{"meta":{"query_hash":"44802f85f351","filters":{"venue":"MedChemComm"},"cohort_total":115,"direct_labels_cover":0,"predictions_cover":115,"exported":115,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/44802f85f351","api":"https://metacan.xera.ac/api/v1/cohort?venue=MedChemComm"},"results":[{"id":"W1755513170","doi":"10.1039/c5md00365b","title":"Multi-drug delivery nanocarriers for combination therapy","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":127,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Nanocarriers; Drug delivery; Drug; Targeted drug delivery; Nanotechnology; Combination therapy; Medicine; Computer science; Pharmacology; Materials science","score_opus":0.04467246866883837,"score_gpt":0.2769833414436409,"score_spread":0.23231087277480253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1755513170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952524,0.0005214792,0.0015304055,0.00083532376,0.00094250654,0.0005255299,0.00003105274,0.00020559298,0.00015575095],"genre_scores_gemma":[0.9874734,0.000014544504,0.010915205,0.0007299733,0.00008962211,0.00014738576,0.000024864443,0.00003397686,0.00057101954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853057,0.00012061643,0.00027016486,0.00031764284,0.00033909208,0.00042189457],"domain_scores_gemma":[0.99877536,0.00017267193,0.00010835254,0.00039161672,0.00030072287,0.00025127683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011633764,0.00017245485,0.00021023685,0.000070682225,0.0001309549,0.00007973321,0.0003563771,0.00006594515,0.00008545142],"category_scores_gemma":[0.00019652118,0.00015667225,0.0000788534,0.00015454796,0.00011162385,0.00032572047,0.000063496336,0.000070825234,0.00031467696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021038232,0.00027747033,0.0009380592,0.000012637759,0.00000922393,0.000004059997,0.0012606193,0.000067565394,0.9793864,0.00019742314,0.014793345,0.0028428035],"study_design_scores_gemma":[0.0039481916,0.00012244092,0.00017856386,0.000012055585,0.000011183022,0.0000026742316,0.00040938763,0.003306942,0.9788367,0.00055205316,0.012399628,0.00022016304],"about_ca_topic_score_codex":0.00012388779,"about_ca_topic_score_gemma":0.00003385165,"teacher_disagreement_score":0.0093848,"about_ca_system_score_codex":0.0001624322,"about_ca_system_score_gemma":0.00016513957,"threshold_uncertainty_score":0.6388909},"labels":[],"label_agreement":null},{"id":"W1757631619","doi":"10.1039/c5md00210a","title":"Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitors","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Wellcome Trust","keywords":"Aryl; Combinatorial chemistry; Chemistry; Pharmacology; Stereochemistry; Biology; Organic chemistry","score_opus":0.022815970667538734,"score_gpt":0.24948142749381944,"score_spread":0.2266654568262807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1757631619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883604,0.0034627574,0.006790279,0.000263443,0.00033512092,0.00018740793,0.000005472463,0.0000174995,0.0005775964],"genre_scores_gemma":[0.9957582,0.00027831786,0.0027634415,0.00016164014,0.00018674895,0.000028196668,0.000060243685,0.000022502367,0.0007407075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990045,0.00003200294,0.0002522989,0.00028763956,0.0002093434,0.00021421773],"domain_scores_gemma":[0.9993963,0.000016967795,0.00010252547,0.0002514334,0.00010886369,0.00012391513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031821482,0.0001792223,0.00019158452,0.000046164216,0.000044644374,0.000027001,0.0001768913,0.0001402771,0.00000883299],"category_scores_gemma":[0.0000928688,0.00015888209,0.000052510004,0.000093016395,0.00015909426,0.00001252631,0.00015668354,0.00007678903,0.000010029815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032632006,0.00010061018,0.0058385194,0.000036857862,0.000108916895,0.000014320086,0.00036165142,0.00026408795,0.97810817,0.00011178868,0.012611064,0.002117725],"study_design_scores_gemma":[0.0007495341,0.0001613087,0.00037069435,0.000038168284,0.000027218608,0.000023741817,0.0001445388,0.000035243695,0.9903629,0.00036772998,0.0074889637,0.00022996517],"about_ca_topic_score_codex":0.000033035987,"about_ca_topic_score_gemma":0.0000037739305,"teacher_disagreement_score":0.012254755,"about_ca_system_score_codex":0.00002057755,"about_ca_system_score_gemma":0.00019769665,"threshold_uncertainty_score":0.64790237},"labels":[],"label_agreement":null},{"id":"W1766553222","doi":"10.1039/c5md00241a","title":"Discovery of high affinity inhibitors of <i>Leishmania donovani N</i>-myristoyltransferase","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kensington Health","funders":"Medical Research Council; Diamond Light Source; Seventh Framework Programme; Wellcome Trust; Wellcome","keywords":"Leishmania donovani; Leishmania; Chemistry; Biology; Stereochemistry; Leishmaniasis; Genetics; Visceral leishmaniasis; Computer science; Parasite hosting","score_opus":0.04233933231031607,"score_gpt":0.29760812162726435,"score_spread":0.2552687893169483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1766553222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98840207,0.0007876036,0.00017349,0.0021789884,0.00023676718,0.00042702106,0.00005167097,0.00005120957,0.007691184],"genre_scores_gemma":[0.99777037,0.00017823339,0.0010682242,0.00013927683,0.00017251198,0.00002475355,0.000030099356,0.000036635996,0.0005798951],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99761873,0.00010726353,0.00065160316,0.00030248082,0.0009537483,0.00036614607],"domain_scores_gemma":[0.9981619,0.0002213701,0.00016121952,0.0006864746,0.00053285575,0.0002361727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079504395,0.00023259217,0.00085128576,0.00019838977,0.00004150725,0.000013113387,0.00024887506,0.000112299815,0.000038133716],"category_scores_gemma":[0.00095881877,0.00018983113,0.00019485847,0.00046789472,0.00045308267,0.0002387215,0.0001756287,0.000334899,0.000022052305],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005011095,0.0057279156,0.425512,0.003052379,0.0015158871,0.0003881339,0.0066472385,0.00003072002,0.36935994,0.0075285253,0.1652394,0.0099868],"study_design_scores_gemma":[0.004432559,0.0011241541,0.049048632,0.00029086907,0.00015971297,0.00003538869,0.0011717491,0.00001174325,0.93787324,0.00076541293,0.0048337686,0.0002527937],"about_ca_topic_score_codex":0.0010824766,"about_ca_topic_score_gemma":0.00014906099,"teacher_disagreement_score":0.5685133,"about_ca_system_score_codex":0.00013084976,"about_ca_system_score_gemma":0.0003077032,"threshold_uncertainty_score":0.7741089},"labels":[],"label_agreement":null},{"id":"W1804529701","doi":"10.1039/c5md00147a","title":"Synthesis and in vitro assessment of chemically modified siRNAs targeting BCL2 that contain 2′-ribose and triazole-linked backbone modifications","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Tech University; Lakeridge Health","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Small interfering RNA; Gene silencing; In vitro; Gene; Gene expression; Chemistry; RNA; Biology; Cell biology; Biochemistry","score_opus":0.0421921579849269,"score_gpt":0.29256055897941696,"score_spread":0.2503684009944901,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1804529701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99651635,0.0010105191,0.0009340781,0.00037212446,0.00003461784,0.0001738367,0.000025257776,0.000006999807,0.0009262313],"genre_scores_gemma":[0.9972475,0.00030093562,0.0020828573,0.0000915933,0.000041488984,0.00005266174,0.00007938759,0.000013565179,0.00008996725],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902546,0.000082848455,0.0002884202,0.0002900488,0.00012660187,0.00018659752],"domain_scores_gemma":[0.999357,0.00006533427,0.00011631476,0.00025079882,0.000092628696,0.00011795054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048301174,0.00014688457,0.00026544748,0.00005468143,0.000028692304,0.000019948257,0.00014499469,0.00014182125,0.000004441685],"category_scores_gemma":[0.0002490046,0.00013890395,0.000042788306,0.00006011183,0.00010241852,0.000008448641,0.00012952338,0.00010695677,7.667713e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002137348,0.00008911824,0.0030021258,0.000021292195,0.000035270517,0.0000018575017,0.00010658512,0.000029200757,0.9945152,0.000024972436,0.00030638947,0.0016542505],"study_design_scores_gemma":[0.0010831043,0.00006649353,0.0037564526,0.00002546188,0.000024062094,0.000005200955,0.00045977463,0.002416158,0.99152124,0.00009712823,0.00038000158,0.00016492933],"about_ca_topic_score_codex":0.000067144625,"about_ca_topic_score_gemma":0.000017437304,"teacher_disagreement_score":0.00299397,"about_ca_system_score_codex":0.000021890357,"about_ca_system_score_gemma":0.000075356766,"threshold_uncertainty_score":0.5664339},"labels":[],"label_agreement":null},{"id":"W1827248985","doi":"10.1039/c5md00108k","title":"Effect of dibucaine hydrochloride on raft-like lipid domains in model membrane systems","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hatch (Canada)","funders":"","keywords":"Dipalmitoylphosphatidylcholine; Dibucaine; Raft; Chemistry; Liposome; Hydrochloride; Lidocaine Hydrochloride; Chromatography; Membrane; Polymer; Organic chemistry; Phospholipid; Anesthesia; Copolymer; Biochemistry; Lidocaine; Medicine","score_opus":0.01148220352325689,"score_gpt":0.2634679587119307,"score_spread":0.2519857551886738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1827248985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961853,0.00016132327,0.00011028188,0.00006371046,0.00058831356,0.0003557429,0.000026711572,0.000017574604,0.002491042],"genre_scores_gemma":[0.9983201,0.000031864227,0.00007236114,0.00011181999,0.00038768293,0.000055842054,0.00014522282,0.00003470032,0.0008404323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985995,0.00013627764,0.0003303803,0.0003528868,0.00027651872,0.0003043792],"domain_scores_gemma":[0.9990518,0.000039366158,0.00010516894,0.00058461213,0.00005648239,0.00016254578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006288329,0.0002565357,0.00041151204,0.00008646478,0.000024133042,0.000011703239,0.00028494187,0.00021872483,0.000004610922],"category_scores_gemma":[0.00012585829,0.00020011785,0.000113016766,0.00013320101,0.00006925755,0.000005079049,0.00010024358,0.00016472263,0.000011622533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074688887,0.00009370633,0.0012426364,0.00014755895,0.000028056169,0.000009057519,0.00010359587,0.005134633,0.9908465,0.00003460221,0.0011276113,0.0004851312],"study_design_scores_gemma":[0.0025973779,0.00088912155,0.000058341822,0.00005106797,0.000041849748,0.00001780607,0.000028113218,0.0014141129,0.9895227,0.0000054700654,0.0051549757,0.00021904527],"about_ca_topic_score_codex":0.00006856442,"about_ca_topic_score_gemma":0.00003135627,"teacher_disagreement_score":0.0040273643,"about_ca_system_score_codex":0.00003591843,"about_ca_system_score_gemma":0.00007882528,"threshold_uncertainty_score":0.8160569},"labels":[],"label_agreement":null},{"id":"W1924569161","doi":"10.1039/c5md90032h","title":"Correction: Identification of a novel class of autotaxin inhibitors through cross-screening","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cystic Fibrosis Canada","funders":"","keywords":"Autotaxin; Identification (biology); Class (philosophy); Computational biology; Computer science; Bioinformatics; Chemistry; Artificial intelligence; Biology; Biochemistry; Lysophosphatidic acid","score_opus":0.0887488986745686,"score_gpt":0.3935148326447293,"score_spread":0.3047659339701607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1924569161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98605883,0.00044064494,0.0032269657,0.00078029453,0.0017664031,0.00026942106,0.000015169298,0.000046756348,0.0073955413],"genre_scores_gemma":[0.9946794,0.000012969727,0.0010409806,0.000086470856,0.00021126248,0.000021472963,0.000040448154,0.000012423746,0.0038945875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991335,0.000019966144,0.0003792888,0.00014130682,0.00021365126,0.00011224737],"domain_scores_gemma":[0.9992207,0.00006233097,0.00023474969,0.00019343353,0.00022225076,0.0000664785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023229787,0.00008987868,0.0002555405,0.000055953027,0.00002389877,0.000004932987,0.000059403283,0.00007913243,0.00008408608],"category_scores_gemma":[0.00010092252,0.000082023274,0.00008110269,0.00022524076,0.0001257245,0.00008633373,0.000030520205,0.00011063088,0.000006390243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018893856,0.0026023544,0.24421157,0.0002932985,0.000480926,0.000013244911,0.007713403,0.00044311784,0.6286571,0.00036416532,0.10171606,0.011615396],"study_design_scores_gemma":[0.0057207034,0.0004361344,0.033343453,0.00009103625,0.00018937228,0.000047003137,0.0003811466,0.0023541476,0.9338725,0.000047871614,0.023416782,0.000099828845],"about_ca_topic_score_codex":0.00028339727,"about_ca_topic_score_gemma":0.000018838662,"teacher_disagreement_score":0.30521545,"about_ca_system_score_codex":0.00008346438,"about_ca_system_score_gemma":0.00010485922,"threshold_uncertainty_score":0.3344812},"labels":[],"label_agreement":null},{"id":"W1928502853","doi":"10.1039/c5md00152h","title":"Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Ministero dello Sviluppo Economico; Ontario Ministry of Economic Development and Innovation; British Heart Foundation; Wellcome Trust; Genome Canada; Directorate for Biological Sciences; Wellcome; GlaxoSmithKline; European Commission; Pfizer; Eli Lilly and Company","keywords":"Bromodomain; Chemistry; Computational biology; Pharmacology; Biology; Biochemistry; Acetylation; Gene","score_opus":0.01581447698278131,"score_gpt":0.22894704749450281,"score_spread":0.21313257051172152,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1928502853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951556,0.0016517487,0.002213565,0.00016567462,0.000029405897,0.00018081036,0.000006762839,0.0000049667133,0.000591502],"genre_scores_gemma":[0.9959883,0.00019173622,0.003658149,0.00003487691,0.000030550167,0.000011143957,0.0000047823346,0.000009921873,0.000070555754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938864,0.0000850039,0.00016099852,0.00017543578,0.00009520384,0.0000947281],"domain_scores_gemma":[0.9995717,0.000034951667,0.00008861692,0.00012588201,0.000082442915,0.00009642358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002874617,0.000096461656,0.00015980586,0.000039651943,0.000024919003,0.0000066302305,0.00004758325,0.00009401575,9.57253e-7],"category_scores_gemma":[0.00024254728,0.00008656046,0.000019341891,0.00005908193,0.0001726624,0.000005164194,0.00009095867,0.000042321033,1.984084e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017941884,0.00010532548,0.0056599206,0.000066699555,0.00007586359,0.0000012370693,0.00038971016,0.000005974538,0.9718695,0.00010198251,0.0025624945,0.018981857],"study_design_scores_gemma":[0.0004909556,0.00026820286,0.0015298199,0.000025290983,0.000019362707,0.000016075377,0.00015811651,0.00007487066,0.9962575,0.00017994535,0.0008860684,0.000093786686],"about_ca_topic_score_codex":0.000032272303,"about_ca_topic_score_gemma":0.0000046692903,"teacher_disagreement_score":0.02438799,"about_ca_system_score_codex":0.000006654394,"about_ca_system_score_gemma":0.000039482627,"threshold_uncertainty_score":0.35298333},"labels":[],"label_agreement":null},{"id":"W1950580375","doi":"10.1039/c5md00303b","title":"2-[<sup>18</sup>F]Fluoroethyl tosylate – a versatile tool for building<sup>18</sup>F-based radiotracers for positron emission tomography","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Lanthanide and Transition Metal Complexes","field":"Materials Science","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Helmholtz-Zentrum Dresden-Rossendorf","keywords":"Amine gas treating; Reagent; Radiochemistry; Chemistry; Reactivity (psychology); Positron; Physics; Physical chemistry; Nuclear physics; Organic chemistry; Medicine","score_opus":0.04230806980646652,"score_gpt":0.28940123457413747,"score_spread":0.24709316476767096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1950580375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.944507,0.000524866,0.04833633,0.001991778,0.0004481475,0.002280348,0.00084360625,0.0004674312,0.00060049904],"genre_scores_gemma":[0.9437849,0.000008749535,0.05357369,0.00088094216,0.00042396272,0.00053325447,0.00036394666,0.00010430564,0.0003262567],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965222,0.00021451841,0.00071009924,0.0008694731,0.000690192,0.0009935299],"domain_scores_gemma":[0.9975593,0.00061766757,0.00022881411,0.0007594943,0.00035193708,0.00048276584],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016075167,0.0005451958,0.00074052426,0.00027140373,0.00045622623,0.00026426458,0.00072159775,0.00026899026,0.0007775704],"category_scores_gemma":[0.00032566368,0.00047825847,0.0005365074,0.00038768986,0.00020124862,0.0005378776,0.00008719914,0.00022328469,0.00006212035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002290741,0.00041577482,0.0005520333,0.00050584454,0.00011626379,0.0000171678,0.0017923262,0.0072963457,0.920382,0.0005448704,0.06420322,0.0018834095],"study_design_scores_gemma":[0.0053797755,0.00083212164,0.0000724108,0.00015226129,0.00023973771,0.000017310304,0.00033200017,0.036267027,0.89049643,0.0029253054,0.062497918,0.0007877089],"about_ca_topic_score_codex":0.000110758396,"about_ca_topic_score_gemma":0.0000076271854,"teacher_disagreement_score":0.029885583,"about_ca_system_score_codex":0.00017884318,"about_ca_system_score_gemma":0.0002305692,"threshold_uncertainty_score":0.9997669},"labels":[],"label_agreement":null},{"id":"W1953955952","doi":"10.1039/c5md00038f","title":"Selective neuronal targeting, protection and signaling network analysis via dopamine-mediated mesoporous silica nanoparticles","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Public Health","funders":"National Natural Science Foundation of China","keywords":"Mesoporous silica; Dopaminergic; Dopamine; Glutathione; Nanoparticle; Chemistry; Mesoporous material; Nanotechnology; Neuroscience; Materials science; Biochemistry; Biology; Enzyme; Catalysis","score_opus":0.014742555223642286,"score_gpt":0.238498475849273,"score_spread":0.2237559206256307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1953955952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99508154,0.0010878796,0.0029819782,0.00022123588,0.00015274632,0.00021849165,0.0000051968777,0.000051443785,0.00019945877],"genre_scores_gemma":[0.99723834,0.00002121661,0.0017206728,0.00024414432,0.00043851195,0.00006233747,0.00018363798,0.000024278033,0.00006684023],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843705,0.00026596955,0.0002794128,0.0004829613,0.00015636609,0.00037821682],"domain_scores_gemma":[0.99920076,0.000051325558,0.00013996958,0.00026057282,0.00017319227,0.00017420624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005487703,0.0002072116,0.00026502102,0.00007034931,0.000119734796,0.000026358652,0.00016425135,0.00018846855,0.000011964556],"category_scores_gemma":[0.00041346392,0.00019519421,0.000084340856,0.00047214856,0.00014538268,0.0000057988386,0.00017060919,0.00016992168,0.000008719545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017237388,0.00005452587,0.03209186,0.000005617545,0.00033538466,0.000003819196,0.000083813255,0.0011163309,0.9641149,0.0000057567704,0.0012264597,0.0007891379],"study_design_scores_gemma":[0.0009526001,0.0007633308,0.008588029,0.0000053632566,0.00024952157,0.000041006133,0.00011024565,0.0048656766,0.97060007,0.0004243944,0.01294629,0.0004534842],"about_ca_topic_score_codex":0.00006805624,"about_ca_topic_score_gemma":0.00007590947,"teacher_disagreement_score":0.02350383,"about_ca_system_score_codex":0.000031441286,"about_ca_system_score_gemma":0.00005406845,"threshold_uncertainty_score":0.7959789},"labels":[],"label_agreement":null},{"id":"W1967622081","doi":"10.1039/c4md00495g","title":"Naturally occurring FANCF–Hes1 complex inhibitors from <i>Wrightia religiosa</i>","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Blood Services; Chiba University; Tokyo Biochemical Research Foundation; Canadian Institutes of Health Research; Fanconi Anemia Research Fund","keywords":"HES1; Chemistry; Computational biology; Biology; Biochemistry; Gene","score_opus":0.006941080097586082,"score_gpt":0.2241519662368765,"score_spread":0.2172108861392904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967622081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863926,0.0013217104,0.00013359543,0.0012182553,0.00070427544,0.00016932425,0.000023127343,0.000064822,0.00997227],"genre_scores_gemma":[0.99301255,0.00008100192,0.0018048242,0.0021686924,0.0015225825,0.000007715531,0.000497595,0.00003490707,0.0008701325],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985418,0.00007258455,0.00027141167,0.00055610936,0.00020234028,0.00035579733],"domain_scores_gemma":[0.99896634,0.000029540071,0.00010827223,0.00066796987,0.00008975322,0.00013812051],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021247315,0.00026169943,0.00024091762,0.000038622897,0.00012287061,0.000041265408,0.00040380986,0.0002006405,0.000094380215],"category_scores_gemma":[0.00019558964,0.00021909848,0.00013084005,0.00011061061,0.00007474887,0.0000068018135,0.00034343096,0.00026146983,0.00006439424],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079611535,0.000049336515,0.0060985168,0.000026599968,0.00006404238,0.0000035922708,0.000040016468,0.000009053775,0.867544,0.00024412175,0.110063516,0.015777582],"study_design_scores_gemma":[0.00045775136,0.00008510456,0.005838918,0.000016351496,0.00001578965,0.0000066388916,0.0000094413945,0.00009301065,0.39850634,0.00032731725,0.59434694,0.00029639],"about_ca_topic_score_codex":0.00022131292,"about_ca_topic_score_gemma":0.00013678434,"teacher_disagreement_score":0.48428345,"about_ca_system_score_codex":0.000014126306,"about_ca_system_score_gemma":0.000023561526,"threshold_uncertainty_score":0.89345765},"labels":[],"label_agreement":null},{"id":"W1969958049","doi":"10.1039/c4md00104d","title":"A mechanistic study on the α-<i>N</i>-acetylgalactosaminidase from <i>E. meningosepticum</i>: a family 109 glycoside hydrolase","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Burnaby Hospital; Simon Fraser University","funders":"","keywords":"Glycoside hydrolase; Stereochemistry; Mechanism (biology); Glycoside; Chemistry; Biology; Enzyme; Biochemistry; Philosophy; Epistemology","score_opus":0.014534184975660138,"score_gpt":0.23060897501591296,"score_spread":0.21607479004025282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969958049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926105,0.000036927486,0.0036398685,0.0011565774,0.00026727936,0.00036520523,0.00001726238,0.00004619933,0.0018601903],"genre_scores_gemma":[0.9953145,0.000011399325,0.00014032185,0.0031707732,0.0004893879,0.00010633865,0.00018819129,0.00003632145,0.0005427837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986043,0.0002684034,0.00023031479,0.00045521633,0.00022803957,0.00021371282],"domain_scores_gemma":[0.9989186,0.00006683378,0.0001131979,0.00076009915,0.00005029332,0.000090958485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038102444,0.00021665012,0.00016377115,0.000030448702,0.00017496635,0.0000579127,0.0002755887,0.000090984264,0.000074819785],"category_scores_gemma":[0.00032543074,0.00016029934,0.00007309803,0.000105628766,0.000044057135,0.000004811036,0.00011170009,0.00015907873,0.00010903332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010969559,0.00029649294,0.00058033684,0.0000028721086,0.000048917675,0.0000015899326,0.0002248238,0.000007001359,0.9950057,0.00018827297,0.0027822787,0.0007519795],"study_design_scores_gemma":[0.0010265408,0.00075936556,0.004716459,0.000015308922,0.000055430504,0.0000040493346,0.0005753674,0.00032463478,0.9416931,0.0001918678,0.050346214,0.0002916516],"about_ca_topic_score_codex":0.000029087745,"about_ca_topic_score_gemma":0.000018062843,"teacher_disagreement_score":0.05331263,"about_ca_system_score_codex":0.0000132301575,"about_ca_system_score_gemma":0.000021892256,"threshold_uncertainty_score":0.65368176},"labels":[],"label_agreement":null},{"id":"W1973471043","doi":"10.1039/c2md20120h","title":"Informatic strategies for the discovery of polyketides and nonribosomal peptides","year":2012,"lang":"en","type":"article","venue":"MedChemComm","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Nonribosomal peptide; Computational biology; Combinatorial chemistry; Chemistry; Biology; Biochemistry; Biosynthesis; Gene","score_opus":0.020251576220520092,"score_gpt":0.2626384725038811,"score_spread":0.24238689628336102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973471043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930838,0.0028400098,0.0001230614,0.0027123434,0.00009721222,0.00032969835,0.00001605767,0.000012687295,0.00078515697],"genre_scores_gemma":[0.9979722,0.00011070045,0.000979015,0.00029295983,0.00021514199,0.0000028752224,0.000006098067,0.0000070925867,0.0004139274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995001,0.000009781193,0.00017174575,0.00005887194,0.00008530395,0.00017420888],"domain_scores_gemma":[0.99943113,0.0002555471,0.000066061955,0.00016845479,0.000038528284,0.00004026808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026248855,0.00008764497,0.00017801957,0.000027310463,0.00006304644,0.000028550574,0.00006231209,0.000039615315,0.000018163717],"category_scores_gemma":[0.00017089878,0.00004368993,0.000058136662,0.000055442637,0.00013355457,0.00034550895,0.00004011472,0.000073555675,0.0000020423347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005335363,0.00024792223,0.02233751,0.0020490657,0.0003162645,6.966361e-7,0.004425852,8.7372706e-7,0.91984516,0.009477817,0.009619597,0.031145686],"study_design_scores_gemma":[0.0007239481,0.0001949795,0.057661172,0.00019423282,0.00028707675,0.00006837935,0.0052746665,0.000060981627,0.9156604,0.00030682457,0.019394562,0.0001727849],"about_ca_topic_score_codex":0.00003611466,"about_ca_topic_score_gemma":0.0000065522754,"teacher_disagreement_score":0.035323665,"about_ca_system_score_codex":0.000007597191,"about_ca_system_score_gemma":0.000029273268,"threshold_uncertainty_score":0.17816237},"labels":[],"label_agreement":null},{"id":"W1980498259","doi":"10.1039/c4md00067f","title":"Sulfonium ions as inhibitors of the mycobacterial galactofuranosyltransferase GlfT2","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Glycomics Centre; Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Sulfonium; Moiety; Galactan; Stereochemistry; Ion; Chemistry; Combinatorial chemistry; Biochemistry; Cell wall; Organic chemistry","score_opus":0.004573422685683357,"score_gpt":0.18627289047328024,"score_spread":0.18169946778759688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980498259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.920311,0.000026101761,0.000010018514,0.0007711463,0.00035352545,0.00004907313,0.00004330146,0.00006348238,0.07837236],"genre_scores_gemma":[0.99785465,0.000011316287,0.000023054841,0.00009008949,0.0005774139,0.000019538476,0.000024041572,0.000030457484,0.0013694541],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868554,0.00005012901,0.0003864972,0.00027206753,0.00031020006,0.00029556133],"domain_scores_gemma":[0.9985856,0.00027277603,0.00011455054,0.00083990453,0.000061614504,0.00012556539],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018867844,0.0002315055,0.00030636907,0.000021079144,0.00013839318,0.00003082976,0.0004992474,0.00021701635,0.0028017832],"category_scores_gemma":[0.00038236665,0.0001751109,0.00030258344,0.0001618042,0.00020724778,0.000060832546,0.000091121765,0.00028425257,0.00003730953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054000324,0.00009438403,0.0019553564,0.00012207823,0.00003257555,0.0000014370705,0.00022280568,0.000002408763,0.9958692,0.00019398976,0.0007423882,0.0007093632],"study_design_scores_gemma":[0.00047445254,0.000008311075,0.0002880145,0.000089908965,0.00005768259,0.000012572349,0.0000942296,0.000020812426,0.97556424,0.00026108895,0.022930305,0.00019837008],"about_ca_topic_score_codex":0.00008695428,"about_ca_topic_score_gemma":0.000016783726,"teacher_disagreement_score":0.07754364,"about_ca_system_score_codex":0.000046035373,"about_ca_system_score_gemma":0.00006881028,"threshold_uncertainty_score":0.9981098},"labels":[],"label_agreement":null},{"id":"W1981082478","doi":"10.1039/c4md00269e","title":"Structural biology and chemistry of protein arginine methyltransferases","year":2014,"lang":"en","type":"review","venue":"MedChemComm","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium; Toronto Public Health","funders":"Ministero dello Sviluppo Economico; Ontario Ministry of Economic Development and Innovation; Ontario Genomics Institute; Ontario Genomics; Genome Canada; Wellcome Trust; GlaxoSmithKline; Eli Lilly and Company","keywords":"Methyltransferase; Arginine; Computational biology; Structural biology; Protein chemistry; Chemistry; Biochemistry; Biology; Methylation; Amino acid","score_opus":0.01622034578541325,"score_gpt":0.3127440147423163,"score_spread":0.296523668956903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981082478","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008360067,0.99053705,0.00015948011,0.000022842507,0.000087616914,0.00047553345,0.00009176976,0.000012912339,0.0002527355],"genre_scores_gemma":[0.006187072,0.99105954,0.0003928024,0.000008475082,0.00044754034,0.00009242605,0.001355635,0.000058094636,0.00039839762],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99859285,0.00012690588,0.0005019219,0.00047259819,0.000087706816,0.00021802247],"domain_scores_gemma":[0.99904376,0.000030347323,0.0002838003,0.00050299295,0.00006069617,0.000078382756],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017881802,0.0003680839,0.0010448014,0.00004765713,0.00003496936,0.000008378935,0.00023168387,0.0006849766,0.00005833504],"category_scores_gemma":[0.000093183575,0.0003122532,0.00026063286,0.00010702816,0.00020324813,0.0000016329717,0.000106854764,0.00021217419,0.0000019670542],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021461197,0.000014004815,0.000010847465,0.010566545,0.0003191589,4.9397426e-7,0.000009522599,0.000002691232,0.08526333,0.000043407792,0.00014921087,0.9035993],"study_design_scores_gemma":[0.00028440473,0.00009925036,0.0000035396818,0.0012303513,0.00026481427,0.000040213436,0.0000023008602,0.000008021999,0.09029359,0.000052174233,0.9073885,0.0003328135],"about_ca_topic_score_codex":0.000014778447,"about_ca_topic_score_gemma":0.000006031221,"teacher_disagreement_score":0.9072393,"about_ca_system_score_codex":0.000021110784,"about_ca_system_score_gemma":0.00013758903,"threshold_uncertainty_score":0.99993294},"labels":[],"label_agreement":null},{"id":"W1988851183","doi":"10.1039/c4md00244j","title":"Adamantane amine derivatives as dual acting NMDA receptor and voltage-gated calcium channel inhibitors for neuroprotection","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bell (Canada)","funders":"University of the Western Cape; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; National Research Foundation","keywords":"Neuroprotection; Adamantane; NMDA receptor; Chemistry; Calcium channel; Dual (grammatical number); Amine gas treating; Pharmacology; Ion channel; Voltage-dependent calcium channel; Calcium; Neuroscience; Biophysics; Combinatorial chemistry; Receptor; Biochemistry; Medicine; Biology; Organic chemistry; Philosophy","score_opus":0.018184571722097354,"score_gpt":0.27380128191619063,"score_spread":0.25561671019409327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988851183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939587,0.00013274924,0.0039028595,0.0009774569,0.0004373726,0.00034273363,0.000013601074,0.00003433879,0.00020019618],"genre_scores_gemma":[0.9969287,0.00006658569,0.00045280377,0.0010450834,0.0007034391,0.000058753765,0.0001356574,0.00003712621,0.0005718732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990111,0.00007566084,0.00019723506,0.00037377933,0.00008071884,0.00026153345],"domain_scores_gemma":[0.99945706,0.000051427287,0.000104347004,0.00016426327,0.00011485275,0.00010806129],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023176521,0.00018119515,0.0001971403,0.000045830082,0.00018575136,0.000021223275,0.00007785051,0.00016780812,0.000022995584],"category_scores_gemma":[0.00035288223,0.00016413617,0.000057234138,0.00006858805,0.00009006126,0.00000680855,0.00011711384,0.00013690352,0.0000055977766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017302239,0.000048726135,0.00010926993,0.0000307096,0.000034165583,9.476271e-7,0.00006186345,0.000005629378,0.98929876,0.000019820864,0.004457016,0.005760069],"study_design_scores_gemma":[0.0009707059,0.000668534,0.00020760142,0.000011352873,0.000017800086,0.000016397638,0.00011317037,0.0005027847,0.88023823,0.000042268515,0.11702714,0.00018400855],"about_ca_topic_score_codex":0.000031124942,"about_ca_topic_score_gemma":0.000011495979,"teacher_disagreement_score":0.11257013,"about_ca_system_score_codex":0.000007854832,"about_ca_system_score_gemma":0.000019092122,"threshold_uncertainty_score":0.6693279},"labels":[],"label_agreement":null},{"id":"W1991881216","doi":"10.1039/c4md00072b","title":"Synthesis of 4′-deoxy-4′-fluoro neamine and 4′-deoxy-4′-fluoro 4′-<i>epi</i>neamine","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Université de Montréal; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología","keywords":"Stereochemistry; Chemistry","score_opus":0.04703665631681562,"score_gpt":0.36995757384896716,"score_spread":0.3229209175321515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991881216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9607882,0.0016064042,0.00022713727,0.0036585052,0.0010371335,0.0004316001,0.00011520976,0.00031901282,0.031816833],"genre_scores_gemma":[0.9921413,0.00039985747,0.0016904604,0.0014654883,0.00083713315,0.00009275621,0.000041652318,0.000116651216,0.003214677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965664,0.00044703344,0.0009573983,0.00076588057,0.00041073875,0.00085255946],"domain_scores_gemma":[0.9950515,0.0028643962,0.0004034394,0.0009512933,0.00019495655,0.00053442526],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015678008,0.0006142724,0.0009848012,0.00014516947,0.00024729385,0.000031178883,0.00082141446,0.00072734803,0.003071242],"category_scores_gemma":[0.0018175782,0.000613407,0.00020354506,0.0004087825,0.00078323996,0.00016427251,0.00051288266,0.0011742561,0.00019490541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036252348,0.00083365425,0.02377952,0.000759121,0.00045541025,0.000040446328,0.00056070706,0.000029208157,0.8420428,0.0011907548,0.028995994,0.10094983],"study_design_scores_gemma":[0.0015470828,0.00012459948,0.002170163,0.00005994098,0.00030242308,0.000099255354,0.00009230141,0.0011991336,0.81154805,0.00045281125,0.18188615,0.0005180627],"about_ca_topic_score_codex":0.00007098082,"about_ca_topic_score_gemma":0.000016768652,"teacher_disagreement_score":0.15289016,"about_ca_system_score_codex":0.00011393894,"about_ca_system_score_gemma":0.00009119456,"threshold_uncertainty_score":0.9996317},"labels":[],"label_agreement":null},{"id":"W1992462013","doi":"10.1039/c4md00197d","title":"Prekinamycin and an isosteric-isoelectronic analogue exhibit comparable cytotoxicity towards K562 human leukemia cells","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; American Chemical Society Petroleum Research Fund","keywords":"K562 cells; Cytotoxicity; Leukemia; Chemistry; Cancer research; Stereochemistry; Computational biology; Combinatorial chemistry; Biology; Biochemistry; Genetics; In vitro","score_opus":0.014123767376432273,"score_gpt":0.27307447564057863,"score_spread":0.25895070826414635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992462013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99185985,0.00045141135,0.0047858907,0.00007811357,0.00010000789,0.0002019848,0.000016030299,0.000030520423,0.0024761932],"genre_scores_gemma":[0.9973015,0.00013284138,0.0005204228,0.00080489577,0.0002873374,0.00003110569,0.00014955454,0.000038755832,0.00073357334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986404,0.000098097094,0.00021544065,0.00048098242,0.00013996863,0.00042510798],"domain_scores_gemma":[0.9991177,0.0000072533717,0.00009009248,0.00055906293,0.000050808932,0.00017513806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032035832,0.00024151524,0.00026671516,0.00004235097,0.00017229008,0.000058702775,0.00027387735,0.00017823152,0.00004813832],"category_scores_gemma":[0.0000067701963,0.00023917366,0.000073130665,0.00007636098,0.000083418156,0.0000075233334,0.00015055524,0.00016313128,0.0000076038323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004436839,0.000058328067,0.00017405738,0.000023122937,0.000034324716,8.7839146e-7,0.0000784026,0.000026601447,0.9945911,0.00065311044,0.00044923738,0.0038664562],"study_design_scores_gemma":[0.00078136317,0.0010023771,0.0007868304,0.000011274231,0.00002973295,0.00001002499,0.000035336954,0.00073949364,0.9580316,0.00079422194,0.037470248,0.00030752004],"about_ca_topic_score_codex":0.00021155691,"about_ca_topic_score_gemma":0.000477133,"teacher_disagreement_score":0.03702101,"about_ca_system_score_codex":0.00006974128,"about_ca_system_score_gemma":0.00008358597,"threshold_uncertainty_score":0.9753219},"labels":[],"label_agreement":null},{"id":"W1995681224","doi":"10.1039/c4md00089g","title":"Inhibitors of the human neuraminidase enzymes","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Glycomics Centre; Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neuraminidase; Enzyme; Biochemistry; Chemistry; Biology","score_opus":0.010034918709655281,"score_gpt":0.2668816961411254,"score_spread":0.2568467774314701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995681224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913633,0.00009093809,0.0000896651,0.00050292833,0.00007718274,0.00012043002,0.0000029600137,0.000006127321,0.0077464865],"genre_scores_gemma":[0.9974202,0.0000035191592,0.000060532337,0.00018078074,0.00013279107,0.000010544878,0.00001580467,0.000010055913,0.0021658079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993289,0.000095546624,0.00013662901,0.00013755476,0.00016947198,0.00013188238],"domain_scores_gemma":[0.9993989,0.000011661329,0.00005322765,0.00043220932,0.00005833698,0.00004569735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022222965,0.00007240344,0.00007657855,0.00002155153,0.0000817176,0.00000938766,0.00025055284,0.000071325274,0.000054754084],"category_scores_gemma":[0.00020161652,0.000049947943,0.00007575462,0.000082339226,0.00010978436,0.000001375114,0.0001550862,0.00008659836,0.000009127121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007209087,0.000039011506,0.008428042,0.00001463847,0.000008750194,1.6649959e-7,0.000026904914,0.000006286443,0.98249704,0.00073439983,0.0051487945,0.0030887409],"study_design_scores_gemma":[0.0002400886,0.000067887515,0.008382315,0.000006604693,0.0000026784398,0.0000017463748,0.000014414633,0.000030457399,0.89146924,0.00008448036,0.0996449,0.00005518122],"about_ca_topic_score_codex":0.00002346085,"about_ca_topic_score_gemma":0.000029688124,"teacher_disagreement_score":0.09449611,"about_ca_system_score_codex":0.0000038540884,"about_ca_system_score_gemma":0.000019347854,"threshold_uncertainty_score":0.2036818},"labels":[],"label_agreement":null},{"id":"W1999551855","doi":"10.1039/c2md20159c","title":"A monomeric form of iNOS can rationalise observed SAR for inhibitors of dimerisation: quantum mechanics and docking compared","year":2012,"lang":"en","type":"article","venue":"MedChemComm","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Lipophilicity; Molecular mechanics; Docking (animal); Monomer; Chemistry; Computational chemistry; Quantum; Stereochemistry; Combinatorial chemistry; Molecular dynamics; Physics; Quantum mechanics; Polymer; Organic chemistry","score_opus":0.05155702467985642,"score_gpt":0.2564358143193926,"score_spread":0.20487878963953618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999551855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978655,0.0007742338,0.0007909437,0.00014041329,0.00009902911,0.00011230364,0.00007255065,0.000018545374,0.0001264528],"genre_scores_gemma":[0.99856,0.000034853838,0.0011301305,0.000025744725,0.00012609272,0.00001823583,0.00006407957,0.000016851049,0.000023992436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910265,0.000011569496,0.0004021066,0.00011925894,0.00016616198,0.0001982712],"domain_scores_gemma":[0.9992352,0.00014321636,0.00027138172,0.00018272232,0.00007301426,0.00009448059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018640146,0.00012081672,0.0003004643,0.000033672506,0.00005792287,0.000007854586,0.000108061024,0.000077542056,0.00007828903],"category_scores_gemma":[0.0000987184,0.00011471857,0.00008024869,0.00009198361,0.000046523586,0.00011204992,0.000046085865,0.00006934269,3.788189e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014671037,0.0005923832,0.07858809,0.0017228391,0.0002017841,6.6333564e-7,0.004614797,0.000036618214,0.8923471,0.015256578,0.0011454931,0.0053469194],"study_design_scores_gemma":[0.0016977678,0.000049061367,0.00540771,0.00022827761,0.00008486895,0.000005653106,0.0010130487,0.019354459,0.96477467,0.0035572778,0.0035267605,0.00030045002],"about_ca_topic_score_codex":0.00010276056,"about_ca_topic_score_gemma":0.000017422606,"teacher_disagreement_score":0.07318038,"about_ca_system_score_codex":0.000027319595,"about_ca_system_score_gemma":0.000035811867,"threshold_uncertainty_score":0.46780872},"labels":[],"label_agreement":null},{"id":"W1999602199","doi":"10.1039/c4md00211c","title":"Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Public Health","funders":"University of Sussex; University of Greenwich","keywords":"Histone deacetylase; Kinase; Chemistry; Pharmacology; Biology; Stereochemistry; Cancer research; Histone; Biochemistry; Gene","score_opus":0.009630478867627353,"score_gpt":0.2785078199228863,"score_spread":0.26887734105525896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999602199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955304,0.00019929458,0.00040501007,0.00040778588,0.000117646356,0.00017455558,0.00003370145,0.00001590256,0.0031156966],"genre_scores_gemma":[0.9985145,0.000040688185,0.0005073382,0.00030452505,0.00016482064,0.000046003435,0.00003834701,0.000042255648,0.00034152737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984409,0.00018043235,0.00027585687,0.0004334847,0.00035749903,0.00031180796],"domain_scores_gemma":[0.9988682,0.00011716232,0.00010258368,0.0006258698,0.00009184777,0.00019432447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005087793,0.00020905306,0.00027111944,0.00012121164,0.00008719034,0.000012578591,0.00020518957,0.00009473875,0.00005993121],"category_scores_gemma":[0.0009005995,0.00020331428,0.0001038793,0.00010502108,0.0003021158,0.000003680647,0.00011360256,0.00014585292,0.000020688309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027361087,0.00033792175,0.001125452,0.0001464156,0.000036821508,0.000015857095,0.00003087848,0.00010728023,0.9619274,0.000032767555,0.021417232,0.014548379],"study_design_scores_gemma":[0.000623895,0.0002751628,0.00041040155,0.000073037474,0.000019237046,0.000006040915,0.000011129134,0.0015994926,0.96958613,0.000007969938,0.02718395,0.00020357886],"about_ca_topic_score_codex":0.000053810967,"about_ca_topic_score_gemma":0.000014876135,"teacher_disagreement_score":0.014344799,"about_ca_system_score_codex":0.00004995745,"about_ca_system_score_gemma":0.000074675285,"threshold_uncertainty_score":0.8290916},"labels":[],"label_agreement":null},{"id":"W2022089207","doi":"10.1039/c4md00013g","title":"Synthesis and evaluation of linear CuAAC-oligomerized antifreeze neo-glycopeptides","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Blood Services","keywords":"Glycopeptide; Antifreeze; Monomer; Chemistry; Combinatorial chemistry; Triazole; Click chemistry; Stereochemistry; Biochemistry; Polymer; Organic chemistry; Antibiotics","score_opus":0.03182432218919951,"score_gpt":0.2957543656102202,"score_spread":0.2639300434210207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022089207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9667778,0.00015427326,0.00008210407,0.0003411336,0.000014637764,0.00006471362,0.000022362326,0.000055908076,0.032487065],"genre_scores_gemma":[0.9981793,0.000054436292,0.0009988153,0.000032685723,0.00014508652,0.000098023454,0.000034266934,0.000018495395,0.00043888687],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989642,0.000035308938,0.00028552272,0.0002482301,0.0003114671,0.00015529426],"domain_scores_gemma":[0.9986624,0.00044248524,0.00015193822,0.00051925005,0.00013910954,0.000084780724],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00058746466,0.00013907622,0.000246041,0.000023147979,0.00009713354,0.000014127834,0.00019210098,0.00010991101,0.0011684325],"category_scores_gemma":[0.00087555335,0.00013593683,0.00006293264,0.00010968874,0.00012821176,0.00004854577,0.000070701964,0.000116272655,0.000021559988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014219318,0.00007918483,0.0014086365,0.00014140423,0.00002904361,1.3045243e-7,0.00009817025,0.0000138079495,0.95807683,0.00013578642,0.00035248674,0.03965029],"study_design_scores_gemma":[0.00048709373,0.0000041445273,0.0004308849,0.00007082465,0.00012539593,0.0000053356734,0.00008929714,0.0064662294,0.98067296,0.00048343747,0.011022863,0.00014155303],"about_ca_topic_score_codex":0.00003662964,"about_ca_topic_score_gemma":0.0000057898396,"teacher_disagreement_score":0.03950874,"about_ca_system_score_codex":0.000022131871,"about_ca_system_score_gemma":0.000030068193,"threshold_uncertainty_score":0.99974465},"labels":[],"label_agreement":null},{"id":"W2022856958","doi":"10.1039/c4md00063c","title":"Design of glycosyltransferase inhibitors targeting human<i>O</i>-GlcNAc transferase (OGT)","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Burnaby Hospital; Simon Fraser University","funders":"Université Claude Bernard Lyon 1; Centre National de la Recherche Scientifique","keywords":"Glycosyltransferase; Transferase; Biochemistry; Chemistry; Computational biology; Enzyme; Biology","score_opus":0.015138429231485184,"score_gpt":0.2660942009325127,"score_spread":0.2509557717010275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022856958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.865773,0.00030427368,0.13049278,0.00031303265,0.000103578655,0.0005288499,0.000014360388,0.000036700047,0.0024334004],"genre_scores_gemma":[0.99657923,0.00005251609,0.0023615193,0.00017862469,0.00022749553,0.000050354647,0.00015206168,0.000041974887,0.00035620955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981666,0.00029021257,0.00042430143,0.0003872239,0.00034518057,0.00038643164],"domain_scores_gemma":[0.99909747,0.000050260347,0.000060479724,0.00045710272,0.00016026205,0.00017444714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008978184,0.00022056454,0.00025389172,0.00009721769,0.00015057385,0.000022583006,0.00031645742,0.00019275726,0.00018810653],"category_scores_gemma":[0.00021748258,0.00021130485,0.00013962846,0.00017783509,0.000136246,0.0000073635533,0.000055369444,0.00019555839,0.00002373804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017802232,0.0001257201,0.00057112856,0.00005930791,0.000031082756,0.0000023446519,0.00009422955,0.00031881235,0.99337983,0.00018417291,0.0020680123,0.002987323],"study_design_scores_gemma":[0.0011887947,0.0006048646,0.00012950209,0.000023303708,0.000012674627,0.000004388584,0.000037542697,0.0004847409,0.97092324,0.00012323994,0.026231427,0.00023629169],"about_ca_topic_score_codex":0.000048585072,"about_ca_topic_score_gemma":0.000017495076,"teacher_disagreement_score":0.13080622,"about_ca_system_score_codex":0.000014191504,"about_ca_system_score_gemma":0.000063755644,"threshold_uncertainty_score":0.86167616},"labels":[],"label_agreement":null},{"id":"W2032915605","doi":"10.1039/c1md00195g","title":"Structure–activity relationships of methyl-lysine reader antagonists","year":2011,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium; Toronto Public Health","funders":"","keywords":"Lysine; Computational biology; Stereochemistry; Chemistry; Biology; Biochemistry; Amino acid","score_opus":0.04852003140383111,"score_gpt":0.25513788232367296,"score_spread":0.20661785091984186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032915605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925057,0.00019694597,0.0014280289,0.00015486318,0.00011751406,0.000116171,0.000022762251,0.000013935145,0.005444037],"genre_scores_gemma":[0.995002,0.000019304112,0.0041660727,0.000059086688,0.000082687,0.0000059836602,0.000078107805,0.000013570138,0.00057323265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993093,0.00010227175,0.00016598584,0.00018969504,0.000108589054,0.00012417133],"domain_scores_gemma":[0.9993684,0.000010288527,0.0001136972,0.000377669,0.00007240169,0.000057542646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001792111,0.00010631229,0.00012445201,0.000039979812,0.000060426424,0.0000046756513,0.00014102826,0.0001403529,0.0001524097],"category_scores_gemma":[0.00017034668,0.00009610569,0.00006170728,0.00010017399,0.000091469905,0.000005926098,0.00006252476,0.00012690264,0.000006710275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005431399,0.00005812492,0.009537766,0.000012070309,0.000032485557,6.01885e-7,0.00011261694,5.725747e-7,0.9864123,0.00032953007,0.0015955095,0.0018541152],"study_design_scores_gemma":[0.0002247569,0.00006849649,0.021543194,0.0000053879844,0.000013235323,0.0000047440735,0.000031052197,0.0000103936945,0.9697902,0.00034774217,0.007853606,0.000107156906],"about_ca_topic_score_codex":0.00004999383,"about_ca_topic_score_gemma":0.00003523849,"teacher_disagreement_score":0.016622059,"about_ca_system_score_codex":0.0000082545685,"about_ca_system_score_gemma":0.00003540078,"threshold_uncertainty_score":0.39190763},"labels":[],"label_agreement":null},{"id":"W2033043921","doi":"10.1039/c4md00174e","title":"Synthesis, complex stability and small animal PET imaging of a novel <sup>64</sup>Cu-labelled cryptand molecule","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cryptand; Radiosynthesis; Chemistry; Molecule; Tris; Radiochemistry; Nuclear medicine; Organic chemistry; Positron emission tomography; Biochemistry","score_opus":0.054065678515271165,"score_gpt":0.30628453764210106,"score_spread":0.2522188591268299,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033043921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98471546,0.00017263209,0.002077036,0.0030653812,0.0000058492383,0.00026911107,0.000039529365,0.000058026304,0.009596995],"genre_scores_gemma":[0.9923405,0.000016470445,0.007094491,0.00033693694,0.00007552384,0.000046181565,0.000022145878,0.000021414216,0.0000463251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988387,0.000042927866,0.0003356276,0.00033593326,0.00018484733,0.00026194984],"domain_scores_gemma":[0.9987027,0.000415995,0.00008150515,0.0004447204,0.000098022334,0.0002570627],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003851215,0.00018308655,0.00041254115,0.000029241406,0.00009365627,0.000015403106,0.000139469,0.000046574645,0.0003544602],"category_scores_gemma":[0.0004496384,0.00016643759,0.000078036785,0.00013917658,0.00030591484,0.000033516593,0.000086095344,0.00022492325,0.000005515269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017626723,0.0005802939,0.009833648,0.00042476924,0.00004483342,0.000005041338,0.00015051506,0.0000032259384,0.98688734,0.0005166477,0.0003307486,0.0010467023],"study_design_scores_gemma":[0.0024557034,0.000057806104,0.008508118,0.00009176415,0.00022395868,0.00014028428,0.00020709552,0.08006762,0.9026252,0.00008074542,0.005318064,0.00022362274],"about_ca_topic_score_codex":0.000020530175,"about_ca_topic_score_gemma":0.0000012290794,"teacher_disagreement_score":0.08426209,"about_ca_system_score_codex":0.00003527156,"about_ca_system_score_gemma":0.000036433532,"threshold_uncertainty_score":0.6787128},"labels":[],"label_agreement":null},{"id":"W2037292620","doi":"10.1039/c5md00079c","title":"Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Helmholtz-Zentrum Dresden-Rossendorf; China Scholarship Council; National Natural Science Foundation of China","keywords":"Indole test; Sigma; Ligand (biochemistry); DU145; Chemistry; Sigma receptor; Stereochemistry; Receptor; Cell cycle checkpoint; Cell cycle; Cell; Cell biology; Biology; Biochemistry; Genetics; Physics; Cancer cell; Cancer","score_opus":0.046330717489451334,"score_gpt":0.29025220494710907,"score_spread":0.24392148745765774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037292620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917871,0.00020630729,0.006777571,0.0004198638,0.00021481086,0.00025759902,0.00007129479,0.00003201175,0.00023345184],"genre_scores_gemma":[0.99630386,0.0000130748285,0.0028824066,0.00041962074,0.00021356637,0.00004781418,0.000058715013,0.00002083504,0.00004008639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989185,0.0001249249,0.00014129806,0.00037901528,0.00017808158,0.0002582332],"domain_scores_gemma":[0.9991329,0.00018702075,0.00009404744,0.0002130345,0.00009407805,0.00027892232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041812268,0.00021726615,0.0002231386,0.00003817938,0.00012623561,0.00003824199,0.00015464264,0.00026647217,0.000039582937],"category_scores_gemma":[0.0014668354,0.00018114007,0.000058016118,0.000107244254,0.00009685239,0.00001033301,0.000116426025,0.00023460377,0.0000074801897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032456112,0.00012759869,0.0032568604,0.000017630153,0.000029549992,0.0000010314957,0.00004129412,0.000033500874,0.9925897,0.00014067013,0.0017098143,0.001727774],"study_design_scores_gemma":[0.0010497628,0.0002737832,0.0035541041,0.000015635364,0.000024445735,0.0000048337565,0.000025525303,0.00026732247,0.9909328,0.0003309928,0.003284344,0.00023643792],"about_ca_topic_score_codex":0.000013871476,"about_ca_topic_score_gemma":0.000015371188,"teacher_disagreement_score":0.004516791,"about_ca_system_score_codex":0.00003195167,"about_ca_system_score_gemma":0.00012540344,"threshold_uncertainty_score":0.7386678},"labels":[],"label_agreement":null},{"id":"W2041438017","doi":"10.1039/c4md00317a","title":"Structure–activity relationship studies of SETD8 inhibitors","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium; Toronto Public Health","funders":"National Institute of General Medical Sciences; National Institutes of Health; Ontario Ministry of Economic Development and Innovation; Eli Lilly Canada; Wellcome Trust; Novartis Foundation","keywords":"Substrate (aquarium); Computational biology; Chemistry; Stereochemistry; Biology; Ecology","score_opus":0.031701715216422406,"score_gpt":0.29079996247585904,"score_spread":0.25909824725943664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041438017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964806,0.00046757734,0.00031502193,0.00015719047,0.00014968873,0.000097944256,0.000016931774,0.0000120318655,0.0023030303],"genre_scores_gemma":[0.99863976,0.000016870854,0.00071857095,0.00008226905,0.00022026245,0.000008811093,0.000028252996,0.000012516954,0.00027268115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932635,0.000112177535,0.00014238202,0.00018065999,0.000106187836,0.00013224203],"domain_scores_gemma":[0.9994235,0.000058187445,0.00009492919,0.0003060439,0.00007307211,0.00004427183],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026024246,0.00010786074,0.00015165374,0.000028176819,0.000064915286,0.000004940789,0.0001122128,0.000109860855,0.000016190661],"category_scores_gemma":[0.00055363897,0.000095060466,0.00006192154,0.000067405,0.0001060557,0.0000027018348,0.00009592524,0.00009643016,0.000004791941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032550746,0.000028598277,0.02330274,0.00006960455,0.00004797037,2.3806635e-7,0.00019166342,0.000011713271,0.9698409,0.0007004928,0.0016203829,0.0041531664],"study_design_scores_gemma":[0.00023803195,0.00012429,0.0060255914,0.000015511867,0.000011768748,0.000003103133,0.000060221388,0.000015978641,0.98352545,0.0015480223,0.008322035,0.000110004155],"about_ca_topic_score_codex":0.000005117273,"about_ca_topic_score_gemma":0.000019603094,"teacher_disagreement_score":0.017277148,"about_ca_system_score_codex":0.00000804502,"about_ca_system_score_gemma":0.00002095583,"threshold_uncertainty_score":0.38764533},"labels":[],"label_agreement":null},{"id":"W2045219910","doi":"10.1039/c3md00054k","title":"Bicycle synthesis through peptide macrocyclization using aziridine aldehydes followed by late stage disulfide bond installation","year":2013,"lang":"en","type":"article","venue":"MedChemComm","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Public Health","funders":"Québec Consortium for Drug Discovery","keywords":"Disulfide bond; Peptidomimetic; Aziridine; Combinatorial chemistry; Chemistry; Peptide; Organic chemistry; Biochemistry; Ring (chemistry)","score_opus":0.01172753592295029,"score_gpt":0.24724637276181163,"score_spread":0.23551883683886135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045219910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99263465,0.00039080254,0.0042348364,0.0004929169,0.00003196195,0.00016206453,0.000048460704,0.000029974854,0.0019743266],"genre_scores_gemma":[0.99528164,0.00017952647,0.0023704728,0.0002795746,0.00011388726,0.000038193935,0.0003430091,0.0000423062,0.0013514032],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871045,0.00005184998,0.00032992093,0.00040542404,0.00019609046,0.0003062684],"domain_scores_gemma":[0.99924797,0.000047562706,0.00015952381,0.00037437963,0.00007068607,0.00009990124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012112353,0.00022969331,0.00025945008,0.00003206604,0.00014243604,0.00008049675,0.00019256299,0.00017002983,0.00033071448],"category_scores_gemma":[0.00022047234,0.00020829533,0.00018157219,0.00017539017,0.00006938055,0.000027915561,0.00012466095,0.00007473908,0.00003093736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013735892,0.000070818714,0.0046299295,0.000016503187,0.00008162097,5.6596855e-7,0.000028446693,0.00015343569,0.987215,0.000012265419,0.006772963,0.0010047514],"study_design_scores_gemma":[0.00021177182,0.000016284464,0.0005736928,0.000025476958,0.00006851668,0.0000010848858,0.000068709865,0.0020156885,0.9659886,0.00008703209,0.030665964,0.00027721692],"about_ca_topic_score_codex":0.00058499945,"about_ca_topic_score_gemma":0.000055666547,"teacher_disagreement_score":0.023893,"about_ca_system_score_codex":0.000041727573,"about_ca_system_score_gemma":0.000018274639,"threshold_uncertainty_score":0.8494037},"labels":[],"label_agreement":null},{"id":"W2047059468","doi":"10.1039/c2md20161e","title":"Analogues of the HIV-Tat peptide containing Nη-modified arginines as potent inhibitors of protein arginine N-methyltransferases","year":2012,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of British Columbia","funders":"","keywords":"Peptide; Arginine; Methylation; Methyltransferase; Biochemistry; Enzyme; Protein arginine methyltransferase 5; Chemistry; Biology; Amino acid; Gene","score_opus":0.010378795990406092,"score_gpt":0.24201946473008812,"score_spread":0.23164066873968203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047059468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99510145,0.0024554725,0.00042151113,0.00044460807,0.00018940133,0.0003766615,0.000036575977,0.000011969926,0.0009623654],"genre_scores_gemma":[0.99861187,0.000056991226,0.00033876437,0.00005040551,0.00029582318,0.000038321094,0.00013517746,0.000026590591,0.00044603535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987825,0.00011773591,0.00039817244,0.00019923555,0.00023725195,0.00026510388],"domain_scores_gemma":[0.99912095,0.000028137722,0.0002189047,0.00043058544,0.00012549039,0.00007593238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003274965,0.00018384345,0.0002580155,0.00005727627,0.000055005625,0.0000055265014,0.00020732285,0.0001585324,0.000019793108],"category_scores_gemma":[0.0001698241,0.00014197298,0.00018245727,0.00017829909,0.00019253242,0.000008905218,0.00008602912,0.00011782551,0.00000357545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000166574,0.00009856023,0.009964263,0.000051276023,0.000101317724,2.509476e-7,0.00032623924,0.00046564933,0.98625636,0.00017377723,0.0004247112,0.0019710385],"study_design_scores_gemma":[0.000657038,0.0001888413,0.00899458,0.00010247113,0.00005117617,0.000008168912,0.00024348625,0.000041737672,0.985142,0.000050016657,0.004364938,0.00015557908],"about_ca_topic_score_codex":0.00010619363,"about_ca_topic_score_gemma":0.00004059219,"teacher_disagreement_score":0.003940227,"about_ca_system_score_codex":0.00002342601,"about_ca_system_score_gemma":0.00008222181,"threshold_uncertainty_score":0.57894903},"labels":[],"label_agreement":null},{"id":"W2048049311","doi":"10.1039/c1md00199j","title":"Development of second generation epigenetic agents","year":2011,"lang":"en","type":"article","venue":"MedChemComm","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Epigenetics; Computational biology; Biology; Computer science; Genetics; Gene","score_opus":0.06943027545734108,"score_gpt":0.27227529898821534,"score_spread":0.20284502353087425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048049311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98610556,0.0006358835,0.0045530554,0.0000048626484,0.00012967046,0.00009656822,0.0000034229072,0.0000049749406,0.008466022],"genre_scores_gemma":[0.97488004,0.000047049423,0.024282241,0.000036216545,0.00008415841,0.000014590895,0.00010444253,0.000014526827,0.0005367274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992929,0.00003052747,0.0002587853,0.00018468725,0.000103028644,0.00013007084],"domain_scores_gemma":[0.99953127,0.0000025232475,0.00009450618,0.0002505902,0.00006628839,0.00005480779],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019297255,0.00009719745,0.00009525226,0.00003365716,0.000048388018,0.000004303032,0.00012273063,0.00009230336,0.00029533892],"category_scores_gemma":[0.000022234843,0.0000968834,0.00004183429,0.000048767448,0.000029531833,0.000001809411,0.000048330006,0.000033594286,0.000014043419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008613675,0.000059454615,0.003137103,0.000011913113,0.000025966825,3.2858594e-7,0.0005410487,0.000003548795,0.9842848,0.000026128439,0.00016584583,0.011735204],"study_design_scores_gemma":[0.0001800775,0.00005657686,0.028201658,0.0000034060963,0.0000066200887,4.173198e-7,0.000028388647,0.000026441063,0.94003934,0.00005224263,0.0312983,0.00010654203],"about_ca_topic_score_codex":0.0000039081783,"about_ca_topic_score_gemma":0.00012228316,"teacher_disagreement_score":0.044245515,"about_ca_system_score_codex":0.000008052158,"about_ca_system_score_gemma":0.00005442564,"threshold_uncertainty_score":0.39507902},"labels":[],"label_agreement":null},{"id":"W2055820111","doi":"10.1039/c1md00128k","title":"A pseudorotaxane umbrella thread with chloride transmembrane transport properties","year":2011,"lang":"en","type":"article","venue":"MedChemComm","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Amphiphile; Thread (computing); Transmembrane protein; Chemistry; Cholic acid; Chloride; Membrane; Biophysics; Computer science; Organic chemistry; Biochemistry; Polymer; Copolymer; Biology","score_opus":0.03719556060642571,"score_gpt":0.19350971400171874,"score_spread":0.15631415339529303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055820111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92971283,0.00022017768,0.00065552053,0.00010150064,0.000057783516,0.00010967342,0.0000052665237,0.0002128168,0.068924405],"genre_scores_gemma":[0.99414015,0.00007096785,0.0006101294,0.000090034824,0.00009296785,0.000055584904,0.000011406534,0.000057548452,0.0048711994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877954,0.000012187742,0.00025428616,0.0003451431,0.00028742486,0.00032144404],"domain_scores_gemma":[0.99926716,0.000007456369,0.00007475147,0.00046225035,0.00005730381,0.00013109455],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008963381,0.00025307285,0.00026387168,0.000043244843,0.00009781451,0.000013429834,0.00021277217,0.00013871277,0.0023810447],"category_scores_gemma":[0.0000067433425,0.00018694943,0.00011210129,0.00012722422,0.00010944062,0.00008985955,0.000009624688,0.00026218116,0.000057714544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018126359,0.00041437897,0.0028883724,0.0006314015,0.00020075531,0.0002568842,0.0043795286,0.000015552005,0.98041594,0.00019174491,0.000101995676,0.008690836],"study_design_scores_gemma":[0.00082113204,0.00008901454,0.000410352,0.000117781485,0.00006722312,0.00015186823,0.00019674544,0.00006526285,0.9896785,0.000051291627,0.008043219,0.00030758063],"about_ca_topic_score_codex":0.00037191215,"about_ca_topic_score_gemma":0.0001306185,"teacher_disagreement_score":0.06442731,"about_ca_system_score_codex":0.00002633854,"about_ca_system_score_gemma":0.00003373207,"threshold_uncertainty_score":0.9985309},"labels":[],"label_agreement":null},{"id":"W2065196048","doi":"10.1039/c3md00053b","title":"<i>N</i>-substituted sultam carboxylic acids as novel glycogen synthase activators","year":2013,"lang":"en","type":"article","venue":"MedChemComm","topic":"Glycogen Storage Diseases and Myoclonus","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nutrasource","funders":"","keywords":"Chemistry; ATP synthase; Glycogen synthase; Carboxylic acid; Glycogen; Biochemistry; Enzyme","score_opus":0.012260114240491003,"score_gpt":0.25224341563278885,"score_spread":0.23998330139229784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065196048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9801535,0.0005257905,0.00014518648,0.0014718942,0.00041152665,0.0008962629,0.00004029867,0.00028671356,0.016068825],"genre_scores_gemma":[0.9944539,0.000035557143,0.0008126357,0.002075453,0.00036370003,0.00022297978,0.00016119167,0.00007528285,0.0017992648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979467,0.000028367938,0.00037409298,0.00050282246,0.00051554845,0.00063251733],"domain_scores_gemma":[0.9978828,0.000088973706,0.00011440876,0.0008416246,0.00025227503,0.00081991364],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000115552306,0.0003806026,0.0005219659,0.00014304822,0.0001498393,0.00006105783,0.0002587775,0.00020779346,0.002885836],"category_scores_gemma":[0.0004040247,0.00032383337,0.00027560312,0.0004338495,0.00014235896,0.00023420846,0.00011780916,0.0003393755,0.0015746665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063263794,0.0018965838,0.011254681,0.00027768716,0.00068413734,0.0022868635,0.00072000205,0.0000059693916,0.9441362,0.0007521313,0.019138996,0.01821408],"study_design_scores_gemma":[0.014316985,0.00071566174,0.03788246,0.00047333128,0.0013941393,0.0038228855,0.0016408227,0.0007248587,0.685069,0.00030997407,0.2517057,0.00194417],"about_ca_topic_score_codex":0.0016542353,"about_ca_topic_score_gemma":0.000010197717,"teacher_disagreement_score":0.2590672,"about_ca_system_score_codex":0.00014703053,"about_ca_system_score_gemma":0.0002504433,"threshold_uncertainty_score":0.9999214},"labels":[],"label_agreement":null},{"id":"W2066071173","doi":"10.1039/c4md00168k","title":"Conformational analysis of peramivir reveals critical differences between free and enzyme-bound states","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Glycomics Centre; University of Victoria; University of Alberta","funders":"Alberta Glycomics Centre; Canada Research Chairs; Michael Smith Health Research BC; University of Alberta; Cancer Research Society","keywords":"Chemistry; Enzyme; Biochemistry","score_opus":0.0750287183855995,"score_gpt":0.38850510938348626,"score_spread":0.31347639099788677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066071173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99314535,0.0005442646,0.0006294212,0.0023716162,0.000017242843,0.00013032812,0.00014815564,0.000025395202,0.0029882255],"genre_scores_gemma":[0.9984595,0.00008492936,0.00077023177,0.0003697578,0.000077049204,0.000015119818,0.00006579354,0.0000070892297,0.00015052503],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985388,0.000099469944,0.00037916604,0.00016394995,0.0005548945,0.0002637286],"domain_scores_gemma":[0.99741256,0.0017546916,0.00006342015,0.0003227116,0.0002917242,0.00015490018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065879733,0.00013060354,0.00064600696,0.00027659317,0.00011633592,0.000029731396,0.00014185284,0.00006528583,0.00022846054],"category_scores_gemma":[0.002732972,0.00009750472,0.00009442198,0.0003120938,0.0005837156,0.000098173296,0.0001671634,0.00018263557,0.000008748131],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007485969,0.000081106125,0.98296446,0.00037867125,0.0018178589,0.0000020408918,0.0018503715,0.0000032046905,0.0015981925,0.005351987,0.0022700583,0.0036072226],"study_design_scores_gemma":[0.00080610276,0.00021849573,0.9868941,0.000060706592,0.00091978983,0.0000014898933,0.00034533392,0.0021460364,0.0036629569,0.0029661758,0.0018556416,0.00012321875],"about_ca_topic_score_codex":0.00011290391,"about_ca_topic_score_gemma":0.00002829839,"teacher_disagreement_score":0.0053141536,"about_ca_system_score_codex":0.000027182668,"about_ca_system_score_gemma":0.000032423417,"threshold_uncertainty_score":0.39761272},"labels":[],"label_agreement":null},{"id":"W2066165562","doi":"10.1039/c5md00018a","title":"Exploring cinnamic acid scaffold: development of promising neuroprotective lipophilic antioxidants","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Insemination Center of Quebec","funders":"","keywords":"Neuroprotection; Cinnamic acid; Scaffold; Chemistry; Traditional medicine; Pharmacology; Biochemistry; Biology; Medicine; Biomedical engineering","score_opus":0.16842915374647965,"score_gpt":0.26748311194090224,"score_spread":0.09905395819442259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066165562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934586,0.00031841313,0.00033529446,0.00009478061,0.00015605442,0.000104435494,0.000005718917,0.00013564754,0.005391037],"genre_scores_gemma":[0.99546635,0.000023734643,0.004048979,0.000021402551,0.0001426549,0.00005064626,0.000006897864,0.000049691585,0.0001896343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99816895,0.00003024835,0.00051598274,0.00037921857,0.00049513555,0.000410443],"domain_scores_gemma":[0.99896294,0.000030228637,0.00020495843,0.00043257792,0.00013153201,0.00023777684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035317417,0.00025207692,0.00037410491,0.000097403754,0.000112823895,0.000029161758,0.00037001196,0.00009034217,0.00009315869],"category_scores_gemma":[0.00021149722,0.00023870342,0.00008594509,0.00025631502,0.00010370605,0.00025591408,0.00018281478,0.00024119696,0.00004908622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046765304,0.0001923715,0.0013652684,0.00020718688,0.0000519323,0.00002303318,0.0015990133,0.000007890244,0.95072716,0.000047505855,0.000051384282,0.045680482],"study_design_scores_gemma":[0.00081810745,0.000025179344,0.0024726146,0.00033573518,0.000014830549,0.00002289877,0.00041478916,0.00024762904,0.9933983,0.00014446974,0.0018302377,0.0002751867],"about_ca_topic_score_codex":0.000024391067,"about_ca_topic_score_gemma":0.000011361222,"teacher_disagreement_score":0.0454053,"about_ca_system_score_codex":0.00012051833,"about_ca_system_score_gemma":0.00018842757,"threshold_uncertainty_score":0.9734043},"labels":[],"label_agreement":null},{"id":"W2066287229","doi":"10.1039/c3md00197k","title":"The structure–activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface","year":2013,"lang":"en","type":"article","venue":"MedChemComm","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Structural Genomics Consortium; University of Toronto","funders":"National Institute of General Medical Sciences; Wellcome Trust","keywords":"Dimer; Chemistry; Ligand (biochemistry); Flexibility (engineering); Stereochemistry; Biochemistry; Receptor; Organic chemistry","score_opus":0.01729575601809304,"score_gpt":0.26274870344431983,"score_spread":0.24545294742622678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066287229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970948,0.0009594036,0.00053195155,0.00044773467,0.00016787485,0.00022667082,0.000010060156,0.000003006899,0.0005585057],"genre_scores_gemma":[0.9994424,0.000033775155,0.00019730917,0.000009880221,0.00005575012,0.0000063026914,0.000005491493,0.0000087341305,0.0002403539],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915236,0.00021942776,0.0002292655,0.00014827742,0.00013982975,0.00011081989],"domain_scores_gemma":[0.9989282,0.00009567159,0.00018895708,0.00061527576,0.00014282101,0.000029085722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035501266,0.00008898022,0.00009918981,0.000010374817,0.00011731722,0.000010803527,0.00023700662,0.00011559897,0.000020647534],"category_scores_gemma":[0.00044750152,0.000051249677,0.000083978855,0.00009039763,0.00020234083,0.000004207167,0.00015989748,0.00015143126,0.0000018449083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012497474,0.000025170326,0.029581742,0.000010574961,0.00002009597,5.35611e-9,0.00007849551,0.00009919881,0.96696484,0.000057587757,0.00025667145,0.0028931212],"study_design_scores_gemma":[0.000100666875,0.000037514674,0.084459946,0.0000075808152,0.000009113193,1.9887494e-7,0.00004667963,0.00009650796,0.91120255,0.00172128,0.0022650857,0.000052865722],"about_ca_topic_score_codex":0.00010556017,"about_ca_topic_score_gemma":0.00011690438,"teacher_disagreement_score":0.055762276,"about_ca_system_score_codex":0.000009820538,"about_ca_system_score_gemma":0.000035986184,"threshold_uncertainty_score":0.20899013},"labels":[],"label_agreement":null},{"id":"W2066820386","doi":"10.1039/c1md00206f","title":"Synthesis and activity of a novel diether phosphonoglycerol in phospholipase-resistant synthetic lipid:peptide lung surfactants","year":2011,"lang":"en","type":"article","venue":"MedChemComm","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"National Institute of Environmental Health Sciences; National Heart, Lung, and Blood Institute","keywords":"Pulmonary surfactant; Phosphatidylglycerol; Chemistry; Phospholipid; Peptide; POPC; Phospholipase; Phosphatidylcholine; Surface tension; Stereochemistry; Chromatography; Organic chemistry; Biochemistry; Membrane; Enzyme","score_opus":0.07283728163275215,"score_gpt":0.3324499242750209,"score_spread":0.25961264264226874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066820386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932324,0.0018089568,0.000053724616,0.000246264,0.00007040147,0.0007300179,0.000046410045,0.000041518062,0.0037702953],"genre_scores_gemma":[0.9979223,0.00033918506,0.0011250933,0.00015970052,0.000026449725,0.00011491538,0.0000010406145,0.00006363939,0.0002477008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976436,0.00012603529,0.0004986966,0.0004927643,0.00059516,0.0006437733],"domain_scores_gemma":[0.99796575,0.00060449523,0.00016585397,0.00071864255,0.00011618152,0.00042905268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010793625,0.00028043168,0.00072371424,0.00023171568,0.00006313451,0.000008973856,0.00022309729,0.00019361761,0.0005902962],"category_scores_gemma":[0.0012955887,0.0002446729,0.000098746714,0.00040824295,0.00031212953,0.00012315018,0.00017470782,0.00052615744,0.000018901239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024083138,0.0055399095,0.159655,0.008170935,0.00028700242,0.00048170172,0.004632774,0.0000020982566,0.66222924,0.00029745157,0.00031324214,0.1343075],"study_design_scores_gemma":[0.0027950243,0.00030962253,0.18271466,0.00088538765,0.000063966945,0.000023263754,0.00015353019,0.0006434854,0.81079614,0.000019665671,0.0013490878,0.0002461402],"about_ca_topic_score_codex":0.0029307161,"about_ca_topic_score_gemma":0.00036662578,"teacher_disagreement_score":0.14856692,"about_ca_system_score_codex":0.00023519223,"about_ca_system_score_gemma":0.00029237394,"threshold_uncertainty_score":0.9977471},"labels":[],"label_agreement":null},{"id":"W2077456875","doi":"10.1039/c3md00291h","title":"Discovery of BET bromodomain inhibitors and their role in target validation","year":2013,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Research and Innovation Foundation; Ontario Ministry of Research and Innovation; Wellcome Trust","keywords":"Bromodomain; Computational biology; Key (lock); Biology; Computer science; Biochemistry; Epigenetics; Gene; Ecology","score_opus":0.004504135138817877,"score_gpt":0.20021343687539397,"score_spread":0.1957093017365761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077456875","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976725,0.0004536369,0.0005807617,0.00025410653,0.00005026687,0.00019093277,0.0000098009705,0.0000052928817,0.00078270095],"genre_scores_gemma":[0.99898076,0.000039729774,0.00045902396,0.000078336336,0.00006985139,0.000033000753,0.00012284385,0.000010504146,0.00020592833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940634,0.000057773363,0.00018980695,0.00016513508,0.000063809806,0.00011713428],"domain_scores_gemma":[0.9996808,0.0000113779015,0.00006646671,0.00018057828,0.000028240913,0.00003252467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015396778,0.00009694344,0.000118508775,0.000046443172,0.000020036809,0.00002085766,0.0000824993,0.00009023695,0.000019838912],"category_scores_gemma":[0.00006295037,0.00008033308,0.000036234316,0.00006965536,0.00005970389,0.000018353756,0.000081436585,0.00005597476,0.0000038690737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008964856,0.000044131546,0.013441336,0.0000117420595,0.000007902746,1.1280151e-7,0.000098886965,0.0000037447724,0.9832345,0.00007041562,0.0011700713,0.0019081566],"study_design_scores_gemma":[0.00031025428,0.000060872804,0.005608536,0.000015308593,0.0000013448874,0.000001552066,0.00021037184,0.00006247909,0.9896856,0.0011424756,0.0028070658,0.000094170144],"about_ca_topic_score_codex":0.00010011292,"about_ca_topic_score_gemma":0.000014281802,"teacher_disagreement_score":0.007832801,"about_ca_system_score_codex":0.0000078362245,"about_ca_system_score_gemma":0.000018731354,"threshold_uncertainty_score":0.32758877},"labels":[],"label_agreement":null},{"id":"W2081485322","doi":"10.1039/c4md00209a","title":"Synthesis of 1-O-acetylbritannilactone analogues from Inula britannica and in vitro evaluation of their anticancer potential","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Sesquiterpenes and Asteraceae Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nutrasource","funders":"National Natural Science Foundation of China","keywords":"HeLa; In vitro; Ring (chemistry); Chemistry; Stereochemistry; Apoptosis; Biochemistry; Organic chemistry","score_opus":0.012827373962504187,"score_gpt":0.2638662128028463,"score_spread":0.2510388388403421,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081485322","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996581,0.0026427577,0.00013717185,0.00012950464,0.000047018348,0.000093313414,0.0000577213,0.000002247061,0.00030923742],"genre_scores_gemma":[0.9991922,0.00026122565,0.00035460969,0.00003763566,0.000073549716,0.000013459763,0.00005084931,0.000009592159,0.0000069208827],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991647,0.0001284287,0.00023295222,0.00020255067,0.00015684354,0.00011451828],"domain_scores_gemma":[0.999475,0.00005721895,0.000106875144,0.00022481878,0.000111010566,0.000025060717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000420604,0.00010374562,0.00025752687,0.00003571183,0.000019120509,0.00000582132,0.000098881625,0.000067022855,0.000014036594],"category_scores_gemma":[0.00017937567,0.00009086861,0.00005420295,0.00005800238,0.00011272531,0.0000043272166,0.000107826105,0.00003779886,3.331747e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012594956,0.000051240022,0.0068072528,0.000018015235,0.000063101186,1.6439904e-7,0.00013219252,0.000016879343,0.965697,0.00000213997,0.000038832295,0.027047243],"study_design_scores_gemma":[0.00049205596,0.00003973106,0.07844121,0.00004523809,0.00005779647,0.0000010327711,0.0002785161,0.00081550167,0.919398,0.00008165456,0.00025657864,0.00009264639],"about_ca_topic_score_codex":0.00013071249,"about_ca_topic_score_gemma":0.000075228956,"teacher_disagreement_score":0.07163396,"about_ca_system_score_codex":0.0000069970883,"about_ca_system_score_gemma":0.00001921875,"threshold_uncertainty_score":0.37055144},"labels":[],"label_agreement":null},{"id":"W2081973136","doi":"10.1039/c4md00255e","title":"Synthesis of α-brominated phosphonates and their application as phosphate bioisosteres","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and Reactivity of Sulfur-Containing Compounds","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta","keywords":"Phosphonate; Phosphate; Chemistry; Combinatorial chemistry; Stereochemistry; Organic chemistry","score_opus":0.006483684702448047,"score_gpt":0.2074164615804197,"score_spread":0.20093277687797167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081973136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9795365,0.0006882176,0.00012613492,0.0004816496,0.000034137196,0.00005604026,0.000009394121,0.000095738746,0.0189722],"genre_scores_gemma":[0.99923176,0.00009081941,0.00024143835,0.000051319563,0.00004825296,0.000041603445,0.000010119542,0.000030186211,0.00025453174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990671,0.000028175562,0.0002579447,0.00030203332,0.00013536068,0.00020935315],"domain_scores_gemma":[0.99819183,0.0010329366,0.00020508334,0.00042905228,0.000056222478,0.000084894906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000305339,0.00021168095,0.00039123616,0.000049023733,0.00009394844,0.00003092681,0.0002516991,0.00014288371,0.00017634475],"category_scores_gemma":[0.0002891362,0.00016729264,0.000084603744,0.00007875849,0.0001754733,0.000078669524,0.00009397702,0.000119643264,0.00002083689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046073546,0.00011683758,0.0045199795,0.00010207623,0.000069362184,4.2131867e-7,0.00041599214,4.2995978e-7,0.6711648,0.0002555681,0.000074194824,0.32323423],"study_design_scores_gemma":[0.00025829702,0.000021857732,0.0019665123,0.00012830652,0.000028635095,0.000009924607,0.000492091,0.0008212851,0.9820609,0.0010303124,0.0129855415,0.0001963436],"about_ca_topic_score_codex":0.00042025256,"about_ca_topic_score_gemma":0.00001395296,"teacher_disagreement_score":0.3230379,"about_ca_system_score_codex":0.000024584762,"about_ca_system_score_gemma":0.000015823725,"threshold_uncertainty_score":0.6821996},"labels":[],"label_agreement":null},{"id":"W2083926784","doi":"10.1039/c2md20014g","title":"The solid phase supported peptide synthesis of analogues of the lantibiotic lactocin S","year":2012,"lang":"en","type":"article","venue":"MedChemComm","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Lantibiotics; Lactobacillus sakei; Peptide; Combinatorial chemistry; Antimicrobial; Chemistry; Solid-phase synthesis; Peptide synthesis; Biochemistry; Stereochemistry; Nisin; Lactobacillus; Organic chemistry","score_opus":0.02307987497922096,"score_gpt":0.27109593995855324,"score_spread":0.2480160649793323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083926784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965079,0.00018599004,0.0000012576188,0.001205119,0.00009047911,0.00011605019,0.00005831956,0.000010396461,0.0018244876],"genre_scores_gemma":[0.99965966,0.00004825874,0.000016566577,0.000051672243,0.00006607873,0.000002106655,0.000009974233,7.5103816e-7,0.000144925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924046,0.00009142436,0.00021604064,0.000074734875,0.00014784855,0.00022949024],"domain_scores_gemma":[0.9992712,0.00037595825,0.00015470457,0.00010919481,0.000038760274,0.000050150084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045025683,0.000081384445,0.00015080503,0.0000047099284,0.00013466498,0.000009909682,0.00036235817,0.000052598287,0.00008677002],"category_scores_gemma":[0.00015345469,0.00002021098,0.0001175873,0.00018537653,0.00015308893,0.00003708932,0.00009482159,0.00008119244,0.000005522561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030299765,0.00040802392,0.040207088,0.000012354374,0.00005835318,2.3595994e-7,0.00014116208,3.7714761e-7,0.9394117,0.0008090009,0.0013790507,0.017542332],"study_design_scores_gemma":[0.000096578515,0.0000816959,0.16534163,0.000030244408,0.00003897659,0.0000022668958,0.00033103427,0.000026040354,0.8288709,0.00013357718,0.004977108,0.000069961556],"about_ca_topic_score_codex":0.00007383664,"about_ca_topic_score_gemma":0.00010460279,"teacher_disagreement_score":0.12513454,"about_ca_system_score_codex":0.0000074412674,"about_ca_system_score_gemma":0.0000053901326,"threshold_uncertainty_score":0.103574775},"labels":[],"label_agreement":null},{"id":"W2092628558","doi":"10.1039/c3md00293d","title":"Biologically active binaphthol-scaffolded imidazolium salts","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Nanotechnology; Combinatorial chemistry; Materials science","score_opus":0.007912758309142355,"score_gpt":0.22040874846229883,"score_spread":0.21249599015315648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092628558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97402674,0.00021564342,0.00087275385,0.0009009267,0.00027795814,0.00012161846,0.000021634909,0.000051165338,0.023511581],"genre_scores_gemma":[0.9965453,0.00009945547,0.000584496,0.0008982423,0.00079701433,0.000034498706,0.00008772291,0.00002945188,0.00092380506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876237,0.000102849204,0.00021132878,0.00041597837,0.00013718921,0.00037025695],"domain_scores_gemma":[0.99921083,0.000051727347,0.00010368817,0.0004468675,0.000072664996,0.000114207796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023725742,0.00025012068,0.00026425076,0.00004386734,0.00014136563,0.000038667316,0.0003087883,0.0002039908,0.00009401878],"category_scores_gemma":[0.00019042025,0.00019049284,0.00016491713,0.000088481596,0.0001290601,0.000006829066,0.0001684496,0.000105965446,0.00005111236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012990774,0.00014972998,0.0018011227,0.000018978182,0.000052940173,0.000001480747,0.000044982535,0.000008036201,0.97154075,0.0008915156,0.004671363,0.020689178],"study_design_scores_gemma":[0.00049116067,0.00024220833,0.011787877,0.000017676446,0.000019236237,0.0000138135665,0.000107620945,0.00006364667,0.7436328,0.0006653671,0.24258825,0.0003703548],"about_ca_topic_score_codex":0.000019725823,"about_ca_topic_score_gemma":0.00001905542,"teacher_disagreement_score":0.23791689,"about_ca_system_score_codex":0.000010918267,"about_ca_system_score_gemma":0.000028488495,"threshold_uncertainty_score":0.77680725},"labels":[],"label_agreement":null},{"id":"W2093289213","doi":"10.1039/c4md00268g","title":"Can we use the epigenetic bioactivity of caloric restriction and phytochemicals to promote healthy ageing?","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Epigenetics; Caloric theory; Ageing; Biology; Healthy ageing; Computational biology; Genetics; Endocrinology; Gene","score_opus":0.01561457064920685,"score_gpt":0.24711409036896181,"score_spread":0.23149951971975496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093289213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98847,0.00039846264,0.0074819904,0.0030977565,0.0001367728,0.00032826586,0.00001449972,0.000013283584,0.000058951962],"genre_scores_gemma":[0.99684036,0.0005050618,0.0016270364,0.0006674946,0.00019335044,0.00002433825,0.00001818715,0.000025082096,0.00009911141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886256,0.00012758306,0.00023051072,0.00034875327,0.00015997543,0.0002705879],"domain_scores_gemma":[0.99902916,0.00004451159,0.00010939092,0.0005801397,0.000077060504,0.000159726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032682013,0.00017099098,0.0002006993,0.00004277939,0.000111753216,0.000027360276,0.00021163555,0.00013566723,0.000003628599],"category_scores_gemma":[0.00028729148,0.00013797493,0.000054614815,0.0001340878,0.00011716049,0.000003287214,0.00016293059,0.0001311816,0.0000025465863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052586263,0.00009563775,0.005177797,0.000062397405,0.000031022362,6.586768e-7,0.00068141375,0.00007946943,0.98521,0.000052589126,0.0008595424,0.007696867],"study_design_scores_gemma":[0.00035767528,0.00057770975,0.02221592,0.000022301343,0.000038727438,0.000007719311,0.000055184304,0.00023953702,0.9526378,0.00064317574,0.022968236,0.00023601933],"about_ca_topic_score_codex":0.00036674127,"about_ca_topic_score_gemma":0.0002649502,"teacher_disagreement_score":0.032572225,"about_ca_system_score_codex":0.000017458133,"about_ca_system_score_gemma":0.000040118066,"threshold_uncertainty_score":0.56264544},"labels":[],"label_agreement":null},{"id":"W2106471696","doi":"10.1039/c5md00189g","title":"Enhanced in vitro and in vivo uptake of a hydrophobic model drug coumarin-6 in the presence of cucurbit[7]uril","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Supramolecular Chemistry and Complexes","field":"Chemistry","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Universidade de Macau","keywords":"Coumarin; In vivo; In vitro; Zebrafish; Chemistry; Biochemistry; Biology; Genetics; Gene; Organic chemistry","score_opus":0.02016113538519724,"score_gpt":0.24376133065605965,"score_spread":0.22360019527086242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106471696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845411,0.00042279597,0.000016065307,0.000088653804,0.000010589189,0.000077410456,0.000013108911,0.000008154654,0.014822125],"genre_scores_gemma":[0.9993084,0.000023082126,0.0002811055,0.000035933233,0.000011976689,0.00004333461,0.0000070836336,0.000011727348,0.00027735165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987854,0.000041965923,0.0004213723,0.00024181316,0.00028457315,0.00022490202],"domain_scores_gemma":[0.9991876,0.00014209564,0.0001132363,0.00047087937,0.000034178927,0.00005204279],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039917097,0.0001551056,0.00031792233,0.000050428935,0.0000106104935,0.000009205531,0.00044028976,0.00009073938,0.000039474864],"category_scores_gemma":[0.00013805066,0.00013453557,0.000043868116,0.00023723122,0.00013757363,0.000062030565,0.00014025098,0.00027463856,5.847442e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021160046,0.00022174904,0.001390096,0.00017288156,0.0000059885774,0.00001533032,0.0046772,0.0005368711,0.99242085,0.00002384774,0.000074177275,0.00024941616],"study_design_scores_gemma":[0.0011292096,0.0000061234273,0.000070154936,0.00010886042,0.0000057480615,0.0000063085104,0.0013918837,0.019825341,0.9760216,0.0011940887,0.000120000586,0.00012067824],"about_ca_topic_score_codex":0.00037674,"about_ca_topic_score_gemma":0.0002111952,"teacher_disagreement_score":0.01928847,"about_ca_system_score_codex":0.00004207136,"about_ca_system_score_gemma":0.000091721384,"threshold_uncertainty_score":0.5486201},"labels":[],"label_agreement":null},{"id":"W2111977276","doi":"10.1039/c4md00274a","title":"Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium; Toronto Public Health","funders":"Engineering and Physical Sciences Research Council; European Commission; Wellcome Trust; Genome Canada","keywords":"Chemotype; Quinoline; Identification (biology); Chemistry; Combinatorial chemistry; Computational biology; Stereochemistry; Biology; Organic chemistry; Botany; Chromatography","score_opus":0.009288568440264799,"score_gpt":0.28958665478721235,"score_spread":0.28029808634694753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111977276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891573,0.0004666432,0.007276478,0.00042147198,0.00008070282,0.00014104828,0.0000060255793,0.0000141606415,0.0024361263],"genre_scores_gemma":[0.99756277,0.00006362351,0.0007394191,0.00018715701,0.00018468512,0.000022577755,0.00011074846,0.000020975302,0.001108034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988163,0.00012343097,0.000305824,0.00030943673,0.00022501347,0.00021996738],"domain_scores_gemma":[0.9991427,0.000026893587,0.000114823604,0.00046897234,0.00014493783,0.0001016822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043858358,0.00013339361,0.000160683,0.00005409977,0.00004561919,0.000013657983,0.000281773,0.00016318505,0.000032388398],"category_scores_gemma":[0.00066573604,0.00012252844,0.000107725944,0.00014238623,0.00019018269,0.0000033546373,0.0001885846,0.00011092947,0.000028842742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003751744,0.00007879971,0.000492081,0.000035368466,0.000029409986,4.0455475e-7,0.000030528892,0.0000022760287,0.99010974,0.00034910254,0.001027226,0.007807529],"study_design_scores_gemma":[0.00029944998,0.00014853729,0.00087220065,0.000011957413,0.000009434959,0.0000048407364,0.000028261638,0.00005588204,0.9743119,0.00045074904,0.023672452,0.00013436137],"about_ca_topic_score_codex":0.000017486454,"about_ca_topic_score_gemma":0.0000029806565,"teacher_disagreement_score":0.022645228,"about_ca_system_score_codex":0.000007313549,"about_ca_system_score_gemma":0.00003623561,"threshold_uncertainty_score":0.49965647},"labels":[],"label_agreement":null},{"id":"W2115605147","doi":"10.1039/c4md00124a","title":"Thiazole-based aminopyrimidines and N-phenylpyrazolines as potent antimicrobial agents: synthesis and biological evaluation","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Antimicrobial; Thiazole; Combinatorial chemistry; Chemistry; Traditional medicine; Pharmacology; Medicine; Biology; Microbiology; Stereochemistry","score_opus":0.04862394059879185,"score_gpt":0.27238472466500535,"score_spread":0.2237607840662135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115605147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99374074,0.00013436771,0.00006545432,0.0022497848,0.000055049837,0.00010034338,0.000016422788,0.00009164785,0.0035461886],"genre_scores_gemma":[0.99842924,0.0001067429,0.00047953965,0.0006497106,0.00021440537,0.000047582034,0.000025856365,0.000012547061,0.00003435695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868935,0.00013388303,0.0002421408,0.00045873114,0.00021066915,0.0002652363],"domain_scores_gemma":[0.99871755,0.0007150711,0.00011650927,0.00024950245,0.00007746918,0.00012387538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007109889,0.00024734717,0.00034796057,0.000035777935,0.000165125,0.0000643018,0.00015628184,0.00025252483,0.0008287893],"category_scores_gemma":[0.0017375859,0.0001637891,0.00007634389,0.00005708851,0.00027810468,0.0000573323,0.00012054122,0.00013968567,0.00002027863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001759186,0.00041584382,0.060844913,0.00013384013,0.000057669728,0.000003490667,0.000045395278,0.0000071766895,0.6865474,0.00016458312,0.00066938554,0.2509344],"study_design_scores_gemma":[0.0006083939,0.000056188463,0.043835223,0.00008563522,0.00009902378,0.00001847574,0.000055436714,0.006020119,0.9432552,0.0007387777,0.0048721875,0.00035537855],"about_ca_topic_score_codex":0.0000545364,"about_ca_topic_score_gemma":0.0000058486808,"teacher_disagreement_score":0.2567078,"about_ca_system_score_codex":0.000030857645,"about_ca_system_score_gemma":0.000017789036,"threshold_uncertainty_score":0.9074662},"labels":[],"label_agreement":null},{"id":"W2133615228","doi":"10.1039/c3md00285c","title":"The structure based design of dual HDAC/BET inhibitors as novel epigenetic probes","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"","keywords":"Epigenetics; Dual (grammatical number); Computational biology; Chemistry; Biology; Biochemistry; Gene; Philosophy","score_opus":0.008878804941862103,"score_gpt":0.2253739976941166,"score_spread":0.21649519275225448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133615228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.931681,0.0009381975,0.062743224,0.0017252864,0.00060969,0.0008800726,0.000035538418,0.00003996118,0.0013470745],"genre_scores_gemma":[0.99509865,0.0000200794,0.003751844,0.0003485157,0.00027152762,0.000020872578,0.0000663158,0.000024529349,0.00039763548],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890214,0.00013158907,0.00027386475,0.00024877058,0.00021798711,0.00022565147],"domain_scores_gemma":[0.999124,0.00006372892,0.00014343883,0.000486952,0.00010397436,0.0000779302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003764719,0.00016950945,0.00014280698,0.000031876534,0.00013863864,0.000027661488,0.000261121,0.00015962996,0.000032744592],"category_scores_gemma":[0.00045120722,0.00011963749,0.00007921686,0.0001009638,0.00017173727,0.000003255722,0.00008273471,0.00011040668,0.0000068846384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053492036,0.000044180368,0.0002990237,0.000015800662,0.000021688067,1.974839e-7,0.000024059833,0.0002619567,0.99189883,0.00025249165,0.0035153343,0.003612923],"study_design_scores_gemma":[0.0005096839,0.00027502555,0.00026132684,0.00001600343,0.000011343505,0.000003916305,0.000024684774,0.0005938277,0.9438546,0.0002703355,0.05403324,0.00014607041],"about_ca_topic_score_codex":0.00001369551,"about_ca_topic_score_gemma":0.0000152113635,"teacher_disagreement_score":0.063417725,"about_ca_system_score_codex":0.000009766514,"about_ca_system_score_gemma":0.00010259754,"threshold_uncertainty_score":0.48786753},"labels":[],"label_agreement":null},{"id":"W2133978559","doi":"10.1039/c5md00081e","title":"Identification of a novel class of autotaxin inhibitors through cross-screening","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cystic Fibrosis Canada","funders":"","keywords":"Autotaxin; Identification (biology); Computational biology; Class (philosophy); Computer science; Biology; Artificial intelligence; Biochemistry; Lysophosphatidic acid; Botany; Receptor","score_opus":0.03907848823655367,"score_gpt":0.31138139344383975,"score_spread":0.27230290520728606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133978559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96635693,0.0007935128,0.03187097,0.00004712663,0.0002545369,0.00008844324,0.000021668524,0.000009529194,0.0005572655],"genre_scores_gemma":[0.9954889,0.00001772476,0.003907129,0.000049190727,0.00023994569,0.000007861693,0.00005193054,0.000016774862,0.00022057089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899006,0.00002866729,0.0004287301,0.00020192783,0.00020588862,0.00014475391],"domain_scores_gemma":[0.9990894,0.000012248984,0.00026841296,0.000354003,0.00021927085,0.000056623547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051948923,0.0001053673,0.00018809114,0.000032412612,0.000027152471,0.000012521986,0.00020384013,0.00012479338,0.000004743846],"category_scores_gemma":[0.0003187792,0.00010271284,0.00009295063,0.00012285748,0.00011551112,0.000009265983,0.0001044752,0.00006517116,0.0000014253467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051406187,0.00007798055,0.003844364,0.000026876996,0.000028354112,1.8807579e-7,0.00036495348,0.0004522241,0.99396884,0.00026456267,0.00048616435,0.0004340706],"study_design_scores_gemma":[0.00095062226,0.000045604058,0.0013604078,0.000017835018,0.000017242646,0.0000035259282,0.00019881153,0.0004601229,0.9877062,0.0000556711,0.009081598,0.000102371254],"about_ca_topic_score_codex":0.00006571112,"about_ca_topic_score_gemma":0.0000036055958,"teacher_disagreement_score":0.029131925,"about_ca_system_score_codex":0.000006116355,"about_ca_system_score_gemma":0.000060680926,"threshold_uncertainty_score":0.4188508},"labels":[],"label_agreement":null},{"id":"W2134812257","doi":"10.1039/c1md00260k","title":"Inhibitory effect of bortezomib on human multiple myeloma cells when combined with epigallocatechin-gallate (EGCG) analogs","year":2011,"lang":"en","type":"article","venue":"MedChemComm","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute; U.S. Food and Drug Administration; Hong Kong Polytechnic University","keywords":"Bortezomib; Gallate; Multiple myeloma; Epigallocatechin gallate; Chemistry; Inhibitory postsynaptic potential; Cancer research; Pharmacology; Biochemistry; Medicine; Internal medicine; Polyphenol; Nuclear chemistry; Antioxidant","score_opus":0.03562589046420497,"score_gpt":0.2846581664059509,"score_spread":0.2490322759417459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134812257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9837587,0.00007053526,0.000023821183,0.000094429364,0.000073115545,0.0012670129,0.000020585241,0.00013124855,0.014560557],"genre_scores_gemma":[0.9974356,0.0000120015775,0.0011375035,0.000086814085,0.000061365936,0.000107136104,0.00010701765,0.00007446121,0.0009780751],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99763066,0.00020352301,0.00042748684,0.0004825291,0.0006695602,0.00058622425],"domain_scores_gemma":[0.99809307,0.00025420194,0.0001825173,0.0008900733,0.0001335927,0.0004465261],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045698663,0.00041966647,0.00081981235,0.00028697104,0.00013826578,0.000012805668,0.00026110254,0.00016900926,0.00039462183],"category_scores_gemma":[0.00010391057,0.0002798435,0.00019116244,0.00021099581,0.00027628482,0.000080821614,0.00010118431,0.0004419796,0.00015790743],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016476734,0.0025871643,0.67134655,0.0008441545,0.001381793,0.001223684,0.0016187228,0.0000022334318,0.29357162,0.00015720272,0.0021913967,0.008598711],"study_design_scores_gemma":[0.013092853,0.010250579,0.16582966,0.0002780028,0.00017102303,0.000019060668,0.00003342946,0.00008776774,0.8096877,0.00007775189,0.00023796022,0.00023424244],"about_ca_topic_score_codex":0.0007510374,"about_ca_topic_score_gemma":0.00019793917,"teacher_disagreement_score":0.516116,"about_ca_system_score_codex":0.00012552136,"about_ca_system_score_gemma":0.00007783439,"threshold_uncertainty_score":0.99996537},"labels":[],"label_agreement":null},{"id":"W2135001209","doi":"10.1039/c3md00308f","title":"Fragment growing to retain or alter the selectivity of anchored kinase hinge-binding fragments","year":2013,"lang":"en","type":"article","venue":"MedChemComm","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK; Astex Pharmaceuticals","keywords":"Fragment (logic); Hinge; Selectivity; Chemistry; Kinase; Cell biology; Stereochemistry; Biology; Biochemistry; Computer science; Algorithm; Engineering; Structural engineering","score_opus":0.013281992237042534,"score_gpt":0.27283265329517126,"score_spread":0.25955066105812874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135001209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99443364,0.00008579512,0.0020341098,0.001679013,0.0001715483,0.0005971078,0.000009547089,0.000014577003,0.0009746496],"genre_scores_gemma":[0.9951315,0.0000106207135,0.0019225142,0.00077579555,0.00016661991,0.00029056068,0.000023501778,0.000025731915,0.0016531412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887216,0.00011342727,0.00023816497,0.00030122118,0.0001866723,0.00028836654],"domain_scores_gemma":[0.99911773,0.00004761872,0.00010025563,0.0005303009,0.000107976884,0.00009609386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029780227,0.00016010243,0.0001578504,0.00004828442,0.00013744952,0.00003792575,0.00031929906,0.00009555695,0.00028930118],"category_scores_gemma":[0.0003205917,0.000112350135,0.00008889648,0.0001552336,0.00004437668,0.000015759771,0.00024629908,0.00016963399,0.00006215575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047102105,0.0000804265,0.0017564679,0.000016272359,0.0000729156,0.0000014623147,0.00020187849,0.000025378213,0.98198014,0.000013805883,0.011809752,0.003994385],"study_design_scores_gemma":[0.00026335442,0.00018002416,0.001843416,0.00004326147,0.000015482983,0.0000069883145,0.0001941396,0.00006670038,0.98109585,0.000059638536,0.01608469,0.00014646904],"about_ca_topic_score_codex":0.00021345526,"about_ca_topic_score_gemma":0.000057093268,"teacher_disagreement_score":0.004274937,"about_ca_system_score_codex":0.000055509856,"about_ca_system_score_gemma":0.000040608702,"threshold_uncertainty_score":0.45815054},"labels":[],"label_agreement":null},{"id":"W2137076228","doi":"10.1039/c2md20173a","title":"Two-in-one: a pH-sensitive, acridine-based, fluorescent probe binds G-quadruplexes in oncogene promoters","year":2012,"lang":"en","type":"article","venue":"MedChemComm","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kensington Health","funders":"","keywords":"Cyanine; Acridine; Fluorescence; G-quadruplex; Chemistry; Acridine derivatives; Promoter; Combinatorial chemistry; Biophysics; Biochemistry; Stereochemistry; Biology; DNA; Organic chemistry; Gene; Gene expression","score_opus":0.017174604198647483,"score_gpt":0.2851727122096022,"score_spread":0.26799810801095475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137076228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966565,0.0004829349,0.0013367045,0.0006169306,0.000069536276,0.0003506725,0.000014851559,0.000067646855,0.00040424734],"genre_scores_gemma":[0.98189795,0.000094760624,0.017068913,0.0003973489,0.0002172809,0.000040138544,0.00017027919,0.00003561724,0.00007772282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982783,0.00013929559,0.00035129712,0.00043082846,0.00019518772,0.00060508336],"domain_scores_gemma":[0.99920094,0.000018766666,0.000110133966,0.00046667797,0.00006806051,0.0001354233],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005494685,0.00027783023,0.00031846602,0.00018250578,0.00004880228,0.000018356037,0.0001843343,0.00019059006,0.0000028351722],"category_scores_gemma":[0.000105238956,0.00025320073,0.00013343197,0.0003515029,0.00012399297,0.000010340534,0.00012504315,0.00021007913,0.0000060496636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012432848,0.0004965215,0.026337823,0.000026581545,0.00002631361,0.000010840034,0.00006314947,0.0000122105,0.9674836,0.00001708182,0.00021489337,0.005186651],"study_design_scores_gemma":[0.0008502268,0.00012257593,0.0033940503,0.00008477654,0.000022445362,0.000011598003,0.00007303348,0.00017458758,0.9925377,0.000018187002,0.0023720823,0.00033878555],"about_ca_topic_score_codex":0.000079082834,"about_ca_topic_score_gemma":0.00029390873,"teacher_disagreement_score":0.025054045,"about_ca_system_score_codex":0.00008890922,"about_ca_system_score_gemma":0.00005997082,"threshold_uncertainty_score":0.999992},"labels":[],"label_agreement":null},{"id":"W2139214929","doi":"10.1039/c2md00253a","title":"Understanding and overcoming aminoglycoside resistance caused by N-6′-acetyltransferase","year":2011,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Aminoglycoside; Acetyltransferase; Antibiotic resistance; Antibiotics; Biology; Microbiology; Genetics; Gene","score_opus":0.05531181673127936,"score_gpt":0.2419600300714103,"score_spread":0.18664821334013093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139214929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97485906,0.0008410646,0.014981214,0.00010611696,0.00010694142,0.00014267527,0.000027579727,0.000026663392,0.008908668],"genre_scores_gemma":[0.99606615,0.00031447434,0.0018224863,0.00021433124,0.00005257072,0.0000055922674,0.000043004075,0.000034710458,0.0014466585],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896663,0.00004944315,0.00020613127,0.00037061356,0.00011285461,0.0002943438],"domain_scores_gemma":[0.99942005,0.000019344952,0.00005778457,0.0003692759,0.000021872818,0.00011165811],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016687294,0.00018892853,0.00017294622,0.000025873553,0.00012004547,0.000029206742,0.00016979601,0.00014181573,0.00005445946],"category_scores_gemma":[0.00004911562,0.00019173621,0.000046997142,0.000061802035,0.00018533808,0.0000084120575,0.000063064515,0.00009858202,0.000004373703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015823155,0.000044849043,0.024978975,0.0000474849,0.000052633135,0.000011802107,0.00027721556,8.8303466e-8,0.9631012,0.0007828472,0.010470099,0.00007453758],"study_design_scores_gemma":[0.00089031056,0.00009133167,0.010203286,0.00006293976,0.000032159023,0.00001018695,0.00046686598,0.0000051443517,0.9689001,0.0005665604,0.018358832,0.00041231725],"about_ca_topic_score_codex":0.000019216033,"about_ca_topic_score_gemma":0.00014918121,"teacher_disagreement_score":0.021207094,"about_ca_system_score_codex":0.000040421484,"about_ca_system_score_gemma":0.000024291405,"threshold_uncertainty_score":0.7818776},"labels":[],"label_agreement":null},{"id":"W2139565345","doi":"10.1039/c4md00399c","title":"4-Thiazolidinone derivatives as potent antimicrobial agents: microwave-assisted synthesis, biological evaluation and docking studies","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Antimicrobial; Antifungal; Docking (animal); Combinatorial chemistry; Chemistry; Reverse transcriptase; Human immunodeficiency virus (HIV); Antibacterial activity; Stereochemistry; Microbiology; Biology; Biochemistry; Organic chemistry; Virology; Bacteria; Medicine; Veterinary medicine","score_opus":0.11451403635647228,"score_gpt":0.33224510102277444,"score_spread":0.21773106466630215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139565345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925868,0.00057616364,0.00006130789,0.0011160455,0.000081059006,0.000118523145,0.000008322423,0.000098290424,0.005353499],"genre_scores_gemma":[0.99807006,0.00047981154,0.000720309,0.00040223412,0.00019283811,0.000061506646,0.000018356171,0.000014404863,0.000040455387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982507,0.00030954267,0.0003294266,0.000526256,0.00024489683,0.00033916783],"domain_scores_gemma":[0.9981139,0.0011736011,0.00019546064,0.00028036477,0.00014183663,0.000094836745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010443253,0.00028873238,0.00050234114,0.00003907301,0.00028359806,0.00006007124,0.00021224516,0.00023473601,0.0004491998],"category_scores_gemma":[0.0037333982,0.00019162004,0.000114436974,0.000092343995,0.00029507265,0.00007811381,0.00026163014,0.00020226251,0.000032116877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058476042,0.00021877185,0.007842394,0.000061051025,0.00014796553,0.0000030484218,0.0001816995,0.0000010490198,0.82793814,0.000086203065,0.00027582335,0.1631854],"study_design_scores_gemma":[0.00041633638,0.000043119224,0.025635028,0.00016703499,0.00009202082,0.000036510384,0.0005252843,0.00021192188,0.96854377,0.00073073525,0.003272359,0.00032588028],"about_ca_topic_score_codex":0.00002380625,"about_ca_topic_score_gemma":0.000006267096,"teacher_disagreement_score":0.16285951,"about_ca_system_score_codex":0.00009642317,"about_ca_system_score_gemma":0.000017692286,"threshold_uncertainty_score":0.78140384},"labels":[],"label_agreement":null},{"id":"W2140033213","doi":"10.1039/c4md00007b","title":"Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography","year":2014,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Engineering and Physical Sciences Research Council","keywords":"Chemistry; Flow chemistry; Combinatorial chemistry; Chromatography; Organic chemistry; Catalysis","score_opus":0.012263814824235301,"score_gpt":0.27631664321749017,"score_spread":0.2640528283932549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140033213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940547,0.00073514885,0.004014577,0.00004686387,0.00006664648,0.00009484264,0.000030139294,0.0000051947795,0.00095189014],"genre_scores_gemma":[0.9696325,0.000021810327,0.030223893,0.000020384181,0.000028980938,0.0000050912195,0.000012966673,0.000014163319,0.000040230752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908984,0.00017153738,0.000316467,0.00018317444,0.00013294513,0.00010605515],"domain_scores_gemma":[0.99910337,0.000041991367,0.00028511343,0.00045383588,0.00006946727,0.000046227262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039455926,0.00012888915,0.0002714681,0.000024680112,0.0000421402,0.0000030196873,0.00019354776,0.0001490507,0.000022302074],"category_scores_gemma":[0.00034494643,0.000100673475,0.00015243384,0.00012801283,0.000287542,0.0000036543165,0.00013331846,0.00007473076,6.851719e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025619218,0.000066577035,0.0045376685,0.00012563144,0.0000570797,4.6347253e-8,0.00003215923,0.000010451143,0.98732466,0.000011614466,0.000079326586,0.0077291923],"study_design_scores_gemma":[0.00024849054,0.000024696492,0.006131599,0.000050871535,0.000047228586,0.000006628767,0.000034553763,0.001423386,0.9911866,0.00003248477,0.00071476307,0.00009869853],"about_ca_topic_score_codex":0.00010216361,"about_ca_topic_score_gemma":0.0000062121353,"teacher_disagreement_score":0.026209315,"about_ca_system_score_codex":0.000009121691,"about_ca_system_score_gemma":0.000032002252,"threshold_uncertainty_score":0.41053453},"labels":[],"label_agreement":null},{"id":"W2141242243","doi":"10.1039/c2md20189e","title":"The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains","year":2012,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Genome Canada; Eli Lilly Canada; Wellcome Trust; Novartis Foundation","keywords":"Bromodomain; Combinatorial chemistry; Computational biology; Chemistry; Stereochemistry; Biology; Biochemistry; Epigenetics; Gene","score_opus":0.008533852323883984,"score_gpt":0.22782892032022314,"score_spread":0.21929506799633916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141242243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962668,0.0022261234,0.00018998457,0.00037077133,0.000062946274,0.00021567059,0.0000052996315,0.000003470197,0.00065896305],"genre_scores_gemma":[0.99912655,0.00027978077,0.0003614442,0.00005059141,0.00006645035,0.00002274522,0.0000016102466,0.000010145189,0.000080692276],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932617,0.00014366828,0.00016417108,0.00010857461,0.00011163318,0.00014578721],"domain_scores_gemma":[0.99942374,0.00013166075,0.000120889395,0.00022575948,0.000046570734,0.000051351846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041774343,0.000095738586,0.00011017661,0.000016225573,0.00012350964,0.000008655714,0.00012842561,0.0000830458,0.0000023288135],"category_scores_gemma":[0.00040384283,0.000056566063,0.000044132925,0.000071332324,0.0002905307,0.0000059086374,0.00013454673,0.00006291681,4.729172e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082997314,0.00008706012,0.014451777,0.000028529163,0.000082759085,6.856454e-8,0.00033975372,0.0000029365617,0.9709912,0.0008572662,0.0022910135,0.01078463],"study_design_scores_gemma":[0.0001587372,0.000053525786,0.006524097,0.000019529416,0.000020901889,0.0000070729207,0.00017983171,0.000013878637,0.9888183,0.00016656221,0.0039691436,0.00006840488],"about_ca_topic_score_codex":0.00002153007,"about_ca_topic_score_gemma":0.000008249196,"teacher_disagreement_score":0.017827105,"about_ca_system_score_codex":0.0000057027046,"about_ca_system_score_gemma":0.000031546828,"threshold_uncertainty_score":0.2306697},"labels":[],"label_agreement":null},{"id":"W2143858450","doi":"10.1039/c5md00290g","title":"Sulfasalazine in ionic liquid form with improved solubility and exposure","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Ionic liquids properties and applications","field":"Chemical Engineering","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Ionic liquid; Solubility; Sulfasalazine; Chemistry; Ionic bonding; Organic chemistry; Ion; Medicine; Internal medicine","score_opus":0.018247293453044176,"score_gpt":0.2216578172800579,"score_spread":0.20341052382701372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143858450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99552804,0.00037049956,0.0009222608,0.0013474289,0.00003039056,0.00020268084,0.0000048405427,0.00009491933,0.0014989453],"genre_scores_gemma":[0.9982163,0.000011493966,0.0009626965,0.00008736655,0.000057700327,0.00010449098,0.000010889081,0.000020047195,0.00052905106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992485,0.000009640282,0.00019089037,0.00020364314,0.00010520989,0.00024209739],"domain_scores_gemma":[0.9994556,0.000029981447,0.000029244666,0.00029972717,0.000053685588,0.00013179256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022033224,0.00012262145,0.00016391864,0.000025680687,0.000031782314,0.000011480174,0.00012496694,0.0000743881,0.000027149976],"category_scores_gemma":[0.000057476325,0.00008989217,0.000019189143,0.000116848525,0.000054405176,0.000100459416,0.00009503521,0.00019172617,0.000012854339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032533486,0.0015547768,0.012840895,0.00075982255,0.0002142621,0.000033378194,0.013705512,0.0013085031,0.9247405,0.014280975,0.003993117,0.023314912],"study_design_scores_gemma":[0.008237677,0.0016884796,0.0020237742,0.000165565,0.0000539588,0.00006548845,0.0016216434,0.076598756,0.8793063,0.0012998435,0.02779684,0.0011416377],"about_ca_topic_score_codex":0.00014849025,"about_ca_topic_score_gemma":0.00012271309,"teacher_disagreement_score":0.075290255,"about_ca_system_score_codex":0.00010706328,"about_ca_system_score_gemma":0.00005199771,"threshold_uncertainty_score":0.36656964},"labels":[],"label_agreement":null},{"id":"W2146752206","doi":"10.1039/c3md00011g","title":"Identification of a potent salicylic acid-based inhibitor of tyrosine phosphatase PTP1B","year":2013,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Canadian Celiac Association; University of Toronto","funders":"","keywords":"Protein tyrosine phosphatase; Phosphatase; Identification (biology); Salicylic acid; Chemistry; Small molecule; Biochemistry; Papain; Tyrosine; Computational biology; Biology; Enzyme; Botany","score_opus":0.0073810945973051025,"score_gpt":0.23392165532654033,"score_spread":0.22654056072923523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146752206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97268367,0.020448636,0.004455924,0.0007269992,0.00019330389,0.00086916424,0.0004899085,0.000028511671,0.00010387097],"genre_scores_gemma":[0.99734735,0.00004838892,0.0014010728,0.00019094213,0.000075901145,0.0001246706,0.0007040142,0.000025770749,0.00008190167],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874026,0.00004994351,0.0005067945,0.0002825739,0.00021710811,0.0002033473],"domain_scores_gemma":[0.99858683,0.000015117647,0.00033716546,0.0007325672,0.0002414497,0.00008689315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021309785,0.00016892861,0.00022487764,0.00005733166,0.000032892138,0.00001446611,0.00030831833,0.00011796965,0.00006718847],"category_scores_gemma":[0.00028008723,0.0001609605,0.000112827736,0.00016403415,0.00016192898,0.000009761777,0.00011961629,0.00006284456,0.000029916571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058624548,0.00020138845,0.0008853004,0.0001003326,0.000027648071,6.0781764e-7,0.000012019522,0.000020371072,0.98788154,0.0003093517,0.0063856,0.0041172314],"study_design_scores_gemma":[0.0007140806,0.00017955712,0.0028835288,0.00003699784,0.000024634615,0.0000020104665,0.000017082957,0.00012233158,0.9940472,0.00010297023,0.0017173642,0.0001521874],"about_ca_topic_score_codex":0.00016357972,"about_ca_topic_score_gemma":0.000007432071,"teacher_disagreement_score":0.024663657,"about_ca_system_score_codex":0.000015401078,"about_ca_system_score_gemma":0.00007756101,"threshold_uncertainty_score":0.6563778},"labels":[],"label_agreement":null},{"id":"W2150373538","doi":"10.1039/c5md00400d","title":"Discovery of trace amine-associated receptor 1 ligands by molecular docking screening against a homology model","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Toronto Public Health; University of New Brunswick","funders":"National Supercomputer Centre, Linköpings Universitet; Vetenskapsrådet; Stiftelsen för Strategisk Forskning; Canadian Institutes of Health Research; Sven och Lilly Lawskis Fond för Naturvetenskaplig Forskning","keywords":"Docking (animal); Homology modeling; Computational biology; Amine gas treating; Chemistry; Homology (biology); Stereochemistry; Receptor; TRACE (psycholinguistics); Combinatorial chemistry; Biology; Biochemistry; Medicine; Amino acid; Organic chemistry; Philosophy; Enzyme","score_opus":0.017648548986714595,"score_gpt":0.2446794523600405,"score_spread":0.2270309033733259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150373538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92416626,0.0015607703,0.0731774,0.00012431525,0.00012119822,0.0001239876,0.000056680437,0.000021683642,0.0006477305],"genre_scores_gemma":[0.9951845,0.000084405394,0.003249903,0.00024462663,0.00006543805,0.000020166932,0.00042829165,0.00004895599,0.00067372574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857783,0.00007395378,0.00035901024,0.0003782354,0.0002523907,0.00035857278],"domain_scores_gemma":[0.9991459,0.000017834735,0.00021027483,0.00034478653,0.00014958203,0.0001316093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004798176,0.00023199587,0.00033295763,0.000052143198,0.00005600864,0.000030499,0.00030727652,0.0002877906,0.000007327753],"category_scores_gemma":[0.00023472263,0.00022966541,0.0001581748,0.000134736,0.00007106199,0.000013272677,0.00015948674,0.00016092225,0.000002352094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067027744,0.00010040998,0.00026859617,0.000010189315,0.00009177152,0.0000032536464,0.000153403,0.004033146,0.99060524,0.000055377273,0.0034308487,0.0011807241],"study_design_scores_gemma":[0.00092335127,0.00021988119,0.0000053095064,0.000038900933,0.000025040463,0.000003387134,0.00021600825,0.0086975545,0.9877886,0.00012889392,0.0016852653,0.00026777986],"about_ca_topic_score_codex":0.000028080482,"about_ca_topic_score_gemma":0.000006909204,"teacher_disagreement_score":0.071018256,"about_ca_system_score_codex":0.000030115167,"about_ca_system_score_gemma":0.00008900295,"threshold_uncertainty_score":0.93654835},"labels":[],"label_agreement":null},{"id":"W2151891718","doi":"10.1039/c5md00274e","title":"Tricyclic phenothiazine and phenoselenazine derivatives as potential multi-targeting agents to treat Alzheimer's disease","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Tricyclic; Phenothiazine; Disease; Oxidative stress; Neuroscience; Chemistry; Pharmacology; Psychology; Medicine; Internal medicine; Biochemistry","score_opus":0.08426761495109744,"score_gpt":0.35257127750575035,"score_spread":0.2683036625546529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151891718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98992753,0.005226818,0.00031456669,0.003186175,0.0001440251,0.00062398706,0.0000464929,0.000119556,0.0004108509],"genre_scores_gemma":[0.99250907,0.00010886139,0.0014193152,0.004255372,0.0005400822,0.000069051726,0.00020580928,0.000058610123,0.00083384034],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998302,0.00010935397,0.00032504206,0.00051998155,0.00037363285,0.0003700313],"domain_scores_gemma":[0.9978651,0.00005674231,0.00007690223,0.0003389543,0.00019736336,0.0014649403],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013216696,0.00033032292,0.0004151331,0.00015135316,0.00012248078,0.000048885453,0.000111501795,0.000051727562,0.00011009954],"category_scores_gemma":[0.00077953964,0.00027359548,0.000102845945,0.00028319302,0.00007993238,0.00015298794,0.00014522293,0.0001447624,0.0001363644],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013973721,0.009679656,0.29996663,0.0006233204,0.001186295,0.0051180725,0.01456236,0.00042128505,0.46913525,0.00015511982,0.11118397,0.073994294],"study_design_scores_gemma":[0.037764434,0.0019283498,0.51757026,0.0004843793,0.003730363,0.00021704817,0.0022939467,0.0060397536,0.38841316,0.0002435634,0.039045952,0.0022687602],"about_ca_topic_score_codex":0.00003889313,"about_ca_topic_score_gemma":0.00000296301,"teacher_disagreement_score":0.21760364,"about_ca_system_score_codex":0.000039763374,"about_ca_system_score_gemma":0.000119999786,"threshold_uncertainty_score":0.9999716},"labels":[],"label_agreement":null},{"id":"W2168535498","doi":"10.1039/c2md20342a","title":"Exploring the structural determinants of selective phosphopeptide recognition using bivalent metal-coordination complexes","year":2012,"lang":"en","type":"article","venue":"MedChemComm","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Celiac Association; University of Toronto","funders":"","keywords":"Bivalent (engine); Phosphopeptide; Cationic polymerization; Chemistry; Residue (chemistry); Metal; Stereochemistry; Combinatorial chemistry; Phosphorylation; Biochemistry; Polymer chemistry; Organic chemistry","score_opus":0.12462517402900493,"score_gpt":0.28967929593545416,"score_spread":0.16505412190644925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168535498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987495,0.00014753558,0.0001283369,0.000016858276,0.00022953584,0.0000837732,0.000010285329,0.000034887144,0.00059926906],"genre_scores_gemma":[0.9990363,0.000016459657,0.0006573886,0.000014918904,0.00015832894,0.000021857762,0.0000129615255,0.000021653375,0.00006013201],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990782,0.00005264721,0.0002649457,0.00014107765,0.00022511231,0.00023800522],"domain_scores_gemma":[0.9993784,0.000061584404,0.00019862161,0.00020569224,0.0001041183,0.000051601924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020151431,0.00014083344,0.0001808073,0.000048537437,0.00016862022,0.000016653543,0.00010687925,0.000045246125,0.00020766162],"category_scores_gemma":[0.0000943128,0.000107214364,0.000102820275,0.0001654414,0.0000533582,0.00033093855,0.00005105174,0.00015142826,0.000007658619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039204868,0.000037640635,0.008635611,0.00006996694,0.00004802884,8.2375647e-7,0.00097578706,0.000020683932,0.9268473,0.000009171284,0.000021673199,0.06329416],"study_design_scores_gemma":[0.00021615476,0.000014048754,0.007580826,0.00005042956,0.00006646536,0.00003666275,0.00045619684,0.0026915988,0.9884113,0.00007383614,0.00026521893,0.00013728323],"about_ca_topic_score_codex":0.00022941061,"about_ca_topic_score_gemma":0.00001745629,"teacher_disagreement_score":0.06315687,"about_ca_system_score_codex":0.00009125247,"about_ca_system_score_gemma":0.000009808817,"threshold_uncertainty_score":0.4372075},"labels":[],"label_agreement":null},{"id":"W2174136188","doi":"10.1039/c5md00429b","title":"Structural hybridization of three aminoglycoside antibiotics yields a potent broad-spectrum bactericide that eludes bacterial resistance enzymes","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Achaogen","keywords":"Antibiotics; Aminoglycoside; Broad spectrum; Enzyme; Microbiology; Antibiotic resistance; Chemistry; Biology; Computational biology; Combinatorial chemistry; Biochemistry","score_opus":0.03590738777425981,"score_gpt":0.2372481251879628,"score_spread":0.20134073741370298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2174136188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915371,0.00031130674,0.003643589,0.00035916385,0.0021346854,0.00022153601,0.000057035413,0.00012162295,0.0016139434],"genre_scores_gemma":[0.99506587,0.000017970639,0.004007175,0.00009529795,0.0004222859,0.0000020278944,0.000076461496,0.000032014927,0.00028091218],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981025,0.0000997058,0.0004563129,0.00040281433,0.000535941,0.00040275638],"domain_scores_gemma":[0.9987172,0.00007343952,0.0003484572,0.00055467465,0.00014933532,0.00015692474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036162074,0.00027934855,0.0004133465,0.00009792936,0.00011703674,0.00010913921,0.00037428743,0.00015318737,0.00032377607],"category_scores_gemma":[0.00017595457,0.00023542368,0.00009129861,0.00021506975,0.0001766591,0.0003968042,0.00013611637,0.00015323663,0.000029424162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005201713,0.000036175028,0.016064048,0.00009768565,0.000024652816,0.00001475533,0.0005764459,0.000101175494,0.97569436,0.0017527763,0.004646845,0.00047093825],"study_design_scores_gemma":[0.00065047806,0.00012442766,0.037539855,0.000066296154,0.000043188622,0.000024348441,0.00010887738,0.00010419603,0.9569608,0.0025011061,0.001606992,0.00026945188],"about_ca_topic_score_codex":0.00023855965,"about_ca_topic_score_gemma":0.0011406417,"teacher_disagreement_score":0.021475805,"about_ca_system_score_codex":0.000109836765,"about_ca_system_score_gemma":0.00010242472,"threshold_uncertainty_score":0.9600299},"labels":[],"label_agreement":null},{"id":"W2193668187","doi":"10.1039/c5md00459d","title":"Rubrolide analogues and their derived lactams as potential anticancer agents","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Organic Chemistry Synthesis Methods","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Cytotoxicity; Cytotoxic T cell; Apoptosis; Programmed cell death; Stereochemistry; Chemistry; Cancer cell; Cancer cell lines; Combinatorial chemistry; Cancer research; Computational biology; Biology; Cancer; Biochemistry; Genetics; In vitro","score_opus":0.038011133779207354,"score_gpt":0.2896719069318086,"score_spread":0.25166077315260127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2193668187","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9688537,0.0006042076,0.00031638343,0.00069598807,0.00014055036,0.00004698649,0.000022952103,0.00016376932,0.029155448],"genre_scores_gemma":[0.9953974,0.00008492577,0.0019997372,0.00023898215,0.00038385304,0.0000122919055,0.000031748714,0.000053957625,0.0017971216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856263,0.000059218644,0.0002773711,0.0004233585,0.0002822483,0.00039515045],"domain_scores_gemma":[0.9986782,0.00015471611,0.00012059565,0.0005855896,0.00007628737,0.00038459463],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037163316,0.00029658253,0.00037319495,0.000028630824,0.000080867314,0.00007033945,0.0003631418,0.0002012546,0.0016136789],"category_scores_gemma":[0.0006243029,0.00025752748,0.0000885424,0.00010276834,0.0001760757,0.00010482873,0.00024612626,0.00025424705,0.000077271085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056392968,0.000080923885,0.0032062724,0.000071303235,0.00010750628,0.00003462969,0.0007414024,0.0000014665093,0.97713643,0.0000087620365,0.0021002998,0.016454577],"study_design_scores_gemma":[0.0007171028,0.000010666394,0.0005678868,0.00003937973,0.000045831413,0.00009283051,0.0010804113,0.00023933037,0.9797596,0.0007720831,0.016379641,0.0002952401],"about_ca_topic_score_codex":0.00008571794,"about_ca_topic_score_gemma":0.000007591309,"teacher_disagreement_score":0.027358325,"about_ca_system_score_codex":0.00010938773,"about_ca_system_score_gemma":0.000102993974,"threshold_uncertainty_score":0.9999877},"labels":[],"label_agreement":null},{"id":"W2194867802","doi":"10.1039/c5md00384a","title":"Drug-target networks in aminoglycoside resistance: hierarchy of priority in structural drug design","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research","keywords":"Aminoglycoside; Drug; Antibiotics; Drug resistance; Hierarchy; Computational biology; Computer science; Intensive care medicine; Medicine; Pharmacology; Biology; Microbiology; Political science; Law","score_opus":0.03212692958877716,"score_gpt":0.30132753054360206,"score_spread":0.2692006009548249,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2194867802","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4694558,0.0011082683,0.52620614,0.0010727748,0.00053498277,0.00038725758,0.0000031447016,0.000066351975,0.0011652684],"genre_scores_gemma":[0.70049477,0.00000534972,0.299201,0.00009155768,0.00004618729,0.000016771328,0.000004593171,0.000010190414,0.00012958367],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9968733,0.0010658934,0.00059289334,0.00046693094,0.00056973705,0.0004311977],"domain_scores_gemma":[0.99791235,0.0010111561,0.00017776736,0.0006196571,0.00012532751,0.00015376639],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028388829,0.00021165887,0.00040764682,0.00028845272,0.000035387093,0.000061868646,0.0011992829,0.000067606605,0.0000052613077],"category_scores_gemma":[0.00036707343,0.00021215188,0.00006436941,0.0011753724,0.00010574461,0.00058314484,0.00044870493,0.0004031083,0.0000036030956],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028524894,0.00022614277,0.06120324,0.0000941639,0.000025563977,0.00015319414,0.01482961,0.866346,0.00018309528,0.036495946,0.005168638,0.014989172],"study_design_scores_gemma":[0.001413606,0.000024531404,0.07314328,0.00010695754,0.00000326001,0.000006698812,0.00013344492,0.78553706,0.0066966806,0.13201174,0.00056054036,0.00036218384],"about_ca_topic_score_codex":0.00021996703,"about_ca_topic_score_gemma":0.0004860113,"teacher_disagreement_score":0.23103893,"about_ca_system_score_codex":0.00029563103,"about_ca_system_score_gemma":0.00036034937,"threshold_uncertainty_score":0.86513025},"labels":[],"label_agreement":null},{"id":"W2208279242","doi":"10.1039/c5md90063h","title":"Antibiotic Resistance themed issue","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antibiotic Use and Resistance","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Antibiotic resistance; Antibiotics; Resistance (ecology); Biology; Medicine; Microbiology; Ecology","score_opus":0.02173808905274319,"score_gpt":0.24832545463551592,"score_spread":0.22658736558277273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2208279242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.547938,0.041823313,0.00065117463,0.007854316,0.0041425806,0.0005232079,0.000033500666,0.00057552947,0.39645836],"genre_scores_gemma":[0.8889479,0.00007192147,0.00038180768,0.00045172268,0.00008105337,0.0000014162428,0.000032165357,0.000018956645,0.11001306],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989952,0.0001062062,0.00021479404,0.00026412072,0.000054761567,0.00036492985],"domain_scores_gemma":[0.9992752,0.00006444072,0.00007940278,0.00045162797,0.00007700923,0.00005228876],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028552205,0.0001625705,0.00025920142,0.000048745213,0.0001134297,0.000013347185,0.00029970496,0.00019560505,0.00041656173],"category_scores_gemma":[0.0001025228,0.0001283674,0.00006382824,0.00015843948,0.00023997834,0.00006263544,0.00007500832,0.00022297651,0.0040962882],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003441446,0.00036168974,0.0074970433,0.000107960266,0.00023830062,0.00006054291,0.0019746008,0.0000016157062,0.16141509,0.005494387,0.8189702,0.003534411],"study_design_scores_gemma":[0.0010309556,0.00004347537,0.0014167187,0.000071927265,0.00002676503,0.00001822971,0.0006160242,8.4042415e-7,0.290818,0.00039978087,0.70535415,0.00020312428],"about_ca_topic_score_codex":0.00004051835,"about_ca_topic_score_gemma":0.000078191886,"teacher_disagreement_score":0.34100989,"about_ca_system_score_codex":0.000037955877,"about_ca_system_score_gemma":0.00006867931,"threshold_uncertainty_score":0.9966791},"labels":[],"label_agreement":null},{"id":"W2242492880","doi":"10.1039/c5md00388a","title":"Development of subnanomolar radiofluorinated (2-pyrrolidin-1-yl)imidazo[1,2-<i>b</i>]pyridazine pan-Trk inhibitors as candidate PET imaging probes","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Montreal Neurological Institute and Hospital; McGill University; Douglas Mental Health University Institute; Alberta Hospital Edmonton; University of Alberta","funders":"","keywords":"Pyridazine; Trk receptor; Chemistry; Stereochemistry; Biochemistry; Receptor","score_opus":0.030667345791905058,"score_gpt":0.27374591137836823,"score_spread":0.24307856558646318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2242492880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947706,0.0003039164,0.00011267159,0.00075035694,0.0008044714,0.00039528377,0.000013907337,0.00016154049,0.0026872372],"genre_scores_gemma":[0.9969387,0.000028224278,0.0017203575,0.00029792363,0.00018462854,0.000055521126,0.000037334717,0.000047256857,0.00069003645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99735755,0.00021653745,0.00070017314,0.00056480034,0.00065232813,0.00050862716],"domain_scores_gemma":[0.99871266,0.00007889225,0.00030088297,0.0004655589,0.00016761893,0.0002743697],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075875956,0.00033316392,0.00038520707,0.00020869859,0.00026380716,0.00008151641,0.0004636577,0.00006839154,0.000057026515],"category_scores_gemma":[0.00044199725,0.00028624997,0.00008913725,0.0005647043,0.00019122043,0.0004139515,0.00020759333,0.00026375585,0.00014218726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009086908,0.00019930452,0.0013487014,0.00005240199,0.000011473809,0.000106338564,0.0014439684,0.00005802208,0.9873881,0.00057784095,0.0020279544,0.006695031],"study_design_scores_gemma":[0.0008909593,0.00006124443,0.00017894259,0.00006705097,0.000018284296,0.00015011952,0.00014500422,0.00051840034,0.9607575,0.00022964954,0.036640152,0.00034269225],"about_ca_topic_score_codex":0.000077944074,"about_ca_topic_score_gemma":0.0000365536,"teacher_disagreement_score":0.034612197,"about_ca_system_score_codex":0.00016851688,"about_ca_system_score_gemma":0.00042425154,"threshold_uncertainty_score":0.999959},"labels":[],"label_agreement":null},{"id":"W2255845282","doi":"10.1039/c5md00552c","title":"Continuous flow photochemistry as an enabling synthetic technology: synthesis of substituted-6(5H)-phenanthridinones for use as poly(ADP-ribose) polymerase inhibitors","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"University of Manitoba","keywords":"Continuous flow; Intramolecular force; Polymerase; Chemistry; Poly ADP ribose polymerase; Combinatorial chemistry; Ribose; Photochemistry; Stereochemistry; Enzyme; Biochemistry; Biochemical engineering","score_opus":0.020188722937391334,"score_gpt":0.2960961910592878,"score_spread":0.2759074681218965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2255845282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885138,0.0015225232,0.0012128887,0.005978124,0.00045884794,0.0011235838,0.00027189613,0.0004279665,0.000490355],"genre_scores_gemma":[0.9933799,0.00027544898,0.0039413003,0.00034104873,0.00053695246,0.0007829925,0.000032684577,0.000121262594,0.000588447],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972023,0.00006635922,0.00078782724,0.00075475784,0.00048650126,0.0007022955],"domain_scores_gemma":[0.99668896,0.0008895204,0.0003995152,0.0012839987,0.00038014364,0.00035787403],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043912293,0.00048045893,0.0009347349,0.00040339862,0.00018394315,0.000034540408,0.00037567888,0.00049193273,0.0005653573],"category_scores_gemma":[0.0019160333,0.0003616863,0.00030754757,0.00046547284,0.00078715937,0.0003059158,0.00007950345,0.0002503945,0.000055189303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011466137,0.00050755666,0.0022333742,0.00019361972,0.00020676717,0.00006311429,0.00016390087,4.5687779e-7,0.9483576,0.0002523509,0.000709144,0.04616555],"study_design_scores_gemma":[0.0033813906,0.00032683555,0.000046531422,0.0018590012,0.00023050618,0.00031625392,0.0004660526,0.000041148127,0.98365206,0.0006395736,0.008597097,0.00044356467],"about_ca_topic_score_codex":0.00016491814,"about_ca_topic_score_gemma":0.000009176228,"teacher_disagreement_score":0.04572198,"about_ca_system_score_codex":0.00022645095,"about_ca_system_score_gemma":0.00038730432,"threshold_uncertainty_score":0.99988353},"labels":[],"label_agreement":null},{"id":"W2267004994","doi":"10.1039/c5md00590f","title":"Aryl and heteroaryl <i>N</i>-[4-[4-(2,3-substituted-phenyl)piperazine-1-yl]alkyl]carbamates with improved physico-chemical properties as dual modulators of dopamine D3 receptor and fatty acid amide hydrolase","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; Institute of Cancer Research","funders":"","keywords":"Piperazine; Aryl; Chemistry; Alkyl; Medicinal chemistry; Dopamine; Fatty acid; Combinatorial chemistry; Stereochemistry; Organic chemistry; Internal medicine; Medicine","score_opus":0.009048834536528131,"score_gpt":0.22792104048575135,"score_spread":0.21887220594922321,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2267004994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99220186,0.001913386,0.000070567105,0.004712945,0.00007306662,0.0007249981,0.000044996224,0.00010719812,0.00015095375],"genre_scores_gemma":[0.99712056,0.00029290555,0.00037437957,0.00020438485,0.00022135486,0.00014621849,0.00002988414,0.000080565456,0.0015297673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975777,0.000044368415,0.0004944508,0.0006738212,0.0005986909,0.00061095314],"domain_scores_gemma":[0.9983969,0.000037811013,0.0001593622,0.00061417866,0.0002758919,0.00051589945],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002549397,0.00045497942,0.00080457877,0.00014876346,0.00010800219,0.000050499795,0.00015669683,0.0001803472,0.00008696065],"category_scores_gemma":[0.000198827,0.00026220828,0.00011228083,0.00024451138,0.0012965236,0.00027072994,0.0002452028,0.00032871868,0.000012619283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015237536,0.0002815806,0.00760341,0.00041928372,0.00016550103,0.000033788005,0.00033174767,4.3347282e-7,0.97442865,0.000028418475,0.001303422,0.013879985],"study_design_scores_gemma":[0.0045055705,0.00076895003,0.0024527342,0.00046224412,0.00010988967,0.00029116715,0.00017801845,0.00032228066,0.9875092,0.00003383821,0.0029842046,0.0003819176],"about_ca_topic_score_codex":0.00019588658,"about_ca_topic_score_gemma":0.000018241191,"teacher_disagreement_score":0.013498067,"about_ca_system_score_codex":0.00009724266,"about_ca_system_score_gemma":0.00016996171,"threshold_uncertainty_score":0.999983},"labels":[],"label_agreement":null},{"id":"W2274639989","doi":"10.1039/c5md00568j","title":"Efficacy of a novel ferrocenyl diaryl butene citrate compound as a biocide for preventing healthcare-associated infections","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Disinfectant; Antiseptic; Biocide; Hand sanitizer; Medicine; Chemistry; Food science; Organic chemistry","score_opus":0.03487490881773639,"score_gpt":0.3024775023932495,"score_spread":0.2676025935755131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2274639989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892446,0.000043710246,0.0055444543,0.0031294837,0.00005067401,0.00027598458,0.00032857238,0.000114128794,0.0012684013],"genre_scores_gemma":[0.9964364,0.000031149397,0.0008465231,0.00015003883,0.000087872424,0.00011291572,0.000106303196,0.000033445867,0.0021953518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988878,0.000011417764,0.00039827527,0.00026977787,0.00011353863,0.0003192424],"domain_scores_gemma":[0.99882203,0.00034275788,0.00028624135,0.0002916439,0.00015315939,0.00010418727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016475527,0.00016178485,0.00026453062,0.00003989972,0.00022528032,0.000018669492,0.00021167676,0.00012643547,0.00017050932],"category_scores_gemma":[0.00024013648,0.00012870299,0.00017906926,0.00017163287,0.00008450089,0.00006098718,0.00007566335,0.00010114878,0.000015802416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028654602,0.0009990808,0.0031652986,0.000106837186,0.00011547316,4.1799697e-7,0.000110374596,0.0000024601766,0.99073714,0.0010723409,0.0011093701,0.002552553],"study_design_scores_gemma":[0.0047457335,0.00006334249,0.0036339646,0.00055062113,0.00011921,0.000013007229,0.00006853873,0.00018754392,0.97472316,0.0010031689,0.01450543,0.00038629957],"about_ca_topic_score_codex":0.00037516557,"about_ca_topic_score_gemma":0.00010976214,"teacher_disagreement_score":0.016013999,"about_ca_system_score_codex":0.000092088914,"about_ca_system_score_gemma":0.000089073605,"threshold_uncertainty_score":0.5248355},"labels":[],"label_agreement":null},{"id":"W2288528862","doi":"10.1039/c6md90014c","title":"Correction: Effect of dibucaine hydrochloride on raft-like lipid domains in model membrane systems","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hatch (Canada)","funders":"","keywords":"Raft; Dibucaine; Hydrochloride; Chemistry; Biophysics; Biology; Biochemistry; Polymer; Organic chemistry","score_opus":0.006075720118444937,"score_gpt":0.23630747702772972,"score_spread":0.2302317569092848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2288528862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99529505,0.00007783421,0.00041127455,0.00011864561,0.001741127,0.00030732664,0.000026758315,0.000020855121,0.0020011314],"genre_scores_gemma":[0.9955753,0.00008486401,0.000027487366,0.0000810455,0.0004926501,0.00006385284,0.000045693596,0.000031696356,0.0035973731],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987126,0.00010125117,0.000320968,0.00037258456,0.00020773376,0.0002848431],"domain_scores_gemma":[0.99912524,0.000085956664,0.00011093471,0.0005443174,0.00004213096,0.00009143529],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032374822,0.00024339002,0.0003646162,0.000084619714,0.000036807287,0.0000082763245,0.00022770457,0.00021028174,0.000019307274],"category_scores_gemma":[0.00011323719,0.00015381715,0.00012885054,0.00011729938,0.00007985366,0.000005849119,0.00007284394,0.000116188734,0.000014318983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005004606,0.00005889249,0.0018915255,0.00006903906,0.000025198255,0.0000043610503,0.000026906813,0.0005204742,0.99338806,0.000016218006,0.00183706,0.001661815],"study_design_scores_gemma":[0.0020542315,0.0005545337,0.00030317498,0.00013022889,0.00003355109,0.000024284143,0.000009128529,0.0003950196,0.99003094,0.0000028501752,0.0062569235,0.00020515449],"about_ca_topic_score_codex":0.000036430352,"about_ca_topic_score_gemma":0.000038937396,"teacher_disagreement_score":0.004419863,"about_ca_system_score_codex":0.000037763886,"about_ca_system_score_gemma":0.000045637178,"threshold_uncertainty_score":0.62724817},"labels":[],"label_agreement":null},{"id":"W2316275696","doi":"10.1039/c6md00109b","title":"Host–guest strategy to potently camouflage and restore the activity and toxicity of drugs affecting bacterial growth and viability","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Camouflage; Toxicity; Salt (chemistry); Drug; Host (biology); Chemistry; Drug delivery; Biology; Pharmacology; Ecology; Organic chemistry","score_opus":0.008991822207340351,"score_gpt":0.21882372847604367,"score_spread":0.20983190626870332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2316275696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99781674,0.00014278214,0.00003182941,0.0011255522,0.00023379138,0.00024337566,0.00006797515,0.000022521088,0.00031542682],"genre_scores_gemma":[0.9995699,0.000062572675,0.000028251323,0.000060096867,0.00006216902,0.0000053334575,0.0000027844121,0.000010173224,0.00019873244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991053,0.00021480836,0.00014645861,0.00027316995,0.000027045888,0.00023323529],"domain_scores_gemma":[0.9991725,0.00047782288,0.000093387804,0.00019076867,0.00002993809,0.000035579247],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036401104,0.00016072187,0.00028059797,0.000032216638,0.00021536587,0.00002386375,0.00009599245,0.00013748342,0.00003721791],"category_scores_gemma":[0.00016325858,0.00009400403,0.000033440934,0.000045172546,0.0006158632,0.00014713341,0.00023153136,0.00014703127,0.0000033065573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019841766,0.000041553852,0.0068687717,0.000046939367,0.000032943903,7.0973573e-7,0.0007601204,1.3368791e-8,0.9851961,0.00009814356,0.00025323807,0.0065030614],"study_design_scores_gemma":[0.00048991706,0.00021032624,0.06831269,0.00005057155,0.000023216282,0.000022150454,0.00040214925,1.954386e-7,0.92997485,0.00007613598,0.00030623746,0.00013158153],"about_ca_topic_score_codex":0.0005618165,"about_ca_topic_score_gemma":0.00015599017,"teacher_disagreement_score":0.061443917,"about_ca_system_score_codex":0.000015385303,"about_ca_system_score_gemma":0.000019658526,"threshold_uncertainty_score":0.38333732},"labels":[],"label_agreement":null},{"id":"W2364148038","doi":"10.1039/c6md00065g","title":"Open PHACTS computational protocols for <i>in silico</i> target validation of cellular phenotypic screens: knowing the knowns","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cell Image Analysis Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"De Beers (Canada)","funders":"Instituto de Salud Carlos III; Horizon 2020 Framework Programme; Innovative Medicines Initiative; European Federation of Pharmaceutical Industries and Associations","keywords":"In silico; Phenotype; Computer science; Computational biology; Biology; Genetics","score_opus":0.02336625622666653,"score_gpt":0.31905983315099223,"score_spread":0.2956935769243257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2364148038","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3376399,0.00045297507,0.6221207,0.0028834485,0.000038314207,0.028785897,0.000074609445,0.000056840418,0.007947343],"genre_scores_gemma":[0.9814479,0.000007677728,0.013667954,0.0001925763,0.00008715363,0.003756652,0.0001942705,0.000024400364,0.0006214358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990348,0.000096551215,0.00030271476,0.0002707619,0.00012532943,0.00016979488],"domain_scores_gemma":[0.9991696,0.00008611602,0.00014999852,0.00041395164,0.00014988957,0.000030446778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006893523,0.00011918828,0.00018410041,0.00004130379,0.0000554333,0.000030799074,0.0005695529,0.00007746534,0.000034251058],"category_scores_gemma":[0.0001996166,0.00007737991,0.00009876692,0.00010880052,0.000074283176,0.000014631999,0.00025622742,0.00004210276,0.0000035741257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007140444,0.00011012237,0.0011013285,0.00002288501,0.000035533172,3.4607228e-7,0.000031194333,0.00006524337,0.9892338,0.0001559968,0.0043182126,0.0048539224],"study_design_scores_gemma":[0.00076054287,0.00009835845,0.0001670501,0.00005381673,0.000014470529,6.7848833e-7,0.000017696118,0.00018411073,0.9468776,0.0015674011,0.050148435,0.00010981748],"about_ca_topic_score_codex":0.00002466448,"about_ca_topic_score_gemma":0.000018417313,"teacher_disagreement_score":0.643808,"about_ca_system_score_codex":0.00001933034,"about_ca_system_score_gemma":0.00006792224,"threshold_uncertainty_score":0.31554613},"labels":[],"label_agreement":null},{"id":"W2414912583","doi":"10.1039/c6md00079g","title":"Structural modifications of the neomycin class of aminoglycosides","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"","keywords":"Neomycin; Aminoglycoside; Antibiotics; Pharmacology; Biology; Microbiology","score_opus":0.01653627655460358,"score_gpt":0.23549901968305037,"score_spread":0.2189627431284468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414912583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99664754,0.00020065861,0.0011572595,0.0006726007,0.000083622625,0.000112036345,0.000025714815,0.0000033585989,0.0010972188],"genre_scores_gemma":[0.99841934,0.000026858443,0.00064527337,0.000038418886,0.000042004925,0.000012744714,0.0000026432026,0.000008163301,0.00080453797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99947155,0.000056097797,0.0001659984,0.000116430165,0.00009581215,0.000094101706],"domain_scores_gemma":[0.9993006,0.000026148049,0.00011726806,0.00047529826,0.000057165416,0.000023517197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009614486,0.00007030089,0.00009697273,0.00001329936,0.000033220727,0.0000020892762,0.00028507833,0.00007075794,0.000040230985],"category_scores_gemma":[0.000116576164,0.000036769954,0.000085362466,0.000046060024,0.00011471505,0.0000017943751,0.00007812038,0.000021333484,0.000002203601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014260029,0.000008652173,0.0013278618,0.000008439968,0.000016385658,4.4324395e-8,0.000021419655,0.0000019113352,0.989186,0.0012652556,0.0002674562,0.007882349],"study_design_scores_gemma":[0.0001584058,0.00003723149,0.0043582222,0.000021530303,0.000009353613,0.0000024489823,0.000021191328,0.0000047622298,0.9912874,0.0010213638,0.0030236412,0.00005443522],"about_ca_topic_score_codex":0.000012314669,"about_ca_topic_score_gemma":0.000010175186,"teacher_disagreement_score":0.007827913,"about_ca_system_score_codex":0.0000045741785,"about_ca_system_score_gemma":0.000028654424,"threshold_uncertainty_score":0.14994352},"labels":[],"label_agreement":null},{"id":"W2426482612","doi":"10.1039/c6md00228e","title":"Design, synthesis, biological evaluation and docking studies of sulfonyl isatin derivatives as monoamine oxidase and caspase-3 inhibitors","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bell (Canada)","funders":"National Research Foundation","keywords":"Isatin; Monoamine oxidase; Sulfonyl; Chemistry; Docking (animal); Combinatorial chemistry; Monoamine neurotransmitter; Pharmacology; Stereochemistry; Biochemistry; Enzyme; Organic chemistry; Biology; Medicine; Serotonin; Receptor","score_opus":0.11387054248740913,"score_gpt":0.3535852096845828,"score_spread":0.23971466719717366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2426482612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99204516,0.006219571,0.00035330246,0.0007694713,0.000033891938,0.0004648406,0.000010027617,0.0000274044,0.00007634464],"genre_scores_gemma":[0.99660766,0.0011237307,0.0019961777,0.00006339857,0.000035767316,0.000120751705,0.000004258771,0.000012189802,0.000036045716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989276,0.00018235395,0.00022889487,0.00027961135,0.000217609,0.00016393696],"domain_scores_gemma":[0.99874365,0.0007239703,0.00011664361,0.00016315107,0.00012993466,0.0001226722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051493384,0.00017475591,0.00036864588,0.000083828396,0.00007802824,0.000006744748,0.000032426768,0.000066804096,0.00005463887],"category_scores_gemma":[0.0015908051,0.000097978715,0.00003612144,0.00008014401,0.00019138148,0.00006933533,0.00006939982,0.000040190625,0.000004178712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005750334,0.00050728803,0.09231682,0.00015349044,0.00072811317,0.00008532446,0.0014785777,8.583607e-7,0.7084157,0.00028365222,0.00016790959,0.19528724],"study_design_scores_gemma":[0.0026811096,0.0005673681,0.0792024,0.00056431716,0.00038322675,0.000038543305,0.0008551299,0.0000987832,0.9132071,0.0020050807,0.0002332839,0.00016363959],"about_ca_topic_score_codex":0.000019166962,"about_ca_topic_score_gemma":0.0000028025627,"teacher_disagreement_score":0.20479143,"about_ca_system_score_codex":0.00006338871,"about_ca_system_score_gemma":0.000042630974,"threshold_uncertainty_score":0.3995456},"labels":[],"label_agreement":null},{"id":"W2429737392","doi":"10.1039/c6md00159a","title":"Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK","keywords":"HSF1; Heat shock factor; Chemistry; Heat shock protein; Biology; Hsp70; Biochemistry; Gene","score_opus":0.013451521761885082,"score_gpt":0.25750572622571183,"score_spread":0.24405420446382675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2429737392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975371,0.00077425985,0.00015634563,0.0006115517,0.0001026021,0.00031155805,0.00018275305,0.000006045192,0.00031783688],"genre_scores_gemma":[0.998683,0.0001842121,0.000050461513,0.00002843848,0.00009556859,0.00002301985,0.000014408733,0.000020376205,0.0009005243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876,0.000103808256,0.0002827931,0.000279488,0.00030178527,0.00027214785],"domain_scores_gemma":[0.99910676,0.000042079042,0.00006486047,0.0005894224,0.0001106062,0.00008625647],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014978567,0.00016184339,0.00021271821,0.000041598047,0.000056540583,0.000012569539,0.00031980235,0.00015010318,0.000020376901],"category_scores_gemma":[0.00037501418,0.00008781249,0.00011208648,0.000101943704,0.0003240862,0.000011283374,0.00044263672,0.00008638941,0.000002310502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007325306,0.00008125053,0.022471558,0.00007120601,0.00004194151,0.000001439274,0.00004993354,0.0000023234254,0.9742384,0.000050273087,0.00018503149,0.002733397],"study_design_scores_gemma":[0.0004673716,0.00015242521,0.00854182,0.00012401181,0.000006893948,0.000005344761,0.00005718831,0.00000392118,0.9879754,0.000042173477,0.002506161,0.000117243726],"about_ca_topic_score_codex":0.00014685169,"about_ca_topic_score_gemma":0.00008223825,"teacher_disagreement_score":0.013929739,"about_ca_system_score_codex":0.000022127166,"about_ca_system_score_gemma":0.00015337493,"threshold_uncertainty_score":0.35808894},"labels":[],"label_agreement":null},{"id":"W2461287631","doi":"10.1039/c6md00274a","title":"Natural products and their derivatives as tRNA synthetase inhibitors and antimicrobial agents","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antimicrobial; Antibiotics; Yeast; Bacteria; Microbiology; Biology; Enzyme; Malaria; Biochemistry; Immunology; Genetics","score_opus":0.008671397957456056,"score_gpt":0.2208608095816079,"score_spread":0.21218941162415184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2461287631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960931,0.0010588384,0.00012729115,0.0021224024,0.00016541028,0.00019395299,0.000016572816,0.0000144513,0.00020799186],"genre_scores_gemma":[0.99781793,0.00040701745,0.0004855296,0.00033971152,0.00019253901,0.000015145163,0.000010986403,0.000021595775,0.0007095187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991652,0.000080003556,0.00012983935,0.00036041715,0.00006194202,0.00020261161],"domain_scores_gemma":[0.9995577,0.000027898697,0.00006050953,0.00024626573,0.00003733954,0.00007031827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017108803,0.00018104671,0.00014809617,0.000028531364,0.00009220954,0.000026344798,0.00011031322,0.00009774876,0.000014520624],"category_scores_gemma":[0.00025182706,0.0001095532,0.000034239125,0.00003864542,0.00014763896,0.0000087454,0.00015527917,0.000046339053,0.000007464497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057640318,0.000022795934,0.00038879964,0.000018791592,0.000034679695,0.000002377374,0.000099989404,1.3114428e-8,0.97038716,0.00003957104,0.0012432933,0.027704885],"study_design_scores_gemma":[0.00036829567,0.00008538073,0.0006089678,0.000055539185,0.000007475525,0.000045774865,0.000044603185,7.9195263e-7,0.9790493,0.00018380691,0.019368716,0.00018130838],"about_ca_topic_score_codex":0.0000065888453,"about_ca_topic_score_gemma":0.0000033299657,"teacher_disagreement_score":0.027523577,"about_ca_system_score_codex":0.000005368799,"about_ca_system_score_gemma":0.000023527764,"threshold_uncertainty_score":0.44674498},"labels":[],"label_agreement":null},{"id":"W2472549195","doi":"10.1039/c6md00342g","title":"Design and synthesis of selective, small molecule inhibitors of coactivator-associated arginine methyltransferase 1 (CARM1)","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Structural Genomics Consortium; Toronto Public Health","funders":"National Institute of General Medical Sciences; Wellcome Trust","keywords":"Coactivator; Methyltransferase; Potency; Chemistry; Arginine; Small molecule; Selectivity; Structure–activity relationship; Stereochemistry; Biochemistry; Combinatorial chemistry; Computational biology; In vitro; Biology; Amino acid; Gene; Methylation; Catalysis","score_opus":0.009830820715130266,"score_gpt":0.218578691517564,"score_spread":0.20874787080243373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2472549195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881549,0.000539226,0.010694237,0.00016890807,0.00004374074,0.00022704154,0.000026788077,0.000011583055,0.00013357143],"genre_scores_gemma":[0.99876034,0.00020072075,0.000856112,0.000012805085,0.000032701035,0.000027878124,0.0000126185105,0.000026986596,0.000069861984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990298,0.00016541638,0.00026643992,0.00025171388,0.0001203559,0.00016628283],"domain_scores_gemma":[0.99928755,0.0001273874,0.00015201773,0.00022463288,0.0001460641,0.00006233199],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028748624,0.00014735312,0.00024921764,0.000064080305,0.000025827763,0.0000029110802,0.00009533389,0.00019444423,0.0000139532385],"category_scores_gemma":[0.00020723295,0.00012009744,0.000074683354,0.00014284655,0.00012402478,0.0000041615745,0.000037341506,0.00005132757,5.666608e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016075523,0.00008551985,0.0016649917,0.000018680568,0.00018608132,4.031907e-7,0.000045392273,0.00003042804,0.9895964,0.00000877173,0.00027504785,0.007927495],"study_design_scores_gemma":[0.0009019328,0.0002369463,0.001801461,0.00006358924,0.00006837185,0.0000026532518,0.000019840882,0.000031500458,0.9965274,0.000037949714,0.00016607202,0.00014233586],"about_ca_topic_score_codex":0.00004922332,"about_ca_topic_score_gemma":0.000027068563,"teacher_disagreement_score":0.010605412,"about_ca_system_score_codex":0.000034235003,"about_ca_system_score_gemma":0.00009040804,"threshold_uncertainty_score":0.48974314},"labels":[],"label_agreement":null},{"id":"W2472992307","doi":"10.1039/c6md00241b","title":"Novel p38α MAP kinase inhibitors identified from yoctoReactor DNA-encoded small molecule library","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Engineering and Physical Sciences Research Council","keywords":"Small molecule; Computational biology; DNA; Kinase; Biology; Combinatorial chemistry; Chemistry; Genetics","score_opus":0.015329803184348043,"score_gpt":0.20439455643016935,"score_spread":0.1890647532458213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2472992307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920548,0.0005808411,0.0022855552,0.00080924813,0.00087611703,0.00021038082,0.00033091975,0.000086240914,0.0027658953],"genre_scores_gemma":[0.98852277,0.000055460474,0.0016804397,0.0006194797,0.0010791738,0.000053510714,0.0005483061,0.00007909154,0.0073617464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838954,0.00006332998,0.0003332525,0.00061646453,0.00018587755,0.00041153704],"domain_scores_gemma":[0.9987075,0.00004626475,0.00013258659,0.00081435725,0.00004368832,0.00025560474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011056185,0.0003057381,0.0002464914,0.000058231577,0.00007605166,0.000056458655,0.00048090235,0.00030042644,0.0003562798],"category_scores_gemma":[0.00010642538,0.00022934032,0.00018648762,0.00007936278,0.00009950266,0.000017599355,0.00037490987,0.00010896209,0.00020405678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008204121,0.00013532145,0.0019876554,0.0000141324645,0.00005795681,0.000019259558,0.000050971797,1.3170165e-7,0.9722897,0.00008954375,0.023415143,0.0018581741],"study_design_scores_gemma":[0.0011222786,0.00010202065,0.0015505699,0.000050388364,0.000023144194,0.0000055287624,0.000032767028,0.000004081549,0.90606236,0.00014505969,0.09056287,0.00033892872],"about_ca_topic_score_codex":0.00007902366,"about_ca_topic_score_gemma":0.000048639195,"teacher_disagreement_score":0.06714773,"about_ca_system_score_codex":0.000018469,"about_ca_system_score_gemma":0.00010117658,"threshold_uncertainty_score":0.9352227},"labels":[],"label_agreement":null},{"id":"W2495494314","doi":"10.1039/c6md00328a","title":"Design, synthesis and evaluation of cytotoxic properties of bisamino glucosylated antitumor ether lipids against cancer cells and cancer stem cells","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; China Scholarship Council; Canadian Cancer Society; University of Manitoba","keywords":"Cancer cell; Ether; Cancer; Cancer stem cell; Chemistry; Amphiphile; Cytotoxic T cell; Apoptosis; Biochemistry; Cytotoxicity; Cancer research; Biology; Combinatorial chemistry; Stereochemistry; In vitro; Organic chemistry; Genetics","score_opus":0.03816353738498118,"score_gpt":0.2626581414273483,"score_spread":0.2244946040423671,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2495494314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9706886,0.028148165,0.00016659645,0.00008076968,0.00038468046,0.00040002473,0.00007482366,0.0000068820327,0.000049458107],"genre_scores_gemma":[0.9824256,0.016635472,0.00016309912,0.0000501815,0.0002657672,0.0001419188,0.0000015506558,0.000027531572,0.00028888427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988082,0.00018530081,0.00027197256,0.0003041389,0.00023520537,0.0001951659],"domain_scores_gemma":[0.99914354,0.000029294057,0.00018608593,0.00027281407,0.0002980107,0.00007024886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054234505,0.00017908202,0.00030718523,0.000055003853,0.000037996346,0.00000877534,0.0001141423,0.00013962106,0.000038404047],"category_scores_gemma":[0.000040138184,0.00012216876,0.000049225662,0.000075369455,0.00025317125,0.000009291292,0.00007421214,0.00004280643,8.2458445e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011244701,0.000037229172,0.00038237058,0.000118010255,0.00009461101,8.463599e-8,0.0001563322,0.000040264935,0.9234513,0.0000014718267,0.00037533787,0.075230554],"study_design_scores_gemma":[0.00083504256,0.00005470054,0.0005409055,0.00023503623,0.00016419179,8.6874905e-7,0.000058088248,0.00016594835,0.9933103,0.000006468328,0.0044525247,0.00017594993],"about_ca_topic_score_codex":0.00014821261,"about_ca_topic_score_gemma":0.000067929905,"teacher_disagreement_score":0.07505461,"about_ca_system_score_codex":0.000025747158,"about_ca_system_score_gemma":0.00019875116,"threshold_uncertainty_score":0.49818972},"labels":[],"label_agreement":null},{"id":"W2500543755","doi":"10.1039/c6md00264a","title":"A combined experimental and computational study on the interaction of nitrogen mustards with DNA","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Energetic Materials and Combustion","field":"Engineering","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Micropharma (Canada)","funders":"","keywords":"Nitrogen; DNA; Chemistry; Work (physics); Biochemistry; Organic chemistry; Engineering","score_opus":0.010934135439904825,"score_gpt":0.22118511854353637,"score_spread":0.21025098310363155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2500543755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99849373,0.000009981822,0.00070808624,0.00013795945,0.0000621536,0.00010911317,0.0000024567207,0.00003209107,0.00044444663],"genre_scores_gemma":[0.9998234,9.073133e-7,0.00009835115,0.000015568232,0.000015679909,0.000025540041,0.0000017065961,0.000008470949,0.000010385561],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996904,0.000023621622,0.00008524921,0.00005555464,0.00009423977,0.000050932606],"domain_scores_gemma":[0.99981135,0.00005973458,0.00001858425,0.0000793993,0.000015446609,0.00001549403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000066791516,0.000060566017,0.00007195081,0.00001834992,0.000022436907,0.000008300262,0.000038628204,0.00001210227,0.000078143494],"category_scores_gemma":[0.00000453127,0.00003060432,0.000008801774,0.000025650712,0.000021015856,0.000029442652,0.0000133842605,0.000022375683,0.0000025770923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076098985,0.0012320646,0.031036546,0.00007796601,0.00043089228,0.000009780833,0.006055961,0.00912657,0.93478864,0.008317868,0.0019187129,0.0062439917],"study_design_scores_gemma":[0.0015602573,0.00073644833,0.015094665,0.00007761648,0.000018395785,0.000004734977,0.0021747749,0.003050004,0.9764159,0.00060518103,0.00012808767,0.00013397631],"about_ca_topic_score_codex":0.000006160362,"about_ca_topic_score_gemma":0.0000015022404,"teacher_disagreement_score":0.041627202,"about_ca_system_score_codex":0.00001801972,"about_ca_system_score_gemma":0.000002693525,"threshold_uncertainty_score":0.12480079},"labels":[],"label_agreement":null},{"id":"W2513072639","doi":"10.1039/c6md90040b","title":"Correction: Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9. See DOI: 10.1039/c6md00159a","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"HSF1; Heat shock factor; Shock (circulatory); Stress (linguistics); Biology; Heat shock protein; Hsp70; Philosophy; Genetics; Medicine; Linguistics; Internal medicine","score_opus":0.010110526273985005,"score_gpt":0.23727349912922696,"score_spread":0.22716297285524195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2513072639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963093,0.0012380087,0.0001661388,0.00055445655,0.00032455643,0.00022759048,0.00011839375,0.000009327593,0.001052252],"genre_scores_gemma":[0.99318826,0.00021344592,0.000027803955,0.000051967076,0.0001479182,0.000018667437,0.000039286104,0.000021547226,0.006291108],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866426,0.000083592226,0.0002982571,0.00035796294,0.0003110901,0.00028483983],"domain_scores_gemma":[0.99907166,0.000045786743,0.00009349451,0.0005240017,0.00014941752,0.00011567083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108883105,0.00020439968,0.00023667028,0.000037099217,0.0000688814,0.000017205579,0.00030857927,0.00020806347,0.00008879746],"category_scores_gemma":[0.0003112359,0.00011515789,0.00017271168,0.0001318041,0.00041669555,0.000010985674,0.00043451937,0.000121228935,0.0000058654095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015282955,0.0001253566,0.00497912,0.000060993643,0.000063281776,0.0000019031581,0.000027770266,0.000001996535,0.98800224,0.000024959289,0.0034514922,0.003108059],"study_design_scores_gemma":[0.00055953354,0.00018026645,0.0025231128,0.0001398006,0.000016294716,0.0000139109625,0.000052505246,0.000006918439,0.9846465,0.000038727692,0.01166069,0.00016171075],"about_ca_topic_score_codex":0.0000916956,"about_ca_topic_score_gemma":0.00004125325,"teacher_disagreement_score":0.008209199,"about_ca_system_score_codex":0.000021436896,"about_ca_system_score_gemma":0.00011530338,"threshold_uncertainty_score":0.46960026},"labels":[],"label_agreement":null},{"id":"W2515987897","doi":"10.1039/c6md00373g","title":"Chemical probes and inhibitors of bromodomains outside the BET family","year":2016,"lang":"en","type":"review","venue":"MedChemComm","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Burnaby Hospital; Simon Fraser University","funders":"Novartis Pharma; Woolf Fisher Trust; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; University of Cambridge; University of Oxford; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; European Federation of Pharmaceutical Industries and Associations; Wellcome; Simon Fraser University; Engineering and Physical Sciences Research Council; AstraZeneca; Pfizer","keywords":"Bromodomain; Acetylation; Epigenetics; Lysine; Computational biology; Chemistry; Biology; Biochemistry; Amino acid; Gene","score_opus":0.022569405387612228,"score_gpt":0.2918795049121337,"score_spread":0.2693100995245215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515987897","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001352309,0.99634403,0.00005174403,0.00014025871,0.0001533378,0.00056723336,0.000070558206,0.000012568186,0.0013079398],"genre_scores_gemma":[0.0012822609,0.9970501,0.00018467291,0.00008618645,0.00047916593,0.000113042566,0.00015935188,0.000047609345,0.0005976254],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985914,0.00013612444,0.0004934017,0.00037801778,0.00018072211,0.00022031594],"domain_scores_gemma":[0.99893034,0.000054669035,0.00029821592,0.000579347,0.000052977128,0.00008448493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028936614,0.0003230601,0.00065572915,0.000048087753,0.000052897798,0.00001892047,0.00038481868,0.00040158132,0.000011742991],"category_scores_gemma":[0.00017559754,0.00017772696,0.00029505743,0.000091328395,0.0003125811,0.0000032970902,0.0003412984,0.00019170418,0.000012337337],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010359738,0.000057090572,0.000012160717,0.0023178363,0.00017771809,0.000001556471,0.000028767321,1.0025077e-8,0.036762238,0.00017865968,0.018645342,0.9418083],"study_design_scores_gemma":[0.00016884289,0.000040602874,0.0000017748202,0.0017360406,0.00008234046,0.000018204297,0.0000112548405,1.2383578e-7,0.08358274,0.000040987063,0.9141023,0.00021478908],"about_ca_topic_score_codex":0.000005943151,"about_ca_topic_score_gemma":0.0000018690896,"teacher_disagreement_score":0.94159347,"about_ca_system_score_codex":0.000018269217,"about_ca_system_score_gemma":0.00013831504,"threshold_uncertainty_score":0.7247495},"labels":[],"label_agreement":null},{"id":"W2520964432","doi":"10.1039/c6md00391e","title":"Mutual regulation and targeting of multidrug resistance and cancer stem phenotype","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"China Scholarship Council; Royal Society of Chemistry; Royal Society","keywords":"Multiple drug resistance; Phenotype; Biology; Cancer; Cancer stem cell; Resistance (ecology); Computational biology; Cancer research; Drug resistance; Genetics; Gene","score_opus":0.012073117807145596,"score_gpt":0.24144192995655522,"score_spread":0.22936881214940963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2520964432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99132144,0.0040492546,0.00091101695,0.0020553023,0.00010108959,0.00018592596,0.000015651476,0.00003647963,0.0013238215],"genre_scores_gemma":[0.9892953,0.000492309,0.0023733652,0.000045751865,0.000071666764,0.000009405566,0.000004238982,0.000016161392,0.0076917694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992799,0.000016266995,0.00021157667,0.00018611086,0.00016461864,0.00014149849],"domain_scores_gemma":[0.9995775,0.00004970708,0.00008694488,0.00013885646,0.00006588174,0.00008111359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018856082,0.00009981643,0.00023472552,0.00003869682,0.000045688023,0.0000035281525,0.000033101354,0.000060109312,0.000069252026],"category_scores_gemma":[0.00001935151,0.000062948675,0.000025561378,0.00006571549,0.00013272621,0.00006181338,0.000014528102,0.00005277514,0.0000020264695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058467186,0.00005087108,0.0451662,0.00055891153,0.000057759135,0.000010040739,0.0011411892,2.8194904e-7,0.9112427,0.0018765184,0.00094479695,0.038366053],"study_design_scores_gemma":[0.0042599454,0.00007954993,0.12075827,0.0015978585,0.00016481621,0.000004602307,0.0004438417,0.00010319106,0.8452889,0.0010695664,0.025941037,0.000288462],"about_ca_topic_score_codex":0.00001839691,"about_ca_topic_score_gemma":0.00008181752,"teacher_disagreement_score":0.07559208,"about_ca_system_score_codex":0.00002450783,"about_ca_system_score_gemma":0.00002734363,"threshold_uncertainty_score":0.25669724},"labels":[],"label_agreement":null},{"id":"W2522515444","doi":"10.1039/c6md00459h","title":"Synthesis and biological evaluation of benzocyclooctene-based and indene-based anticancer agents that function as inhibitors of tubulin polymerization","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cytodiagnostics (Canada)","funders":"National Center for Research Resources; National Cancer Institute; Cancer Prevention and Research Institute of Texas","keywords":"Indene; Tubulin; Colchicine; Combretastatin; Chemistry; Microtubule; Function (biology); Combinatorial chemistry; Polymerization; Pharmacology; Stereochemistry; Biology; Cell biology; Organic chemistry; Genetics; Polymer","score_opus":0.059127719588576114,"score_gpt":0.27393221865821776,"score_spread":0.21480449906964166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2522515444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984607,0.00025372778,0.00018907573,0.00044353295,0.00003621453,0.00009920502,0.000037849175,0.000024691968,0.00045497157],"genre_scores_gemma":[0.99973035,0.00006449533,0.000055108972,0.000051848205,0.000042850057,0.000025377096,0.000011978876,0.000008686509,0.000009318258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880654,0.00014954219,0.00025839164,0.0002921054,0.00035190594,0.00014151855],"domain_scores_gemma":[0.9986734,0.00072799646,0.00024847355,0.00018514812,0.000099909084,0.000065107604],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005705752,0.00015290169,0.00029234824,0.000052890166,0.000045417473,0.000008188156,0.00007623277,0.00022316209,0.0010058889],"category_scores_gemma":[0.0008896601,0.00008953881,0.00006324986,0.00008469847,0.00025194007,0.000059274676,0.000031895677,0.000052589956,0.0000014194909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001762119,0.00012622256,0.24208555,0.000039216226,0.00002238352,1.8143078e-7,0.0000063391676,0.000001777449,0.66207784,0.000010943684,0.000006987484,0.09544635],"study_design_scores_gemma":[0.00062916527,0.00006867518,0.16135833,0.00014976594,0.00008726839,5.536502e-7,0.000024940467,0.0003855431,0.8369564,0.00016367891,0.00006785373,0.000107828826],"about_ca_topic_score_codex":0.00006372183,"about_ca_topic_score_gemma":0.0000051638067,"teacher_disagreement_score":0.17487857,"about_ca_system_score_codex":0.000039741994,"about_ca_system_score_gemma":0.000046994108,"threshold_uncertainty_score":0.9999073},"labels":[],"label_agreement":null},{"id":"W2560029808","doi":"10.1039/c6md00565a","title":"Development of new scaffolds as reversible tissue transglutaminase inhibitors, with improved potency or resistance to glutathione addition","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Blood properties and coagulation","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies; Universities Space Research Association; Fonds de recherche du Québec – Nature et technologies; University of Ottawa","keywords":"Tissue transglutaminase; Glutathione; Potency; Chemistry; Biochemistry; Combinatorial chemistry; Pharmacology; Biophysics; Enzyme; In vitro; Biology","score_opus":0.018641821535672256,"score_gpt":0.2515518589228394,"score_spread":0.23291003738716712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560029808","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9814713,0.00031679578,0.0055570225,0.009653133,0.00009535231,0.00079172384,0.000014161881,0.000083976294,0.0020165043],"genre_scores_gemma":[0.9104362,0.000022314342,0.052248277,0.00030509065,0.00012895596,0.000036998816,0.000023253024,0.000028936392,0.036769938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885786,0.000018340716,0.00033635405,0.00025625332,0.00031034186,0.00022087593],"domain_scores_gemma":[0.99923205,0.0000247915,0.00009537111,0.00029139247,0.00013177488,0.00022463515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015626552,0.00015856995,0.00027435305,0.00008464424,0.00007440808,0.0000071579148,0.00008420608,0.00008871868,0.00067847857],"category_scores_gemma":[0.00005210189,0.00008947276,0.00003276976,0.00027598688,0.000035519504,0.00011941227,0.000024688006,0.000045903358,0.000054324977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034615905,0.0001805882,0.00013437428,0.00020568847,0.00006647067,0.000022818405,0.0022819166,3.2352696e-7,0.7010989,0.00006039566,0.009087059,0.28339985],"study_design_scores_gemma":[0.0023304243,0.0006739518,0.0016245932,0.0012043352,0.00007457113,0.000020746813,0.00025459618,0.0000018891939,0.8754272,0.00004451786,0.118172355,0.00017084315],"about_ca_topic_score_codex":0.00006650015,"about_ca_topic_score_gemma":0.00040543822,"teacher_disagreement_score":0.28322902,"about_ca_system_score_codex":0.0001029645,"about_ca_system_score_gemma":0.0004389398,"threshold_uncertainty_score":0.7428865},"labels":[],"label_agreement":null},{"id":"W2579594233","doi":"10.1039/c6md00607h","title":"Structural features of many circular and leaderless bacteriocins are similar to those in saposins and saposin-like peptides","year":2017,"lang":"en","type":"review","venue":"MedChemComm","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Bacteriocin; Bacteria; Antimicrobial peptides; Microorganism; Antimicrobial; Biology; Microbiology; Chemistry; Peptide; Biochemistry; Computational biology; Genetics","score_opus":0.1190238584628906,"score_gpt":0.3324469586817969,"score_spread":0.21342310021890631,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2579594233","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.098340385,0.90013963,1.62875e-7,0.0003608789,0.00012003702,0.000578428,0.00024981907,0.000015993686,0.0001946524],"genre_scores_gemma":[0.085755646,0.91365975,0.00008577076,0.00010209259,0.000110157256,0.000019210089,0.000113237445,0.0000049554583,0.0001491523],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99851614,0.000102782695,0.00039398778,0.00048604704,0.00016648657,0.0003345702],"domain_scores_gemma":[0.9991827,0.00010193555,0.00032591066,0.00018699376,0.000037256515,0.0001652072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021044815,0.00039550223,0.0012727971,0.0000474692,0.00018645203,0.00015237239,0.00048503382,0.00034609903,0.000017622016],"category_scores_gemma":[0.00004875624,0.00015891506,0.00017092729,0.00014811507,0.00017465118,0.000079425765,0.00035232407,0.00035571514,0.0000017789945],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008709043,0.000033578108,0.00076333026,0.0024694675,0.000054717348,0.000019520727,0.00017118009,6.7074374e-8,0.0012198369,0.000050308012,0.00014792349,0.99506134],"study_design_scores_gemma":[0.00021959477,0.0002562354,0.12277713,0.011508008,0.00024088474,0.00009673686,0.00029497218,0.0000030927117,0.00016471832,0.00009912278,0.8635503,0.00078921684],"about_ca_topic_score_codex":0.00012155517,"about_ca_topic_score_gemma":0.00059966225,"teacher_disagreement_score":0.9942722,"about_ca_system_score_codex":0.000036338188,"about_ca_system_score_gemma":0.000015741964,"threshold_uncertainty_score":0.6480368},"labels":[],"label_agreement":null},{"id":"W2582741531","doi":"10.1039/c7md00014f","title":"Comparison of free-radical inhibiting antioxidant properties of carvedilol and its phenolic metabolites","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Université Pierre et Marie Curie; University of Calgary","keywords":"Carvedilol; Antioxidant; Pharmacology; Chemistry; Heart failure; Drug; Cardiology; Medicine; Biochemistry","score_opus":0.0541709016287443,"score_gpt":0.295704196435877,"score_spread":0.24153329480713268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2582741531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98627007,0.008607875,0.000005671827,0.00032399752,0.000050680665,0.00006261624,0.000043810924,0.00003230129,0.0046029766],"genre_scores_gemma":[0.99920213,0.00013348387,0.00029547847,0.000013708679,0.00013795863,0.000007474443,0.0000026891646,0.00002397913,0.00018311497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985228,0.000024346922,0.00056838436,0.00025114734,0.0003506916,0.00028260628],"domain_scores_gemma":[0.9985857,0.000055561803,0.0005041541,0.00063115516,0.00009869774,0.00012472535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023403304,0.0001943462,0.0006714334,0.000044261502,0.00021577015,0.000048511654,0.0005884576,0.0001818299,0.000116561256],"category_scores_gemma":[0.0007947539,0.00015761814,0.000105497835,0.00004023889,0.00055675925,0.00016698799,0.00035844,0.00030868422,0.0000028069303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022947466,0.00018586272,0.038912628,0.00082794006,0.000059169368,0.0000030741926,0.0004526644,7.5673034e-7,0.9561752,0.00089636946,0.000114322625,0.002349055],"study_design_scores_gemma":[0.0007968002,0.000020223084,0.005601115,0.00061486126,0.00005785012,0.000007452302,0.00025713787,0.0010468318,0.99059975,0.00012932053,0.0006955669,0.00017308559],"about_ca_topic_score_codex":0.00017541842,"about_ca_topic_score_gemma":0.000025676056,"teacher_disagreement_score":0.034424543,"about_ca_system_score_codex":0.000010074523,"about_ca_system_score_gemma":0.000039896513,"threshold_uncertainty_score":0.6427481},"labels":[],"label_agreement":null},{"id":"W2587873904","doi":"10.1039/c6md00691d","title":"N-tert-Prenylation of the indole ring improves the cytotoxicity of a short antagonist G analogue against small cell lung cancer","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre","funders":"Medical Research Council; Biotechnology and Biological Sciences Research Council; Al-Zaytoonah University of Jordan; University of Jordan; Cancer Research UK","keywords":"Prenylation; Indole test; Cytotoxicity; Antagonist; Ring (chemistry); Chemistry; Pharmacology; Stereochemistry; Lung cancer; Combinatorial chemistry; Cancer research; Medicine; Biochemistry; Oncology; Organic chemistry; Receptor; In vitro","score_opus":0.017547556237543973,"score_gpt":0.2730088583302656,"score_spread":0.25546130209272166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2587873904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967519,0.00067164405,0.00054841174,0.00018844476,0.00022019622,0.00024610097,0.000049902555,0.0000030168462,0.0013203862],"genre_scores_gemma":[0.99910265,0.00030227582,0.00007010248,0.00017147447,0.00012344182,0.000030004201,0.000015893005,0.000014833092,0.00016929404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993376,0.000034535744,0.00019132144,0.00017426704,0.00011083265,0.00015140562],"domain_scores_gemma":[0.99890244,0.000008713266,0.00022991742,0.0007581543,0.00007211331,0.000028636934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020087186,0.000115280214,0.00014317565,0.000012475622,0.00023305925,0.000026263197,0.0005837707,0.0000923786,0.000003783928],"category_scores_gemma":[0.000019077774,0.00007383052,0.00012461314,0.000031366275,0.00014255237,0.0000035778799,0.00028042175,0.00009741157,1.2217767e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030907348,0.00003440247,0.00838408,0.000046241694,0.000051396306,1.9578788e-7,0.000120790886,0.000041687286,0.98798805,0.00003779994,0.0000345129,0.0032299086],"study_design_scores_gemma":[0.0002833916,0.00003855668,0.017142419,0.00003343742,0.000042244483,7.208233e-7,0.000049915685,0.0006562606,0.98067033,0.000034477373,0.0009587935,0.00008942684],"about_ca_topic_score_codex":0.00031603329,"about_ca_topic_score_gemma":0.00081314397,"teacher_disagreement_score":0.008758339,"about_ca_system_score_codex":0.000018188528,"about_ca_system_score_gemma":0.00008553228,"threshold_uncertainty_score":0.3010721},"labels":[],"label_agreement":null},{"id":"W2598099381","doi":"10.1039/c7md00052a","title":"Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium; Toronto Public Health","funders":"Novartis Pharma; Ministero dello Sviluppo Economico; Wellcome Trust; Agence Nationale de la Recherche; Wellcome; Imperial College London; Cancer Research UK; Ontario Ministry of Economic Development and Innovation; Alliance Française contre les Maladies Parasitaires; European Federation of Pharmaceutical Industries and Associations; Fundação de Amparo à Pesquisa do Estado de São Paulo; Genome Canada; European Commission; Pfizer","keywords":"Lysine; Methyltransferase; Histone; Biology; Quinazoline; Computational biology; Chemistry; Biochemistry; Methylation; Gene; Stereochemistry; Amino acid","score_opus":0.05188663878967256,"score_gpt":0.31464778519907816,"score_spread":0.2627611464094056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2598099381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98742425,0.00005963734,0.0029805286,0.008312236,0.00009186468,0.000709992,0.00008159498,0.000035198256,0.0003047209],"genre_scores_gemma":[0.9945054,0.000041311378,0.0040420257,0.000020393709,0.000041223055,0.00003877292,0.00017133722,0.000021375095,0.0011181589],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907595,0.00006259094,0.00016447454,0.00028097775,0.00024107854,0.00017493889],"domain_scores_gemma":[0.99899495,0.00016601494,0.00020677826,0.00042215642,0.00010310442,0.00010698474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003148654,0.00019735111,0.00042113135,0.00011181217,0.0004327656,0.000029669678,0.000057732184,0.00015889121,0.00003541492],"category_scores_gemma":[0.00021196288,0.00016772619,0.00009087799,0.000058576254,0.00014196303,0.00033574746,0.000029871822,0.00020938023,0.0000019287195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012185158,0.0007706734,0.21617836,0.00071426475,0.0005224068,0.00002361742,0.0019840205,0.0000041583953,0.7411087,0.00066664256,0.0012424379,0.0355662],"study_design_scores_gemma":[0.0028430605,0.000055752254,0.29562443,0.000092117334,0.00028592703,0.000013604362,0.00003057293,0.0002854522,0.6993965,0.0006733406,0.00056684966,0.00013243462],"about_ca_topic_score_codex":0.00005184692,"about_ca_topic_score_gemma":0.00016017929,"teacher_disagreement_score":0.07944606,"about_ca_system_score_codex":0.00011848432,"about_ca_system_score_gemma":0.000078329555,"threshold_uncertainty_score":0.68396753},"labels":[],"label_agreement":null},{"id":"W2610882654","doi":"10.1039/c7md00113d","title":"Adaptation of a bacterial membrane permeabilization assay for quantitative evaluation of benzalkonium chloride as a membrane-disrupting agent","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Montréal","keywords":"Benzalkonium chloride; Adaptation (eye); Membrane; Chemistry; Chromatography; Biology; Biochemistry","score_opus":0.0968248850705006,"score_gpt":0.36104530078080194,"score_spread":0.2642204157103013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2610882654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911139,0.000031229625,0.0040979176,0.00027287868,0.00013661495,0.0004994524,0.00015327122,0.000023879944,0.0036708382],"genre_scores_gemma":[0.996179,0.000025361522,0.0027482403,0.000012351753,0.00012961272,0.0001736983,0.0004665047,0.000028029193,0.00023721617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985915,0.000045454395,0.00051537337,0.00027855491,0.00039432157,0.00017478627],"domain_scores_gemma":[0.9975972,0.0001958955,0.00090157497,0.00053677574,0.0007174384,0.000051087918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010260239,0.00015926227,0.0002981374,0.000046375753,0.0003146108,0.000046985617,0.0003222782,0.00011635726,0.000890335],"category_scores_gemma":[0.0011766177,0.00015755705,0.00014440136,0.000050444676,0.00012759244,0.00020899333,0.00006854465,0.00007528705,0.000008285569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020827568,0.0001893321,0.0001654366,0.00035491973,0.00007416453,1.4367563e-7,0.0018304312,0.0008714169,0.9865075,0.002892122,0.00004461469,0.0068616695],"study_design_scores_gemma":[0.0014395551,0.000039764385,0.00028242104,0.00012288199,0.0002401319,0.0000013899067,0.0010803117,0.05032009,0.9447089,0.0003545537,0.0012555916,0.00015441202],"about_ca_topic_score_codex":0.0003022446,"about_ca_topic_score_gemma":0.00014253161,"teacher_disagreement_score":0.049448673,"about_ca_system_score_codex":0.00007505253,"about_ca_system_score_gemma":0.00014762326,"threshold_uncertainty_score":0.9748544},"labels":[],"label_agreement":null},{"id":"W2612329522","doi":"10.1039/c7md00381a","title":"A systematic analysis of atomic protein–ligand interactions in the PDB","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":593,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium; Toronto Public Health","funders":"Ontario Ministry of Research, Innovation and Science; Fundação de Amparo à Pesquisa do Estado de São Paulo; Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Novartis Pharma; Wellcome Trust; Genome Canada; Ontario Genomics; Pfizer","keywords":"Protein Data Bank (RCSB PDB); Ligand (biochemistry); Folding (DSP implementation); Stacking; Amide; Hydrogen bond; Chemistry; Protein Data Bank; Protein ligand; Crystallography; Small molecule; Molecule; Stereochemistry; Protein folding; Protein structure; Computational biology; Biology; Biochemistry; Receptor","score_opus":0.04211556220920454,"score_gpt":0.36337965469099537,"score_spread":0.32126409248179083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2612329522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81319267,0.000057850048,0.1826282,0.0016733872,0.0001289669,0.00042199422,0.0000028137235,0.000018493236,0.0018756301],"genre_scores_gemma":[0.9901016,8.912273e-7,0.009652462,0.00006590485,0.000012995213,0.000087133434,0.0000015309741,0.0000032432686,0.000074262774],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9986646,0.0003615362,0.00035435313,0.00019353494,0.00030301814,0.00012294768],"domain_scores_gemma":[0.9974492,0.0007792301,0.00033849088,0.001348623,0.000059685342,0.000024729688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014824873,0.000089092515,0.00032762784,0.00027141575,0.00014997718,0.00023280543,0.001908184,0.000017027693,0.0000051771585],"category_scores_gemma":[0.0006459674,0.00006127195,0.00015388276,0.0005558653,0.000056305704,0.0004001729,0.00027669064,0.00012527936,0.000009973514],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007508005,0.0021466552,0.043633185,0.010171804,0.0059647234,0.00016473928,0.06076351,0.037085775,0.017988896,0.8087165,0.00092057866,0.0123686055],"study_design_scores_gemma":[0.00033032557,0.000020694451,0.115695976,0.0010735882,0.00030245556,0.000013902324,0.00029147213,0.85874075,0.007714012,0.015549834,0.00006833983,0.00019864285],"about_ca_topic_score_codex":0.00017042975,"about_ca_topic_score_gemma":0.00026963983,"teacher_disagreement_score":0.821655,"about_ca_system_score_codex":0.000041706848,"about_ca_system_score_gemma":0.000048736983,"threshold_uncertainty_score":0.35459125},"labels":[],"label_agreement":null},{"id":"W2738142696","doi":"10.1039/c7md00273d","title":"Click chemistry-assisted synthesis of triazolo linked podophyllotoxin conjugates as tubulin polymerization inhibitors","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Plant-derived Lignans Synthesis and Bioactivity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"King Saud University; Institute of Population and Public Health; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Podophyllotoxin; HeLa; Tubulin; Apoptosis; Chemistry; Click chemistry; Colchicine; Conjugate; Cell cycle; Microtubule; Programmed cell death; Cell cycle checkpoint; Docking (animal); Cell; Biochemistry; Cell biology; Stereochemistry; Biology; Combinatorial chemistry","score_opus":0.013406454470922834,"score_gpt":0.2520174765856513,"score_spread":0.23861102211472848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738142696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931344,0.00023635139,0.00005654262,0.00056906126,0.00014015973,0.00020390778,0.00011845419,0.000025402804,0.0055157524],"genre_scores_gemma":[0.9984109,0.00018765265,0.00028814608,0.00007298577,0.0002966103,0.000042186733,0.0001238216,0.000035316134,0.0005423718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984932,0.00009942336,0.00042195132,0.00045594116,0.00022169182,0.0003078014],"domain_scores_gemma":[0.9981573,0.00009080721,0.0005559061,0.00097199756,0.000089450354,0.00013453864],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034815926,0.000282063,0.00043225705,0.0000346029,0.00027154948,0.00007143578,0.0005843199,0.00037593037,0.00009702872],"category_scores_gemma":[0.0010792402,0.0002561638,0.00022227004,0.000052654043,0.00030448954,0.000013341449,0.00021277077,0.0001252349,0.000016786886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000238928,0.00020169262,0.0031125927,0.00005747462,0.00011255303,0.0000048301013,0.000021247643,8.219587e-7,0.984353,0.000008700637,0.00030885826,0.011579265],"study_design_scores_gemma":[0.000564098,0.00009318532,0.008276216,0.000077291705,0.00005946528,0.000018977778,0.000059947724,0.000026962878,0.9864924,0.000020067266,0.0040141367,0.00029724487],"about_ca_topic_score_codex":0.00020271043,"about_ca_topic_score_gemma":0.000021361258,"teacher_disagreement_score":0.01128202,"about_ca_system_score_codex":0.000017823018,"about_ca_system_score_gemma":0.00010823281,"threshold_uncertainty_score":0.99998903},"labels":[],"label_agreement":null},{"id":"W2756423660","doi":"10.1039/c7md00434f","title":"Design, synthesis and preliminary antimicrobial evaluation of N-alkyl chain-tethered C-5 functionalized bis-isatins","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"National Center for Advancing Translational Sciences; National Institutes of Health; Council of Scientific and Industrial Research, India","keywords":"Alkyl; Antimicrobial; Combinatorial chemistry; Chemistry; Chain (unit); Stereochemistry; Organic chemistry; Physics","score_opus":0.12635934815926814,"score_gpt":0.3199826985023783,"score_spread":0.19362335034311018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2756423660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98971426,0.00034913872,0.00040992763,0.0008135821,0.00009450785,0.00023095471,0.000022306254,0.00004223434,0.008323099],"genre_scores_gemma":[0.9981671,0.00006555644,0.0011849987,0.00004109837,0.00013217021,0.000095845804,0.000020521973,0.000016647553,0.00027606144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985279,0.00016398226,0.0003323487,0.00032036426,0.0004742427,0.00018115617],"domain_scores_gemma":[0.9980231,0.00067110773,0.00042866755,0.0005686623,0.00024887375,0.000059602786],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0021977348,0.00017791588,0.00030737993,0.000038507173,0.00031560942,0.000056399553,0.0002811312,0.00020723334,0.003858052],"category_scores_gemma":[0.0032558697,0.00014033863,0.000087204855,0.00003121654,0.0002195665,0.00010272257,0.000113199516,0.00010039459,0.000012021245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003565973,0.00018224797,0.0038479187,0.00008345812,0.00009038428,8.9833054e-7,0.00012697066,0.00006178247,0.8346427,0.000035692203,0.00044961355,0.16012171],"study_design_scores_gemma":[0.0011502932,0.00006147631,0.027133504,0.00016173384,0.00030373264,0.0000086316995,0.00009515292,0.014266524,0.9554462,0.00055258605,0.00059407816,0.00022608161],"about_ca_topic_score_codex":0.00005362904,"about_ca_topic_score_gemma":0.000005217458,"teacher_disagreement_score":0.15989563,"about_ca_system_score_codex":0.00005802465,"about_ca_system_score_gemma":0.00009384908,"threshold_uncertainty_score":0.99705255},"labels":[],"label_agreement":null},{"id":"W2765246760","doi":"10.1039/c7md00267j","title":"Alkyne–azide cycloaddition analogues of dehydrozingerone as potential anti-prostate cancer inhibitors <i>via</i> the PI3K/Akt/NF-kB pathway","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Plant Biotechnology Institute","funders":"Ministry of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy; Ministry of AYUSH, Government of India","keywords":"PI3K/AKT/mTOR pathway; Prostate cancer; Cycloaddition; Protein kinase B; Chemistry; Cancer research; Alkyne; Azide; Combinatorial chemistry; Pharmacology; Stereochemistry; Biochemistry; Medicine; Cancer; Signal transduction; Internal medicine; Organic chemistry","score_opus":0.009331626449674852,"score_gpt":0.25840842500996697,"score_spread":0.2490767985602921,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765246760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948781,0.002030161,0.00019107833,0.0008127605,0.0006075997,0.000274151,0.00030801908,0.00002863112,0.00086947746],"genre_scores_gemma":[0.9975904,0.0003362299,0.00011339159,0.00040773395,0.0007403285,0.00007828717,0.00037298535,0.000048529528,0.00031209856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833816,0.000112857975,0.00036991743,0.00045873347,0.00033623385,0.00038406966],"domain_scores_gemma":[0.9979528,0.000026111658,0.00045851737,0.0012646295,0.00015664524,0.000141273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036981303,0.0002762295,0.0002725761,0.00003565638,0.00047196427,0.00008041046,0.00076463097,0.0001845243,0.00007797958],"category_scores_gemma":[0.0002814254,0.0002227483,0.00022123507,0.0000626035,0.0004853287,0.000016802274,0.0003791954,0.0001873365,0.00002402969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105992185,0.00011179398,0.005978619,0.00003963394,0.00011977401,0.000022190701,0.00012214071,0.00014742077,0.9801631,0.000016751537,0.0061659724,0.007006594],"study_design_scores_gemma":[0.0006869174,0.00012932035,0.003231732,0.00007549489,0.00007991287,0.000014096329,0.000069333786,0.000050070135,0.98585135,0.00034324426,0.0091929585,0.00027555108],"about_ca_topic_score_codex":0.00053218,"about_ca_topic_score_gemma":0.00010748333,"teacher_disagreement_score":0.006731043,"about_ca_system_score_codex":0.000025604424,"about_ca_system_score_gemma":0.00014988559,"threshold_uncertainty_score":0.9083412},"labels":[],"label_agreement":null},{"id":"W2765853467","doi":"10.1039/c7md00334j","title":"New<i>N</i>-(2-phenyl-4-oxo-1,3-thiazolidin-3-yl)-1,2-benzothiazole-3-carboxamides and acetamides as antimicrobial agents","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Benzothiazole; Antimicrobial; Chemistry; Combinatorial chemistry; Medicinal chemistry; Organic chemistry","score_opus":0.03279044920630088,"score_gpt":0.2759014817360447,"score_spread":0.2431110325297438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765853467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92593664,0.00017186854,0.000028910492,0.0023506426,0.0002482609,0.00010141837,0.00003150482,0.00017283068,0.0709579],"genre_scores_gemma":[0.99332625,0.0003065852,0.00096051407,0.00071220496,0.0006794439,0.0000140176835,0.000017565613,0.00004434039,0.0039390875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978899,0.00004673233,0.00037612254,0.0007258674,0.00032088315,0.0006404939],"domain_scores_gemma":[0.99776447,0.00025852612,0.00035517092,0.0011827732,0.00005680573,0.0003822741],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00033678982,0.00046298513,0.00060927443,0.00004235853,0.000808108,0.0004914727,0.0010175958,0.00042380908,0.0027007735],"category_scores_gemma":[0.0007816575,0.00036900848,0.00020674439,0.000046208243,0.00037092788,0.00033397702,0.000745372,0.0004533421,0.000192873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012595023,0.00020965088,0.07955373,0.000118259595,0.00012109154,0.000059847727,0.00017368344,6.055617e-7,0.8478704,0.00043962031,0.01019778,0.06112938],"study_design_scores_gemma":[0.00089821167,0.00003313744,0.038543694,0.00013121906,0.00007450543,0.00006601193,0.000075377466,0.00005832749,0.9100022,0.0015966352,0.047944658,0.000576026],"about_ca_topic_score_codex":0.0008139605,"about_ca_topic_score_gemma":0.00007286758,"teacher_disagreement_score":0.06738958,"about_ca_system_score_codex":0.000061283245,"about_ca_system_score_gemma":0.00006680297,"threshold_uncertainty_score":0.9998762},"labels":[],"label_agreement":null},{"id":"W2784017381","doi":"10.1039/c7md00569e","title":"Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bell (Canada)","funders":"Division of Chemistry; Ministry of Education, India; University of the Western Cape; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Ministry of Earth Sciences; National Research Foundation","keywords":"Indole test; Neuroprotection; Combinatorial chemistry; Disease; Chemistry; Pharmacology; Medicine; Stereochemistry; Internal medicine","score_opus":0.13650369646318375,"score_gpt":0.36884228890499615,"score_spread":0.2323385924418124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2784017381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975341,0.00088506116,0.00025440927,0.0003166015,0.00007587679,0.00043084598,0.000018636105,0.00002180379,0.0004626697],"genre_scores_gemma":[0.998336,0.000046826237,0.00044976702,0.00078968646,0.00019390897,0.00008932779,0.000043741697,0.000016889222,0.000033855416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988041,0.00020359686,0.00019198778,0.00023664362,0.00044705727,0.00011662297],"domain_scores_gemma":[0.99888915,0.00019750306,0.000081091275,0.00020093605,0.00043539432,0.00019595263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029478106,0.00013315119,0.00018730042,0.000084445004,0.00008640467,0.000010363463,0.00004557716,0.00003278412,0.00035543967],"category_scores_gemma":[0.0007698676,0.00011172401,0.000052818912,0.00011485291,0.0001872972,0.00009238359,0.000037630205,0.000049421033,0.000024773459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00598918,0.0031822806,0.25508028,0.00021041313,0.0014467099,0.00007458966,0.0028010702,0.0002537443,0.5348433,0.00009264305,0.00810692,0.18791881],"study_design_scores_gemma":[0.0014116883,0.00011966092,0.29520062,0.00013183855,0.0007917474,0.000004641913,0.00008679503,0.009107957,0.6926991,0.00008910419,0.00023633418,0.00012054861],"about_ca_topic_score_codex":0.000005698157,"about_ca_topic_score_gemma":0.0000013900867,"teacher_disagreement_score":0.18779826,"about_ca_system_score_codex":0.000020829291,"about_ca_system_score_gemma":0.00017575089,"threshold_uncertainty_score":0.4555973},"labels":[],"label_agreement":null},{"id":"W2785993555","doi":"10.1039/c8md00009c","title":"Membrane activity profiling of small molecule <i>B. subtilis</i> growth inhibitors utilizing novel duel-dye fluorescence assay","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Toronto; Toronto Public Health","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Small molecule; Fluorescence; Depolarization; Membrane; Chemistry; Biophysics; Profiling (computer programming); Biochemistry; Biology; Computer science","score_opus":0.020634405570882548,"score_gpt":0.23069644449900328,"score_spread":0.21006203892812073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785993555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912694,0.00017124496,0.0017083471,0.0002797792,0.0007359242,0.0002842858,0.00006733878,0.00012654255,0.005357099],"genre_scores_gemma":[0.99654156,0.000033505126,0.002400375,0.00015554014,0.0001304096,0.000012035007,0.00004440746,0.00003891638,0.0006432373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837637,0.00015303177,0.00038152694,0.00045169605,0.000070335256,0.00056706584],"domain_scores_gemma":[0.99881786,0.00023888987,0.00027376736,0.00040538795,0.00022186023,0.000042258052],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052664377,0.00031368207,0.00050450815,0.000116639894,0.00027126953,0.000022688615,0.00039595427,0.0003177188,0.00017187702],"category_scores_gemma":[0.00026190537,0.00028778307,0.00018089483,0.00025014966,0.000898392,0.00019967498,0.00026768484,0.0004579845,0.000097824806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018017383,0.00028699922,0.0019136172,0.00010644802,0.00009597724,0.0000025639122,0.00039097053,6.2888586e-7,0.9943715,0.00069284666,0.00084799196,0.0011102856],"study_design_scores_gemma":[0.0008018626,0.00014642662,0.00061114575,0.00013475373,0.000045846493,0.000032966913,0.00031589167,0.0000429373,0.99682415,0.000025911093,0.00072220643,0.00029591293],"about_ca_topic_score_codex":0.0005488927,"about_ca_topic_score_gemma":0.000073459225,"teacher_disagreement_score":0.0052721356,"about_ca_system_score_codex":0.000041790674,"about_ca_system_score_gemma":0.000088940695,"threshold_uncertainty_score":0.99995744},"labels":[],"label_agreement":null},{"id":"W2787118989","doi":"10.1039/c8md90011f","title":"Correction: Novel valdecoxib derivatives by ruthenium(<scp>ii</scp>)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes – synthesis and COX-2 inhibition activity","year":2018,"lang":"en","type":"erratum","venue":"MedChemComm","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Nitrile; Cycloaddition; Ruthenium; Valdecoxib; Chemistry; Combinatorial chemistry; 1,3-Dipolar cycloaddition; Medicinal chemistry; Organic chemistry; Catalysis","score_opus":0.01086395891604671,"score_gpt":0.22511962032896113,"score_spread":0.2142556614129144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2787118989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94609493,0.0008863281,0.000876981,0.00031342843,0.00085528125,0.00039025635,0.0044572516,0.00037378434,0.045751743],"genre_scores_gemma":[0.9010724,0.00080368883,0.0006328925,0.00005878045,0.0020559528,0.00082964124,0.0065305834,0.0002338578,0.08778225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99746174,0.00004865851,0.0005597833,0.00093705056,0.0005348527,0.0004579159],"domain_scores_gemma":[0.9963785,0.0011313686,0.0010366326,0.0008826137,0.00035928728,0.00021162348],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021458522,0.0007340038,0.00089718343,0.00010821891,0.00058898394,0.000083943094,0.00034207714,0.0010898205,0.00042044462],"category_scores_gemma":[0.0009438785,0.0007185,0.00018007998,0.00041958666,0.00075417163,0.00025811762,0.00023720974,0.0010971741,0.000011246653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003145176,0.0005375945,0.000048705606,0.0005598252,0.00018541091,0.0000013680742,0.00024564675,3.1850752e-7,0.5813613,0.000005246558,0.41612938,0.00089374505],"study_design_scores_gemma":[0.00045904814,0.000060768845,0.00011017126,0.0012570623,0.00027406373,0.00006164294,0.00040409836,0.0001286755,0.8136535,0.0001149157,0.18315747,0.00031853965],"about_ca_topic_score_codex":0.00013336985,"about_ca_topic_score_gemma":0.000043341202,"teacher_disagreement_score":0.23297192,"about_ca_system_score_codex":0.00016092547,"about_ca_system_score_gemma":0.00016987705,"threshold_uncertainty_score":0.9995266},"labels":[],"label_agreement":null},{"id":"W2797251728","doi":"10.1039/c8md00076j","title":"Design, synthesis and antimicrobial activity of usnic acid derivatives","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Lichen and fungal ecology","field":"Agricultural and Biological Sciences","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Usnic acid; Antimicrobial; Antibacterial activity; Trichoderma viride; Microbiology; Antibiotics; Penicillium; Chemistry; Fusarium; Pseudomonas aeruginosa; Antifungal; Biology; Bacteria; Lichen; Food science; Botany","score_opus":0.03244216829854295,"score_gpt":0.2269920322257071,"score_spread":0.19454986392716417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797251728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99794996,0.000024622452,0.00006517935,0.0010394453,0.000053076088,0.000080028636,0.000007851483,0.000021191185,0.0007586212],"genre_scores_gemma":[0.99910814,0.000018304117,0.00056758855,0.0001450027,0.00010881485,0.00000572561,0.0000011787544,5.502053e-7,0.000044681427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994543,0.00010136778,0.00009002262,0.00015063892,0.000052390904,0.00015128464],"domain_scores_gemma":[0.99947417,0.0003435571,0.00005969498,0.000040000217,0.000038383492,0.000044219876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017931168,0.000079009405,0.00016125235,0.0000066867383,0.00010062904,0.000010954888,0.000126796,0.00007526044,0.00040275554],"category_scores_gemma":[0.00012233351,0.000029963761,0.000029059407,0.00011659118,0.00024059815,0.00006826754,0.000083616564,0.000053414664,0.000016653754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003832083,0.00005035212,0.005227985,0.0000039447445,0.000010767372,4.4090459e-7,0.000100278405,2.5949728e-8,0.96050274,0.000020571086,0.00030051995,0.03374407],"study_design_scores_gemma":[0.000044748354,0.00015427219,0.14292431,0.000006419274,0.000006990629,0.0000025727713,0.000023087505,0.000018691988,0.85615504,0.00007883647,0.00051970495,0.00006536429],"about_ca_topic_score_codex":0.000054838874,"about_ca_topic_score_gemma":0.00008872615,"teacher_disagreement_score":0.13769631,"about_ca_system_score_codex":0.000006574861,"about_ca_system_score_gemma":0.0000050181256,"threshold_uncertainty_score":0.44098908},"labels":[],"label_agreement":null},{"id":"W2802861364","doi":"10.1039/c8md00090e","title":"Isolation, expression and biochemical characterization of recombinant hyoscyamine-6β-hydroxylase from <i>Brugmansia sanguinea</i> – tuning the scopolamine production","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Plant tissue culture and regeneration","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Calgary Laboratory Services; University of Calgary; Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; National Research Foundation of Korea; Deutsche Forschungsgemeinschaft; National Research Foundation","keywords":"Hyoscyamine; Scopolamine; Isolation (microbiology); Recombinant DNA; Biology; Traditional medicine; Botany; Pharmacology; Biochemistry; Microbiology; Medicine; Solanaceae","score_opus":0.0077267938162808,"score_gpt":0.2188665497346788,"score_spread":0.211139755918398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802861364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99575156,0.0007020186,0.0021503023,0.0007356154,0.00040328666,0.00015893465,0.000017738244,0.000011927863,0.00006858802],"genre_scores_gemma":[0.9959151,0.00016265923,0.0006415731,0.00009471924,0.00095021894,0.000011607046,0.0015414644,0.000013151519,0.00066952046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992896,0.000055651686,0.00019724455,0.00025593315,0.00009522334,0.0001063914],"domain_scores_gemma":[0.99944896,0.000008563231,0.0001301692,0.00026172627,0.00011387939,0.00003671803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012421317,0.00011875811,0.00011315327,0.000021791007,0.00013533227,0.000015615291,0.000097202734,0.00011971333,0.000012094213],"category_scores_gemma":[0.00009558156,0.00008116422,0.00002591951,0.00007770487,0.00014251866,0.000011103843,0.0000657115,0.00006048248,0.0000029099956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005177824,0.000035706384,0.0007281217,0.000009873689,0.0000142215185,2.783266e-7,0.00028952042,4.624123e-7,0.99355125,0.0000062361632,0.0045578647,0.00075465767],"study_design_scores_gemma":[0.00022878492,0.00009619916,0.0020497814,0.000052792875,0.000021458394,0.0000124026665,0.000045340905,0.0002270609,0.9812138,0.000018502014,0.015929708,0.00010417812],"about_ca_topic_score_codex":0.000062071405,"about_ca_topic_score_gemma":0.000066290115,"teacher_disagreement_score":0.012337488,"about_ca_system_score_codex":0.0000068858913,"about_ca_system_score_gemma":0.000023038388,"threshold_uncertainty_score":0.33097807},"labels":[],"label_agreement":null},{"id":"W2808117802","doi":"10.1039/c8md00109j","title":"Discovery of a tetrazolyl β-carboline with<i>in vitro</i>and<i>in vivo</i>osteoprotective activity under estrogen-deficient conditions","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and bioactivity of alkaloids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Society of Intestinal Research","funders":"University Grants Commission; Council of Scientific and Industrial Research, India","keywords":"Estrogen; In vivo; In vitro; Pharmacology; Chemistry; Estrogen receptor; Endocrinology; Internal medicine; Biology; Medicine; Biochemistry","score_opus":0.008016705029216725,"score_gpt":0.23870832536332973,"score_spread":0.230691620334113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808117802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977436,0.00020115706,0.0005076988,0.00035893562,0.00004090604,0.00024777252,0.000113961454,0.0000070228593,0.0007789174],"genre_scores_gemma":[0.99921966,0.000027294927,0.00039465431,0.00012401532,0.00008149704,0.00004091352,0.000012344595,0.000019060222,0.00008058453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989478,0.00006535252,0.00017902101,0.00038463826,0.0001544235,0.0002687744],"domain_scores_gemma":[0.99944544,0.000046136443,0.000094163224,0.00031488668,0.000050398914,0.000048956357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021185013,0.00018659965,0.00026975217,0.000097096556,0.000055452303,0.000014067955,0.0001259409,0.00013487412,0.0000094327315],"category_scores_gemma":[0.00004835171,0.00015786903,0.00006535027,0.00018211255,0.00040204223,0.00001456626,0.00009438825,0.00012779266,0.0000013756804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006249623,0.00037493536,0.0026250375,0.000015368565,0.000035365123,0.0000030294357,0.00007063975,0.0000040663417,0.9953804,0.000067512825,0.000023499808,0.00077515777],"study_design_scores_gemma":[0.00082476216,0.00039092326,0.017648673,0.000040252893,0.000015993533,0.000013298205,0.00026153377,0.000054361903,0.98021007,0.00013914474,0.0002102563,0.00019070893],"about_ca_topic_score_codex":0.00025580474,"about_ca_topic_score_gemma":0.0009097098,"teacher_disagreement_score":0.015170333,"about_ca_system_score_codex":0.00003082649,"about_ca_system_score_gemma":0.00007277642,"threshold_uncertainty_score":0.64377123},"labels":[],"label_agreement":null},{"id":"W2808172352","doi":"10.1039/c8md00192h","title":"DIBI, a 3-hydroxypyridin-4-one chelator iron-binding polymer with enhanced antimicrobial activity","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Pneumocystis jirovecii pneumonia detection and treatment","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta; Dalhousie University; Cape Breton University","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Atlantic Canada Opportunities Agency; Cape Breton University","keywords":"Antimicrobial; Chelation; Bioavailability; Chemistry; Combinatorial chemistry; Biology; Pharmacology; Organic chemistry","score_opus":0.012901023604349372,"score_gpt":0.2503390851166647,"score_spread":0.23743806151231533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808172352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988154,0.00003971991,0.00088985683,0.001738241,0.00027825954,0.00045833012,0.000016749382,0.00025161338,0.008173243],"genre_scores_gemma":[0.995536,0.000015177068,0.0004682881,0.0005142119,0.0004602788,0.000047546728,0.00001669174,0.00006612266,0.0028756578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828583,0.00004463,0.00023040998,0.0005350058,0.00038045796,0.00052364013],"domain_scores_gemma":[0.99881935,0.000054720284,0.00014449027,0.00057712424,0.00008792746,0.00031640183],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012038711,0.0003408948,0.0005081232,0.00015415304,0.0002541564,0.000038686194,0.00011664172,0.00015296457,0.00047429674],"category_scores_gemma":[0.000038891307,0.0002735718,0.00012771034,0.00035614305,0.0002554807,0.00013733078,0.0000749246,0.00031626408,0.00058462506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007939827,0.00064133527,0.0021756599,0.000048718877,0.00018994509,0.00005320358,0.00026084014,2.535273e-7,0.9899533,0.000017189466,0.0002338191,0.0056317956],"study_design_scores_gemma":[0.00354479,0.00096613035,0.008890224,0.00017665836,0.00021105286,0.00026451086,0.000023395933,0.0000872827,0.9843722,0.0000047693957,0.0011630078,0.0002959672],"about_ca_topic_score_codex":0.000078715784,"about_ca_topic_score_gemma":0.00006237018,"teacher_disagreement_score":0.007382038,"about_ca_system_score_codex":0.00026653046,"about_ca_system_score_gemma":0.00011443475,"threshold_uncertainty_score":0.9999716},"labels":[],"label_agreement":null},{"id":"W2890620962","doi":"10.1039/c8md00382c","title":"Antiplasmodial imidazopyridazines: structure–activity relationship studies lead to the identification of analogues with improved solubility and hERG profiles","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Medical Research Council; University of Cape Town; South African Medical Research Council; National Research Foundation","keywords":"hERG; Lead (geology); Identification (biology); Solubility; Chemistry; Lead compound; Computational biology; Combinatorial chemistry; Pharmacology; Biology; Biochemistry; Biophysics; In vitro; Organic chemistry","score_opus":0.025082834583540433,"score_gpt":0.28295029869943045,"score_spread":0.25786746411589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890620962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977254,0.00040194916,0.00050470076,0.00084140105,0.00012603149,0.0002569964,0.000065471366,0.000010906101,0.00006708703],"genre_scores_gemma":[0.99892426,0.000040097482,0.00038847394,0.00007482999,0.0003596324,0.000028128912,0.000021306634,0.00001398247,0.00014926794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908215,0.00008169329,0.00023256746,0.00031500997,0.00012225463,0.00016632368],"domain_scores_gemma":[0.9990776,0.00007653268,0.00017023737,0.0004038538,0.00023367349,0.000038086204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031560907,0.00016427727,0.00021038236,0.00003550545,0.00023019186,0.000031605778,0.00015652087,0.00007768387,0.000003156903],"category_scores_gemma":[0.0003600081,0.00009905556,0.000042755142,0.00012678055,0.0004077284,0.000014823085,0.00011494061,0.00007544766,0.0000013395354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028023226,0.000052658914,0.028708952,0.00006571792,0.00009344101,1.7655019e-7,0.00057259196,0.000010836498,0.9671157,0.0000821019,0.000456329,0.002561281],"study_design_scores_gemma":[0.00020023553,0.0002547078,0.108460404,0.000019533041,0.000037619455,0.000005076288,0.0005842615,0.0002009202,0.88912237,0.00019033549,0.0007826125,0.00014191672],"about_ca_topic_score_codex":0.00007015046,"about_ca_topic_score_gemma":0.0009562337,"teacher_disagreement_score":0.07975145,"about_ca_system_score_codex":0.000009655579,"about_ca_system_score_gemma":0.000039352813,"threshold_uncertainty_score":0.40393686},"labels":[],"label_agreement":null},{"id":"W2890754607","doi":"10.1039/c8md00210j","title":"Development of a [<sup>68</sup>Ga]-ghrelin analogue for PET imaging of the ghrelin receptor (GHS-R1a)","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Western University; Ontario Ministry of Research, Innovation and Science; Canada Foundation for Innovation; Prostate Cancer Canada","keywords":"Ghrelin; Receptor; Ligand (biochemistry); Chemistry; Peptide; Pet imaging; Endogeny; Stereochemistry; Biochemistry; Positron emission tomography; Medicine; Nuclear medicine","score_opus":0.030980024275274055,"score_gpt":0.27521662296214694,"score_spread":0.2442365986868729,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890754607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945441,0.000038064867,0.0019042869,0.0013062713,0.00021780959,0.00040019452,0.000033138615,0.000035525394,0.00152063],"genre_scores_gemma":[0.9798184,0.000012078252,0.018879374,0.00046723738,0.000117648655,0.000024231007,0.000009401544,0.000021410387,0.00065019855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983806,0.000088550856,0.0005275448,0.0003296257,0.0003973945,0.0002762578],"domain_scores_gemma":[0.99872875,0.00024390238,0.0002830972,0.00049840956,0.00017716989,0.000068640475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057961897,0.00016226017,0.00026287697,0.00008448655,0.00024254949,0.000018128652,0.0005886252,0.000045082004,0.00025676648],"category_scores_gemma":[0.0005795572,0.00012131706,0.00014019686,0.00034559413,0.0003399049,0.0001032798,0.0001980048,0.00010827856,0.00006716802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016977283,0.00026823697,0.008845782,0.00018110458,0.000022453438,0.0000013122674,0.004255054,0.00011544798,0.95688415,0.001941143,0.013403333,0.013912238],"study_design_scores_gemma":[0.00041669307,0.000033567034,0.0033506732,0.00008809657,0.000010857215,0.000004051968,0.00014193098,0.004128858,0.88024646,0.0002711223,0.11117688,0.00013081825],"about_ca_topic_score_codex":0.000017782862,"about_ca_topic_score_gemma":0.000025212661,"teacher_disagreement_score":0.097773544,"about_ca_system_score_codex":0.000057288882,"about_ca_system_score_gemma":0.00017321295,"threshold_uncertainty_score":0.4947166},"labels":[],"label_agreement":null},{"id":"W2913189051","doi":"10.1039/c9md00036d","title":"Novel carbohydrate modified berberine derivatives: synthesis and<i>in vitro</i>anti-diabetic investigation","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"International Collaboration On Repair Discoveries","funders":"Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Berberine; Alkaloid; Chemistry; Cytotoxicity; Carbohydrate; Derivative (finance); Moiety; In vitro; IC50; Mannose; Stereochemistry; Biochemistry","score_opus":0.02821520002012903,"score_gpt":0.2709801349591726,"score_spread":0.24276493493904358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913189051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99272454,0.00017601144,0.00005300506,0.0029813182,0.00005300237,0.0004988541,0.000008457869,0.000054820073,0.0034499776],"genre_scores_gemma":[0.9964624,0.000068501155,0.0017231718,0.00046834155,0.000063766485,0.0000880921,0.000030128205,0.00003926035,0.0010563144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985438,0.000057092286,0.0003017334,0.00037426775,0.00032079365,0.00040232873],"domain_scores_gemma":[0.9990087,0.00024216922,0.000058669186,0.00040303744,0.00007051608,0.00021687172],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033936344,0.00020580715,0.00047288384,0.00023449851,0.00003971651,0.000028189048,0.00011847569,0.000110095956,0.00011354621],"category_scores_gemma":[0.0002649821,0.00018154226,0.000058509282,0.00046794338,0.00013218448,0.00012936658,0.00012410553,0.00034717467,0.00007869301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009411121,0.00010555388,0.024716387,0.0002233111,0.00004024808,0.000013876165,0.00027251765,0.000018307928,0.97226286,0.000061904386,0.000046596844,0.0021442997],"study_design_scores_gemma":[0.0016220825,0.00007033429,0.092259884,0.00020285188,0.000033863536,0.000022838074,0.00012863564,0.0057495413,0.8990033,0.000092855415,0.00059482345,0.0002189918],"about_ca_topic_score_codex":0.00025474915,"about_ca_topic_score_gemma":0.000014864094,"teacher_disagreement_score":0.073259585,"about_ca_system_score_codex":0.00006794831,"about_ca_system_score_gemma":0.000088812776,"threshold_uncertainty_score":0.74030787},"labels":[],"label_agreement":null},{"id":"W2915738361","doi":"10.1039/c8md90056f","title":"Design, synthesis and antimicrobial activity of usnic acid derivatives","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Lichen and fungal ecology","field":"Agricultural and Biological Sciences","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Usnic acid; Antimicrobial; Chemistry; Combinatorial chemistry; Organic chemistry; Biology; Botany","score_opus":0.03244216829854295,"score_gpt":0.2269920322257071,"score_spread":0.19454986392716417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2915738361","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99794996,0.000024622452,0.00006517935,0.0010394453,0.000053076088,0.000080028636,0.000007851483,0.000021191185,0.0007586212],"genre_scores_gemma":[0.99910814,0.000018304117,0.00056758855,0.0001450027,0.00010881485,0.00000572561,0.0000011787544,5.502053e-7,0.000044681427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994543,0.00010136778,0.00009002262,0.00015063892,0.000052390904,0.00015128464],"domain_scores_gemma":[0.99947417,0.0003435571,0.00005969498,0.000040000217,0.000038383492,0.000044219876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017931168,0.000079009405,0.00016125235,0.0000066867383,0.00010062904,0.000010954888,0.000126796,0.00007526044,0.00040275554],"category_scores_gemma":[0.00012233351,0.000029963761,0.000029059407,0.00011659118,0.00024059815,0.00006826754,0.000083616564,0.000053414664,0.000016653754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003832083,0.00005035212,0.005227985,0.0000039447445,0.000010767372,4.4090459e-7,0.000100278405,2.5949728e-8,0.96050274,0.000020571086,0.00030051995,0.03374407],"study_design_scores_gemma":[0.000044748354,0.00015427219,0.14292431,0.000006419274,0.000006990629,0.0000025727713,0.000023087505,0.000018691988,0.85615504,0.00007883647,0.00051970495,0.00006536429],"about_ca_topic_score_codex":0.000054838874,"about_ca_topic_score_gemma":0.00008872615,"teacher_disagreement_score":0.13769631,"about_ca_system_score_codex":0.000006574861,"about_ca_system_score_gemma":0.0000050181256,"threshold_uncertainty_score":0.44098908},"labels":[],"label_agreement":null},{"id":"W2918247339","doi":"10.1039/c9md00051h","title":"Polybasic peptide–levofloxacin conjugates potentiate fluoroquinolones and other classes of antibiotics against multidrug-resistant Gram-negative bacteria","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Manitoba","keywords":"Levofloxacin; Antibiotics; Multiple drug resistance; Microbiology; Gram-negative bacteria; Bacteria; Biology; Escherichia coli; Biochemistry","score_opus":0.008636359597221168,"score_gpt":0.2359995804414947,"score_spread":0.22736322084427352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918247339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99712014,0.00049445085,0.00006921514,0.00010921607,0.00027014787,0.0003729812,0.00015590509,0.000024133178,0.0013838211],"genre_scores_gemma":[0.9943839,0.00034386365,0.003659331,0.00020282998,0.000091488255,0.0000010490791,0.000091674585,0.000060263206,0.0011656014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982616,0.000120324046,0.00047730343,0.0005420211,0.00019172374,0.0004070583],"domain_scores_gemma":[0.998716,0.000063408224,0.00031877414,0.0006584807,0.00013345906,0.000109874396],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020653776,0.0003469455,0.0004724824,0.00007382629,0.000070002316,0.000049818183,0.00030344882,0.00024854162,0.000078004836],"category_scores_gemma":[0.00013349553,0.00031354258,0.00012822474,0.00011096847,0.0003981669,0.000015899504,0.0002214323,0.00013132737,0.000039581126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025737166,0.00009409662,0.117359295,0.00015355907,0.00014214778,0.0000036695603,0.000099698744,0.000003142688,0.8811077,0.00011730466,0.0003691905,0.00029281442],"study_design_scores_gemma":[0.0010441089,0.00023996315,0.09481186,0.00015531195,0.00003938556,0.0000065714926,0.0004905942,0.00005294738,0.89854497,0.000061415594,0.004190413,0.00036244295],"about_ca_topic_score_codex":0.00005329476,"about_ca_topic_score_gemma":0.000067169385,"teacher_disagreement_score":0.022547442,"about_ca_system_score_codex":0.000018688423,"about_ca_system_score_gemma":0.000052647494,"threshold_uncertainty_score":0.9999317},"labels":[],"label_agreement":null},{"id":"W2918774548","doi":"10.1039/c9md00061e","title":"Isolation and characterization of tambjamine MYP1, a macrocyclic tambjamine analogue from marine bacterium<i>Pseudoalteromonas citrea</i>","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Isolation (microbiology); Bacteria; Biology; Microbiology; Genetics","score_opus":0.007060844976393097,"score_gpt":0.20791038240169987,"score_spread":0.20084953742530678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918774548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961584,0.00010523122,0.000048390615,0.0023022862,0.00019216072,0.00047813758,0.00014131477,0.000048462673,0.00052559306],"genre_scores_gemma":[0.9943318,0.00023304371,0.0009922113,0.0005299356,0.00028182386,0.000002142994,0.0019729494,0.00003212987,0.0016239939],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986695,0.000047050256,0.00043964517,0.00041948538,0.00019836015,0.00022595774],"domain_scores_gemma":[0.9990267,0.00006710268,0.00024209016,0.00043535835,0.00011471677,0.00011399525],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015221347,0.00023936146,0.00055091974,0.00013725646,0.00003538944,0.000022317556,0.000099389545,0.000155397,0.0010433786],"category_scores_gemma":[0.000066030676,0.00019129936,0.0000801465,0.0002489036,0.0000655195,0.00016173963,0.00013754814,0.00018696825,0.000047578545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029875408,0.00012432023,0.054457337,0.00015368282,0.000069504036,0.000005722986,0.00010670653,6.1931225e-8,0.92964953,0.0000122843785,0.00012832705,0.01499374],"study_design_scores_gemma":[0.0010288178,0.00017411217,0.33770847,0.00011652454,0.000100311605,0.000029636294,0.00001484192,0.00023125963,0.6567423,0.000021569705,0.0036718736,0.00016030681],"about_ca_topic_score_codex":0.00031683577,"about_ca_topic_score_gemma":0.000035411475,"teacher_disagreement_score":0.28325114,"about_ca_system_score_codex":0.000037010774,"about_ca_system_score_gemma":0.000021735821,"threshold_uncertainty_score":0.9998698},"labels":[],"label_agreement":null},{"id":"W2922070393","doi":"10.1039/c9md00031c","title":"Tridecaptin-inspired antimicrobial peptides with activity against multidrug-resistant Gram-negative bacteria","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Queen's University Belfast; Royal Society; Queen's University; Wellcome Trust","keywords":"Antimicrobial; Multiple drug resistance; Gram-negative bacteria; Microbiology; Gram; Bacteria; Biology; Antimicrobial peptides; Antibiotics; Genetics; Escherichia coli; Gene","score_opus":0.009280752773765107,"score_gpt":0.21104458576078547,"score_spread":0.20176383298702036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922070393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929575,0.0000656236,0.00007030744,0.0004867039,0.00066594797,0.0006790652,0.0001989251,0.00023751563,0.004638417],"genre_scores_gemma":[0.990378,0.00004476417,0.0010356839,0.00046740426,0.00007475289,0.000025461904,0.00017578472,0.000075039716,0.007723088],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778074,0.00024664644,0.0003814762,0.00069631526,0.000084322244,0.0008105091],"domain_scores_gemma":[0.99852276,0.00030827525,0.00033862298,0.00064254005,0.00012368805,0.000064090615],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002610391,0.0005454616,0.000811364,0.00015127525,0.00033918573,0.00008660469,0.0004328892,0.0003301812,0.0005612682],"category_scores_gemma":[0.000063861866,0.000435386,0.00023619909,0.00023048026,0.0005446195,0.00041767315,0.00020396458,0.00061549834,0.0012776405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017070568,0.00032683977,0.002311368,0.00007420362,0.00031610992,0.000016451293,0.00064012245,0.000015854863,0.98735327,0.00008839669,0.004229082,0.0029212646],"study_design_scores_gemma":[0.003811021,0.00033323152,0.0118456585,0.00021740817,0.00006508248,0.000042341075,0.00055212626,0.000014731454,0.96967846,0.000016648766,0.012745449,0.00067784043],"about_ca_topic_score_codex":0.0005529244,"about_ca_topic_score_gemma":0.00022531163,"teacher_disagreement_score":0.017674789,"about_ca_system_score_codex":0.000114775525,"about_ca_system_score_gemma":0.00013247872,"threshold_uncertainty_score":0.9998098},"labels":[],"label_agreement":null},{"id":"W2926804757","doi":"10.1039/c9md00175a","title":"Mechanism of thienopyridone and iminothienopyridinedione inhibition of protein phosphatases","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mechanism (biology); Phosphatase; Chemistry; Cell biology; Biochemistry; Biology; Phosphorylation; Philosophy; Epistemology","score_opus":0.005926891646091147,"score_gpt":0.2104331119787163,"score_spread":0.20450622033262517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2926804757","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896359,0.008598989,0.00059284543,0.000117138785,0.000058136688,0.00054675055,0.00018181452,0.000010987156,0.00025745953],"genre_scores_gemma":[0.9969321,0.00016698622,0.0023516421,0.00006641483,0.000040276085,0.000036466703,0.00026175915,0.000020705187,0.00012366034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990511,0.00003486521,0.00028846852,0.00027404324,0.00018275132,0.00016878174],"domain_scores_gemma":[0.9991942,0.000015025964,0.00020850085,0.0004243073,0.000101008285,0.000056935267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022766997,0.00015098079,0.00024665485,0.00005893818,0.000024214656,0.0000057846605,0.00012847755,0.00011572031,0.000062225445],"category_scores_gemma":[0.000118490854,0.00014371259,0.00005388321,0.0001187443,0.00012286654,0.000009732685,0.00020880028,0.0000669288,0.0000065048557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014711094,0.00008669814,0.00037759423,0.00018104933,0.000026933083,0.0000011148506,0.000028304941,0.000002146581,0.98381776,0.014082644,0.00025481405,0.0009938037],"study_design_scores_gemma":[0.00084435643,0.00056592585,0.00026121552,0.00009713534,0.000016912034,0.0000071413024,0.00004021926,0.000020240064,0.9958507,0.0010868096,0.0010628892,0.00014650066],"about_ca_topic_score_codex":0.000052295636,"about_ca_topic_score_gemma":0.0000035477947,"teacher_disagreement_score":0.012995835,"about_ca_system_score_codex":0.0000060243688,"about_ca_system_score_gemma":0.000038622202,"threshold_uncertainty_score":0.58604294},"labels":[],"label_agreement":null},{"id":"W2937837366","doi":"10.1039/c9md00161a","title":"Novel antimycobacterial C-21 amide derivatives of the antibiotic fusidic acid: synthesis, pharmacological evaluation and rationalization of media-dependent activity using molecular docking studies in the binding site of human serum albumin","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Medical Research Council; University of Cape Town; South African Medical Research Council; National Research Foundation","keywords":"Fusidic acid; Rationalization (economics); Docking (animal); Antimycobacterial; Chemistry; Antibiotics; Human serum albumin; Amide; Stereochemistry; Combinatorial chemistry; Pharmacology; Microbiology; Biochemistry; Bacteria; Biology; Medicine; Philosophy; Mycobacterium tuberculosis; Tuberculosis","score_opus":0.07773659421497713,"score_gpt":0.36114970496765486,"score_spread":0.2834131107526777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937837366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99836916,0.00032281413,0.00028834926,0.00013166525,0.00016040207,0.00067218824,0.00001872585,0.000004667184,0.00003204674],"genre_scores_gemma":[0.99966323,0.000060469556,0.00019671362,0.000020745321,0.000027738322,0.0000054823736,0.000013534885,0.000009430009,0.000002635098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985686,0.00022751382,0.00035410823,0.00017114355,0.0005585036,0.00012013885],"domain_scores_gemma":[0.99911505,0.00020906625,0.00034660037,0.00016392006,0.00014837748,0.000016978824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012308796,0.00012400448,0.00039480627,0.0000981348,0.000060953236,0.000005901028,0.00009845641,0.00006813585,0.000030993768],"category_scores_gemma":[0.00020724593,0.000074421805,0.000065129265,0.00024678727,0.0001763264,0.00008302573,0.000046975016,0.00011074255,2.0989515e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094987096,0.00018081555,0.05018779,0.00032848542,0.0000929347,0.0000017994939,0.0019878931,0.000114847346,0.94674426,0.00011261217,6.6890374e-7,0.00015288904],"study_design_scores_gemma":[0.0010529711,0.00003870507,0.15086474,0.00053948263,0.00029121345,0.000004719303,0.0009858606,0.0009567935,0.8451651,0.000039814968,7.0771745e-7,0.000059904552],"about_ca_topic_score_codex":0.000019211471,"about_ca_topic_score_gemma":0.000029791938,"teacher_disagreement_score":0.10157919,"about_ca_system_score_codex":0.000051809468,"about_ca_system_score_gemma":0.00006339181,"threshold_uncertainty_score":0.30348334},"labels":[],"label_agreement":null},{"id":"W2943239879","doi":"10.1039/c9md00088g","title":"Anthranilic amide and imidazobenzothiadiazole compounds disrupt<i>Mycobacterium tuberculosis</i>membrane potential","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Eli Lilly and Company; Bill and Melinda Gates Foundation","keywords":"Amide; Mycobacterium tuberculosis; Chemistry; Anthranilic acid; Membrane; Combinatorial chemistry; Tuberculosis; Stereochemistry; Biochemistry; Medicine","score_opus":0.010914591921448951,"score_gpt":0.28172751104466026,"score_spread":0.2708129191232113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943239879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9773196,0.0010740499,0.000027433307,0.010565332,0.0004029879,0.00057005585,0.00002526968,0.00014576093,0.009869519],"genre_scores_gemma":[0.9938708,0.00092667615,0.00035269448,0.0032514227,0.00034335628,0.000033866654,0.00014736307,0.000055733304,0.0010180939],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9974595,0.00017814885,0.00048072616,0.00060576294,0.00041575957,0.0008601378],"domain_scores_gemma":[0.9982298,0.00025435543,0.0000841308,0.0007157751,0.00010656835,0.0006093509],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006234088,0.0003346161,0.00083944,0.00019253686,0.0001284649,0.000049597456,0.00019613616,0.00026455792,0.0011535526],"category_scores_gemma":[0.00020622433,0.00027875957,0.00020617394,0.00023554536,0.00025714122,0.00018711896,0.00021467007,0.00063549203,0.00053651957],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005538773,0.00030004597,0.28921407,0.00046791372,0.00027370488,0.00010995979,0.0002047542,0.000009589436,0.69632494,0.00021535123,0.009599248,0.0027265626],"study_design_scores_gemma":[0.0070447857,0.0010291953,0.79600257,0.00026296507,0.00031111555,0.0018626451,0.00041511664,0.005171624,0.13541058,0.00028030286,0.0513651,0.0008440081],"about_ca_topic_score_codex":0.0003528187,"about_ca_topic_score_gemma":0.000042675627,"teacher_disagreement_score":0.56091434,"about_ca_system_score_codex":0.00009717302,"about_ca_system_score_gemma":0.00008043421,"threshold_uncertainty_score":0.99996644},"labels":[],"label_agreement":null},{"id":"W2944173178","doi":"10.1039/c9md00138g","title":"Fungal natural alkaloid schizocommunin activates the aryl hydrocarbon receptor pathway","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Hospital for Sick Children; University of Ottawa","keywords":"Alkaloid; Aryl hydrocarbon receptor; Aryl; Chemistry; Hydrocarbon; Stereochemistry; Organic chemistry; Biochemistry","score_opus":0.013202178184679881,"score_gpt":0.2716307960179219,"score_spread":0.258428617833242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944173178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84671974,0.003308008,0.0000031171999,0.0050471774,0.0027488715,0.00034700547,0.000011319656,0.0001258585,0.14168887],"genre_scores_gemma":[0.98878354,0.00004547697,0.00008019728,0.0011740804,0.00033355056,0.00009516603,0.000023400193,0.000045099892,0.0094195],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984051,0.0001610752,0.0002825943,0.0003680593,0.00026177333,0.0005214114],"domain_scores_gemma":[0.99815893,0.0004564121,0.00012980505,0.0011333156,0.000048825754,0.0000727355],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004899057,0.00028800507,0.0003289299,0.0000663046,0.00025584738,0.000048614576,0.0007641782,0.00013756027,0.0012295957],"category_scores_gemma":[0.000049749295,0.00018767233,0.00016364436,0.00024467913,0.0001387456,0.00008263422,0.00028372367,0.0007793884,0.0025378577],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014323747,0.0016675129,0.14849389,0.000107377375,0.0022950326,0.000035682675,0.03878986,0.000010483481,0.32750815,0.070865326,0.31700623,0.09178808],"study_design_scores_gemma":[0.0035689296,0.0003522857,0.07073552,0.00012300187,0.00005561209,0.000056236964,0.011962402,0.00019566638,0.073901646,0.0026951807,0.8351469,0.001206587],"about_ca_topic_score_codex":0.00019439976,"about_ca_topic_score_gemma":0.000050317267,"teacher_disagreement_score":0.5181407,"about_ca_system_score_codex":0.000045363715,"about_ca_system_score_gemma":0.000022833954,"threshold_uncertainty_score":0.99968344},"labels":[],"label_agreement":null},{"id":"W2950932397","doi":"10.1039/c9md00146h","title":"On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome","year":2019,"lang":"en","type":"review","venue":"MedChemComm","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Biotech (Canada); University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Secretion; Virulence; Computational biology; Biology; Cell biology; Biochemistry; Gene","score_opus":0.04958219378180303,"score_gpt":0.33410083000217294,"score_spread":0.28451863622036994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950932397","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02405122,0.97303176,0.00029061484,0.00012144453,0.0003729187,0.0017347969,0.00003624948,0.000018140188,0.00034287933],"genre_scores_gemma":[0.1539384,0.8433093,0.0009387423,0.00051019026,0.00032418323,0.00028810021,0.00028243873,0.0001228897,0.0002857823],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99795514,0.00042353064,0.000477859,0.00039881637,0.00041599368,0.00032867873],"domain_scores_gemma":[0.99843144,0.00020076321,0.0003246859,0.00079039746,0.00020592022,0.00004681155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007979766,0.00036735387,0.00069520035,0.000057603043,0.00023157221,0.000031773463,0.0008427547,0.00024107381,0.000011653738],"category_scores_gemma":[0.00025181388,0.00018813464,0.00017834576,0.0003464808,0.000095192554,0.0000016149706,0.0003710098,0.00039841072,0.000021796699],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002689304,0.000224172,0.00014069656,0.035778183,0.0033632123,0.0000058170253,0.0014554667,0.00023724748,0.11185544,0.0008814012,0.004313571,0.84147584],"study_design_scores_gemma":[0.0001641513,0.00023560983,0.000038415175,0.003193054,0.00017386433,0.0000031191878,0.00020546095,0.00006375611,0.013500696,0.000003337878,0.9820475,0.00037106266],"about_ca_topic_score_codex":0.000010850131,"about_ca_topic_score_gemma":0.000011764859,"teacher_disagreement_score":0.9777339,"about_ca_system_score_codex":0.00010326033,"about_ca_system_score_gemma":0.0006046906,"threshold_uncertainty_score":0.7671908},"labels":[],"label_agreement":null},{"id":"W2981087014","doi":"10.1039/c9md00400a","title":"Recent developments on zinc(<scp>ii</scp>) metal–organic framework nanocarriers for physiological pH-responsive drug delivery","year":2019,"lang":"en","type":"review","venue":"MedChemComm","topic":"Metal-Organic Frameworks: Synthesis and Applications","field":"Chemistry","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"Shenzhen Peacock Plan; Natural Science Foundation of Guangdong Province","keywords":"Nanocarriers; Zinc; Chemistry; Drug delivery; Drug; Metal; Nanotechnology; Pharmacology; Materials science; Organic chemistry; Medicine","score_opus":0.05737543562266674,"score_gpt":0.30788699804420383,"score_spread":0.2505115624215371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981087014","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021115523,0.99131894,0.00021939467,0.0001955149,0.00075414556,0.0017343549,0.00047713102,0.00028738356,0.0029015986],"genre_scores_gemma":[0.00021318988,0.98226583,0.005052405,0.00063513615,0.0006569226,0.0019217131,0.0008705396,0.00033769035,0.008046558],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99428034,0.00027641837,0.0015968599,0.0018161046,0.0007633095,0.0012669581],"domain_scores_gemma":[0.98960674,0.0060880515,0.0012801462,0.0022645446,0.00027875623,0.0004817736],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.00085183844,0.0014726511,0.0037014598,0.00020134664,0.00064457534,0.00012123364,0.0020812151,0.002040294,0.0016761625],"category_scores_gemma":[0.0048104045,0.0011753353,0.0014864048,0.0007577263,0.00019775369,0.00009126575,0.00074652646,0.0021558467,0.0014037082],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027518166,0.0006699301,0.0000017019056,0.008014509,0.0019354358,0.000008943999,0.00033210753,0.0000010561237,0.0035667322,0.0012313462,0.036639635,0.9475711],"study_design_scores_gemma":[0.00027239323,0.00004359985,0.0000014299349,0.008628028,0.0014302148,0.000011792319,0.00018812226,0.0000049834366,0.02972794,0.0009200689,0.95814735,0.00062410336],"about_ca_topic_score_codex":0.0000026748269,"about_ca_topic_score_gemma":0.0000017209076,"teacher_disagreement_score":0.946947,"about_ca_system_score_codex":0.00072956755,"about_ca_system_score_gemma":0.0008933234,"threshold_uncertainty_score":0.9998023},"labels":[],"label_agreement":null},{"id":"W2986608952","doi":"10.1039/c9md00402e","title":"High affinity rigidified AT<sub>2</sub> receptor ligands with indane scaffolds","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning; Vetenskapsrådet; Stiftelsen för Strategisk Forskning; Alzheimer's Society","keywords":"Indane; Chemistry; Agonist; Stereochemistry; Receptor; Combinatorial chemistry; Side chain; Organic chemistry; Biochemistry; Polymer","score_opus":0.004533298004989204,"score_gpt":0.185417161003706,"score_spread":0.1808838629987168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2986608952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976737,0.00020537397,0.00022611438,0.0001573422,0.0004241726,0.00026711216,0.000020927002,0.000043949178,0.0009813065],"genre_scores_gemma":[0.99655366,0.00011197558,0.0010267152,0.00031686158,0.00032258514,0.000032496115,0.00031160406,0.000059993556,0.0012641135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998477,0.000046741,0.00024989387,0.00053171936,0.00027615507,0.00041849745],"domain_scores_gemma":[0.9989605,0.000022152048,0.00013533227,0.00061216805,0.00009828761,0.00017153952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029968962,0.00029090545,0.0003086392,0.000048355534,0.000128354,0.00004020982,0.00029831482,0.0002942797,0.00049418746],"category_scores_gemma":[0.000024261235,0.00024111626,0.00011410682,0.0001415482,0.00005825285,0.0000073666774,0.00020114826,0.00012421905,0.00032320747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024866068,0.00006891701,0.001637528,0.000025701598,0.00007238636,0.0000028420516,0.00005541356,0.000035885172,0.99376935,0.00013315599,0.002761833,0.0011883014],"study_design_scores_gemma":[0.0011044923,0.0005468242,0.00031074343,0.000035554243,0.000020541042,0.000014638674,0.000057140696,0.000012879122,0.9834874,0.000045046934,0.0139949955,0.00036972328],"about_ca_topic_score_codex":0.00001959123,"about_ca_topic_score_gemma":0.00003872847,"teacher_disagreement_score":0.011233163,"about_ca_system_score_codex":0.00004268519,"about_ca_system_score_gemma":0.000074227486,"threshold_uncertainty_score":0.9832435},"labels":[],"label_agreement":null},{"id":"W4242633767","doi":"10.1039/c6md90011a","title":"Correction: Continuous flow photochemistry as an enabling synthetic technology: synthesis of substituted-6(5H)-phenanthridinones for use as poly(ADP-ribose) polymerase inhibitors","year":2016,"lang":"en","type":"article","venue":"MedChemComm","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"","keywords":"Continuous flow; Polymerase; Poly ADP ribose polymerase; Combinatorial chemistry; Chemistry; Ribose; Computational biology; Stereochemistry; Biochemistry; Enzyme; Biology; Biochemical engineering; Engineering","score_opus":0.027731541008831313,"score_gpt":0.2686978765808376,"score_spread":0.24096633557200628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242633767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912555,0.002135011,0.00063436665,0.0026195396,0.00096351595,0.00087762123,0.00008039849,0.00031427486,0.001119762],"genre_scores_gemma":[0.99387103,0.00017470361,0.002434282,0.00013140366,0.0004377535,0.00037579643,0.000016371394,0.00008905279,0.002469581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99752945,0.00009242246,0.0007347396,0.00065768685,0.00041085572,0.00057483383],"domain_scores_gemma":[0.9969035,0.0010866525,0.0003239816,0.0010643592,0.00034232452,0.00027921324],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000498947,0.0004489069,0.0009973665,0.00031421447,0.00024336243,0.0000483471,0.00033651746,0.0003638195,0.0005873043],"category_scores_gemma":[0.004474923,0.00029462355,0.00032559884,0.0003482727,0.00058411347,0.00027137902,0.000104973224,0.00021578198,0.000054905777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010217694,0.00038832988,0.0016238267,0.00020567214,0.00018310295,0.000024679803,0.00012638689,3.0468038e-7,0.89883536,0.00011277837,0.000827738,0.09665003],"study_design_scores_gemma":[0.0009917496,0.00039616242,0.00007817936,0.0016228718,0.00033341142,0.00036964292,0.00065680844,0.0001663696,0.98279166,0.00018698836,0.012007869,0.0003982872],"about_ca_topic_score_codex":0.00030335312,"about_ca_topic_score_gemma":0.00001673937,"teacher_disagreement_score":0.09625173,"about_ca_system_score_codex":0.00009272758,"about_ca_system_score_gemma":0.00022516653,"threshold_uncertainty_score":0.9999506},"labels":[],"label_agreement":null},{"id":"W4243041475","doi":"10.1039/c7md00575j","title":"Novel valdecoxib derivatives by ruthenium(<scp>ii</scp>)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes – synthesis and COX-2 inhibition activity","year":2018,"lang":"en","type":"article","venue":"MedChemComm","topic":"Synthesis and Catalytic Reactions","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"European Social Fund; Fundación Ramón Areces","keywords":"Nitrile; Ruthenium; Cycloaddition; Chemistry; Valdecoxib; Combinatorial chemistry; 1,3-Dipolar cycloaddition; Organic chemistry; Catalysis","score_opus":0.011937555035532536,"score_gpt":0.21787576789454766,"score_spread":0.20593821285901512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243041475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99170494,0.0001625888,0.0011137027,0.00016645368,0.000028531931,0.00012420405,0.00054527295,0.00010979532,0.0060444903],"genre_scores_gemma":[0.998309,0.00006621084,0.00080831186,0.000025870355,0.00014439115,0.00009503775,0.00011695333,0.000048960006,0.00038526865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855286,0.00003821225,0.00030699308,0.000438499,0.00034787075,0.0003155676],"domain_scores_gemma":[0.9979226,0.0009339889,0.00035431096,0.000472797,0.00018260143,0.00013370984],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023181902,0.0003086594,0.0004291423,0.00009427633,0.00034524812,0.00004925754,0.00015511642,0.00021166605,0.00028240832],"category_scores_gemma":[0.0007392332,0.00026533776,0.000090569265,0.00024097231,0.00052924396,0.00034633625,0.000098901575,0.00019373743,0.0000122796155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003615533,0.0005187008,0.0006454701,0.00010691687,0.00014978561,0.0000011074327,0.00058471045,2.151263e-7,0.98983234,0.00004249769,0.0017320266,0.006350089],"study_design_scores_gemma":[0.00048570434,0.00008264624,0.0024574755,0.0002782733,0.00014013362,0.000042932083,0.0009977145,0.00009218993,0.98960537,0.00020038034,0.0054573473,0.00015986233],"about_ca_topic_score_codex":0.00023178116,"about_ca_topic_score_gemma":0.00004031198,"teacher_disagreement_score":0.006604036,"about_ca_system_score_codex":0.00006633567,"about_ca_system_score_gemma":0.000047546524,"threshold_uncertainty_score":0.99997985},"labels":[],"label_agreement":null}]}