":0.2662191651744347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011150630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99329424,0.0011565227,0.0026041772,0.000107264554,0.000016860951,0.00001775753,0.00009188255,0.000065088905,0.0026461862],"genre_scores_gemma":[0.99742436,0.0003666062,0.0008370798,0.00002507695,0.000005565,0.0000088410325,0.000070761555,0.000004687733,0.0012569753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989617,0.000023903716,0.000005445314,0.000010925962,0.000027290573,0.000036194288],"domain_scores_gemma":[0.99992526,0.000012109558,0.000017255148,0.000006117688,0.000016519143,0.000022655026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013208555,0.00017164125,0.00012905794,0.0003641491,0.00017505586,0.00030991802,0.00018300135,0.0002270215,0.0007899921],"category_scores_gemma":[0.00021864467,0.00008428553,0.0000708303,0.00014721249,0.0003775776,0.0002299178,0.00032483635,0.0002092018,0.0001568818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034193503,0.000032240303,0.006797671,0.000058865582,0.000008568384,0.0008763208,0.000064163316,0.0003444028,0.9829556,0.0013943028,0.00024772607,0.0068782624],"study_design_scores_gemma":[0.00010909132,0.00034502256,0.1136235,0.000027130774,0.00003760511,0.0043230746,0.0004134973,0.009726153,0.8552697,0.0014591623,0.014645967,0.000020073587],"about_ca_topic_score_codex":0.00076265103,"about_ca_topic_score_gemma":0.00090023177,"teacher_disagreement_score":0.0007899921,"about_ca_system_score_codex":0.0003631553,"about_ca_system_score_gemma":0.00021093455,"threshold_uncertainty_score":0.0026428103},"labels":[],"label_agreement":null},{"id":"W3011416804","doi":"10.1172/jci128994","title":"Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and Wnt","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Princess Margaret Cancer Centre; Hospital for Sick Children; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Cancer Research Society; Genome Canada","keywords":"Wnt signaling pathway; Carcinogenesis; Notch signaling pathway; Cancer research; Cancer stem cell; Biology; Stem cell; Signal transduction; Cancer; Cell biology; Genetics","score_opus":0.022860467830436104,"score_gpt":0.30345965150840903,"score_spread":0.28059918367797293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011416804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951697,0.0020742114,0.0008570769,0.000059924292,0.0000075999415,0.000015795486,0.00021035496,0.000026838447,0.0015784198],"genre_scores_gemma":[0.9967781,0.0009603163,0.0004923343,0.000032400505,0.0000036095169,0.000015316962,0.00024348329,0.0000037186867,0.0014708561],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999155,0.000015763393,0.0000090947815,0.000010635869,0.00002454596,0.000024494235],"domain_scores_gemma":[0.9999634,0.0000032668206,0.000009441471,0.0000038910507,0.0000039694446,0.000016124388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010271754,0.00020897454,0.00017130101,0.00019721848,0.00009304766,0.0002913809,0.00012610584,0.00012739337,0.00047712514],"category_scores_gemma":[0.00006343442,0.000071382245,0.00014540488,0.00009929901,0.00011644458,0.000144815,0.00021409955,0.00023711789,0.00014609711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021712978,0.000024758046,0.00082106714,0.00005447885,0.000006591051,0.00010854176,0.000019543302,0.00010007835,0.9956897,0.00036583235,0.000047435842,0.0025447507],"study_design_scores_gemma":[0.000038561666,0.00033253885,0.040785655,0.000014175143,0.000052481635,0.00055916386,0.00008094879,0.002265806,0.9497599,0.00017356845,0.0059285085,0.000008569238],"about_ca_topic_score_codex":0.0008510716,"about_ca_topic_score_gemma":0.0017018337,"teacher_disagreement_score":0.0008510716,"about_ca_system_score_codex":0.00038580384,"about_ca_system_score_gemma":0.00017598017,"threshold_uncertainty_score":0.002799213},"labels":[],"label_agreement":null},{"id":"W3012092751","doi":"10.1172/jci127750","title":"Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kidney Stones and Urolithiasis Treatments","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Common Fund; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; University of Tokyo; Royan Institute; Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; National Institutes of Health; University of Alberta","keywords":"Hypercalciuria; Reabsorption; Endocrinology; Claudin; Nephrocalcinosis; Internal medicine; Paracellular transport; Kidney stones; Kidney; Kidney disease; Calcium; Medicine; Biology; Tight junction; Cell biology; Permeability (electromagnetism)","score_opus":0.08169439349268456,"score_gpt":0.37744728199958955,"score_spread":0.29575288850690495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012092751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898746,0.002631622,0.0040177736,0.00056095986,0.00006246371,0.00005149343,0.000725133,0.00041541425,0.0016605884],"genre_scores_gemma":[0.9921678,0.0014006684,0.0028672917,0.00019304622,0.000044809807,0.000058665588,0.0008002978,0.00013423142,0.0023331977],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99937433,0.00017582049,0.0000714106,0.00015687525,0.0001467751,0.000074911506],"domain_scores_gemma":[0.9991818,0.00018392227,0.00034728087,0.000054191783,0.00003311919,0.00019958844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046130057,0.0011096273,0.00058690016,0.002499815,0.0005858581,0.00068498886,0.00046715522,0.0014292412,0.004973609],"category_scores_gemma":[0.0006069017,0.00060020824,0.0005115648,0.0008373249,0.000850554,0.0003592688,0.0007813657,0.001147981,0.0005458765],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018324952,0.00043917767,0.007972839,0.00016247576,0.00014578518,0.0056994287,0.00019328858,0.00029884095,0.9774665,0.001114508,0.00058615825,0.004088522],"study_design_scores_gemma":[0.0016262516,0.003367651,0.26584482,0.00036892033,0.0011565029,0.12639208,0.0007054609,0.010172442,0.5584737,0.004358827,0.027351813,0.00018157101],"about_ca_topic_score_codex":0.00084411976,"about_ca_topic_score_gemma":0.0008690924,"teacher_disagreement_score":0.004973609,"about_ca_system_score_codex":0.0003531794,"about_ca_system_score_gemma":0.00038008468,"threshold_uncertainty_score":0.016638398},"labels":[],"label_agreement":null},{"id":"W3012442502","doi":"10.1172/jci126567","title":"TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; Krembil Foundation; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Austrian Science Fund; Brigham and Women's Hospital","keywords":"Tyrosine kinase 2; Medicine; Immunology; Immunity; Immune system; Janus kinase; Disease; Ankylosing spondylitis; Biology; Receptor; Cytokine; Internal medicine","score_opus":0.08768227452592112,"score_gpt":0.34968374972924166,"score_spread":0.2620014752033205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012442502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937994,0.0024394381,0.0011821071,0.00015752352,0.000087797205,0.000038860955,0.0006823846,0.00017230595,0.0014402503],"genre_scores_gemma":[0.99289894,0.0018426528,0.0012962457,0.00010700153,0.00002256362,0.0000783102,0.00079708913,0.000032641747,0.0029245394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997974,0.00003584458,0.000024138073,0.00003254216,0.00004088453,0.00006914464],"domain_scores_gemma":[0.9998233,0.000019656054,0.000052645988,0.00001801908,0.000013377713,0.00007306119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017731349,0.000581839,0.00044598448,0.00037614972,0.00017596457,0.00032074196,0.00034216457,0.00041610142,0.0014672575],"category_scores_gemma":[0.000109983805,0.00018158562,0.00033089292,0.00021398914,0.00026159105,0.00023663977,0.0001443822,0.0013056439,0.00034965904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011789907,0.0003853475,0.00023332331,0.00008437301,0.000021608545,0.000056958626,0.000021031485,0.00022460792,0.99500895,0.00008666843,0.0001396102,0.0025585773],"study_design_scores_gemma":[0.0002394559,0.0048970818,0.0056912038,0.000020575182,0.000051733106,0.00019658147,0.00005574011,0.0018770454,0.9841086,0.00009919697,0.0027456963,0.00001700947],"about_ca_topic_score_codex":0.0005722932,"about_ca_topic_score_gemma":0.0014982783,"teacher_disagreement_score":0.0014672575,"about_ca_system_score_codex":0.0002660547,"about_ca_system_score_gemma":0.00027546711,"threshold_uncertainty_score":0.0049084425},"labels":[],"label_agreement":null},{"id":"W3012764207","doi":"10.1172/jci132139","title":"Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Birth, Development, and Health","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; Harvard Stem Cell Institute; Pew Charitable Trusts; American Liver Foundation; National Institutes of Health; Canadian Institutes of Health Research; Harvard Medical School; U.S. Department of Veterans Affairs","keywords":"Physiology; Medicine; Fetus; Population; Internal medicine; Obesity; Disease; Cohort; Zebrafish; Endocrinology; Adipose tissue; Biology; Bioinformatics; Pregnancy; Genetics; Environmental health","score_opus":0.09837560955142646,"score_gpt":0.38975481006903206,"score_spread":0.2913792005176056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012764207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99462056,0.00071776693,0.0014208927,0.00020754612,0.000017299477,0.000027015076,0.0006083391,0.000056033205,0.0023247022],"genre_scores_gemma":[0.99525166,0.0012900981,0.001528583,0.00013312526,0.000014296639,0.000028137889,0.0003755173,0.0000134363945,0.0013651678],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998952,0.000012423978,0.000008030333,0.000031383915,0.000027065493,0.00002592374],"domain_scores_gemma":[0.99984944,0.000010988272,0.00006900825,0.000011646486,0.000018447277,0.00004044775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011412163,0.0002681651,0.000193572,0.00054805644,0.00025726043,0.00018765869,0.000090255,0.00021782234,0.0019485821],"category_scores_gemma":[0.00028081806,0.00012256455,0.00016839308,0.00020257532,0.00023251938,0.00013193248,0.0004086679,0.00035844246,0.00018599188],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084201875,0.0001843347,0.5015669,0.0000929922,0.00007130238,0.0096251955,0.0006305475,0.000177132,0.4501802,0.0010506555,0.0010636114,0.03451515],"study_design_scores_gemma":[0.000009005302,0.0004273769,0.95743513,0.00006104498,0.000056824683,0.014353988,0.00039912493,0.0002793533,0.02242925,0.0004679885,0.004062222,0.000018674355],"about_ca_topic_score_codex":0.002805551,"about_ca_topic_score_gemma":0.0040449356,"teacher_disagreement_score":0.002805551,"about_ca_system_score_codex":0.000241193,"about_ca_system_score_gemma":0.00025079935,"threshold_uncertainty_score":0.0065187216},"labels":[],"label_agreement":null},{"id":"W3016056304","doi":"10.1172/jci136162","title":"(H)Elping nerve growth factor: Elp1 inhibits TrkA’s phosphatase to maintain retrograde signaling","year":2020,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Hereditary Neurological Disorders","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Nerve growth factor; Tropomyosin receptor kinase A; Cell biology; Neuroscience; Neurotrophin; Biology; Low-affinity nerve growth factor receptor; Signal transduction; Receptor; Genetics","score_opus":0.17430240895444746,"score_gpt":0.36131712887805945,"score_spread":0.187014719923612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016056304","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.036122102,0.00801845,0.0026590568,0.8399931,0.07195149,0.00020408686,0.00026019572,0.0007140621,0.04007738],"genre_scores_gemma":[0.17807955,0.009265607,0.002997744,0.6063458,0.15409799,0.00022489791,0.00021142582,0.00014796304,0.048629053],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973494,0.000052155872,0.000035490197,0.00004148924,0.00007290635,0.000062929634],"domain_scores_gemma":[0.99941957,0.0002732658,0.00005341508,0.000039214043,0.00010021404,0.000114450864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045249998,0.0007255154,0.00053605053,0.00033757434,0.0009806597,0.0008231853,0.00065913354,0.008908315,0.0034533562],"category_scores_gemma":[0.002524249,0.00027862404,0.00063031435,0.00019689175,0.0011578954,0.0009822788,0.0002972327,0.0065666065,0.0041972324],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001196914,0.0003513882,0.0051037776,0.00032031888,0.00010195379,0.077003695,0.00025563463,0.0005260022,0.0146256145,0.0073065576,0.83827335,0.054934815],"study_design_scores_gemma":[0.0013301246,0.0011294221,0.011247468,0.00024450495,0.00019434548,0.1227387,0.0005367285,0.0057400777,0.02602583,0.015513198,0.81513596,0.00016365983],"about_ca_topic_score_codex":0.0016318797,"about_ca_topic_score_gemma":0.002194853,"teacher_disagreement_score":0.008908315,"about_ca_system_score_codex":0.0012935719,"about_ca_system_score_gemma":0.00041593603,"threshold_uncertainty_score":0.011552572},"labels":[],"label_agreement":null},{"id":"W3016087872","doi":"10.1172/jci131241","title":"The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Wilson Centre","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Arthritis and Musculoskeletal and Skin Diseases; LEO Fondet; LEO Pharma Research Foundation; Danmarks Tekniske Universitet; University of Toronto; National Institutes of Health; H. Lundbeck A/S; Lundbeckfonden; Austrian Science Fund","keywords":"Biology; Autoimmunity; Immunology; Innate immune system; Immune system; Experimental autoimmune encephalomyelitis; RAR-related orphan receptor gamma; Inflammation; Cell biology; Cancer research; FOXP3","score_opus":0.0784254629536327,"score_gpt":0.3101577636133956,"score_spread":0.23173230065976289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016087872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903661,0.004304818,0.0022023257,0.00014086613,0.0000332533,0.000011056146,0.0002987579,0.000112169655,0.00253048],"genre_scores_gemma":[0.99670404,0.0010541582,0.00075600453,0.000051443792,0.000010465861,0.000011166147,0.00021731369,0.000012061871,0.0011832849],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991226,0.000019470926,0.000007702865,0.0000148705885,0.00002203836,0.000023611688],"domain_scores_gemma":[0.99990654,0.000010266721,0.000032613385,0.0000068131103,0.000008213275,0.000035466444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012342776,0.0002524918,0.0001261199,0.00014453083,0.00008196277,0.00024037274,0.00013075134,0.0001249597,0.0011777764],"category_scores_gemma":[0.00010853604,0.00008470726,0.00012970662,0.00006882691,0.00022347622,0.00013165714,0.00020591688,0.00036568413,0.0003391406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036150063,0.00001665797,0.0019254932,0.000050836927,0.000003680164,0.00016390027,0.000027385233,0.00007915139,0.9931732,0.0001690495,0.00007460325,0.003954501],"study_design_scores_gemma":[0.00003423064,0.000908782,0.051036417,0.00006054893,0.00004360731,0.0013514508,0.00017733009,0.001004471,0.938705,0.00019800778,0.00647283,0.0000072266366],"about_ca_topic_score_codex":0.00033843776,"about_ca_topic_score_gemma":0.0006332995,"teacher_disagreement_score":0.0011777764,"about_ca_system_score_codex":0.00021746977,"about_ca_system_score_gemma":0.00031397995,"threshold_uncertainty_score":0.0039401054},"labels":[],"label_agreement":null},{"id":"W3019093282","doi":"10.1172/jci139562","title":"Panic prescribing has become omnipresent during the COVID-19 pandemic","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Ontario; Lunenfeld-Tanenbaum Research Institute","funders":"School of Medicine, New York University","keywords":"Pandemic; Coronavirus disease 2019 (COVID-19); Panic; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Betacoronavirus; Coronavirus Infections; Medicine; Virology; Outbreak; Psychiatry; Pathology; Anxiety; Infectious disease (medical specialty); Disease","score_opus":0.42990160617605894,"score_gpt":0.4714331013280518,"score_spread":0.04153149515199284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019093282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83285624,0.009431863,0.0005428087,0.081476204,0.0019209731,0.00007590693,0.002609041,0.00013175704,0.070955195],"genre_scores_gemma":[0.9787942,0.0049286727,0.00030702885,0.01034907,0.0015513186,0.000023560382,0.0008076677,0.00003700472,0.0032015424],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99829096,0.0004152999,0.0001690104,0.00018789276,0.0005544534,0.00038243603],"domain_scores_gemma":[0.9926593,0.00155221,0.0028632975,0.00028878648,0.0008688736,0.0017674784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013906943,0.00014406398,0.0002950657,0.0006074952,0.0013860968,0.0028770799,0.00043128745,0.0016760606,0.0069573387],"category_scores_gemma":[0.012003967,0.00023077655,0.0003640802,0.001016168,0.0008431732,0.0013459784,0.0015464525,0.002820371,0.00091800507],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016230283,0.0003701026,0.75663453,0.00046756276,0.00018024447,0.0018366484,0.004337937,0.0003182085,0.0011821461,0.0035543188,0.037256733,0.19223846],"study_design_scores_gemma":[0.000054881963,0.00026984984,0.9518898,0.00038958734,0.000059095044,0.0014345306,0.0056283716,0.0003383912,0.00027737455,0.0009580229,0.038664255,0.000035882833],"about_ca_topic_score_codex":0.02014655,"about_ca_topic_score_gemma":0.043448433,"teacher_disagreement_score":0.02014655,"about_ca_system_score_codex":0.0021533056,"about_ca_system_score_gemma":0.0029102778,"threshold_uncertainty_score":0.040058553},"labels":[],"label_agreement":null},{"id":"W3020230577","doi":"10.1172/jci134260","title":"The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vector Institute; University of Toronto; Ontario Institute for Cancer Research; Institute of Cancer Research","funders":"National Cancer Institute; Canadian Institutes of Health Research; Genentech; Astellas Pharma; Academy of Medical Sciences; National Institute for Health and Care Research; Royal Marsden NHS Foundation Trust; Medical Research Council; Cancer Prevention and Research Institute of Texas; Daiichi Sankyo Europe; U.S. Department of Defense; Sanofi; Menarini Silicon Biosystems; National Institutes of Health; Vertex Pharmaceuticals","keywords":"Chromatin; Cancer; Prostate cancer; RNA polymerase; Polymerase; Biology; Prostate; Computational biology; Cancer research; RNA; Genetics; DNA; Gene","score_opus":0.03394731355091934,"score_gpt":0.3389273109901893,"score_spread":0.30497999743926996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020230577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844549,0.0068241926,0.0062308847,0.00010332771,0.000009884628,0.000009332241,0.00037471473,0.00009541134,0.0018973862],"genre_scores_gemma":[0.99749136,0.0008075715,0.00092730625,0.000025153462,0.000006657965,0.0000046304617,0.00021872607,0.000007173099,0.0005114917],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99994075,0.000009133752,0.000001854419,0.000025243666,0.000013341037,0.00000965683],"domain_scores_gemma":[0.9999579,0.0000080450645,0.000014774773,0.000003900354,0.0000057699376,0.000009681442],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000091668306,0.000117279014,0.00009998092,0.00025548218,0.00012557641,0.00029946357,0.000117935735,0.00012243782,0.0005827508],"category_scores_gemma":[0.00009999294,0.00011948983,0.00007430164,0.00023028487,0.00018991632,0.0001379274,0.00011654567,0.00014456887,0.00016048536],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007715676,0.00001050531,0.007940975,0.000046102603,0.00001501728,0.000059406048,0.0000462762,0.0005541101,0.98419696,0.000528761,0.00007915487,0.0064455215],"study_design_scores_gemma":[0.000019909461,0.000362488,0.46092275,0.000027902135,0.000090257505,0.0017762625,0.00021778555,0.012859251,0.5084448,0.0035316106,0.011714149,0.00003290837],"about_ca_topic_score_codex":0.00051171763,"about_ca_topic_score_gemma":0.001045861,"teacher_disagreement_score":0.0005827508,"about_ca_system_score_codex":0.00021201813,"about_ca_system_score_gemma":0.00011996271,"threshold_uncertainty_score":0.0019494891},"labels":[],"label_agreement":null},{"id":"W3022842541","doi":"10.1172/jci45627","title":"Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Bundesministerium für Bildung und Forschung; Radboud Universiteit; Eberhard Karls Universität Tübingen; Foundation Fighting Blindness","keywords":"Intraflagellar transport; Cilium; Cell biology; Biology; Retinal degeneration; Motile cilium; Bardet–Biedl syndrome; Opsin; Ciliogenesis; Mutation; Retina; Genetics; Flagellum; Retinal; Neuroscience; Phenotype; Biochemistry; Rhodopsin; Gene","score_opus":0.04728480994124895,"score_gpt":0.30876385108544757,"score_spread":0.2614790411441986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022842541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950033,0.0011923021,0.0023147645,0.00015165287,0.000018574245,0.000021275055,0.00031137423,0.00014997,0.00083677383],"genre_scores_gemma":[0.9967428,0.0004261995,0.0017960327,0.00006555807,0.0000064517103,0.000019101883,0.00022557145,0.000023098866,0.0006952448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977654,0.000032875934,0.00002966784,0.000075495154,0.00005078467,0.000034698023],"domain_scores_gemma":[0.9998921,0.00001652214,0.000042284624,0.000010883902,0.0000055360133,0.000032664273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020702997,0.00045763818,0.00022186949,0.000805715,0.00030218097,0.00031666298,0.00014650768,0.00062432897,0.0017587134],"category_scores_gemma":[0.00027154683,0.00025818776,0.00025890904,0.00018961162,0.0005071892,0.00019448147,0.00036993827,0.00039922947,0.00032395462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025092397,0.00003518427,0.0042286627,0.00006229764,0.000032248867,0.0015501571,0.000057497113,0.00012041324,0.9894276,0.00047583572,0.00013656246,0.003622682],"study_design_scores_gemma":[0.00018323855,0.0008778041,0.1737977,0.00006357176,0.0002564506,0.032157574,0.00020572222,0.0040054196,0.7785026,0.0010838034,0.008825422,0.00004077324],"about_ca_topic_score_codex":0.00096793036,"about_ca_topic_score_gemma":0.00133013,"teacher_disagreement_score":0.0017587134,"about_ca_system_score_codex":0.00042815827,"about_ca_system_score_gemma":0.0002540292,"threshold_uncertainty_score":0.005883515},"labels":[],"label_agreement":null},{"id":"W3025806951","doi":"10.1172/jci132765","title":"Nonalcoholic fatty liver disease in CLOCK mutant mice","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; NIH Office of the Director; National Heart, Lung, and Blood Institute; National Institutes of Health; School of Medicine, New York University; York University; American Heart Association; U.S. Department of Veterans Affairs","keywords":"Nonalcoholic fatty liver disease; Steatosis; Biology; Endocrinology; Internal medicine; Fatty liver; CD36; Lipid metabolism; Apolipoprotein E; Medicine; Disease; Receptor","score_opus":0.1356310184337244,"score_gpt":0.38460247156713373,"score_spread":0.24897145313340932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025806951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9657616,0.0018893757,0.01961913,0.0009344689,0.00035246668,0.00043122642,0.006686241,0.0009972265,0.0033281867],"genre_scores_gemma":[0.91628647,0.0048064054,0.0369766,0.00076988625,0.00015471056,0.0019199948,0.0069540828,0.00065217225,0.03147967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994289,0.00008163263,0.000099099125,0.00017295148,0.000120344936,0.00009705835],"domain_scores_gemma":[0.9992242,0.000057541933,0.00031742192,0.000079750294,0.000055625158,0.00026539635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005661592,0.0011002,0.00047755698,0.0017249107,0.0006190243,0.0007062901,0.0006852464,0.0012016046,0.0056215767],"category_scores_gemma":[0.00028343848,0.0007990862,0.0006601495,0.00062912056,0.0007250375,0.00057526765,0.0005124325,0.0015769409,0.0014469237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018152965,0.00065706595,0.001035134,0.00014096897,0.000028957482,0.0004542543,0.0001048909,0.0001918416,0.99002635,0.0008816508,0.00042973922,0.004233944],"study_design_scores_gemma":[0.002147224,0.004413105,0.029641189,0.00019059321,0.000208025,0.0061562695,0.00043853524,0.00577761,0.9259481,0.0012155911,0.023769042,0.00009465745],"about_ca_topic_score_codex":0.00097282144,"about_ca_topic_score_gemma":0.0017614253,"teacher_disagreement_score":0.0056215767,"about_ca_system_score_codex":0.00051205966,"about_ca_system_score_gemma":0.00048755005,"threshold_uncertainty_score":0.01880604},"labels":[],"label_agreement":null},{"id":"W3026962176","doi":"10.1172/jci127668","title":"Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; National Health and Medical Research Council; Australian Research Council; Genentech; National Institutes of Health; Royal Society; Korea Advanced Institute of Science and Technology; British Heart Foundation; University of Toronto; Medical Research Council; Peter MacCallum Cancer Centre; Francis Crick Institute; Australian Government; University of Texas Southwestern Medical Center","keywords":"Retina; Retinal; Hypoxia (environmental); Neovascularization; Ischemia; Retinopathy; Diabetic retinopathy; Apoptosis; Biology; Ophthalmology; Angiogenesis; Medicine; Cancer research; Internal medicine; Chemistry; Endocrinology; Neuroscience; Diabetes mellitus; Biochemistry; Oxygen","score_opus":0.11720518130026093,"score_gpt":0.36678070110631056,"score_spread":0.24957551980604964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026962176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868663,0.0042016874,0.0049169594,0.0004392606,0.00018570741,0.00012734425,0.00018664719,0.00027064135,0.0028054265],"genre_scores_gemma":[0.9856967,0.003181215,0.005594562,0.00022322485,0.000054728072,0.00014972522,0.00033363717,0.000036497386,0.0047296532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99965763,0.00007047474,0.00003859253,0.000062422456,0.00008156718,0.000089398985],"domain_scores_gemma":[0.9998318,0.000029675506,0.000046361838,0.000030187995,0.000019130735,0.000042798638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004702821,0.0005794471,0.0006088286,0.00051106204,0.00021205776,0.00037466435,0.0003881449,0.00048888824,0.0011906406],"category_scores_gemma":[0.00022165613,0.00029132172,0.00032350124,0.00025933448,0.00033424448,0.00034969204,0.00018624903,0.001418795,0.0002191326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007288349,0.00049288286,0.00010353222,0.000103300255,0.000018546325,0.0001052737,0.00004225835,0.00014931477,0.9933334,0.00027385147,0.00015285217,0.0044958754],"study_design_scores_gemma":[0.0002311635,0.006946015,0.0027191895,0.000021867687,0.00005703779,0.0004765161,0.000047484464,0.0027413087,0.98381203,0.00017629097,0.0027599593,0.000011141634],"about_ca_topic_score_codex":0.00089628884,"about_ca_topic_score_gemma":0.0013140448,"teacher_disagreement_score":0.0011906406,"about_ca_system_score_codex":0.00033562808,"about_ca_system_score_gemma":0.0003690286,"threshold_uncertainty_score":0.0039830804},"labels":[],"label_agreement":null},{"id":"W3033380374","doi":"10.1172/jci134965","title":"PRICKLE3 linked to ATPase biogenesis manifested Leber’s hereditary optic neuropathy","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents; Institute of Genetics; National Natural Science Foundation of China; Zhejiang University; Cincinnati Children's Hospital Medical Center","keywords":"Mutation; Mitochondrial DNA; Optic neuropathy; Biology; Mitochondrion; Leber's hereditary optic neuropathy; Genetics; Molecular biology; Mitochondrial biogenesis; Mitochondrial disease; Phenotype; Gene; Optic nerve","score_opus":0.080816431606739,"score_gpt":0.33509887695391605,"score_spread":0.25428244534717703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033380374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99814117,0.00019640762,0.0008638499,0.000060745268,0.000022976756,0.000010925272,0.00012789205,0.00004603938,0.0005299977],"genre_scores_gemma":[0.99860185,0.00012065958,0.0004883778,0.000041360643,0.000007428649,0.0000067999126,0.00010098796,0.0000090299845,0.00062355073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991643,0.0000086360715,0.000010779134,0.000032465497,0.000015015151,0.000016764916],"domain_scores_gemma":[0.9999088,0.000014762809,0.00003611372,0.00000731397,0.0000066076905,0.000026495294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008676615,0.0005272585,0.0002267392,0.00026485202,0.00031596274,0.00014606133,0.00015010654,0.00041940215,0.0012454552],"category_scores_gemma":[0.00015392802,0.0001258472,0.00026622927,0.00015881858,0.0003061815,0.00013645935,0.00031537918,0.00036498057,0.00020327515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003639035,0.000049914957,0.013833489,0.000089757086,0.000047933074,0.028656945,0.00018019212,0.00023122257,0.9522574,0.00044233486,0.00022489135,0.0036220262],"study_design_scores_gemma":[0.00017449843,0.0007503342,0.2778254,0.000054349413,0.00031587313,0.12886107,0.000334184,0.0053853663,0.5783243,0.0010221254,0.006864663,0.000087835426],"about_ca_topic_score_codex":0.001193014,"about_ca_topic_score_gemma":0.0013407297,"teacher_disagreement_score":0.0012454552,"about_ca_system_score_codex":0.00024589172,"about_ca_system_score_gemma":0.00020449344,"threshold_uncertainty_score":0.004166484},"labels":[],"label_agreement":null},{"id":"W3033796830","doi":"10.1172/jci140530","title":"Is innate immunity our best weapon for flattening the curve?","year":2020,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Institute of Infection and Immunity; Ottawa Hospital","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; University of Ottawa","keywords":"Innate immune system; Pandemic; Immunology; Immunity; Virology; Virus; Battle; Death toll; Biology; Disease; Coronavirus disease 2019 (COVID-19); Immune system; Medicine; Environmental health; Geography; Infectious disease (medical specialty)","score_opus":0.23786809131857245,"score_gpt":0.46412660741812733,"score_spread":0.22625851609955488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033796830","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000050800263,0.99553776,0.00008850695,0.0022344284,0.0013552655,0.000002385887,0.000011519744,0.000012060851,0.00070735975],"genre_scores_gemma":[0.00054685265,0.9957984,0.00013109158,0.0014752335,0.0010260126,0.0000048209413,0.00002223289,0.0000031232726,0.0009921368],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99968207,0.00008190381,0.000034179626,0.000046424397,0.00011352732,0.00004189458],"domain_scores_gemma":[0.9992054,0.00037441676,0.000064548854,0.000030574032,0.00022983001,0.00009532201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001015052,0.0007723104,0.0013377272,0.0013665206,0.00034226375,0.0014449017,0.0011538782,0.001926862,0.0048698382],"category_scores_gemma":[0.0017803345,0.00023752225,0.0005269995,0.0011152836,0.0009722002,0.0024370109,0.00073836977,0.0043398757,0.0039396863],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001162196,0.00006538145,0.00016760812,0.008564754,0.00007232506,0.0001273093,0.00007180666,0.00022427482,0.0010091487,0.0070694345,0.16417962,0.81833214],"study_design_scores_gemma":[0.000011978531,0.00006591731,0.00028195741,0.0023109592,0.000032010787,0.000409631,0.000052050334,0.000038049726,0.00013041178,0.002835133,0.9938214,0.000010552101],"about_ca_topic_score_codex":0.000817544,"about_ca_topic_score_gemma":0.0014876626,"teacher_disagreement_score":0.0048698382,"about_ca_system_score_codex":0.0009191096,"about_ca_system_score_gemma":0.0013077823,"threshold_uncertainty_score":0.01629126},"labels":[],"label_agreement":null},{"id":"W3034286795","doi":"10.1172/jci140200","title":"Early safety indicators of COVID-19 convalescent plasma in 5000 patients","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":485,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; Mayo Clinic; Natural Sciences and Engineering Research Council of Canada; Biomedical Advanced Research and Development Authority; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Takeda Oncology; U.S. Department of Health and Human Services","keywords":"Convalescent plasma; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Medicine; Coronavirus Infections; Internal medicine; Outbreak; Disease","score_opus":0.14357194647938826,"score_gpt":0.4666201806068777,"score_spread":0.32304823412748945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034286795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99758184,0.000594486,0.0005317105,0.00007624515,0.000011274415,0.000049425053,0.00060632714,0.000012820758,0.00053573004],"genre_scores_gemma":[0.998197,0.00015947793,0.00036580296,0.000064192944,0.000025519144,0.000047418347,0.0010058584,0.000002194244,0.00013258585],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99904126,0.00024373655,0.00020590196,0.00012970254,0.00025527665,0.00012419294],"domain_scores_gemma":[0.9961706,0.000763897,0.0020939372,0.00017211065,0.0004547558,0.00034468266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016215075,0.0002860269,0.00035393727,0.00044186518,0.00027325936,0.0005694436,0.00018764223,0.00024091215,0.0011608861],"category_scores_gemma":[0.0042171595,0.0000992636,0.0005436137,0.00034119273,0.00014788132,0.0003419505,0.00038013575,0.00059464487,0.00012479632],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020273682,0.00011673399,0.9864238,0.00005257665,0.00010754182,0.00015916146,0.00008286581,0.00037056117,0.0006054258,0.00008790452,0.00045079875,0.009515179],"study_design_scores_gemma":[0.000063765096,0.0029821966,0.99242276,0.00003212793,0.00010721399,0.00050045236,0.00011890981,0.0015446628,0.0011988666,0.000088628825,0.00092807616,0.000012308163],"about_ca_topic_score_codex":0.00043371852,"about_ca_topic_score_gemma":0.00055589573,"teacher_disagreement_score":0.0016215075,"about_ca_system_score_codex":0.0004576895,"about_ca_system_score_gemma":0.0003954287,"threshold_uncertainty_score":0.008575499},"labels":[],"label_agreement":null},{"id":"W3034536401","doi":"10.1172/jci138179","title":"Impact of TREM2R47H variant on tau pathology–induced gliosis and neurodegeneration","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":278,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec; University of Victoria","funders":"National Center for Advancing Translational Sciences; NIH Office of the Director; Genentech; National Cancer Institute; Idorsia Pharmaceuticals; National Center for Research Resources; Georgia Clinical and Translational Science Alliance; National Institute on Aging; Center for Cellular Imaging, Washington University; Hope Center for Neurological Disorders; National Institutes of Health; Alvin J. Siteman Cancer Center; Edward N. and Della L. Thome Memorial Foundation; Charles and Helen Schwab Foundation; Amgen; Children's Discovery Institute; Office of Research Infrastructure Programs, National Institutes of Health; Foundation for Barnes-Jewish Hospital; JPB Foundation","keywords":"Gliosis; Neurodegeneration; Tau pathology; Pathology; Neuroscience; Medicine; Biology; Alzheimer's disease; Disease","score_opus":0.20957113659716828,"score_gpt":0.39105200857708144,"score_spread":0.18148087197991317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034536401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99877053,0.00033757687,0.00017593778,0.00003221954,0.000019588113,0.000020041427,0.00016651754,0.000020662867,0.00045682755],"genre_scores_gemma":[0.99815995,0.0002687178,0.0003512167,0.000050254133,0.000014118166,0.000023069539,0.00024294881,0.000013867375,0.0008758431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998006,0.000040630377,0.000021714011,0.000042159918,0.000044815526,0.000050070154],"domain_scores_gemma":[0.99987614,0.000017379347,0.000036638823,0.00001360003,0.000011619693,0.000044661258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018943415,0.00040093716,0.0004094127,0.00016659526,0.00014037207,0.00021882528,0.00020289716,0.00040254358,0.0017287575],"category_scores_gemma":[0.00017235664,0.00011674198,0.0003238382,0.00011445215,0.0002730237,0.00018561611,0.0001499752,0.00042996198,0.0002980565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018979446,0.00043702207,0.0007737519,0.00006535531,0.000039831364,0.00048152474,0.000023520484,0.00014247494,0.993804,0.00011186772,0.00010057217,0.002122183],"study_design_scores_gemma":[0.00039064427,0.015470636,0.040054243,0.000025589894,0.00024847809,0.0026775394,0.00011294862,0.0027816845,0.9349548,0.00016321128,0.0030895495,0.00003074163],"about_ca_topic_score_codex":0.00056751876,"about_ca_topic_score_gemma":0.0007118899,"teacher_disagreement_score":0.0017287575,"about_ca_system_score_codex":0.00018470758,"about_ca_system_score_gemma":0.00017516805,"threshold_uncertainty_score":0.0057832003},"labels":[],"label_agreement":null},{"id":"W3034909353","doi":"10.1172/jci137040","title":"Tau is not necessary for amyloid-β–induced synaptic and memory impairments","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Aging; National Institute of Neurological Disorders and Stroke; Fakulta Životního Prostředí, Česká Zemědělská Univerzita v Praze; Canadian Institutes of Health Research","keywords":"Neuroscience; Amyloid (mycology); Psychology; Cognitive science; Cognitive psychology; Medicine; Pathology","score_opus":0.18047145268090073,"score_gpt":0.4317216981309561,"score_spread":0.25125024545005537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034909353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99066,0.003555654,0.0011447095,0.00025372428,0.0001314726,0.000030740266,0.0003256328,0.000090499074,0.0038076108],"genre_scores_gemma":[0.9956256,0.0010873281,0.00069485116,0.00008645772,0.000029143343,0.000029867706,0.00046471794,0.000021065,0.0019608317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998022,0.000025921205,0.000029127628,0.000037429945,0.00006482072,0.000040532177],"domain_scores_gemma":[0.9995571,0.000063238884,0.000091338225,0.00008648868,0.000075907876,0.00012583897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021992884,0.0002903706,0.0005246651,0.0004268739,0.00025805586,0.00042268776,0.0003773261,0.00055310986,0.0025190627],"category_scores_gemma":[0.00041314692,0.0001877396,0.0003401771,0.00018187534,0.0004725289,0.00040462957,0.00023958314,0.0007930944,0.0006824404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067408313,0.0002059733,0.00056968327,0.000093334,0.000033796434,0.00040656896,0.000028682443,0.00004128287,0.9951703,0.00028835746,0.00013919463,0.0023487695],"study_design_scores_gemma":[0.00013912238,0.0021949229,0.021162929,0.00005500274,0.00015537773,0.0035082244,0.000111624766,0.0009545182,0.9643052,0.000883372,0.0065130023,0.000016642281],"about_ca_topic_score_codex":0.000438719,"about_ca_topic_score_gemma":0.00070483604,"teacher_disagreement_score":0.0025190627,"about_ca_system_score_codex":0.00019459166,"about_ca_system_score_gemma":0.0003766418,"threshold_uncertainty_score":0.008427143},"labels":[],"label_agreement":null},{"id":"W3036458210","doi":"10.1172/jci132513","title":"Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"Cancer Council NSW; Victorian Cancer Agency","keywords":"Smoothened; Cilium; Biology; Cell biology; Hedgehog signaling pathway; Hedgehog; Transmembrane protein; Signal transduction; Cancer research; Ligand (biochemistry); Genetics; Receptor","score_opus":0.08155267301840147,"score_gpt":0.34320489610353916,"score_spread":0.2616522230851377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036458210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992322,0.00390629,0.0015038966,0.00016834274,0.000016520537,0.000012039378,0.00010641227,0.00007144066,0.0018929982],"genre_scores_gemma":[0.9978865,0.00063405774,0.00046875395,0.000021391306,0.0000056753747,0.000010338834,0.00006549655,0.0000047741105,0.00090300036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985266,0.000031777472,0.000008589524,0.000018460447,0.000038867052,0.000049588984],"domain_scores_gemma":[0.99991703,0.000008588651,0.000031908858,0.0000071048185,0.000009096305,0.00002620974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016401318,0.00024413178,0.00015349506,0.0002652265,0.00017935841,0.00034555036,0.0001483669,0.00025735167,0.0006514405],"category_scores_gemma":[0.00015040167,0.00012422998,0.00017140034,0.00008944303,0.0002906958,0.00018641105,0.00019476576,0.00026915563,0.00024285605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000318897,0.00002225087,0.0009649187,0.000025157718,0.000006815317,0.00017935954,0.000016391341,0.000108679946,0.9950376,0.00042260042,0.00007029678,0.0028270024],"study_design_scores_gemma":[0.00005528629,0.00032267298,0.03666674,0.000011091043,0.000040881845,0.0012747579,0.000078121644,0.0021128007,0.9555049,0.00034726443,0.0035772258,0.0000082775],"about_ca_topic_score_codex":0.00046986024,"about_ca_topic_score_gemma":0.00073605665,"teacher_disagreement_score":0.0006514405,"about_ca_system_score_codex":0.0003646476,"about_ca_system_score_gemma":0.00021227585,"threshold_uncertainty_score":0.002645731},"labels":[],"label_agreement":null},{"id":"W3037123232","doi":"10.1172/jci136174","title":"Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; National Institutes of Health; Iowa State University; Florida State University; National Institute on Aging; Brigham and Women's Hospital","keywords":"Neuroinflammation; Neurodegeneration; FYN; Downregulation and upregulation; Microglia; Neuroscience; Cell biology; Biology; Signal transduction; Medicine; Inflammation; Immunology; Disease; Internal medicine; Biochemistry; Proto-oncogene tyrosine-protein kinase Src","score_opus":0.13248442661624749,"score_gpt":0.3374277344465723,"score_spread":0.20494330783032483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037123232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98573744,0.012072468,0.00094915164,0.00021271486,0.000024257482,0.000014232155,0.00018664415,0.000039577677,0.0007634179],"genre_scores_gemma":[0.99553585,0.0033607583,0.0003877372,0.000084460524,0.000017137398,0.0000115225785,0.00015070292,0.000005913084,0.00044604114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999249,0.000013439266,0.0000089961895,0.000019752839,0.000013945176,0.000018987752],"domain_scores_gemma":[0.9999473,0.0000045656107,0.000026321051,0.0000028085396,0.000008647737,0.000010304827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013871481,0.00026295235,0.0002959204,0.0001519859,0.00015659201,0.0002786724,0.000108242304,0.0003066477,0.00042404965],"category_scores_gemma":[0.00010261983,0.00008746512,0.0002517435,0.00012376801,0.00024315053,0.00023160999,0.00013434031,0.00036839416,0.00011124796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016322416,0.000053618398,0.0077425665,0.0002894219,0.00005626469,0.00038784018,0.000119473785,0.0003021443,0.9787597,0.00018332884,0.00023687935,0.010236585],"study_design_scores_gemma":[0.00024367213,0.0022850584,0.47843367,0.00016933688,0.0005399603,0.0053676683,0.00041009454,0.003733252,0.49396917,0.002173264,0.012623458,0.00005143186],"about_ca_topic_score_codex":0.00054854143,"about_ca_topic_score_gemma":0.00072664506,"teacher_disagreement_score":0.00054854143,"about_ca_system_score_codex":0.00038876652,"about_ca_system_score_gemma":0.00014458693,"threshold_uncertainty_score":0.0028207302},"labels":[],"label_agreement":null},{"id":"W3040062773","doi":"10.1172/jci135373","title":"LIN28B promotes the development of neuroendocrine prostate cancer","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; China Scholarship Council; Terry Fox Research Institute; National Natural Science Foundation of China; U.S. Department of Defense","keywords":"SOX2; Prostate cancer; Cancer research; Biology; HMGA2; Carcinogenesis; Neuroendocrine differentiation; CD44; Cancer stem cell; Stem cell; Prostate; Transcription factor; Cancer; Cell; Cell biology; microRNA; Gene; Genetics","score_opus":0.20406593367824788,"score_gpt":0.45205943056501474,"score_spread":0.24799349688676686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3040062773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9798248,0.008901335,0.004264316,0.0004245891,0.00014472943,0.00006234426,0.0005682914,0.0004041952,0.005405321],"genre_scores_gemma":[0.9944622,0.00159749,0.0006979623,0.00010216134,0.000009388938,0.000028849336,0.0003506014,0.00003117097,0.0027202733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998783,0.000021977607,0.0000075507405,0.00002384209,0.00004235725,0.000026033327],"domain_scores_gemma":[0.99991345,0.000008022825,0.000016168346,0.000007592613,0.000010903915,0.000043906046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013758351,0.00020327941,0.00020541035,0.00020676109,0.00014263354,0.00026200665,0.0001153099,0.00021694042,0.0022590775],"category_scores_gemma":[0.0001131572,0.000108359716,0.00021854296,0.00009377281,0.00018776448,0.00012466668,0.00024036084,0.000804371,0.0004947678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035028043,0.00012338665,0.0015932356,0.00014679394,0.000023498906,0.00016426679,0.000040001927,0.00015294972,0.989042,0.00022657169,0.00057841605,0.0075586224],"study_design_scores_gemma":[0.00017181007,0.0024040688,0.044537015,0.000052228337,0.00013211495,0.0020563279,0.00023355965,0.0036026298,0.90324634,0.0004982005,0.04304451,0.000021153859],"about_ca_topic_score_codex":0.00045882742,"about_ca_topic_score_gemma":0.0008678648,"teacher_disagreement_score":0.0022590775,"about_ca_system_score_codex":0.00018854687,"about_ca_system_score_gemma":0.00031515647,"threshold_uncertainty_score":0.0075573325},"labels":[],"label_agreement":null},{"id":"W3041489599","doi":"10.1172/jci137536","title":"Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Medical Research Council; Medical Research Council; Duke-NUS Medical School; Wellcome Trust; Wellcome","keywords":"Dengue virus; Dengue fever; PCSK9; Viremia; Virology; Biology; Antibody-dependent enhancement; Cholesterol; Immunology; LDL receptor; Flavivirus; Virus; Lipoprotein; Endocrinology","score_opus":0.11395871799666214,"score_gpt":0.4184368176407498,"score_spread":0.3044780996440877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041489599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99768925,0.0005652978,0.0005073943,0.00010270615,0.00003913846,0.00001998288,0.0003214467,0.000019815085,0.0007349692],"genre_scores_gemma":[0.9977704,0.0004219677,0.0003593434,0.000049156086,0.0000072263897,0.000017019802,0.00038496405,0.0000044548697,0.0009854572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998747,0.000022631702,0.000014423803,0.000020645466,0.000022327393,0.000045271932],"domain_scores_gemma":[0.9999368,0.000010337043,0.000016811768,0.000008483911,0.00000674536,0.000020698677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011547793,0.00013191663,0.00018246521,0.00010543922,0.00010965665,0.00024462992,0.00006241375,0.0001331375,0.0015593383],"category_scores_gemma":[0.00013430753,0.00006711611,0.00019675457,0.00012645661,0.00014413736,0.00011811197,0.00015892812,0.00062802184,0.00016001519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021103497,0.00021724819,0.008859542,0.000074527874,0.00005219603,0.00012901834,0.000041000676,0.00019646907,0.97632754,0.00021279686,0.00025597162,0.01152335],"study_design_scores_gemma":[0.00018771554,0.003487903,0.21682213,0.000022280261,0.00013569562,0.0009824936,0.00018562752,0.0020437995,0.7696393,0.0004253727,0.006049053,0.00001859022],"about_ca_topic_score_codex":0.0005373163,"about_ca_topic_score_gemma":0.0008598296,"teacher_disagreement_score":0.0015593383,"about_ca_system_score_codex":0.00024997146,"about_ca_system_score_gemma":0.00018112341,"threshold_uncertainty_score":0.005216539},"labels":[],"label_agreement":null},{"id":"W3042402536","doi":"10.1172/jci133780","title":"A coagulation defect arising from heterozygous premature termination of tissue factor","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nutrasource","funders":"National Heart, Lung, and Blood Institute; NIHR BioResource; National Institute for Health and Care Research; Nihon Superior; NHS Blood and Transplant; Hemostasis and Thrombosis Research Society; Swedish Orphan Biovitrum; Department of Health and Social Care; CSL Behring; National Institutes of Health; National Hemophilia Foundation","keywords":"Tissue factor; Coagulation; Medicine; Factor IX; Heterozygote advantage; Internal medicine; Biology; Genetics; Allele","score_opus":0.14159140759539438,"score_gpt":0.39934002601503693,"score_spread":0.2577486184196426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042402536","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98835677,0.0010798625,0.00767045,0.00019981732,0.000094790696,0.00005404963,0.0008711264,0.00023768484,0.0014354744],"genre_scores_gemma":[0.9965856,0.00038952296,0.0017905115,0.0000671252,0.000034087247,0.000011372069,0.00026557673,0.000029252205,0.0008268809],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998361,0.000030319718,0.000022955184,0.000054644657,0.000035980465,0.000019910874],"domain_scores_gemma":[0.99968565,0.00012722508,0.000100333964,0.00001811888,0.000010937901,0.000057678466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016133075,0.00082151545,0.00030192785,0.0005074544,0.0002293302,0.00015713107,0.00018672949,0.00077071873,0.0017414131],"category_scores_gemma":[0.00050517457,0.00012411654,0.00034639012,0.00026867285,0.00060934765,0.000101818696,0.00024172482,0.0004638835,0.00035099027],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008556259,0.000091896865,0.012873175,0.0002007842,0.0001056163,0.1392047,0.0002366942,0.0003443856,0.82416147,0.0017082207,0.0008934791,0.019323956],"study_design_scores_gemma":[0.00016652151,0.0015137229,0.060480952,0.000084531646,0.0002133225,0.5433273,0.00013395293,0.0025129016,0.38083613,0.0010638346,0.00960963,0.000057160763],"about_ca_topic_score_codex":0.00047023076,"about_ca_topic_score_gemma":0.0004726435,"teacher_disagreement_score":0.0017414131,"about_ca_system_score_codex":0.00018575334,"about_ca_system_score_gemma":0.00024602,"threshold_uncertainty_score":0.005825579},"labels":[],"label_agreement":null},{"id":"W3045373257","doi":"10.1172/jci140461","title":"Diagnostic accuracy of 3 urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institutes of Health; Global Health Innovative Technology Fund; Department of Foreign Affairs and Trade, Australian Government; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation; McMaster University; Department for International Development; Ministerie van Buitenlandse Zaken; Bundesministerium für Bildung und Forschung","keywords":"Lipoarabinomannan; Medicine; Point-of-care testing; Tuberculosis; Tuberculosis diagnosis; Human immunodeficiency virus (HIV); Urine; Mycobacterium tuberculosis; Internal medicine; Immunology; Virology; Pathology","score_opus":0.13226162645596107,"score_gpt":0.41987120717778026,"score_spread":0.2876095807218192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045373257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988813,0.0005916727,0.00017146801,0.000027662452,0.000006714851,0.000011247769,0.000059963193,0.000010797116,0.00023927703],"genre_scores_gemma":[0.9993812,0.000081244834,0.000383927,0.000026003738,0.0000052938794,0.000007074824,0.000071783084,0.0000012706932,0.000042335505],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99705756,0.0013179539,0.00031761295,0.00047836485,0.0006100568,0.00021839775],"domain_scores_gemma":[0.9960853,0.0016079249,0.001276242,0.00021393922,0.00058302307,0.00023363008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029932286,0.00053068297,0.00041098997,0.0012655184,0.00032090407,0.0009380191,0.0005832451,0.00066636375,0.00064066367],"category_scores_gemma":[0.010970892,0.00042345078,0.0004291097,0.00040420186,0.0004395351,0.00031048025,0.00056094973,0.00033680876,0.00017268315],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043391043,0.00006666491,0.9922232,0.000030827345,0.00007159006,0.0001446817,0.00022451073,0.00010937585,0.001905726,0.000017175782,0.000054988246,0.004717374],"study_design_scores_gemma":[0.000061449995,0.0010827759,0.98739606,0.00005608564,0.00016147742,0.0021542064,0.0004482241,0.0035198848,0.0046755443,0.00003936762,0.00038592322,0.000018875033],"about_ca_topic_score_codex":0.0019951,"about_ca_topic_score_gemma":0.002624768,"teacher_disagreement_score":0.0029932286,"about_ca_system_score_codex":0.0005173585,"about_ca_system_score_gemma":0.00021425638,"threshold_uncertainty_score":0.015829861},"labels":[],"label_agreement":null},{"id":"W3046286246","doi":"10.1172/jci141718","title":"Is multisystem inflammatory syndrome in children on the Kawasaki syndrome spectrum?","year":2020,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Roy J. and Lucille A. Carver College of Medicine, University of Iowa; Hospital for Sick Children; University of Toronto","keywords":"Kawasaki disease; Medicine; Systemic inflammatory response syndrome; Disease; Cardiogenic shock; Acute coronary syndrome; Immunology; Multisystem disease; Toxic shock syndrome; Intensive care medicine; Pediatrics; Sepsis; Pathology; Cardiology; Staphylococcus aureus","score_opus":0.07953073666397678,"score_gpt":0.34177037380620096,"score_spread":0.2622396371422242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046286246","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11373969,0.038339216,0.0019099739,0.7946289,0.019840682,0.00015532473,0.00019408613,0.00022096842,0.030971175],"genre_scores_gemma":[0.55745643,0.040479515,0.0027468456,0.3100745,0.0808831,0.00012558399,0.00019150625,0.00007272709,0.007969841],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9989017,0.00033648364,0.00014841888,0.00016615819,0.00026004366,0.0001871912],"domain_scores_gemma":[0.9978703,0.00086417573,0.00032134843,0.00010280115,0.00038818395,0.00045319553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082550885,0.00077259267,0.0012223736,0.0010124785,0.001523737,0.001253969,0.0007310608,0.0071541774,0.0017386947],"category_scores_gemma":[0.006591948,0.00047269804,0.0005942457,0.0010330383,0.0015739391,0.0025868656,0.00068769616,0.007369989,0.0011021963],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002673783,0.00016970269,0.16662915,0.0004044074,0.00010051089,0.6024507,0.0013721851,0.00031811668,0.0015997734,0.0044792024,0.18020922,0.041999776],"study_design_scores_gemma":[0.000108345695,0.00018041789,0.040219136,0.0010003248,0.0001083829,0.87849885,0.0019195761,0.001096723,0.00044136652,0.005878207,0.07046978,0.0000788488],"about_ca_topic_score_codex":0.002940691,"about_ca_topic_score_gemma":0.0043308996,"teacher_disagreement_score":0.0071541774,"about_ca_system_score_codex":0.0017482436,"about_ca_system_score_gemma":0.0011169326,"threshold_uncertainty_score":0.012684464},"labels":[],"label_agreement":null},{"id":"W3049131713","doi":"10.1172/jci140585","title":"Coordination of metabolism, arousal, and reward by orexin/hypocretin neurons","year":2020,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Orexin; Arousal; Lateral hypothalamus; Orexin-A; Neuroscience; Homeostasis; Hypothalamus; Energy homeostasis; Biology; Psychology; Endocrinology; Internal medicine; Neuropeptide; Medicine; Obesity; Receptor","score_opus":0.1580094640168639,"score_gpt":0.39018378958739686,"score_spread":0.23217432557053297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3049131713","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04238587,0.004650144,0.001462464,0.86740285,0.04421358,0.00012279442,0.00021677407,0.0003189639,0.03922648],"genre_scores_gemma":[0.26237985,0.00793273,0.0023216286,0.523269,0.12625253,0.00023798087,0.00025337448,0.00012157864,0.07723133],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997613,0.0000552031,0.000033256743,0.000025644027,0.000086197775,0.000038408016],"domain_scores_gemma":[0.99933666,0.00028011238,0.00006947359,0.00006166805,0.00015994438,0.000092097616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049435603,0.00028954347,0.00036118383,0.00025555844,0.00068149803,0.00073583506,0.00051562826,0.005613336,0.003023652],"category_scores_gemma":[0.001960397,0.00020009854,0.00033901466,0.0001472181,0.00066727726,0.00055238046,0.0002444553,0.0047645876,0.0025880986],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012212329,0.00039229376,0.0064510563,0.00019570805,0.00006564145,0.05098792,0.00026563674,0.00032106263,0.02393064,0.008082541,0.8209362,0.08715012],"study_design_scores_gemma":[0.0012115716,0.0010267737,0.035626914,0.00039876654,0.00008664466,0.073539875,0.00095416576,0.0056967065,0.023010962,0.031123959,0.8271896,0.00013401944],"about_ca_topic_score_codex":0.0008387743,"about_ca_topic_score_gemma":0.0018477197,"teacher_disagreement_score":0.005613336,"about_ca_system_score_codex":0.00094138953,"about_ca_system_score_gemma":0.00043773418,"threshold_uncertainty_score":0.010115147},"labels":[],"label_agreement":null},{"id":"W3049616059","doi":"10.1172/jci139741","title":"Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":257,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Robert Packard Center for ALS Research, Johns Hopkins University; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institutes of Health; UK Dementia Research Institute; University College London; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; New York Genome Center; ALS Association; Alzheimer's Society; Tow Foundation; Motor Neurone Disease Association; Johns Hopkins University; Medical Research Council; Mayo Clinic; National Institute on Aging; Target ALS; University College London Hospitals NHS Foundation Trust; Rosetrees Trust; U.S. Department of Defense","keywords":"Frontotemporal dementia; Frontotemporal lobar degeneration; Stathmin; Progressive supranuclear palsy; Dementia; Tauopathy; Pathological; Pathology; Tau protein; Biology; Neurodegeneration; Medicine; Disease; Alzheimer's disease; Genetics; Phosphorylation","score_opus":0.18521537845934716,"score_gpt":0.4231322452937557,"score_spread":0.23791686683440855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3049616059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99472946,0.002250333,0.00066538656,0.00005980081,0.000015333108,0.000008493991,0.0013144102,0.000049519433,0.000907267],"genre_scores_gemma":[0.99675155,0.00044881066,0.0007284708,0.000084979525,0.000014614837,0.000013673861,0.0012911875,0.000008278421,0.00065851375],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99983513,0.000013455218,0.000018119656,0.00005442741,0.00005549095,0.000023247201],"domain_scores_gemma":[0.9998068,0.00003002777,0.00007906173,0.0000146252,0.000037470803,0.000032127777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034393897,0.0003533766,0.0002992452,0.0009569391,0.00028732733,0.00040658977,0.00016506466,0.00043537837,0.0016577061],"category_scores_gemma":[0.00033353816,0.00015817989,0.00029620723,0.00046896774,0.00030301962,0.00020534867,0.00025792452,0.00032341306,0.00029443062],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028757919,0.000087951485,0.3499129,0.00048310298,0.0003780112,0.0015238806,0.0005268093,0.0006874442,0.61326015,0.00025897162,0.0011621355,0.028842788],"study_design_scores_gemma":[0.000020303542,0.0002721464,0.9644101,0.00005085089,0.00014705524,0.002327855,0.00019315213,0.0014349899,0.02905716,0.00050721987,0.0015607581,0.000018308328],"about_ca_topic_score_codex":0.0016683032,"about_ca_topic_score_gemma":0.0031306855,"teacher_disagreement_score":0.0016683032,"about_ca_system_score_codex":0.00033655632,"about_ca_system_score_gemma":0.000113133785,"threshold_uncertainty_score":0.0055455565},"labels":[],"label_agreement":null},{"id":"W3080515671","doi":"10.1172/jci131799","title":"Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Army Medical University; Legacy Heritage Fund","keywords":"Autoimmunity; Immunology; Graft-versus-host disease; Immune tolerance; Transplantation; Immune system; Biology; Medicine; Internal medicine","score_opus":0.0422690983918273,"score_gpt":0.3275281912207282,"score_spread":0.2852590928289009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080515671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953094,0.00085405365,0.0022131603,0.000081108126,0.000052877414,0.000056587563,0.0003245962,0.00020237477,0.0009057257],"genre_scores_gemma":[0.9929222,0.0009922859,0.002901901,0.0001254027,0.00004387849,0.00009683239,0.00057219143,0.000054332035,0.0022908251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99972886,0.000052910837,0.00003542945,0.0000629834,0.000062979074,0.000056947505],"domain_scores_gemma":[0.99968565,0.00003368012,0.00012748085,0.00004605977,0.000013941986,0.000093217546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003404605,0.0005874313,0.00047057003,0.00048154686,0.00017414305,0.0003847085,0.00031873983,0.00042303928,0.0012477409],"category_scores_gemma":[0.00013831856,0.00022946097,0.00029970577,0.0001603613,0.0002451403,0.00022267034,0.00023618308,0.0012011165,0.00022248783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001092634,0.00043094996,0.00054165005,0.00008292779,0.000027758133,0.00012089108,0.000036591253,0.00027114124,0.99251974,0.0002138129,0.00010654113,0.0045552365],"study_design_scores_gemma":[0.00079960824,0.008916083,0.012994108,0.00006851068,0.00016405669,0.0018258933,0.00008937676,0.00475731,0.9631565,0.0003046547,0.006896056,0.000027735436],"about_ca_topic_score_codex":0.00024447768,"about_ca_topic_score_gemma":0.00042453723,"teacher_disagreement_score":0.0012477409,"about_ca_system_score_codex":0.0002192185,"about_ca_system_score_gemma":0.00024553938,"threshold_uncertainty_score":0.0041741133},"labels":[],"label_agreement":null},{"id":"W3080643008","doi":"10.1172/jci138728","title":"Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"George & Fay Yee Centre for Healthcare Innovation; CenterLine (Canada); Public Health Agency of Canada; University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; NIH Office of the Director; Canadian Institutes of Health Research; Public Health Agency of Canada; National Institutes of Health; National Center for Research Resources; Public Health Agency; University of Wisconsin-Madison","keywords":"Protease; Virology; Cleavage (geology); Medicine; Biology; Microbiology; Enzyme; Biochemistry","score_opus":0.06407003859074742,"score_gpt":0.34997761551151696,"score_spread":0.2859075769207695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080643008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99833435,0.0005554975,0.0006765243,0.00006908166,0.0000125416045,0.000017506636,0.00004419169,0.000035559988,0.0002547447],"genre_scores_gemma":[0.9973802,0.000408879,0.0011953714,0.000092738985,0.000017156135,0.000019684803,0.00015627478,0.0000071729014,0.0007225365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990916,0.000016796512,0.0000055547553,0.000017909575,0.000017558414,0.000033021202],"domain_scores_gemma":[0.9999167,0.000016817106,0.000020030548,0.000010813216,0.00001133998,0.000024308236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018019116,0.0002478524,0.00028896052,0.00023288812,0.00012279255,0.00022264848,0.000114315706,0.00029623572,0.0005698734],"category_scores_gemma":[0.00028740952,0.00007565985,0.00015677608,0.000056044013,0.00020977725,0.000107555,0.00013249199,0.000430259,0.00012019973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032036225,0.0001255483,0.0016499858,0.000054127107,0.000013070997,0.000059362137,0.000029140883,0.00024535798,0.9883747,0.000054799053,0.000091904876,0.008981693],"study_design_scores_gemma":[0.00016075668,0.011363114,0.07895399,0.00011036817,0.00010616271,0.0013370945,0.00024163479,0.010090402,0.8890368,0.00050858816,0.008063508,0.000027551996],"about_ca_topic_score_codex":0.0007463977,"about_ca_topic_score_gemma":0.0012673899,"teacher_disagreement_score":0.0007463977,"about_ca_system_score_codex":0.0001379437,"about_ca_system_score_gemma":0.00026085012,"threshold_uncertainty_score":0.0019064546},"labels":[],"label_agreement":null},{"id":"W3087272604","doi":"10.1172/jci139700","title":"The ABO histo-blood group, endothelial activation, and acute respiratory distress syndrome risk in critical illness","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Genentech; National Institutes of Health; Perelman School of Medicine, University of Pennsylvania; China Scholarship Council; Marcus Foundation; University of Pennsylvania","keywords":"Medicine; ARDS; ABO blood group system; Disseminated intravascular coagulation; Hypoxemia; Pulmonary edema; Immunology; Endothelial dysfunction; Internal medicine; Lung","score_opus":0.1583511832275546,"score_gpt":0.4223484758593966,"score_spread":0.263997292631842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3087272604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99663585,0.0015232465,0.00021761196,0.0002869721,0.000031622112,0.000010974723,0.0008620007,0.000004675605,0.0004271276],"genre_scores_gemma":[0.99892753,0.00024361795,0.00016980532,0.000048584756,0.000040262512,0.000011991169,0.00045113874,0.0000018764554,0.0001052278],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997197,0.00008895667,0.000025228557,0.00006517631,0.00004297432,0.00005789261],"domain_scores_gemma":[0.99877983,0.00021054983,0.00053851434,0.00005994584,0.00009862185,0.0003125537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005960907,0.00032219806,0.0001864683,0.00039149445,0.00028745335,0.00041910802,0.0002862244,0.00039362267,0.0018143643],"category_scores_gemma":[0.0015572469,0.00010199934,0.00033470942,0.00057523476,0.00017778242,0.00022641322,0.0003928098,0.0007261913,0.00010227313],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017289085,0.000017628445,0.99777704,0.00001605365,0.00007205981,0.000033511278,0.000014587285,0.00005472833,0.00031027893,0.000030927255,0.0001890157,0.0013112208],"study_design_scores_gemma":[0.0000057155567,0.00004326172,0.9994492,0.0000061409273,0.000023161807,0.00007278535,0.000022103133,0.00016229946,0.000044948403,0.000042788706,0.00012553915,0.0000018679414],"about_ca_topic_score_codex":0.0031642728,"about_ca_topic_score_gemma":0.0025218127,"teacher_disagreement_score":0.0031642728,"about_ca_system_score_codex":0.00022275251,"about_ca_system_score_gemma":0.00029262976,"threshold_uncertainty_score":0.0062916875},"labels":[],"label_agreement":null},{"id":"W3092108146","doi":"10.1172/jci137265","title":"Landscape of coordinated immune responses to H1N1 challenge in humans","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Human Genome Research Institute; Sanofi Pasteur; Juno Therapeutics; Stanford Bio-X; National Institutes of Health; Hamilton Health Sciences Foundation; Canadian Institutes of Health Research; Parker Institute for Cancer Immunotherapy; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Kenneth Rainin Foundation; Novavax; Celgene; U.S. Department of Defense; Silicon Valley Community Foundation; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi; Cancer Research Institute; National Heart, Lung, and Blood Institute; Pfizer; Bill and Melinda Gates Foundation; Cancer Research UK; Doris Duke Charitable Foundation; U.S. Food and Drug Administration; National Institute of General Medical Sciences; Burroughs Wellcome Fund; National Science Foundation","keywords":"Immune system; Mass cytometry; CD38; Virus; Immunology; Biology; T cell; Cell; Influenza A virus; Monocyte; Virology; Cell biology; Phenotype; Genetics; Stem cell","score_opus":0.08494406879469951,"score_gpt":0.33989440638050816,"score_spread":0.25495033758580865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092108146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974136,0.0005573246,0.00086239574,0.00009089783,0.0000045178954,0.000011886201,0.00020614131,0.00001980483,0.00083350245],"genre_scores_gemma":[0.9990085,0.00017345557,0.0003864897,0.000056202844,0.000008520261,0.000011526461,0.00014572489,0.0000028285358,0.00020676138],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99986744,0.000032370233,0.000004918248,0.000050792434,0.000022618764,0.000021852098],"domain_scores_gemma":[0.999887,0.000019480427,0.00003949919,0.000011061253,0.00001979165,0.000023159206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020089725,0.00009685811,0.00025166286,0.0002727253,0.00019900106,0.00034467783,0.00009936626,0.00020761587,0.00049175095],"category_scores_gemma":[0.00030002254,0.00011272201,0.00009193348,0.00014903347,0.00020625426,0.00015612104,0.00019187115,0.00017834424,0.0001223448],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009940597,0.00014760293,0.54257447,0.00009981783,0.00022279305,0.0004149457,0.00047615197,0.0025151616,0.39349458,0.00042726012,0.0012016245,0.05743153],"study_design_scores_gemma":[0.0000058543897,0.00034955228,0.9909869,0.000008738386,0.000028811428,0.00051204953,0.0002659682,0.0022968787,0.003925197,0.0004240435,0.0011861637,0.000009815794],"about_ca_topic_score_codex":0.000813926,"about_ca_topic_score_gemma":0.0015139017,"teacher_disagreement_score":0.000813926,"about_ca_system_score_codex":0.00017820485,"about_ca_system_score_gemma":0.00014296375,"threshold_uncertainty_score":0.0016450286},"labels":[],"label_agreement":null},{"id":"W3092471114","doi":"10.1172/jci140424","title":"Hypothalamic REV-ERB nuclear receptors control diurnal food intake and leptin sensitivity in diet-induced obese mice","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; JPB Foundation; University of Pennsylvania; Eli Lilly and Company; Pfizer; American Diabetes Association","keywords":"Leptin; Endocrinology; Internal medicine; Hypothalamus; Leptin receptor; Arcuate nucleus; Obesity; Food intake; Circadian rhythm; Biology; Arc (geometry); Nucleus; Receptor; Medicine; Neuroscience","score_opus":0.1055160968740082,"score_gpt":0.318158460733943,"score_spread":0.2126423638599348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092471114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924918,0.0013484561,0.003200173,0.00018473736,0.000045288507,0.000034647815,0.0012416627,0.0002498576,0.0012034194],"genre_scores_gemma":[0.9840201,0.0013975836,0.0049955975,0.00021001816,0.000019665595,0.00017279049,0.0014172927,0.00027006058,0.007496853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999716,0.00004983022,0.000032770276,0.00008423639,0.000055708508,0.00006150178],"domain_scores_gemma":[0.99972016,0.000015063919,0.0001369325,0.000036304376,0.000018133751,0.00007345192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025287148,0.00048265234,0.00037746207,0.0008037642,0.000223106,0.00043365153,0.0003803808,0.00036716735,0.0015939927],"category_scores_gemma":[0.00014114058,0.00037895367,0.00034361513,0.00023176573,0.00053345866,0.00029247388,0.00029349537,0.0009530826,0.00052545057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035623153,0.00004772686,0.00038831742,0.000017327066,0.000006552116,0.000041920484,0.000025340534,0.000034174616,0.9977156,0.00010103304,0.00004413529,0.0012217329],"study_design_scores_gemma":[0.00017705813,0.0008238858,0.04253014,0.000041607316,0.00007786677,0.00076435483,0.00022623199,0.0013821408,0.9481074,0.00026134576,0.005571512,0.00003635456],"about_ca_topic_score_codex":0.0007743568,"about_ca_topic_score_gemma":0.0019133086,"teacher_disagreement_score":0.0015939927,"about_ca_system_score_codex":0.0003929482,"about_ca_system_score_gemma":0.00022887868,"threshold_uncertainty_score":0.00533247},"labels":[],"label_agreement":null},{"id":"W3098436432","doi":"10.1172/jci128650","title":"The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Montreal Clinical Research Institute; Hamilton Health Sciences; Population Health Research Institute","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Amgen Canada; Amgen; Fondation Leducq; McMaster University; Rutgers Cancer Institute of New Jersey; Heart and Stroke Foundation of Canada","keywords":"Endoplasmic reticulum; PCSK9; Unfolded protein response; Liver injury; Proprotein convertase; Kexin; Biology; Endocrinology; Liver disease; Loss function; Internal medicine; Cell biology; Cholesterol; LDL receptor; Medicine; Lipoprotein; Phenotype; Biochemistry; Gene","score_opus":0.03500007966507407,"score_gpt":0.3028957084122491,"score_spread":0.26789562874717504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098436432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977851,0.00030771684,0.0006369104,0.00012758494,0.000015113325,0.000007906579,0.00048783247,0.000036354868,0.0005954095],"genre_scores_gemma":[0.99697113,0.00024516165,0.000536524,0.000053462525,0.000005721217,0.000004573762,0.00043317513,0.0000130131175,0.0017371794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999112,0.0000087308445,0.000008351242,0.000025006144,0.000026714397,0.000020031775],"domain_scores_gemma":[0.9999337,0.000006031659,0.000018573732,0.0000069864054,0.000011199659,0.000023477987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009658446,0.00038578126,0.00016847401,0.00023864543,0.00025531783,0.000213076,0.00017444717,0.00020199978,0.0020319992],"category_scores_gemma":[0.000087021035,0.000088494606,0.00025837863,0.00019808144,0.00029153595,0.000071365976,0.0001845319,0.00028225087,0.0001698959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006875465,0.000037658254,0.0055811023,0.000041932683,0.000048139234,0.0004858692,0.000047326557,0.00013324604,0.9888842,0.00012074764,0.00020287796,0.0037294617],"study_design_scores_gemma":[0.00012685098,0.0008674067,0.32863408,0.000018124243,0.00025466687,0.004156009,0.0002550526,0.0018560207,0.6523469,0.00014196397,0.011307034,0.00003581465],"about_ca_topic_score_codex":0.028973013,"about_ca_topic_score_gemma":0.04018017,"teacher_disagreement_score":0.028973013,"about_ca_system_score_codex":0.0006168063,"about_ca_system_score_gemma":0.00052048004,"threshold_uncertainty_score":0.057608724},"labels":[],"label_agreement":null},{"id":"W3103217889","doi":"10.1172/jci138532","title":"Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Eating Disorders and Behaviors","field":"Psychology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University","funders":"Canadian Institutes of Health Research; Université Pierre et Marie Curie; National Institute of Mental Health; Centre National de la Recherche Scientifique; Fonds de Recherche du Québec - Santé; Fondation de France; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Acetylcholine; Striatum; Cholinergic; Dopamine; Psychology; Neuroscience; Glutamate receptor; Endocrinology; Internal medicine; Biology; Medicine","score_opus":0.12702707016754816,"score_gpt":0.3861936196901181,"score_spread":0.25916654952256996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3103217889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986487,0.0006146229,0.00022825069,0.000039297593,0.000004225389,0.0000052181667,0.000028812137,0.00002064845,0.00041038054],"genre_scores_gemma":[0.999065,0.000374054,0.00022162875,0.000029773148,0.0000029359944,0.0000041421576,0.000052064734,0.0000021904457,0.0002482382],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99997044,0.000006829875,0.000002845381,0.0000074314275,0.0000063828734,0.0000059772565],"domain_scores_gemma":[0.9999052,0.000007695366,0.000034309247,0.0000060180364,0.0000071684312,0.000039615537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000063679094,0.00031898395,0.0002505969,0.00022836946,0.00012487822,0.00017837333,0.000098210876,0.00019179507,0.0008808966],"category_scores_gemma":[0.0001029955,0.00010902201,0.00012662905,0.000097413315,0.00027235915,0.000080294165,0.0002186159,0.00039774302,0.00009245269],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002065654,0.00044071,0.078197904,0.00016284143,0.00016889734,0.0033944005,0.00013681377,0.00021207276,0.8945265,0.00023188599,0.00024837742,0.020214021],"study_design_scores_gemma":[0.00010279336,0.0027878957,0.9065059,0.000047824007,0.00013784925,0.013777874,0.00028443531,0.0015754661,0.0734267,0.00039791912,0.00093805447,0.000017180248],"about_ca_topic_score_codex":0.00065982994,"about_ca_topic_score_gemma":0.0019614235,"teacher_disagreement_score":0.0008808966,"about_ca_system_score_codex":0.00016066972,"about_ca_system_score_gemma":0.00013707935,"threshold_uncertainty_score":0.0029469132},"labels":[],"label_agreement":null},{"id":"W3112963515","doi":"10.1172/jci139927","title":"Biomarkers of inflammation and repair in kidney disease progression","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Kidney Injury Research","field":"Medicine","cited_by":185,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; Akebia Therapeutics","keywords":"Kidney disease; Medicine; Acute kidney injury; Inflammation; Disease; Kidney; Intensive care medicine; Bioinformatics; Pathology; Internal medicine; Biology","score_opus":0.11045748687184008,"score_gpt":0.4407257322499085,"score_spread":0.3302682453780684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112963515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94010586,0.051368687,0.003163676,0.0008795153,0.00017426258,0.00013345678,0.0020539956,0.000090829606,0.0020297007],"genre_scores_gemma":[0.99326354,0.0030507697,0.0020584436,0.00016270428,0.0001315125,0.00008739075,0.0005156485,0.0000033005308,0.0007267563],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990349,0.00039556815,0.000116333205,0.00015245393,0.0001804297,0.000120289806],"domain_scores_gemma":[0.99815124,0.00022302996,0.0011957252,0.00006347152,0.00019336345,0.00017313608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016455734,0.0007097157,0.0006056795,0.001130486,0.0002622736,0.001114727,0.00038272495,0.000561027,0.001626309],"category_scores_gemma":[0.0017581041,0.000160232,0.00042201497,0.001072714,0.00029225336,0.0004826799,0.00063814415,0.0006276461,0.00018250525],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012457361,0.00023095822,0.9491625,0.00041377838,0.0004964041,0.00016004038,0.000103458005,0.0008364031,0.0061338195,0.0003792077,0.0010580751,0.039779667],"study_design_scores_gemma":[0.00009838736,0.0009712587,0.98203367,0.00021076637,0.00037969224,0.0009986463,0.00013849697,0.003065934,0.0050337277,0.0014017879,0.0056253783,0.000042394116],"about_ca_topic_score_codex":0.0013570867,"about_ca_topic_score_gemma":0.0015912191,"teacher_disagreement_score":0.0016455734,"about_ca_system_score_codex":0.0005625501,"about_ca_system_score_gemma":0.000652615,"threshold_uncertainty_score":0.008702755},"labels":[],"label_agreement":null},{"id":"W3113357120","doi":"10.1172/jci131517","title":"Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Direction Générale de l’offre de Soins; Institute of Cancer Research; Institut National Du Cancer; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; Consortium canadien en neurodégénérescence associée au vieillissement; CNIB","keywords":"Colorectal cancer; Homeostasis; Medicine; Cancer research; Internal medicine; Oncology; Cancer; Biology","score_opus":0.09012348545282048,"score_gpt":0.3795079644940478,"score_spread":0.2893844790412273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113357120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7883836,0.20309235,0.0022648934,0.00073519343,0.000095002375,0.000032126063,0.0031317964,0.00007992544,0.002185113],"genre_scores_gemma":[0.98190373,0.0153977545,0.00069379853,0.0001393085,0.00006708323,0.000020063628,0.0014175223,0.000011733128,0.00034904917],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.999608,0.00011680804,0.00003714778,0.0001254021,0.00007729949,0.00003536383],"domain_scores_gemma":[0.9993248,0.00018378465,0.00028493395,0.00005690104,0.000077595505,0.00007200296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007714108,0.00024365414,0.0006634902,0.0014503746,0.00030689954,0.00069336983,0.00018184571,0.00024343796,0.0006239866],"category_scores_gemma":[0.0012568561,0.00016663117,0.0005204977,0.0021470697,0.00026946477,0.00032482983,0.00027691378,0.00032134526,0.00011433763],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004336816,0.00008405509,0.83067995,0.002222952,0.0057709487,0.0006085627,0.00017245818,0.0017937612,0.07074768,0.0009789345,0.002052934,0.08055092],"study_design_scores_gemma":[0.000098157376,0.0003686519,0.96222883,0.00018802115,0.0028943093,0.0012071348,0.00015551924,0.002113863,0.009930765,0.0013176368,0.019468786,0.000028357728],"about_ca_topic_score_codex":0.0017508569,"about_ca_topic_score_gemma":0.0024664926,"teacher_disagreement_score":0.0017508569,"about_ca_system_score_codex":0.00038888791,"about_ca_system_score_gemma":0.0004391307,"threshold_uncertainty_score":0.0040796995},"labels":[],"label_agreement":null},{"id":"W3114353478","doi":"10.1172/jci137681","title":"Evolutionary conservation of human ketodeoxynonulosonic acid production is independent of sialoglycan biosynthesis","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Glycan; Sialic acid; Biochemistry; Biology; Mannose; Antibody; Biosynthesis; Enzyme; Glycosylation; Glycoprotein; Genetics","score_opus":0.10223160049854933,"score_gpt":0.37471423415757277,"score_spread":0.2724826336590234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3114353478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940812,0.0012409842,0.002168448,0.00005979444,0.00001025327,0.000012035947,0.0002064293,0.00002691887,0.0021938258],"genre_scores_gemma":[0.99381787,0.0011918063,0.0025487058,0.00005998625,0.000012004849,0.000012085847,0.0005972129,0.000013311126,0.0017471185],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998971,0.000016376678,0.0000070338488,0.000046461315,0.000017701112,0.000015277048],"domain_scores_gemma":[0.999918,0.000010483361,0.000022105909,0.000017343204,0.000013038345,0.000019153122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017108537,0.00014397416,0.00015826136,0.00030808477,0.00016454137,0.00032168117,0.000118750024,0.00019423649,0.00064906565],"category_scores_gemma":[0.00011330004,0.000099306024,0.00017806591,0.0002275789,0.00019275352,0.0001616378,0.00026176596,0.00023063224,0.00020486698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031662948,0.000018072835,0.017108407,0.00004957181,0.000043043725,0.0003859,0.00011489673,0.00015322874,0.96611696,0.00056186446,0.000060518614,0.015070906],"study_design_scores_gemma":[0.000043112308,0.0010552951,0.64456546,0.000051736788,0.00014714916,0.008255182,0.00029415675,0.0020691806,0.30736816,0.0009772672,0.0351183,0.000054966804],"about_ca_topic_score_codex":0.0004512061,"about_ca_topic_score_gemma":0.0005045468,"teacher_disagreement_score":0.00064906565,"about_ca_system_score_codex":0.00016947652,"about_ca_system_score_gemma":0.00018759824,"threshold_uncertainty_score":0.0021713376},"labels":[],"label_agreement":null},{"id":"W3118504306","doi":"10.1172/jci142239","title":"The discovery of insulin revisited: lessons for the modern era","year":2021,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Diabetes Management and Research","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Diabetes Canada","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Insulin; Scientific discovery; Medicine; Engineering ethics; Psychology; Internal medicine; Engineering; Cognitive science","score_opus":0.3239259357180677,"score_gpt":0.5193490346202676,"score_spread":0.1954230989021999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118504306","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00004149541,0.9949004,0.00004167892,0.0034150972,0.00091223326,5.117875e-7,0.0000026574758,0.0000025454265,0.0006834661],"genre_scores_gemma":[0.0012222872,0.99215925,0.00009352669,0.003884773,0.001873996,0.0000027750389,0.000007948237,0.0000031624434,0.00075236533],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992003,0.00023406628,0.000072927425,0.000100509875,0.00028613873,0.00010608662],"domain_scores_gemma":[0.9985661,0.00094726385,0.00008325748,0.00004153509,0.00022633221,0.00013569192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021860807,0.0010297465,0.0011994416,0.0021604903,0.0008611197,0.0031071764,0.000999944,0.003332742,0.003440469],"category_scores_gemma":[0.0032870767,0.00028770397,0.0005773253,0.002355484,0.0038123617,0.0071553662,0.0018619726,0.008000556,0.0014549778],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002461401,0.00009633324,0.0002187936,0.010673659,0.00007454954,0.00059100304,0.0008670397,0.0003575852,0.0009519435,0.12411648,0.181532,0.68027455],"study_design_scores_gemma":[0.000011344275,0.00003750388,0.00018221534,0.0023269805,0.000014572507,0.0004608795,0.00020455138,0.000035731307,0.00010580084,0.013925774,0.982682,0.00001271923],"about_ca_topic_score_codex":0.002811082,"about_ca_topic_score_gemma":0.0042191427,"teacher_disagreement_score":0.003440469,"about_ca_system_score_codex":0.0033882563,"about_ca_system_score_gemma":0.0034686364,"threshold_uncertainty_score":0.024583638},"labels":[],"label_agreement":null},{"id":"W3118686664","doi":"10.1172/jci131698","title":"Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"PTEN; Biology; Tensin; DNA damage; Stem cell; Cell biology; Haematopoiesis; Hematopoietic stem cell; Genome instability; Senescence; Cancer research; PI3K/AKT/mTOR pathway; Genetics; Signal transduction; DNA","score_opus":0.06054323323607035,"score_gpt":0.3451578053508976,"score_spread":0.2846145721148272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118686664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944079,0.0016395816,0.002614059,0.00012891671,0.000015328354,0.000021345013,0.0001010389,0.00006553581,0.001006297],"genre_scores_gemma":[0.99807596,0.000529908,0.0008455095,0.000022206646,0.0000092918945,0.0000142467625,0.000056306802,0.000005543715,0.0004409739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983704,0.000028561513,0.000015683707,0.000035679972,0.00004289722,0.000040058265],"domain_scores_gemma":[0.99988294,0.000013312801,0.000046792866,0.000012207161,0.000007272377,0.00003740121],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035186976,0.00032821327,0.00021251682,0.0003667278,0.0001729572,0.0003915928,0.00023618873,0.00019679527,0.000622415],"category_scores_gemma":[0.00017069366,0.00014132872,0.00013984034,0.0001679678,0.00047026353,0.0003819089,0.00037311492,0.0002927375,0.0001166127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035432112,0.000030471287,0.0018790191,0.00004234346,0.000008628518,0.0002506881,0.000029972136,0.00020523046,0.9922576,0.00079149235,0.00003702975,0.0041132197],"study_design_scores_gemma":[0.00007462136,0.0011398584,0.04469584,0.0000098815435,0.000070100956,0.0015695342,0.00012162456,0.0031803928,0.9448278,0.0016433463,0.0026492523,0.000017813567],"about_ca_topic_score_codex":0.00008337057,"about_ca_topic_score_gemma":0.00018682281,"teacher_disagreement_score":0.000622415,"about_ca_system_score_codex":0.00016065165,"about_ca_system_score_gemma":0.0002289664,"threshold_uncertainty_score":0.0020822287},"labels":[],"label_agreement":null},{"id":"W3119978264","doi":"10.1172/jci144964","title":"Location is everything when it comes to megakaryocyte function","year":2021,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Megakaryocyte; Platelet; Bone marrow; Immunology; Biology; Phenotype; Population; Immune system; Cell biology; Lung; Gene; Genetics; Haematopoiesis; Medicine; Internal medicine; Stem cell","score_opus":0.11973210407246207,"score_gpt":0.37744904164441245,"score_spread":0.25771693757195036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3119978264","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010563417,0.0142646795,0.00027003005,0.9228285,0.05628843,0.00000817602,0.0000495423,0.00004852336,0.0051857266],"genre_scores_gemma":[0.021302072,0.02404457,0.0006408315,0.59038395,0.34963283,0.000027271682,0.000059578593,0.00004587013,0.013863043],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988342,0.00035471396,0.00013630118,0.00015356031,0.0003969016,0.00012435243],"domain_scores_gemma":[0.99726,0.0014453316,0.00019012837,0.00012985105,0.0006501921,0.00032461755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011344997,0.00037858446,0.00082539243,0.00038324558,0.0016620766,0.0021105793,0.0010480148,0.011341266,0.0036630733],"category_scores_gemma":[0.005875579,0.00030930733,0.0005020445,0.00031678253,0.0023165704,0.0020333922,0.00043100078,0.015833415,0.004166733],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009817121,0.000040908864,0.0010553394,0.00012399178,0.000017606733,0.0025988654,0.00014064723,0.00006912346,0.0011135007,0.0034962704,0.95210904,0.039136574],"study_design_scores_gemma":[0.000057446454,0.00008059313,0.0017100783,0.00026345853,0.000026247406,0.0053564957,0.0003673238,0.00023459116,0.000740429,0.010494108,0.98063654,0.00003275692],"about_ca_topic_score_codex":0.0018497048,"about_ca_topic_score_gemma":0.0033854705,"teacher_disagreement_score":0.011341266,"about_ca_system_score_codex":0.0020947482,"about_ca_system_score_gemma":0.001031311,"threshold_uncertainty_score":0.015198529},"labels":[],"label_agreement":null},{"id":"W3120671396","doi":"10.1172/jci140903","title":"Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; University Health Network; University of Toronto; London Health Sciences Centre; Western University","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Amyloid (mycology); Laser capture microdissection; Amyloidosis; Biology; Repressor; Epigenetics; Cancer research; Molecular biology; Cell biology; Gene; Gene expression; Genetics; Pathology; Medicine","score_opus":0.07414205495502421,"score_gpt":0.3658063727677357,"score_spread":0.2916643178127115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120671396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941062,0.00037290764,0.003410162,0.00021302093,0.000030590192,0.000043863496,0.0006374501,0.0003295144,0.0008562863],"genre_scores_gemma":[0.9900067,0.00038074332,0.0036489943,0.00017402567,0.000025018753,0.00010800359,0.0008479429,0.00015202997,0.00465654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994708,0.000102532715,0.00006960217,0.00013690526,0.00010168514,0.00011858315],"domain_scores_gemma":[0.9992519,0.00015626133,0.00024160167,0.0000665927,0.000030456831,0.0002531324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034036266,0.0005887016,0.00036811715,0.0010439561,0.0002460247,0.00044011115,0.0004244209,0.0007579319,0.0017443997],"category_scores_gemma":[0.00031571006,0.00048611706,0.0004963195,0.00029166188,0.0006651325,0.00023911576,0.00044362806,0.0011787646,0.0003846762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058130716,0.00018448348,0.00056403165,0.00002498742,0.000018084322,0.00027667222,0.000039570714,0.00009719613,0.99678314,0.00024732898,0.000081558894,0.0011016716],"study_design_scores_gemma":[0.00020150776,0.0013480174,0.011304597,0.000022878037,0.00005763662,0.0012200666,0.000104467705,0.002549335,0.9807426,0.00029762406,0.002131822,0.00001936635],"about_ca_topic_score_codex":0.0006726133,"about_ca_topic_score_gemma":0.0012657781,"teacher_disagreement_score":0.0017443997,"about_ca_system_score_codex":0.0005298864,"about_ca_system_score_gemma":0.00031507472,"threshold_uncertainty_score":0.0058355927},"labels":[],"label_agreement":null},{"id":"W3122105450","doi":"10.1172/jci145837","title":"Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with gastrointestinal dysmotility in humans","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital gastrointestinal and neural anomalies","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Institut des maladies génétiques Imagine; Agence Nationale de la Recherche; Canadian Centre for Applied Research in Cancer Control","keywords":"Biology; ErbB; Interstitial cell of Cajal; Enteric nervous system; Exome sequencing; Genetics; Pathology; Gene; Mutation; Immunology; Medicine; Endocrinology; Immunohistochemistry","score_opus":0.07000040456509847,"score_gpt":0.32276584853301066,"score_spread":0.2527654439679122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122105450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99308664,0.0024393117,0.0015281056,0.00007357883,0.000019992895,0.00002053887,0.00080037926,0.00011594898,0.0019155272],"genre_scores_gemma":[0.9957386,0.0015609204,0.0013919651,0.00007328508,0.0000094607285,0.000013785574,0.0005271549,0.000020942074,0.00066372653],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99987864,0.00001819166,0.000013906894,0.00004789862,0.00002757294,0.000013776029],"domain_scores_gemma":[0.9999466,0.000007647981,0.000021330123,0.000008417611,0.000004076656,0.000011940652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079895166,0.0005299066,0.0002284361,0.0005473882,0.00018135153,0.00018617358,0.00013310855,0.00024239409,0.0013659311],"category_scores_gemma":[0.00019105019,0.00013943743,0.00023254998,0.00033161897,0.00019762339,0.00007822008,0.00025992512,0.00018716122,0.00036186608],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051499665,0.000068322304,0.048892263,0.00018926038,0.00014024,0.035625886,0.00021192014,0.00025465045,0.8893039,0.0005220905,0.0007811128,0.023495361],"study_design_scores_gemma":[0.00007071384,0.00049368775,0.655336,0.000116399875,0.00035988243,0.22734931,0.00029304382,0.0013677103,0.09713148,0.0005298194,0.01690907,0.00004285519],"about_ca_topic_score_codex":0.0007279699,"about_ca_topic_score_gemma":0.0008174544,"teacher_disagreement_score":0.0013659311,"about_ca_system_score_codex":0.00013740023,"about_ca_system_score_gemma":0.000112163274,"threshold_uncertainty_score":0.004569471},"labels":[],"label_agreement":null},{"id":"W3123021082","doi":"10.1172/jci136737","title":"CC17 group B Streptococcus exploits integrins for neonatal meningitis development","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal and Maternal Infections","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Paris; Fonds d’Etudes et de Recherche du Corps Médical; Defence Research and Development Canada; Université Paris Descartes; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Meningitis; Streptococcus; Streptococcus agalactiae; Group B; Exploit; Neonatal meningitis; Group (periodic table); Microbiology; Medicine; Computer science; Immunology; Biology; Genetics; Bacteria; Pediatrics; Internal medicine; Chemistry; Escherichia coli; Computer security; Gene","score_opus":0.11484675054097997,"score_gpt":0.39701400324078373,"score_spread":0.28216725269980375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123021082","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98831356,0.006875027,0.0018491466,0.00017588171,0.000035761037,0.000026412174,0.00015285211,0.0000461007,0.002525102],"genre_scores_gemma":[0.9921272,0.004895016,0.0012600435,0.00006852368,0.00001110811,0.000031746593,0.00013300509,0.0000093011995,0.0014641301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998424,0.000041282055,0.000013683535,0.000018546443,0.000038820497,0.000045232966],"domain_scores_gemma":[0.99987566,0.000011929038,0.000050274357,0.000010240863,0.000018111907,0.00003369989],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019310285,0.0003541739,0.00018265392,0.00022804372,0.00012902878,0.00028094204,0.00014921861,0.00028744378,0.0009301321],"category_scores_gemma":[0.0002364102,0.00009358093,0.00017688643,0.00010578465,0.00019408154,0.00015802283,0.00027046318,0.00038616944,0.00021771873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002495224,0.0000392921,0.006747006,0.000109427376,0.000007691747,0.0012457393,0.00013659339,0.00006356473,0.9814811,0.0005862031,0.00019395383,0.009139835],"study_design_scores_gemma":[0.000030568313,0.0015234179,0.12245477,0.00014135778,0.00007772421,0.010718395,0.00085303857,0.0014056095,0.84255475,0.0004014665,0.019818673,0.000020273754],"about_ca_topic_score_codex":0.0008112272,"about_ca_topic_score_gemma":0.0010333975,"teacher_disagreement_score":0.0009301321,"about_ca_system_score_codex":0.00029925237,"about_ca_system_score_gemma":0.00037911627,"threshold_uncertainty_score":0.0031116009},"labels":[],"label_agreement":null},{"id":"W3123153443","doi":"10.1172/jci138267","title":"Impaired complex I repair causes recessive Leber’s hereditary optic neuropathy","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Lomonosov Moscow State University; Università di Bologna; Cardio-Pulmonary Institute; Ministero della Salute; E-Rare; Austrian Science Fund; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; Deutsche Forschungsgemeinschaft","keywords":"Medicine; Leber's hereditary optic neuropathy; Optic neuropathy; Genetics; Biology; Ophthalmology; Optic nerve","score_opus":0.09276138396998931,"score_gpt":0.36040034471470017,"score_spread":0.26763896074471083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123153443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99825805,0.0003984632,0.0005760152,0.00002432327,0.000004898396,0.000007143217,0.00008523858,0.00003821168,0.0006076719],"genre_scores_gemma":[0.99933535,0.00013429453,0.00023073974,0.000010574623,0.00000242282,0.0000019929098,0.000049730745,0.0000039732745,0.00023094316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998971,0.000015575895,0.000011167892,0.0000350182,0.000020934047,0.000020064015],"domain_scores_gemma":[0.9998678,0.000029043524,0.000057226014,0.0000086225,0.000007762386,0.000029506433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011343009,0.00057036924,0.00017034067,0.00032412485,0.00016082053,0.00012210262,0.000101309175,0.00019529668,0.0009669178],"category_scores_gemma":[0.00026569195,0.00012636957,0.000094618124,0.00016508214,0.00028931833,0.00010705862,0.00027051734,0.00014325426,0.00016711759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015311509,0.00012511402,0.120084755,0.00023348266,0.00010383501,0.03355718,0.0005325941,0.00048991974,0.8219042,0.00076445594,0.0006808069,0.019992474],"study_design_scores_gemma":[0.00018340547,0.0021008728,0.5910053,0.0000745709,0.00022625316,0.13071409,0.00045662594,0.0024837784,0.2654466,0.00073002337,0.006533508,0.000044979402],"about_ca_topic_score_codex":0.0010563305,"about_ca_topic_score_gemma":0.0015613062,"teacher_disagreement_score":0.0010563305,"about_ca_system_score_codex":0.00024446298,"about_ca_system_score_gemma":0.0001389568,"threshold_uncertainty_score":0.0032346249},"labels":[],"label_agreement":null},{"id":"W3123875011","doi":"10.1172/jci129433","title":"17β-estradiol and estrogen receptor α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Actelion Pharmaceuticals; National Center for Advancing Translational Sciences; University of California, San Diego; National Institutes of Health; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; U.S. Department of Defense; American Lung Association; Eli Lilly and Company; American Heart Association; Canadian Institutes of Health Research; School of Medicine, Indiana University; U.S. Department of Veterans Affairs","keywords":"Apelin; BMPR2; Internal medicine; Endocrinology; Agonist; Downregulation and upregulation; Pulmonary hypertension; Estrogen receptor; Receptor; Estrogen; Medicine; Biology; Bone morphogenetic protein","score_opus":0.06334375995272004,"score_gpt":0.35174768297916925,"score_spread":0.28840392302644924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123875011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846185,0.009740115,0.0028703953,0.00039227967,0.00007520701,0.000046350404,0.00025411602,0.000058772937,0.0019441565],"genre_scores_gemma":[0.9857227,0.006112417,0.0024342414,0.00029929433,0.0000689179,0.00008695536,0.00050876854,0.000019253504,0.0047475407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990153,0.000021244105,0.0000123571635,0.000016932041,0.000022781058,0.000025109352],"domain_scores_gemma":[0.99991965,0.000011088992,0.000021871232,0.000010473906,0.000008672133,0.000028313816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023254489,0.00028923916,0.00032971016,0.00026057148,0.0001237555,0.00020851537,0.00017974722,0.00027406533,0.0012544511],"category_scores_gemma":[0.00014576594,0.00016659829,0.0004113723,0.0001274359,0.0002219431,0.0002198628,0.00023535696,0.00050047657,0.00030071268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011833691,0.00014846971,0.0018483718,0.0001481598,0.000037455735,0.0003924525,0.00004146415,0.000081101374,0.98801583,0.0002482341,0.00009888168,0.007756233],"study_design_scores_gemma":[0.00037375637,0.0028516862,0.06543251,0.00003358089,0.00018096805,0.0021192133,0.00016472347,0.0009030118,0.9173002,0.00040220338,0.010223014,0.000015078925],"about_ca_topic_score_codex":0.00020786883,"about_ca_topic_score_gemma":0.00030171202,"teacher_disagreement_score":0.0012544511,"about_ca_system_score_codex":0.00009901242,"about_ca_system_score_gemma":0.00017097138,"threshold_uncertainty_score":0.0041965246},"labels":[],"label_agreement":null},{"id":"W3124533070","doi":"10.1172/jci140590","title":"Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Center for AIDS Research, University of Washington; Alberta Innovates; Styrelsen för Internationellt Utvecklingssamarbete; Public Health Agency; Yerkes National Primate Research Center, Emory University; National Institutes of Health; American Liver Foundation; Public Health Agency of Canada; Université de Montréal; Emory University","keywords":"Virology; Cell; Virus; Biology; Follicular phase; Immunology; Genetics","score_opus":0.057182549782053595,"score_gpt":0.30906102829874704,"score_spread":0.2518784785166934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124533070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983292,0.00054655,0.00030996252,0.00001947844,0.000007118665,0.000015055677,0.000105072344,0.000033376527,0.0006342335],"genre_scores_gemma":[0.99861705,0.00014690019,0.00026819427,0.00003354096,0.000013758541,0.000014222873,0.00015578352,0.000007023129,0.0007433851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998228,0.000031871517,0.000010203141,0.000039271712,0.00002819091,0.00006755293],"domain_scores_gemma":[0.999864,0.000025144136,0.000023335613,0.000014765625,0.000025567782,0.000047156456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002330563,0.00022855375,0.00019277741,0.00033162115,0.0001436908,0.0003696164,0.000107336775,0.00021913616,0.0019907989],"category_scores_gemma":[0.00027498402,0.00013044587,0.000120765086,0.000115524075,0.00015000837,0.00019353288,0.00023947877,0.0004184477,0.00043200076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044877763,0.000112189,0.0174326,0.000057827823,0.000009948835,0.0001729157,0.0001602112,0.000077750046,0.9732624,0.00009507012,0.00018690136,0.007983414],"study_design_scores_gemma":[0.00013882598,0.0026186446,0.5223934,0.000043128966,0.0000708417,0.001917524,0.00054618815,0.0030680208,0.46036515,0.00035642972,0.00845806,0.000023766002],"about_ca_topic_score_codex":0.00040428873,"about_ca_topic_score_gemma":0.0005675339,"teacher_disagreement_score":0.0019907989,"about_ca_system_score_codex":0.00013780448,"about_ca_system_score_gemma":0.00013685705,"threshold_uncertainty_score":0.0066598654},"labels":[],"label_agreement":null},{"id":"W3126232165","doi":"10.1172/jci143011","title":"Residual β cell function in long-term type 1 diabetes associates with reduced incidence of hypoglycemia","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Public Health Ontario; University of Toronto","funders":"Division of Diabetes, Endocrinology, and Metabolic Diseases; National Eye Institute; National Institute of Diabetes and Digestive and Kidney Diseases; Abbott Diabetes Care; National Institutes of Health; Eli Lilly and Company; Nipro; Insulet Corporation; Sanofi; Roche Diabetes Care","keywords":"Medicine; Hypoglycemia; Type 1 diabetes; Diabetes mellitus; Internal medicine; C-peptide; Incidence (geometry); Endocrinology; Type 2 diabetes; Gastroenterology; Meal","score_opus":0.02216269324971504,"score_gpt":0.3022768704062816,"score_spread":0.28011417715656656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126232165","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980915,0.0012587763,0.00010915883,0.000043994383,0.000013078007,0.000004257079,0.00018430015,0.0000064639285,0.00028853555],"genre_scores_gemma":[0.99931014,0.00018795782,0.000102762606,0.000029738367,0.000016427863,0.0000035116748,0.00024634454,0.0000025550173,0.00010053329],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99949205,0.00016121991,0.000059419093,0.00011857764,0.00007668853,0.00009199035],"domain_scores_gemma":[0.9964328,0.0005765488,0.0019671265,0.00021999814,0.00026824846,0.00053523417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013580874,0.0004125823,0.00045921002,0.0005631695,0.00030366308,0.0008749257,0.00035154098,0.0005191918,0.0015041399],"category_scores_gemma":[0.0026345165,0.00017670353,0.000588235,0.0007658165,0.00024450634,0.00034268573,0.000365799,0.00094876054,0.0001681043],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000725218,0.000060153307,0.9964573,0.000018434395,0.00011999317,0.000056258872,0.000023457489,0.000053492175,0.00022806258,0.00000748247,0.000057177745,0.0021931035],"study_design_scores_gemma":[0.000011431614,0.00024203763,0.99904364,0.000008780576,0.00007701838,0.00023696786,0.000040513132,0.00015257786,0.00006899151,0.000026100231,0.000088622,0.000003364859],"about_ca_topic_score_codex":0.0012585741,"about_ca_topic_score_gemma":0.0013644705,"teacher_disagreement_score":0.0015041399,"about_ca_system_score_codex":0.00015970133,"about_ca_system_score_gemma":0.00015806773,"threshold_uncertainty_score":0.0071823597},"labels":[],"label_agreement":null},{"id":"W3127215208","doi":"10.1172/jci140105","title":"RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Tech University; Hôpital Maisonneuve-Rosemont; Toronto General Hospital; University Health Network; University of Toronto; Princess Margaret Cancer Centre","funders":"Instituto de Salud Carlos III; Agència de Gestió d'Ajuts Universitaris i de Recerca; Canadian Institutes of Health Research; Ministero dello Sviluppo Economico; National Cancer Institute; University of Toronto; Cancer Research UK; Centres de Recerca de Catalunya; Government of Canada; Government of Ontario; Generalitat de Catalunya; Ministère du Développement Économique, de l’Innovation et de l’Exportation; European Regional Development Fund; European Commission; U.S. Department of Defense; Breast Cancer Research Foundation; Princess Margaret Cancer Foundation; Genome Canada; Fondation du cancer du sein du Québec; National Institutes of Health; Terry Fox Foundation; Ovarian Cancer Research Fund","keywords":"Genome instability; Biology; DNA damage; Carcinogenesis; DNA repair; Cancer research; Mitotic catastrophe; Genetics; Mutation; Mutagenesis; Cancer; DNA; Gene","score_opus":0.05132680537967718,"score_gpt":0.32501691343304573,"score_spread":0.2736901080533686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127215208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967037,0.0010130053,0.0011301342,0.00006727928,0.000014835034,0.00001799492,0.000189816,0.000158729,0.0007045276],"genre_scores_gemma":[0.995989,0.00039495,0.0013122838,0.000029986799,0.0000060557295,0.000024898507,0.00023889773,0.000035542555,0.001968289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988484,0.000019780475,0.000013328349,0.00002909908,0.000026871523,0.000026146285],"domain_scores_gemma":[0.999806,0.000020459145,0.00008262423,0.000013643476,0.0000140964075,0.0000632699],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013533418,0.00036783333,0.0002541886,0.0003255997,0.00013859938,0.00021842337,0.0002103565,0.00033146975,0.0010582276],"category_scores_gemma":[0.00013681268,0.00017113188,0.00018732173,0.00008306101,0.00021495474,0.00013447681,0.000166443,0.0003548033,0.0005278979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000905001,0.000018485405,0.0001552813,0.000012718883,0.0000019135002,0.000058804508,0.00000647771,0.000030771847,0.99906975,0.000027239426,0.000018769812,0.00050929666],"study_design_scores_gemma":[0.000023918707,0.00028413502,0.007251675,0.0000061809346,0.0000096276035,0.00069018675,0.000027551354,0.0012020844,0.9888536,0.00005242643,0.0015915822,0.0000069713037],"about_ca_topic_score_codex":0.00052503555,"about_ca_topic_score_gemma":0.00080795115,"teacher_disagreement_score":0.0010582276,"about_ca_system_score_codex":0.00029145952,"about_ca_system_score_gemma":0.00016559387,"threshold_uncertainty_score":0.0035400987},"labels":[],"label_agreement":null},{"id":"W3129175901","doi":"10.1172/jci142677","title":"Inhibition of relaxin autocrine signaling confers therapeutic vulnerability in ovarian cancer","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pregnancy-related medical research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Université de Montréal; University Health Network; University of Toronto; Princess Margaret Cancer Centre; Centre Hospitalier de l’Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Princess Margaret Cancer Foundation; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Autocrine signalling; Relaxin; Cancer research; Ovarian cancer; Cell growth; Biology; Signal transduction; Internal medicine; Cell culture; Cancer; Medicine; Endocrinology; Cell biology; Hormone","score_opus":0.17688710473950423,"score_gpt":0.46605408349202393,"score_spread":0.28916697875251973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129175901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99214184,0.004195811,0.0011404391,0.0002388018,0.000037813563,0.000035423836,0.00012642142,0.00006166719,0.0020217937],"genre_scores_gemma":[0.99615294,0.0021621394,0.00054465845,0.00005687497,0.000010511906,0.000021152271,0.00012131915,0.0000057891543,0.00092459493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999254,0.000016784948,0.000005296802,0.000010456819,0.000016993694,0.000025036183],"domain_scores_gemma":[0.9999466,0.000014201013,0.000014374798,0.0000073535884,0.0000040166274,0.00001338027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014061239,0.00014085784,0.00021995085,0.00013057678,0.0000905436,0.0002216128,0.00009321924,0.00013639548,0.0010793508],"category_scores_gemma":[0.00012718643,0.000062298095,0.00013512542,0.0000904429,0.00016330145,0.00013251233,0.00015618789,0.0005942559,0.00012113358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004309443,0.00014574258,0.000703665,0.00010401459,0.000011114904,0.0001345769,0.000036922313,0.00016184225,0.9862981,0.0002566098,0.00018862146,0.011527842],"study_design_scores_gemma":[0.00011543889,0.0046979603,0.01252916,0.00002110758,0.00007059888,0.0014301887,0.0001267743,0.0015058833,0.96564275,0.0002003403,0.013650828,0.0000089651185],"about_ca_topic_score_codex":0.00021106913,"about_ca_topic_score_gemma":0.0005441134,"teacher_disagreement_score":0.0010793508,"about_ca_system_score_codex":0.00013629589,"about_ca_system_score_gemma":0.00018808826,"threshold_uncertainty_score":0.0036107898},"labels":[],"label_agreement":null},{"id":"W3130957201","doi":"10.1172/jci126299","title":"Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute on Aging; Morsani College of Medicine; CurePSP; Florida Department of Health; BrightFocus Foundation; Alzheimer's Association","keywords":"Tauopathy; Polyamine; Neuroscience; Neuropathology; Tau protein; Ornithine decarboxylase antizyme; Biology; Cell biology; Hyperphosphorylation; Ornithine decarboxylase; Alzheimer's disease; Biochemistry; Neurodegeneration; Internal medicine; Medicine; Disease; Phosphorylation; Enzyme","score_opus":0.039259690142602624,"score_gpt":0.3446256645106422,"score_spread":0.3053659743680396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130957201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99115,0.0048748343,0.001959635,0.00015038942,0.000027694563,0.00001708564,0.00022320787,0.000055265635,0.0015419662],"genre_scores_gemma":[0.9944299,0.001418622,0.0012627657,0.00005316072,0.000017049084,0.000023138817,0.00035418465,0.000009607741,0.002431474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999118,0.000013074823,0.000008153365,0.000027050664,0.00002159736,0.000018421371],"domain_scores_gemma":[0.9999186,0.0000061289998,0.000033867553,0.0000064255437,0.000008466484,0.000026569996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108694716,0.00034853065,0.00019292893,0.0002476299,0.00014619411,0.0002697802,0.00013420102,0.00034668564,0.0007413003],"category_scores_gemma":[0.00007649552,0.00010580705,0.00011821687,0.00017683448,0.00025659535,0.00015857255,0.00015039464,0.0003755463,0.00020562806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002540815,0.000027175322,0.0011573641,0.000024676885,0.000007828179,0.00018383036,0.000011857919,0.000020844707,0.99683833,0.00007935104,0.00004275013,0.0013519363],"study_design_scores_gemma":[0.00003002339,0.00066314905,0.0790131,0.0000121083085,0.00004681863,0.002475056,0.00006663941,0.00088193256,0.9122456,0.00019933311,0.00435811,0.000008084779],"about_ca_topic_score_codex":0.0003648006,"about_ca_topic_score_gemma":0.00081072527,"teacher_disagreement_score":0.0007413003,"about_ca_system_score_codex":0.00024376615,"about_ca_system_score_gemma":0.00013215056,"threshold_uncertainty_score":0.0024799109},"labels":[],"label_agreement":null},{"id":"W3132473646","doi":"10.1172/jci145853","title":"Identification of SARS-CoV-2–specific immune alterations in acutely ill patients","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Public Health Agency of Canada; Government of Canada; Génome Québec; Public Health Agency","keywords":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Sars virus; Immune system; Coronavirus disease 2019 (COVID-19); Identification (biology); Medicine; Virology; 2019-20 coronavirus outbreak; Betacoronavirus; Immunology; Biology; Pathology; Infectious disease (medical specialty); Outbreak; Disease","score_opus":0.21838555335302123,"score_gpt":0.5037628925394119,"score_spread":0.28537733918639063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3132473646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9994192,0.00007677059,0.00010770594,0.000018807434,0.0000044227872,0.000015504886,0.00012050639,0.000003368606,0.0002337216],"genre_scores_gemma":[0.9993144,0.000059922124,0.00018065413,0.000055503904,0.000014881469,0.000013545261,0.00029207763,0.0000011350872,0.000067937835],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997936,0.000043610686,0.000030026285,0.000057251407,0.000026351787,0.000049227678],"domain_scores_gemma":[0.99973065,0.00004154061,0.00010198597,0.000019618989,0.000042337226,0.00006383056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020835994,0.00021740924,0.00035539406,0.00043079173,0.0002275596,0.00044145738,0.00013655737,0.00026931014,0.0010864395],"category_scores_gemma":[0.0006690753,0.00010041135,0.00016190001,0.0003162653,0.00017715953,0.00024879308,0.0003270934,0.0002908042,0.00018031885],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049174676,0.00007758915,0.97819227,0.000025696057,0.000022515458,0.0004914526,0.00017340003,0.000067724046,0.016510464,0.00004790091,0.00014422026,0.00375495],"study_design_scores_gemma":[0.000010041051,0.00034009005,0.9966168,0.000007705439,0.000012134897,0.0007210907,0.00023802667,0.00032442273,0.0014254603,0.000041132316,0.0002589241,0.000004303776],"about_ca_topic_score_codex":0.0005530416,"about_ca_topic_score_gemma":0.0006622053,"teacher_disagreement_score":0.0010864395,"about_ca_system_score_codex":0.00015287224,"about_ca_system_score_gemma":0.00019702244,"threshold_uncertainty_score":0.0036345124},"labels":[],"label_agreement":null},{"id":"W3133720646","doi":"10.1172/jci140752","title":"Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Hôpital Maisonneuve-Rosemont; McGill University; Jewish General Hospital","funders":"Terry Fox Research Institute; Canadian Institutes of Health Research; H2020 European Research Council; Réseau de cancérologie Rossy; Narodowe Centrum Badań i Rozwoju; McGill University","keywords":"Melanoma; Cancer research; Immunotherapy; CD8; EIF4E; Immune system; Immune checkpoint; Phenotype; Tumor microenvironment; Immunology; Biology; Medicine; Gene","score_opus":0.08551406362731641,"score_gpt":0.39733535910964496,"score_spread":0.31182129548232856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133720646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960963,0.00084472145,0.0011249334,0.00009322789,0.00004572035,0.000040430725,0.0002908268,0.00012766728,0.0013360884],"genre_scores_gemma":[0.99656457,0.00047585933,0.0009284303,0.000040994044,0.0000103136435,0.00005133025,0.00022051459,0.000014050399,0.0016939534],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980754,0.000032950717,0.000024018978,0.000029942574,0.000042627165,0.000062840816],"domain_scores_gemma":[0.99989235,0.000019181587,0.000029644887,0.000012759449,0.000005552745,0.000040370945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017224031,0.00050893036,0.00032817698,0.00029295834,0.00010284359,0.00024447814,0.00018538088,0.00027950417,0.00114585],"category_scores_gemma":[0.000095387615,0.00016845507,0.0002001989,0.00011168897,0.00020504776,0.00017816102,0.00019530655,0.00087298086,0.0002362509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003702115,0.00013382226,0.00013911612,0.000030553198,0.0000062759855,0.00001845264,0.000008523374,0.00015306714,0.9975376,0.00007626192,0.000046476587,0.0014797109],"study_design_scores_gemma":[0.000060680875,0.0015373233,0.0030096865,0.0000075454313,0.000021858636,0.00008962554,0.000016467884,0.0014326628,0.99194056,0.00004635331,0.0018323488,0.0000049625924],"about_ca_topic_score_codex":0.00029130172,"about_ca_topic_score_gemma":0.0006103555,"teacher_disagreement_score":0.00114585,"about_ca_system_score_codex":0.00023414163,"about_ca_system_score_gemma":0.0002055775,"threshold_uncertainty_score":0.0038332343},"labels":[],"label_agreement":null},{"id":"W3134525970","doi":"10.1172/jci142148","title":"Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Universitair Medisch Centrum Groningen; Ministerstvo Zdravotnictví Ceské Republiky; Ospedale Pediatrico Bambino Gesù; Ochsner Health; National Institutes of Health; Rijksuniversiteit Groningen; Hebrew University of Jerusalem; Amsterdam University Medical Centers; Univerzita Karlova v Praze; National Science Foundation; Hartstichting; University of Minnesota; Children's Hospital of Pittsburgh; Children's Heart Foundation; Leids Universitair Medisch Centrum; Universiteit Leiden","keywords":"Missense mutation; Phenotype; Cardiomyopathy; Exome sequencing; Heart disease; Biology; Internal medicine; Genetics; Medicine; Heart failure; Gene","score_opus":0.04665967952419232,"score_gpt":0.3509799135232749,"score_spread":0.3043202339990826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134525970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997259,0.0010638665,0.000750559,0.00008345436,0.0000071982813,0.0000087059425,0.00032080043,0.000018510029,0.00048779132],"genre_scores_gemma":[0.99881965,0.00029020067,0.0003139742,0.00003388164,0.0000072384055,0.000005381835,0.00022665861,0.000005109521,0.00029775564],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99986887,0.000014901516,0.000017676557,0.00004872167,0.000032273925,0.000017493026],"domain_scores_gemma":[0.9998944,0.00003126684,0.000038914146,0.00000790328,0.0000060222196,0.000021469128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001445249,0.00038146117,0.00020395563,0.00037259987,0.00017077994,0.0001738653,0.00016316338,0.00024239572,0.001884059],"category_scores_gemma":[0.00025443814,0.000118305965,0.00012681476,0.00027546578,0.00024864604,0.00008068962,0.00024045158,0.00027466068,0.0002231109],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011011818,0.00013829228,0.32047042,0.00015922033,0.00014110487,0.0115412725,0.00018737426,0.00028694313,0.63769317,0.00027960687,0.00057507487,0.027426306],"study_design_scores_gemma":[0.00006939322,0.0002935002,0.84087944,0.0000275487,0.00012980208,0.055121157,0.00019504507,0.0011383721,0.097354405,0.00020379294,0.004575596,0.000011961287],"about_ca_topic_score_codex":0.0004116532,"about_ca_topic_score_gemma":0.00071175484,"teacher_disagreement_score":0.001884059,"about_ca_system_score_codex":0.00015850422,"about_ca_system_score_gemma":0.00009635219,"threshold_uncertainty_score":0.0063028336},"labels":[],"label_agreement":null},{"id":"W3134797872","doi":"10.1172/jci146614","title":"HLA class I–associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":192,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Cedars-Sinai Medical Center; Foundation for the National Institutes of Health","keywords":"Superantigen; T-cell receptor; Biology; Immunology; Complementarity determining region; T cell; Immune system; Immunoglobulin light chain; Antibody","score_opus":0.04875685803445712,"score_gpt":0.34429199247103515,"score_spread":0.29553513443657803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134797872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991548,0.00018326896,0.00019344343,0.00001948202,0.000004044593,0.0000073860065,0.000093251605,0.000008743872,0.00033551647],"genre_scores_gemma":[0.9993407,0.0001391791,0.00024970353,0.00002537721,0.000008242696,0.0000050708504,0.00014158727,0.0000043897157,0.000085644744],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99975425,0.000038058588,0.000023284081,0.000074326876,0.000045604847,0.00006442167],"domain_scores_gemma":[0.9997526,0.000046477195,0.00009700353,0.000012519909,0.000022347309,0.000068944406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016697664,0.00040039018,0.00024172387,0.0004813427,0.00023822441,0.00031247546,0.00013122185,0.00033981376,0.0013268358],"category_scores_gemma":[0.0004889374,0.00018257053,0.00027828396,0.00039734054,0.0002807873,0.00017622515,0.0002719702,0.00044221952,0.00019148589],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060121354,0.00007052325,0.86308414,0.00014137516,0.000059518017,0.0126176225,0.00056066155,0.0003640483,0.109562226,0.00018348669,0.00040211977,0.012353231],"study_design_scores_gemma":[0.000022120672,0.00034732616,0.9528191,0.000022079974,0.000062086074,0.03513842,0.00038433023,0.00052817975,0.0087134745,0.00007881163,0.0018742911,0.000009680908],"about_ca_topic_score_codex":0.00095361896,"about_ca_topic_score_gemma":0.00087425107,"teacher_disagreement_score":0.0013268358,"about_ca_system_score_codex":0.00023314473,"about_ca_system_score_gemma":0.0001855234,"threshold_uncertainty_score":0.0044386983},"labels":[],"label_agreement":null},{"id":"W3135211510","doi":"10.1172/jci94229","title":"Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"Vanderbilt University; National Eye Institute; National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Autophagy; TFEB; Cell biology; Basic helix-loop-helix leucine zipper transcription factors; Lysosome; Foam cell; Transcription factor; Biology; Inflammation; Macrophage; Downregulation and upregulation; Apoptosis; Chemistry; Immunology; Biochemistry; Gene; DNA-binding protein","score_opus":0.10494296268656822,"score_gpt":0.37810959072109723,"score_spread":0.273166628034529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135211510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885048,0.0066016368,0.0029664517,0.00021438376,0.000047341116,0.000024914825,0.00031719025,0.00013526701,0.0011879847],"genre_scores_gemma":[0.9933357,0.0016704889,0.0016643928,0.00007081265,0.000017531574,0.00004724361,0.00053979654,0.00002631949,0.0026276968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997886,0.00005220674,0.000024912346,0.000043466098,0.000041911346,0.000048940765],"domain_scores_gemma":[0.99990034,0.000006611152,0.00003413132,0.000009447721,0.000018866496,0.00003066315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020384305,0.0003652021,0.00044273093,0.0003857121,0.00026272255,0.00029525338,0.00015913192,0.00031696106,0.0009675628],"category_scores_gemma":[0.00012709259,0.00022174705,0.00033548492,0.00022536605,0.00024759545,0.00024598412,0.00028926565,0.00047367907,0.0004265749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028716293,0.000014516841,0.00016798584,0.000036928523,0.0000041513936,0.000046509344,0.00001533629,0.000029478819,0.9986034,0.00008253375,0.000030675696,0.0006812565],"study_design_scores_gemma":[0.000083650564,0.00037029467,0.021722488,0.000020311973,0.00006645586,0.0007893158,0.00009416412,0.0017066636,0.97003067,0.0003143594,0.0047829403,0.000018763338],"about_ca_topic_score_codex":0.00038750292,"about_ca_topic_score_gemma":0.00037705156,"teacher_disagreement_score":0.0009675628,"about_ca_system_score_codex":0.00033324127,"about_ca_system_score_gemma":0.00020673468,"threshold_uncertainty_score":0.0032368302},"labels":[],"label_agreement":null},{"id":"W3135521810","doi":"10.1172/jci146821","title":"YAP/TFEB pathway promotes autophagic cell death and hypertrophic cardiomyopathy in lysosomal storage diseases","year":2021,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"TFEB; Autophagy; Lysosome; Cell biology; Basic helix-loop-helix leucine zipper transcription factors; Transcription factor; Biology; Programmed cell death; Biochemistry; Enzyme; Gene; Apoptosis","score_opus":0.05679981380302977,"score_gpt":0.3237844179697605,"score_spread":0.2669846041667307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135521810","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13713354,0.019182272,0.0023240182,0.76127106,0.034317646,0.0001942083,0.00027134918,0.0006368404,0.04466912],"genre_scores_gemma":[0.5277755,0.016615707,0.0024947731,0.3045956,0.10289064,0.00023846135,0.00026494428,0.00009201986,0.045032326],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9997367,0.00008031116,0.000030626747,0.000034621742,0.00006727139,0.000050477393],"domain_scores_gemma":[0.9991247,0.00039267185,0.00007719435,0.000056782,0.00018282283,0.00016589093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000532501,0.00042685276,0.0006226746,0.0003796923,0.0010553579,0.0007186332,0.00035855352,0.00600252,0.0019155408],"category_scores_gemma":[0.0021898397,0.00022946775,0.00048820628,0.0002378157,0.00075409125,0.00062074023,0.0003387906,0.0041266717,0.0012820037],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017766104,0.00044848432,0.019082218,0.00054708926,0.00009781865,0.33261627,0.0005468448,0.0005396598,0.018420873,0.008498057,0.5498676,0.067558564],"study_design_scores_gemma":[0.0015159994,0.0014190385,0.044415515,0.0005539796,0.00022415031,0.3848876,0.0009013844,0.007871576,0.017486569,0.017538328,0.5229907,0.00019506506],"about_ca_topic_score_codex":0.0005766898,"about_ca_topic_score_gemma":0.0009723511,"teacher_disagreement_score":0.00600252,"about_ca_system_score_codex":0.0009699783,"about_ca_system_score_gemma":0.00046168402,"threshold_uncertainty_score":0.007037699},"labels":[],"label_agreement":null},{"id":"W3139636803","doi":"10.1172/jci140709","title":"UDP-glucose and P2Y14 receptor amplify allergen-induced airway eosinophilia","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Uniwersytet Jagielloński Collegium Medicum","keywords":"Eosinophilia; Eosinophil; Immunology; Asthma; Ovalbumin; Medicine; Airway; Allergen; Sensitization; Pulmonary Eosinophilia; Allergy; Antigen; Anesthesia","score_opus":0.08356922333767017,"score_gpt":0.38056367557806503,"score_spread":0.2969944522403949,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139636803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949185,0.0021984896,0.0012416694,0.0002103167,0.000044406606,0.000056313707,0.00010241145,0.000054995195,0.0011728539],"genre_scores_gemma":[0.99526876,0.0011277682,0.0012507752,0.00009696085,0.000031184234,0.000052533167,0.0001435612,0.00001171561,0.0020167283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999742,0.0000663028,0.000015594209,0.000030175437,0.000053447293,0.00009257914],"domain_scores_gemma":[0.9998976,0.000013951593,0.00003158333,0.000008757335,0.000007580049,0.00004050726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018367525,0.00041108558,0.00039687377,0.00023090905,0.00010424931,0.0003807485,0.00023634349,0.0005514906,0.0012789578],"category_scores_gemma":[0.00017334089,0.00017746183,0.00028772565,0.00008284545,0.00035204034,0.00035118373,0.00033567657,0.0011236228,0.00029739455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069575023,0.00011391195,0.00033941178,0.000042957436,0.000006163738,0.00021987506,0.000011877449,0.00006380229,0.9958478,0.0001312129,0.00007497914,0.0024520734],"study_design_scores_gemma":[0.00025709707,0.0038925784,0.020070422,0.000017897957,0.000048488364,0.0013707929,0.000112768066,0.002091065,0.96736264,0.00020224808,0.004558202,0.000015952388],"about_ca_topic_score_codex":0.00024212408,"about_ca_topic_score_gemma":0.00040071478,"teacher_disagreement_score":0.0012789578,"about_ca_system_score_codex":0.00019736693,"about_ca_system_score_gemma":0.00017467121,"threshold_uncertainty_score":0.0042785406},"labels":[],"label_agreement":null},{"id":"W3154437481","doi":"10.1172/jci143990","title":"The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Human Genome Research Institute; National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Finasteride; Opioid; Medicine; Dehydroepiandrosterone sulfate; Opioid use disorder; Pharmacology; Hyperalgesia; Internal medicine; Endocrinology; Nociception; Androgen; Receptor","score_opus":0.09467827892443573,"score_gpt":0.37458366257219483,"score_spread":0.2799053836477591,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3154437481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99165595,0.0024135874,0.0013524017,0.00042284603,0.000079751866,0.00011340433,0.00091934064,0.00023142954,0.002811313],"genre_scores_gemma":[0.9867318,0.00342468,0.0016353518,0.00018382011,0.00001801457,0.000120624405,0.0008193355,0.000025529307,0.0070408895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998411,0.000023760218,0.000012103065,0.000018268567,0.000050582275,0.00005412127],"domain_scores_gemma":[0.99986017,0.000013336132,0.00003996498,0.000010842468,0.000020955766,0.00005466823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001613866,0.00050247443,0.0004487761,0.0006801945,0.0002795143,0.00024819508,0.00023804368,0.00034571748,0.0023587022],"category_scores_gemma":[0.00018991777,0.00022425682,0.00033925928,0.00027026908,0.0003851508,0.0002686234,0.00016772085,0.0009389369,0.00027891962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012840373,0.00037551037,0.0005840636,0.000101296806,0.0000351591,0.000068493406,0.000038525373,0.000095548196,0.9914771,0.00008265665,0.0002577797,0.0055998815],"study_design_scores_gemma":[0.00023318171,0.009380493,0.021647487,0.000034539626,0.00010348284,0.00021364231,0.00019799767,0.0007964835,0.96416074,0.000096830154,0.0031105443,0.000024582117],"about_ca_topic_score_codex":0.0080928495,"about_ca_topic_score_gemma":0.036738962,"teacher_disagreement_score":0.0080928495,"about_ca_system_score_codex":0.00064042286,"about_ca_system_score_gemma":0.0006001539,"threshold_uncertainty_score":0.016091466},"labels":[],"label_agreement":null},{"id":"W3157396950","doi":"10.1172/jci143078","title":"C2orf69 mutations disrupt mitochondrial function and cause a multisystem human disorder with recurring autoinflammation","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; BC Children's Hospital","funders":"RWTH Aachen University; Deutsche Forschungsgemeinschaft","keywords":"Function (biology); Medicine; Mutation; Genetics; Biology; Gene","score_opus":0.04262870252707986,"score_gpt":0.341270778211756,"score_spread":0.29864207568467616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3157396950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972127,0.0005306684,0.0010069112,0.00009826626,0.000018571798,0.000027744909,0.00031629388,0.00006840545,0.00072049594],"genre_scores_gemma":[0.9986156,0.00014167209,0.0007147077,0.00004494352,0.000017105376,0.000006958636,0.00020196669,0.0000100725565,0.00024694222],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99981755,0.00002333266,0.000022645521,0.000065661356,0.00003840732,0.000032424417],"domain_scores_gemma":[0.9998017,0.000039425635,0.00007884312,0.000016686958,0.000015317546,0.000047944108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013958801,0.0013184858,0.00035215582,0.00058295834,0.0005221405,0.00021857713,0.0001850582,0.00083455694,0.0012870708],"category_scores_gemma":[0.00039296807,0.00011086767,0.00024061787,0.00040866382,0.0004938584,0.00015386434,0.00036906466,0.00031570316,0.000189862],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012304178,0.00019696803,0.057123695,0.00020872793,0.00017796956,0.14763032,0.0003749382,0.0007836577,0.77340055,0.0007552015,0.001275011,0.016842518],"study_design_scores_gemma":[0.00015395127,0.0009165463,0.3977452,0.00009609404,0.00024171983,0.42699513,0.00032272632,0.0028774778,0.16290723,0.00092397013,0.006742523,0.000077495984],"about_ca_topic_score_codex":0.0007982327,"about_ca_topic_score_gemma":0.0015278886,"teacher_disagreement_score":0.0013184858,"about_ca_system_score_codex":0.00029420442,"about_ca_system_score_gemma":0.00020034329,"threshold_uncertainty_score":0.0043056607},"labels":[],"label_agreement":null},{"id":"W3158351699","doi":"10.1172/jci136459","title":"Frataxin deficiency promotes endothelial senescence in pulmonary hypertension","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto","funders":"National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; National Institute on Aging; National Cancer Institute; National Institutes of Health; Agence Nationale de la Recherche; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; American Heart Association","keywords":"Senescence; Pulmonary hypertension; Medicine; Biology; Internal medicine","score_opus":0.06294846259037065,"score_gpt":0.32839955593016923,"score_spread":0.26545109333979855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158351699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99811625,0.00073927257,0.00047973212,0.00008931454,0.000014820935,0.0000076167175,0.000030444535,0.000030810777,0.0004916503],"genre_scores_gemma":[0.9988111,0.00035219305,0.00016757479,0.000024671994,0.000009723502,0.000006111956,0.000036754853,0.0000031585844,0.0005886469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999281,0.000023574084,0.0000075305848,0.00001231939,0.000011632573,0.000016776337],"domain_scores_gemma":[0.9998417,0.000028024071,0.000052174222,0.000014094653,0.000012045073,0.000051930987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019711792,0.0001240031,0.00015413304,0.00019551505,0.00014066683,0.00019246135,0.00007678728,0.00023727417,0.0010137559],"category_scores_gemma":[0.00018226822,0.0001011363,0.0001324633,0.000086619504,0.00020778441,0.00014437958,0.00015574635,0.000343729,0.00016757203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008048886,0.00010467724,0.0029772504,0.000037467576,0.000009955263,0.00078954984,0.000043259282,0.000034764817,0.9923062,0.00021031212,0.000114209026,0.0025675688],"study_design_scores_gemma":[0.00026456776,0.0035476186,0.24285603,0.000047307305,0.00008870044,0.013525287,0.00029637435,0.002540048,0.7289089,0.0007856502,0.0071206745,0.000018781653],"about_ca_topic_score_codex":0.00022027784,"about_ca_topic_score_gemma":0.00031724764,"teacher_disagreement_score":0.0010137559,"about_ca_system_score_codex":0.00016099498,"about_ca_system_score_gemma":0.00011564267,"threshold_uncertainty_score":0.0033913255},"labels":[],"label_agreement":null},{"id":"W3160112606","doi":"10.1172/jci147878","title":"Tumor subtype defines distinct pathways of molecular and clinical progression in primary prostate cancer","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome British Columbia","funders":"Memorial Sloan-Kettering Cancer Center; Associazione Italiana per la Ricerca sul Cancro; Urology Care Foundation; College of Veterinary Medicine, Cornell University; MetLife Foundation; Damon Runyon Cancer Research Foundation; National Cancer Institute; Prostate Cancer Foundation; Weill Cornell Medical College; U.S. Department of Defense","keywords":"Prostate cancer; Cancer; Disease; Natural history; Biology; Prostate; Pathology; Medicine; Computational biology; Cancer research; Internal medicine; Genetics","score_opus":0.09844316615881343,"score_gpt":0.43650898699870433,"score_spread":0.3380658208398909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160112606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971205,0.000431537,0.0013528059,0.00004334076,0.000002843423,0.000024913343,0.00043224872,0.000031485128,0.00056028005],"genre_scores_gemma":[0.99831474,0.00015821206,0.00054469774,0.000014319676,0.0000050695253,0.000012757166,0.0007372256,0.0000075734356,0.00020531726],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99978405,0.0000434236,0.000014179315,0.000051648938,0.000066512875,0.000040149807],"domain_scores_gemma":[0.99938846,0.00013215069,0.00024570356,0.00007046336,0.00007839292,0.00008490317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005102713,0.00022287788,0.0002516096,0.00055619114,0.00019927659,0.00051058806,0.0002215754,0.00019125562,0.0007555086],"category_scores_gemma":[0.00090042094,0.00010160241,0.0002593283,0.0003713495,0.00021762843,0.00021026567,0.00024066443,0.00034993349,0.00020518134],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006351673,0.000077702774,0.9334442,0.00006355042,0.0000644701,0.00015718307,0.00016119164,0.0015416478,0.04809248,0.00061270694,0.00025233193,0.014897358],"study_design_scores_gemma":[0.00000896161,0.00024205637,0.9875788,0.000008967645,0.000041774936,0.0006655884,0.0001826653,0.0035797094,0.0056095757,0.0012492364,0.00082274753,0.000009787737],"about_ca_topic_score_codex":0.0015523916,"about_ca_topic_score_gemma":0.0030095107,"teacher_disagreement_score":0.0015523916,"about_ca_system_score_codex":0.00035124633,"about_ca_system_score_gemma":0.00044028065,"threshold_uncertainty_score":0.0030867457},"labels":[],"label_agreement":null},{"id":"W3161754417","doi":"10.1172/jci146077","title":"Multiple-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Blood groups and transfusion","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Hemolysis; Genome-wide association study; Biology; Genetics; Genome; Genetic association; Computational biology; Blood preservation; Association (psychology); Single-nucleotide polymorphism; Gene; Genotype; Immunology; Physiology; Psychology","score_opus":0.08684496741831424,"score_gpt":0.3407456264930424,"score_spread":0.25390065907472814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161754417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977806,0.0006262171,0.00049658096,0.00013601712,0.000014296682,0.000008112411,0.0006117359,0.000018526971,0.00030794003],"genre_scores_gemma":[0.99868256,0.00016357681,0.0004526231,0.000048136008,0.000012553711,0.000009032998,0.0003896216,0.000007051785,0.00023493727],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99925524,0.00019099284,0.000071078706,0.0003135843,0.000075557175,0.0000934802],"domain_scores_gemma":[0.99901843,0.00027762365,0.00033969225,0.00014150194,0.00007674559,0.0001461327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009777048,0.000557112,0.00047153136,0.00064715085,0.00060336484,0.00067722844,0.00053133717,0.0007317073,0.0025382615],"category_scores_gemma":[0.0014294187,0.00029401516,0.0008063798,0.0013791688,0.00040378474,0.0002148359,0.0005318515,0.00084623176,0.00014069595],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010993519,0.00007579389,0.9848408,0.000047713198,0.0017887879,0.00048613746,0.00016455834,0.00020493958,0.00631187,0.0001659531,0.0005040934,0.004310005],"study_design_scores_gemma":[0.000042063286,0.00007826834,0.9980381,0.000007725456,0.00037824086,0.00034480268,0.000062381805,0.0003521422,0.0003046244,0.00011566307,0.00026985828,0.000006160105],"about_ca_topic_score_codex":0.0051950086,"about_ca_topic_score_gemma":0.0063908966,"teacher_disagreement_score":0.0051950086,"about_ca_system_score_codex":0.0001817507,"about_ca_system_score_gemma":0.00025000886,"threshold_uncertainty_score":0.010329545},"labels":[],"label_agreement":null},{"id":"W3162082239","doi":"10.1172/jci141801","title":"Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; University of Pennsylvania; U.S. Department of Veterans Affairs","keywords":"Biology; Genome-wide association study; Transcriptome; Kidney disease; Chromatin; Genetics; Gene; Gene expression; Genotype; Single-nucleotide polymorphism; Endocrinology","score_opus":0.03907101928606648,"score_gpt":0.35228091504905734,"score_spread":0.31320989576299085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3162082239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9695379,0.0038612618,0.017938271,0.0004045701,0.000077592085,0.000027283142,0.005893923,0.0003863816,0.0018727687],"genre_scores_gemma":[0.9909943,0.000860007,0.0048597935,0.00017121814,0.00002879895,0.000018804822,0.0022046329,0.00005483138,0.00080764416],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999508,0.00008457671,0.000030793923,0.00023388799,0.00009813906,0.00004455796],"domain_scores_gemma":[0.9994686,0.00020544346,0.00015295083,0.00006135822,0.000046038353,0.00006563782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006746141,0.0003257742,0.00041558428,0.00078264,0.00032489645,0.00042032113,0.00018532804,0.00030507686,0.0029890593],"category_scores_gemma":[0.0008300083,0.00014977084,0.0005559487,0.0009001974,0.00022754898,0.000114600036,0.00039145676,0.00054352486,0.00018907651],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018527842,0.00010615204,0.43526277,0.00068145397,0.0021986854,0.0015979388,0.00031850423,0.0020735105,0.48018312,0.0019108916,0.0025046924,0.07130955],"study_design_scores_gemma":[0.00008779799,0.00017495552,0.93416476,0.000055318185,0.0015068689,0.0028285633,0.00009673265,0.006627593,0.0438361,0.0015388592,0.009043917,0.000038424932],"about_ca_topic_score_codex":0.0017497187,"about_ca_topic_score_gemma":0.0033456518,"teacher_disagreement_score":0.0029890593,"about_ca_system_score_codex":0.00021759546,"about_ca_system_score_gemma":0.00030519438,"threshold_uncertainty_score":0.009999394},"labels":[],"label_agreement":null},{"id":"W3163745522","doi":"10.1172/jci149948","title":"Innovations in MD-only physician-scientist training: experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Health and Medical Research Impacts","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institutes of Health","keywords":"Medicine; Alternative medicine; Medical education; Family medicine; Pathology","score_opus":0.4517209177133293,"score_gpt":0.5085931876884476,"score_spread":0.05687226997511835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163745522","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":"incentives","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":"incentives","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43620554,0.011159088,0.0042690015,0.45158935,0.012279965,0.0013924389,0.00066760083,0.00032789822,0.08210912],"genre_scores_gemma":[0.88889927,0.007897555,0.0073225163,0.054967564,0.0036524523,0.00054351386,0.00069495,0.00019602377,0.035826214],"study_design_codex":"design_other","study_design_gemma":"qualitative","domain_scores_codex":[0.96597934,0.014281536,0.00089590973,0.0011404143,0.006700561,0.011002273],"domain_scores_gemma":[0.8835103,0.016393539,0.00356921,0.0023091135,0.008547282,0.08567058],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.056714587,0.00065917656,0.0006332838,0.001507211,0.007532872,0.010839779,0.0030926454,0.005906299,0.012183465],"category_scores_gemma":[0.046059456,0.0004210353,0.0010093951,0.002117086,0.0052781613,0.003129174,0.015434424,0.010822394,0.001302323],"study_design_candidate":"qualitative","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030374886,0.0153492885,0.06327217,0.0010862235,0.00026186198,0.0038920643,0.047073998,0.0013431669,0.0050301603,0.07564653,0.29876712,0.4852399],"study_design_scores_gemma":[0.0030867623,0.0085159475,0.18840308,0.0010131052,0.00017780335,0.0011351071,0.0584902,0.0013112841,0.002301246,0.0131249465,0.7221666,0.00027383317],"about_ca_topic_score_codex":0.017269794,"about_ca_topic_score_gemma":0.051449675,"teacher_disagreement_score":0.9432854,"about_ca_system_score_codex":0.0111743,"about_ca_system_score_gemma":0.0680834,"threshold_uncertainty_score":0.29993898},"labels":[],"label_agreement":null},{"id":"W3163808478","doi":"10.1172/jci150646","title":"A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":172,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Skoll Foundation","keywords":"Medicine; Randomized controlled trial; Convalescent plasma; Confidence interval; Odds ratio; Internal medicine; Randomization; Population; Coronavirus disease 2019 (COVID-19); Disease","score_opus":0.1608629859128422,"score_gpt":0.4484897559255046,"score_spread":0.2876267700126624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163808478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9355608,0.009573802,0.0027722458,0.0019604883,0.0048232675,0.039806318,0.0016970851,0.00037738564,0.0034285593],"genre_scores_gemma":[0.93013144,0.0034094343,0.0060986294,0.0025908842,0.0013825399,0.05153745,0.0009930582,0.000036241858,0.0038202358],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99724126,0.0015828063,0.00024369656,0.00049751304,0.0001613559,0.00027336122],"domain_scores_gemma":[0.99732447,0.00087751105,0.00067917036,0.00023751131,0.00026834747,0.00061287486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00407607,0.0022035984,0.0049326085,0.0005964331,0.00078806345,0.0012716618,0.0011575922,0.003091737,0.009376083],"category_scores_gemma":[0.005762918,0.00085362874,0.002125497,0.0004888204,0.001834396,0.001528064,0.00067830813,0.0027785813,0.0009435343],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.9912793,0.003770769,0.00014224289,0.00053508935,0.00040201287,0.000012363798,0.00002343211,0.000054685086,0.00031700064,0.00006879879,0.00027796737,0.00311628],"study_design_scores_gemma":[0.98679954,0.01260825,0.00016991553,0.000019147206,0.00010441999,0.00000371182,0.0000060780303,0.00008041718,0.000034262477,0.000051716495,0.00011892361,0.0000036168428],"about_ca_topic_score_codex":0.0011308898,"about_ca_topic_score_gemma":0.0019154898,"teacher_disagreement_score":0.009376083,"about_ca_system_score_codex":0.0008635782,"about_ca_system_score_gemma":0.0023456886,"threshold_uncertainty_score":0.03136611},"labels":[],"label_agreement":null},{"id":"W3165277981","doi":"10.1172/jci147834","title":"Rare loss-of-function variants in type I IFN immunity genes are not associated with severe COVID-19","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; McGill Genome Centre; McGill University; Jewish General Hospital","funders":"National Center for Advancing Translational Sciences; National Institute on Aging","keywords":"Biology; Gene; Exome sequencing; Genetics; Population; Candidate gene; Loss function; Coronavirus disease 2019 (COVID-19); Exome; Mutation; Disease; Medicine; Phenotype; Internal medicine","score_opus":0.10748775227812225,"score_gpt":0.36260536439297014,"score_spread":0.2551176121148479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3165277981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979482,0.0002345479,0.00042103103,0.000055808916,0.000008147271,0.000009268122,0.0006731311,0.000010358226,0.000639579],"genre_scores_gemma":[0.9989502,0.00007631392,0.00021877748,0.000043823522,0.000010508382,0.0000040127893,0.0005712099,0.000007813978,0.00011746431],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99927074,0.00010078343,0.000099466684,0.00026425498,0.00013144097,0.0001333789],"domain_scores_gemma":[0.9973152,0.0007172401,0.0011975139,0.00025050892,0.00019007253,0.0003293185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063032546,0.00048028943,0.0004950034,0.000910321,0.0005881817,0.00068696315,0.0003866188,0.0005242367,0.0034230019],"category_scores_gemma":[0.0044853645,0.00023184707,0.0005496864,0.0008903612,0.0006176611,0.0003384405,0.00063945714,0.0006060263,0.00024649734],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005071989,0.000015200745,0.9880413,0.00003495353,0.00013761815,0.0013644254,0.00008508654,0.00007808091,0.00689656,0.000082876315,0.00017101836,0.002585739],"study_design_scores_gemma":[0.000022964028,0.000120640034,0.9919938,0.000025012634,0.00009180672,0.0051285364,0.00013254835,0.0002679706,0.0014231873,0.00018012844,0.0006042118,0.0000093439],"about_ca_topic_score_codex":0.0016850862,"about_ca_topic_score_gemma":0.002256652,"teacher_disagreement_score":0.0034230019,"about_ca_system_score_codex":0.00020310932,"about_ca_system_score_gemma":0.0001962631,"threshold_uncertainty_score":0.011451066},"labels":[],"label_agreement":null},{"id":"W3166796049","doi":"10.1172/jci146870","title":"Dysregulation of mannose-6-phosphate–dependent cholesterol homeostasis in acinar cells mediates pancreatitis","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; U.S. Department of Veterans Affairs","keywords":"Homeostasis; Pancreatitis; Endocrinology; Internal medicine; Mannose; Chemistry; Cholesterol; Phosphate; Medicine; Biology; Biochemistry","score_opus":0.05178799354188177,"score_gpt":0.35448938409210284,"score_spread":0.30270139055022105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166796049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864835,0.007406366,0.0039229193,0.0003598243,0.0000389225,0.00004114989,0.00014948918,0.00011389307,0.0014838104],"genre_scores_gemma":[0.9942462,0.0034193397,0.0014852707,0.00006090155,0.00001578974,0.000022746659,0.00011162426,0.000009321491,0.00062891695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998678,0.000033407152,0.000016326125,0.00002179169,0.00003454468,0.000026059734],"domain_scores_gemma":[0.9998872,0.000013692072,0.00003611504,0.000014987045,0.000012112712,0.0000357727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018892945,0.0002947727,0.0003469384,0.0002421527,0.00024986922,0.000483134,0.00014896215,0.0003146956,0.0007634942],"category_scores_gemma":[0.00018484218,0.00010209967,0.00019200219,0.00018379386,0.00038415618,0.00029591678,0.00040220754,0.00083096186,0.00028452283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032688116,0.00003265392,0.0010315789,0.00006895347,0.000009068341,0.0002785506,0.000017718141,0.000053196796,0.9943573,0.0001962317,0.00005365924,0.00357411],"study_design_scores_gemma":[0.00004321681,0.00038140864,0.017902136,0.00002402782,0.000035959023,0.002521039,0.00008005647,0.0010157491,0.973334,0.0004519021,0.004200355,0.000010184193],"about_ca_topic_score_codex":0.0002241311,"about_ca_topic_score_gemma":0.00026127076,"teacher_disagreement_score":0.0007634942,"about_ca_system_score_codex":0.00032323552,"about_ca_system_score_gemma":0.00027223144,"threshold_uncertainty_score":0.0025541782},"labels":[],"label_agreement":null},{"id":"W3172983054","doi":"10.1172/jci148272","title":"Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta; University of Toronto; BC Children's Hospital","funders":"Canadian Institutes of Health Research; Radboud Universiteit; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Stichting Stofwisselkracht","keywords":"Metabolomics; Pyridoxine; Epilepsy; Chemistry; Infrared spectroscopy; Spectroscopy; Medicine; Computational biology; Biochemistry; Biology; Chromatography; Psychiatry; Physics; Organic chemistry","score_opus":0.04049993282197334,"score_gpt":0.3593608151586908,"score_spread":0.31886088233671744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172983054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88552535,0.02810691,0.07364032,0.0013941327,0.00055830844,0.00025771544,0.0033770977,0.001301379,0.005838826],"genre_scores_gemma":[0.9216569,0.008074,0.06005215,0.0015721112,0.0002369916,0.00021643727,0.0015312744,0.00015294939,0.0065071965],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999403,0.00008640948,0.000026918577,0.00021499331,0.00019544436,0.0000733145],"domain_scores_gemma":[0.99966085,0.000076949706,0.00010944543,0.000031414944,0.000082371196,0.000039039114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006603191,0.0011375821,0.0006166453,0.0013850967,0.00022850778,0.00072630995,0.00050172134,0.0012074693,0.0011478547],"category_scores_gemma":[0.000756745,0.00032679917,0.00059729436,0.00063750223,0.00037044645,0.00056445465,0.0008404216,0.00077494263,0.00045887486],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006580113,0.000106439504,0.011381055,0.00039328705,0.00023145303,0.00041729162,0.00007090637,0.00050253083,0.95191014,0.0002972315,0.00069057936,0.033341],"study_design_scores_gemma":[0.0000672541,0.0010080301,0.04658269,0.00009212019,0.00040572064,0.0032606446,0.00017158416,0.010310201,0.9277333,0.0015066451,0.008761982,0.00009972458],"about_ca_topic_score_codex":0.00042829418,"about_ca_topic_score_gemma":0.00082000205,"teacher_disagreement_score":0.0013850967,"about_ca_system_score_codex":0.00030763895,"about_ca_system_score_gemma":0.00025643077,"threshold_uncertainty_score":0.0038399696},"labels":[],"label_agreement":null},{"id":"W3173280716","doi":"10.1172/jci138022","title":"Serine hydroxymethyltransferase 2 expression promotes tumorigenesis in rhabdomyosarcoma with 12q13-q14 amplification","year":2021,"lang":"zh","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"Medical School, University of Michigan; National Institutes of Health; George Washington University; National Cancer Institute; Princeton University","keywords":"Amplicon; Biology; Carcinogenesis; Cancer research; Rhabdomyosarcoma; Serine hydroxymethyltransferase; Molecular biology; Gene; Genetics; Serine; Polymerase chain reaction; Pathology; Sarcoma; Medicine","score_opus":0.03517303986054794,"score_gpt":0.33110741566287344,"score_spread":0.2959343758023255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173280716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993788,0.00020028281,0.00018951495,0.000012555324,0.0000017122047,0.000003816296,0.000031164473,0.000014605575,0.00016758259],"genre_scores_gemma":[0.99926466,0.00012703757,0.00019899468,0.000007735821,0.0000019748825,0.000005196864,0.00008865429,0.0000026852895,0.00030290472],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999002,0.000016549415,0.000010171393,0.00001547836,0.000029956691,0.000027661532],"domain_scores_gemma":[0.9998853,0.000027183078,0.00003887796,0.000009383968,0.000011807672,0.000027383972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013914733,0.00019932618,0.00019836909,0.0003328447,0.0001052595,0.00018077211,0.00007316729,0.0001599165,0.0006804691],"category_scores_gemma":[0.00013997775,0.00015992353,0.00016883586,0.00015218373,0.00018519502,0.000098168835,0.00016792103,0.00024909782,0.00015215194],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018884098,0.000020655709,0.00504367,0.000015253793,0.000008096448,0.00020180175,0.000024729854,0.00006553106,0.9937158,0.000020769665,0.000018775623,0.0006761401],"study_design_scores_gemma":[0.00003791475,0.0012063127,0.29861894,0.000007530457,0.00007284246,0.0024628744,0.00018286573,0.002734414,0.6933921,0.00007936922,0.0011959147,0.000008881005],"about_ca_topic_score_codex":0.000666967,"about_ca_topic_score_gemma":0.0009882447,"teacher_disagreement_score":0.0006804691,"about_ca_system_score_codex":0.00014093361,"about_ca_system_score_gemma":0.00011597352,"threshold_uncertainty_score":0.0022764206},"labels":[],"label_agreement":null},{"id":"W3174972846","doi":"10.1172/jci144201","title":"Passive transfer of fibromyalgia symptoms from patients to mice","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":266,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Seventh Framework Programme; Horizon 2020 Framework Programme; Medical Research Council; Versus Arthritis; Karolinska Institutet; Stiftelsen Konung Gustaf V:s 80-årsfond; Vetenskapsrådet; Home Office; Pain Relief Foundation; European Commission; Stockholms Läns Landsting; Knut och Alice Wallenbergs Stiftelse; Menzies Centre for Australian Studies, King's College London, University of London; Eli Lilly and Company; King's College London; National Institute for Health and Care Research","keywords":"Medicine; Fibromyalgia; Nociception; Stimulation; Spinal cord; Pathophysiology; Immunology; Anesthesia; Internal medicine; Endocrinology; Receptor","score_opus":0.05160136888946774,"score_gpt":0.36433184579196715,"score_spread":0.3127304769024994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174972846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9752882,0.002997035,0.006812099,0.0013520055,0.0007416442,0.0017097358,0.0028580786,0.00071949,0.0075217187],"genre_scores_gemma":[0.967574,0.0026344033,0.008988422,0.0014808213,0.0004253461,0.0016078664,0.0053952215,0.00013467809,0.011759347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870515,0.00026332753,0.00018058291,0.00041316997,0.00015407352,0.00028368254],"domain_scores_gemma":[0.99935716,0.00018768007,0.00013661271,0.00012487292,0.000051539522,0.00014211287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009819411,0.0020275512,0.00068820757,0.0012350285,0.00051769987,0.0006645553,0.0009310494,0.0027015617,0.0053948304],"category_scores_gemma":[0.00046761413,0.0006952851,0.0012168249,0.00034737296,0.0006097778,0.00052467285,0.00062383554,0.003563115,0.0014195747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015491932,0.0020916758,0.00062841305,0.00025319387,0.00006692048,0.00039695116,0.00018599219,0.00019823591,0.9896114,0.0005175487,0.0005408393,0.0039596604],"study_design_scores_gemma":[0.002069581,0.02141984,0.014679869,0.00023425641,0.0003132292,0.0035061175,0.00026419866,0.004822905,0.93426913,0.000667612,0.017691696,0.00006162474],"about_ca_topic_score_codex":0.0011855407,"about_ca_topic_score_gemma":0.0010633675,"teacher_disagreement_score":0.0053948304,"about_ca_system_score_codex":0.00073721743,"about_ca_system_score_gemma":0.0004562287,"threshold_uncertainty_score":0.018047452},"labels":[],"label_agreement":null},{"id":"W3176503729","doi":"10.1172/jci152475","title":"Association of rare predicted loss-of-function variants of influenza-related type I IFN genes with critical COVID-19 pneumonia. Reply.","year":2021,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Odds ratio; Zhàng; Population stratification; Confounding; Case-control study; Population; Genetics; Biology; Genetic association; Pneumonia; Medicine; Genotype; Single-nucleotide polymorphism; Gene; Internal medicine","score_opus":0.06615115426514982,"score_gpt":0.36785602767771086,"score_spread":0.301704873412561,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176503729","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017865308,0.0026104208,0.00033211507,0.9690991,0.024886016,0.000019499428,0.00023633236,0.00006573066,0.00096429256],"genre_scores_gemma":[0.01594653,0.0025280956,0.0006580059,0.9176679,0.058840252,0.00005577754,0.00014204661,0.000051163945,0.0041101454],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984251,0.00055474316,0.00024236068,0.0002820806,0.00032544034,0.00017035623],"domain_scores_gemma":[0.9929397,0.004468614,0.00047760786,0.00026970307,0.0012841121,0.0005601514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002846137,0.00077971636,0.0010668905,0.0006371308,0.0014288131,0.0011692647,0.0015508677,0.017726865,0.0032074694],"category_scores_gemma":[0.01682049,0.0005655416,0.00071874034,0.0005427082,0.0014311683,0.002300261,0.00091010815,0.01621691,0.0034137473],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030285484,0.00006915541,0.0051861564,0.00013343777,0.000052238393,0.00747517,0.0002293392,0.00009981293,0.0009412381,0.0010270108,0.97076774,0.013715787],"study_design_scores_gemma":[0.00063190743,0.00042569026,0.022933792,0.0007164965,0.00030724605,0.04937499,0.0018566028,0.002160086,0.0034933123,0.017747447,0.8999304,0.00042194835],"about_ca_topic_score_codex":0.0030527478,"about_ca_topic_score_gemma":0.0032506972,"teacher_disagreement_score":0.017726865,"about_ca_system_score_codex":0.0013303916,"about_ca_system_score_gemma":0.00079233263,"threshold_uncertainty_score":0.015051961},"labels":[],"label_agreement":null},{"id":"W3179202411","doi":"10.1172/jci141833","title":"WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Exzellenzclusters Entzündungsforschung; Bundesministerium für Bildung und Forschung; Leibniz-Gemeinschaft; Deutsche Forschungsgemeinschaft; Deutsches Zentrum für Infektionsforschung","keywords":"Mycobacterium tuberculosis; Tuberculosis; Virology; Microbiology; Mycobacterium; Biology; Chemistry; Medicine; Pathology","score_opus":0.03839305500355592,"score_gpt":0.34575529528579524,"score_spread":0.3073622402822393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179202411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838845,0.010688298,0.0027043705,0.00042307822,0.00005736418,0.000060726674,0.00031994501,0.00007205174,0.0017896945],"genre_scores_gemma":[0.9912475,0.004492011,0.0014973934,0.000103235536,0.000019854613,0.00004228244,0.000293563,0.000008513756,0.0022956978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990547,0.000023698518,0.000011859269,0.000013804226,0.000021642458,0.000023494838],"domain_scores_gemma":[0.99994385,0.0000039820875,0.00002367968,0.0000051481106,0.000007717197,0.000015541427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014807816,0.0002875704,0.00020035073,0.00013765201,0.00010991566,0.00024420882,0.00009501496,0.000298927,0.0007707837],"category_scores_gemma":[0.000091248294,0.00008226745,0.00018576183,0.00010995811,0.0002571361,0.00016304161,0.0001942174,0.00044027204,0.00022978612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031878246,0.00002403208,0.00036276891,0.00008780089,0.000004747924,0.00008628351,0.000008772351,0.000016881015,0.99748355,0.00006731638,0.00003264226,0.0015064623],"study_design_scores_gemma":[0.000093035385,0.00090047094,0.021178113,0.000025507308,0.00005307871,0.0013198339,0.00007933876,0.0006187869,0.9689229,0.00011088622,0.006691595,0.0000064700303],"about_ca_topic_score_codex":0.00028407804,"about_ca_topic_score_gemma":0.0006180268,"teacher_disagreement_score":0.0007707837,"about_ca_system_score_codex":0.0001696817,"about_ca_system_score_gemma":0.00017571072,"threshold_uncertainty_score":0.002578497},"labels":[],"label_agreement":null},{"id":"W3181088912","doi":"10.1172/jci148979","title":"HLA-E–restricted HIV-1–specific CD8+ T cell responses in natural infection","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Vanderbilt University","keywords":"Immunodominance; Cytotoxic T cell; Epitope; CD8; Biology; Immunology; T cell; Human leukocyte antigen; Subdominant; Virology; Immune system; Major histocompatibility complex; Antigen; In vitro; Genetics","score_opus":0.056818061997560454,"score_gpt":0.33222574136709976,"score_spread":0.2754076793695393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3181088912","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976548,0.00085887307,0.0005173148,0.000029905157,0.000011113006,0.0000326384,0.000036973677,0.000017407876,0.000840988],"genre_scores_gemma":[0.99845386,0.0002985233,0.0005002176,0.000044388835,0.000015631791,0.0000438737,0.000073664545,0.0000033027006,0.0005665039],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998596,0.00005809845,0.000013670465,0.000023667799,0.000011133242,0.00003390608],"domain_scores_gemma":[0.9999304,0.00002785894,0.0000069110947,0.000011166729,0.0000063936013,0.000017189866],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023505377,0.00022562084,0.00018875011,0.00012339398,0.00012610764,0.00023915179,0.000117772324,0.00032098914,0.0015174636],"category_scores_gemma":[0.00022284641,0.000098765166,0.00007216338,0.00005619954,0.00022969213,0.00018727065,0.00014480024,0.00045571168,0.0002375295],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008030256,0.0002509466,0.0021486578,0.0001159524,0.000005479641,0.00024557448,0.000062301115,0.00008926894,0.9898868,0.00008490949,0.00008562597,0.006221458],"study_design_scores_gemma":[0.0005754913,0.0088837035,0.08308259,0.00008778613,0.000066453926,0.0050504063,0.00029446272,0.0041325404,0.890615,0.00064971164,0.006543707,0.000018190012],"about_ca_topic_score_codex":0.00007152288,"about_ca_topic_score_gemma":0.00008692093,"teacher_disagreement_score":0.0015174636,"about_ca_system_score_codex":0.000094123454,"about_ca_system_score_gemma":0.00008253249,"threshold_uncertainty_score":0.005076468},"labels":[],"label_agreement":null},{"id":"W3190418079","doi":"10.1172/jci148278","title":"Interconnections between circadian clocks and metabolism","year":2021,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":160,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institutes of Health; JPB Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; University of Pennsylvania","keywords":"Circadian rhythm; Circadian clock; Bacterial circadian rhythms; Biology; Neuroscience; Adaptation (eye); Oscillating gene; CLOCK","score_opus":0.25298308119546903,"score_gpt":0.4397086976927418,"score_spread":0.18672561649727276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3190418079","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011983572,0.9983713,0.00015548634,0.0003263692,0.00019432328,0.0000029413268,0.000011850473,0.000007991688,0.0008099672],"genre_scores_gemma":[0.00083319587,0.9983712,0.0001461771,0.000103705606,0.00020578172,0.0000048999555,0.00001550642,0.0000010260046,0.00031856445],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99986005,0.00003055344,0.000022049928,0.000025275884,0.00004590129,0.000016109947],"domain_scores_gemma":[0.99981517,0.00007975661,0.000027407028,0.0000070022043,0.00004929526,0.000021288262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004401126,0.0006134447,0.000875713,0.0015134182,0.00023255507,0.00088942423,0.0006166888,0.00080647663,0.0021019783],"category_scores_gemma":[0.00061815814,0.00017788213,0.00033969615,0.001397649,0.0004546779,0.00091635034,0.0007276387,0.0013230994,0.0009498341],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010679366,0.000048806676,0.00034341804,0.01810951,0.00011125072,0.00044077457,0.00013674576,0.00054264726,0.002981924,0.010839435,0.028768009,0.9375707],"study_design_scores_gemma":[0.000012971842,0.00009063611,0.0021489393,0.0036862702,0.000091323454,0.0018036569,0.00008297921,0.00012310487,0.00063043786,0.005085324,0.98622257,0.000021831138],"about_ca_topic_score_codex":0.00096908235,"about_ca_topic_score_gemma":0.001453687,"teacher_disagreement_score":0.0021019783,"about_ca_system_score_codex":0.000626564,"about_ca_system_score_gemma":0.0011835272,"threshold_uncertainty_score":0.007031858},"labels":[],"label_agreement":null},{"id":"W3193668006","doi":"10.1172/jci143328","title":"Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Diabetes Research Center; National Institutes of Health; Joslin Diabetes Center","keywords":"Internal medicine; Endocrinology; Hyperinsulinemia; White adipose tissue; Insulin resistance; Adipose tissue; FOXO1; Adipocyte; Biology; Insulin; Insulin receptor; Brown adipose tissue; PRDM16; Medicine; Protein kinase B; Cell biology; Signal transduction","score_opus":0.10256846651221725,"score_gpt":0.38110390884973705,"score_spread":0.2785354423375198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193668006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.980057,0.0061027175,0.0051228874,0.0003219252,0.0001349569,0.000035164336,0.00065475627,0.00011121195,0.0074593145],"genre_scores_gemma":[0.98828924,0.0031496605,0.002630782,0.00022519378,0.000037437454,0.000049396334,0.00058744644,0.00003986793,0.0049910783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982613,0.000019960318,0.000013161434,0.000056933277,0.000030792355,0.000053132822],"domain_scores_gemma":[0.99990225,0.000009396127,0.000027846016,0.000010544913,0.00001015729,0.000039729075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026454436,0.0002579823,0.00020133946,0.00028901454,0.0001676887,0.00034512632,0.000116076306,0.00019370347,0.0020852487],"category_scores_gemma":[0.00014137765,0.00013706733,0.00034260817,0.00017293164,0.00041797766,0.00033067816,0.00030926487,0.00034607755,0.00024230097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00097280915,0.000031900683,0.0024613424,0.00007052183,0.000014516228,0.00011135675,0.000059634367,0.000050365037,0.98846775,0.0008197721,0.00014101589,0.006798969],"study_design_scores_gemma":[0.00040492715,0.0018597202,0.22534652,0.00018920975,0.00021350292,0.0019468567,0.0007795869,0.0015299668,0.7472941,0.0023957952,0.017975802,0.000063976404],"about_ca_topic_score_codex":0.00023610835,"about_ca_topic_score_gemma":0.00053179625,"teacher_disagreement_score":0.0020852487,"about_ca_system_score_codex":0.00021482342,"about_ca_system_score_gemma":0.00015744752,"threshold_uncertainty_score":0.0069758296},"labels":[],"label_agreement":null},{"id":"W3195517888","doi":"10.1172/jci149236","title":"Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact","funders":"National Center for Complementary and Integrative Health; National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; National Institute of Environmental Health Sciences; U.S. Department of Veterans Affairs","keywords":"Coronavirus disease 2019 (COVID-19); Medicine; Internal medicine; Cohort; Disease; Blood urea nitrogen; Gastroenterology; Kidney; Infectious disease (medical specialty)","score_opus":0.22355113901790874,"score_gpt":0.5100246734373993,"score_spread":0.2864735344194906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195517888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99767977,0.0011209514,0.0005533276,0.00005961361,0.000006249177,0.000009809337,0.00022885732,0.000010194962,0.00033107257],"genre_scores_gemma":[0.9985096,0.0004198963,0.00036806328,0.00002857865,0.000018117944,0.000007924297,0.00053594145,0.0000027020008,0.000109112734],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99973994,0.000072228366,0.000039646253,0.000057771394,0.0000529351,0.000037504473],"domain_scores_gemma":[0.9991154,0.00009630423,0.0005016793,0.00006791285,0.00009581596,0.00012292691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004920784,0.00030147223,0.0003174301,0.00050948246,0.00021249028,0.00046986,0.00011738842,0.00022438278,0.0006748343],"category_scores_gemma":[0.0010626013,0.00011712266,0.00036946282,0.0005364696,0.00024016885,0.00018055248,0.00041781794,0.00059975905,0.00015603725],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076535903,0.000027305687,0.9780447,0.0000336669,0.00008801397,0.00033791145,0.00004634849,0.00014905349,0.014759555,0.00004757879,0.00013223001,0.0055682724],"study_design_scores_gemma":[0.0000069318667,0.00013202865,0.9969593,0.00000973592,0.000031075062,0.0007288259,0.00009491971,0.0005151883,0.0011862505,0.000088390734,0.00024264965,0.0000046512746],"about_ca_topic_score_codex":0.0006881826,"about_ca_topic_score_gemma":0.00051563,"teacher_disagreement_score":0.0006881826,"about_ca_system_score_codex":0.00020663417,"about_ca_system_score_gemma":0.00018902891,"threshold_uncertainty_score":0.0026023984},"labels":[],"label_agreement":null},{"id":"W3196655613","doi":"10.1172/jci138230","title":"T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of California, San Diego; Monash University; Crohn's and Colitis Foundation; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Pfizer; Janssen Pharmaceuticals; Crohn's and Colitis Foundation of America","keywords":"Tight junction; Occludin; Claudin; Protein tyrosine phosphatase; Intestinal permeability; Cell biology; Barrier function; Biology; Inflammatory bowel disease; Paracellular transport; Cancer research; Immunology; Signal transduction; Internal medicine; Medicine; Biochemistry; Permeability (electromagnetism)","score_opus":0.07149544681708048,"score_gpt":0.319902093367877,"score_spread":0.24840664655079653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196655613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960472,0.0024000648,0.0010513157,0.000071396935,0.00001038684,0.000005836416,0.00006190922,0.000019923827,0.00033211734],"genre_scores_gemma":[0.99870896,0.0006824913,0.0003102801,0.000015023158,0.000004304601,0.000004405035,0.000048590624,0.0000024085402,0.00022362155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998952,0.000030931613,0.000008774344,0.000028819777,0.000017047769,0.000019108935],"domain_scores_gemma":[0.99992204,0.000006532832,0.000035430887,0.0000068561953,0.0000094180505,0.000019710518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158281,0.00024260496,0.00019694207,0.00019675476,0.00011235284,0.00026776834,0.00011744519,0.0002494743,0.00063365937],"category_scores_gemma":[0.00019321962,0.00007932875,0.00016413255,0.00012763024,0.0001863208,0.00013949208,0.00016682608,0.00027688977,0.000085106585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005190445,0.000045196266,0.0050046756,0.000075454984,0.000046579393,0.00020302674,0.000032881893,0.0000910259,0.9891395,0.00009996981,0.00006245602,0.004680172],"study_design_scores_gemma":[0.00014242445,0.0019238519,0.1558315,0.000032334578,0.00019887889,0.0032478643,0.00019036028,0.002523653,0.8310804,0.0004646139,0.004352071,0.000012029499],"about_ca_topic_score_codex":0.00042175414,"about_ca_topic_score_gemma":0.0005043895,"teacher_disagreement_score":0.00063365937,"about_ca_system_score_codex":0.00016557271,"about_ca_system_score_gemma":0.0001587329,"threshold_uncertainty_score":0.0021197796},"labels":[],"label_agreement":null},{"id":"W3196745917","doi":"10.1172/jci148013","title":"Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; Centre Hospitalier Universitaire Sainte-Justine; McGill University; McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Epigenetics; Tuberculosis; Immune system; Human immunodeficiency virus (HIV); Innate immune system; Mycobacterium tuberculosis; Chromatin","score_opus":0.06440302404834046,"score_gpt":0.37828296601903383,"score_spread":0.31387994197069335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196745917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99906284,0.0003240453,0.00013511027,0.000021142281,0.0000050104422,0.000011950778,0.00015587786,0.0000037949062,0.00028025603],"genre_scores_gemma":[0.9985876,0.00027956336,0.00022758359,0.000064825195,0.000015085102,0.000027155487,0.0003384748,0.0000019640756,0.00045775445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989665,0.000019045377,0.000013132459,0.000023590748,0.000021280619,0.000026246502],"domain_scores_gemma":[0.99988496,0.00002612139,0.000026296353,0.0000134540915,0.000025414702,0.00002375297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012480334,0.00014831826,0.00016546887,0.00033856247,0.00026613055,0.00030211557,0.000090023525,0.00022235147,0.001453195],"category_scores_gemma":[0.00025229013,0.00012643286,0.00010019902,0.00017422641,0.00015183397,0.00010711755,0.00025420365,0.00021879627,0.00028968984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011368224,0.00016965132,0.13828462,0.00009566561,0.000041551855,0.0007769871,0.0006345725,0.000048131267,0.85013366,0.000055290024,0.00015039193,0.008472695],"study_design_scores_gemma":[0.000022930719,0.00080211443,0.93527335,0.000018700326,0.000047461202,0.002265472,0.0010041503,0.00017115707,0.059146963,0.000118233445,0.0011203376,0.000009229212],"about_ca_topic_score_codex":0.00035010502,"about_ca_topic_score_gemma":0.0005258692,"teacher_disagreement_score":0.001453195,"about_ca_system_score_codex":0.00004612339,"about_ca_system_score_gemma":0.00006599347,"threshold_uncertainty_score":0.0048614144},"labels":[],"label_agreement":null},{"id":"W3196907073","doi":"10.1172/jci146643","title":"Recipient APOL1 risk alleles associate with death-censored renal allograft survival and rejection episodes","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Icahn School of Medicine at Mount Sinai; National Institute of Allergy and Infectious Diseases; National Institute on Aging; National Institutes of Health; American Heart Association","keywords":"Allele; Kidney transplantation; Genotype; Genotyping; Transplantation; SNP; Immune system; Organ transplantation; Transplant rejection","score_opus":0.05349094650339865,"score_gpt":0.3509248290467266,"score_spread":0.297433882543328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196907073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.999398,0.00017729022,0.000117655676,0.000019862919,0.0000024817298,0.0000017621948,0.00009524178,0.000004674985,0.00018302708],"genre_scores_gemma":[0.9995142,0.000047883674,0.0000635497,0.000013618049,0.000008138535,0.000002528834,0.00016520442,0.0000029710743,0.00018191022],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9995945,0.000109827626,0.00003228572,0.000121306126,0.00006170138,0.00008036425],"domain_scores_gemma":[0.9979747,0.00046065892,0.00096425693,0.0002258819,0.00006036494,0.00031419692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079922745,0.00020488085,0.00025348243,0.0003263054,0.00014533557,0.00058621255,0.00022195581,0.00029816362,0.0018387808],"category_scores_gemma":[0.0014932809,0.00013672923,0.00042862011,0.00030368826,0.00020521341,0.00018754386,0.0003618818,0.0008282594,0.00016690594],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014759989,0.000057760906,0.98816866,0.00002071859,0.00020161923,0.00013004376,0.00004210612,0.00018932483,0.0052587274,0.000060850558,0.00013225817,0.0042620255],"study_design_scores_gemma":[0.000025593909,0.00019870976,0.99694747,0.0000062120293,0.00016731302,0.0006296359,0.00005040646,0.0007236416,0.0009045904,0.00012366546,0.00021694823,0.0000058357223],"about_ca_topic_score_codex":0.00047407183,"about_ca_topic_score_gemma":0.00059880776,"teacher_disagreement_score":0.0018387808,"about_ca_system_score_codex":0.00010811326,"about_ca_system_score_gemma":0.00014789557,"threshold_uncertainty_score":0.0061513186},"labels":[],"label_agreement":null},{"id":"W3197836405","doi":"10.1172/jci147076","title":"Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; University of California, San Diego; National Institutes of Health; Novo Nordisk Fonden","keywords":"Kawasaki disease; Medicine; Immunology; Antibody; Immune system; Blockade; Disease; Immunoglobulin G; Intravenous Immunoglobulins; Innate immune system; Receptor; Internal medicine","score_opus":0.034262149722369774,"score_gpt":0.33837545723061013,"score_spread":0.30411330750824034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197836405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977609,0.00088049466,0.00009560442,0.00014234599,0.000017003806,0.000029460016,0.000086465836,0.000006892346,0.0009807652],"genre_scores_gemma":[0.9993623,0.00015876142,0.000101158395,0.000094073715,0.000035242163,0.000014007072,0.000116093535,9.5063143e-7,0.00011730764],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997811,0.0000538214,0.000023018678,0.000045325924,0.000035983496,0.00006075798],"domain_scores_gemma":[0.99962544,0.00007535018,0.0001150058,0.000016202779,0.000044648485,0.0001233405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027820148,0.0003124466,0.0004113641,0.00038793776,0.00032085666,0.0003023654,0.00015745367,0.00047337782,0.001103856],"category_scores_gemma":[0.000891805,0.00009626889,0.00015458373,0.00035771803,0.00019933969,0.00021727597,0.00024286556,0.00039832125,0.00012158768],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015017785,0.00016507437,0.97977644,0.000080450896,0.000042972704,0.005887174,0.00019927023,0.000073420204,0.003963193,0.00006438995,0.0004883448,0.007757498],"study_design_scores_gemma":[0.000110385525,0.0013989402,0.97482103,0.00003472716,0.00007718773,0.020177325,0.00035011666,0.0002909961,0.0010245872,0.000079553756,0.0016264975,0.000008650409],"about_ca_topic_score_codex":0.0006522009,"about_ca_topic_score_gemma":0.00062131113,"teacher_disagreement_score":0.001103856,"about_ca_system_score_codex":0.00033657363,"about_ca_system_score_gemma":0.00024298647,"threshold_uncertainty_score":0.0036927462},"labels":[],"label_agreement":null},{"id":"W3197908941","doi":"10.1172/jci150143","title":"Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute; Sidra Medicine; National Health and Medical Research Council; National Institute of Allergy and Infectious Diseases; NSW Ministry of Health; Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Hospital for Sick Children; US-UK Fulbright Commission; St. Giles Foundation","keywords":"Immunology; Biology; Myeloid; Innate lymphoid cell; T cell; CD8; Cytotoxic T cell; Acquired immune system; CD86; Immunity; Antigen; Immune system; Genetics; In vitro","score_opus":0.06845582114287183,"score_gpt":0.35827299584232297,"score_spread":0.2898171746994511,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197908941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99859387,0.0003024492,0.00039875443,0.00008550789,0.0000131452625,0.000011201111,0.00012370148,0.000031468175,0.00043992692],"genre_scores_gemma":[0.99867696,0.0002983711,0.0004959536,0.000041103274,0.000016895894,0.0000054342677,0.000108096865,0.000013599765,0.0003436019],"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99972254,0.00004507821,0.000029144008,0.00006370848,0.000046083613,0.000093322386],"domain_scores_gemma":[0.9996792,0.000101805905,0.00009437767,0.00001820648,0.000024843477,0.00008167036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019728544,0.0013548132,0.00044079762,0.0005281727,0.00055100746,0.00030561892,0.00032105707,0.000615762,0.0009700929],"category_scores_gemma":[0.00064541394,0.0003102237,0.00034689574,0.0003666862,0.00072876085,0.00027550152,0.0003423659,0.0007191124,0.00027542532],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012747736,0.0011465913,0.09845062,0.00030901848,0.00016307183,0.59057504,0.0019888282,0.0016022694,0.2850804,0.0015002578,0.001328147,0.016581092],"study_design_scores_gemma":[0.0001697448,0.00252016,0.11442329,0.0000854366,0.0002089542,0.8282444,0.0007328228,0.0020959305,0.04617838,0.0003235565,0.004965453,0.00005189707],"about_ca_topic_score_codex":0.0025977644,"about_ca_topic_score_gemma":0.0020191388,"teacher_disagreement_score":0.0025977644,"about_ca_system_score_codex":0.0003142327,"about_ca_system_score_gemma":0.00033285044,"threshold_uncertainty_score":0.005165279},"labels":[],"label_agreement":null},{"id":"W3198585586","doi":"10.1172/jci151788","title":"Convalescent plasma associates with reduced mortality and improved clinical trajectory in patients hospitalized with COVID-19","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Daiichi Sankyo Europe; Moderna; Jounce Therapeutics; Centers for Disease Control and Prevention; AstraZeneca; HCA Healthcare; McGill University; Johns Hopkins University; Pfizer","keywords":"Medicine; Concomitant; Hazard ratio; Internal medicine; Retrospective cohort study; Coronavirus disease 2019 (COVID-19); Cohort study; Risk of mortality; Emergency medicine; Disease; Confidence interval; Infectious disease (medical specialty)","score_opus":0.14799395162123213,"score_gpt":0.4777000822642382,"score_spread":0.3297061306430061,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198585586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9995059,0.00019330058,0.00009659865,0.000046787667,0.000004747262,0.000004128219,0.0000550852,0.0000022054176,0.000091295326],"genre_scores_gemma":[0.99961287,0.00006520199,0.00007837741,0.000021366974,0.000007895745,0.0000027378953,0.00018099023,7.959512e-7,0.000029848597],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99937326,0.00025082027,0.00006365889,0.00012145406,0.000080639846,0.00011025547],"domain_scores_gemma":[0.99767214,0.00050066656,0.0010953229,0.00017295282,0.00016505603,0.0003938106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015360255,0.00031693903,0.0004616032,0.00030735662,0.00029157932,0.000560927,0.00033590867,0.000297114,0.0009159724],"category_scores_gemma":[0.004494986,0.0001137724,0.0006363762,0.00033850584,0.00024664617,0.00038543,0.0005288515,0.00058582355,0.000082454295],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012270479,0.00016880134,0.9942484,0.000020727732,0.00013359524,0.00007179751,0.00006018992,0.00018584606,0.0003249743,0.000030383675,0.000095250405,0.0034328809],"study_design_scores_gemma":[0.000039595692,0.0010493691,0.9971631,0.000011544066,0.00006115623,0.0001500299,0.00013476568,0.0011136294,0.00010261226,0.00007511349,0.00009386392,0.0000050382487],"about_ca_topic_score_codex":0.0021041918,"about_ca_topic_score_gemma":0.002367938,"teacher_disagreement_score":0.0021041918,"about_ca_system_score_codex":0.00030021367,"about_ca_system_score_gemma":0.00040295147,"threshold_uncertainty_score":0.008123398},"labels":[],"label_agreement":null},{"id":"W3198689752","doi":"10.1172/jci153285","title":"CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American Diabetes Association; American Heart Association; Novo Nordisk; University of Washington; National Institutes of Health","keywords":"Hypertriglyceridemia; Dyslipidemia; Apolipoprotein B; Pathogenesis; Diabetes mellitus; Cholesterol; Lipoprotein; Apolipoprotein E","score_opus":0.05760651148398602,"score_gpt":0.3491855575332442,"score_spread":0.2915790460492582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198689752","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916027,0.0027428707,0.0021152531,0.00044946256,0.00015517065,0.000055841512,0.00019526864,0.00037164483,0.0023118146],"genre_scores_gemma":[0.98876953,0.002721618,0.0024308534,0.00036931477,0.000117036354,0.00008438797,0.00038592838,0.000075840355,0.005045605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999254,0.000013585377,0.000005486005,0.00000813797,0.000020302588,0.000027201644],"domain_scores_gemma":[0.9999151,0.0000092381415,0.0000200683,0.000009271115,0.000009235322,0.0000371515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016771398,0.00045269672,0.00038074364,0.0004391883,0.000116050076,0.00025493154,0.00038713202,0.00037528705,0.0016911993],"category_scores_gemma":[0.00018580152,0.00012502835,0.00023302363,0.00015276819,0.00038736328,0.00018720994,0.00021822604,0.0009162988,0.00028188084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008902036,0.002505476,0.0007256908,0.00031720233,0.000072160496,0.00028385525,0.000049400034,0.00036301534,0.92103714,0.0007761107,0.00066519185,0.06430274],"study_design_scores_gemma":[0.0039457837,0.016335554,0.021949625,0.00008944953,0.00025076815,0.0010361904,0.00015865405,0.0037261543,0.93665475,0.0011715583,0.0146383345,0.00004316176],"about_ca_topic_score_codex":0.00054380856,"about_ca_topic_score_gemma":0.0007672211,"teacher_disagreement_score":0.0016911993,"about_ca_system_score_codex":0.00019580439,"about_ca_system_score_gemma":0.00032881869,"threshold_uncertainty_score":0.0056576133},"labels":[],"label_agreement":null},{"id":"W3202259720","doi":"10.1172/jci152386","title":"Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Cilag; National Institute of Diabetes and Digestive and Kidney Diseases; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health; Grifols; Junta de Castilla y León; National Center for Advancing Translational Sciences; Consejo Superior de Investigaciones Científicas; Regione Toscana; Science for Life Laboratory; Fonds Léon Fredericq; Magnus Bergvalls Stiftelse; Norges Forskningsråd; NordForsk; Vetenskapsrådet; Technische Universität München; Ministero della Salute; Fonds Erasme; Fonds De La Recherche Scientifique - FNRS; King's College London; Jewish General Hospital; Public Health Agency of Canada; Bundesministerium für Bildung und Forschung; Helsingin Yliopisto; European Commission; Cancer Research UK; Deutsche Forschungsgemeinschaft; McGill University; Dipartimenti di Eccellenza; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico; Ministero dell’Istruzione, dell’Università e della Ricerca; ViiV Healthcare; Humanitas University; Public Health Agency; Japan Society for the Promotion of Science; GlaxoSmithKline; Biogen; Instituto de Salud Carlos III; Waalse Gewest; Università degli Studi di Siena; Associazione Italiana per la Ricerca sul Cancro; Eli Lilly and Company","keywords":"Odds ratio; Risk factor; Respiratory failure; Allele; Case-control study; Odds; Risk of mortality; Genetic predisposition; Respiratory system","score_opus":0.22704685058319835,"score_gpt":0.5363378615330497,"score_spread":0.3092910109498514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202259720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7201408,0.26720187,0.0030353933,0.0009893775,0.00044929286,0.00006513043,0.0050997194,0.00006730584,0.002951117],"genre_scores_gemma":[0.9859502,0.011191387,0.0007693415,0.00034640465,0.00015031447,0.000035029494,0.0012274589,0.000017418393,0.00031256067],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99764556,0.0009642409,0.00030725653,0.00068974966,0.0002103103,0.00018286651],"domain_scores_gemma":[0.99513865,0.0027629822,0.0010105007,0.0006015182,0.00031594385,0.00017041422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004225323,0.00082953746,0.0013619795,0.0010597495,0.00038928757,0.001106867,0.00061236083,0.00075239904,0.0015557047],"category_scores_gemma":[0.0076210117,0.00043139292,0.005617311,0.0013173084,0.00037823833,0.0006090065,0.00073103997,0.00090026995,0.00012249713],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041961353,0.000034550372,0.88082796,0.0024279312,0.09006873,0.00025137138,0.0001082246,0.0011831371,0.000992763,0.0002937255,0.0013755633,0.018239914],"study_design_scores_gemma":[0.000273953,0.00044471835,0.92174655,0.0006923569,0.07005926,0.0005645568,0.00010664256,0.0011056997,0.0005317886,0.0008679638,0.0035714058,0.00003502674],"about_ca_topic_score_codex":0.006834932,"about_ca_topic_score_gemma":0.009483885,"teacher_disagreement_score":0.006834932,"about_ca_system_score_codex":0.00038140497,"about_ca_system_score_gemma":0.0003142851,"threshold_uncertainty_score":0.02234596},"labels":[],"label_agreement":null},{"id":"W3203824213","doi":"10.1172/jci152310","title":"Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital herpes in preclinical models","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Perelman School of Medicine, University of Pennsylvania; Center for AIDS Research, University of Washington; University of Pennsylvania; National Institute of Neurological Disorders and Stroke; BioNTech","keywords":"Titer; Immunization; Immune system; Antibody; Antigen; Sex organ; Messenger RNA; Immunity","score_opus":0.1411948163975165,"score_gpt":0.3809080664430161,"score_spread":0.23971325004549962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203824213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939102,0.0015671444,0.002385062,0.00016348189,0.00012207651,0.00018096916,0.00027036783,0.00013591268,0.0012648591],"genre_scores_gemma":[0.99177027,0.0019720083,0.0027851856,0.00012514762,0.000069556365,0.00026696935,0.00066983793,0.00003419806,0.002306887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99968886,0.00007291627,0.000022907152,0.000052177893,0.00005699842,0.00010621515],"domain_scores_gemma":[0.99974126,0.00004871782,0.00006852293,0.00004260134,0.000036168807,0.000062768195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062448427,0.0006376417,0.0006724836,0.00057109795,0.0001710831,0.0004160112,0.00041082408,0.00064120186,0.0014508636],"category_scores_gemma":[0.00034751688,0.00022874559,0.00027732094,0.00020000279,0.0003837433,0.00042735372,0.00015919612,0.0013322327,0.0003908037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019149993,0.0023011395,0.00034626658,0.00015389895,0.000033597942,0.00006347145,0.00006605157,0.0004984672,0.9858359,0.00016121475,0.0002164554,0.008408498],"study_design_scores_gemma":[0.00056126894,0.06368291,0.0032934858,0.000045713292,0.000115835945,0.00032352688,0.00006401505,0.0011047362,0.92789745,0.00014828322,0.0027509106,0.000011830689],"about_ca_topic_score_codex":0.00051736174,"about_ca_topic_score_gemma":0.0008278725,"teacher_disagreement_score":0.0014508636,"about_ca_system_score_codex":0.00029476595,"about_ca_system_score_gemma":0.00035285013,"threshold_uncertainty_score":0.004853606},"labels":[],"label_agreement":null},{"id":"W3208032032","doi":"10.1172/jci146915","title":"Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto; University Health Network; SickKids Foundation; Princess Margaret Cancer Centre; Toronto Western Hospital; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Universität Innsbruck; Brain Tumour Charity","keywords":"DNA methylation; Promoter; Allele; Biology; Methylation; Cancer research; Gene; Cancer; Molecular biology; Genetics; Gene expression","score_opus":0.10170227446877773,"score_gpt":0.378755792079373,"score_spread":0.27705351761059527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3208032032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99476504,0.0029941895,0.0015215699,0.00003654168,0.0000046171012,0.000008613221,0.00016509839,0.00002207259,0.0004822389],"genre_scores_gemma":[0.9983942,0.0005815536,0.0005182557,0.000018395798,0.0000044074527,0.0000050131616,0.00013569974,0.000003962558,0.00033848058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998621,0.000027543994,0.0000133136145,0.000043274886,0.00003363727,0.000020120046],"domain_scores_gemma":[0.9997003,0.000081540005,0.00010160185,0.000036683523,0.000030359115,0.000049429782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028825254,0.00011424477,0.00018615492,0.00041540113,0.00013057131,0.0002648033,0.000119095675,0.00015108082,0.00077580486],"category_scores_gemma":[0.00050124095,0.00010457987,0.000121098004,0.0002266333,0.00016434836,0.00013979888,0.00022215015,0.00021355906,0.00010954973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046497775,0.000026820417,0.0930207,0.000107460146,0.000068273526,0.0004236191,0.00016855466,0.00020349867,0.8880091,0.00022455561,0.00006714476,0.017215298],"study_design_scores_gemma":[0.000018581026,0.0005069979,0.60735154,0.000027760152,0.0001621964,0.0072977664,0.00018239798,0.0016094132,0.37832814,0.00074775034,0.003748949,0.000018476947],"about_ca_topic_score_codex":0.00036277057,"about_ca_topic_score_gemma":0.0008498993,"teacher_disagreement_score":0.00077580486,"about_ca_system_score_codex":0.00012797731,"about_ca_system_score_gemma":0.00017772174,"threshold_uncertainty_score":0.002595365},"labels":[],"label_agreement":null},{"id":"W3211273620","doi":"10.1172/jci153606","title":"CDKL5 deficiency disorder: a pathophysiology of neural maintenance","year":2021,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Simons Initiative for the Developing Brain","keywords":"Rett syndrome; Neuroscience; Pathophysiology; Genetic disorder; Intervention (counseling); Biology; Bioinformatics; Medicine; Psychology; Genetics; Psychiatry; Endocrinology; Gene","score_opus":0.03653298499632493,"score_gpt":0.3075129049238657,"score_spread":0.2709799199275408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3211273620","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016633678,0.0101699615,0.00088075054,0.94009924,0.017314732,0.00006678149,0.00013095846,0.00016297841,0.014540912],"genre_scores_gemma":[0.17259829,0.020628018,0.0029887813,0.6625971,0.10968089,0.0001487137,0.00013149131,0.00007384391,0.031152926],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99968934,0.000066608,0.000042068237,0.000058375896,0.00008758906,0.000056072447],"domain_scores_gemma":[0.99920315,0.00037537227,0.00009945455,0.00004685734,0.00013317897,0.00014200603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039989201,0.00053226604,0.0005826973,0.00038355184,0.0010770048,0.00088602054,0.0008409751,0.01073377,0.0024831411],"category_scores_gemma":[0.0025770015,0.00023745137,0.0003916133,0.00033170273,0.0012958971,0.0012555257,0.00040708075,0.007873957,0.0018586772],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003290769,0.0001639757,0.008178259,0.00027306617,0.000050996554,0.23137462,0.00042722965,0.0003174276,0.0046967617,0.015937617,0.68577516,0.05247585],"study_design_scores_gemma":[0.00036270625,0.00031702698,0.009760412,0.0004841748,0.00009019402,0.38946682,0.00062626944,0.0027519849,0.003584748,0.02959616,0.56287175,0.00008783956],"about_ca_topic_score_codex":0.0013945344,"about_ca_topic_score_gemma":0.002038267,"teacher_disagreement_score":0.01073377,"about_ca_system_score_codex":0.0016171079,"about_ca_system_score_gemma":0.00073239027,"threshold_uncertainty_score":0.011732936},"labels":[],"label_agreement":null},{"id":"W3211329272","doi":"10.1172/jci154699","title":"Deprogram and reprogram to solve the riddle of insulin resistance","year":2021,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Induced pluripotent stem cell; Insulin resistance; Insulin; Epigenetics; Biology; Population; Basal (medicine); Cell biology; Bioinformatics; Endocrinology; Internal medicine; Genetics; Embryonic stem cell; Medicine; Gene","score_opus":0.11255427241093617,"score_gpt":0.3760682153526361,"score_spread":0.26351394294169994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3211329272","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003450006,0.015963456,0.0009859193,0.91981924,0.051826302,0.00003613696,0.00006146582,0.00019344779,0.007664033],"genre_scores_gemma":[0.022021512,0.0141598005,0.0014328146,0.83564955,0.108060405,0.00006405545,0.00007483095,0.00007836914,0.018458609],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99903643,0.0003238313,0.00012487869,0.00010391305,0.00031710116,0.00009382231],"domain_scores_gemma":[0.9973695,0.001426835,0.00014931534,0.00022523788,0.00047590907,0.00035306675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015909206,0.0005409136,0.0006510901,0.0003785982,0.00088119926,0.0012349931,0.0007183299,0.009766664,0.0033329383],"category_scores_gemma":[0.008096828,0.00026010882,0.00066614116,0.0002047264,0.0017404801,0.0014786103,0.0006660485,0.014429993,0.005212957],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021908531,0.00016945187,0.0014243053,0.00022802528,0.00003823717,0.009384265,0.0001552561,0.00014971684,0.0042551938,0.0070800697,0.90997124,0.06692515],"study_design_scores_gemma":[0.00013754275,0.00021198706,0.0014641734,0.00017441506,0.000029033352,0.010838625,0.0002104082,0.0005099851,0.002776439,0.010520957,0.9730881,0.000038236194],"about_ca_topic_score_codex":0.0005629497,"about_ca_topic_score_gemma":0.0010226648,"teacher_disagreement_score":0.009766664,"about_ca_system_score_codex":0.0012205156,"about_ca_system_score_gemma":0.00076542026,"threshold_uncertainty_score":0.011149824},"labels":[],"label_agreement":null},{"id":"W3213661748","doi":"10.1172/jci144871","title":"Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Terry Fox Research Institute; Canadian Institutes of Health Research; McGill University Health Centre; Genome Canada; Cancer Research Society; Terry Fox Foundation; Deutsches Krebsforschungszentrum; McGill University","keywords":"Folliculin; Warburg effect; Angiogenesis; AMPK; Anaerobic glycolysis; TFE3; Cancer; Suppressor; Tumor progression","score_opus":0.03735209683478685,"score_gpt":0.32401216258102694,"score_spread":0.2866600657462401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213661748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942848,0.002011329,0.0010166726,0.00013756727,0.00003757746,0.000026382177,0.00056169875,0.00018401233,0.0017399879],"genre_scores_gemma":[0.9959753,0.0006822853,0.0006250982,0.00006791714,0.000008993883,0.000048438862,0.0004132805,0.000026806767,0.0021518643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998658,0.00002202471,0.000010918879,0.00002444082,0.000031363128,0.000045417128],"domain_scores_gemma":[0.99991286,0.000011242121,0.000026230686,0.00001035494,0.000005605309,0.000033676337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013802752,0.00031269662,0.00028325073,0.00033530153,0.00013287496,0.00020538844,0.00018576237,0.00027466513,0.0012268942],"category_scores_gemma":[0.000093495386,0.000121344325,0.0002120535,0.00016178782,0.00024035462,0.00010599468,0.00016303851,0.0003966168,0.0002755346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002580477,0.00004946032,0.00013829974,0.000019001105,0.000006640191,0.00003530737,0.0000075885237,0.000058309743,0.9983651,0.000074510404,0.00005916267,0.0009285532],"study_design_scores_gemma":[0.000054776403,0.00044533305,0.005989977,0.000005983976,0.000018247825,0.00018958322,0.00002721263,0.0009657745,0.9883526,0.000067535664,0.0038772412,0.0000056597523],"about_ca_topic_score_codex":0.001003676,"about_ca_topic_score_gemma":0.0011103341,"teacher_disagreement_score":0.0012268942,"about_ca_system_score_codex":0.00036576745,"about_ca_system_score_gemma":0.00027462927,"threshold_uncertainty_score":0.004104376},"labels":[],"label_agreement":null},{"id":"W3217129431","doi":"10.1172/jci152042","title":"SARS-CoV-2–specific memory B cells can persist in the elderly who have lost detectable neutralizing antibodies","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Public Health England; Horizon 2020; National Institute for Health and Care Research; UK Coronavirus Immunology Consortium; UK Research and Innovation; Wellcome Trust; Francis Crick Institute; Cancer Research UK","keywords":"Asymptomatic; Antibody; Cohort; Immunity; Humoral immunity; Immune system; Isotype; Outbreak","score_opus":0.16379623193140794,"score_gpt":0.41788050513165176,"score_spread":0.25408427320024385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3217129431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9995932,0.00016618441,0.00004477744,0.000006553287,0.00000225723,0.0000031432762,0.00003351386,0.0000018548142,0.0001484412],"genre_scores_gemma":[0.99944204,0.00008411562,0.00004649827,0.00003096652,0.000013073567,0.0000051488646,0.00012668877,0.000001330101,0.00025009876],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998791,0.000016798891,0.000009755656,0.000027942255,0.000016147897,0.000050257604],"domain_scores_gemma":[0.9997714,0.00003059342,0.00006016098,0.000028818271,0.000047481903,0.00006155595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032404266,0.0002604284,0.0003241539,0.0004388964,0.00026036362,0.00028716904,0.00014342854,0.00023784088,0.0010099617],"category_scores_gemma":[0.0005078403,0.00012943937,0.00019116208,0.00018890855,0.00015334935,0.00026944524,0.00024958994,0.00023434465,0.0002806591],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002125984,0.00038940264,0.7815323,0.00008394777,0.00008830239,0.0024059962,0.00092264474,0.00013774281,0.19182895,0.00009733664,0.00036786665,0.02001962],"study_design_scores_gemma":[0.00003840367,0.0021436147,0.9811428,0.000014786475,0.00007677412,0.003810185,0.0005946891,0.0002717032,0.0102618765,0.00008091776,0.0015556907,0.000008594232],"about_ca_topic_score_codex":0.00083112495,"about_ca_topic_score_gemma":0.0006296749,"teacher_disagreement_score":0.0010099617,"about_ca_system_score_codex":0.00010014371,"about_ca_system_score_gemma":0.000093316805,"threshold_uncertainty_score":0.0033786893},"labels":[],"label_agreement":null},{"id":"W3217459667","doi":"10.1172/jci150823","title":"Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; Wellcome Trust; National Institutes of Health; Centre Hospitalier Universitaire Vaudois; Brigham and Women's Hospital; Medical Research Council; HIV Vaccine Trials Network","keywords":"Epitope; Priming (agriculture); Modified vaccinia Ankara; Heterologous; Immune system; Vaccination; Vaccinia; Antigen; DNA vaccination","score_opus":0.08704776980235726,"score_gpt":0.3898604170003496,"score_spread":0.3028126471979924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3217459667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99792045,0.0007764162,0.00009144445,0.000084997024,0.00003239899,0.00019684585,0.000038646347,0.000008526287,0.0008503514],"genre_scores_gemma":[0.9979798,0.00023812069,0.00018492069,0.00020490692,0.00008558344,0.00015370444,0.00010594926,0.000004109415,0.0010430263],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9996112,0.00020770456,0.000022943279,0.00004757387,0.00003154888,0.00007895246],"domain_scores_gemma":[0.99934274,0.00023367765,0.00006637721,0.00005692464,0.00004380418,0.00025639025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018554333,0.00033118075,0.0006562568,0.000075746335,0.00026506925,0.0004133165,0.00024777043,0.0005920945,0.0022219275],"category_scores_gemma":[0.0015523457,0.0002199991,0.00021860798,0.00007027873,0.0002317624,0.0003868199,0.00018536656,0.00092284376,0.0003793625],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.42686525,0.028658839,0.084702216,0.0011356208,0.000761887,0.00089800905,0.0010976006,0.0023370883,0.1320742,0.0006717722,0.003876814,0.3169207],"study_design_scores_gemma":[0.045138326,0.6788235,0.22784242,0.000232923,0.00084407086,0.0010192683,0.00017113189,0.0034477436,0.03326644,0.0010730656,0.008091631,0.000049510694],"about_ca_topic_score_codex":0.00013255618,"about_ca_topic_score_gemma":0.00036161987,"teacher_disagreement_score":0.0022219275,"about_ca_system_score_codex":0.00022884508,"about_ca_system_score_gemma":0.0005415618,"threshold_uncertainty_score":0.009812593},"labels":[],"label_agreement":null},{"id":"W4200227253","doi":"10.1172/jci153876","title":"BACH2 inhibition reverses β cell failure in type 2 diabetes models","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; Diabetes Research Center; Albert Einstein College of Medicine, Yeshiva University; York University","keywords":"Islet; Type 2 diabetes; Endocrinology; Insulin; Diabetes mellitus; Progenitor cell; Internal medicine; Biology; Cell type; Glucose homeostasis; Cell; Stem cell; Cell biology; Medicine; Insulin resistance","score_opus":0.08555146307972826,"score_gpt":0.3402142870651975,"score_spread":0.25466282398546924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200227253","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98296136,0.0052454877,0.006150692,0.0005958897,0.00030792112,0.0001323534,0.001020247,0.00046019457,0.0031258557],"genre_scores_gemma":[0.98791856,0.0034618066,0.0035070472,0.00029923103,0.00006638842,0.00015267245,0.0010634137,0.000057011566,0.0034738448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998166,0.000036441434,0.000020417145,0.0000327095,0.00004030711,0.00005366959],"domain_scores_gemma":[0.99986005,0.000013067066,0.000034055167,0.000016793461,0.000014929292,0.000061070976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039465667,0.0004858924,0.00045551476,0.00040625094,0.00021224549,0.0004163246,0.00030480648,0.0002873794,0.0018804183],"category_scores_gemma":[0.00019359934,0.00016132629,0.0003551905,0.0001888142,0.00035205344,0.00029359947,0.00025776177,0.0013023268,0.00026557568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016656917,0.00038006317,0.00076639606,0.00017255625,0.00004307033,0.00009969794,0.00003428987,0.00016898454,0.98628205,0.00040418777,0.0005147416,0.00946831],"study_design_scores_gemma":[0.00052519416,0.0056653987,0.0113620255,0.000047294485,0.000118491036,0.0005491375,0.00011452269,0.00164413,0.97069764,0.0003596662,0.008894659,0.00002171505],"about_ca_topic_score_codex":0.00034647583,"about_ca_topic_score_gemma":0.00079142256,"teacher_disagreement_score":0.0018804183,"about_ca_system_score_codex":0.00020505655,"about_ca_system_score_gemma":0.0002600136,"threshold_uncertainty_score":0.0062906146},"labels":[],"label_agreement":null},{"id":"W4205523133","doi":"10.1172/jci136227","title":"The multifaceted nature of HIV latency","year":2020,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Virus latency; Virology; Biology; Viral replication; Human immunodeficiency virus (HIV); Latency (audio); Latent Virus; Virus; Genome; Antiretroviral therapy; Immunology; Viral load; Genetics; Gene; Computer science","score_opus":0.12223615851477383,"score_gpt":0.44155956335161284,"score_spread":0.319323404836839,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205523133","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008661971,0.9983266,0.00014422645,0.0005232987,0.00023574349,0.000003812336,0.000009232406,0.0000056125045,0.0006648531],"genre_scores_gemma":[0.0006545821,0.99844617,0.00010733614,0.00022888223,0.00021623871,0.000004140674,0.000013597504,8.7212663e-7,0.00032826353],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997154,0.000059582988,0.000032027838,0.000044035336,0.0001126563,0.000036272188],"domain_scores_gemma":[0.9996803,0.0001710428,0.00004644783,0.000009088845,0.000061389714,0.000031794818],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007570526,0.00070797524,0.0011828814,0.0013514516,0.00037486458,0.001610089,0.0011075775,0.0013360375,0.0023165739],"category_scores_gemma":[0.000647571,0.0003018841,0.00040199998,0.001006054,0.0011304957,0.0020012837,0.0008682197,0.0024931415,0.001514997],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008640119,0.000034269833,0.00024494453,0.015509936,0.000062083054,0.00033893454,0.000121298435,0.00037134206,0.0037572745,0.016848918,0.024275867,0.93834865],"study_design_scores_gemma":[0.000011717896,0.00009022628,0.0007284847,0.003828312,0.00007074692,0.0020634378,0.00010226854,0.00011277446,0.0010911755,0.008090525,0.9837848,0.00002559487],"about_ca_topic_score_codex":0.0009756613,"about_ca_topic_score_gemma":0.0015394461,"teacher_disagreement_score":0.0023165739,"about_ca_system_score_codex":0.0009834152,"about_ca_system_score_gemma":0.0018299051,"threshold_uncertainty_score":0.0077496767},"labels":[],"label_agreement":null},{"id":"W4205838182","doi":"10.1172/jci142338","title":"JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Williams Syndrome Research","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Center for Advancing Translational Sciences; Canadian Institutes of Health Research; March of Dimes Foundation; Yale University; National Institutes of Health; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"Elastin; Supravalvular aortic stenosis; JAG1; Aorta; Notch signaling pathway; Vascular smooth muscle; Downregulation and upregulation; Phenotype","score_opus":0.13803040536157357,"score_gpt":0.38460582894342166,"score_spread":0.24657542358184809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205838182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99734265,0.0006936996,0.0009962996,0.00008097889,0.00002377664,0.000014051959,0.00020187239,0.000054376036,0.00059236324],"genre_scores_gemma":[0.99662066,0.00042876275,0.00069014693,0.00008559951,0.000007222063,0.000026236561,0.00029341984,0.000014420417,0.0018334494],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99982953,0.00002874142,0.000027994562,0.000039235776,0.000036343303,0.000038139468],"domain_scores_gemma":[0.99985766,0.000012552455,0.0000340893,0.000013439041,0.000009810474,0.00007245275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018367174,0.0002926278,0.00025529982,0.00032468772,0.00018585396,0.00025941237,0.00018861554,0.0003692269,0.0012076476],"category_scores_gemma":[0.000113951006,0.00023827188,0.00030469522,0.00013439682,0.00029621285,0.00017472134,0.00028214406,0.00087133865,0.00033702012],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019413156,0.00004665671,0.00037239311,0.000029838264,0.000004604282,0.00011343558,0.00002167094,0.000030788073,0.99850464,0.00006345634,0.0000293527,0.0005890221],"study_design_scores_gemma":[0.00006360024,0.0004686919,0.019722855,0.000017957758,0.000032297157,0.0008575776,0.00010376026,0.0012592206,0.9750965,0.000117428084,0.0022511042,0.0000089776595],"about_ca_topic_score_codex":0.00042790975,"about_ca_topic_score_gemma":0.0008748765,"teacher_disagreement_score":0.0012076476,"about_ca_system_score_codex":0.00020637426,"about_ca_system_score_gemma":0.00018450816,"threshold_uncertainty_score":0.004040003},"labels":[],"label_agreement":null},{"id":"W4206120828","doi":"10.1172/jci200215883","title":"EphB6 crosslinking results in costimulation of T cells","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Roche Organ Transplant Research Foundation; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"CD28; T cell; Biology; T-cell receptor; Cell biology; Molecular biology; Immunology; Immune system","score_opus":0.27908655831452694,"score_gpt":0.4060633871174051,"score_spread":0.12697682880287814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206120828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98947644,0.0025124252,0.001987854,0.00019526774,0.00017407052,0.00008808913,0.00049614965,0.00011642391,0.0049532265],"genre_scores_gemma":[0.987671,0.0011664556,0.0029636908,0.00017989917,0.000075070704,0.00013257345,0.0010158117,0.000040784766,0.006754763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995478,0.00007924571,0.000039605984,0.00009167414,0.00009369199,0.00014801348],"domain_scores_gemma":[0.9998337,0.00003933804,0.00002314457,0.000022320366,0.000013421978,0.000067991816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014713782,0.00062893354,0.00031437172,0.0001950412,0.00012805715,0.00027016294,0.00018736119,0.00044475478,0.0033932324],"category_scores_gemma":[0.00013839759,0.00017965504,0.0003053332,0.00017298771,0.00010502118,0.00021980683,0.00035242652,0.0011815424,0.0011852679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002807948,0.0000882754,0.0000778202,0.000051975658,0.0000075367566,0.00009808972,0.000016591644,0.000057331894,0.99748707,0.00009895451,0.00013578142,0.001599839],"study_design_scores_gemma":[0.00005473136,0.0005669644,0.0030775005,0.000009629671,0.000025844216,0.000570467,0.000013407509,0.00080050586,0.98879796,0.00005108724,0.0060274135,0.0000044611234],"about_ca_topic_score_codex":0.00021262646,"about_ca_topic_score_gemma":0.0003133896,"teacher_disagreement_score":0.0033932324,"about_ca_system_score_codex":0.00023241964,"about_ca_system_score_gemma":0.00015306185,"threshold_uncertainty_score":0.011351466},"labels":[],"label_agreement":null},{"id":"W4206210836","doi":"10.1172/jci153397","title":"Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Prevention of Organ Failure","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Vanderbilt University Medical Center; Vanderbilt University; U.S. Department of Veterans Affairs","keywords":"FOXP3; Androgen receptor; Eosinophil; Allergic inflammation; Signal transduction; Inflammation; Receptor; Airway","score_opus":0.04380437728580577,"score_gpt":0.2877971410220952,"score_spread":0.24399276373628942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206210836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9679966,0.022730332,0.0013839176,0.00046464446,0.00020298369,0.000047926285,0.000739238,0.00013447234,0.0062998915],"genre_scores_gemma":[0.99432474,0.0022154876,0.0002635121,0.00016420646,0.000069865,0.000029042101,0.000178704,0.000011696084,0.00274275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989045,0.000022558901,0.000005784192,0.000021839664,0.000022980306,0.00003626571],"domain_scores_gemma":[0.99995005,0.000004260648,0.000011857808,0.000004074427,0.000005834555,0.000023985249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013143725,0.00019520546,0.00019295175,0.00018447156,0.00015553011,0.00024893708,0.00007748075,0.00014965222,0.0034815792],"category_scores_gemma":[0.000112477624,0.0000867458,0.00017839119,0.00013105129,0.00015007463,0.0001059395,0.00011672005,0.000440458,0.00038216056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002449826,0.00023120626,0.01405384,0.00023801309,0.000044445525,0.0005348976,0.00013010079,0.00013578907,0.9361235,0.00041148395,0.0012392438,0.04440779],"study_design_scores_gemma":[0.0005298855,0.006193941,0.5478796,0.00010053125,0.0002641764,0.0047078524,0.0005029687,0.0011495908,0.3783081,0.00081136025,0.059512366,0.00003976776],"about_ca_topic_score_codex":0.0005333196,"about_ca_topic_score_gemma":0.0011160978,"teacher_disagreement_score":0.0034815792,"about_ca_system_score_codex":0.00013207018,"about_ca_system_score_gemma":0.00025650044,"threshold_uncertainty_score":0.011646986},"labels":[],"label_agreement":null},{"id":"W4206485610","doi":"10.1172/jci149473","title":"ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre","funders":"Fundo para o Desenvolvimento das Ciências e da Tecnologia; Zhejiang University; Faculdade de Ciências da Saúde, Universidade de Macau; Universidade de Macau","keywords":"Metastasis; Breast cancer; Cancer; Cancer cell; Phosphatidylserine; Cytotoxic T cell; Phenotype; Paclitaxel; Suppressor","score_opus":0.05541416520638173,"score_gpt":0.38852334427172813,"score_spread":0.33310917906534643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206485610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99145925,0.0014962357,0.003735595,0.00044610916,0.00010763213,0.00007667176,0.00059445144,0.00020082685,0.0018831372],"genre_scores_gemma":[0.98939276,0.0014357865,0.0019676806,0.000093444316,0.000020012038,0.000117482516,0.0007151951,0.00003287601,0.0062247696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999846,0.000039699193,0.00001629603,0.0000257097,0.000034657143,0.00003761904],"domain_scores_gemma":[0.9999119,0.000009716662,0.000023131595,0.000011117347,0.000008551299,0.000035599878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002005931,0.000503049,0.0003175539,0.00038450718,0.00017385038,0.00028510147,0.00029961177,0.00045036516,0.0019015489],"category_scores_gemma":[0.00007650704,0.00018014254,0.00021037536,0.00020021324,0.00026774945,0.00023858515,0.0001390923,0.0010775329,0.00035464086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004088837,0.00021723354,0.00015899741,0.000041575124,0.0000074636405,0.00003190233,0.000009983531,0.00007682704,0.9972662,0.00011804061,0.00011252401,0.0015504104],"study_design_scores_gemma":[0.00012924169,0.0021676123,0.0024736868,0.000011632883,0.000027379165,0.00017058356,0.00004196768,0.0016176571,0.98967826,0.00008382811,0.0035924031,0.000005870304],"about_ca_topic_score_codex":0.0006775897,"about_ca_topic_score_gemma":0.0013224763,"teacher_disagreement_score":0.0019015489,"about_ca_system_score_codex":0.00027281136,"about_ca_system_score_gemma":0.00024156216,"threshold_uncertainty_score":0.006361246},"labels":[],"label_agreement":null},{"id":"W4210271223","doi":"10.1172/jci200113712","title":"Glypicans: proteoglycans with a surprise","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":359,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institutes of Health; March of Dimes Foundation","keywords":"Surprise; Medicine; Biology; Psychology; Communication","score_opus":0.06160935707868281,"score_gpt":0.37683067240409834,"score_spread":0.31522131532541553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210271223","genre_codex":"commentary","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23106693,0.2626178,0.019376997,0.38171095,0.07503575,0.000111274574,0.0007823029,0.0013174439,0.027980592],"genre_scores_gemma":[0.6510221,0.096271925,0.016232712,0.13005877,0.062416345,0.0001611112,0.00085627753,0.0003746705,0.042606086],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99962103,0.00007377127,0.000037640537,0.00005845697,0.00014021507,0.00006878088],"domain_scores_gemma":[0.9992138,0.00016546976,0.00009169055,0.00010176996,0.00014482827,0.00028237802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010060132,0.001104725,0.0006575261,0.00060967903,0.00090331765,0.0019464903,0.0005085827,0.00270891,0.0011820225],"category_scores_gemma":[0.0024245752,0.00025803814,0.0004506866,0.000367468,0.0021688207,0.0027905672,0.0018223365,0.0036394917,0.0012303471],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0043583554,0.0002201516,0.012034937,0.0010284941,0.00029168854,0.04067541,0.0021392074,0.00078894,0.19796954,0.09353745,0.28998032,0.3569754],"study_design_scores_gemma":[0.00029873953,0.0008187824,0.007255281,0.00029433248,0.00020403978,0.069928005,0.0016034208,0.0012986762,0.05694758,0.09419965,0.7670109,0.00014069986],"about_ca_topic_score_codex":0.00018231463,"about_ca_topic_score_gemma":0.00013136069,"teacher_disagreement_score":0.00270891,"about_ca_system_score_codex":0.0007178874,"about_ca_system_score_gemma":0.00046913678,"threshold_uncertainty_score":0.0053203106},"labels":[],"label_agreement":null},{"id":"W4210539884","doi":"10.1172/jci152930","title":"Metronidazole treatment rapidly reduces genital inflammation through effects on bacterial vaginosis–associated bacteria rather than lactobacilli","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Global Health Research; Toronto General Hospital; University Health Network; University of Toronto","funders":"University of Toronto; National Institutes of Health; King's College London; Canadian Institutes of Health Research; National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network","keywords":"Lactobacillus crispatus; Bacterial vaginosis; Lactobacillus; Metronidazole; Gardnerella vaginalis; Immune system; Proinflammatory cytokine; Lactobacillus gasseri; Inflammation","score_opus":0.07097287300880298,"score_gpt":0.3653351124324978,"score_spread":0.29436223942369477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210539884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90700185,0.077211045,0.0013302374,0.0023800482,0.0011560621,0.004452677,0.0022114106,0.00017194377,0.004084697],"genre_scores_gemma":[0.971639,0.016587729,0.0024989876,0.0013448308,0.0005141302,0.00341699,0.00079457584,0.000025518482,0.003178185],"study_design_codex":"randomized_trial","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995709,0.00021514717,0.00004359045,0.000059536553,0.000043805154,0.00006692323],"domain_scores_gemma":[0.99954623,0.00013510915,0.00016737297,0.000026764536,0.00004461992,0.00007983757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008202716,0.0005097368,0.0014850907,0.00022972935,0.00019476336,0.0006894722,0.00046605794,0.00093753834,0.008236807],"category_scores_gemma":[0.0015607524,0.00026225683,0.00078778714,0.00025733156,0.00033660413,0.0004934744,0.00020153516,0.0012167136,0.0004261254],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.7298981,0.010594876,0.002955285,0.020265313,0.002647744,0.0001742555,0.0001361194,0.0005599656,0.051578913,0.00057488633,0.0063411007,0.17427346],"study_design_scores_gemma":[0.7522362,0.19958842,0.022763804,0.0019542486,0.002072159,0.00025316232,0.00014265213,0.000838809,0.009129433,0.000505045,0.010470156,0.000045929617],"about_ca_topic_score_codex":0.00052153063,"about_ca_topic_score_gemma":0.0015832311,"teacher_disagreement_score":0.008236807,"about_ca_system_score_codex":0.00040115567,"about_ca_system_score_gemma":0.0006640254,"threshold_uncertainty_score":0.02755481},"labels":[],"label_agreement":null},{"id":"W4210833716","doi":"10.1172/jci157124","title":"Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Economic and Social Research Council; School of Medicine, New York University; University College London; National Institute for Health Research Health Protection Research Unit; National Institute for Health and Care Research; York University; Wellcome Trust; University College London Hospitals NHS Foundation Trust; Pfizer","keywords":"Coinfection; Streptococcus pneumoniae; Immune system; Asymptomatic; Immunity; Acquired immune system; Cellular immunity; Respiratory system; Disease; Exacerbation","score_opus":0.09176330780616665,"score_gpt":0.3759521306607322,"score_spread":0.28418882285456554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210833716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99894696,0.00037149902,0.00006975888,0.00006428266,0.0000073164106,0.0000068150744,0.0000581013,0.000004167191,0.00047110507],"genre_scores_gemma":[0.99945265,0.00012377129,0.000083155326,0.000034344223,0.000023005585,0.000004470712,0.00012554342,0.000002054443,0.0001509288],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9994925,0.00019758813,0.000044298435,0.00008638402,0.0000766863,0.00010240751],"domain_scores_gemma":[0.9978296,0.0004126281,0.0011141426,0.00014351103,0.00015416072,0.0003460396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005431522,0.00041742317,0.00038583804,0.00043435962,0.00030047307,0.0006148606,0.00015590072,0.00043009126,0.0030586366],"category_scores_gemma":[0.0023229504,0.0002635844,0.00030030726,0.00037450972,0.0003254349,0.00020891038,0.0005135816,0.0005862452,0.0002798092],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013809331,0.00011498654,0.9898811,0.000039518713,0.0000706195,0.0004042392,0.00008158379,0.000043100343,0.0038997303,0.00003713852,0.00023331377,0.0038137515],"study_design_scores_gemma":[0.000019990237,0.00044634356,0.9975552,0.000010567854,0.000033410975,0.0010960822,0.00008008297,0.00013952874,0.0003274833,0.000051435694,0.00023673194,0.0000031862053],"about_ca_topic_score_codex":0.00074448285,"about_ca_topic_score_gemma":0.0009346303,"teacher_disagreement_score":0.0030586366,"about_ca_system_score_codex":0.00016229616,"about_ca_system_score_gemma":0.00033270384,"threshold_uncertainty_score":0.010232151},"labels":[],"label_agreement":null},{"id":"W4210905317","doi":"10.1172/jci154422","title":"The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Sydney Medical School Foundation; Sydney Medical School; amfAR, The Foundation for AIDS Research; Medical Research Council; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Australian Centre for HIV and Hepatitis Virology Research; Delaney AIDS Research Enterprise; University of Sydney","keywords":"Effector; Persistence (discontinuity); Memory T cell; Mutation; Memory cell; T cell; Virus","score_opus":0.05333448671185388,"score_gpt":0.3256872831512331,"score_spread":0.2723527964393792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210905317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99765164,0.00086887216,0.0008775967,0.000037666683,0.000003735729,0.00000893915,0.00009027998,0.000009614695,0.0004516436],"genre_scores_gemma":[0.99879056,0.00015494919,0.0005279266,0.000026992104,0.0000039600122,0.000008806106,0.00009983085,0.0000046754785,0.0003823814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992764,0.000012978389,0.0000041690273,0.000020271254,0.000013070791,0.00002183687],"domain_scores_gemma":[0.99991846,0.000023389599,0.000011808186,0.000011770601,0.000016026897,0.00001857639],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020152403,0.00012254866,0.00022761102,0.00022281645,0.00018984028,0.00035732612,0.00012346389,0.0002855381,0.001241257],"category_scores_gemma":[0.00034599888,0.00010392257,0.000118717755,0.00011733079,0.00019088596,0.0002941893,0.00016501604,0.00036261772,0.00014470845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009433531,0.00006950923,0.02941709,0.00007680751,0.000026421803,0.00017467687,0.00025467013,0.0002559518,0.95144963,0.0001286009,0.00008292977,0.017120343],"study_design_scores_gemma":[0.00006140292,0.0021477505,0.6823215,0.00006869047,0.00015504945,0.0035354476,0.0010348496,0.008610405,0.29543433,0.001847265,0.0047476655,0.000035635192],"about_ca_topic_score_codex":0.00044115575,"about_ca_topic_score_gemma":0.0006807658,"teacher_disagreement_score":0.001241257,"about_ca_system_score_codex":0.00012254281,"about_ca_system_score_gemma":0.000096219235,"threshold_uncertainty_score":0.004152477},"labels":[],"label_agreement":null},{"id":"W4212863820","doi":"10.1172/jci200315990","title":"Thyroid functions of mouse cathepsins B, K, and L","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Shriners Hospitals for Children; McGill University","keywords":"Thyroglobulin; Cathepsin; Cathepsin B; Proteolytic enzymes; Chemistry; Thyroid; Cathepsin D; Cathepsin H; Biochemistry; Molecular biology; Endocrinology; Internal medicine; Biology; Enzyme; Medicine","score_opus":0.0756598671017931,"score_gpt":0.3674383006342089,"score_spread":0.29177843353241584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212863820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99055934,0.0042414283,0.0023470372,0.00019176448,0.00002284929,0.000022757842,0.00060396787,0.000116807816,0.0018939566],"genre_scores_gemma":[0.9906358,0.0015747565,0.0017225866,0.000056517485,0.00001003639,0.00004354719,0.0010128854,0.000038276525,0.0049056066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997392,0.000034089422,0.000042637672,0.000057447534,0.000049723334,0.00007687799],"domain_scores_gemma":[0.9996381,0.000035277655,0.00012714491,0.00004598086,0.00004177448,0.00011164504],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025599153,0.00037883126,0.00019797776,0.0006546186,0.000258523,0.0005917329,0.00022455613,0.00038804187,0.001608452],"category_scores_gemma":[0.00022426964,0.00027497616,0.0004468441,0.00019378992,0.0003157715,0.00031402783,0.00023268795,0.00052260305,0.00048993394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005357301,0.000028786906,0.0007754877,0.000038079466,0.0000113944725,0.00007634644,0.00003233726,0.000040096387,0.99648654,0.00017300315,0.00005687845,0.0017453566],"study_design_scores_gemma":[0.000108085755,0.0004906172,0.011025982,0.000019815401,0.000086839405,0.0012589102,0.00009599228,0.000633132,0.98147315,0.00017067557,0.0046249228,0.000011913421],"about_ca_topic_score_codex":0.0015851213,"about_ca_topic_score_gemma":0.0013766689,"teacher_disagreement_score":0.001608452,"about_ca_system_score_codex":0.0008000775,"about_ca_system_score_gemma":0.00039037698,"threshold_uncertainty_score":0.005804956},"labels":[],"label_agreement":null},{"id":"W4213137283","doi":"10.1172/jci148667","title":"Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centro de Investigación Biomédica en Red de Cáncer; Sociedad Española de Oncología Médica; Ministerio de Ciencia e Innovación; Horizon 2020 Framework Programme; Eusko Jaurlaritza; Instituto de Salud Carlos III; Cancer Institute NSW; Department of Industry, Tourism and Trade; “la Caixa” Foundation; McGill University","keywords":"Oncostatin M; Tumor microenvironment; Stromal cell; Cancer research; Biology; Tumor progression; Cytokine; CXCL1; Reprogramming; Cancer cell; Cancer; Chemokine; Immune system; Immunology; Cell; Interleukin 6","score_opus":0.05346806453403087,"score_gpt":0.38561634642435566,"score_spread":0.3321482818903248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213137283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951479,0.0014022875,0.0010323665,0.00013409808,0.000035174664,0.000020011345,0.00022513428,0.00008293767,0.0019200862],"genre_scores_gemma":[0.9968988,0.00092470844,0.0009006048,0.0000513271,0.000013593014,0.000014584983,0.00017818919,0.000007326394,0.0010109325],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99992466,0.000016989079,0.000005714961,0.000008469378,0.000019684177,0.000024525594],"domain_scores_gemma":[0.999946,0.000008553735,0.000015617754,0.0000050508497,0.000005474328,0.000019277759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000077162076,0.00011988083,0.00011519912,0.00016068625,0.000067880785,0.00017615106,0.000042903113,0.00009899741,0.0010424197],"category_scores_gemma":[0.00007379373,0.000045760982,0.00010401199,0.000104165934,0.00011576314,0.000080702084,0.00012506782,0.00035412645,0.00018382893],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015162068,0.00003650422,0.00093935727,0.000034651435,0.0000035715045,0.00009137695,0.000011380436,0.000050265495,0.9948965,0.00007657172,0.00009907274,0.0036091772],"study_design_scores_gemma":[0.000048518737,0.00085854507,0.02837844,0.000012765996,0.00003203961,0.0009919059,0.00011941215,0.0013084441,0.95933914,0.00011458571,0.008791849,0.0000044417416],"about_ca_topic_score_codex":0.00020371852,"about_ca_topic_score_gemma":0.0005678434,"teacher_disagreement_score":0.0010424197,"about_ca_system_score_codex":0.00010505494,"about_ca_system_score_gemma":0.00016496803,"threshold_uncertainty_score":0.003487289},"labels":[],"label_agreement":null},{"id":"W4214883623","doi":"10.1172/jci152170","title":"USP25 inhibition ameliorates Alzheimer’s pathology through the regulation of APP processing and Aβ generation","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Xiamen University; Natural Science Foundation of Fujian Province; National Natural Science Foundation of China; Wenzhou Medical University","keywords":"Amyloid precursor protein; Pathogenesis; Deubiquitinating enzyme; Trisomy; Chromosome 21; Down syndrome; Regulator; Amyloid (mycology); Alzheimer's disease","score_opus":0.11537186688105582,"score_gpt":0.3596076202585578,"score_spread":0.24423575337750197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214883623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99570847,0.0020152184,0.000844521,0.00010459143,0.000040587485,0.00003272846,0.00025373156,0.000110857676,0.0008891102],"genre_scores_gemma":[0.99569535,0.0015480724,0.0008180354,0.000056617442,0.000015941501,0.000031550964,0.0003274422,0.000010262359,0.0014966031],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990976,0.000014847907,0.000016617485,0.000015703437,0.000019116485,0.000024005496],"domain_scores_gemma":[0.9999373,0.000006585081,0.000020334317,0.0000061693904,0.0000057445845,0.000023818908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013618846,0.00049730967,0.00030041122,0.0003801269,0.00014603543,0.00024479674,0.00021413017,0.00030392318,0.001007047],"category_scores_gemma":[0.00010119138,0.00012760662,0.000251792,0.00011700478,0.00028977823,0.00018646954,0.00014618672,0.00049412425,0.00017177533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072296744,0.00020269412,0.00018479074,0.00008388872,0.000018817618,0.000106910644,0.00001578411,0.000097009986,0.9939136,0.00016691603,0.00013657866,0.0043499405],"study_design_scores_gemma":[0.00019218457,0.0032171544,0.007527026,0.000017119655,0.0000690138,0.000428209,0.000044275566,0.0010707665,0.98282975,0.00015376115,0.004438553,0.0000122873425],"about_ca_topic_score_codex":0.0005911063,"about_ca_topic_score_gemma":0.0010271452,"teacher_disagreement_score":0.001007047,"about_ca_system_score_codex":0.00018475956,"about_ca_system_score_gemma":0.00025149446,"threshold_uncertainty_score":0.0033689141},"labels":[],"label_agreement":null},{"id":"W4220670650","doi":"10.1172/jci158468","title":"Training can’t always lead to Olympic macrophages","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; National Institutes of Health; Bill and Melinda Gates Foundation","keywords":"Transcriptome; Immune system; Innate immune system; Population; Immunity; Macrophage; Inflammation","score_opus":0.11694882780796106,"score_gpt":0.37871549457327536,"score_spread":0.2617666667653143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220670650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81442297,0.0258059,0.00742294,0.06905115,0.04781398,0.00032586046,0.001057194,0.00074497925,0.033355016],"genre_scores_gemma":[0.92843604,0.0068982374,0.0019804449,0.020286158,0.0048497985,0.00019992859,0.0004558063,0.00012053573,0.036773067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997656,0.0000381546,0.000013245566,0.000060093942,0.00003847395,0.00008449586],"domain_scores_gemma":[0.99966013,0.000047560272,0.000059277616,0.000035572455,0.000048815247,0.00014862126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003141431,0.00032493577,0.00032346055,0.00015929058,0.00043825965,0.00053339306,0.00029353373,0.0011537563,0.0064818365],"category_scores_gemma":[0.0007128752,0.0001700356,0.00040693465,0.000072387505,0.000562095,0.0002714741,0.0004370933,0.0017601672,0.001133101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0136317015,0.0032637506,0.028727835,0.0024174282,0.0008526946,0.0032566958,0.00071320694,0.0006503014,0.51201224,0.008653454,0.1547805,0.27104023],"study_design_scores_gemma":[0.0017034283,0.015361339,0.26694033,0.0014295693,0.0009784106,0.006921862,0.0031964711,0.002195003,0.2115747,0.017886266,0.47159266,0.00022004278],"about_ca_topic_score_codex":0.0003722189,"about_ca_topic_score_gemma":0.0009740911,"teacher_disagreement_score":0.0064818365,"about_ca_system_score_codex":0.00025160433,"about_ca_system_score_gemma":0.00023685354,"threshold_uncertainty_score":0.021683872},"labels":[],"label_agreement":null},{"id":"W4220752453","doi":"10.1172/jci156125","title":"Aerobic exercise elicits clinical adaptations in myotonic dystrophy type 1 patients independently of pathophysiological changes","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University Medical Centre; McMaster Children's Hospital; McMaster University","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Myotonic dystrophy; Cardiorespiratory fitness; Skeletal muscle; Disease; Clinical trial; Aerobic exercise; Muscular dystrophy; Exercise physiology; Duchenne muscular dystrophy; Neuromuscular disease","score_opus":0.15275745838125093,"score_gpt":0.38041484883668053,"score_spread":0.2276573904554296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220752453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957766,0.0017949035,0.00013773936,0.00015257165,0.000025580823,0.00018910036,0.00041746607,0.000016602096,0.0014894677],"genre_scores_gemma":[0.9970253,0.0005251627,0.0002719101,0.00019238499,0.000037684847,0.0002927752,0.0008605975,0.000003206956,0.00079097156],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997763,0.00008628733,0.000020792766,0.000048688267,0.000022921657,0.000045123215],"domain_scores_gemma":[0.99973613,0.000058205955,0.00008611065,0.000019271765,0.000019181532,0.000081040955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048486088,0.00028691208,0.0004365455,0.00019896199,0.00021783024,0.00026692438,0.00014447089,0.0003534531,0.003127287],"category_scores_gemma":[0.00048103556,0.000080401354,0.0002214639,0.00022686744,0.00020508902,0.00017441706,0.0003087802,0.00034042235,0.00024912658],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.2667127,0.010886408,0.34854665,0.0022412224,0.000846562,0.0010741885,0.00040757988,0.0007152315,0.07724428,0.00023562158,0.0038974532,0.28719217],"study_design_scores_gemma":[0.004927775,0.054555137,0.9314538,0.00032277402,0.00042983645,0.00110455,0.00023362761,0.0005918272,0.0035356118,0.00025232372,0.0025590463,0.000033610868],"about_ca_topic_score_codex":0.00031040004,"about_ca_topic_score_gemma":0.0008693244,"teacher_disagreement_score":0.003127287,"about_ca_system_score_codex":0.00020778143,"about_ca_system_score_gemma":0.00017102568,"threshold_uncertainty_score":0.010461807},"labels":[],"label_agreement":null},{"id":"W4220833681","doi":"10.1172/jci140685","title":"Macrophage-produced VEGFC is induced by efferocytosis to ameliorate cardiac injury and inflammation","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":157,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institutes of Health; American Heart Association; National Heart, Lung, and Blood Institute; Foundation for the National Institutes of Health","keywords":"Lymphangiogenesis; Efferocytosis; Vascular endothelial growth factor C; Proinflammatory cytokine; Inflammation; Endothelial dysfunction; Myeloid","score_opus":0.04245550277550015,"score_gpt":0.3334426956146183,"score_spread":0.29098719283911817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220833681","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861828,0.0059248568,0.0054735257,0.00030153827,0.00013964606,0.00013823937,0.0002913448,0.00017206762,0.0013760022],"genre_scores_gemma":[0.9921847,0.0013353231,0.003487705,0.00017234389,0.000043329503,0.0001044615,0.000322268,0.000042618092,0.0023074106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996784,0.000073177645,0.000034585795,0.00005333539,0.0000653444,0.00009522135],"domain_scores_gemma":[0.9998275,0.00001182494,0.000053521442,0.000016307635,0.000026105894,0.00006476471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042239812,0.00043843954,0.0006864667,0.00038044664,0.00015819212,0.00032826676,0.00020126403,0.00043113905,0.0010983585],"category_scores_gemma":[0.00018562091,0.00012535472,0.00025762813,0.00016535877,0.00037694248,0.00018709859,0.0002875833,0.0009431523,0.00030178222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034356027,0.00008667697,0.00012917872,0.00007437442,0.0000052695245,0.000033966502,0.000010582431,0.00004383352,0.99718374,0.00010687632,0.000055655757,0.0019263175],"study_design_scores_gemma":[0.0001683898,0.0015752956,0.004456341,0.000027945476,0.00004070753,0.00031213465,0.000034867444,0.0010432528,0.98740107,0.00012640616,0.0048060943,0.000007391973],"about_ca_topic_score_codex":0.00024247872,"about_ca_topic_score_gemma":0.00041659077,"teacher_disagreement_score":0.0010983585,"about_ca_system_score_codex":0.00024818844,"about_ca_system_score_gemma":0.00040277137,"threshold_uncertainty_score":0.003674388},"labels":[],"label_agreement":null},{"id":"W4220837317","doi":"10.1172/jci152187","title":"The Eph receptor A4 plays a role in demyelination and depression-related behavior","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Natural Science Foundation of China","keywords":"Erythropoietin-producing hepatocellular (Eph) receptor; Myelin; Ephrin; Gene knockdown; Receptor; Excitatory postsynaptic potential; Hippocampus","score_opus":0.08683182758100577,"score_gpt":0.3669623948683667,"score_spread":0.2801305672873609,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220837317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99294794,0.0040059052,0.0012945535,0.00020257717,0.000014595324,0.000016626516,0.00012976713,0.000020994048,0.00136707],"genre_scores_gemma":[0.9957754,0.0021405662,0.00057613873,0.000042545686,0.0000072676035,0.000014432281,0.00007645095,0.0000022480558,0.0013650528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994624,0.000016376498,0.0000053897043,0.000008588035,0.0000092428,0.000014086559],"domain_scores_gemma":[0.99993515,0.000005840581,0.000028318465,0.0000048026914,0.000008346992,0.000017434691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009150656,0.0002536681,0.00016005716,0.00016984763,0.00023266376,0.00021402893,0.00010715341,0.00025115733,0.0007451138],"category_scores_gemma":[0.0001296772,0.00010039413,0.00021412937,0.00008569113,0.00021986532,0.00013409421,0.00022284259,0.0002731841,0.00013434018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013943602,0.00015145593,0.012618693,0.00013719096,0.0000946322,0.00085562974,0.000052567633,0.00037247478,0.9690861,0.00069556164,0.00025677448,0.014284568],"study_design_scores_gemma":[0.00022261492,0.002740398,0.548115,0.00011202367,0.0003300072,0.005276335,0.0005450678,0.0058329618,0.4248299,0.002560881,0.009392925,0.000041848813],"about_ca_topic_score_codex":0.0012796998,"about_ca_topic_score_gemma":0.0014895344,"teacher_disagreement_score":0.0012796998,"about_ca_system_score_codex":0.000272541,"about_ca_system_score_gemma":0.00021660436,"threshold_uncertainty_score":0.0025445223},"labels":[],"label_agreement":null},{"id":"W4220994403","doi":"10.1172/jci140869","title":"Tankyrase represses autoinflammation through the attenuation of TLR2 signaling","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Hospital for Sick Children; SickKids Foundation; University Health Network; University of Toronto; Toronto Centre for Phenogenomics; Princess Margaret Cancer Centre","funders":"Japan Society for the Promotion of Science; Daiichi Sankyo Foundation of Life Science; Toray Science Foundation; Japan Intractable Diseases Research Foundation; Japan Foundation for Applied Enzymology","keywords":"Syk; TLR2; Phosphorylation; Inflammation; Signal transducing adaptor protein; Cell biology; Tyrosine phosphorylation; Signal transduction; Cancer research; Biology; Proto-oncogene tyrosine-protein kinase Src; TRIF; Cytokine; Innate immune system; Immunology; Tyrosine kinase; Toll-like receptor; TLR4; Immune system","score_opus":0.07134989035841112,"score_gpt":0.34908553086792554,"score_spread":0.27773564050951444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220994403","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927021,0.0026848875,0.0024802063,0.00031305657,0.00005023673,0.000028147482,0.0004260664,0.00018946275,0.0011257957],"genre_scores_gemma":[0.9953041,0.0007316412,0.0015186751,0.00006105525,0.000020289206,0.000025031568,0.00033413098,0.000018475435,0.00198652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983346,0.00004050157,0.000018447072,0.000028515742,0.000035524987,0.000043514086],"domain_scores_gemma":[0.9998554,0.00001879346,0.00005799314,0.00001596554,0.000011829184,0.000039983548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002028699,0.000338491,0.00026889553,0.00019977712,0.00011158327,0.00034896153,0.00023948561,0.00025629535,0.0019052168],"category_scores_gemma":[0.00016733588,0.00010765177,0.0001826405,0.00011781669,0.00028941847,0.00021786075,0.00021798938,0.0007610749,0.00040466466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020524436,0.0000355035,0.00009431742,0.000029082146,0.0000047347253,0.000033990553,0.0000068955114,0.0000376603,0.9985543,0.000050068724,0.000047667094,0.0009005085],"study_design_scores_gemma":[0.000106820255,0.000923835,0.0033640405,0.000008257418,0.000017851558,0.00036333143,0.000023083487,0.000747941,0.99163955,0.00008884251,0.002711149,0.0000052586947],"about_ca_topic_score_codex":0.00034574268,"about_ca_topic_score_gemma":0.0006549291,"teacher_disagreement_score":0.0019052168,"about_ca_system_score_codex":0.00024162109,"about_ca_system_score_gemma":0.0002591345,"threshold_uncertainty_score":0.0063735247},"labels":[],"label_agreement":null},{"id":"W4221001100","doi":"10.1172/jci151382","title":"NOGOB receptor deficiency increases cerebrovascular permeability and hemorrhage via impairing histone acetylation–mediated CCM1/2 expression","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Vascular Malformations Diagnosis and Treatment","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; Medical College of Wisconsin; School of Medicine, New York University; York University; American Heart Association","keywords":"Histone; Epigenetics; Acetylation; Histone acetyltransferase; Histone H4; Receptor; Pathogenesis; Histone H2A","score_opus":0.04399866428239658,"score_gpt":0.34313851592727296,"score_spread":0.2991398516448764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221001100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950643,0.0018853623,0.001598654,0.00011124057,0.000030957926,0.000015239353,0.00031353856,0.00010266547,0.00087798736],"genre_scores_gemma":[0.99520797,0.001260088,0.0013585252,0.00009337849,0.0000105177605,0.00002870115,0.00040489106,0.000022838842,0.0016129902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986506,0.00002054404,0.0000112217895,0.00003115645,0.000037063404,0.000034983197],"domain_scores_gemma":[0.9999201,0.0000068490986,0.000030299863,0.0000054001775,0.000005715971,0.000031643343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012918143,0.0003293194,0.0002869742,0.0002340269,0.0001371914,0.000228087,0.00015850211,0.0002522394,0.0010328089],"category_scores_gemma":[0.00012063951,0.00013714773,0.0002265674,0.000097145596,0.00030519994,0.00012630079,0.00016360068,0.0004050182,0.00015433747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001480702,0.000015215302,0.00026330794,0.000037857433,0.00000935811,0.0001177348,0.000009414783,0.00002729594,0.9985966,0.000055047738,0.000033354438,0.0006866529],"study_design_scores_gemma":[0.000053235406,0.0004914681,0.024159042,0.00001447833,0.000092150134,0.0010556923,0.00008443078,0.0011649054,0.96923614,0.00016319717,0.0034715747,0.000013581314],"about_ca_topic_score_codex":0.0009232633,"about_ca_topic_score_gemma":0.0019086157,"teacher_disagreement_score":0.0010328089,"about_ca_system_score_codex":0.0002030547,"about_ca_system_score_gemma":0.00024118241,"threshold_uncertainty_score":0.0034550428},"labels":[],"label_agreement":null},{"id":"W4221028282","doi":"10.1172/jci149571","title":"Gut-derived bacterial toxins impair memory CD4+ T cell mitochondrial function in HIV-1 infection","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; Center for AIDS Research, University of Washington; National Institutes of Health; Case Western Reserve University; National Institute on Aging; Eli Lilly and Company; Emory University; National Heart, Lung, and Blood Institute; Gilead Sciences","keywords":"T cell; Immune system; Cell; Cytotoxic T cell; CD8; Gut flora; Mitochondrion","score_opus":0.03318300433840342,"score_gpt":0.31931287941895337,"score_spread":0.28612987508054993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221028282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99924374,0.00043840043,0.00006850889,0.000020719157,0.000003757417,0.0000064109763,0.000043774697,0.0000052346377,0.00016943892],"genre_scores_gemma":[0.9990546,0.00025886105,0.00018628179,0.000034326124,0.000004488066,0.0000071428854,0.000083834886,0.0000020155007,0.0003683523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999199,0.000026823893,0.0000054685183,0.00001352047,0.000013188263,0.000021057127],"domain_scores_gemma":[0.9999229,0.000011844826,0.000020309199,0.0000052943446,0.000011441457,0.00002829744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015140747,0.00017840955,0.00016444523,0.00020141434,0.00016714372,0.00031921486,0.00011513422,0.00021844753,0.0012833397],"category_scores_gemma":[0.0002831422,0.00014863156,0.00009205382,0.00013327264,0.00014846101,0.00016085505,0.00024792025,0.00028411593,0.00010048406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004850232,0.0006494247,0.126499,0.00023321455,0.0000793154,0.00063646113,0.00038088282,0.00024957734,0.83372325,0.00009886554,0.00036072748,0.032239042],"study_design_scores_gemma":[0.00007857319,0.004431763,0.86282295,0.00004774458,0.00009249307,0.0016437137,0.00072627456,0.0014861602,0.1272413,0.00015230112,0.0012665867,0.0000101736705],"about_ca_topic_score_codex":0.0007704062,"about_ca_topic_score_gemma":0.0011209416,"teacher_disagreement_score":0.0012833397,"about_ca_system_score_codex":0.0001318618,"about_ca_system_score_gemma":0.00013103116,"threshold_uncertainty_score":0.0042932034},"labels":[],"label_agreement":null},{"id":"W4221035323","doi":"10.1172/jci158471","title":"The FoxOs are in the ApoM house","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Vanderbilt University Medical Center; Vanderbilt University","keywords":"Insulin resistance; Endocrinology; Internal medicine; Metabolic syndrome; Apolipoprotein B; Biology; Lipid metabolism; Insulin; Diabetes mellitus; Medicine; Cholesterol","score_opus":0.08489197724774487,"score_gpt":0.347899911081844,"score_spread":0.2630079338340991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221035323","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022869364,0.013470393,0.00048285056,0.87159765,0.10362359,0.000021549204,0.000083991144,0.00014940278,0.008283663],"genre_scores_gemma":[0.038435236,0.024528664,0.0014700771,0.6914364,0.18620266,0.0000808741,0.0001459845,0.00008976978,0.05761035],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99932384,0.00012278464,0.000057885194,0.0001231403,0.00028678283,0.0000855571],"domain_scores_gemma":[0.9988036,0.0004224544,0.000114801835,0.00011337435,0.00023791144,0.00030791844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009963253,0.00055656687,0.0005211875,0.0002936395,0.0013525661,0.0013247132,0.00051632174,0.006628862,0.00690578],"category_scores_gemma":[0.0044279937,0.00023481857,0.0005728673,0.00017453685,0.0020211893,0.0016533037,0.00086820725,0.010036409,0.0043963837],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034117984,0.00008690304,0.0012722864,0.00013792538,0.000032425884,0.0027443238,0.00018553218,0.000055180597,0.0033487943,0.006738857,0.9169623,0.068094365],"study_design_scores_gemma":[0.00009042415,0.00008366218,0.0011205924,0.000091182046,0.000016940006,0.0020289896,0.00016889429,0.00009283726,0.0007674173,0.0056138146,0.989906,0.000019241566],"about_ca_topic_score_codex":0.0011576363,"about_ca_topic_score_gemma":0.001852747,"teacher_disagreement_score":0.00690578,"about_ca_system_score_codex":0.0011370828,"about_ca_system_score_gemma":0.0010726813,"threshold_uncertainty_score":0.023102164},"labels":[],"label_agreement":null},{"id":"W4223914468","doi":"10.1172/jci160227","title":"Recalibrating vascular malformations and mechanotransduction by pharmacological intervention","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Vascular Malformations and Hemangiomas","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Fondation Leducq","keywords":"Mechanotransduction; Blood flow; Blood vessel; Hemodynamics; Endothelium; Arteriogenesis; Lymphatic system; Endothelial stem cell","score_opus":0.0721099845487768,"score_gpt":0.3786889344411071,"score_spread":0.30657894989233025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223914468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7376489,0.15473649,0.04254187,0.008794224,0.0027896632,0.0013003832,0.00049680396,0.001332535,0.05035905],"genre_scores_gemma":[0.92014354,0.06000001,0.010960819,0.0017515549,0.00061299937,0.00047650377,0.00022030399,0.00004591234,0.0057884445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998902,0.000031894037,0.000010068364,0.000014306947,0.000023624661,0.000029983858],"domain_scores_gemma":[0.9999293,0.00001847398,0.000020389654,0.000008171148,0.000008523195,0.000015080555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000256353,0.00034450815,0.0003187769,0.00042172807,0.00021037055,0.00038447347,0.0002740954,0.00037053437,0.0022266707],"category_scores_gemma":[0.00030154956,0.00008752486,0.0002780991,0.0001840462,0.00051442505,0.00025644322,0.0002603815,0.0011411993,0.00033802097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030113265,0.0031665212,0.0015358686,0.0025661802,0.00019015966,0.0020055177,0.00015147308,0.0006816409,0.5850054,0.01283855,0.0072687147,0.38157865],"study_design_scores_gemma":[0.002834917,0.020011807,0.032462284,0.0015736237,0.00057163957,0.013340026,0.00051481236,0.0055046524,0.6402113,0.012876847,0.2699853,0.00011281774],"about_ca_topic_score_codex":0.00021409891,"about_ca_topic_score_gemma":0.00051322655,"teacher_disagreement_score":0.0022266707,"about_ca_system_score_codex":0.00017701178,"about_ca_system_score_gemma":0.00033796125,"threshold_uncertainty_score":0.0074489713},"labels":[],"label_agreement":null},{"id":"W4223954793","doi":"10.1172/jci151817","title":"Long-term male-specific chronic pain via telomere- and p53‑mediated spinal cord cellular senescence","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Medical Research Council; Canadian Institutes of Health Research; Louise and Alan Edwards Foundation; Cancer Council NSW; Fondation Brain Canada; McGill University","keywords":"Spinal cord; Chronic pain; Medicine; Microglia; Senescence; Neuropathic pain; Telomere; Nerve injury; Spinal cord injury; Nociception; Neuroscience; Bioinformatics; Biology; Internal medicine; Anesthesia; Inflammation; Genetics; Receptor; Gene","score_opus":0.08039352377105839,"score_gpt":0.3572583771842888,"score_spread":0.2768648534132304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223954793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916613,0.0030795601,0.0033047947,0.00017118508,0.00004601719,0.000026262047,0.00053450436,0.00007635177,0.0010999485],"genre_scores_gemma":[0.99553406,0.0013768004,0.0006093297,0.00006600552,0.000019956986,0.00003352407,0.0003411852,0.000008586537,0.0020106533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998553,0.000023936751,0.000012175698,0.000040993407,0.000031610554,0.00003607716],"domain_scores_gemma":[0.99976856,0.000016022095,0.00013971474,0.000025856585,0.000016857035,0.000033053297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002258675,0.00031730332,0.00019137783,0.00041956388,0.00013181113,0.0002435768,0.00013992678,0.00021401177,0.0019599558],"category_scores_gemma":[0.0001742108,0.00010171098,0.00028015327,0.00014892338,0.00026439686,0.00023466146,0.00020764854,0.00045678462,0.00025414405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044697546,0.000069416004,0.0020728002,0.000050957628,0.000016299653,0.00015876032,0.000046148427,0.000034226636,0.99141747,0.00020598984,0.0000656854,0.0054152757],"study_design_scores_gemma":[0.00006730487,0.0051063504,0.14845234,0.000058558468,0.000092073664,0.0025747365,0.00018647613,0.0006612861,0.83765954,0.00042858883,0.004691249,0.000021516033],"about_ca_topic_score_codex":0.00017617442,"about_ca_topic_score_gemma":0.00042781615,"teacher_disagreement_score":0.0019599558,"about_ca_system_score_codex":0.00012143091,"about_ca_system_score_gemma":0.0001642398,"threshold_uncertainty_score":0.0065566897},"labels":[],"label_agreement":null},{"id":"W4225255751","doi":"10.1172/jci157011","title":"Through the layers: how macrophages drive atherosclerosis across the vessel wall","year":2022,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; European Research Area Network on Cardiovascular Diseases","keywords":"Arterial wall; Extracellular matrix; Disease; Macrophage; Coronary artery disease; Inflammation; Cholesterol; Medicine; Smooth muscle; Monocyte; Endothelium; Function (biology); Immunology; Pathology; Biology; Cardiology; Cell biology; Internal medicine; Genetics","score_opus":0.1920626887045189,"score_gpt":0.4241103451371271,"score_spread":0.2320476564326082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225255751","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015895761,0.9966364,0.00024715322,0.00088603905,0.00079690036,0.0000065986646,0.00001681365,0.0000135541795,0.001237481],"genre_scores_gemma":[0.001088611,0.99616265,0.00025272288,0.0006207873,0.00043749338,0.0000089772175,0.000024173205,0.0000029545,0.001401626],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998197,0.00003533993,0.000019291912,0.00002907549,0.00007250287,0.000024165514],"domain_scores_gemma":[0.9998281,0.000055770255,0.000017003305,0.0000064961678,0.00006468321,0.000027877031],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005504636,0.0006436985,0.0008750632,0.0011405922,0.00030348395,0.0011743915,0.0007322908,0.0012744792,0.0026211953],"category_scores_gemma":[0.00053340447,0.0002240247,0.0003536678,0.0007211452,0.0006196455,0.0015357805,0.0007422051,0.0022209436,0.0026700764],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000113369984,0.00005067334,0.00022655183,0.009451217,0.00005462279,0.00020863072,0.0001318693,0.00027874962,0.0058943834,0.011620458,0.05653853,0.9154309],"study_design_scores_gemma":[0.000011588598,0.00007837122,0.00035400206,0.0014162924,0.00002802242,0.00059411477,0.000052114116,0.00005298965,0.00076875294,0.002642591,0.9939902,0.000010872049],"about_ca_topic_score_codex":0.0006305928,"about_ca_topic_score_gemma":0.0011186039,"teacher_disagreement_score":0.0026211953,"about_ca_system_score_codex":0.0005893568,"about_ca_system_score_gemma":0.0008554942,"threshold_uncertainty_score":0.008768797},"labels":[],"label_agreement":null},{"id":"W4225939416","doi":"10.1172/jci154891","title":"Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"National Health and Medical Research Council; National Institute of General Medical Sciences; Medical Research Council; Canadian Institutes of Health Research; Loxo Oncology; National Institutes of Health; Weill Cornell Medical College; McGill University; University of Sydney; National Centre for Supercomputing Applications; Eli Lilly and Company","keywords":"Glutamate receptor; Chloride channel; Ataxia; Neurotoxicity; Excitatory postsynaptic potential; Biology; Cell biology; Mutation; Neuroscience; Chemistry; Biochemistry; Inhibitory postsynaptic potential; Receptor","score_opus":0.20338422515562962,"score_gpt":0.4276291718869455,"score_spread":0.22424494673131587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225939416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997712,0.0004217537,0.0007033517,0.00008323206,0.000017775954,0.000011566923,0.00036948553,0.00004781689,0.00063312246],"genre_scores_gemma":[0.9985281,0.00022579324,0.0004933408,0.000049399896,0.000004655449,0.000005408327,0.0001843108,0.000019771616,0.00048923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998956,0.000016991275,0.00001819091,0.000023166738,0.000027513177,0.000018444065],"domain_scores_gemma":[0.99990296,0.000019785815,0.000030748153,0.0000061054925,0.000011823104,0.000028533776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009039419,0.00044775207,0.00024180017,0.00020441256,0.00019854223,0.00017935825,0.00015560414,0.0005447782,0.0017281126],"category_scores_gemma":[0.0002020566,0.000070385366,0.0003315238,0.00019728827,0.0003312199,0.000144128,0.00017186775,0.00032909057,0.00025961478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017188989,0.000026776785,0.0014326903,0.000026096654,0.000014385439,0.0014872801,0.00003822893,0.00014208388,0.99529606,0.00010167263,0.000064076565,0.0011987735],"study_design_scores_gemma":[0.000093619004,0.00079683913,0.09490321,0.000031865085,0.00013652905,0.01530644,0.00017594239,0.0032792953,0.87960523,0.00034671737,0.005287865,0.00003639395],"about_ca_topic_score_codex":0.0029106059,"about_ca_topic_score_gemma":0.0037965758,"teacher_disagreement_score":0.0029106059,"about_ca_system_score_codex":0.00035770715,"about_ca_system_score_gemma":0.00023681513,"threshold_uncertainty_score":0.0057873726},"labels":[],"label_agreement":null},{"id":"W4226281599","doi":"10.1172/jci145343","title":"Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Terry Fox Research Institute; University of British Columbia; Spinal Cord Injury BC","funders":"Weill Cornell Medical College; National Cancer Institute; BC Cancer Foundation; Terry Fox Research Institute; Genome British Columbia; Michael Smith Health Research BC; Leukemia and Lymphoma Society of Canada; Canadian Institutes of Health Research; Genome Canada; Uehara Memorial Foundation; Leukemia and Lymphoma Society","keywords":"Diffuse large B-cell lymphoma; EZH2; Lymphoma; Tumor microenvironment; Epigenetics; Immune system; Somatic cell; Antigen; Reprogramming","score_opus":0.048893662792145666,"score_gpt":0.30494434180959645,"score_spread":0.25605067901745077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226281599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99593395,0.0015624078,0.0014093448,0.000054726308,0.000009296602,0.0000062084896,0.000106345804,0.000045745517,0.00087218476],"genre_scores_gemma":[0.9984444,0.00023156192,0.00031044826,0.000021897127,0.000003560624,0.000005675164,0.00013388463,0.0000048510137,0.000843725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999912,0.00001599488,0.00000426956,0.000020730937,0.000019746616,0.000027202863],"domain_scores_gemma":[0.99994826,0.0000074918325,0.000013968769,0.000008309422,0.000004059352,0.000017985825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008972587,0.00017114918,0.00015852129,0.00015563412,0.00008020387,0.00018238435,0.000106521264,0.00019683507,0.0012110509],"category_scores_gemma":[0.00008971441,0.000089613255,0.00013095349,0.00009364038,0.00016188133,0.00016823612,0.00020270575,0.00037308043,0.00029458504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008830493,0.000009624436,0.0004557494,0.000013409297,0.0000032962248,0.00005213769,0.0000042419606,0.00002424956,0.99813485,0.000064680484,0.000020601503,0.0011288327],"study_design_scores_gemma":[0.00003544443,0.0006575221,0.035240967,0.0000038230473,0.000035473484,0.002317801,0.000044186803,0.0011934472,0.9558698,0.0001480296,0.0044472907,0.000006216496],"about_ca_topic_score_codex":0.00008455312,"about_ca_topic_score_gemma":0.00021342289,"teacher_disagreement_score":0.0012110509,"about_ca_system_score_codex":0.00012965196,"about_ca_system_score_gemma":0.000060024515,"threshold_uncertainty_score":0.0040513277},"labels":[],"label_agreement":null},{"id":"W4229012234","doi":"10.1172/jci152565","title":"Peripheral monocyte–derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Hope Center for Neurological Disorders; National Institutes of Health; National Institute of Neurological Disorders and Stroke; Alzheimer's Association","keywords":"Choroid plexus; Microglia; Parenchyma; Pathology; Monocyte; Haematopoiesis; Pathogenesis; Senile plaques; Biology; Macrophage; Amyloid (mycology); Immunology; Alzheimer's disease; Medicine; Disease; Central nervous system; Inflammation; Cell biology; Neuroscience; Stem cell","score_opus":0.15232280349401342,"score_gpt":0.3436018812800069,"score_spread":0.19127907778599348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229012234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931538,0.0021966223,0.0015424351,0.00033986944,0.00019490135,0.00009592517,0.00033002265,0.00020950283,0.0019368632],"genre_scores_gemma":[0.98535156,0.0019100544,0.0037959474,0.00026987365,0.00011218434,0.00027485364,0.00047353236,0.000048369762,0.007763731],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996222,0.000076236465,0.000044467914,0.00006237246,0.00008117753,0.000113556154],"domain_scores_gemma":[0.99970466,0.000022775072,0.000053654425,0.000041631298,0.0000517774,0.00012560238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005062273,0.00075116643,0.0010226726,0.00074297644,0.00034132562,0.0006487627,0.0003151342,0.0007433532,0.0015857114],"category_scores_gemma":[0.00023033886,0.000348211,0.0002442007,0.0002771552,0.00049804,0.00038825406,0.0002894499,0.002243282,0.0006453638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018689915,0.0008809302,0.00032810893,0.00010980938,0.000021125485,0.00010836437,0.00011281801,0.0001280576,0.9907783,0.00027077238,0.00026862984,0.005123963],"study_design_scores_gemma":[0.000739755,0.007254303,0.0066053006,0.00008459865,0.00013424705,0.0005624688,0.00015750069,0.0030535636,0.97209543,0.00047941113,0.008803616,0.00002984655],"about_ca_topic_score_codex":0.00071423664,"about_ca_topic_score_gemma":0.0013554604,"teacher_disagreement_score":0.0015857114,"about_ca_system_score_codex":0.00031306976,"about_ca_system_score_gemma":0.0005061274,"threshold_uncertainty_score":0.005304754},"labels":[],"label_agreement":null},{"id":"W4229563830","doi":"10.1172/jci0215952","title":"The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":252,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada; Montreal Children's Hospital","funders":"","keywords":"Osteogenesis imperfecta; Cancellous bone; Resorption; Cortical bone; Bone remodeling; Bone resorption; Medicine; Biopsy; Endocrinology; Bone histomorphometry; Bone biopsy; Internal medicine; Osteoporosis; Anatomy; Trabecular bone","score_opus":0.020012068377054014,"score_gpt":0.3061488085369086,"score_spread":0.28613674015985463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229563830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99957305,0.00028944074,0.000030262265,0.000013251808,0.0000010544571,0.0000024166961,0.000017458888,0.0000020857995,0.000071023576],"genre_scores_gemma":[0.9994325,0.00023793097,0.00017673064,0.000019050829,0.000004947371,0.000006761043,0.000055591358,0.0000015755534,0.000064775566],"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.99978155,0.00008586657,0.000016418804,0.000025889296,0.000044600212,0.00004565091],"domain_scores_gemma":[0.99961805,0.00013506268,0.00015377172,0.000014936615,0.000015081297,0.00006309154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002566416,0.00021864945,0.0002974155,0.00025369567,0.00017682555,0.0001690335,0.0001294332,0.0002653884,0.0002872509],"category_scores_gemma":[0.0011082856,0.00018670529,0.0002064404,0.00016544489,0.00044001386,0.00013179945,0.00015695977,0.00032959168,0.00007848143],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008446092,0.00075550005,0.84248024,0.00025785298,0.00015720098,0.0060846666,0.000806973,0.00063189265,0.08173334,0.00009612996,0.00029235045,0.058257718],"study_design_scores_gemma":[0.00017288819,0.008572922,0.9741253,0.000014457634,0.00009884769,0.0075345626,0.0002675524,0.00033231796,0.008113886,0.00004305461,0.00071490806,0.000009395318],"about_ca_topic_score_codex":0.0010933726,"about_ca_topic_score_gemma":0.0018333625,"teacher_disagreement_score":0.0010933726,"about_ca_system_score_codex":0.00025280085,"about_ca_system_score_gemma":0.00017943521,"threshold_uncertainty_score":0.0021740198},"labels":[],"label_agreement":null},{"id":"W4229840448","doi":"10.1172/jci200216551","title":"Hot new therapy for sepsis and the acute respiratory distress syndrome","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Sepsis; Acute respiratory distress; Medicine; Intensive care medicine; Respiratory distress; Internal medicine; Lung; Surgery","score_opus":0.1638049174077532,"score_gpt":0.3966959609612309,"score_spread":0.2328910435534777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229840448","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011306736,0.90676206,0.001775925,0.039832447,0.013165086,0.00007220365,0.00006673557,0.0000882508,0.026930632],"genre_scores_gemma":[0.11248998,0.7369099,0.003949937,0.05057922,0.035313755,0.00024022737,0.00020259329,0.00004587908,0.060268573],"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.9997533,0.000089145055,0.000014890503,0.000024482533,0.000084256724,0.00003390322],"domain_scores_gemma":[0.9998091,0.00008158521,0.000037792728,0.000008616109,0.00002334359,0.000039632665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005343548,0.00035780077,0.00046769012,0.00054879615,0.00036939397,0.0005092698,0.00027801824,0.0009587447,0.007224948],"category_scores_gemma":[0.0004689423,0.00008566548,0.0002469111,0.00026355323,0.0006148539,0.00082052854,0.00059461594,0.0013063349,0.0013928019],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013578866,0.0003896145,0.0013094372,0.0020189201,0.0001153661,0.0019200061,0.00032135413,0.00019941118,0.018681398,0.026086489,0.11296555,0.8346346],"study_design_scores_gemma":[0.00034692104,0.0012113174,0.0044200257,0.0005564867,0.000076656135,0.003572172,0.0001388078,0.00024180266,0.0029420927,0.0078176325,0.9786526,0.000023422608],"about_ca_topic_score_codex":0.00013167533,"about_ca_topic_score_gemma":0.00056641066,"teacher_disagreement_score":0.007224948,"about_ca_system_score_codex":0.0002782585,"about_ca_system_score_gemma":0.00032270097,"threshold_uncertainty_score":0.024169862},"labels":[],"label_agreement":null},{"id":"W4230835938","doi":"10.1172/jci200317974","title":"Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Christie (Canada)","funders":"Wellcome Trust; GlaxoSmithKline","keywords":"Basement membrane; Asthma; Medicine; Membrane; Pathology; Chemistry; Immunology; Biochemistry","score_opus":0.06907356681266541,"score_gpt":0.36392874154126686,"score_spread":0.29485517472860145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230835938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99741447,0.0021682507,0.00013319933,0.000058281057,0.000026833726,0.000035252728,0.000026664342,0.000016710164,0.00012019782],"genre_scores_gemma":[0.99828315,0.0007700413,0.00027495113,0.00011680586,0.000049345967,0.00004760709,0.00007622879,0.0000027240194,0.00037914782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997893,0.00006830309,0.00002351966,0.00002570052,0.000044474626,0.000048796137],"domain_scores_gemma":[0.99973434,0.000047818638,0.00007780919,0.000013681325,0.000021533764,0.00010480711],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035132858,0.00039429756,0.001212634,0.00019831973,0.00024840102,0.000281775,0.0002566778,0.00046314936,0.0008927479],"category_scores_gemma":[0.00039678073,0.00021499574,0.0003077114,0.00008042789,0.00025669616,0.00020158167,0.00014835644,0.0008013681,0.00015721904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06841872,0.0071959496,0.01360273,0.00063506153,0.00036115712,0.0005068466,0.00016020221,0.00029309088,0.83743876,0.000056295823,0.00040533772,0.07092585],"study_design_scores_gemma":[0.01757169,0.3020492,0.5097213,0.0001174649,0.0013155456,0.0015519637,0.0002974625,0.0018814505,0.16008686,0.00014735154,0.0052120835,0.000047779777],"about_ca_topic_score_codex":0.00040369813,"about_ca_topic_score_gemma":0.0008990754,"teacher_disagreement_score":0.001212634,"about_ca_system_score_codex":0.00018620979,"about_ca_system_score_gemma":0.00015484454,"threshold_uncertainty_score":0.0029865503},"labels":[],"label_agreement":null},{"id":"W4231058232","doi":"10.1172/jci200213265","title":"Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; St. Michael's Hospital; Toronto General Hospital; Heart and Stroke Foundation; University of Toronto","funders":"Medical Research Council; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Peroxynitrite; Block (permutation group theory); Chemistry; Heart block; Cardiology; Internal medicine; Medicine; Cell biology; Biology; Biochemistry; Electrocardiography; Superoxide; Enzyme","score_opus":0.11609978838374604,"score_gpt":0.36468479715062524,"score_spread":0.2485850087668792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231058232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956856,0.00058048463,0.002472087,0.00011615446,0.000032695796,0.000039085793,0.00016792299,0.00013848185,0.0007676569],"genre_scores_gemma":[0.99297124,0.00077852607,0.0029976266,0.00012203215,0.00002647659,0.000084453946,0.00037751126,0.000057400834,0.002584812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996873,0.000073322626,0.000043246782,0.000055516673,0.000058162273,0.00008240143],"domain_scores_gemma":[0.9996101,0.00006620086,0.00013526477,0.000034374574,0.000019311243,0.00013481145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044642197,0.0005733881,0.0003604314,0.0003248413,0.00021457797,0.0002585733,0.00016972604,0.0004755648,0.001289445],"category_scores_gemma":[0.0002583998,0.000331723,0.0002061424,0.00014809948,0.0005183084,0.00027486397,0.00020972246,0.000851087,0.00042256448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038660015,0.0001376176,0.0004049611,0.000028592347,0.000006514909,0.0001978917,0.000021003185,0.000045595287,0.99741745,0.00012739326,0.000042637836,0.0011837351],"study_design_scores_gemma":[0.00043553722,0.0054660756,0.013449303,0.0000388877,0.00007521436,0.0029637944,0.000091706126,0.0016537814,0.97328883,0.00023713916,0.0022837769,0.000016031925],"about_ca_topic_score_codex":0.00010588921,"about_ca_topic_score_gemma":0.00028198538,"teacher_disagreement_score":0.001289445,"about_ca_system_score_codex":0.00017494973,"about_ca_system_score_gemma":0.00016120604,"threshold_uncertainty_score":0.0043136477},"labels":[],"label_agreement":null},{"id":"W4231840887","doi":"10.1172/jci200213946","title":"Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institutes of Health; American Diabetes Association","keywords":"GLUT4; Internal medicine; Endocrinology; Insulin receptor; Insulin; Biology; Glucose uptake; GLUT1; Glucose transporter; Carbohydrate metabolism; Glycolysis; Metabolism; Insulin resistance; Medicine","score_opus":0.053149278519857374,"score_gpt":0.31416502144666303,"score_spread":0.2610157429268056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231840887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907986,0.0019883113,0.0048509417,0.000094282244,0.000022430931,0.000013032987,0.00020788683,0.0000820851,0.0019423097],"genre_scores_gemma":[0.991089,0.0016730941,0.0045621987,0.000061572144,0.00002342529,0.000039672086,0.00044420653,0.000043781987,0.0020630963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999019,0.000011521861,0.000008243795,0.000032118638,0.000026502641,0.000019736399],"domain_scores_gemma":[0.99985874,0.000018756942,0.000051216924,0.0000158626,0.000020367517,0.000035041077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013869801,0.00025517982,0.00023479776,0.00021950503,0.00009013923,0.00032907113,0.00018145495,0.00015047369,0.0006772633],"category_scores_gemma":[0.00014921975,0.00017402403,0.00012309937,0.00014631405,0.00017212228,0.00024297116,0.00018764065,0.0004068579,0.00014361205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011908843,0.000010610663,0.0012504098,0.000012696224,0.0000022650383,0.00006915228,0.000010402943,0.000032884425,0.9957066,0.00009732246,0.000031704272,0.0026569166],"study_design_scores_gemma":[0.00006700555,0.00051107,0.16499151,0.000017130395,0.000059824768,0.001186955,0.00009372383,0.0014873404,0.8279624,0.0004138532,0.0031951566,0.000013963271],"about_ca_topic_score_codex":0.00018688783,"about_ca_topic_score_gemma":0.00036542641,"teacher_disagreement_score":0.0006772633,"about_ca_system_score_codex":0.00022162104,"about_ca_system_score_gemma":0.0000932854,"threshold_uncertainty_score":0.0022656322},"labels":[],"label_agreement":null},{"id":"W4231969407","doi":"10.1172/jci0215883","title":"EphB6 crosslinking results in costimulation of T cells","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Roche Organ Transplant Research Foundation; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"CD28; Biology; T cell; T-cell receptor; Cell biology; Molecular biology; Immunology; Immune system","score_opus":0.27908655831452694,"score_gpt":0.4060633871174051,"score_spread":0.12697682880287814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231969407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99135953,0.0020267123,0.0017829558,0.00016854602,0.00013429577,0.000066318855,0.0004066719,0.000098507706,0.003956515],"genre_scores_gemma":[0.9889537,0.0009992507,0.0027282885,0.00015594772,0.00006215103,0.0001106143,0.0008594357,0.000039703064,0.0060908603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955374,0.00007672113,0.000039167797,0.00008514086,0.00009592392,0.0001492951],"domain_scores_gemma":[0.9998271,0.000042688538,0.000023804136,0.000022139722,0.000013252813,0.0000710875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001510176,0.0006740035,0.00032478187,0.00018845951,0.00013644465,0.00027954974,0.0001995597,0.0004249482,0.0032514974],"category_scores_gemma":[0.00014481046,0.00017497291,0.0002870754,0.00015782195,0.00011683553,0.00022662293,0.00037516293,0.0011238498,0.0011806559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022682814,0.00006966888,0.00006307073,0.00004564023,0.0000072814,0.00008656956,0.000015856562,0.000057041743,0.9980293,0.000101261525,0.00010036988,0.0011970571],"study_design_scores_gemma":[0.000042900636,0.0004029133,0.002375949,0.000008602872,0.000021693224,0.00047001572,0.000011672757,0.00077547383,0.9916425,0.00004694275,0.0041975165,0.0000037493953],"about_ca_topic_score_codex":0.0002282678,"about_ca_topic_score_gemma":0.000360523,"teacher_disagreement_score":0.0032514974,"about_ca_system_score_codex":0.00026900656,"about_ca_system_score_gemma":0.00016423335,"threshold_uncertainty_score":0.010877311},"labels":[],"label_agreement":null},{"id":"W4232216688","doi":"10.1172/jci200522365","title":"The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of Pennsylvania","keywords":"Endocrinology; Internal medicine; Biology; Glucose homeostasis; Hyperinsulinemia; Insulin; Hepatocyte nuclear factors; Potassium channel; Beta cell; Conditional gene knockout; Maturity onset diabetes of the young; Phenotype; Gene; Cell biology; Islet; Gene expression; Diabetes mellitus; Type 2 diabetes; Genetics; Insulin resistance; Medicine","score_opus":0.06396157975609104,"score_gpt":0.3416323734573163,"score_spread":0.27767079370122527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4232216688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940686,0.0012151256,0.0030919341,0.00006919732,0.000027973923,0.00001682284,0.0003760132,0.00008048269,0.0010537931],"genre_scores_gemma":[0.9929658,0.0008844587,0.002498199,0.000049766863,0.000011803926,0.000021924658,0.0005704853,0.00004401038,0.0029535454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999174,0.000009264065,0.0000055243977,0.000021430265,0.00002168536,0.000024725434],"domain_scores_gemma":[0.9999056,0.000013170629,0.000040213396,0.000008505495,0.000009590733,0.000023064329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011756082,0.0003736761,0.0002141608,0.00026935225,0.00015716553,0.00019322848,0.0001631444,0.00013864962,0.0008653706],"category_scores_gemma":[0.00012039737,0.00012037132,0.00016555787,0.00010596902,0.00026283154,0.00011602196,0.00022925541,0.00030411824,0.0002907629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019847025,0.000015307667,0.002229383,0.000020069747,0.000004018676,0.00022615338,0.000019269657,0.00008935515,0.994221,0.00014544414,0.000059536083,0.0027719613],"study_design_scores_gemma":[0.00004710854,0.00018230497,0.0354381,0.000014190244,0.000021656571,0.0012630281,0.00006814455,0.0014851392,0.9554582,0.00019027502,0.005823379,0.0000084411995],"about_ca_topic_score_codex":0.0005200593,"about_ca_topic_score_gemma":0.00078491686,"teacher_disagreement_score":0.0008653706,"about_ca_system_score_codex":0.00046721046,"about_ca_system_score_gemma":0.00019573403,"threshold_uncertainty_score":0.003389895},"labels":[],"label_agreement":null},{"id":"W4233129017","doi":"10.1172/jci200318359","title":"Coordinated tumor immunity","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Leukemia and Lymphoma Society; National Institutes of Health; Cancer Research Institute","keywords":"Immunity; Medicine; Immunology; Biology; Immune system","score_opus":0.06251970864299455,"score_gpt":0.3512548705233633,"score_spread":0.28873516188036874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233129017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6437192,0.064709626,0.057478357,0.012457869,0.00912684,0.0013282995,0.00232519,0.0036624428,0.20519222],"genre_scores_gemma":[0.94646776,0.0050686765,0.006420791,0.0014254843,0.0013160775,0.00038304858,0.00090856594,0.0001205732,0.037889045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989748,0.00019653604,0.000041414223,0.00028228352,0.00024575088,0.00025922107],"domain_scores_gemma":[0.9993223,0.00005205699,0.00010473945,0.00013275277,0.00014227213,0.0002459004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007569243,0.00066888594,0.00063967105,0.0008721543,0.00048953295,0.0019500017,0.00046457982,0.0005799214,0.011052681],"category_scores_gemma":[0.00079359184,0.00032222047,0.00039964396,0.00026116942,0.00039260447,0.0007397686,0.0019610827,0.0020306122,0.003620163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013707172,0.0005070894,0.00794001,0.00073260133,0.00015980522,0.0007342748,0.00037649146,0.0009221743,0.69708097,0.033587515,0.03951325,0.21707514],"study_design_scores_gemma":[0.0006896208,0.0040155677,0.053692847,0.00044483037,0.00050130754,0.0048331073,0.0009454894,0.0072063655,0.287451,0.03061386,0.60951823,0.00008779529],"about_ca_topic_score_codex":0.00016031163,"about_ca_topic_score_gemma":0.00030237925,"teacher_disagreement_score":0.011052681,"about_ca_system_score_codex":0.00094481395,"about_ca_system_score_gemma":0.0009795723,"threshold_uncertainty_score":0.036974847},"labels":[],"label_agreement":null},{"id":"W4233455462","doi":"10.1172/jci0215748","title":"Increased ABCA1 activity protects against atherosclerosis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":221,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; Xenon Pharmaceuticals (Canada); Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"ABCA1; Efflux; Cholesterol; Reverse cholesterol transport; Apolipoprotein E; Genetically modified mouse; Phospholipid; Transgene; Chemistry; Transporter; In vivo; Biology; Endocrinology; Lipoprotein; Internal medicine; Biochemistry; Medicine; Gene; Membrane; Genetics","score_opus":0.14440987041581818,"score_gpt":0.35980648760842343,"score_spread":0.21539661719260525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233455462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921441,0.0039137295,0.00092497654,0.00053172105,0.00017643093,0.00002596746,0.00029436735,0.00028793278,0.0017008152],"genre_scores_gemma":[0.9925052,0.0022279182,0.00044502033,0.00024786647,0.00010957881,0.00004111381,0.00074721914,0.000036343798,0.0036397127],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9997569,0.000056460238,0.000023171324,0.00003187303,0.00004937293,0.000082314946],"domain_scores_gemma":[0.9995503,0.000055221986,0.00008613464,0.00009629002,0.00005430066,0.00015773524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211771,0.00044840708,0.0010657965,0.0004362385,0.00021014079,0.0004743743,0.00030862718,0.00054448645,0.003563857],"category_scores_gemma":[0.00036983017,0.0002643001,0.00030018616,0.00024617816,0.0003241891,0.00027778614,0.00028390178,0.001681349,0.0008560809],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038935347,0.0011454958,0.00095244026,0.00014247207,0.0000905207,0.00017389646,0.000031014635,0.00011851779,0.9759493,0.00035555998,0.0009202716,0.016227039],"study_design_scores_gemma":[0.002333106,0.03155331,0.054062482,0.00010090909,0.00055776397,0.0022648245,0.00014757091,0.0020284744,0.88389146,0.0010467275,0.021948574,0.00006495329],"about_ca_topic_score_codex":0.00039886122,"about_ca_topic_score_gemma":0.00034394552,"teacher_disagreement_score":0.003563857,"about_ca_system_score_codex":0.00019382374,"about_ca_system_score_gemma":0.00023249765,"threshold_uncertainty_score":0.01192224},"labels":[],"label_agreement":null},{"id":"W4234935234","doi":"10.1172/jci0216551","title":"Hot new therapy for sepsis and the acute respiratory distress syndrome","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Sepsis; Acute respiratory distress; Intensive care medicine; Medicine; Respiratory distress; Respiratory system; Bioinformatics; Immunology; Internal medicine; Lung; Biology; Surgery","score_opus":0.1638049174077532,"score_gpt":0.3966959609612309,"score_spread":0.2328910435534777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4234935234","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011306736,0.90676206,0.001775925,0.039832447,0.013165086,0.00007220365,0.00006673557,0.0000882508,0.026930632],"genre_scores_gemma":[0.11248998,0.7369099,0.003949937,0.05057922,0.035313755,0.00024022737,0.00020259329,0.00004587908,0.060268573],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997533,0.000089145055,0.000014890503,0.000024482533,0.000084256724,0.00003390322],"domain_scores_gemma":[0.9998091,0.00008158521,0.000037792728,0.000008616109,0.00002334359,0.000039632665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005343548,0.00035780077,0.00046769012,0.00054879615,0.00036939397,0.0005092698,0.00027801824,0.0009587447,0.007224948],"category_scores_gemma":[0.0004689423,0.00008566548,0.0002469111,0.00026355323,0.0006148539,0.00082052854,0.00059461594,0.0013063349,0.0013928019],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013578866,0.0003896145,0.0013094372,0.0020189201,0.0001153661,0.0019200061,0.00032135413,0.00019941118,0.018681398,0.026086489,0.11296555,0.8346346],"study_design_scores_gemma":[0.00034692104,0.0012113174,0.0044200257,0.0005564867,0.000076656135,0.003572172,0.0001388078,0.00024180266,0.0029420927,0.0078176325,0.9786526,0.000023422608],"about_ca_topic_score_codex":0.00013167533,"about_ca_topic_score_gemma":0.00056641066,"teacher_disagreement_score":0.007224948,"about_ca_system_score_codex":0.0002782585,"about_ca_system_score_gemma":0.00032270097,"threshold_uncertainty_score":0.024169862},"labels":[],"label_agreement":null},{"id":"W4235081779","doi":"10.1172/jci200112346","title":"Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":250,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Health Research Institutes; National Institutes of Health; University of Alberta; Alexander and Margaret Stewart Trust","keywords":"Calreticulin; DNA vaccination; Cancer research; Antigen; Immunotherapy; Immunology; MHC class I; Biology; Cancer; CD8; Medicine; Immune system; Internal medicine","score_opus":0.05023108018379265,"score_gpt":0.3201335877642197,"score_spread":0.26990250758042705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4235081779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99140024,0.0018538076,0.004231422,0.00013485264,0.000054110536,0.00013951107,0.00011947874,0.0000705544,0.0019959954],"genre_scores_gemma":[0.99418133,0.0006404864,0.0037027525,0.00007991586,0.000018513982,0.00008264955,0.00021402325,0.000009832823,0.0010704511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974567,0.00006717083,0.00001891719,0.000044361404,0.000057993082,0.00006581964],"domain_scores_gemma":[0.99988997,0.00002432315,0.000033585507,0.000013672706,0.000010026642,0.000028442824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026885042,0.00044544277,0.00030162776,0.00027900818,0.0000899107,0.00024291419,0.0001803082,0.00062022667,0.0010112566],"category_scores_gemma":[0.00017000528,0.00014410079,0.0002911257,0.000121778896,0.00033841887,0.0002465474,0.00021830095,0.0010515592,0.00021940314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026892667,0.00027172093,0.0002329356,0.00007093695,0.000007837494,0.000049600054,0.0000125890765,0.00017533755,0.9947102,0.00021913684,0.000040245683,0.0039405064],"study_design_scores_gemma":[0.00018108386,0.0038216985,0.0039514294,0.000013233269,0.000032593303,0.00054080837,0.000017429542,0.0018781929,0.98693514,0.00009217731,0.0025313082,0.000005023798],"about_ca_topic_score_codex":0.00012865454,"about_ca_topic_score_gemma":0.0002477983,"teacher_disagreement_score":0.0010112566,"about_ca_system_score_codex":0.00021144096,"about_ca_system_score_gemma":0.00027096027,"threshold_uncertainty_score":0.0033829808},"labels":[],"label_agreement":null},{"id":"W4235864214","doi":"10.1172/jci200421838","title":"High-level β-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Genentech; National Institutes of Health; Stem Cell Network","keywords":"Biology; Haematopoiesis; Stem cell; Cord blood; Viral vector; Transgene; Transduction (biophysics); Genetic enhancement; Molecular biology; Progenitor cell; Transplantation; Globin; CD34; Severe combined immunodeficiency; Myeloid; Virology; Gene; Cancer research; Immunology; Cell biology; Genetics; Recombinant DNA; Medicine","score_opus":0.08391455691124541,"score_gpt":0.36417505667063726,"score_spread":0.2802604997593918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4235864214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884133,0.00070014363,0.009138102,0.0000641044,0.000013140976,0.00006659157,0.00016873486,0.00011902032,0.001316793],"genre_scores_gemma":[0.993115,0.00037926048,0.0039802827,0.000043048996,0.0000066340663,0.000026200834,0.0004123808,0.00004743625,0.0019897588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999764,0.00004473839,0.000023754308,0.000046173158,0.00008382492,0.000037537586],"domain_scores_gemma":[0.99984324,0.000029722863,0.00003980129,0.000033082633,0.000028041115,0.000026131911],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034124608,0.00020888129,0.0001541773,0.00020570161,0.00012185312,0.00046549074,0.00012998843,0.00020553712,0.00088870886],"category_scores_gemma":[0.00020435097,0.00012827126,0.000120483855,0.00011331841,0.00023118242,0.00012594156,0.00017514786,0.00049045915,0.00043526816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023466455,0.000009741981,0.00031787032,0.000008624845,0.0000018957203,0.00002579708,0.000020383774,0.00002492663,0.99806815,0.00006823572,0.000014110098,0.0014167282],"study_design_scores_gemma":[0.0000073739075,0.00014082008,0.0026162104,0.000005236399,0.000011974457,0.00047923942,0.000017915632,0.00059749535,0.994491,0.000035144607,0.001595538,0.0000020902164],"about_ca_topic_score_codex":0.0005597563,"about_ca_topic_score_gemma":0.0005877368,"teacher_disagreement_score":0.00088870886,"about_ca_system_score_codex":0.00024454878,"about_ca_system_score_gemma":0.00023006847,"threshold_uncertainty_score":0.00297302},"labels":[],"label_agreement":null},{"id":"W4236064436","doi":"10.1172/jci200523334","title":"Glycyrrhizic acid alters Kaposi sarcoma–associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Center for AIDS Research, University of Washington; York University; National Institute of Allergy and Infectious Diseases; Elsa U. Pardee Foundation","keywords":"Lytic cycle; Virus latency; Biology; Virology; Kaposi's sarcoma-associated herpesvirus; Apoptosis; Cell cycle checkpoint; Carcinogenesis; Cancer research; Latent Virus; Immunology; Gene; Viral replication; Cell cycle; Virus; Herpesviridae; Genetics","score_opus":0.0776230949872205,"score_gpt":0.38079920013569046,"score_spread":0.30317610514846993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236064436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99820495,0.00067526905,0.0003249794,0.0000392128,0.000014029853,0.000012131039,0.00005739822,0.000025337058,0.00064670254],"genre_scores_gemma":[0.9982994,0.0005300984,0.00041951478,0.000024093359,0.00000515979,0.000009992245,0.0000790241,0.000005284892,0.0006274908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999273,0.000019075025,0.0000060584903,0.000008100988,0.0000147810015,0.00002462597],"domain_scores_gemma":[0.9999441,0.000010017855,0.000015792091,0.000008711669,0.000004657851,0.000016813492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001004105,0.0002459173,0.0001667693,0.00017248305,0.00010964725,0.0001962328,0.0001182569,0.0002458936,0.00072413293],"category_scores_gemma":[0.00009702072,0.000094301875,0.00014986155,0.00009614256,0.00017082097,0.00015677279,0.000100603036,0.0004572582,0.00017369643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030624992,0.0000872061,0.00008059994,0.0000149412035,0.0000038176063,0.000037334434,0.0000061475203,0.00002787035,0.998211,0.000037716894,0.000012552212,0.0011746172],"study_design_scores_gemma":[0.00018532219,0.0030933358,0.0051274565,0.0000053664094,0.00003498371,0.00039232933,0.000029752531,0.0006190322,0.989249,0.00011368107,0.0011454952,0.000004148335],"about_ca_topic_score_codex":0.00025270204,"about_ca_topic_score_gemma":0.00029538627,"teacher_disagreement_score":0.00072413293,"about_ca_system_score_codex":0.00014384503,"about_ca_system_score_gemma":0.0001324599,"threshold_uncertainty_score":0.002422452},"labels":[],"label_agreement":null},{"id":"W4236765824","doi":"10.1172/jci0213946","title":"Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":337,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institutes of Health; American Diabetes Association","keywords":"GLUT4; Internal medicine; Endocrinology; Insulin receptor; Insulin; Biology; Glucose uptake; GLUT1; Glucose transporter; Carbohydrate metabolism; Glycolysis; Metabolism; Insulin resistance; Medicine","score_opus":0.053149278519857374,"score_gpt":0.31416502144666303,"score_spread":0.2610157429268056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236765824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907986,0.0019883113,0.0048509417,0.000094282244,0.000022430931,0.000013032987,0.00020788683,0.0000820851,0.0019423097],"genre_scores_gemma":[0.991089,0.0016730941,0.0045621987,0.000061572144,0.00002342529,0.000039672086,0.00044420653,0.000043781987,0.0020630963],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999019,0.000011521861,0.000008243795,0.000032118638,0.000026502641,0.000019736399],"domain_scores_gemma":[0.99985874,0.000018756942,0.000051216924,0.0000158626,0.000020367517,0.000035041077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013869801,0.00025517982,0.00023479776,0.00021950503,0.00009013923,0.00032907113,0.00018145495,0.00015047369,0.0006772633],"category_scores_gemma":[0.00014921975,0.00017402403,0.00012309937,0.00014631405,0.00017212228,0.00024297116,0.00018764065,0.0004068579,0.00014361205],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011908843,0.000010610663,0.0012504098,0.000012696224,0.0000022650383,0.00006915228,0.000010402943,0.000032884425,0.9957066,0.00009732246,0.000031704272,0.0026569166],"study_design_scores_gemma":[0.00006700555,0.00051107,0.16499151,0.000017130395,0.000059824768,0.001186955,0.00009372383,0.0014873404,0.8279624,0.0004138532,0.0031951566,0.000013963271],"about_ca_topic_score_codex":0.00018688783,"about_ca_topic_score_gemma":0.00036542641,"teacher_disagreement_score":0.0006772633,"about_ca_system_score_codex":0.00022162104,"about_ca_system_score_gemma":0.0000932854,"threshold_uncertainty_score":0.0022656322},"labels":[],"label_agreement":null},{"id":"W4237732428","doi":"10.1172/jci0213359","title":"Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Universidad Nacional de La Plata; Heart and Stroke Foundation of Canada; Johns Hopkins University; American Heart Association","keywords":"Contractility; Repolarization; Heart failure; Medicine; Calcium; Heartbeat; Internal medicine; Cardiology; Endocrinology; Biology; Electrophysiology; Computer science","score_opus":0.11217918224794764,"score_gpt":0.3970746762504384,"score_spread":0.28489549400249076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4237732428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97754306,0.0024091671,0.016427847,0.00033341904,0.00017131657,0.00015093294,0.00014538811,0.00020603013,0.002612829],"genre_scores_gemma":[0.9818865,0.0018284247,0.012348244,0.00009413037,0.000048670256,0.00012767444,0.00013617224,0.000037811285,0.0034922701],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999726,0.0000426618,0.000027003241,0.00006240583,0.00007427206,0.00006764005],"domain_scores_gemma":[0.99985814,0.00003210823,0.00004821156,0.000018758523,0.00000985814,0.000032980624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030968085,0.00054732536,0.0006083226,0.0003624646,0.00019515298,0.00042302636,0.00031107044,0.0005649727,0.0011993467],"category_scores_gemma":[0.00019072222,0.00019811733,0.00031291103,0.00014060421,0.00046047685,0.00036284386,0.0003761922,0.00094109453,0.00023907064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012073781,0.000055804034,0.00006742913,0.00004017505,0.0000066052603,0.000043505217,0.000012957224,0.00010521142,0.9956233,0.00033705708,0.000044053948,0.0035432305],"study_design_scores_gemma":[0.000068856316,0.0013275738,0.0006288541,0.00000908622,0.000048890503,0.00056392374,0.000016595066,0.001295719,0.992214,0.0001114756,0.0037062906,0.000008796074],"about_ca_topic_score_codex":0.00014754412,"about_ca_topic_score_gemma":0.00040645525,"teacher_disagreement_score":0.0011993467,"about_ca_system_score_codex":0.00025041346,"about_ca_system_score_gemma":0.0002090096,"threshold_uncertainty_score":0.0040121675},"labels":[],"label_agreement":null},{"id":"W4238011279","doi":"10.1172/jci200114661","title":"Putting the brakes on arthritis: can suppressors of cytokine signaling (SOCS) suppress rheumatoid arthritis?","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Rheumatoid arthritis; Cytokine; SOCS3; Arthritis; Suppressor of cytokine signaling 1; Medicine; Suppressor; Immunology; Signal transduction; Cancer research; Biology; Internal medicine; Cell biology; Cancer","score_opus":0.07225411668738342,"score_gpt":0.35629479170852285,"score_spread":0.28404067502113944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238011279","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.39977142,0.42391667,0.006215064,0.12339457,0.016473541,0.00021671239,0.00079220365,0.0007874846,0.028432375],"genre_scores_gemma":[0.84726137,0.111240156,0.0039747525,0.02027458,0.005827955,0.00018693428,0.0003749864,0.00006606499,0.010793163],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995522,0.00009931837,0.00003384604,0.000031955187,0.000104825296,0.00017778187],"domain_scores_gemma":[0.9995721,0.00008559565,0.00008950633,0.000039098468,0.00006601325,0.00014773208],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011228813,0.0006749569,0.001155493,0.00041005344,0.0005722285,0.0017300097,0.0003998476,0.0012701077,0.004702644],"category_scores_gemma":[0.0013627913,0.00020496662,0.00056027726,0.00035256933,0.0020640239,0.0014258852,0.00083232246,0.0039946185,0.0012952011],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018605093,0.0019206017,0.006068707,0.0021165118,0.00060982746,0.0012263614,0.00048594328,0.0014142774,0.19948134,0.027757397,0.05997322,0.6803407],"study_design_scores_gemma":[0.011991659,0.0287496,0.031063579,0.0011115948,0.001738806,0.0045898594,0.0024627706,0.002939331,0.14484122,0.077938065,0.69218886,0.0003846144],"about_ca_topic_score_codex":0.00025577052,"about_ca_topic_score_gemma":0.0010365626,"teacher_disagreement_score":0.004702644,"about_ca_system_score_codex":0.00034509358,"about_ca_system_score_gemma":0.00084686105,"threshold_uncertainty_score":0.01573193},"labels":[],"label_agreement":null},{"id":"W4238609105","doi":"10.1172/jci0215420","title":"Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":378,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Caprion (Canada)","funders":"U.S. Public Health Service; American Heart Association","keywords":"Lactosylceramide; Caveolae; Golgi apparatus; Sphingolipid; Cell biology; Rab; Lipid raft; Sphingomyelin; Ceramide; Biology; Pinocytosis; Vesicular transport protein; Clathrin; Glycosphingolipid; Endocytosis; Chemistry; Vesicle; Biochemistry; Signal transduction; Receptor; Glycolipid; Cholesterol; GTPase; Membrane; Endoplasmic reticulum","score_opus":0.03484175087733286,"score_gpt":0.2877694204625575,"score_spread":0.2529276695852246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238609105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992554,0.0021871668,0.0026901711,0.0001618353,0.00002057964,0.000040249623,0.0001432215,0.0001237805,0.0020788885],"genre_scores_gemma":[0.99235994,0.0016792065,0.0032058076,0.000039422855,0.0000068432214,0.00002610253,0.00022349399,0.00001997594,0.0024391778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988914,0.000021482001,0.00001109352,0.000009993127,0.00003819929,0.00003020741],"domain_scores_gemma":[0.9999423,0.000007143766,0.000010324706,0.000009573621,0.000014216102,0.000016410077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021062464,0.0003669481,0.00016439443,0.00024605685,0.00025713095,0.000341553,0.00018312616,0.00032373852,0.00061152154],"category_scores_gemma":[0.00022174133,0.00011440447,0.00014766291,0.00010877756,0.00023028375,0.00019586415,0.00020022126,0.0003025266,0.00039652415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010028016,0.000017427243,0.00023771753,0.00003916607,0.0000046080104,0.00028313452,0.000013442374,0.00013545343,0.9962664,0.00046445327,0.00007705203,0.0023608422],"study_design_scores_gemma":[0.00004001987,0.0001001513,0.0025781875,0.0000070031087,0.000017928041,0.001142028,0.000033623386,0.0015358415,0.99059695,0.00018959993,0.0037526954,0.000005943552],"about_ca_topic_score_codex":0.0021457095,"about_ca_topic_score_gemma":0.0023539304,"teacher_disagreement_score":0.0021457095,"about_ca_system_score_codex":0.0006139703,"about_ca_system_score_gemma":0.000420952,"threshold_uncertainty_score":0.004454732},"labels":[],"label_agreement":null},{"id":"W4238924286","doi":"10.1172/jci200522486","title":"Ikaros integrates endocrine and immune system development","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Sunnybrook Health Science Centre; Health Sciences Centre; Mount Sinai Hospital; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Hormone; Glucocorticoid; Biology; Lymphopoiesis; Endocrine system; Population; Endocrinology; Proopiomelanocortin; Transcription factor; Haematopoiesis; Internal medicine; Immunology; Adrenocorticotropic hormone; Medicine; Stem cell; Gene; Cell biology; Genetics","score_opus":0.0809858429001423,"score_gpt":0.4030542107000146,"score_spread":0.32206836779987236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238924286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96502054,0.0073923357,0.0100006275,0.00051082205,0.00024286257,0.000030003182,0.001035847,0.0010083361,0.0147586465],"genre_scores_gemma":[0.9885151,0.0012759248,0.0021637012,0.00006456001,0.000051606497,0.000015879683,0.00073021854,0.000052188134,0.0071308683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980026,0.000021058322,0.000015095241,0.000050436374,0.00004277909,0.00007030314],"domain_scores_gemma":[0.9998373,0.000008934502,0.000038074748,0.000019557414,0.00002877746,0.000067461595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017283422,0.0003586412,0.00021617417,0.00038150424,0.00025001483,0.0004861729,0.00025778855,0.00018705043,0.0026719016],"category_scores_gemma":[0.00018303678,0.000115473194,0.00022142757,0.00015930196,0.00037083015,0.0004576358,0.00042216707,0.0005261312,0.0010466564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003151681,0.000018979987,0.0014563283,0.00004417535,0.0000059822364,0.0002060375,0.000046963734,0.000069016096,0.9883329,0.0006340016,0.00022771522,0.008642737],"study_design_scores_gemma":[0.00010041176,0.00046173725,0.050785076,0.00003650492,0.0000887301,0.0024229207,0.00037730995,0.0014507754,0.9041771,0.0019279809,0.038141258,0.000030206347],"about_ca_topic_score_codex":0.0003640535,"about_ca_topic_score_gemma":0.0006098979,"teacher_disagreement_score":0.0026719016,"about_ca_system_score_codex":0.00041973815,"about_ca_system_score_gemma":0.00029808434,"threshold_uncertainty_score":0.008938372},"labels":[],"label_agreement":null},{"id":"W4239079406","doi":"10.1172/jci200317423","title":"Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; St. Michael's Hospital; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institutes of Health; Kidney Foundation of Canada","keywords":"Podocyte; Glomerulus; Kidney disease; Biology; Renal function; Kidney; Glomerulopathy; Endocrinology; Pathology; Glomerulonephritis; Internal medicine; Proteinuria; Medicine","score_opus":0.06626429097389486,"score_gpt":0.3621689072289696,"score_spread":0.29590461625507475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239079406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968406,0.0008821011,0.0011800379,0.00006178942,0.000010736756,0.000006841824,0.00009619976,0.000041679672,0.00088001654],"genre_scores_gemma":[0.99878484,0.00037221922,0.00041323566,0.000022699367,0.000005890556,0.0000034392062,0.000067805806,0.0000052732103,0.00032463865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989676,0.000021067786,0.00000960794,0.000028346101,0.000023228733,0.000020894648],"domain_scores_gemma":[0.999894,0.000015663793,0.000036783404,0.000006762056,0.000008403693,0.000038236434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001453741,0.00023782499,0.00013439181,0.00024726047,0.000110360954,0.00015164718,0.000100997226,0.0001998394,0.00151674],"category_scores_gemma":[0.00024292205,0.000083491504,0.00011360545,0.00011348851,0.00025919013,0.00009666767,0.00020957734,0.00028052533,0.00012735839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039090647,0.000104996056,0.015245123,0.000085136955,0.000032789212,0.004664293,0.00006370683,0.0001551328,0.9685365,0.0009586521,0.00020750672,0.009555159],"study_design_scores_gemma":[0.00014082246,0.0017020362,0.42745042,0.000044036824,0.00015913606,0.09436338,0.00018750077,0.0017271652,0.46688512,0.0010003108,0.0063156206,0.0000245172],"about_ca_topic_score_codex":0.00031459928,"about_ca_topic_score_gemma":0.00040929642,"teacher_disagreement_score":0.00151674,"about_ca_system_score_codex":0.0001680644,"about_ca_system_score_gemma":0.00015677234,"threshold_uncertainty_score":0.0050739646},"labels":[],"label_agreement":null},{"id":"W4239273155","doi":"10.1172/jci200317271","title":"Mechano-oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institutes of Health","keywords":"Proinflammatory cytokine; Oxidative phosphorylation; Mitochondrion; Lung; Oxidative stress; Chemistry; Cell biology; Inflammation; Biophysics; Medicine; Biology; Immunology; Internal medicine; Biochemistry","score_opus":0.06544586043290376,"score_gpt":0.364294336853772,"score_spread":0.2988484764208682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239273155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99841845,0.0005765953,0.0006763807,0.00007090562,0.0000067504416,0.000010384159,0.00001428492,0.000011883287,0.0002143009],"genre_scores_gemma":[0.999178,0.00026650433,0.0003447964,0.000018350327,0.000009435765,0.000008937923,0.000016197133,0.0000014650366,0.0001562167],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99990404,0.000029450517,0.0000069118355,0.00001312905,0.000022209057,0.000024250137],"domain_scores_gemma":[0.9998933,0.000024014947,0.0000366806,0.000007145474,0.000011496977,0.000027347447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018336256,0.00016287068,0.00014643268,0.00010747412,0.00009738359,0.00027241185,0.00007760667,0.00022179226,0.00069346896],"category_scores_gemma":[0.0002950221,0.000102148275,0.00010430898,0.000063462554,0.00014774517,0.00019400532,0.00016794843,0.0003760047,0.00007193328],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031783836,0.000028260945,0.0007782456,0.000028880384,0.0000047825115,0.00019832386,0.000019726855,0.000037221685,0.99675983,0.000080214035,0.000021828351,0.0017248885],"study_design_scores_gemma":[0.00013758466,0.002256514,0.058345396,0.000019261428,0.000030987376,0.002380584,0.00016221256,0.0024444887,0.9326277,0.0003620368,0.0012240413,0.000009118233],"about_ca_topic_score_codex":0.00009775231,"about_ca_topic_score_gemma":0.00012889018,"teacher_disagreement_score":0.00069346896,"about_ca_system_score_codex":0.00016381047,"about_ca_system_score_gemma":0.0000618671,"threshold_uncertainty_score":0.0023198724},"labels":[],"label_agreement":null},{"id":"W4239675108","doi":"10.1172/jci200114498","title":"The clinical relevance of glycobiology","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Glycobiology; Relevance (law); Computational biology; Data science; Medicine; Biology; Computer science; Political science; Biochemistry; Glycan; Law","score_opus":0.09962641154073734,"score_gpt":0.43890452859659823,"score_spread":0.33927811705586086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239675108","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16508752,0.50230336,0.010380983,0.18773791,0.009030993,0.000121179306,0.0004121085,0.0001604687,0.12476551],"genre_scores_gemma":[0.8855789,0.084047236,0.0026993072,0.00726207,0.01783479,0.000044553908,0.00012365573,0.000039489594,0.0023700797],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99748236,0.001464508,0.0001736502,0.00020260664,0.0005501876,0.00012672295],"domain_scores_gemma":[0.98351604,0.012172281,0.0010518064,0.001136749,0.0015130391,0.00061006675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035317724,0.0004971182,0.00060650794,0.0013058642,0.00073479273,0.002490252,0.0005913926,0.001917135,0.0034542212],"category_scores_gemma":[0.021175588,0.00026810938,0.00025067863,0.0010719866,0.0040062806,0.0021238895,0.0010724734,0.0029715258,0.0007571977],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018034148,0.00028749474,0.15349628,0.0019188758,0.0001885326,0.02621595,0.0013695583,0.00088289037,0.009733515,0.16558614,0.04178007,0.5967374],"study_design_scores_gemma":[0.0002986012,0.0009730675,0.2052521,0.0021860346,0.00027884712,0.15109172,0.0030245055,0.0025786762,0.0061206142,0.29959247,0.32843885,0.0001645148],"about_ca_topic_score_codex":0.0003550835,"about_ca_topic_score_gemma":0.00032950717,"teacher_disagreement_score":0.0035317724,"about_ca_system_score_codex":0.0007648898,"about_ca_system_score_gemma":0.0012197858,"threshold_uncertainty_score":0.01867801},"labels":[],"label_agreement":null},{"id":"W4239928813","doi":"10.1172/jci200318397","title":"Salt-sensitive hypertension: if only it were as simple as rocket science","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sodium Intake and Health","field":"Nursing","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Rocket (weapon); Simple (philosophy); Salt (chemistry); Medicine; Aeronautics; Data science; Computer science; Chemistry; Engineering; Philosophy","score_opus":0.13026708466631967,"score_gpt":0.42635889791319437,"score_spread":0.2960918132468747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239928813","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07890407,0.0674327,0.005910406,0.7960234,0.02798006,0.000081526654,0.00012809476,0.00020880101,0.023330964],"genre_scores_gemma":[0.55656624,0.081552036,0.02020056,0.26429993,0.04476366,0.00020420799,0.0001279668,0.00013259624,0.03215282],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99870837,0.000537624,0.0001243012,0.0001446649,0.00036473473,0.00012026047],"domain_scores_gemma":[0.99657863,0.0013901168,0.0002778761,0.0002663068,0.0008072751,0.0006797734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0043507004,0.0003802619,0.0010346442,0.00055439427,0.0011740251,0.0022201026,0.00059395126,0.0037063705,0.003928951],"category_scores_gemma":[0.016211372,0.00019436247,0.0005039061,0.00035586584,0.0053380304,0.0071880757,0.0016532257,0.005216804,0.00092044735],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038578205,0.0016428949,0.056026593,0.0025290893,0.00051861757,0.0020192408,0.0038154512,0.00047941462,0.008789872,0.07432567,0.15764757,0.68834776],"study_design_scores_gemma":[0.0010264802,0.005801113,0.10317945,0.0064454037,0.0010893893,0.008893673,0.009827884,0.001462437,0.006621014,0.23428877,0.62075835,0.0006060529],"about_ca_topic_score_codex":0.0043105274,"about_ca_topic_score_gemma":0.008534525,"teacher_disagreement_score":0.0043507004,"about_ca_system_score_codex":0.0011668247,"about_ca_system_score_gemma":0.00264717,"threshold_uncertainty_score":0.023009002},"labels":[],"label_agreement":null},{"id":"W4239936636","doi":"10.1172/jci200319504","title":"Mammary-specific deletion of parathyroid hormone–related protein preserves bone mass during lactation","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":170,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute; National Institutes of Health; Yale University","keywords":"Lactation; Endocrinology; Internal medicine; Parathyroid hormone-related protein; Mammary gland; Bone resorption; Bone remodeling; Offspring; Biology; Parathyroid hormone; Genetically modified mouse; Transgene; Calcium; Pregnancy; Medicine; Gene; Cancer","score_opus":0.06999822060789593,"score_gpt":0.35805086183207524,"score_spread":0.2880526412241793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239936636","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993479,0.0016105904,0.0031612448,0.00021245028,0.000025316742,0.000023142853,0.00024133812,0.0001456525,0.0011013522],"genre_scores_gemma":[0.99157494,0.0014295258,0.003003179,0.000077732126,0.000026813846,0.000052365307,0.00049844035,0.000051102383,0.0032859093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998492,0.000025794829,0.000015304648,0.000028983493,0.00004007087,0.000040648247],"domain_scores_gemma":[0.99973196,0.000048415935,0.000086336426,0.00004691139,0.000016917324,0.00006944859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002337807,0.0001969924,0.00029127175,0.00023366795,0.0001160462,0.00030730944,0.00032509502,0.00029229908,0.00080932735],"category_scores_gemma":[0.00026089937,0.00019779682,0.0001571985,0.00010128821,0.0003012062,0.00018449267,0.00019511912,0.00050254934,0.00033002716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016484346,0.000025808265,0.00038945844,0.000016537228,0.000003011492,0.00006137912,0.000012008175,0.000028439306,0.99688053,0.000080536505,0.000027949442,0.0023095936],"study_design_scores_gemma":[0.00012940327,0.000940088,0.01932733,0.000020974208,0.000037847087,0.0014709246,0.00005944917,0.0005233945,0.9694827,0.00017688208,0.007822511,0.000008459465],"about_ca_topic_score_codex":0.00025338578,"about_ca_topic_score_gemma":0.00043415016,"teacher_disagreement_score":0.00080932735,"about_ca_system_score_codex":0.00018043374,"about_ca_system_score_gemma":0.00025321046,"threshold_uncertainty_score":0.002707541},"labels":[],"label_agreement":null},{"id":"W4240293768","doi":"10.1172/jci200523858","title":"Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor–BI mediate HDL-initiated signaling","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institutes of Health; Pfizer; American Heart Association","keywords":"Scavenger receptor; Enos; Cholesterol; PDZ domain; Cell biology; Chemistry; Biochemistry; Receptor; ABCA1; Biophysics; Biology; Lipoprotein; Transporter; Nitric oxide synthase","score_opus":0.0510693684934658,"score_gpt":0.35038913650931597,"score_spread":0.29931976801585014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240293768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9834289,0.0019919758,0.0106690135,0.00023524727,0.000039237802,0.00005735829,0.00022478212,0.00013974328,0.0032136801],"genre_scores_gemma":[0.99098396,0.00081565836,0.0033774262,0.0000756277,0.000017725135,0.000043893775,0.0004357562,0.000011118147,0.0042389026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999793,0.000022522396,0.00001396399,0.000037627306,0.000070347225,0.00006258746],"domain_scores_gemma":[0.9999231,0.0000076455335,0.000018399984,0.000010346567,0.000014272585,0.00002628898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018035446,0.0004210949,0.00025877997,0.00020875566,0.00029332808,0.0004993689,0.00025574127,0.00032180204,0.0009708007],"category_scores_gemma":[0.00013333315,0.00019500882,0.00036134574,0.0001686788,0.00020394279,0.00037806353,0.0005156801,0.0008712229,0.00064880284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007238546,0.000018085479,0.00018119914,0.000018806928,0.0000031186846,0.000056986828,0.000013983694,0.000032920547,0.9978903,0.00049592694,0.00002552033,0.001190952],"study_design_scores_gemma":[0.00004266699,0.000103764134,0.0065963264,0.000004613549,0.000012536789,0.0002582927,0.00003439806,0.002576341,0.9874521,0.00025349646,0.0026577797,0.000007633745],"about_ca_topic_score_codex":0.00069118274,"about_ca_topic_score_gemma":0.00048059403,"teacher_disagreement_score":0.0009708007,"about_ca_system_score_codex":0.0004865925,"about_ca_system_score_gemma":0.0002546512,"threshold_uncertainty_score":0.0035305023},"labels":[],"label_agreement":null},{"id":"W4240575818","doi":"10.1172/jci200215748","title":"Increased ABCA1 activity protects against atherosclerosis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; Xenon Pharmaceuticals (Canada); Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"ABCA1; Efflux; Cholesterol; Reverse cholesterol transport; Apolipoprotein E; Genetically modified mouse; Phospholipid; Transgene; Chemistry; Biology; In vivo; Transporter; Endocrinology; Lipoprotein; Internal medicine; Biochemistry; Medicine; Gene; Genetics","score_opus":0.14440987041581818,"score_gpt":0.35980648760842343,"score_spread":0.21539661719260525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240575818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921441,0.0039137295,0.00092497654,0.00053172105,0.00017643093,0.00002596746,0.00029436735,0.00028793278,0.0017008152],"genre_scores_gemma":[0.9925052,0.0022279182,0.00044502033,0.00024786647,0.00010957881,0.00004111381,0.00074721914,0.000036343798,0.0036397127],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9997569,0.000056460238,0.000023171324,0.00003187303,0.00004937293,0.000082314946],"domain_scores_gemma":[0.9995503,0.000055221986,0.00008613464,0.00009629002,0.00005430066,0.00015773524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211771,0.00044840708,0.0010657965,0.0004362385,0.00021014079,0.0004743743,0.00030862718,0.00054448645,0.003563857],"category_scores_gemma":[0.00036983017,0.0002643001,0.00030018616,0.00024617816,0.0003241891,0.00027778614,0.00028390178,0.001681349,0.0008560809],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038935347,0.0011454958,0.00095244026,0.00014247207,0.0000905207,0.00017389646,0.000031014635,0.00011851779,0.9759493,0.00035555998,0.0009202716,0.016227039],"study_design_scores_gemma":[0.002333106,0.03155331,0.054062482,0.00010090909,0.00055776397,0.0022648245,0.00014757091,0.0020284744,0.88389146,0.0010467275,0.021948574,0.00006495329],"about_ca_topic_score_codex":0.00039886122,"about_ca_topic_score_gemma":0.00034394552,"teacher_disagreement_score":0.003563857,"about_ca_system_score_codex":0.00019382374,"about_ca_system_score_gemma":0.00023249765,"threshold_uncertainty_score":0.01192224},"labels":[],"label_agreement":null},{"id":"W4240706633","doi":"10.1172/jci200316510","title":"Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Toll-like receptor; Endothelium; Receptor; Immunology; Medicine; Chemistry; Innate immune system; Internal medicine","score_opus":0.14493379602832548,"score_gpt":0.44348264421976286,"score_spread":0.29854884819143734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240706633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9750508,0.009208386,0.012370026,0.0006470128,0.00010565014,0.00010190658,0.0003906948,0.00020848644,0.0019169368],"genre_scores_gemma":[0.98756975,0.0024917906,0.0046333224,0.00015764275,0.00005370992,0.00012883332,0.00043111105,0.000021456992,0.0045125512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961615,0.00012374842,0.00003888099,0.000054473334,0.000086759894,0.0000799872],"domain_scores_gemma":[0.9997315,0.00002636312,0.00013081786,0.000024167117,0.000028343065,0.000058709826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037097922,0.0005494281,0.00033900578,0.0002682436,0.00017600467,0.00031694837,0.00030857715,0.0006195307,0.0018027322],"category_scores_gemma":[0.0002209893,0.00027933766,0.00043257233,0.0000919888,0.00028915674,0.000421911,0.0005431595,0.0009330039,0.00068085635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037209206,0.000028749357,0.00042586218,0.00008557521,0.000006488608,0.00019896947,0.0000095307905,0.0000640148,0.9971781,0.00012913537,0.000050303715,0.0014511571],"study_design_scores_gemma":[0.000065032335,0.00098207,0.020378126,0.000033920194,0.00005742899,0.0012403249,0.00007396616,0.0017880083,0.970942,0.00022259654,0.004202747,0.00001378698],"about_ca_topic_score_codex":0.00019942428,"about_ca_topic_score_gemma":0.00017937824,"teacher_disagreement_score":0.0018027322,"about_ca_system_score_codex":0.0002723846,"about_ca_system_score_gemma":0.00023553052,"threshold_uncertainty_score":0.006030798},"labels":[],"label_agreement":null},{"id":"W4240738684","doi":"10.1172/jci200214060","title":"Human sex hormone–binding globulin variants associated with hyperandrogenism and ovarian dysfunction","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; Western University","funders":"Canadian Institutes of Health Research; Fondation de France","keywords":"Sex hormone-binding globulin; Hyperandrogenism; Endocrinology; Internal medicine; Biology; Polycystic ovary; Proband; Androgen; Medicine; Genetics; Mutation; Insulin; Hormone; Gene; Insulin resistance","score_opus":0.10517156090991676,"score_gpt":0.338584032913545,"score_spread":0.23341247200362825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240738684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99841416,0.0004614931,0.00020846433,0.00010007008,0.000016036609,0.000011112155,0.00008939966,0.000009347544,0.00068984943],"genre_scores_gemma":[0.99913627,0.00016246543,0.00018408497,0.000057004243,0.000034048855,0.000003484631,0.00008079977,0.0000043890263,0.0003373955],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99977905,0.000054092674,0.000025466717,0.000044932673,0.000054051423,0.000042330914],"domain_scores_gemma":[0.9995246,0.00016136421,0.00015129981,0.000026074698,0.00003277275,0.00010390525],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019345945,0.00072353834,0.0002920988,0.00087117933,0.0003944936,0.00026289996,0.00017376884,0.000666211,0.0018610497],"category_scores_gemma":[0.0009483221,0.00017210635,0.00023638067,0.00062655954,0.00054413546,0.00013560842,0.00026604126,0.00031800137,0.0002010751],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020281668,0.00021937293,0.6015786,0.0001824659,0.00027342676,0.23740353,0.0014308651,0.00040898946,0.12958944,0.0009457828,0.001068985,0.024870412],"study_design_scores_gemma":[0.00011754176,0.000593855,0.59952134,0.000033771572,0.0001382771,0.3834937,0.00028031558,0.00037707496,0.011913382,0.0006189324,0.0028867947,0.000025009691],"about_ca_topic_score_codex":0.0011305097,"about_ca_topic_score_gemma":0.0012560359,"teacher_disagreement_score":0.0018610497,"about_ca_system_score_codex":0.00017646544,"about_ca_system_score_gemma":0.00021621046,"threshold_uncertainty_score":0.0062257648},"labels":[],"label_agreement":null},{"id":"W4240851324","doi":"10.1172/jci200215463","title":"Circulating levels of IGF-1 directly regulate bone growth and density","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Novo Nordisk; National Institutes of Health; Aarhus Universitet","keywords":"Endocrinology; Internal medicine; Bone growth; Protein subunit; Pathophysiology; Growth factor; Cortical bone; Osteoporosis; Endocrine system; Biology; Chemistry; Receptor; Gene; Medicine; Anatomy; Biochemistry; Hormone","score_opus":0.12298556000926676,"score_gpt":0.33974059068095425,"score_spread":0.2167550306716875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240851324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9130557,0.051399056,0.009653409,0.0009254811,0.0002992749,0.000094044124,0.0010755822,0.00046598594,0.02303133],"genre_scores_gemma":[0.98086506,0.0072722966,0.003822837,0.00017770503,0.00008442063,0.00006129297,0.0002990994,0.00002007726,0.00739727],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99994993,0.000009315406,0.0000027137858,0.0000100261905,0.000017308628,0.000010744701],"domain_scores_gemma":[0.99993217,0.000014060537,0.000016108437,0.0000038601415,0.000011107919,0.00002275511],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009840174,0.00025958457,0.00016192858,0.00015922343,0.00007397494,0.000308827,0.00012334505,0.00017722255,0.0016385411],"category_scores_gemma":[0.00018654976,0.00006996064,0.000054263695,0.00008706702,0.00020108832,0.00010860022,0.00011432301,0.00031465056,0.0003019152],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020205874,0.0002640428,0.013690905,0.0003384881,0.000037522805,0.0004714507,0.00009346461,0.00017973455,0.85174394,0.0012341772,0.0017891377,0.12813643],"study_design_scores_gemma":[0.0005046493,0.0032257934,0.37318778,0.0002200017,0.00014749919,0.002477336,0.00028208425,0.0022031667,0.5391406,0.0021099064,0.07646621,0.00003497841],"about_ca_topic_score_codex":0.00056375837,"about_ca_topic_score_gemma":0.0007174778,"teacher_disagreement_score":0.0016385411,"about_ca_system_score_codex":0.00030156708,"about_ca_system_score_gemma":0.00014443412,"threshold_uncertainty_score":0.005481422},"labels":[],"label_agreement":null},{"id":"W4241254331","doi":"10.1172/jci200421846","title":"EphB6-null mutation results in compromised T cell function","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Université de Montréal; Roche Organ Transplant Research Foundation; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"Biology; Kinase; Immune system; Phosphorylation; T cell; T-cell receptor; Immunology; Cell biology","score_opus":0.1541023220908831,"score_gpt":0.37287259020978414,"score_spread":0.21877026811890105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4241254331","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992573,0.001090778,0.002823889,0.00017104483,0.0000783565,0.000021831731,0.0013976864,0.0001948433,0.0016485531],"genre_scores_gemma":[0.9882063,0.0010690488,0.002851595,0.0000879441,0.000035209774,0.000026502536,0.0011437614,0.00010876531,0.0064708064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996861,0.000045856643,0.000062810184,0.00006987057,0.00008651734,0.00004887167],"domain_scores_gemma":[0.99962986,0.000056819055,0.00012068776,0.000036308953,0.0000176011,0.00013869327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017327246,0.0006141034,0.0003922324,0.00046170046,0.00015954746,0.00041503794,0.0002571324,0.00071763503,0.0036621878],"category_scores_gemma":[0.00019944481,0.00023862542,0.0003530762,0.00017364114,0.0004778921,0.00029777188,0.00038526743,0.001051455,0.0013755294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019555858,0.000028990751,0.00021120236,0.00003646162,0.000011203183,0.0004456801,0.000013157767,0.0000782457,0.9977428,0.00015829569,0.000055085336,0.0010234875],"study_design_scores_gemma":[0.00006594127,0.0004227788,0.007123084,0.000020891966,0.000053581454,0.0060417294,0.00005884109,0.0016930096,0.97979,0.00028885863,0.0044280123,0.000013261163],"about_ca_topic_score_codex":0.0001941913,"about_ca_topic_score_gemma":0.00025099504,"teacher_disagreement_score":0.0036621878,"about_ca_system_score_codex":0.00017963619,"about_ca_system_score_gemma":0.00012099251,"threshold_uncertainty_score":0.012251258},"labels":[],"label_agreement":null},{"id":"W4241637932","doi":"10.1172/jci200525148","title":"Caffey disease: an unlikely collagenopathy","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Osteomyelitis and Bone Disorders Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Shriners Hospitals for Children - Canada; Montreal Children's Hospital","funders":"Shriners Hospitals for Children; McGill University","keywords":"Osteogenesis imperfecta; Missense mutation; Hyperostosis; Dentinogenesis imperfecta; Pathology; Connective tissue; Mutation; Ehlers–Danlos syndrome; Medicine; Genetics; Biology; Anatomy; Gene","score_opus":0.1258456460204865,"score_gpt":0.4478869165702676,"score_spread":0.32204127054978104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4241637932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8970592,0.026984688,0.0033858093,0.040301364,0.0049284757,0.000116607785,0.00030123015,0.00021117239,0.026711475],"genre_scores_gemma":[0.9761964,0.0063842786,0.001046782,0.002911904,0.009292071,0.000017247887,0.000095122654,0.000015741838,0.0040404503],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.9997173,0.000031357573,0.000024938381,0.00008294493,0.000055110566,0.000088469744],"domain_scores_gemma":[0.9989379,0.00041268932,0.00026132824,0.00006304001,0.00010252204,0.00022245027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000329619,0.00074392295,0.0004710327,0.00066586415,0.0007167226,0.00074386795,0.00066913775,0.0041545923,0.0024593358],"category_scores_gemma":[0.0034952294,0.00020164742,0.00023055157,0.00027263662,0.0011757604,0.00082849513,0.0003517728,0.000733546,0.00044200773],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008096268,0.0001261183,0.050329726,0.000396889,0.000091455375,0.8809316,0.00035196383,0.00014353824,0.013398863,0.009867023,0.014582876,0.028970322],"study_design_scores_gemma":[0.00023595952,0.0002611134,0.027728803,0.0001261747,0.00012561209,0.92778283,0.00028786203,0.0005318766,0.0029781717,0.0035132007,0.036400165,0.000028175218],"about_ca_topic_score_codex":0.00089338014,"about_ca_topic_score_gemma":0.0009867233,"teacher_disagreement_score":0.0041545923,"about_ca_system_score_codex":0.0004059163,"about_ca_system_score_gemma":0.00027624375,"threshold_uncertainty_score":0.008227348},"labels":[],"label_agreement":null},{"id":"W4243628135","doi":"10.1172/jci200316409","title":"Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":215,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of Calgary; University of Alberta; Simon Fraser University; University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia; Fondation pour la Recherche Médicale; Children's Hospital Foundation; Michael Smith Health Research BC; Canadian Diabetes Association","keywords":"Immunology; Peripheral blood; NOD mice; Autoimmunity; Type 1 diabetes; Major histocompatibility complex; Autoimmune diabetes; Nod; Avidity; Diabetes mellitus; Autoimmune disease; Medicine; Peripheral; Antigen; Biology; Immune system; Endocrinology; Antibody; Internal medicine","score_opus":0.020659726289164557,"score_gpt":0.2762189708846089,"score_spread":0.2555592445954443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243628135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98968226,0.0007991827,0.007889787,0.000036792106,0.000013832954,0.000058937447,0.00033373752,0.00023186009,0.00095366145],"genre_scores_gemma":[0.99190336,0.0003637849,0.0065227337,0.00006499194,0.000015839694,0.00008783275,0.0003811137,0.000026815464,0.00063353917],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992755,0.00024055163,0.00006738133,0.0001841173,0.00015968799,0.00007270242],"domain_scores_gemma":[0.99899584,0.00027761736,0.00030084228,0.00013252022,0.0000648036,0.000228391],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006883502,0.00042662272,0.00029867401,0.00085406523,0.00013960479,0.00042809808,0.00018189303,0.00057319144,0.00076302537],"category_scores_gemma":[0.0009708211,0.0002641658,0.00011162903,0.00026729138,0.00021776315,0.00028602334,0.00021451965,0.000749058,0.00034058985],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008993502,0.00018906171,0.013750082,0.00004013971,0.000013372382,0.000087541935,0.000030433534,0.00021677875,0.9796429,0.00009644032,0.000033078097,0.005000649],"study_design_scores_gemma":[0.00021969239,0.0039577894,0.13878581,0.00004116372,0.000071743576,0.002225486,0.00006304416,0.012589386,0.8403232,0.00056153414,0.0011369076,0.000024175974],"about_ca_topic_score_codex":0.00012557187,"about_ca_topic_score_gemma":0.00015939707,"teacher_disagreement_score":0.00085406523,"about_ca_system_score_codex":0.00013243566,"about_ca_system_score_gemma":0.00007519835,"threshold_uncertainty_score":0.0036403537},"labels":[],"label_agreement":null},{"id":"W4244218181","doi":"10.1172/jci200523219","title":"Effects of the PPARγ agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsches Krebsforschungszentrum; Takeda Pharmaceuticals North America","keywords":"Very low-density lipoprotein; Endocrinology; Lipolysis; Internal medicine; Lipoprotein lipase; Pioglitazone; Chemistry; Apolipoprotein B; Lipoprotein; Insulin resistance; Insulin; Diabetes mellitus; Adipose tissue; Medicine; Type 2 diabetes; Cholesterol","score_opus":0.011448691505976404,"score_gpt":0.26987557982307353,"score_spread":0.25842688831709715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244218181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833782,0.013030158,0.00021303244,0.0004339142,0.0001613999,0.00008882369,0.00019799624,0.00003281669,0.0024636483],"genre_scores_gemma":[0.9924412,0.005016153,0.000595288,0.0006308438,0.00012253269,0.00009144059,0.00031576338,0.000008043131,0.0007786483],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997335,0.000088887595,0.00005375882,0.00003686944,0.00004842811,0.00003863309],"domain_scores_gemma":[0.9995981,0.00010941788,0.00007598189,0.000026776544,0.000047238602,0.0001425196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054031075,0.00045177893,0.0013824234,0.00045042593,0.00054135127,0.0006048587,0.00017384441,0.0005825482,0.0011408541],"category_scores_gemma":[0.00091157004,0.00027379475,0.00074564415,0.00079932454,0.00015861323,0.00029086936,0.00027605603,0.0012118351,0.00020674433],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.18090707,0.015895704,0.44488385,0.0013920424,0.0031313067,0.0047039622,0.00062944856,0.001031023,0.06299902,0.00022414813,0.0023036508,0.28189874],"study_design_scores_gemma":[0.00821481,0.04164593,0.92772233,0.00020880658,0.0034498214,0.0019399249,0.00071832084,0.001307423,0.006101661,0.00028184307,0.008329891,0.00007925063],"about_ca_topic_score_codex":0.0012661007,"about_ca_topic_score_gemma":0.0020395177,"teacher_disagreement_score":0.0013824234,"about_ca_system_score_codex":0.00032731707,"about_ca_system_score_gemma":0.0003902596,"threshold_uncertainty_score":0.003816545},"labels":[],"label_agreement":null},{"id":"W4244256516","doi":"10.1172/jci200421623","title":"West Nile virus: a growing concern?","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"West Nile virus; Geography; Virology; Virus; Epidemiology; Ecology; Environmental protection; Biology; Medicine","score_opus":0.08991115154285552,"score_gpt":0.4029599011995962,"score_spread":0.3130487496567407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244256516","genre_codex":"review","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0061658714,0.6246418,0.0009774291,0.34737682,0.011892834,0.000018595174,0.00013531264,0.00010800078,0.008683315],"genre_scores_gemma":[0.05583784,0.77888197,0.0017528979,0.11777655,0.023686882,0.000027217671,0.0004302518,0.000047335463,0.021559045],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994178,0.0001631561,0.00006128971,0.00009789063,0.00017487694,0.000085088206],"domain_scores_gemma":[0.99854374,0.00024941732,0.00022254048,0.000033499757,0.0006202431,0.00033050368],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013102026,0.0004683129,0.0009122546,0.00045000663,0.0004901383,0.002972666,0.00046256458,0.0045617116,0.009874549],"category_scores_gemma":[0.0026993696,0.00019815586,0.000245986,0.0008389765,0.0011445251,0.00351263,0.0006195667,0.0022887536,0.0036213053],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024070559,0.00007892579,0.011028611,0.003065457,0.000047325928,0.002653954,0.0005269159,0.00007840904,0.0042912215,0.004686628,0.27819416,0.6951077],"study_design_scores_gemma":[0.000044320164,0.00032572154,0.012709821,0.0016726766,0.000068977984,0.009453693,0.0036180762,0.00013836435,0.0005860093,0.0052484544,0.96610117,0.0000327155],"about_ca_topic_score_codex":0.0029139982,"about_ca_topic_score_gemma":0.004141094,"teacher_disagreement_score":0.009874549,"about_ca_system_score_codex":0.00078557496,"about_ca_system_score_gemma":0.002211841,"threshold_uncertainty_score":0.03303367},"labels":[],"label_agreement":null},{"id":"W4244341139","doi":"10.1172/jci10088","title":"Airway plumbing","year":2000,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Airway; Medicine; Biology; Surgery","score_opus":0.2677553386444419,"score_gpt":0.4770366443903058,"score_spread":0.2092813057458639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244341139","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006903477,0.9934824,0.0005756146,0.0005259594,0.0009477311,0.000020096079,0.00002604468,0.000036803183,0.0036949127],"genre_scores_gemma":[0.010577719,0.97674567,0.00088697416,0.0012610448,0.0017380451,0.000041334977,0.00010914979,0.00001078568,0.008629286],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996427,0.00006073764,0.000059569742,0.000076201686,0.000117318064,0.000043430835],"domain_scores_gemma":[0.99972826,0.000079188845,0.000077911485,0.000016310185,0.00006648119,0.000031784428],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003865018,0.0013277062,0.0020250846,0.0025571878,0.0005393532,0.0012246998,0.00084372377,0.0017850854,0.009198499],"category_scores_gemma":[0.0012028905,0.00030138285,0.0006824671,0.0014543432,0.000846999,0.0019082804,0.0012082291,0.0019763364,0.005684349],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013244447,0.000062751285,0.0006739071,0.007540182,0.000057859277,0.0030037572,0.000052806212,0.00013376336,0.0026191394,0.0009833834,0.026958453,0.95778155],"study_design_scores_gemma":[0.00009831077,0.00051663816,0.007926645,0.00864578,0.00046489565,0.07038192,0.00027912008,0.0003722391,0.0037149028,0.0024976868,0.9050451,0.000056705438],"about_ca_topic_score_codex":0.00068803015,"about_ca_topic_score_gemma":0.0015817599,"teacher_disagreement_score":0.009198499,"about_ca_system_score_codex":0.00044666667,"about_ca_system_score_gemma":0.0009591778,"threshold_uncertainty_score":0.03077203},"labels":[],"label_agreement":null},{"id":"W4244724776","doi":"10.1172/jci0214817","title":"Parathyroid hormone is essential for normal fetal bone formation","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bone health and treatments","field":"Medicine","cited_by":235,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University; McGill University Health Centre","funders":"Medical Research Council","keywords":"Internal medicine; Endocrinology; Parathyroid hormone; Fetus; Anabolism; Cartilage; Ossification; Long bone; Medicine; Chemistry; Biology; Anatomy; Calcium; Pregnancy","score_opus":0.11568784558306382,"score_gpt":0.39960700421157735,"score_spread":0.2839191586285135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244724776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9554905,0.021858152,0.0096574165,0.0007920183,0.00015702735,0.000054371165,0.0014835375,0.0006904612,0.009816381],"genre_scores_gemma":[0.9909117,0.0035487108,0.0025571596,0.0000611929,0.000037343736,0.000023602206,0.0005418533,0.000046460984,0.0022719176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963737,0.000049923045,0.000031831525,0.00005077997,0.00018013282,0.00004993833],"domain_scores_gemma":[0.99952257,0.00011543963,0.00009297702,0.00006490719,0.00007628835,0.00012792317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018882014,0.0002052694,0.00023696241,0.0003153007,0.00019082591,0.00049054215,0.00030660562,0.00035848533,0.0013526698],"category_scores_gemma":[0.0007025235,0.00026145543,0.00012406637,0.00011289046,0.00036460345,0.00019099866,0.00033647884,0.0004227452,0.0006246337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024200128,0.000015918858,0.0011284563,0.000079052355,0.00000537859,0.00046322084,0.000035404268,0.00008280367,0.98921543,0.000569073,0.00020143035,0.007961813],"study_design_scores_gemma":[0.000113077345,0.00054379815,0.04548657,0.000057703663,0.000048807644,0.006099504,0.00012598578,0.00093045464,0.90436447,0.0013287509,0.040879264,0.000021551386],"about_ca_topic_score_codex":0.00088683434,"about_ca_topic_score_gemma":0.0007448029,"teacher_disagreement_score":0.0013526698,"about_ca_system_score_codex":0.00032735418,"about_ca_system_score_gemma":0.00043200262,"threshold_uncertainty_score":0.004525125},"labels":[],"label_agreement":null},{"id":"W4245234573","doi":"10.1172/jci200319159","title":"Autosomal dominant pseudohypoparathyroidism type Ib is associated with a heterozygous microdeletion that likely disrupts a putative imprinting control element of GNAS","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital; McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"GNAS complex locus; Pseudohypoparathyroidism; Imprinting (psychology); Genomic imprinting; Genetics; Biology; Endocrinology; Internal medicine; Medicine; Gene; Parathyroid hormone","score_opus":0.038505553832486036,"score_gpt":0.3210772784450016,"score_spread":0.28257172461251556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245234573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98766035,0.0014347754,0.002605842,0.0006088757,0.000096988995,0.00007585613,0.00066911237,0.00024499436,0.006603137],"genre_scores_gemma":[0.99691427,0.00043957142,0.0011397501,0.000086027925,0.000086014625,0.000019701294,0.00020738751,0.000029142017,0.0010780697],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.99971646,0.000033628232,0.00003029956,0.00007379042,0.000092068665,0.000053697084],"domain_scores_gemma":[0.99939954,0.00017707031,0.00026286306,0.000029308403,0.000015475685,0.00011580571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014406549,0.0015174898,0.00058204035,0.0013428695,0.0004858282,0.00042411961,0.00066304044,0.0012709728,0.00301088],"category_scores_gemma":[0.001184197,0.00042749877,0.00033313074,0.0013640599,0.001085222,0.00027200233,0.0005374882,0.0007144075,0.00057228445],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007641109,0.00008640927,0.038355555,0.00020728527,0.00012702237,0.7993055,0.00029471898,0.0002344506,0.1472294,0.0013533441,0.0009585597,0.011083696],"study_design_scores_gemma":[0.00006667515,0.0002911632,0.06826382,0.000019161338,0.00008712225,0.92024547,0.00010036493,0.00035799888,0.008482209,0.0005275468,0.0015348784,0.00002354746],"about_ca_topic_score_codex":0.0017239641,"about_ca_topic_score_gemma":0.0019141737,"teacher_disagreement_score":0.00301088,"about_ca_system_score_codex":0.0004022685,"about_ca_system_score_gemma":0.00035103897,"threshold_uncertainty_score":0.0100723505},"labels":[],"label_agreement":null},{"id":"W4245476440","doi":"10.1172/jci200215595","title":"Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"National Institutes of Health","keywords":"Stimulation; Internal medicine; Endocrinology; Heart rate; Receptor; Blood pressure; Glucagon-like peptide-1; Glucagon; Medicine; Chemistry; Biology; Hormone; Diabetes mellitus","score_opus":0.11063628208817494,"score_gpt":0.35321322626305457,"score_spread":0.24257694417487963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245476440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888166,0.0042181956,0.002860126,0.0001834956,0.0001243539,0.000041348118,0.00016430159,0.00013800344,0.0034535672],"genre_scores_gemma":[0.992343,0.0036580295,0.0017074202,0.00014127229,0.00010097768,0.00005381338,0.00018967889,0.000011548867,0.001794261],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994075,0.000013338174,0.0000035779788,0.000013118704,0.000016607954,0.000012655287],"domain_scores_gemma":[0.99993455,0.000015603657,0.000018961879,0.0000046623622,0.0000058072087,0.00002041523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006556022,0.0002937196,0.00025282084,0.00014277642,0.000088800196,0.0001434634,0.000082552564,0.00016729505,0.0021838965],"category_scores_gemma":[0.00014828784,0.000089184025,0.0001540336,0.00009436043,0.00019603306,0.00010117585,0.00012931897,0.00043415785,0.00019869734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047872256,0.00007614843,0.00046702486,0.00006496807,0.000009783207,0.000103402,0.000015845375,0.000022188056,0.98705393,0.000040338633,0.00009902367,0.011568791],"study_design_scores_gemma":[0.00020956939,0.00860003,0.15064968,0.00005054352,0.00007963427,0.0018321727,0.00013753297,0.0010639504,0.83151114,0.000416731,0.0054239556,0.000025057892],"about_ca_topic_score_codex":0.0001521164,"about_ca_topic_score_gemma":0.00029907923,"teacher_disagreement_score":0.0021838965,"about_ca_system_score_codex":0.00012877533,"about_ca_system_score_gemma":0.00008345632,"threshold_uncertainty_score":0.007305801},"labels":[],"label_agreement":null},{"id":"W4245825595","doi":"10.1172/jci200113397","title":"The multiple contributions of thyroid hormone to heat production","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Thyroid; Hormone; Endocrinology; Internal medicine; Biology; Medicine","score_opus":0.0740917467028041,"score_gpt":0.39549065093451446,"score_spread":0.32139890423171036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245825595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88837904,0.093085,0.007367698,0.0023454288,0.00064126414,0.00009088375,0.00029459086,0.00006037759,0.0077356393],"genre_scores_gemma":[0.9878682,0.0076965145,0.0015548528,0.00020774812,0.00038070144,0.000044209017,0.00008085382,0.00003094043,0.0021360386],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99962735,0.00009913392,0.000028337437,0.00006376489,0.00010813464,0.000073306896],"domain_scores_gemma":[0.99915314,0.0004172297,0.0000857098,0.000088133405,0.00009678416,0.00015885133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043315327,0.00059448986,0.00069278595,0.00045129406,0.00042782005,0.0012733138,0.00040301084,0.00051344064,0.0016079075],"category_scores_gemma":[0.0012973438,0.0004029019,0.0005993213,0.00039418443,0.0008297896,0.00053664687,0.00065777183,0.0011262746,0.00018633234],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02364436,0.0004978738,0.13106678,0.0016215233,0.0014450316,0.0053247623,0.0012020904,0.004544952,0.6365345,0.0051020263,0.002098385,0.18691763],"study_design_scores_gemma":[0.00051319733,0.002260723,0.8608043,0.00025965073,0.0010101586,0.0039369506,0.0011948728,0.003437226,0.10939239,0.006482629,0.010584434,0.00012349043],"about_ca_topic_score_codex":0.0042410614,"about_ca_topic_score_gemma":0.004971839,"teacher_disagreement_score":0.0042410614,"about_ca_system_score_codex":0.0009364086,"about_ca_system_score_gemma":0.00087176927,"threshold_uncertainty_score":0.008432746},"labels":[],"label_agreement":null},{"id":"W4247220599","doi":"10.1172/jci200420373","title":"Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genital Health and Disease","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health; University of New Brunswick","funders":"Menzies Centre for Australian Studies, King's College London, University of London; British Skin Foundation","keywords":"Lichen sclerosus; Autoantibody; Serology; Epitope; Immunology; Medicine; Pathology; Antigen; Antibody","score_opus":0.1774250684095468,"score_gpt":0.43692646583601846,"score_spread":0.25950139742647166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247220599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845989,0.0021109194,0.009805329,0.00013761333,0.0000605092,0.00020202922,0.00022738251,0.00025397626,0.002603398],"genre_scores_gemma":[0.9861573,0.0005218263,0.011332796,0.00015526108,0.00006284269,0.00015816832,0.0005481151,0.0000121543435,0.0010515258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894935,0.0004510613,0.000083518986,0.00013597179,0.00028902438,0.00009110485],"domain_scores_gemma":[0.99898356,0.000600801,0.00009119507,0.000085295156,0.00015842756,0.000080767386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010016093,0.000672021,0.00042895385,0.0011068613,0.00021482751,0.00033818715,0.00027919177,0.000737038,0.0014510493],"category_scores_gemma":[0.0024718728,0.0002649707,0.00012876293,0.00040601846,0.00023384846,0.00026381167,0.00024287644,0.0005735262,0.000774393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075814174,0.0017519861,0.2575026,0.00029144113,0.00018776442,0.0008539582,0.0004545756,0.0006781058,0.6423007,0.00028798025,0.0017781764,0.0931546],"study_design_scores_gemma":[0.00086116145,0.011770928,0.64336365,0.0001790562,0.00037667112,0.020933647,0.00040293962,0.018203543,0.28910753,0.0007761959,0.013927383,0.00009730587],"about_ca_topic_score_codex":0.00039774965,"about_ca_topic_score_gemma":0.00038425764,"teacher_disagreement_score":0.0014510493,"about_ca_system_score_codex":0.0001735521,"about_ca_system_score_gemma":0.00009844154,"threshold_uncertainty_score":0.005297065},"labels":[],"label_agreement":null},{"id":"W4247285076","doi":"10.1172/jci0215336","title":"A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institutes of Health; Elizabeth Glaser Pediatric AIDS Foundation","keywords":"Cell biology; Chemokine; Transcription factor; Biology; T cell; Proinflammatory cytokine; EIF4E; p38 mitogen-activated protein kinases; MAPK/ERK pathway; Effector; Kinase; Inflammation; Translation (biology); Immunology; Immune system; Messenger RNA; Gene; Genetics","score_opus":0.07463683282965859,"score_gpt":0.33247707445285823,"score_spread":0.25784024162319963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247285076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99122834,0.0028483707,0.002900294,0.00026172528,0.000084510255,0.00002349096,0.00008157369,0.00010706953,0.0024646516],"genre_scores_gemma":[0.99592113,0.0008816536,0.0015924184,0.00005651493,0.000045807312,0.000020399404,0.00008733009,0.000023492608,0.0013712189],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998729,0.000034421337,0.000011127372,0.00002540938,0.000021369537,0.000034846427],"domain_scores_gemma":[0.99985456,0.000032070962,0.0000413639,0.000023918066,0.000017632983,0.000030457271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020551204,0.00026605444,0.0002206253,0.00015987031,0.00016673845,0.0003896683,0.00015290942,0.00021103573,0.0014048658],"category_scores_gemma":[0.0002525722,0.00012455415,0.00017507689,0.00007345539,0.00031146867,0.00028923558,0.00019595605,0.0004979721,0.00043187971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016288525,0.00001340639,0.00009053911,0.000015491602,0.0000010541554,0.00003737935,0.000008345965,0.000028312314,0.99854964,0.00012534988,0.00001914991,0.0009483967],"study_design_scores_gemma":[0.000031489926,0.00035283342,0.0040408885,0.00000709833,0.000010267044,0.00018954504,0.000028727956,0.0006107635,0.9923779,0.00015420695,0.0021907226,0.0000055665932],"about_ca_topic_score_codex":0.000065965905,"about_ca_topic_score_gemma":0.00014472487,"teacher_disagreement_score":0.0014048658,"about_ca_system_score_codex":0.0002267286,"about_ca_system_score_gemma":0.000118156924,"threshold_uncertainty_score":0.004699707},"labels":[],"label_agreement":null},{"id":"W4248542691","doi":"10.1172/jci200523683","title":"Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institutes of Health; Queen's University; University of Pennsylvania","keywords":"ATP synthase; Platelet; Gene knockdown; Prostaglandin; Chemistry; Endocrinology; Medicine; Internal medicine; Cell biology; Biology; Biochemistry; Enzyme; Gene","score_opus":0.050830465635370456,"score_gpt":0.38516132413207393,"score_spread":0.33433085849670346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4248542691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98850584,0.0018210129,0.0038930017,0.00028089253,0.00015948492,0.00010882951,0.0016698255,0.00021806636,0.0033430925],"genre_scores_gemma":[0.99002737,0.0009812268,0.0018851461,0.00011908412,0.000016461534,0.00016915843,0.0008922749,0.000037463902,0.005871885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996666,0.00003542751,0.00004243953,0.000087050284,0.00009657714,0.000071973474],"domain_scores_gemma":[0.99981743,0.00003424609,0.000047091926,0.000023166098,0.000014841368,0.00006320935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020417453,0.0002718994,0.00034931768,0.00021354563,0.0001576371,0.00034699016,0.0002135717,0.0003467007,0.0019641959],"category_scores_gemma":[0.00014872555,0.00017040565,0.00023158925,0.00014483779,0.0003154703,0.00020273532,0.00018316876,0.00079893245,0.0003302459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039477175,0.000076651864,0.00024023268,0.000073184776,0.000009238342,0.0000738888,0.000035100642,0.00009072578,0.99651164,0.00022844029,0.00017123214,0.002094969],"study_design_scores_gemma":[0.000071795526,0.0009171655,0.006682934,0.000011006957,0.00003923994,0.00021028733,0.00006233701,0.0012832271,0.9858518,0.00008003857,0.0047812066,0.0000089247715],"about_ca_topic_score_codex":0.00059385644,"about_ca_topic_score_gemma":0.001151563,"teacher_disagreement_score":0.0019641959,"about_ca_system_score_codex":0.00025420365,"about_ca_system_score_gemma":0.0002386962,"threshold_uncertainty_score":0.006570816},"labels":[],"label_agreement":null},{"id":"W4248953039","doi":"10.1172/jci0214596","title":"Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Canadian Institutes of Health Research; National Institutes of Health; American Heart Association","keywords":"Internal medicine; Endocrinology; CD36; Insulin resistance; Hyperinsulinemia; Insulin; Biology; Glucose uptake; Fructose; Triglyceride; Glycogen; Glycogen synthase; Fatty acid; Lipotoxicity; Medicine; Cholesterol; Biochemistry","score_opus":0.05133764479509177,"score_gpt":0.33714139656338066,"score_spread":0.28580375176828887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4248953039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99812967,0.00031532522,0.0008541774,0.000096118885,0.000012061131,0.000010108985,0.00027042307,0.000048639286,0.0002634877],"genre_scores_gemma":[0.9943441,0.000641956,0.0023538982,0.00008952616,0.000012446813,0.000049794136,0.00054924696,0.00009372013,0.0018653171],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996729,0.00006684631,0.000048142265,0.000081777864,0.000054886415,0.00007541163],"domain_scores_gemma":[0.9996239,0.00005283525,0.00012384527,0.000038347036,0.00002046176,0.00014064618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022668754,0.0005881439,0.00043602567,0.00088052655,0.00023778915,0.0004416893,0.00032429947,0.0006053576,0.0020277395],"category_scores_gemma":[0.0003065422,0.00045770057,0.00030500765,0.00029950895,0.00066511537,0.00032185725,0.00037133603,0.00086451595,0.0005274681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005889691,0.000043629694,0.00049102976,0.000018747405,0.0000064989918,0.00010945828,0.000021726015,0.000037399866,0.9980654,0.00007095521,0.00002027474,0.0005259023],"study_design_scores_gemma":[0.0003146591,0.00091852824,0.022992862,0.000033958167,0.00011231666,0.0025185454,0.00013955458,0.0015249107,0.9690239,0.00033686918,0.0020514869,0.00003242206],"about_ca_topic_score_codex":0.00050280854,"about_ca_topic_score_gemma":0.00063212693,"teacher_disagreement_score":0.0020277395,"about_ca_system_score_codex":0.0003387039,"about_ca_system_score_gemma":0.00015268591,"threshold_uncertainty_score":0.0067834854},"labels":[],"label_agreement":null},{"id":"W4249074033","doi":"10.1172/jci200318589","title":"A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interaction","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Medical Research Council; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo; Wellcome Trust","keywords":"Biology; Hypopituitarism; Haploinsufficiency; Genetics; Forebrain; Corepressor; Repressor; Endocrinology; Phenotype; Gene; Transcription factor","score_opus":0.06938387433390723,"score_gpt":0.3538282214987097,"score_spread":0.28444434716480244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249074033","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971648,0.00022362165,0.00090715016,0.000099652665,0.000026447542,0.000024009627,0.0002939311,0.00012839514,0.0011320414],"genre_scores_gemma":[0.99735826,0.00017620246,0.0004867691,0.00003287094,0.000028381633,0.000008769359,0.00018172778,0.000028678693,0.0016982978],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998142,0.000013877012,0.000024033414,0.00006996281,0.00004695813,0.000030918727],"domain_scores_gemma":[0.9997477,0.00005806381,0.0000868952,0.000015456691,0.0000082103725,0.00008364714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001347592,0.0013160488,0.00042094622,0.00087755354,0.00035758712,0.00024824147,0.0004985734,0.000854791,0.0032205868],"category_scores_gemma":[0.0003211924,0.0002909304,0.00035318817,0.00043676863,0.00088757277,0.00023784811,0.00057939795,0.00055592245,0.00049829384],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059005397,0.00014589442,0.014851621,0.00015241925,0.00010988655,0.4643769,0.00046935276,0.00033661132,0.50968057,0.0010130974,0.00049237424,0.0077812625],"study_design_scores_gemma":[0.00009995645,0.00079337077,0.09953916,0.000029104716,0.000108978005,0.7989931,0.0001993124,0.0013075109,0.0947453,0.0003496035,0.003777368,0.000057260466],"about_ca_topic_score_codex":0.0006833688,"about_ca_topic_score_gemma":0.00066492654,"teacher_disagreement_score":0.0032205868,"about_ca_system_score_codex":0.0002724137,"about_ca_system_score_gemma":0.00022323217,"threshold_uncertainty_score":0.010773957},"labels":[],"label_agreement":null},{"id":"W4249844052","doi":"10.1172/jci0215316","title":"Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Nitric oxide; Chemistry; Biophysics; Stimulation; Protein subunit; Carbon monoxide; Pharmacology; Agonist; Biochemistry; Internal medicine; Medicine; Biology; Receptor; Gene","score_opus":0.09247713089352295,"score_gpt":0.3271748391372642,"score_spread":0.23469770824374125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249844052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9664373,0.022312934,0.007339743,0.0007284319,0.00016265888,0.00011455379,0.00012354626,0.00006499195,0.0027157892],"genre_scores_gemma":[0.99268216,0.0041705878,0.0020067813,0.00017706768,0.00006147934,0.00009862728,0.000060688602,0.0000061325068,0.00073637575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996531,0.00009392213,0.000035971134,0.00006478875,0.00006213749,0.00009007191],"domain_scores_gemma":[0.9997186,0.00006974901,0.000060822127,0.000027994764,0.00004097909,0.00008188095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004713242,0.00042529468,0.00047951107,0.00022354806,0.00020321702,0.00038944013,0.00035143728,0.00070170517,0.00054381683],"category_scores_gemma":[0.0003414591,0.0002071431,0.000387278,0.00009490576,0.0005723406,0.0005996516,0.00028313114,0.0006849533,0.00012689509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005456082,0.000047559097,0.0008264914,0.00014045877,0.0000136381295,0.00030896085,0.00004711317,0.000088468136,0.99520457,0.0007920006,0.00003260491,0.0019526379],"study_design_scores_gemma":[0.00024619268,0.0017150604,0.07794921,0.00006273989,0.00013563778,0.002471756,0.0003261898,0.0029491594,0.9084866,0.0017422889,0.0038778742,0.000037426278],"about_ca_topic_score_codex":0.00020553771,"about_ca_topic_score_gemma":0.00027855605,"teacher_disagreement_score":0.00070170517,"about_ca_system_score_codex":0.00037344353,"about_ca_system_score_gemma":0.00030806952,"threshold_uncertainty_score":0.002709508},"labels":[],"label_agreement":null},{"id":"W4250041627","doi":"10.1172/jci200318114","title":"The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hepatitis C virus research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; McMaster University; University Health Network; Hamilton Health Sciences; University of Toronto; Canada Research Chairs; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Heart and Stroke Foundation of Canada","keywords":"Prothrombinase; Virology; Medicine; Thrombosis; Immunology; Viral hepatitis; Thrombin; Internal medicine","score_opus":0.0959930368233978,"score_gpt":0.4329421008410549,"score_spread":0.3369490640176571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250041627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997785,0.00093356555,0.00069171767,0.000042688993,0.0000040437685,0.000012488622,0.000051685565,0.000020244837,0.0004585907],"genre_scores_gemma":[0.99877495,0.00035739658,0.00034245555,0.0000329371,0.000009776066,0.000013034574,0.00008840531,0.000004684295,0.00037638246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999032,0.00004131182,0.000009594533,0.00001385944,0.000014579468,0.000017547965],"domain_scores_gemma":[0.9999044,0.000014101413,0.000034232253,0.000011491448,0.000007556153,0.00002833432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021215725,0.00030114676,0.00014852545,0.00039370486,0.00010451139,0.00019263318,0.00006954717,0.0002562455,0.00077090744],"category_scores_gemma":[0.0001899779,0.00009824937,0.00012635608,0.000116500116,0.00030772225,0.00010059421,0.00015400126,0.00022787463,0.00016044237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010733193,0.00006406809,0.005284461,0.0000598672,0.000010036426,0.00075251446,0.00005416319,0.000072090595,0.9898318,0.00013175589,0.000048528196,0.0026173843],"study_design_scores_gemma":[0.00023496537,0.0024653133,0.31491637,0.000047431186,0.00011225296,0.014737539,0.00021826712,0.0024879638,0.65967727,0.00053573376,0.0045457403,0.000021189953],"about_ca_topic_score_codex":0.00021130049,"about_ca_topic_score_gemma":0.00018801782,"teacher_disagreement_score":0.00077090744,"about_ca_system_score_codex":0.00014650194,"about_ca_system_score_gemma":0.00007390732,"threshold_uncertainty_score":0.0025789142},"labels":[],"label_agreement":null},{"id":"W4251638612","doi":"10.1172/jci200317038","title":"Randall’s plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Kidney Stones and Urolithiasis Treatments","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institutes of Health","keywords":"Basement membrane; Medicine; Anatomy; Calcium; Pathology; Internal medicine","score_opus":0.03936582350563315,"score_gpt":0.33095617237809266,"score_spread":0.2915903488724595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4251638612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991279,0.0001972847,0.00016605703,0.000017358512,0.000002171916,0.0000078843605,0.000008038019,0.0000046970113,0.00046855962],"genre_scores_gemma":[0.99946684,0.000068852365,0.0003026553,0.000010963679,0.0000072042003,0.0000028626773,0.000015465383,0.0000016376351,0.00012356522],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99977475,0.000052600226,0.000026086747,0.00005726043,0.00004934717,0.00004000382],"domain_scores_gemma":[0.99948573,0.0001004168,0.0002254804,0.00004837402,0.000048006998,0.00009196564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035253994,0.00034113938,0.00035607742,0.0007796554,0.0004607976,0.0002939277,0.00013619754,0.00036172813,0.0016721261],"category_scores_gemma":[0.0010512137,0.00021708733,0.00021605982,0.00029660342,0.00041052126,0.0005240141,0.0003414843,0.0002865578,0.0001934008],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020983466,0.00013850631,0.8820605,0.00012765241,0.00007672936,0.013300671,0.0013542239,0.00009639927,0.089651085,0.0004608827,0.00012888323,0.010506066],"study_design_scores_gemma":[0.000044309734,0.0009577432,0.9332991,0.000015693942,0.00008278228,0.044335578,0.0006526444,0.00024688497,0.01911495,0.00034828053,0.0008837637,0.000018265988],"about_ca_topic_score_codex":0.00045585632,"about_ca_topic_score_gemma":0.00053197367,"teacher_disagreement_score":0.0016721261,"about_ca_system_score_codex":0.00009292449,"about_ca_system_score_gemma":0.0001465007,"threshold_uncertainty_score":0.0055937767},"labels":[],"label_agreement":null},{"id":"W4251764915","doi":"10.1172/jci200215506","title":"Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"National Institute of Child Health and Human Development","keywords":"Rolipram; Xylazine; Phosphodiesterase; Pentobarbital; Ketamine; Pharmacology; Chemistry; Barbiturate; Endocrinology; Internal medicine; Anesthesia; Medicine; Enzyme; Biochemistry","score_opus":0.05860576188850777,"score_gpt":0.32529729899747234,"score_spread":0.2666915371089646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4251764915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866991,0.0013150981,0.0075117704,0.0003457619,0.00010121691,0.00014690362,0.002005985,0.00031574996,0.0015583864],"genre_scores_gemma":[0.97241163,0.002298071,0.011481872,0.00027467925,0.00005184147,0.0003972216,0.0024608274,0.00023493015,0.0103889955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996044,0.000055076656,0.00006820785,0.00012238487,0.00007042927,0.00007962657],"domain_scores_gemma":[0.9994997,0.000055484714,0.00021937788,0.00003850541,0.000024415707,0.00016257305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030828954,0.0010834783,0.00047780966,0.0012639656,0.00029419686,0.00038802784,0.00050265715,0.00083025947,0.0031832082],"category_scores_gemma":[0.00022472793,0.0006348877,0.00084232,0.00028634313,0.0007068228,0.00045100765,0.00041786494,0.0016202643,0.0005506318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031111817,0.000079444355,0.0002406771,0.000034294866,0.000011204042,0.00009699911,0.000019786392,0.00005523028,0.99796104,0.00016882697,0.000043812335,0.0009776115],"study_design_scores_gemma":[0.00025012568,0.0016888209,0.011982114,0.000044048364,0.00009122821,0.0010351822,0.00010476157,0.0015338598,0.97851485,0.00016910248,0.0045653824,0.000020643478],"about_ca_topic_score_codex":0.00077821803,"about_ca_topic_score_gemma":0.0014981827,"teacher_disagreement_score":0.0031832082,"about_ca_system_score_codex":0.00053144834,"about_ca_system_score_gemma":0.00036504655,"threshold_uncertainty_score":0.010648906},"labels":[],"label_agreement":null},{"id":"W4251941545","doi":"10.1172/jci200422831","title":"Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; York University; University of Minnesota; National Institutes of Health; Alzheimer's Association","keywords":"Rolipram; Long-term potentiation; CREB; Synaptic plasticity; Neuroscience; Protein kinase A; Neurotransmission; Presenilin; Donepezil; Amyloid precursor protein; Phosphodiesterase; Pharmacology; Alzheimer's disease; Medicine; Chemistry; Biology; Internal medicine; Cell biology; Kinase; Biochemistry; Receptor; Dementia; Disease; Enzyme","score_opus":0.13273456056925528,"score_gpt":0.40745234143284087,"score_spread":0.27471778086358556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4251941545","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99466056,0.0017458149,0.0011975946,0.00026894838,0.000088175155,0.000042906424,0.00029863653,0.00036843293,0.0013288263],"genre_scores_gemma":[0.989223,0.0016014387,0.0024173982,0.00016136943,0.00006186084,0.000117736905,0.0006794191,0.000038358474,0.0056994534],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997768,0.000028143199,0.000024768164,0.000037364087,0.00005688868,0.00007612154],"domain_scores_gemma":[0.99973136,0.00001543109,0.000079940284,0.000040880932,0.000030166315,0.00010222656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029346067,0.0008757013,0.00096694357,0.00067872455,0.00027140163,0.00036383263,0.0004660064,0.0008116567,0.0010477953],"category_scores_gemma":[0.00018472942,0.00023964024,0.00044337925,0.00019378752,0.00034397485,0.00046119592,0.00021221553,0.0016035945,0.0006080771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013361954,0.00078781834,0.00037206555,0.000053816515,0.000029226592,0.0004277571,0.00004004547,0.000058910377,0.991139,0.00009249475,0.00015928829,0.005503405],"study_design_scores_gemma":[0.00060065207,0.015508619,0.012392827,0.00003782173,0.00015907196,0.0023287951,0.00007337683,0.0015892391,0.9637179,0.00033483442,0.0032286597,0.000028179997],"about_ca_topic_score_codex":0.0005732089,"about_ca_topic_score_gemma":0.0006973529,"teacher_disagreement_score":0.0010477953,"about_ca_system_score_codex":0.00027537678,"about_ca_system_score_gemma":0.00024883647,"threshold_uncertainty_score":0.00350523},"labels":[],"label_agreement":null},{"id":"W4252720287","doi":"10.1172/jci200112877","title":"The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; University of British Columbia; Deutsche Forschungsgemeinschaft; American Heart Association","keywords":"Monocyte; Chemokine; Chemotaxis; CCL2; Immunology; Endothelium; CCR2; Cell biology; Chemokine receptor; Medicine; Chemistry; Biology; Inflammation; Receptor; Internal medicine","score_opus":0.09456878079758113,"score_gpt":0.35152690419764654,"score_spread":0.2569581234000654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252720287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950734,0.0021585268,0.0012482757,0.0000880183,0.00003381932,0.000021429936,0.00018365298,0.000043889842,0.0011490594],"genre_scores_gemma":[0.99358386,0.0016891639,0.0015363835,0.00006835101,0.00002618924,0.00002838735,0.00037782543,0.000012545487,0.002677333],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998447,0.000035399033,0.000011116663,0.000017177004,0.000023882114,0.000067790555],"domain_scores_gemma":[0.99992394,0.000016056021,0.000013663212,0.000009395201,0.00001083861,0.000026033027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016055592,0.0002760763,0.00022918744,0.00012745267,0.0001342823,0.00027994634,0.000115071656,0.0001906955,0.0017804445],"category_scores_gemma":[0.00014136093,0.00009218849,0.00011241972,0.00007366717,0.00017260449,0.00014305906,0.00011155571,0.00042209425,0.0006878987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022117831,0.000042548447,0.000186705,0.000027433876,0.0000020619486,0.000040596096,0.000013658034,0.000009813103,0.99842656,0.000054887038,0.000064555905,0.0009101354],"study_design_scores_gemma":[0.000039489743,0.0007639578,0.0074240514,0.0000091719485,0.000013160656,0.00062775804,0.00003087004,0.000299018,0.98866326,0.000033275206,0.0020911633,0.000004754706],"about_ca_topic_score_codex":0.00041246458,"about_ca_topic_score_gemma":0.00091505604,"teacher_disagreement_score":0.0017804445,"about_ca_system_score_codex":0.00021714198,"about_ca_system_score_gemma":0.0002054174,"threshold_uncertainty_score":0.005956173},"labels":[],"label_agreement":null},{"id":"W4252795044","doi":"10.1172/jci0215595","title":"Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":430,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"National Institutes of Health","keywords":"Endocrinology; Internal medicine; Glucagon-like peptide-1; Adrenal medulla; Catecholamine; Receptor; Biology; Medicine; Diabetes mellitus; Type 2 diabetes","score_opus":0.06906751738822468,"score_gpt":0.31581175006090023,"score_spread":0.24674423267267553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252795044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855004,0.006012866,0.003083547,0.00023492362,0.00015419557,0.000050041886,0.00018756215,0.00015193665,0.004624379],"genre_scores_gemma":[0.99029934,0.004775632,0.0020435413,0.00016476371,0.00012373853,0.00006373008,0.00020550791,0.000012893604,0.0023108562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999305,0.000016352518,0.000004177305,0.000015403873,0.000019133955,0.00001431716],"domain_scores_gemma":[0.99993396,0.000015315889,0.000018636245,0.0000044823532,0.0000061212077,0.000021616877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007634664,0.00032125457,0.00027333442,0.00014328431,0.00009315703,0.00015475776,0.00009071412,0.0001852284,0.002394471],"category_scores_gemma":[0.00017282795,0.00009525573,0.00013908553,0.000103227845,0.00020972587,0.000109747874,0.00013658224,0.00049726205,0.00023145898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005597549,0.000100153055,0.00047448892,0.00007691241,0.000010132497,0.00013358804,0.00001585994,0.00002398242,0.98472923,0.000048734793,0.00012197271,0.013705329],"study_design_scores_gemma":[0.00023102366,0.008393917,0.14210266,0.00005658952,0.00007749941,0.0024167646,0.0001312127,0.0010261841,0.8385673,0.00042486726,0.0065457327,0.000026211548],"about_ca_topic_score_codex":0.00013786861,"about_ca_topic_score_gemma":0.0002671049,"teacher_disagreement_score":0.002394471,"about_ca_system_score_codex":0.00014116737,"about_ca_system_score_gemma":0.00008742427,"threshold_uncertainty_score":0.008010268},"labels":[],"label_agreement":null},{"id":"W4253244719","doi":"10.1172/jci0214080","title":"The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":765,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Peroxisome proliferator-activated receptor; Diabetic cardiomyopathy; Endocrinology; Internal medicine; Beta oxidation; Biology; Heart failure; Cardiomyopathy; Fatty acid metabolism; Glucose uptake; Fatty acid; Receptor; Insulin; Medicine; Metabolism; Biochemistry","score_opus":0.07587762791124153,"score_gpt":0.32346502885247663,"score_spread":0.2475874009412351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253244719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931631,0.00078867737,0.0024609824,0.00016846712,0.00009723608,0.000046836445,0.00040556455,0.00010070131,0.002768382],"genre_scores_gemma":[0.9924057,0.00097438775,0.0025018097,0.0001394456,0.00002417597,0.00008304584,0.0006711488,0.000039980576,0.003160354],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998037,0.000039102943,0.000026949408,0.000035627338,0.000049057257,0.000045563804],"domain_scores_gemma":[0.99980587,0.000022400201,0.00006699325,0.000031739943,0.000009685288,0.000063380474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020386561,0.00039065973,0.00027295394,0.0003623164,0.00023957467,0.00036755909,0.00014035667,0.00031911203,0.0015045309],"category_scores_gemma":[0.00016436512,0.00020236392,0.00023167119,0.00027221013,0.00032311532,0.0001571456,0.00029887285,0.00080384,0.0003994196],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041234112,0.000066913904,0.0008227388,0.000025848487,0.000008427561,0.00040216133,0.000014504209,0.000078526195,0.99670357,0.00028150238,0.000053247568,0.0011302168],"study_design_scores_gemma":[0.0003530382,0.003476146,0.058055066,0.000049340284,0.00010866468,0.010601859,0.00023999078,0.0020270853,0.9111943,0.0008592646,0.01300039,0.000034898658],"about_ca_topic_score_codex":0.00021192516,"about_ca_topic_score_gemma":0.00031363918,"teacher_disagreement_score":0.0015045309,"about_ca_system_score_codex":0.00018859324,"about_ca_system_score_gemma":0.00016236411,"threshold_uncertainty_score":0.005033195},"labels":[],"label_agreement":null},{"id":"W4253249668","doi":"10.1172/jci200524186","title":"Lack of MEF2A mutations in coronary artery disease","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"Joint Genome Institute; Canadian Institutes of Health Research; Lawrence Berkeley National Laboratory; University of Ottawa; Heart and Stroke Foundation of Canada; U.S. Department of Energy","keywords":"Proband; Coronary artery disease; Genetics; CAD; Genotyping; Coding region; Mutation; Biology; Medicine; Internal medicine; Genotype; Gene","score_opus":0.20520920108308602,"score_gpt":0.4549021402352849,"score_spread":0.2496929391521989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253249668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99798965,0.0007243549,0.00026574783,0.000059696995,0.00001143166,0.0000036332008,0.000083134226,0.000012214446,0.0008499803],"genre_scores_gemma":[0.9993075,0.00014361592,0.00012933539,0.000034935427,0.000016237467,0.0000025807335,0.00009150712,0.000004213163,0.0002700699],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99983954,0.000026450061,0.000025355737,0.00004397542,0.000042239637,0.000022481854],"domain_scores_gemma":[0.99960166,0.00013177497,0.000082661885,0.000034704663,0.000047921032,0.000101252896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027778745,0.00023121727,0.00026237438,0.00057099154,0.00023461875,0.00022748607,0.00017231784,0.00036981396,0.0022808956],"category_scores_gemma":[0.0012169379,0.00012551429,0.00008664825,0.00016286386,0.00029890906,0.00019440103,0.0002047711,0.00018324984,0.0003340766],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014515271,0.00035179086,0.59351873,0.00015880034,0.00014197569,0.022539409,0.0005637886,0.00019186697,0.3510244,0.0011947374,0.001169885,0.027693111],"study_design_scores_gemma":[0.000105919964,0.00055509846,0.88870245,0.000050634604,0.00010166464,0.090224616,0.00018719205,0.00072444417,0.013974459,0.0009972372,0.0043574376,0.000018752016],"about_ca_topic_score_codex":0.00041157415,"about_ca_topic_score_gemma":0.0004942243,"teacher_disagreement_score":0.0022808956,"about_ca_system_score_codex":0.00008292228,"about_ca_system_score_gemma":0.00008054025,"threshold_uncertainty_score":0.007630348},"labels":[],"label_agreement":null},{"id":"W4253388582","doi":"10.1172/jci200213971","title":"Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada); Hospital for Sick Children; Heart and Stroke Foundation; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; University of Toronto; Heart and Stroke Foundation of Canada","keywords":"Myocarditis; Coxsackievirus; Virology; Enterovirus; Immunology; Medicine; Microbiology; Biology; Virus; Internal medicine","score_opus":0.1749567905483057,"score_gpt":0.43113673614328857,"score_spread":0.25617994559498286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253388582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99586856,0.000952206,0.0009840559,0.00017395322,0.000053876374,0.00006872137,0.00054531964,0.00012218858,0.0012311433],"genre_scores_gemma":[0.9918682,0.00093287317,0.001759474,0.00015241318,0.000035675217,0.00022585975,0.0009300829,0.00005848969,0.0040368377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997012,0.00004786948,0.000032950014,0.000073270516,0.000051075607,0.00009362107],"domain_scores_gemma":[0.9996458,0.00003229917,0.000097793614,0.000029495412,0.000020438396,0.00017405205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003260986,0.00094339316,0.0005401578,0.0011453158,0.00047054692,0.00054093526,0.0003102675,0.001101438,0.00311432],"category_scores_gemma":[0.00023261142,0.0005902419,0.0005897212,0.00031180232,0.00053376635,0.0005136195,0.00029180764,0.0021769705,0.00074290525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011143561,0.00045583292,0.0004530331,0.00004975607,0.000011366994,0.00015308594,0.00004310047,0.00006369453,0.99661595,0.00020967414,0.000100756086,0.0007293848],"study_design_scores_gemma":[0.00079646904,0.0062482734,0.055736903,0.000073943265,0.00012465252,0.0030108148,0.00025187567,0.0031078327,0.92484564,0.0005653512,0.0051864833,0.000051699495],"about_ca_topic_score_codex":0.00040430494,"about_ca_topic_score_gemma":0.0005795681,"teacher_disagreement_score":0.00311432,"about_ca_system_score_codex":0.00048529226,"about_ca_system_score_gemma":0.00025274156,"threshold_uncertainty_score":0.010418415},"labels":[],"label_agreement":null},{"id":"W4254753682","doi":"10.1172/jci45819","title":"Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Sympathetic nervous system; Sympathetic activity; Medicine; Endocrinology; Internal medicine; Cell biology; Chemistry; Biology; Blood pressure; Heart rate","score_opus":0.06414447237831229,"score_gpt":0.3673238305480064,"score_spread":0.3031793581696941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254753682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976197,0.0007106344,0.00073839305,0.00022196653,0.00006742626,0.000025383471,0.0001144382,0.000043721688,0.0004583591],"genre_scores_gemma":[0.9970137,0.0010298749,0.00061159837,0.00017220573,0.000050930576,0.000058729234,0.00017855405,0.00002194551,0.00086237106],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998091,0.00004746047,0.0000117342115,0.000053946547,0.000027867916,0.00005000558],"domain_scores_gemma":[0.99979335,0.000022024624,0.00006135024,0.00003895046,0.000008000729,0.00007631281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034937199,0.00046815307,0.00044418513,0.00043970605,0.00026957013,0.00044290864,0.00023721039,0.0003966852,0.0010172368],"category_scores_gemma":[0.00031926963,0.00032339702,0.00032350002,0.00015262084,0.0011140021,0.0003704669,0.0002263422,0.001074879,0.00011216488],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022687327,0.0022288885,0.0051988466,0.00008828056,0.00011355899,0.00042473228,0.000120072895,0.00025449024,0.9563266,0.0005868881,0.0006141597,0.0113562895],"study_design_scores_gemma":[0.005240149,0.057456654,0.17271473,0.00013522881,0.00081071537,0.0030826845,0.0007076802,0.0058877817,0.74233466,0.0017095584,0.009793346,0.0001268857],"about_ca_topic_score_codex":0.00067459577,"about_ca_topic_score_gemma":0.00092064164,"teacher_disagreement_score":0.0010172368,"about_ca_system_score_codex":0.00028025478,"about_ca_system_score_gemma":0.00037763268,"threshold_uncertainty_score":0.003403008},"labels":[],"label_agreement":null},{"id":"W4255060189","doi":"10.1172/jci200215316","title":"Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Nitric oxide; Chemistry; Biophysics; Stimulation; Protein subunit; Carbon monoxide; Agonist; Pharmacology; Cell biology; Biochemistry; Internal medicine; Medicine; Biology; Receptor; Gene","score_opus":0.09247713089352295,"score_gpt":0.3271748391372642,"score_spread":0.23469770824374125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255060189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9664373,0.022312934,0.007339743,0.0007284319,0.00016265888,0.00011455379,0.00012354626,0.00006499195,0.0027157892],"genre_scores_gemma":[0.99268216,0.0041705878,0.0020067813,0.00017706768,0.00006147934,0.00009862728,0.000060688602,0.0000061325068,0.00073637575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996531,0.00009392213,0.000035971134,0.00006478875,0.00006213749,0.00009007191],"domain_scores_gemma":[0.9997186,0.00006974901,0.000060822127,0.000027994764,0.00004097909,0.00008188095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004713242,0.00042529468,0.00047951107,0.00022354806,0.00020321702,0.00038944013,0.00035143728,0.00070170517,0.00054381683],"category_scores_gemma":[0.0003414591,0.0002071431,0.000387278,0.00009490576,0.0005723406,0.0005996516,0.00028313114,0.0006849533,0.00012689509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005456082,0.000047559097,0.0008264914,0.00014045877,0.0000136381295,0.00030896085,0.00004711317,0.000088468136,0.99520457,0.0007920006,0.00003260491,0.0019526379],"study_design_scores_gemma":[0.00024619268,0.0017150604,0.07794921,0.00006273989,0.00013563778,0.002471756,0.0003261898,0.0029491594,0.9084866,0.0017422889,0.0038778742,0.000037426278],"about_ca_topic_score_codex":0.00020553771,"about_ca_topic_score_gemma":0.00027855605,"teacher_disagreement_score":0.00070170517,"about_ca_system_score_codex":0.00037344353,"about_ca_system_score_gemma":0.00030806952,"threshold_uncertainty_score":0.002709508},"labels":[],"label_agreement":null},{"id":"W4255156190","doi":"10.1172/jci200318237","title":"The fractalkine receptor CX3CR1 is a key mediator of atherogenesis","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Toronto General Hospital; University of Toronto","funders":"","keywords":"CX3CR1; Mediator; Key (lock); Receptor; Cell biology; Medicine; Chemistry; Biology; Chemokine receptor; Chemokine; Internal medicine","score_opus":0.06480258441889247,"score_gpt":0.3698281380249473,"score_spread":0.3050255536060548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255156190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.905371,0.07114834,0.008014259,0.005041349,0.0006657276,0.00014180594,0.0008562667,0.00024754493,0.008513771],"genre_scores_gemma":[0.9854321,0.0071471715,0.002618284,0.00031921506,0.00043197212,0.000042689328,0.00047540234,0.000019575938,0.0035136642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997583,0.000053062482,0.0000173187,0.000036057703,0.00008780897,0.00004741133],"domain_scores_gemma":[0.9997731,0.00004071844,0.00007288112,0.00001601253,0.00003907464,0.000058105226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035834388,0.0002550057,0.00039688722,0.00034254562,0.00026712296,0.00057972525,0.00018286948,0.00054545567,0.0013979392],"category_scores_gemma":[0.00066350226,0.00015383499,0.00017280472,0.00018748306,0.00028436392,0.0003048248,0.00026811194,0.0008813244,0.00040612608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018725833,0.000082661536,0.0033910498,0.0003361312,0.00004566075,0.0011722938,0.000100993726,0.00026916587,0.94073707,0.0032621857,0.0042149364,0.04451519],"study_design_scores_gemma":[0.00054229324,0.0021952167,0.12273692,0.00019093175,0.00024028207,0.016678417,0.00020159892,0.0046630786,0.75883776,0.0036957162,0.08993769,0.00008007175],"about_ca_topic_score_codex":0.00053996965,"about_ca_topic_score_gemma":0.00047310579,"teacher_disagreement_score":0.0013979392,"about_ca_system_score_codex":0.00055696064,"about_ca_system_score_gemma":0.0004371312,"threshold_uncertainty_score":0.0046765804},"labels":[],"label_agreement":null},{"id":"W4255918677","doi":"10.1172/jci200214036","title":"Targeted expression of a human pituitary tumor–derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research; University of Toronto; Mount Sinai Hospital","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Biology; Gene isoform; Fibroblast growth factor receptor 4; Pituitary tumors; Carcinogenesis; Pituitary gland; Receptor; Cancer research; Fibroblast growth factor receptor; Cell biology; Fibroblast growth factor; Endocrinology; Cancer; Genetics; Gene; Hormone","score_opus":0.06421812979329598,"score_gpt":0.34586182030217427,"score_spread":0.2816436905088783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255918677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96973264,0.0015057308,0.017466975,0.00020814614,0.00016888176,0.00078495796,0.0062259748,0.00047773434,0.0034289055],"genre_scores_gemma":[0.96070576,0.00144696,0.022039432,0.00009508995,0.000039923394,0.0007546279,0.0067215944,0.00029484095,0.00790175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99959403,0.00005563042,0.000057491146,0.000088801746,0.00011991042,0.00008424186],"domain_scores_gemma":[0.9997099,0.00006225253,0.00007498935,0.000058749953,0.000022561326,0.00007156421],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050929096,0.0006423408,0.00048540076,0.0006808518,0.00037022104,0.0005260758,0.0005618969,0.0004632017,0.0033774308],"category_scores_gemma":[0.00021939183,0.0004485567,0.00056107936,0.00038005298,0.00053370657,0.00020483007,0.00031834262,0.0008216775,0.0013924596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013465612,0.000035062854,0.00010132391,0.000027868728,0.000006955776,0.00013367055,0.00001945662,0.00011667762,0.99870324,0.00010790998,0.00009545345,0.00051778025],"study_design_scores_gemma":[0.000121507954,0.00047216463,0.0023470956,0.000008042671,0.000055452634,0.0011512323,0.000058166366,0.0014963384,0.98478925,0.00006320744,0.009422311,0.000015333004],"about_ca_topic_score_codex":0.00163549,"about_ca_topic_score_gemma":0.0026732476,"teacher_disagreement_score":0.0033774308,"about_ca_system_score_codex":0.00071151095,"about_ca_system_score_gemma":0.0006526193,"threshold_uncertainty_score":0.011298656},"labels":[],"label_agreement":null},{"id":"W4256533826","doi":"10.1172/jci200112067","title":"Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":229,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Amgen (Canada); Montreal Children's Hospital; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; Amgen","keywords":"Matrix metalloproteinase; Lung; Extracellular matrix; Pathology; Fibrosis; Fibroblast; Tissue inhibitor of metalloproteinase; Biology; Immunology; Chemistry; Cell biology; In vitro; Medicine; Internal medicine; Biochemistry","score_opus":0.03458430447292604,"score_gpt":0.33319961969975165,"score_spread":0.2986153152268256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256533826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906785,0.001871779,0.005008171,0.00021777334,0.00007028218,0.000065024935,0.00090523635,0.00028273388,0.00090049725],"genre_scores_gemma":[0.9880376,0.0013619612,0.003507234,0.00014866142,0.00005258197,0.00014565111,0.0016619402,0.00010497041,0.0049794773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996817,0.0000462239,0.000041534455,0.000088943874,0.00007776496,0.000063744046],"domain_scores_gemma":[0.999054,0.00013986223,0.000335466,0.00008826925,0.00005410636,0.00032824164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004613263,0.0007451099,0.0005282198,0.0007641205,0.0002844165,0.00042401406,0.00027653915,0.0007749622,0.001986802],"category_scores_gemma":[0.00034860542,0.0004005286,0.00050992414,0.00020309945,0.0006724653,0.0005661141,0.00038093314,0.0014264318,0.00055382284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032004307,0.00012156086,0.00093635597,0.000035889276,0.000009803024,0.00062524265,0.000042150565,0.00003438261,0.996228,0.00015325095,0.000074056596,0.0014192659],"study_design_scores_gemma":[0.00028164912,0.005030654,0.056421228,0.00004595205,0.00010272388,0.014712035,0.0001606517,0.0012437388,0.9170192,0.00048062563,0.0044580535,0.000043539854],"about_ca_topic_score_codex":0.00022914507,"about_ca_topic_score_gemma":0.00037890888,"teacher_disagreement_score":0.001986802,"about_ca_system_score_codex":0.0002718605,"about_ca_system_score_gemma":0.00021830802,"threshold_uncertainty_score":0.006646514},"labels":[],"label_agreement":null},{"id":"W4280493604","doi":"10.1172/jci152635","title":"mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; Université Laval; McGill University","funders":"Canadian Institutes of Health Research; Louise and Alan Edwards Foundation; Azrieli Foundation; Réseau québécois de recherche sur la douleur; Hebrew University of Jerusalem; Deutsche Forschungsgemeinschaft; International Development Research Centre; McGill University","keywords":"Nociceptor; Nociception; Hyperalgesia; Inflammation; Free nerve ending; Noxious stimulus; Neuroscience; Medicine; Immunology; Anatomy; Receptor; Biology; Internal medicine","score_opus":0.055680168993594556,"score_gpt":0.35464678822299833,"score_spread":0.29896661922940376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280493604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96727073,0.007366162,0.019819707,0.00032945286,0.0000912907,0.00005069844,0.00034279036,0.0003370897,0.004392062],"genre_scores_gemma":[0.9956715,0.0017917845,0.00178159,0.000034506193,0.000016248772,0.000021617036,0.00013603231,0.000015503088,0.0005313079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994266,0.000011090686,0.000003936993,0.000014423023,0.000012579192,0.000015247077],"domain_scores_gemma":[0.99996865,0.000004422544,0.000009961416,0.0000024609158,0.0000045374068,0.000009958881],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009785639,0.00031932868,0.0003882713,0.00016888705,0.00019635762,0.00039925973,0.00022239008,0.00027973024,0.00094493415],"category_scores_gemma":[0.00014217662,0.0001553173,0.0003514031,0.00010317539,0.00023638607,0.00023802483,0.00026705267,0.00035611205,0.00017763636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010952984,0.00016216408,0.0039473614,0.0005844361,0.00012509542,0.0005267904,0.000049839073,0.02459613,0.9403473,0.004022609,0.0010007623,0.02354212],"study_design_scores_gemma":[0.00037499788,0.0016367587,0.106500305,0.00012794996,0.0005075895,0.0021722203,0.00022035153,0.35082638,0.5133028,0.008248888,0.015925402,0.00015633476],"about_ca_topic_score_codex":0.0006528218,"about_ca_topic_score_gemma":0.00086934585,"teacher_disagreement_score":0.00094493415,"about_ca_system_score_codex":0.00029005547,"about_ca_system_score_gemma":0.0002852521,"threshold_uncertainty_score":0.0031611323},"labels":[],"label_agreement":null},{"id":"W4280608996","doi":"10.1172/jci148333","title":"HDAC6 modulates myofibril stiffness and diastolic function of the heart","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; National Institute on Aging; American Heart Association; Canadian Institutes of Health Research; Anschutz Medical Campus, University of Colorado; National Center for Advancing Translational Sciences; Italfarmaco; Small Business Innovation Research; Novo Nordisk; National Institutes of Health; Eikonizo Therapeutics; Novo Nordisk Fonden; Boettcher Foundation","keywords":"Titin; Myofibril; Sarcomere; HDAC6; Obscurin; Diastole; Internal medicine; Cardiomyopathy; Myofilament; Myocyte; Chemistry; Histone deacetylase; Cell biology; Heart failure; Medicine; Biology; Biochemistry; Histone","score_opus":0.04543004352491622,"score_gpt":0.34697587371279265,"score_spread":0.30154583018787645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280608996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98713255,0.007494275,0.0016039857,0.00026857207,0.00010037144,0.000022726463,0.00041700565,0.000086847605,0.0028737697],"genre_scores_gemma":[0.9934896,0.0025392442,0.00065837556,0.00006584599,0.000031582287,0.000011426724,0.00030947354,0.000011670934,0.0028828038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999294,0.00001039918,0.0000070197616,0.00001530176,0.000014702725,0.000023163677],"domain_scores_gemma":[0.999956,0.000003752587,0.000012867801,0.000004451584,0.0000066499797,0.000016234606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119984776,0.00024554922,0.00018893449,0.00013065587,0.00011712634,0.00026207685,0.00018100289,0.00017504317,0.0012354278],"category_scores_gemma":[0.00009384715,0.00010938794,0.00018799539,0.000091095884,0.00017646022,0.00013531419,0.00011441474,0.00032830308,0.00028442845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029860856,0.00003580435,0.0008186597,0.000043205222,0.000012747444,0.00002305417,0.000008852653,0.00003876139,0.9953768,0.00007715677,0.00009202656,0.003174281],"study_design_scores_gemma":[0.00013091468,0.0009105098,0.051811464,0.000013442057,0.00008591475,0.00033174254,0.000061380015,0.0012544022,0.9390145,0.00012136067,0.0062552136,0.000009053362],"about_ca_topic_score_codex":0.00040769065,"about_ca_topic_score_gemma":0.0014351255,"teacher_disagreement_score":0.0012354278,"about_ca_system_score_codex":0.0002232954,"about_ca_system_score_gemma":0.00014361081,"threshold_uncertainty_score":0.0041329265},"labels":[],"label_agreement":null},{"id":"W4281692879","doi":"10.1172/jci156243","title":"α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive individuals","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Vanderbilt Diabetes Research and Training Center, Vanderbilt University Medical Center; University of Pennsylvania; National Institutes of Health; Vanderbilt University","keywords":"Autoantibody; Glutamate decarboxylase; Islet; Medicine; Cell; Internal medicine; Diabetes mellitus; Endocrinology; Immunology; Biology; Antibody; Biochemistry; Enzyme","score_opus":0.015621731584301628,"score_gpt":0.2915426766168644,"score_spread":0.27592094503256276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281692879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977609,0.00087695784,0.00039100007,0.000035432553,0.000027424032,0.000014067682,0.00046949415,0.000016569506,0.0004081443],"genre_scores_gemma":[0.99757534,0.00059395237,0.0005638755,0.000090937814,0.000022514203,0.000021078955,0.0006951981,0.0000137335755,0.0004233761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998486,0.0000163369,0.000019960802,0.00006729664,0.000026692325,0.000021172515],"domain_scores_gemma":[0.9998266,0.000020304647,0.000056499677,0.000022417315,0.000019525003,0.000054619548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026076508,0.00036238032,0.00020598895,0.0006956062,0.00048807668,0.00058493164,0.00017332932,0.00027432284,0.0018497373],"category_scores_gemma":[0.0003438224,0.0001795718,0.00021834322,0.00041402888,0.00022391793,0.00015986359,0.00028847082,0.00037360878,0.00035863608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042277924,0.00026392762,0.43128318,0.00035256054,0.00023483645,0.004653371,0.0009982444,0.00032621386,0.5216049,0.00020571028,0.0011004249,0.034748826],"study_design_scores_gemma":[0.00008792776,0.0009980396,0.93844426,0.000056303823,0.00023531832,0.015021938,0.00053144223,0.00039587723,0.03935761,0.0003467936,0.0044970675,0.00002741641],"about_ca_topic_score_codex":0.0004055015,"about_ca_topic_score_gemma":0.00046894452,"teacher_disagreement_score":0.0018497373,"about_ca_system_score_codex":0.0001586034,"about_ca_system_score_gemma":0.000085402186,"threshold_uncertainty_score":0.0061879754},"labels":[],"label_agreement":null},{"id":"W4282034534","doi":"10.1172/jci160852","title":"Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Institute of Allergy and Infectious Diseases; Hirshberg Foundation for Pancreatic Cancer Research; National Cancer Institute; National Institutes of Health; Bristol-Myers Squibb; W. M. Keck Foundation","keywords":"Purine nucleoside phosphorylase; Autoimmunity; Biology; Immune system; TLR7; Cell biology; Immunology; Purine; Biochemistry; Innate immune system; Toll-like receptor; Enzyme","score_opus":0.04301281058107912,"score_gpt":0.32551379596429747,"score_spread":0.28250098538321833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282034534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959352,0.0010114253,0.0016442898,0.00010418871,0.000021478647,0.00002098844,0.00009190387,0.000102511614,0.0010678909],"genre_scores_gemma":[0.99778545,0.0002930423,0.00091887155,0.000030452213,0.00000757111,0.000016675363,0.000113647206,0.000012415452,0.0008217896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998486,0.00003270334,0.000013239947,0.000027513957,0.000030884457,0.00004702751],"domain_scores_gemma":[0.9998814,0.00001679901,0.000034053945,0.000013718014,0.000008252199,0.000045811437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017307367,0.00027239913,0.00021751663,0.00019384998,0.00010272441,0.00028678245,0.00020597894,0.00031198253,0.0010151124],"category_scores_gemma":[0.00015425964,0.000115054216,0.00014199656,0.00007525445,0.0003056,0.00019118997,0.00026438653,0.0005786008,0.00021964614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036894227,0.00007041158,0.0003020555,0.000029834931,0.0000054600387,0.00007970547,0.000008592493,0.0000735566,0.9964574,0.00022015638,0.000042702504,0.0023411443],"study_design_scores_gemma":[0.000047328234,0.0009043138,0.0021478846,0.0000064869837,0.000014105171,0.00044626417,0.000016336122,0.0006037769,0.9943798,0.00009137985,0.0013392968,0.0000030218066],"about_ca_topic_score_codex":0.00013127542,"about_ca_topic_score_gemma":0.00029178953,"teacher_disagreement_score":0.0010151124,"about_ca_system_score_codex":0.00014058771,"about_ca_system_score_gemma":0.00018155239,"threshold_uncertainty_score":0.003395915},"labels":[],"label_agreement":null},{"id":"W4282821976","doi":"10.1172/jci155914","title":"Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto; Hospital for Sick Children; Université Laval; National Heart, Lung, and Blood Institute; National Cancer Institute; Cincinnati Children's Hospital Medical Center","keywords":"Paracrine signalling; Cell biology; Stem cell; Wnt signaling pathway; Biology; Haematopoiesis; Stromal cell; Downregulation and upregulation; WNT5A; Regeneration (biology); Hematopoietic stem cell; Cancer research; Immunology; Signal transduction; Genetics; Gene","score_opus":0.08673644633285822,"score_gpt":0.34543711336943894,"score_spread":0.25870066703658073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282821976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9684152,0.014642028,0.011238703,0.00036340838,0.000055820852,0.00006136255,0.001140333,0.000372398,0.0037106895],"genre_scores_gemma":[0.9882323,0.0038708106,0.0032184375,0.00007510678,0.000019374744,0.000031024447,0.0005590489,0.000018586667,0.003975379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998629,0.000020459258,0.000012325568,0.000032286538,0.000043820455,0.000028197475],"domain_scores_gemma":[0.9999374,0.0000033785782,0.000027244057,0.000004157645,0.000007855414,0.000019866251],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014362972,0.00034580776,0.00018488555,0.00033392536,0.00013993331,0.000350129,0.0001405892,0.00015527733,0.0011074641],"category_scores_gemma":[0.00006896888,0.00014183593,0.00025368406,0.00013338287,0.00022665145,0.0002479985,0.00027488152,0.0004399612,0.00022859775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012609626,0.0000076110696,0.0011880788,0.00009417272,0.000011210949,0.00012141311,0.000023902418,0.00010972622,0.99332386,0.00041839716,0.00008800175,0.0044875606],"study_design_scores_gemma":[0.00002445844,0.00026046715,0.02663211,0.00002464141,0.00006549452,0.0006476282,0.00007862656,0.0016194351,0.9556665,0.00017188645,0.014798672,0.000010160831],"about_ca_topic_score_codex":0.0008837108,"about_ca_topic_score_gemma":0.0015611559,"teacher_disagreement_score":0.0011074641,"about_ca_system_score_codex":0.00034033525,"about_ca_system_score_gemma":0.0002721437,"threshold_uncertainty_score":0.0037047863},"labels":[],"label_agreement":null},{"id":"W4282836213","doi":"10.1172/jci157086","title":"Disrupting the DREAM complex enables proliferation of adult human pancreatic β cells","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health","keywords":"DYRK1A; Cell biology; Biology; Kinase; Cell growth; Biochemistry","score_opus":0.10252609596712822,"score_gpt":0.376283097642585,"score_spread":0.2737570016754568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282836213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890246,0.0031210172,0.004036128,0.0002707332,0.0000670297,0.000041853968,0.00078556215,0.00015193797,0.002501145],"genre_scores_gemma":[0.9916152,0.0013458102,0.0031958737,0.00009863324,0.000009991211,0.000028594812,0.00096973625,0.000026698424,0.0027094889],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988246,0.00002023808,0.000018864144,0.000031073017,0.00002397032,0.000023367133],"domain_scores_gemma":[0.9999294,0.000017148408,0.000017718205,0.00001188682,0.000004970328,0.000018809089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017127176,0.00014942492,0.00016200625,0.00012112041,0.000110269015,0.0003696989,0.00014701778,0.00013418823,0.0013280584],"category_scores_gemma":[0.00014926557,0.00011174832,0.00016332262,0.000080855534,0.00013001123,0.00013357608,0.00019897528,0.0004171382,0.000367289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014823138,0.000027404152,0.00019044997,0.000037714683,0.000005740608,0.000037578404,0.000012752212,0.000044891513,0.99754363,0.00009830253,0.0000877111,0.0017656283],"study_design_scores_gemma":[0.000014947499,0.00026125362,0.0016516296,0.0000036772037,0.000010647813,0.00019038787,0.000022421997,0.00044249286,0.99328136,0.000033475397,0.004085186,0.000002450139],"about_ca_topic_score_codex":0.00036359028,"about_ca_topic_score_gemma":0.00045384624,"teacher_disagreement_score":0.0013280584,"about_ca_system_score_codex":0.00015328181,"about_ca_system_score_gemma":0.00015803879,"threshold_uncertainty_score":0.0044427514},"labels":[],"label_agreement":null},{"id":"W4282946071","doi":"10.1172/jci154317","title":"The neuronal tyrosine kinase receptor ligand ALKAL2 mediates persistent pain","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary; Alberta Children's Hospital","funders":"Alberta Children's Hospital Research Institute; Canada Research Chairs; Crohn's and Colitis Canada; Canadian Institutes of Health Research; Agence de la Biomédecine; University of Calgary","keywords":"Receptor tyrosine kinase; Tyrosine kinase; ROR1; Tropomyosin receptor kinase C; Receptor; Receptor Protein-Tyrosine Kinases; Ligand (biochemistry); Medicine; Chemistry; Cell biology; Biology; Internal medicine; Platelet-derived growth factor receptor","score_opus":0.07057905906645386,"score_gpt":0.3428778714697414,"score_spread":0.27229881240328757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282946071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9499901,0.031844184,0.0043596905,0.0011616282,0.00018084931,0.0000715555,0.000775719,0.0001883353,0.011427887],"genre_scores_gemma":[0.9904107,0.0057703014,0.00048354268,0.00014681692,0.000034242817,0.000021017348,0.00030588126,0.000008502668,0.0028190434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992394,0.000014374952,0.0000048149186,0.000014341254,0.000017301132,0.000025298721],"domain_scores_gemma":[0.9999621,0.0000043662335,0.000011954522,0.000003075828,0.0000061438795,0.000012388923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095690084,0.00039106866,0.00023666798,0.000121289966,0.00019551766,0.00043817674,0.00018376512,0.00028270468,0.0022798488],"category_scores_gemma":[0.0001008952,0.00008856392,0.00019929862,0.00012561247,0.00021424188,0.00031580884,0.0003175436,0.00062878523,0.0006138126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005456813,0.000066248605,0.0013213683,0.0003127231,0.00003257323,0.0005939866,0.000035854784,0.00018863835,0.987288,0.0005502961,0.0006712955,0.008393259],"study_design_scores_gemma":[0.00033102714,0.0029019658,0.06482021,0.00014923979,0.0002571481,0.008085666,0.0005499416,0.005106488,0.8667729,0.0016272423,0.049344193,0.000053901833],"about_ca_topic_score_codex":0.00046469734,"about_ca_topic_score_gemma":0.00093534036,"teacher_disagreement_score":0.0022798488,"about_ca_system_score_codex":0.00035264698,"about_ca_system_score_gemma":0.00024059195,"threshold_uncertainty_score":0.0076268315},"labels":[],"label_agreement":null},{"id":"W4283715614","doi":"10.1172/jci151666","title":"Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Provincial Health Services Authority; Maze Therapeutics; BeiGene; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; National Human Genome Research Institute; Agios Pharmaceuticals; Foghorn Therapeutics; Parker Institute for Cancer Immunotherapy; Leukemia and Lymphoma Society; G. Harold and Leila Y. Mathers Foundation; BC Children’s Hospital Foundation; BC Children's Hospital; Howard Hughes Medical Institute; Biogen; Dana-Farber/Harvard Cancer Center; Children's Hospital Foundation; Conquer Cancer Foundation; National Heart, Lung, and Blood Institute; Pfizer; Cancer Research Institute","keywords":"Psychological repression; Merkel cell carcinoma; Epigenetics; Human leukocyte antigen; Biology; Carcinoma; Cancer research; Merkel cell; Virology; Immunology; Genetics; Antigen; Gene","score_opus":0.052087356600831226,"score_gpt":0.35607881277838294,"score_spread":0.3039914561775517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283715614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968694,0.0010704446,0.0007396145,0.00006612887,0.000011314439,0.000022264083,0.00015648144,0.00006492767,0.0009994585],"genre_scores_gemma":[0.9981635,0.00033252317,0.0005291896,0.000024738387,0.0000030566787,0.000011108348,0.00015677711,0.000007541983,0.00077159156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990535,0.000015433188,0.000010638227,0.000016175722,0.00003193677,0.000020441012],"domain_scores_gemma":[0.9999105,0.000023271179,0.000019666017,0.000016921507,0.000007007321,0.000022581802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013159287,0.00015560148,0.00021814347,0.00022291335,0.0001392392,0.00028040152,0.0001685195,0.00018973822,0.0011546292],"category_scores_gemma":[0.00017813197,0.000094979085,0.00014670576,0.00013604152,0.00017559584,0.00012316863,0.00015339468,0.00039398065,0.0002348806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006338116,0.000038648064,0.0006151939,0.000028859047,0.0000038666185,0.00013529774,0.000010603364,0.00007653697,0.9963929,0.00009899623,0.000044673983,0.0024908537],"study_design_scores_gemma":[0.000026843845,0.00073221314,0.013331032,0.000004533871,0.000013906669,0.0014201322,0.000047089285,0.00093625183,0.9810415,0.000055922093,0.0023861516,0.000004335113],"about_ca_topic_score_codex":0.00039986992,"about_ca_topic_score_gemma":0.0010995305,"teacher_disagreement_score":0.0011546292,"about_ca_system_score_codex":0.00021957453,"about_ca_system_score_gemma":0.0001796886,"threshold_uncertainty_score":0.0038626194},"labels":[],"label_agreement":null},{"id":"W4283726838","doi":"10.1172/jci161070","title":"TGF-β1–induced endothelial-mesenchymal transition: a potential contributor to fibrotic remodeling in atrial fibrillation?","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsche Forschungsgemeinschaft; European Commission","keywords":"Atrial fibrillation; Fibrosis; Cardiac fibrosis; Epithelial–mesenchymal transition; Mesenchymal stem cell; Transforming growth factor; Medicine; Myofibroblast; Cardiology; Internal medicine; Function (biology); Heart failure; Transition (genetics); Regulator; Pathology; Biology; Cell biology","score_opus":0.07343482893537602,"score_gpt":0.3604289174561574,"score_spread":0.2869940885207814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283726838","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004046774,0.013948547,0.0004289429,0.9381507,0.039768457,0.000020200194,0.00004040318,0.000039972172,0.0035559414],"genre_scores_gemma":[0.04904224,0.025094388,0.00090422947,0.56354994,0.351853,0.00006190671,0.000052677715,0.000026121239,0.009415502],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99930227,0.00021153248,0.00009935851,0.00008776239,0.00019813768,0.00010100195],"domain_scores_gemma":[0.9977393,0.0011576863,0.00024169029,0.0000981793,0.0004616518,0.00030150957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010173043,0.00041945252,0.0008486224,0.00039225226,0.0011385113,0.0014938832,0.00079371023,0.012788082,0.0024722985],"category_scores_gemma":[0.005167229,0.00029998305,0.00065553765,0.00031881552,0.0018122292,0.0019145465,0.00050351914,0.012056966,0.0022866563],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060621015,0.00026002337,0.0058653452,0.0005006808,0.000069282025,0.047679916,0.0005113738,0.00025427408,0.0042493544,0.012023022,0.84207314,0.085907385],"study_design_scores_gemma":[0.0005623105,0.000509468,0.00722238,0.0006765337,0.00013043768,0.070375614,0.0011737964,0.0022429551,0.0033239746,0.026258655,0.88738626,0.00013766799],"about_ca_topic_score_codex":0.00062565727,"about_ca_topic_score_gemma":0.00086743245,"teacher_disagreement_score":0.012788082,"about_ca_system_score_codex":0.0012693675,"about_ca_system_score_gemma":0.0009660448,"threshold_uncertainty_score":0.0092099905},"labels":[],"label_agreement":null},{"id":"W4285385793","doi":"10.1172/jci161979","title":"Genetic mechanism for the loss of PRAME in B cell lymphomas. Reply.","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Spinal Cord Injury BC","funders":"","keywords":"Mechanism (biology); Biology; Cancer research; Lymphoma; Computational biology; Genetics; Immunology; Epistemology; Philosophy","score_opus":0.07895625948709005,"score_gpt":0.35606782101422313,"score_spread":0.27711156152713307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285385793","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0015476731,0.011217954,0.00062876625,0.93898803,0.04677111,0.000028607783,0.00021321987,0.00009703868,0.00050758396],"genre_scores_gemma":[0.016798927,0.010465385,0.0013944268,0.8134381,0.1533111,0.000094233656,0.00014661963,0.000050466006,0.0043007997],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99877197,0.00031791156,0.00026168258,0.0002435303,0.00026200444,0.00014279905],"domain_scores_gemma":[0.9934521,0.0035859777,0.00057222554,0.00028322896,0.0016693951,0.0004370888],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035427238,0.000950542,0.0012444705,0.00082480157,0.00088338077,0.0011647104,0.0022991376,0.013185246,0.0029740315],"category_scores_gemma":[0.016403986,0.00057969015,0.0011010891,0.00056536647,0.0016142934,0.0039796326,0.0013702869,0.017138314,0.0023283437],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026692802,0.000048851336,0.004613095,0.0004504615,0.00007299626,0.004318693,0.00027532637,0.00022211336,0.00095700694,0.0018880283,0.96399397,0.022892471],"study_design_scores_gemma":[0.00022820737,0.00030371215,0.02047836,0.00068162626,0.00019870403,0.02192025,0.0011021477,0.0013445045,0.0021862336,0.013499657,0.93770975,0.00034683265],"about_ca_topic_score_codex":0.0028944404,"about_ca_topic_score_gemma":0.0025590446,"teacher_disagreement_score":0.013185246,"about_ca_system_score_codex":0.0014909918,"about_ca_system_score_gemma":0.0011090582,"threshold_uncertainty_score":0.018735945},"labels":[],"label_agreement":null},{"id":"W4285388603","doi":"10.1172/jci159876","title":"Frequent detection but lack of infectivity of SARS-CoV-2 RNA in presymptomatic, infected blood donor plasma","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Institutes of Health; Grifols; U.S. Department of Health and Human Services","keywords":"Viremia; Infectivity; Medicine; Population; Virology; Virus; Immunology; Whole blood","score_opus":0.1603804722911355,"score_gpt":0.4321814778785529,"score_spread":0.2718010055874174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285388603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976338,0.00033384323,0.0007294536,0.00003517635,0.000010312626,0.000026605223,0.000309983,0.000027599439,0.0008931731],"genre_scores_gemma":[0.99865544,0.0001297269,0.00041889027,0.000053416807,0.000014481865,0.000015097367,0.0004080523,0.0000030739336,0.00030175102],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99960333,0.00006415404,0.00004214609,0.0001257307,0.00010538568,0.000059317113],"domain_scores_gemma":[0.999331,0.00019947512,0.00021417627,0.00006354187,0.000106499814,0.0000853678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043524726,0.00020461476,0.00022212454,0.00051353365,0.00029022145,0.0005316875,0.00017146884,0.00044180703,0.0013730216],"category_scores_gemma":[0.0010743011,0.00020321392,0.00012377769,0.00029396106,0.000286454,0.00022837186,0.0002031926,0.00036682465,0.00044861124],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008176815,0.00024316533,0.61704695,0.00012133878,0.00006260279,0.0019447578,0.00066112995,0.00016347221,0.36634758,0.00025326462,0.0005824444,0.011755635],"study_design_scores_gemma":[0.000017479293,0.00086948334,0.9014753,0.00001962197,0.000049702303,0.015467773,0.00067751703,0.000544562,0.07938107,0.00021971363,0.0012608607,0.000016829224],"about_ca_topic_score_codex":0.0006595574,"about_ca_topic_score_gemma":0.00036863884,"teacher_disagreement_score":0.0013730216,"about_ca_system_score_codex":0.00015920159,"about_ca_system_score_gemma":0.00014982269,"threshold_uncertainty_score":0.0045931935},"labels":[],"label_agreement":null},{"id":"W4288434347","doi":"10.1172/jci154571","title":"Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; McGill University; Georgetown University; National Institutes of Health; Cystic Fibrosis Foundation","keywords":"Cystic fibrosis; ΔF508; Nonsense mutation; Cell biology; Cell culture; Mutation; Biology; Telomerase reverse transcriptase; Cystic fibrosis transmembrane conductance regulator; Cancer research; Molecular biology; Chemistry; Genetics; Gene; Telomerase; Missense mutation","score_opus":0.09750121278110492,"score_gpt":0.41086115391218375,"score_spread":0.31335994113107885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288434347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98809916,0.0030368688,0.004802239,0.00029717287,0.00006383231,0.00012932818,0.00071525446,0.00037896022,0.0024770924],"genre_scores_gemma":[0.9906843,0.0016217271,0.003458317,0.00010625195,0.000017274946,0.00006831005,0.0009698317,0.000037835434,0.003036364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998653,0.000023327188,0.000018111286,0.000018991692,0.00004103915,0.000033228782],"domain_scores_gemma":[0.9999062,0.000016403037,0.000021573522,0.00001478881,0.000014330964,0.000026731821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028956364,0.00030152051,0.00036158055,0.00020435915,0.00012066079,0.00032979192,0.000234348,0.0003695535,0.0011465831],"category_scores_gemma":[0.00017723082,0.0001062031,0.00027521822,0.0001221775,0.00017940065,0.00016309167,0.00016555282,0.00070979755,0.00051077205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017289011,0.00009562223,0.00026880827,0.000052215037,0.0000074585982,0.00016708173,0.000016366102,0.00011220322,0.99390924,0.0000850056,0.0002308749,0.0048823226],"study_design_scores_gemma":[0.00012867257,0.0012932096,0.004868712,0.000010449704,0.00002386028,0.0012864897,0.00003862379,0.0010567731,0.9848177,0.000055859804,0.006410827,0.000008869884],"about_ca_topic_score_codex":0.0002976413,"about_ca_topic_score_gemma":0.00075664086,"teacher_disagreement_score":0.0011465831,"about_ca_system_score_codex":0.00019176543,"about_ca_system_score_gemma":0.00019226526,"threshold_uncertainty_score":0.0038357377},"labels":[],"label_agreement":null},{"id":"W4288447650","doi":"10.1172/jci161908","title":"SPTLC1 variants associated with ALS produce distinct sphingolipid signatures through impaired interaction with ORMDL proteins","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Stiftung für die Erforschung der Muskelkrankheiten; National Science Foundation","keywords":"Sphingolipid; Biology; Serine; Phenotype; HEK 293 cells; Transmembrane protein; Protein subunit; Cell biology; Genetics; Molecular biology; Gene; Phosphorylation; Receptor","score_opus":0.09747993868324506,"score_gpt":0.39382650525099827,"score_spread":0.2963465665677532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288447650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99855536,0.0002484521,0.00029804528,0.000054824744,0.0000071174127,0.000009562412,0.0002252574,0.00003237348,0.00056894927],"genre_scores_gemma":[0.9987425,0.00012255789,0.0003643318,0.000042139043,0.0000073332694,0.0000061376795,0.00039504832,0.000012863222,0.00030710283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975127,0.000034892593,0.000031486838,0.00007820375,0.00007007345,0.000034126817],"domain_scores_gemma":[0.99971014,0.00005138827,0.00011308961,0.000021227439,0.000030535753,0.00007363572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016445525,0.0007519987,0.00033621446,0.0005679365,0.00028656077,0.00035455768,0.00025302317,0.0006558169,0.0017652839],"category_scores_gemma":[0.00050165196,0.00016193042,0.00020804489,0.00047744543,0.00046355507,0.00014625155,0.00042555708,0.0005013869,0.0004351261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013938819,0.00012366674,0.08090567,0.000108413835,0.00009408591,0.01418302,0.00026672843,0.00030339402,0.89323336,0.00021470322,0.00053987757,0.008633252],"study_design_scores_gemma":[0.00017356043,0.0010433388,0.6541673,0.000059638758,0.00016152546,0.11488274,0.00031911282,0.0029756702,0.22121355,0.00037202955,0.004587111,0.000044502605],"about_ca_topic_score_codex":0.0010143651,"about_ca_topic_score_gemma":0.00079108065,"teacher_disagreement_score":0.0017652839,"about_ca_system_score_codex":0.00031796863,"about_ca_system_score_gemma":0.00014721781,"threshold_uncertainty_score":0.0059054494},"labels":[],"label_agreement":null},{"id":"W4292065316","doi":"10.1172/jci159283","title":"HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Government of Ontario; Terry Fox Research Institute; Canadian Cancer Society; Ontario Institute for Cancer Research","keywords":"Epitope; Immunity; Tumor microenvironment; Inflammation; Cancer research; Immunology; Immune system; Cell biology; Biology; Chemistry; Antigen","score_opus":0.0292737729577458,"score_gpt":0.34655608990629405,"score_spread":0.31728231694854825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292065316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909338,0.0027920287,0.0029360156,0.0001631136,0.00006791855,0.0000668117,0.00023678405,0.00013030173,0.0026731896],"genre_scores_gemma":[0.99685717,0.0006551838,0.00095021527,0.000035023284,0.000014916314,0.000016988306,0.00010476123,0.000007684098,0.001357883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991953,0.000012124811,0.000005345885,0.000013817776,0.0000202955,0.00002894636],"domain_scores_gemma":[0.9999653,0.000004057041,0.000008920678,0.0000033262813,0.000004036055,0.000014274562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012334257,0.0003557478,0.00019499953,0.0001995186,0.00009151651,0.00027762278,0.0001400517,0.000116718504,0.0014914059],"category_scores_gemma":[0.000055397988,0.00009343808,0.00019515856,0.00010913965,0.00019669547,0.00013531999,0.00013375017,0.00050231564,0.00030473588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023129632,0.00008673546,0.00025419897,0.00003997961,0.000006210571,0.000024875473,0.00000767236,0.000118160075,0.9955289,0.000107231244,0.00007128068,0.0035235216],"study_design_scores_gemma":[0.000050853054,0.00088461436,0.003632402,0.000004457161,0.00002078502,0.00011589006,0.000023945231,0.0011469512,0.9919688,0.000038518796,0.0021094766,0.0000032452924],"about_ca_topic_score_codex":0.0005006486,"about_ca_topic_score_gemma":0.0013994684,"teacher_disagreement_score":0.0014914059,"about_ca_system_score_codex":0.00031027754,"about_ca_system_score_gemma":0.00027107808,"threshold_uncertainty_score":0.004989207},"labels":[],"label_agreement":null},{"id":"W4293582093","doi":"10.1172/jci157074","title":"Predicting cognitive decline in Parkinson’s disease using FDG-PET–based supervised learning","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Health Sciences Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Max Rady College of Medicine, University of Manitoba; University of Manitoba; Manitoba Medical Service Foundation","keywords":"Parkinson's disease; Cognitive decline; Disease; Cognition; Medicine; Positron emission tomography; Psychology; Machine learning; Neuroscience; Internal medicine; Computer science; Dementia; Nuclear medicine","score_opus":0.11170715323788596,"score_gpt":0.4238099032803553,"score_spread":0.31210275004246935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293582093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9731155,0.00046998254,0.025203366,0.00016844308,0.000026724178,0.00005427495,0.00026492786,0.00022355189,0.00047328506],"genre_scores_gemma":[0.9947536,0.000052082814,0.0046496163,0.000024303476,0.00001509043,0.000020025842,0.00036808423,0.0000045261704,0.00011263801],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99958616,0.00017652013,0.000041361076,0.000086965214,0.000059054535,0.000049961305],"domain_scores_gemma":[0.99820447,0.0011004076,0.00021753398,0.000091522306,0.0002777368,0.00010831468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015968486,0.00056079973,0.00053679396,0.0008857711,0.00018009942,0.00049962883,0.00044308812,0.0005385451,0.00038018994],"category_scores_gemma":[0.0030471657,0.00014666967,0.0005044482,0.00024228758,0.00021683105,0.00031251065,0.00030176726,0.00045548542,0.000130785],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018517427,0.0012431188,0.45210794,0.00013287872,0.00054131617,0.00041898983,0.00014118491,0.28897476,0.004953954,0.00032846798,0.003008355,0.24629721],"study_design_scores_gemma":[0.000033998,0.00027121408,0.025610384,0.000012688566,0.000033954908,0.0001181118,0.000026381009,0.97171706,0.0012501503,0.0007537782,0.00016045888,0.000011864052],"about_ca_topic_score_codex":0.0028857053,"about_ca_topic_score_gemma":0.0028124296,"teacher_disagreement_score":0.0028857053,"about_ca_system_score_codex":0.0004740181,"about_ca_system_score_gemma":0.0003879644,"threshold_uncertainty_score":0.008445084},"labels":[],"label_agreement":null},{"id":"W4295423187","doi":"10.1172/jci159579","title":"Immune dysfunction signatures predict outcomes and define checkpoint blockade–unresponsive microenvironments in acute myeloid leukemia","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute; Huntsman Cancer Foundation; Genentech; National Institutes of Health; Technische Universität Dresden; Fonds National de la Recherche Luxembourg; Johns Hopkins University; American Society for Transplantation and Cellular Therapy; Qatar National Research Fund; American Society of Clinical Oncology; Huntsman Cancer Institute; National Heart, Lung, and Blood Institute; John and Lucille Van Geest Foundation; Gabrielle's Angel Foundation for Cancer Research; American Association for Cancer Research; St. Baldrick's Foundation; Trent University; Ladies Leukemia League; Leukemia and Lymphoma Society; Stand Up To Cancer; Entertainment Industry Foundation; U.S. Department of Defense; Rally Foundation; Children's Hospital of Philadelphia; Nottingham Trent University; Conquer Cancer Foundation","keywords":"Myeloid leukemia; Medicine; Immune checkpoint; Blockade; Immunotherapy; Oncology; CD8; Immune system; Leukemia; Effector; Internal medicine; Immunology; Cancer research; Receptor","score_opus":0.030171004445256167,"score_gpt":0.3197234006004307,"score_spread":0.28955239615517453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295423187","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977399,0.00062422577,0.00053426024,0.00007272909,0.000005453329,0.000017433387,0.00063220557,0.000012470123,0.00036139338],"genre_scores_gemma":[0.9979978,0.00019966683,0.0006446978,0.0000905173,0.000011847294,0.000028862089,0.00082066236,0.000005864606,0.00020000739],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99982053,0.000036889178,0.000017460363,0.00004870073,0.000036830686,0.000039663064],"domain_scores_gemma":[0.9996257,0.00007644437,0.00018692193,0.000020968999,0.000040502462,0.000049401777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046748956,0.00023057617,0.0003369936,0.0006144664,0.00014670326,0.00051478384,0.00018196675,0.00023682056,0.0010302204],"category_scores_gemma":[0.00063148263,0.000105834,0.00019206919,0.0005387474,0.00023397917,0.00018526126,0.00038501993,0.00039297497,0.00019434319],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020723888,0.00017151677,0.92533624,0.00012250623,0.00014131788,0.00010042809,0.00011867373,0.001543696,0.038022175,0.00015560912,0.0008206369,0.03139485],"study_design_scores_gemma":[0.000052475,0.00045175166,0.98373574,0.00002343821,0.00011462184,0.00029678745,0.00018174012,0.004501995,0.008035829,0.00066885527,0.001924825,0.0000118682265],"about_ca_topic_score_codex":0.00035975978,"about_ca_topic_score_gemma":0.0007216319,"teacher_disagreement_score":0.0010302204,"about_ca_system_score_codex":0.0002787872,"about_ca_system_score_gemma":0.00018024424,"threshold_uncertainty_score":0.0034464002},"labels":[],"label_agreement":null},{"id":"W4295787604","doi":"10.1172/jci160565","title":"Durability of protection and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) COVID-19 vaccine over 6 months","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada)","funders":"National Institutes of Health; AstraZeneca; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation; Pfizer; Gilead Sciences; BioFire Diagnostics; Sanofi","keywords":"Medicine; Vaccination; Placebo; Incidence (geometry); Clinical endpoint; Immunogenicity; Coronavirus disease 2019 (COVID-19); Randomized controlled trial; Internal medicine; Vaccine efficacy; Immunology; Antibody; Disease; Infectious disease (medical specialty); Pathology","score_opus":0.14637918739366124,"score_gpt":0.44182263025039664,"score_spread":0.2954434428567354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295787604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960802,0.0022223303,0.00028183308,0.00007200645,0.000023346438,0.000046149176,0.000579014,0.000015559126,0.0006794655],"genre_scores_gemma":[0.99851316,0.0002538113,0.000117514755,0.000053315463,0.000027065458,0.000037010326,0.000591072,0.000003499991,0.0004035766],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99931526,0.0001958978,0.000057530608,0.00012275385,0.0001624485,0.00014611814],"domain_scores_gemma":[0.9986123,0.00028032475,0.00061367976,0.0001236343,0.00015830465,0.00021171891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028429015,0.00027411524,0.0006289791,0.0002435468,0.0001977231,0.00034658748,0.00022965929,0.0002955615,0.002206761],"category_scores_gemma":[0.0018388175,0.00015109235,0.00048020636,0.00016244309,0.00019585855,0.00050285197,0.00017031355,0.0006512474,0.00031224467],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.193305,0.0077031297,0.34701657,0.00093720824,0.0021564558,0.0003568687,0.00047830289,0.002962842,0.14093852,0.000246205,0.0036892083,0.30020964],"study_design_scores_gemma":[0.005562782,0.12424139,0.82817864,0.00006473672,0.0010197923,0.0008308639,0.000112383226,0.0015477672,0.033508457,0.00019699414,0.0046909936,0.000045267792],"about_ca_topic_score_codex":0.00037624815,"about_ca_topic_score_gemma":0.00042473784,"teacher_disagreement_score":0.0028429015,"about_ca_system_score_codex":0.00023649247,"about_ca_system_score_gemma":0.00021236086,"threshold_uncertainty_score":0.015034914},"labels":[],"label_agreement":null},{"id":"W4295907188","doi":"10.1172/jci152961","title":"Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Biomedical Research Council; National Medical Research Council; Medical Research Council; Public Health England","keywords":"Internal medicine; Insulin; Endocrinology; Insulin resistance; Insulin receptor; Biology; Chemistry; Medicine","score_opus":0.045259975679720725,"score_gpt":0.33021660335115244,"score_spread":0.2849566276714317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295907188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953243,0.0016462451,0.001285484,0.00015324035,0.000026914828,0.000011316861,0.00043807438,0.000057479927,0.0010569929],"genre_scores_gemma":[0.99811816,0.0003803468,0.00056328275,0.00006135519,0.000021430254,0.000009790118,0.00031637313,0.000021527472,0.00050779304],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99983084,0.00003135288,0.000016283413,0.00007560012,0.00003180543,0.000014066449],"domain_scores_gemma":[0.99982184,0.000026559395,0.00008339598,0.000017750355,0.000015868613,0.000034589473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015092058,0.0004662928,0.00033713435,0.0007921208,0.0003319438,0.00029928403,0.00012571683,0.0003526719,0.002983155],"category_scores_gemma":[0.0003405543,0.00016063891,0.00019793058,0.00052974554,0.00029764985,0.00009331503,0.00020185209,0.00030728834,0.0002950204],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042525236,0.00023297274,0.57592154,0.00018723599,0.0005714545,0.011353551,0.00036416785,0.00031796348,0.36302784,0.00074588857,0.0022972894,0.040727574],"study_design_scores_gemma":[0.00010300528,0.0005491035,0.94095224,0.000042439304,0.00030160183,0.03228312,0.00012493021,0.00079192745,0.017505363,0.0005602598,0.006761848,0.000024079814],"about_ca_topic_score_codex":0.00057004916,"about_ca_topic_score_gemma":0.00038436463,"teacher_disagreement_score":0.002983155,"about_ca_system_score_codex":0.00012004498,"about_ca_system_score_gemma":0.00006543562,"threshold_uncertainty_score":0.009979665},"labels":[],"label_agreement":null},{"id":"W4296685469","doi":"10.1172/jci146095","title":"Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thermo Fisher Scientific (Canada); Children's Hospital of Eastern Ontario; Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Texas Health Science Center at San Antonio; Ontario Institute for Regenerative Medicine; Fundação de Amparo à Pesquisa do Estado de São Paulo; Génome Québec; Ottawa Hospital Research Institute; McMaster University; Texas Biomedical Research Institute; Stem Cell Network; University of Ottawa","keywords":"Neurogenesis; Bronchopulmonary dysplasia; Hyperoxia; Neuroscience; Medicine; Neural stem cell; Population; Cognitive decline; Progenitor cell; Psychology; Stem cell; Pathology; Internal medicine; Biology; Disease; Lung; Gestational age; Pregnancy; Dementia","score_opus":0.09102071060534352,"score_gpt":0.4050582111634092,"score_spread":0.3140375005580657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296685469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875564,0.002795154,0.0048409947,0.00033792722,0.00009106179,0.000087808265,0.001926105,0.00026596867,0.002098608],"genre_scores_gemma":[0.97888374,0.00421269,0.005214843,0.0002591962,0.000035361136,0.0004075693,0.00224294,0.0000991218,0.008644555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99956805,0.000056887973,0.000062635525,0.00010927882,0.00009176943,0.000111340785],"domain_scores_gemma":[0.9996184,0.000041089595,0.00014596146,0.00004515328,0.000031457024,0.00011790114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034721039,0.0006529385,0.00036717748,0.0010838272,0.00033718353,0.00053259544,0.0005157364,0.00075029855,0.0026233916],"category_scores_gemma":[0.000185711,0.00035866548,0.00053753017,0.00029083499,0.0006613286,0.0003983376,0.0004920576,0.0015992083,0.00048388826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006918247,0.00022073732,0.00070941215,0.00007505748,0.00002755786,0.00024644172,0.00007179042,0.0001306231,0.9948815,0.00025873815,0.00013704193,0.0025494052],"study_design_scores_gemma":[0.0000737276,0.0014719641,0.021119103,0.00008023459,0.00007556689,0.00080434245,0.00024381778,0.0014382829,0.97105736,0.0003742165,0.0032394573,0.00002195302],"about_ca_topic_score_codex":0.0014981171,"about_ca_topic_score_gemma":0.00327125,"teacher_disagreement_score":0.0026233916,"about_ca_system_score_codex":0.0005161928,"about_ca_system_score_gemma":0.00054014236,"threshold_uncertainty_score":0.008776069},"labels":[],"label_agreement":null},{"id":"W4296687832","doi":"10.1172/jci160101","title":"Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Allergy and Infectious Diseases; National Institutes of Health; University of Texas Southwestern Medical Center; Jeffrey Modell Foundation","keywords":"Mesenchymal stem cell; Mesenchyme; Biology; Embryonic stem cell; Cell biology; Extracellular matrix; DiGeorge syndrome; Pathology; Immunology; Genetics; Medicine; Gene","score_opus":0.055268725461283176,"score_gpt":0.35187864918323086,"score_spread":0.29660992372194767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296687832","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781098,0.0055996105,0.008805401,0.0005440281,0.00044130834,0.00019926582,0.0027318315,0.0008037006,0.0027650828],"genre_scores_gemma":[0.97679317,0.0041054417,0.005798304,0.00040354376,0.00005799556,0.00028600288,0.003070513,0.0001935288,0.00929143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994899,0.00006910057,0.000053989534,0.00012118903,0.00016445485,0.0001013577],"domain_scores_gemma":[0.9996768,0.0000389875,0.00008744308,0.00003454902,0.00003638561,0.00012580137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038485942,0.00053808355,0.0005704464,0.0007003139,0.00027470494,0.0006146889,0.00039284126,0.0007838633,0.0020873006],"category_scores_gemma":[0.00028866425,0.00031980916,0.00057207496,0.0002051109,0.00043332405,0.0002889495,0.00048611453,0.0017743517,0.0005550023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035346032,0.0001578389,0.00046653178,0.0001951433,0.00003308146,0.00034591937,0.00006691905,0.0002898388,0.9929898,0.00035089918,0.0003258155,0.004424769],"study_design_scores_gemma":[0.00032172323,0.0024404114,0.011751146,0.00015853102,0.00027725985,0.0018517672,0.00032306713,0.003358585,0.94832736,0.00048025188,0.030662313,0.0000474542],"about_ca_topic_score_codex":0.00054009137,"about_ca_topic_score_gemma":0.0012286174,"teacher_disagreement_score":0.0020873006,"about_ca_system_score_codex":0.00026336734,"about_ca_system_score_gemma":0.00034057137,"threshold_uncertainty_score":0.006982684},"labels":[],"label_agreement":null},{"id":"W4300003374","doi":"10.1172/jci163553","title":"GIGYF1-disturbed IGF-1R recycling: a potential contributor to autism spectrum disorder pathogenesis?","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Institute of Aging","funders":"China Postdoctoral Science Foundation","keywords":"Autism spectrum disorder; Pathogenesis; Autism; Neurodevelopmental disorder; Disease; Neuroscience; Psychology; Genetics; Medicine; Biology; Psychiatry; Immunology; Pathology","score_opus":0.028471252196197123,"score_gpt":0.30568361349643397,"score_spread":0.27721236130023685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4300003374","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0026884044,0.0024511921,0.00028508747,0.9597058,0.030554496,0.000022695032,0.000075702796,0.00009783579,0.0041187285],"genre_scores_gemma":[0.0304598,0.006449405,0.0010673514,0.81957555,0.12400999,0.00007157127,0.00009887437,0.00006264432,0.01820493],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993563,0.00013883687,0.00008364869,0.00010119755,0.00021011739,0.000109891655],"domain_scores_gemma":[0.9976031,0.0011601155,0.00019183215,0.000098957236,0.000562852,0.000383184],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010912851,0.0005399807,0.0006761621,0.000399496,0.0014960114,0.0014467377,0.001080605,0.016789535,0.003688245],"category_scores_gemma":[0.006080092,0.00035459653,0.00060609536,0.00025047627,0.001267961,0.00131981,0.00048652894,0.011514346,0.003442297],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015162543,0.00009442484,0.0021821228,0.00006452578,0.000020737934,0.012863006,0.00009448501,0.00010026369,0.0010621783,0.0023954804,0.9557418,0.025229272],"study_design_scores_gemma":[0.0004365531,0.00027175178,0.0061206897,0.00027224777,0.00008845639,0.033267777,0.0006089532,0.0024793393,0.002590981,0.016746605,0.9370021,0.00011454317],"about_ca_topic_score_codex":0.0020931698,"about_ca_topic_score_gemma":0.0029528742,"teacher_disagreement_score":0.016789535,"about_ca_system_score_codex":0.001740697,"about_ca_system_score_gemma":0.0015023671,"threshold_uncertainty_score":0.012629688},"labels":[],"label_agreement":null},{"id":"W4306360085","doi":"10.1172/jci164219","title":"The curious case of tryptophan in pregnancy","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"University of Toronto; Heart and Stroke Foundation of Canada","keywords":"Preeclampsia; Pregnancy; Kynurenine; Medicine; Fetus; Kidney; Kynurenine pathway; Ischemia; Tryptophan; Physiology; Immunology; Endocrinology; Bioinformatics; Internal medicine; Biology; Genetics","score_opus":0.1089360297782825,"score_gpt":0.3951994232567567,"score_spread":0.28626339347847424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306360085","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031370418,0.02382217,0.00024034236,0.95468676,0.014000829,0.000016599019,0.000019729197,0.000033871616,0.0040425886],"genre_scores_gemma":[0.047750566,0.021657167,0.00063318084,0.8445915,0.08214059,0.000052267413,0.000017957469,0.000026248994,0.0031304439],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980363,0.0010013888,0.00020901239,0.0002566232,0.00031211617,0.00018460887],"domain_scores_gemma":[0.99567705,0.0031007405,0.00025840278,0.00020037906,0.00025200009,0.00051141076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018081521,0.0006946215,0.0010808747,0.00059008074,0.0025704694,0.0019461754,0.0012011736,0.019603606,0.001017029],"category_scores_gemma":[0.01532095,0.00046022012,0.00066400954,0.00045850538,0.0030457682,0.0031360772,0.0010862568,0.017794702,0.0007017275],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027377193,0.00010963683,0.0045411815,0.0004715257,0.000085433385,0.16375826,0.0017142228,0.00017099758,0.0010346243,0.024235012,0.75089103,0.05271428],"study_design_scores_gemma":[0.00019821104,0.00022950556,0.003951312,0.0014978135,0.00009523194,0.26147678,0.002391886,0.00070885906,0.0008271902,0.03293866,0.6955727,0.00011183693],"about_ca_topic_score_codex":0.0021028265,"about_ca_topic_score_gemma":0.0036261377,"teacher_disagreement_score":0.019603606,"about_ca_system_score_codex":0.0024044584,"about_ca_system_score_gemma":0.002014743,"threshold_uncertainty_score":0.017445624},"labels":[],"label_agreement":null},{"id":"W4307407906","doi":"10.1172/jci154684","title":"Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Saskatchewan","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Alabama Agricultural Experiment Station; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; McGill University","keywords":"Biology; Mitochondrion; Immunology; Immune system; Cell biology","score_opus":0.03587115929542393,"score_gpt":0.3032968487810136,"score_spread":0.26742568948558965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307407906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923225,0.0013516803,0.004355819,0.00021089886,0.00006595506,0.000054772714,0.00030869048,0.00014976606,0.0011799902],"genre_scores_gemma":[0.9972349,0.00048599645,0.0009869474,0.000039908355,0.000009644752,0.000040988532,0.00020931452,0.000012223345,0.0009801433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977165,0.000050622,0.00003085844,0.000047847156,0.00004467789,0.000054275413],"domain_scores_gemma":[0.9998149,0.000015171811,0.00006236569,0.000028521225,0.000016607733,0.000062497216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024486257,0.00035948603,0.00035962928,0.00039757052,0.00019958655,0.00033460604,0.00023775517,0.00040397688,0.001322945],"category_scores_gemma":[0.00017459277,0.00012703771,0.00030383136,0.00020738105,0.0004463213,0.00024693957,0.00027667047,0.0007947054,0.00024350714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042323724,0.00009501262,0.00034577202,0.00004837129,0.000013254986,0.00022990457,0.00003085438,0.00007124116,0.99744225,0.00020112714,0.000102961574,0.0009962224],"study_design_scores_gemma":[0.000079377845,0.0015313459,0.0051838863,0.000026100057,0.00004979291,0.0011833037,0.00012252941,0.00179341,0.9866947,0.0003101311,0.0030166025,0.000008875661],"about_ca_topic_score_codex":0.00034535196,"about_ca_topic_score_gemma":0.0006331194,"teacher_disagreement_score":0.001322945,"about_ca_system_score_codex":0.00032033157,"about_ca_system_score_gemma":0.00015853868,"threshold_uncertainty_score":0.0044257045},"labels":[],"label_agreement":null},{"id":"W4307717490","doi":"10.1172/jci163670","title":"Epigenetics in glaucoma: a link between DNA methylation and neurodegeneration","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Eye Institute; School of Medicine, Stanford University; National Institutes of Health; Children's Health Research Institute; U.S. Department of Veterans Affairs; American Glaucoma Society; Research to Prevent Blindness","keywords":"Optic nerve; Epigenetics; Neurodegeneration; Haploinsufficiency; Biology; Glaucoma; Normal tension glaucoma; Retinal degeneration; Genetics; DNA methylation; Protein arginine methyltransferase 5; Methyltransferase; Histone; Cell biology; Neuroscience; Methylation; Medicine; Gene; Pathology; Open angle glaucoma; Phenotype; Gene expression","score_opus":0.07509897116984104,"score_gpt":0.3561838916366371,"score_spread":0.28108492046679606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307717490","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016316505,0.016901374,0.00081269693,0.93475986,0.021232469,0.000037781174,0.000056512392,0.000110219145,0.009772665],"genre_scores_gemma":[0.18780984,0.024067754,0.0014196942,0.49439433,0.27741885,0.000065339314,0.00005215916,0.00004611796,0.014725931],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996152,0.00013904777,0.000049268205,0.000045233817,0.0000995095,0.000051724255],"domain_scores_gemma":[0.9989028,0.00058510614,0.0001457356,0.0000666861,0.00015301578,0.00014659145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069021154,0.00048834865,0.0005796647,0.00050739804,0.0012874508,0.00083615206,0.00045786359,0.010076855,0.002538125],"category_scores_gemma":[0.0030738115,0.000258127,0.00037328393,0.00038286048,0.0016110099,0.0011727633,0.00045619954,0.0061930665,0.0014244607],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008219794,0.0003105654,0.0140595455,0.0005176685,0.00009870458,0.14033128,0.0011378957,0.00035596007,0.014108006,0.015797019,0.7156922,0.09676907],"study_design_scores_gemma":[0.00077068695,0.0008815256,0.020275226,0.00073654857,0.00016470661,0.23603836,0.0011375122,0.002830073,0.005614267,0.041618507,0.68980026,0.00013240948],"about_ca_topic_score_codex":0.0008127255,"about_ca_topic_score_gemma":0.0013803691,"teacher_disagreement_score":0.010076855,"about_ca_system_score_codex":0.0011089097,"about_ca_system_score_gemma":0.0005731322,"threshold_uncertainty_score":0.00849086},"labels":[],"label_agreement":null},{"id":"W4308054132","doi":"10.1172/jci153943","title":"SCF-SKP2 E3 ubiquitin ligase links mTORC1/ER stress/ISR with YAP activation in murine renal cystogenesis","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; Kidney Foundation of Canada","keywords":"mTORC1; SKP2; Tauroursodeoxycholic acid; Biology; Cell biology; Ubiquitin ligase; Kinase; PI3K/AKT/mTOR pathway; Ribosomal protein s6; Unfolded protein response; Cancer research; Chemistry; Signal transduction; Ubiquitin; Biochemistry; P70-S6 Kinase 1; Endoplasmic reticulum","score_opus":0.031850899587604044,"score_gpt":0.3188883993612825,"score_spread":0.28703749977367843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308054132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950647,0.0009440738,0.0020728207,0.00014937672,0.000032024498,0.000030215575,0.0005978614,0.00011206049,0.0009969788],"genre_scores_gemma":[0.99577314,0.0005117067,0.0009803532,0.000039844646,0.000006801278,0.000045182896,0.00047103353,0.000018815033,0.0021531314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998229,0.000030320389,0.000023801833,0.000036206067,0.00004010766,0.00004658822],"domain_scores_gemma":[0.99986637,0.0000067286496,0.00005039447,0.000014913903,0.000010174474,0.000051444065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019816453,0.00039458257,0.00025062318,0.00042472893,0.00020804946,0.00027779886,0.00026597353,0.00032148804,0.0011674433],"category_scores_gemma":[0.00008851267,0.0003073572,0.0003806823,0.00018811123,0.00034220307,0.00020718656,0.0002684616,0.00056816067,0.00042708922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035370304,0.00004696684,0.00032402083,0.00003559252,0.000008303709,0.00009329238,0.000012054666,0.0001283382,0.99811894,0.00014324114,0.00006824023,0.00066723407],"study_design_scores_gemma":[0.000047566657,0.00033580035,0.004867092,0.0000073855117,0.000023147362,0.00034201203,0.000025808324,0.0014408558,0.99108326,0.000078100085,0.0017442515,0.000004717729],"about_ca_topic_score_codex":0.00078233355,"about_ca_topic_score_gemma":0.0011139043,"teacher_disagreement_score":0.0011674433,"about_ca_system_score_codex":0.00048308843,"about_ca_system_score_gemma":0.00027589736,"threshold_uncertainty_score":0.0039054751},"labels":[],"label_agreement":null},{"id":"W4308992051","doi":"10.1172/jci159348","title":"Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; McGill University Health Centre","funders":"Medical Research Council; NIH Clinical Center; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; Hackensack Meridian Health; NHLBI Division of Intramural Research; National Institute on Deafness and Other Communication Disorders; Wellcome Trust; National Institute of Allergy and Infectious Diseases; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Phaeohyphomycosis; Immunology; Macrophage; Biology; Immunologic Deficiency Syndromes; Medicine; Immune system; Microbiology; Genetics","score_opus":0.07757930275382934,"score_gpt":0.3798325641240747,"score_spread":0.30225326137024533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308992051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9994307,0.00017374298,0.00013721413,0.000013310663,0.000003449941,0.000007082331,0.000051592346,0.0000067260517,0.00017614712],"genre_scores_gemma":[0.99933016,0.00010934027,0.00016185634,0.00001869459,0.000002269534,0.0000066581374,0.00010623983,0.0000022603062,0.00026254443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988174,0.000024253759,0.00001823283,0.00002707269,0.000018136248,0.000030565938],"domain_scores_gemma":[0.99990296,0.000026730715,0.000016449072,0.000010106541,0.000007873152,0.000035885514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001266358,0.00038948987,0.0003033992,0.00016311812,0.00015871489,0.00022102176,0.00010693028,0.00024647455,0.0014341815],"category_scores_gemma":[0.00021754568,0.000098436656,0.0001550304,0.00009143879,0.00018277483,0.00009324804,0.00016034495,0.00032520416,0.00023477469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00097472034,0.00028887816,0.01047027,0.00006508911,0.000032995027,0.002835627,0.00009289788,0.00018611754,0.9796228,0.00012767296,0.00013344853,0.0051694163],"study_design_scores_gemma":[0.0004955957,0.0076020076,0.18166329,0.000056672936,0.00020981499,0.04584346,0.00032370276,0.003694396,0.75447524,0.0002037759,0.0054033617,0.000028742723],"about_ca_topic_score_codex":0.00040665743,"about_ca_topic_score_gemma":0.00037787828,"teacher_disagreement_score":0.0014341815,"about_ca_system_score_codex":0.00016655492,"about_ca_system_score_gemma":0.00012095951,"threshold_uncertainty_score":0.0047978163},"labels":[],"label_agreement":null},{"id":"W4308992074","doi":"10.1172/jci164747","title":"Does treating with anti–PD-1 to improve glomerular health come without a cost?","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Medicine; Urology; Chemistry; Intensive care medicine","score_opus":0.05180032849622195,"score_gpt":0.3846905068450426,"score_spread":0.3328901783488206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308992074","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00059064716,0.003936125,0.0002279268,0.9767289,0.017441405,0.000009572138,0.000022872277,0.00003587781,0.0010066289],"genre_scores_gemma":[0.005888937,0.0058954074,0.0006982942,0.89571965,0.089117765,0.000026414491,0.000026724301,0.000024443907,0.0026023604],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983467,0.00051266793,0.00026072562,0.00018803842,0.0005053305,0.00018652367],"domain_scores_gemma":[0.99261355,0.0035056712,0.00052221667,0.00025699308,0.0018746341,0.0012269635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0033279858,0.00083713426,0.0014280233,0.00073152356,0.0019912755,0.0020740437,0.0015200487,0.023902453,0.005526054],"category_scores_gemma":[0.019092564,0.00042407957,0.0012617242,0.0005684063,0.0021239412,0.0052457643,0.00091404485,0.025398567,0.005390396],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014250797,0.00016232094,0.0020989967,0.00021238142,0.00006514206,0.010492087,0.00016600284,0.0001588491,0.0004879653,0.003528765,0.93884426,0.043640777],"study_design_scores_gemma":[0.0002556816,0.00033925622,0.0024033743,0.00084156595,0.00010086923,0.0352724,0.0005916141,0.001022085,0.0005714669,0.018058058,0.9403967,0.00014696331],"about_ca_topic_score_codex":0.0012905151,"about_ca_topic_score_gemma":0.0025690822,"teacher_disagreement_score":0.023902453,"about_ca_system_score_codex":0.0022832768,"about_ca_system_score_gemma":0.0015080407,"threshold_uncertainty_score":0.01848656},"labels":[],"label_agreement":null},{"id":"W4309202711","doi":"10.1172/jci159344","title":"Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Anesthesia and Neurotoxicity Research","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; Université de Montréal; Montreal Neurological Institute and Hospital; Canadian Sleep & Circadian Network; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Parvalbumin; Interneuron; Neuroscience; Hippocampus; Memory consolidation; Excitatory postsynaptic potential; Inhibitory postsynaptic potential; Biology","score_opus":0.16125083708484184,"score_gpt":0.39029504350244354,"score_spread":0.2290442064176017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309202711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949903,0.0010051426,0.0024796072,0.00014899069,0.000033132714,0.000054280696,0.00042857276,0.00020227765,0.00065778976],"genre_scores_gemma":[0.9922694,0.0011126611,0.0023499727,0.00014727745,0.00002227288,0.00018408119,0.00057211804,0.00007132271,0.003270854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99968207,0.000029450888,0.000036643905,0.00009784194,0.00005760268,0.00009652366],"domain_scores_gemma":[0.99960333,0.000025629075,0.00020306959,0.000034303273,0.000025065838,0.00010870589],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002723163,0.00074789574,0.00044208614,0.0007983598,0.00026416732,0.00040473125,0.0006480937,0.00077634957,0.0014077552],"category_scores_gemma":[0.00020956076,0.00038660114,0.00040792802,0.00022236166,0.0006270374,0.0005433526,0.00038004192,0.001723558,0.0004370129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037263084,0.00021064357,0.0007329731,0.000043849817,0.000017159982,0.00020518282,0.0000543727,0.000088894034,0.99546176,0.00013207897,0.000074453455,0.002606011],"study_design_scores_gemma":[0.00014216437,0.002477279,0.02138759,0.000048336988,0.00009598264,0.0013158348,0.00012623673,0.0017330121,0.97039276,0.00023898957,0.0020231286,0.000018698305],"about_ca_topic_score_codex":0.00089152897,"about_ca_topic_score_gemma":0.00189453,"teacher_disagreement_score":0.0014077552,"about_ca_system_score_codex":0.00050449336,"about_ca_system_score_gemma":0.00035854225,"threshold_uncertainty_score":0.004709363},"labels":[],"label_agreement":null},{"id":"W4312001791","doi":"10.1172/jci164915","title":"Loss of LGR4/GPR48 causes severe neonatal salt wasting due to disrupted WNT signaling altering adrenal zonation","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Société Française d’Endocrinologie; Ligue Contre le Cancer; Recordati Rare Diseases; National Science Foundation","keywords":"Wnt signaling pathway; Endocrinology; Internal medicine; Aldosterone; Adrenal cortex; Biology; Signal transduction; Cell biology; Medicine","score_opus":0.09386215309204636,"score_gpt":0.3704240081121999,"score_spread":0.2765618550201535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312001791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99744403,0.00027563534,0.001134714,0.00007303311,0.000014308688,0.000014069184,0.0003801166,0.000100008605,0.0005640593],"genre_scores_gemma":[0.99725705,0.00034614245,0.00091869285,0.000048534006,0.0000061448786,0.000023869496,0.00036072588,0.00003390259,0.0010049008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979645,0.000035311587,0.000035032346,0.000043303586,0.00005332867,0.00003661344],"domain_scores_gemma":[0.9998549,0.000026781816,0.000054816945,0.000014662955,0.0000052799173,0.000043573407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119341224,0.0005281714,0.0002633357,0.0004566122,0.00012505768,0.00015262449,0.00030451486,0.00038596202,0.0017470231],"category_scores_gemma":[0.00022447223,0.00021362076,0.00036458866,0.00017931429,0.000375176,0.000105231906,0.00037544037,0.00045177052,0.00038260472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002878203,0.00003951519,0.0017555803,0.00004316672,0.000020240403,0.004970995,0.00004138752,0.00017308022,0.99034727,0.00012816179,0.000088077235,0.002104683],"study_design_scores_gemma":[0.00015263719,0.0010161194,0.08132065,0.000035753998,0.00017273624,0.04232824,0.00024373263,0.003276611,0.86650175,0.00024414907,0.004673617,0.000033934502],"about_ca_topic_score_codex":0.0011174664,"about_ca_topic_score_gemma":0.0011055098,"teacher_disagreement_score":0.0017470231,"about_ca_system_score_codex":0.00023898175,"about_ca_system_score_gemma":0.00020526236,"threshold_uncertainty_score":0.0058443546},"labels":[],"label_agreement":null},{"id":"W4313427324","doi":"10.1172/jci154754","title":"Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Natural Science Foundation of China","keywords":"Immunity; Endocytic cycle; Canagliflozin; Degradation (telecommunications); Chemistry; Immunology; Biology; Immune system; Endocytosis; Computer science; Biochemistry; Cell; Endocrinology","score_opus":0.05954777369941462,"score_gpt":0.3626706859830168,"score_spread":0.3031229122836022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313427324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857863,0.005839451,0.005369887,0.00035685668,0.00007775345,0.000056469926,0.00016578435,0.000178905,0.002168474],"genre_scores_gemma":[0.99650925,0.0009321732,0.0013995874,0.000106802305,0.000017682303,0.000022284117,0.000115125426,0.0000058031505,0.000891182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999039,0.000015863863,0.000006654182,0.000020649848,0.00002483487,0.000028043167],"domain_scores_gemma":[0.99995494,0.0000075329854,0.000016650565,0.000004771204,0.000006317769,0.0000097963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013887852,0.00022471657,0.0001852441,0.00020025542,0.00010200694,0.00035475785,0.00011759726,0.00023189306,0.00068825675],"category_scores_gemma":[0.00009992527,0.000074238036,0.00022165423,0.000094562114,0.00015956999,0.0001765905,0.00011568061,0.00041790656,0.00014454282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007680217,0.00015762291,0.0015075358,0.00016763661,0.000035157078,0.00009956808,0.000020251104,0.00045519279,0.9837563,0.00050039554,0.00036424297,0.012168028],"study_design_scores_gemma":[0.00015441977,0.000860159,0.006603435,0.000009937364,0.00005594842,0.00038973108,0.000019627723,0.0039550522,0.9798321,0.00021035646,0.0079010045,0.00000825658],"about_ca_topic_score_codex":0.00034804322,"about_ca_topic_score_gemma":0.0006236242,"teacher_disagreement_score":0.00068825675,"about_ca_system_score_codex":0.00049114286,"about_ca_system_score_gemma":0.00022828433,"threshold_uncertainty_score":0.0035635233},"labels":[],"label_agreement":null},{"id":"W4313427367","doi":"10.1172/jci158903","title":"Longitudinal liver sampling in patients with chronic hepatitis B starting antiviral therapy reveals hepatotoxic CD8+ T cells","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"Deutsche Forschungsgemeinschaft; Gilead Sciences","keywords":"CD8; Immunology; Immune system; Cytotoxic T cell; Pathogenesis; T cell; Population; Cirrhosis; Hepatocyte; Biology; Hepatitis; Medicine; Internal medicine; In vitro","score_opus":0.15512810928406745,"score_gpt":0.41680328430164176,"score_spread":0.2616751750175743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313427367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99953747,0.00011717747,0.00013980226,0.000011241074,0.0000011953076,0.000007842926,0.0000321705,0.0000050541144,0.00014809766],"genre_scores_gemma":[0.9995826,0.000037890586,0.0001469113,0.000026278598,0.0000038155304,0.000007617962,0.00009019182,0.0000010935329,0.00010356136],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998903,0.00003285166,0.000011631955,0.000030738556,0.000015539083,0.00001884579],"domain_scores_gemma":[0.9998233,0.000038803544,0.000047120775,0.000014948547,0.000016725588,0.000059228405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021969914,0.00014344153,0.00022371138,0.00022687153,0.00018559824,0.00020727646,0.000057952006,0.00018460283,0.0006316749],"category_scores_gemma":[0.00041305993,0.000111243935,0.00008771001,0.00013559783,0.00013562136,0.00014143792,0.00015624063,0.00021635006,0.0001342928],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027497264,0.00020214336,0.88987684,0.000035745783,0.000026670063,0.0010982754,0.00038628813,0.00010230722,0.09383674,0.000028837761,0.00014207434,0.011514417],"study_design_scores_gemma":[0.000051444025,0.0027514216,0.983832,0.000009269108,0.000037630256,0.0032003764,0.00029328966,0.00064318074,0.008522768,0.000036786816,0.0006158453,0.000005927253],"about_ca_topic_score_codex":0.00044479466,"about_ca_topic_score_gemma":0.0006494552,"teacher_disagreement_score":0.0006316749,"about_ca_system_score_codex":0.00011554787,"about_ca_system_score_gemma":0.000092719856,"threshold_uncertainty_score":0.0021131039},"labels":[],"label_agreement":null},{"id":"W4313545883","doi":"10.1172/jci160036","title":"A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"National Heart, Lung, and Blood Institute; Korea National Institute of Health; Cleveland Clinic; National Center for Advancing Translational Sciences; Yale University","keywords":"Biology; Renin–angiotensin system; Neural crest; Enhancer; Cell biology; Kidney development; Gene expression; Gene; Endocrinology; Internal medicine; Molecular biology; Genetics; Blood pressure; Medicine; Embryonic stem cell","score_opus":0.2012056382384472,"score_gpt":0.385608956401252,"score_spread":0.18440331816280478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313545883","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3545595,0.010161255,0.6087159,0.0029092736,0.0005672348,0.0002438873,0.0058033625,0.004129877,0.012909737],"genre_scores_gemma":[0.85907674,0.0052793543,0.12877071,0.00040670155,0.00008085168,0.00024280189,0.0031585132,0.00014920378,0.0028352502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973637,0.000058717676,0.000012547173,0.00011133469,0.000052219006,0.000028840603],"domain_scores_gemma":[0.99981207,0.00008882272,0.000031124804,0.00003047149,0.000016563967,0.000021009666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006748797,0.00065915176,0.0007414254,0.00061651017,0.0004731042,0.0013203255,0.0007439332,0.0006771161,0.0025164902],"category_scores_gemma":[0.0004743695,0.00045781076,0.0011958168,0.00047551858,0.00057897845,0.0005262686,0.0008746752,0.0013957263,0.00044830146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035121376,0.00014491036,0.0075454903,0.001068034,0.0004272932,0.0005519909,0.00017332587,0.035295527,0.8809299,0.038529307,0.001649015,0.033334028],"study_design_scores_gemma":[0.00017424724,0.0011089182,0.0260348,0.00017282827,0.0007840513,0.0012675815,0.00026060204,0.5055265,0.36282626,0.048259985,0.05343344,0.00015076362],"about_ca_topic_score_codex":0.001792881,"about_ca_topic_score_gemma":0.002506393,"teacher_disagreement_score":0.0025164902,"about_ca_system_score_codex":0.001022173,"about_ca_system_score_gemma":0.00080959656,"threshold_uncertainty_score":0.008418441},"labels":[],"label_agreement":null},{"id":"W4313545983","doi":"10.1172/jci165245","title":"Clonally expanded HIV-1 proviruses with 5′-leader defects can give rise to nonsuppressible residual viremia","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal; Clinique Paro Excellence","funders":"National Institute of General Medical Sciences; NIH Office of the Director; National Heart, Lung, and Blood Institute; Center for AIDS Research, University of Washington; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Johns Hopkins University; Howard Hughes Medical Institute","keywords":"Viremia; Virology; Biology; Viral load; Antiretroviral therapy; Viral replication; Human immunodeficiency virus (HIV); Virus","score_opus":0.0885554254870092,"score_gpt":0.3778661466894443,"score_spread":0.28931072120243506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313545983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983045,0.00020142872,0.001008986,0.000014278632,0.0000043384753,0.000022979155,0.000099975434,0.000021899654,0.00032163117],"genre_scores_gemma":[0.9982527,0.000077480996,0.0010223202,0.0000410971,0.000004811081,0.000020310728,0.00030643892,0.000013387599,0.0002613872],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997435,0.00003901216,0.00002340936,0.000059784343,0.0000844965,0.000049771465],"domain_scores_gemma":[0.9995771,0.00015548969,0.00012560349,0.000054366064,0.000047244415,0.000040277322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033677506,0.00027846365,0.0002219596,0.00019883152,0.00016149975,0.0003102509,0.00023714299,0.00027991674,0.0010768545],"category_scores_gemma":[0.0006019311,0.00010447611,0.00017871977,0.00014856653,0.00021322437,0.00013909003,0.00023264003,0.00040044883,0.00021771374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020744812,0.000110504654,0.057600543,0.00005864187,0.000029268564,0.0007823473,0.00018307425,0.00033464885,0.9284463,0.00021771478,0.00012547699,0.011904119],"study_design_scores_gemma":[0.00006026922,0.0027446381,0.25396323,0.000031500986,0.00021457022,0.012551665,0.0003796238,0.0050442857,0.71947193,0.00067689555,0.00483686,0.000024497991],"about_ca_topic_score_codex":0.000504174,"about_ca_topic_score_gemma":0.0007337714,"teacher_disagreement_score":0.0010768545,"about_ca_system_score_codex":0.00021492073,"about_ca_system_score_gemma":0.00015596971,"threshold_uncertainty_score":0.0036023855},"labels":[],"label_agreement":null},{"id":"W4316661361","doi":"10.1172/jci167444","title":"Lessons learned: from mentored to mentor","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Astellas Pharma; Canadian Institute for Advanced Research","keywords":"Excellence; Medical education; Engineering ethics; Medical school; Medicine; Political science; Engineering","score_opus":0.3014432722189833,"score_gpt":0.46270229151794223,"score_spread":0.16125901929895892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316661361","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002879305,0.012862204,0.004447947,0.92248994,0.039769683,0.00006994719,0.00009753028,0.0005888372,0.016794534],"genre_scores_gemma":[0.13722529,0.025888074,0.012656736,0.72123003,0.026739033,0.00043091233,0.00038431177,0.0013019774,0.07414374],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9457056,0.0351092,0.0015073358,0.0031903547,0.009197058,0.0052905483],"domain_scores_gemma":[0.87165827,0.020122083,0.0039924756,0.0066356407,0.023832206,0.073759235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.043770544,0.0015378285,0.0012429866,0.0014924848,0.010822042,0.027622055,0.006484339,0.008819188,0.02727506],"category_scores_gemma":[0.11414538,0.00060880487,0.0013340216,0.0013563146,0.013927215,0.026456391,0.021771217,0.028578809,0.013178832],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008309882,0.0001753768,0.0014213991,0.0005372224,0.00006296368,0.0007865369,0.01640944,0.00013618817,0.00022424529,0.025728773,0.81946063,0.13497417],"study_design_scores_gemma":[0.00007619356,0.00030512965,0.00065197574,0.0017336283,0.000031177526,0.0012806492,0.033803016,0.0001841418,0.0002206162,0.04147062,0.92014784,0.000094954914],"about_ca_topic_score_codex":0.002634702,"about_ca_topic_score_gemma":0.0063234516,"teacher_disagreement_score":0.043770544,"about_ca_system_score_codex":0.006927912,"about_ca_system_score_gemma":0.024785507,"threshold_uncertainty_score":0.23148352},"labels":[],"label_agreement":null},{"id":"W4316661384","doi":"10.1172/jci163498","title":"BMX controls 3βHSD1 and sex steroid biosynthesis in cancer","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"U.S. Army Medical Research and Development Command; Astellas Pharma; National Cancer Institute; National Institutes of Health; Case Western Reserve University; Prostate Cancer Foundation; U.S. Department of Defense","keywords":"Aromatase; Androgen; Endocrinology; Prostate cancer; Androgen receptor; Internal medicine; Testosterone (patch); Intracrine; Cancer research; Biology; Cancer; Medicine; Hormone; Receptor; Breast cancer; Paracrine signalling","score_opus":0.19641566806755484,"score_gpt":0.47652843413848117,"score_spread":0.28011276607092633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316661384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98451763,0.007471006,0.0024158768,0.0003878567,0.000128121,0.000044960892,0.00070221897,0.0002494798,0.004082819],"genre_scores_gemma":[0.9891695,0.0020688944,0.0010529406,0.00011709364,0.000020045889,0.00004024695,0.00053452444,0.00003377736,0.0069631143],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99985147,0.000026229802,0.0000081691405,0.00004221183,0.000037016307,0.000034795263],"domain_scores_gemma":[0.99990606,0.000008577328,0.000035849913,0.0000085011525,0.000006749445,0.000034150304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010617383,0.00023468921,0.00018291779,0.00021271549,0.00021711072,0.00038998623,0.00023793434,0.0002164683,0.00344039],"category_scores_gemma":[0.000120852754,0.0001588663,0.00016534253,0.0001388813,0.000238491,0.00013600326,0.00023819695,0.00036416072,0.00049677055],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006091572,0.00007608357,0.0013062287,0.000041691186,0.000009633307,0.000072781135,0.000024788527,0.00008351491,0.989632,0.00046358368,0.00033069088,0.007349811],"study_design_scores_gemma":[0.00012913522,0.0009769532,0.07961154,0.000019018149,0.00004543295,0.00075187004,0.00012906342,0.0014781131,0.8927568,0.00042166034,0.023663549,0.000016877948],"about_ca_topic_score_codex":0.00083037536,"about_ca_topic_score_gemma":0.0012575268,"teacher_disagreement_score":0.00344039,"about_ca_system_score_codex":0.00039884014,"about_ca_system_score_gemma":0.00027682722,"threshold_uncertainty_score":0.01150924},"labels":[],"label_agreement":null},{"id":"W4316928297","doi":"10.1172/jci166710","title":"BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Steven and Alexandra Cohen Foundation; Connecticut Children's Medical Center; Global Lyme Alliance; East Carolina University","keywords":"rpoS; Biology; Borrelia burgdorferi; Regulon; Sigma factor; rpoN; Psychological repression; Transcription (linguistics); RNA polymerase; Microbiology; Cell biology; Genetics; Regulation of gene expression; Gene; Gene expression; RNA; Promoter","score_opus":0.03920791187023144,"score_gpt":0.3353410682005961,"score_spread":0.2961331563303647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316928297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99422646,0.0020557758,0.0021942146,0.00007699699,0.000019438241,0.000010884613,0.00037237967,0.00012714844,0.0009166529],"genre_scores_gemma":[0.99602354,0.0003970692,0.0012305658,0.00009051114,0.000011140255,0.00002155679,0.0006847145,0.00004263261,0.0014981856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999782,0.000027655016,0.000014579454,0.00007452172,0.000055449967,0.00004579692],"domain_scores_gemma":[0.99989057,0.000010665018,0.00004549268,0.000012780337,0.000013112855,0.00002738323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014150712,0.00030673455,0.00022135202,0.00016473839,0.00011513224,0.0003540294,0.00014393876,0.0001944939,0.0005926927],"category_scores_gemma":[0.000111582944,0.00019901132,0.00022313259,0.000076871824,0.00029419884,0.00017238276,0.00032963254,0.00036912764,0.00041024073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034107983,0.0000030627004,0.00027061615,0.0000122122265,0.0000014951955,0.000014617487,0.000007165408,0.000014141769,0.9992157,0.000032735108,0.000014067799,0.00037998604],"study_design_scores_gemma":[0.000020820815,0.00028668033,0.066729896,0.000014531459,0.000026380134,0.000409761,0.000103064755,0.0014774086,0.9273031,0.00013333984,0.0034823872,0.000012614018],"about_ca_topic_score_codex":0.00022277333,"about_ca_topic_score_gemma":0.00039861928,"teacher_disagreement_score":0.0005926927,"about_ca_system_score_codex":0.00017159886,"about_ca_system_score_gemma":0.0001283284,"threshold_uncertainty_score":0.001982689},"labels":[],"label_agreement":null},{"id":"W4319656188","doi":"10.1172/jci161944","title":"A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; Université de Lausanne; Wellcome Trust; Francis Crick Institute; Cancer Research UK","keywords":"Tuberculosis; Chemistry; Terpene; Nucleoside; Biochemistry; Pathology; Medicine","score_opus":0.04568441172932159,"score_gpt":0.3413257984592113,"score_spread":0.2956413867298897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319656188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99676275,0.0017816931,0.0005530118,0.00008547026,0.000020816427,0.000019864197,0.00012857014,0.000027657354,0.0006201603],"genre_scores_gemma":[0.997056,0.0010522534,0.00075823435,0.000047162484,0.00001182207,0.000022630316,0.00020726337,0.00000701951,0.00083769485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994063,0.000014060831,0.000005630485,0.00001201586,0.000012558526,0.000015119117],"domain_scores_gemma":[0.999949,0.000014253883,0.000012041036,0.0000073112583,0.000004939643,0.000012581959],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000955054,0.00019734171,0.00016167585,0.0001411652,0.00010358006,0.00014929517,0.00008627048,0.00024092916,0.0007663022],"category_scores_gemma":[0.00015477768,0.00007658654,0.00009378908,0.0001222205,0.00015910325,0.000106849344,0.00014370753,0.00032585245,0.0001611163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019357855,0.000019513449,0.00010758949,0.000018582574,0.0000017733129,0.00006694485,0.0000074515788,0.00001171596,0.99853766,0.000014223046,0.000013649501,0.0010073427],"study_design_scores_gemma":[0.000049530914,0.00066278776,0.0033392916,0.0000066768093,0.0000089029845,0.00038869178,0.000017408258,0.00021469132,0.99425054,0.000034148066,0.001025507,0.0000018462189],"about_ca_topic_score_codex":0.00023084895,"about_ca_topic_score_gemma":0.0004515529,"teacher_disagreement_score":0.0007663022,"about_ca_system_score_codex":0.00013210268,"about_ca_system_score_gemma":0.00014061213,"threshold_uncertainty_score":0.0025635362},"labels":[],"label_agreement":null},{"id":"W4320709587","doi":"10.1172/jci159757","title":"Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Montreal Clinical Research Institute; Hôpital Maisonneuve-Rosemont","funders":"Alcon Research Institute; Japan Society for the Promotion of Science; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Diabetes Canada; Natural Sciences and Engineering Research Council of Canada; Foundation Fighting Blindness; BrightFocus Foundation; Université de Montréal","keywords":"Macular degeneration; Microglia; Retinal degeneration; Medicine; Retinal; Peripheral; Biology; Immunology; Ophthalmology; Internal medicine; Inflammation","score_opus":0.087388646728236,"score_gpt":0.34476825249636417,"score_spread":0.2573796057681282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320709587","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921158,0.0040289946,0.0014371866,0.00015432495,0.000053592943,0.000032090404,0.0003860702,0.00007100318,0.0017209806],"genre_scores_gemma":[0.99360895,0.002031621,0.0010233935,0.0001443901,0.000022117782,0.00006304905,0.00026759313,0.000011252208,0.0028276413],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987805,0.000022164892,0.0000132126,0.00003217029,0.000022782584,0.000031564465],"domain_scores_gemma":[0.99993396,0.0000038379367,0.00002426243,0.000008155211,0.000011509709,0.000018149256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018011249,0.00030320138,0.00024337415,0.0002770852,0.00017019243,0.00023494556,0.0001018085,0.00026112283,0.0012890815],"category_scores_gemma":[0.0001313275,0.00009743765,0.00021560153,0.00009058342,0.00021669484,0.00018971434,0.00027387857,0.0005040089,0.00024126064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093103194,0.00019721368,0.007022197,0.0002132071,0.000032477088,0.00071451167,0.0001565642,0.00010709629,0.9741805,0.00037671856,0.00043197526,0.015636442],"study_design_scores_gemma":[0.000109497996,0.0027486335,0.46031776,0.00018249363,0.00015687378,0.0049857763,0.00062449876,0.0020074185,0.5116768,0.0015939594,0.015561574,0.000034701574],"about_ca_topic_score_codex":0.00042079622,"about_ca_topic_score_gemma":0.0009264881,"teacher_disagreement_score":0.0012890815,"about_ca_system_score_codex":0.00022714729,"about_ca_system_score_gemma":0.00018223884,"threshold_uncertainty_score":0.004312396},"labels":[],"label_agreement":null},{"id":"W4320709875","doi":"10.1172/jci165654","title":"Molecular pathways that drive diabetic kidney disease","year":2023,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":315,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Kidney; Albuminuria; Kidney disease; Endocrinology; Diabetes mellitus; Podocyte; Internal medicine; Oxidative stress; Renal function; Diabetic nephropathy; Fibrosis; Medicine; Biology; Actin cytoskeleton; Proteinuria; Cell; Cytoskeleton; Biochemistry","score_opus":0.19213020124247868,"score_gpt":0.4263697159941644,"score_spread":0.23423951475168572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320709875","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016377954,0.9977302,0.00013625562,0.0005518287,0.00029620997,0.000006166291,0.000026253474,0.0000131855995,0.0010761918],"genre_scores_gemma":[0.00073313084,0.9982664,0.00012444446,0.00024706853,0.00013640322,0.00000694508,0.00003448419,0.0000010387108,0.0004501281],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998497,0.000025350893,0.000020618309,0.000024877163,0.000055821532,0.000023651206],"domain_scores_gemma":[0.99983585,0.000046745838,0.000026381518,0.000006060837,0.000060205723,0.000024763864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045755706,0.0008211644,0.001061576,0.0015382804,0.0002932649,0.0010406639,0.000840643,0.0009156334,0.003446022],"category_scores_gemma":[0.00049947173,0.00020692559,0.0005069666,0.00128235,0.00041453933,0.0010455557,0.00071377086,0.0021064428,0.001982783],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013277483,0.000113627466,0.00039870397,0.01518971,0.0001629039,0.00028997395,0.00005937723,0.0004243465,0.0026138232,0.007954574,0.05182349,0.9208366],"study_design_scores_gemma":[0.000031397132,0.00010631344,0.0013384215,0.004300462,0.0001306972,0.0014206212,0.000055725428,0.00013417608,0.00074796245,0.005012805,0.9867012,0.000020156062],"about_ca_topic_score_codex":0.0007306423,"about_ca_topic_score_gemma":0.0014783442,"teacher_disagreement_score":0.003446022,"about_ca_system_score_codex":0.0006612829,"about_ca_system_score_gemma":0.0010371978,"threshold_uncertainty_score":0.011528075},"labels":[],"label_agreement":null},{"id":"W4321004502","doi":"10.1172/jci162324","title":"Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill Genome Centre; McGill University","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Fondation du cancer du sein du Québec; Fonds de Recherche du Québec - Santé; Stand Up To Cancer Canada; Stand Up To Cancer; U.S. Department of Defense; McGill University; Congressionally Directed Medical Research Programs; Breast Cancer Research Foundation","keywords":"FOXM1; Proto-oncogene tyrosine-protein kinase Src; Cancer research; Breast cancer; Biology; Cell cycle; Metastasis; Cancer; Cell growth; Tumor progression; Cell biology; Signal transduction; Genetics","score_opus":0.03762494615914933,"score_gpt":0.35626242710783873,"score_spread":0.3186374809486894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321004502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99716103,0.0006419048,0.0011475434,0.000073018295,0.000008225698,0.000011687719,0.00008250372,0.00003601046,0.00083807437],"genre_scores_gemma":[0.9981754,0.0002555033,0.0007095762,0.000018661114,0.0000031087889,0.000010942519,0.00008133997,0.000004666818,0.00074086885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999882,0.000015201505,0.0000050568688,0.000030850573,0.000032498887,0.000034412333],"domain_scores_gemma":[0.9999509,0.0000060877433,0.000017453833,0.0000050969884,0.0000042705,0.000016203665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015101112,0.00016011439,0.00017211669,0.00016761167,0.00015437603,0.00020826778,0.00012117655,0.00016161591,0.0005792911],"category_scores_gemma":[0.000083314146,0.00011491847,0.00010804998,0.000119412594,0.00023475231,0.00007918115,0.0002244093,0.0003288723,0.00012557425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006653881,0.00002088876,0.00046183122,0.000012144318,0.0000019816584,0.000023592811,0.000008639892,0.00007027616,0.99812514,0.00018076827,0.000030090572,0.0009980255],"study_design_scores_gemma":[0.000030450356,0.0003071051,0.011058436,0.00000450632,0.0000103561515,0.00025840875,0.000032315926,0.0029710403,0.98231345,0.00015452511,0.0028553514,0.000004120709],"about_ca_topic_score_codex":0.0007884214,"about_ca_topic_score_gemma":0.0015475603,"teacher_disagreement_score":0.0007884214,"about_ca_system_score_codex":0.000474351,"about_ca_system_score_gemma":0.0002979235,"threshold_uncertainty_score":0.0034416318},"labels":[],"label_agreement":null},{"id":"W4321445548","doi":"10.1172/jci162685","title":"Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Wellcome Trust; National Human Genome Research Institute; Leukemia and Lymphoma Society","keywords":"GATA2; Haematopoiesis; Gene; Biology; Zinc finger; Signal transduction; Gene expression; Genetics; Regulation of gene expression; Cancer research; Cell biology; Transcription factor; Stem cell","score_opus":0.06980995491278112,"score_gpt":0.35300984374592376,"score_spread":0.2831998888331426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321445548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932453,0.00047115472,0.0042248843,0.00014059435,0.000031487107,0.00002138877,0.00055445277,0.00014209936,0.0011686261],"genre_scores_gemma":[0.9971252,0.00015338474,0.0016420743,0.000071243914,0.0000075762377,0.0000073918823,0.00025862566,0.000020297117,0.0007142076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998896,0.000016223408,0.000010124232,0.000035619665,0.000031582986,0.000016761716],"domain_scores_gemma":[0.9999399,0.000014580268,0.000016374677,0.0000064204196,0.0000031781776,0.00001950994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000936177,0.00044644618,0.00018192148,0.00019821367,0.00015222683,0.00014866302,0.0001345167,0.00039488173,0.0014588104],"category_scores_gemma":[0.000115241746,0.00009868873,0.00018947426,0.00014789459,0.00027559424,0.00007583812,0.00017184201,0.00033836532,0.00026437014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014161615,0.000019806865,0.0022486034,0.000017757891,0.000014332775,0.0026914547,0.000014556694,0.00014909764,0.9921727,0.00026706725,0.0000988904,0.0021640672],"study_design_scores_gemma":[0.00006990658,0.00052453193,0.06134189,0.000021025764,0.00008549269,0.041269746,0.000090697526,0.0031751562,0.88452345,0.0008367501,0.008042394,0.000018951967],"about_ca_topic_score_codex":0.00048432758,"about_ca_topic_score_gemma":0.00092018826,"teacher_disagreement_score":0.0014588104,"about_ca_system_score_codex":0.00016163486,"about_ca_system_score_gemma":0.00015808869,"threshold_uncertainty_score":0.0048802495},"labels":[],"label_agreement":null},{"id":"W4322616560","doi":"10.1172/jci163239","title":"Epsilon toxin–producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hatch (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; National Institutes of Health; York University; Multiple Sclerosis Society; Weill Cornell Medical College; National Multiple Sclerosis Society","keywords":"Clostridium perfringens; Microbiology; Immune system; Microbiome; Biology; Multiple sclerosis; Gut microbiome; Toxin; Microbial toxins; Immunology; Bacteria; Bioinformatics; Genetics","score_opus":0.1651832658942822,"score_gpt":0.3751648304845719,"score_spread":0.2099815645902897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322616560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976841,0.0008149427,0.00055050745,0.00009978942,0.000008616988,0.000008732793,0.000055311826,0.000013538028,0.0007644702],"genre_scores_gemma":[0.99732435,0.0007488386,0.00091104576,0.0001317387,0.000013886748,0.00000913551,0.00011921208,0.000004951123,0.0007367783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982303,0.0000335077,0.000010113957,0.000037811464,0.00003732087,0.00005824161],"domain_scores_gemma":[0.99986863,0.000017971655,0.0000481696,0.00000942469,0.000024903578,0.000030860076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014811559,0.00023472814,0.00019464325,0.0002997049,0.00021643795,0.0004262241,0.00009271551,0.00029497934,0.00095364853],"category_scores_gemma":[0.00029859802,0.00007898718,0.00012467346,0.0002145526,0.00018051773,0.00020460736,0.00032329158,0.0002869903,0.00015852597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040710357,0.000066611414,0.024829643,0.000117117255,0.000019725801,0.00050928874,0.00020465993,0.000088951565,0.95823085,0.00015285754,0.00018394932,0.01518925],"study_design_scores_gemma":[0.00006244734,0.0020362372,0.6408794,0.00019177438,0.00011578205,0.007059771,0.001614539,0.0017119924,0.33235988,0.0008054093,0.013131261,0.000031505842],"about_ca_topic_score_codex":0.0010270062,"about_ca_topic_score_gemma":0.0012058079,"teacher_disagreement_score":0.0010270062,"about_ca_system_score_codex":0.00020031979,"about_ca_system_score_gemma":0.00018951365,"threshold_uncertainty_score":0.003190279},"labels":[],"label_agreement":null},{"id":"W4322624753","doi":"10.1172/jci159940","title":"CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Congressionally Directed Medical Research Programs; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; U.S. Department of Defense; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Cancer Prevention and Research Institute of Texas; Bristol-Myers Squibb","keywords":"Biology; GATA3; Ribosome profiling; Transcription factor; CRISPR; Computational biology; Genetics; Gene; Cancer research; Translation (biology); Messenger RNA","score_opus":0.1593472197911574,"score_gpt":0.4538938274257359,"score_spread":0.2945466076345785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322624753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9723485,0.0016377643,0.0186485,0.0002752194,0.00008323283,0.0000955648,0.002881815,0.001213548,0.0028157227],"genre_scores_gemma":[0.9862976,0.00054085965,0.008760438,0.00015510585,0.0000066485773,0.000055970482,0.001933026,0.00008564223,0.002164522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977535,0.00001542387,0.000022524384,0.00008824988,0.00006286217,0.000035688015],"domain_scores_gemma":[0.9998963,0.000025839676,0.000029761884,0.000014590786,0.000011582433,0.000021901214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019309437,0.0003132525,0.00040164505,0.00026405172,0.00018263147,0.00033120316,0.00027583344,0.00043719247,0.0016457904],"category_scores_gemma":[0.00025005583,0.00016381266,0.0003835833,0.00020786724,0.0001949328,0.000094220886,0.00027736326,0.00049193494,0.00048329638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013663853,0.000027205046,0.00089808,0.000074113435,0.000021702004,0.0002689437,0.000016500853,0.0003324526,0.9934089,0.00021650459,0.00026879908,0.004330115],"study_design_scores_gemma":[0.000045378874,0.0002670073,0.011701247,0.000015171258,0.000088510766,0.0013946308,0.00004508357,0.009708786,0.96782166,0.00024283069,0.00864563,0.00002401132],"about_ca_topic_score_codex":0.0011309168,"about_ca_topic_score_gemma":0.0017047648,"teacher_disagreement_score":0.0016457904,"about_ca_system_score_codex":0.00030720897,"about_ca_system_score_gemma":0.00026978663,"threshold_uncertainty_score":0.0055057406},"labels":[],"label_agreement":null},{"id":"W4322624768","doi":"10.1172/jci168070","title":"Chronic pain and premature mortality in men and women, using data from UK Biobank. Reply.","year":2023,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Musculoskeletal pain and rehabilitation","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Biobank; Medicine; Chronic pain; Internal medicine; Physical therapy; Bioinformatics; Biology","score_opus":0.14885249776265558,"score_gpt":0.4212355286330922,"score_spread":0.27238303087043664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322624768","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001862805,0.0014281137,0.00011196068,0.98461086,0.008486575,0.00002390738,0.0020488596,0.00004035373,0.0013865454],"genre_scores_gemma":[0.0090499595,0.0013272096,0.0003279992,0.9694993,0.013265372,0.00015915825,0.0009339235,0.00003196797,0.005405063],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99723876,0.001367851,0.0004689467,0.00031253725,0.000421806,0.00019009964],"domain_scores_gemma":[0.97753716,0.017542643,0.0009924927,0.00065212866,0.0021808492,0.0010947263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0055658906,0.00078165805,0.0013810212,0.0011833468,0.0020642509,0.0021128352,0.0016008742,0.019180141,0.0065236026],"category_scores_gemma":[0.034266733,0.0007719157,0.0010082806,0.0022833212,0.0013267954,0.0023856154,0.0013855129,0.015311372,0.005356509],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015639348,0.000023807494,0.00665908,0.00009813612,0.000044554585,0.0004872716,0.0002641672,0.000045978457,0.00010559551,0.000500117,0.9866071,0.0050078453],"study_design_scores_gemma":[0.0009570786,0.00036220628,0.089775234,0.0025142184,0.00055648974,0.0036704526,0.0057013324,0.0021099248,0.00089943426,0.011569144,0.881453,0.00043152942],"about_ca_topic_score_codex":0.030614447,"about_ca_topic_score_gemma":0.041275706,"teacher_disagreement_score":0.030614447,"about_ca_system_score_codex":0.0016324033,"about_ca_system_score_gemma":0.002721085,"threshold_uncertainty_score":0.060872495},"labels":[],"label_agreement":null},{"id":"W4322758311","doi":"10.1172/jci163627","title":"A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Massachusetts General Hospital; Dr. Miriam and Sheldon G. Adelson Medical Research Foundation; Harrington Discovery Institute, University Hospitals","keywords":"Parathyroid hormone; Endocrinology; Internal medicine; Vitamin D and neurology; Kidney; Calcitriol receptor; Chemistry; Homeostasis; Vitamin; Secondary hyperparathyroidism; Calcium; Biology; Medicine","score_opus":0.09807925881092149,"score_gpt":0.3800781152713157,"score_spread":0.2819988564603942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322758311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9601041,0.012249704,0.017177483,0.00048400188,0.00014254627,0.00008772328,0.0015265248,0.0006256194,0.007602457],"genre_scores_gemma":[0.9911232,0.0024121518,0.0028865943,0.00007638257,0.000024879562,0.000038168437,0.00045793017,0.00003878622,0.0029418576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981815,0.000016263468,0.00001133322,0.0000678823,0.000044783035,0.000041543215],"domain_scores_gemma":[0.9998945,0.000006436404,0.000031724903,0.000011986041,0.00002114092,0.000034262714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121290424,0.00030687643,0.00025820232,0.00026306973,0.00027800683,0.00053892814,0.00019055062,0.00020442308,0.0011117264],"category_scores_gemma":[0.00012611186,0.00016557603,0.0003092389,0.000148866,0.00031487714,0.00026579582,0.00043830017,0.0004394582,0.00035843477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021483777,0.000013700042,0.0016224006,0.00006368453,0.00001454004,0.000066250366,0.000034614644,0.00013534307,0.99140537,0.0005470146,0.00015947508,0.0057227304],"study_design_scores_gemma":[0.00010312039,0.00034484128,0.098418675,0.000031817202,0.000114251794,0.00074315676,0.00019362051,0.005513789,0.8682698,0.0012311923,0.024987722,0.000048048085],"about_ca_topic_score_codex":0.00095694966,"about_ca_topic_score_gemma":0.001151524,"teacher_disagreement_score":0.0011117264,"about_ca_system_score_codex":0.0005497927,"about_ca_system_score_gemma":0.00043886228,"threshold_uncertainty_score":0.003989041},"labels":[],"label_agreement":null},{"id":"W4327574674","doi":"10.1172/jci166647","title":"RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health; DOD Prostate Cancer Research Program; Beth Israel Deaconess Medical Center; School of Medicine, Duke University; U.S. Department of Defense","keywords":"Prostate cancer; Cancer research; Metastasis; Prostate; E2F; Cancer; Biology; Medicine; Internal medicine; Cell cycle","score_opus":0.05225788885575229,"score_gpt":0.33901913911457865,"score_spread":0.2867612502588264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327574674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897848,0.003410604,0.004534655,0.00026556352,0.000030498779,0.000038716185,0.0004723723,0.00022237682,0.0012406082],"genre_scores_gemma":[0.9937782,0.0011243265,0.0018884898,0.000050009865,0.0000060626166,0.000026785234,0.00041466005,0.000022195216,0.002689289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990547,0.000017613645,0.0000068118493,0.000016382952,0.000027063084,0.000026658125],"domain_scores_gemma":[0.9999449,0.0000067091028,0.000017391287,0.0000061529267,0.000006356935,0.000018509276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001332931,0.00041063357,0.00028351415,0.00033936716,0.00017994734,0.00031151946,0.00016853878,0.00024036791,0.0015020531],"category_scores_gemma":[0.000080444304,0.00013988595,0.0002508374,0.00013221937,0.000262997,0.00017678947,0.00017809734,0.00055281393,0.00028438694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000975752,0.000015338257,0.00020046216,0.000017269558,0.0000036381489,0.000046331752,0.0000056118897,0.000034463785,0.99861336,0.000071618364,0.000025942558,0.0008682206],"study_design_scores_gemma":[0.000015126302,0.00021830258,0.004766582,0.0000032512874,0.000013933927,0.0005710469,0.0000251044,0.0005552368,0.9913874,0.00008091189,0.0023582538,0.0000048355605],"about_ca_topic_score_codex":0.00066875905,"about_ca_topic_score_gemma":0.0015440256,"teacher_disagreement_score":0.0015020531,"about_ca_system_score_codex":0.00034260374,"about_ca_system_score_gemma":0.00031998268,"threshold_uncertainty_score":0.00502491},"labels":[],"label_agreement":null},{"id":"W4361190175","doi":"10.1172/jci165019","title":"CERT1 mutations perturb human development by disrupting sphingolipid homeostasis","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Hospital for Sick Children; University of Alberta; University of Victoria; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Vagelos College of Physicians and Surgeons, Columbia University; Children's Health Foundation; Ministero della Salute; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; École Polytechnique Fédérale de Lausanne; National Natural Science Foundation of China; Institut National de la Santé et de la Recherche Médicale; Deutsche Forschungsgemeinschaft; National Institute of Neurological Disorders and Stroke; Narodowym Centrum Nauki; Stiftung für die Erforschung der Muskelkrankheiten; National Institute for Health and Care Research; National Institute of Diabetes and Digestive and Kidney Diseases; Instituto de Salud Carlos III; Simons Foundation Autism Research Initiative; Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu; Wellcome Trust; Stiftelsen Kristian Gerhard Jebsen; National Science Foundation","keywords":"Sphingolipid; Homeostasis; Cell biology; Biology; Mutation; Computational biology; Genetics; Gene","score_opus":0.07409829802251386,"score_gpt":0.38048519157149946,"score_spread":0.30638689354898563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361190175","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99266315,0.0018317486,0.0018215717,0.00018030051,0.000028340037,0.000038417016,0.00043999378,0.00018083883,0.0028156152],"genre_scores_gemma":[0.9964869,0.0009957016,0.0012991525,0.000049130227,0.000013235056,0.000009810858,0.000258083,0.000030101468,0.0008578488],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999007,0.000015107876,0.000010996991,0.000032195327,0.000023682273,0.00001731385],"domain_scores_gemma":[0.99989223,0.000023827513,0.000042030773,0.0000062466083,0.0000072400717,0.00002830127],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000094277864,0.00097131974,0.000308764,0.00043212227,0.00028148902,0.0002090704,0.00016515155,0.0004026612,0.0021967315],"category_scores_gemma":[0.0003606062,0.00013545257,0.00018177964,0.0002737483,0.00051060267,0.00017574841,0.0003650027,0.0003198799,0.00029821336],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058297074,0.00007883581,0.017176496,0.00010263505,0.00007315178,0.023788098,0.00015976232,0.00063460367,0.9311553,0.0006734515,0.00056774676,0.0250069],"study_design_scores_gemma":[0.00012675939,0.0011725447,0.1615183,0.000077305995,0.00022919213,0.17467682,0.00031321472,0.0023936522,0.64447117,0.00094431284,0.014021956,0.00005476805],"about_ca_topic_score_codex":0.0006371427,"about_ca_topic_score_gemma":0.0009527303,"teacher_disagreement_score":0.0021967315,"about_ca_system_score_codex":0.00020878074,"about_ca_system_score_gemma":0.00022254087,"threshold_uncertainty_score":0.007348776},"labels":[],"label_agreement":null},{"id":"W4362509514","doi":"10.1172/jci168595","title":"Seeking neuroprotection in multiple sclerosis: an ongoing challenge","year":2023,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Multiple sclerosis; Neuroprotection; Neuroscience; Medicine; Experimental autoimmune encephalomyelitis; Oligodendrocyte; Inflammation; Disease; Myelin sheath; Demyelinating disease; Demyelinating Disorder; Myelin; Immunology; Bioinformatics; Central nervous system; Biology; Pathology","score_opus":0.4557205031992891,"score_gpt":0.43014328022397713,"score_spread":0.025577222975311953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362509514","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003782226,0.024769297,0.0002570022,0.9585127,0.015074868,0.000008622598,0.000008064732,0.000027814027,0.0009633788],"genre_scores_gemma":[0.007728946,0.06106373,0.0019760681,0.66542,0.25984293,0.00006703933,0.000031313964,0.000035038218,0.0038349628],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.995382,0.0018997648,0.00061267486,0.00031704566,0.0015350778,0.00025342806],"domain_scores_gemma":[0.9816607,0.0106718885,0.00086458283,0.00081274053,0.0037107293,0.0022793738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00663843,0.0006993452,0.002351618,0.0007783893,0.0028677667,0.0042154337,0.0019248191,0.021210812,0.0038167667],"category_scores_gemma":[0.018063402,0.00039776423,0.0008561123,0.00072154216,0.0054779258,0.0077541503,0.0019161078,0.025826111,0.0039994535],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001992805,0.00032135955,0.00062900304,0.00082017196,0.0000437205,0.0028360663,0.00044687296,0.00013035376,0.0014322482,0.017617024,0.80384964,0.17167431],"study_design_scores_gemma":[0.00021551589,0.00028785193,0.00079794857,0.001348801,0.000050273626,0.004149618,0.0013801281,0.00032748212,0.00059085805,0.042125523,0.948655,0.00007096503],"about_ca_topic_score_codex":0.0008285148,"about_ca_topic_score_gemma":0.002120542,"teacher_disagreement_score":0.021210812,"about_ca_system_score_codex":0.0030326839,"about_ca_system_score_gemma":0.004203413,"threshold_uncertainty_score":0.03510773},"labels":[],"label_agreement":null},{"id":"W4362510201","doi":"10.1172/jci168662","title":"Glutamate shall not pass: a mechanistic role for astrocytic O-GlcNAc transferase in stress and depression","year":2023,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canada First Research Excellence Fund; Canadian Institutes of Health Research; Université Laval","keywords":"Glutamatergic; Prefrontal cortex; Antidepressant; Glutamate receptor; Transferase; Neuroscience; Depression (economics); Excitatory postsynaptic potential; Biology; Biochemistry; Hippocampus; Enzyme; Receptor","score_opus":0.06713327157220897,"score_gpt":0.3711085766001823,"score_spread":0.3039753050279733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362510201","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027584387,0.0081690885,0.00034727945,0.9363594,0.049105927,0.000026097923,0.000058394922,0.00007850555,0.0030968064],"genre_scores_gemma":[0.03390719,0.014590102,0.00072854775,0.7594065,0.17806089,0.00007434819,0.000061594976,0.000034972807,0.01313587],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9994112,0.00014089601,0.00009457668,0.00009904937,0.00017750557,0.00007666946],"domain_scores_gemma":[0.998422,0.0007332361,0.0001508488,0.00009651589,0.00032707502,0.00027038596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001233036,0.0006618438,0.00072139263,0.00031635998,0.0013987902,0.0017215902,0.0010757559,0.01701784,0.002202477],"category_scores_gemma":[0.005575963,0.00034509096,0.00066444575,0.00033499033,0.0018791811,0.0018062931,0.0006060968,0.015766785,0.0026033795],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004397499,0.00013864569,0.0014363069,0.00017286226,0.000039780964,0.009751762,0.00013505065,0.00013558958,0.0024284024,0.005966638,0.9439375,0.035417877],"study_design_scores_gemma":[0.0005565518,0.0003600596,0.004820483,0.00033884618,0.00009284022,0.015171804,0.0005379753,0.0016754366,0.0028152992,0.024572192,0.94896066,0.000097877935],"about_ca_topic_score_codex":0.0012087391,"about_ca_topic_score_gemma":0.0017906203,"teacher_disagreement_score":0.01701784,"about_ca_system_score_codex":0.0020563046,"about_ca_system_score_gemma":0.0012380789,"threshold_uncertainty_score":0.014919579},"labels":[],"label_agreement":null},{"id":"W4367320450","doi":"10.1172/jci161453","title":"Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University; Ted Rogers Centre for Heart Research; University Health Network; University of Toronto; Toronto General Hospital; St. Michael's Hospital","funders":"Biotechnology and Biological Sciences Research Council; Heart and Stroke Foundation of Canada; Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; University of Toronto; Diabetes Canada","keywords":"Downregulation and upregulation; Ventricular remodeling; ISG15; Pressure overload; Heart failure; Inflammation; Internal medicine; Endocrinology; Cardiomyopathy; Cell biology; Filamin; Myocyte; Diabetic cardiomyopathy; Ubiquitin; Biology; Chemistry; Medicine; Cell; Biochemistry","score_opus":0.09130328682495234,"score_gpt":0.3491667649176099,"score_spread":0.2578634780926575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367320450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950363,0.0017885371,0.0016251312,0.00019599768,0.000051381518,0.000020521828,0.0001723701,0.000048856728,0.0010608917],"genre_scores_gemma":[0.99723685,0.00059895514,0.00080766925,0.00015707208,0.000017583714,0.000016718172,0.00019397089,0.000009808275,0.00096122065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989164,0.000019275314,0.0000084073445,0.000025274752,0.000024194926,0.000031178144],"domain_scores_gemma":[0.99992,0.0000057935,0.000031656804,0.000007767279,0.000006497651,0.00002815993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016696054,0.00030684716,0.0001910573,0.00019221577,0.00013981047,0.00026717645,0.00012546989,0.00027604445,0.0012999072],"category_scores_gemma":[0.00007892536,0.00009947795,0.00027328855,0.00009248497,0.00028185532,0.00015031722,0.00025025022,0.00041721892,0.00020075767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002083719,0.00002578204,0.0016799205,0.000030447058,0.000012500549,0.00013104668,0.000012541076,0.00003073632,0.99632347,0.00011073114,0.000057371282,0.0013771071],"study_design_scores_gemma":[0.000109336856,0.0012406249,0.15839009,0.000055132597,0.000091062095,0.0016080999,0.00014745639,0.0013878276,0.8297629,0.0005949541,0.0065983078,0.0000142216095],"about_ca_topic_score_codex":0.00018661362,"about_ca_topic_score_gemma":0.00041378444,"teacher_disagreement_score":0.0012999072,"about_ca_system_score_codex":0.00021121006,"about_ca_system_score_gemma":0.00015998865,"threshold_uncertainty_score":0.0043486357},"labels":[],"label_agreement":null},{"id":"W4376643537","doi":"10.1172/jci167824","title":"Back to the future: evolutionary biology reveals a key regulatory switch in neuroblastoma pathogenesis","year":2023,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa; Izaak Walton Killam Health Centre","funders":"Canadian Institutes of Health Research; Killam Trusts","keywords":"Zebrafish; Neuroblastoma; Biology; Gene; Metastasis; Cancer research; Genetics; Cell culture; Cancer","score_opus":0.08392086371767962,"score_gpt":0.38280903520516374,"score_spread":0.29888817148748414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376643537","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001996979,0.005713795,0.00047100006,0.9675565,0.022481373,0.000008466022,0.000035542915,0.00006242879,0.0016740616],"genre_scores_gemma":[0.026679859,0.013763367,0.0012430354,0.8031629,0.1460612,0.000031447264,0.000045990073,0.00003956728,0.008972755],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99928516,0.00022792767,0.00009851726,0.00012294862,0.00018445424,0.00008104628],"domain_scores_gemma":[0.9973853,0.001465539,0.00015584499,0.00012716508,0.0004827791,0.00038342676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014838185,0.0004554201,0.0007030968,0.00043229054,0.0013615659,0.0016528701,0.0009118098,0.012998198,0.0034048301],"category_scores_gemma":[0.0061657857,0.00030579406,0.00060162,0.0003254613,0.0023052865,0.0035792666,0.00076823693,0.01808476,0.0024555658],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025788165,0.00008449918,0.003683039,0.00020567648,0.00004488843,0.010190244,0.00041373222,0.0002531495,0.0031930238,0.0081022065,0.8922315,0.08134016],"study_design_scores_gemma":[0.00015667033,0.00022275245,0.0047955937,0.00038860168,0.00006354484,0.021664558,0.0013309995,0.0014168848,0.0017212222,0.05197554,0.91615474,0.00010896737],"about_ca_topic_score_codex":0.0015043304,"about_ca_topic_score_gemma":0.0024428116,"teacher_disagreement_score":0.012998198,"about_ca_system_score_codex":0.0016777328,"about_ca_system_score_gemma":0.0010206641,"threshold_uncertainty_score":0.012172878},"labels":[],"label_agreement":null},{"id":"W4377094281","doi":"10.1172/jci149310","title":"Atrx deletion impairs CGAS/STING signaling and increases sarcoma response to radiation and oncolytic herpesvirus","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"ATRX; Oncolytic virus; Cancer research; Biology; Telomere; Cancer; Mutation; Gene; Genetics","score_opus":0.05448702553684602,"score_gpt":0.36080234072865763,"score_spread":0.3063153151918116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377094281","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99814093,0.0003554086,0.00071782083,0.00003090993,0.000008531254,0.000015085718,0.00018566239,0.000041285286,0.0005043733],"genre_scores_gemma":[0.9974105,0.0002514359,0.0008286746,0.000015981972,0.0000029311238,0.00002000372,0.0002888834,0.000009524159,0.0011721725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981254,0.000039159262,0.000026620031,0.00003595293,0.000042507058,0.00004327485],"domain_scores_gemma":[0.99986935,0.000024493875,0.000046987778,0.00001655645,0.0000058868327,0.00003679004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001655615,0.00030970183,0.00018733118,0.0003272007,0.000075331925,0.00020862294,0.00015914862,0.00026482297,0.0013508018],"category_scores_gemma":[0.00008692856,0.00014680863,0.00023447137,0.00011873554,0.00023419477,0.0001509282,0.00014318393,0.00051429024,0.00022928428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011461102,0.00004834579,0.00019282276,0.000010759744,0.0000040526825,0.000025454581,0.000008162429,0.00009136507,0.9989177,0.000046957477,0.000016828879,0.0005230645],"study_design_scores_gemma":[0.000020734096,0.0006783689,0.004693496,0.0000051828765,0.000012267781,0.00024959,0.000020124598,0.0010300605,0.99247205,0.000027449621,0.00078807253,0.0000025957581],"about_ca_topic_score_codex":0.00040082957,"about_ca_topic_score_gemma":0.00052286533,"teacher_disagreement_score":0.0013508018,"about_ca_system_score_codex":0.00021314,"about_ca_system_score_gemma":0.00016183534,"threshold_uncertainty_score":0.0045188665},"labels":[],"label_agreement":null},{"id":"W4378901208","doi":"10.1172/jci170643","title":"Two to tango: endothelial cell TMEM16 scramblases drive coagulation and thrombosis","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Phospholipid scramblase; Phosphatidylserine; Thrombus; Coagulation; Platelet; Endothelial stem cell; Thrombosis; Fibrin; Immunology; Cell biology; Platelet activation; Biology; Medicine; Internal medicine; Biochemistry; Phospholipid; In vitro","score_opus":0.07921616306726385,"score_gpt":0.3855916389039084,"score_spread":0.30637547583664454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378901208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72656125,0.08538863,0.03359841,0.07272464,0.026766201,0.0003589453,0.002121597,0.003422101,0.04905822],"genre_scores_gemma":[0.87600094,0.023566222,0.013587085,0.01384178,0.0036527421,0.0001842986,0.0014610989,0.000371068,0.067334756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997768,0.000030957577,0.00003067173,0.00005177738,0.000068317735,0.00004154625],"domain_scores_gemma":[0.9996551,0.000056824498,0.000084857085,0.000037830254,0.000053225667,0.00011204299],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037719033,0.00040913178,0.0003386432,0.00033418045,0.00046393988,0.0011521385,0.00038394093,0.0011698779,0.0041268873],"category_scores_gemma":[0.00047600514,0.00023062609,0.0002722086,0.00013360512,0.00056051975,0.00077735086,0.00038944994,0.0020880238,0.0010460673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011552852,0.00022086294,0.0012881791,0.00041939173,0.000085354324,0.0010732773,0.00019130543,0.0001719323,0.9014115,0.007868247,0.033364695,0.052750025],"study_design_scores_gemma":[0.0003235463,0.0007369335,0.0068356544,0.0001031081,0.00013493026,0.003234817,0.00017238465,0.0022188574,0.6739746,0.0029154052,0.30930844,0.000041365685],"about_ca_topic_score_codex":0.00023650151,"about_ca_topic_score_gemma":0.0005408476,"teacher_disagreement_score":0.0041268873,"about_ca_system_score_codex":0.00044335367,"about_ca_system_score_gemma":0.0003135447,"threshold_uncertainty_score":0.013805807},"labels":[],"label_agreement":null},{"id":"W4380685105","doi":"10.1172/jci168553","title":"Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenues","year":2023,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging","keywords":"Disease; Tau pathology; Clinical trial; Tauopathy; Mechanism (biology); Tau protein; Neuroscience; Medicine; Drug development; Neurodegeneration; Bioinformatics; Psychology; Drug; Alzheimer's disease; Biology; Pathology; Psychiatry","score_opus":0.28050285302383055,"score_gpt":0.4913206773068054,"score_spread":0.21081782428297485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380685105","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003072572,0.99911064,0.000034473516,0.00020235489,0.00015078652,0.0000028465997,0.0000057796374,0.0000038385856,0.0004585768],"genre_scores_gemma":[0.00023389762,0.99901843,0.00008488387,0.00019874102,0.00013752021,0.000004681328,0.000009528858,8.685226e-7,0.0003115209],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99968314,0.00007189371,0.000050047896,0.0000454754,0.00011994777,0.000029421386],"domain_scores_gemma":[0.9995167,0.00024716483,0.00006339308,0.000016245607,0.00011469244,0.00004176487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010828747,0.001225899,0.0019268034,0.0032163481,0.0004124036,0.0014702863,0.001072195,0.001565671,0.0037123584],"category_scores_gemma":[0.0011879032,0.0003000494,0.0006827989,0.002941035,0.00083299616,0.0022868118,0.0008691699,0.0029746508,0.0021782054],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011384463,0.00010241947,0.00012001385,0.027218983,0.00010087094,0.00017359051,0.000107500135,0.00040766763,0.0012216355,0.006578233,0.047116674,0.91673857],"study_design_scores_gemma":[0.000030751482,0.00012304404,0.0006642456,0.0126783,0.00013421259,0.00113113,0.00009337089,0.00008708761,0.0002612104,0.0053907004,0.97938603,0.000019906502],"about_ca_topic_score_codex":0.0012573483,"about_ca_topic_score_gemma":0.0024123772,"teacher_disagreement_score":0.0037123584,"about_ca_system_score_codex":0.0010149427,"about_ca_system_score_gemma":0.0016299186,"threshold_uncertainty_score":0.012419045},"labels":[],"label_agreement":null},{"id":"W4381682806","doi":"10.1172/jci166248","title":"Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institutes of Health; National Institute of General Medical Sciences; Northwestern University; National Cancer Institute; Prostate Cancer Foundation","keywords":"Cell biology; Mitosis; Aurora A kinase; Aurora kinase; Biology; Cancer research; Microtubule; Mitotic catastrophe; Kinase; Aurora inhibitor; Signal transduction; Cell cycle; Cell; Genetics","score_opus":0.042031984336666356,"score_gpt":0.3437467991179001,"score_spread":0.30171481478123374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381682806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864883,0.0075358674,0.0008242601,0.00028202008,0.0000428518,0.000025397112,0.00032566013,0.000094630894,0.004381184],"genre_scores_gemma":[0.997077,0.0011205546,0.00028072996,0.00004271732,0.000012280141,0.000010429975,0.00019313011,0.0000061296532,0.0012570949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987316,0.000029304625,0.00000560133,0.000013742676,0.000036170546,0.00004204212],"domain_scores_gemma":[0.9999441,0.000004820501,0.000015445035,0.0000039374413,0.000008546308,0.000023083174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000074864714,0.00017341545,0.00013602427,0.00022293229,0.00015873366,0.00020382731,0.00007014328,0.00011020637,0.0021976994],"category_scores_gemma":[0.000085987456,0.000079749174,0.00021205109,0.00010007697,0.0001266933,0.00009658935,0.00020550302,0.00031995494,0.0004246973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021978715,0.000039557934,0.004900538,0.000102105296,0.00002596983,0.00033632916,0.000021461707,0.0000928037,0.98726976,0.00028503776,0.00049338746,0.0062133293],"study_design_scores_gemma":[0.0001221274,0.0013493933,0.2674475,0.00004143751,0.0000956995,0.007040202,0.00023835409,0.002914331,0.69114614,0.00032827051,0.02925164,0.000024873641],"about_ca_topic_score_codex":0.0008741853,"about_ca_topic_score_gemma":0.0019217499,"teacher_disagreement_score":0.0021976994,"about_ca_system_score_codex":0.00025257582,"about_ca_system_score_gemma":0.00025213577,"threshold_uncertainty_score":0.007352054},"labels":[],"label_agreement":null},{"id":"W4382893715","doi":"10.1172/jci163333","title":"Net39 protects muscle nuclei from mechanical stress during the pathogenesis of Emery-Dreifuss muscular dystrophy","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; University of California, San Diego; National Institutes of Health; University of Texas Southwestern Medical Center; Canadian Institutes of Health Research; Welch Foundation","keywords":"Muscular dystrophy; Skeletal muscle; Biology; Myopathy; Myocyte; Muscle disorder; Emerin; Contractility; Pathology; Cell biology; Genetics; Anatomy; Medicine; Gene; Endocrinology; Internal medicine; Nuclear protein","score_opus":0.02746087857523786,"score_gpt":0.29063404626953565,"score_spread":0.26317316769429777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382893715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99606067,0.0021735814,0.00093766634,0.00007518156,0.000021051308,0.000013226859,0.00015969426,0.000045163717,0.0005137669],"genre_scores_gemma":[0.9978599,0.00050682336,0.00048871635,0.000023942557,0.0000047093918,0.000015929147,0.00018532357,0.000008145812,0.0009065986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992466,0.0000136959925,0.000009142783,0.000018624578,0.000017597478,0.00001615433],"domain_scores_gemma":[0.99991584,0.0000081264925,0.000031772204,0.0000068322247,0.00000642712,0.000030924082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018248246,0.0003193211,0.00024147831,0.00020055658,0.000119069104,0.00016837334,0.00022922439,0.00034076915,0.0009386023],"category_scores_gemma":[0.00014843624,0.00012050373,0.00011068693,0.00008753112,0.0003011459,0.0002203518,0.00020687644,0.00029545583,0.00022439817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046118704,0.000017279775,0.00052417035,0.00003635737,0.0000063576017,0.00011113107,0.000011532952,0.000038768863,0.99771106,0.000057192938,0.000023453273,0.0010015274],"study_design_scores_gemma":[0.00012259805,0.0014578024,0.044587772,0.00004119307,0.000042447533,0.0018276796,0.00009156059,0.00063338847,0.94804955,0.00018190633,0.0029530567,0.000010882854],"about_ca_topic_score_codex":0.00021495207,"about_ca_topic_score_gemma":0.000491381,"teacher_disagreement_score":0.0009386023,"about_ca_system_score_codex":0.0002449226,"about_ca_system_score_gemma":0.00013820703,"threshold_uncertainty_score":0.003139913},"labels":[],"label_agreement":null},{"id":"W4382893784","doi":"10.1172/jci171431","title":"Biomarkers in acute kidney injury: On the cusp of a new era?","year":2023,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Nephrotoxicity and Medicinal Plants","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"University of Ottawa","keywords":"Acute kidney injury; Medicine; Biomarker; Etiology; Intensive care medicine; Internal medicine; Creatinine; Kidney disease; Nephrology; Pathology; Bioinformatics; Biology","score_opus":0.14233907859359884,"score_gpt":0.4110829690892371,"score_spread":0.26874389049563824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382893784","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026157754,0.03284982,0.0002936587,0.9441442,0.021734042,0.000007850189,0.000021642145,0.000033064025,0.00065412605],"genre_scores_gemma":[0.004767354,0.046393327,0.001319525,0.7211285,0.22401573,0.000030566956,0.00004009625,0.000035780075,0.0022691227],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9907107,0.0032725267,0.0016296618,0.0009872279,0.0029504637,0.00044942496],"domain_scores_gemma":[0.9502377,0.02952945,0.0019459676,0.0018160281,0.012956987,0.0035138712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.011300965,0.0011912578,0.003186095,0.0018846752,0.0024695483,0.0057793283,0.0026262666,0.028108891,0.0039450284],"category_scores_gemma":[0.03758208,0.0007625445,0.0019121851,0.0014076084,0.00759024,0.012581163,0.0022678745,0.042406384,0.0036798252],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023876253,0.00012433006,0.0022781556,0.0006798054,0.00011696292,0.0026516337,0.00029443845,0.00013237112,0.00073282444,0.0090266215,0.87251353,0.11121047],"study_design_scores_gemma":[0.00019371735,0.00024737397,0.0016669875,0.0016643738,0.00013310483,0.008493358,0.0008326088,0.0008004108,0.0006445703,0.04025359,0.94490844,0.00016138927],"about_ca_topic_score_codex":0.0017283617,"about_ca_topic_score_gemma":0.0029345376,"teacher_disagreement_score":0.028108891,"about_ca_system_score_codex":0.0038174342,"about_ca_system_score_gemma":0.0027542661,"threshold_uncertainty_score":0.059765935},"labels":[],"label_agreement":null},{"id":"W4384627195","doi":"10.1172/jci171554","title":"The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Maple Leaf Medical Clinic","funders":"National Institute of General Medical Sciences; Center for AIDS Research, University of Washington; National Institutes of Health; Center for AIDS Research, Johns Hopkins University; Philadelphia Foundation; Bill and Melinda Gates Foundation; Johns Hopkins University; Delaney AIDS Research Enterprise; NIH Office of the Director; U.S. Department of Energy; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute","keywords":"Antiretroviral therapy; Viral replication; Biology; Virology; Human immunodeficiency virus (HIV); DNA replication; Viral load; DNA; Immunology; Virus; Genetics","score_opus":0.09817220153950623,"score_gpt":0.38694240138840014,"score_spread":0.2887701998488939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384627195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963084,0.0018903578,0.00053226616,0.00012652433,0.00000948823,0.000008059501,0.00013818155,0.000021592918,0.0009651583],"genre_scores_gemma":[0.9988194,0.00021676664,0.00019046344,0.00005654534,0.000017062168,0.000008504881,0.000156494,0.000008007767,0.0005267297],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99952924,0.000082520346,0.00003888228,0.00007516673,0.00016065939,0.00011367442],"domain_scores_gemma":[0.998531,0.00037920944,0.00044959175,0.0001985113,0.00023283098,0.00020889174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065323815,0.000121489626,0.00048674742,0.00021387471,0.00020151288,0.0007346565,0.0002494384,0.0004109171,0.0012088605],"category_scores_gemma":[0.0029539426,0.00023470802,0.00014256257,0.0001884879,0.0002560887,0.0006408613,0.00026820652,0.0006584615,0.00029308768],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021027972,0.0005796311,0.5044433,0.00020067708,0.00019321761,0.00066373,0.0009724459,0.00068777375,0.3921999,0.0008455269,0.0009392732,0.09617171],"study_design_scores_gemma":[0.00008355077,0.0032339278,0.9184856,0.00007911982,0.00022435127,0.0043040235,0.0004720738,0.0026676685,0.06496886,0.0006092268,0.004837891,0.000033786484],"about_ca_topic_score_codex":0.0005545188,"about_ca_topic_score_gemma":0.00048234005,"teacher_disagreement_score":0.0012088605,"about_ca_system_score_codex":0.00026943858,"about_ca_system_score_gemma":0.00029549163,"threshold_uncertainty_score":0.004044056},"labels":[],"label_agreement":null},{"id":"W4384922338","doi":"10.1172/jci164599","title":"Tumors produce glucocorticoids by metabolite recycling, not synthesis, and activate Tregs to promote growth","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Metabolite; Chemistry; Cancer research; Pharmacology; Biochemistry; Biology","score_opus":0.08880090991125407,"score_gpt":0.37482790206814354,"score_spread":0.2860269921568895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384922338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97795266,0.00711209,0.008009861,0.00045977885,0.00020238635,0.000064221866,0.00039776243,0.00037980863,0.0054215277],"genre_scores_gemma":[0.99316436,0.0014654084,0.0021316383,0.00012158097,0.000078704485,0.00002709598,0.0001735934,0.000025289106,0.002812275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998894,0.000023502325,0.0000063955654,0.000019965008,0.000028787306,0.00003186069],"domain_scores_gemma":[0.9999076,0.000013348433,0.000021941707,0.000016171241,0.000008800456,0.000032058535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011269869,0.00024817637,0.00020660974,0.00018118507,0.000097827935,0.00028007556,0.00008610454,0.00015026148,0.0013060961],"category_scores_gemma":[0.00012656869,0.000078737954,0.0001793521,0.00008096285,0.00013796554,0.00012879509,0.00016362705,0.00052794215,0.0004033529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017794725,0.000051823696,0.0009531464,0.000048287773,0.0000062040613,0.00008775103,0.00002366436,0.000080676,0.9871933,0.00024888592,0.00019691218,0.01093137],"study_design_scores_gemma":[0.00008848371,0.0012286915,0.01364823,0.000022617562,0.000036763846,0.0011216523,0.00010115571,0.0012374995,0.9651298,0.0005504461,0.01682501,0.0000096128015],"about_ca_topic_score_codex":0.0002214791,"about_ca_topic_score_gemma":0.0004583769,"teacher_disagreement_score":0.0013060961,"about_ca_system_score_codex":0.00012247506,"about_ca_system_score_gemma":0.0001723259,"threshold_uncertainty_score":0.0043693185},"labels":[],"label_agreement":null},{"id":"W4384926342","doi":"10.1172/jci165370","title":"Cell-free, high-density lipoprotein–specific phospholipid efflux assay predicts incident cardiovascular disease","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"NIH Clinical Center; Department of Medicine, Georgetown University; National Institutes of Health; NHLBI Division of Intramural Research; McGill University; McGill University Health Centre; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Hjärt-Lungfonden; Karolinska Institutet; Georgetown University; George Washington University; AstraZeneca","keywords":"Phospholipid; Disease; Cholesterol; Tangier disease; High-density lipoprotein; Lipoprotein; Efflux; Reverse cholesterol transport; Cell; Chemistry; ABCA1; Medicine; Biochemistry; Internal medicine; Membrane","score_opus":0.053473355394074606,"score_gpt":0.31273144003463843,"score_spread":0.2592580846405638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384926342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974177,0.0006288492,0.0010018443,0.000033019533,0.000012760296,0.000017036158,0.00037828664,0.000031044612,0.00047953628],"genre_scores_gemma":[0.99823916,0.00012922139,0.0007527289,0.00003119982,0.000014053018,0.000015484584,0.0005816122,0.0000027456977,0.0002338358],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99937004,0.00022394034,0.0000721152,0.00013417169,0.00014909806,0.000050679613],"domain_scores_gemma":[0.9979032,0.0006344328,0.00066146,0.00021173732,0.00037664184,0.00021254252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012737275,0.00046807813,0.00033037565,0.000625914,0.00018742892,0.0006487948,0.00033729154,0.000498663,0.001049675],"category_scores_gemma":[0.0023425783,0.00023937305,0.00021054554,0.0004258038,0.00019686848,0.00027754655,0.0002934562,0.00061569543,0.0003206154],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004361316,0.0001178313,0.99195355,0.000020259395,0.00011592918,0.000018433375,0.000017118662,0.00012682124,0.0043104724,0.000016824291,0.0001221607,0.0027444207],"study_design_scores_gemma":[0.00004015314,0.00049671845,0.99250996,0.000006521337,0.00013988638,0.0003707762,0.000033110846,0.0019516402,0.0041448646,0.000051794454,0.00024417636,0.000010248687],"about_ca_topic_score_codex":0.000650094,"about_ca_topic_score_gemma":0.0010466096,"teacher_disagreement_score":0.0012737275,"about_ca_system_score_codex":0.0001477818,"about_ca_system_score_gemma":0.00019027956,"threshold_uncertainty_score":0.0067361593},"labels":[],"label_agreement":null},{"id":"W4385232871","doi":"10.1172/jci166275","title":"Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Astellas Pharma US; Hospital for Sick Children; Astellas Pharma; Audentes Therapeutics","keywords":"Medicine; Pathology","score_opus":0.07087734435940388,"score_gpt":0.33822137069501473,"score_spread":0.26734402633561083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385232871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909779,0.0015373531,0.004318651,0.00046159097,0.0000971675,0.000115831506,0.00073846494,0.00018322741,0.0015698097],"genre_scores_gemma":[0.9855267,0.0015957416,0.0045071878,0.00015276423,0.000024050394,0.0001444264,0.0008401372,0.00005558192,0.0071534934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973744,0.00003906971,0.000039921564,0.000060635975,0.00006901651,0.0000539272],"domain_scores_gemma":[0.9998036,0.00002345732,0.0000627295,0.000015840624,0.000016209131,0.00007821247],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023987843,0.0008456414,0.00040611465,0.0007175954,0.00040043067,0.00026799232,0.0003539567,0.0008139477,0.0017261131],"category_scores_gemma":[0.00017109516,0.00021844963,0.0004569771,0.00018515089,0.0005239804,0.00033763997,0.00038772426,0.0009797463,0.00040638592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014115762,0.00006618991,0.0003346791,0.000058167414,0.000010107682,0.00052752433,0.000033691533,0.000084587984,0.9976526,0.00018512699,0.00010074985,0.00080539525],"study_design_scores_gemma":[0.00011212812,0.0015485683,0.009204279,0.00003650746,0.000089417474,0.002571141,0.00014452619,0.0028905622,0.97782934,0.0001976705,0.0053517986,0.000024064737],"about_ca_topic_score_codex":0.0013798296,"about_ca_topic_score_gemma":0.0025435875,"teacher_disagreement_score":0.0017261131,"about_ca_system_score_codex":0.00049470883,"about_ca_system_score_gemma":0.00037640566,"threshold_uncertainty_score":0.0057744384},"labels":[],"label_agreement":null},{"id":"W4385302461","doi":"10.1172/jci168597","title":"Genetic modification of inflammation- and clonal hematopoiesis–associated cardiovascular risk","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Human Genome Research Institute; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Ludwig Center at Harvard; Genentech; National Institutes of Health; XBiotech; Burroughs Wellcome Fund; Ludwig Institute for Cancer Research; NIH Office of the Director; Japan Society for the Promotion of Science; Boston Scientific Corporation; Novo Nordisk; Massachusetts General Hospital; Celgene; Eli Lilly and Company; AstraZeneca; Knut och Alice Wallenbergs Stiftelse; Fondation Leducq; National Institute of Diabetes and Digestive and Kidney Diseases; Stanley Center for Psychiatric Research, Broad Institute; Amgen","keywords":"Inflammasome; Biology; Inflammation; AIM2; Gene; Gene expression; Genetics; Haematopoiesis; Immunology; Cancer research; Bioinformatics; Stem cell","score_opus":0.0974407511545383,"score_gpt":0.38314511979098087,"score_spread":0.28570436863644255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385302461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838734,0.00010846416,0.000976521,0.000013017058,0.0000017061463,0.0000066397756,0.00035747446,0.000010444817,0.00013857783],"genre_scores_gemma":[0.9989561,0.000039421302,0.0006494533,0.000013180528,0.0000015386183,0.0000073591364,0.00015753206,0.0000041470735,0.00017126676],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997645,0.00007879395,0.000013024315,0.000080240825,0.00003805063,0.000025494995],"domain_scores_gemma":[0.99960023,0.00014340064,0.00014401079,0.00004621317,0.00001868235,0.00004741455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027796815,0.00018268806,0.00015311937,0.0003604134,0.00011160178,0.00028635867,0.00011854412,0.00022422966,0.0021491752],"category_scores_gemma":[0.0008684542,0.00009386853,0.0001386282,0.0002813943,0.0001839999,0.00007933033,0.00027303956,0.00022721791,0.00009598701],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021948756,0.000085273256,0.5820736,0.0001091517,0.00029374435,0.00050074543,0.00021809603,0.0017358531,0.39415982,0.0007507143,0.00028959592,0.017588342],"study_design_scores_gemma":[0.000034869598,0.00047388248,0.96018946,0.000016943013,0.00011623477,0.0011513325,0.000080675265,0.00348169,0.032701213,0.00052094006,0.0012147698,0.000017981163],"about_ca_topic_score_codex":0.00054273586,"about_ca_topic_score_gemma":0.00081620243,"teacher_disagreement_score":0.0021491752,"about_ca_system_score_codex":0.00014475426,"about_ca_system_score_gemma":0.00010057638,"threshold_uncertainty_score":0.007189691},"labels":[],"label_agreement":null},{"id":"W4385737830","doi":"10.1172/jci168601","title":"Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes in mice","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Breakthrough T1D Canada; National Institute of Allergy and Infectious Diseases; BC Children's Hospital; University of Minnesota; National Institutes of Health; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"NOD mice; Immunology; Adoptive cell transfer; Nod; Antigen; Insulitis; Biology; T cell; Cancer research; Immune system; Autoimmunity; Endocrinology; Diabetes mellitus","score_opus":0.049638271726872775,"score_gpt":0.3159860001277476,"score_spread":0.2663477284008748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385737830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97242415,0.0025630968,0.015328073,0.0006255038,0.0003739685,0.00035024076,0.0010347165,0.0016407731,0.005659544],"genre_scores_gemma":[0.975094,0.001516625,0.010826769,0.00047661734,0.00010994916,0.00036185037,0.001051932,0.00025378994,0.010308443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995353,0.00008255532,0.000048009562,0.00009412141,0.00010232999,0.00013763887],"domain_scores_gemma":[0.9997073,0.0000394115,0.00008498219,0.000042244123,0.0000235942,0.00010248501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043562808,0.00079085596,0.0006199228,0.0007143482,0.00024592338,0.00047372223,0.00041759515,0.0008322456,0.0017637543],"category_scores_gemma":[0.00017720937,0.0003960444,0.00046116777,0.00019348529,0.00038524522,0.00035353546,0.0002561678,0.002284774,0.0008263714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046306817,0.0006307978,0.00015578627,0.000052140967,0.000010728789,0.000051418738,0.000022719345,0.0001322572,0.99539053,0.00035022772,0.0002377118,0.0025026961],"study_design_scores_gemma":[0.0003571517,0.0027618515,0.0020832147,0.00003374777,0.000043962784,0.00039181247,0.000027201844,0.0029869245,0.9849889,0.00021949928,0.0060934005,0.000012314948],"about_ca_topic_score_codex":0.00042701775,"about_ca_topic_score_gemma":0.0008365717,"teacher_disagreement_score":0.0017637543,"about_ca_system_score_codex":0.00029526604,"about_ca_system_score_gemma":0.00042262327,"threshold_uncertainty_score":0.005900383},"labels":[],"label_agreement":null},{"id":"W4385741022","doi":"10.1172/jci169823","title":"Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Cancer Institute; Pfizer Canada; Allos Therapeutics; Genentech; National Institutes of Health; Celldex Therapeutics; Astellas Pharma; Eisai; Memorial Sloan-Kettering Cancer Center; Geoffrey Beene Cancer Research Center; Fundación Alfonso Martín Escudero; Pfizer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb; Daiichi Sankyo Europe; U.S. Department of Defense","keywords":"Head and neck squamous-cell carcinoma; Medicine; Blockade; Immune checkpoint; Oncology; Internal medicine; Adverse effect; Head and neck cancer; Head and neck; Disease; Cancer; Surgery; Receptor","score_opus":0.09400576823591318,"score_gpt":0.39880115054653764,"score_spread":0.3047953823106245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385741022","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99939823,0.00010975109,0.00016538214,0.000021294794,0.0000011027137,0.000005447234,0.00018251048,0.000002705213,0.0001136684],"genre_scores_gemma":[0.9996871,0.000016725447,0.00007093271,0.00000879318,0.000001523817,0.0000028272036,0.00019231117,0.0000011169055,0.00001874691],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99981886,0.000050462528,0.00001758364,0.000051559102,0.000028874412,0.0000326645],"domain_scores_gemma":[0.99940026,0.00023366077,0.0002036015,0.0000329947,0.00006162071,0.00006787399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034857003,0.0001535618,0.00022795307,0.00038658507,0.00024412596,0.0002952697,0.00017835018,0.00024600688,0.0010195635],"category_scores_gemma":[0.001240484,0.000070192466,0.00019874812,0.00040410378,0.00024697208,0.00014094463,0.00023195983,0.00022902798,0.00013054069],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039795207,0.000039981165,0.9866996,0.000017666891,0.00005893638,0.00011377958,0.000046721507,0.00092121965,0.0056502246,0.000037751885,0.000106324616,0.0059098364],"study_design_scores_gemma":[0.000007505027,0.00010972346,0.99572796,0.0000037548314,0.000028439685,0.00026077084,0.0000897149,0.002629012,0.00087490486,0.00013075194,0.00013457415,0.0000027459462],"about_ca_topic_score_codex":0.0020635966,"about_ca_topic_score_gemma":0.003544022,"teacher_disagreement_score":0.0020635966,"about_ca_system_score_codex":0.00030556764,"about_ca_system_score_gemma":0.0002038864,"threshold_uncertainty_score":0.004103124},"labels":[],"label_agreement":null},{"id":"W4385741569","doi":"10.1172/jci162120","title":"Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer’s disease phenotype in mice","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital; Western University; University of Windsor","funders":"","keywords":"Hippocampal formation; Cognition; Disease; Oxidative stress; Phenotype; Microinjection; Reductase; Alzheimer's disease; Biology; Neuroscience; Gene; Medicine; Enzyme; Genetics; Cell biology; Biochemistry; Internal medicine","score_opus":0.07181842405704446,"score_gpt":0.358132448356502,"score_spread":0.2863140242994575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385741569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.978233,0.004628971,0.010136405,0.0006543297,0.0002090161,0.00016664185,0.0016243136,0.0011404814,0.003206887],"genre_scores_gemma":[0.9734403,0.0043809297,0.008651534,0.0003699774,0.00006959278,0.00025893253,0.0016450403,0.00017821611,0.011005399],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981755,0.000025857164,0.000021288619,0.000043065138,0.000040250372,0.00005197194],"domain_scores_gemma":[0.99983037,0.0000132378755,0.000058595648,0.00001859168,0.000022720118,0.000056428536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028713178,0.0007154227,0.00064317446,0.00049077923,0.00016792536,0.0003523012,0.00041048953,0.0005363214,0.0017468061],"category_scores_gemma":[0.0001294248,0.00025402437,0.00037493123,0.0001791369,0.00032257917,0.00033076582,0.0001650206,0.0011124902,0.00051920634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009234131,0.0003690747,0.00015964362,0.00007036935,0.000021782469,0.000032346306,0.00001912902,0.00007364384,0.99331963,0.0001599176,0.00022869051,0.004622383],"study_design_scores_gemma":[0.00024397882,0.0033269664,0.002904833,0.000014037587,0.000071483184,0.0001662852,0.000032545682,0.0008520686,0.98729545,0.00013891527,0.004942718,0.000010708903],"about_ca_topic_score_codex":0.00080546393,"about_ca_topic_score_gemma":0.001879954,"teacher_disagreement_score":0.0017468061,"about_ca_system_score_codex":0.00026288567,"about_ca_system_score_gemma":0.00034720925,"threshold_uncertainty_score":0.0058436394},"labels":[],"label_agreement":null},{"id":"W4385835251","doi":"10.1172/jci167053","title":"RUNX1 loss renders hematopoietic and leukemic cells dependent on IL-3 and sensitive to JAK inhibition","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Stanford Bio-X; Nakayama Foundation for Human Science; Alex's Lemonade Stand Foundation for Childhood Cancer; School of Medicine, Stanford University; American Society of Hematology; Ludwig Center at Harvard; National Institutes of Health; National Science Foundation","keywords":"RUNX1; Haematopoiesis; Cancer research; Biology; Leukemia; Immunology; Stem cell; Cell biology","score_opus":0.07849238685559991,"score_gpt":0.3869725904824171,"score_spread":0.3084802036268172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385835251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99388677,0.0006844962,0.00217955,0.00015191427,0.000034138797,0.000059407193,0.0011402075,0.00017351253,0.0016901656],"genre_scores_gemma":[0.9951857,0.00033102566,0.0012121188,0.000045708577,0.00000843704,0.000046599165,0.0009866653,0.000036642265,0.002147228],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997558,0.00003638192,0.0000298086,0.000037481288,0.000081816004,0.0000587494],"domain_scores_gemma":[0.9998635,0.000029229177,0.000035331977,0.00002347784,0.000007265767,0.000041194202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016201923,0.0003419239,0.00030600696,0.0003417305,0.00017736625,0.00047615333,0.00019903143,0.0002559398,0.0020509486],"category_scores_gemma":[0.00012564685,0.00016756597,0.0002693438,0.00020052673,0.00032975478,0.00017352628,0.00023009829,0.00088908616,0.00046484492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017424836,0.000056891637,0.00022027119,0.000016117514,0.0000051892466,0.00009148216,0.000015647945,0.00013351208,0.9978922,0.0002624701,0.00008525245,0.0010466939],"study_design_scores_gemma":[0.000028582033,0.00022902958,0.0031382558,0.000004384426,0.000012701599,0.00040024574,0.000030074278,0.0011176625,0.99191916,0.00007662442,0.003039659,0.0000035742896],"about_ca_topic_score_codex":0.0007554219,"about_ca_topic_score_gemma":0.0015943014,"teacher_disagreement_score":0.0020509486,"about_ca_system_score_codex":0.0003068027,"about_ca_system_score_gemma":0.00035656878,"threshold_uncertainty_score":0.0068610907},"labels":[],"label_agreement":null},{"id":"W4385840249","doi":"10.1172/jci167517","title":"Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; European Commission; National Human Genome Research Institute; American Heart Association","keywords":"Inflammasome; Atrial fibrillation; Kidney disease; Medicine; Kidney; Internal medicine; Cardiology; Pharmacology; Inflammation","score_opus":0.1299424610619286,"score_gpt":0.3986886791641275,"score_spread":0.2687462181021989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385840249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95994335,0.025771642,0.005732003,0.0015529079,0.00033462967,0.00014916078,0.0007405677,0.00017719837,0.0055984184],"genre_scores_gemma":[0.9872111,0.007911541,0.0020311938,0.00066813163,0.00017095714,0.00016083645,0.00045868196,0.000013406471,0.0013742446],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999634,0.000093932795,0.000054165044,0.000060219063,0.00008009519,0.00007751418],"domain_scores_gemma":[0.9996953,0.000037891277,0.00013482267,0.000021271851,0.000038580147,0.00007220337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045646142,0.0002786498,0.0005234283,0.00031979207,0.00023926399,0.0005193784,0.00013144765,0.00043673138,0.0021951662],"category_scores_gemma":[0.00038679835,0.00017796204,0.0007593547,0.00021678016,0.000298729,0.00032466574,0.0005663003,0.0011696856,0.00025714686],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004787821,0.0007979884,0.035728723,0.0020832568,0.00044322122,0.0030145538,0.00053599785,0.00041071163,0.91023755,0.0018461653,0.002925455,0.03718849],"study_design_scores_gemma":[0.0015805677,0.0073875515,0.7274563,0.00074704434,0.00095590897,0.017906133,0.0010321193,0.005640366,0.18231854,0.0076522063,0.04717614,0.00014718034],"about_ca_topic_score_codex":0.000209381,"about_ca_topic_score_gemma":0.0003726013,"teacher_disagreement_score":0.0021951662,"about_ca_system_score_codex":0.00015232919,"about_ca_system_score_gemma":0.0003171131,"threshold_uncertainty_score":0.0073435903},"labels":[],"label_agreement":null},{"id":"W4386083973","doi":"10.1172/jci168192","title":"HDAC11 inhibition triggers bimodal thermogenic pathways to circumvent adipocyte catecholamine resistance","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"NHLBI Division of Intramural Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Eikonizo Therapeutics; Italfarmaco; National Jewish Health; American Heart Association","keywords":"Thermogenin; Adipocyte; Cell biology; Biology; Thermogenesis; Signal transduction; Adipose tissue; Endocrinology","score_opus":0.117522494726675,"score_gpt":0.3792125601357577,"score_spread":0.2616900654090827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386083973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99029255,0.0019496498,0.0042230194,0.00016241062,0.000109953755,0.000045513516,0.00080150063,0.00021759137,0.0021978067],"genre_scores_gemma":[0.9940626,0.0010690491,0.0015119578,0.000073789786,0.000016114856,0.000042621334,0.000638944,0.000032119082,0.0025527687],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987924,0.0000114020495,0.000012949697,0.000031628777,0.00002492449,0.00003980386],"domain_scores_gemma":[0.99994123,0.000006992036,0.000019463061,0.000008654672,0.0000041858443,0.000019482744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009429603,0.00036923922,0.00026738262,0.00013225191,0.00010445977,0.00024571994,0.00021016705,0.00020248938,0.0014087724],"category_scores_gemma":[0.00005555479,0.00013694295,0.00032505134,0.00009709707,0.00022890398,0.00014385862,0.00018399516,0.00066520885,0.0003677508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016582858,0.000024398722,0.00014408412,0.000025962498,0.00000738443,0.000023876546,0.000005972525,0.00004430489,0.9983254,0.00010160223,0.000051095773,0.00108019],"study_design_scores_gemma":[0.000022140497,0.0003094937,0.0023918936,0.0000034165432,0.00001552222,0.0001057396,0.000014655024,0.00039898913,0.9947443,0.000026524218,0.0019641959,0.0000031663378],"about_ca_topic_score_codex":0.00039348498,"about_ca_topic_score_gemma":0.0010020398,"teacher_disagreement_score":0.0014087724,"about_ca_system_score_codex":0.00023429615,"about_ca_system_score_gemma":0.0001484892,"threshold_uncertainty_score":0.0047128797},"labels":[],"label_agreement":null},{"id":"W4386117018","doi":"10.1172/jci170341","title":"Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Institute on Minority Health and Health Disparities; National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University; University of Texas Health Science Center at San Antonio; Perelman School of Medicine, University of Pennsylvania; Centers for Disease Control and Prevention; National Institutes of Health; George Institute for Global Health; Idorsia Pharmaceuticals; University of Pennsylvania; Novo Nordisk; Bristol-Myers Squibb; Cleveland Clinic; Rijksuniversiteit Groningen; Maze Therapeutics; University of California, San Francisco; Horizon Pharma; Deutsches Krebsforschungszentrum; Johns Hopkins University; Eidgenössische Technische Hochschule Zürich; National University of Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University; Michigan Institute for Clinical and Health Research; Eli Lilly and Company; Kaiser Permanente; Georgia Clinical and Translational Science Alliance; Gilead Sciences; Boettcher Foundation; Pacific Northwest National Laboratory; Universitair Medisch Centrum Groningen; University of Colorado School of Medicine, Anschutz Medical Campus; University of Illinois at Urbana-Champaign; European Molecular Biology Laboratory; CSL Behring; AstraZeneca; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi; American Heart Association; American Diabetes Association","keywords":"Medicine; Kidney disease; Albuminuria; Diabetes mellitus; Diabetic nephropathy; Kidney; Internal medicine; Endocrinology; Renal function; Biomarker; Microalbuminuria; PI3K/AKT/mTOR pathway; Biology; Apoptosis","score_opus":0.06025230152040864,"score_gpt":0.32870586562594956,"score_spread":0.2684535641055409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386117018","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99069536,0.0045223436,0.0013201901,0.00034720168,0.000069142545,0.000029867271,0.0010359831,0.000051109568,0.0019288551],"genre_scores_gemma":[0.9965423,0.0011409966,0.0007255632,0.00016832894,0.000028254455,0.000024498011,0.0006233534,0.000005135096,0.0007415085],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9996536,0.000105120555,0.000030250449,0.00006968038,0.00008350035,0.00005782141],"domain_scores_gemma":[0.99966073,0.000030198724,0.00014019242,0.000045804474,0.000041913343,0.000081137456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007630141,0.00042879442,0.0005525532,0.00077046274,0.00030503352,0.0010148305,0.00032403556,0.00044194836,0.0016164529],"category_scores_gemma":[0.00051999686,0.00020321643,0.00052661006,0.0008828797,0.0002916413,0.00038680993,0.00062100386,0.0009413823,0.0002376081],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024903912,0.0027660069,0.81452066,0.00055444415,0.0011070365,0.00096545747,0.00022841831,0.0014922811,0.09782708,0.001110971,0.0022633846,0.05226045],"study_design_scores_gemma":[0.0003758497,0.0030101072,0.945827,0.00012475369,0.0009772815,0.0018048417,0.00046198463,0.0073822043,0.033001706,0.0018347751,0.005123476,0.00007611653],"about_ca_topic_score_codex":0.0018692698,"about_ca_topic_score_gemma":0.0024432507,"teacher_disagreement_score":0.0018692698,"about_ca_system_score_codex":0.00043206438,"about_ca_system_score_gemma":0.00043890832,"threshold_uncertainty_score":0.005407572},"labels":[],"label_agreement":null},{"id":"W4386117213","doi":"10.1172/jci166644","title":"Peroxisome disruption alters lipid metabolism and potentiates antitumor response with MAPK-targeted therapy in melanoma","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; McGill University Health Centre; Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research; McGill University; Massachusetts General Hospital","keywords":"Biology; Melanoma; Cancer research; Lipid metabolism; Biogenesis; Peroxisome; Cell biology; Biochemistry; Gene","score_opus":0.04409990182193112,"score_gpt":0.33180167152671497,"score_spread":0.28770176970478384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386117213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99830925,0.0005222486,0.000350685,0.000034171546,0.000015663267,0.000024192164,0.00006412801,0.00003603845,0.0006434872],"genre_scores_gemma":[0.99814653,0.00040711203,0.00045686596,0.000018478435,0.000006917595,0.000023458944,0.00012955637,0.00000848294,0.0008026667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999083,0.000022258897,0.000008172129,0.000013475415,0.000019223646,0.00002854378],"domain_scores_gemma":[0.9999571,0.000008202668,0.00000899509,0.0000069848957,0.0000038506664,0.000014980318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010981675,0.00026431723,0.0003194386,0.00020499398,0.00012621917,0.00020051909,0.0001088063,0.00017908738,0.00091839174],"category_scores_gemma":[0.00007930757,0.00009528771,0.00015099873,0.00013375553,0.00014875973,0.00013614664,0.0001400839,0.000593038,0.00021222807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003690735,0.00016292457,0.000200372,0.000017150047,0.0000051336133,0.00003408675,0.000014191377,0.00008536479,0.9964987,0.000039263512,0.000033480217,0.0025402824],"study_design_scores_gemma":[0.00006242824,0.0040792753,0.0056405594,0.0000045159427,0.000029896433,0.0003330179,0.000026281827,0.0008719035,0.98709595,0.00003927287,0.0018125765,0.0000042738634],"about_ca_topic_score_codex":0.0002893986,"about_ca_topic_score_gemma":0.0006665778,"teacher_disagreement_score":0.00091839174,"about_ca_system_score_codex":0.00017804062,"about_ca_system_score_gemma":0.00014731176,"threshold_uncertainty_score":0.0030723214},"labels":[],"label_agreement":null},{"id":"W4386325060","doi":"10.1172/jci171723","title":"Effects of AFQ056 on language learning in fragile X syndrome","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Shionogi; Azrieli Foundation; Zynerba Pharmaceuticals; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Fragile X Foundation; Biogen; National Institute of Neurological Disorders and Stroke; Massachusetts General Hospital; China Scholarship Council; Novartis; University of California, Davis; F. Hoffmann-La Roche; FRAXA Research Foundation; Ultragenyx Pharmaceutical; Autism Speaks","keywords":"Fragile X syndrome; Computer science; Medicine; Biology; Genetics","score_opus":0.024224364192408615,"score_gpt":0.33062507154164256,"score_spread":0.30640070734923397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386325060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99561393,0.0031073657,0.00018178351,0.0002446622,0.00006582086,0.00015688618,0.00010182816,0.000035997477,0.0004916102],"genre_scores_gemma":[0.9962782,0.0020383352,0.00057682284,0.00022490474,0.00006143454,0.0002626621,0.00011090672,0.000004239003,0.00044243925],"study_design_codex":"randomized_trial","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995896,0.0002401481,0.00003548744,0.000049092516,0.000039490984,0.000046149256],"domain_scores_gemma":[0.9995559,0.00015007368,0.00012322917,0.000022662534,0.000027550268,0.00012067871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012125849,0.00068302534,0.00091384887,0.0002741628,0.00026700535,0.00027711346,0.00043179077,0.00064929837,0.0025122794],"category_scores_gemma":[0.0010254341,0.00012860463,0.0006435767,0.00010737004,0.00059610856,0.00031887935,0.0002996212,0.00086852704,0.0001968086],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.5616657,0.030182483,0.007855137,0.002749579,0.0014833998,0.00040148626,0.00033795057,0.001142148,0.059014067,0.0005676253,0.0016637191,0.33293658],"study_design_scores_gemma":[0.2486948,0.70230854,0.025588721,0.00023255605,0.000853391,0.00046198684,0.00018150388,0.001136098,0.01759776,0.000513724,0.0023915085,0.00003933815],"about_ca_topic_score_codex":0.00072588614,"about_ca_topic_score_gemma":0.0017940302,"teacher_disagreement_score":0.0025122794,"about_ca_system_score_codex":0.000404382,"about_ca_system_score_gemma":0.00044452993,"threshold_uncertainty_score":0.008404374},"labels":[],"label_agreement":null},{"id":"W4386525605","doi":"10.1172/jci170420","title":"Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 mismatches associated with kidney transplant survival","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Natera; National Center for Advancing Translational Sciences; CSL Behring; National Institutes of Health; Alexion Pharmaceuticals","keywords":"Biology; Expression quantitative trait loci; Human leukocyte antigen; Single-nucleotide polymorphism; Haplotype; Genome-wide association study; Genetics; Allele; Locus (genetics); SNP; Gene; Genotype; Antigen","score_opus":0.0813089496246744,"score_gpt":0.35245922644358246,"score_spread":0.2711502768189081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386525605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992422,0.000059106602,0.00037308494,0.000015326299,0.0000014622525,0.0000018806246,0.0001554978,0.000012395527,0.00013917587],"genre_scores_gemma":[0.99953437,0.000012403587,0.00016759653,0.000014878498,0.0000021882504,0.0000030155236,0.00016761235,0.000006240979,0.0000916932],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99969435,0.000070189315,0.000024029525,0.00013030203,0.00003690022,0.000044193523],"domain_scores_gemma":[0.9993179,0.00020751733,0.00028724287,0.00006949614,0.000032704847,0.000085137246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039598945,0.00013719873,0.00025099478,0.00045803664,0.00014382282,0.00032942236,0.00019925606,0.00021693732,0.0020704523],"category_scores_gemma":[0.0009929716,0.0001018966,0.0002738193,0.00041522374,0.00022134652,0.00012460678,0.00030176525,0.0002788034,0.00020407545],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014694028,0.00006374782,0.90218705,0.0000440837,0.00031247403,0.00039654525,0.000240078,0.00082011236,0.0835906,0.00029530723,0.00030251208,0.010278106],"study_design_scores_gemma":[0.000011483998,0.00010268103,0.99440587,0.0000038782177,0.00007910345,0.00033415385,0.000070211485,0.0020038614,0.0024387455,0.00024219256,0.00029947745,0.000008385606],"about_ca_topic_score_codex":0.00063426205,"about_ca_topic_score_gemma":0.0007308773,"teacher_disagreement_score":0.0020704523,"about_ca_system_score_codex":0.00011318429,"about_ca_system_score_gemma":0.00010086278,"threshold_uncertainty_score":0.0069263577},"labels":[],"label_agreement":null},{"id":"W4387033134","doi":"10.1172/jci169200","title":"The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Genentech; Sierra Oncology; Astellas Pharma; Eisai; Newcastle University; Prostate Cancer UK; National Institute for Health and Care Research; Wellcome Trust; JGW Patterson Foundation; Prostate Cancer Foundation; Movember Foundation; AstraZeneca; Pfizer; Amgen; Sanofi; Cancer Research UK; Vertex Pharmaceuticals","keywords":"Prostate cancer; Androgen receptor; RNA splicing; Signalling; Cancer research; Protein subunit; Alternative splicing; Function (biology); Prostate; Receptor; Medicine; Cancer; Cell biology; Chemistry; Biology; Computational biology; Internal medicine; Genetics; Gene isoform; Gene","score_opus":0.10274179390173648,"score_gpt":0.42657928142334484,"score_spread":0.32383748752160835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387033134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9792443,0.010691963,0.006073056,0.00036930814,0.00007830389,0.00004118918,0.00030972803,0.00014098774,0.0030511538],"genre_scores_gemma":[0.9956117,0.0018198683,0.0008135587,0.000025976016,0.000010443003,0.0000110609035,0.00017962568,0.000007660905,0.0015201191],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998752,0.000015546466,0.000008001307,0.00003725415,0.00003988201,0.000024038089],"domain_scores_gemma":[0.9999161,0.000010474607,0.00002918609,0.000007738657,0.00001111856,0.000025383155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010731845,0.00021512451,0.00014622115,0.0001856933,0.00015412716,0.00040076443,0.00016989297,0.00022190016,0.0014669555],"category_scores_gemma":[0.00017197216,0.00012467215,0.00015426244,0.00012970762,0.00026944574,0.00022314514,0.00015175494,0.00058859674,0.0005304506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022608522,0.000044189816,0.0013739152,0.00006398536,0.000005636888,0.00008497883,0.00002445183,0.00026294412,0.9913946,0.0005592323,0.000077395205,0.005882529],"study_design_scores_gemma":[0.000048665122,0.00057737855,0.030017763,0.000013869982,0.000020866752,0.001036844,0.00007761121,0.0020940294,0.95589876,0.00066161435,0.009540862,0.000011729971],"about_ca_topic_score_codex":0.00046047926,"about_ca_topic_score_gemma":0.0005345148,"teacher_disagreement_score":0.0014669555,"about_ca_system_score_codex":0.0004914494,"about_ca_system_score_gemma":0.00035743343,"threshold_uncertainty_score":0.004907489},"labels":[],"label_agreement":null},{"id":"W4387033187","doi":"10.1172/jci173495","title":"Glucagon-like peptide-1 receptor blockade impairs islet secretion and glucose metabolism in humans","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"National Institutes of Health; Ministero dell’Istruzione, dell’Università e della Ricerca; National Institute of Diabetes and Digestive and Kidney Diseases; Novo Nordisk; National Center for Advancing Translational Sciences; Dipartimenti di Eccellenza","keywords":"Internal medicine; Endocrinology; Islet; Glucagon; Proglucagon; Glucagon-like peptide-1; Insulin; Type 2 diabetes; Carbohydrate metabolism; Diabetes mellitus; Glucose clamp technique; Endogeny; Blockade; Biology; Blood sugar regulation; Pancreatic hormone; Receptor; Medicine; Insulin resistance","score_opus":0.0639552403383433,"score_gpt":0.3571097830082488,"score_spread":0.2931545426699055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387033187","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838058,0.009859471,0.000837824,0.00023527503,0.000100341895,0.000110431574,0.00031334048,0.00005415884,0.0046833022],"genre_scores_gemma":[0.99585587,0.001948182,0.00029635135,0.00047406694,0.00006658294,0.0000846862,0.00034918322,0.000009819841,0.00091514015],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997981,0.00005964682,0.000012053144,0.00005878428,0.0000327392,0.00003863526],"domain_scores_gemma":[0.99986565,0.000024443707,0.000038272963,0.000022752381,0.000008601408,0.00004032212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046673705,0.00029962976,0.000609838,0.0001582899,0.00020560455,0.00041220846,0.00012897058,0.00029972492,0.0018346859],"category_scores_gemma":[0.00035941388,0.00012390607,0.00024711597,0.00020922255,0.00025931423,0.00019453192,0.00017422675,0.00038871312,0.00029065507],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10701721,0.009667848,0.38839522,0.0012568788,0.0016365815,0.0116223395,0.00055441476,0.0012199772,0.16014636,0.0014964152,0.011588682,0.30539808],"study_design_scores_gemma":[0.0061571766,0.08028164,0.84599245,0.00033370478,0.0011538629,0.016755657,0.00035946426,0.0015965855,0.015835425,0.001698014,0.029758757,0.000077370154],"about_ca_topic_score_codex":0.00030711846,"about_ca_topic_score_gemma":0.00027064374,"teacher_disagreement_score":0.0018346859,"about_ca_system_score_codex":0.00022780013,"about_ca_system_score_gemma":0.00018997355,"threshold_uncertainty_score":0.006137669},"labels":[],"label_agreement":null},{"id":"W4387653137","doi":"10.1172/jci174319","title":"Chemical carcinogens: implications for cancer treatment","year":2023,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research; Cancer Research Institute","keywords":"Carcinogen; Immunogenicity; Cancer; Tumor microenvironment; Cancer research; Immune system; Reprogramming; Immunotherapy; Cancer immunotherapy; Lung cancer; Immunology; Carcinogenesis; Biology; Medicine; Cell; Oncology; Genetics","score_opus":0.18491450813477303,"score_gpt":0.41939149949033266,"score_spread":0.23447699135555963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387653137","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010990201,0.05327374,0.0007128024,0.89856493,0.03531382,0.000031242667,0.00005497753,0.00008655566,0.010862845],"genre_scores_gemma":[0.023300061,0.096676655,0.002337934,0.6177391,0.22935098,0.000117146454,0.00012043613,0.000041496052,0.030316172],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992768,0.00019545118,0.00007282945,0.0001001895,0.00028478308,0.000069992115],"domain_scores_gemma":[0.9981865,0.000814214,0.000121795536,0.00014157192,0.00042010267,0.00031575788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012095384,0.00058113155,0.0006684771,0.0004706025,0.0009858692,0.0015517849,0.00076678296,0.00942607,0.0090690395],"category_scores_gemma":[0.004013027,0.00024237725,0.0006649408,0.00026597403,0.0016310418,0.0020352954,0.0006684526,0.010359305,0.0063928114],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013448033,0.00023349986,0.0010152913,0.0004811335,0.000019805775,0.003935158,0.000058932368,0.000224527,0.0025885028,0.013867651,0.80066514,0.17677599],"study_design_scores_gemma":[0.00006127226,0.00013734437,0.0007117424,0.00029499308,0.000016247706,0.005290312,0.000099419514,0.00031472725,0.00046438992,0.0140964575,0.9784934,0.000019653804],"about_ca_topic_score_codex":0.0005324307,"about_ca_topic_score_gemma":0.0014384922,"teacher_disagreement_score":0.00942607,"about_ca_system_score_codex":0.0019510912,"about_ca_system_score_gemma":0.0012532574,"threshold_uncertainty_score":0.030338883},"labels":[],"label_agreement":null},{"id":"W4388041029","doi":"10.1172/jci166884","title":"Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Chemical Laboratory; National Cancer Institute; National Institutes of Health; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine; John S. Dunn Gulf Coast Consortium for Chemical Genomics; National Institute of Environmental Health Sciences; Leona M. and Harry B. Helmsley Charitable Trust; Cancer Prevention and Research Institute of Texas","keywords":"Organoid; Enteroendocrine cell; Biology; Pathogenesis; Stem cell; Cell growth; Etiology; Disease; Bioinformatics; Cancer research; Medicine; Pathology; Cell biology; Endocrine system; Endocrinology; Hormone; Immunology; Genetics","score_opus":0.07566925136771158,"score_gpt":0.35942408292581357,"score_spread":0.283754831558102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388041029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917464,0.0020654101,0.001876277,0.00012877354,0.00004336959,0.000051478157,0.0011377938,0.00006748638,0.0028829263],"genre_scores_gemma":[0.99458826,0.000676613,0.0013732916,0.0000661061,0.0000062784106,0.000036308476,0.001741099,0.000014398713,0.0014975406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986374,0.000020927999,0.000017020802,0.00003240721,0.00004131094,0.000024534464],"domain_scores_gemma":[0.9997757,0.00007785791,0.000017030035,0.000044566194,0.000023288958,0.000061637285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013072416,0.00021592368,0.00023123667,0.00043601278,0.00024350526,0.00031407393,0.00014278105,0.0003807329,0.0023973065],"category_scores_gemma":[0.00023001868,0.00011749986,0.00027705057,0.00033281997,0.00025793238,0.00014088175,0.00026970793,0.000573098,0.0005311308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008030266,0.000046363497,0.0042638676,0.00011080778,0.00002379255,0.0029729162,0.0003439837,0.00020308107,0.9870123,0.00018586282,0.0002565817,0.0037773978],"study_design_scores_gemma":[0.00021718908,0.002552611,0.16013353,0.00006110142,0.00014502836,0.022383722,0.0021719376,0.0030243532,0.78310394,0.0003722541,0.02576965,0.000064658176],"about_ca_topic_score_codex":0.0024724891,"about_ca_topic_score_gemma":0.0032216555,"teacher_disagreement_score":0.0024724891,"about_ca_system_score_codex":0.00023332286,"about_ca_system_score_gemma":0.00017083091,"threshold_uncertainty_score":0.008019745},"labels":[],"label_agreement":null},{"id":"W4388042143","doi":"10.1172/jci157165","title":"Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"Perelman School of Medicine, University of Pennsylvania; National Institutes of Health; OeAD-GmbH; Medizinische Universität Graz; National Institute of Diabetes and Digestive and Kidney Diseases; Karl-Franzens-Universität Graz; Deutsche Forschungsgemeinschaft; University of Pennsylvania","keywords":"Mineralocorticoid receptor; Endocrinology; Epithelial sodium channel; Internal medicine; Mineralocorticoid; Kidney; Albuminuria; Aldosterone; Kidney disease; Distal convoluted tubule; Biology; Medicine; Chemistry; Reabsorption; Sodium","score_opus":0.10269165817528444,"score_gpt":0.35746890793722147,"score_spread":0.25477724976193705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388042143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96034074,0.00435685,0.030872064,0.00015394394,0.000044268338,0.000050798204,0.0024781518,0.00015314706,0.0015501225],"genre_scores_gemma":[0.9823072,0.0022630775,0.011429081,0.00014374635,0.0000337509,0.000071828195,0.0016434027,0.00003608368,0.0020718365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998442,0.000014643821,0.000008004426,0.000059149937,0.000049761104,0.000024340321],"domain_scores_gemma":[0.9998903,0.000028472716,0.000025385067,0.000014875113,0.000024172938,0.000016705793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001874863,0.00015575852,0.00038815397,0.00026235037,0.00013880545,0.00037329158,0.00014906275,0.00021183383,0.0006414662],"category_scores_gemma":[0.00015984867,0.00012626479,0.00025099216,0.00021777353,0.00016403195,0.00022490046,0.00016918847,0.00028069573,0.00022938116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003309542,0.000005707808,0.0008776036,0.000023294886,0.0000063430894,0.000011573119,0.000014004679,0.00007614941,0.9971752,0.00004981101,0.000021640311,0.001705614],"study_design_scores_gemma":[0.000013255074,0.00029003964,0.119724825,0.000008824228,0.000062824016,0.00023786878,0.0001724208,0.0067971987,0.8677863,0.0003842485,0.0045039393,0.000018253386],"about_ca_topic_score_codex":0.00047683032,"about_ca_topic_score_gemma":0.0013666494,"teacher_disagreement_score":0.0006414662,"about_ca_system_score_codex":0.00014829577,"about_ca_system_score_gemma":0.00014859116,"threshold_uncertainty_score":0.0021458864},"labels":[],"label_agreement":null},{"id":"W4388048581","doi":"10.1172/jci166740","title":"Breast cancer immunopeptidomes contain numerous shared tumor antigens","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Cancer Society","keywords":"Breast cancer; Immunogenicity; Triple-negative breast cancer; Cancer immunotherapy; Antigen; Immunotherapy; Cancer research; Cancer; Immune checkpoint; Blockade; Biology; Oncology; Medicine; Immunology; Internal medicine; Receptor","score_opus":0.05626000602586655,"score_gpt":0.36244685979737995,"score_spread":0.3061868537715134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388048581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879532,0.004976754,0.0026753824,0.00007982525,0.000024805851,0.0000266343,0.0016193313,0.000051809653,0.0025921597],"genre_scores_gemma":[0.9868383,0.0022456655,0.0042828047,0.00012049357,0.000022865454,0.000044150926,0.00332069,0.00002941484,0.0030957588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984384,0.000019771103,0.000012922913,0.000047032623,0.00004826488,0.00002824654],"domain_scores_gemma":[0.99990416,0.000016412989,0.000038345574,0.000011567203,0.000012288658,0.000017182188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009600606,0.00033973696,0.0002464407,0.00047302913,0.00022065453,0.00030462665,0.00013239462,0.00019516023,0.0026483424],"category_scores_gemma":[0.0001699155,0.000106743544,0.0002001325,0.00050323695,0.00010351134,0.00016262161,0.00027927855,0.00025066474,0.00075209106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015402558,0.0000178193,0.0062348307,0.000085479485,0.00003060841,0.0001965174,0.000022564795,0.000053198302,0.9834699,0.00009566202,0.00012832064,0.009511008],"study_design_scores_gemma":[0.000037744096,0.0006036087,0.34394157,0.00003915049,0.00014704534,0.009172992,0.00017576916,0.0011890806,0.61036706,0.00042733847,0.033881422,0.000017165989],"about_ca_topic_score_codex":0.00032177658,"about_ca_topic_score_gemma":0.0004808206,"teacher_disagreement_score":0.0026483424,"about_ca_system_score_codex":0.00021635191,"about_ca_system_score_gemma":0.000116932046,"threshold_uncertainty_score":0.008859634},"labels":[],"label_agreement":null},{"id":"W4388654287","doi":"10.1172/jci171235","title":"Spliceosome malfunction causes neurodevelopmental disorders with overlapping features","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Centre Hospitalier Universitaire Sainte-Justine; London Health Sciences Centre; McMaster University; McMaster Children's Hospital; SickKids Foundation; University of Toronto; University Health Network; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; NIH Office of the Director; National Human Genome Research Institute; National Institutes of Health; Novo Nordisk Fonden; Eagles Autism Foundation; Common Fund; Wellcome Trust; University of Rochester; Pennsylvania Department of Health","keywords":"Medicine; Spliceosome; Genetics; Bioinformatics; Biology; RNA splicing; RNA","score_opus":0.04362714930798609,"score_gpt":0.34867146070193994,"score_spread":0.3050443113939538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388654287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996191,0.0017242996,0.0009964659,0.00004219449,0.000008030734,0.000013397588,0.0002490856,0.00003914421,0.0007362356],"genre_scores_gemma":[0.99844545,0.00064302154,0.00045192157,0.000024063906,0.000007695176,0.000005266263,0.00024438676,0.0000061499136,0.00017198297],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99978644,0.00003062441,0.00003998647,0.0000797353,0.000037370544,0.000025744039],"domain_scores_gemma":[0.9998165,0.000032668162,0.00009455946,0.00001518857,0.000013443859,0.000027699814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017664472,0.0007674646,0.0002976921,0.0007551926,0.00024526447,0.00020573947,0.00018256775,0.00030648962,0.0011174121],"category_scores_gemma":[0.00038629,0.000115416835,0.00018541128,0.0005657643,0.00046619284,0.000122043835,0.00038063002,0.00017613714,0.00018830055],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001677804,0.00018300358,0.34209397,0.0002910658,0.0002999743,0.047533568,0.0003326386,0.0004302999,0.5566889,0.0011322176,0.00075727724,0.048579253],"study_design_scores_gemma":[0.000056057746,0.0007124008,0.7340598,0.000059524704,0.0003556683,0.15390232,0.00034716414,0.0013281174,0.10426057,0.00087458064,0.004023773,0.000020076764],"about_ca_topic_score_codex":0.00052238186,"about_ca_topic_score_gemma":0.0005197381,"teacher_disagreement_score":0.0011174121,"about_ca_system_score_codex":0.00018392586,"about_ca_system_score_gemma":0.00016010249,"threshold_uncertainty_score":0.0037381053},"labels":[],"label_agreement":null},{"id":"W4388859922","doi":"10.1172/jci173299","title":"AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"National Natural Science Foundation of China; Shanghai Association for Science and Technology","keywords":"Alternative splicing; RNA splicing; Exon; Biology; RNA-binding protein; Cancer cell; Gene isoform; Frameshift mutation; Cell biology; Cancer research; RNA; Chemistry; Cancer; Gene; Biochemistry; Genetics","score_opus":0.09944095742426691,"score_gpt":0.38665435179305485,"score_spread":0.28721339436878796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388859922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99601644,0.00078086933,0.0021708943,0.000058044832,0.00001824244,0.000018323308,0.00014671785,0.000025102523,0.0007653998],"genre_scores_gemma":[0.9972249,0.00036814826,0.0011309324,0.00004667359,0.0000051168186,0.000015651103,0.00029655648,0.000008971171,0.00090300984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999124,0.000016174172,0.000011122994,0.000021660697,0.000020170723,0.00001849858],"domain_scores_gemma":[0.9999373,0.000015754571,0.0000167684,0.0000096618,0.000006563137,0.000013948275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011868245,0.00018551898,0.00013457455,0.000062566956,0.00008559101,0.00016621937,0.0000809292,0.00013928991,0.0006833167],"category_scores_gemma":[0.000107601576,0.00007401269,0.00016711728,0.000061175,0.00013994052,0.000101610356,0.00015135003,0.00031323545,0.00014330565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070111375,0.00000825629,0.000121657366,0.000011544632,0.0000025531149,0.000033637843,0.000004957108,0.000027572169,0.99912435,0.00004236974,0.000013501006,0.0005395273],"study_design_scores_gemma":[0.000008188393,0.000111869515,0.002635252,0.0000013894132,0.0000039923334,0.0002133448,0.000010779918,0.00041080988,0.99570495,0.000033745102,0.0008641384,0.0000015536787],"about_ca_topic_score_codex":0.0001865951,"about_ca_topic_score_gemma":0.00025566618,"teacher_disagreement_score":0.0006833167,"about_ca_system_score_codex":0.00013761448,"about_ca_system_score_gemma":0.00010029518,"threshold_uncertainty_score":0.0022858977},"labels":[],"label_agreement":null},{"id":"W4389166145","doi":"10.1172/jci175288","title":"Human brown adipose tissue is not enough to combat cardiometabolic diseases","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke","funders":"Canadian Institutes of Health Research; Université de Sherbrooke; GlaxoSmithKline","keywords":"Adipose tissue; Brown adipose tissue; Medicine; Bioinformatics; Physiology; Biology; Endocrinology","score_opus":0.1254477990649705,"score_gpt":0.4312979823160772,"score_spread":0.3058501832511067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389166145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5127309,0.32178724,0.009464029,0.07834528,0.017436255,0.00025647608,0.0010788678,0.00047246212,0.05842853],"genre_scores_gemma":[0.9153369,0.044415493,0.005849627,0.017515892,0.0027752796,0.0001743144,0.0005922059,0.00008596783,0.013254281],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9992661,0.00029924203,0.00006557572,0.000069487905,0.00020439217,0.000095308795],"domain_scores_gemma":[0.9993661,0.0001727018,0.00008344641,0.0001261292,0.00012155713,0.00013015345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015269723,0.0004368573,0.00093448564,0.00024306664,0.0003014475,0.0017083407,0.00023809975,0.00063531206,0.0053293156],"category_scores_gemma":[0.0014665889,0.00020343337,0.00024032735,0.00024000564,0.0011738697,0.0007994609,0.0006884857,0.0016562839,0.0013543062],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010711372,0.0013725407,0.0155744385,0.002079386,0.000985875,0.0013954001,0.00036524565,0.0008168294,0.5355599,0.0138070015,0.033706937,0.38362512],"study_design_scores_gemma":[0.0021028162,0.016564107,0.048640404,0.0023180116,0.0010116643,0.008395526,0.0023667212,0.001106229,0.2478453,0.023825385,0.6457001,0.00012386253],"about_ca_topic_score_codex":0.000259519,"about_ca_topic_score_gemma":0.0004178936,"teacher_disagreement_score":0.0053293156,"about_ca_system_score_codex":0.0003138222,"about_ca_system_score_gemma":0.0007496233,"threshold_uncertainty_score":0.017828345},"labels":[],"label_agreement":null},{"id":"W4389166181","doi":"10.1172/jci174952","title":"The gift of preexisting immunity for developing an alternative vaccine strategy","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; National Institutes of Health; Fonds de Recherche du Québec - Santé; Bill and Melinda Gates Foundation","keywords":"Immunity; Medicine; Vaccination; Immunology; Pandemic; Adjuvant; Virology; Disease; Influenza vaccine; Immune system; Infectious disease (medical specialty); Coronavirus disease 2019 (COVID-19); Internal medicine","score_opus":0.5310517054774201,"score_gpt":0.5648715451551933,"score_spread":0.033819839677773245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389166181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35185707,0.1660988,0.3197391,0.060229406,0.016079884,0.0014671969,0.0008264635,0.0016423296,0.08205975],"genre_scores_gemma":[0.77672887,0.080870755,0.10197588,0.01495115,0.0021744783,0.0006802947,0.0006145687,0.00017065209,0.021833377],"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99973434,0.00007098553,0.000020275724,0.00004098622,0.00007073954,0.00006258707],"domain_scores_gemma":[0.9997532,0.00007090554,0.00003545079,0.000048721933,0.000046571466,0.00004523083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082168414,0.00047298806,0.0004747244,0.00023823896,0.00026752744,0.0011432889,0.00051612145,0.0011839567,0.0034245243],"category_scores_gemma":[0.0006710162,0.00024466866,0.00045603173,0.00011209227,0.0006786676,0.002035896,0.0006380107,0.002756343,0.0012643611],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039820033,0.0007366391,0.00074137974,0.0011973367,0.000086107626,0.0004090736,0.00015123864,0.0010706936,0.7864228,0.04585912,0.0093063265,0.15362109],"study_design_scores_gemma":[0.0003583944,0.0058650915,0.0017731957,0.0003921834,0.00023882912,0.0016216747,0.00023227776,0.0057033105,0.5353776,0.020961154,0.42740154,0.000074635886],"about_ca_topic_score_codex":0.00015248556,"about_ca_topic_score_gemma":0.00036403333,"teacher_disagreement_score":0.0034245243,"about_ca_system_score_codex":0.00043787653,"about_ca_system_score_gemma":0.0005011031,"threshold_uncertainty_score":0.011456192},"labels":[],"label_agreement":null},{"id":"W4389802235","doi":"10.1172/jci163470","title":"Foxp3-mediated blockage of ryanodine receptor 2 underlies contact-based suppression by regulatory T cells","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Jiangsu Science and Technology Department; Tsinghua University; National Natural Science Foundation of China; University of Calgary","keywords":"FOXP3; Ryanodine receptor; Immunology; Autoimmunity; Immune system; Cell biology; Biology; Effector; Ryanodine receptor 2","score_opus":0.041345501750492016,"score_gpt":0.3040037429278679,"score_spread":0.2626582411773759,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389802235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99244577,0.0021476264,0.0034693645,0.00015082,0.00004668582,0.000040431274,0.00008675487,0.00016081675,0.0014516761],"genre_scores_gemma":[0.99862134,0.00023705549,0.00045970996,0.000034424476,0.000024567484,0.000014144102,0.000041732506,0.00001040336,0.0005566389],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997359,0.000045551933,0.00002215331,0.00005598972,0.000048659607,0.00009170609],"domain_scores_gemma":[0.9998431,0.00002719497,0.000052119445,0.00002032965,0.00001067873,0.00004652278],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003192879,0.00033541198,0.0003691018,0.00014296634,0.00015955826,0.00024653188,0.00026592004,0.00036414218,0.0013756952],"category_scores_gemma":[0.00020677745,0.00011958968,0.0002959887,0.00005949976,0.00046191132,0.0002139771,0.00023272121,0.0008492934,0.0003336708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026455912,0.000045277568,0.00032895224,0.000038271395,0.0000039870124,0.00018060698,0.000016163762,0.00004625313,0.997244,0.00015866185,0.000045102894,0.0016282221],"study_design_scores_gemma":[0.00023368679,0.0016647674,0.016828762,0.000015503478,0.00004339065,0.002281745,0.000067456516,0.0026107985,0.9724975,0.00064661336,0.0031004723,0.000009352357],"about_ca_topic_score_codex":0.0001666566,"about_ca_topic_score_gemma":0.00030546394,"teacher_disagreement_score":0.0013756952,"about_ca_system_score_codex":0.00019996922,"about_ca_system_score_gemma":0.00019958768,"threshold_uncertainty_score":0.004602194},"labels":[],"label_agreement":null},{"id":"W4389947337","doi":"10.1172/jci170594","title":"Bik promotes proteasomal degradation to control low-grade inflammation","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Environmental Health Sciences; Ohio State University; University of North Carolina at Chapel Hill; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Brigham and Women's Hospital; Cystic Fibrosis Foundation","keywords":"Inflammation; Immunology; Medicine","score_opus":0.04320515226955572,"score_gpt":0.33869690389015367,"score_spread":0.29549175162059793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389947337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96482354,0.01764513,0.012256852,0.000659566,0.0001576097,0.00009628875,0.0004318312,0.00038864493,0.0035406526],"genre_scores_gemma":[0.9908173,0.0028507353,0.0035039205,0.00008143954,0.000021142116,0.0000484968,0.00022663207,0.000021421507,0.0024288604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998553,0.000025860605,0.000013679901,0.00003077379,0.00003107804,0.000043206426],"domain_scores_gemma":[0.99987936,0.000007882033,0.000042811327,0.000011357403,0.0000134353995,0.000045072513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021703704,0.0003665043,0.0002554688,0.00028210747,0.00020006362,0.00043517048,0.00025921187,0.00024881892,0.0012094693],"category_scores_gemma":[0.00015027121,0.00012741597,0.00017895168,0.00014788796,0.00021975925,0.00024675648,0.00033899688,0.0006560558,0.00045272676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031375638,0.000045167064,0.0005387193,0.000082917824,0.000009994547,0.000059964656,0.0000111314175,0.000056799498,0.9956672,0.00030055875,0.000113933325,0.0027999892],"study_design_scores_gemma":[0.00012656953,0.0005963787,0.018488705,0.000029130208,0.00004856153,0.0009274006,0.00004549434,0.0019981607,0.9669366,0.00037505856,0.010411823,0.000016170383],"about_ca_topic_score_codex":0.00023842529,"about_ca_topic_score_gemma":0.00048331183,"teacher_disagreement_score":0.0012094693,"about_ca_system_score_codex":0.0004033508,"about_ca_system_score_gemma":0.00025514772,"threshold_uncertainty_score":0.0040460825},"labels":[],"label_agreement":null},{"id":"W4390120447","doi":"10.1172/jci174508","title":"Mechanosensitive channels TMEM63A and TMEM63B mediate lung inflation–induced surfactant secretion","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"Natural Science Foundation of Sichuan Province; National Natural Science Foundation of China","keywords":"Lamellar granule; Mechanosensitive channels; Pulmonary surfactant; Cell biology; Secretion; Lung; Alveolar cells; Chemistry; Biology; Endocrinology; Internal medicine; Medicine; Biochemistry; Receptor; Ion channel","score_opus":0.16207765356327236,"score_gpt":0.4745671265137018,"score_spread":0.31248947295042945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390120447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855794,0.0051480234,0.005929462,0.00039610578,0.000114277944,0.00004418418,0.00024839776,0.00012555635,0.002414553],"genre_scores_gemma":[0.9955362,0.0013671992,0.0012423273,0.000095403804,0.000027210808,0.00002974757,0.00011977575,0.00000900995,0.0015731738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999884,0.00001672772,0.000009879667,0.000022142842,0.000027262588,0.000039893544],"domain_scores_gemma":[0.99992406,0.0000070325354,0.000020058644,0.0000066147268,0.000013593861,0.000028657918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015141182,0.00022266398,0.00023421532,0.00013849171,0.0002364395,0.00034049505,0.00021720513,0.00039572455,0.0009868061],"category_scores_gemma":[0.0001617744,0.00007363942,0.00019904642,0.00007659859,0.00026986224,0.00039547696,0.00039726443,0.0005823844,0.00028211233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012003098,0.000018480221,0.0005258862,0.00003663015,0.0000027485978,0.00016464535,0.000022019743,0.000027955388,0.99714965,0.00023001934,0.00007606762,0.001625846],"study_design_scores_gemma":[0.000055211138,0.00043204598,0.037876517,0.000036095335,0.000019962614,0.0018184908,0.0002468565,0.0023631286,0.9483428,0.00064965093,0.008142401,0.00001687753],"about_ca_topic_score_codex":0.00028754957,"about_ca_topic_score_gemma":0.00023405993,"teacher_disagreement_score":0.0009868061,"about_ca_system_score_codex":0.00021603591,"about_ca_system_score_gemma":0.0001576541,"threshold_uncertainty_score":0.0033012033},"labels":[],"label_agreement":null},{"id":"W4390875529","doi":"10.1172/jci169241","title":"FGFR inhibition augments anti–PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Gillings School of Public Health; York University; National Cancer Institute; University of North Carolina at Chapel Hill; National Institutes of Health; Uehara Memorial Foundation","keywords":"Fibroblast growth factor receptor; Cancer research; Fibroblast growth factor; In vivo; Immunosuppression; Biology; Receptor; Immunology","score_opus":0.061160462635822935,"score_gpt":0.41870732933391624,"score_spread":0.3575468666980933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390875529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977926,0.00055597856,0.0004357754,0.00006966365,0.000028614724,0.00002382435,0.00023130221,0.000055762546,0.0008064926],"genre_scores_gemma":[0.9977943,0.00035136743,0.0006276355,0.0000340813,0.000010335553,0.00002465842,0.00024275907,0.000008416892,0.00090635655],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999813,0.000034534158,0.000016677599,0.00002096849,0.000036553345,0.000078183824],"domain_scores_gemma":[0.99990356,0.000014715082,0.000028298082,0.000011819841,0.000007851127,0.00003380196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001759389,0.0003532779,0.00029505134,0.0002792642,0.00014383695,0.00023968161,0.00023548961,0.00029033795,0.00091854495],"category_scores_gemma":[0.000103326136,0.00011632373,0.00028059058,0.00013780672,0.00018604047,0.00019316729,0.00011916417,0.00089054235,0.00020698593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008644128,0.0005596851,0.00031830146,0.000057796104,0.000013211422,0.00005971326,0.000023931601,0.00045028632,0.9923463,0.00011285127,0.0001864644,0.0050070668],"study_design_scores_gemma":[0.0001618431,0.006648403,0.0046601347,0.000011001122,0.000040930965,0.00032887742,0.000034649413,0.0024291647,0.98322195,0.000053345106,0.0024004485,0.000009221502],"about_ca_topic_score_codex":0.0007527851,"about_ca_topic_score_gemma":0.0017240233,"teacher_disagreement_score":0.00091854495,"about_ca_system_score_codex":0.00025664087,"about_ca_system_score_gemma":0.00027168848,"threshold_uncertainty_score":0.0030727983},"labels":[],"label_agreement":null},{"id":"W4391231869","doi":"10.1172/jci172760","title":"p40 homodimers bridge ischemic tissue inflammation and heterologous alloimmunity in mice via IL-15 transpresentation","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Alloimmunity; Effector; CD8; Memory T cell; Heterologous; Biology; T cell; Cytotoxic T cell; Cell biology; Inflammation; Immunology; Immune system; In vitro","score_opus":0.0467201214674135,"score_gpt":0.3443934038866525,"score_spread":0.297673282419239,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391231869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99670535,0.00058594026,0.0013712115,0.000120568555,0.000033826753,0.0000479109,0.00019201956,0.00010820937,0.0008349481],"genre_scores_gemma":[0.9942327,0.0004867117,0.0019520794,0.00009602671,0.00003294886,0.00011453842,0.00033214365,0.00003486724,0.0027179641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996594,0.000070654285,0.000032123957,0.000066915694,0.000058594793,0.000112168236],"domain_scores_gemma":[0.9998006,0.000022214217,0.00006559447,0.00002656658,0.000008853109,0.00007619708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003419865,0.0005824943,0.00034625476,0.00062853534,0.00020370007,0.00040452875,0.00025021515,0.00054578466,0.0014537527],"category_scores_gemma":[0.0001245152,0.00028495528,0.00029359697,0.00017030089,0.00050467905,0.00042696687,0.00027227402,0.001626192,0.00044229077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051587884,0.00032638563,0.000114167044,0.000027059647,0.0000036211243,0.00003952588,0.000030907126,0.00007430827,0.99745566,0.00017957606,0.000047792757,0.0011850777],"study_design_scores_gemma":[0.00018791178,0.0035103583,0.0038230193,0.000018362403,0.000020470485,0.000297882,0.00006585281,0.0014427648,0.9886829,0.0001817474,0.0017612043,0.000007442439],"about_ca_topic_score_codex":0.00023568392,"about_ca_topic_score_gemma":0.00036289042,"teacher_disagreement_score":0.0014537527,"about_ca_system_score_codex":0.00030197907,"about_ca_system_score_gemma":0.00023574484,"threshold_uncertainty_score":0.004863322},"labels":[],"label_agreement":null},{"id":"W4391340227","doi":"10.1172/jci173782","title":"mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Novo Nordisk Foundation Center for Basic Metabolic Research; Novo Nordisk Fonden; Novo Nordisk; University of Pennsylvania","keywords":"Postprandial; Glycogen; Liver metabolism; mTORC1; Glycogen synthase; Chemistry; Endocrinology; Biochemistry; Gluconeogenesis; Internal medicine; Biology; Metabolism; Medicine; Insulin; Phosphorylation","score_opus":0.028430970165913144,"score_gpt":0.32095518718512117,"score_spread":0.29252421701920805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391340227","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849577,0.001589011,0.006514904,0.00036183887,0.00006593473,0.000059117036,0.0023708008,0.0003888949,0.0036917948],"genre_scores_gemma":[0.9851799,0.0012173863,0.0050856504,0.00016877608,0.000015546622,0.00015822207,0.0016587242,0.00023418812,0.0062816795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997155,0.000048571546,0.00002901081,0.00007471387,0.00006706051,0.000065136264],"domain_scores_gemma":[0.9998288,0.0000137202105,0.000060481358,0.000019672909,0.000013348209,0.000063996595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028969508,0.00038256933,0.0002943526,0.00064602104,0.0002965686,0.00040644873,0.00036781075,0.00030977977,0.0019050662],"category_scores_gemma":[0.00013198546,0.00034808533,0.0003230137,0.00027177163,0.0005285678,0.00017097138,0.00036453793,0.00078794296,0.00091042725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031436948,0.00004015893,0.00023802949,0.000028056264,0.000004672429,0.000055773933,0.00002113305,0.00016294768,0.9972029,0.00041368394,0.00012482224,0.0013934379],"study_design_scores_gemma":[0.00009806839,0.00034257513,0.007457705,0.000026219983,0.000026306292,0.00026026546,0.000052166248,0.0020591344,0.98447543,0.00024902177,0.0049413526,0.000011708991],"about_ca_topic_score_codex":0.0013817825,"about_ca_topic_score_gemma":0.0026172418,"teacher_disagreement_score":0.0019050662,"about_ca_system_score_codex":0.0007123217,"about_ca_system_score_gemma":0.00060268515,"threshold_uncertainty_score":0.006373048},"labels":[],"label_agreement":null},{"id":"W4391430175","doi":"10.1172/jci176454","title":"HER2 heterogeneity and treatment response–associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Genentech; Astellas Pharma; Eisai; Knight Cancer Institute, Oregon Health and Science University; G1 Therapeutics; MacroGenics; Puma Biotechnology; Incyte; National Cancer Institute; Natera; Genomic Health; Daiichi Sankyo Europe; Sanofi; Oregon Health and Science University; Gilead Sciences; University of Texas Southwestern Medical Center; Amgen; Pfizer; Susan G. Komen for the Cure; AstraZeneca; Eli Lilly and Company","keywords":"Breast cancer; Trastuzumab; Medicine; Pertuzumab; Lapatinib; Oncology; Internal medicine; KRAS; Neoadjuvant therapy; ErbB; Cancer research; Cancer; Colorectal cancer","score_opus":0.25934820909865275,"score_gpt":0.5403783004386817,"score_spread":0.281030091340029,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391430175","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915029,0.00096050854,0.00031973148,0.00042277513,0.000042263826,0.0010235121,0.0029757663,0.000049694914,0.0027027756],"genre_scores_gemma":[0.99045277,0.00022111168,0.000543353,0.0005233995,0.000059753955,0.0016193817,0.00484488,0.000022773607,0.001712582],"study_design_codex":"randomized_trial","study_design_gemma":"observational","domain_scores_codex":[0.9990545,0.00049546495,0.000053843,0.00012967546,0.00011227314,0.0001542127],"domain_scores_gemma":[0.9994381,0.0001376197,0.00016359943,0.000050061833,0.000045731864,0.00016492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026062885,0.0005544574,0.001166079,0.00034750364,0.00038825924,0.0007145175,0.00037349906,0.0008721731,0.003401125],"category_scores_gemma":[0.0013205569,0.00021528188,0.00047060364,0.00055022206,0.000446675,0.0006065394,0.0003683722,0.0011247381,0.000549804],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.7685505,0.009054597,0.09110963,0.00057275075,0.0019332311,0.00045519407,0.0002282747,0.0036699546,0.04309681,0.000596424,0.01039567,0.07033695],"study_design_scores_gemma":[0.27401087,0.19862853,0.48586595,0.00009437916,0.002406679,0.0011192192,0.00027843713,0.005907751,0.011126013,0.0023850983,0.01804962,0.00012744644],"about_ca_topic_score_codex":0.00058082974,"about_ca_topic_score_gemma":0.0022406091,"teacher_disagreement_score":0.003401125,"about_ca_system_score_codex":0.00078950933,"about_ca_system_score_gemma":0.0009821553,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W4391805863","doi":"10.1172/jci174824","title":"A metabolic signature for NADSYN1-dependent congenital NAD deficiency disorder","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; Mount Sinai Hospital","funders":"National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health; Medical Research Council; NSW Ministry of Health; National Institute for Health and Care Research; National Health and Medical Research Council; Broad Institute","keywords":"NAD+ kinase; Nicotinamide adenine dinucleotide; Nicotinamide; Metabolome; Nicotinamide mononucleotide; Biology; Newborn screening; Phenotype; Biochemistry; Genetics; Enzyme; Gene; Metabolite","score_opus":0.04280033503312107,"score_gpt":0.36905041256544086,"score_spread":0.32625007753231977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391805863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98973924,0.0012197793,0.0044890847,0.0001614909,0.00001838367,0.000038813225,0.0018080932,0.00021128834,0.0023138337],"genre_scores_gemma":[0.9910913,0.0010603399,0.0046495474,0.00013521801,0.000005616038,0.00002507133,0.0014255776,0.000046141075,0.0015610293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999386,0.000006763557,0.000005470832,0.000024770117,0.000017928214,0.000006546224],"domain_scores_gemma":[0.99993634,0.000010216257,0.000025794447,0.0000050260596,0.0000068797226,0.000015751582],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055768814,0.00031757177,0.0001387213,0.00037961046,0.00013219933,0.0001564204,0.00011600338,0.00022820992,0.0014078731],"category_scores_gemma":[0.00012047191,0.00009125551,0.00012861787,0.00026755908,0.0001600999,0.000067961235,0.00016647458,0.00025507377,0.0002464569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004241123,0.000020422181,0.013733504,0.000066467466,0.000017729992,0.0034356345,0.000060363225,0.0001651732,0.97237676,0.0002360005,0.0003108467,0.009152994],"study_design_scores_gemma":[0.000042614014,0.000759581,0.27100044,0.00005196053,0.00014634793,0.059967242,0.00022312331,0.0030434947,0.64876395,0.0009259474,0.015041769,0.000033520482],"about_ca_topic_score_codex":0.0006369587,"about_ca_topic_score_gemma":0.0011135527,"teacher_disagreement_score":0.0014078731,"about_ca_system_score_codex":0.00015703417,"about_ca_system_score_gemma":0.00013749838,"threshold_uncertainty_score":0.00470978},"labels":[],"label_agreement":null},{"id":"W4392032909","doi":"10.1172/jci170559","title":"Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Microsemi (Canada)","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Institutes of Health; University of Texas Southwestern Medical Center; Cancer Prevention and Research Institute of Texas; U.S. Department of Defense","keywords":"TFEB; Biology; TFE3; Carcinogenesis; Cancer research; mTORC1; Cell biology; Cancer; Genetics; Autophagy; Signal transduction; Gene; PI3K/AKT/mTOR pathway; Gene expression; Apoptosis","score_opus":0.11307634480716948,"score_gpt":0.3587772021913969,"score_spread":0.24570085738422742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392032909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95585483,0.0016093877,0.028645623,0.00034276515,0.00008660383,0.00021156363,0.00759181,0.000666,0.00499129],"genre_scores_gemma":[0.96794343,0.0019396769,0.0134922005,0.00015540657,0.000018906341,0.0003347693,0.006790166,0.00017908198,0.009146334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953175,0.000048921564,0.00004173508,0.00017166005,0.000115722876,0.000090290334],"domain_scores_gemma":[0.9998497,0.000018605855,0.000046504858,0.000030158952,0.000015275622,0.000039827853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029962318,0.000553412,0.00034493327,0.0017494506,0.0003538494,0.00047662196,0.00037826627,0.00061859493,0.0046420335],"category_scores_gemma":[0.00014204897,0.00027746585,0.0007441321,0.0006133096,0.00047412066,0.00037548455,0.0004008588,0.0011440428,0.0008506666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002059764,0.000072760704,0.0004418177,0.000034111657,0.0000142721865,0.00022939767,0.000034304194,0.00019997719,0.99595237,0.0007543182,0.000100383055,0.0019603272],"study_design_scores_gemma":[0.00007614357,0.0009605381,0.012388771,0.00002567887,0.00010504587,0.0028026407,0.0001443472,0.002416986,0.9674946,0.0007031657,0.012854929,0.000027041297],"about_ca_topic_score_codex":0.0014088216,"about_ca_topic_score_gemma":0.0018087124,"teacher_disagreement_score":0.0046420335,"about_ca_system_score_codex":0.0005696076,"about_ca_system_score_gemma":0.00040320682,"threshold_uncertainty_score":0.015529156},"labels":[],"label_agreement":null},{"id":"W4393189196","doi":"10.1172/jci178351","title":"IgG hexamers initiate complement-dependent acute lung injury","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; AABB Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Blood Foundation; University of California, San Francisco; National Institutes of Health","keywords":"Complement system; Antibody; Immunology; Medicine; Blocking antibody; Random hexamer; Cancer research; Biology; Molecular biology","score_opus":0.14414094659320312,"score_gpt":0.48469307831616787,"score_spread":0.3405521317229647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393189196","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908936,0.0015123051,0.0034755412,0.00014731892,0.000070136586,0.00017449631,0.00011616081,0.00020862496,0.003401814],"genre_scores_gemma":[0.9954692,0.00043796375,0.0015920753,0.0001751667,0.000021949036,0.00005630679,0.00012979055,0.000017476481,0.002100138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996494,0.00006593555,0.000026145988,0.00004832577,0.00010495363,0.00010527452],"domain_scores_gemma":[0.9998184,0.000038275426,0.000043393167,0.000022940465,0.000021747432,0.000055389508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031060932,0.0004721399,0.00033265472,0.0002701887,0.0001431217,0.00031044587,0.00017816883,0.00053670746,0.0016120287],"category_scores_gemma":[0.00019899786,0.00019058606,0.00030833483,0.00010673295,0.00033759797,0.0002186232,0.00026392489,0.0010143989,0.0004134923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033239086,0.00014615695,0.00022192254,0.000037436257,0.000007855474,0.00012410131,0.000020628198,0.00007337377,0.9971994,0.00013193092,0.00005446231,0.0016502755],"study_design_scores_gemma":[0.00009245308,0.0025675327,0.0032179116,0.000007675012,0.000017504559,0.00046017897,0.000019945435,0.0008560765,0.9915044,0.0001227378,0.0011297532,0.000003880822],"about_ca_topic_score_codex":0.00046863488,"about_ca_topic_score_gemma":0.00057838357,"teacher_disagreement_score":0.0016120287,"about_ca_system_score_codex":0.0004376647,"about_ca_system_score_gemma":0.00028740158,"threshold_uncertainty_score":0.00539279},"labels":[],"label_agreement":null},{"id":"W4393189307","doi":"10.1172/jci169470","title":"Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of British Columbia; Programs for Assessment of Technology in Health Research Institute; University of Toronto; University Health Network; Ontario Institute for Cancer Research","funders":"Ministerio de Economía y Competitividad; Deutsche Forschungsgemeinschaft; Canadian Institutes of Health Research; Government of Ontario; Conquer Cancer Foundation","keywords":"Biology; Cell biology; Proinflammatory cytokine; Cancer research; Extracellular vesicle; DNA damage; ETS transcription factor family; Ectopic expression; Innate immune system; Transcription factor; DNA; Genetics; Inflammation; microRNA; Gene; Immunology; Immune system; Microvesicles","score_opus":0.03041822540590592,"score_gpt":0.3389200280306967,"score_spread":0.30850180262479077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393189307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961319,0.0013796979,0.0012220754,0.00007364106,0.000019018542,0.000016062666,0.00017648615,0.000041962132,0.0009391299],"genre_scores_gemma":[0.9977652,0.0003043039,0.0004116707,0.000025066458,0.0000061627265,0.000011262288,0.00022878067,0.000006762257,0.0012406342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999095,0.000019582903,0.0000070063525,0.000014309037,0.000016632906,0.00003290302],"domain_scores_gemma":[0.9999503,0.000008601611,0.000013486805,0.0000050510066,0.000004916677,0.000017751638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012701674,0.00022219573,0.00008784,0.000104973435,0.00010981152,0.00022364377,0.000053380496,0.00016807546,0.0008794906],"category_scores_gemma":[0.00006338743,0.00009003408,0.00021050597,0.00006784946,0.00009865429,0.00015351803,0.0002353875,0.00026119282,0.00027729452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011110923,0.000011156457,0.00015230764,0.000014674484,0.0000028724546,0.00005155954,0.000008735951,0.000035467558,0.99904484,0.00010660892,0.000031925203,0.00042875332],"study_design_scores_gemma":[0.000026495161,0.0002688322,0.006800606,0.000005122854,0.000013312456,0.00042364874,0.00004023615,0.0010163028,0.9886382,0.00010460787,0.0026590037,0.0000035925589],"about_ca_topic_score_codex":0.00017579652,"about_ca_topic_score_gemma":0.00032898612,"teacher_disagreement_score":0.0008794906,"about_ca_system_score_codex":0.00017642438,"about_ca_system_score_gemma":0.00009357344,"threshold_uncertainty_score":0.0029422045},"labels":[],"label_agreement":null},{"id":"W4393930112","doi":"10.1172/jci171002","title":"Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Innate immune system; Biology; Immune system; Immunology; Inflammation; Haematopoiesis; Neutrophil extracellular traps; Pneumonia; Myeloid; Streptococcus pneumoniae; Medicine; Microbiology; Cell biology; Internal medicine; Stem cell","score_opus":0.04209777068351203,"score_gpt":0.31730763087559066,"score_spread":0.2752098601920786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393930112","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99829847,0.00044144652,0.0005837913,0.000054314125,0.000004452953,0.000008989123,0.00020365749,0.000020214422,0.00038469792],"genre_scores_gemma":[0.9990159,0.0001419828,0.00025240905,0.000019841167,0.0000034133943,0.000009532361,0.00012408456,0.000003767345,0.00042906796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988914,0.000026389138,0.000008751943,0.000024476425,0.00002785872,0.000023345257],"domain_scores_gemma":[0.9998223,0.000028732224,0.000067655994,0.000016513806,0.000015783196,0.000049018134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017522753,0.00020884625,0.00017517775,0.00020786902,0.00008774373,0.00029785564,0.000102640195,0.00016700386,0.0014220387],"category_scores_gemma":[0.00027494362,0.00008478153,0.00011518496,0.00009829107,0.0002233269,0.00011533124,0.00023045244,0.00027141612,0.00014393024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009928499,0.000059423975,0.046437792,0.000065398104,0.000025658575,0.00034464386,0.000056373523,0.00011489291,0.9432934,0.00016057958,0.00017275964,0.008276259],"study_design_scores_gemma":[0.00004445476,0.0009918271,0.79144967,0.000027823111,0.00005947972,0.0035486394,0.00012863705,0.001552987,0.19992043,0.00021466381,0.002046426,0.000015026915],"about_ca_topic_score_codex":0.0003876073,"about_ca_topic_score_gemma":0.00064415234,"teacher_disagreement_score":0.0014220387,"about_ca_system_score_codex":0.00012638212,"about_ca_system_score_gemma":0.00011289896,"threshold_uncertainty_score":0.0047572255},"labels":[],"label_agreement":null},{"id":"W4393993383","doi":"10.1172/jci173537","title":"Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Dental and Craniofacial Research; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; Pfizer Canada; Canada Excellence Research Chairs, Government of Canada; National Institutes of Health; Pfizer","keywords":"Neuropathic pain; Potassium channel; Cell biology; Pharmacology; Chronic pain; Chemistry; Endocrinology; Medicine; Neuroscience; Internal medicine; Biology","score_opus":0.07369710703688231,"score_gpt":0.3584973057605149,"score_spread":0.2848001987236326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393993383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99125165,0.0046685273,0.0019496296,0.00029577556,0.000039940096,0.000017019003,0.0004172005,0.00013907399,0.001221154],"genre_scores_gemma":[0.9942058,0.0021641392,0.0009929235,0.000111361354,0.000013453107,0.00001626003,0.00048740054,0.0000173101,0.0019912948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998728,0.000011469998,0.000008066013,0.000025976517,0.000023986897,0.00005762565],"domain_scores_gemma":[0.99994004,0.0000023300236,0.000023980847,0.000004256252,0.000008926937,0.000020471844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000723715,0.00035150745,0.00029089404,0.00020230278,0.00019243326,0.00024093903,0.00018503227,0.0002978187,0.0012976946],"category_scores_gemma":[0.00009724542,0.00011951262,0.00035551164,0.00015249575,0.00024166421,0.00023955436,0.00035278284,0.00047977513,0.00049670803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004669691,0.000018122631,0.0016435243,0.000103398044,0.000015428252,0.0003919769,0.000046445726,0.0001831716,0.9913414,0.00036937516,0.00021076067,0.00520938],"study_design_scores_gemma":[0.00013678096,0.001078696,0.060123734,0.000045307035,0.00018731058,0.0037600102,0.00044365323,0.004411867,0.9099777,0.0006895265,0.019107994,0.000037396578],"about_ca_topic_score_codex":0.0010786852,"about_ca_topic_score_gemma":0.0013222598,"teacher_disagreement_score":0.0012976946,"about_ca_system_score_codex":0.00042194157,"about_ca_system_score_gemma":0.00023814174,"threshold_uncertainty_score":0.004341185},"labels":[],"label_agreement":null},{"id":"W4394792404","doi":"10.1172/jci168536","title":"Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Veterinärmedizinische Universität Wien; St. Jude Children's Research Hospital; Academy of Finland; Austrian Science Fund; European Commission; Syöpäjärjestöt; Lymphoma Research Foundation","keywords":"T-cell receptor; T cell; Biology; STAT5; Cancer research; T-cell leukemia; Cell biology; ZAP70; Leukemia; Signal transduction; Immunology","score_opus":0.03173571434599548,"score_gpt":0.35226380040656247,"score_spread":0.320528086060567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394792404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99583626,0.00064208603,0.0015792776,0.0000777863,0.000019965975,0.000023917963,0.00063693064,0.00013818036,0.0010455694],"genre_scores_gemma":[0.99697924,0.0003372183,0.0008410443,0.00006308108,0.0000042080233,0.000017671537,0.0006112394,0.00002042468,0.001125799],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997781,0.000030565978,0.000021644139,0.00004599704,0.00006572141,0.000057956648],"domain_scores_gemma":[0.99993193,0.000011227057,0.000019227526,0.000008746792,0.0000043374657,0.000024609768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011151817,0.00023695112,0.00018872348,0.00024026755,0.00014639457,0.00036601129,0.00011784096,0.00021510872,0.0016479715],"category_scores_gemma":[0.000083251485,0.00011946624,0.00020019051,0.00022288233,0.00028426904,0.00012362211,0.00019718052,0.00072300556,0.00038592177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000112056776,0.000029541208,0.0008031412,0.000029808616,0.000006142826,0.00009104871,0.00001688748,0.000119697244,0.9968554,0.00016110051,0.00009046474,0.0016846744],"study_design_scores_gemma":[0.000035406927,0.0005063394,0.012351539,0.000010242203,0.000040854684,0.0010367165,0.00010154326,0.0016526704,0.9779749,0.00016796778,0.006114517,0.000007392408],"about_ca_topic_score_codex":0.00056781527,"about_ca_topic_score_gemma":0.0011570514,"teacher_disagreement_score":0.0016479715,"about_ca_system_score_codex":0.0004084465,"about_ca_system_score_gemma":0.00019631811,"threshold_uncertainty_score":0.0055130124},"labels":[],"label_agreement":null},{"id":"W4394853712","doi":"10.1172/jci170809","title":"The estrogen signaling pathway reprograms prostate cancer cell metabolism and supports proliferation and disease progression","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research","keywords":"Prostate cancer; Estrogen receptor; Cancer research; Biology; Estrogen receptor beta; Cell growth; Androgen receptor; Estrogen; Estrogen receptor alpha; Nuclear receptor; Cancer; Endocrinology; Breast cancer; Transcription factor; Genetics","score_opus":0.06051771547079411,"score_gpt":0.4157072906028091,"score_spread":0.355189575132015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394853712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95652634,0.024278192,0.0087157255,0.0008349504,0.00017637828,0.00005813876,0.0027463303,0.0004079318,0.00625593],"genre_scores_gemma":[0.98729634,0.006668582,0.001739821,0.00017632646,0.000026042853,0.000018145194,0.0010561679,0.000024784302,0.002993773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984646,0.00003836538,0.000007505601,0.000031821066,0.00004746075,0.000028392427],"domain_scores_gemma":[0.99994326,0.0000087995695,0.000011729442,0.0000070650176,0.000014777009,0.000014443238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001794751,0.00017610102,0.00026620846,0.0003372761,0.00014953666,0.0004834109,0.00011831284,0.00017600652,0.0016830588],"category_scores_gemma":[0.00014619899,0.0001181434,0.00024575062,0.00028944688,0.00015219592,0.00015893357,0.00022279013,0.00041433645,0.00039573017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026926456,0.00004706542,0.0015309486,0.0001608162,0.000022712602,0.00008919547,0.000033062654,0.0003845154,0.98173827,0.00040017854,0.000442967,0.014881014],"study_design_scores_gemma":[0.000039848273,0.00069154904,0.040561106,0.000044668737,0.0000902187,0.00080823875,0.00017317936,0.0026875788,0.9129403,0.00063304947,0.041299235,0.000031050353],"about_ca_topic_score_codex":0.00076377986,"about_ca_topic_score_gemma":0.0015284686,"teacher_disagreement_score":0.0016830588,"about_ca_system_score_codex":0.00025711991,"about_ca_system_score_gemma":0.000435928,"threshold_uncertainty_score":0.005630374},"labels":[],"label_agreement":null},{"id":"W4395031928","doi":"10.1172/jci166085","title":"Human NLRC4 expression promotes cancer survival and associates with type I interferon signaling and immune infiltration","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sante Montreal; Institut National de la Recherche Scientifique; McGill University","funders":"National Institute on Aging; Institut National Du Cancer; Université de Bordeaux","keywords":"Immune system; Infiltration (HVAC); Interferon; Cancer research; Signal transduction; Biology; Immunology; Interferon type I; Cancer; Cell biology; Genetics","score_opus":0.07714908873826772,"score_gpt":0.3681700378857463,"score_spread":0.2910209491474786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395031928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98995006,0.004190483,0.0038500724,0.00019217271,0.000020401922,0.00002334973,0.00045162207,0.00015708106,0.0011647075],"genre_scores_gemma":[0.99588615,0.0007449837,0.0013318434,0.000042025258,0.0000061651863,0.00002454931,0.0006272501,0.000015854157,0.0013210708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981636,0.0000309004,0.000016436137,0.000046505036,0.00004709439,0.00004269459],"domain_scores_gemma":[0.9998913,0.0000113939805,0.000050902854,0.000016306762,0.000014279496,0.00001574967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013609693,0.00024241491,0.0002133775,0.00022532717,0.000117302494,0.00026216282,0.00009752104,0.00028199967,0.0012241366],"category_scores_gemma":[0.00016471531,0.000106030966,0.00023742601,0.00018024597,0.00023237446,0.0001390838,0.0001579954,0.00034662435,0.00032632254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020606823,0.000015035001,0.0013795485,0.000036890688,0.000007871795,0.000040946965,0.000012027323,0.00008469049,0.9961732,0.000046356043,0.00005965873,0.0019377769],"study_design_scores_gemma":[0.00003127041,0.00039292587,0.026809083,0.000010352207,0.000040102906,0.0008332369,0.000048934955,0.0019916454,0.96342725,0.00011096308,0.006296009,0.000008330092],"about_ca_topic_score_codex":0.0004786815,"about_ca_topic_score_gemma":0.00047484774,"teacher_disagreement_score":0.0012241366,"about_ca_system_score_codex":0.000428215,"about_ca_system_score_gemma":0.00017400163,"threshold_uncertainty_score":0.004095137},"labels":[],"label_agreement":null},{"id":"W4395050642","doi":"10.1172/jci167371","title":"Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes; Athletic Edge Sports Medicine","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; National Institute on Aging; National Institute of General Medical Sciences; American Heart Association; Howard Hughes Medical Institute","keywords":"Metabolism; Skeletal muscle; Endocrinology; Internal medicine; Chemistry; Energy metabolism; Biology; Medicine","score_opus":0.08233400625998226,"score_gpt":0.40860817939056776,"score_spread":0.3262741731305855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395050642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882388,0.000961716,0.006471812,0.0004240274,0.00012360384,0.00019472111,0.0012398311,0.00054181257,0.0018036193],"genre_scores_gemma":[0.97509843,0.0016903592,0.008576091,0.0004358188,0.00006862217,0.0008912027,0.0024134775,0.00022739012,0.010598673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938965,0.00011828969,0.00008344519,0.000174521,0.000089889356,0.00014421102],"domain_scores_gemma":[0.9995171,0.00004624812,0.00017169175,0.000077874305,0.00003271486,0.00015429204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052400265,0.0011343932,0.00044389116,0.0014455444,0.00041127292,0.0006832282,0.0005198343,0.00088653824,0.0030145582],"category_scores_gemma":[0.00024072778,0.0005373158,0.00075420726,0.00042068973,0.00092629396,0.0003885651,0.0005595573,0.0016724205,0.00060925935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079322874,0.0004227355,0.0007442724,0.000051480227,0.00002085495,0.00016009079,0.000073528536,0.000074556774,0.9952873,0.00025611877,0.00012513877,0.0019906093],"study_design_scores_gemma":[0.0005646759,0.007348748,0.031594563,0.00012652115,0.00016276588,0.0014729375,0.00025658787,0.0029292693,0.94648343,0.0003912722,0.008623156,0.00004592109],"about_ca_topic_score_codex":0.00079389894,"about_ca_topic_score_gemma":0.0018786285,"teacher_disagreement_score":0.0030145582,"about_ca_system_score_codex":0.00048224535,"about_ca_system_score_gemma":0.00038769192,"threshold_uncertainty_score":0.010084748},"labels":[],"label_agreement":null},{"id":"W4396507749","doi":"10.1172/jci176640","title":"Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"COVID-19 epidemiological studies","field":"Mathematics","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Prevention of Organ Failure; University of British Columbia","funders":"National Center for Advancing Translational Sciences; National Institute on Drug Abuse; National Institute on Alcohol Abuse and Alcoholism; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation; National Institutes of Health; National Science Foundation","keywords":"Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Medicine; Immune system; Pandemic; Immunology; Virology; Intensive care medicine; Internal medicine; Disease; Infectious disease (medical specialty); Outbreak","score_opus":0.49407827762245166,"score_gpt":0.5325399380350666,"score_spread":0.03846166041261495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396507749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907646,0.0008610016,0.0029935646,0.00036013196,0.000027003663,0.00006220134,0.0043666847,0.000039132294,0.000525601],"genre_scores_gemma":[0.9912417,0.00026503028,0.001978979,0.00021094235,0.000038241724,0.00010085888,0.005810871,0.000014326648,0.00033905517],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993376,0.00025642512,0.000036134006,0.0001877881,0.000067172754,0.0001148781],"domain_scores_gemma":[0.99889106,0.00015594011,0.0003944869,0.00017752979,0.00018560249,0.00019530064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017699341,0.00051734864,0.0005400847,0.00055037707,0.00037340494,0.0008645436,0.00039603098,0.00041397443,0.0011714342],"category_scores_gemma":[0.0018287227,0.00023443312,0.00070416933,0.00069196016,0.00021834031,0.00041207,0.0013250539,0.00090128696,0.0001820242],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011405438,0.00014115132,0.986311,0.00005421345,0.0005801261,0.00009881702,0.00009839058,0.00063415087,0.0029260404,0.00018965316,0.0011314674,0.006694417],"study_design_scores_gemma":[0.000055712117,0.0004229032,0.9905691,0.000034305176,0.00033155247,0.00020390542,0.00020066493,0.0054112044,0.00083488796,0.0005572697,0.0013575836,0.000020872527],"about_ca_topic_score_codex":0.003294299,"about_ca_topic_score_gemma":0.0040112208,"teacher_disagreement_score":0.003294299,"about_ca_system_score_codex":0.0004643936,"about_ca_system_score_gemma":0.000672966,"threshold_uncertainty_score":0.009360373},"labels":[],"label_agreement":null},{"id":"W4396529686","doi":"10.1172/jci180512","title":"Enhancing anticancer activity of macrophages through rational drug combinations","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"National Cancer Institute; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke","keywords":"Drug; Anticancer drug; Pharmacology; Chemistry; Computational biology; Biology","score_opus":0.05411144145638554,"score_gpt":0.38596242424813554,"score_spread":0.33185098279175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396529686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8419737,0.065248854,0.033007342,0.009186984,0.0020165686,0.0016601601,0.001015766,0.0011703711,0.044720232],"genre_scores_gemma":[0.9466168,0.027084565,0.014721775,0.0015848046,0.0001840794,0.00035538824,0.00039564725,0.00007191542,0.008985001],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998099,0.000043102114,0.000013759956,0.000032743053,0.0000587991,0.00004182871],"domain_scores_gemma":[0.9999261,0.000017096309,0.000015578917,0.000009125747,0.000015593854,0.000016455571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003669871,0.0005123031,0.00045781297,0.0005565478,0.00019836589,0.0007192009,0.00038576912,0.00044602106,0.0016424983],"category_scores_gemma":[0.00027330316,0.00026644257,0.00036604545,0.00024737598,0.0003125854,0.00040180972,0.00035926522,0.0010171371,0.00053548877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015454186,0.001654305,0.00085100223,0.00066970056,0.0001804592,0.00060328207,0.0001384455,0.005700947,0.78962916,0.0107768215,0.010057742,0.17819262],"study_design_scores_gemma":[0.0022557625,0.00900958,0.0019805883,0.00014185648,0.00034026452,0.001527692,0.00010360701,0.012430338,0.7605533,0.0037894812,0.20776567,0.000101843165],"about_ca_topic_score_codex":0.00019410856,"about_ca_topic_score_gemma":0.001070948,"teacher_disagreement_score":0.0016424983,"about_ca_system_score_codex":0.0004253742,"about_ca_system_score_gemma":0.0002755296,"threshold_uncertainty_score":0.005494714},"labels":[],"label_agreement":null},{"id":"W4396530381","doi":"10.1172/jci176474","title":"Induction of antiviral interferon-stimulated genes by neuronal STING promotes the resolution of pain in mice","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Children's Hospital Research Institute; Crohn's and Colitis Canada; Agence Nationale de la Recherche; Canadian Association of Gastroenterology","keywords":"Sting; Stimulator of interferon genes; Nociceptor; Inflammation; Dorsal root ganglion; Hyperalgesia; Nociception; Interferon; Cell biology; Medicine; Immunology; Neuroscience; Biology; Receptor; Spinal cord; Innate immune system; Immune system; Internal medicine","score_opus":0.06284313801702422,"score_gpt":0.3483504577478099,"score_spread":0.2855073197307857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396530381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926649,0.0010202762,0.0029983355,0.0002851442,0.000055417182,0.00006011005,0.00079554203,0.0002667796,0.0018534871],"genre_scores_gemma":[0.9903053,0.0007325188,0.003741825,0.0001819436,0.000022356608,0.00012037475,0.0006866329,0.00007760795,0.0041315677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996259,0.00006867517,0.00004608083,0.00007857886,0.00006823905,0.000112403904],"domain_scores_gemma":[0.9996394,0.0000417998,0.00013640456,0.000038851726,0.000018474191,0.00012508844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034207423,0.00058563426,0.0003303618,0.0008754911,0.00022113536,0.00044437486,0.0003481441,0.00065679394,0.0023246517],"category_scores_gemma":[0.00019360006,0.00033749276,0.0004482199,0.00025510782,0.0006618905,0.0003914211,0.0002648558,0.0017807209,0.0005010821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006134679,0.00018701151,0.0003339645,0.000038889862,0.000008705427,0.00006718631,0.000033359032,0.00008165216,0.99685764,0.00021857773,0.000066487846,0.001493027],"study_design_scores_gemma":[0.00019947458,0.0018998561,0.0075049954,0.000044345124,0.000038686252,0.00045599721,0.00009450491,0.0022358242,0.9850152,0.00026045757,0.002239655,0.00001110303],"about_ca_topic_score_codex":0.00040084828,"about_ca_topic_score_gemma":0.00076459354,"teacher_disagreement_score":0.0023246517,"about_ca_system_score_codex":0.00054074835,"about_ca_system_score_gemma":0.00030642212,"threshold_uncertainty_score":0.0077766776},"labels":[],"label_agreement":null},{"id":"W4396530801","doi":"10.1172/jci177726","title":"Gravi-D peptide disrupts HDAC11 association with an AKAP to stimulate adipocyte thermogenic signaling","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Colorado Clinical and Translational Sciences Institute; American Heart Association","keywords":"Adipocyte; Association (psychology); Cell biology; Internal medicine; Chemistry; Endocrinology; Biology; Psychology; Medicine; Adipose tissue","score_opus":0.07358004837821382,"score_gpt":0.4000688432518195,"score_spread":0.3264887948736057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396530801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98969716,0.0020128451,0.0020308802,0.00058063,0.0004712682,0.00011129436,0.0013794091,0.00015628197,0.0035603736],"genre_scores_gemma":[0.99238825,0.0006524102,0.00202615,0.00020995275,0.000042394415,0.00008303867,0.00086878217,0.000031731153,0.00369728],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993932,0.000080299345,0.00007745007,0.00016629545,0.0001072855,0.00017544595],"domain_scores_gemma":[0.9997892,0.000030777857,0.000052575306,0.000022585784,0.000011195251,0.000093765404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003574646,0.0005297526,0.0004442893,0.00024444854,0.00047737287,0.00046680335,0.0005224287,0.00056975015,0.005670583],"category_scores_gemma":[0.00021573847,0.00037608607,0.00053443987,0.00021320464,0.00084074517,0.00028385792,0.00039563305,0.001987272,0.0012328011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017789591,0.00024304673,0.00047101817,0.00007521765,0.000047041907,0.0001202103,0.000027100365,0.00015751786,0.99457717,0.0002594055,0.0003694646,0.0018739428],"study_design_scores_gemma":[0.000489572,0.0014170173,0.0042771655,0.0000090625945,0.000053908796,0.0003927091,0.00009104266,0.0006720951,0.98785377,0.000060853275,0.0046645305,0.000018308498],"about_ca_topic_score_codex":0.0012850466,"about_ca_topic_score_gemma":0.0029490076,"teacher_disagreement_score":0.005670583,"about_ca_system_score_codex":0.0007901332,"about_ca_system_score_gemma":0.0006425532,"threshold_uncertainty_score":0.018969953},"labels":[],"label_agreement":null},{"id":"W4396905245","doi":"10.1172/jci176910","title":"Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Toronto; University of Victoria; University of Saskatchewan; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Remyelination; Multiple sclerosis; Oligodendrocyte; Myelin; Biology; Neuroscience; Extracellular matrix; Regeneration (biology); Immunology; Medicine; Central nervous system; Cell biology","score_opus":0.09745320419922626,"score_gpt":0.383863121787192,"score_spread":0.28640991758796575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396905245","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9410902,0.040008526,0.0062765013,0.0007589484,0.00022966719,0.00020645747,0.000996378,0.00030901446,0.01012438],"genre_scores_gemma":[0.98072034,0.0067117694,0.0045486884,0.0003120898,0.00006096612,0.00010939638,0.0011870394,0.000021709013,0.006328018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999913,0.000017682598,0.000009107206,0.000017540558,0.000024727777,0.00001802692],"domain_scores_gemma":[0.99995434,0.0000063600814,0.000014313842,0.0000033520519,0.000008174719,0.000013401035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021201085,0.00064847583,0.00028823575,0.00044833717,0.00026997624,0.00026198768,0.00014827313,0.0004052561,0.0011253983],"category_scores_gemma":[0.00015380257,0.0001114969,0.0001699364,0.00017749533,0.00023504123,0.00009508457,0.00018189495,0.00032786926,0.00036698766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002315435,0.000036589725,0.00081408926,0.00011562274,0.00002383738,0.0004319779,0.000012746156,0.00012319213,0.99068344,0.00024003236,0.00034751638,0.0069393534],"study_design_scores_gemma":[0.0000995946,0.0014441286,0.023087963,0.000048648228,0.000101904414,0.005626398,0.000043890614,0.0012085736,0.94047415,0.00033828305,0.02750374,0.0000227606],"about_ca_topic_score_codex":0.0011246299,"about_ca_topic_score_gemma":0.001637981,"teacher_disagreement_score":0.0011253983,"about_ca_system_score_codex":0.00038699366,"about_ca_system_score_gemma":0.00032588324,"threshold_uncertainty_score":0.0037648082},"labels":[],"label_agreement":null},{"id":"W4398155824","doi":"10.1172/jci180012","title":"Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; Janssen Biotech; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Gilead Sciences; National Cancer Institute; National Institute on Aging; Eurostars; Larry L. Hillblom Foundation; Genentech; Celgene; Centers for Disease Control and Prevention; University of California, San Francisco; Swedish Orphan Biovitrum; Springworks Therapeutics; Rare Diseases Clinical Research Network; National Institute of Allergy and Infectious Diseases; Angiocrine Bioscience; Alexion Pharmaceuticals; Kite Pharma; Bristol-Myers Squibb; National Institutes of Health; Legend Biotech; Argenx; GlaxoSmithKline; Amgen; National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Sanofi; MorphoSys; Juno Therapeutics","keywords":"Autoantibody; Autoimmunity; Immunology; Proteome; Computational biology; Epitope; Medicine; Disease; Antibody; Biology; Bioinformatics; Internal medicine","score_opus":0.14900847362975833,"score_gpt":0.45288601287909586,"score_spread":0.3038775392493375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398155824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812547,0.003343462,0.013408297,0.00010369392,0.000032370346,0.000055393473,0.0005377882,0.00012946286,0.0011347682],"genre_scores_gemma":[0.98811114,0.0018608421,0.008559135,0.00015641366,0.000023547374,0.00005287766,0.0004949874,0.000027530063,0.00071353],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997938,0.000048400005,0.000015361238,0.00004719368,0.00006128051,0.000034002514],"domain_scores_gemma":[0.9998802,0.000032768843,0.000029254066,0.000019552526,0.000019713585,0.000018557264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044709523,0.00029667723,0.00031756543,0.0003827565,0.00014883777,0.00050730497,0.00013445078,0.00023119962,0.000731875],"category_scores_gemma":[0.00022510362,0.00012076452,0.00019922586,0.0001929407,0.00020194084,0.0003152535,0.00025558306,0.00060437864,0.00017757676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000921218,0.000032748638,0.00087117625,0.000047634127,0.00001719814,0.00001893447,0.000015902266,0.0002593262,0.99354035,0.000069063586,0.00003575046,0.004999797],"study_design_scores_gemma":[0.0000163281,0.00078666175,0.025802536,0.000014528346,0.00005787103,0.00044753635,0.00006597404,0.0035494943,0.9658323,0.0002450831,0.003170468,0.000011163334],"about_ca_topic_score_codex":0.00015353589,"about_ca_topic_score_gemma":0.00039214586,"teacher_disagreement_score":0.000731875,"about_ca_system_score_codex":0.00014782831,"about_ca_system_score_gemma":0.00017677362,"threshold_uncertainty_score":0.00244838},"labels":[],"label_agreement":null},{"id":"W4398765485","doi":"10.1172/jci180080","title":"Spatial and functional targeting of intratumoral Tregs reverses CD8+ T cell exhaustion and promotes cancer immunotherapy","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Cancer Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Pelotonia; Eli Lilly and Company","keywords":"Immunotherapy; Cancer immunotherapy; CD8; Cancer research; Cytotoxic T cell; Immunology; Cancer; Medicine; Biology; Immune system; Internal medicine; Genetics","score_opus":0.04793135724547782,"score_gpt":0.3479394220882325,"score_spread":0.30000806484275466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398765485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99164855,0.0016145931,0.0040261433,0.00017868898,0.00008787444,0.00005092801,0.00012982146,0.0002567611,0.0020066674],"genre_scores_gemma":[0.99667466,0.00041318216,0.0011253173,0.00005417822,0.00002264657,0.000035254106,0.00009948331,0.000018563831,0.0015565385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998473,0.000021286754,0.000011568573,0.000025807994,0.000037399164,0.000056576115],"domain_scores_gemma":[0.99994123,0.0000065845916,0.000017792374,0.000009322053,0.0000050770977,0.000019952337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104675855,0.0003439124,0.00030339282,0.0001905085,0.000094467665,0.00023122982,0.00017996844,0.00025897496,0.0007405543],"category_scores_gemma":[0.000081312806,0.00010121193,0.0001686645,0.00008974581,0.00022750798,0.00016049853,0.00018116225,0.0011039927,0.0002548691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021871936,0.00015658082,0.000096239775,0.000043966244,0.00000506345,0.00003589081,0.000012472925,0.00017809098,0.9938923,0.00016956893,0.00009778638,0.005093291],"study_design_scores_gemma":[0.00013408535,0.0017893588,0.0020048183,0.000011893956,0.000036879523,0.00040090055,0.0000380209,0.0025587052,0.9876687,0.0001961557,0.005153532,0.0000069893094],"about_ca_topic_score_codex":0.00015389074,"about_ca_topic_score_gemma":0.00032917937,"teacher_disagreement_score":0.0007405543,"about_ca_system_score_codex":0.00012094084,"about_ca_system_score_gemma":0.00018874471,"threshold_uncertainty_score":0.0024774075},"labels":[],"label_agreement":null},{"id":"W4399391820","doi":"10.1172/jci177142","title":"Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"National Cancer Institute; National Institutes of Health","keywords":"Allosteric regulation; Autophagy; MAPK/ERK pathway; Cancer research; Kinase; Signal transduction; Cancer; Biology; Enzyme; Cell biology; Biochemistry; Genetics","score_opus":0.040283755030534614,"score_gpt":0.36921816522349443,"score_spread":0.3289344101929598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399391820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828977,0.0058470457,0.0030588096,0.00025521836,0.000055012857,0.000046168723,0.0001543271,0.00014055784,0.0075450293],"genre_scores_gemma":[0.9957985,0.0017046584,0.0007899889,0.00006520361,0.000011842602,0.000015044633,0.00009659509,0.000009770813,0.0015082833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999354,0.000013294772,0.000005135597,0.000009514066,0.000018276705,0.000018480438],"domain_scores_gemma":[0.99996674,0.000008456757,0.0000076226124,0.0000054619986,0.0000041416242,0.0000075296834],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014878357,0.00022905899,0.00022011345,0.00016008875,0.0001206448,0.00025243137,0.00013035124,0.00017131734,0.0014079403],"category_scores_gemma":[0.00009515795,0.00007761844,0.00016774819,0.00011116981,0.00015733782,0.00017152884,0.00017545273,0.0005762727,0.00021914848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048189677,0.00030131996,0.0008794533,0.00016271418,0.000020587613,0.00016040722,0.000033062843,0.0006871349,0.96101415,0.0011391701,0.00047065332,0.03464938],"study_design_scores_gemma":[0.00006251293,0.0013482289,0.005897027,0.00001454141,0.000040873776,0.0006800035,0.000027574726,0.0025089602,0.97979134,0.00027604736,0.00934425,0.00000873854],"about_ca_topic_score_codex":0.00014627722,"about_ca_topic_score_gemma":0.0005504159,"teacher_disagreement_score":0.0014079403,"about_ca_system_score_codex":0.00014383433,"about_ca_system_score_gemma":0.00016228038,"threshold_uncertainty_score":0.0047100782},"labels":[],"label_agreement":null},{"id":"W4399625542","doi":"10.1172/jci165814","title":"C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Medical Research Council; Associazione Italiana per la Ricerca sul Cancro; NextGenerationEU; Ministero della Salute; National Institute on Aging; Deutsche Forschungsgemeinschaft; Wellcome Trust; Francis Crick Institute; National Institutes of Health; Cancer Research UK; Fondazione AIRC per la ricerca sul cancro ETS","keywords":"Autophagy; Biology; Caenorhabditis elegans; Downregulation and upregulation; Cell biology; Senescence; Gene; Ageing; Oxidative stress; Autophagosome; Genetics; Apoptosis; Biochemistry","score_opus":0.04318521805413236,"score_gpt":0.3534587506719208,"score_spread":0.31027353261778845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399625542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953963,0.00070912373,0.0015164429,0.00010932954,0.00004886443,0.000035370063,0.0007446997,0.00019257981,0.0012472944],"genre_scores_gemma":[0.99284416,0.00047972603,0.0025566253,0.00006270699,0.000009459677,0.000051315477,0.0006655733,0.00005645424,0.0032738396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999025,0.00000834957,0.0000107002625,0.00003612899,0.000019930645,0.00002239615],"domain_scores_gemma":[0.99980754,0.00001586816,0.00006840628,0.000019842275,0.000013554271,0.00007479004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016333368,0.0003720419,0.00021549198,0.00042979314,0.00022260325,0.00019255365,0.00023642597,0.0002928751,0.0015730537],"category_scores_gemma":[0.0001399249,0.00014931012,0.00024059492,0.000078366786,0.00039835036,0.0001522441,0.0003107669,0.00036963986,0.0003022167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012779096,0.000026078988,0.00038959304,0.000042430285,0.0000047130243,0.00009790151,0.000009251973,0.00006879579,0.99758804,0.00009918164,0.00007646263,0.0014697039],"study_design_scores_gemma":[0.000049409704,0.00044648635,0.021715801,0.000032500422,0.000024206636,0.0005480507,0.000043467273,0.001506456,0.97044086,0.00013631246,0.0050418065,0.000014700183],"about_ca_topic_score_codex":0.0008305574,"about_ca_topic_score_gemma":0.0019623095,"teacher_disagreement_score":0.0015730537,"about_ca_system_score_codex":0.00028048948,"about_ca_system_score_gemma":0.0002994313,"threshold_uncertainty_score":0.005262375},"labels":[],"label_agreement":null},{"id":"W4399727957","doi":"10.1172/jci171136","title":"Triptolide and its prodrug Minnelide target high-risk MYC-amplified medulloblastoma in preclinical models","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Natural Compounds in Disease Treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; Vince Lombardi Cancer Foundation; Hollings Cancer Center, Medical University of South Carolina; National Institutes of Health; Southeastern Brain Tumor Foundation; American Lebanese Syrian Associated Charities; Foundation for the National Institutes of Health; American Cancer Society; Alex's Lemonade Stand Foundation for Childhood Cancer; V Foundation for Cancer Research; College of Graduate Studies, Medical University of South Carolina; Rally Foundation; Southern Regional Education Board","keywords":"Triptolide; Medulloblastoma; Cancer research; In vivo; Medicine; Drug; Pharmacology; Toxicity; Oncology; Internal medicine; Biology; Apoptosis","score_opus":0.10741417624192191,"score_gpt":0.41141428999345653,"score_spread":0.30400011375153463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399727957","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898992,0.0021200248,0.0032389327,0.0001990298,0.000043278204,0.00019530086,0.0019981782,0.00014902905,0.0021569843],"genre_scores_gemma":[0.9890103,0.0024265018,0.004463257,0.000094797215,0.000010914459,0.00014864381,0.001892523,0.000022578284,0.0019304532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993443,0.000008963775,0.0000057460034,0.000014798935,0.000020062946,0.000016032196],"domain_scores_gemma":[0.9999497,0.000008297564,0.00001528884,0.00000514391,0.0000062699214,0.00001528129],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013054081,0.00031881308,0.00032076184,0.00031345803,0.00010948896,0.00025330824,0.00021169534,0.0002632491,0.001450814],"category_scores_gemma":[0.000096887125,0.00012870302,0.0002446929,0.00014612665,0.00018354763,0.00024375683,0.00010554153,0.0006960532,0.00025247326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011911262,0.00034026388,0.0006730845,0.0001938571,0.000030456424,0.000090700225,0.000023274824,0.001087901,0.9861092,0.00025314497,0.00037647388,0.009630491],"study_design_scores_gemma":[0.00020159845,0.0066057383,0.004028379,0.000018413702,0.00006246575,0.0003217868,0.000034140285,0.002673049,0.97875494,0.00015685013,0.0071316496,0.00001100993],"about_ca_topic_score_codex":0.0008201251,"about_ca_topic_score_gemma":0.0024229183,"teacher_disagreement_score":0.001450814,"about_ca_system_score_codex":0.0004584892,"about_ca_system_score_gemma":0.00031581213,"threshold_uncertainty_score":0.0048534274},"labels":[],"label_agreement":null},{"id":"W4401169155","doi":"10.1172/jci168789","title":"Human milk antibodies to global pathogens reveal geographic and interindividual variations in IgA and IgG","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Medical Center, University of Rochester; University of Rochester; Bill and Melinda Gates Foundation","keywords":"Antibody; Immunology; Immunoglobulin A; Immunoglobulin G; Biology; Virology","score_opus":0.10409614740750149,"score_gpt":0.451682176189402,"score_spread":0.3475860287819005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401169155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986162,0.0005278199,0.00021099148,0.000021247533,0.0000023201849,0.0000022944905,0.0002610329,0.000006027602,0.0003521898],"genre_scores_gemma":[0.99923444,0.00015882516,0.00017290447,0.000026426014,0.0000034621362,0.0000043930013,0.00022859745,0.0000024475416,0.0001683787],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997311,0.000045265304,0.000014287955,0.000105343286,0.000046284276,0.00005768819],"domain_scores_gemma":[0.9996056,0.000092680464,0.00018474845,0.000038192138,0.000046365716,0.000032548953],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037763017,0.00019639845,0.00020800978,0.00057467667,0.00013256793,0.0004189566,0.0001156891,0.00023843553,0.0012864321],"category_scores_gemma":[0.0006281281,0.0001509875,0.00015790488,0.00062001444,0.00019441028,0.00017190282,0.00031323815,0.00018690745,0.00021829658],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000289518,0.000020036234,0.94863665,0.000042967604,0.00020240607,0.000055055232,0.00024575408,0.000109747154,0.04043809,0.00004270607,0.00017335278,0.009743722],"study_design_scores_gemma":[0.0000015260473,0.00005275906,0.9980558,0.0000025467361,0.000018123237,0.00010326029,0.000100205456,0.000055935892,0.0013344154,0.000027101376,0.00024694856,0.0000013538545],"about_ca_topic_score_codex":0.0016166298,"about_ca_topic_score_gemma":0.0015573849,"teacher_disagreement_score":0.0016166298,"about_ca_system_score_codex":0.0001627825,"about_ca_system_score_gemma":0.00008288947,"threshold_uncertainty_score":0.004303515},"labels":[],"label_agreement":null},{"id":"W4401169446","doi":"10.1172/jci176344","title":"Convergent generation of atypical prions in knockin mouse models of genetic prion disease","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Public Health Agency of Canada; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Disease; Biology; Virology; Genetics; Medicine; Pathology","score_opus":0.09644045760926259,"score_gpt":0.36954299019667064,"score_spread":0.273102532587408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401169446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98750454,0.0012083186,0.009431571,0.00014054058,0.00003499773,0.000100637815,0.00033664505,0.00020746894,0.001035209],"genre_scores_gemma":[0.9875572,0.0011986987,0.008815135,0.00010222691,0.00001782693,0.00012529406,0.00053729495,0.000071191935,0.0015753246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995883,0.00010076297,0.00006673886,0.00009833254,0.00010092772,0.000044896435],"domain_scores_gemma":[0.999542,0.0000897575,0.0001334767,0.00007420275,0.000030350226,0.00013028155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061530387,0.00059292355,0.00039607155,0.0008651147,0.00019170676,0.00044577962,0.00034393847,0.0005863025,0.0006647852],"category_scores_gemma":[0.00042165647,0.00032954078,0.00028336095,0.00020305722,0.0005691284,0.0004243222,0.00043248778,0.0008969001,0.0002620129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018513651,0.00008570415,0.00046441556,0.00004031583,0.000014755844,0.00028802938,0.000040848052,0.000112240545,0.9972197,0.0004056867,0.00004914423,0.0010940428],"study_design_scores_gemma":[0.0002129076,0.0024943475,0.01527944,0.00008209227,0.00008691801,0.008171902,0.0000974934,0.004660728,0.96228015,0.0017614481,0.0048345104,0.00003795696],"about_ca_topic_score_codex":0.0001834341,"about_ca_topic_score_gemma":0.00046989162,"teacher_disagreement_score":0.0008651147,"about_ca_system_score_codex":0.00027646427,"about_ca_system_score_gemma":0.00014365972,"threshold_uncertainty_score":0.003254056},"labels":[],"label_agreement":null},{"id":"W4401567774","doi":"10.1172/jci168393","title":"MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"NIH Office of the Director; National Cancer Institute; National Heart, Lung, and Blood Institute; Cystic Fibrosis Foundation","keywords":"Mesenchymal stem cell; Phosphorylation; Lung; Transformation (genetics); Cancer research; Cell biology; Medicine; Biology; Immunology; Internal medicine; Gene; Biochemistry","score_opus":0.047008966133106705,"score_gpt":0.3711199469621919,"score_spread":0.3241109808290852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401567774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99713457,0.0015565716,0.00072126376,0.000057696667,0.0000147120245,0.000009335199,0.000086590495,0.000019469979,0.00039969565],"genre_scores_gemma":[0.99848086,0.00051726226,0.00026155467,0.00001882987,0.0000068540357,0.00000916874,0.000079314,0.0000016856295,0.0006243695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999422,0.000008517625,0.0000063167904,0.0000135042765,0.000012805605,0.000016661408],"domain_scores_gemma":[0.999956,0.0000039456677,0.00002088929,0.0000034285856,0.000003806164,0.000011987305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079487465,0.00021353828,0.0001216365,0.00013132837,0.00013989343,0.00015674933,0.00006763371,0.00014234862,0.00078339735],"category_scores_gemma":[0.00006737923,0.000077714285,0.00015334848,0.00006916602,0.00020580912,0.000108005166,0.00013656856,0.00031694293,0.0001276295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004204958,0.000050387145,0.0026868787,0.000048849004,0.000007664236,0.00017576061,0.000016519598,0.000058417678,0.9946912,0.000106362204,0.00004548064,0.0016919586],"study_design_scores_gemma":[0.000053632204,0.0006942022,0.1939637,0.000014121898,0.000041410567,0.0018912577,0.00013478841,0.0016132628,0.7977714,0.00023801358,0.0035756335,0.0000085672755],"about_ca_topic_score_codex":0.0002220682,"about_ca_topic_score_gemma":0.00042065338,"teacher_disagreement_score":0.00078339735,"about_ca_system_score_codex":0.00018437082,"about_ca_system_score_gemma":0.00012208935,"threshold_uncertainty_score":0.002620697},"labels":[],"label_agreement":null},{"id":"W4402042938","doi":"10.1172/jci180983","title":"Parkin activates innate immunity and promotes antitumor immune responses","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"U.S. National Library of Medicine; National Cancer Institute; National Institutes of Health","keywords":"Parkin; Biology; Ubiquitin ligase; Tumor microenvironment; Innate immune system; Cell biology; Cytotoxic T cell; Immune system; Cancer research; Immunology; Ubiquitin; Medicine","score_opus":0.06627815754238557,"score_gpt":0.37380248209177835,"score_spread":0.30752432454939277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402042938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919646,0.003990328,0.0015389163,0.00015439796,0.00002277809,0.000017711382,0.000067029985,0.00006569032,0.0021785153],"genre_scores_gemma":[0.9979565,0.0006113133,0.00041130444,0.000029152294,0.0000112198895,0.000007669097,0.00004094253,0.0000033379674,0.0009286194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992406,0.000021196962,0.00000552757,0.000013404695,0.000013689952,0.000022085625],"domain_scores_gemma":[0.9999491,0.0000073402384,0.00001520531,0.000005712442,0.0000046080054,0.000017987884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012817406,0.00018056679,0.00014548821,0.00011399915,0.000074995616,0.00019692311,0.000047434383,0.00010917212,0.0010334245],"category_scores_gemma":[0.00007727296,0.00005089405,0.00007558644,0.00005227639,0.0001283623,0.00010856389,0.00015369306,0.00033513215,0.00016795851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002464184,0.000046509667,0.0008404831,0.000042074356,0.0000037192422,0.000085539876,0.000016984623,0.0000533473,0.99267393,0.00024412796,0.000063316875,0.0056836316],"study_design_scores_gemma":[0.00006762854,0.0011384021,0.013659381,0.000017588169,0.000020141102,0.0008189405,0.00005777833,0.0009963375,0.97497934,0.00031501867,0.007925482,0.000004014698],"about_ca_topic_score_codex":0.00003819606,"about_ca_topic_score_gemma":0.00011353321,"teacher_disagreement_score":0.0010334245,"about_ca_system_score_codex":0.000110734545,"about_ca_system_score_gemma":0.000091720685,"threshold_uncertainty_score":0.003457129},"labels":[],"label_agreement":null},{"id":"W4402124489","doi":"10.1172/jci178573","title":"Increased risk of kidney failure in patients with genetic kidney disorders","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Center for Advancing Translational Sciences; U.S. National Library of Medicine; Nephcure Foundation; National Human Genome Research Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Kidney; Medicine; Bioinformatics; Internal medicine; Biology; Intensive care medicine","score_opus":0.015145127358249572,"score_gpt":0.30380907595398515,"score_spread":0.2886639485957356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402124489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99884295,0.000364473,0.00006260949,0.00007418523,0.0000053392228,0.0000030491913,0.00025833893,0.0000052337414,0.00038372207],"genre_scores_gemma":[0.99952555,0.0000963309,0.00006623834,0.000033775716,0.000013611061,0.0000020305417,0.00020064239,0.0000013474695,0.000060552164],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9995384,0.00009578405,0.000035579935,0.00014353516,0.00009437958,0.000092251415],"domain_scores_gemma":[0.99842936,0.00027559628,0.0008188895,0.00010408787,0.00010691016,0.00026516928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053296867,0.00022831981,0.00034660185,0.0006876414,0.0005280967,0.0005844964,0.00029415172,0.00040010636,0.0018499963],"category_scores_gemma":[0.001877907,0.00015562907,0.0004448932,0.0008215671,0.00032483635,0.00030245967,0.00049025536,0.0006118346,0.00011480063],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005450383,0.000006360562,0.99899846,0.0000039002775,0.00002644667,0.00011345099,0.000012159836,0.000027144155,0.000101291145,0.000015722468,0.00004191934,0.00059863774],"study_design_scores_gemma":[0.00000415623,0.00002917981,0.99872607,0.0000040453024,0.00002115066,0.00089773745,0.000033876488,0.000103766215,0.000041305313,0.00005606107,0.00008038392,0.0000023313733],"about_ca_topic_score_codex":0.0038269004,"about_ca_topic_score_gemma":0.0041645016,"teacher_disagreement_score":0.0038269004,"about_ca_system_score_codex":0.0002750076,"about_ca_system_score_gemma":0.00032902564,"threshold_uncertainty_score":0.007609248},"labels":[],"label_agreement":null},{"id":"W4402759024","doi":"10.1172/jci181095","title":"Stimulation of an entorhinal-hippocampal extinction circuit facilitates fear extinction in a post-traumatic stress disorder model","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Memory and Neural Mechanisms","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; Hospital for Sick Children; University of Toronto","funders":"Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China; Shanghai Municipal Health Commission","keywords":"Extinction (optical mineralogy); Neuroscience; Stimulation; Hippocampal formation; Traumatic stress; Psychology; Entorhinal cortex; Medicine; Clinical psychology; Physics; Optics","score_opus":0.21751263165042653,"score_gpt":0.4092692012938647,"score_spread":0.19175656964343815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402759024","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962296,0.00031991932,0.0020723944,0.000117250915,0.000051585805,0.00003786832,0.00008608755,0.00012288237,0.0009624212],"genre_scores_gemma":[0.9967457,0.00034895667,0.0011032968,0.00005367816,0.000011977925,0.000059695238,0.000071613176,0.000009890505,0.0015951472],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999238,0.000008713137,0.0000050969575,0.000016222679,0.000017284869,0.000028838418],"domain_scores_gemma":[0.99996006,0.0000033682215,0.000010028301,0.000006007018,0.0000041809403,0.000016415614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000085285,0.000395287,0.0002685584,0.00020495101,0.00012592608,0.00014610533,0.00024742648,0.00020300863,0.001154368],"category_scores_gemma":[0.000090442125,0.00011530353,0.00021835195,0.00007897166,0.00032441298,0.00018740783,0.00017317619,0.00094342686,0.00018101999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060510327,0.00030940125,0.0001350692,0.00005401534,0.000010686968,0.0000727618,0.00003183919,0.00014326359,0.99387723,0.00016399207,0.00010734245,0.0044893394],"study_design_scores_gemma":[0.00019050081,0.006052597,0.0058298614,0.000022626815,0.00006663977,0.00033176312,0.0000822951,0.003230366,0.9821259,0.00029409825,0.0017615623,0.000011959788],"about_ca_topic_score_codex":0.0005271703,"about_ca_topic_score_gemma":0.0009987035,"teacher_disagreement_score":0.001154368,"about_ca_system_score_codex":0.00018809956,"about_ca_system_score_gemma":0.0002138692,"threshold_uncertainty_score":0.0038617253},"labels":[],"label_agreement":null},{"id":"W4402968553","doi":"10.1172/jci178604","title":"Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Movember Foundation; National Cancer Institute; Stand Up To Cancer; Prostate Cancer Foundation","keywords":"Prostate cancer; Androgen receptor; Transcriptome; Cancer research; Medicine; Receptor; Castration; Biology; Bioinformatics; Oncology; Internal medicine; Cancer; Genetics; Gene; Hormone; Gene expression","score_opus":0.08180279273391518,"score_gpt":0.39974987060513373,"score_spread":0.31794707787121856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402968553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99382764,0.00092506455,0.0005866544,0.00008399714,0.000005724293,0.0000120909335,0.0039762463,0.000031326017,0.0005512651],"genre_scores_gemma":[0.9950683,0.00035571572,0.0005945448,0.00007062296,0.000009544826,0.000027056583,0.00346128,0.000011958474,0.00040104074],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99989164,0.000010830448,0.0000056483873,0.00004331886,0.000023438164,0.000025081987],"domain_scores_gemma":[0.9998523,0.000024928053,0.00006960058,0.000009975058,0.000017125301,0.000025996951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110636916,0.00013472362,0.00019381617,0.00054729695,0.00018283392,0.00031834535,0.00011011519,0.00017030867,0.0014699467],"category_scores_gemma":[0.00024090688,0.00009647741,0.00018501922,0.0005749985,0.00014858012,0.00009048155,0.00018101481,0.00020890699,0.00014608291],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010982428,0.00007650708,0.33518448,0.00024113522,0.00022758628,0.00070417504,0.00027297542,0.0011547984,0.63811636,0.00029877658,0.0012714898,0.021353489],"study_design_scores_gemma":[0.000011761059,0.00013337814,0.9882885,0.000010010137,0.000070208174,0.00092679344,0.00015883337,0.001031973,0.0073868083,0.0001524194,0.0018212212,0.000007975672],"about_ca_topic_score_codex":0.0011179529,"about_ca_topic_score_gemma":0.00239868,"teacher_disagreement_score":0.0014699467,"about_ca_system_score_codex":0.00017500846,"about_ca_system_score_gemma":0.00016124571,"threshold_uncertainty_score":0.004917443},"labels":[],"label_agreement":null},{"id":"W4403382149","doi":"10.1172/jci172887","title":"Cannabis use disorder: from neurobiology to treatment","year":2024,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Brain Institute; Centre for Addiction and Mental Health","funders":"University of Toronto; Indivior","keywords":"Cannabis; Neuroscience; Psychiatry; Medicine; Psychology; Bioinformatics; Biology","score_opus":0.21595075491610885,"score_gpt":0.48844354856617617,"score_spread":0.2724927936500673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403382149","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008259635,0.9989673,0.000031816195,0.0003061916,0.0000875036,0.000003678001,0.00000777927,0.000002441447,0.00051060756],"genre_scores_gemma":[0.00063571485,0.99886036,0.000060371047,0.00011842486,0.0001001338,0.000005304873,0.000009736482,6.1125047e-7,0.00020928292],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997936,0.000047466885,0.00003452914,0.0000314737,0.000070516326,0.000022414992],"domain_scores_gemma":[0.9997222,0.00015911712,0.00003666257,0.0000077864925,0.000052046737,0.000022066115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052127667,0.00073862844,0.0014223617,0.0021710931,0.000385207,0.0011852059,0.0007714236,0.0011829654,0.00431028],"category_scores_gemma":[0.0008894336,0.0002603882,0.00065727456,0.0014701042,0.0006179172,0.00087438023,0.0007342289,0.0018123076,0.0011439262],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000860587,0.00008570063,0.0001734522,0.03352143,0.00012864404,0.0002197192,0.00008961038,0.00024742194,0.0006364808,0.004348991,0.017681582,0.9427809],"study_design_scores_gemma":[0.000076827186,0.00017582045,0.0028076246,0.045433752,0.00037981,0.0027000494,0.00021815239,0.00022429175,0.00054940773,0.007442647,0.9399466,0.000044954668],"about_ca_topic_score_codex":0.0028868017,"about_ca_topic_score_gemma":0.0058220318,"teacher_disagreement_score":0.00431028,"about_ca_system_score_codex":0.0009425612,"about_ca_system_score_gemma":0.0017941232,"threshold_uncertainty_score":0.014419317},"labels":[],"label_agreement":null},{"id":"W4403638688","doi":"10.1172/jci183984","title":"Attenuated kidney oxidative metabolism in young adults with type 1 diabetes","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Population and Public Health; University of Toronto; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Michigan; Centers for Disease Control and Prevention; Boettcher Foundation; American Heart Association","keywords":"Oxidative metabolism; Oxidative phosphorylation; Diabetes mellitus; Metabolism; Medicine; Type 2 diabetes; Kidney; Endocrinology; Internal medicine; Biology; Physiology; Biochemistry","score_opus":0.017754214758441342,"score_gpt":0.30440841718025924,"score_spread":0.2866542024218179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403638688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99215394,0.0033224623,0.0004582141,0.00021936785,0.0000550301,0.00007365344,0.0024419145,0.000021396345,0.001254033],"genre_scores_gemma":[0.9927545,0.0020906471,0.0014874248,0.00032048364,0.000068346606,0.000099474826,0.0025264043,0.0000085011325,0.00064412097],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99988496,0.000024865612,0.000010166157,0.000039592378,0.000018566347,0.00002184477],"domain_scores_gemma":[0.9996902,0.00005385491,0.00011165927,0.000014306677,0.000050239963,0.00007969631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049375114,0.0002682321,0.0004895045,0.00030519816,0.00041933198,0.0005624898,0.00017570354,0.00038028692,0.002629487],"category_scores_gemma":[0.0007600851,0.00017032296,0.0004035456,0.00047629495,0.0001280762,0.00027690825,0.00035915905,0.0003726968,0.00026739994],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004050208,0.00032121065,0.9538776,0.00044817154,0.00024620927,0.0004273482,0.00021760426,0.00019546384,0.0029819177,0.000121217396,0.0017258609,0.035387084],"study_design_scores_gemma":[0.00013250533,0.0009039384,0.99507385,0.00014684288,0.00021024304,0.00066062005,0.0002445234,0.00042310113,0.00042281573,0.00022697686,0.0015430253,0.000011533719],"about_ca_topic_score_codex":0.003250501,"about_ca_topic_score_gemma":0.0077233966,"teacher_disagreement_score":0.003250501,"about_ca_system_score_codex":0.00027002077,"about_ca_system_score_gemma":0.0003358201,"threshold_uncertainty_score":0.008796513},"labels":[],"label_agreement":null},{"id":"W4403852334","doi":"10.1172/jci179501","title":"Immunological and molecular features of the tumor microenvironment of long-term survivors of ovarian cancer","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Women's Health Research Institute; BC Cancer Agency; Foothills Medical Centre; Vancouver General Hospital; University of Calgary; University of Victoria; University of British Columbia","funders":"Medical Research and Materiel Command; Congressionally Directed Medical Research Programs; National Cancer Institute; Instituto de Salud Carlos III; Cancer Council Tasmania; Cancer Council Victoria; National Center for Advancing Translational Sciences; Medical Research Council; Foundation Medicine; National Institutes of Health; Peter MacCallum Foundation; Canadian Institutes of Health Research; Cancer Institute NSW; Terry Fox Research Institute; Cancer Council Western Australia; Cancer Australia; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; Cancer Council NSW; Marshfield Clinic Research Foundation; Ovarian Cancer Australia; Genome British Columbia; Fred C. and Katherine B. Andersen Foundation; Mayo Foundation for Medical Education and Research; Deutsche Forschungsgemeinschaft; VGH and UBC Hospital Foundation; Friedrich-Alexander-Universität Erlangen-Nürnberg; Cancer Council South Australia; Deutsches Krebsforschungszentrum; Cancer Council Queensland; Ministerio de Economía y Competitividad; University of Pittsburgh; Victorian Cancer Agency; National Health and Medical Research Council; AstraZeneca; Pfizer; National Center for Research Resources; BC Cancer Foundation; Oak Foundation; Cancer Research UK; Minnesota Ovarian Cancer Alliance; U.S. Department of Defense","keywords":"Term (time); Cancer; Ovarian cancer; Tumor microenvironment; Cancer research; Medicine; Oncology; Biology; Immunology; Bioinformatics; Internal medicine","score_opus":0.03837565036358295,"score_gpt":0.35037581692255637,"score_spread":0.31200016655897345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403852334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9996257,0.00012812551,0.000030147308,0.0000072346365,0.0000012640078,0.0000016227843,0.00008457192,0.0000011648928,0.000120154386],"genre_scores_gemma":[0.99969184,0.000051937364,0.000022955748,0.000006440742,0.0000046061964,0.0000029540724,0.00014293546,7.2702267e-7,0.00007553693],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9999211,0.000016542392,0.0000061194423,0.000016409229,0.000011775269,0.000028062454],"domain_scores_gemma":[0.99967885,0.000040958235,0.00014461543,0.000019488596,0.000029931527,0.0000861044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015520923,0.000108560365,0.00011304493,0.00040715313,0.00023820421,0.00029851744,0.000105590654,0.00016455157,0.00088442385],"category_scores_gemma":[0.00046391666,0.00007626063,0.00009590238,0.0002878944,0.00017819073,0.0001700043,0.00028202092,0.0001866307,0.00011179883],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015660925,0.000011390127,0.9946408,0.0000062181934,0.000013784526,0.0001154935,0.000057863923,0.000027244369,0.003572435,0.000012237864,0.000049254482,0.001336659],"study_design_scores_gemma":[0.00000128861,0.000052918655,0.9989281,0.0000012853709,0.000006065692,0.00048257664,0.00012889554,0.000044987137,0.00023070401,0.000013202728,0.00010886821,0.0000011534347],"about_ca_topic_score_codex":0.0009442631,"about_ca_topic_score_gemma":0.0013758477,"teacher_disagreement_score":0.0009442631,"about_ca_system_score_codex":0.00014460926,"about_ca_system_score_gemma":0.00010451966,"threshold_uncertainty_score":0.0029586554},"labels":[],"label_agreement":null},{"id":"W4403925108","doi":"10.1172/jci186744","title":"Hidradenitis suppurativa: key insights into treatment success and failure","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hidradenitis Suppurativa and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"Galderma; Celgene; Sanofi; Pfizer; Eli Lilly and Company","keywords":"Hidradenitis suppurativa; Key (lock); Medicine; Intensive care medicine; Computer science; Pathology; Disease; Computer security","score_opus":0.06206884094687373,"score_gpt":0.3902539223013143,"score_spread":0.3281850813544406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403925108","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07630529,0.8475666,0.002654717,0.047375597,0.0011159624,0.00012095837,0.00024784205,0.000041523846,0.024571573],"genre_scores_gemma":[0.7417503,0.242495,0.0024351606,0.005770482,0.005592426,0.00016683666,0.00014428185,0.000033301432,0.0016122358],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99569005,0.0019681775,0.0005185514,0.00033830246,0.0009967249,0.000488263],"domain_scores_gemma":[0.97846186,0.01585053,0.003038261,0.00043265312,0.0011708481,0.0010458255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0075861677,0.00053245155,0.0021391679,0.0018869702,0.00063187454,0.0053979224,0.0007994575,0.0015218643,0.0026386932],"category_scores_gemma":[0.022103185,0.00027875556,0.00046711534,0.0016164151,0.004460816,0.0048320782,0.0019567162,0.0027049966,0.00038039713],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030386029,0.0008093087,0.08898419,0.0058413106,0.0005128112,0.001445634,0.004271583,0.0005505078,0.002477982,0.08534128,0.011933816,0.794793],"study_design_scores_gemma":[0.0010220199,0.0058571077,0.40851632,0.02322519,0.001692912,0.015108844,0.023825202,0.0052838814,0.0040830574,0.28112677,0.22975373,0.000504985],"about_ca_topic_score_codex":0.0007925965,"about_ca_topic_score_gemma":0.001148726,"teacher_disagreement_score":0.0075861677,"about_ca_system_score_codex":0.002208097,"about_ca_system_score_gemma":0.0032891755,"threshold_uncertainty_score":0.040119946},"labels":[],"label_agreement":null},{"id":"W4404350023","doi":"10.1172/jci170669","title":"Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Ottawa Fertility Centre; Centre Hospitalier de l’Université de Montréal; McGill University; Concordia University; McGill University Health Centre","funders":"Faculty of Medicine and Health, University of Sydney; Hunter Medical Research Institute; Strong; Qingdao Agricultural University; Canadian Institutes of Health Research; Mitacs; McGill University Health Centre; Baystate Health; McGill University","keywords":"Meiosis; Disorders of sex development; Biology; Computational biology; Bioinformatics; Genetics; Medicine; Gene","score_opus":0.07156748703026831,"score_gpt":0.37835556330152725,"score_spread":0.3067880762712589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404350023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987588,0.00041462187,0.00028477394,0.000024686375,0.0000026306354,0.0000033749047,0.000050578914,0.00001537928,0.00044516768],"genre_scores_gemma":[0.99941576,0.00017523719,0.00021288336,0.000009711165,0.0000047365784,0.0000014306507,0.000031567564,0.0000033904234,0.00014525221],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99990284,0.000018113727,0.000011726061,0.000027856418,0.000020835596,0.00001858294],"domain_scores_gemma":[0.9997608,0.00006179486,0.00010480829,0.000019019684,0.000008998155,0.000044546323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012528553,0.00035679014,0.0001857482,0.00056029356,0.00023761057,0.00020452542,0.00012396633,0.00019809407,0.0015327148],"category_scores_gemma":[0.0007421701,0.00014272415,0.00014095753,0.00025921853,0.0003267213,0.00015812561,0.0002586199,0.00018408816,0.00013662783],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007482595,0.000066185225,0.5069186,0.00014287423,0.00010509758,0.0314681,0.0008389444,0.00066601764,0.43106255,0.0010847693,0.00027999253,0.026618663],"study_design_scores_gemma":[0.000060189992,0.00040490986,0.80444944,0.000029728964,0.00015501551,0.12148769,0.00049724727,0.0008928996,0.06691743,0.0006894867,0.0043919934,0.000024004408],"about_ca_topic_score_codex":0.00045042374,"about_ca_topic_score_gemma":0.0005295494,"teacher_disagreement_score":0.0015327148,"about_ca_system_score_codex":0.0001233894,"about_ca_system_score_gemma":0.00012378041,"threshold_uncertainty_score":0.00512743},"labels":[],"label_agreement":null},{"id":"W4404745306","doi":"10.1172/jci183873","title":"Neuropilin-1 inhibition suppresses nerve growth factor signaling and nociception in pain models","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; York University; University of Cincinnati; National Institute on Drug Abuse; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Nociceptor; Nerve growth factor; Tropomyosin receptor kinase A; Neuropilin 1; Low-affinity nerve growth factor receptor; Cell biology; Signal transduction; Nociception; Chemistry; Endosome; Receptor; Endocrinology; Internal medicine; Biology; Medicine","score_opus":0.1246719968110394,"score_gpt":0.3737778605214032,"score_spread":0.2491058637103638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404745306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98753965,0.007172293,0.0021251733,0.00018379648,0.00009790902,0.00007381601,0.0005141747,0.0002463182,0.002046882],"genre_scores_gemma":[0.98960763,0.0043414542,0.0017361387,0.00011900526,0.000025712749,0.0001270332,0.0010530249,0.000025118214,0.00296485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982136,0.000034251585,0.000017168957,0.000026840415,0.000047636226,0.000052680643],"domain_scores_gemma":[0.9999217,0.0000066363714,0.000024445124,0.0000058284613,0.000009160743,0.000032210468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018191178,0.0004966607,0.0004316661,0.00034424715,0.00013605191,0.00020696326,0.00027262545,0.00025487784,0.0010986866],"category_scores_gemma":[0.00008931526,0.0001442615,0.00026108077,0.00017771886,0.00019468408,0.00018381981,0.00014468208,0.0009012114,0.00026365326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046729657,0.0001779078,0.00017452083,0.00016859513,0.000026562959,0.000068765155,0.000009912948,0.00010537753,0.994351,0.00009740086,0.0002563661,0.0040962286],"study_design_scores_gemma":[0.00016556603,0.0029117123,0.01234582,0.00002415598,0.00012031316,0.00076764403,0.000037274764,0.002353602,0.97462887,0.00008701998,0.0065434193,0.0000146316],"about_ca_topic_score_codex":0.0005814828,"about_ca_topic_score_gemma":0.0010510209,"teacher_disagreement_score":0.0010986866,"about_ca_system_score_codex":0.0002640102,"about_ca_system_score_gemma":0.00018023944,"threshold_uncertainty_score":0.0036755204},"labels":[],"label_agreement":null},{"id":"W4405235989","doi":"10.1172/jci177429","title":"C2230, a preferential use- and state-dependent CaV2.2 channel blocker, mitigates pain behaviors across multiple pain models","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Institute on Drug Abuse; Texas Biomedical Research Institute; Education Department of Hunan Province; York University; University of Texas Health Science Center at San Antonio; University of Florida","keywords":"Neuropathic pain; Excitatory postsynaptic potential; Medicine; Gabapentin; Calcium channel blocker; Pharmacology; Nociception; Voltage-dependent calcium channel; Neuroscience; Anesthesia; Analgesic; Chronic pain; Calcium channel; Nerve injury; Inhibitory postsynaptic potential; Internal medicine; Calcium; Psychology; Receptor","score_opus":0.12391078188786772,"score_gpt":0.3860840147306143,"score_spread":0.26217323284274663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405235989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898621,0.0032711318,0.0034511967,0.00022738712,0.00011923878,0.00007356555,0.00026688373,0.000255173,0.002473422],"genre_scores_gemma":[0.9916802,0.0028374132,0.0018171666,0.0002666708,0.00003477043,0.00008065209,0.00032551648,0.000040389605,0.0029172723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998486,0.000015603058,0.000014695593,0.000031774613,0.0000450398,0.000044309145],"domain_scores_gemma":[0.99992776,0.0000074253435,0.000026359949,0.0000074584873,0.000011808026,0.000019213645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013073925,0.00041291106,0.00038582648,0.00021701738,0.00016817181,0.00022549824,0.00031817815,0.0003243038,0.001319639],"category_scores_gemma":[0.00012872425,0.00014906915,0.00035718273,0.000118192984,0.00025073122,0.00028421564,0.00015116167,0.0010671035,0.00021538229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048739783,0.00014485058,0.000108699336,0.00010754068,0.000019223404,0.000043779793,0.000014221488,0.000077376695,0.99480337,0.00010808108,0.00021001839,0.0038754416],"study_design_scores_gemma":[0.00013267876,0.0036098051,0.0028864727,0.00001570968,0.00009932234,0.00043721817,0.000028711858,0.0013408324,0.98726463,0.00007297119,0.004094145,0.00001753961],"about_ca_topic_score_codex":0.0007063305,"about_ca_topic_score_gemma":0.0016974653,"teacher_disagreement_score":0.001319639,"about_ca_system_score_codex":0.00019094549,"about_ca_system_score_gemma":0.00026202164,"threshold_uncertainty_score":0.0044146776},"labels":[],"label_agreement":null},{"id":"W4405318361","doi":"10.1172/jci178722","title":"Estimation of prevalence of autoimmune diseases in the United States using electronic health record data","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Population and Public Health","funders":"National Center for Advancing Translational Sciences; University of Southern California; National Institute of Environmental Health Sciences; National Institutes of Health; National Heart, Lung, and Blood Institute; Massachusetts General Hospital","keywords":"Estimation; Electronic health record; Medicine; Health records; Environmental health; Statistics; Data science; Computer science; Mathematics; Political science; Health care; Law","score_opus":0.06678148431522449,"score_gpt":0.40076999035724853,"score_spread":0.333988506042024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405318361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80664104,0.005711225,0.03817472,0.0014951427,0.000100886,0.00075502094,0.14163536,0.00058978423,0.004896814],"genre_scores_gemma":[0.89939207,0.0029711935,0.03418591,0.000370019,0.00015403262,0.0009216687,0.061513226,0.00003673097,0.00045515678],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99050057,0.0041076853,0.0022986105,0.0012827376,0.0015726056,0.00023783471],"domain_scores_gemma":[0.96801794,0.013148666,0.012509126,0.0029406473,0.0029999262,0.00038368415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008776113,0.00051821134,0.00068513316,0.008565103,0.00027706643,0.0011163184,0.0009248824,0.00056162645,0.0019413447],"category_scores_gemma":[0.03203134,0.00044777084,0.0012720629,0.009096322,0.0002779764,0.0012314515,0.001094618,0.0005958544,0.00041610378],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006792308,0.00004782683,0.98148066,0.00028597857,0.00076020526,0.000034708493,0.00008142868,0.0011427584,0.00010813297,0.00028316485,0.002202248,0.013505007],"study_design_scores_gemma":[0.000058340916,0.000098944685,0.9876408,0.00022590163,0.00050717156,0.00028562004,0.00020901294,0.0062715397,0.0003425565,0.0008064863,0.0035226494,0.00003102744],"about_ca_topic_score_codex":0.016630746,"about_ca_topic_score_gemma":0.012189682,"teacher_disagreement_score":0.016630746,"about_ca_system_score_codex":0.0007300743,"about_ca_system_score_gemma":0.00096262654,"threshold_uncertainty_score":0.046413064},"labels":[],"label_agreement":null},{"id":"W4405407735","doi":"10.1172/jci187783","title":"The paradox of eGFR trends and kidney failure incidence in patients without monogenic kidney disorders. Reply.","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Incidence (geometry); Kidney; Medicine; Internal medicine; Bioinformatics; Intensive care medicine; Biology; Mathematics","score_opus":0.02329240711761159,"score_gpt":0.34449302441156043,"score_spread":0.32120061729394883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405407735","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0023985542,0.0107846875,0.00024452584,0.9545319,0.03051414,0.000023810075,0.00092967675,0.00006113607,0.0005115376],"genre_scores_gemma":[0.02249269,0.012248515,0.00083192525,0.8517165,0.10914351,0.0001382625,0.0006821647,0.00006810424,0.0026782816],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982357,0.0005403857,0.0003449308,0.00035175675,0.0003595144,0.00016770409],"domain_scores_gemma":[0.97552717,0.014656229,0.0021554101,0.00097507535,0.005398929,0.0012871412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007890928,0.00076834054,0.0012860383,0.0011858592,0.00076679315,0.0014647124,0.0022328957,0.009520017,0.0062731327],"category_scores_gemma":[0.04439177,0.00058291806,0.0012724833,0.001298455,0.001136451,0.004372436,0.0012738258,0.016411066,0.0033656335],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044253696,0.000042402895,0.013356395,0.00050774723,0.00017533993,0.00061560905,0.00033582855,0.000113146336,0.00019858936,0.0011182392,0.9632241,0.019870048],"study_design_scores_gemma":[0.00093817717,0.0005395735,0.14139345,0.0030262973,0.00086518534,0.0057944786,0.004840118,0.0024695904,0.0013996767,0.018988524,0.8189751,0.0007698144],"about_ca_topic_score_codex":0.010451269,"about_ca_topic_score_gemma":0.008029154,"teacher_disagreement_score":0.010451269,"about_ca_system_score_codex":0.0009978313,"about_ca_system_score_gemma":0.0015175489,"threshold_uncertainty_score":0.041731715},"labels":[],"label_agreement":null},{"id":"W4405407747","doi":"10.1172/jci184790","title":"Immune-molecular interactions in high-grade serous ovarian cancer distinguish long-term survivors","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Ovarian Cancer Canada","keywords":"Serous ovarian cancer; Ovarian cancer; Term (time); Immune system; Serous fluid; Medicine; Cancer; Biology; Oncology; Bioinformatics; Cancer research; Internal medicine; Immunology; Physics","score_opus":0.07930643492989356,"score_gpt":0.4239870536736384,"score_spread":0.3446806187437449,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405407747","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967445,0.0019178855,0.000095028954,0.00023803946,0.000029151202,0.000006438838,0.00010484544,0.0000055206715,0.0008585474],"genre_scores_gemma":[0.99877244,0.0005795395,0.000089557034,0.00010481887,0.000059400274,0.000004057356,0.00014123981,0.0000017658209,0.00024716335],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9999076,0.000023654584,0.000009924775,0.0000126531295,0.000018177117,0.000028004944],"domain_scores_gemma":[0.99962854,0.00009250651,0.00014207963,0.00002000891,0.000045849498,0.00007095785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026724956,0.00010859691,0.00018787911,0.0005792811,0.0002504815,0.00051171886,0.00013309612,0.0002728267,0.00091310375],"category_scores_gemma":[0.0008143593,0.00007861581,0.00014413803,0.000511439,0.00018103413,0.00036972263,0.00030750493,0.00035588196,0.00014755568],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003042287,0.0000307421,0.9827319,0.00002469686,0.000027357692,0.0002913985,0.0001629881,0.00004168042,0.0023159601,0.000045273715,0.00049240066,0.013531467],"study_design_scores_gemma":[0.000004602654,0.000096780794,0.99626297,0.000009593405,0.000034497956,0.00088699063,0.0004927505,0.00011133283,0.00044597074,0.000083309875,0.0015676097,0.000003698957],"about_ca_topic_score_codex":0.00064018613,"about_ca_topic_score_gemma":0.0016746926,"teacher_disagreement_score":0.00091310375,"about_ca_system_score_codex":0.0001672046,"about_ca_system_score_gemma":0.00013402186,"threshold_uncertainty_score":0.0030546784},"labels":[],"label_agreement":null},{"id":"W4405463732","doi":"10.1172/jci183353","title":"Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian VIGOUR Centre; University of Alberta","funders":"Lawrence Berkeley National Laboratory; National Institute of Child Health and Human Development; National Human Genome Research Institute; NHLBI Division of Intramural Research; British Heart Foundation; National Heart, Lung, and Blood Institute; U.S. Department of Energy; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Enhancer; Biology; Titin; Cell biology; Induced pluripotent stem cell; Sarcomere; Molecular biology; Haploinsufficiency; Gene expression; Genetics; Gene; Embryonic stem cell; Myocyte; Phenotype","score_opus":0.043011381121353366,"score_gpt":0.38690827710074777,"score_spread":0.3438968959793944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405463732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99591225,0.00042398454,0.0029488378,0.00003225892,0.0000066926004,0.00001040793,0.00010747119,0.000046558933,0.00051152764],"genre_scores_gemma":[0.996523,0.00023671649,0.0021393101,0.000018213428,0.000005226921,0.000011684953,0.00025557054,0.000014438972,0.00079580344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999101,0.000015255437,0.000009487088,0.00002450686,0.00002685053,0.000013745726],"domain_scores_gemma":[0.9998919,0.000028723918,0.000035429715,0.00001104895,0.0000065455506,0.000026386366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017523489,0.00020182265,0.00010628922,0.00011868607,0.0000940498,0.00014872215,0.00011841589,0.00013914921,0.0006380536],"category_scores_gemma":[0.0001487586,0.00009994842,0.00007758204,0.00004949547,0.00020783355,0.00007534795,0.0001638275,0.00019139133,0.00021039402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026370277,0.0000068155928,0.0002916763,0.000006693916,0.0000010334585,0.000021683201,0.000005668908,0.000026979416,0.99891436,0.000050753217,0.0000052685054,0.00064280076],"study_design_scores_gemma":[0.000029513729,0.00032236075,0.045737848,0.000012949786,0.000018175235,0.0007076796,0.000037411173,0.0021043306,0.9488152,0.00016604157,0.0020408393,0.0000075667444],"about_ca_topic_score_codex":0.00015860915,"about_ca_topic_score_gemma":0.00043162532,"teacher_disagreement_score":0.0006380536,"about_ca_system_score_codex":0.00010800022,"about_ca_system_score_gemma":0.00013467186,"threshold_uncertainty_score":0.0021345615},"labels":[],"label_agreement":null},{"id":"W4405614611","doi":"10.1172/jci164997","title":"Metalloproteinase inhibitors regulate biliary progenitor cells through sDLK1 in organoid models of liver injury","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Liver physiology and pathology","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Tech University; University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research; Ontario Institute for Regenerative Medicine; Peking University Health Science Center; Peking University","keywords":"Cholangiocyte; Progenitor cell; Organoid; Notch signaling pathway; Cell biology; TIMP1; Stem cell; Cancer research; Liver injury; Mesenchymal stem cell; Cellular differentiation; Biology; Stromal cell; Immunology; Pathology; Medicine; Endocrinology; Signal transduction; Biochemistry","score_opus":0.08563399891996966,"score_gpt":0.36996799406219,"score_spread":0.28433399514222035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405614611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9834405,0.0029623797,0.008006877,0.00031130575,0.00007233117,0.00006124159,0.0021181868,0.00045701067,0.0025701788],"genre_scores_gemma":[0.9871132,0.0013774344,0.0032854555,0.00008740817,0.00000766912,0.00010667547,0.0016334187,0.00007122028,0.0063176556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999731,0.00004239623,0.0000306588,0.000056853693,0.000077620985,0.00006155973],"domain_scores_gemma":[0.999843,0.000015474876,0.000049447826,0.000019764262,0.000014674041,0.000057589652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022677337,0.00034138438,0.0003105051,0.00050277455,0.00024350155,0.0005379156,0.00020646813,0.0002585637,0.001880012],"category_scores_gemma":[0.00011430426,0.00018050912,0.00032540885,0.00023700307,0.00037879404,0.00030714192,0.00030502275,0.0010890119,0.00066750246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022460555,0.00002468658,0.00020392473,0.000046812234,0.0000050949466,0.000041315794,0.000027595239,0.00006632853,0.9982052,0.0000892222,0.00006885641,0.0009963742],"study_design_scores_gemma":[0.000014343972,0.00018797569,0.0019515672,0.0000047423714,0.000012896391,0.00010003031,0.00005611866,0.0005363436,0.9950418,0.00004608348,0.0020446125,0.0000033850886],"about_ca_topic_score_codex":0.00081496325,"about_ca_topic_score_gemma":0.0020587035,"teacher_disagreement_score":0.001880012,"about_ca_system_score_codex":0.0005229763,"about_ca_system_score_gemma":0.0004020059,"threshold_uncertainty_score":0.0062893033},"labels":[],"label_agreement":null},{"id":"W4405967896","doi":"10.1172/jci184656","title":"APP lysine 612 lactylation ameliorates amyloid pathology and memory decline in Alzheimer’s disease","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Centre Scientifique et Technique du Bâtiment; Natural Science Foundation of Chongqing; Chongqing Medical University; National Natural Science Foundation of China","keywords":"Disease; Amyloid (mycology); Alzheimer's disease; Pathology; Medicine; Lysine; Biology; Biochemistry; Amino acid","score_opus":0.08893875094829513,"score_gpt":0.42558902195050197,"score_spread":0.33665027100220685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405967896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911389,0.0055084955,0.00090483774,0.00024873967,0.0001520125,0.00006402752,0.00020006722,0.00021101201,0.0015719301],"genre_scores_gemma":[0.9913362,0.0040592654,0.0008636347,0.0002423904,0.00005813487,0.00007867365,0.00038111198,0.000027554463,0.0029530053],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988616,0.000018348208,0.00001755555,0.000016749067,0.000026038275,0.000035231864],"domain_scores_gemma":[0.99992526,0.000003618994,0.000017198501,0.000008623522,0.00001124728,0.000034130542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024330706,0.00070597616,0.001016904,0.00038905587,0.00025748718,0.00036414198,0.00035904266,0.00051883585,0.0012701626],"category_scores_gemma":[0.0001328547,0.0002112316,0.00034364854,0.00020846588,0.00029256032,0.0004518823,0.00026280375,0.0009671444,0.00034032032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009981353,0.0031301433,0.0005775705,0.00037458353,0.000109761524,0.00030667929,0.00008158954,0.00018935144,0.95074356,0.00024664027,0.0008542585,0.033404607],"study_design_scores_gemma":[0.0042089536,0.049475547,0.03635314,0.00014927244,0.0009130862,0.0017518025,0.00033491434,0.0036430773,0.87776035,0.0012548844,0.024078405,0.00007658304],"about_ca_topic_score_codex":0.0007164655,"about_ca_topic_score_gemma":0.00088995916,"teacher_disagreement_score":0.0012701626,"about_ca_system_score_codex":0.00015713272,"about_ca_system_score_gemma":0.00036964513,"threshold_uncertainty_score":0.0042491555},"labels":[],"label_agreement":null},{"id":"W4405967898","doi":"10.1172/jci181630","title":"Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institute of Biomedical Imaging and Bioengineering; American Heart Association","keywords":"Dilated cardiomyopathy; Fibrosis; Cardiac fibrosis; Cardiomyopathy; Medicine; BAG3; Fibroblast; Myocardial fibrosis; Cancer research; Heart failure; Cardiology; Internal medicine; Biology; Autophagy; Cell culture; Genetics","score_opus":0.03633411086615584,"score_gpt":0.3404545668808731,"score_spread":0.30412045601471727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405967898","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885251,0.0049731573,0.0027737527,0.00033226438,0.0000728896,0.000021640544,0.0004472799,0.000108616274,0.0027452807],"genre_scores_gemma":[0.99557894,0.001092361,0.00071530853,0.00013643916,0.000011282885,0.000020429983,0.00027658787,0.0000144476235,0.0021540576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998803,0.000028292783,0.0000092465625,0.000017558847,0.00003673081,0.000027862936],"domain_scores_gemma":[0.9999094,0.000008799624,0.000030442014,0.000005737411,0.000010741336,0.00003496357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016045598,0.00029551837,0.00014830609,0.00022462488,0.0002291586,0.00027814496,0.0001462828,0.00029860088,0.0015352805],"category_scores_gemma":[0.000086385975,0.000103820355,0.00018621174,0.000120656085,0.00022904851,0.00015807104,0.00024529977,0.00046944973,0.00041082408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031571017,0.00003329037,0.0013371696,0.000048494792,0.000008014902,0.0002091349,0.000023780687,0.00006292725,0.9954151,0.00017114912,0.00012811791,0.002246937],"study_design_scores_gemma":[0.00016490147,0.00041667247,0.12806179,0.00004923027,0.000086179214,0.0021163884,0.0003461809,0.0031602317,0.8534198,0.0006191988,0.011532483,0.000027007418],"about_ca_topic_score_codex":0.00049082976,"about_ca_topic_score_gemma":0.0011278973,"teacher_disagreement_score":0.0015352805,"about_ca_system_score_codex":0.0002389248,"about_ca_system_score_gemma":0.00019328466,"threshold_uncertainty_score":0.0051359534},"labels":[],"label_agreement":null},{"id":"W4406387153","doi":"10.1172/jci187567","title":"A new twist on superantigen-activated autoimmune disease","year":2025,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Superantigen; Autoimmune disease; Immunology; Medicine; Twist; Computational biology; Biology; Immune system; T cell; Antibody","score_opus":0.03143174601528613,"score_gpt":0.32818715905377294,"score_spread":0.2967554130384868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406387153","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013386188,0.02278859,0.0005826485,0.869538,0.101831,0.000012145521,0.000039181406,0.000096045136,0.0037737787],"genre_scores_gemma":[0.013911342,0.026078988,0.0007666608,0.5366482,0.41618928,0.000028123324,0.000037607766,0.000038758364,0.006301014],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982368,0.00047880367,0.0002498591,0.00024982909,0.0005714555,0.00021322597],"domain_scores_gemma":[0.9947404,0.003076357,0.0002445543,0.00033788654,0.0008579712,0.00074292335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002896058,0.0007545437,0.0011400682,0.00065573415,0.0014788955,0.0032966468,0.0011837735,0.015030108,0.0033685828],"category_scores_gemma":[0.006214292,0.0003998747,0.00066992996,0.00035841495,0.0037766367,0.0048300885,0.0013797395,0.02972704,0.0019689775],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022740712,0.00012919989,0.0008046804,0.00040272274,0.00004327564,0.0068293186,0.0002742925,0.00008801547,0.002379746,0.018500645,0.91847944,0.05184127],"study_design_scores_gemma":[0.00013729965,0.00014171828,0.00061373727,0.00024673078,0.000027424703,0.0061005307,0.00026387654,0.0003058086,0.0006077034,0.022173708,0.9693443,0.000037036607],"about_ca_topic_score_codex":0.00036871617,"about_ca_topic_score_gemma":0.00094546995,"teacher_disagreement_score":0.015030108,"about_ca_system_score_codex":0.0016889095,"about_ca_system_score_gemma":0.0012312721,"threshold_uncertainty_score":0.0153160095},"labels":[],"label_agreement":null},{"id":"W4406664644","doi":"10.1172/jci188016","title":"Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Faculty of Medicine and Health, University of Sydney; National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; St. Giles Foundation; Universiteit Stellenbosch; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; CHIST-ERA; National Center for Advancing Translational Sciences; Agence Nationale de la Recherche; South African Medical Research Council; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada; McGill University Health Centre; McGill University; Institut des maladies génétiques Imagine","keywords":"Granulysin; CTL*; Cytotoxic T cell; Perforin; Mycobacterium tuberculosis; Immunology; Biology; Granzyme; Bronchoalveolar lavage; T cell; Ex vivo; Virology; Microbiology; CD8; Medicine; Immune system; Tuberculosis; In vitro; Lung; Pathology","score_opus":0.02679595442364356,"score_gpt":0.2988540074960211,"score_spread":0.2720580530723775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406664644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99903536,0.00033563477,0.00012283387,0.000021143069,0.0000033952017,0.000011164664,0.00010949707,0.00000845695,0.0003524282],"genre_scores_gemma":[0.99864525,0.00015189851,0.00019835442,0.000048287406,0.000015965052,0.000020182237,0.0001988482,0.0000049726864,0.00071625505],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99989724,0.000011800698,0.000009466252,0.000029104325,0.000013854665,0.000038650145],"domain_scores_gemma":[0.9998658,0.000017815548,0.000046084413,0.000019658164,0.000019166373,0.000031426658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011775762,0.0002189027,0.00021076306,0.00027473818,0.00028375347,0.0003855805,0.000112680194,0.0002560506,0.0022527515],"category_scores_gemma":[0.00021060978,0.0001697084,0.00014684853,0.00014161551,0.0001864836,0.00021509128,0.00023187141,0.0002809624,0.00045534587],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078474334,0.00013222726,0.15188482,0.000103502876,0.000029896912,0.0027725515,0.0005187101,0.00005667916,0.8325802,0.00014977268,0.00022750588,0.0107594],"study_design_scores_gemma":[0.00006075577,0.0015137513,0.9017636,0.000041394,0.000071755654,0.016076768,0.0011619735,0.00033003607,0.07370648,0.00035275813,0.0049026883,0.00001812251],"about_ca_topic_score_codex":0.00023426488,"about_ca_topic_score_gemma":0.00029462297,"teacher_disagreement_score":0.0022527515,"about_ca_system_score_codex":0.00006645726,"about_ca_system_score_gemma":0.000046197787,"threshold_uncertainty_score":0.0075362325},"labels":[],"label_agreement":null},{"id":"W4406756853","doi":"10.1172/jci182584","title":"Neonatal but not juvenile gene therapy reduces seizures and prolongs lifespan in SCN1B–Dravet syndrome mice","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health; College of Pharmacy, University of Michigan; Medical School, University of Michigan; Ministerstvo Životního Prostředí; University of Michigan","keywords":"Dravet syndrome; Juvenile; Genetic enhancement; Medicine; Epilepsy; Bioinformatics; Gene; Endocrinology; Neuroscience; Biology; Internal medicine; Genetics; Psychiatry","score_opus":0.032493294989793337,"score_gpt":0.3260321485196078,"score_spread":0.29353885352981446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406756853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98405933,0.0031750356,0.0072820354,0.00046639104,0.00013685088,0.00009852235,0.0016944283,0.0007332981,0.0023540324],"genre_scores_gemma":[0.9788043,0.0040637567,0.0067207743,0.00029214946,0.000038094084,0.00025950087,0.0020621815,0.0002500005,0.0075092977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997409,0.000036297406,0.00004236201,0.000068193694,0.000069082795,0.00004317039],"domain_scores_gemma":[0.99967027,0.0000318265,0.00012514635,0.000022008393,0.000026426851,0.00012427435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027764394,0.00069621543,0.0005474107,0.0005007104,0.0001401618,0.00029231803,0.00040111798,0.0005847455,0.0016284969],"category_scores_gemma":[0.00021466985,0.00021490392,0.00036233713,0.00015911978,0.00033547595,0.0003152,0.0001999656,0.0010539332,0.0005064626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000103262035,0.00006271922,0.00013057217,0.000050901064,0.000008826099,0.000070002316,0.000019546333,0.00007661271,0.99760544,0.00011091307,0.00010679883,0.0016544433],"study_design_scores_gemma":[0.00028616213,0.00323267,0.008968094,0.000083101084,0.000116965995,0.0013360376,0.00009563618,0.002744399,0.97163004,0.00027578298,0.0111982105,0.00003287415],"about_ca_topic_score_codex":0.0006840152,"about_ca_topic_score_gemma":0.0014012407,"teacher_disagreement_score":0.0016284969,"about_ca_system_score_codex":0.00027805695,"about_ca_system_score_gemma":0.00028762335,"threshold_uncertainty_score":0.0054478645},"labels":[],"label_agreement":null},{"id":"W4406969198","doi":"10.1172/jci187024","title":"Elevated protein lactylation promotes immunosuppressive microenvironment and therapeutic resistance in pancreatic ductal adenocarcinoma","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"National Natural Science Foundation of China","keywords":"Pancreatic ductal adenocarcinoma; Cancer research; Tumor microenvironment; Adenocarcinoma; Medicine; Biology; Pancreatic cancer; Internal medicine; Immunology; Cancer; Tumor cells","score_opus":0.03386812966126453,"score_gpt":0.33072171010706813,"score_spread":0.2968535804458036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406969198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838483,0.0007207659,0.00028172162,0.000042847005,0.0000058577284,0.0000065641,0.000048933656,0.000030396264,0.00047811464],"genre_scores_gemma":[0.99909997,0.00031919187,0.000110271256,0.000020679146,0.000002831567,0.0000061936407,0.00007119309,0.0000042309607,0.00036536332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991333,0.0000152556895,0.000010530406,0.000016505404,0.000022272303,0.000022145729],"domain_scores_gemma":[0.99988997,0.000011908646,0.00003777532,0.000012324162,0.0000093639865,0.000038624883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117811745,0.00014351076,0.00019405397,0.00020571887,0.00013415162,0.00040853157,0.00007405985,0.00020211247,0.00093729043],"category_scores_gemma":[0.00012977603,0.00010196881,0.00019887324,0.00021830013,0.00017599107,0.00015576684,0.00020556847,0.00040719236,0.00021485085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010775548,0.0001409491,0.013955811,0.000066012195,0.000022128677,0.0006317776,0.00005619763,0.000187381,0.97697055,0.00012537073,0.00014721314,0.006619079],"study_design_scores_gemma":[0.00014464554,0.0028837728,0.29734084,0.000022648801,0.00013086331,0.0068695853,0.00050884165,0.003992944,0.6769711,0.0004492872,0.0106573505,0.00002817243],"about_ca_topic_score_codex":0.00021956657,"about_ca_topic_score_gemma":0.00020986669,"teacher_disagreement_score":0.00093729043,"about_ca_system_score_codex":0.0002551037,"about_ca_system_score_gemma":0.00013021546,"threshold_uncertainty_score":0.0031355023},"labels":[],"label_agreement":null},{"id":"W4407070174","doi":"10.1172/jci168730","title":"Translational regulation of SND1 governs endothelial homeostasis during stress","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; Chinese University of Hong Kong; Chicago Community Trust; University of California, San Francisco; American Heart Association","keywords":"Homeostasis; Cell biology; Posttranslational modification; Medicine; Chemistry; Biology; Biochemistry; Enzyme","score_opus":0.030197818831023127,"score_gpt":0.33633079806393373,"score_spread":0.3061329792329106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407070174","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987743,0.0032811854,0.0051699392,0.00018044068,0.00005435506,0.000018431101,0.0013399919,0.000102265854,0.0021102356],"genre_scores_gemma":[0.9955331,0.00071512384,0.0013394853,0.000072001916,0.0000084839185,0.000009818531,0.0012071537,0.000017458646,0.0010974219],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998753,0.000012599823,0.000009422219,0.00004833614,0.000028832288,0.000025479008],"domain_scores_gemma":[0.99992085,0.0000086904565,0.000028631599,0.000007006331,0.000018559824,0.000016192858],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014261273,0.00017861891,0.00016587849,0.00016417699,0.00022734208,0.00036836692,0.00012863959,0.00017319022,0.00084579206],"category_scores_gemma":[0.00012989438,0.00008445577,0.00024500993,0.00012578326,0.0001825331,0.00015117376,0.00014439927,0.00029467745,0.00023375262],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020154445,0.000018789347,0.0027471504,0.00005853582,0.000014901963,0.00007404443,0.000017701313,0.00026004325,0.9931665,0.0002877579,0.00017111235,0.002981999],"study_design_scores_gemma":[0.000013908572,0.00013628694,0.037556753,0.000009227551,0.000029424718,0.00028288958,0.000049313232,0.0040527014,0.9520318,0.00025505593,0.005568812,0.000013932017],"about_ca_topic_score_codex":0.00076556724,"about_ca_topic_score_gemma":0.0013622281,"teacher_disagreement_score":0.00084579206,"about_ca_system_score_codex":0.00047924242,"about_ca_system_score_gemma":0.00021420226,"threshold_uncertainty_score":0.0034770966},"labels":[],"label_agreement":null},{"id":"W4407070221","doi":"10.1172/jci174910","title":"Lactobacillus rhamnosus GG induces STING-dependent IL-10 in intestinal monocytes and alleviates inflammatory colitis in mice","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute; Agricultural Science and Technology Innovation Program; National Key Research and Development Program of China","keywords":"Lactobacillus rhamnosus; Colitis; Sting; Immunology; Microbiology; Medicine; Inflammatory Bowel Diseases; Lactobacillus; Monocyte; Inflammatory bowel disease; Biology; Internal medicine; Bacteria","score_opus":0.047076617500409125,"score_gpt":0.3401831277703086,"score_spread":0.2931065102698995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407070221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991799,0.001891387,0.0028431586,0.00038718208,0.00007287675,0.00009086237,0.0005995967,0.00030831352,0.0020077215],"genre_scores_gemma":[0.99110293,0.0011905563,0.003340289,0.00023129277,0.00002585377,0.00010607397,0.0005996987,0.000032255968,0.0033710478],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997743,0.000055697517,0.000022222022,0.000026158881,0.000039716113,0.0000819968],"domain_scores_gemma":[0.9998902,0.0000067825035,0.0000319312,0.0000117762975,0.000008009351,0.000051249073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021411873,0.0005035906,0.0003531649,0.00036389317,0.00011886786,0.00024056532,0.00013034751,0.00028415685,0.0011767889],"category_scores_gemma":[0.000090753834,0.00019086813,0.0003017503,0.0001606011,0.000298386,0.00014188071,0.00022610299,0.0012564218,0.00047904326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001069136,0.00020956344,0.00023228502,0.000070323134,0.000006213412,0.000062230225,0.00002034137,0.0000556737,0.99491537,0.00004365905,0.000095213734,0.0032200718],"study_design_scores_gemma":[0.00023785843,0.0049056956,0.008377394,0.00002713711,0.000035504312,0.0002848789,0.00007956356,0.0010831308,0.9821493,0.00009105963,0.0027185525,0.000009864807],"about_ca_topic_score_codex":0.00055127434,"about_ca_topic_score_gemma":0.0016209123,"teacher_disagreement_score":0.0011767889,"about_ca_system_score_codex":0.00022274128,"about_ca_system_score_gemma":0.00033988242,"threshold_uncertainty_score":0.003936708},"labels":[],"label_agreement":null},{"id":"W4407133319","doi":"10.1172/jci182931","title":"Sleep-wake variation in body temperature regulates tau secretion and correlates with CSF and plasma tau","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Fonds de Recherche du Québec - Santé; Alzheimer Society; Canadian Institutes of Health Research; National Institutes of Health; BrightFocus Foundation","keywords":"Secretion; Endocrinology; Internal medicine; Wake; Sleep (system call); Medicine; Biology; Chemistry; Psychology; Physics","score_opus":0.040692058797043504,"score_gpt":0.3419689701334892,"score_spread":0.3012769113364457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407133319","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99650264,0.0013644223,0.0012996185,0.000063433974,0.000021480537,0.000018307126,0.00024030129,0.00002889442,0.00046093934],"genre_scores_gemma":[0.9985702,0.00045716885,0.00035519188,0.000048890543,0.000011464805,0.000024936291,0.00017794034,0.0000067788874,0.000347339],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999478,0.0000124198095,0.0000058754035,0.000015164741,0.000008929051,0.000009893281],"domain_scores_gemma":[0.99983287,0.000015283613,0.00009451711,0.000015143894,0.000017619204,0.000024460067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010059566,0.00018986962,0.00016694496,0.00022395723,0.00010290353,0.00022749019,0.0000608178,0.00014524441,0.00069755065],"category_scores_gemma":[0.00023572169,0.00012143913,0.00016408403,0.00012893001,0.00024652766,0.0001253086,0.00016398363,0.0002703312,0.00010400545],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004266859,0.00024060106,0.25125116,0.00014256433,0.00025998065,0.0003231666,0.00026211917,0.0002763363,0.71454275,0.00018172609,0.0006142853,0.027638478],"study_design_scores_gemma":[0.000014517214,0.00034451892,0.9829874,0.000008942517,0.000039923503,0.00020214205,0.00006071147,0.0004430863,0.015391443,0.00009789906,0.00040282914,0.000006553176],"about_ca_topic_score_codex":0.0010340258,"about_ca_topic_score_gemma":0.0018564757,"teacher_disagreement_score":0.0010340258,"about_ca_system_score_codex":0.00018121063,"about_ca_system_score_gemma":0.00013150093,"threshold_uncertainty_score":0.0023335218},"labels":[],"label_agreement":null},{"id":"W4407353783","doi":"10.1172/jci187376","title":"Safety and efficacy of pharmacological inhibition of ketohexokinase in hereditary fructose intolerance","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Movement Disorders","funders":"","keywords":"Genetics; Fructose; Medicine; Biology; Bioinformatics; Biochemistry","score_opus":0.05181557271356562,"score_gpt":0.3981591772422845,"score_spread":0.3463436045287189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407353783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866174,0.010533782,0.00075918995,0.00022204773,0.00010749309,0.000070007685,0.00018033167,0.000022462604,0.0014872513],"genre_scores_gemma":[0.9978167,0.0014471181,0.00020424252,0.00013944716,0.00010291902,0.00003161444,0.00010621478,0.0000036855204,0.00014805619],"study_design_codex":"randomized_trial","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994211,0.00034635363,0.00006581772,0.000065717366,0.000065721506,0.000035249454],"domain_scores_gemma":[0.99811184,0.001071875,0.00028187005,0.00016354572,0.00013609146,0.00023478396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011442493,0.00034823574,0.0009002922,0.00038324884,0.00024785264,0.00032886572,0.00030872898,0.00073400466,0.00074345805],"category_scores_gemma":[0.0026431784,0.00010959655,0.00057026977,0.00028852336,0.0006028894,0.00041094687,0.00012436,0.0010605353,0.00011253932],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.597545,0.009507292,0.038893107,0.0015439556,0.0014849987,0.0012069006,0.0002397677,0.0018283523,0.087589435,0.0015359093,0.00069158844,0.25793365],"study_design_scores_gemma":[0.07715595,0.601756,0.1887291,0.00061918906,0.0034853972,0.0031994982,0.00041327457,0.0062785777,0.10899975,0.0016726181,0.0075666066,0.00012400436],"about_ca_topic_score_codex":0.0002927852,"about_ca_topic_score_gemma":0.00024972585,"teacher_disagreement_score":0.0011442493,"about_ca_system_score_codex":0.00031844672,"about_ca_system_score_gemma":0.00023435961,"threshold_uncertainty_score":0.006051421},"labels":[],"label_agreement":null},{"id":"W4408091719","doi":"10.1172/jci177241","title":"CRISPR-mediated detection of Pneumocystis transcripts in bronchoalveolar, oropharyngeal, and serum specimens for Pneumocystis pneumonia diagnosis","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pneumocystis jirovecii pneumonia detection and treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Institute for Health and Care Research","keywords":"Pneumonia; Pneumocystis pneumonia; Pneumocystis carinii; Bronchoalveolar lavage; Microbiology; Medicine; Virology; Immunology; Pneumocystis jirovecii; Biology; Lung; Internal medicine","score_opus":0.043100553466879896,"score_gpt":0.36576558511182883,"score_spread":0.3226650316449489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408091719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87456995,0.0013568235,0.11205452,0.00031595578,0.00015997436,0.0005381202,0.005444523,0.0022404974,0.0033197445],"genre_scores_gemma":[0.9199177,0.0007971996,0.07048234,0.00037929977,0.000029377636,0.0006644594,0.00360513,0.00015686725,0.0039676437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900764,0.00012687183,0.000094183124,0.0003219065,0.0003256448,0.00012379653],"domain_scores_gemma":[0.9993432,0.00014892923,0.00020798919,0.00008539034,0.00013437848,0.000080073565],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006580336,0.0004885484,0.0003796255,0.0005037416,0.00025541568,0.00047149742,0.00031050213,0.00058707024,0.0012429807],"category_scores_gemma":[0.0008863465,0.00033615262,0.00033067437,0.00017063817,0.00042662534,0.00018238244,0.00040021198,0.00061832817,0.00057405117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005092443,0.000017860357,0.001801381,0.00006133825,0.000009469847,0.000046078967,0.000041206127,0.00013359702,0.99511045,0.00008241025,0.00011777286,0.002527526],"study_design_scores_gemma":[0.000010284865,0.0003114283,0.008883024,0.000019880581,0.000030229246,0.00032124732,0.000053176616,0.0021854714,0.98523235,0.00009484278,0.0028420263,0.000016046826],"about_ca_topic_score_codex":0.0006409972,"about_ca_topic_score_gemma":0.0023725089,"teacher_disagreement_score":0.0012429807,"about_ca_system_score_codex":0.0004195671,"about_ca_system_score_gemma":0.00047020393,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W4408186354","doi":"10.1172/jci187711","title":"Macrophage-mediated IL-6 signaling drives ryanodine receptor–2 calcium leak in postoperative atrial fibrillation","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; European Commission","keywords":"Ryanodine receptor; Atrial fibrillation; Calcium; Leak; Receptor; Signal transduction; Medicine; Cardiology; Macrophage; Internal medicine; Endocrinology; Chemistry; Cell biology; Biology; Biochemistry; Engineering","score_opus":0.11789891127048086,"score_gpt":0.4240639204558283,"score_spread":0.30616500918534745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408186354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99542713,0.00079675514,0.0022926598,0.00015559659,0.000041140145,0.000017621174,0.00059311034,0.00006347856,0.000612459],"genre_scores_gemma":[0.9974322,0.00036785533,0.00069300306,0.00013959539,0.000019750632,0.000040002986,0.00042533418,0.00001988808,0.0008625409],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977356,0.00002126007,0.000021470547,0.00006775626,0.000049516493,0.00006652854],"domain_scores_gemma":[0.99985266,0.000016362383,0.00005137021,0.000014669272,0.00001627219,0.000048546164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021123301,0.0001795956,0.00027298986,0.00024084141,0.00023243981,0.00030479342,0.00012314797,0.00033435508,0.0016058038],"category_scores_gemma":[0.00022015124,0.00015738464,0.0003708148,0.00010145506,0.00027086807,0.00020568671,0.00028810307,0.0007750999,0.00044323705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060237455,0.000036279293,0.0052658524,0.00007474823,0.000013640865,0.00021273614,0.000074826836,0.00009179725,0.99104893,0.00013143796,0.0001564984,0.0022908521],"study_design_scores_gemma":[0.00026303093,0.0014405829,0.40458393,0.00012321312,0.00016292169,0.0037581893,0.0010800406,0.0054420484,0.57371885,0.0012872529,0.0080811735,0.00005882782],"about_ca_topic_score_codex":0.0002242273,"about_ca_topic_score_gemma":0.00036676537,"teacher_disagreement_score":0.0016058038,"about_ca_system_score_codex":0.00013527097,"about_ca_system_score_gemma":0.00016446969,"threshold_uncertainty_score":0.005371988},"labels":[],"label_agreement":null},{"id":"W4408491184","doi":"10.1172/jci185217","title":"Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Arthritis Society","funders":"National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health","keywords":"Immunophenotyping; Rheumatoid arthritis; Immunology; Medicine; Antigen","score_opus":0.062463567977857924,"score_gpt":0.38908535519224,"score_spread":0.3266217872143821,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408491184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99390465,0.0007892583,0.0034885702,0.0000849147,0.000013718045,0.000017675115,0.00066677143,0.00007007785,0.0009643667],"genre_scores_gemma":[0.9962393,0.00021939835,0.0021921431,0.0001895901,0.00002300364,0.000024346857,0.00047812244,0.0000108715185,0.0006232079],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998018,0.000038706614,0.000011095915,0.000075905315,0.00003379804,0.000038674883],"domain_scores_gemma":[0.9998722,0.00003586884,0.000029035507,0.000015554488,0.000022019683,0.00002519028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024730078,0.0002096311,0.00030135672,0.00063273904,0.0001615746,0.00059141347,0.00016935664,0.00039240727,0.0014594933],"category_scores_gemma":[0.00034265962,0.00014935654,0.00016381328,0.0002487174,0.00014946882,0.00016621366,0.00033017696,0.0003550065,0.0003609985],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000979765,0.00010237259,0.28394213,0.00016280309,0.00014232748,0.00044728923,0.00063404173,0.0008745329,0.664257,0.00029606957,0.0010188856,0.047142792],"study_design_scores_gemma":[0.00006579893,0.0008167069,0.90342927,0.0000777939,0.0003126801,0.0030315954,0.0012122709,0.01295551,0.069176435,0.0017239747,0.007150667,0.000047345846],"about_ca_topic_score_codex":0.00043852523,"about_ca_topic_score_gemma":0.0007205475,"teacher_disagreement_score":0.0014594933,"about_ca_system_score_codex":0.000103400256,"about_ca_system_score_gemma":0.00007392255,"threshold_uncertainty_score":0.004882455},"labels":[],"label_agreement":null},{"id":"W4408491188","doi":"10.1172/jci186889","title":"Cellular and molecular features of asthma mucus plugs provide clues about their formation and persistence","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; University of California, San Francisco; National Institutes of Health; National Heart, Lung, and Blood Institute; Wallonie-Bruxelles International; Fonds Léon Fredericq","keywords":"Persistence (discontinuity); Asthma; Mucus; Biology; Computational biology; Medicine; Immunology; Ecology","score_opus":0.034321048848055216,"score_gpt":0.33085650485908225,"score_spread":0.29653545601102704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408491188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906419,0.005716156,0.0020972225,0.000102924314,0.00001633358,0.000037054873,0.00050139136,0.00005629239,0.0008306629],"genre_scores_gemma":[0.9967789,0.00096887397,0.001529578,0.000033087534,0.000020100053,0.000022897306,0.00039683335,0.0000048581173,0.0002448987],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999863,0.000013872886,0.000014619329,0.00003031643,0.000030503983,0.000047603964],"domain_scores_gemma":[0.99988914,0.000012590532,0.00003691156,0.000009688146,0.000015664524,0.00003598268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169552,0.000285491,0.00025933867,0.00080554385,0.00025377236,0.0005181531,0.00019723072,0.0005989213,0.0014193241],"category_scores_gemma":[0.00016684501,0.00016578092,0.00026796447,0.00029608695,0.00025509542,0.000372702,0.00030142997,0.00032932125,0.0002639088],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022455277,0.000027516231,0.043284785,0.000116866446,0.000022525768,0.001001596,0.00007949817,0.000067150955,0.9506678,0.00018775405,0.00007423879,0.004245741],"study_design_scores_gemma":[0.000026636439,0.00072220835,0.74729264,0.00006316704,0.00010300841,0.013109416,0.0006743182,0.0018037965,0.23043033,0.00047972234,0.005273585,0.000021113561],"about_ca_topic_score_codex":0.0003646363,"about_ca_topic_score_gemma":0.00041085933,"teacher_disagreement_score":0.0014193241,"about_ca_system_score_codex":0.00017763043,"about_ca_system_score_gemma":0.00010341859,"threshold_uncertainty_score":0.0047481656},"labels":[],"label_agreement":null},{"id":"W4408563951","doi":"10.1172/jci181754","title":"Absence of the intracellular lipolytic inhibitor G0S2 enhances intravascular triglyceride clearance and abolishes diet-induced hypertriglyceridemia","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Hypertriglyceridemia; Triglyceride; Intracellular; Internal medicine; Endocrinology; Chemistry; Medicine; Biochemistry; Cholesterol","score_opus":0.030175314086885535,"score_gpt":0.32912638342824807,"score_spread":0.2989510693413625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408563951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99632794,0.0006583255,0.0014535647,0.00012712467,0.000041826705,0.000026520855,0.00024825984,0.00016325591,0.0009531187],"genre_scores_gemma":[0.99476695,0.00059082365,0.0018852978,0.00008954074,0.000018161023,0.000046804114,0.00048321075,0.00004793836,0.002071275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998242,0.000036586676,0.000022341452,0.00002964595,0.00004170137,0.000045538673],"domain_scores_gemma":[0.9998752,0.00001784241,0.000033573513,0.000012926165,0.000007328435,0.000053088323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015147043,0.00045601043,0.00040408032,0.0003609481,0.00012516529,0.00031381563,0.00025877776,0.0003371332,0.0009383426],"category_scores_gemma":[0.00012337422,0.00018111683,0.00024455623,0.00020483437,0.000534551,0.00022933543,0.00024267852,0.00081233954,0.0002747479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072256377,0.000121141,0.00014440651,0.000028691114,0.00000741415,0.000047057434,0.000014027462,0.000078298086,0.9974021,0.000119427685,0.0000586311,0.0012562989],"study_design_scores_gemma":[0.000092854185,0.0011918803,0.0019664138,0.0000056782355,0.000024661696,0.00013547193,0.000024757914,0.0009969237,0.9939017,0.000045653916,0.0016084592,0.000005474613],"about_ca_topic_score_codex":0.0006307088,"about_ca_topic_score_gemma":0.0010186378,"teacher_disagreement_score":0.0009383426,"about_ca_system_score_codex":0.0002952289,"about_ca_system_score_gemma":0.00030305487,"threshold_uncertainty_score":0.0031391382},"labels":[],"label_agreement":null},{"id":"W4408906767","doi":"10.1172/jci179881","title":"Prefrontal correlates of fear generalization during endocannabinoid depletion","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Mental Health; Vetenskapsrådet; Brain and Behavior Research Foundation","keywords":"Endocannabinoid system; Generalization; Neuroscience; Psychology; Medicine; Cognitive psychology; Psychiatry; Clinical psychology; Internal medicine; Mathematics; Receptor","score_opus":0.03853895658295742,"score_gpt":0.37563422956459674,"score_spread":0.3370952729816393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408906767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991749,0.000115150484,0.00035932165,0.000021840711,0.0000016094895,0.000004821978,0.0000820255,0.0000074608083,0.0002328765],"genre_scores_gemma":[0.9993795,0.000097127166,0.00019170935,0.000024480732,0.0000015525627,0.000009742045,0.000094165545,0.0000029110108,0.00019874348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999448,0.00000648143,0.0000021663907,0.00001773988,0.000015897014,0.000012915703],"domain_scores_gemma":[0.9998845,0.00001030764,0.000060825776,0.00001227422,0.000011017094,0.000021201156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000851385,0.00016875539,0.00019770593,0.00023386208,0.00010281495,0.00016542421,0.00009633225,0.00016197583,0.0007173766],"category_scores_gemma":[0.00022245198,0.00010959759,0.00008215135,0.00007589354,0.0003370956,0.000111444075,0.0002228987,0.00031499634,0.000051837356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001579072,0.00008002778,0.021478213,0.000029410268,0.000044371096,0.00028516218,0.00009465734,0.00012866942,0.9716741,0.00009860159,0.000057741436,0.004450088],"study_design_scores_gemma":[0.000015636091,0.00044222182,0.94441354,0.0000061927017,0.000029355722,0.00089935394,0.0001140454,0.00046740976,0.053201575,0.00021475661,0.00018756054,0.00000835082],"about_ca_topic_score_codex":0.0014584569,"about_ca_topic_score_gemma":0.0027972881,"teacher_disagreement_score":0.0014584569,"about_ca_system_score_codex":0.00022145377,"about_ca_system_score_gemma":0.00012307471,"threshold_uncertainty_score":0.0028999448},"labels":[],"label_agreement":null},{"id":"W4409415606","doi":"10.1172/jci175241","title":"Virus-associated inflammation imprints an inflammatory profile on monocyte-derived macrophages in the human liver","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Hospital for Sick Children; Princess Margaret Cancer Centre; University of Toronto; Toronto General Hospital; University Health Network; Schwartz/Reisman Emergency Medicine Institute; Toronto Liver Centre","funders":"Canadian Institutes of Health Research","keywords":"Inflammation; Monocyte; Immunology; Virus; Medicine; Biology; Virology","score_opus":0.0561577470107566,"score_gpt":0.37033548886113576,"score_spread":0.31417774185037917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409415606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838674,0.000444534,0.00058026344,0.000017598084,0.0000040958284,0.0000067273163,0.00024882957,0.0000101770665,0.00030106056],"genre_scores_gemma":[0.99846905,0.00016411605,0.0005681315,0.000031692154,0.0000033427855,0.000012262692,0.00029109564,0.000004542924,0.00045575332],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999044,0.000018318382,0.000005596352,0.000026960068,0.000017027145,0.000027715592],"domain_scores_gemma":[0.9999335,0.00001436077,0.000013687365,0.000011660524,0.0000144211845,0.0000123177415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013105341,0.00006408762,0.00015336396,0.00017707744,0.00015379496,0.0002689063,0.000040292205,0.00012341505,0.0007323858],"category_scores_gemma":[0.0001618156,0.000105502586,0.0000988249,0.0001665246,0.000114192706,0.000062015,0.000118940756,0.00016732456,0.00022865269],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036855732,0.000016546901,0.022818366,0.000033565957,0.000008707398,0.000071109505,0.00014160747,0.00008242092,0.971975,0.00008385733,0.00007757437,0.004322703],"study_design_scores_gemma":[0.0000329712,0.00048142474,0.604069,0.000030729192,0.000059477796,0.0007866062,0.0006843567,0.0020580771,0.3869212,0.00030157965,0.0045546186,0.000019780484],"about_ca_topic_score_codex":0.0007695279,"about_ca_topic_score_gemma":0.001304347,"teacher_disagreement_score":0.0007695279,"about_ca_system_score_codex":0.000111953406,"about_ca_system_score_gemma":0.0001420808,"threshold_uncertainty_score":0.0024501085},"labels":[],"label_agreement":null},{"id":"W4409528571","doi":"10.1172/jci179395","title":"Disruption of ataxia telangiectasia–mutated kinase enhances radiation therapy efficacy in spatially directed diffuse midline glioma models","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Hyundai Hope On Wheels; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health; St. Baldrick's Foundation; Pediatric Brain Tumor Foundation; Strong; ChadTough Foundation; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Ataxia-telangiectasia; Glioma; Cancer research; Medicine; Telangiectasia; Radiation therapy; Kinase; Pathology; Biology; Genetics; DNA; Internal medicine; DNA damage","score_opus":0.06218772051057839,"score_gpt":0.38545362114228215,"score_spread":0.3232659006317038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409528571","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957801,0.0005777387,0.0022349437,0.000045528515,0.000014478807,0.00004993086,0.00022232556,0.00013466248,0.00094021665],"genre_scores_gemma":[0.9951912,0.00051800604,0.0022968736,0.000024816858,0.000004332827,0.00004586065,0.00027254858,0.00002133532,0.0016249162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985874,0.000018430444,0.00001093846,0.00003444824,0.000038834536,0.000038587335],"domain_scores_gemma":[0.9999213,0.000008483934,0.00002537755,0.000008981609,0.0000068831237,0.000028846653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014709405,0.00043738048,0.0003316041,0.00039527248,0.00009686661,0.00022996735,0.00020125328,0.00022649483,0.0008609167],"category_scores_gemma":[0.00006099954,0.00014556023,0.00023390265,0.00016345832,0.0002222385,0.00015212975,0.00015543049,0.0006512059,0.00016484587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010446254,0.00008550021,0.000116815565,0.000018396911,0.000005639651,0.00002035737,0.000012689846,0.00010444939,0.998448,0.000055710963,0.00003631777,0.0009916042],"study_design_scores_gemma":[0.000016757569,0.0011527584,0.002100774,0.0000029856894,0.000018948655,0.00011418078,0.000014221233,0.0008068962,0.99511,0.000024566089,0.00063549995,0.0000025041234],"about_ca_topic_score_codex":0.00072519336,"about_ca_topic_score_gemma":0.0015725167,"teacher_disagreement_score":0.0008609167,"about_ca_system_score_codex":0.0002900104,"about_ca_system_score_gemma":0.0001646572,"threshold_uncertainty_score":0.0028800964},"labels":[],"label_agreement":null},{"id":"W4409737728","doi":"10.1172/jci191021","title":"Ketogenesis mitigates metabolic dysfunction–associated steatotic liver disease through mechanisms that extend beyond fat oxidation","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diet and metabolism studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health; University of Minnesota","keywords":"Ketogenesis; Beta oxidation; Disease; Fatty liver; Medicine; Bioinformatics; Endocrinology; Internal medicine; Ketone bodies; Biology; Metabolism","score_opus":0.08064255911523213,"score_gpt":0.35955924911990655,"score_spread":0.27891669000467445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409737728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9821838,0.006193943,0.009024274,0.00034297173,0.00014120048,0.0000758516,0.00034683492,0.00034423036,0.0013468928],"genre_scores_gemma":[0.99177516,0.0032237656,0.003221877,0.00013930611,0.000032133772,0.000040605242,0.0002878669,0.00003783666,0.0012414502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998672,0.00003005024,0.0000111632135,0.000023704006,0.00003393584,0.000033831497],"domain_scores_gemma":[0.99983144,0.000013303371,0.00005172883,0.000018621864,0.000025681808,0.000059283142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031438068,0.0005280997,0.0005573595,0.00044924626,0.00017267014,0.0005339887,0.00025214753,0.00032653537,0.0010954307],"category_scores_gemma":[0.00023104998,0.0001463351,0.0003207808,0.00017361366,0.00034850807,0.00048584284,0.0004884404,0.0008806478,0.00021003383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004405044,0.00058661925,0.0020850124,0.00037628206,0.00010248672,0.00010851402,0.000047920083,0.0007959725,0.9663577,0.00042082454,0.00021340072,0.02450015],"study_design_scores_gemma":[0.00051301613,0.012305262,0.03115781,0.00014449764,0.00038229013,0.00042090353,0.00020947232,0.005640197,0.93919426,0.0013418297,0.00864178,0.000048669386],"about_ca_topic_score_codex":0.00035989805,"about_ca_topic_score_gemma":0.00092150347,"teacher_disagreement_score":0.0010954307,"about_ca_system_score_codex":0.00019060606,"about_ca_system_score_gemma":0.00033229144,"threshold_uncertainty_score":0.0036646128},"labels":[],"label_agreement":null},{"id":"W4409906434","doi":"10.1172/jci190855","title":"DNA demethylating agents suppress preclinical models of synovial sarcoma","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Japan Society for the Promotion of Science; European Commission; Deutsches Krebsforschungszentrum; National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center","keywords":"Synovial sarcoma; DNA; Cancer research; Medicine; Sarcoma; Computational biology; Biology; Genetics; Pathology","score_opus":0.19226261916005719,"score_gpt":0.45014604079974874,"score_spread":0.2578834216396916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409906434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.974129,0.0062928083,0.0066981423,0.00066607347,0.00037818003,0.0006055929,0.0017237412,0.0007311431,0.008775286],"genre_scores_gemma":[0.98557496,0.0032405716,0.0025422366,0.00016080085,0.000039858052,0.00036195308,0.00146864,0.000027875976,0.00658319],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999851,0.000034668523,0.00001323465,0.000023584409,0.000036828435,0.000040633935],"domain_scores_gemma":[0.99985266,0.000020676813,0.000037681802,0.000021159036,0.00001869452,0.000049139864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025576953,0.00054378493,0.00045992495,0.00053315464,0.00016995535,0.0002715784,0.00032488527,0.0003656906,0.0028770647],"category_scores_gemma":[0.00018836124,0.00014834343,0.00025767405,0.00023094867,0.00027760532,0.00019785491,0.00013262432,0.0014436486,0.0005585814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023802025,0.002632095,0.0004413827,0.0002310222,0.00004239044,0.00016787037,0.000050130056,0.0005693765,0.9727787,0.0008291896,0.0010323147,0.018845368],"study_design_scores_gemma":[0.0007078875,0.017254526,0.0027232154,0.000038928283,0.000095844014,0.00046256903,0.00007878945,0.002421416,0.9628103,0.00039601905,0.012999089,0.000011432404],"about_ca_topic_score_codex":0.000591467,"about_ca_topic_score_gemma":0.0014797174,"teacher_disagreement_score":0.0028770647,"about_ca_system_score_codex":0.00033064914,"about_ca_system_score_gemma":0.00040465523,"threshold_uncertainty_score":0.00962472},"labels":[],"label_agreement":null},{"id":"W4409906436","doi":"10.1172/jci187862","title":"OCA-B promotes pathogenic maturation of stem-like CD4+ T cells and autoimmune demyelination","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Praespero","keywords":"Immunology; Stem cell; Autoimmunity; Medicine; Biology; Cell biology; Antibody","score_opus":0.032527875712360536,"score_gpt":0.3031510460539708,"score_spread":0.27062317034161026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409906436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99421644,0.0016027477,0.0014918721,0.00007134703,0.000020728707,0.00002020917,0.0004491034,0.00008077488,0.0020466968],"genre_scores_gemma":[0.99581736,0.0006764092,0.00096185505,0.00004682517,0.0000135779455,0.000028504639,0.0006396133,0.000019878335,0.0017959812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998597,0.000014257939,0.000009037049,0.000030854386,0.00004137421,0.000044798224],"domain_scores_gemma":[0.99991035,0.000006639398,0.000023455328,0.000011172983,0.00001082172,0.00003748029],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009410623,0.00026429404,0.00019586508,0.0003169396,0.00020899167,0.0003410984,0.000116238574,0.00021027609,0.0018422892],"category_scores_gemma":[0.000087157976,0.000100047975,0.00019754653,0.00017426147,0.0001774977,0.00016150683,0.00027514898,0.00036141204,0.00036152356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009347902,0.000021427773,0.00058372016,0.000030263975,0.0000044416975,0.00002439074,0.000010923475,0.00003785805,0.99691534,0.0000679933,0.000037824197,0.0021723034],"study_design_scores_gemma":[0.000039249688,0.000548117,0.035558064,0.000021650965,0.000039407667,0.00061350135,0.00008209566,0.000962212,0.9503814,0.0001869568,0.011560845,0.000006554116],"about_ca_topic_score_codex":0.0007152287,"about_ca_topic_score_gemma":0.0012380518,"teacher_disagreement_score":0.0018422892,"about_ca_system_score_codex":0.00021855775,"about_ca_system_score_gemma":0.00026313594,"threshold_uncertainty_score":0.0061630607},"labels":[],"label_agreement":null},{"id":"W4410004411","doi":"10.1172/jci192414","title":"GLP-1 receptor agonists for the treatment of alcohol use disorder","year":2025,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"Alcohol use disorder; Alcohol; Receptor; Pharmacology; Agonist; Medicine; Chemistry; Internal medicine; Biochemistry","score_opus":0.14370850584484934,"score_gpt":0.4054309508184011,"score_spread":0.26172244497355174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410004411","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019470856,0.005897565,0.00029855155,0.91666996,0.060082335,0.00006977675,0.000092524,0.0001452153,0.014797074],"genre_scores_gemma":[0.017502513,0.011376955,0.0008275221,0.7966819,0.14101279,0.000094058436,0.00012489986,0.00006498216,0.03231444],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993223,0.00019801075,0.00008341626,0.00007151401,0.00024811042,0.00007669167],"domain_scores_gemma":[0.9984785,0.0005924076,0.00011386168,0.0000541743,0.00044816683,0.00031292994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007636852,0.0006054302,0.00062469085,0.0005962225,0.0014121683,0.0012102356,0.0006412975,0.010096561,0.007177775],"category_scores_gemma":[0.0066275187,0.00029912827,0.0008160407,0.00039203337,0.0009594136,0.001311493,0.00036298626,0.011770308,0.008636806],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009693774,0.00011744175,0.00088998815,0.00009696122,0.000016886333,0.0060422136,0.000050180784,0.00007336502,0.000332491,0.0010912092,0.96302706,0.02816531],"study_design_scores_gemma":[0.00033424643,0.00021196659,0.0029910058,0.0005492183,0.00004661375,0.018741677,0.0002230053,0.00095155044,0.0006057174,0.005267148,0.9700338,0.000044112476],"about_ca_topic_score_codex":0.0018154667,"about_ca_topic_score_gemma":0.003795986,"teacher_disagreement_score":0.010096561,"about_ca_system_score_codex":0.0018421025,"about_ca_system_score_gemma":0.0014116518,"threshold_uncertainty_score":0.02401203},"labels":[],"label_agreement":null},{"id":"W4410004544","doi":"10.1172/jci191907","title":"The differential effects of sex hormone therapy on kidney function: insights into biological sex differences","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Sex and Gender in Healthcare","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of Alberta","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Sex hormone-binding globulin; Hormone; Function (biology); Differential effects; Sex characteristics; Hormone therapy; Differential (mechanical device); Medicine; Physiology; Internal medicine; Biology; Bioinformatics; Evolutionary biology","score_opus":0.1237071417206408,"score_gpt":0.405519888355408,"score_spread":0.2818127466347672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410004544","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5116138,0.4138969,0.0064602774,0.039517906,0.002681113,0.00010359905,0.003468794,0.00007254457,0.022185037],"genre_scores_gemma":[0.90506864,0.076551095,0.0026044277,0.010004161,0.0029535587,0.000044853772,0.00082132465,0.00004630058,0.0019055728],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989397,0.0004095339,0.00009825936,0.00016817226,0.00027940227,0.000105032166],"domain_scores_gemma":[0.9961177,0.0025544737,0.0004703924,0.00038915238,0.0003226048,0.00014566643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00267998,0.00027901508,0.0006512015,0.0006509046,0.0002519104,0.001339026,0.00038882042,0.000562169,0.0024044341],"category_scores_gemma":[0.00598382,0.00014558717,0.0007436062,0.0007427241,0.0008492841,0.0007183189,0.0005049543,0.0008190836,0.0002575009],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003386689,0.00027852657,0.61912394,0.0022047453,0.0020247805,0.0007407257,0.0014935491,0.00039444683,0.0075447815,0.008837183,0.013208284,0.34076235],"study_design_scores_gemma":[0.00015911733,0.0009698074,0.9139765,0.0008742579,0.0012356073,0.0019214305,0.0011352116,0.0007505065,0.0032954335,0.012611869,0.062996835,0.00007347992],"about_ca_topic_score_codex":0.001266647,"about_ca_topic_score_gemma":0.0022675833,"teacher_disagreement_score":0.00267998,"about_ca_system_score_codex":0.00042129972,"about_ca_system_score_gemma":0.00051837636,"threshold_uncertainty_score":0.01417321},"labels":[],"label_agreement":null},{"id":"W4410345613","doi":"10.1172/jci172988","title":"LAG3 regulates antibody responses in a murine model of kidney transplantation","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; American Society of Transplantation","keywords":"Transplantation; Kidney transplantation; Antibody; Immunology; Biology; Medicine; Cell biology; Cancer research; Internal medicine","score_opus":0.08851183993508466,"score_gpt":0.4386177811011775,"score_spread":0.35010594116609284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410345613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99464345,0.0013919274,0.0018690763,0.00018100132,0.00008522739,0.000087823595,0.00039150423,0.0001393391,0.0012105759],"genre_scores_gemma":[0.99424213,0.00074855675,0.0016822278,0.00014592463,0.000025772188,0.0001158491,0.00043914976,0.00002468537,0.0025757595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973077,0.000055190463,0.000026691216,0.000041652045,0.000058590816,0.000086991895],"domain_scores_gemma":[0.99975556,0.000025732123,0.00008046356,0.000024370027,0.000022270422,0.000091634196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000343837,0.00055695215,0.00033649136,0.000739097,0.00029035402,0.00047585682,0.00028348522,0.0006105702,0.0014501453],"category_scores_gemma":[0.00016940219,0.00019459444,0.00044794867,0.00020321371,0.00042688247,0.0003681603,0.00023498433,0.0017455103,0.00031755966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009472779,0.0005534702,0.00044147478,0.000046899808,0.0000080174605,0.000094043826,0.000032989134,0.00015892014,0.99613357,0.00015110262,0.000081348335,0.0013507608],"study_design_scores_gemma":[0.00034701996,0.0067134206,0.010887748,0.00003562036,0.00007975346,0.0005277118,0.00010308294,0.003557126,0.97407657,0.00030837368,0.003337736,0.00002585019],"about_ca_topic_score_codex":0.00067342795,"about_ca_topic_score_gemma":0.001102253,"teacher_disagreement_score":0.0014501453,"about_ca_system_score_codex":0.000564389,"about_ca_system_score_gemma":0.00037044272,"threshold_uncertainty_score":0.004851222},"labels":[],"label_agreement":null},{"id":"W4410930193","doi":"10.1172/jci180190","title":"4E-BP1–dependent translation in microglia controls mechanical hypersensitivity in male and female mice","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Microglia; Translation (biology); Medicine; Immunology; Neuroscience; Pathology; Biology; Inflammation; Genetics","score_opus":0.10501605039489154,"score_gpt":0.35976996949390055,"score_spread":0.254753919099009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410930193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885111,0.0020252648,0.0040826276,0.0005028242,0.00016496383,0.00013141669,0.002238556,0.000291507,0.0020517434],"genre_scores_gemma":[0.9726753,0.0021965285,0.0047527147,0.00037578386,0.000098509096,0.0005441362,0.0019065834,0.00040656846,0.017043805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905246,0.0001277622,0.000076554425,0.00029787986,0.00020682473,0.00023842277],"domain_scores_gemma":[0.9992244,0.00004892621,0.00034446662,0.000059458107,0.000051786297,0.00027090305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055404246,0.0012953109,0.00073505257,0.0028106824,0.0008044361,0.0007342184,0.0005818066,0.0012869867,0.0042765248],"category_scores_gemma":[0.00027988816,0.00090479705,0.00086864666,0.00046546877,0.0013243683,0.00068161014,0.0005262167,0.002051994,0.0013532464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008204004,0.00025289238,0.00034567714,0.000033445416,0.0000081105345,0.00011565809,0.000068718866,0.000031585198,0.9969773,0.0001659341,0.000080522674,0.0010997972],"study_design_scores_gemma":[0.00030198097,0.0022744625,0.02585213,0.00004946172,0.00008193869,0.0009999893,0.00027438445,0.0010489806,0.9648277,0.00029996777,0.0039334754,0.000055443124],"about_ca_topic_score_codex":0.0010733636,"about_ca_topic_score_gemma":0.002189972,"teacher_disagreement_score":0.0042765248,"about_ca_system_score_codex":0.00081925385,"about_ca_system_score_gemma":0.00046926428,"threshold_uncertainty_score":0.014306366},"labels":[],"label_agreement":null},{"id":"W4410930202","doi":"10.1172/jci183796","title":"PIEZO1 mediates mechanical reprogramming of neutrophils for proangiogenic specialization in the lung","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; McGill University","funders":"National Natural Science Foundation of China","keywords":"Reprogramming; Lung; Cell biology; Biology; Immunology; Chemistry; Medicine; Cell; Internal medicine; Genetics","score_opus":0.08271715039313383,"score_gpt":0.40650811361411887,"score_spread":0.32379096322098505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410930202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99549615,0.00068726635,0.0025724042,0.00016516728,0.000022154105,0.000023444898,0.00014075958,0.000029444855,0.0008631584],"genre_scores_gemma":[0.9983791,0.00020622558,0.00045428707,0.00005297544,0.0000061067085,0.000019020299,0.00008252938,0.0000037418558,0.0007961498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998548,0.000023555096,0.000010318605,0.00002927121,0.000036199934,0.00004574866],"domain_scores_gemma":[0.9999161,0.000011875919,0.000029748964,0.0000075579637,0.0000067697288,0.000027932338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018757944,0.00012737577,0.00014042118,0.00009407957,0.00013507454,0.00031462687,0.00012810025,0.00024778058,0.001195039],"category_scores_gemma":[0.00016428615,0.000089340734,0.000112716945,0.000054227068,0.00024298416,0.00018867059,0.00021591586,0.00045514817,0.00018082712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078306024,0.000017441487,0.0005107078,0.000022392216,0.0000016247574,0.000061326034,0.00001549412,0.000047430145,0.99803215,0.0001602116,0.000034400397,0.0010184502],"study_design_scores_gemma":[0.000040784947,0.00027852802,0.04611044,0.000015792602,0.000014521519,0.0005231378,0.00019237383,0.0026839578,0.9470902,0.00022891891,0.0028134692,0.00000782909],"about_ca_topic_score_codex":0.00024550754,"about_ca_topic_score_gemma":0.0004035377,"teacher_disagreement_score":0.001195039,"about_ca_system_score_codex":0.00019396776,"about_ca_system_score_gemma":0.0001713327,"threshold_uncertainty_score":0.0039978027},"labels":[],"label_agreement":null},{"id":"W4410930213","doi":"10.1172/jci187490","title":"PROX1 is an early driver of lineage plasticity in prostate cancer","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Institute for Prostate Cancer Research; Terry Fox Research Institute; National Cancer Institute; National Institutes of Health; BC Cancer Foundation; Prostate Cancer Foundation","keywords":"Prostate cancer; Lineage (genetic); Prostate; Plasticity; Biology; Cancer research; Cancer; Internal medicine; Medicine; Oncology; Genetics; Gene; Physics","score_opus":0.11794641767646559,"score_gpt":0.4652361321358967,"score_spread":0.34728971445943113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410930213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829321,0.006202828,0.006430712,0.00022419149,0.000022059881,0.00006078604,0.00086598087,0.00013980287,0.0031215057],"genre_scores_gemma":[0.99364626,0.0020510617,0.001747505,0.000051915355,0.000008779325,0.000017858589,0.00053758355,0.00001526709,0.0019238007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998894,0.000012345164,0.000005136776,0.000022202465,0.000046282556,0.000024677156],"domain_scores_gemma":[0.99993145,0.000008165556,0.000020317024,0.0000056361064,0.000010041843,0.000024509558],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117452364,0.00017377199,0.00017649068,0.00028726377,0.00024348739,0.00042588805,0.00012236802,0.00013372811,0.001274282],"category_scores_gemma":[0.00012018654,0.00016454844,0.00014260907,0.00023198396,0.00019071187,0.00027074388,0.0002879523,0.0004974121,0.00023104933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014534911,0.000013772097,0.0033008729,0.0000735603,0.0000080425525,0.00007110811,0.00003479342,0.00020086432,0.9888404,0.00047824165,0.000116155716,0.0067168036],"study_design_scores_gemma":[0.000013752324,0.00041054562,0.07818407,0.00001679826,0.000042423366,0.0009173918,0.00014063642,0.002163179,0.9029293,0.0002851781,0.014877687,0.000018963441],"about_ca_topic_score_codex":0.0010298,"about_ca_topic_score_gemma":0.0021650828,"teacher_disagreement_score":0.001274282,"about_ca_system_score_codex":0.00034620755,"about_ca_system_score_gemma":0.00038363322,"threshold_uncertainty_score":0.004262924},"labels":[],"label_agreement":null},{"id":"W4411176523","doi":"10.1172/jci186065","title":"TNF-α impairs platelet function by inhibiting autophagy and disrupting metabolism via syntaxin 17 downregulation","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bioinformatics Solutions (Canada)","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; University of Colorado School of Medicine, Anschutz Medical Campus; Anschutz Medical Campus, University of Colorado; Uniformed Services University of the Health Sciences","keywords":"Downregulation and upregulation; Autophagy; Cell biology; Function (biology); Metabolism; Chemistry; Platelet; Tumor necrosis factor alpha; Biology; Immunology; Biochemistry; Gene; Apoptosis","score_opus":0.027540655677919582,"score_gpt":0.35635126729433847,"score_spread":0.3288106116164189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411176523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99118865,0.004467528,0.0021201004,0.00022329386,0.00006729006,0.000031573967,0.0003169148,0.00007332616,0.0015113314],"genre_scores_gemma":[0.99521184,0.0020440477,0.0011736623,0.000079701174,0.000012721638,0.000036681897,0.00025277992,0.000008572468,0.0011801204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998485,0.000036503916,0.000029812158,0.000021460568,0.000027585102,0.000036233214],"domain_scores_gemma":[0.9999244,0.000009929677,0.00003071675,0.000009255636,0.00000802755,0.000017635544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001852655,0.00024869392,0.00026334226,0.00018373692,0.00014367027,0.0003315042,0.00012477658,0.00022881148,0.0007732224],"category_scores_gemma":[0.0001103578,0.00010360436,0.0003183921,0.00015734427,0.00025035595,0.00021888141,0.00012582033,0.0005085417,0.00018044922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00096829183,0.0001036974,0.00048689562,0.00011856605,0.000023833234,0.00012542157,0.000022995777,0.00018084096,0.99447894,0.00027437546,0.00011923347,0.0030968618],"study_design_scores_gemma":[0.00011209041,0.0012356668,0.004735842,0.000020307649,0.000056870245,0.00059137197,0.00005796537,0.0013107779,0.98827153,0.00014619193,0.0034544675,0.000006891752],"about_ca_topic_score_codex":0.00038036978,"about_ca_topic_score_gemma":0.00052002806,"teacher_disagreement_score":0.0007732224,"about_ca_system_score_codex":0.00026997316,"about_ca_system_score_gemma":0.00032870146,"threshold_uncertainty_score":0.0025866628},"labels":[],"label_agreement":null},{"id":"W4411488183","doi":"10.1172/jci177430","title":"Neuraminidase 1 secondary deficiency contributes to CNS pathology in neurological mucopolysaccharidoses via brain protein hypersialylation","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; Université de Montréal; University of Alberta; McGill University; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian MPS Society for Mucopolysaccharide and Related Diseases; National Institute of General Medical Sciences; Canadian Glycomics Network; Canadian Institutes of Health Research; Sanfilippo Children's Foundation","keywords":"Mucopolysaccharidosis; Lysosomal storage disease; Polysialic acid; Biology; Cathepsin A; Neuraminidase; Cathepsin D; Glycan; Sialidase; Pathology; Cell biology; Neuroscience; Glycoprotein; Medicine; Biochemistry; Enzyme","score_opus":0.056519394432058286,"score_gpt":0.39154911086544214,"score_spread":0.33502971643338386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411488183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99247324,0.0023163655,0.001843564,0.00017211407,0.000057443878,0.000058328733,0.0006338793,0.00019117068,0.0022537855],"genre_scores_gemma":[0.9929275,0.0023492314,0.0011691786,0.00009398838,0.000021891032,0.000051955238,0.00076098077,0.00003955193,0.002585699],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999131,0.000010535075,0.00001601587,0.000026270323,0.000020458956,0.0000136741955],"domain_scores_gemma":[0.9998925,0.000006570884,0.00003682817,0.000009968507,0.000010738111,0.00004346336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008620362,0.0010650723,0.0003551304,0.00051566196,0.0002031769,0.00025447062,0.00030686826,0.00039693242,0.0020210808],"category_scores_gemma":[0.000120047276,0.00016202757,0.00027930678,0.00018436623,0.00045578618,0.00017613477,0.0004392561,0.00069747353,0.00061139825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024966706,0.00005117232,0.0007575971,0.00011221385,0.000026303998,0.002169142,0.000026265947,0.00007808355,0.9939229,0.00014247907,0.00015948075,0.0023046613],"study_design_scores_gemma":[0.0001313662,0.0009586402,0.069293395,0.00008867228,0.00033100095,0.02898948,0.00022400725,0.0018418999,0.8897538,0.000979272,0.0073686987,0.00003965204],"about_ca_topic_score_codex":0.0009793013,"about_ca_topic_score_gemma":0.0008154713,"teacher_disagreement_score":0.0020210808,"about_ca_system_score_codex":0.00033817283,"about_ca_system_score_gemma":0.0003812979,"threshold_uncertainty_score":0.0067611933},"labels":[],"label_agreement":null},{"id":"W4411872495","doi":"10.1172/jci184043","title":"Targeting immune checkpoint LAIR1 with antibody blockade or 3-in-1 CAR T cells enhances antitumor response","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute","keywords":"Blockade; Blocking (statistics); Blocking antibody; Immune system; Immune checkpoint; Antibody; Immunology; Cancer research; Medicine; Chemistry; Immunotherapy; Receptor; Computer science; Internal medicine","score_opus":0.05981472004056149,"score_gpt":0.43013826727697013,"score_spread":0.37032354723640865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411872495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99351513,0.001998887,0.001943843,0.00016360277,0.00007005747,0.0000812732,0.00016616663,0.0002535994,0.0018072989],"genre_scores_gemma":[0.99609804,0.0006751518,0.0012417753,0.00010437921,0.00003226949,0.000056199882,0.00018711726,0.000017717028,0.0015873963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979895,0.000027724143,0.000012414338,0.000032223936,0.000038300677,0.000090447895],"domain_scores_gemma":[0.99992156,0.000011734391,0.00002085348,0.0000090492595,0.000007057417,0.000029777597],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016036085,0.0004792673,0.00062988914,0.00025660955,0.00010588053,0.00026162073,0.00021091363,0.00047447128,0.0013156855],"category_scores_gemma":[0.00009004147,0.00012718957,0.0003321103,0.00011801368,0.00019620548,0.00022158388,0.00014372835,0.0013810219,0.00039873485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048807258,0.0002899277,0.00014487312,0.00007281261,0.0000106848665,0.000034544828,0.00001698689,0.00021125867,0.99418044,0.000079956044,0.00019625909,0.0042742486],"study_design_scores_gemma":[0.00016643979,0.003524527,0.0030898573,0.000010913561,0.00006292557,0.00035602195,0.000026149553,0.0021999166,0.9869042,0.00006944671,0.0035810817,0.0000084168505],"about_ca_topic_score_codex":0.0003870842,"about_ca_topic_score_gemma":0.0005750237,"teacher_disagreement_score":0.0013156855,"about_ca_system_score_codex":0.00025981362,"about_ca_system_score_gemma":0.00029327357,"threshold_uncertainty_score":0.004401386},"labels":[],"label_agreement":null},{"id":"W4411872561","doi":"10.1172/jci188530","title":"Targeting the IL-36 receptor with spesolimab mitigates residual inflammation and prevents generalized pustular psoriasis flares","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Psoriasis; Inflammation; Generalized pustular psoriasis; Medicine; Pustular psoriasis; Immunology; Receptor; Dermatology; Internal medicine","score_opus":0.032138088779788146,"score_gpt":0.30661382459766606,"score_spread":0.27447573581787793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411872561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95636386,0.024800397,0.0072291186,0.0019135356,0.0005450134,0.00019873148,0.0003453246,0.0011064064,0.0074975668],"genre_scores_gemma":[0.99030274,0.0040023304,0.0021370808,0.0003524924,0.00009704984,0.000055349985,0.00027549095,0.000032399977,0.002745058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997862,0.000045136916,0.000014488698,0.000020364234,0.000046757912,0.0000870769],"domain_scores_gemma":[0.9999293,0.0000071788727,0.000018429162,0.000009108796,0.000009336675,0.000026582042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024256378,0.00035334795,0.00053067086,0.00025971132,0.00016311469,0.00037755817,0.00024353314,0.0004205862,0.0037359153],"category_scores_gemma":[0.00022706567,0.00013960931,0.00048002877,0.00012578507,0.00028630436,0.00035581226,0.0001989307,0.0012419772,0.00089257397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007437294,0.0018104123,0.001168759,0.0007077864,0.00015370952,0.00035837977,0.00008357975,0.0011612783,0.78543335,0.00071959087,0.006535768,0.19443002],"study_design_scores_gemma":[0.008102874,0.057346977,0.03496893,0.0003731768,0.0005297335,0.006683797,0.0004973952,0.008384451,0.78040385,0.002440566,0.100175016,0.00009322598],"about_ca_topic_score_codex":0.00048619698,"about_ca_topic_score_gemma":0.0008436598,"teacher_disagreement_score":0.0037359153,"about_ca_system_score_codex":0.00016927108,"about_ca_system_score_gemma":0.00033074024,"threshold_uncertainty_score":0.012497902},"labels":[],"label_agreement":null},{"id":"W4412430336","doi":"10.1172/jci168962","title":"Organ-specific features of human kidney lymphatics are disrupted in chronic transplant rejection","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Foulkes Foundation; Rosetrees Trust; Kidney Research UK; National Institute for Health and Care Research; Wellcome Trust","keywords":"Lymphatic system; Kidney; Kidney transplantation; Pathology; Medicine; Organ transplantation; Graft rejection; Transplant rejection; Immunology; Transplantation; Biology; Immune system; Internal medicine","score_opus":0.03431954953857322,"score_gpt":0.3447410962103921,"score_spread":0.31042154667181887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412430336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974215,0.00054415176,0.0013790239,0.000024335031,0.0000032789223,0.0000055463493,0.00010702105,0.000028186465,0.00048694646],"genre_scores_gemma":[0.9989668,0.00025347222,0.00033919222,0.000010065082,0.0000026134949,0.00000406206,0.00010786334,0.0000055894307,0.0003103324],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99990034,0.000018722425,0.000008659552,0.000025571102,0.000025424135,0.000021287235],"domain_scores_gemma":[0.99987936,0.000013941749,0.00006309263,0.000013781281,0.000007529406,0.000022315044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016135121,0.00013102018,0.00013964846,0.00030685536,0.00010325974,0.0002813479,0.00009361074,0.00014266252,0.0011063298],"category_scores_gemma":[0.0001874089,0.000078747566,0.00010107189,0.00022629602,0.00024810657,0.00014593254,0.0002613191,0.00018446434,0.00014771053],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006797146,0.000027771535,0.03176041,0.00006837732,0.000022051545,0.0013977917,0.00014877689,0.00016856927,0.9552265,0.00047550414,0.000072118295,0.009952495],"study_design_scores_gemma":[0.000036269746,0.0004756993,0.58663917,0.000018329114,0.000099482895,0.023309119,0.00049739005,0.0011523425,0.3806416,0.0009516323,0.0061574066,0.000021688638],"about_ca_topic_score_codex":0.00021334618,"about_ca_topic_score_gemma":0.00019185121,"teacher_disagreement_score":0.0011063298,"about_ca_system_score_codex":0.00010928243,"about_ca_system_score_gemma":0.0001473473,"threshold_uncertainty_score":0.0037010312},"labels":[],"label_agreement":null},{"id":"W4412492077","doi":"10.1172/jci187371","title":"Aggressive B cell lymphomas retain ATR-dependent determinants of T cell exclusion from the germinal center dark zone","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre","funders":"National Medical Research Council; Medical Research Council; National Cancer Institute; National Institutes of Health; Associazione Italiana per la Ricerca sul Cancro; Ministero dell’Istruzione, dell’Università e della Ricerca; European Commission; Università degli Studi di Milano","keywords":"Germinal center; Biology; B cell; Immune system; T cell; Cell; Transcriptome; Cancer research; Cell biology; Molecular biology; Immunology; Gene expression; Antibody; Genetics; Gene","score_opus":0.030745013754318016,"score_gpt":0.31081970261875674,"score_spread":0.2800746888644387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412492077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955987,0.0008915661,0.0024608008,0.0000294391,0.000004902606,0.000012804912,0.00012683081,0.00007022642,0.0008047024],"genre_scores_gemma":[0.9980824,0.0002229193,0.0007784426,0.000021796617,0.0000029372973,0.000010961699,0.00019807123,0.000009690286,0.00067284994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986017,0.000021710894,0.0000097818265,0.000035818368,0.000038769944,0.000033782253],"domain_scores_gemma":[0.9999037,0.000017377208,0.000028141509,0.000016154223,0.000010024618,0.000024651541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011503512,0.00015318056,0.00018900423,0.00016732918,0.00008514872,0.00034623596,0.000105742096,0.00015892948,0.0007179713],"category_scores_gemma":[0.00009804357,0.00010391583,0.00011887658,0.00009822746,0.00021906137,0.00014044622,0.00014238284,0.0005313435,0.00028965727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045125344,0.000008176612,0.00027310287,0.0000092201235,0.000001778301,0.000017660523,0.0000060795537,0.000024193301,0.9988961,0.000029480823,0.000005605535,0.0006834269],"study_design_scores_gemma":[0.000015910698,0.00039026837,0.017326027,0.000004250615,0.000018008923,0.0004321311,0.00004767471,0.00095008756,0.9789412,0.00011214519,0.0017590725,0.0000032352673],"about_ca_topic_score_codex":0.00018941899,"about_ca_topic_score_gemma":0.0003099275,"teacher_disagreement_score":0.0007179713,"about_ca_system_score_codex":0.00012058086,"about_ca_system_score_gemma":0.00010810295,"threshold_uncertainty_score":0.0024018288},"labels":[],"label_agreement":null},{"id":"W4412711430","doi":"10.1172/jci192589","title":"Reduced vaccine-induced germinal center outputs in patients with inflammatory bowel disease treated with anti-TNF biologics","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Krembil Foundation; University of Toronto","funders":"Institute of Genetics; Canadian Institutes of Health Research; University of Toronto; Gilead Sciences; Amgen; Pfizer; Canada Research Chairs; Government of Ontario; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Inflammatory bowel disease; Germinal center; Medicine; Tumor necrosis factor alpha; Disease; Infliximab; Center (category theory); Immunology; Internal medicine; Antibody; Chemistry","score_opus":0.018031840978464057,"score_gpt":0.2990190200965459,"score_spread":0.28098717911808185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412711430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986945,0.00058225164,0.0001480422,0.00004643434,0.000009344722,0.000013120372,0.00009748127,0.000015816502,0.00039312462],"genre_scores_gemma":[0.9994618,0.00009687815,0.00010927357,0.00004539735,0.0000088503275,0.000009991513,0.00013617653,0.0000025870836,0.00012900683],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998338,0.00004530476,0.00001987979,0.00004125982,0.0000239113,0.00003575381],"domain_scores_gemma":[0.9994997,0.0000781752,0.00022287952,0.00002757832,0.000051002135,0.00012066698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023565607,0.00030152168,0.00047503397,0.00045911767,0.00024828975,0.00032507768,0.00011358358,0.00035738215,0.0015679142],"category_scores_gemma":[0.0007891099,0.00011805116,0.00025179726,0.00023499508,0.0001789527,0.00020477168,0.0001679353,0.00051821506,0.00017703086],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010591148,0.0007006486,0.8291272,0.0002820757,0.00022905554,0.0023363463,0.00045357106,0.0003339964,0.12282044,0.00014406933,0.0006307287,0.032350797],"study_design_scores_gemma":[0.00016105844,0.004635949,0.98257786,0.00002261155,0.00012118043,0.0035832827,0.0001753762,0.0004758035,0.006778884,0.000080723104,0.0013781927,0.000009118467],"about_ca_topic_score_codex":0.00025164415,"about_ca_topic_score_gemma":0.00023678874,"teacher_disagreement_score":0.0015679142,"about_ca_system_score_codex":0.00018211153,"about_ca_system_score_gemma":0.000096755095,"threshold_uncertainty_score":0.005245149},"labels":[],"label_agreement":null},{"id":"W4412711468","doi":"10.1172/jci194081","title":"Factors associated with resistance of HIV-1 reservoir viruses to neutralization by autologous IgG antibodies","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Maple Leaf Medical Clinic","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Philadelphia Foundation; Howard Hughes Medical Institute","keywords":"Neutralization; Antibody; Virology; Immunology; Human immunodeficiency virus (HIV); Immunoglobulin G; Biology; Medicine","score_opus":0.15473638746877152,"score_gpt":0.4317657978513087,"score_spread":0.27702941038253714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412711468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983425,0.00066081836,0.00016577037,0.000045483197,0.0000042108773,0.00001650077,0.0001332043,0.00000978543,0.0006217121],"genre_scores_gemma":[0.99951386,0.00008781086,0.00008403811,0.000011741021,0.000005809938,0.000005133153,0.000081551945,0.0000031909028,0.00020689222],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99971575,0.00006542116,0.000026116122,0.000060477574,0.000063547,0.000068719535],"domain_scores_gemma":[0.998771,0.00037282225,0.0005326211,0.000084663596,0.000104781735,0.00013418618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038217113,0.00023309607,0.00025437336,0.00048265874,0.00022899894,0.0005453767,0.00017133907,0.00027708837,0.0037752683],"category_scores_gemma":[0.0017787861,0.00013160429,0.00022107422,0.0004287897,0.00018035357,0.00014075311,0.00014246933,0.0003459164,0.0002740337],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009993352,0.00014731222,0.9499237,0.000073885916,0.000081674814,0.0007338655,0.00019007939,0.0002177202,0.03274787,0.00013188142,0.0003248622,0.014427687],"study_design_scores_gemma":[0.00001400571,0.00042815413,0.98853827,0.000011683654,0.000062960135,0.0030673011,0.00015736617,0.0004025805,0.0064937267,0.00014952451,0.000667331,0.0000071241425],"about_ca_topic_score_codex":0.0015429144,"about_ca_topic_score_gemma":0.0007800798,"teacher_disagreement_score":0.0037752683,"about_ca_system_score_codex":0.0002637292,"about_ca_system_score_gemma":0.00016539283,"threshold_uncertainty_score":0.012629509},"labels":[],"label_agreement":null},{"id":"W4412938500","doi":"10.1172/jci195258","title":"Integrin α4β7 as a predictor of HIV acquisition: one thread in a complex tapestry","year":2025,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Human immunodeficiency virus (HIV); Thread (computing); Integrin; Computational biology; Medicine; Biology; Virology; Computer science; Internal medicine; Receptor; Programming language","score_opus":0.11010917078388846,"score_gpt":0.38687380047833647,"score_spread":0.27676462969444804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412938500","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009624692,0.0106887845,0.0003879118,0.96514446,0.01140337,0.000010647071,0.000079532314,0.000036175967,0.002624504],"genre_scores_gemma":[0.16632196,0.021087674,0.0023813113,0.58300567,0.22105597,0.000056927434,0.00016582501,0.000056002224,0.005868677],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983902,0.0006657388,0.00021328071,0.00025795307,0.0003434482,0.00012932417],"domain_scores_gemma":[0.99063885,0.006080433,0.00042430026,0.0003844716,0.001830117,0.00064182153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030413216,0.00035152354,0.0009459723,0.00071642076,0.001276789,0.0019643884,0.00095624925,0.0074400823,0.0020897912],"category_scores_gemma":[0.013093244,0.0002485638,0.00042171395,0.0005778086,0.0012886549,0.0021063888,0.00058853306,0.007753303,0.001733335],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000826807,0.00024157576,0.10876185,0.00042692598,0.00017593005,0.012430655,0.0007103592,0.00028155342,0.0027366902,0.006097051,0.68819034,0.1791202],"study_design_scores_gemma":[0.0007246,0.0009407941,0.116794884,0.0030607015,0.0006729403,0.06166132,0.0056945737,0.011009225,0.0038422504,0.09068017,0.70454544,0.00037316643],"about_ca_topic_score_codex":0.002044303,"about_ca_topic_score_gemma":0.0025304817,"teacher_disagreement_score":0.0074400823,"about_ca_system_score_codex":0.0010774513,"about_ca_system_score_gemma":0.0009632055,"threshold_uncertainty_score":0.016084254},"labels":[],"label_agreement":null},{"id":"W4413315181","doi":"10.1172/jci190989","title":"A distinct mechanism of epigenetic reprogramming silences PAX2 and initiates endometrial carcinogenesis","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"L'Alliance Boviteq","funders":"National Cancer Institute; Japan Society for the Promotion of Science; National Institutes of Health; Cancer Prevention and Research Institute of Texas; Mary Kay Foundation","keywords":"Reprogramming; Epigenetics; Carcinogenesis; Mechanism (biology); Epigenesis; Biology; Cell biology; DNA methylation; Cancer research; Endometrial cancer; Genetics; Cancer; Gene; Gene expression; Physics","score_opus":0.03955910198113187,"score_gpt":0.34936482612908704,"score_spread":0.30980572414795515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413315181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9572259,0.006505619,0.028575178,0.0002973127,0.00007673969,0.000052378713,0.000513401,0.00027163315,0.006481801],"genre_scores_gemma":[0.9934476,0.0013782324,0.002747346,0.00007552892,0.000014603825,0.000024068888,0.00029685744,0.000018302457,0.0019975773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986744,0.000014078184,0.0000072129737,0.000038569313,0.000045979876,0.000026601545],"domain_scores_gemma":[0.9999324,0.000009713378,0.000019403398,0.000016270134,0.000009544882,0.000012615271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015211989,0.00019678628,0.00020444626,0.00023906288,0.00019186805,0.0003799115,0.00020698813,0.00025407452,0.0009830812],"category_scores_gemma":[0.0001927934,0.0001641742,0.00026378955,0.00017515669,0.0003019627,0.00029227426,0.00046117682,0.0003741302,0.00024539474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000774936,0.0000062822064,0.0017674749,0.000041488394,0.000010575803,0.00015881409,0.00003962151,0.00013366729,0.989349,0.0013640219,0.000052658692,0.0069988277],"study_design_scores_gemma":[0.000018435241,0.00019605816,0.022619555,0.000016591695,0.000031429645,0.001652764,0.00012184946,0.0022000945,0.95918345,0.0009570907,0.012987711,0.000014930681],"about_ca_topic_score_codex":0.00033077653,"about_ca_topic_score_gemma":0.0006427517,"teacher_disagreement_score":0.0009830812,"about_ca_system_score_codex":0.00020310041,"about_ca_system_score_gemma":0.00022186186,"threshold_uncertainty_score":0.0032887459},"labels":[],"label_agreement":null},{"id":"W4414081406","doi":"10.1172/jci184172","title":"Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesis","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bishop's University","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Novo Nordisk Fonden; Cancer Research Coordinating Committee; U.S. Department of Veterans Affairs","keywords":"Heparan sulfate; Carcinogenesis; Metastasis; Pancreatic cancer; Pancreatic Intraepithelial Neoplasia; Adenocarcinoma; Thrombin; Inflammation","score_opus":0.036723684294950015,"score_gpt":0.3616242026377325,"score_spread":0.32490051834278244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414081406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924068,0.0032277715,0.001692371,0.000118210046,0.000035213656,0.000027439077,0.0002236267,0.00013817241,0.002130264],"genre_scores_gemma":[0.9933897,0.0013091168,0.0008529183,0.000045909186,0.000009710085,0.000022603383,0.0004220599,0.000016553113,0.003931445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998609,0.000032571243,0.000011743877,0.000017725437,0.000042263546,0.00003463991],"domain_scores_gemma":[0.9999124,0.000009723545,0.000021808046,0.000011772404,0.00000900887,0.000035300596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011867351,0.0002801252,0.00026232935,0.0002467287,0.000114113565,0.00023122958,0.00013862106,0.00020711722,0.00087273173],"category_scores_gemma":[0.00010315326,0.000100296806,0.00012841493,0.00022660285,0.00019250227,0.000103159364,0.00014468927,0.00044398976,0.00023315407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026219783,0.000082395156,0.00041534772,0.000030693303,0.000007904116,0.00008671132,0.000008617936,0.000043933265,0.995526,0.000093418486,0.000085645865,0.0033571084],"study_design_scores_gemma":[0.000058286874,0.0010713162,0.012810017,0.000006851096,0.000030965224,0.00057028857,0.000033935463,0.0011455627,0.9769449,0.00007650377,0.0072476678,0.0000037869854],"about_ca_topic_score_codex":0.00050919584,"about_ca_topic_score_gemma":0.0008567533,"teacher_disagreement_score":0.00087273173,"about_ca_system_score_codex":0.00017753612,"about_ca_system_score_gemma":0.00023675285,"threshold_uncertainty_score":0.0029195547},"labels":[],"label_agreement":null},{"id":"W4414116050","doi":"10.1172/jci192052","title":"Molnupiravir clinical trial simulation suggests that polymerase chain reaction underestimates antiviral potency against SARS-CoV-2","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Potency; In vivo; Antiviral drug; In vitro; Clinical trial; Drug; Viral load; Virus","score_opus":0.23832213201962815,"score_gpt":0.5061695802385222,"score_spread":0.26784744821889406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414116050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82751435,0.0015069853,0.1561888,0.0023410597,0.00015162422,0.0007717934,0.001844301,0.00040910442,0.009271972],"genre_scores_gemma":[0.9833776,0.0002501376,0.013973826,0.0005497585,0.000012511782,0.00034375885,0.0004387287,0.000025206999,0.0010284779],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9952808,0.0034119992,0.000209797,0.0004490595,0.00041307838,0.0002352624],"domain_scores_gemma":[0.973943,0.021710329,0.0020127336,0.0009873852,0.0010608272,0.00028565773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.011477061,0.0005903766,0.0012151315,0.00032526895,0.00023448723,0.0014655823,0.0010354848,0.0009231476,0.0014836454],"category_scores_gemma":[0.026773887,0.0004912384,0.0010018154,0.00039108042,0.0005442986,0.0009148891,0.00031197985,0.0011661585,0.0002544466],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008913849,0.00014025907,0.01672738,0.00017876354,0.0002559034,0.00016588203,0.000092194656,0.96429837,0.0030939768,0.0045213075,0.0010317286,0.008602823],"study_design_scores_gemma":[0.00033290964,0.0011573139,0.0041364827,0.000050843788,0.00018072626,0.00014076171,0.00003742092,0.98289835,0.0037424667,0.0056357733,0.0016560297,0.00003097815],"about_ca_topic_score_codex":0.0053908206,"about_ca_topic_score_gemma":0.005040239,"teacher_disagreement_score":0.011477061,"about_ca_system_score_codex":0.0016799835,"about_ca_system_score_gemma":0.0025512995,"threshold_uncertainty_score":0.060697258},"labels":[],"label_agreement":null},{"id":"W4414121550","doi":"10.1172/jci169395","title":"Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease models","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Japan Society for the Promotion of Science; Horizon 2020 Framework Programme; Institute of Genetics; National Institutes of Health; Institut Universitaire de France; Centre National de la Recherche Scientifique; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Fondation ARC pour la Recherche sur le Cancer; Agence Nationale de la Recherche; National Institute of Allergy and Infectious Diseases; Cancer Prevention and Research Institute of Texas; Universität Heidelberg; European Commission; Japan Agency for Medical Research and Development; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale; Deutsche Forschungsgemeinschaft; Universität Basel; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Hepatocellular carcinoma; Steatohepatitis; Liver cancer; Fatty liver; Transcriptome; Liver disease; AMPK; Cancer","score_opus":0.08694456766440774,"score_gpt":0.37601472462426483,"score_spread":0.2890701569598571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414121550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903651,0.00072167243,0.007550897,0.00013030086,0.000041753196,0.000052100742,0.00041600454,0.0002273218,0.0004948879],"genre_scores_gemma":[0.992717,0.0005108078,0.004952898,0.00005323602,0.000005900093,0.00006687566,0.0007939951,0.000023843979,0.00087540055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987185,0.00002922736,0.0000118107455,0.00003219434,0.000024712239,0.000030279396],"domain_scores_gemma":[0.9999081,0.000013598351,0.000029339737,0.000012056906,0.000007378665,0.00002951072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035831536,0.00036081648,0.0004888922,0.00024132412,0.00014479418,0.0003003966,0.00021314612,0.00021539236,0.00089442305],"category_scores_gemma":[0.00017472183,0.0001422877,0.00037065134,0.00013925102,0.00017138956,0.00016595,0.00030761724,0.00057879824,0.00010086585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018784361,0.00049724494,0.0023767836,0.00011807044,0.000066655106,0.00008212765,0.000022045246,0.0013395298,0.9859532,0.00025790502,0.0001890312,0.007219034],"study_design_scores_gemma":[0.0002455862,0.0051257494,0.011815538,0.000016058842,0.00015775648,0.00029032104,0.00006212111,0.02046485,0.9581218,0.00033745405,0.0033457808,0.000017103468],"about_ca_topic_score_codex":0.00040119851,"about_ca_topic_score_gemma":0.0009942562,"teacher_disagreement_score":0.00089442305,"about_ca_system_score_codex":0.00018802156,"about_ca_system_score_gemma":0.00027737435,"threshold_uncertainty_score":0.0029921532},"labels":[],"label_agreement":null},{"id":"W4414195829","doi":"10.1172/jci186420","title":"MASH: the nexus of metabolism, inflammation, and fibrosis","year":2025,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; HLS Therapeutics; Diabetes Canada; Eli Lilly and Company","keywords":"Hepatocyte; Steatohepatitis; Fibrosis; Fatty liver; Adipose tissue; Hepatic stellate cell; Lipid metabolism; Lipotoxicity; Inflammation; Crosstalk","score_opus":0.11797412536241282,"score_gpt":0.43331478705016596,"score_spread":0.31534066168775315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414195829","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011476615,0.9977355,0.00015837955,0.00037873266,0.0002791083,0.0000052692885,0.00002356712,0.000013761834,0.001290873],"genre_scores_gemma":[0.000671682,0.99782526,0.00023171383,0.00023955191,0.00017382158,0.0000068270883,0.00003807946,0.0000018137696,0.0008112848],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998573,0.000024840701,0.00001962619,0.000021778267,0.000059078102,0.00001730364],"domain_scores_gemma":[0.9998387,0.000057415455,0.000023941513,0.0000052487953,0.000050294126,0.000024305507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037394426,0.00076119084,0.0011186054,0.0016738431,0.00027648167,0.0010616431,0.0006631675,0.00088589144,0.0034552093],"category_scores_gemma":[0.00043704125,0.00021758238,0.00039048452,0.0016552812,0.0003945739,0.0011610056,0.00069801346,0.0019371905,0.0025004868],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000862555,0.00005589431,0.00013414271,0.013091258,0.00008256635,0.00016280613,0.000051235675,0.00023809755,0.0024272208,0.0046506226,0.029906906,0.9491131],"study_design_scores_gemma":[0.000013505442,0.00007347472,0.0006118559,0.0024389531,0.00006012769,0.0008582352,0.000044056604,0.00006648157,0.00039800577,0.0022139538,0.9932081,0.000013264043],"about_ca_topic_score_codex":0.0008036485,"about_ca_topic_score_gemma":0.0016415751,"teacher_disagreement_score":0.0034552093,"about_ca_system_score_codex":0.0006012276,"about_ca_system_score_gemma":0.0011118159,"threshold_uncertainty_score":0.01155889},"labels":[],"label_agreement":null},{"id":"W4414239244","doi":"10.1172/jci178089","title":"A liver-infiltrating CD4+ Tfh1 cell response predicts HCV control, hepatitis, and seroconversion during acute infection","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hepatitis C virus research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Emory University","keywords":"Hepatitis C virus; Virus; Seroconversion; Immune system; T cell; Immunity; Hepatitis B virus; Cell","score_opus":0.04385689594728317,"score_gpt":0.38354073303809316,"score_spread":0.33968383709081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414239244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993882,0.0001740384,0.00010880549,0.0000057154098,0.0000022976749,0.000004147178,0.000071513205,0.0000086783675,0.00023664505],"genre_scores_gemma":[0.9994935,0.000059616596,0.0001032232,0.000006380011,0.000003808705,0.000004333464,0.00010729913,0.0000019327256,0.00021994252],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99994576,0.000008944587,0.0000043331265,0.000016660864,0.0000074808054,0.0000168383],"domain_scores_gemma":[0.999796,0.000028535947,0.00007484198,0.000011656863,0.000012540289,0.00007646453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014185946,0.00017257486,0.00016374083,0.00037412412,0.0001204007,0.00027472118,0.00005357301,0.00018980136,0.0014444545],"category_scores_gemma":[0.00029472803,0.0001320858,0.00007644827,0.00014345931,0.00017316562,0.000121703444,0.00009689442,0.00030857068,0.0001874636],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002899467,0.00012040866,0.6980313,0.00006437787,0.000033633372,0.00026995514,0.00018653792,0.00030037228,0.28900906,0.00006813301,0.00017857416,0.008838132],"study_design_scores_gemma":[0.000011832501,0.0003777362,0.9889902,0.000006368429,0.00002070325,0.0005812636,0.00010355189,0.0005653752,0.0089955,0.000030306426,0.0003125479,0.0000046117107],"about_ca_topic_score_codex":0.000605849,"about_ca_topic_score_gemma":0.00081141037,"teacher_disagreement_score":0.0014444545,"about_ca_system_score_codex":0.00013029917,"about_ca_system_score_gemma":0.00006118504,"threshold_uncertainty_score":0.004832208},"labels":[],"label_agreement":null},{"id":"W4414313132","doi":"10.1172/jci182100","title":"PTBP1 variants displaying altered nucleocytoplasmic distribution are responsible for a neurodevelopmental disorder with skeletal dysplasia","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Institute of Genetics; Western University; University of Toronto; London Health Sciences Centre","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Ministero della Salute; Agence Nationale de la Recherche; European Commission","keywords":"Missense mutation; RNA splicing; Ribonucleoprotein; RNA-binding protein; Cell nucleus; RNA; Transcriptome; Exon; Heterogeneous nuclear ribonucleoprotein; Germline","score_opus":0.0390677594364968,"score_gpt":0.3747278686516319,"score_spread":0.33566010921513506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414313132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99553764,0.00088594476,0.0016208526,0.00009048562,0.000016871494,0.000025264078,0.0004448885,0.00006096641,0.0013172124],"genre_scores_gemma":[0.9979603,0.00029596765,0.00069777196,0.00003754322,0.000016948492,0.0000097505945,0.00029464485,0.00001477279,0.00067223853],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9997745,0.000034779183,0.00002795903,0.000078892954,0.000054263917,0.00002956173],"domain_scores_gemma":[0.9998221,0.000047647976,0.00006734004,0.000010282314,0.000018125986,0.000034522152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001588027,0.0011307757,0.00033701098,0.0009764754,0.0005100464,0.00026966215,0.00029507498,0.0006000712,0.0026579304],"category_scores_gemma":[0.0006236278,0.0001723923,0.00018713373,0.0005428877,0.0004127228,0.00012363201,0.0003081491,0.00031146512,0.00039311848],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019307705,0.00019492755,0.19736283,0.00033298455,0.00022475343,0.23453653,0.00076023786,0.0005866743,0.5346474,0.0009840804,0.0012374024,0.02720138],"study_design_scores_gemma":[0.00008765758,0.00042232018,0.46497545,0.00010565599,0.00029139413,0.46692258,0.00032586063,0.0016814983,0.059799302,0.00051472324,0.0048411884,0.00003224281],"about_ca_topic_score_codex":0.0009733207,"about_ca_topic_score_gemma":0.0009149204,"teacher_disagreement_score":0.0026579304,"about_ca_system_score_codex":0.0001924173,"about_ca_system_score_gemma":0.00017661913,"threshold_uncertainty_score":0.008891642},"labels":[],"label_agreement":null},{"id":"W4414462678","doi":"10.1172/jci180927","title":"USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"PTEN; PI3K/AKT/mTOR pathway; Suppressor; Downregulation and upregulation; Phosphatase; Phosphorylation; Breast cancer; Mutant","score_opus":0.025899021860336227,"score_gpt":0.35755280271690343,"score_spread":0.3316537808565672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414462678","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98641974,0.0029737959,0.0030439997,0.00051444664,0.00009755654,0.0000992257,0.0012170885,0.0003613431,0.0052727656],"genre_scores_gemma":[0.9925397,0.0014581465,0.0016340701,0.00010138033,0.000011741054,0.0000508328,0.00094695145,0.000032984295,0.0032242376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998086,0.000029240955,0.000019622577,0.000029444896,0.00006826872,0.000044721404],"domain_scores_gemma":[0.999913,0.000013915384,0.000023076183,0.000010961547,0.0000080179725,0.000031078886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022362395,0.00031291638,0.00027704582,0.00028480156,0.0001541467,0.0004515697,0.000203119,0.00029633826,0.0012562458],"category_scores_gemma":[0.00011030246,0.00018091059,0.00025148754,0.00021384962,0.00031498674,0.0001499586,0.00017856169,0.0010108174,0.0004809723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015099306,0.00014359572,0.0003643214,0.000045511777,0.000010247453,0.00012349413,0.000012902606,0.00013878754,0.994177,0.00030923582,0.000339829,0.00418413],"study_design_scores_gemma":[0.000075626915,0.0007550733,0.007025544,0.000008530892,0.000031755713,0.000869698,0.000036425365,0.0028607715,0.98062485,0.00012980688,0.0075736344,0.000008229271],"about_ca_topic_score_codex":0.0009180348,"about_ca_topic_score_gemma":0.0016887784,"teacher_disagreement_score":0.0012562458,"about_ca_system_score_codex":0.0005060095,"about_ca_system_score_gemma":0.00039770227,"threshold_uncertainty_score":0.0042026043},"labels":[],"label_agreement":null},{"id":"W4414533051","doi":"10.1172/jci200201","title":"An open letter to the NIH: value and costs in publishing","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Health and Medical Research Impacts","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Journal of Communication (Canada)","funders":"","keywords":"Value (mathematics); Publishing; MEDLINE; Value of life","score_opus":0.3763234220812968,"score_gpt":0.5765139706756192,"score_spread":0.20019054859432234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414533051","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":"evaluation","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":"evaluation","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000108719934,0.00070009613,0.000058487636,0.96834296,0.029278535,0.0000051464085,0.000017584283,0.000017186248,0.001471264],"genre_scores_gemma":[0.0029932514,0.0009137969,0.00040474036,0.92379963,0.06586804,0.000018626864,0.000027229806,0.0000481671,0.005926553],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9518453,0.011576903,0.007218076,0.0028954654,0.021476412,0.0049877684],"domain_scores_gemma":[0.7125306,0.16051647,0.013957487,0.010147833,0.06928611,0.033561513],"candidate_categories":["metaresearch","scholarly_communication"],"consensus_categories":[],"category_scores_codex":[0.02948915,0.001094558,0.0023707016,0.0022826206,0.008673829,0.017756613,0.0050584716,0.097865336,0.020618971],"category_scores_gemma":[0.23391747,0.001517843,0.0023395892,0.002713785,0.012053285,0.014551147,0.006289321,0.07093227,0.010677934],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006001986,0.000026217707,0.00024742226,0.00006304038,0.000015580406,0.00026488394,0.00011777975,0.000025105017,0.000118167576,0.004709205,0.98693186,0.007420764],"study_design_scores_gemma":[0.000102922655,0.000051752566,0.0008544921,0.0005863216,0.000043387277,0.0006945713,0.00082278665,0.00024106908,0.00028235698,0.011381705,0.9848112,0.00012743915],"about_ca_topic_score_codex":0.007110392,"about_ca_topic_score_gemma":0.010122759,"teacher_disagreement_score":0.98224336,"about_ca_system_score_codex":0.0076630386,"about_ca_system_score_gemma":0.022497507,"threshold_uncertainty_score":0.15595537},"labels":[],"label_agreement":null},{"id":"W4414632805","doi":"10.1172/jci197100","title":"Clonal hematopoiesis driven by Dnmt3a mutations promotes metabolic disease development in mice","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Edward P. Evans Foundation","keywords":"Haematopoiesis; Mutation; Disease; Metabolic pathway; Metabolic disease; Metabolism","score_opus":0.031565004920227464,"score_gpt":0.350675772906966,"score_spread":0.31911076798673854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414632805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97348255,0.004137146,0.010047969,0.00093410065,0.00012924643,0.0001885042,0.004206858,0.00075237267,0.0061212657],"genre_scores_gemma":[0.97718334,0.0035109718,0.008035159,0.0003886512,0.00006145175,0.00029167792,0.0019589793,0.00017715422,0.008392537],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994861,0.00012208572,0.0000549868,0.00012029479,0.00011739414,0.0000992265],"domain_scores_gemma":[0.9995167,0.00007117681,0.00017041211,0.000049207192,0.000024351197,0.00016817011],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006247834,0.00058408343,0.00034144867,0.0014442194,0.00033477292,0.0005795717,0.00050265214,0.00094220246,0.004850917],"category_scores_gemma":[0.00030279928,0.00046213376,0.0005120836,0.00034987528,0.00060125144,0.00040025474,0.0005232577,0.0018203702,0.0008697763],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007808215,0.00043054056,0.0014270789,0.00013448908,0.000040017138,0.00034925557,0.000077777986,0.00022223253,0.98922837,0.0014823141,0.0005316938,0.0052955276],"study_design_scores_gemma":[0.00074629125,0.0038316133,0.03683885,0.0003302827,0.0002934494,0.004508875,0.00023955487,0.008167079,0.91639143,0.0018646687,0.026726004,0.000061841485],"about_ca_topic_score_codex":0.00064228167,"about_ca_topic_score_gemma":0.0013489646,"teacher_disagreement_score":0.004850917,"about_ca_system_score_codex":0.00052937906,"about_ca_system_score_gemma":0.0003885931,"threshold_uncertainty_score":0.01622796},"labels":[],"label_agreement":null},{"id":"W4414644657","doi":"10.1172/jci188620","title":"Circadian rhythmicity and biopsychosocial characteristics influence opioid use in chronic low back pain","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Dietary Effects on Health","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université de Montréal; Queen's University; McMaster University; Kingston Health Sciences Centre; McGill University Health Centre; Centre Hospitalier de l’Université de Montréal","funders":"Strategy for Patient-Oriented Research; Canadian Institutes of Health Research","keywords":"Biopsychosocial model; Circadian rhythm; Chronic pain; Opioid; Low back pain; Population; Pain assessment","score_opus":0.05370515909705274,"score_gpt":0.38737860576033145,"score_spread":0.3336734466632787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414644657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99466443,0.0030178057,0.0007366127,0.00022891277,0.0000211203,0.00003628204,0.00041414058,0.000008930591,0.00087169296],"genre_scores_gemma":[0.9982843,0.00083756744,0.00031553474,0.00008529588,0.00002101264,0.000017986387,0.00018575351,0.000003851454,0.00024868542],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.999739,0.00008681045,0.000016738793,0.000055437165,0.000047619946,0.000054437387],"domain_scores_gemma":[0.99927276,0.0001441617,0.00036116937,0.000030039562,0.00011000535,0.00008192744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003925674,0.00018790545,0.00023777988,0.00029528886,0.00026146587,0.0005193036,0.0001330479,0.00018562816,0.0015477438],"category_scores_gemma":[0.0015362398,0.00009770655,0.00020833194,0.00037370692,0.00020225724,0.00020061071,0.00033316217,0.00028294546,0.000119471835],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005727991,0.00011288748,0.9568895,0.00018775818,0.00015218178,0.00013140813,0.0004360927,0.00023899121,0.0075456565,0.00012649574,0.00038617587,0.03322014],"study_design_scores_gemma":[0.000001941282,0.000048188922,0.99944776,0.00001090389,0.000011467702,0.00004563802,0.00007334582,0.000107393724,0.00006769524,0.00003848204,0.00014461497,0.000002463089],"about_ca_topic_score_codex":0.005266715,"about_ca_topic_score_gemma":0.011692508,"teacher_disagreement_score":0.005266715,"about_ca_system_score_codex":0.00030107985,"about_ca_system_score_gemma":0.0003229136,"threshold_uncertainty_score":0.010472119},"labels":[],"label_agreement":null},{"id":"W4414681896","doi":"10.1172/jci195267","title":"Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Alberta","funders":"Canadian Institutes of Health Research; National Human Genome Research Institute; University of California, San Diego; Vetenskapsrådet; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Alberta Innovates; Knut och Alice Wallenbergs Stiftelse; Human Islet Research Network","keywords":"Islet; Immune system; Transcriptome; Downregulation and upregulation; mTORC1; Phenotype; Cell type; Lysosome; Major histocompatibility complex; Cell","score_opus":0.04156627617723751,"score_gpt":0.3318410158633541,"score_spread":0.2902747396861166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414681896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952874,0.0011380127,0.0024016993,0.000073427924,0.000013398055,0.000010682125,0.0006073055,0.000049818562,0.00041818983],"genre_scores_gemma":[0.9947902,0.0011528765,0.0027833283,0.00014970155,0.000018716093,0.000023143735,0.0007502913,0.000024281206,0.00030749824],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999846,0.000028657754,0.000012542879,0.000048585298,0.000041850646,0.000022405866],"domain_scores_gemma":[0.99986815,0.000029230985,0.000053564516,0.000015994392,0.000010086402,0.000022897235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031510627,0.00037475076,0.00036806223,0.00044673446,0.00019196466,0.00053511525,0.00009595416,0.00019515783,0.0010707098],"category_scores_gemma":[0.0003552435,0.00011891808,0.00023350534,0.000549672,0.00026444677,0.00018559488,0.0003159106,0.00054833025,0.00019282318],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017495082,0.00016688184,0.06134341,0.00019825783,0.00012646845,0.00035451128,0.0001270178,0.0011640387,0.9042105,0.00018997189,0.00029267595,0.030076746],"study_design_scores_gemma":[0.000040262385,0.0010640518,0.8429164,0.00006063313,0.00018140263,0.0020622204,0.00035696715,0.005208261,0.14437518,0.001231428,0.0024616069,0.000041653904],"about_ca_topic_score_codex":0.00023067469,"about_ca_topic_score_gemma":0.00036077743,"teacher_disagreement_score":0.0010707098,"about_ca_system_score_codex":0.00014886659,"about_ca_system_score_gemma":0.00014406124,"threshold_uncertainty_score":0.0035818815},"labels":[],"label_agreement":null},{"id":"W4414896765","doi":"10.1172/jci197583","title":"The cell-type–specific genetic architecture of chronic pain in brain and dorsal root ganglia","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse; National Institute of Arthritis and Musculoskeletal and Skin Diseases; VISN 4 Mental Illness Research, Education, and Clinical Center; NIH Clinical Center; National Institutes of Health; National Institute on Alcohol Abuse and Alcoholism; Eli Lilly and Company; U.S. Department of Veterans Affairs","keywords":"Glutamatergic; Chronic pain; Genome-wide association study; Context (archaeology); GABAergic; Axon; Dorsal root ganglion; Spinal cord","score_opus":0.05247333241603073,"score_gpt":0.34214829587093687,"score_spread":0.2896749634549061,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414896765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832373,0.0022283064,0.00891848,0.00024034023,0.000036881378,0.000026766678,0.0030552465,0.000124609,0.0021320262],"genre_scores_gemma":[0.9938267,0.00072413275,0.0029735826,0.000164231,0.000015934058,0.000033069766,0.0015592744,0.00004377082,0.0006592691],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996012,0.00004975669,0.00002551951,0.000197451,0.000074483374,0.000051662446],"domain_scores_gemma":[0.99975044,0.00006645155,0.000090598034,0.000041792642,0.000028085535,0.000022585682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025380575,0.00021842754,0.00031979542,0.00046074836,0.00018170531,0.00052153115,0.00022803961,0.00022656436,0.0018205122],"category_scores_gemma":[0.0006231504,0.00016819571,0.00032023384,0.00045155376,0.00030362574,0.00017386347,0.00037766332,0.0004175808,0.00019361077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005720929,0.000081471735,0.30732334,0.00046256382,0.0011586406,0.0011653121,0.00047475545,0.0017589657,0.6269466,0.0024783507,0.0013876101,0.056190204],"study_design_scores_gemma":[0.000018847346,0.00009128521,0.98289376,0.00005485736,0.00021697312,0.0011523432,0.00012352469,0.0016099074,0.01005491,0.001720262,0.002045513,0.000017815997],"about_ca_topic_score_codex":0.0038647766,"about_ca_topic_score_gemma":0.007997484,"teacher_disagreement_score":0.0038647766,"about_ca_system_score_codex":0.00025770158,"about_ca_system_score_gemma":0.0002693533,"threshold_uncertainty_score":0.007684529},"labels":[],"label_agreement":null},{"id":"W4414896868","doi":"10.1172/jci186287","title":"CDKL1 variants affecting ciliary formation predispose to thoracic aortic aneurysm and dissection","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Deutsche Forschungsgemeinschaft; Universitätsklinikum Hamburg-Eppendorf; Universität Hamburg; Deutsches Zentrum für Herz-Kreislaufforschung","keywords":"Cilium; Zebrafish; Gene knockdown; Aortic dissection; Gene; Pathogenesis; Protein kinase domain; Gene knockout; Exome sequencing","score_opus":0.029661927568382634,"score_gpt":0.36072825387499285,"score_spread":0.3310663263066102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414896868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99799794,0.00034106252,0.00048287617,0.000052815554,0.000010559384,0.0000124623375,0.00027086487,0.00001979573,0.00081144844],"genre_scores_gemma":[0.9992519,0.00010462764,0.00030250076,0.00002054388,0.000010448341,0.0000034744517,0.00010440776,0.0000058252854,0.00019618057],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997695,0.000034939116,0.000025532621,0.000090698915,0.000040107127,0.00003915489],"domain_scores_gemma":[0.9996817,0.00010731667,0.00010337565,0.000019322279,0.000016881406,0.000071370334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016963479,0.0007579788,0.0003423556,0.00089101936,0.0005665519,0.00031882312,0.0002219357,0.0005090645,0.0026458837],"category_scores_gemma":[0.00072744634,0.00022935576,0.00030851184,0.00049406156,0.00046401905,0.00012967607,0.00028267555,0.00043412452,0.0002463512],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023597167,0.00014093085,0.7625044,0.00010402555,0.0002202431,0.05567673,0.00048947486,0.0011072307,0.16333266,0.00077717897,0.0007474196,0.012540055],"study_design_scores_gemma":[0.000103601844,0.00022520346,0.89458716,0.000037624224,0.00021684867,0.08365077,0.0002700108,0.0022022193,0.01616519,0.0005651177,0.0019354643,0.00004081104],"about_ca_topic_score_codex":0.0021843247,"about_ca_topic_score_gemma":0.0023856938,"teacher_disagreement_score":0.0026458837,"about_ca_system_score_codex":0.00033944205,"about_ca_system_score_gemma":0.00017873137,"threshold_uncertainty_score":0.008851349},"labels":[],"label_agreement":null},{"id":"W4415166562","doi":"10.1172/jci184474","title":"Biallelic variants in ARHGAP19 cause a progressive inherited motor-predominant neuropathy","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"CIHR Skin Research Training Centre; Medical Research Council; National Institutes of Health; Fundação de Amparo à Pesquisa do Estado de São Paulo; Università degli Studi dell'Aquila; Deutsche Forschungsgemeinschaft; Medical Research Future Fund; Natural Sciences and Engineering Research Council of Canada; Muscular Dystrophy Association; NIHR Cambridge Biomedical Research Centre; European Commission; University College London; Wellcome Trust; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research","keywords":"Phenotype; Transcriptome; Gene; Drosophila melanogaster; In silico; Mutation; RHOA; Disease; Genetic heterogeneity; HEK 293 cells","score_opus":0.12367123634047684,"score_gpt":0.40510950172284893,"score_spread":0.2814382653823721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415166562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979225,0.0004133536,0.0008125707,0.000029232284,0.000006693222,0.000017224333,0.00022690251,0.00004452072,0.0005271382],"genre_scores_gemma":[0.9983885,0.00016794633,0.00077445555,0.00002656833,0.000010381679,0.0000054480656,0.00018610204,0.000008994325,0.00043154712],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999833,0.000019189118,0.000017367829,0.00007217848,0.00004222687,0.00001604813],"domain_scores_gemma":[0.9998987,0.000024179828,0.00003984242,0.000007928824,0.0000066370794,0.000022756258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011863458,0.0008818818,0.00026472402,0.0005125099,0.0003057524,0.00018929351,0.00019172247,0.00037773547,0.0015614332],"category_scores_gemma":[0.00029327496,0.00016072088,0.00020204061,0.00039676955,0.0002494027,0.00009142841,0.0002919178,0.00029017692,0.00026054986],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016242212,0.00027056583,0.18298604,0.0002289536,0.00059649645,0.08972009,0.0005088164,0.0009867077,0.68474126,0.0007554018,0.0010931937,0.036488213],"study_design_scores_gemma":[0.00016175497,0.0011379971,0.75594,0.000047341524,0.00041206586,0.18016529,0.00022461888,0.0027628029,0.054002956,0.00041029265,0.004691361,0.00004346938],"about_ca_topic_score_codex":0.00075448543,"about_ca_topic_score_gemma":0.0013853334,"teacher_disagreement_score":0.0015614332,"about_ca_system_score_codex":0.00015878875,"about_ca_system_score_gemma":0.000113926995,"threshold_uncertainty_score":0.0052235126},"labels":[],"label_agreement":null},{"id":"W4415855223","doi":"10.1172/jci194751","title":"Antiinflammatory actions of glucagon-like peptide-1–based therapies beyond metabolic benefits","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; Novo Nordisk; Amgen; Pfizer; Diabetes Canada; Eli Lilly and Company","keywords":"Inflammation; Clinical trial; Disease; Diabetes mellitus; Kidney disease; Type 2 diabetes; Kidney","score_opus":0.07156355982170079,"score_gpt":0.37243666879161813,"score_spread":0.30087310896991737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415855223","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027517988,0.98729867,0.0011335729,0.003839248,0.0005966458,0.000019008447,0.000045610588,0.000021599808,0.0042937584],"genre_scores_gemma":[0.021509163,0.9720997,0.0018498393,0.0020732793,0.0012690254,0.000032650183,0.000057480745,0.0000053861945,0.0011033989],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99968004,0.00010813385,0.000043367556,0.000034243018,0.00009760921,0.00003665739],"domain_scores_gemma":[0.9994112,0.00033727696,0.00008826199,0.000016323153,0.00011072181,0.000036211182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010305342,0.00043676863,0.0008488828,0.00064849964,0.0001827642,0.001220626,0.00035820503,0.00064337096,0.002791942],"category_scores_gemma":[0.0010886348,0.000117226344,0.0005029675,0.00034246268,0.0005859212,0.0012253999,0.00053797895,0.0021260837,0.0004763374],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006639905,0.00020466816,0.00049066957,0.0147988,0.00015181302,0.000602146,0.00021327919,0.00046563536,0.02274486,0.018856393,0.014066718,0.92674094],"study_design_scores_gemma":[0.00022552728,0.0018920104,0.004218529,0.009247444,0.00038897523,0.0033122764,0.00040769193,0.00063676364,0.011661537,0.021672128,0.9462635,0.00007361513],"about_ca_topic_score_codex":0.00030823637,"about_ca_topic_score_gemma":0.00090268103,"teacher_disagreement_score":0.002791942,"about_ca_system_score_codex":0.0003557015,"about_ca_system_score_gemma":0.0007455596,"threshold_uncertainty_score":0.009339988},"labels":[],"label_agreement":null},{"id":"W4416322306","doi":"10.1172/jci171634","title":"Clonal hematopoiesis activates procalcific pathways in macrophages and promotes aortic valve stenosis","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Dr. Rolf M. Schwiete Stiftung; Deutsche Forschungsgemeinschaft; NIH Office of the Director; Deutsches Zentrum für Herz-Kreislaufforschung; Burroughs Wellcome Fund","keywords":"Oncostatin M; Proinflammatory cytokine; Bone marrow; Pathogenesis; Paracrine signalling; Haematopoiesis; Aortic valve; Mesenchymal stem cell","score_opus":0.07587172196992743,"score_gpt":0.3965108049611365,"score_spread":0.3206390829912091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416322306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944482,0.004245127,0.00037195635,0.00016671953,0.000012151548,0.000008531161,0.0001348903,0.000017444609,0.00059497234],"genre_scores_gemma":[0.99847096,0.000773547,0.00020817282,0.00009756947,0.000023234596,0.000007273987,0.000128282,0.0000021571739,0.00028874024],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998055,0.00006794465,0.000013659378,0.00003805368,0.000041183175,0.000033527183],"domain_scores_gemma":[0.9997849,0.00004941671,0.00008721383,0.000024332052,0.000021117365,0.000033030574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034939364,0.00014207618,0.00020432739,0.00032564718,0.000106280495,0.00036633786,0.00010924356,0.00018249203,0.0006794504],"category_scores_gemma":[0.00045402432,0.00008985619,0.00024638526,0.00025985844,0.00014947008,0.00010590719,0.00022868998,0.0002914662,0.00007703363],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0063897595,0.0002195796,0.6419151,0.00082241074,0.00089666474,0.0018136442,0.0003172966,0.0008291124,0.23397753,0.0009854642,0.0021608786,0.10967262],"study_design_scores_gemma":[0.00024113272,0.0006286239,0.95558816,0.0001251381,0.000969087,0.0030863339,0.00028851302,0.0018911307,0.029438438,0.000920203,0.006809275,0.000013954926],"about_ca_topic_score_codex":0.00039569056,"about_ca_topic_score_gemma":0.0007751453,"teacher_disagreement_score":0.0006794504,"about_ca_system_score_codex":0.00014975613,"about_ca_system_score_gemma":0.00013244235,"threshold_uncertainty_score":0.0022730231},"labels":[],"label_agreement":null},{"id":"W4416322354","doi":"10.1172/jci195840","title":"EZH2 crosstalk with RNA methylation promotes prostate cancer progression through modulation of m6A autoregulation pathway","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Robert H. Lurie Comprehensive Cancer Center; National Cancer Institute; National Institutes of Health; Northwestern University; Elsa U. Pardee Foundation; American Association for Cancer Research; U.S. Department of Defense","keywords":"EZH2; Autoregulation; Prostate cancer; Methyltransferase; Translation (biology); microRNA; Gene knockdown; Transcription (linguistics); RNA; FOXA1","score_opus":0.043770044897244294,"score_gpt":0.39647151950525306,"score_spread":0.35270147460800877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416322354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98877966,0.005689265,0.002130751,0.0002807012,0.0000645417,0.000024716634,0.0002729941,0.00020546354,0.0025518534],"genre_scores_gemma":[0.99693054,0.0009939556,0.00036195043,0.000058195703,0.000012824733,0.000016736562,0.00013061955,0.000006692164,0.0014885304],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999899,0.000016764958,0.000005814783,0.000022492262,0.000022511877,0.000033302524],"domain_scores_gemma":[0.9999671,0.0000028636514,0.000008311591,0.0000026921275,0.0000042937118,0.000014702325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010035344,0.0002616841,0.00023901706,0.00014231999,0.0001450274,0.00021698738,0.00011566572,0.00017554878,0.001229547],"category_scores_gemma":[0.00008819857,0.00010196259,0.0002013264,0.00008140886,0.00014635311,0.00015150612,0.00024787534,0.0004270833,0.00019645986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036236606,0.000037734586,0.0009285019,0.00009044463,0.000019860965,0.00010472947,0.000023073817,0.00015249998,0.9934103,0.00023589202,0.00026039523,0.004374222],"study_design_scores_gemma":[0.00005406072,0.00060443283,0.023904918,0.000008870447,0.000057675963,0.00031927525,0.000065763445,0.0022157235,0.9645845,0.00017630574,0.0079966895,0.000011638331],"about_ca_topic_score_codex":0.00044018563,"about_ca_topic_score_gemma":0.0011996215,"teacher_disagreement_score":0.001229547,"about_ca_system_score_codex":0.00018397708,"about_ca_system_score_gemma":0.00020670472,"threshold_uncertainty_score":0.004113257},"labels":[],"label_agreement":null},{"id":"W4416573201","doi":"10.1172/jci184514","title":"P selectin promotes SARS-CoV-2 interactions with platelets and the endothelium","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research","keywords":"Platelet; P-selectin; Platelet activation; Innate immune system; Receptor; Selectin; Gene; Endothelium; L-selectin","score_opus":0.11311513616429007,"score_gpt":0.49042964422658214,"score_spread":0.37731450806229205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416573201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99692684,0.0005834183,0.0010738239,0.0001070044,0.0000116648425,0.000012999094,0.00006609516,0.000026159289,0.0011919498],"genre_scores_gemma":[0.9974771,0.00021570275,0.0007648202,0.000057767204,0.000008898481,0.000011209668,0.00011670209,0.000006036301,0.0013417541],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998512,0.000041697764,0.000007177135,0.000020846326,0.000038035352,0.000041085255],"domain_scores_gemma":[0.9999236,0.000017923177,0.00002207018,0.0000070440838,0.000009284333,0.000020081505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012144225,0.0001437618,0.00014982097,0.000118820586,0.00012368,0.00027530562,0.000059565555,0.00017503265,0.0013008863],"category_scores_gemma":[0.00014211345,0.00008687909,0.00012916788,0.000057021287,0.00012996067,0.00010644836,0.00012216026,0.0004153245,0.00021002082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119722776,0.000030084226,0.00032004266,0.000011270757,0.000002747031,0.000070393275,0.000009723321,0.00004186723,0.9985096,0.00007730105,0.000049296286,0.00075791567],"study_design_scores_gemma":[0.000032786214,0.00079388515,0.02198063,0.000007466371,0.000015236118,0.0005063436,0.00005046527,0.0024417355,0.97134024,0.00010845779,0.00271799,0.000004717454],"about_ca_topic_score_codex":0.00026986224,"about_ca_topic_score_gemma":0.0003783406,"teacher_disagreement_score":0.0013008863,"about_ca_system_score_codex":0.00017015335,"about_ca_system_score_gemma":0.00015505924,"threshold_uncertainty_score":0.0043519735},"labels":[],"label_agreement":null},{"id":"W4416645852","doi":"10.1172/jci189830","title":"Functional consequence of pathogenic GABRA3 variants determines whether X-linked inheritance is dominant or recessive","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; Newborn Screening Ontario; Children's Hospital of Eastern Ontario","funders":"National Health and Medical Research Council; Lundbeckfonden; National Institutes of Health; H. Lundbeck A/S; Medical Research Council; Stiftung Michael","keywords":"Epilepsy; Inheritance (genetic algorithm); Epilepsy syndromes; CLARITY; Multifactorial Inheritance; Generalized epilepsy; Gene; Intellectual disability; Penetrance","score_opus":0.05954585628538313,"score_gpt":0.35674250318806205,"score_spread":0.29719664690267894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416645852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98732156,0.0035923263,0.0056998446,0.00048171968,0.00004548021,0.000017825838,0.0009078831,0.00018990686,0.0017435453],"genre_scores_gemma":[0.9949443,0.0014441196,0.0023904198,0.00022896625,0.000026916714,0.000010499953,0.00036244417,0.00008404165,0.0005083951],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9995421,0.00009621341,0.000052286687,0.00016091338,0.00009318603,0.00005525493],"domain_scores_gemma":[0.99950445,0.00019979097,0.00015517414,0.00006271116,0.000040064388,0.000037895246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006530891,0.00085001474,0.00042354545,0.0006066395,0.00028948468,0.00063857884,0.0002839356,0.00050901267,0.0016313865],"category_scores_gemma":[0.0012118316,0.00017131963,0.0004200447,0.00031853266,0.0005170223,0.00024661206,0.00050676026,0.0005101738,0.0003538938],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00082602754,0.00004563054,0.22568665,0.00029811345,0.00060373964,0.012394574,0.000847385,0.0009382886,0.70518184,0.0030719945,0.0009840733,0.049121734],"study_design_scores_gemma":[0.0001209108,0.00055620604,0.69492596,0.00045981145,0.0013211287,0.07124505,0.000953857,0.0052423547,0.20078567,0.006326678,0.017948192,0.00011419962],"about_ca_topic_score_codex":0.0017607606,"about_ca_topic_score_gemma":0.0026257907,"teacher_disagreement_score":0.0017607606,"about_ca_system_score_codex":0.00021974437,"about_ca_system_score_gemma":0.0002606679,"threshold_uncertainty_score":0.0054575205},"labels":[],"label_agreement":null},{"id":"W4416665762","doi":"10.1172/jci181943","title":"Loss of FBXO11 establishes a stem cell program in acute myeloid leukemia by dysregulating LONP1","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Spinal Cord Injury BC","funders":"Terry Fox Research Institute; Canadian Institutes of Health Research; Killam Trusts","keywords":"Ubiquitin ligase; Myeloid leukemia; Stem cell; Haematopoiesis; Progenitor cell; Myeloid; Mitochondrion; Hematopoietic stem cell","score_opus":0.04826515329223378,"score_gpt":0.38827299562937206,"score_spread":0.34000784233713827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416665762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987081,0.0003134123,0.00052109687,0.000024700783,0.0000034256984,0.000009300511,0.00008502479,0.000020806514,0.0003141245],"genre_scores_gemma":[0.998801,0.00013376129,0.00037712578,0.000014703818,0.0000019650838,0.000010858958,0.00015265855,0.0000033155147,0.0005046207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999286,0.000011702343,0.000008767777,0.00001606363,0.00001753665,0.000017253116],"domain_scores_gemma":[0.99993694,0.000012834955,0.000017194898,0.0000068639133,0.0000038736202,0.000022325865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013027196,0.00015285853,0.00014735348,0.00018692402,0.00010972914,0.00024087586,0.00008508135,0.00013881682,0.0008293655],"category_scores_gemma":[0.00011151104,0.0000945127,0.000079074605,0.0000911641,0.00020148771,0.00011431648,0.00012437743,0.0002825314,0.00017447793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022532305,0.00004268882,0.0036074265,0.000020930804,0.0000062812114,0.0001614868,0.000023707304,0.00007868601,0.9928669,0.00015901531,0.000051725543,0.002755836],"study_design_scores_gemma":[0.00006195168,0.0010119403,0.07120223,0.000011282143,0.00003345196,0.0025243524,0.00008677573,0.0022629844,0.91800946,0.00016711473,0.0046225917,0.000005845718],"about_ca_topic_score_codex":0.00023581699,"about_ca_topic_score_gemma":0.0005078403,"teacher_disagreement_score":0.0008293655,"about_ca_system_score_codex":0.00014281918,"about_ca_system_score_gemma":0.000118652126,"threshold_uncertainty_score":0.0027745366},"labels":[],"label_agreement":null},{"id":"W4416920916","doi":"10.1172/jci195987","title":"Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval; Arthritis Research Centre of Canada; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Platelet; Inflammation; Immune system; Neutrophil extracellular traps; Platelet activation; Context (archaeology); Receptor; Antigen-Antibody Complex; Rheumatoid arthritis","score_opus":0.0711297597143566,"score_gpt":0.39221598617491454,"score_spread":0.32108622646055796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416920916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862432,0.004826302,0.0066097705,0.00021435537,0.000036990637,0.0000624677,0.00011675235,0.000068507,0.0018215802],"genre_scores_gemma":[0.9951681,0.0008128101,0.0026182877,0.0001103684,0.000014954541,0.000049710845,0.0001309097,0.000005844811,0.0010890809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99972016,0.000079362544,0.000021036803,0.000049192335,0.00007534467,0.000054906388],"domain_scores_gemma":[0.9999316,0.000019574392,0.000018498387,0.000007945593,0.000010100363,0.00001231981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022621038,0.00019737578,0.00020506575,0.00007993861,0.00010764242,0.0004290743,0.00014686547,0.00030593696,0.0008857593],"category_scores_gemma":[0.0002436037,0.000103052975,0.00012411868,0.00008355944,0.00018839321,0.00017261863,0.00020400288,0.0004464758,0.00020547461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014969724,0.000022358907,0.00042390093,0.000041305088,0.0000054006273,0.00008931093,0.00002956125,0.000058950245,0.9965352,0.0001746285,0.00006447079,0.0024052672],"study_design_scores_gemma":[0.00008211081,0.0011005537,0.017887508,0.00002689106,0.00003637042,0.0008486936,0.000074354175,0.0024173215,0.9722711,0.00016977725,0.005077304,0.00000815223],"about_ca_topic_score_codex":0.00083864963,"about_ca_topic_score_gemma":0.0008665939,"teacher_disagreement_score":0.0008857593,"about_ca_system_score_codex":0.00027360138,"about_ca_system_score_gemma":0.00022603467,"threshold_uncertainty_score":0.0029631257},"labels":[],"label_agreement":null},{"id":"W4417000373","doi":"10.1172/jci196495","title":"Noncanonical functions of UGT2B17 promote castration-resistant prostate cancer progression","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Université Laval; Centre hospitalier universitaire de Québec; Centre hospitalier de l'Université Laval; Vancouver General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Prostate cancer; Tumor progression; Prostate; Cell growth; Androgen; Downregulation and upregulation; Transcription (linguistics); Androgen deprivation therapy","score_opus":0.10355666009587816,"score_gpt":0.4807232916004244,"score_spread":0.3771666315045462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417000373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809374,0.009780042,0.0029856074,0.00045640752,0.0001624223,0.000060737013,0.0007574318,0.00046867438,0.0043912167],"genre_scores_gemma":[0.9944583,0.0016313305,0.0004138463,0.000081874554,0.000013959677,0.000020872187,0.0004563614,0.000030971663,0.0028923454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987245,0.000021458913,0.0000051238417,0.000016380553,0.000038543323,0.000046042634],"domain_scores_gemma":[0.9998803,0.0000092231885,0.000023994788,0.000012398842,0.000014009936,0.000060027058],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013836064,0.00035564112,0.00032384408,0.00029483004,0.0001975,0.0005906797,0.00014192928,0.00023710364,0.0033719174],"category_scores_gemma":[0.00012929788,0.00016087927,0.00035722833,0.00023660278,0.00028622302,0.00015024285,0.00023214746,0.00089553377,0.0007177968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012777325,0.0002259152,0.0049408977,0.00030282818,0.00006415988,0.0005811277,0.00007816017,0.00063789065,0.97349507,0.0012109292,0.0018533269,0.01533198],"study_design_scores_gemma":[0.0001357981,0.0016342343,0.049718842,0.000035074096,0.00011139988,0.0025142916,0.00022664193,0.004617692,0.89792436,0.00055703975,0.042496677,0.000027885266],"about_ca_topic_score_codex":0.0012606033,"about_ca_topic_score_gemma":0.0019636753,"teacher_disagreement_score":0.0033719174,"about_ca_system_score_codex":0.0003459441,"about_ca_system_score_gemma":0.00050895486,"threshold_uncertainty_score":0.011280239},"labels":[],"label_agreement":null},{"id":"W4417230978","doi":"10.1172/jci188458","title":"CD8+ T cells in the tumor microenvironment modulate the response to endocrine therapy in breast cancer","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"National Cancer Institute; National Institutes of Health; Seagen; Puma Biotechnology; Susan G. Komen; Cancer Prevention and Research Institute of Texas; Daiichi Sankyo Europe; U.S. Department of Defense; Breast Cancer Research Foundation; Sanofi; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb; NightstaRx; University of Texas Southwestern Medical Center; Susan G. Komen for the Cure; Pfizer; Amgen","keywords":"Tumor microenvironment; Stromal cell; CXCL11; Letrozole; Immune system; CXCL10; CXCR3; Chemokine; Cytotoxic T cell","score_opus":0.044219122027332795,"score_gpt":0.37366916011851287,"score_spread":0.32945003809118006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417230978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99690056,0.0020201968,0.00023267171,0.000071995215,0.000009380703,0.000011343033,0.000186613,0.000015356436,0.00055193715],"genre_scores_gemma":[0.99767965,0.0007136036,0.00026832582,0.000084921434,0.000010167153,0.000020858282,0.00027271983,0.000004681533,0.0009451133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999089,0.000016947675,0.0000059276513,0.000020636407,0.000016460013,0.000031125684],"domain_scores_gemma":[0.99995184,0.000008253929,0.000014780687,0.0000032582795,0.000008596679,0.000013254505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008933604,0.0001070718,0.00016862541,0.0001804802,0.00008793303,0.0002448362,0.000056318426,0.00013504426,0.0011198955],"category_scores_gemma":[0.00012221701,0.00008074696,0.00012167455,0.00012594348,0.00009449126,0.0001142317,0.00011330869,0.00024444013,0.00019732608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001200874,0.00009499763,0.03794217,0.00015034944,0.000032147997,0.00018715288,0.00017622244,0.00034937728,0.9363176,0.00006822764,0.0003278581,0.023152955],"study_design_scores_gemma":[0.00011179694,0.001885214,0.6621313,0.00005079646,0.00018181304,0.0013607893,0.0011567287,0.0022830241,0.316575,0.00026372835,0.013974959,0.000024796364],"about_ca_topic_score_codex":0.00044139742,"about_ca_topic_score_gemma":0.000904333,"teacher_disagreement_score":0.0011198955,"about_ca_system_score_codex":0.00018957075,"about_ca_system_score_gemma":0.00012730206,"threshold_uncertainty_score":0.0037463903},"labels":[],"label_agreement":null}]}