{"meta":{"query_hash":"fa310a3c280b","filters":{"venue":"Molecular Pharmacology"},"cohort_total":370,"direct_labels_cover":0,"predictions_cover":370,"exported":370,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/fa310a3c280b","api":"https://metacan.xera.ac/api/v1/cohort?venue=Molecular+Pharmacology"},"results":[{"id":"W1794816422","doi":"10.1124/mol.115.098228","title":"Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neonatal Health and Biochemistry","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of Environmental Health Sciences; National Institutes of Health; National Cancer Institute; Fundação para a Ciência e a Tecnologia; National Institute of General Medical Sciences; Universidade de Lisboa","keywords":"Kernicterus; Cerebellum; Central nervous system; Encephalopathy; Pons; Myelin basic protein; Myelin; White matter; Bilirubin; Medicine; Endocrinology; Internal medicine; Pathology; Biology; Magnetic resonance imaging","score_opus":0.019679400398279184,"score_gpt":0.3168199981367097,"score_spread":0.2971405977384305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1794816422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948523,0.0012725708,0.000043059477,0.0020930376,0.0002540835,0.0003018088,0.000043240943,0.00007120351,0.0010687123],"genre_scores_gemma":[0.9957683,0.000026346612,0.0013186642,0.0021384782,0.00031400015,0.000021335973,0.00027983135,0.000018867899,0.00011415577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884915,0.000103921106,0.00021343307,0.00037123397,0.00020061534,0.00026165982],"domain_scores_gemma":[0.9990779,0.00007707769,0.000085964675,0.00015770517,0.00014959462,0.0004517705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026299496,0.00014934807,0.00023470452,0.00004791008,0.00005115332,0.000007345025,0.00006172678,0.0001770047,0.00005434436],"category_scores_gemma":[0.00027025,0.00014513811,0.000038228314,0.00011402108,0.00007987583,0.00005429455,0.00008194576,0.00031981498,0.000017940642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013673467,0.000075390366,0.0009227991,0.000068278845,0.000033725824,0.00053973874,0.00009289901,8.9275267e-7,0.97383803,0.0000034609552,0.0019153566,0.021142054],"study_design_scores_gemma":[0.0060610063,0.00017724931,0.004314215,0.000030895084,0.00012943272,0.0003691416,0.00010684791,0.0006934035,0.98201394,0.0001204066,0.005820706,0.00016278065],"about_ca_topic_score_codex":0.0005089485,"about_ca_topic_score_gemma":0.0000044679164,"teacher_disagreement_score":0.020979274,"about_ca_system_score_codex":0.00012919563,"about_ca_system_score_gemma":0.0002920198,"threshold_uncertainty_score":0.59185606},"labels":[],"label_agreement":null},{"id":"W1821749400","doi":"10.1124/mol.59.4.814","title":"Distinct Functional and Pharmacological Properties of Tonic and Quantal Inhibitory Postsynaptic Currents Mediated by γ-Aminobutyric Acid<sub>A</sub>Receptors in Hippocampal Neurons","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":360,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"GABAA receptor; Inhibitory postsynaptic potential; Neuroscience; Bicuculline; Chemistry; Postsynaptic Current; Tonic (physiology); Neurotransmission; Hippocampal formation; Postsynaptic potential; Excitatory postsynaptic potential; GABAergic; GABA receptor antagonist; Receptor; Biology; Biochemistry","score_opus":0.03969389171426831,"score_gpt":0.29820095122905044,"score_spread":0.25850705951478214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1821749400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963773,0.00093664427,0.000014044404,0.00079272146,0.0010034661,0.0007367302,0.000036696325,0.00007067345,0.000031713495],"genre_scores_gemma":[0.99632466,0.0014542573,0.0000017960804,0.0019682471,0.000046998,0.00013783787,0.0000049386804,0.00003587353,0.000025370806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959309,0.001178747,0.00050317025,0.0010355741,0.0004900208,0.0008615829],"domain_scores_gemma":[0.99895716,0.00036375603,0.00015384963,0.00012144254,0.00005517927,0.00034860434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003122361,0.00037254795,0.0004467225,0.0004049174,0.00022246563,0.00003350526,0.00035211828,0.0001593298,0.00014157011],"category_scores_gemma":[0.00033087717,0.0003386517,0.000070383045,0.00078332535,0.0017536267,0.00026564876,0.00045891304,0.00083761435,0.00003204783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066862407,0.0006709208,0.0062802867,0.000038466784,0.000017015478,0.0007924572,0.00005885024,0.000013952423,0.9899043,0.000011281471,0.00061491336,0.00092892005],"study_design_scores_gemma":[0.0027035396,0.00067271997,0.0037559252,0.000007534044,0.00008937322,0.00042692703,0.000018100765,0.0028947496,0.9888106,0.000014745706,0.0003186457,0.00028713644],"about_ca_topic_score_codex":0.0000059745385,"about_ca_topic_score_gemma":0.00000212058,"teacher_disagreement_score":0.0030262633,"about_ca_system_score_codex":0.00006865672,"about_ca_system_score_gemma":0.00014062587,"threshold_uncertainty_score":0.99990654},"labels":[],"label_agreement":null},{"id":"W1831037246","doi":"10.1124/mol.59.3.636","title":"Glucuronidation of the Nonsteroidal Antiestrogen EM-652 (SCH 57068), by Human and Monkey Steroid Conjugating UDP-Glucuronosyltransferase Enzymes","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"","keywords":"Glucuronidation; Microsome; Glucuronide; Enzyme; Glucuronosyltransferase; Metabolite; In vivo; Biology; Metabolism; Steroid; Chemistry; Biochemistry; Internal medicine; Endocrinology; Hormone; Medicine","score_opus":0.0033223964127046058,"score_gpt":0.24006795178849613,"score_spread":0.23674555537579153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1831037246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99229896,0.0056649433,0.00070329366,0.0002510865,0.00021586932,0.0004642382,0.000030097903,0.000018636327,0.00035287585],"genre_scores_gemma":[0.99846905,0.00041706357,0.00008384285,0.00058733125,0.000081079226,0.000031284864,0.00011409748,0.000039803857,0.0001764222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838763,0.00033152555,0.0003379194,0.00041966356,0.00015432313,0.0003689288],"domain_scores_gemma":[0.9993758,0.000019241217,0.00014979481,0.00027169645,0.00006881388,0.00011461541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001698521,0.0002607251,0.00024298448,0.000050377083,0.00018844297,0.0000240427,0.00027653849,0.0002486776,0.000049393147],"category_scores_gemma":[0.000018261553,0.00022136905,0.00013044289,0.00013106647,0.00025708968,0.000009991528,0.00016083379,0.00024572067,0.0000037858124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010560597,0.000108276356,0.005208098,0.000025588248,0.00019546127,0.000020810614,0.000078190445,0.000075224314,0.99171287,0.00006776677,0.001003058,0.00139905],"study_design_scores_gemma":[0.0018310652,0.00048877235,0.00062649196,0.00001342392,0.00014176551,0.000103245206,0.000054321958,0.00012366811,0.991522,0.000020102842,0.0048533683,0.00022174604],"about_ca_topic_score_codex":0.000024159619,"about_ca_topic_score_gemma":0.0000049748573,"teacher_disagreement_score":0.006170116,"about_ca_system_score_codex":0.000012390323,"about_ca_system_score_gemma":0.000053330692,"threshold_uncertainty_score":0.90271676},"labels":[],"label_agreement":null},{"id":"W1838732593","doi":"10.1124/mol.58.4.747","title":"Duplications and Defects in the<i>CYP2A6</i>Gene: Identification, Genotyping, and In Vivo Effects on Smoking","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":229,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"CYP2A6; Allele; Genotyping; Nicotine; Cotinine; Genotype; Genetics; Biology; Gene","score_opus":0.028214784637219735,"score_gpt":0.3774294290619727,"score_spread":0.349214644424753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1838732593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877643,0.0064941063,0.00003986193,0.0018905463,0.00045887835,0.000953292,0.000020446909,0.000037058562,0.0023414844],"genre_scores_gemma":[0.9794073,0.003165412,0.000049858558,0.01663227,0.00014858342,0.00041537406,0.00001109659,0.000031311276,0.00013879078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99707955,0.001238332,0.00042066688,0.0005669939,0.00015395465,0.0005405056],"domain_scores_gemma":[0.99894565,0.0005279784,0.000094978575,0.0002283861,0.000034835393,0.0001681965],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010822978,0.0002840764,0.00029174198,0.00028804687,0.00022106136,0.000037664573,0.00033550712,0.00025514234,0.0005071797],"category_scores_gemma":[0.000041835538,0.00026819715,0.00005393857,0.00046763316,0.0002044296,0.000070352355,0.0000660767,0.0007959488,0.000043642463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021948676,0.0003547591,0.008793759,0.000055612978,0.00008200543,0.0002642075,0.001144136,0.0015223313,0.950938,0.0009294019,0.001391081,0.03430521],"study_design_scores_gemma":[0.0047423365,0.0000840389,0.055260077,0.000015363583,0.00029011164,0.00009992456,0.0000360664,0.0024639305,0.79855394,0.0015909588,0.13643365,0.0004295846],"about_ca_topic_score_codex":0.000026204632,"about_ca_topic_score_gemma":0.000020304095,"teacher_disagreement_score":0.15238404,"about_ca_system_score_codex":0.00004273389,"about_ca_system_score_gemma":0.000045306046,"threshold_uncertainty_score":0.99997705},"labels":[],"label_agreement":null},{"id":"W1847746464","doi":"10.1124/mol.59.3.427","title":"Discovery of a Novel Member of the Histamine Receptor Family","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":349,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; U.S. Public Health Service","keywords":"Histamine receptor; Histamine H4 receptor; Receptor; G protein-coupled receptor; Biology; Molecular biology; Histamine H2 receptor; Complementary DNA; Histamine H3 receptor; Histamine H1 receptor; Genetics; Gene; Agonist; Antagonist","score_opus":0.014282099663764154,"score_gpt":0.25191083788744617,"score_spread":0.23762873822368202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1847746464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98705995,0.0026186414,0.0017486743,0.00043999733,0.0014367435,0.00024066056,0.000069916765,0.000013396765,0.0063720252],"genre_scores_gemma":[0.98863757,0.00011356486,0.00010716157,0.00059858133,0.000022869908,0.000015820011,0.000029914641,0.000016565611,0.010457968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990242,0.0001372688,0.00033988678,0.00020692048,0.00004325968,0.0002484781],"domain_scores_gemma":[0.9993774,0.0000569605,0.0002140234,0.00025696677,0.00008209679,0.000012500328],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00012633894,0.00014172454,0.00031118927,0.00006789512,0.000048960752,0.0000020872974,0.00031801735,0.00014878745,0.0011700195],"category_scores_gemma":[0.00001959796,0.00010492007,0.00016201996,0.00019459706,0.00043658144,0.000035621455,0.00015619704,0.00018908331,0.000030595416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001932707,0.00044560753,0.0002967607,0.000029617215,0.00018484607,0.0000056591234,0.000088856796,0.000026349506,0.9878504,0.001837528,0.008695436,0.00034565348],"study_design_scores_gemma":[0.0020035945,0.000103189086,0.0009262864,0.00001022933,0.00009803188,0.000028175064,0.000032482196,0.0000091217025,0.8063113,0.00001742352,0.19036646,0.00009370942],"about_ca_topic_score_codex":0.00012220352,"about_ca_topic_score_gemma":0.000009552401,"teacher_disagreement_score":0.18167104,"about_ca_system_score_codex":0.000025798368,"about_ca_system_score_gemma":0.00006346058,"threshold_uncertainty_score":0.99974304},"labels":[],"label_agreement":null},{"id":"W1855293480","doi":"10.1124/mol.106.023994","title":"Specific Rescue of Cystic Fibrosis Transmembrane Conductance Regulator Processing Mutants Using Pharmacological Chaperones","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"Cystic Fibrosis Foundation","keywords":"Cystic fibrosis transmembrane conductance regulator; Potentiator; ΔF508; Mutant; Cystic fibrosis; Mutant protein; Chemistry; Cell biology; Biochemistry; Biology; Pharmacology; Gene; Genetics","score_opus":0.025889148227841493,"score_gpt":0.3385634827465348,"score_spread":0.3126743345186933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1855293480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9814529,0.008444041,0.007809365,0.00050350564,0.00027201057,0.0009126696,0.00004133939,0.00009866399,0.00046552627],"genre_scores_gemma":[0.9808041,0.00009752677,0.018325912,0.00021581598,0.0003153307,0.00005168782,0.000030374324,0.000059121336,0.000100124176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997174,0.0002320764,0.00065253366,0.00062333146,0.00058240525,0.00073564914],"domain_scores_gemma":[0.9989848,0.00013025504,0.00016431719,0.00021829753,0.00028151178,0.00022080781],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002783433,0.00032042098,0.00073953124,0.00019747987,0.00012656281,0.000018670737,0.00024366361,0.0001662448,0.00081568747],"category_scores_gemma":[0.000050779454,0.00029139133,0.00017046978,0.00063853705,0.0006794738,0.00014629611,0.00006870843,0.00037138278,0.000015324234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015645635,0.00034904422,0.00021909892,0.00044868578,0.000090047695,0.00095800724,0.000036892267,0.0019387525,0.9919942,0.0000710325,0.0003544263,0.00197525],"study_design_scores_gemma":[0.004131004,0.0004309939,0.0024240375,0.00014322554,0.00032551025,0.00045627163,0.000027075368,0.008619701,0.97978026,0.00014898274,0.0032451958,0.00026775498],"about_ca_topic_score_codex":0.000024399422,"about_ca_topic_score_gemma":0.0000013444998,"teacher_disagreement_score":0.012213951,"about_ca_system_score_codex":0.00016536517,"about_ca_system_score_gemma":0.00022903328,"threshold_uncertainty_score":0.9999538},"labels":[],"label_agreement":null},{"id":"W1865262906","doi":"10.1124/mol.60.1.200","title":"Fast and Slow Gating of CLC-1: Differential Effects of 2-(4-Chlorophenoxy) Propionic Acid and Dominant Negative Mutations","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"","keywords":"Gating; Biophysics; Chemistry; Chloride channel; Myotonia; Sodium channel; Mutant; Mutation; Stereochemistry; Biochemistry; Sodium; Genetics; Biology","score_opus":0.005303255623845962,"score_gpt":0.2488083743073116,"score_spread":0.24350511868346564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1865262906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9782494,0.0004329358,0.020482047,0.000080796046,0.00031663827,0.00030380004,0.000005483353,0.0000049504297,0.00012400163],"genre_scores_gemma":[0.9991278,0.00015325136,0.000371719,0.00007465601,0.00010271363,0.00003293956,0.000038227754,0.000013190779,0.000085470965],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992613,0.00010458621,0.000197675,0.0002213933,0.000076416945,0.00013861901],"domain_scores_gemma":[0.99959874,0.0000312112,0.00013581532,0.00008065268,0.00009840233,0.000055147186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004778043,0.000116967574,0.00016976928,0.00006511899,0.000057619978,0.0000048203497,0.0000464445,0.00009932408,0.000020979794],"category_scores_gemma":[0.000066983564,0.00010967842,0.000045603272,0.000082045255,0.00018997354,0.0000047224516,0.0000721482,0.0000616765,4.5219844e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017575914,0.00007213504,0.00046897092,0.000085754735,0.00007027998,0.000007832385,0.00015513982,0.000117954776,0.9962188,0.000072911615,0.000058737576,0.0024956956],"study_design_scores_gemma":[0.0018733236,0.00042716513,0.0028889768,0.00001315139,0.00007339519,0.000029491515,0.00006355882,0.0014102604,0.99287885,0.000087424516,0.00015440154,0.00009997139],"about_ca_topic_score_codex":0.0000065943245,"about_ca_topic_score_gemma":0.0000013383702,"teacher_disagreement_score":0.020878484,"about_ca_system_score_codex":0.0000066967655,"about_ca_system_score_gemma":0.000027099866,"threshold_uncertainty_score":0.4472556},"labels":[],"label_agreement":null},{"id":"W1907315130","doi":"10.1124/mol.115.099747","title":"Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences","keywords":"Enantiomer; Phosphodiesterase; Stereochemistry; Chemistry; Dimer; Bioavailability; Asymmetry; Enzyme; Biochemistry; Pharmacology; Biology; Organic chemistry; Physics","score_opus":0.015515471936875835,"score_gpt":0.2873800180636946,"score_spread":0.27186454612681876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1907315130","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935315,0.0011936497,0.0041292156,0.00010709871,0.00044681836,0.00041986958,0.00004769252,0.000008563622,0.0001155437],"genre_scores_gemma":[0.99788475,0.0000387422,0.0014731355,0.0002853301,0.00006910783,0.00004115689,0.000104390114,0.000020082887,0.00008327707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907434,0.00010667187,0.00026667706,0.0002647621,0.000097449934,0.00019008665],"domain_scores_gemma":[0.99931055,0.000020385298,0.00019889855,0.00010926298,0.00026266224,0.00009826119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001799606,0.00015028797,0.00023841426,0.00011157075,0.000038633032,0.0000053021877,0.00007630196,0.00013640073,0.0000042446823],"category_scores_gemma":[0.000061049075,0.00013936793,0.00008575686,0.00015703267,0.0001402915,0.000006588526,0.000081236794,0.00006195358,3.802656e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066443376,0.00004802146,0.001072996,0.00005655805,0.00016616443,0.0000031643046,0.000121306606,0.00012906229,0.9940372,0.00006846341,0.0016920196,0.001940593],"study_design_scores_gemma":[0.0021631727,0.0008418961,0.0008567875,0.00001060696,0.00007958088,0.000034580276,0.00009711416,0.00045389225,0.993329,0.00011064555,0.0018786594,0.000144105],"about_ca_topic_score_codex":0.00001552652,"about_ca_topic_score_gemma":0.000002414525,"teacher_disagreement_score":0.004353229,"about_ca_system_score_codex":0.000024921173,"about_ca_system_score_gemma":0.00011067939,"threshold_uncertainty_score":0.5683259},"labels":[],"label_agreement":null},{"id":"W1908136873","doi":"10.1124/mol.59.5.1029","title":"Expression of Multiple Subtypes of Muscarinic Receptors and Cellular Distribution in the Human Heart","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute","funders":"","keywords":"Muscarinic acetylcholine receptor; Gene isoform; Immunostaining; Receptor; Molecular biology; Acetylcholine receptor; Biology; Reverse transcription polymerase chain reaction; Antibody; Confocal microscopy; Messenger RNA; Immunofluorescence; Immunohistochemistry; Cell biology; Gene; Biochemistry; Genetics; Immunology","score_opus":0.011127985554724752,"score_gpt":0.27084216071877154,"score_spread":0.25971417516404677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1908136873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99661106,0.00091043685,0.0020364672,0.00007390801,0.00011073989,0.00018702209,0.0000070863525,0.0000029205921,0.000060373113],"genre_scores_gemma":[0.9994468,0.000114864015,0.00013805044,0.00010399291,0.000042945314,0.000017377077,0.00010989911,0.0000095616515,0.00001648929],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991101,0.00021937599,0.0002264201,0.00019987134,0.0000915191,0.00015272491],"domain_scores_gemma":[0.99967796,0.000020440224,0.00009002467,0.00014273215,0.000039622944,0.000029204182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030310426,0.00009743114,0.00015373954,0.000033947093,0.000038935166,0.0000035007033,0.00013603595,0.00011423304,0.00008371064],"category_scores_gemma":[0.000023626211,0.00007969431,0.00006405712,0.0000912908,0.00008388947,0.0000027352528,0.00006904254,0.000085261345,5.314897e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053776403,0.00008494252,0.005363795,0.000015847008,0.000012057511,0.000005343546,0.0000675641,0.00008646101,0.9937603,0.000058851678,0.0003133722,0.00017773107],"study_design_scores_gemma":[0.000655023,0.0002124641,0.0012570567,0.000009513098,0.000017927694,0.00000739864,0.000091204914,0.000058496174,0.9913563,0.00006949563,0.006188193,0.00007693432],"about_ca_topic_score_codex":0.000037185644,"about_ca_topic_score_gemma":0.0000050728604,"teacher_disagreement_score":0.0058748205,"about_ca_system_score_codex":0.0000056279328,"about_ca_system_score_gemma":0.000015067348,"threshold_uncertainty_score":0.32498398},"labels":[],"label_agreement":null},{"id":"W1936140600","doi":"10.1124/mol.59.1.144","title":"γ-Aminobutyric Acid Type B Receptors with Specific Heterodimer Composition and Postsynaptic Actions in Hippocampal Neurons Are Targets of Anticonvulsant Gabapentin Action","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":143,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Merck Canada Inc. (Canada); Montreal Heart Institute","funders":"","keywords":"Postsynaptic potential; Gabapentin; Anticonvulsant; Chemistry; Receptor; Pharmacology; Hippocampal formation; Neuroscience; Action (physics); Biochemistry; Biology; Epilepsy; Medicine","score_opus":0.06614223744666624,"score_gpt":0.3485665522664789,"score_spread":0.28242431481981267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1936140600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972728,0.00012778441,0.000112365415,0.00087988074,0.0009426071,0.0005305473,0.0000057158168,0.000046512498,0.00008177305],"genre_scores_gemma":[0.9975853,0.0012378915,0.000022566992,0.0009961005,0.00003648656,0.00003319266,0.0000025337924,0.000031537347,0.000054375017],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99745774,0.00078238436,0.00029760215,0.00061447115,0.000291709,0.0005561026],"domain_scores_gemma":[0.9992478,0.00017122779,0.00017300708,0.000181947,0.000070105845,0.0001558946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015642836,0.0002269899,0.00029802148,0.00040082133,0.00018477796,0.000028726821,0.00026492338,0.000084373365,0.00027732147],"category_scores_gemma":[0.0000450329,0.00021566471,0.00004647826,0.0010528169,0.0005867803,0.00024405478,0.0001225486,0.0005382846,0.0000485318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006282536,0.00042212682,0.007427318,0.0000191747,0.000008701935,0.001207652,0.000055577988,0.00016407426,0.9895198,0.000026098463,0.00013940276,0.0003818187],"study_design_scores_gemma":[0.0013674053,0.00066163356,0.010493197,0.000011179813,0.000035062476,0.0007598703,0.000034340574,0.000638927,0.98494416,0.000013154123,0.0008562552,0.00018481737],"about_ca_topic_score_codex":0.0000062765525,"about_ca_topic_score_gemma":0.0000029455057,"teacher_disagreement_score":0.0045756423,"about_ca_system_score_codex":0.000048577298,"about_ca_system_score_gemma":0.00005277581,"threshold_uncertainty_score":0.87945515},"labels":[],"label_agreement":null},{"id":"W1963422225","doi":"10.1124/mol.60.6.1243","title":"Agonist-Stimulated and Tonic Internalization of Metabotropic Glutamate Receptor 1a in Human Embryonic Kidney 293 Cells: Agonist-Stimulated Endocytosis Is β-Arrestin1 Isoform-Specific","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"G protein-coupled receptor; Metabotropic glutamate receptor; Cell biology; Internalization; Biology; Metabotropic receptor; HEK 293 cells; Metabotropic glutamate receptor 7; Receptor; Chemistry; Agonist; Biochemistry; Signal transduction","score_opus":0.011441244714994686,"score_gpt":0.2739181877877286,"score_spread":0.2624769430727339,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963422225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98495173,0.003236394,0.009950853,0.0002311546,0.0008316253,0.0005545811,0.000054617474,0.00003927108,0.00014979736],"genre_scores_gemma":[0.995366,0.0019587923,0.000776059,0.0009660642,0.00013383484,0.000051703784,0.00031399916,0.00008064347,0.0003529318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973406,0.00031042413,0.0007148763,0.0007865187,0.00022193402,0.0006256232],"domain_scores_gemma":[0.9988598,0.000022429082,0.00032883318,0.00036240052,0.00017669624,0.00024980988],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027770104,0.00043350522,0.0005504472,0.00024768902,0.00014549877,0.00004909242,0.00037472244,0.0003634309,0.0015651317],"category_scores_gemma":[0.000027814565,0.00045935655,0.00019468219,0.00034477413,0.00017281681,0.000017999539,0.00023609654,0.00028032056,0.000021607299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040385625,0.00018953126,0.00042567067,0.000065895445,0.00021705758,0.000074024145,0.00009544003,0.0022902424,0.99392825,0.00013368374,0.0014333205,0.000743034],"study_design_scores_gemma":[0.0029721963,0.00065077085,0.000085386084,0.000050541323,0.00011911251,0.000027415263,0.000021153963,0.003575292,0.9496588,0.00012359995,0.04230094,0.00041474984],"about_ca_topic_score_codex":0.000085314954,"about_ca_topic_score_gemma":0.000007224133,"teacher_disagreement_score":0.0442694,"about_ca_system_score_codex":0.000074954325,"about_ca_system_score_gemma":0.000116874086,"threshold_uncertainty_score":0.99978584},"labels":[],"label_agreement":null},{"id":"W1966430777","doi":"10.1124/mol.105.013953","title":"The Impact of Blunted β-Adrenergic Responsiveness on Growth Regulatory Pathways in Hypertension","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Adrenergic; Adrenergic receptor; Internal medicine; Medicine; Endocrinology; Receptor","score_opus":0.020863717428185945,"score_gpt":0.309615410352646,"score_spread":0.28875169292446007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966430777","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955805,0.0008818103,0.000019635107,0.0022711703,0.00009388887,0.0002956429,0.0000023296122,0.00002543572,0.0008296131],"genre_scores_gemma":[0.9980998,0.00014584987,0.000054431213,0.001469487,0.000074486736,0.00001482912,0.000010592694,0.000023677361,0.000106819614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987126,0.00024768506,0.00030884627,0.00022222634,0.00024879747,0.0002598505],"domain_scores_gemma":[0.9991764,0.0001603592,0.000090733556,0.0002202491,0.00023623534,0.00011606159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003326765,0.00015346591,0.0003207522,0.00022932471,0.000064815686,0.000003847317,0.00009463694,0.00012244353,0.000088191795],"category_scores_gemma":[0.000116572024,0.00009790749,0.00017588571,0.0002797942,0.000121592646,0.000029009383,0.000037906175,0.00020758966,0.000024865418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002681221,0.00027599136,0.0007823106,0.000006514128,0.0000745573,0.0004501206,0.000043652282,0.0014672133,0.9856773,0.0008869919,0.001267173,0.00638696],"study_design_scores_gemma":[0.004480359,0.0008786542,0.32175478,0.00004862198,0.000083374085,0.00027074342,0.000022717653,0.011364402,0.65834594,0.00015066499,0.0024595356,0.00014018711],"about_ca_topic_score_codex":0.000036268193,"about_ca_topic_score_gemma":0.0000044579183,"teacher_disagreement_score":0.32733133,"about_ca_system_score_codex":0.00017483016,"about_ca_system_score_gemma":0.00021399141,"threshold_uncertainty_score":0.39925516},"labels":[],"label_agreement":null},{"id":"W1970081438","doi":"10.1124/mol.112.078352","title":"Carbonylation Induces Heterogeneity in Cardiac Ryanodine Receptor Function in Diabetes Mellitus","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; University of Calgary","keywords":"Ryanodine receptor; Internal medicine; Endocrinology; Chemistry; Ryanodine receptor 2; Endoplasmic reticulum; Methylglyoxal; Myocyte; Biochemistry; Biology; Medicine","score_opus":0.0163623254863862,"score_gpt":0.31598021052553793,"score_spread":0.2996178850391517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970081438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98986226,0.0080561545,0.0003536595,0.00029053577,0.0007484198,0.00037269513,0.000008962663,0.000012739114,0.00029457366],"genre_scores_gemma":[0.998109,0.00046317172,0.0002727398,0.00035380907,0.00034518325,0.0001516134,0.00021881536,0.000027089245,0.0000586027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982684,0.0004694899,0.00024147383,0.00036668798,0.00013989012,0.000514027],"domain_scores_gemma":[0.99953437,0.000019289928,0.00006375034,0.00021511751,0.000064510146,0.00010298078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005491204,0.00015675274,0.00018541874,0.00017543959,0.00003118977,0.0000070983447,0.00012987117,0.00017586871,0.000063486375],"category_scores_gemma":[0.000088471446,0.00017365509,0.00005548097,0.00031403496,0.00006225385,0.000017431134,0.00010455603,0.00020381613,0.000028951865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089200235,0.00011816159,0.036408905,0.000016474238,0.000037311846,0.0000013120813,0.00003643206,0.0006026708,0.9583465,0.000030450878,0.0002462817,0.0040663257],"study_design_scores_gemma":[0.00058873836,0.00010272183,0.02039288,0.0000033847657,0.000010376122,7.207821e-7,0.000014576041,0.00004300455,0.945988,0.00003175234,0.032655023,0.00016880127],"about_ca_topic_score_codex":0.000017520559,"about_ca_topic_score_gemma":0.000009760381,"teacher_disagreement_score":0.03240874,"about_ca_system_score_codex":0.000076728305,"about_ca_system_score_gemma":0.000051370247,"threshold_uncertainty_score":0.7081449},"labels":[],"label_agreement":null},{"id":"W1970115513","doi":"10.1124/mol.107.036285","title":"Alternative Translation Initiation of Human Regulators of G-Protein Signaling-2 Yields a Set of Functionally Distinct Proteins","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"U.S. National Library of Medicine; National Institute of General Medical Sciences","keywords":"RGS2; Regulator of G protein signaling; Adenylyl cyclase; Biology; Eukaryotic translation; Translation (biology); G protein; Cell biology; ORFS; Signal transduction; Genetics; Open reading frame; Molecular biology; Messenger RNA; Peptide sequence; Gene; GTPase-activating protein","score_opus":0.02253574376935666,"score_gpt":0.3045212521825322,"score_spread":0.2819855084131755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970115513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8747288,0.00043863006,0.12379903,0.00003339826,0.00006368271,0.00055398187,0.00003902572,0.000008018768,0.00033541417],"genre_scores_gemma":[0.99789524,0.0000041447834,0.0016361172,0.0000448937,0.000114031405,0.00003099293,0.00022504291,0.000021874397,0.000027646553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985337,0.00015464044,0.0006094231,0.00026480542,0.00025224377,0.00018516608],"domain_scores_gemma":[0.99891436,0.000019833427,0.00052266027,0.00016062649,0.00032226313,0.000060233102],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058272004,0.0001492519,0.00024967844,0.00014953758,0.000046008547,0.0000031368304,0.00014110458,0.00018878083,0.00012508649],"category_scores_gemma":[0.00004547315,0.00017243331,0.00015873233,0.00019642862,0.00018003119,0.00000742887,0.000041879382,0.000097130716,5.455278e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034075338,0.00011536709,0.00030632864,0.000112542715,0.00014633973,0.000008703273,0.00008718603,0.0011878255,0.99531853,0.0007267929,0.000012838892,0.0016367871],"study_design_scores_gemma":[0.0012627196,0.00057817873,0.0010097574,0.00004718127,0.000067804736,0.0000058456108,0.000023773857,0.00023594222,0.9956217,0.000738969,0.00026471182,0.00014341177],"about_ca_topic_score_codex":0.000070434864,"about_ca_topic_score_gemma":0.000028324459,"teacher_disagreement_score":0.12316644,"about_ca_system_score_codex":0.000017008997,"about_ca_system_score_gemma":0.000084465784,"threshold_uncertainty_score":0.7031626},"labels":[],"label_agreement":null},{"id":"W1971462812","doi":"10.1124/mol.107.034769","title":"Regulation of D1 Dopamine Receptor Trafficking and Signaling by Caveolin-1","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"Dopamine receptor D1; Dopamine receptor; Cell biology; Dopamine; Caveolin 1; Chemistry; Receptor; Dopamine receptor D2; Biology; Neuroscience; Biochemistry","score_opus":0.004926575143849208,"score_gpt":0.2516955198628489,"score_spread":0.24676894471899968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971462812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853441,0.0042494843,0.009623852,0.000084104635,0.00018329514,0.00016458784,0.000007714487,0.000009233865,0.000333626],"genre_scores_gemma":[0.9986026,0.00018700116,0.0004927118,0.00026349054,0.00014593646,0.000007601408,0.0001121021,0.000023163262,0.00016537374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894893,0.000053746735,0.00030965937,0.00031406,0.00010071418,0.00027287574],"domain_scores_gemma":[0.9996142,0.000022173366,0.000111094734,0.00010814266,0.000071305636,0.00007312268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004072268,0.00014218215,0.00017703748,0.00009091596,0.00003147373,0.000005781075,0.00010206723,0.00016351197,0.000053339303],"category_scores_gemma":[0.000028077142,0.000158027,0.000049454135,0.000136169,0.0001041577,0.000003897745,0.000059405338,0.00009965433,0.0000016988839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016116443,0.000078098514,0.00061342446,0.00004460835,0.00003421201,0.000013154838,0.000052027564,0.00020068916,0.9952421,0.000032157954,0.00049727125,0.0030310643],"study_design_scores_gemma":[0.0010373933,0.00014905965,0.00029019956,0.000009549516,0.000026766777,0.000020438843,0.000049720456,0.00008908188,0.98725575,0.000021687763,0.010892993,0.00015736987],"about_ca_topic_score_codex":0.00001491896,"about_ca_topic_score_gemma":0.0000117579875,"teacher_disagreement_score":0.013258517,"about_ca_system_score_codex":0.000013780715,"about_ca_system_score_gemma":0.000035322068,"threshold_uncertainty_score":0.64441544},"labels":[],"label_agreement":null},{"id":"W1975881580","doi":"10.1124/mol.63.1.136","title":"Activation of Microsomal Glutathione S-Transferase by Peroxynitrite","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Tetranitromethane; Peroxynitrite; Chemistry; Biochemistry; Microsome; Glutathione; Enzyme; Dithiothreitol; Tyrosine; Lipid peroxidation; Enzyme assay; Nitration; Superoxide","score_opus":0.004885039762210564,"score_gpt":0.24275774792667013,"score_spread":0.23787270816445957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975881580","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97165114,0.0015765901,0.025247425,0.00024017048,0.00020907914,0.00026750335,0.00005407271,0.0000144838305,0.00073955336],"genre_scores_gemma":[0.997448,0.00021030192,0.00041557057,0.0014000525,0.000044066142,0.000034698438,0.00017859433,0.000035625242,0.00023306279],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986988,0.0002084822,0.00029346615,0.00035242861,0.00012925573,0.00031759162],"domain_scores_gemma":[0.99952894,0.000015060817,0.00005978041,0.00019539254,0.000088900444,0.00011190328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014761137,0.00020790202,0.00021177912,0.00006124529,0.000068230496,0.0000078140465,0.00014969238,0.00019321011,0.00025111102],"category_scores_gemma":[0.00001651392,0.00022415287,0.00015283564,0.00013570537,0.00012505335,0.0000054111592,0.000018431243,0.00013776144,0.000009371823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024821158,0.00022254651,0.0001395308,0.000020386564,0.000115234165,0.000012959082,0.00004634935,0.00009582936,0.9953076,0.00041566291,0.003073948,0.00030172654],"study_design_scores_gemma":[0.0032730633,0.00034155409,0.000043359774,0.0000048406696,0.00006458377,0.000038403865,0.00002338678,0.000014501728,0.96711665,0.00004770975,0.02881533,0.00021660818],"about_ca_topic_score_codex":0.000026062598,"about_ca_topic_score_gemma":0.0000019602053,"teacher_disagreement_score":0.028190956,"about_ca_system_score_codex":0.000011584335,"about_ca_system_score_gemma":0.000086184366,"threshold_uncertainty_score":0.9140689},"labels":[],"label_agreement":null},{"id":"W1979468645","doi":"10.1124/mol.63.1.96","title":"Down-Regulation of Hepatic Nicotine Metabolism and a CYP2A6-Like Enzyme in African Green Monkeys after Long-Term Nicotine Administration","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Nicotine; CYP2A6; Cotinine; Phenobarbital; Endocrinology; CYP2B6; Chemistry; Internal medicine; Metabolism; Pharmacology; Saline; Medicine; Cytochrome P450; CYP1A2","score_opus":0.006313088449191309,"score_gpt":0.26658436092926246,"score_spread":0.26027127248007115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979468645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943941,0.0026186015,0.0015560413,0.00019767102,0.00027074496,0.00065685634,0.000017389257,0.000014960199,0.00027360968],"genre_scores_gemma":[0.9981657,0.00019650724,0.0006830745,0.0003310578,0.00010272861,0.00014047221,0.00010048492,0.000046250403,0.00023369146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99770844,0.0004937887,0.0005928267,0.00059557654,0.00019715035,0.00041223245],"domain_scores_gemma":[0.99914,0.000027831129,0.00024990726,0.00033081727,0.000115250215,0.00013615312],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033052464,0.00031655538,0.00042787223,0.0001611447,0.00003700349,0.000011801917,0.00018075257,0.0002352387,0.00019173272],"category_scores_gemma":[0.00006561838,0.00033141338,0.00011589541,0.00026682822,0.00016912879,0.000012144572,0.00013746077,0.00019106634,0.000006725999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003194426,0.00037963784,0.030664967,0.000056837678,0.00013792323,0.0000068978416,0.000092303126,0.00005225701,0.9674766,0.00007840026,0.00008851957,0.00064621744],"study_design_scores_gemma":[0.0028293263,0.00038670393,0.031777952,0.000012272515,0.00017518854,0.00004326508,0.000019410194,0.00012419542,0.9625756,0.00004294543,0.0017020352,0.0003110893],"about_ca_topic_score_codex":0.000046621582,"about_ca_topic_score_gemma":0.00017182918,"teacher_disagreement_score":0.0049009807,"about_ca_system_score_codex":0.00002944967,"about_ca_system_score_gemma":0.00012857489,"threshold_uncertainty_score":0.9999138},"labels":[],"label_agreement":null},{"id":"W1979842096","doi":"10.1124/mol.61.4.905","title":"The Batrachotoxin Receptor on the Voltage-Gated Sodium Channel is Guarded by the Channel Activation Gate","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Batrachotoxin; Sodium channel; Biophysics; Chemistry; Mutant; Electrophorus; Xenopus; Ligand-gated ion channel; Ion channel; Receptor; Stereochemistry; Biochemistry; Acetylcholine receptor; Sodium; Biology; Torpedo","score_opus":0.016356171620469675,"score_gpt":0.24798263181691002,"score_spread":0.23162646019644034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979842096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8323769,0.0018562761,0.01477145,0.13651091,0.006238647,0.0027708625,0.00010801574,0.00013900865,0.005227963],"genre_scores_gemma":[0.97219145,0.0004097455,0.000004386423,0.01850863,0.00075858104,0.00021669384,0.00015264862,0.00004621594,0.0077116312],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982206,0.0003942527,0.00026742095,0.00043075831,0.00025378264,0.00043316948],"domain_scores_gemma":[0.9990673,0.00010840171,0.00017697278,0.00041786127,0.00015154241,0.000077932775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043694876,0.0002666126,0.00013195492,0.000040136867,0.00072546,0.00006307421,0.0004284904,0.00023159248,0.00052644144],"category_scores_gemma":[0.00011061014,0.00015262025,0.00015707966,0.00021597707,0.00021963545,0.000007327548,0.00009094217,0.00031658058,0.00017911632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014006117,0.000066882996,0.0000011673258,0.000002511535,0.000099540004,9.836468e-7,0.00012562687,0.00034790052,0.6382502,0.0000698057,0.35996047,0.0009348851],"study_design_scores_gemma":[0.0005804579,0.00015962821,0.000012780116,0.0000025597533,0.000022436318,0.000005691779,0.00009636661,0.011352195,0.6526933,0.000067329456,0.33486775,0.0001395632],"about_ca_topic_score_codex":0.000010406028,"about_ca_topic_score_gemma":0.0000014258237,"teacher_disagreement_score":0.1398146,"about_ca_system_score_codex":0.000037799688,"about_ca_system_score_gemma":0.00002137343,"threshold_uncertainty_score":0.6223673},"labels":[],"label_agreement":null},{"id":"W1984108641","doi":"10.1124/mol.65.3.646","title":"Selective Knock-Down of P2X7 ATP Receptor Function by Dominant-Negative Subunits","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Receptor; Function (biology); Cell biology; Chemistry; Biology; Biophysics; Genetics","score_opus":0.005485618150578483,"score_gpt":0.2511765570477469,"score_spread":0.2456909388971684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984108641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781704,0.0033411658,0.0164441,0.00038206365,0.00040867165,0.0003309601,0.000043664582,0.0000179609,0.0008610099],"genre_scores_gemma":[0.99734056,0.00016104484,0.0004947449,0.0011048111,0.00021430376,0.000057369183,0.00016780135,0.000038073835,0.00042126214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867797,0.00014728309,0.0002815631,0.00042131412,0.00013686037,0.00033498704],"domain_scores_gemma":[0.9993063,0.00002333306,0.00017287202,0.00017272156,0.0002239313,0.00010083141],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013248927,0.00022870817,0.0002462748,0.000074981064,0.00008307717,0.0000063323414,0.00019065727,0.00022385184,0.00016904353],"category_scores_gemma":[0.000051856237,0.00023416674,0.00012375525,0.0002390566,0.00014261952,0.000006537724,0.000098003846,0.00017748913,0.000027469352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042399313,0.00016412202,0.00009975701,0.000017646707,0.000257923,0.000009982535,0.00011930054,0.00076755363,0.948195,0.00008064426,0.049699277,0.00016479453],"study_design_scores_gemma":[0.002517917,0.0007680313,0.000087947046,0.000010135572,0.0001064872,0.000016262302,0.00005885792,0.000011560184,0.9674433,0.00019916738,0.02854381,0.00023653699],"about_ca_topic_score_codex":0.000068206515,"about_ca_topic_score_gemma":0.0000018523111,"teacher_disagreement_score":0.021155467,"about_ca_system_score_codex":0.000041674033,"about_ca_system_score_gemma":0.00014712926,"threshold_uncertainty_score":0.9549043},"labels":[],"label_agreement":null},{"id":"W1984705614","doi":"10.1124/mol.105.021931","title":"Tamoxifen and Raloxifene Differ in Their Functional Interactions with Aspartate 351 of Estrogen Receptor α","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"","keywords":"Raloxifene; Tamoxifen; Chemistry; Estrogen receptor; Selective estrogen receptor modulator; Antiestrogen; Stereochemistry; Side chain; Estrogen; Tertiary amine; Agonist; Antagonist; Pharmacology; Receptor; Biochemistry; Internal medicine; Endocrinology; Biology; Medicine; Organic chemistry; Breast cancer","score_opus":0.003808025171247728,"score_gpt":0.2194979069808477,"score_spread":0.21568988180959997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984705614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964871,0.001493599,0.00069577654,0.0002473184,0.00019216744,0.00022402586,0.000015898244,0.000010491678,0.0006336512],"genre_scores_gemma":[0.99880207,0.00009781885,0.00032193793,0.00018435913,0.00011364464,0.000054901004,0.00017334537,0.00002477113,0.0002271831],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990967,0.00012384818,0.00019406555,0.00028767248,0.00007101403,0.00022670024],"domain_scores_gemma":[0.99967533,0.000019056357,0.00008081402,0.00011869745,0.00004763385,0.00005844923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007993225,0.00016681688,0.00017964789,0.00008375402,0.00003629415,0.000006287659,0.000075410855,0.000119607714,0.000052636948],"category_scores_gemma":[0.0000053921603,0.00013653668,0.00005870529,0.000113082766,0.00014026291,0.0000050448593,0.000059040667,0.00015797245,0.000005013575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041614054,0.00016175494,0.004915255,0.000011825875,0.00013654998,0.000025596626,0.000016292865,0.0006238892,0.99156624,0.000091976144,0.0017227421,0.00031174155],"study_design_scores_gemma":[0.0017119995,0.00033845476,0.0044480213,0.0000092437285,0.00004898454,0.00007442487,0.000010040562,0.00014458079,0.9886007,0.00006308997,0.004397923,0.00015256152],"about_ca_topic_score_codex":0.000033250184,"about_ca_topic_score_gemma":0.00000896516,"teacher_disagreement_score":0.00296556,"about_ca_system_score_codex":0.000013871313,"about_ca_system_score_gemma":0.00004598871,"threshold_uncertainty_score":0.5567804},"labels":[],"label_agreement":null},{"id":"W1985018383","doi":"10.1124/mol.105.015586","title":"Alkylation of β-Tubulin on Glu 198 by a Microtubule Disrupter","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"","keywords":"Tubulin; Chemistry; Cysteine; Alkylation; Isoelectric point; Peptide; Iodoacetamide; Microtubule; Trypsin; Gel electrophoresis; Stereochemistry; Biochemistry; Biology; Enzyme","score_opus":0.0042924553555008195,"score_gpt":0.2612086618545163,"score_spread":0.2569162064990155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985018383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905338,0.0013996146,0.0050338213,0.00077775976,0.0001927726,0.00032314667,0.00006965873,0.000015903617,0.0016534966],"genre_scores_gemma":[0.9936039,0.00023875471,0.00084605435,0.00393016,0.00021328001,0.000044096407,0.00031953197,0.000039487175,0.00076476677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877226,0.0001060769,0.00029875824,0.0004007636,0.000114442046,0.00030767216],"domain_scores_gemma":[0.99943084,0.0000110584715,0.0001245942,0.00027436326,0.00007034463,0.00008880585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010863921,0.0002090772,0.00020154795,0.00006671105,0.000044598415,0.000008094847,0.0002312737,0.00021500744,0.00019620234],"category_scores_gemma":[0.00001370323,0.0002173908,0.0001408503,0.00008199223,0.00009467611,0.000004095488,0.0000972815,0.00013318873,0.000065227825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016351174,0.0002586928,0.0001284794,0.00001495382,0.000103816245,0.000005473518,0.000026984872,0.00038958128,0.9643876,0.000074102485,0.03038816,0.0040586684],"study_design_scores_gemma":[0.00097365107,0.00029146488,0.000051970354,0.0000048747706,0.00004258359,0.000011899627,0.000005118898,0.0002705904,0.7828738,0.000012202881,0.21529102,0.00017079948],"about_ca_topic_score_codex":0.000009846998,"about_ca_topic_score_gemma":0.000007820783,"teacher_disagreement_score":0.18490286,"about_ca_system_score_codex":0.00002597017,"about_ca_system_score_gemma":0.000034634613,"threshold_uncertainty_score":0.8864939},"labels":[],"label_agreement":null},{"id":"W1985342123","doi":"10.1124/mol.65.4.925","title":"Interactions of Nucleoside Analogs, Caffeine, and Nicotine with Human Concentrative Nucleoside Transporters 1 and 2 Stably Produced in a Transport-Defective Human Cell Line","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"Uridine; Nucleoside; Nucleoside transporter; Affinities; Adenosine; Stereochemistry; Deoxyuridine; Caffeine; Chemistry; Transporter; Biochemistry; Biology; DNA; RNA","score_opus":0.0063911532869308976,"score_gpt":0.2647368811201475,"score_spread":0.2583457278332166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985342123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960928,0.0011518619,0.0017799916,0.00020843292,0.00003383321,0.00044770312,0.000031219242,0.000012249261,0.00024191465],"genre_scores_gemma":[0.99906504,0.000084140636,0.0002996262,0.00027809633,0.000053111202,0.00003501356,0.00012213596,0.00003407943,0.000028740786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987139,0.00011401176,0.00032561924,0.00048351052,0.00008588282,0.00027704373],"domain_scores_gemma":[0.9995244,0.000010974331,0.00014486974,0.00013476962,0.00008043587,0.00010456566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000131589,0.00023825387,0.00031357096,0.00010799109,0.00007788155,0.0000061604906,0.000092701004,0.00009758323,0.00002832163],"category_scores_gemma":[0.0000036521812,0.00022913788,0.00005362225,0.0001482105,0.00024755948,0.000012033277,0.000024774214,0.00020465159,2.440131e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019066245,0.0002819398,0.007845268,0.00005845307,0.00014196451,0.0001248298,0.0006533141,0.001419399,0.9890971,0.000094513394,0.00004784681,0.000044669447],"study_design_scores_gemma":[0.00477891,0.0012101732,0.009832549,0.000037581038,0.00017325276,0.000045580175,0.00021855425,0.000014309053,0.98319846,0.000058272362,0.00018365312,0.00024868848],"about_ca_topic_score_codex":0.00034529428,"about_ca_topic_score_gemma":0.00026953997,"teacher_disagreement_score":0.0058986633,"about_ca_system_score_codex":0.00002214954,"about_ca_system_score_gemma":0.000068770634,"threshold_uncertainty_score":0.93439716},"labels":[],"label_agreement":null},{"id":"W1987749248","doi":"10.1124/mol.104.002956","title":"Molecular Basis for the Differential Agonist Affinities of Group III Metabotropic Glutamate Receptors","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Affinities; Metabotropic glutamate receptor 2; Metabotropic glutamate receptor; Metabotropic glutamate receptor 4; Agonist; Metabotropic glutamate receptor 3; Metabotropic receptor; Class C GPCR; Metabotropic glutamate receptor 5; Chemistry; Receptor; Metabotropic glutamate receptor 6; Metabotropic glutamate receptor 7; Biology; Biochemistry","score_opus":0.03596358556908827,"score_gpt":0.33004116071325706,"score_spread":0.29407757514416877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987749248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98392516,0.00025185233,0.0080413,0.002992669,0.0032215668,0.0012506209,0.000047071015,0.000088518966,0.00018120949],"genre_scores_gemma":[0.9935069,0.000444433,0.000078395344,0.0052447845,0.00011692932,0.0004374525,0.0000017495167,0.000056643505,0.00011270486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99686897,0.00055177056,0.00044960194,0.00076722575,0.0005000078,0.0008624398],"domain_scores_gemma":[0.99846995,0.0007063233,0.00020433798,0.00036402373,0.000090658395,0.00016471597],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002544842,0.00032362776,0.00042510816,0.00023417268,0.0005619926,0.000060636987,0.0012022348,0.00011157979,0.00033132712],"category_scores_gemma":[0.0002699341,0.0002519062,0.00033656321,0.00062755635,0.0014967194,0.00013992909,0.00035036646,0.00043713054,0.000029190218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041712064,0.0003205644,0.0000068576105,0.00003437562,0.000048062437,0.00026673498,0.000092398994,0.0009580003,0.990027,0.007005427,0.00023854154,0.00058490597],"study_design_scores_gemma":[0.0027502829,0.0006068542,0.000043704647,0.000005939081,0.00020720456,0.000047682694,0.000028230636,0.00041445138,0.99078846,0.0005766056,0.0043109055,0.00021970231],"about_ca_topic_score_codex":0.000020008401,"about_ca_topic_score_gemma":0.0000017657401,"teacher_disagreement_score":0.009581717,"about_ca_system_score_codex":0.000055727658,"about_ca_system_score_gemma":0.00016243888,"threshold_uncertainty_score":0.9999933},"labels":[],"label_agreement":null},{"id":"W1989180635","doi":"10.1124/mol.105.014126","title":"Vascular Smooth Muscle Cell Phenotype-Dependent Phosphodiesterase 4D Short Form Expression: Role of Differential Histone Acetylation on cAMP-Regulated Function","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Phosphodiesterase; Cell biology; Vascular smooth muscle; Adenylyl cyclase; cAMP-dependent pathway; Biology; CREB1; Signal transduction; Phosphodiesterase 3; Protein kinase A; CREB; Chemistry; Biochemistry; Endocrinology; Kinase; Gene; Enzyme; Transcription factor","score_opus":0.005189885800214232,"score_gpt":0.24099945377240758,"score_spread":0.23580956797219335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989180635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97896767,0.0013139702,0.017507788,0.00010704642,0.0008420706,0.0004951529,0.000019852949,0.000052707397,0.0006937464],"genre_scores_gemma":[0.99762785,0.00009875037,0.00033196888,0.00057070074,0.00036750353,0.00007657529,0.00047535019,0.000057619476,0.00039366432],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980776,0.00017113717,0.00045877477,0.00059368595,0.00033287198,0.00036598393],"domain_scores_gemma":[0.99905086,0.000014000414,0.00019634499,0.00042355555,0.00016515428,0.00015006373],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001549907,0.00033741916,0.00030055287,0.00012871645,0.00017614367,0.000021606838,0.00018703262,0.00033328982,0.00055133004],"category_scores_gemma":[0.0000112224225,0.00032728334,0.00023077764,0.00012446017,0.00012330747,0.000020480682,0.0001254222,0.0001896054,0.000028839275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008315569,0.00049804465,0.00009271994,0.000024464465,0.000102580576,0.0000039840374,0.000116281924,0.0069349958,0.9782013,0.00003885406,0.0010850029,0.012070192],"study_design_scores_gemma":[0.002190678,0.0005028279,0.0031372122,0.000013132186,0.00017269635,0.000002656167,0.000042630727,0.0021427511,0.9553695,0.00003901397,0.036064383,0.0003225312],"about_ca_topic_score_codex":0.000014035769,"about_ca_topic_score_gemma":0.000014334586,"teacher_disagreement_score":0.03497938,"about_ca_system_score_codex":0.000101040445,"about_ca_system_score_gemma":0.000074961165,"threshold_uncertainty_score":0.9999179},"labels":[],"label_agreement":null},{"id":"W1991105330","doi":"10.1124/mol.107.034884","title":"Desensitization of the Dopamine D1 and D2 Receptor Hetero-Oligomer Mediated Calcium Signal by Agonist Occupancy of Either Receptor","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Agonist; Desensitization (medicine); Homologous desensitization; Dopamine receptor D2; Chemistry; Receptor; Calcium; Endocrinology; Pharmacology; Internal medicine; Biophysics; Biochemistry; Biology; Medicine","score_opus":0.007364896375458016,"score_gpt":0.25985174825544877,"score_spread":0.25248685187999076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991105330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824043,0.0010905699,0.015258908,0.00016091869,0.000527616,0.00030904444,0.00007990348,0.000009007078,0.00015975296],"genre_scores_gemma":[0.99814445,0.00012381062,0.0006523409,0.0005355502,0.00014468447,0.000010537988,0.00016971887,0.0000368202,0.00018211851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985761,0.0001958095,0.00040875468,0.00032872692,0.00018618097,0.0003044245],"domain_scores_gemma":[0.9992408,0.000034958528,0.00025623047,0.00019234407,0.00017598402,0.00009968316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038322769,0.00019934052,0.00025894368,0.000058048023,0.00006743244,0.000006725587,0.00019104357,0.0002304306,0.0003528029],"category_scores_gemma":[0.00004195783,0.0001641548,0.00011294552,0.00017363662,0.00022268928,0.000004603532,0.00012608529,0.00012566274,0.00000387297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021654478,0.000087942244,0.0006005301,0.000029758143,0.00012554538,0.000002540779,0.00004455592,0.000024237896,0.9950396,0.000030243975,0.0028713637,0.00092718255],"study_design_scores_gemma":[0.00087394274,0.0002666616,0.00013623087,0.0000116758765,0.0000560323,0.000008613116,0.00003784172,0.000058371195,0.97883874,0.000010580055,0.019537563,0.00016374],"about_ca_topic_score_codex":0.000027505657,"about_ca_topic_score_gemma":0.0000031821332,"teacher_disagreement_score":0.016666198,"about_ca_system_score_codex":0.000016778795,"about_ca_system_score_gemma":0.000050538012,"threshold_uncertainty_score":0.66940385},"labels":[],"label_agreement":null},{"id":"W1998949716","doi":"10.1124/mol.105.020883","title":"Identification of Various Allosteric Interaction Sites on M1 Muscarinic Receptor Using 125I-Met35-Oxidized Muscarinic Toxin 7","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Allosteric regulation; Cooperativity; Chemistry; Stereochemistry; Ternary complex; Muscarinic acetylcholine receptor; Cooperative binding; Binding site; Dissociation constant; Ternary operation; Receptor; Biochemistry; Enzyme","score_opus":0.014191989057299558,"score_gpt":0.2945049556917786,"score_spread":0.280312966634479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998949716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877,0.0003553388,0.010084574,0.00007221244,0.0011881599,0.00037336804,0.000017638184,0.000026801048,0.00018190949],"genre_scores_gemma":[0.99752694,0.000054410502,0.0012248704,0.0003616379,0.0003036582,0.00004118578,0.00022512952,0.00005309434,0.00020906677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980114,0.0002723498,0.00062191504,0.0005678072,0.00019430512,0.00033220847],"domain_scores_gemma":[0.9990237,0.000033647764,0.00041077065,0.00031776962,0.00014509623,0.000069028174],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003442696,0.0002618593,0.0003045474,0.00017390793,0.00007872497,0.000029028222,0.00025371285,0.00025845267,0.0004914374],"category_scores_gemma":[0.00004563557,0.0002841409,0.0002300576,0.00019716047,0.000059437603,0.000010906056,0.00012470926,0.00017309458,0.000030066361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025449696,0.00023053799,0.000063557396,0.00002782392,0.00013116747,0.000009293671,0.000023093276,0.003919115,0.99408525,0.000116265604,0.0007035043,0.00043586802],"study_design_scores_gemma":[0.0011145708,0.0003881957,0.000112692374,0.000013131351,0.000119612625,0.000019781446,0.000023410965,0.0026501995,0.9915467,0.00007802216,0.0036734086,0.00026029683],"about_ca_topic_score_codex":0.000085027576,"about_ca_topic_score_gemma":0.000007513774,"teacher_disagreement_score":0.009826948,"about_ca_system_score_codex":0.00006620962,"about_ca_system_score_gemma":0.000067075496,"threshold_uncertainty_score":0.9999611},"labels":[],"label_agreement":null},{"id":"W2000067908","doi":"10.1124/mol.104.010124","title":"Intracellular cAMP and Calcium Signaling by Serotonin in Mouse Cumulus-Oocyte Complexes","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Institut de Cardiologie de Montréal","keywords":"Ionomycin; Oocyte; Intracellular; Second messenger system; Receptor; Internal medicine; Serotonin; Endocrinology; Calcium in biology; Chemistry; Cell biology; Biology; Embryo; Biochemistry; Medicine","score_opus":0.01974232787510146,"score_gpt":0.3163911821418554,"score_spread":0.29664885426675397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000067908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918356,0.0041119014,0.0006504515,0.002532235,0.00007437808,0.0006141263,0.000006379297,0.000029103529,0.000145811],"genre_scores_gemma":[0.9971182,0.000059563852,0.00057226757,0.0018667653,0.00007676856,0.000061652696,0.000024194538,0.00001570095,0.00020492982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985787,0.000256454,0.00028435313,0.0004649587,0.00007364934,0.0003418855],"domain_scores_gemma":[0.99961996,0.000040673156,0.000045555524,0.00015760682,0.00003468835,0.00010154118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040405925,0.00015733032,0.00034153395,0.00011725584,0.000031645068,0.000004005162,0.00007296298,0.00015941772,0.00021117025],"category_scores_gemma":[0.000040490024,0.00015204528,0.000037557875,0.00012619837,0.00021580815,0.000046403577,0.00005726177,0.00039351333,0.000020631709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015283166,0.00024138612,0.016314844,0.000029361214,0.000039193168,0.00022161873,0.00021988909,0.00013878783,0.97989166,0.00001646455,0.00031157513,0.0010469226],"study_design_scores_gemma":[0.0026467342,0.00013082531,0.014749975,0.00000789689,0.00003180414,0.000050241575,0.0000307789,0.0012514812,0.97420627,0.000045388577,0.0067176023,0.00013102476],"about_ca_topic_score_codex":0.000071012255,"about_ca_topic_score_gemma":0.0000123795935,"teacher_disagreement_score":0.0064060274,"about_ca_system_score_codex":0.000099901205,"about_ca_system_score_gemma":0.000040473984,"threshold_uncertainty_score":0.62002265},"labels":[],"label_agreement":null},{"id":"W2000124302","doi":"10.1124/mol.105.021246","title":"Agonist-Induced Cell Surface Trafficking of an Intracellularly Sequestered D1 Dopamine Receptor Homo-Oligomer","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Agonist; Receptor; Cell biology; 5-HT5A receptor; Cell membrane; Dopamine receptor D1; Cell; Cell surface receptor; HEK 293 cells; Endoplasmic reticulum; Biology; Chemistry; Biochemistry","score_opus":0.008453528951708353,"score_gpt":0.24897825142111968,"score_spread":0.2405247224694113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000124302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98997164,0.000993214,0.007137195,0.00009217441,0.00058673095,0.0005003372,0.000030932966,0.00004161512,0.00064615544],"genre_scores_gemma":[0.99296767,0.000039051552,0.0053629656,0.00023906812,0.000391521,0.000035713132,0.0004034524,0.00008368626,0.0004768571],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977282,0.00033626956,0.0005240442,0.0006509094,0.00021928496,0.00054125604],"domain_scores_gemma":[0.9990124,0.0000154463,0.00026591177,0.00037983473,0.00017275299,0.0001536664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034494748,0.00034644394,0.00038217823,0.00008454961,0.00010061616,0.00003647944,0.0003977879,0.00034856997,0.00053316646],"category_scores_gemma":[0.000009303184,0.00037218718,0.00018881385,0.0001737342,0.000094436386,0.000013417261,0.000113473354,0.0002198939,0.000024806248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014541538,0.00035996898,0.00003530459,0.000040062096,0.00006523545,0.000058917114,0.000035233577,0.0024628544,0.9956007,0.000068896086,0.00051970786,0.0006076876],"study_design_scores_gemma":[0.0015005799,0.00079303636,0.00001931642,0.000008979261,0.00007524441,0.000025333327,0.00004707102,0.0006326513,0.98692167,0.00003497521,0.009545252,0.00039590316],"about_ca_topic_score_codex":0.000093412804,"about_ca_topic_score_gemma":0.000011652734,"teacher_disagreement_score":0.009025544,"about_ca_system_score_codex":0.000033763743,"about_ca_system_score_gemma":0.00011557836,"threshold_uncertainty_score":0.999873},"labels":[],"label_agreement":null},{"id":"W2006226859","doi":"10.1124/mol.113.089227","title":"Dual Roles for Splice Variants of the Glucuronidation Pathway as Regulators of Cellular Metabolism","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Thioredoxin; Peroxiredoxin; Gene isoform; Biology; Alternative splicing; Superoxide dismutase; Proteomics; Cell biology; Biochemistry; Enzyme; Chemistry; Gene","score_opus":0.005287685001292188,"score_gpt":0.23855224099009673,"score_spread":0.23326455598880455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006226859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915586,0.0028908232,0.0033451617,0.00041830086,0.0005011546,0.0007216136,0.00004118771,0.0000054359703,0.0005177285],"genre_scores_gemma":[0.9979723,0.0001744606,0.0008849345,0.0003752345,0.00013610996,0.00012942703,0.00003485667,0.000025741947,0.00026693678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988194,0.0001375623,0.00033928597,0.0003064745,0.00013834846,0.00025893844],"domain_scores_gemma":[0.99908465,0.000022190243,0.00028130008,0.00032328226,0.00023790139,0.00005065697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002151459,0.00017310654,0.00029681553,0.00006218452,0.000067398716,0.00000495358,0.00026925217,0.00013544313,0.00009820861],"category_scores_gemma":[0.00009078754,0.00013668068,0.00020928666,0.00014913078,0.00015193505,0.0000052363544,0.00021626556,0.00007089656,0.0000042949955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052640382,0.00009288856,0.00006932506,0.000030946303,0.00029247857,6.744857e-7,0.000040815543,0.000059441234,0.9932811,0.004127417,0.0013857464,0.0005665211],"study_design_scores_gemma":[0.00092711474,0.00015653306,0.001722977,0.0000030972558,0.00014841509,0.000004384306,0.00004981728,0.00008886897,0.9783732,0.0010182954,0.017377982,0.00012930199],"about_ca_topic_score_codex":0.00003830047,"about_ca_topic_score_gemma":0.0000028623363,"teacher_disagreement_score":0.015992235,"about_ca_system_score_codex":0.0000075660487,"about_ca_system_score_gemma":0.00008406664,"threshold_uncertainty_score":0.5573677},"labels":[],"label_agreement":null},{"id":"W2007411895","doi":"10.1124/mol.106.030684","title":"Role of Nuclear Factor-κB and Protein Kinase C Signaling in the Expression of the Kinin B1 Receptor in Human Vascular Smooth Muscle Cells","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Molecular biology; Protein kinase C; Biology; Receptor; Signal transduction; Kinin; Endocrinology; Bradykinin; Biochemistry","score_opus":0.0074597377011758215,"score_gpt":0.24563864238592825,"score_spread":0.23817890468475242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007411895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99733365,0.0013502152,0.000011496336,0.00024235688,0.00004896189,0.00078537234,0.0000061576907,0.0000109337325,0.00021086728],"genre_scores_gemma":[0.99944717,0.000011575436,0.0001555609,0.00025693554,0.000047839243,0.0000288549,0.0000073412634,0.000023462348,0.000021289788],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986315,0.00032446138,0.00038150366,0.00022422045,0.00022459554,0.00021375316],"domain_scores_gemma":[0.9995065,0.000048738806,0.00016195994,0.00020808402,0.000039967883,0.00003475639],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028798092,0.00014100339,0.00028400592,0.00011450816,0.00005458978,0.0000060294915,0.00016643068,0.00010527053,0.00019102024],"category_scores_gemma":[0.000016312451,0.00009838647,0.00010901633,0.00023825916,0.00014350977,0.00003723235,0.000071342794,0.00019462476,0.0000012305696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005169214,0.00027402164,0.0044629215,0.000063492065,0.000011309821,0.000014750086,0.0010131845,0.00019145738,0.993167,0.00018918038,0.00011046424,0.0004505141],"study_design_scores_gemma":[0.0019143986,0.00011129672,0.07788625,0.00012045313,0.00004221093,9.54157e-7,0.00022350921,0.0001631646,0.91663355,0.00023224618,0.0025816716,0.00009029759],"about_ca_topic_score_codex":0.0004974827,"about_ca_topic_score_gemma":0.000020215843,"teacher_disagreement_score":0.076533474,"about_ca_system_score_codex":0.000028395174,"about_ca_system_score_gemma":0.00003704801,"threshold_uncertainty_score":0.40120837},"labels":[],"label_agreement":null},{"id":"W2007761930","doi":"10.1124/mol.108.046961","title":"Making the T-Type Even Tinier: Corticotropin-Releasing Factor-Mediated Inhibition of Low-Voltage-Activated Calcium Channel Activity","year":2008,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Calcium channel; N-type calcium channel; Chemistry; Calcium; Voltage-dependent calcium channel; T-type calcium channel; Endocrinology; Internal medicine; Biophysics; Cell biology; Biology; Medicine","score_opus":0.16895755323878223,"score_gpt":0.4296650484285155,"score_spread":0.26070749518973324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007761930","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31346616,0.6740062,0.00044943867,0.00032278532,0.0054230755,0.005427646,0.0003485753,0.00032267687,0.00023343677],"genre_scores_gemma":[0.2163758,0.78199536,0.0000018743874,0.0011163057,0.00015505741,0.00014749874,0.000011419314,0.00012239553,0.000074272575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99251163,0.0031432356,0.000886712,0.0013867299,0.00084562716,0.0012260618],"domain_scores_gemma":[0.99643445,0.0015456675,0.0010487776,0.00056035694,0.00018211122,0.00022863965],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008856061,0.0007778797,0.0016953486,0.0006204667,0.0005653894,0.000049099723,0.001150981,0.00049974734,0.00020805272],"category_scores_gemma":[0.00086691946,0.0006031481,0.00056380604,0.0023869057,0.0013777611,0.00022979552,0.000703704,0.002264496,0.00017094983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014308361,0.00032200222,8.540196e-7,0.0012694036,0.000060315637,0.0017903286,0.000056804507,0.000027214744,0.9655754,0.0000049838127,0.0006820097,0.03006759],"study_design_scores_gemma":[0.00068873167,0.0003422748,0.000008806266,0.000560826,0.00022650241,0.0005768819,0.0000027631281,0.0003994919,0.86144406,0.0000059718586,0.13523927,0.000504429],"about_ca_topic_score_codex":0.000009753612,"about_ca_topic_score_gemma":2.543882e-7,"teacher_disagreement_score":0.13455726,"about_ca_system_score_codex":0.00020840127,"about_ca_system_score_gemma":0.0009393064,"threshold_uncertainty_score":0.999642},"labels":[],"label_agreement":null},{"id":"W2008304021","doi":"10.1124/mol.108.050104","title":"Mechanisms of Myocyte Cytotoxicity Induced by the Multiple Receptor Tyrosine Kinase Inhibitor Sunitinib","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Apotex (Canada)","funders":"","keywords":"Sunitinib; AMPK; Myocyte; Pharmacology; Tyrosine-kinase inhibitor; Protein kinase A; Kinase; Tyrosine kinase; Cardiotoxicity; Chemistry; Endocrinology; Biology; Signal transduction; Internal medicine; Medicine; Biochemistry; Toxicity; Cancer","score_opus":0.022644642267746477,"score_gpt":0.27736043942539385,"score_spread":0.25471579715764736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008304021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99291986,0.00021209079,0.0032663834,0.0017887561,0.00039826232,0.0009009009,0.000047376358,0.00007280187,0.0003935408],"genre_scores_gemma":[0.9934348,0.0000813496,0.000500612,0.005420571,0.00015804775,0.00009110869,0.00009755299,0.00004338565,0.00017255898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984702,0.00024009481,0.00034930673,0.00030655236,0.0003129916,0.0003208773],"domain_scores_gemma":[0.9991219,0.00010406995,0.00016187433,0.00027891967,0.00018039675,0.00015285972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025641927,0.00021860699,0.00041019305,0.000092595765,0.00015085078,0.000004742681,0.0001552418,0.00022526551,0.0003002194],"category_scores_gemma":[0.00009505285,0.0001822553,0.00020507959,0.0003080501,0.00020776046,0.00005203896,0.00005812739,0.00040536,0.000024532541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039652572,0.0003080352,0.00003664083,0.00003352053,0.00016926715,0.0000689697,0.00024307884,0.000005933374,0.9935626,0.00010782567,0.0045057754,0.00056182785],"study_design_scores_gemma":[0.0046865344,0.00039885726,0.00027723136,0.00002081565,0.000119344164,0.00014546563,0.000060626273,0.00011366913,0.9915046,0.00006058768,0.0024487816,0.00016347601],"about_ca_topic_score_codex":0.0000563327,"about_ca_topic_score_gemma":0.0000019210293,"teacher_disagreement_score":0.0042900085,"about_ca_system_score_codex":0.00010134897,"about_ca_system_score_gemma":0.00014406114,"threshold_uncertainty_score":0.74321556},"labels":[],"label_agreement":null},{"id":"W2010969866","doi":"10.1124/mol.104.006205","title":"Identification of Amino Acid Residues in the Insect Sodium Channel Critical for Pyrethroid Binding","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Pyrethroid; Sodium channel; Batrachotoxin; Permethrin; Deltamethrin; Binding site; Chemistry; Stereochemistry; Sodium; Allosteric regulation; Biochemistry; Biology; Receptor; Pesticide","score_opus":0.023925651794675675,"score_gpt":0.3182302970319217,"score_spread":0.29430464523724603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010969866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93953127,0.00032080372,0.056496985,0.0023070732,0.00082431943,0.00041646688,0.000016407697,0.00000907684,0.000077609206],"genre_scores_gemma":[0.9984284,0.00003623798,0.0001448689,0.00079641613,0.00026648503,0.00014454735,0.00012752038,0.000015464908,0.00004003472],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903566,0.00012308756,0.00027615103,0.00025201903,0.00010919739,0.00020390518],"domain_scores_gemma":[0.9995922,0.00003333779,0.0000817009,0.00015140616,0.00011193562,0.00002944928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004216549,0.00010626738,0.00011361294,0.00010201627,0.00007314404,0.000011178879,0.00016722393,0.00014496701,0.000008286379],"category_scores_gemma":[0.00018551401,0.00009480302,0.000087354754,0.00013917327,0.00012778817,0.000006026141,0.00003395794,0.00008233341,0.0000040815457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001568125,0.0001047999,0.000036606292,0.000031662825,0.000020084737,0.000004088652,0.00018953299,0.0005870372,0.9973247,0.0009482944,0.00046589144,0.00013050692],"study_design_scores_gemma":[0.0011892482,0.000251648,0.0005787636,0.0000045275797,0.000028010216,0.000015070143,0.0001388027,0.0003341687,0.9952188,0.0010378297,0.0011046545,0.00009847559],"about_ca_topic_score_codex":0.000007710227,"about_ca_topic_score_gemma":0.0000059450717,"teacher_disagreement_score":0.058897167,"about_ca_system_score_codex":0.000023064096,"about_ca_system_score_gemma":0.00005420988,"threshold_uncertainty_score":0.38659552},"labels":[],"label_agreement":null},{"id":"W2012378217","doi":"10.1124/mol.106.029900","title":"Evidence for Direct Regulation of Myocardial Na+/H+ Exchanger Isoform 1 Phosphorylation and Activity by 90-kDa Ribosomal S6 Kinase (RSK): Effects of the Novel and Specific RSK Inhibitor fmk on Responses to α1-Adrenergic Stimulation","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"National Institute of General Medical Sciences; Medical Center, University of Rochester; University of Alberta","keywords":"Ribosomal s6 kinase; MAPK/ERK pathway; Phosphorylation; Kinase; Extracellular; Protein kinase A; Stimulation; Cell biology; Biology; Molecular biology; Myocyte; Biochemistry; Chemistry; Endocrinology; Protein kinase B","score_opus":0.014271902319565863,"score_gpt":0.2697783123206749,"score_spread":0.255506410001109,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012378217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747176,0.0015892399,0.022299135,0.00013085641,0.0003513426,0.0008470693,0.000042218548,0.0000066046755,0.0000159356],"genre_scores_gemma":[0.9988507,0.000083866864,0.00055843504,0.00012888577,0.00016938182,0.00007893727,0.000034569424,0.00002253263,0.00007271386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989152,0.00016072621,0.00021524301,0.0003691594,0.00015689223,0.00018277981],"domain_scores_gemma":[0.9993541,0.00015695472,0.00017847358,0.00015865857,0.0001020606,0.00004975217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002660551,0.00017181794,0.00021576644,0.00006695114,0.0000900999,0.0000115536395,0.00007960328,0.0001605836,0.000009299187],"category_scores_gemma":[0.00009457165,0.00015189225,0.000091379276,0.000110920075,0.00007894969,0.000014460763,0.000078733035,0.00005952803,2.1139793e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001630618,0.00009029207,0.00026885676,0.00006349812,0.00003768786,6.97902e-7,0.000027257252,0.0016353843,0.9930866,0.00007170204,0.00049194554,0.0025954624],"study_design_scores_gemma":[0.0013563336,0.00071247714,0.012462518,0.000051519204,0.00007221772,0.000002287097,0.0000033644703,0.0010902669,0.98320264,0.00004592996,0.000852349,0.0001480924],"about_ca_topic_score_codex":0.00003133041,"about_ca_topic_score_gemma":0.0000029126936,"teacher_disagreement_score":0.024133079,"about_ca_system_score_codex":0.00002913032,"about_ca_system_score_gemma":0.000032070806,"threshold_uncertainty_score":0.6193986},"labels":[],"label_agreement":null},{"id":"W2013386744","doi":"10.1124/mol.62.3.497","title":"Vascular Smooth Muscle Cell Phosphodiesterase (PDE) 3 and PDE4 Activities and Levels are Regulated by Cyclic AMP in Vivo","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"American Society for Pharmacology and Experimental Therapeutics","keywords":"Phosphodiesterase 3; Forskolin; Internal medicine; Vascular smooth muscle; Endocrinology; Phosphodiesterase; Femoral artery; In vivo; Phosphodiesterase inhibitor; Blood vessel; Biology; Medicine; Stimulation; Biochemistry; Enzyme; Smooth muscle","score_opus":0.009857022261957279,"score_gpt":0.23197812232332723,"score_spread":0.22212110006136995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013386744","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989987,0.00812795,0.0005063501,0.00036594347,0.00023750754,0.0003122451,0.000042049443,0.000028192968,0.0003927507],"genre_scores_gemma":[0.995246,0.0013440443,0.00014207559,0.0016213881,0.000055082503,0.000053247855,0.000044461744,0.00004018612,0.0014535021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984929,0.00019998693,0.0002546022,0.00056595734,0.00012341437,0.00036311836],"domain_scores_gemma":[0.99944466,0.000021751259,0.000120906254,0.00023037406,0.00003643664,0.00014587947],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013547756,0.00028152455,0.00026995107,0.00009983875,0.00011128842,0.00003698806,0.00009858826,0.00025386832,0.00028210165],"category_scores_gemma":[0.000015583015,0.00029382936,0.00006856167,0.00012820654,0.00020545145,0.000016810383,0.00013081597,0.00015987306,0.0000063428547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056771652,0.00015055494,0.0010115727,0.000038886767,0.00005154591,0.000029698596,0.00015576667,0.00008578164,0.9868185,0.0000034807044,0.009982968,0.0016144845],"study_design_scores_gemma":[0.0026946675,0.00013642525,0.00630872,0.000014304614,0.000057380632,0.000016765049,0.00007305994,0.00053227664,0.8550734,0.000022523658,0.1346933,0.00037721192],"about_ca_topic_score_codex":0.00003206276,"about_ca_topic_score_gemma":0.0000339376,"teacher_disagreement_score":0.13174511,"about_ca_system_score_codex":0.000029213426,"about_ca_system_score_gemma":0.000013376698,"threshold_uncertainty_score":0.99995136},"labels":[],"label_agreement":null},{"id":"W2013742927","doi":"10.1124/mol.65.1.220","title":"Human Acetyl CoA:Arylamine N-Acetyltransferase Variants Generated by Random Mutagenesis","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Mutagenesis; Enzyme; Biochemistry; Acetyltransferase; Nat; Mutagen; Acetylation; Biology; Acetyl-CoA; Chemistry; Genetics; Gene; Carcinogen; Mutation","score_opus":0.006479132399966541,"score_gpt":0.2735481987026281,"score_spread":0.26706906630266153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013742927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95522106,0.002587962,0.0396557,0.0009124839,0.00025556714,0.0005455646,0.00018840288,0.00005750778,0.00057575974],"genre_scores_gemma":[0.993198,0.00030734597,0.00068162644,0.0033259278,0.00030595492,0.00027692044,0.0010451319,0.000067563604,0.00079155696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982102,0.00015913446,0.0003425427,0.00063202885,0.00014691263,0.000509189],"domain_scores_gemma":[0.99920166,0.0000064328415,0.00008006773,0.00040646183,0.00008548673,0.00021986858],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016879755,0.0003249737,0.00031434675,0.00006931217,0.000215633,0.000025298126,0.00038897726,0.00023366476,0.00019337224],"category_scores_gemma":[0.000015264179,0.00034213558,0.00015539108,0.0002323369,0.0001690155,0.000006332839,0.000104474624,0.00015381625,0.000055357446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085743515,0.00031851995,0.000017750292,0.000009434961,0.00018266455,0.0000419172,0.00001793873,0.00059183384,0.9894632,0.0002282574,0.008564163,0.00047854404],"study_design_scores_gemma":[0.0076502026,0.00019853881,0.00011138355,0.000002355417,0.00016310715,0.000045545472,0.000008301679,0.000025275553,0.9447631,0.00008127149,0.046596643,0.00035424787],"about_ca_topic_score_codex":0.000067297115,"about_ca_topic_score_gemma":0.000009487239,"teacher_disagreement_score":0.044700105,"about_ca_system_score_codex":0.000023014602,"about_ca_system_score_gemma":0.00010567667,"threshold_uncertainty_score":0.9999031},"labels":[],"label_agreement":null},{"id":"W2015755153","doi":"10.1124/mol.108.046458","title":"Targeted Disruption of Murine Organic Anion-Transporting Polypeptide 1b2 (oatp1b2/Slco1b2) Significantly Alters Disposition of Prototypical Drug Substrates Pravastatin and Rifampin","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; Pfizer","keywords":"Organic anion-transporting polypeptide; Organic anion transporter 1; In vivo; Pravastatin; Pharmacokinetics; Pharmacology; Western blot; Transporter; Chemistry; Drug; Biology; Biochemistry; Gene; Cholesterol","score_opus":0.008693675867928614,"score_gpt":0.258540989433717,"score_spread":0.2498473135657884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015755153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99106514,0.00046140284,0.006499596,0.00052381156,0.00011431261,0.0012022775,0.000035748842,0.00005209592,0.000045617275],"genre_scores_gemma":[0.99721193,0.00017740669,0.0020693815,0.00014486049,0.000045306464,0.000057545014,0.00019290295,0.00004136899,0.00005931709],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982746,0.00010873576,0.0006616037,0.00035604698,0.00027640298,0.00032258907],"domain_scores_gemma":[0.9992184,0.000033481516,0.00029437453,0.00014585236,0.00014262287,0.00016523946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021944063,0.00022585719,0.0005144771,0.00015651259,0.000073442236,0.0000027020515,0.00008381433,0.00010997646,0.00020927853],"category_scores_gemma":[0.000010906625,0.00020698714,0.00012246716,0.00027776771,0.00045759193,0.000070182796,0.000012972517,0.00024282213,0.000002495627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001229248,0.00043355091,0.012758929,0.0004883379,0.00014823073,0.00049313024,0.0008435071,0.000030043897,0.98314416,0.00018348491,0.000030398798,0.00021697591],"study_design_scores_gemma":[0.002620212,0.00038935733,0.076221034,0.00009565683,0.0003063379,0.00008280699,0.00021470197,0.00020016634,0.91959095,0.00008083903,0.00003089952,0.00016700965],"about_ca_topic_score_codex":0.0000646781,"about_ca_topic_score_gemma":0.000029148401,"teacher_disagreement_score":0.063553184,"about_ca_system_score_codex":0.000024177054,"about_ca_system_score_gemma":0.00012440438,"threshold_uncertainty_score":0.84406906},"labels":[],"label_agreement":null},{"id":"W2018604540","doi":"10.1124/mol.107.039008","title":"Lipid Composition Alters Drug Action at the Nicotinic Acetylcholine Receptor","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Drug action; Chemistry; Acetylcholine receptor; Nicotinic acetylcholine receptor; Pharmacology; Nicotinic agonist; Acetylcholine; Drug; Action (physics); Composition (language); Receptor; Biochemistry; Biology; Philosophy; Physics","score_opus":0.011557937647129712,"score_gpt":0.3165190804039654,"score_spread":0.3049611427568357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018604540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98651224,0.0010178424,0.0056686597,0.0025439628,0.0024025973,0.0007078128,0.000020046553,0.00006196748,0.0010648504],"genre_scores_gemma":[0.9897257,0.00041168917,0.00059200835,0.0050846073,0.0014523511,0.000064735694,0.00042051688,0.00007753186,0.002170862],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99742556,0.00046120782,0.00048595428,0.0006717166,0.0002724616,0.0006831198],"domain_scores_gemma":[0.99883884,0.00008127831,0.0002514335,0.00050373503,0.00013633563,0.0001883955],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011677261,0.00033886498,0.0002583038,0.00008248342,0.00031276228,0.000020468528,0.00047104235,0.00022773352,0.0005548401],"category_scores_gemma":[0.000051525054,0.00029121657,0.00024228539,0.00023630663,0.00025484228,0.00000802669,0.0004679568,0.0003902566,0.00031524044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044611748,0.00019628623,0.0004904401,0.000010543529,0.0001850688,0.0000024457024,0.000066045824,0.00016836153,0.9131383,0.000015999925,0.08304786,0.0022325413],"study_design_scores_gemma":[0.0015072831,0.00015335817,0.00016380358,0.0000039597435,0.00008630159,0.000056572415,0.000062088795,0.000033216085,0.77867025,0.0000031641532,0.21901418,0.0002458055],"about_ca_topic_score_codex":0.000016969063,"about_ca_topic_score_gemma":0.00007779871,"teacher_disagreement_score":0.13596632,"about_ca_system_score_codex":0.00015465368,"about_ca_system_score_gemma":0.00007089826,"threshold_uncertainty_score":0.999954},"labels":[],"label_agreement":null},{"id":"W2020695556","doi":"10.1124/mol.104.009068","title":"Identification of a Potent and Selective Synthetic Agonist at the CRTH2 Receptor","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"TransCanada (Canada)","funders":"","keywords":"Agonist; Identification (biology); Receptor; Computational biology; Chemistry; Pharmacology; Biology; Biochemistry","score_opus":0.005190862373438755,"score_gpt":0.2524764625936925,"score_spread":0.24728560022025375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020695556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896169,0.0019326806,0.006387542,0.0011978827,0.00017290754,0.0003956616,0.000015520518,0.000008208235,0.00027272356],"genre_scores_gemma":[0.99813855,0.00021829126,0.00025298892,0.0005819829,0.00011995861,0.000082710954,0.000026474092,0.000019103925,0.0005599485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990318,0.00015611503,0.00023052238,0.00029831255,0.00009868938,0.0001845748],"domain_scores_gemma":[0.9995429,0.000014831042,0.00013239427,0.00017184237,0.00008591941,0.000052114647],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002536264,0.000121155994,0.0001221745,0.000030633055,0.00012188851,0.000011473295,0.00014102814,0.00009985348,0.00017672729],"category_scores_gemma":[0.000025389438,0.00009873888,0.00007447978,0.000066544104,0.00014010924,0.0000027587319,0.00012182521,0.00007888337,0.000017620358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081466875,0.000047511065,0.00002382916,0.000008822893,0.000081442966,0.000001266071,0.000068741094,0.00034105137,0.9921567,0.000114887276,0.0017044004,0.0053699226],"study_design_scores_gemma":[0.00037449077,0.0001319534,0.000052026735,0.0000030817187,0.000052375373,0.000024624162,0.000028533126,0.00034404494,0.9703827,0.00003883573,0.028463893,0.00010344871],"about_ca_topic_score_codex":0.000005121982,"about_ca_topic_score_gemma":0.0000052446694,"teacher_disagreement_score":0.026759492,"about_ca_system_score_codex":0.00002668894,"about_ca_system_score_gemma":0.000033115706,"threshold_uncertainty_score":0.40264547},"labels":[],"label_agreement":null},{"id":"W2020879613","doi":"10.1124/mol.110.065193","title":"Identification of 5α,6α-Epoxycholesterol as a Novel Modulator of Liver X Receptor Activity","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Liver X receptor; Oxysterol; Nuclear receptor; Agonist; ABCA1; Context (archaeology); Biology; Chemistry; Receptor; Biochemistry; Cell biology; Cholesterol; Gene; Transcription factor; Transporter","score_opus":0.010729008861455891,"score_gpt":0.30500882669531637,"score_spread":0.2942798178338605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020879613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955296,0.00010410455,0.0016942702,0.00060325157,0.0012579855,0.0005058079,0.00002540927,0.000028914928,0.00025068602],"genre_scores_gemma":[0.9982077,0.000023491171,0.0004561743,0.0006579533,0.00023856986,0.00003819539,0.000010740373,0.000028359535,0.0003388402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987511,0.000072681156,0.00040147043,0.0003120989,0.00025329491,0.00020936166],"domain_scores_gemma":[0.9989098,0.000033972356,0.0003137736,0.00037289923,0.00022354702,0.0001460382],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028808968,0.0001604017,0.0004203957,0.00017047892,0.000024183777,0.0000054392767,0.00015771155,0.0001886974,0.00042018478],"category_scores_gemma":[0.000080076024,0.00015512304,0.0001618431,0.00019004414,0.00018908974,0.00008766283,0.000067109766,0.000373884,0.0000520777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035702318,0.00085198734,0.0005075076,0.00012676818,0.0001392506,0.0000106475,0.00019921936,0.000008443882,0.99216187,0.00021048397,0.0002832441,0.0051435744],"study_design_scores_gemma":[0.0028419804,0.00013936711,0.042512286,0.000012965599,0.0002860827,0.000059625978,0.0000069717053,0.0005687912,0.9470154,0.00001726687,0.0064367484,0.00010253521],"about_ca_topic_score_codex":0.00005167984,"about_ca_topic_score_gemma":0.0000039781353,"teacher_disagreement_score":0.04514647,"about_ca_system_score_codex":0.000015682352,"about_ca_system_score_gemma":0.00009232671,"threshold_uncertainty_score":0.63257337},"labels":[],"label_agreement":null},{"id":"W2024121456","doi":"10.1124/mol.107.041871","title":"Characterization of mENT1Δ11, a Novel Alternative Splice Variant of the Mouse Equilibrative Nucleoside Transporter 1","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Nucleoside; Nucleoside transporter; Biochemistry; Transmembrane protein; Uridine; Transporter; Nucleoside analogue; Transmembrane domain; Chemistry; Mutagenesis; Biology; Molecular biology; RNA; Gene; Mutation; Receptor","score_opus":0.01329370565107205,"score_gpt":0.24715454041593596,"score_spread":0.2338608347648639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024121456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97122836,0.0002024743,0.02765915,0.00018354248,0.00012773818,0.00026029014,0.000072551,0.000004968438,0.00026090987],"genre_scores_gemma":[0.99841225,0.00010219354,0.0003440789,0.0007341778,0.00008994194,0.000021344262,0.00008566103,0.000021446118,0.00018892689],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991048,0.0000900256,0.00028456526,0.00023030453,0.00012957254,0.00016072084],"domain_scores_gemma":[0.9994226,0.000008893831,0.00023118399,0.00019038552,0.0001073789,0.00003955791],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007078462,0.00013698307,0.00018348226,0.00003709915,0.000044388336,0.0000013005438,0.00025193585,0.00009175789,0.00008307705],"category_scores_gemma":[0.0000089338355,0.00011129568,0.0001230206,0.00011678266,0.00016823458,0.000006128106,0.00008567877,0.00008219115,9.887483e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014209871,0.00017631377,0.0002462221,0.0000159567,0.00019335866,0.000017718226,0.0003706342,0.0003930358,0.9978031,0.00015993872,0.000468674,0.0000129413875],"study_design_scores_gemma":[0.0010013417,0.00014605669,0.0008647932,0.000006055535,0.00006708047,0.000045193032,0.000016067386,0.00027076493,0.9959032,0.000012308565,0.0015591593,0.00010796729],"about_ca_topic_score_codex":0.000021656993,"about_ca_topic_score_gemma":6.391689e-7,"teacher_disagreement_score":0.02731507,"about_ca_system_score_codex":0.000007375957,"about_ca_system_score_gemma":0.00007587534,"threshold_uncertainty_score":0.4538506},"labels":[],"label_agreement":null},{"id":"W2024619828","doi":"10.1124/mol.108.048900","title":"The Role of Human Nucleoside Transporters in Uptake of 3′-Deoxy-3′-fluorothymidine","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoside; Uridine; Ribonucleoside; Xenopus; Cell culture; Nucleoside analogue; Fluorescein; Chemistry; Molecular biology; Biology; Biochemistry; RNA; Fluorescence; Genetics","score_opus":0.007792070943926577,"score_gpt":0.25531825416912224,"score_spread":0.24752618322519565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024619828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913881,0.0071712374,0.00016163278,0.0000853179,0.00007203818,0.00017073304,0.0000066735447,0.000005029411,0.00093928387],"genre_scores_gemma":[0.9991351,0.0003728422,0.00011054364,0.00016165571,0.00007303577,0.000021177828,0.000025128536,0.00002152943,0.00007898686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989589,0.00008069588,0.00040273278,0.0002099129,0.00011048167,0.00023727468],"domain_scores_gemma":[0.99954647,0.000014281122,0.00013389994,0.00019983907,0.00005892225,0.00004657738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015910745,0.0001313652,0.00020293312,0.00005608096,0.000067470406,0.0000015054787,0.00026342852,0.00010881582,0.00004378585],"category_scores_gemma":[0.000010035571,0.00011423204,0.00012103146,0.00012449302,0.00022422984,0.0000024125186,0.000045386685,0.0001060974,0.0000010843032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011650379,0.00009269281,0.002756753,0.000009671953,0.0000767459,0.00004475234,0.00011579106,0.00039884614,0.9944977,0.00018812,0.0013341435,0.0003682565],"study_design_scores_gemma":[0.00087915146,0.0002425253,0.0018095793,0.000005761888,0.000030352141,0.000023182316,0.00009326197,0.00005336027,0.9875306,0.000110084125,0.009116826,0.00010535512],"about_ca_topic_score_codex":0.000065218745,"about_ca_topic_score_gemma":0.000007470977,"teacher_disagreement_score":0.007782682,"about_ca_system_score_codex":0.0000068219615,"about_ca_system_score_gemma":0.000058636153,"threshold_uncertainty_score":0.46582472},"labels":[],"label_agreement":null},{"id":"W2024856685","doi":"10.1124/mol.112.081950","title":"Conformational Dynamics of Kir3.1/Kir3.2 Channel Activation Via δ-Opioid Receptors","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Clinical Research Institute; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute on Drug Abuse; Québec Consortium for Drug Discovery; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"G protein-coupled receptor; Chemistry; Ligand (biochemistry); Protein subunit; HEK 293 cells; Biophysics; Conformational change; G protein; Receptor; Stereochemistry; Biochemistry; Biology; Gene","score_opus":0.009019297948500786,"score_gpt":0.2603706746453195,"score_spread":0.25135137669681873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024856685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79712087,0.0001804156,0.19645707,0.00053496164,0.003408278,0.00034577362,0.000023216611,0.000028654465,0.0019007856],"genre_scores_gemma":[0.9964627,0.00003353756,0.00026697587,0.000886248,0.0006384945,0.00003979698,0.0012577403,0.000022596392,0.00039190068],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901164,0.000097790566,0.00027793166,0.00017231554,0.00016155525,0.00027874732],"domain_scores_gemma":[0.99939007,0.000015116879,0.0001821404,0.00013538687,0.00017114638,0.00010616162],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020940279,0.00015226938,0.00014161709,0.000110014684,0.00006658474,0.000005272235,0.0001100718,0.00021062681,0.00026685811],"category_scores_gemma":[0.000037932587,0.00016196915,0.00009841824,0.0001326586,0.00008330233,0.000018935832,0.00006525875,0.00009799582,0.000025760397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017128023,0.00014729517,0.00040502351,0.000029011182,0.000102782615,3.5835515e-7,0.00013682914,0.0014442394,0.9895568,0.00087696745,0.004913985,0.0022154339],"study_design_scores_gemma":[0.00084068015,0.0001466967,0.0007365656,0.0000034551279,0.000031860363,0.000016071293,0.00007377652,0.008366098,0.9597925,0.000117711796,0.029688444,0.00018615491],"about_ca_topic_score_codex":0.000007133615,"about_ca_topic_score_gemma":8.642229e-7,"teacher_disagreement_score":0.19934186,"about_ca_system_score_codex":0.00004880847,"about_ca_system_score_gemma":0.000047580317,"threshold_uncertainty_score":0.660491},"labels":[],"label_agreement":null},{"id":"W2025665881","doi":"10.1124/mol.62.2.257","title":"Apoptosis in Murine Hepatoma Hepa 1c1c7 Wild-Type, C12, and C4 Cells Mediated by Bilirubin","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neonatal Health and Biochemistry","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Health Economics; Children’s Health Research Institute; University of Alberta; Western University","funders":"","keywords":"Aryl hydrocarbon receptor; Apoptosis; Bilirubin; Intracellular; Chemistry; Biochemistry; Caspase; Programmed cell death; Biology; Endocrinology","score_opus":0.009329356748109256,"score_gpt":0.2723348070537911,"score_spread":0.26300545030568184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025665881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98894095,0.0062267394,0.000006302147,0.0032972253,0.00026807838,0.00041424495,0.000026466396,0.00005733214,0.00076266716],"genre_scores_gemma":[0.99031186,0.0016185038,0.00014601456,0.006962487,0.000098415265,0.000034736953,0.000083710795,0.000029002984,0.00071525486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985262,0.000084416606,0.00031543773,0.000412216,0.00017718226,0.00048451682],"domain_scores_gemma":[0.9992655,0.00006149503,0.00006309346,0.00016749615,0.000055367556,0.0003870717],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001307342,0.00020797751,0.00035249483,0.00011517207,0.0000380484,0.0000050922285,0.000095744814,0.00021292856,0.0011197261],"category_scores_gemma":[0.000035938403,0.00019881588,0.00004695475,0.0003675759,0.00012538511,0.000027574968,0.000072682946,0.00035758608,0.00010468102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002124253,0.0002770796,0.0029706368,0.0002193625,0.000039128314,0.00051639613,0.0000352038,5.6817373e-7,0.96823007,0.0000012360183,0.024374982,0.0031229416],"study_design_scores_gemma":[0.0038135222,0.0003127409,0.00028149717,0.000022905228,0.00006907244,0.00009989761,0.0000132213645,0.0010401143,0.96361095,0.0000062759514,0.030553566,0.00017624046],"about_ca_topic_score_codex":0.00011130755,"about_ca_topic_score_gemma":0.0000042668553,"teacher_disagreement_score":0.0061785844,"about_ca_system_score_codex":0.00007361779,"about_ca_system_score_gemma":0.000044297554,"threshold_uncertainty_score":0.9997934},"labels":[],"label_agreement":null},{"id":"W2026449959","doi":"10.1124/mol.107.041087","title":"Progesterone Receptor (PR) Isoforms PRA and PRB Differentially Regulate Expression of the Breast Cancer Resistance Protein in Human Placental Choriocarcinoma BeWo Cells","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Gene isoform; Progesterone receptor; Choriocarcinoma; Biology; Cancer research; Receptor; Human breast; Cancer cell; Cell biology; Breast cancer; Molecular biology; Cancer; Estrogen receptor; Genetics; Gene","score_opus":0.00478473953289882,"score_gpt":0.25471339734520215,"score_spread":0.24992865781230333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026449959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99600387,0.0005701413,0.00019113602,0.0009092378,0.00030775814,0.001785166,0.00003411845,0.000025283276,0.00017330472],"genre_scores_gemma":[0.9973928,0.000029316969,0.00047120106,0.00017821799,0.00008047906,0.000107612934,0.000015563752,0.00003779316,0.0016870708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839157,0.00007997987,0.00043401445,0.0003732604,0.000297852,0.0004233489],"domain_scores_gemma":[0.9993752,0.000009559787,0.00019921677,0.00022185828,0.00006468995,0.00012942776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027519235,0.00022171467,0.00036529606,0.0001069763,0.00008971467,0.000006725144,0.00016367203,0.00016287708,0.00021086051],"category_scores_gemma":[0.0000022072538,0.00015247602,0.00008436996,0.00019737096,0.00020157079,0.000051032137,0.00006799095,0.00031568084,8.854023e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001641122,0.0003276593,0.009048053,0.00037203956,0.00004064068,0.000108528424,0.00028653065,0.00000193055,0.9875484,0.00009670462,0.0001738897,0.00035446684],"study_design_scores_gemma":[0.0035113299,0.000104014754,0.093898706,0.00042484215,0.00008450819,0.000014903128,0.000053222226,0.000005704335,0.9011547,0.000041051382,0.0005633938,0.00014364485],"about_ca_topic_score_codex":0.000036564274,"about_ca_topic_score_gemma":0.0002641582,"teacher_disagreement_score":0.08639375,"about_ca_system_score_codex":0.000110091234,"about_ca_system_score_gemma":0.00008219571,"threshold_uncertainty_score":0.62177914},"labels":[],"label_agreement":null},{"id":"W2030536223","doi":"10.1124/mol.107.040121","title":"Long-Acting β2-Adrenoceptor Agonists Synergistically Enhance Glucocorticoid-Dependent Transcription in Human Airway Epithelial and Smooth Muscle Cells","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Sanofi","keywords":"Glucocorticoid; Agonist; Glucocorticoid receptor; Hormone response element; Endocrinology; Internal medicine; Budesonide; CREB; Adrenergic agonist; Formoterol; Dexamethasone; Pharmacology; Chemistry; Transcription factor; Biology; Receptor; Medicine; Corticosteroid; Gene; Biochemistry","score_opus":0.008698309427610776,"score_gpt":0.30343417740832623,"score_spread":0.29473586798071544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030536223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98519754,0.0007319935,0.011950468,0.00018774408,0.00048483076,0.0005716975,0.000009367292,0.000055744484,0.00081062113],"genre_scores_gemma":[0.99766725,0.000039741408,0.00017260129,0.0015724389,0.00020801219,0.000024642804,0.000014702285,0.0000405271,0.0002600996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982542,0.0001213373,0.00043150544,0.000458239,0.000237295,0.0004974605],"domain_scores_gemma":[0.9993529,0.00005833701,0.00009868471,0.00015140604,0.0000614735,0.0002772273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030549354,0.0002202919,0.00034631015,0.0001663583,0.000090170804,0.00001592666,0.000089669564,0.00015749881,0.000724532],"category_scores_gemma":[0.000026534484,0.00021699807,0.00009759128,0.0001410959,0.00017053842,0.00005274587,0.000038623974,0.00031945607,0.00004010723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003586813,0.00040794586,0.00082124176,0.00014013782,0.000033177672,0.0021051683,0.00013665747,0.00006831546,0.97264975,0.000028903696,0.00004952433,0.023200477],"study_design_scores_gemma":[0.0029222681,0.00046695,0.034167573,0.000046681344,0.00016907466,0.00001715251,0.000077748715,0.00014292826,0.9576751,0.0000106165635,0.00407109,0.0002327997],"about_ca_topic_score_codex":0.000035800935,"about_ca_topic_score_gemma":0.000029147355,"teacher_disagreement_score":0.033346333,"about_ca_system_score_codex":0.000111362875,"about_ca_system_score_gemma":0.00009840707,"threshold_uncertainty_score":0.88489246},"labels":[],"label_agreement":null},{"id":"W2031819924","doi":"10.1124/mol.105.012963","title":"Large-Scale Analysis of Genes that Alter Sensitivity to the Anticancer Drug Tirapazamine in Saccharomyces cerevisiae","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Sanofi","keywords":"Tirapazamine; Saccharomyces cerevisiae; Biochemistry; Biology; Yeast; Chemistry; Cytotoxicity","score_opus":0.009441607420128508,"score_gpt":0.2957305749677946,"score_spread":0.2862889675476661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031819924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98455626,0.0025897422,0.009369347,0.0027555204,0.00019178106,0.00031422207,0.0000800784,0.0000070824613,0.00013597592],"genre_scores_gemma":[0.9921535,0.0005927275,0.00042888193,0.006357349,0.00018339607,0.00004988827,0.000051474108,0.000022378334,0.00016037372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998625,0.00021803344,0.00023604165,0.0004085596,0.00015205912,0.000360328],"domain_scores_gemma":[0.999397,0.000020382402,0.0000936902,0.00034306108,0.000066198874,0.00007968534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004656451,0.00018031144,0.00032946793,0.0001782574,0.00004519079,0.00001070315,0.00021377382,0.0000853243,0.00016206397],"category_scores_gemma":[0.000005274594,0.00015005488,0.00020348167,0.00044683632,0.0000543681,0.000003988401,0.00017343948,0.00010046813,0.000007848021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010308151,0.00012532045,0.0014220922,0.000008525217,0.0006128802,0.000010453389,0.00027937297,0.005268808,0.9861562,0.000039996972,0.0006304529,0.0053428165],"study_design_scores_gemma":[0.00061655295,0.000068701775,0.0021244586,0.0000037866628,0.00046730114,0.000004361041,0.00008721508,0.003964453,0.90925074,0.00000764897,0.08323425,0.00017054843],"about_ca_topic_score_codex":0.000055305187,"about_ca_topic_score_gemma":0.0016698401,"teacher_disagreement_score":0.0826038,"about_ca_system_score_codex":0.000027659271,"about_ca_system_score_gemma":0.00004508004,"threshold_uncertainty_score":0.61190605},"labels":[],"label_agreement":null},{"id":"W2033858438","doi":"10.1124/mol.61.5.1033","title":"Reduced Phosphodiesterase 3 Activity and Phosphodiesterase 3A Level in Synthetic Vascular Smooth Muscle Cells: Implications for Use of Phosphodiesterase 3 Inhibitors in Cardiovascular Tissues","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Phosphodiesterase 3; Vascular smooth muscle; Phosphodiesterase; Biology; Internal medicine; Endocrinology; Contraction (grammar); Context (archaeology); Phenotype; Cell biology; Smooth muscle; Biochemistry; Enzyme; Medicine; Gene","score_opus":0.03605453804352667,"score_gpt":0.27385040718813863,"score_spread":0.23779586914461195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033858438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984017,0.009474196,0.0038245816,0.00037974952,0.00057527015,0.0014936874,0.0001631049,0.000030908028,0.00004149851],"genre_scores_gemma":[0.9948,0.0020488445,0.0017564284,0.00045377485,0.000080071746,0.00056050566,0.00009146694,0.00008271953,0.00012619658],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970074,0.0003881364,0.00070392666,0.0010588417,0.00020827443,0.0006334125],"domain_scores_gemma":[0.99849963,0.00013401861,0.0002431805,0.0007371013,0.00018785357,0.00019820464],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047908226,0.0005009471,0.0007499896,0.000310831,0.00012924385,0.000050073344,0.00023285225,0.0003688688,0.00004214959],"category_scores_gemma":[0.00012918947,0.00054395094,0.0004024596,0.00038676683,0.00031551326,0.00005889396,0.00020884183,0.00024186721,0.0000040221157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000319228,0.0006132839,0.001732861,0.00014364919,0.00025413008,0.000032005624,0.00034244996,0.0029126636,0.9654938,0.00002080504,0.0010125424,0.027122568],"study_design_scores_gemma":[0.0047146757,0.0003517698,0.022069093,0.000080555554,0.00023664498,0.0000142613235,0.0000662033,0.0023188046,0.930519,0.00004655629,0.038904425,0.00067804515],"about_ca_topic_score_codex":0.00035004516,"about_ca_topic_score_gemma":0.00015875173,"teacher_disagreement_score":0.037891883,"about_ca_system_score_codex":0.00011070979,"about_ca_system_score_gemma":0.00006399404,"threshold_uncertainty_score":0.9997012},"labels":[],"label_agreement":null},{"id":"W2039172223","doi":"10.1124/mol.61.3.546","title":"Agonist-Induced Translocation of the Kinin B<sub>1</sub>Receptor to Caveolae-Related Rafts","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"","keywords":"HEK 293 cells; Agonist; Receptor; Chemistry; Molecular biology; Internalization; Biology; Biochemistry","score_opus":0.015330602214649344,"score_gpt":0.258958528877782,"score_spread":0.24362792666313263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039172223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98801047,0.0008743255,0.0002472208,0.00818593,0.0008274457,0.0011463419,0.000009481516,0.00007556243,0.00062323245],"genre_scores_gemma":[0.9954578,0.000052051317,0.000089848545,0.0036866532,0.000115127885,0.000100439516,0.000022995111,0.00004394597,0.00043111632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983625,0.0001801791,0.0004703376,0.00034920158,0.0002810978,0.0003567079],"domain_scores_gemma":[0.9991457,0.000053144126,0.00015015418,0.00030557386,0.00014755048,0.00019787865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017765081,0.00021636284,0.00036268856,0.00014268576,0.000106038635,0.000008568699,0.00019066402,0.00018473355,0.0007462609],"category_scores_gemma":[0.000055237004,0.00018558912,0.00022717072,0.0005630118,0.0001021713,0.000046587167,0.00004342668,0.00022489177,0.0001750364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008583753,0.00024569666,0.0011676182,0.000031593143,0.00016180574,0.0000216757,0.00096377626,0.000124881,0.9804953,0.00021073372,0.0044101523,0.012080963],"study_design_scores_gemma":[0.002661962,0.00024250154,0.009291522,0.000051395033,0.00023377792,0.000039254628,0.000023509421,0.0016630635,0.9818108,0.000043027765,0.003762203,0.00017696153],"about_ca_topic_score_codex":0.000036748082,"about_ca_topic_score_gemma":0.0000079324755,"teacher_disagreement_score":0.011904001,"about_ca_system_score_codex":0.00007872307,"about_ca_system_score_gemma":0.00007484712,"threshold_uncertainty_score":0.8171034},"labels":[],"label_agreement":null},{"id":"W2040386816","doi":"10.1124/mol.107.040964","title":"Multiple Binding Sites for Substrates and Modulators of Semicarbazide-Sensitive Amine Oxidases: Kinetic Consequences","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Benzylamine; Active site; Binding site; Spermidine; Stereochemistry; Enzyme; Substrate (aquarium); Isothermal titration calorimetry; Biochemistry; Biology; Medicinal chemistry","score_opus":0.011111209851874408,"score_gpt":0.2677887541219453,"score_spread":0.2566775442700709,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040386816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99016607,0.0011799313,0.007832984,0.000054627966,0.00026952694,0.0003437856,0.00010081739,0.000011357111,0.00004092149],"genre_scores_gemma":[0.9975099,0.00011895177,0.0016666505,0.0003125944,0.0001405921,0.000015584308,0.00016708531,0.000020789428,0.00004787465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990459,0.00005557881,0.00024860154,0.0003173758,0.000057124485,0.0002754241],"domain_scores_gemma":[0.9995105,0.000069467846,0.00011623976,0.000103626946,0.00012104534,0.000079085126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002455134,0.00015718736,0.00020482912,0.00009161269,0.00005153564,0.0000057377774,0.00007685577,0.0001424981,0.0000104460605],"category_scores_gemma":[0.000108648856,0.00015877333,0.0000728204,0.00009557376,0.00025249255,0.0000043090504,0.000050316794,0.000059273498,0.0000012761005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028664264,0.00004103753,0.0013278897,0.00004208393,0.00009596954,0.000011038838,0.00003379472,0.00008259741,0.9969442,0.00005561932,0.0007191728,0.00035999247],"study_design_scores_gemma":[0.0011400351,0.00024290627,0.0010984418,0.000007019129,0.00009658729,0.00003266337,0.00007337936,0.00012755967,0.9943313,0.000037963437,0.0026508567,0.00016129462],"about_ca_topic_score_codex":0.000028016937,"about_ca_topic_score_gemma":0.000022203374,"teacher_disagreement_score":0.00734383,"about_ca_system_score_codex":0.0000073370734,"about_ca_system_score_gemma":0.000027794733,"threshold_uncertainty_score":0.64745885},"labels":[],"label_agreement":null},{"id":"W2041791844","doi":"10.1124/mol.108.049858","title":"Mitogen-Activated Protein Kinase Pathways Contribute to Hypercontractility and Increased Ca2+ Sensitization in Murine Experimental Colitis","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Colitis; Sensitization; Inflammatory bowel disease; MAPK/ERK pathway; Protein kinase A; Kinase; Contraction (grammar); Endocrinology; Ulcerative colitis; Internal medicine; Medicine; p38 mitogen-activated protein kinases; Chemistry; Immunology; Pharmacology; Biochemistry","score_opus":0.008740669284697177,"score_gpt":0.2628393623684272,"score_spread":0.25409869308373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041791844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996014,0.0008143914,0.0010656605,0.00075480604,0.00007746781,0.0011312851,0.000037064205,0.000024635407,0.000080695216],"genre_scores_gemma":[0.996903,0.000011502036,0.00041448392,0.002230634,0.00009357762,0.00011335771,0.00018999465,0.000018398418,0.000025036874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852014,0.00029156427,0.00026345265,0.00046837842,0.000113527974,0.00034293212],"domain_scores_gemma":[0.99944514,0.000010337151,0.00007097043,0.00016811526,0.000091495865,0.0002139451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020327301,0.00020970058,0.00022579302,0.00010475275,0.00007235737,0.000020654434,0.00007880356,0.00016759217,0.000045494253],"category_scores_gemma":[0.00008785307,0.00024058638,0.000051234096,0.00015845036,0.000049594728,0.000009452759,0.00006355558,0.00011270566,0.0000043742034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000819083,0.0001844828,0.00011900459,0.000009473234,0.000023921793,0.00017107725,0.0000474596,0.00008919007,0.9973259,0.00012581781,0.00008392168,0.0010006878],"study_design_scores_gemma":[0.0029853173,0.00038477578,0.004967283,0.00001652431,0.000014725613,0.00003827589,0.000018439187,0.000304206,0.98919415,0.00007513626,0.0017540737,0.00024706192],"about_ca_topic_score_codex":0.00009911235,"about_ca_topic_score_gemma":0.00002026148,"teacher_disagreement_score":0.008131699,"about_ca_system_score_codex":0.0000627452,"about_ca_system_score_gemma":0.00007418126,"threshold_uncertainty_score":0.9810828},"labels":[],"label_agreement":null},{"id":"W2045594266","doi":"10.1124/mol.105.018705","title":"Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":346,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Aryl hydrocarbon receptor; CYP1B1; Aryl hydrocarbon receptor nuclear translocator; Estrogen receptor; Biology; Gene; Gene expression; Receptor; Regulation of gene expression; Internal medicine; Cytochrome P450; Endocrinology; Cell biology; Molecular biology; Chemistry; Transcription factor; Genetics; Metabolism; Medicine","score_opus":0.005848646491912641,"score_gpt":0.2340419423940502,"score_spread":0.22819329590213758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045594266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934622,0.00045317423,0.00047580412,0.0029617124,0.000441488,0.00034250668,0.000055190132,0.00012311344,0.0016848053],"genre_scores_gemma":[0.99610853,0.000082094724,0.0007983086,0.0018965449,0.00019001594,0.00002354223,0.0000050549047,0.000060398343,0.0008355351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767834,0.00015311538,0.0003522712,0.00069017854,0.00042351428,0.000702556],"domain_scores_gemma":[0.99912024,0.00005152032,0.00013365509,0.00033453642,0.0000026467583,0.00035741416],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003089732,0.00035212343,0.00031684592,0.00006290633,0.00014681173,0.000041337447,0.00038336808,0.00015535849,0.008815503],"category_scores_gemma":[0.00003696825,0.00033892522,0.00007493233,0.00016140586,0.0003875514,0.00021027216,0.0005351218,0.00027361792,0.0007523618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006002656,0.000109086424,0.0021263175,0.0000033188717,0.00006729111,0.0001676924,0.00019210704,0.00010348087,0.96899205,0.0000054368456,0.0009603599,0.027212815],"study_design_scores_gemma":[0.0010967976,0.00011696983,0.042019915,0.0000042175966,0.00008404834,0.00028350818,0.000016407446,0.00049767864,0.9474256,0.00011438328,0.007940663,0.00039981675],"about_ca_topic_score_codex":0.0000502522,"about_ca_topic_score_gemma":0.000048884238,"teacher_disagreement_score":0.039893597,"about_ca_system_score_codex":0.00039268425,"about_ca_system_score_gemma":0.000023092038,"threshold_uncertainty_score":0.9999063},"labels":[],"label_agreement":null},{"id":"W2048347960","doi":"10.1124/mol.107.037150","title":"Inhibition of TRPP3 Channel by Amiloride and Analogs","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Biochemical Analysis and Sensing Techniques","field":"Nursing","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Amiloride; Chemistry; Biophysics; Epithelial sodium channel; Patch clamp; Xenopus; Voltage clamp; Ion channel; Pharmacology; Stereochemistry; Biochemistry; Receptor; Membrane potential; Sodium; Biology","score_opus":0.007563535229323409,"score_gpt":0.2801115498432076,"score_spread":0.27254801461388417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048347960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882024,0.00056696474,0.008988278,0.0012536052,0.00012233673,0.00008979678,0.000005485668,0.00005477549,0.00071636937],"genre_scores_gemma":[0.99691725,0.000023386123,0.0005508184,0.0024202948,0.000041242078,0.0000017394997,0.000022172608,0.000010888765,0.000012219569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928606,0.000048804483,0.00020800065,0.00018277597,0.00008730064,0.00018703475],"domain_scores_gemma":[0.999701,0.000033352426,0.00007871068,0.00007122103,0.00005277572,0.00006292945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023308388,0.000090689566,0.00017978658,0.0000964803,0.000031791144,0.000004373356,0.00004279917,0.000108671666,0.000017658373],"category_scores_gemma":[0.000014089385,0.00008911296,0.000057283774,0.00015651013,0.0001272682,0.000021961992,0.000024658742,0.00011569156,0.0000012974648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000099758756,0.00006076284,0.000038777256,0.0000132939795,0.0000289536,0.000020400817,0.00004934259,8.2107744e-7,0.98818797,0.00006273819,0.008736987,0.0027002138],"study_design_scores_gemma":[0.00034501243,0.00011722583,0.00008715218,0.0000068946533,0.000091826005,0.000009025052,0.000012436093,0.00024647432,0.99623966,0.0014975116,0.0012573844,0.000089396424],"about_ca_topic_score_codex":0.000056765755,"about_ca_topic_score_gemma":0.000003058481,"teacher_disagreement_score":0.00871485,"about_ca_system_score_codex":0.000021168285,"about_ca_system_score_gemma":0.000002501257,"threshold_uncertainty_score":0.3633921},"labels":[],"label_agreement":null},{"id":"W2050037509","doi":"10.1124/mol.65.1.157","title":"Site within N-Methyl-D-aspartate Receptor Pore Modulates Channel Gating","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"NMDA receptor; Biophysics; Glutamate receptor; Chemistry; Gating; Excitotoxicity; Desensitization (medicine); Ion channel; Voltage-dependent calcium channel; Extracellular; Receptor; Ligand-gated ion channel; Calcium; Biochemistry; Cell biology; Biology","score_opus":0.03859293166520371,"score_gpt":0.34548692830966243,"score_spread":0.3068939966444587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050037509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922092,0.000079336416,0.00031090854,0.0038180184,0.0020683485,0.0006840298,0.000026487882,0.00027465928,0.00052904245],"genre_scores_gemma":[0.983072,0.0001317266,0.00017595067,0.015793912,0.00017073311,0.00013834043,0.000004643133,0.00007465813,0.0004380533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99586546,0.0006917937,0.00046265256,0.0012572773,0.00056255655,0.0011602459],"domain_scores_gemma":[0.9987499,0.00023410971,0.000200235,0.00033324276,0.00008763093,0.0003948729],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00048754324,0.00037740503,0.0003581791,0.00033032833,0.0005098981,0.00007763502,0.00080475694,0.00014617454,0.00031379858],"category_scores_gemma":[0.00039744057,0.00036898724,0.00014755556,0.0010654748,0.0006833174,0.00031308757,0.00037850515,0.00087001215,0.00088862027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012119057,0.0002224099,0.000024485607,0.000018369321,0.000013645168,0.002287786,0.00039353143,0.014882002,0.98093975,0.0003908024,0.0005017751,0.00020427791],"study_design_scores_gemma":[0.0019960762,0.000373746,0.000018934317,0.000009902564,0.000034424153,0.0002310564,0.0000206113,0.00312084,0.9915221,0.00085820386,0.0014677345,0.00034640537],"about_ca_topic_score_codex":0.000019990955,"about_ca_topic_score_gemma":0.0000012758996,"teacher_disagreement_score":0.011975894,"about_ca_system_score_codex":0.000089960624,"about_ca_system_score_gemma":0.00019172877,"threshold_uncertainty_score":0.9998893},"labels":[],"label_agreement":null},{"id":"W2056176294","doi":"10.1124/mol.105.021667","title":"RanGAP-Mediated Nuclear Protein Import in Vascular Smooth Muscle Cells Is Augmented by Lysophosphatidylcholine","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute","keywords":"Lysophosphatidylcholine; Cell biology; Protein kinase A; MAPK/ERK pathway; Nuclear protein; Nuclear transport; Vascular smooth muscle; Biology; Intracellular; Cytosol; Nuclear export signal; Nuclear localization sequence; Cell growth; Kinase; Molecular biology; Cell nucleus; Cytoplasm; Biochemistry; Endocrinology; Transcription factor; Gene; Enzyme","score_opus":0.002261849480805429,"score_gpt":0.2057973905281737,"score_spread":0.20353554104736826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056176294","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99589854,0.0012622144,0.00040863824,0.00041785045,0.00033821614,0.00063366204,0.000055940167,0.000045650362,0.00093927543],"genre_scores_gemma":[0.9941606,0.00010984957,0.00041624013,0.00403477,0.00019646733,0.00005864157,0.00055019953,0.00008790926,0.00038531332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981899,0.00014846462,0.00037792212,0.0006109858,0.0001963093,0.00047639705],"domain_scores_gemma":[0.99938697,0.000005262064,0.00012759332,0.00031720757,0.00005961173,0.00010334325],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018362865,0.0002892998,0.00026002826,0.00010095872,0.000072472576,0.000021143107,0.00023669082,0.00032281314,0.0006569962],"category_scores_gemma":[0.000010012519,0.00030802275,0.00015730505,0.00022586007,0.00009800352,0.000008046585,0.00011175001,0.00023379773,0.00007733314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013585537,0.00018892698,0.000109799235,0.000014013164,0.0000637614,0.000057600115,0.000015395824,0.00008487155,0.9424726,0.000019082578,0.056222986,0.0006151304],"study_design_scores_gemma":[0.0023687049,0.00017055174,0.0012699103,0.0000043991727,0.000041139392,0.0000020267275,0.000008784806,0.00029270668,0.61819625,0.000037029466,0.37734658,0.0002619402],"about_ca_topic_score_codex":0.00021729813,"about_ca_topic_score_gemma":0.000012794811,"teacher_disagreement_score":0.32427636,"about_ca_system_score_codex":0.00004531451,"about_ca_system_score_gemma":0.000047291676,"threshold_uncertainty_score":0.9999372},"labels":[],"label_agreement":null},{"id":"W2056643428","doi":"10.1124/mol.108.045625","title":"Formaldehyde-Activated Pixantrone Is a Monofunctional DNA Alkylator That Binds Selectively to CpG and CpA Doublets","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre for Drug Research and Development","funders":"","keywords":"CpG site; Chemistry; DNA; Formaldehyde; Molecular biology; Biophysics; Biochemistry; Biology; DNA methylation; Gene","score_opus":0.019078134264579695,"score_gpt":0.266928108929604,"score_spread":0.24784997466502431,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056643428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845673,0.00067264907,0.012372821,0.0010157061,0.000418404,0.00042945513,0.000045365727,0.000030260406,0.00044802768],"genre_scores_gemma":[0.9871692,0.00030308217,0.0005345518,0.010869484,0.0001981208,0.0002048056,0.000055173918,0.000050928662,0.00061463466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852943,0.00006342095,0.00018374986,0.00056807144,0.00017633321,0.00047900644],"domain_scores_gemma":[0.9993588,0.000008573343,0.00007816396,0.00019687484,0.0001126602,0.0002449582],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010165035,0.00027309748,0.0002383066,0.000115434115,0.00019437779,0.000016592847,0.00016655565,0.00020273059,0.00022778139],"category_scores_gemma":[0.0000055303994,0.00028543346,0.00009780709,0.0001735543,0.00008990301,0.00000868328,0.0001695109,0.00015261573,0.000021196778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007739645,0.000094950454,0.0001454557,0.000007818799,0.00030894746,0.000041571668,0.00009715759,0.000042074324,0.99095523,0.0001187748,0.0061124903,0.0013015502],"study_design_scores_gemma":[0.0018919643,0.00073654484,0.0005361449,0.000002814066,0.0000571573,0.00020831918,0.000014096179,0.00009986734,0.85940874,0.00007615251,0.13668041,0.00028780007],"about_ca_topic_score_codex":0.000024444795,"about_ca_topic_score_gemma":0.0000044989774,"teacher_disagreement_score":0.13154651,"about_ca_system_score_codex":0.000048511425,"about_ca_system_score_gemma":0.00015421517,"threshold_uncertainty_score":0.99995977},"labels":[],"label_agreement":null},{"id":"W2057205380","doi":"10.1124/mol.105.019976","title":"A Nonpeptide Antagonist Reveals a Highly Glycosylated State of the Rabbit Kinin B1 Receptor","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Centre Hospitalier Universitaire de Québec","keywords":"Receptor; HEK 293 cells; Biology; B-cell receptor; Proteasome; Molecular biology; Endoplasmic reticulum; G protein-coupled receptor; Cell biology; Biochemistry; B cell; Antibody; Immunology","score_opus":0.006476060767791704,"score_gpt":0.2548251252701371,"score_spread":0.24834906450234542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057205380","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99105877,0.0016105311,0.00025106943,0.0036811554,0.0006951165,0.00074137584,0.000053543852,0.00008986851,0.001818593],"genre_scores_gemma":[0.9923661,0.00005151578,0.0004171702,0.0025289494,0.00020606334,0.00004048034,0.00008321015,0.000050909806,0.004255654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805945,0.00021622822,0.00060255174,0.00036705396,0.0003081372,0.00044655162],"domain_scores_gemma":[0.99897313,0.000082012506,0.00029974614,0.0003407414,0.00018380121,0.00012059052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025896163,0.00025017431,0.00048644937,0.00012172751,0.00011666071,0.000013081822,0.00021917178,0.0001124956,0.00048809347],"category_scores_gemma":[0.00004188702,0.00019830266,0.00026848543,0.00047599548,0.00025135308,0.000047440506,0.00009734952,0.00022677642,0.00006372388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038817732,0.0002562283,0.011723721,0.0000655228,0.00016761688,0.00011238729,0.00010753104,0.00015348665,0.96237814,0.0003365722,0.023172611,0.0011380205],"study_design_scores_gemma":[0.0037282684,0.00023093303,0.051520303,0.00006617777,0.00031482664,0.00007583369,0.0000086964355,0.00033937703,0.9000237,0.00059717917,0.042879157,0.00021554828],"about_ca_topic_score_codex":0.00033167182,"about_ca_topic_score_gemma":0.000022075326,"teacher_disagreement_score":0.062354423,"about_ca_system_score_codex":0.000086939515,"about_ca_system_score_gemma":0.00018964158,"threshold_uncertainty_score":0.8086548},"labels":[],"label_agreement":null},{"id":"W2058606901","doi":"10.1124/mol.65.4.917","title":"Atrial Natriuretic Peptide-C Receptor-Induced Attenuation of Adenylyl Cyclase Signaling Activates Phosphatidylinositol Turnover in A10 Vascular Smooth Muscle Cells","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Adenylyl cyclase; Phosphatidylinositol; NPR1; Receptor; NPR2; ADCY9; Chemistry; Vascular smooth muscle; Natriuretic peptide; Internal medicine; Cell biology; Endocrinology; Signal transduction; Biochemistry; Smooth muscle; Biology; Medicine; Heart failure","score_opus":0.008586326219733941,"score_gpt":0.2514980224769917,"score_spread":0.24291169625725778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058606901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99230504,0.0010519976,0.004799292,0.0001339643,0.0009613435,0.00065632665,0.000016637376,0.000022430133,0.00005298217],"genre_scores_gemma":[0.9970463,0.00017074261,0.0018237894,0.0003086066,0.00041399608,0.000040941548,0.00011030152,0.00006807091,0.00001724907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997584,0.00027434522,0.0006200372,0.00067087496,0.0003332375,0.0005175264],"domain_scores_gemma":[0.99904823,0.000040702555,0.00029824954,0.0003022225,0.00016584645,0.00014476776],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045641494,0.00035391186,0.00043391623,0.00018681411,0.000081069105,0.000023677227,0.000339916,0.0004345881,0.00035202331],"category_scores_gemma":[0.00006226909,0.0003815989,0.00039703026,0.00031469678,0.0000774237,0.00001766169,0.0001041725,0.00032379862,0.00002021185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023270558,0.00017258708,0.000061844315,0.000040712697,0.00015509895,0.00003370942,0.00021405285,0.019527534,0.9787225,0.000063734566,0.00010112075,0.0006744156],"study_design_scores_gemma":[0.0046000853,0.00045063955,0.00010883421,0.000042178286,0.00011963277,0.0000024634876,0.00008170187,0.00015064236,0.991536,0.00014596268,0.0023730383,0.0003888074],"about_ca_topic_score_codex":0.00010142196,"about_ca_topic_score_gemma":0.000010138786,"teacher_disagreement_score":0.01937689,"about_ca_system_score_codex":0.00010216268,"about_ca_system_score_gemma":0.00019821689,"threshold_uncertainty_score":0.99986356},"labels":[],"label_agreement":null},{"id":"W2059597638","doi":"10.1124/mol.105.016527","title":"N-Substituted 4-Aminobenzamides (Procainamide Analogs): An Assessment of Multiple Cellular Effects Concerning Ion Trapping","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ginger and Zingiberaceae research","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Universidad de Salamanca; Centre Hospitalier Universitaire de Québec","keywords":"Apoptosis; Bafilomycin; Chemistry; Cell growth; Programmed cell death; Viability assay; Biochemistry; Cell biology; Pharmacology; Biology; Molecular biology","score_opus":0.08553218248838816,"score_gpt":0.47720367077140236,"score_spread":0.3916714882830142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059597638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9765988,0.0019216947,0.016127964,0.00051757,0.0012637671,0.0010622476,0.000021198332,0.00019250106,0.0022942785],"genre_scores_gemma":[0.9953374,0.00016225684,0.002342546,0.0012512247,0.00046477988,0.00018204049,0.00009953643,0.00006805108,0.000092165785],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952005,0.0019054133,0.00070469256,0.000721009,0.0004009332,0.0010674151],"domain_scores_gemma":[0.99780786,0.00081206445,0.00030176065,0.00032520847,0.00025917395,0.0004939099],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015271951,0.00044296723,0.0006658436,0.00044967412,0.00036533215,0.000029649691,0.0006137371,0.00047736478,0.0009746973],"category_scores_gemma":[0.00011216594,0.00047334612,0.00023050682,0.000510013,0.00044216352,0.00029741268,0.00018645312,0.0014657594,0.000051234245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021596711,0.00086402294,0.0068037636,0.00024810075,0.0004902371,0.00042648573,0.00057281036,0.022704326,0.9464949,0.00078350975,0.00044111352,0.019954806],"study_design_scores_gemma":[0.004231608,0.0002998921,0.0040614884,0.000026954438,0.00033288938,0.00003331398,0.000075550604,0.13359794,0.84439343,0.00008095228,0.012454812,0.00041113395],"about_ca_topic_score_codex":0.000044269716,"about_ca_topic_score_gemma":0.000019612475,"teacher_disagreement_score":0.110893615,"about_ca_system_score_codex":0.0002518212,"about_ca_system_score_gemma":0.00027318468,"threshold_uncertainty_score":0.99993855},"labels":[],"label_agreement":null},{"id":"W2060952492","doi":"10.1124/mol.104.001081","title":"An Investigation of the Neuroprotective Effects of Tetracycline Derivatives in Experimental Models of Retinal Cell Death","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Minocycline; Excitotoxicity; Neuroprotection; Glutamate receptor; Retinal; Biology; Apoptosis; Dizocilpine; Pharmacology; Programmed cell death; NMDA receptor; Neuroscience; Cell biology; Receptor; Biochemistry","score_opus":0.007487269392021107,"score_gpt":0.26376185642884276,"score_spread":0.25627458703682165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060952492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968355,0.00041128937,0.0020881272,0.00004113408,0.000067016575,0.00038475957,0.000001868473,0.0000020894947,0.00016823228],"genre_scores_gemma":[0.9985679,0.000029206965,0.0012026953,0.0001360102,0.000009165471,0.000029145995,0.000009714485,0.000011974835,0.000004222935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991521,0.00019010858,0.00023996316,0.00019421506,0.00010379429,0.00011976755],"domain_scores_gemma":[0.99959654,0.000011127026,0.00017045315,0.00013074039,0.00006042838,0.000030705567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008714225,0.000108805674,0.00014986077,0.00005513683,0.00001658421,0.0000012546814,0.00018245245,0.000077640296,0.0000037179257],"category_scores_gemma":[0.000019050933,0.000093869385,0.000060712326,0.00013367162,0.0001831857,0.0000063911257,0.00007020911,0.00007818246,1.5982467e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017634027,0.00021454967,0.0046449904,0.00006274905,0.000018689756,0.000004364449,0.0004469028,0.0048520053,0.98940426,0.00013854582,0.000003585991,0.00003299015],"study_design_scores_gemma":[0.0015700967,0.00063195307,0.016978128,0.000018590532,0.000015881174,0.0000020462578,0.000091008806,0.00013774783,0.97977006,0.0007007993,0.000002134412,0.000081565966],"about_ca_topic_score_codex":0.0000376703,"about_ca_topic_score_gemma":0.0000021829885,"teacher_disagreement_score":0.012333138,"about_ca_system_score_codex":0.000011962315,"about_ca_system_score_gemma":0.00009653265,"threshold_uncertainty_score":0.38278824},"labels":[],"label_agreement":null},{"id":"W2061132293","doi":"10.1124/mol.62.3.608","title":"Common Human UGT1A Polymorphisms and the Altered Metabolism of Irinotecan Active Metabolite 7-Ethyl-10-hydroxycamptothecin (SN-38)","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":341,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Burroughs Wellcome Fund","keywords":"Glucuronidation; Metabolite; SN-38; Microsome; Glucuronosyltransferase; Irinotecan; UGT2B7; Glucuronide; Toxicity; Active metabolite; Chemistry; Isozyme; Metabolism; Enzyme; In vitro; Biochemistry; Pharmacology; Biology; Genetics; Cancer; Colorectal cancer","score_opus":0.01304431530848102,"score_gpt":0.2737408960482914,"score_spread":0.2606965807398104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061132293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781931,0.015486842,0.001155806,0.0011512468,0.0005076774,0.0006568225,0.00008470215,0.000020826208,0.0027429594],"genre_scores_gemma":[0.9945633,0.0013301201,0.00012863417,0.0025670433,0.0002839948,0.000104046085,0.000042657062,0.00005491464,0.0009252809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99812984,0.00041595232,0.00037449272,0.00047634763,0.00018612007,0.00041722797],"domain_scores_gemma":[0.99904335,0.00003002964,0.00024475102,0.00046434268,0.00008892681,0.00012860665],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002930768,0.00030721407,0.0005054716,0.00009417726,0.00015362923,0.000020062467,0.00039599853,0.00019687768,0.0005634742],"category_scores_gemma":[0.00001128755,0.00024951342,0.00022782132,0.00013820961,0.000512952,0.0000060568077,0.00025481856,0.00022044023,0.000008574529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036190834,0.00014151374,0.0000055256965,0.000011784547,0.00053594436,0.000008716265,0.0002524893,0.00003553363,0.9888719,0.0034218295,0.0005788935,0.0057739774],"study_design_scores_gemma":[0.0047883075,0.00025593027,0.00009739654,0.0000038320036,0.00034077634,0.00003356398,0.000032851694,0.00027075247,0.91809076,0.001109468,0.07472509,0.00025129004],"about_ca_topic_score_codex":0.00010514338,"about_ca_topic_score_gemma":0.000016425369,"teacher_disagreement_score":0.0741462,"about_ca_system_score_codex":0.000015375608,"about_ca_system_score_gemma":0.000024813246,"threshold_uncertainty_score":0.9999957},"labels":[],"label_agreement":null},{"id":"W2063835667","doi":"10.1124/mol.112.079715","title":"Common Mechanisms of Drug Interactions with Sodium and T-Type Calcium Channels","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Voltage-dependent calcium channel; Biophysics; Gating; Chemistry; T-type calcium channel; Binding site; Sodium channel; Calcium; Calcium channel; Biochemistry; Sodium; Biology","score_opus":0.014967125242319891,"score_gpt":0.29308124078786113,"score_spread":0.2781141155455412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063835667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9690823,0.00031412748,0.027395766,0.00038205177,0.00196718,0.00019866464,0.000005598528,0.000014863599,0.0006394708],"genre_scores_gemma":[0.9978508,0.000020893089,0.00039181364,0.0007087207,0.00030233717,0.000020713778,0.00008113054,0.000019914138,0.0006037114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993154,0.000092744565,0.00013767867,0.00016701869,0.00007809968,0.00020905239],"domain_scores_gemma":[0.99960107,0.000011400071,0.0000810622,0.000113789254,0.000092028116,0.00010063663],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001195293,0.00011992708,0.00013068256,0.000065122375,0.000054581615,0.0000053975423,0.00006132736,0.000060286973,0.000081017366],"category_scores_gemma":[0.000009068159,0.000108901535,0.00003633531,0.00008955881,0.00007659432,0.0000080436275,0.00006684997,0.00008259863,0.000006090926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023660697,0.0000977387,0.0006034523,0.000014941579,0.000081600374,0.0000021726362,0.00008970577,0.0001412043,0.99598134,0.0006470391,0.0018476585,0.00025655073],"study_design_scores_gemma":[0.0006755305,0.00019042882,0.0003704905,0.000003473637,0.000056581932,0.000060819624,0.00008243481,0.0003700762,0.9803346,0.000078953446,0.01765247,0.0001241299],"about_ca_topic_score_codex":0.000012085619,"about_ca_topic_score_gemma":0.000002862492,"teacher_disagreement_score":0.02876849,"about_ca_system_score_codex":0.000009569113,"about_ca_system_score_gemma":0.000021816062,"threshold_uncertainty_score":0.4440876},"labels":[],"label_agreement":null},{"id":"W2064080294","doi":"10.1124/mol.104.006817","title":"Isoform-Specific Regulation of Adenylyl Cyclase Function by Disruption of Membrane Trafficking","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Adenylyl cyclase; ADCY10; ADCY6; cAMP-dependent pathway; ADCY9; Cell biology; ADCY3; Gs alpha subunit; Biology; Biochemistry; Chemistry; Signal transduction","score_opus":0.006624222846956806,"score_gpt":0.2332467659836002,"score_spread":0.2266225431366434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064080294","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8364565,0.0012456252,0.16154654,0.00006973831,0.00024150731,0.00021727216,0.000018546842,0.000012701796,0.00019159277],"genre_scores_gemma":[0.99648845,0.0003139981,0.0002496877,0.00008877148,0.00008474824,0.000015023446,0.002677404,0.000024731768,0.000057207373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989448,0.000056678145,0.0003609395,0.0002888009,0.00015933781,0.0001894059],"domain_scores_gemma":[0.9994775,0.0000045911434,0.00018676597,0.00017652917,0.00009808385,0.00005653683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014882786,0.00015085746,0.0001924675,0.00008249261,0.000040645667,0.0000038253647,0.000104711944,0.00020413392,0.000108849286],"category_scores_gemma":[0.000004726027,0.00016574131,0.00014672366,0.00013954383,0.0001138523,0.000008374784,0.000020326499,0.000088120294,0.0000035437095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045132052,0.00018006195,0.000106655374,0.0000516378,0.00007664146,0.000004010238,0.000054367134,0.0046346877,0.993014,0.0002978395,0.000095228206,0.0010335485],"study_design_scores_gemma":[0.0018881981,0.00039945668,0.0011095149,0.000011696354,0.00009169679,0.000010308784,0.000023934603,0.000104126695,0.9839758,0.000092305825,0.012146747,0.00014616386],"about_ca_topic_score_codex":0.0000122319425,"about_ca_topic_score_gemma":0.0000051183783,"teacher_disagreement_score":0.16129686,"about_ca_system_score_codex":0.000023532253,"about_ca_system_score_gemma":0.00004028113,"threshold_uncertainty_score":0.6758734},"labels":[],"label_agreement":null},{"id":"W2066392191","doi":"10.1124/mol.61.6.1476","title":"Selective Down-Regulation of c-<i>jun</i>Gene Expression by Pentoxifylline and c-<i>jun</i>Antisense Interrupts Platelet-Derived Growth Factor Signaling: Pentoxifylline Inhibits Phosphorylation of c-Jun on Serine 73","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Pentoxifylline; Platelet-derived growth factor receptor; Platelet-derived growth factor; c-jun; Phosphorylation; Cell biology; Biology; Signal transduction; Molecular biology; Growth factor; Cancer research; Receptor; Pharmacology; Biochemistry; Gene; Transcription factor","score_opus":0.015439700246349341,"score_gpt":0.27230910892690635,"score_spread":0.256869408680557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066392191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943835,0.0011154381,0.0019599458,0.0009488764,0.0001415572,0.0010718297,0.00014439684,0.00006032715,0.00017414287],"genre_scores_gemma":[0.99714106,0.0004219901,0.0010311706,0.0006746371,0.00008138227,0.000066318586,0.00036234185,0.000043146367,0.00017792534],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979304,0.00021010207,0.00069211965,0.0005724724,0.00025948387,0.0003354273],"domain_scores_gemma":[0.9986403,0.0001543915,0.00045878437,0.00022779206,0.00033459786,0.00018413324],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016371859,0.00034469392,0.00062061305,0.00022688377,0.00009812646,0.000006067972,0.00012166173,0.000317469,0.0006730267],"category_scores_gemma":[0.000076961376,0.00032071694,0.00012491722,0.00038839428,0.00025253955,0.00008609833,0.000085813284,0.00037845678,0.000018897961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011717232,0.00077332364,0.00083444064,0.00012941397,0.00018372605,0.000019621342,0.00033737023,0.00011282158,0.993727,0.00004807148,0.0019041888,0.0007582551],"study_design_scores_gemma":[0.0041109635,0.0010380562,0.0029893601,0.00009278356,0.00016586136,0.00005158492,0.000019740759,0.0016087026,0.98909074,0.00007035882,0.00051941647,0.00024244357],"about_ca_topic_score_codex":0.000019815929,"about_ca_topic_score_gemma":0.0000016400976,"teacher_disagreement_score":0.004636316,"about_ca_system_score_codex":0.00006355959,"about_ca_system_score_gemma":0.00003090075,"threshold_uncertainty_score":0.9999245},"labels":[],"label_agreement":null},{"id":"W2067983199","doi":"10.1124/mol.61.4.710","title":"p75-Nerve Growth Factor as an Antiapoptotic Complex: Independence versus Cooperativity in Protection from Enediyne Chemotherapeutic Agents","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute","keywords":"Enediyne; Cooperativity; Independence (probability theory); Nerve growth factor; Chemistry; Pharmacology; Stereochemistry; Biochemistry; Biology; Receptor; Mathematics","score_opus":0.05627308788616669,"score_gpt":0.3338857356588448,"score_spread":0.2776126477726781,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067983199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941594,0.00020500418,0.0030349244,0.00046209226,0.0007210939,0.0007825133,0.000044800912,0.000042439926,0.0005477228],"genre_scores_gemma":[0.997661,0.000077695084,0.0004191076,0.0011055577,0.00020454677,0.00020149117,0.00013094438,0.000051988878,0.0001476521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99780566,0.0005211377,0.0002995135,0.00072241575,0.00022321017,0.00042805902],"domain_scores_gemma":[0.99921644,0.000024882998,0.00012498538,0.00034330884,0.00014298022,0.00014739422],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011572871,0.0003001682,0.0002517377,0.00012102257,0.00011247437,0.000041472358,0.0003506461,0.00032141953,0.0023792915],"category_scores_gemma":[0.000091223956,0.00033816334,0.00009605191,0.0002177343,0.00012129404,0.000028765873,0.0001342265,0.00041356563,0.00015336505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037413748,0.00047335477,0.0005540751,0.000009902084,0.00016756171,0.00006784659,0.00011911343,0.0001270262,0.9961749,0.000016181071,0.0002481668,0.0016677657],"study_design_scores_gemma":[0.0033819503,0.00087953405,0.004024135,0.000008565977,0.000050024944,0.00003297987,0.00002801248,0.0034505,0.985215,0.00006955335,0.0024897426,0.00036996682],"about_ca_topic_score_codex":0.0005415838,"about_ca_topic_score_gemma":0.00017536452,"teacher_disagreement_score":0.010959835,"about_ca_system_score_codex":0.0000946932,"about_ca_system_score_gemma":0.000052536237,"threshold_uncertainty_score":0.999907},"labels":[],"label_agreement":null},{"id":"W2072497459","doi":"10.1124/mol.61.4.707","title":"Deactivation of Vasodilator Responses by GRK2 Overexpression:<i>A</i> Mechanism or <i>the</i> Mechanism for Hypertension?","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Mechanism (biology); Vasodilation; Medicine; Disease; Ideal (ethics); Statement (logic); Internal medicine; Cardiology; Intensive care medicine; Philosophy; Epistemology","score_opus":0.020732852954499933,"score_gpt":0.265976725882313,"score_spread":0.24524387292781308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072497459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8998301,0.0007087247,0.09647281,0.00105936,0.00068658596,0.0009897614,0.00011166907,0.000031780113,0.000109219865],"genre_scores_gemma":[0.99029577,0.0003706433,0.0026501492,0.0049670655,0.00019875636,0.00024855728,0.00006939308,0.00006239721,0.0011372835],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833935,0.00021796035,0.0003799448,0.00047296012,0.00022086797,0.00036890054],"domain_scores_gemma":[0.99899244,0.000109468536,0.00023730227,0.00032179256,0.00023595794,0.000103063896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029985415,0.00025440587,0.00028772475,0.000055814846,0.00018759423,0.000016189066,0.0003293409,0.00026750675,0.0005779539],"category_scores_gemma":[0.00014545178,0.00017097044,0.00019202051,0.00011954198,0.00006543872,0.000008678162,0.00011911652,0.00012567233,0.0000068384857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005165815,0.0001429766,0.0000021578633,0.000019764166,0.0001200497,0.000007467935,0.000033570683,0.000015651169,0.9674547,0.0018403563,0.02935084,0.0004959306],"study_design_scores_gemma":[0.0015740308,0.00064329704,9.4899025e-7,0.000014246051,0.000078778045,0.00004324421,0.00004846907,0.00086924335,0.9660775,0.0015555666,0.028860768,0.0002339221],"about_ca_topic_score_codex":0.000007905514,"about_ca_topic_score_gemma":7.479813e-7,"teacher_disagreement_score":0.09382266,"about_ca_system_score_codex":0.000017328,"about_ca_system_score_gemma":0.000043894142,"threshold_uncertainty_score":0.6971972},"labels":[],"label_agreement":null},{"id":"W2080845586","doi":"10.1124/mol.114.095653","title":"Monepantel Irreversibly Binds to and Opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 Receptors","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Helminth infection and control","field":"Veterinary","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Homomeric; Haemonchus contortus; Betaine; Caenorhabditis elegans; Biology; Allosteric regulation; Anthelmintic; Ion channel; Receptor; Pharmacology; Biochemistry; Protein subunit; Nematode; Gene","score_opus":0.017891019450718443,"score_gpt":0.3139871846708063,"score_spread":0.29609616522008786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080845586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98555154,0.0002921581,0.003093785,0.003164877,0.0012519142,0.0005808214,0.000032358643,0.00012442263,0.0059081046],"genre_scores_gemma":[0.9888961,0.000059283848,0.00023885237,0.009481284,0.00019968819,0.00010722246,0.000012187046,0.000041297993,0.0009641152],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982069,0.00036227764,0.00028256225,0.0005246516,0.00013875964,0.00048481266],"domain_scores_gemma":[0.9990951,0.000109882014,0.00007673028,0.00020084741,0.000082042054,0.00043543923],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028694607,0.00026499873,0.00039308443,0.00018030869,0.00017111386,0.0000536271,0.00016079034,0.00017922018,0.0008408353],"category_scores_gemma":[0.000080095175,0.00028057536,0.00007011675,0.00016503419,0.00013107504,0.00010883226,0.0001735292,0.00025876454,0.00019352516],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005286663,0.00011585383,0.0021936425,0.000039162973,0.00025235367,0.00067749596,0.0006736848,0.00001390241,0.9143993,0.00047345387,0.0333544,0.047278054],"study_design_scores_gemma":[0.005243331,0.0024149437,0.0061451118,0.000019941172,0.00025125963,0.0008210778,0.0001295982,0.0020637014,0.043669224,0.000087145934,0.9384752,0.000679472],"about_ca_topic_score_codex":0.00023217294,"about_ca_topic_score_gemma":0.000061269464,"teacher_disagreement_score":0.9051208,"about_ca_system_score_codex":0.00006018331,"about_ca_system_score_gemma":0.000037874728,"threshold_uncertainty_score":0.99996465},"labels":[],"label_agreement":null},{"id":"W2088535435","doi":"10.1124/mol.104.008953","title":"The Effect of Hydroxylamine on KATP Channels in Vascular Smooth Muscle and Underlying Mechanisms","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Biophysics; Chemistry; Superoxide; Hydroxylamine; Xanthine oxidase; Vascular smooth muscle; Membrane potential; Nitric oxide; Patch clamp; Hypoxanthine; Biochemistry; Endocrinology; Biology; Enzyme","score_opus":0.009983500027283869,"score_gpt":0.29473192846008534,"score_spread":0.28474842843280146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088535435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99495316,0.0015529748,0.00081776496,0.0011233211,0.00020983095,0.00066810934,8.190928e-7,0.000027057373,0.0006469866],"genre_scores_gemma":[0.9983677,0.00017567037,0.00015225097,0.0010799889,0.00007247253,0.00006710416,0.000002678227,0.000027541428,0.00005456625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987901,0.0002863059,0.00020829774,0.00023180831,0.00017553206,0.00030797545],"domain_scores_gemma":[0.9992647,0.00039488275,0.000058295598,0.0001800487,0.000018019498,0.000084042375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006568199,0.0001613226,0.00032881502,0.00014315754,0.00005431067,0.0000060173165,0.000089991605,0.00009086432,0.000034715966],"category_scores_gemma":[0.00006988821,0.00011192355,0.00008961733,0.00017970022,0.00007511866,0.000023750228,0.000047701084,0.00023120879,0.000015744994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028432804,0.00007653471,0.000087812274,0.000084309715,0.00010010276,0.00017723627,0.000067926005,0.0007301147,0.9627606,0.000334224,0.000090193884,0.03520657],"study_design_scores_gemma":[0.00854425,0.0023766027,0.001602334,0.00006419843,0.0002568478,0.000019962432,0.00001811621,0.007367827,0.9753048,0.00044777154,0.0038466859,0.00015063117],"about_ca_topic_score_codex":0.000019767722,"about_ca_topic_score_gemma":0.0000027573906,"teacher_disagreement_score":0.035055943,"about_ca_system_score_codex":0.000049299993,"about_ca_system_score_gemma":0.000019289597,"threshold_uncertainty_score":0.456411},"labels":[],"label_agreement":null},{"id":"W2088798421","doi":"10.1124/mol.63.2.456","title":"In Vivo Evidence for Dopamine-Mediated Internalization of D2-Receptors after Amphetamine: Differential Findings with [3H]Raclopride versus [3H]Spiperone","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Raclopride; Amphetamine; Spiperone; Chemistry; Dopamine; Agonist; Dopamine receptor; Receptor; Dopamine receptor D2; Striatum; Internal medicine; Endocrinology; Internalization; Biology; Biochemistry; Medicine","score_opus":0.03302649618802759,"score_gpt":0.3301631024640198,"score_spread":0.2971366062759922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088798421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866749,0.00006116028,0.010111061,0.0001778835,0.0016501362,0.0012067846,0.000032965432,0.000049291608,0.00003579828],"genre_scores_gemma":[0.99771005,0.000052273484,0.00035058113,0.0010199624,0.0000380842,0.0006250627,0.000004506808,0.00006822895,0.00013122753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99730104,0.00039705308,0.00055172073,0.00076874887,0.0004043683,0.0005770771],"domain_scores_gemma":[0.9988523,0.0004512888,0.00019989425,0.00025613245,0.000099949946,0.00014041945],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016638827,0.00035405194,0.0004062308,0.00033350367,0.000048016173,0.000030421887,0.00044569315,0.00012733461,0.0017390923],"category_scores_gemma":[0.00039071057,0.0003390529,0.00011808745,0.0005891132,0.000315614,0.0003743889,0.00005937792,0.00026574687,0.000028667084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023844098,0.00026975974,0.0036390317,0.000067738096,0.000016792987,0.00018621501,0.00016708205,0.00011047947,0.99278927,0.00008709653,0.00017707687,0.00010507314],"study_design_scores_gemma":[0.005318891,0.0006556522,0.00050343684,0.00006562719,0.000120480974,0.000027764085,0.000009069045,0.00015637054,0.99062926,0.000010698136,0.0021809854,0.00032176002],"about_ca_topic_score_codex":0.000021465043,"about_ca_topic_score_gemma":0.000014884921,"teacher_disagreement_score":0.011035154,"about_ca_system_score_codex":0.00012974342,"about_ca_system_score_gemma":0.00008493849,"threshold_uncertainty_score":0.9999061},"labels":[],"label_agreement":null},{"id":"W2090527768","doi":"10.1124/mol.114.096222","title":"Identification and Characterization of a Selective Allosteric Antagonist of Human P2X4 Receptor Channels","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Homomeric; Allosteric regulation; Antagonist; Pharmacology; Extracellular; Chemistry; Purinergic receptor; Receptor; Biophysics; Patch clamp; In vitro; Biochemistry; Biology","score_opus":0.014772592656981741,"score_gpt":0.29063578681794366,"score_spread":0.27586319416096194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090527768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960371,0.0005221,0.0028528043,0.00010911422,0.00017569459,0.00018029765,0.000016913738,0.0000054972243,0.00010046352],"genre_scores_gemma":[0.9992275,0.000052014653,0.000073563024,0.00011824552,0.00010877003,0.000020384692,0.00024290646,0.000014686352,0.00014188736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992539,0.00010866083,0.0002389389,0.00020622942,0.00007910044,0.00011312106],"domain_scores_gemma":[0.9994458,0.0000038230846,0.000200957,0.00010054615,0.00019217722,0.00005672701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014978576,0.000095711046,0.00015220251,0.00005958719,0.00002699714,0.0000055015616,0.000090792564,0.00009097602,0.000013876601],"category_scores_gemma":[0.00001531954,0.000103365855,0.000034838977,0.000103611696,0.00009048665,0.0000051439283,0.00006908663,0.000044548244,0.0000013841469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096612486,0.00006742133,0.00036545927,0.000027082238,0.00007235676,0.0000021747842,0.00014125596,0.000020893562,0.9974031,0.000050391376,0.0016560433,0.000097223514],"study_design_scores_gemma":[0.00068826845,0.00038534743,0.0003655992,0.0000049899113,0.000046025514,0.000010397686,0.00002933201,0.00006871536,0.9966994,0.000033317578,0.001575361,0.00009324957],"about_ca_topic_score_codex":0.000009555015,"about_ca_topic_score_gemma":2.0911807e-7,"teacher_disagreement_score":0.003190427,"about_ca_system_score_codex":0.00000828011,"about_ca_system_score_gemma":0.00004415806,"threshold_uncertainty_score":0.42151374},"labels":[],"label_agreement":null},{"id":"W2094312018","doi":"10.1124/mol.107.039511","title":"Effect of Cathepsin K Inhibitor Basicity on in Vivo Off-Target Activities","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Cathepsin; Cathepsin B; Cathepsin O; In vivo; Chemistry; Cathepsin H; Cysteine protease; Biochemistry; Benzamide; Cathepsin L; Cathepsin A; Cysteine; Pharmacology; Enzyme; Enzyme inhibitor; Stereochemistry; Biology","score_opus":0.0036067497461800915,"score_gpt":0.27689324066056,"score_spread":0.2732864909143799,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094312018","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99534285,0.0016016528,0.00036870103,0.000055489458,0.0004066284,0.0002976758,0.000039234314,0.000011590696,0.0018761776],"genre_scores_gemma":[0.9987182,0.000056769,0.00009562105,0.00076337054,0.00018449573,0.0000279696,0.000023582283,0.000025156398,0.00010481078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998656,0.00029276902,0.00023833515,0.00033125456,0.00013490597,0.0003467347],"domain_scores_gemma":[0.99950397,0.00007250172,0.000087395805,0.00020912898,0.000027168415,0.00009982388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005332336,0.0002007739,0.0002827155,0.00013391652,0.000028076192,0.00000439352,0.00015677232,0.00016025003,0.00008748477],"category_scores_gemma":[0.00007116557,0.00018867865,0.00013830517,0.00012565916,0.00013205854,0.000003696561,0.00008801893,0.00012012892,0.000004446793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015766717,0.00025854944,0.0022854614,0.000045445133,0.00004649159,0.00007475105,0.000024211487,0.00009407685,0.99125654,0.00006480668,0.0017679416,0.002505049],"study_design_scores_gemma":[0.0018589823,0.00089940196,0.0013346687,0.00000766846,0.000046950387,0.000005222396,0.000012041534,0.000015444024,0.98404205,0.000019936107,0.011594764,0.00016284849],"about_ca_topic_score_codex":0.000023999253,"about_ca_topic_score_gemma":0.0000124897715,"teacher_disagreement_score":0.009826822,"about_ca_system_score_codex":0.000016569844,"about_ca_system_score_gemma":0.000054805176,"threshold_uncertainty_score":0.7694092},"labels":[],"label_agreement":null},{"id":"W2094792084","doi":"10.1124/mol.105.017970","title":"Interaction of d-Tubocurarine with Potassium Channels: Molecular Modeling and Ligand Binding","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Binding site; Biophysics; Potassium channel; BK channel; Calcium-activated potassium channel; Homology modeling; Crystallography; Stereochemistry; Biochemistry; Biology","score_opus":0.01003844949189413,"score_gpt":0.2578019683953479,"score_spread":0.24776351890345377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094792084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94016683,0.000353735,0.05802746,0.0002312314,0.00046787751,0.00018582224,0.000004869363,0.00001719703,0.00054497126],"genre_scores_gemma":[0.9987402,0.00003602011,0.00039357616,0.00019430688,0.00025284494,0.000025235608,0.00016201116,0.000028896138,0.0001668972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999063,0.00006728495,0.00022430225,0.0003240355,0.00011640035,0.0002049731],"domain_scores_gemma":[0.999587,0.000007455661,0.00011031897,0.00011964207,0.00012043382,0.000055145778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010991208,0.00016651592,0.00016332405,0.00013118632,0.000057666995,0.000015929998,0.00006947405,0.00012765027,0.000016871914],"category_scores_gemma":[0.000010778715,0.0001579756,0.000054459193,0.00012646617,0.00006970949,0.000009486389,0.000066385495,0.00009698453,0.000002122556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022394095,0.000059057886,0.00023430084,0.000023063802,0.0000675134,0.000018011973,0.000014877082,0.05775502,0.9409339,0.00017384534,0.00020485888,0.00029162742],"study_design_scores_gemma":[0.0011986943,0.00029577262,0.000043607415,0.0000099331055,0.00006333822,0.000079107565,0.000035473742,0.03639496,0.9599092,0.00007983106,0.0017131959,0.00017688093],"about_ca_topic_score_codex":0.00003464309,"about_ca_topic_score_gemma":0.000003096891,"teacher_disagreement_score":0.058573376,"about_ca_system_score_codex":0.000014949388,"about_ca_system_score_gemma":0.000029120572,"threshold_uncertainty_score":0.6442058},"labels":[],"label_agreement":null},{"id":"W2095714705","doi":"10.1124/mol.64.2.395","title":"Desensitization of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Facilitates Use-Dependent Inhibition by Pentobarbital","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"AMPA receptor; Kainate receptor; Chemistry; Desensitization (medicine); Excitatory postsynaptic potential; Biophysics; Postsynaptic potential; Agonist; Pentobarbital; Glutamate receptor; Pharmacology; Receptor; Biochemistry; Biology","score_opus":0.03126240519823908,"score_gpt":0.31184675451070726,"score_spread":0.2805843493124682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095714705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956723,0.00016919282,0.0010689507,0.00038219264,0.0012514512,0.00081974117,0.00006484856,0.000118305965,0.0004530547],"genre_scores_gemma":[0.99627686,0.00031696554,0.00005542688,0.0025622316,0.000025008503,0.00008435869,0.000010226422,0.000052172054,0.0006167702],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99487996,0.0019685025,0.0005461893,0.001039921,0.00071874354,0.000846671],"domain_scores_gemma":[0.9986397,0.0004115637,0.0002283659,0.00030113215,0.00015259934,0.00026661545],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004972772,0.00034074963,0.00037532268,0.00036781892,0.00027222902,0.0000618753,0.00036157004,0.00017277423,0.0006172807],"category_scores_gemma":[0.00092949456,0.00035051562,0.00014960863,0.0009134979,0.0007548218,0.00051341334,0.00017458228,0.0005609292,0.00019314406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102602324,0.00039139538,0.0004256491,0.0000290125,0.000013679592,0.00033500663,0.000091313224,0.00017038315,0.99567735,0.00035716282,0.0021376594,0.00026878336],"study_design_scores_gemma":[0.0014501075,0.000442454,0.000052373372,0.0000061901255,0.000044244047,0.00014367347,0.0000318723,0.00035572887,0.99247897,0.00018294429,0.0045238854,0.00028754768],"about_ca_topic_score_codex":0.000015136777,"about_ca_topic_score_gemma":0.0000012088689,"teacher_disagreement_score":0.0037597509,"about_ca_system_score_codex":0.00010802286,"about_ca_system_score_gemma":0.0001579268,"threshold_uncertainty_score":0.9998947},"labels":[],"label_agreement":null},{"id":"W2095886291","doi":"10.1124/mol.111.071787","title":"In Vivo and In Vitro Characterization of a First-in-Class Novel Azole Analog That Targets Pregnane X Receptor Activation","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Theratechnologies (Canada)","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Damon Runyon Cancer Research Foundation","keywords":"Pregnane X receptor; Constitutive androstane receptor; Pharmacology; In vivo; Chemistry; Nuclear receptor; Receptor; Biology; Biochemistry; Transcription factor","score_opus":0.06212254743634515,"score_gpt":0.3450595616488686,"score_spread":0.28293701421252343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095886291","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955706,0.0005203972,0.00036022218,0.0006401869,0.0009863683,0.0008548886,0.000097565346,0.0000214728,0.00094827934],"genre_scores_gemma":[0.9960152,0.0010567055,0.00032937343,0.0021575391,0.00007010934,0.00020783256,0.00004855529,0.0000385411,0.00007617794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976507,0.0004923748,0.0006107974,0.0005069068,0.00015015103,0.0005891085],"domain_scores_gemma":[0.9992423,0.00011989766,0.00028148002,0.00014698693,0.00006686761,0.0001424693],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006506425,0.0003097859,0.00052122166,0.00066945254,0.000049075876,0.0000061961537,0.000270637,0.00038894932,0.0014999643],"category_scores_gemma":[0.000032689404,0.00034978945,0.000067664354,0.00055100716,0.00018528938,0.00022492358,0.00014619218,0.0006484665,0.000010521283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015697515,0.001135927,0.009945488,0.00009101,0.000074043775,0.0000764958,0.0015370653,0.00018038496,0.98392123,0.00012649459,0.0001034877,0.0012386353],"study_design_scores_gemma":[0.005723735,0.000058442787,0.012829325,0.000023691484,0.000067244924,0.000008112195,0.000035243822,0.004928644,0.9618957,0.00014866193,0.013987257,0.00029394604],"about_ca_topic_score_codex":0.00010015898,"about_ca_topic_score_gemma":0.000036522342,"teacher_disagreement_score":0.02202552,"about_ca_system_score_codex":0.00009519476,"about_ca_system_score_gemma":0.00006993173,"threshold_uncertainty_score":0.9998954},"labels":[],"label_agreement":null},{"id":"W2096783657","doi":"10.1124/mol.106.033761","title":"Adrenomedullin Stimulates Nitric Oxide Production from Primary Rat Hypothalamic Neurons: Roles of Calcium and Phosphatases","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nitric oxide; Okadaic acid; Chemistry; Dephosphorylation; Chelerythrine; Endocrinology; Phosphatase; Internal medicine; Calcineurin; Calcium; Nitric oxide synthase; Adrenomedullin; Protein kinase C; Phosphorylation; Biochemistry; Biology; Receptor; Transplantation","score_opus":0.021630289061931717,"score_gpt":0.2786048729655489,"score_spread":0.2569745839036172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096783657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974404,0.0014245707,0.000100495796,0.00011754521,0.0003706997,0.00033999403,0.000040069368,0.000063377396,0.000102864484],"genre_scores_gemma":[0.99686325,0.00026180473,0.00020389716,0.0024341862,0.00012197266,0.000010666564,0.000017836179,0.00003549811,0.00005086562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982237,0.0002188344,0.00035732173,0.0006551933,0.0001497536,0.00039516238],"domain_scores_gemma":[0.9991201,0.00036595858,0.0001786332,0.00018645207,0.000041372776,0.00010747822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012163018,0.00021997884,0.00031914242,0.00015999515,0.00008472473,0.000011842615,0.0002301365,0.000072048715,0.00006479901],"category_scores_gemma":[0.00015792178,0.00021215215,0.0000674024,0.0002842384,0.0003512322,0.000112020774,0.00018737247,0.00023426319,0.000021731903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003250289,0.00018963308,0.00040669317,0.000029631245,0.000013578076,0.00030607704,0.000018700928,0.0003710339,0.99525535,0.00007748945,0.0003406904,0.0026660988],"study_design_scores_gemma":[0.0006513333,0.00016067277,0.015987886,0.000007494294,0.00006838409,0.000048356233,0.00000940371,0.00009543084,0.9811396,0.0004294276,0.0012267368,0.0001752638],"about_ca_topic_score_codex":0.00003810498,"about_ca_topic_score_gemma":0.0000016033206,"teacher_disagreement_score":0.015581193,"about_ca_system_score_codex":0.000022006952,"about_ca_system_score_gemma":0.000034100965,"threshold_uncertainty_score":0.8651314},"labels":[],"label_agreement":null},{"id":"W2097263737","doi":"10.1124/mol.111.071779","title":"Orientation of μ-Conotoxin PIIIA in a Sodium Channel Vestibule, Based on Voltage Dependence of Its Binding","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Sodium channel; Orientation (vector space); Vestibule; Chemistry; Biophysics; Conotoxin; Sodium; Neuroscience; Geometry; Biology; Mathematics; Biochemistry; Peptide","score_opus":0.02205956749258479,"score_gpt":0.27447194063416175,"score_spread":0.25241237314157694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097263737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98160243,0.00007371979,0.016424164,0.00003507055,0.0006196453,0.00029988002,0.000016541571,0.0000076228307,0.0009209202],"genre_scores_gemma":[0.9992443,0.000017269404,0.00016867454,0.0002876894,0.000054568,0.000040822175,0.000085351596,0.000016097087,0.0000852581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905586,0.00010208093,0.00028096494,0.0002676876,0.00011722373,0.0001761744],"domain_scores_gemma":[0.99952084,0.000014902794,0.00017313301,0.00013343804,0.00010869579,0.000048965598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020698612,0.00012219032,0.00015244517,0.00020810305,0.000021069774,0.0000018483398,0.00011995527,0.00014731991,0.00011285397],"category_scores_gemma":[0.0000661893,0.00013295442,0.000061042585,0.00018752413,0.00006063318,0.0000055486307,0.000037618753,0.0000806589,0.000007144103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005018651,0.00019172014,0.00088453846,0.000040663923,0.00002012005,0.000011799048,0.00010085344,0.002280312,0.9954712,0.0001372729,0.00008731326,0.00027239017],"study_design_scores_gemma":[0.0014574458,0.0005198112,0.0028571552,0.000014546922,0.000018032464,0.0000028858783,0.00003285757,0.0092072785,0.98557174,0.000032814507,0.00017306254,0.00011234536],"about_ca_topic_score_codex":0.000014920172,"about_ca_topic_score_gemma":0.0000035139049,"teacher_disagreement_score":0.017641835,"about_ca_system_score_codex":0.000018020322,"about_ca_system_score_gemma":0.00006728077,"threshold_uncertainty_score":0.5421724},"labels":[],"label_agreement":null},{"id":"W2097532953","doi":"10.1124/mol.105.016576","title":"Analysis of Human Multidrug Resistance Protein 1 (ABCC1) by Matrix-Assisted Laser Desorption Ionization/Time of Flight Mass Spectrometry: Toward Identification of Leukotriene C4 Binding Sites","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Queen's University","funders":"","keywords":"ATP-binding cassette transporter; Mass spectrometry; Chemistry; Transmembrane protein; Biochemistry; Biophysics; Chromatography; Biology; Transporter","score_opus":0.009742698938072924,"score_gpt":0.2893854611259856,"score_spread":0.2796427621879127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097532953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96944255,0.0006116199,0.028633716,0.00036989382,0.000044481923,0.0006405436,0.00012256387,0.00003907433,0.00009558198],"genre_scores_gemma":[0.99156314,0.00004320731,0.004948646,0.00003330354,0.000030180907,0.00003828566,0.0008264507,0.000031012536,0.0024857917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99790734,0.00013479487,0.00093185354,0.00036384718,0.0004203794,0.00024176812],"domain_scores_gemma":[0.99857146,0.000026367536,0.0007057507,0.00027490273,0.00033593035,0.0000855961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040627347,0.00019339,0.00069810066,0.0008982173,0.000056129666,0.0000059568956,0.00017016074,0.00015135841,0.00055734906],"category_scores_gemma":[0.00002732747,0.00019301669,0.00026521605,0.0020703457,0.00013177536,0.00008519232,0.000016710492,0.0001290085,0.000008429247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003416267,0.0004510016,0.0011844763,0.00029470725,0.0011066326,0.00001667751,0.0001955555,0.00041946498,0.9956186,0.00016207254,0.00014608732,0.00006310389],"study_design_scores_gemma":[0.0018579517,0.00010195309,0.0030684748,0.00005018123,0.002709882,0.0000011113029,0.00005134484,0.001768047,0.990086,0.000026483365,0.00013274854,0.00014582028],"about_ca_topic_score_codex":0.0000084313815,"about_ca_topic_score_gemma":0.00001437769,"teacher_disagreement_score":0.02368507,"about_ca_system_score_codex":0.00013610632,"about_ca_system_score_gemma":0.0000581689,"threshold_uncertainty_score":0.78709924},"labels":[],"label_agreement":null},{"id":"W2098008929","doi":"10.1124/mol.106.031732","title":"Identification of a Second Blocker Binding Site at the Cytoplasmic Mouth of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Cystic fibrosis transmembrane conductance regulator; Chloride channel; Regulator; Cytoplasm; Binding site; Identification (biology); Biophysics; Transmembrane protein; Chemistry; Biochemistry; Biology; Receptor; Gene","score_opus":0.010372568421093749,"score_gpt":0.2951664673206615,"score_spread":0.28479389889956774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098008929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99515545,0.0011772794,0.00092166744,0.0011000154,0.00036768956,0.000992545,0.00017338227,0.000019490066,0.00009248139],"genre_scores_gemma":[0.99799967,0.000030505793,0.00017120343,0.00024745017,0.00006394742,0.000041102918,0.00004168664,0.000032746786,0.0013717024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99798524,0.00014105067,0.00061673846,0.00033651732,0.0004964195,0.00042402386],"domain_scores_gemma":[0.998558,0.00031085816,0.00035331733,0.00045251087,0.0002117458,0.000113578906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007718035,0.00018364009,0.00037802148,0.00015196111,0.00012338809,0.000006233938,0.00029252507,0.00010027427,0.00038843334],"category_scores_gemma":[0.00017170806,0.00012235444,0.00019373054,0.0005714836,0.0005884148,0.000055521316,0.00010442077,0.0002788415,0.000018423789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012384589,0.000082814535,0.00025095907,0.00036463776,0.00015575807,0.00004459474,0.00044025434,0.00021397883,0.99650717,0.000022758666,0.0004886802,0.00018993889],"study_design_scores_gemma":[0.0018476835,0.000117676456,0.006833982,0.00007547636,0.0002574435,0.00015220208,0.000103408966,0.0007694122,0.9886011,0.00004381664,0.0010964175,0.00010138641],"about_ca_topic_score_codex":0.000011208919,"about_ca_topic_score_gemma":0.00003293335,"teacher_disagreement_score":0.007906072,"about_ca_system_score_codex":0.00013973004,"about_ca_system_score_gemma":0.00011506283,"threshold_uncertainty_score":0.49894693},"labels":[],"label_agreement":null},{"id":"W2098134263","doi":"10.1124/mol.59.6.1446","title":"Key Structural Features of Prostaglandin E<sub>2</sub>and Prostanoid Analogs Involved in Binding and Activation of the Human EP<sub>1</sub>Prostanoid Receptor","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Prostanoid; Agonist; Potency; Chemistry; Receptor; Radioligand; Prostaglandin; Stereochemistry; Partial agonist; Biochemistry; In vitro","score_opus":0.008075821480597819,"score_gpt":0.26265800810132467,"score_spread":0.25458218662072685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098134263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974098,0.00044335437,0.000013036882,0.00030573568,0.00025581472,0.0014916216,0.000015474257,0.00002211228,0.000043056833],"genre_scores_gemma":[0.9993295,0.00012789926,0.000035273442,0.0002570581,0.000091353315,0.0000656976,0.000047297362,0.000035097535,0.000010789773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982717,0.00029199768,0.0004339926,0.00035623362,0.00027854415,0.00036752518],"domain_scores_gemma":[0.9991881,0.0000811353,0.0003050086,0.00018753098,0.000115136456,0.00012306675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039712383,0.00025868448,0.0004928131,0.0002983677,0.00011204752,0.000011070907,0.00009972931,0.00022063713,0.000011052365],"category_scores_gemma":[0.00010526251,0.00019960287,0.000080021084,0.00042732625,0.00032002595,0.00009400649,0.00010500112,0.0004243645,8.4355815e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005631648,0.000058227935,0.100458905,0.0003410799,0.00008132823,0.00005753407,0.00073595985,0.0000076084802,0.89626354,0.00013925045,0.00018116948,0.0011122319],"study_design_scores_gemma":[0.0036917592,0.00033921064,0.11176926,0.000114835275,0.000106637104,0.000039795745,0.00009203532,0.00006818972,0.88345385,0.00010188539,0.000064893095,0.0001576484],"about_ca_topic_score_codex":0.000019291843,"about_ca_topic_score_gemma":0.0000305839,"teacher_disagreement_score":0.012809692,"about_ca_system_score_codex":0.00010803028,"about_ca_system_score_gemma":0.00010279468,"threshold_uncertainty_score":0.81395686},"labels":[],"label_agreement":null},{"id":"W2098180946","doi":"10.1124/mol.59.4.716","title":"Cell-Specific Regulation of Human Aryl Hydrocarbon Receptor Expression by Transforming Growth Factor-β<sub>1</sub>","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"SMAD; Aryl hydrocarbon receptor; Transfection; A549 cell; Molecular biology; Cell biology; Biology; Chemistry; Transforming growth factor; Cell; Gene; Biochemistry; Transcription factor","score_opus":0.008351494708319822,"score_gpt":0.24825013745451985,"score_spread":0.2398986427462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098180946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905913,0.0035816273,0.0047537573,0.000047141857,0.00022955029,0.00035635952,0.000034956203,0.000041933305,0.00036337983],"genre_scores_gemma":[0.9984273,0.00034661873,0.0001364054,0.00017259002,0.00017777833,0.000056796256,0.00056468445,0.000066000066,0.000051841955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982702,0.00014226274,0.00042230843,0.0005434908,0.00023319379,0.0003885426],"domain_scores_gemma":[0.9992471,0.00001692378,0.00019869854,0.0002780592,0.0001042563,0.00015498202],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011080068,0.0002840119,0.00025609817,0.00010501382,0.00012125433,0.000012214759,0.0002916614,0.00027608252,0.00012410336],"category_scores_gemma":[0.00001115041,0.00031266978,0.00016943386,0.00014547679,0.0001295621,0.000010878525,0.000075855634,0.00015065326,0.000011721317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021175943,0.00026804325,0.00045069886,0.000045263205,0.00005061771,0.000011756971,0.00006649372,0.000096259086,0.9880487,0.000008194352,0.010110468,0.00063176506],"study_design_scores_gemma":[0.0013041873,0.0002724816,0.0002839208,0.000017838045,0.000043618144,0.000006444334,0.000014638572,0.000026800764,0.98980695,0.00004164828,0.007870478,0.00031100828],"about_ca_topic_score_codex":0.0000042213846,"about_ca_topic_score_gemma":4.7506296e-7,"teacher_disagreement_score":0.007835991,"about_ca_system_score_codex":0.00003576182,"about_ca_system_score_gemma":0.00004928763,"threshold_uncertainty_score":0.9999325},"labels":[],"label_agreement":null},{"id":"W2098218026","doi":"10.1124/mol.114.096016","title":"Potent Trypanocidal Curcumin Analogs Bearing a Monoenone Linker Motif Act on Trypanosoma brucei by Forming an Adduct with Trypanothione","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"Linker; Curcumin; Antiparasitic; Glutathione; Trypanosoma brucei; Biochemistry; Stereochemistry; Chemistry; In vitro; Mechanism of action; Antiparasitic agent; Trypanosoma; Adduct; Biology; Enzyme; Pharmacology","score_opus":0.013027257862465858,"score_gpt":0.3078928356666946,"score_spread":0.2948655778042288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098218026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97033125,0.00024707097,0.017373618,0.0051285415,0.00017834957,0.0011475788,0.000054184296,0.00023629611,0.005303117],"genre_scores_gemma":[0.99098617,0.0000464995,0.0022695153,0.0046999333,0.0004036383,0.00024878286,0.00029316696,0.00012640381,0.0009258694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99627846,0.00031553156,0.0005132168,0.0009548612,0.00070680014,0.0012311118],"domain_scores_gemma":[0.99771976,0.0001325825,0.00018159613,0.0007880076,0.00023992099,0.0009381228],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006345592,0.00048207352,0.00067547517,0.0003988537,0.00032415317,0.000070502385,0.0004192172,0.0002808598,0.00046446748],"category_scores_gemma":[0.00013539738,0.00041477938,0.00019889387,0.0005784985,0.00028184714,0.00022784735,0.00012709122,0.0009334347,0.00016453105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009163775,0.0009160405,0.00040547302,0.000050511684,0.0003238865,0.000190411,0.00015894903,0.00011868384,0.9616149,0.0003900786,0.0047787405,0.030135967],"study_design_scores_gemma":[0.0110394815,0.006916858,0.068375796,0.000079904195,0.00044581186,0.0007250327,0.00015973531,0.005142253,0.8495468,0.00016364126,0.056636855,0.0007678172],"about_ca_topic_score_codex":0.00013845283,"about_ca_topic_score_gemma":0.000014738147,"teacher_disagreement_score":0.11206807,"about_ca_system_score_codex":0.00026153575,"about_ca_system_score_gemma":0.0002596115,"threshold_uncertainty_score":0.9998304},"labels":[],"label_agreement":null},{"id":"W2098281388","doi":"10.1124/mol.104.007708","title":"Functional Interactions Between Nucleotide Binding Domains and Leukotriene C4 Binding Sites of Multidrug Resistance Protein 1 (ABCC1)","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"Cyclic nucleotide-binding domain; Nucleotide; Binding site; ATP-binding cassette transporter; Adenosine triphosphate; Chemistry; Biochemistry; Walker motifs; ATP hydrolysis; Stereochemistry; ATPase; Biology; Transporter; Enzyme; Gene","score_opus":0.01846837358564317,"score_gpt":0.29064417170518725,"score_spread":0.27217579811954407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098281388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915244,0.00034643104,0.0038182545,0.002260799,0.00018847067,0.00056156126,0.000046203553,0.00006992871,0.0011839403],"genre_scores_gemma":[0.98887616,0.000032960103,0.007350359,0.00022001026,0.00024365346,0.000053146574,0.00009897845,0.000033171153,0.0030915732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858713,0.00006787283,0.00039942854,0.00035603752,0.00025844094,0.0003310859],"domain_scores_gemma":[0.9993585,0.00006442741,0.0001592445,0.00014681685,0.00010108172,0.00016995726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023502165,0.00020018694,0.0003844188,0.00029207848,0.00014855094,0.000009481806,0.00008322241,0.00010344076,0.00036824556],"category_scores_gemma":[0.000019278576,0.00019264848,0.00012088251,0.00026980872,0.00015594752,0.00011516054,0.000036140078,0.00034064954,0.000031905805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030583376,0.00013414069,0.0028528892,0.00012697607,0.00022376263,0.000113708506,0.00014047095,0.000031146792,0.9944115,0.00050210557,0.0006098627,0.00054756104],"study_design_scores_gemma":[0.002809646,0.000078437384,0.0045010597,0.00011607222,0.00034993526,0.000019949193,0.00009717764,0.000101923346,0.9765747,0.00006144172,0.015106405,0.00018323908],"about_ca_topic_score_codex":0.000006842329,"about_ca_topic_score_gemma":0.000032474727,"teacher_disagreement_score":0.017836828,"about_ca_system_score_codex":0.00011046665,"about_ca_system_score_gemma":0.00007954893,"threshold_uncertainty_score":0.78559774},"labels":[],"label_agreement":null},{"id":"W2099754996","doi":"10.1124/mol.112.079152","title":"Molecular Mechanisms of Chloroquine Inhibition of Heterologously Expressed Kir6.2/SUR2A Channels","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Michael Smith Health Research BC; Consejo Nacional de Ciencia y Tecnología; Heart and Stroke Foundation of Canada","keywords":"Chloroquine; Sulfonylurea receptor; Potassium channel; Biophysics; Kir6.2; Allosteric regulation; Inward-rectifier potassium ion channel; Chemistry; Protein subunit; Ion channel; Gating; Patch clamp; Cell biology; Pharmacology; Biology; Biochemistry; Receptor","score_opus":0.011383007836239542,"score_gpt":0.26182375059921037,"score_spread":0.25044074276297085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099754996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87482375,0.0005624311,0.12231328,0.00019167628,0.0014514811,0.0003189901,0.000024922072,0.000020012187,0.00029344915],"genre_scores_gemma":[0.99779725,0.00004735619,0.0005519218,0.00085164426,0.00031287692,0.0000632666,0.00026468444,0.00004122421,0.00006978047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984542,0.00021081323,0.0004243145,0.00030480378,0.00021472597,0.0003911493],"domain_scores_gemma":[0.99910444,0.000015097932,0.0002748717,0.0002669537,0.0002037234,0.00013489656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032105742,0.00022429368,0.00029845233,0.00015429073,0.000037792288,0.000004268581,0.00014154841,0.000289601,0.00015093324],"category_scores_gemma":[0.000049703543,0.00023771485,0.00019561163,0.00016686106,0.00012893252,0.000012697953,0.00013100624,0.000104250015,0.000008823696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025456253,0.00031751182,0.000063244195,0.00005029582,0.00013133061,0.0000065372515,0.00006242865,0.0024689545,0.99462,0.0010317713,0.00074054924,0.0002527765],"study_design_scores_gemma":[0.0013959507,0.0005076435,0.000111334506,0.000008045068,0.000075158205,0.000021285754,0.000029345556,0.00044993972,0.9943216,0.000337733,0.002545701,0.00019627724],"about_ca_topic_score_codex":0.000007390259,"about_ca_topic_score_gemma":2.9034422e-7,"teacher_disagreement_score":0.12297349,"about_ca_system_score_codex":0.000016301407,"about_ca_system_score_gemma":0.00003405301,"threshold_uncertainty_score":0.969373},"labels":[],"label_agreement":null},{"id":"W2100486135","doi":"10.1124/mol.112.083493","title":"Phosphodiesterase 4 Inhibitors Augment the Ability of Formoterol to Enhance Glucocorticoid-Dependent Gene Transcription in Human Airway Epithelial Cells: A Novel Mechanism for the Clinical Efficacy of Roflumilast in Severe Chronic Obstructive Pulmonary Disease","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Health Research Board","keywords":"Roflumilast; Formoterol; Medicine; Phosphodiesterase; COPD; Formoterol Fumarate; Exacerbation; Pharmacology; Glucocorticoid; Fluticasone propionate; Internal medicine; Asthma; Biology; Budesonide","score_opus":0.014134018966874952,"score_gpt":0.32086619091749885,"score_spread":0.3067321719506239,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2100486135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882859,0.00053759495,0.0047082235,0.0007997384,0.00044970412,0.0051173866,0.0000864282,0.000009546487,0.000005487097],"genre_scores_gemma":[0.9979977,0.000034710927,0.00008517528,0.0009750295,0.000114935945,0.0007385479,0.000011425216,0.000025313262,0.000017189272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978953,0.00023329444,0.00087145035,0.0004255469,0.00024562894,0.00032878917],"domain_scores_gemma":[0.9989004,0.00023766767,0.00020828962,0.00033822813,0.00014481149,0.0001705823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000380633,0.00021249765,0.0004396907,0.00008839771,0.000054771084,0.0000051156094,0.00021983041,0.000102476326,0.00008503135],"category_scores_gemma":[0.00006781262,0.00014085832,0.00028708592,0.00015234553,0.00021892317,0.00005476732,0.000084921674,0.0002538901,0.0000047482235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019084438,0.0016145785,0.0012368141,0.00022752937,0.0000761506,0.000032285956,0.00028955683,0.0013735188,0.98500234,0.000028113403,0.000021754244,0.008188932],"study_design_scores_gemma":[0.004508993,0.0008284661,0.10240078,0.000057955534,0.0002557608,0.0000036997685,0.0001606412,0.0018466796,0.8896225,0.00010980099,0.00007179115,0.00013290886],"about_ca_topic_score_codex":0.000110690984,"about_ca_topic_score_gemma":0.000022260108,"teacher_disagreement_score":0.10116396,"about_ca_system_score_codex":0.00019458674,"about_ca_system_score_gemma":0.0002604172,"threshold_uncertainty_score":0.5744036},"labels":[],"label_agreement":null},{"id":"W2101085046","doi":"10.1124/mol.108.053793","title":"Intracellular Potassium Stabilizes Human Ether-à-go-go-Related Gene Channels for Export from Endoplasmic Reticulum","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; Queen's University","keywords":"hERG; Endoplasmic reticulum; Potassium channel; Chemistry; Intracellular; Potassium channel blocker; Biophysics; Biochemistry; Biology","score_opus":0.01028789488036522,"score_gpt":0.2862609826620818,"score_spread":0.27597308778171653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101085046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98928356,0.0022275343,0.0013489776,0.003730571,0.0009817594,0.0013430652,0.00003905918,0.00018441939,0.0008610556],"genre_scores_gemma":[0.99255186,0.00008295799,0.00091667264,0.004294496,0.0007012093,0.0001669921,0.0005157813,0.00006218404,0.0007078478],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976059,0.00024938004,0.00051036384,0.0007128038,0.00018435415,0.00073720247],"domain_scores_gemma":[0.9989563,0.00010315038,0.0001733347,0.00038528512,0.00014297533,0.00023891624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002444761,0.00037283,0.0007616238,0.00015080866,0.0001756905,0.000012501403,0.00015745472,0.0004322033,0.0007895057],"category_scores_gemma":[0.000038835926,0.00036624982,0.0004253653,0.00019087076,0.00020013252,0.00005004912,0.000046377572,0.0005887464,0.00010429098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006007263,0.00029137664,0.000040350293,0.00001982172,0.0006280626,0.0020527698,0.0001862978,0.00022958078,0.9909379,0.0004949398,0.0037410525,0.00077715726],"study_design_scores_gemma":[0.005344187,0.0015216309,0.00057546154,0.000016693848,0.0009543019,0.0003358529,0.000021675418,0.0007953793,0.98108804,0.004144421,0.004855229,0.0003471367],"about_ca_topic_score_codex":0.00001096049,"about_ca_topic_score_gemma":7.3100125e-7,"teacher_disagreement_score":0.009849833,"about_ca_system_score_codex":0.00009178523,"about_ca_system_score_gemma":0.00012214042,"threshold_uncertainty_score":0.99987894},"labels":[],"label_agreement":null},{"id":"W2101884412","doi":"10.1124/mol.107.038216","title":"Regulation of Lysophosphatidic Acid Receptor Expression and Function in Human Synoviocytes: Implications for Rheumatoid Arthritis?","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; American Society for Pharmacology and Experimental Therapeutics","keywords":"Lysophosphatidic acid; Autotaxin; MAPK/ERK pathway; Cytokine; Receptor; Signal transduction; Protein kinase C; Biology; Cell biology; Endocrinology; Chemistry; Biochemistry; Immunology","score_opus":0.009662990931227947,"score_gpt":0.2835764553755763,"score_spread":0.27391346444434833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101884412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9302758,0.0067060017,0.062271845,0.0000699688,0.00020898329,0.00038850715,0.0000121323255,0.000010465127,0.000056287867],"genre_scores_gemma":[0.9970602,0.00059171976,0.0017266349,0.00021006344,0.00011057937,0.00008625954,0.00017813347,0.000021851574,0.000014564598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990175,0.0000548896,0.0003439148,0.0003045312,0.00005782809,0.00022135675],"domain_scores_gemma":[0.9995241,0.000022928125,0.00014602272,0.00015077266,0.000092578455,0.00006355866],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043400744,0.00012102947,0.0001769893,0.000113882175,0.000079504585,0.0000064712513,0.00008552121,0.00015670147,0.00002409736],"category_scores_gemma":[0.000045624616,0.0001353829,0.00005829006,0.000111813875,0.00007161856,0.000007689391,0.00005001201,0.000062081555,5.878468e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021403433,0.00006326534,0.0013906625,0.000021740265,0.000021531518,4.1035779e-7,0.000040069302,0.000057450994,0.9925427,0.00077334506,0.00038342227,0.004491394],"study_design_scores_gemma":[0.002018126,0.00016391154,0.0101586105,0.000022742217,0.000013799114,0.0000056443478,0.000028345012,0.000020639878,0.9814825,0.00046836137,0.0054935096,0.0001238185],"about_ca_topic_score_codex":0.000007540704,"about_ca_topic_score_gemma":0.000006707459,"teacher_disagreement_score":0.06678438,"about_ca_system_score_codex":0.000012106399,"about_ca_system_score_gemma":0.000030772826,"threshold_uncertainty_score":0.55207545},"labels":[],"label_agreement":null},{"id":"W2102618044","doi":"10.1124/mol.107.039370","title":"Activation of Nuclear Factor (Erythroid-2 Like) Factor 2 by Toxic Bile Acids Provokes Adaptive Defense Responses to Enhance Cell Survival at the Emergence of Oxidative Stress","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Hospital for Sick Children","keywords":"GCLC; GCLM; Glutathione; Oxidative stress; Biology; Bile acid; Lithocholic acid; Biochemistry; Molecular biology; Enzyme","score_opus":0.012005333769107751,"score_gpt":0.2915825792239133,"score_spread":0.27957724545480556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102618044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897368,0.0006214848,0.007543699,0.00012304913,0.00025023642,0.0006843418,0.00069130975,0.000011085816,0.0003379973],"genre_scores_gemma":[0.99825954,0.00015067706,0.00064857426,0.00035362592,0.000074270836,0.000033566932,0.00009030291,0.000044125994,0.00034530208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99800426,0.00031100458,0.00044854745,0.0005732638,0.00023534504,0.00042758117],"domain_scores_gemma":[0.9986824,0.0001336007,0.0003620099,0.00039125976,0.00029043853,0.00014031043],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020576193,0.00029559832,0.00033464681,0.00007821939,0.00009727419,0.0000064311166,0.00045618002,0.00020074628,0.00023940514],"category_scores_gemma":[0.00009807291,0.00026089986,0.00015594534,0.00018122056,0.0003543271,0.0000104247265,0.00035584968,0.00016819153,0.000011801384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019311052,0.0002644135,0.00049083313,0.000037779682,0.00015173433,0.0000028807874,0.0006683765,0.00007954673,0.9930313,0.000007338511,0.0027554038,0.0005792718],"study_design_scores_gemma":[0.00046640888,0.000736122,0.0008330471,0.000011139838,0.00003597837,0.0000015830466,0.00054941984,0.00000795163,0.99286264,0.000011730167,0.0042232126,0.00026073906],"about_ca_topic_score_codex":0.00003676155,"about_ca_topic_score_gemma":0.000026385129,"teacher_disagreement_score":0.008522758,"about_ca_system_score_codex":0.000046320965,"about_ca_system_score_gemma":0.00007899858,"threshold_uncertainty_score":0.9999843},"labels":[],"label_agreement":null},{"id":"W2102656569","doi":"10.1124/mol.109.060251","title":"Ligand- and Heterodimer-Directed Signaling of the CB1 Cannabinoid Receptor","year":2009,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"G protein-coupled receptor; Functional selectivity; Receptor; Signal transduction; Cannabinoid; G protein; Ligand (biochemistry); Rhodopsin-like receptors; Cell biology; Chemistry; Cannabinoid receptor; Cell signaling; Biology; Biochemistry; Metabotropic receptor; Agonist","score_opus":0.025209222372950823,"score_gpt":0.3586875974592389,"score_spread":0.3334783750862881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102656569","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0051748375,0.9898569,0.000004449281,0.0022125072,0.00048855355,0.0018148997,0.000045000117,0.000055094457,0.00034773318],"genre_scores_gemma":[0.00039898697,0.99407464,0.0000660073,0.00088148867,0.00025502013,0.00018405356,0.000051989697,0.00008327878,0.0040045273],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972144,0.0005885914,0.0006725113,0.00057141215,0.0004232837,0.0005298026],"domain_scores_gemma":[0.99871016,0.00002638575,0.00033736683,0.00043800953,0.00023011184,0.00025798992],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038648388,0.00044853002,0.0017997947,0.00027818815,0.00010028867,0.0000182763,0.0003433739,0.0004412975,0.00026706824],"category_scores_gemma":[0.00009300737,0.00029788495,0.0006730781,0.00063660677,0.0003226278,0.000019906252,0.00022033839,0.0009967893,0.000014564156],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009037762,0.00023280883,0.0000042694637,0.011937632,0.0007465321,0.00019195538,0.00006436438,0.0000018234003,0.11986238,0.000022898143,0.11527199,0.75157297],"study_design_scores_gemma":[0.0007954226,0.00028643748,0.000012184491,0.0018634455,0.0018425783,0.0002593326,0.0000042393235,0.0000071708478,0.043136265,0.00000681533,0.95154196,0.00024416627],"about_ca_topic_score_codex":0.000043966505,"about_ca_topic_score_gemma":0.0000019095667,"teacher_disagreement_score":0.83627,"about_ca_system_score_codex":0.00015203976,"about_ca_system_score_gemma":0.0008976448,"threshold_uncertainty_score":0.9999473},"labels":[],"label_agreement":null},{"id":"W2102984985","doi":"10.1124/mol.107.037218","title":"Aryl Hydrocarbon Receptor Splice Variants in the Dioxin-Resistant Rat: Tissue Expression and Transactivational Activity","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Aryl hydrocarbon receptor; Transactivation; Biology; Exon; Molecular biology; Messenger RNA; Wild type; Gene expression; Mutant; Transcription factor; Gene; Biochemistry","score_opus":0.00856631135362514,"score_gpt":0.2865218839543672,"score_spread":0.27795557260074205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102984985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9854611,0.00054130005,0.012286207,0.000656352,0.00018239378,0.00041275605,0.000014285039,0.0000069688026,0.00043863204],"genre_scores_gemma":[0.9979818,0.000100694335,0.00039504824,0.0012328288,0.0001429224,0.0000461752,0.00003754948,0.000017651377,0.00004534578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987579,0.00015826398,0.00018456897,0.000399322,0.00018149024,0.00031847617],"domain_scores_gemma":[0.9995865,0.00004595096,0.00006719412,0.00019375951,0.000030186602,0.000076365926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055822666,0.00017413074,0.00015148935,0.00006555508,0.00009077733,0.000012754007,0.00017735388,0.00016198149,0.000052765205],"category_scores_gemma":[0.000013148913,0.0001478491,0.000051281135,0.00012947834,0.00008049215,0.0000060048765,0.0000620355,0.0001903289,0.0000024123192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005151338,0.00019117724,0.00014657612,0.000013193253,0.000030463114,0.00006779385,0.00011564658,0.000051591804,0.99651605,0.000036808713,0.00044208733,0.0018734856],"study_design_scores_gemma":[0.0010718632,0.00023373256,0.008937361,0.000005512429,0.000023914536,0.0000270421,0.000058449736,0.00004790698,0.9790704,0.000033598855,0.010319672,0.00017053311],"about_ca_topic_score_codex":0.000042223637,"about_ca_topic_score_gemma":0.000050662125,"teacher_disagreement_score":0.01744563,"about_ca_system_score_codex":0.000028884357,"about_ca_system_score_gemma":0.00005263192,"threshold_uncertainty_score":0.6029112},"labels":[],"label_agreement":null},{"id":"W2103897720","doi":"10.1124/mol.106.022897","title":"Simultaneous Activation of the δ Opioid Receptor (δOR)/Sensory Neuron-Specific Receptor-4 (SNSR-4) Hetero-Oligomer by the Mixed Bivalent Agonist Bovine Adrenal Medulla Peptide 22 Activates SNSR-4 but Inhibits δOR Signaling","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse","keywords":"Agonist; Receptor; Adenylyl cyclase; Cell biology; Chemistry; Signal transduction; G protein-coupled receptor; Functional selectivity; HEK 293 cells; Biochemistry; Biophysics; Biology","score_opus":0.007928825530473521,"score_gpt":0.2293944132220894,"score_spread":0.22146558769161587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103897720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992016,0.0016288616,0.0029308477,0.0007611718,0.0014033106,0.0008838849,0.00015101224,0.000042748394,0.00018215312],"genre_scores_gemma":[0.99558616,0.00031855653,0.0004915154,0.0010197646,0.00076414546,0.00010508856,0.0003961936,0.00012159192,0.0011969793],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962838,0.000775856,0.0007850517,0.0008850443,0.0005286959,0.00074151414],"domain_scores_gemma":[0.9982071,0.00019859977,0.00058124564,0.000579649,0.00029052625,0.00014288802],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000401525,0.0005709971,0.0004684524,0.00009976642,0.0004444609,0.00007094026,0.000754614,0.00037903746,0.00072938815],"category_scores_gemma":[0.00009944877,0.00043118795,0.0004138506,0.00030511353,0.0003715739,0.00001806764,0.00034329214,0.00052205735,0.00002585017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052648544,0.00025142016,0.00004680982,0.000040243398,0.00018621836,0.000009028342,0.00005315253,0.005050581,0.97407323,0.000053147534,0.018458923,0.0012507514],"study_design_scores_gemma":[0.0012035134,0.00039854093,0.00001938999,0.000034536813,0.000078285986,0.000028084456,0.00010249802,0.00029355384,0.9055065,0.00004250637,0.09186947,0.00042314644],"about_ca_topic_score_codex":0.00009777343,"about_ca_topic_score_gemma":0.000004907031,"teacher_disagreement_score":0.07341055,"about_ca_system_score_codex":0.00010234959,"about_ca_system_score_gemma":0.00012930854,"threshold_uncertainty_score":0.999814},"labels":[],"label_agreement":null},{"id":"W2103906226","doi":"10.1124/mol.64.5.1259","title":"Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Cloning (programming); Computational biology; Characterization (materials science); Biology; Molecular biology; Genetics; Computer science; Nanotechnology; Programming language; Materials science","score_opus":0.0070011487301090145,"score_gpt":0.24516866153142883,"score_spread":0.23816751280131981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103906226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956098,0.00020909033,0.0016517004,0.0015760334,0.00020131245,0.00031293274,0.0000015199313,0.0000104674955,0.00042715127],"genre_scores_gemma":[0.9981873,0.00010281862,0.00027426632,0.00082293287,0.000016881855,0.000012419554,0.000006131253,0.000010413909,0.00056685746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955297,0.00005222087,0.00010796486,0.00012244476,0.000060985338,0.00010340987],"domain_scores_gemma":[0.99979794,0.0000053181047,0.000045148998,0.000078050725,0.000028804607,0.000044762175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007853523,0.00006796463,0.00012910087,0.00003207061,0.000044034532,0.0000025039674,0.000024816007,0.000045230245,0.000045622426],"category_scores_gemma":[0.000005212198,0.00004693507,0.000027371028,0.00007791068,0.00008510464,0.000017193957,0.000011630211,0.00008463516,4.3086385e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032504973,0.000039200066,0.0012466264,0.00006102559,0.00002924691,0.00004036988,0.00011681411,3.450659e-7,0.99671954,0.0015120943,0.000019503728,0.00018275426],"study_design_scores_gemma":[0.0011033047,0.000059608185,0.007101739,0.000026861258,0.00015322762,0.00008726361,0.000011550943,0.00003129713,0.9833406,0.00014335998,0.0078920005,0.000049164548],"about_ca_topic_score_codex":9.1484094e-7,"about_ca_topic_score_gemma":7.3209424e-7,"teacher_disagreement_score":0.013378891,"about_ca_system_score_codex":0.000005797119,"about_ca_system_score_gemma":0.000025367839,"threshold_uncertainty_score":0.19139566},"labels":[],"label_agreement":null},{"id":"W2104551057","doi":"10.1124/mol.64.1.170","title":"Generation and Functional Characterization of Arylamine N-Acetyltransferase Nat1/Nat2Double-Knockout Mice","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Acetyltransferases; Knockout mouse; Arylamine N-acetyltransferase; Molecular biology; Biology; In vivo; Isozyme; Carcinogen; Spleen; Enzyme; Phenotype; Chemistry; Biochemistry; Acetylation; Gene; Genetics; Immunology","score_opus":0.01932640318806935,"score_gpt":0.2603515081823625,"score_spread":0.24102510499429317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104551057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9595887,0.00030187823,0.03809058,0.0005288946,0.00051808025,0.0003302835,0.000009832056,0.000025456597,0.0006062632],"genre_scores_gemma":[0.9971129,0.0001339887,0.00065050175,0.0010078603,0.000095519885,0.000029029952,0.00026878173,0.000020340398,0.00068110396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918896,0.00005696981,0.00022639448,0.00022318524,0.00014774501,0.00015677142],"domain_scores_gemma":[0.9996706,0.000008911544,0.00005146987,0.00007753443,0.00010455834,0.00008692821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012637288,0.0001249062,0.00021826677,0.000103196675,0.0000462679,0.0000037202956,0.000023576918,0.000096826785,0.00042998543],"category_scores_gemma":[0.0000057137513,0.00011988209,0.000056721357,0.00013149338,0.00007578921,0.000048329704,0.0000040101795,0.00011127383,0.0000047083686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002032267,0.00015361962,0.00022343043,0.00007137548,0.00008894078,0.0000734979,0.000062037194,0.000017048797,0.996598,0.0021056933,0.00006960826,0.0003335165],"study_design_scores_gemma":[0.002884238,0.00014553989,0.002398369,0.000010277602,0.0002205563,0.000082360166,0.000011780338,0.00028431555,0.9886791,0.00002729433,0.005153415,0.00010274301],"about_ca_topic_score_codex":0.0000016493091,"about_ca_topic_score_gemma":0.000002107454,"teacher_disagreement_score":0.03752414,"about_ca_system_score_codex":0.000021377782,"about_ca_system_score_gemma":0.00007388129,"threshold_uncertainty_score":0.488865},"labels":[],"label_agreement":null},{"id":"W2105794608","doi":"10.1124/mol.104.000224","title":"Identification of the P2Y12 Receptor in Nucleotide Inhibition of Exocytosis from Bovine Chromaffin Cells","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Leeds; University of Leicester; Ryerson University; AstraZeneca","keywords":"Chromaffin cell; Exocytosis; P2Y receptor; PPADS; Nucleotide; Adenine nucleotide; Biology; Receptor; Chemistry; Biochemistry; Biophysics; Agonist; Endocrinology; Adrenal medulla; Secretion; Catecholamine","score_opus":0.005725370001095353,"score_gpt":0.23983331239900665,"score_spread":0.2341079423979113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105794608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99640614,0.0010690832,0.0016352348,0.00033556466,0.00024352361,0.00020567612,0.00004232354,0.0000045612373,0.000057869744],"genre_scores_gemma":[0.99921066,0.00008090197,0.00021989243,0.00027114496,0.00008796813,0.000017704862,0.00006496177,0.000016575252,0.000030179923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990247,0.00011889729,0.00037705037,0.00023324972,0.00010603824,0.00014005705],"domain_scores_gemma":[0.999464,0.000011109882,0.00022264806,0.00021075613,0.00006362167,0.000027876893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013120311,0.00010815906,0.00015441445,0.000054256987,0.000022897426,0.0000031648628,0.00017659111,0.00011735736,0.000079480305],"category_scores_gemma":[0.00002408644,0.00009890513,0.00009667851,0.00017603248,0.00009815851,0.0000040895566,0.000102230406,0.00008757918,0.0000058545147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007940324,0.0001415115,0.00022436494,0.000014816639,0.0000411067,0.0000044142407,0.00006926035,0.0031130903,0.9945208,0.00004570977,0.0016740416,0.00007149025],"study_design_scores_gemma":[0.0011940073,0.00009753628,0.0013794403,0.000019089282,0.00004050975,0.0000015396153,0.00002277387,0.000026934784,0.99644583,0.00014439842,0.000536385,0.0000915291],"about_ca_topic_score_codex":0.00017031546,"about_ca_topic_score_gemma":0.000011216178,"teacher_disagreement_score":0.0030861555,"about_ca_system_score_codex":0.000024661926,"about_ca_system_score_gemma":0.00007166163,"threshold_uncertainty_score":0.4033234},"labels":[],"label_agreement":null},{"id":"W2106169706","doi":"10.1124/mol.106.022608","title":"Liver X Receptor (LXR)-β Regulation in LXRα-Deficient Mice: Implications for Therapeutic Targeting","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":151,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Liver X receptor; ABCA1; Nuclear receptor; Internal medicine; Endocrinology; Cholesterol; Biology; Reverse cholesterol transport; Lipogenesis; Cholesterol 7 alpha-hydroxylase; Liver X receptor alpha; Sterol regulatory element-binding protein; Chemistry; Lipoprotein; Lipid metabolism; Transcription factor; Sterol; Biochemistry; Medicine; Transporter; Gene","score_opus":0.015273834510243759,"score_gpt":0.3085217369622992,"score_spread":0.2932479024520554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106169706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97448254,0.0035190212,0.011118897,0.008320003,0.00056139386,0.0012011847,0.000014953415,0.00006488647,0.0007170966],"genre_scores_gemma":[0.99413514,0.00005260581,0.0017822832,0.0026870377,0.0004491023,0.00025847746,0.0001643733,0.000029153653,0.0004418441],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989598,0.00007955697,0.00029040832,0.00029126863,0.00008174923,0.00029722683],"domain_scores_gemma":[0.9995791,0.000052173586,0.00008343405,0.00012820546,0.00010059934,0.0000565439],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021802729,0.00012833087,0.00021549464,0.00014906705,0.000061724895,0.000009680127,0.0000726096,0.00010096425,0.00017779272],"category_scores_gemma":[0.000013867992,0.00012490811,0.00009750778,0.00020655354,0.00004625092,0.000038451923,0.000023637876,0.00013392963,0.000026837959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011971082,0.00025133617,0.0015574818,0.000039033897,0.000024785864,0.0000035965982,0.00007522643,0.0002663036,0.98396397,0.0017079773,0.007828067,0.0041625095],"study_design_scores_gemma":[0.0071546333,0.00017234117,0.20434639,0.000024435087,0.00037044912,0.00003852158,0.00003539347,0.0034584021,0.42180082,0.0011975025,0.36109772,0.00030339777],"about_ca_topic_score_codex":0.00003843884,"about_ca_topic_score_gemma":0.000005300038,"teacher_disagreement_score":0.5621632,"about_ca_system_score_codex":0.00008182509,"about_ca_system_score_gemma":0.000049927625,"threshold_uncertainty_score":0.5093605},"labels":[],"label_agreement":null},{"id":"W2106743210","doi":"10.1124/mol.115.098897","title":"A Perspective on Studying G-Protein–Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms","year":2015,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute on Drug Abuse","keywords":"G protein-coupled receptor; Förster resonance energy transfer; Biosensor; Cell biology; Biology; In vivo; Computational biology; Signal transduction; Living cell; Receptor; Biochemistry; Biotechnology; Physics; Fluorescence","score_opus":0.02434166380676032,"score_gpt":0.30519863735378294,"score_spread":0.2808569735470226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106743210","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016145932,0.977951,0.0037831531,0.00004239353,0.00038790808,0.0013390144,0.00003471021,0.000048572467,0.00026733792],"genre_scores_gemma":[0.027869418,0.96754766,0.0012563491,0.0005799487,0.0006770926,0.00086336833,0.0001683945,0.00044881654,0.0005889568],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954955,0.0010508943,0.00070674357,0.0015024423,0.00042014552,0.00082428125],"domain_scores_gemma":[0.9987282,0.00006932637,0.00022724239,0.00045960612,0.00027394173,0.00024169344],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007072185,0.00092578173,0.0016199525,0.00038297576,0.00012459746,0.000050952505,0.00058999326,0.00077620463,0.0003540125],"category_scores_gemma":[0.00007407597,0.0008044452,0.00039062108,0.00058388023,0.000120905344,0.000007906349,0.00016228433,0.000696459,0.000026624219],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000309758,0.0003875756,7.9716574e-7,0.0007398651,0.000713495,0.00041863456,0.00034377928,0.00027485617,0.9542206,0.0007750536,0.0002046926,0.041610897],"study_design_scores_gemma":[0.00166234,0.002030307,1.2704524e-7,0.0040434217,0.0005861267,0.00007524248,0.0004106955,0.000057828103,0.3241435,0.000039074308,0.6654305,0.0015208339],"about_ca_topic_score_codex":0.0000837846,"about_ca_topic_score_gemma":0.0000236471,"teacher_disagreement_score":0.6652258,"about_ca_system_score_codex":0.0004316054,"about_ca_system_score_gemma":0.0006909473,"threshold_uncertainty_score":0.99944067},"labels":[],"label_agreement":null},{"id":"W2106818541","doi":"10.1124/mol.109.059022","title":"CCR2 Receptor Ligands Inhibit Cav3.2 T-Type Calcium Channels","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"T-type calcium channel; Voltage-dependent calcium channel; Chemistry; Calcium; Receptor; Calcium channel; CCR2; Ion channel; Biophysics; Chemotaxis; Cell biology; Biochemistry; Chemokine; Chemokine receptor; Biology","score_opus":0.020272765645026496,"score_gpt":0.33308355131007533,"score_spread":0.31281078566504883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106818541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98711675,0.0009533566,0.0012821244,0.005756274,0.001369367,0.0005773183,0.000005613784,0.00015404673,0.0027851204],"genre_scores_gemma":[0.9828277,0.000073462565,0.00090929575,0.013885258,0.00030477924,0.000025244999,0.000064047286,0.000028544195,0.001881656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987452,0.000060340342,0.00020931457,0.0003546009,0.0001882422,0.00044231582],"domain_scores_gemma":[0.9993609,0.000017082632,0.0000592187,0.0001949039,0.00010336877,0.0002645088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014615114,0.00021844672,0.00035912794,0.00013003117,0.00007446455,0.000010468665,0.00009127728,0.00016807043,0.00078617537],"category_scores_gemma":[0.000025682417,0.00019705803,0.000114635186,0.0002564735,0.000035650493,0.000035743808,0.000032724558,0.00022400815,0.00041108925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024324644,0.0004583119,0.000083460676,0.0000136102435,0.00016554011,0.0011825301,0.000104953906,0.0000126119585,0.981698,0.00032448318,0.012492661,0.0032206154],"study_design_scores_gemma":[0.003671891,0.0014862871,0.00024063615,0.000021492127,0.000261667,0.00011225509,0.000013623676,0.0002088491,0.9726639,0.00036721674,0.020776402,0.00017579229],"about_ca_topic_score_codex":0.000010039986,"about_ca_topic_score_gemma":1.8372735e-7,"teacher_disagreement_score":0.009034088,"about_ca_system_score_codex":0.00009520062,"about_ca_system_score_gemma":0.00008848074,"threshold_uncertainty_score":0.8608069},"labels":[],"label_agreement":null},{"id":"W2106841375","doi":"10.1124/mol.105.018671","title":"Implication of the Phosphatidylinositol-3 Kinase/Protein Kinase B Signaling Pathway in the Neuroprotective Effect of Estradiol in the Striatum of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mice","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Université Laval","keywords":"MPTP; Endocrinology; Internal medicine; Protein kinase B; Estrogen receptor; Neuroprotection; Agonist; Chemistry; Kinase; Pharmacology; Receptor; Signal transduction; Dopamine; Biology; Biochemistry; Medicine; Dopaminergic","score_opus":0.0033960597940592492,"score_gpt":0.23562767044985378,"score_spread":0.23223161065579453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106841375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99489707,0.002594174,0.00013755442,0.00028081928,0.00010644221,0.0018101805,0.000020322404,0.000004162718,0.00014929431],"genre_scores_gemma":[0.999519,0.000026094041,0.00004764137,0.000111795984,0.000062322724,0.00017748102,0.000028216122,0.00002244612,0.000005028403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99676543,0.0018811609,0.00050055486,0.00033151286,0.00023591942,0.000285437],"domain_scores_gemma":[0.9989355,0.0001799326,0.00037774252,0.00041587205,0.00006814632,0.000022777602],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009865161,0.00023611456,0.00032140338,0.00008531298,0.000053471013,0.000006207851,0.0006656287,0.00023462092,0.000003497041],"category_scores_gemma":[0.000096165015,0.00013815875,0.00022623457,0.0005500403,0.00024218054,0.000005398239,0.000083933504,0.000435256,5.693681e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042543275,0.00028499888,0.0006772259,0.00009041631,0.000057396617,0.000034768003,0.0001080095,0.0023284303,0.99526155,0.00017232337,0.00004013508,0.00051930675],"study_design_scores_gemma":[0.0018114985,0.0011557909,0.0024003356,0.000037567894,0.000085339,0.000021769572,0.000040135088,0.0002355,0.99389815,0.00010319643,0.00008952867,0.00012117623],"about_ca_topic_score_codex":0.00031360867,"about_ca_topic_score_gemma":0.00001040844,"teacher_disagreement_score":0.004621924,"about_ca_system_score_codex":0.000021726206,"about_ca_system_score_gemma":0.000081870094,"threshold_uncertainty_score":0.563395},"labels":[],"label_agreement":null},{"id":"W2107376987","doi":"10.1124/mol.107.041624","title":"A Three-Dimensional Quantitative Structure-Activity Analysis of a New Class of Bisphenol Topoisomerase IIα Inhibitors","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute","keywords":"Topoisomerase; Class (philosophy); Bisphenol A; Chemistry; Computational biology; Biochemistry; Biology; Computer science; Enzyme; Artificial intelligence; Organic chemistry","score_opus":0.016111913666307726,"score_gpt":0.319153668742169,"score_spread":0.3030417550758613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107376987","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9399427,0.0008645383,0.058417443,0.000104191735,0.00031376135,0.00021091569,0.000080794176,0.000006088927,0.000059524984],"genre_scores_gemma":[0.9968587,0.000019364204,0.0024391934,0.000498727,0.00006349731,0.0000046180016,0.00006235734,0.000021478512,0.000032034113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878645,0.00005635651,0.00032700668,0.00035610877,0.00019560108,0.00027849808],"domain_scores_gemma":[0.99918175,0.000028032764,0.00026638727,0.00024041494,0.00015845965,0.00012495824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020001529,0.00018791718,0.00038852202,0.00024825416,0.00003186422,0.0000034199006,0.00016550081,0.00017657092,0.0001564356],"category_scores_gemma":[0.00001557889,0.00018911253,0.00027507308,0.00054164487,0.00012742775,0.0000035292007,0.0001077348,0.00011607848,7.2249907e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008509678,0.00013487799,0.00024658797,0.000013799134,0.0022379009,0.000015813363,0.00006436182,0.001626948,0.9900505,0.0006398912,0.00024876592,0.0038695927],"study_design_scores_gemma":[0.0011052592,0.0005918933,0.0011117741,0.0000035939024,0.00090035703,0.000004065836,0.000019590037,0.0010260936,0.9925393,0.0002987568,0.0022240013,0.00017533606],"about_ca_topic_score_codex":0.00035754664,"about_ca_topic_score_gemma":0.0007861266,"teacher_disagreement_score":0.05691599,"about_ca_system_score_codex":0.000026176658,"about_ca_system_score_gemma":0.00019408755,"threshold_uncertainty_score":0.7711785},"labels":[],"label_agreement":null},{"id":"W2107818111","doi":"10.1124/mol.107.039982","title":"Role of Extracellular Domain Dimerization in Agonist-Induced Activation of Natriuretic Peptide Receptor A","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Atrial natriuretic peptide; Agonist; Receptor; Ligand (biochemistry); Dimer; Peptide; Biophysics; Stereochemistry; Biochemistry; Biology; Endocrinology","score_opus":0.009286835791831819,"score_gpt":0.2864561018274394,"score_spread":0.2771692660356076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107818111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931609,0.00018621635,0.0037949933,0.0009168297,0.000066185035,0.00096073473,0.0000010077327,0.000017584143,0.00089555647],"genre_scores_gemma":[0.9959486,0.000016196065,0.0036826304,0.00012761103,0.000030871346,0.000036525522,0.00004359196,0.000016120952,0.00009781304],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990304,0.00008330889,0.00034892885,0.00017024053,0.0001690065,0.00019813249],"domain_scores_gemma":[0.9995943,0.000038808637,0.00012860546,0.00011665277,0.000062791245,0.000058888385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003363619,0.000105788175,0.00025003322,0.00027215888,0.000014026134,0.0000014037269,0.000046969435,0.00009269025,0.00021426062],"category_scores_gemma":[0.000024925837,0.00010594222,0.0000665362,0.00031827865,0.000041181676,0.000033199158,0.000024161685,0.00010515966,0.000008230207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003792338,0.00044174507,0.0015801891,0.000069655434,0.000095169555,0.000050240866,0.0003115715,0.000021308515,0.9921538,0.0007348606,0.00014510592,0.004017076],"study_design_scores_gemma":[0.002559226,0.00036352975,0.0034959973,0.00003513052,0.00009841342,0.0000034730715,0.00016908215,0.000103626706,0.9851023,0.00010104453,0.0078965165,0.000071643364],"about_ca_topic_score_codex":0.000048273123,"about_ca_topic_score_gemma":0.0000049487976,"teacher_disagreement_score":0.0077514104,"about_ca_system_score_codex":0.000083807914,"about_ca_system_score_gemma":0.000052051186,"threshold_uncertainty_score":0.43201986},"labels":[],"label_agreement":null},{"id":"W2108194180","doi":"10.1124/mol.112.079004","title":"Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Barbara Ann Karmanos Cancer Institute; Mesothelioma Applied Research Foundation","keywords":"Transporter; Intracellular; HeLa; Transfection; Cofactor; Biochemistry; Chemistry; Pyrimidine; Enzyme; In vitro; Molecular biology; Biology; Gene","score_opus":0.01742528617335181,"score_gpt":0.2989013339575386,"score_spread":0.2814760477841868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108194180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947782,0.0008874759,0.0003893536,0.0014996238,0.00024854648,0.0018657258,0.000052372074,0.000015063625,0.00026364147],"genre_scores_gemma":[0.99860144,0.00006203892,0.000031734504,0.0004020492,0.00009787414,0.00024823582,0.000013419688,0.000033730103,0.00050950417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983039,0.00017153997,0.0003169394,0.00024145613,0.00048071888,0.00048543772],"domain_scores_gemma":[0.9990639,0.0001306309,0.00020516856,0.0002938511,0.00022703584,0.000079390564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004950874,0.00022206183,0.0003724218,0.00006871225,0.00019005677,0.000009262137,0.00026737442,0.000099474666,0.00020308331],"category_scores_gemma":[0.000020392801,0.00010004103,0.00018326647,0.00044765946,0.00073153764,0.00012492143,0.000052301355,0.00048650018,0.0000020669486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013780181,0.00043953324,0.006647467,0.00009792169,0.0010270358,0.000010110087,0.0010169358,0.000021352624,0.98864496,0.00006295178,0.00048289436,0.00017079862],"study_design_scores_gemma":[0.0023776805,0.0005634949,0.033110086,0.00003637566,0.00049968984,0.00013874753,0.00020498325,0.00034763973,0.96173537,0.000013766077,0.0008574781,0.00011466784],"about_ca_topic_score_codex":0.000100347206,"about_ca_topic_score_gemma":0.000010764591,"teacher_disagreement_score":0.026909588,"about_ca_system_score_codex":0.000037190523,"about_ca_system_score_gemma":0.00026034,"threshold_uncertainty_score":0.40795544},"labels":[],"label_agreement":null},{"id":"W2108527751","doi":"10.1124/mol.109.059410","title":"Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor α in Cultured Glial Cells: Involvement of Nuclear Factor-κB and c-Jun N-Terminal Kinase Signaling Pathways","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Tumor necrosis factor alpha; Astrocyte; Biology; Microglia; P-glycoprotein; ATP-binding cassette transporter; Molecular biology; Proinflammatory cytokine; Cytokine; Cell biology; Multiple drug resistance; Pharmacology; Immunology; Inflammation; Transporter; Endocrinology; Biochemistry; Drug resistance; Microbiology; Central nervous system; Gene","score_opus":0.009071367121078784,"score_gpt":0.24233062915407672,"score_spread":0.23325926203299793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108527751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99814034,0.00015780178,0.00023994391,0.00014063474,0.00020071634,0.0009265359,0.00012364383,0.000023795528,0.000046588306],"genre_scores_gemma":[0.9955131,0.000012312762,0.004068208,0.00014362817,0.000033517477,0.00003688832,0.000037298894,0.00003300975,0.000122067904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998556,0.00007594829,0.00048626558,0.00034324342,0.0002702951,0.00026824747],"domain_scores_gemma":[0.9993303,0.000017405426,0.00024776362,0.00016500706,0.00011115169,0.00012838302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014578765,0.00020969645,0.00043923577,0.00012289154,0.000043551856,0.0000062971612,0.00011182587,0.00014839298,0.00020367892],"category_scores_gemma":[0.00001315925,0.00019164948,0.00009571066,0.00014945859,0.00016789335,0.000057948146,0.00002850053,0.000308292,0.0000012515919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008456989,0.00036597054,0.0003653603,0.00047161433,0.0000459724,0.00018192474,0.0010896355,0.000005480224,0.99624246,0.00010450653,0.000088956804,0.000192433],"study_design_scores_gemma":[0.003425552,0.00017530964,0.0015811227,0.00012749356,0.000081377926,0.000003152171,0.00011590616,0.0002345728,0.9931425,0.000074927506,0.00087121024,0.0001668704],"about_ca_topic_score_codex":0.00005525973,"about_ca_topic_score_gemma":0.0000584406,"teacher_disagreement_score":0.0038282638,"about_ca_system_score_codex":0.00003922312,"about_ca_system_score_gemma":0.00006709562,"threshold_uncertainty_score":0.7815239},"labels":[],"label_agreement":null},{"id":"W2108767516","doi":"10.1124/mol.113.089847","title":"Allosteric Noncompetitive Small Molecule Selective Inhibitors of CD45 Tyrosine Phosphatase Suppress T-Cell Receptor Signals and Inflammation In Vivo","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; National Research Council Canada; Biotechnology Research Institute; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Allosteric regulation; In vivo; Protein tyrosine phosphatase; Chemistry; Receptor; Inflammation; Biochemistry; Phosphatase; Pharmacology; Enzyme; Biology; Immunology; Biotechnology","score_opus":0.004730804581274202,"score_gpt":0.2296745291608017,"score_spread":0.2249437245795275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108767516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899296,0.0059573255,0.0023199208,0.00018943573,0.00019390795,0.0007928856,0.0001574838,0.000018591381,0.00044084646],"genre_scores_gemma":[0.99730384,0.00022566771,0.0012565821,0.0005230463,0.00013414162,0.00016158874,0.00029473024,0.000048875416,0.000051536772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979291,0.0004253776,0.00046289267,0.00059554673,0.0001492015,0.00043788247],"domain_scores_gemma":[0.9990947,0.000058475336,0.00027013867,0.00025613885,0.00017693403,0.00014357718],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035979287,0.00031347477,0.00037112975,0.00014960814,0.000046536272,0.000017070299,0.0002479677,0.00021601186,0.000087447756],"category_scores_gemma":[0.00012910875,0.00034848586,0.00008241252,0.00024530484,0.00021140346,0.00001391249,0.00029265662,0.00017267681,0.000008060704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042406007,0.00015689462,0.00039950846,0.00009333145,0.000058277186,0.000018322637,0.00007218545,0.0003292567,0.9962902,0.0002064743,0.0014502114,0.0005012615],"study_design_scores_gemma":[0.002673959,0.0007843,0.00013215344,0.00003196073,0.000057340483,0.000010431482,0.000020602976,0.00031690826,0.9913766,0.00005221464,0.0042134477,0.0003301222],"about_ca_topic_score_codex":0.00008176881,"about_ca_topic_score_gemma":0.000026267553,"teacher_disagreement_score":0.0073742284,"about_ca_system_score_codex":0.000037772086,"about_ca_system_score_gemma":0.00008671025,"threshold_uncertainty_score":0.9998967},"labels":[],"label_agreement":null},{"id":"W2108911843","doi":"10.1124/mol.112.079277","title":"Extracellular Quaternary Ammonium Blockade of Transient Receptor Potential Vanilloid Subtype 1 Channels Expressed in Xenopus laevis Oocytes","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Xenopus; Transient receptor potential channel; Extracellular; Cell biology; Chemistry; Blockade; Receptor; Salientia; Biology; Neuroscience; Biochemistry; Gene","score_opus":0.019783403232688564,"score_gpt":0.27308425342785386,"score_spread":0.2533008501951653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108911843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99007267,0.0020443515,0.0009565811,0.0006372978,0.0055552623,0.00052322686,0.000030563715,0.00006423995,0.00011578195],"genre_scores_gemma":[0.9981425,0.00036119542,0.00013712939,0.00031099463,0.0004255826,0.00006919222,0.000010845585,0.00005787121,0.00048472133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971873,0.0005630935,0.00052606803,0.00050569937,0.00035979337,0.0008580378],"domain_scores_gemma":[0.99925995,0.00008143376,0.00020192045,0.00016931121,0.000047518068,0.00023983828],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00033189147,0.0003061009,0.00042072238,0.00027811018,0.00008279613,0.00001536133,0.0004307799,0.00022070999,0.0009903327],"category_scores_gemma":[0.000044268603,0.00029139282,0.00018668154,0.00038104737,0.00020559209,0.00017445828,0.00011418382,0.00034863004,0.00010351299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034269507,0.00065920764,0.00006127302,0.00005677025,0.000021530082,0.00013171103,0.0009104114,0.0021024884,0.9947557,0.0000852468,0.0006135496,0.00025944514],"study_design_scores_gemma":[0.0013935476,0.00017396557,0.000015345317,0.000017644423,0.00004605485,0.000032280484,0.000068977264,0.0016112064,0.9858248,0.000025540632,0.010490735,0.00029985438],"about_ca_topic_score_codex":0.000052401952,"about_ca_topic_score_gemma":5.782806e-7,"teacher_disagreement_score":0.009877185,"about_ca_system_score_codex":0.000061166385,"about_ca_system_score_gemma":0.000047044643,"threshold_uncertainty_score":0.9999538},"labels":[],"label_agreement":null},{"id":"W2109498048","doi":"10.1124/mol.109.055277","title":"Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Head and neck; Apoptosis; Cancer; Head and neck cancer; Cancer research; Medicine; Chemistry; Internal medicine; Biochemistry; Surgery","score_opus":0.020679051642177454,"score_gpt":0.36003267196002087,"score_spread":0.33935362031784344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109498048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956796,0.0011511027,0.0014401878,0.0007015894,0.00028396194,0.0006304997,0.00005434756,0.000015183047,0.000043481436],"genre_scores_gemma":[0.995881,0.0003636148,0.0015948907,0.001531534,0.00026887975,0.000083778505,0.00008074941,0.000036999092,0.00015850595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832755,0.0001604488,0.00029766682,0.00055091333,0.00018398926,0.00047942193],"domain_scores_gemma":[0.99923027,0.00001614727,0.0001179946,0.00025089987,0.000203182,0.00018153967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018434998,0.0002059185,0.00027018957,0.00010500844,0.00010210708,0.000025777152,0.00018922886,0.00019627059,0.00004098447],"category_scores_gemma":[0.00007725146,0.00022297858,0.00012019829,0.00011936116,0.00015947415,0.000012783783,0.00009563013,0.00014428537,0.0000021699657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005493262,0.00022046818,0.00014049406,0.00004457511,0.00009815269,0.000018826675,0.000054519067,0.00032160667,0.99090534,0.000024560917,0.0023436814,0.0052784295],"study_design_scores_gemma":[0.001872062,0.0014321293,0.00055146473,0.000016394832,0.000084612315,0.000020534155,0.00000983135,0.00092086784,0.98422706,0.00003027999,0.010615449,0.00021932824],"about_ca_topic_score_codex":0.00016851969,"about_ca_topic_score_gemma":0.000015045772,"teacher_disagreement_score":0.008271769,"about_ca_system_score_codex":0.00004350812,"about_ca_system_score_gemma":0.00017424942,"threshold_uncertainty_score":0.90928024},"labels":[],"label_agreement":null},{"id":"W2109918049","doi":"10.1124/mol.107.038794","title":"Separating Transrepression and Transactivation: A Distressing Divorce for the Glucocorticoid Receptor?","year":2007,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":328,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Transrepression; Transactivation; Glucocorticoid receptor; Transcription factor; Biology; Glucocorticoid; Context (archaeology); Psychological repression; Proinflammatory cytokine; Cancer research; Inflammation; Cell biology; Gene; Gene expression; Genetics; Immunology","score_opus":0.032529245694031275,"score_gpt":0.39087946872526125,"score_spread":0.35835022303123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109918049","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011394211,0.96641755,0.029795773,0.00006691423,0.00054091396,0.0018771657,0.00003082394,0.000019015659,0.00011243295],"genre_scores_gemma":[0.0021771952,0.995865,0.0003773626,0.00022614961,0.00032813603,0.00038622995,0.000332995,0.00008987259,0.00021707853],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981997,0.0002509362,0.00042895688,0.0006092354,0.00011742353,0.00039375277],"domain_scores_gemma":[0.99912614,0.00022101747,0.00024066563,0.00027046667,0.000047190297,0.00009453816],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031783246,0.00041109248,0.00062330376,0.000062184714,0.00022965862,0.000035789304,0.00025014658,0.0006390561,0.000017342783],"category_scores_gemma":[0.000026300559,0.00028573122,0.00043314285,0.00013841678,0.00015112475,0.0000040094847,0.00006132358,0.00040913225,0.0000049175233],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011548128,0.00004707552,8.792208e-7,0.002614208,0.0006836733,0.000014210792,0.000036711197,0.00006210952,0.18855542,0.000018141991,0.0006437743,0.8072083],"study_design_scores_gemma":[0.00076716515,0.00021583104,4.3135327e-7,0.00062691374,0.0013514289,0.00008929096,0.000012152975,0.00016218265,0.06343256,0.0000030469716,0.9329883,0.00035071315],"about_ca_topic_score_codex":0.0000022222496,"about_ca_topic_score_gemma":3.7217373e-7,"teacher_disagreement_score":0.9323445,"about_ca_system_score_codex":0.000024897332,"about_ca_system_score_gemma":0.00013227868,"threshold_uncertainty_score":0.99995947},"labels":[],"label_agreement":null},{"id":"W2110695376","doi":"10.1124/mol.105.018622","title":"Chemical Inducers of Rodent Glutathione S-Transferases Down-Regulate Human GSTA1 Transcription through a Mechanism Involving Variant Hepatic Nuclear Factor 1-C","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Transcription factor; Rodent; Glutathione; Inducer; Glutathione transferase; Mechanism (biology); Chemistry; Biology; Transcription (linguistics); Cell biology; Biochemistry; Molecular biology; Enzyme; Gene","score_opus":0.01051193604502934,"score_gpt":0.25083372133548104,"score_spread":0.2403217852904517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110695376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858891,0.00085239805,0.011665331,0.00035972433,0.00038186376,0.00050241116,0.00011528103,0.00005171955,0.00018219104],"genre_scores_gemma":[0.9975603,0.00017374344,0.0008218684,0.00077843113,0.00020646129,0.000044896045,0.0002862558,0.00008384295,0.000044176766],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99772847,0.00022628218,0.00060728093,0.000622441,0.00027988802,0.00053566176],"domain_scores_gemma":[0.99933237,0.000014380042,0.0001187579,0.0003104123,0.00010375307,0.00012033766],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013450926,0.00039396904,0.0004310529,0.0000958275,0.00014245811,0.000023974071,0.00031389116,0.00036648556,0.00033350807],"category_scores_gemma":[0.0000068697004,0.00041307817,0.00033568987,0.00016649002,0.00019406773,0.00001749609,0.00005584303,0.00025129592,0.000010263076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021991631,0.0003956164,0.000026308848,0.000080927704,0.0002074801,0.00011811868,0.00026130202,0.00021915711,0.9899191,0.008242653,0.00019127235,0.000118107164],"study_design_scores_gemma":[0.002449326,0.000439902,0.00020098753,0.00002532159,0.00024080851,0.000086409695,0.000041145504,0.00019322862,0.9934933,0.0014646942,0.00093956594,0.0004253139],"about_ca_topic_score_codex":0.00055956794,"about_ca_topic_score_gemma":0.000039592946,"teacher_disagreement_score":0.011671244,"about_ca_system_score_codex":0.000048244317,"about_ca_system_score_gemma":0.00007640632,"threshold_uncertainty_score":0.9998321},"labels":[],"label_agreement":null},{"id":"W2110841276","doi":"10.1124/mol.110.068411","title":"Copper Transporter 2 Regulates Endocytosis and Controls Tumor Growth and Sensitivity to Cisplatin In Vivo","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Health Canada; National Institutes of Health; U.S. Department of Defense","keywords":"Gene knockdown; Pinocytosis; Endocytosis; Wortmannin; Biology; Cell biology; CDC42; In vivo; Chemistry; Molecular biology; Signal transduction; Apoptosis; Biochemistry; Receptor; PI3K/AKT/mTOR pathway","score_opus":0.004377595024460046,"score_gpt":0.24734298849199904,"score_spread":0.24296539346753898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110841276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99513775,0.00013525678,0.0003419989,0.0029738261,0.00020696841,0.00063039054,0.000020839105,0.000034424807,0.00051856734],"genre_scores_gemma":[0.99436224,0.000025808386,0.0010820985,0.0043172333,0.000054800996,0.000046163732,0.0000062087024,0.00002536578,0.0000800846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893284,0.000054133383,0.00022190395,0.00035575835,0.000118333024,0.00031705655],"domain_scores_gemma":[0.9995339,0.00005250079,0.000034510434,0.000103144346,0.000037665402,0.00023828876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022041245,0.00018052646,0.0004178786,0.00015041289,0.000039708575,0.000008629942,0.000025823874,0.00009945312,0.0001547494],"category_scores_gemma":[0.000013207317,0.00016073258,0.000051234194,0.0001155379,0.00011542188,0.000037661495,0.000013674021,0.00029070216,0.0000032613923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051782874,0.000086529944,0.007381009,0.00007137113,0.000045853074,0.004144853,0.00019641832,0.0000022002846,0.98678356,0.00035255315,0.00011338476,0.00030443777],"study_design_scores_gemma":[0.0042954516,0.00014721432,0.031109395,0.000025290528,0.00019055593,0.00044869795,0.00002469603,0.00015359299,0.96198624,0.00010896316,0.0013337699,0.00017611847],"about_ca_topic_score_codex":0.00003867834,"about_ca_topic_score_gemma":0.00015356191,"teacher_disagreement_score":0.024797305,"about_ca_system_score_codex":0.000009676326,"about_ca_system_score_gemma":0.00003262593,"threshold_uncertainty_score":0.65544844},"labels":[],"label_agreement":null},{"id":"W2111014532","doi":"10.1124/mol.110.065896","title":"Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Mesothelioma Applied Research Foundation; National Eye Institute; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Barbara Ann Karmanos Cancer Institute","keywords":"Chinese hamster ovary cell; Antifolate; Biochemistry; Chemistry; Pyrimidine; Purine; Purine metabolism; Stereochemistry; Biology; Methotrexate; Antimetabolite; Enzyme","score_opus":0.011150079962468256,"score_gpt":0.3115547720023202,"score_spread":0.30040469203985193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111014532","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99524003,0.0001680421,0.0002644359,0.0012691433,0.00008212327,0.0028972612,0.000031776475,0.00001248049,0.00003469919],"genre_scores_gemma":[0.9987287,0.00012386656,0.0004180529,0.0003320944,0.000068275716,0.00026784625,0.000016770557,0.00003593741,0.000008460372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824774,0.00015173826,0.00062763714,0.00026341467,0.00026930653,0.00044016575],"domain_scores_gemma":[0.9988426,0.00026185144,0.0002571326,0.0002372887,0.0003428078,0.000058337104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012610133,0.00019886883,0.00056657137,0.0002754019,0.00005378042,0.000003242736,0.00032270834,0.00016182651,0.000077857796],"category_scores_gemma":[0.00010263546,0.00012582952,0.00022436785,0.00057747436,0.00036181248,0.000047983653,0.000027699038,0.0004805199,7.3986666e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021755646,0.00060264976,0.0039676423,0.00035794644,0.00037178057,0.000086136555,0.0010067824,0.0000842327,0.99067485,0.00001724346,0.00006943856,0.0005857319],"study_design_scores_gemma":[0.003703711,0.00065703207,0.006193569,0.000046286783,0.00021238432,0.000044388384,0.00009595467,0.005754081,0.982974,0.000049308517,0.00016307338,0.00010619085],"about_ca_topic_score_codex":0.00014935803,"about_ca_topic_score_gemma":0.000023076956,"teacher_disagreement_score":0.0077008307,"about_ca_system_score_codex":0.000026985044,"about_ca_system_score_gemma":0.00025166283,"threshold_uncertainty_score":0.5131179},"labels":[],"label_agreement":null},{"id":"W2112482916","doi":"10.1124/mol.113.089649","title":"Identification of Novel Functionally Selective κ-Opioid Receptor Scaffolds","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; National Institute of General Medical Sciences; National Institute on Drug Abuse; Wellcome Trust","keywords":"Arrestin; Functional selectivity; Pharmacology; Dynorphin; G protein-coupled receptor; Dysphoria; Neuroscience; Opioid; Chemistry; Receptor; Medicine; Biology; Opioid peptide; Biochemistry","score_opus":0.00716458064414528,"score_gpt":0.2511987866810394,"score_spread":0.24403420603689413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112482916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93203384,0.00031954327,0.06606002,0.00016900449,0.0006556857,0.0003871529,0.000015960246,0.000015924246,0.00034287153],"genre_scores_gemma":[0.9966106,0.00004817857,0.001707689,0.0005746393,0.00020134012,0.00015298219,0.000109923065,0.00002940146,0.0005652478],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884194,0.000078404046,0.00033104836,0.00036227316,0.00014963362,0.0002367282],"domain_scores_gemma":[0.99921846,0.000011431737,0.00017986454,0.00017538444,0.00033547592,0.000079367586],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018174271,0.00015379976,0.0001614945,0.00007691337,0.000060762974,0.000014964408,0.00019534283,0.00017383171,0.001182897],"category_scores_gemma":[0.000026571577,0.00016022743,0.00011928966,0.00014119357,0.000069582755,0.000007810563,0.00007658522,0.000065431894,0.00006629568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043099983,0.00015241014,0.000053063588,0.000013954782,0.00014032036,6.1244504e-7,0.00003058885,0.00036898736,0.99174327,0.00027852083,0.0063638575,0.00081130833],"study_design_scores_gemma":[0.00071568997,0.00021844618,0.00021748795,0.000003172473,0.000037051206,0.000007578427,0.00003493727,0.0005934703,0.9930725,0.00013516043,0.0048041767,0.00016032449],"about_ca_topic_score_codex":0.000018891687,"about_ca_topic_score_gemma":8.5649583e-7,"teacher_disagreement_score":0.06457676,"about_ca_system_score_codex":0.000021380176,"about_ca_system_score_gemma":0.00008316645,"threshold_uncertainty_score":0.99973017},"labels":[],"label_agreement":null},{"id":"W2112910994","doi":"10.1124/mol.106.028878","title":"[d-Trp8]-γ-Melanocyte-Stimulating Hormone Exhibits Anti-Inflammatory Efficacy in Mice Bearing a Nonfunctional MC1R (Recessive Yellow e/e Mouse)","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Sherbrooke","keywords":"Melanocortins; Melanocortin; Melanocortin 1 receptor; Agonist; Molecular biology; Internal medicine; Endocrinology; Receptor; Antagonist; Melanocortin receptor; Melanocyte-stimulating hormone; Chemistry; Stereochemistry; Biology; Biochemistry; Medicine; Gene","score_opus":0.007223667164242507,"score_gpt":0.26147185544803203,"score_spread":0.25424818828378953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112910994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933279,0.0009027737,0.003256608,0.00012436313,0.00036820394,0.00040010182,0.000011758839,0.000036746835,0.001571527],"genre_scores_gemma":[0.9970753,0.00006132061,0.0007885279,0.00051020924,0.0004511698,0.00006289517,0.0004125802,0.000051471394,0.00058649405],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808025,0.00020962949,0.0004441183,0.0005822581,0.0002147282,0.00046901347],"domain_scores_gemma":[0.9994403,0.00004003311,0.00016881149,0.00017596388,0.00008566637,0.00008923267],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024480032,0.00027598508,0.00025407923,0.0001605059,0.00012143216,0.000027451604,0.00020911654,0.0002519323,0.00007683668],"category_scores_gemma":[0.000034697016,0.0003139431,0.00012077233,0.00017700803,0.00009052742,0.000011646338,0.00014025191,0.00023214573,0.000045366978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016495209,0.00021154323,0.0025609185,0.000018393832,0.000069644244,0.00014702335,0.000044077282,0.020459156,0.9735507,0.00005165759,0.0023927432,0.0003291855],"study_design_scores_gemma":[0.0037917697,0.00019527109,0.009727902,0.000011206143,0.000050393013,0.000038659004,0.000031538068,0.002236696,0.98079914,0.000025799214,0.0027329857,0.00035864234],"about_ca_topic_score_codex":0.00006840943,"about_ca_topic_score_gemma":0.00002768155,"teacher_disagreement_score":0.01822246,"about_ca_system_score_codex":0.00006660748,"about_ca_system_score_gemma":0.000089501365,"threshold_uncertainty_score":0.9999313},"labels":[],"label_agreement":null},{"id":"W2113441344","doi":"10.1124/mol.109.057489","title":"15-oxo-Eicosatetraenoic Acid, a Metabolite of Macrophage 15-Hydroxyprostaglandin Dehydrogenase That Inhibits Endothelial Cell Proliferation","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Cancer Institute; National Institutes of Health; Queen's University","keywords":"Metabolite; Macrophage; Chemistry; Cell growth; Cell; Biochemistry; Dehydrogenase; Cell biology; Biology; Enzyme; In vitro","score_opus":0.008703391068663854,"score_gpt":0.2557149348079493,"score_spread":0.24701154373928547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113441344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889059,0.0067761964,0.0013387967,0.00055840873,0.0005746769,0.00087568,0.00017950617,0.000049273865,0.0007415584],"genre_scores_gemma":[0.9894176,0.0005728978,0.00075152755,0.007987011,0.00034829762,0.00008170249,0.00036642974,0.00006226866,0.00041223236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99713784,0.00043841646,0.00058025046,0.00080656656,0.00030159115,0.00073532946],"domain_scores_gemma":[0.9987553,0.00001819501,0.00031117332,0.00041572846,0.0002007211,0.00029891537],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003528214,0.0004721785,0.0005803513,0.00023630288,0.00013969511,0.000027731094,0.0004075272,0.00042207347,0.0002891662],"category_scores_gemma":[0.000031516098,0.00045658957,0.0003069964,0.0002647842,0.00017815507,0.000017359154,0.0001625181,0.00033808692,0.00004340521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006467582,0.00061057,0.0004754906,0.00004393569,0.00015308229,0.00022698799,0.00007582078,0.0001130081,0.9930353,0.000071799914,0.003174828,0.001372414],"study_design_scores_gemma":[0.004688836,0.0010419235,0.0002452588,0.0000059303197,0.0002740767,0.00013536033,0.000016425478,0.00033309474,0.9760782,0.00012873662,0.016620468,0.0004316905],"about_ca_topic_score_codex":0.000011159076,"about_ca_topic_score_gemma":0.0000059487566,"teacher_disagreement_score":0.016957106,"about_ca_system_score_codex":0.000027375287,"about_ca_system_score_gemma":0.00018357832,"threshold_uncertainty_score":0.9997886},"labels":[],"label_agreement":null},{"id":"W2113938475","doi":"10.1124/mol.111.072314","title":"Valproic Acid Increases Formation of Reactive Oxygen Species and Induces Apoptosis in Postimplantation Embryos: A Role for Oxidative Stress in Valproic Acid-Induced Neural Tube Defects","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacological Effects and Toxicity Studies","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; Reactive oxygen species; Catalase; Apoptosis; In vivo; Neural tube; Antioxidant; Valproic Acid; Nitrotyrosine; Biology; Embryogenesis; Developmental toxicity; Chemistry; Embryo; Pharmacology; Biochemistry; Cell biology; Fetus; Pregnancy; Genetics; Epilepsy","score_opus":0.038873953361701914,"score_gpt":0.31183592278945277,"score_spread":0.27296196942775086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113938475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967961,0.00052258384,0.00013640229,0.00019635865,0.00009300882,0.0018873194,0.000053168184,0.000029978153,0.00028508407],"genre_scores_gemma":[0.9984499,0.0000982467,0.00030651593,0.00058981805,0.000038838058,0.00042853976,0.00006600097,0.000018370029,0.000003724971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843186,0.00031132967,0.0003968584,0.00034496954,0.0001525658,0.00036240407],"domain_scores_gemma":[0.9992327,0.00023574384,0.00021148344,0.000083593244,0.00013297315,0.00010348714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026802087,0.0002456972,0.00056228513,0.000375102,0.000062660736,0.0000076035467,0.00009813908,0.00014366275,0.00002488337],"category_scores_gemma":[0.00025188894,0.0002123373,0.00008413304,0.00030430427,0.00010817778,0.00023732093,0.0001011082,0.00025823552,0.0000013532408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019627155,0.00068788556,0.0037826013,0.00024614358,0.00014991398,0.0000637331,0.0020835085,0.000010162955,0.98936146,0.000048608796,0.000027465538,0.0015758201],"study_design_scores_gemma":[0.0044628195,0.0016168479,0.083148286,0.00006780993,0.0002824528,0.000027622456,0.0008441017,0.000784075,0.90836394,0.00022489228,0.000005242137,0.00017194207],"about_ca_topic_score_codex":0.00022912848,"about_ca_topic_score_gemma":0.000060942326,"teacher_disagreement_score":0.08099753,"about_ca_system_score_codex":0.000108606386,"about_ca_system_score_gemma":0.00004941189,"threshold_uncertainty_score":0.8658864},"labels":[],"label_agreement":null},{"id":"W2115253521","doi":"10.1124/mol.110.065862","title":"A Chemical Corrector Modifies the Channel Function of F508del-CFTR","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Vertex Pharmaceuticals","keywords":"Endoplasmic reticulum; Cystic fibrosis transmembrane conductance regulator; Mutant; Chemistry; Cell biology; Cystic fibrosis; Chloride channel; Mutation; ER retention; Transmembrane protein; Biophysics; Biochemistry; Biology; Receptor; Gene; Genetics","score_opus":0.011664082756121852,"score_gpt":0.3194318608475971,"score_spread":0.30776777809147526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115253521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915436,0.0003222094,0.0033148348,0.0025663476,0.0007846993,0.00045437165,0.000005795961,0.000040015806,0.00096811005],"genre_scores_gemma":[0.99806064,0.000012574181,0.00047234035,0.00088179065,0.0002147865,0.000090285685,0.000013685556,0.000018079718,0.00023579628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903363,0.0000636571,0.00017925564,0.00019968802,0.00025467383,0.0002690666],"domain_scores_gemma":[0.99933773,0.00012600058,0.00006023362,0.00021207613,0.00015252158,0.000111409754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018171658,0.00010915114,0.00021168792,0.00007314972,0.000039511193,0.0000052417536,0.00014557912,0.00008673064,0.00079384376],"category_scores_gemma":[0.00022753014,0.000075851094,0.00009331981,0.00017439967,0.00034686565,0.000029851291,0.00008375277,0.00047478822,0.000051960276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065963756,0.00012740333,0.000051995677,0.000046197376,0.000089773814,0.000033111897,0.000067847956,0.00002417622,0.99118,0.0001724075,0.005023227,0.0025242374],"study_design_scores_gemma":[0.0013111843,0.00024299766,0.0006397074,0.000007946776,0.0001298439,0.00008078878,0.000043279444,0.002650294,0.97942,0.0002684375,0.015133913,0.000071589166],"about_ca_topic_score_codex":0.000017678609,"about_ca_topic_score_gemma":0.0000030938606,"teacher_disagreement_score":0.011759966,"about_ca_system_score_codex":0.000020808124,"about_ca_system_score_gemma":0.000091694164,"threshold_uncertainty_score":0.86920327},"labels":[],"label_agreement":null},{"id":"W2115751707","doi":"10.1124/mol.105.017558","title":"Reactive Oxygen Species Generation Is Involved in Epidermal Growth Factor Receptor Transactivation through the Transient Oxidization of Src Homology 2-Containing Tyrosine Phosphatase in Endothelin-1 Signaling Pathway in Rat Cardiac Fibroblasts","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":103,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Transactivation; Small interfering RNA; Chemistry; Protein tyrosine phosphatase; Tyrosine phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Phosphorylation; Epidermal growth factor receptor; Signal transduction; Reactive oxygen species; Molecular biology; Phosphatase; Cell biology; Cancer research; Biology; Biochemistry; Receptor; Transcription factor; Transfection","score_opus":0.017404700897984217,"score_gpt":0.23640634931465732,"score_spread":0.2190016484166731,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115751707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863757,0.002107091,0.008822052,0.00092113967,0.000556141,0.00094380905,0.00020064616,0.000020430021,0.000053023512],"genre_scores_gemma":[0.99775493,0.00010792771,0.00027135358,0.00086926034,0.00006132316,0.00016272973,0.0006945257,0.00003274352,0.00004522089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99676186,0.0014051306,0.000766616,0.00051271945,0.00007747144,0.00047618063],"domain_scores_gemma":[0.9992158,0.0002296287,0.00025979927,0.00015840448,0.00011974839,0.000016646938],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037844395,0.00030866842,0.0005697617,0.00030650495,0.0000916432,0.000009573771,0.0001917875,0.0003052466,0.00025018954],"category_scores_gemma":[0.00003071664,0.0002768717,0.000121895144,0.00047828126,0.00018425491,0.00024185865,0.000031475793,0.00045677004,0.000011389444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006582621,0.0002812005,0.00043005464,0.00002360785,0.000080012134,0.000044000717,0.0026900452,0.001908633,0.99167347,0.0018181484,0.00011822706,0.00027434694],"study_design_scores_gemma":[0.0034283276,0.0002734398,0.00095748366,0.000036385427,0.000030849507,0.0000041757253,0.0004360402,0.00008001843,0.99334747,0.0002996658,0.00086345954,0.00024271607],"about_ca_topic_score_codex":0.0006786811,"about_ca_topic_score_gemma":0.00019716963,"teacher_disagreement_score":0.0113792475,"about_ca_system_score_codex":0.00020937774,"about_ca_system_score_gemma":0.000113139526,"threshold_uncertainty_score":0.99996835},"labels":[],"label_agreement":null},{"id":"W2117445095","doi":"10.1124/mol.107.043893","title":"Conformational Rearrangements and Signaling Cascades Involved in Ligand-Biased Mitogen-Activated Protein Kinase Signaling through the β1-Adrenergic Receptor","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"University of California, Riverside; Javna Agencija za Raziskovalno Dejavnost RS","keywords":"Protein kinase A; Signal transduction; Cell biology; Mitogen-activated protein kinase; Receptor; Chemistry; Signaling proteins; Kinase; Adrenergic receptor; Biology; Biochemistry","score_opus":0.020950013695614784,"score_gpt":0.2639409871703835,"score_spread":0.24299097347476872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117445095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951383,0.001502987,0.0018986147,0.00030796204,0.00028959292,0.0007085284,0.000017925217,0.000021116191,0.00011498064],"genre_scores_gemma":[0.9964368,0.00015159955,0.0012496569,0.0013952355,0.00019651462,0.00018989173,0.00020113222,0.00004105433,0.00013813918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99791324,0.0003860998,0.00050941407,0.00048442188,0.00026257292,0.00044425298],"domain_scores_gemma":[0.9993187,0.00003582854,0.00020759032,0.00021017826,0.000127658,0.00010001718],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004193235,0.00030004024,0.00029230272,0.00008472062,0.00028297197,0.000034485227,0.00026820254,0.00023697813,0.00030998877],"category_scores_gemma":[0.000060467122,0.0002522796,0.000115692754,0.0002123513,0.00017708162,0.000021667238,0.00013515895,0.0002686234,0.000010128995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026650127,0.00006605267,0.00012592955,0.000022275352,0.00012743864,0.000051395895,0.00058809656,0.0013735554,0.99664026,0.00008876764,0.0005051809,0.00014456324],"study_design_scores_gemma":[0.0020685226,0.0001909005,0.000028092083,0.000027530661,0.000028470282,0.000027778113,0.00027969052,0.0003452403,0.9897261,0.0001058718,0.0068754717,0.0002963109],"about_ca_topic_score_codex":0.000079769605,"about_ca_topic_score_gemma":0.0000060934112,"teacher_disagreement_score":0.0069141225,"about_ca_system_score_codex":0.000036317713,"about_ca_system_score_gemma":0.00012242676,"threshold_uncertainty_score":0.99999297},"labels":[],"label_agreement":null},{"id":"W2117639173","doi":"10.1124/mol.62.2.225","title":"Insulin-Like Growth Factor-1–Induced Phosphorylation of Transcription Factor FKHRL1 Is Mediated by Phosphatidylinositol 3-Kinase/Akt Kinase and Role of This Pathway in Insulin-Like Growth Factor-1–Induced Survival of Cultured Hippocampal Neurons","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Protein kinase B; PI3K/AKT/mTOR pathway; Biology; Phosphorylation; Cancer research; Proto-Oncogene Proteins c-akt; Cell biology; Kinase; Signal transduction","score_opus":0.01522370085462609,"score_gpt":0.23954025297390866,"score_spread":0.22431655211928256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117639173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300104,0.0035203618,0.00030703997,0.00019553227,0.0007188645,0.0010715508,0.0010566938,0.00004121924,0.00008769084],"genre_scores_gemma":[0.9979536,0.0007963305,0.00010368459,0.00030679823,0.00004985443,0.000055281318,0.00061375805,0.00008822421,0.000032475986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959349,0.0006882405,0.0012146207,0.0009159684,0.0006795631,0.00056672766],"domain_scores_gemma":[0.9978995,0.000077844204,0.0006820229,0.0003948937,0.00068739924,0.00025836733],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021712163,0.0006268902,0.00083687674,0.00033552657,0.00008349455,0.000019243753,0.0004065017,0.00078838534,0.00038620832],"category_scores_gemma":[0.0001409486,0.00067763135,0.00028315597,0.00061613286,0.00025968184,0.00006708258,0.000079866026,0.0004267718,0.000005544499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006426863,0.0008214323,0.0045845616,0.00017720644,0.00023962345,0.00001033411,0.0016874647,0.000016716289,0.989623,0.00003609395,0.00028204298,0.0018788046],"study_design_scores_gemma":[0.005290471,0.0010084414,0.019971723,0.000030245135,0.000098928096,0.0000050364074,0.00010144323,0.00076833,0.9711139,0.00003280771,0.0010509231,0.0005277321],"about_ca_topic_score_codex":0.00037791659,"about_ca_topic_score_gemma":0.000048010104,"teacher_disagreement_score":0.018509114,"about_ca_system_score_codex":0.000104877945,"about_ca_system_score_gemma":0.00012612452,"threshold_uncertainty_score":0.9995675},"labels":[],"label_agreement":null},{"id":"W2117753128","doi":"10.1124/mol.105.012278","title":"Intracellular K+ Is Required for the Inactivation-Induced High-Affinity Binding of Cisapride to HERG Channels","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"hERG; Intracellular; Chemistry; Biophysics; Cisapride; Potassium channel; Pharmacology; Biochemistry; Biology","score_opus":0.020653200497693442,"score_gpt":0.31415766597337874,"score_spread":0.2935044654756853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117753128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9753919,0.00021476248,0.004505604,0.01809679,0.0005902692,0.0010568253,0.000011098941,0.00003449405,0.0000982334],"genre_scores_gemma":[0.9904843,0.000029371515,0.0008968939,0.007433858,0.00071386003,0.00020424735,0.00001855156,0.000028558563,0.00019035258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885845,0.00009685294,0.0002797447,0.00028802894,0.00012586173,0.00035103195],"domain_scores_gemma":[0.99915457,0.00024306365,0.000114468894,0.000242952,0.00014544286,0.000099482626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002646006,0.00015966322,0.00037465704,0.00012915718,0.00012301447,0.0000047263775,0.0001238927,0.0001412644,0.00019338007],"category_scores_gemma":[0.000117367556,0.00013005376,0.00018673323,0.00027656686,0.0000658581,0.000043336542,0.00006092098,0.00023243483,0.000043555596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072595134,0.00009690861,0.0000088443285,0.000026712474,0.00035491964,0.000061122366,0.00022878232,0.00084578956,0.9886017,0.00046566216,0.0039255745,0.004658077],"study_design_scores_gemma":[0.0017667892,0.0004935823,0.00015366927,0.000011525758,0.00027336687,0.00005462986,0.000029566305,0.0006526829,0.9894177,0.00012628226,0.0069005266,0.00011972516],"about_ca_topic_score_codex":0.000016538135,"about_ca_topic_score_gemma":8.670876e-7,"teacher_disagreement_score":0.015092384,"about_ca_system_score_codex":0.000093620845,"about_ca_system_score_gemma":0.000102516664,"threshold_uncertainty_score":0.53034383},"labels":[],"label_agreement":null},{"id":"W2118024111","doi":"10.1124/mol.58.2.373","title":"From Agonist To Antagonist: Fab Fragments of an Agonist-Like Monoclonal Anti-β<sub>2</sub>-Adrenoceptor Antibody Behave as Antagonists","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Agonist; Chemistry; Adenylyl cyclase; Monoclonal antibody; Receptor; Partial agonist; Molecular biology; Antibody; Biophysics; Biochemistry; Biology; Immunology","score_opus":0.00650766770309406,"score_gpt":0.2858949982614332,"score_spread":0.27938733055833914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118024111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940996,0.0005736661,0.0022269513,0.00022472776,0.0011544582,0.00071731757,0.00047796144,0.00005725766,0.0004680642],"genre_scores_gemma":[0.9908852,0.00034750334,0.0025300342,0.0027421014,0.0006680127,0.000083892926,0.0024002613,0.0001379694,0.00020501431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961629,0.00034804482,0.00076858024,0.00134003,0.00047965767,0.00090076675],"domain_scores_gemma":[0.99825436,0.000020839578,0.00024803684,0.0007047903,0.00019509932,0.0005768486],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002812841,0.0006328581,0.00069551566,0.000155173,0.0002994448,0.000092283735,0.0008076165,0.0004986156,0.003236547],"category_scores_gemma":[0.000016912205,0.00070612336,0.0003500949,0.00026043755,0.00024299041,0.000023744728,0.00024999186,0.00031956343,0.00023358612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006493303,0.000605687,0.00019994623,0.000022197637,0.0003557869,0.00028841692,0.0001671775,0.00062833086,0.98726577,0.000023315575,0.0014475293,0.008346528],"study_design_scores_gemma":[0.0019149076,0.0013375668,0.00038690533,0.000020413625,0.00019691479,0.00007471335,0.00007798318,0.00022704073,0.97028136,0.000119558965,0.024638835,0.00072380254],"about_ca_topic_score_codex":0.00028996888,"about_ca_topic_score_gemma":0.0000135855635,"teacher_disagreement_score":0.023191307,"about_ca_system_score_codex":0.00006231526,"about_ca_system_score_gemma":0.00027122727,"threshold_uncertainty_score":0.999539},"labels":[],"label_agreement":null},{"id":"W2118120337","doi":"10.1124/mol.110.064014","title":"Potassium Channel Block by a Tripartite Complex of Two Cationophilic Ligands and a Potassium Ion","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Chemistry; Potassium channel; Docking (animal); Ion channel; Selectivity; Stereochemistry; Helix (gastropod); Molecule; Biophysics; Potassium; Ligand-gated ion channel; Crystallography; Receptor; Biochemistry","score_opus":0.01065182238729112,"score_gpt":0.27744743618829276,"score_spread":0.26679561380100164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118120337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99513614,0.00024610158,0.0014998203,0.001316861,0.0011261983,0.00026147297,0.00004226553,0.000018955705,0.00035220312],"genre_scores_gemma":[0.9976061,0.000045460285,0.000103545965,0.0010335075,0.0004250931,0.00004837435,0.00034214518,0.000023855593,0.0003719476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998996,0.00006524743,0.00025343383,0.00034307686,0.00011062917,0.00023156907],"domain_scores_gemma":[0.99939907,0.0000124501685,0.00013962649,0.00018587268,0.0001374397,0.00012553585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017016403,0.00016719244,0.00017869237,0.00008898897,0.00008086995,0.000012031211,0.0001140817,0.0001807524,0.0000730587],"category_scores_gemma":[0.000026378613,0.00017336776,0.00007138578,0.00012210802,0.00015970241,0.0000054855113,0.00008280016,0.0001500883,0.000005800055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010678916,0.00011618082,0.0001331195,0.000015295214,0.0000539849,0.000003216303,0.00004757645,0.00012751976,0.9881153,0.00009997127,0.010928907,0.00025215428],"study_design_scores_gemma":[0.0020485905,0.00022439995,0.0005443254,0.0000017444252,0.000049883238,0.00006012964,0.000016767151,0.0028310977,0.9698662,0.000090093854,0.024094397,0.00017233373],"about_ca_topic_score_codex":0.000018662728,"about_ca_topic_score_gemma":0.0000078099765,"teacher_disagreement_score":0.018249048,"about_ca_system_score_codex":0.000007469633,"about_ca_system_score_gemma":0.00004617582,"threshold_uncertainty_score":0.70697325},"labels":[],"label_agreement":null},{"id":"W2119147817","doi":"10.1124/mol.64.5.1109","title":"Role of Mitochondrial Aldehyde Dehydrogenase in Nitrate Tolerance","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Aldehyde dehydrogenase; Propionaldehyde; ALDH2; Chemistry; Pharmacology; In vivo; Vasodilation; Enzyme; Biochemistry; Biology; Endocrinology; Acetaldehyde; Ethanol","score_opus":0.006065272289267709,"score_gpt":0.27337504526075845,"score_spread":0.2673097729714907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119147817","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910143,0.0019084578,0.00020155036,0.000112156595,0.0002989413,0.0004445134,0.0000032113044,0.000023092482,0.0059937737],"genre_scores_gemma":[0.99681735,0.000051965366,0.0014927188,0.0013701045,0.00007933352,0.000054665474,0.000004796165,0.000023549368,0.00010552804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884117,0.00020999741,0.00027148452,0.00023133685,0.00013280762,0.0003132066],"domain_scores_gemma":[0.99955165,0.00006190556,0.00006492494,0.00016119242,0.00004514332,0.00011517969],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013961626,0.00013758842,0.00033919959,0.00015751945,0.000015152903,0.0000022084052,0.0000740748,0.00010286025,0.00032566287],"category_scores_gemma":[0.00006938953,0.0001354669,0.000101732025,0.00029079724,0.00006102795,0.000026911972,0.00001508767,0.00020806665,0.00004815522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033390548,0.0002803162,0.0016249635,0.00004504828,0.00005845574,0.0005737207,0.00007238563,0.0002715256,0.9956927,0.00027831487,0.00029655272,0.0004721479],"study_design_scores_gemma":[0.0055137216,0.0001996214,0.00023276922,0.00001916468,0.00010053448,0.000113936614,0.000020859588,0.00044896107,0.9873399,0.00047338268,0.005428102,0.00010902787],"about_ca_topic_score_codex":0.00003083851,"about_ca_topic_score_gemma":0.0000047770604,"teacher_disagreement_score":0.008352744,"about_ca_system_score_codex":0.00003631796,"about_ca_system_score_gemma":0.00011525041,"threshold_uncertainty_score":0.55241793},"labels":[],"label_agreement":null},{"id":"W2119199396","doi":"10.1124/mol.108.048033","title":"Cross-Talk between Dopaminergic and Noradrenergic Systems in the Rat Ventral Tegmental Area, Locus Ceruleus, and Dorsal Hippocampus","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":142,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa","funders":"","keywords":"Idazoxan; Locus coeruleus; Ventral tegmental area; Dopaminergic; Neuroscience; Raclopride; Locus Ceruleus; Dopamine; Internal medicine; Autoreceptor; Chemistry; Rauwolscine; Dorsal raphe nucleus; Endocrinology; Inhibitory postsynaptic potential; Biology; Substantia nigra; Receptor; Antagonist; Serotonergic; Serotonin; Central nervous system; Prazosin; Medicine","score_opus":0.029829815388335953,"score_gpt":0.3001765881977884,"score_spread":0.27034677280945246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119199396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971148,0.0010346705,0.000018655604,0.00034246192,0.00061662623,0.0007229361,0.00003189316,0.00004786684,0.00007011253],"genre_scores_gemma":[0.99792236,0.00014295237,0.000011398453,0.0016017494,0.00007920537,0.00015281099,0.000005683404,0.000035670502,0.0000481839],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973618,0.0006020778,0.0003840072,0.0007032302,0.00034490373,0.0006040214],"domain_scores_gemma":[0.999303,0.00017035771,0.00010777545,0.00022500147,0.000018579669,0.00017531226],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019328688,0.00031637162,0.00033207404,0.00015558956,0.00023146808,0.000100286656,0.00044945598,0.000121914854,0.00006655924],"category_scores_gemma":[0.000025740652,0.0002605874,0.00006364585,0.0003244925,0.00085078756,0.0001601555,0.00011512456,0.00045272394,0.000014420229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004804668,0.000105240855,0.036947552,0.000023050561,0.0000067398323,0.0047917906,0.0002722923,0.00018867274,0.9567368,0.000027087513,0.000092842456,0.0007599007],"study_design_scores_gemma":[0.0040153223,0.00036061375,0.034631263,0.00001911872,0.00010027417,0.004719408,0.000044634562,0.00025839737,0.952579,0.000054243796,0.0026907213,0.00052698393],"about_ca_topic_score_codex":0.00010919609,"about_ca_topic_score_gemma":0.000002667376,"teacher_disagreement_score":0.004157767,"about_ca_system_score_codex":0.000055747823,"about_ca_system_score_gemma":0.000049388058,"threshold_uncertainty_score":0.9999846},"labels":[],"label_agreement":null},{"id":"W2119207863","doi":"10.1124/mol.105.017855","title":"Valproic Acid Increases Conservative Homologous Recombination Frequency and Reactive Oxygen Species Formation: A Potential Mechanism for Valproic Acid-Induced Neural Tube Defects","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacological Effects and Toxicity Studies","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Valproic Acid; Neural tube; Catalase; Homologous recombination; Reactive oxygen species; Chemistry; DNA damage; Biochemistry; Oxidative stress; Molecular biology; Cell biology; Biology; DNA; Embryo; Epilepsy","score_opus":0.02596673299447454,"score_gpt":0.3025998643366533,"score_spread":0.27663313134217876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119207863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833188,0.0008588931,0.003822993,0.008290758,0.00038655105,0.0026092166,0.00004252262,0.00016080936,0.00050947693],"genre_scores_gemma":[0.9879344,0.00014344374,0.0015176366,0.009192428,0.0003076192,0.0007046566,0.000087857305,0.00003567925,0.000076286204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99790674,0.00037043833,0.00040418486,0.0005331459,0.00023624937,0.0005492245],"domain_scores_gemma":[0.99875456,0.0002254898,0.00022770636,0.00013741016,0.0004276812,0.00022714664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003205997,0.0003749797,0.0006218274,0.000205282,0.0003584921,0.000030834843,0.00013408545,0.00021762212,0.00011668976],"category_scores_gemma":[0.00037732685,0.0003273384,0.00019803805,0.00022163063,0.00017697885,0.00029200478,0.00013986217,0.00037943167,0.000013829978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068761193,0.0005003521,0.00008206716,0.0001279129,0.0004446733,0.00032476505,0.0002328326,0.0000074565523,0.9928607,0.0017243293,0.00091704703,0.0020902976],"study_design_scores_gemma":[0.0076140845,0.0027501872,0.003751082,0.000024407733,0.000978885,0.0005465862,0.00011559958,0.0051474557,0.9740516,0.004460788,0.0002101893,0.00034912786],"about_ca_topic_score_codex":0.000028253378,"about_ca_topic_score_gemma":0.000010615063,"teacher_disagreement_score":0.018809047,"about_ca_system_score_codex":0.00024620682,"about_ca_system_score_gemma":0.00009160169,"threshold_uncertainty_score":0.99991786},"labels":[],"label_agreement":null},{"id":"W2119377931","doi":"10.1124/mol.110.069419","title":"Involvement of Caveolin in Probucol-Induced Reduction in hERG Plasma-Membrane Expression","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Queen's University","funders":"Canadian Institutes of Health Research; University of Kentucky; University of Wisconsin-Madison","keywords":"Probucol; hERG; Caveolin 1; Reduction (mathematics); Caveolin; Chemistry; Membrane; Caveolae; Expression (computer science); Caveolin 3; Cell biology; Pharmacology; Biochemistry; Biophysics; Biology; Computer science; Cholesterol; Mathematics; Potassium channel","score_opus":0.02132070415499948,"score_gpt":0.26472945199054876,"score_spread":0.24340874783554928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119377931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99755734,0.0005217036,0.00017235431,0.00004248638,0.00031014864,0.00045853478,0.0000033115045,0.000009810333,0.0009243034],"genre_scores_gemma":[0.9988875,0.00017717783,0.0004117944,0.000117917625,0.00007152965,0.00014352078,0.000049584236,0.000028370454,0.00011259991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852836,0.00015581722,0.00042111447,0.00044252424,0.00012520154,0.0003269983],"domain_scores_gemma":[0.999493,0.0000049491036,0.00014016648,0.00022006454,0.000070628324,0.000071166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025991965,0.0001920513,0.00024368905,0.00018914108,0.000021170978,0.0000034262325,0.00021956308,0.00024004187,0.00011889283],"category_scores_gemma":[0.000020300355,0.00020424902,0.00007494596,0.00022972145,0.00007296859,0.000007107234,0.00013924105,0.00018002964,0.0000057187385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045870544,0.00049465394,0.0011775406,0.000093375056,0.00002790312,0.00007765052,0.0003761559,0.00015755174,0.99647385,0.000026235795,0.00010060453,0.00053578045],"study_design_scores_gemma":[0.0021117304,0.00032045093,0.000586701,0.00002993249,0.00001904426,0.000028138655,0.00015358448,0.00008494506,0.9958814,0.000081987964,0.000502436,0.00019966808],"about_ca_topic_score_codex":0.00015882641,"about_ca_topic_score_gemma":0.00010300334,"teacher_disagreement_score":0.0016530249,"about_ca_system_score_codex":0.000034298842,"about_ca_system_score_gemma":0.00012612432,"threshold_uncertainty_score":0.8329033},"labels":[],"label_agreement":null},{"id":"W2119441209","doi":"10.1124/mol.115.098707","title":"Rotational Symmetry of Two Pyrethroid Receptor Sites in the Mosquito Sodium Channel","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Insect and Pesticide Research","field":"Agricultural and Biological Sciences","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Pyrethroid; Knockdown resistance; Deltamethrin; Transmembrane domain; Sodium channel; Linker; Stereochemistry; Helix (gastropod); Chemistry; Sodium; Receptor; Biology; Biochemistry; Pesticide","score_opus":0.05829028933775324,"score_gpt":0.33876772276389144,"score_spread":0.2804774334261382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119441209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929745,0.00038735772,0.000008058821,0.0037875418,0.00014028644,0.0002157122,0.000016020265,0.000010044392,0.0024604704],"genre_scores_gemma":[0.99848473,0.00001408208,0.000051098654,0.001108294,0.00020578559,0.000040243474,0.000055162378,8.433062e-7,0.00003975018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998802,0.00038239354,0.00015199791,0.00015147185,0.00026282616,0.00024928697],"domain_scores_gemma":[0.9994914,0.00025736136,0.00004493555,0.000032077383,0.00010992061,0.00006429094],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006591685,0.000080468264,0.00011864251,0.000023680112,0.000046363577,0.000012937726,0.00030928777,0.0000573509,0.00066174194],"category_scores_gemma":[0.00006534218,0.000030087087,0.00004839089,0.0003893813,0.00009936649,0.00003681966,0.00006298031,0.00016860041,0.00004883827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006189866,0.00010814405,0.001376092,0.0000045593415,0.000011000569,0.000023918348,0.00022356446,0.000045527875,0.9921915,0.0010678498,0.003525455,0.0013604709],"study_design_scores_gemma":[0.0018901809,0.0011601814,0.01889826,0.000012095031,0.000037231384,0.000036420304,0.0010524943,0.0017267829,0.94739074,0.01488374,0.012566163,0.00034570825],"about_ca_topic_score_codex":0.00024720325,"about_ca_topic_score_gemma":0.000089137044,"teacher_disagreement_score":0.044800777,"about_ca_system_score_codex":0.000021129108,"about_ca_system_score_gemma":0.000028223636,"threshold_uncertainty_score":0.72456104},"labels":[],"label_agreement":null},{"id":"W2120067620","doi":"10.1124/mol.108.053389","title":"AMD3100 Is a CXCR7 Ligand with Allosteric Agonist Properties","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":312,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Allosteric regulation; Agonist; Receptor; Chemistry; Arrestin; Cell biology; Chemokine receptor; G protein-coupled receptor; In vivo; Ligand (biochemistry); Signal transduction; Biophysics; Chemokine; Biochemistry; Biology; Genetics","score_opus":0.013962362794129915,"score_gpt":0.2733190178079958,"score_spread":0.25935665501386584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120067620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843051,0.0012170408,0.00036691237,0.010810593,0.00010182237,0.0003628405,0.0000014501321,0.000071828115,0.0027624466],"genre_scores_gemma":[0.9804922,0.00005686075,0.00045517573,0.017725695,0.00017300237,0.000019031026,0.0000085988395,0.000023492672,0.0010459532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990505,0.000030931842,0.00016879168,0.00027515364,0.00017257972,0.00030206813],"domain_scores_gemma":[0.9995812,0.0000065782538,0.000050548413,0.00013908136,0.000080842285,0.0001417359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064306,0.00017622962,0.0002970024,0.000071486975,0.0000637747,0.000019215642,0.00007889525,0.00007681361,0.00033134],"category_scores_gemma":[0.000005463401,0.00012771945,0.00008020995,0.00016677726,0.00007759285,0.000032556356,0.000023435123,0.00019148685,0.00004311122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045467025,0.00017486139,0.00025719352,0.00003934874,0.00011901472,0.0005306346,0.0002469015,0.000011501584,0.99021024,0.0000138424875,0.0050198287,0.002921986],"study_design_scores_gemma":[0.0023406819,0.00095473655,0.00021330747,0.000044741617,0.00024985985,0.00036140718,0.000022181739,0.00029259242,0.96677727,0.000022524335,0.028553542,0.00016715487],"about_ca_topic_score_codex":0.000008286807,"about_ca_topic_score_gemma":4.3035604e-7,"teacher_disagreement_score":0.023533713,"about_ca_system_score_codex":0.000046691075,"about_ca_system_score_gemma":0.000097315686,"threshold_uncertainty_score":0.52082485},"labels":[],"label_agreement":null},{"id":"W2120111690","doi":"10.1124/mol.110.068031","title":"Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Stereochemistry; Side chain; Moiety; Helix (gastropod); Cav1.2; Mutant; Crystallography; Protein subunit; Biochemistry","score_opus":0.013808143498296137,"score_gpt":0.2511526823779547,"score_spread":0.23734453887965853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120111690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987058,0.0011762152,0.0062151495,0.002354645,0.0018644556,0.0005359292,0.000090423375,0.000027654394,0.0006775711],"genre_scores_gemma":[0.98978806,0.0001884898,0.000033573535,0.008168684,0.00026245744,0.0000992842,0.00026430452,0.000035820834,0.0011593532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985339,0.00024402079,0.000321815,0.0003742442,0.00021813934,0.0003078626],"domain_scores_gemma":[0.99918926,0.000025409021,0.00021107141,0.00032028343,0.00018305045,0.00007095073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029572137,0.00022538344,0.00017947376,0.0000804123,0.00018989669,0.0000150099795,0.00036306574,0.00021698722,0.00016062723],"category_scores_gemma":[0.000027165426,0.00013920064,0.00013772029,0.00025867327,0.00026085853,0.000009087971,0.00012384687,0.00018390012,0.000010537999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004294643,0.0001254287,0.00003085156,0.000012743739,0.00016367591,0.0000037752231,0.00020599144,0.00017899444,0.9114918,0.000040022587,0.08683532,0.00048193027],"study_design_scores_gemma":[0.0014771466,0.0002489241,0.000103130515,0.0000023524187,0.00008086126,0.000022805743,0.00019181559,0.00070251524,0.92105186,0.000049040536,0.07589578,0.00017375701],"about_ca_topic_score_codex":0.00013424733,"about_ca_topic_score_gemma":0.000009168448,"teacher_disagreement_score":0.010939541,"about_ca_system_score_codex":0.000018457604,"about_ca_system_score_gemma":0.000041270097,"threshold_uncertainty_score":0.5676437},"labels":[],"label_agreement":null},{"id":"W2120396533","doi":"10.1016/s0026-895x(24)12610-7","title":"Glutathione Peroxidase-1 Overexpression Prevents Ceramide Production and Partially Inhibits Apoptosis in Doxorubicin-Treated Human Breast Carcinoma Cells","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":152,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Ceramide; Programmed cell death; Glutathione peroxidase; Glutathione; Biology; Apoptosis; Cancer cell; Reactive oxygen species; Sphingomyelin; GPX4; Doxorubicin; Cancer research; Cell biology; Molecular biology; Biochemistry; Cancer; Enzyme","score_opus":0.010874393323507887,"score_gpt":0.2529061589754913,"score_spread":0.2420317656519834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120396533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972081,0.0005525519,0.00009194824,0.0005334737,0.00050192216,0.00082063733,0.000026385049,0.000089171815,0.00017580195],"genre_scores_gemma":[0.9980678,0.000119237404,0.00004835102,0.00056069973,0.00007231284,0.000119480734,0.00012547271,0.00004793204,0.00083872303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971696,0.000813462,0.00046779832,0.0008092061,0.00007548152,0.0006644657],"domain_scores_gemma":[0.9993705,0.00003313051,0.00017035443,0.00026049855,0.00008620065,0.0000792781],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025728936,0.00038771052,0.0004587926,0.00030963004,0.00025825034,0.00001915254,0.00019493488,0.00032829205,0.0004894791],"category_scores_gemma":[0.00001395435,0.00037350936,0.000084863204,0.0003196187,0.00021115107,0.00017552059,0.00020458241,0.00048668685,0.00011784744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044480083,0.0010989862,0.0022505883,0.000030560015,0.00010813688,0.00012145391,0.0002333014,0.00003105553,0.99383515,0.00011008311,0.0006459752,0.0010898903],"study_design_scores_gemma":[0.00537517,0.0003225786,0.003623772,0.000086846216,0.00010848485,0.00029277295,0.00007990135,0.000008507591,0.98899597,0.00014655902,0.00060197513,0.000357448],"about_ca_topic_score_codex":0.0001736509,"about_ca_topic_score_gemma":0.000025764453,"teacher_disagreement_score":0.0049303696,"about_ca_system_score_codex":0.00010396475,"about_ca_system_score_gemma":0.000040734554,"threshold_uncertainty_score":0.9998717},"labels":[],"label_agreement":null},{"id":"W2120887281","doi":"10.1124/mol.111.072504","title":"Batrachotoxin, Pyrethroids, and BTG 502 Share Overlapping Binding Sites on Insect Sodium Channels","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Batrachotoxin; Chemistry; Sodium channel; Stereochemistry; Helix (gastropod); Pyrethroid; Binding site; Gating; Sodium; Crystallography; Biophysics; Biochemistry; Biology","score_opus":0.03816652952709572,"score_gpt":0.27079801317982555,"score_spread":0.23263148365272984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120887281","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936492,0.00044783717,0.0016339938,0.00019206529,0.0014254814,0.00031085042,0.00002021004,0.000045893292,0.002274465],"genre_scores_gemma":[0.99629194,0.0001149411,0.00018161764,0.00203368,0.0005824688,0.000055411623,0.00021401324,0.00004059454,0.0004853099],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987024,0.00012469513,0.00020660684,0.0005040517,0.000120933386,0.00034128],"domain_scores_gemma":[0.99948555,0.000015941845,0.00009501019,0.00017671754,0.00009266312,0.00013410152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016989368,0.0002320236,0.00017432799,0.00014489937,0.00014675428,0.000024353658,0.000133055,0.00024587553,0.00048695304],"category_scores_gemma":[0.000057251666,0.00024069966,0.00009192928,0.00012042462,0.000097127166,0.000009906539,0.000111866066,0.0001703801,0.00004489506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022520674,0.00007963464,0.00047766336,0.000022131842,0.00009057772,0.000030888124,0.0001724394,0.00007754135,0.99400985,0.00015550152,0.004013183,0.0006453807],"study_design_scores_gemma":[0.0011408231,0.00053676596,0.00094633026,0.000009673469,0.000039770915,0.00004319796,0.000067078865,0.0008555904,0.9817269,0.000093231574,0.014242307,0.00029833836],"about_ca_topic_score_codex":0.0000093040435,"about_ca_topic_score_gemma":0.00000169965,"teacher_disagreement_score":0.01228296,"about_ca_system_score_codex":0.00002181736,"about_ca_system_score_gemma":0.0000315354,"threshold_uncertainty_score":0.98154473},"labels":[],"label_agreement":null},{"id":"W2121551257","doi":"10.1124/mol.63.4.821","title":"Unexpected Induction of the Human Connexin 43 Promoter by the Ras Signaling Pathway Is Mediated by a Novel Putative Promoter Sequence","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Molecular biology; Biology; Promoter; Transcription factor; Signal transduction; Kinase; Transcription (linguistics); Transcriptional regulation; Gene; Cell biology; Gene expression; Biochemistry","score_opus":0.019697872906206615,"score_gpt":0.2861588377911386,"score_spread":0.266460964884932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121551257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946505,0.0006838091,0.0017431275,0.0014586732,0.00024732633,0.00074535585,0.0001898007,0.000015087842,0.00026635066],"genre_scores_gemma":[0.9959514,0.000013366306,0.000081473416,0.0032124387,0.000054073356,0.0001173249,0.00020950814,0.00003480555,0.00032558842],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978448,0.00070599705,0.00037569582,0.00052943244,0.00015122455,0.0003928101],"domain_scores_gemma":[0.99908495,0.00003825014,0.00027517675,0.00034045614,0.00019199184,0.00006919317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036332937,0.00027315613,0.00024866522,0.000038629005,0.0001882021,0.000014042498,0.0003909652,0.0003059886,0.0002083032],"category_scores_gemma":[0.000104063365,0.00018164144,0.00014568027,0.0002346915,0.0004937502,0.0000056273193,0.00012575764,0.00031401071,0.000004939629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004257148,0.00018010272,0.00012465501,0.000010660452,0.00022219439,0.0000046110504,0.00033980035,0.000014031284,0.99527764,0.00013957755,0.0034486705,0.00019547105],"study_design_scores_gemma":[0.0013402974,0.00032615653,0.00003467137,0.0000060770562,0.00006203904,0.000048296053,0.00011688209,0.000047816615,0.9618739,0.000110718545,0.035817973,0.00021518125],"about_ca_topic_score_codex":0.0000472249,"about_ca_topic_score_gemma":0.000006001197,"teacher_disagreement_score":0.033403765,"about_ca_system_score_codex":0.000031555373,"about_ca_system_score_gemma":0.00013485043,"threshold_uncertainty_score":0.74071234},"labels":[],"label_agreement":null},{"id":"W2121766795","doi":"10.1124/mol.107.036418","title":"Inhibition of Hypoxia-Induced Increase of Blood-Brain Barrier Permeability by YC-1 through the Antagonism of HIF-1α Accumulation and VEGF Expression","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":145,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Council Canada","keywords":"Tight junction; Hypoxia (environmental); Blood–brain barrier; Chemistry; Fluorescein isothiocyanate; Cell biology; Permeability (electromagnetism); Ischemia; Dextran; Pharmacology; Vascular permeability; Occludin; Vascular endothelial growth factor; Biology; Biochemistry; Endocrinology; Internal medicine; Cancer research; VEGF receptors; Medicine; Central nervous system; Oxygen","score_opus":0.028724143079717816,"score_gpt":0.32254777526388867,"score_spread":0.29382363218417085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121766795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967798,0.000267951,0.0014442924,0.00034337517,0.00025673292,0.0003383474,0.00005329952,0.000015623,0.000500564],"genre_scores_gemma":[0.9986815,0.00003088659,0.0000975643,0.0011141453,0.00003677617,0.000010655346,0.000005655405,0.000011261504,0.000011583016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984487,0.00037458463,0.00043229753,0.00031402227,0.0002381694,0.00019217673],"domain_scores_gemma":[0.99892306,0.00042208805,0.00030277253,0.00019814618,0.00010061219,0.0000533213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040327432,0.00014496718,0.00026847702,0.0000634323,0.00013085234,0.0000043164296,0.00010839666,0.00011384211,0.000074954936],"category_scores_gemma":[0.0003290472,0.00011058069,0.00007272247,0.00024480038,0.0004646832,0.00011574728,0.00013103537,0.00016565232,4.6152647e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023497475,0.00009893989,0.000423361,0.000044285476,0.000024205681,0.000008141771,0.0009858208,0.000011910763,0.9971262,0.0002527243,0.00041067076,0.00037875638],"study_design_scores_gemma":[0.0012216703,0.00018251648,0.0023704066,0.000007714254,0.00010255894,0.00001310703,0.00017557679,0.000059667975,0.99449205,0.0008908434,0.00039454858,0.00008932092],"about_ca_topic_score_codex":0.00005774119,"about_ca_topic_score_gemma":0.0000017602553,"teacher_disagreement_score":0.0026341397,"about_ca_system_score_codex":0.000010053484,"about_ca_system_score_gemma":0.00003067002,"threshold_uncertainty_score":0.45093495},"labels":[],"label_agreement":null},{"id":"W2122146139","doi":"10.1124/mol.58.1.120","title":"Inhibition of Cell Surface Expression by Mutant Receptors Demonstrates that D2 Dopamine Receptors Exist as Oligomers in the Cell","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Mutant; Receptor; Cell biology; Wild type; 5-HT5A receptor; Biology; Dopamine receptor; G protein-coupled receptor; HEK 293 cells; Cell; Gene; Biochemistry; Chemistry","score_opus":0.0072587969378901844,"score_gpt":0.24378114250998295,"score_spread":0.23652234557209276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122146139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925024,0.0014393922,0.00034498778,0.00014728558,0.00033786893,0.000420563,0.00002086363,0.000013570111,0.0047730654],"genre_scores_gemma":[0.996706,0.0011739419,0.00056556263,0.0006272249,0.000062313586,0.000036922593,0.00023673647,0.000041313302,0.000549951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979378,0.00049955543,0.00038723822,0.0005030603,0.00024530504,0.00042707068],"domain_scores_gemma":[0.99939626,0.000035803343,0.00017058753,0.00025144964,0.000047273836,0.00009860806],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041559272,0.00029091732,0.00026724656,0.000059028174,0.000090988,0.000020154477,0.00031186233,0.00028085735,0.0024960188],"category_scores_gemma":[0.0000083444975,0.00024397076,0.000143049,0.0001709209,0.00014278645,0.000010603916,0.00005956388,0.0002448732,0.00003523311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017858428,0.00026357142,0.000102997765,0.000029294744,0.00001728975,0.000026814796,0.00017032167,0.00071977405,0.99435985,0.000007184567,0.0035824936,0.0005418296],"study_design_scores_gemma":[0.0011597394,0.0004234448,0.0000052789383,0.000018475272,0.00003428537,0.00001400516,0.00047050466,0.000040773055,0.9827281,0.00004755826,0.014795331,0.00026246437],"about_ca_topic_score_codex":0.000057440386,"about_ca_topic_score_gemma":0.000003095415,"teacher_disagreement_score":0.011631705,"about_ca_system_score_codex":0.000026374446,"about_ca_system_score_gemma":0.000060353475,"threshold_uncertainty_score":0.9984158},"labels":[],"label_agreement":null},{"id":"W2123241015","doi":"10.1124/mol.106.033563","title":"Insulin Increases the Potency of Glycine at Ionotropic Glycine Receptors","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Glycine receptor; Insulin receptor; Ionotropic effect; Homomeric; Wortmannin; Biology; Insulin receptor substrate; Internal medicine; Endocrinology; Receptor; Glycine; Insulin; Phosphatidylinositol; Cell biology; Biochemistry; Signal transduction; NMDA receptor; Protein subunit; Amino acid; Medicine; Insulin resistance","score_opus":0.027529988354259103,"score_gpt":0.34091475905671387,"score_spread":0.31338477070245474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123241015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935087,0.00036600197,0.00018967869,0.0026226495,0.001324802,0.0006156421,0.000010952078,0.0000760425,0.0012855602],"genre_scores_gemma":[0.9877188,0.0005368463,0.00002581637,0.01044517,0.00015590913,0.000033659868,0.0000013254311,0.000035024124,0.0010474499],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99660003,0.0007940181,0.0005133121,0.00069640693,0.00054674415,0.000849501],"domain_scores_gemma":[0.9981491,0.00092195946,0.00021173242,0.00037675683,0.00009884506,0.00024159146],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00068759575,0.00025699302,0.00032042345,0.0002928322,0.0003886909,0.0000136010785,0.0010286547,0.00010659071,0.0010994535],"category_scores_gemma":[0.00061249017,0.00018914402,0.00014005732,0.0011866802,0.0011789403,0.00011028858,0.0005879223,0.0005315685,0.00019363746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006676028,0.0003250905,0.0006495503,0.000015557724,0.000011038449,0.00094443903,0.000050614784,0.000049402694,0.99173576,0.0003156223,0.0031052404,0.002130111],"study_design_scores_gemma":[0.0016417783,0.0005356457,0.0012847558,0.0000039689667,0.00004567002,0.00023812987,0.00001114061,0.00012704048,0.97460145,0.00009678294,0.021254178,0.00015948052],"about_ca_topic_score_codex":0.000045204728,"about_ca_topic_score_gemma":0.0000061068927,"teacher_disagreement_score":0.018148938,"about_ca_system_score_codex":0.00007973797,"about_ca_system_score_gemma":0.00011062291,"threshold_uncertainty_score":0.9998137},"labels":[],"label_agreement":null},{"id":"W2123746816","doi":"10.1124/mol.108.054254","title":"Functional Characterization and In Silico Docking of Full and Partial GluK2 Kainate Receptor Agonists","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Kainate receptor; Partial agonist; Kainic acid; Agonist; Ionotropic glutamate receptor; Ionotropic effect; AMPA receptor; Docking (animal); Chemistry; Glutamate receptor; Stereochemistry; Receptor; Biochemistry","score_opus":0.028316358729582262,"score_gpt":0.32322010319349137,"score_spread":0.2949037444639091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123746816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99680036,0.000048130405,0.0002254771,0.0021922095,0.00036591123,0.00028595742,0.000008072153,0.000024308105,0.000049588412],"genre_scores_gemma":[0.99596035,0.000287237,0.000008949892,0.0036122876,0.000047493682,0.000019515357,0.000002123829,0.000009551221,0.000052503594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830455,0.00041612278,0.00023346924,0.00049881084,0.00019373123,0.0003533474],"domain_scores_gemma":[0.99957824,0.00011599713,0.0000881211,0.00007983334,0.000029964036,0.00010787242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021706951,0.00013150573,0.00018902814,0.00022681316,0.000110889174,0.00002410443,0.00013612874,0.00006815539,0.00010103308],"category_scores_gemma":[0.000112006936,0.00013581505,0.000025258249,0.00037740005,0.00033818203,0.00016884056,0.000097269185,0.00026322808,0.000007967045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036963832,0.00012618347,0.000560714,0.000011820946,0.0000019130969,0.00018708539,0.000053415395,0.000046559788,0.9953789,0.00022208666,0.000044007425,0.0029976522],"study_design_scores_gemma":[0.0011190668,0.00032532867,0.008980582,0.0000043962555,0.0000093066565,0.00009805595,0.0000025813367,0.002942312,0.9852819,0.000048264217,0.0010826902,0.000105509906],"about_ca_topic_score_codex":0.0000012325207,"about_ca_topic_score_gemma":2.0728604e-7,"teacher_disagreement_score":0.010097017,"about_ca_system_score_codex":0.000017419567,"about_ca_system_score_gemma":0.000047115536,"threshold_uncertainty_score":0.5538377},"labels":[],"label_agreement":null},{"id":"W2124322010","doi":"10.1124/mol.113.088229","title":"Hepatocyte Nuclear Factors 4α and 1α Regulate Kidney Developmental Expression of Drug-Metabolizing Enzymes and Drug Transporters","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; University of California, San Diego","keywords":"Drug; Transporter; Hepatocyte; Drug metabolism; Hepatocyte nuclear factors; Enzyme; Biology; Drug development; Kidney; Cell biology; ATP-binding cassette transporter; Pharmacology; Biochemistry; Chemistry; Gene expression; Genetics; Gene; In vitro","score_opus":0.00592831726574876,"score_gpt":0.2232605905534695,"score_spread":0.21733227328772073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124322010","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99675095,0.0011930069,0.00014444416,0.000793402,0.0002074716,0.000560817,0.000011681704,0.000053213065,0.00028503104],"genre_scores_gemma":[0.9956106,0.00033540683,0.0025520807,0.0010963954,0.000021021388,0.00002147495,0.000032668693,0.00004351223,0.0002868314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987804,0.000056486613,0.00032281512,0.00034353184,0.00018779283,0.00030893032],"domain_scores_gemma":[0.99939096,0.00001674533,0.000094941584,0.00009883709,0.000048083355,0.00035045532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010767415,0.00023181003,0.0004407649,0.00014015211,0.00008609791,0.000009771129,0.000079395366,0.00009195355,0.00047261146],"category_scores_gemma":[0.0000044561316,0.00019193534,0.00008136082,0.000098469296,0.00018694147,0.00010307115,0.000030396195,0.00016959627,0.000004663363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014443722,0.0000720604,0.0065914895,0.00018670471,0.00010209625,0.000108403896,0.0019305664,0.0000010816218,0.9889044,0.000093180475,0.0011900839,0.0006754592],"study_design_scores_gemma":[0.0025389574,0.000039777624,0.018270722,0.00010570148,0.00023520399,0.000030471774,0.0007200042,0.000058833517,0.9710747,0.000053012718,0.00666917,0.00020342071],"about_ca_topic_score_codex":0.00005337322,"about_ca_topic_score_gemma":0.0000025051606,"teacher_disagreement_score":0.017829712,"about_ca_system_score_codex":0.000022052274,"about_ca_system_score_gemma":0.00006270559,"threshold_uncertainty_score":0.78268963},"labels":[],"label_agreement":null},{"id":"W2124351487","doi":"10.1124/mol.111.076745","title":"Regulation of Breast Cancer Resistant Protein by Peroxisome Proliferator-Activated Receptor α in Human Brain Microvessel Endothelial Cells","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Abcg2; Peroxisome proliferator-activated receptor; P-glycoprotein; Biology; Blood–brain barrier; Small interfering RNA; Cell biology; ATP-binding cassette transporter; Chromatin immunoprecipitation; Pharmacology; Clofibrate; Receptor; Chemistry; Cancer research; Transfection; Biochemistry; Transporter; Endocrinology; Gene expression; Promoter; Multiple drug resistance; Central nervous system","score_opus":0.006826322752693089,"score_gpt":0.2714953755063484,"score_spread":0.2646690527536553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124351487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99578744,0.00047148974,0.00015371376,0.0016932416,0.00027043442,0.0012025179,0.00021352181,0.00003901748,0.00016859242],"genre_scores_gemma":[0.9974511,0.000017549495,0.0002995036,0.00057830755,0.00015755945,0.00021097247,0.000092500675,0.00005162749,0.0011408245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845505,0.00015963455,0.00041768473,0.00027796417,0.00022745131,0.00046220442],"domain_scores_gemma":[0.99940604,0.000012822789,0.00016625208,0.00015847587,0.00009340485,0.00016299885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027292,0.00021074689,0.00040574698,0.00015751782,0.000047636964,0.000004527947,0.0001007585,0.00017728163,0.0008734096],"category_scores_gemma":[0.000004360848,0.00019539557,0.000089005174,0.00025731075,0.00010120775,0.00008544013,0.000017607985,0.00024183461,0.000006817712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014480229,0.0006859603,0.00063541846,0.00022784059,0.0000950996,0.000019766816,0.0002472876,0.0000057066236,0.9941756,0.0001972659,0.0021277913,0.00013422624],"study_design_scores_gemma":[0.0035869624,0.00013207755,0.0033531075,0.00010115269,0.00007696511,0.0000069085427,0.00003512622,0.000007744027,0.9862419,0.000023097507,0.0062538944,0.00018108821],"about_ca_topic_score_codex":0.00008870129,"about_ca_topic_score_gemma":0.000009286989,"teacher_disagreement_score":0.007933738,"about_ca_system_score_codex":0.00016256573,"about_ca_system_score_gemma":0.00011555791,"threshold_uncertainty_score":0.9563223},"labels":[],"label_agreement":null},{"id":"W2124444513","doi":"10.1124/mol.109.055608","title":"A Small-Molecule Modulator Interacts Directly with ΔPhe508-CFTR to Modify Its ATPase Activity and Conformational Stability","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Potentiator; Cystic fibrosis transmembrane conductance regulator; Endoplasmic reticulum; Chemistry; Mutant; Chloride channel; Cystic fibrosis; Transmembrane protein; Protease; Mutation; Trypsin; Biochemistry; Cell biology; Biophysics; Enzyme; Biology; Receptor; Gene","score_opus":0.023527058164312668,"score_gpt":0.3315306701389281,"score_spread":0.30800361197461545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124444513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98710203,0.0002677623,0.0059188344,0.0043307063,0.000066711335,0.0011778392,0.00003233788,0.00006154892,0.0010421987],"genre_scores_gemma":[0.9934681,0.000016810023,0.003331332,0.0029394734,0.000049836864,0.000090557296,0.000022185337,0.000019553861,0.000062154926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833107,0.00014252025,0.00022633042,0.00044394284,0.00036624097,0.00048991723],"domain_scores_gemma":[0.99874663,0.00012017685,0.000071488874,0.00022670702,0.00027613406,0.0005588703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017875308,0.00023574417,0.0003761843,0.0001621544,0.00008157681,0.000032573997,0.00012221892,0.00007575856,0.00032669783],"category_scores_gemma":[0.00024148847,0.00020334277,0.000056675464,0.00026856991,0.00011324519,0.00016744783,0.00009666309,0.00033253263,0.000042861484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029329725,0.00034873464,0.000119503406,0.00007666143,0.000092135975,0.00029607187,0.00018567099,0.00016295453,0.9855537,0.00009618914,0.00019173205,0.009943711],"study_design_scores_gemma":[0.0030760465,0.0017940145,0.016354268,0.000042058346,0.00008553967,0.0001581101,0.000022588587,0.008106436,0.96861094,0.00004687878,0.0014793499,0.00022375183],"about_ca_topic_score_codex":0.000020244961,"about_ca_topic_score_gemma":0.000010377977,"teacher_disagreement_score":0.016942706,"about_ca_system_score_codex":0.00016367402,"about_ca_system_score_gemma":0.00021316078,"threshold_uncertainty_score":0.8292078},"labels":[],"label_agreement":null},{"id":"W2124732042","doi":"10.1124/mol.110.068486","title":"Different Effects of the Different Natural CC Chemokine Receptor 2b Ligands on β-Arrestin Recruitment, Gαi Signaling, and Receptor Internalization","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Arrestin; CCR2; Agonist; Internalization; G protein-coupled receptor; Receptor; C-C chemokine receptor type 6; Endogenous agonist; Biology; Cell biology; Chemokine receptor; Chemistry; Chemokine; Pharmacology; Biochemistry; Dopamine receptor D1","score_opus":0.006969557832211784,"score_gpt":0.2585647412881634,"score_spread":0.25159518345595167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124732042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99292696,0.00052095327,0.0017544333,0.00037604722,0.0035788098,0.00077289017,0.000010955313,0.00001873912,0.000040221683],"genre_scores_gemma":[0.9978201,0.00016143826,0.0002263455,0.00093220297,0.00036988655,0.00013257547,0.000082380495,0.00004721139,0.00022786444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984635,0.00018652466,0.00032467087,0.00049128203,0.00021574408,0.00031826287],"domain_scores_gemma":[0.9991893,0.000057311627,0.00023814439,0.00030265137,0.00009015942,0.00012243445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015305144,0.0003277729,0.00030661546,0.000066029526,0.00010576616,0.000024152989,0.0003392591,0.00024389735,0.00020828398],"category_scores_gemma":[0.00012087437,0.00022890233,0.0001728154,0.000089422654,0.00013485021,0.0000043936084,0.00024331633,0.00040304303,0.0000037108757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019492245,0.00037289844,0.0005789382,0.00006731394,0.00014558302,0.0000031081695,0.00006213127,0.000007949023,0.99546456,0.0002719041,0.00095387787,0.0018768334],"study_design_scores_gemma":[0.002644549,0.0005176249,0.00029797503,0.000057826706,0.000084582214,0.000006344978,0.000007552289,0.00015454055,0.9896956,0.00008908236,0.0062050545,0.00023928186],"about_ca_topic_score_codex":0.000005214165,"about_ca_topic_score_gemma":0.000004915001,"teacher_disagreement_score":0.0057689543,"about_ca_system_score_codex":0.000022585697,"about_ca_system_score_gemma":0.00002647136,"threshold_uncertainty_score":0.9334366},"labels":[],"label_agreement":null},{"id":"W2125937217","doi":"10.1124/mol.106.032086","title":"Characterization and Comparison of Nicotine and Cotinine Metabolism in Vitro and in Vivo in DBA/2 and C57BL/6 Mice","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Cotinine; Nicotine; Metabolite; In vivo; Chemistry; Metabolism; In vitro; Enzyme; Pharmacology; Biochemistry; Internal medicine; Biology; Medicine","score_opus":0.005562708117916196,"score_gpt":0.2752759428788215,"score_spread":0.2697132347609053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125937217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99418265,0.0049191536,0.00014720093,0.00024873394,0.00006950475,0.00035903967,0.00001994347,0.0000041437092,0.000049654012],"genre_scores_gemma":[0.99858123,0.0006731956,0.00036731124,0.00018938222,0.000046939138,0.000025081335,0.0000641794,0.000019064204,0.000033637407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986895,0.00020357597,0.00040873556,0.0004007109,0.000064200976,0.00023332938],"domain_scores_gemma":[0.999681,0.000026937356,0.00013100453,0.00008390574,0.000027995022,0.00004915743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024824543,0.00017770295,0.00040172559,0.00015895994,0.00001749356,0.000008497544,0.000062344305,0.00015469256,0.0000069917137],"category_scores_gemma":[0.000027956186,0.00019415264,0.000015872974,0.00014883603,0.00014923839,0.000007988561,0.000186966,0.00015192918,1.4663226e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025367385,0.00018888747,0.06035383,0.000040698724,0.0000167384,0.0000026312723,0.00009801088,0.00001704052,0.9382059,0.000016019992,0.00003298656,0.00077358884],"study_design_scores_gemma":[0.0037795063,0.00008933153,0.05058961,0.000010237129,0.000030390464,0.000017590519,0.000040380703,0.00075651077,0.9429253,0.000008818152,0.0015941922,0.00015817992],"about_ca_topic_score_codex":0.00015223994,"about_ca_topic_score_gemma":0.00017855226,"teacher_disagreement_score":0.00976422,"about_ca_system_score_codex":0.000009414126,"about_ca_system_score_gemma":0.000021916467,"threshold_uncertainty_score":0.7917315},"labels":[],"label_agreement":null},{"id":"W2126014219","doi":"10.1124/mol.105.013573","title":"Capsaicin Regulates Voltage-Dependent Sodium Channels by Altering Lipid Bilayer Elasticity","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":210,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; Ryerson University","keywords":"Capsazepine; Bilayer; Chemistry; Biophysics; Capsaicin; Lipid bilayer; Sodium channel; Biochemistry; TRPV1; Membrane; Transient receptor potential channel; Sodium; Receptor; Biology","score_opus":0.015632715855994257,"score_gpt":0.2751178509325326,"score_spread":0.25948513507653836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126014219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98451495,0.00027228054,0.006983777,0.0025464543,0.0043331007,0.00041224106,0.00002390235,0.00020594792,0.00070735684],"genre_scores_gemma":[0.99047166,0.00008926307,0.000059145248,0.0056302315,0.0009631342,0.00006155856,0.00000567981,0.00005952522,0.0026597893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976415,0.00022757483,0.00034740794,0.0007155613,0.00031600377,0.00075194135],"domain_scores_gemma":[0.9993453,0.00008870102,0.00012967612,0.00015232143,0.00004519877,0.0002387825],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019785452,0.0003106172,0.00029890117,0.00014738161,0.00022929294,0.000053206644,0.00042465748,0.00016946909,0.0014037661],"category_scores_gemma":[0.0000637535,0.00028533023,0.00012471656,0.00022250801,0.0001722901,0.00014431901,0.00021955463,0.00035717373,0.00049741834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045659614,0.0001777909,0.0000040044183,0.000014732504,0.00001729362,0.00007956648,0.00015729996,0.005800414,0.9745544,0.000062641295,0.01736093,0.0017252278],"study_design_scores_gemma":[0.000896401,0.000106594234,0.0000025112938,0.0000067510177,0.000032899705,0.00005788519,0.000011206552,0.013133679,0.9416629,0.000041131745,0.043742042,0.00030596793],"about_ca_topic_score_codex":0.000023397917,"about_ca_topic_score_gemma":0.0000017888462,"teacher_disagreement_score":0.03289151,"about_ca_system_score_codex":0.000101832586,"about_ca_system_score_gemma":0.000036659585,"threshold_uncertainty_score":0.9999599},"labels":[],"label_agreement":null},{"id":"W2126437964","doi":"10.1124/mol.61.3.649","title":"Synthesis and Evaluation of a New Class of Nifedipine Analogs with T-Type Calcium Channel Blocking Activity","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":84,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Heart and Stroke Foundation of Canada","keywords":"Chemistry; Calcium channel; Nifedipine; Stereochemistry; Voltage-dependent calcium channel; L-type calcium channel; T-type calcium channel; Pyridine; Substituent; Selectivity; Calcium; Alkoxy group; Biochemistry; Medicinal chemistry; Organic chemistry","score_opus":0.13581043867355266,"score_gpt":0.38823591382728706,"score_spread":0.25242547515373437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126437964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99768525,0.0001575461,0.000113046284,0.0008841269,0.00024460812,0.00047256728,0.000006011585,0.000021967642,0.00041484405],"genre_scores_gemma":[0.99895424,0.00016322995,0.000014520809,0.0006926579,0.000038979066,0.000029225594,1.1730278e-7,0.000019622319,0.00008738884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99740624,0.00083559775,0.00021104442,0.0005234399,0.0006447248,0.0003789557],"domain_scores_gemma":[0.9989669,0.0003369318,0.00018453659,0.00018038579,0.00017333192,0.0001579444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046666988,0.00016575996,0.0003058606,0.00028007422,0.00009308126,0.000009423775,0.0002861587,0.000074149386,0.00034381112],"category_scores_gemma":[0.00040972867,0.00014723327,0.0000446484,0.0008054427,0.0005469118,0.00012740357,0.00013812265,0.00025659142,0.000006683839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021085532,0.00023238885,0.00016060029,0.000029760675,0.000019742567,0.00011322455,0.00009434113,0.00049990445,0.9945815,0.000016081947,0.00040061778,0.00364097],"study_design_scores_gemma":[0.0012669544,0.00056370586,0.0004983752,0.000009486042,0.00018940045,0.00008816404,0.000005796833,0.040491495,0.9566233,0.000029171793,0.00011988272,0.0001142631],"about_ca_topic_score_codex":0.000019908877,"about_ca_topic_score_gemma":0.0000015348658,"teacher_disagreement_score":0.03999159,"about_ca_system_score_codex":0.000027394737,"about_ca_system_score_gemma":0.00013057876,"threshold_uncertainty_score":0.60039985},"labels":[],"label_agreement":null},{"id":"W2127164959","doi":"10.1124/mol.104.009506","title":"A Single Residue in the S6 Transmembrane Domain Governs the Differential Flecainide Sensitivity of Voltage-Gated Potassium Channels","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Flecainide; Xenopus; Chemistry; Biophysics; Transmembrane domain; Potassium channel; Biochemistry; Biology; Amino acid; Internal medicine; Medicine","score_opus":0.009253253975200148,"score_gpt":0.2652525337736582,"score_spread":0.25599927979845805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127164959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9776982,0.00026966122,0.0020608816,0.018422926,0.00025772201,0.0006564018,0.000018420658,0.000027455171,0.00058830396],"genre_scores_gemma":[0.992537,0.000035791887,0.00004693899,0.0067157815,0.00048638732,0.00003612465,0.000028899616,0.000022875347,0.00009018645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975834,0.0011560187,0.00030532628,0.00029250054,0.00022060543,0.00044215398],"domain_scores_gemma":[0.9991662,0.00034856697,0.000099086945,0.00027487703,0.000052359497,0.000058923037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058593665,0.00020418929,0.00044895767,0.0000817346,0.00008732838,0.0000067170963,0.00013032899,0.00016340901,0.0001410457],"category_scores_gemma":[0.00004717813,0.00013001669,0.00024743294,0.00029119282,0.00030186886,0.000040250092,0.00004098675,0.0005879594,0.000013693706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00097479025,0.0003965859,0.000033364147,0.000030317866,0.00019526127,0.0016029205,0.00070743624,0.00068963144,0.99267673,0.00031334138,0.0010558846,0.0013237533],"study_design_scores_gemma":[0.0037207443,0.00044170595,0.0039066384,0.000019968556,0.0003432057,0.00081359403,0.00009717016,0.0013377611,0.98447895,0.0001640356,0.004513845,0.00016238066],"about_ca_topic_score_codex":0.000059371116,"about_ca_topic_score_gemma":0.00005944866,"teacher_disagreement_score":0.014838787,"about_ca_system_score_codex":0.00006530716,"about_ca_system_score_gemma":0.000080162215,"threshold_uncertainty_score":0.5301927},"labels":[],"label_agreement":null},{"id":"W2127513830","doi":"10.1124/mol.60.1.42","title":"Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Secretoneurin Release and Secretogranin II Gene Transcription in Bovine Adrenochromaffin Cells through Multiple Signaling Pathways and Increased Binding of Pre-Existing Activator Protein-1-Like Transcription Factors","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Armand Frappier Museum","funders":"","keywords":"Pituitary adenylate cyclase-activating peptide; Protein kinase C; Activator (genetics); Protein kinase A; Internal medicine; Endocrinology; Adenylate kinase; Biology; Forskolin; Signal transduction; Chemistry; Molecular biology; Neuropeptide; Kinase; Cell biology; Receptor; Vasoactive intestinal peptide; Biochemistry; Stimulation","score_opus":0.03387376099928584,"score_gpt":0.26354234912157243,"score_spread":0.22966858812228658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127513830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979973,0.00018492999,0.00041195133,0.000032989534,0.00012241327,0.0010129075,0.000100516285,0.000108692075,0.000028342363],"genre_scores_gemma":[0.9985326,0.000100822544,0.00080669357,0.0003221601,0.000055206077,0.00004994776,0.000038674523,0.00008062395,0.000013275522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99696064,0.00062679645,0.00064011395,0.0009170433,0.00022158945,0.00063384126],"domain_scores_gemma":[0.99901545,0.00029354836,0.00031565333,0.00015883661,0.000038336093,0.00017816029],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017248186,0.0004428312,0.0005522337,0.00024998802,0.00034367337,0.000031478357,0.00019229192,0.00017072757,0.000059171674],"category_scores_gemma":[0.00012738981,0.00045947987,0.00010959619,0.00044404558,0.00027283048,0.0004312208,0.000118022435,0.0005246914,0.0000011527137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001385098,0.00024880338,0.0007193824,0.0001508494,0.000025563239,0.00038572957,0.0012154081,0.0011665286,0.99419,0.000029724259,0.0000020853731,0.0004808393],"study_design_scores_gemma":[0.0027056793,0.000987343,0.0026917032,0.000114751936,0.000051834057,0.000058725924,0.00013080369,0.0071818912,0.98552734,0.00009077452,0.00006401245,0.00039513267],"about_ca_topic_score_codex":0.0005405711,"about_ca_topic_score_gemma":0.000012468197,"teacher_disagreement_score":0.00866264,"about_ca_system_score_codex":0.000056023924,"about_ca_system_score_gemma":0.00004783427,"threshold_uncertainty_score":0.9997857},"labels":[],"label_agreement":null},{"id":"W2127626106","doi":"10.1124/mol.114.091777","title":"A Plasma Concentration of α-Ketoglutarate Influences the Kinetic Interaction of Ligands with Organic Anion Transporter 1","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Probenecid; Extracellular; Organic anion transporter 1; Chinese hamster ovary cell; Transporter; Stereochemistry; Pharmacology; Biochemistry; Receptor; Biology","score_opus":0.006174104232770362,"score_gpt":0.2518105995522456,"score_spread":0.24563649531947523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127626106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99070394,0.00006374133,0.0077810064,0.0006420711,0.00018298671,0.00029573386,0.0000022967795,0.000015079755,0.00031315163],"genre_scores_gemma":[0.99930227,0.000039169237,0.00016297055,0.00037423638,0.00003534649,0.000013735455,0.00001685736,0.000012999058,0.000042445554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992573,0.000045328554,0.00026175694,0.00014279499,0.00016085069,0.00013192628],"domain_scores_gemma":[0.9995612,0.000025929714,0.00015287027,0.000109377535,0.000108460175,0.000042162785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013276581,0.000104123115,0.00023645355,0.0000429125,0.000024311197,0.0000023909486,0.000072807255,0.000059117327,0.00018114442],"category_scores_gemma":[0.000003717644,0.000057865156,0.00005561899,0.00016311176,0.00013685558,0.00003693507,0.0000034406671,0.00012212168,0.0000024455237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007783736,0.00009416446,0.0020747767,0.00009960587,0.00011241915,0.00002027885,0.00044317933,0.0002723704,0.99521244,0.00018628697,0.000015074675,0.0006910228],"study_design_scores_gemma":[0.002095449,0.0007189499,0.0082649365,0.000064769614,0.00042288654,0.000031169584,0.000080740356,0.0012595309,0.9862508,0.00004028431,0.00070467766,0.00006579182],"about_ca_topic_score_codex":0.000010060657,"about_ca_topic_score_gemma":0.000013167744,"teacher_disagreement_score":0.008961633,"about_ca_system_score_codex":0.000012185851,"about_ca_system_score_gemma":0.000052753636,"threshold_uncertainty_score":0.23596726},"labels":[],"label_agreement":null},{"id":"W2127668220","doi":"10.1124/mol.64.2.346","title":"Oltipraz Is a Bifunctional Inducer Activating Both Phase I and Phase II Drug-Metabolizing Enzymes via the Xenobiotic Responsive Element","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Bifunctional; Inducer; Xenobiotic; Enzyme; Chemistry; Phase (matter); Drug; Biochemistry; Pharmacology; Biology; Organic chemistry; Gene","score_opus":0.012131821941778111,"score_gpt":0.3059870822666118,"score_spread":0.2938552603248337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127668220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98869,0.004491523,0.004446522,0.0009297665,0.00038375912,0.0005290076,0.00006452463,0.000015087605,0.00044979234],"genre_scores_gemma":[0.9928977,0.00020823561,0.00085337023,0.005357486,0.00022257109,0.00010213919,0.00008570808,0.000043481537,0.00022934236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99795294,0.0004105746,0.0003358742,0.00064489595,0.00016364286,0.00049205165],"domain_scores_gemma":[0.9991636,0.00006078597,0.00019460959,0.0002978956,0.00012983306,0.0001532506],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003697298,0.00032338608,0.0002660616,0.00008542119,0.00040173318,0.000030384494,0.00021996493,0.00014720824,0.0002836178],"category_scores_gemma":[0.00012324852,0.00028152033,0.00012717259,0.00014437728,0.00026533825,0.00000984807,0.00022931071,0.000288463,0.0000066225734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003853698,0.00048608953,0.000053543346,0.00001363992,0.00033546885,0.00001615391,0.00033027687,0.000024502837,0.99046916,0.00023094646,0.004775523,0.0028793241],"study_design_scores_gemma":[0.005254188,0.00038708237,0.00004852728,0.0000053195868,0.00011032073,0.00004393247,0.00022084184,0.00008712211,0.8722509,0.00020790462,0.1211091,0.00027476164],"about_ca_topic_score_codex":0.000008895207,"about_ca_topic_score_gemma":0.0000020825835,"teacher_disagreement_score":0.11821826,"about_ca_system_score_codex":0.000034473782,"about_ca_system_score_gemma":0.0001478835,"threshold_uncertainty_score":0.9999637},"labels":[],"label_agreement":null},{"id":"W2128445664","doi":"10.1124/mol.104.005553","title":"Ertiprotafib Improves Glycemic Control and Lowers Lipids via Multiple Mechanisms","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Peroxisome proliferator-activated receptor; Triglyceride; Insulin; Endocrinology; Glucose uptake; Adipocyte; Internal medicine; Chemistry; In vivo; Mechanism of action; Receptor; Peroxisome; Glycemic; Pharmacology; In vitro; Biology; Biochemistry; Adipose tissue; Medicine; Cholesterol","score_opus":0.003302349571449976,"score_gpt":0.2272876114022519,"score_spread":0.22398526183080192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128445664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92893463,0.00091432314,0.067888394,0.0006995104,0.0006963486,0.0007006741,0.000018574878,0.000060895756,0.000086653155],"genre_scores_gemma":[0.9928747,0.00010700025,0.0017469412,0.004695706,0.00020835108,0.00020614972,0.00004887424,0.00007023884,0.00004204968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821925,0.00012576942,0.00027770104,0.00067036616,0.00014685841,0.00056003587],"domain_scores_gemma":[0.99926895,0.000014584241,0.00010847539,0.00026941916,0.00008872534,0.00024984882],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013712294,0.0003420655,0.00029041758,0.00009432814,0.00012298148,0.000024988463,0.00025568163,0.0003605917,0.00003663966],"category_scores_gemma":[0.00005476581,0.00034690145,0.00012131745,0.000119480865,0.00020292096,0.0000097571365,0.00016047685,0.00025907418,0.000027138198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009864279,0.00012943814,0.00011111896,0.00001966359,0.00026433927,0.000035956742,0.000029081539,0.00025829367,0.9966586,0.000060885,0.00021359458,0.0012325711],"study_design_scores_gemma":[0.007853489,0.0009461172,0.00003835886,0.0000054495263,0.000081613915,0.00009534317,0.000017573795,0.00023813824,0.9848049,0.00044147318,0.005097128,0.00038040563],"about_ca_topic_score_codex":0.00002814,"about_ca_topic_score_gemma":0.0000046398177,"teacher_disagreement_score":0.06614146,"about_ca_system_score_codex":0.000058667378,"about_ca_system_score_gemma":0.00012254245,"threshold_uncertainty_score":0.9998983},"labels":[],"label_agreement":null},{"id":"W2128670872","doi":"10.1124/mol.110.063859","title":"The Angiotensin II Type 1 Receptor Induces Membrane Blebbing by Coupling to Rho A, Rho Kinase, and Myosin Light Chain Kinase","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"RHOA; Myosin light-chain kinase; Angiotensin II; Cell biology; Rho-associated protein kinase; Kinase; Biology; Myosin; Chemistry; Signal transduction; Receptor; Biochemistry","score_opus":0.005582679800888398,"score_gpt":0.24745049505536265,"score_spread":0.24186781525447426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128670872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99102753,0.0026273825,0.0005357969,0.0035128477,0.0016952064,0.00042252496,0.00001487868,0.00002435897,0.00013945518],"genre_scores_gemma":[0.99479914,0.0003606558,0.0014724705,0.0021289007,0.00045341218,0.00004608679,0.00007017098,0.000063344065,0.0006058033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982438,0.00010339926,0.00029793702,0.00061927934,0.0001737687,0.0005618193],"domain_scores_gemma":[0.9990996,0.00003691712,0.00011124121,0.00031604894,0.00016746573,0.00026871797],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057101273,0.00030273266,0.00025050668,0.0000697524,0.0005325769,0.00007300302,0.00033638437,0.00032854135,0.00024644713],"category_scores_gemma":[0.00009953836,0.0002567971,0.00009046438,0.00020432622,0.00010882738,0.0000071481068,0.00032402793,0.00037680328,0.000022213118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014115078,0.000053922977,0.000010515509,0.0000066244897,0.00010522557,0.000017826516,0.00009621209,0.000086722146,0.98483115,0.00009405497,0.0120084835,0.0025480865],"study_design_scores_gemma":[0.00047223567,0.00031611952,0.0000038658027,0.000007129279,0.000042269647,0.000014797618,0.000045527428,0.00027277874,0.769448,0.000018314491,0.22910501,0.0002539745],"about_ca_topic_score_codex":0.000027937904,"about_ca_topic_score_gemma":0.00001979003,"teacher_disagreement_score":0.21709652,"about_ca_system_score_codex":0.000015824913,"about_ca_system_score_gemma":0.00007912107,"threshold_uncertainty_score":0.99998844},"labels":[],"label_agreement":null},{"id":"W2129173144","doi":"10.1124/mol.107.039388","title":"The Molecular Basis of High-Affinity Binding of the Antiarrhythmic Compound Vernakalant (RSD1235) to Kv1.5 Channels","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Flecainide; Chemistry; Allosteric regulation; Biophysics; Pharmacology; IC50; Stereochemistry; Biochemistry; Receptor; Biology; Atrial fibrillation; In vitro; Medicine; Internal medicine","score_opus":0.007581612810856052,"score_gpt":0.279740071687826,"score_spread":0.27215845887696993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129173144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99275863,0.0006814663,0.0012293112,0.0028136617,0.0012812942,0.0007619542,0.000019371337,0.00002402,0.00043026943],"genre_scores_gemma":[0.9974787,0.00007979968,0.00018062387,0.0019123515,0.00019565463,0.000023259341,0.000008802492,0.000031374362,0.000089435554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808043,0.00029162812,0.00046576274,0.0003103445,0.0003033736,0.0005484553],"domain_scores_gemma":[0.99871296,0.00028092385,0.00023694155,0.00046004137,0.00017309246,0.00013607269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006858078,0.00021619994,0.0005297474,0.00013983384,0.0001782367,0.0000053274316,0.0002777694,0.00015246027,0.000052281972],"category_scores_gemma":[0.00011945598,0.00014475407,0.00034673561,0.000535578,0.00035678194,0.00002055719,0.00022046815,0.0004113119,0.00002124338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007569089,0.00009226018,0.00025336698,0.000041543055,0.00045009665,0.0008341222,0.000095781084,0.00069372606,0.99340117,0.0015787429,0.000754678,0.0010475861],"study_design_scores_gemma":[0.001373694,0.00035178414,0.0052967034,0.000035808767,0.000326189,0.00039753318,0.000030003204,0.000054414053,0.98949164,0.00020038796,0.002308319,0.00013349847],"about_ca_topic_score_codex":0.00005614976,"about_ca_topic_score_gemma":0.0000051002335,"teacher_disagreement_score":0.005043336,"about_ca_system_score_codex":0.000072187984,"about_ca_system_score_gemma":0.00013736504,"threshold_uncertainty_score":0.59028995},"labels":[],"label_agreement":null},{"id":"W2129515100","doi":"10.1124/mol.106.024273","title":"A Single Decoy Oligodeoxynucleotides Targeting Multiple Oncoproteins Produces Strong Anticancer Effects","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Decoy; Targeted therapy; Transcription factor; In vivo; Cancer research; Biology; E2F; Cancer; Pharmacology; Computational biology; Gene; Genetics; Receptor","score_opus":0.006565180214880819,"score_gpt":0.25178305010475777,"score_spread":0.24521786988987695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129515100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99130034,0.0024815237,0.003805019,0.00021696677,0.0005689386,0.0004938074,0.000011069653,0.00004632276,0.0010760324],"genre_scores_gemma":[0.99612695,0.000068357615,0.001665738,0.00084677414,0.00071074977,0.00012297247,0.00011120511,0.00005011065,0.0002971336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982169,0.00016330853,0.0002960338,0.0006253325,0.00015090752,0.0005474977],"domain_scores_gemma":[0.9993824,0.000026756454,0.00012425949,0.00025385802,0.00012529643,0.000087473396],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015504497,0.00027513911,0.00024513624,0.00007495192,0.00011938888,0.000036648973,0.00028895398,0.00016379241,0.00006527135],"category_scores_gemma":[0.00006107591,0.0002789712,0.00014837873,0.00011787538,0.00013317328,0.0000095916985,0.00013070933,0.00014941342,0.000048334532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107058164,0.00023810941,0.0019984327,0.000040656596,0.00010791695,0.0000824011,0.000019527994,0.0007828789,0.98695236,0.000022961769,0.008069932,0.0015777693],"study_design_scores_gemma":[0.00096738554,0.0004891108,0.0008281368,0.000014618142,0.00006467349,0.000015501782,0.000017347264,0.00033427548,0.97929037,0.00005378227,0.017610297,0.00031450271],"about_ca_topic_score_codex":0.00013245833,"about_ca_topic_score_gemma":0.00006547517,"teacher_disagreement_score":0.009540363,"about_ca_system_score_codex":0.000037054207,"about_ca_system_score_gemma":0.00006575734,"threshold_uncertainty_score":0.99996626},"labels":[],"label_agreement":null},{"id":"W2129820672","doi":"10.1124/mol.59.5.1171","title":"Modulation of Multidrug Resistance Protein 1 (MRP1/ABCC1) Transport and ATPase Activities by Interaction with Dietary Flavonoids","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":232,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Naringenin; Apigenin; ABCC1; Kaempferol; Glutathione; Chemistry; Biochemistry; Myricetin; Quercetin; Pharmacology; Flavonoid; ATP-binding cassette transporter; Biology; Antioxidant; Transporter; Enzyme","score_opus":0.007217654871207832,"score_gpt":0.2575546792955961,"score_spread":0.25033702442438827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129820672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884411,0.0004977124,0.008710033,0.00066734606,0.00009518548,0.00071122637,0.000018242057,0.000053464602,0.0008056725],"genre_scores_gemma":[0.9960945,0.00013951786,0.001667946,0.00022772266,0.000036853566,0.000085987536,0.00010190177,0.000033273078,0.0016122708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989746,0.000052353964,0.00025250448,0.00030197224,0.00019753886,0.00022101868],"domain_scores_gemma":[0.9995804,0.000014128145,0.0001140125,0.00013492836,0.00005334018,0.00010319675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010263732,0.0001855695,0.00032446074,0.00010331669,0.000054893007,0.000003361444,0.00005029635,0.000094680385,0.00008715421],"category_scores_gemma":[0.0000021140986,0.00016019617,0.00006385107,0.00014550428,0.00014147679,0.00012420962,0.0000060629195,0.00019960105,0.000001059556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034973095,0.0002637513,0.0017838842,0.00022972604,0.00014997314,0.00041824466,0.00027689908,0.000069762245,0.9920771,0.0000364818,0.00013515413,0.0010616885],"study_design_scores_gemma":[0.0034476265,0.0003746521,0.0046995,0.00014143006,0.00031137388,0.00004039071,0.00017046325,0.00063635304,0.985979,0.000054497665,0.0039384007,0.00020629389],"about_ca_topic_score_codex":0.00004094766,"about_ca_topic_score_gemma":0.00006453849,"teacher_disagreement_score":0.007653409,"about_ca_system_score_codex":0.00004097711,"about_ca_system_score_gemma":0.000045406636,"threshold_uncertainty_score":0.653261},"labels":[],"label_agreement":null},{"id":"W2130141176","doi":"10.1124/mol.113.087551","title":"Muscarinic Receptors as Model Targets and Antitargets for Structure-Based Ligand Discovery","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Division of Chemistry; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Bayerisch-Kalifornischen Hochschulzentrum; Emory University; National Institutes of Health; National Science Foundation","keywords":"Receptor; G protein-coupled receptor; Muscarinic acetylcholine receptor; Docking (animal); Agonist; Allosteric regulation; Chemistry; Stereochemistry; Muscarinic acetylcholine receptor M2; Muscarinic acetylcholine receptor M3; Drug discovery; Biochemistry","score_opus":0.0064318981385366,"score_gpt":0.25673492907663936,"score_spread":0.25030303093810274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130141176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9172246,0.0013351901,0.07968146,0.00033647052,0.00055910955,0.0007150626,0.000034272853,0.000018926943,0.0000948965],"genre_scores_gemma":[0.9890988,0.00009246696,0.0072695087,0.002597468,0.00016594569,0.00016242715,0.0001929136,0.0000560207,0.00036448112],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986178,0.00006593407,0.00023283761,0.0005518517,0.00010705281,0.00042446793],"domain_scores_gemma":[0.99943584,0.000019713345,0.00009153919,0.00019028214,0.000111167086,0.00015145213],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011296723,0.00026054063,0.00024047376,0.00006839648,0.00012255709,0.000059184917,0.00018555633,0.00024186951,0.00022911793],"category_scores_gemma":[0.000036782163,0.00024941706,0.00013232288,0.000054431526,0.00008711369,0.000015126348,0.00010315872,0.0001150282,0.0000075382236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009040829,0.000040377727,0.000050992523,0.000031937405,0.00010139248,0.000004608273,0.000020191403,0.0036899499,0.991835,0.00023266967,0.003180785,0.00072166364],"study_design_scores_gemma":[0.0013421911,0.00038101722,0.00001841854,0.000004945589,0.00006253523,0.000009247244,0.000015852389,0.018093523,0.97289175,0.0019373606,0.004941067,0.0003020974],"about_ca_topic_score_codex":0.000021106296,"about_ca_topic_score_gemma":0.0000032062976,"teacher_disagreement_score":0.072411954,"about_ca_system_score_codex":0.00001480467,"about_ca_system_score_gemma":0.000107547654,"threshold_uncertainty_score":0.9999958},"labels":[],"label_agreement":null},{"id":"W2130236597","doi":"10.1124/mol.65.6.1375","title":"Mutations of Charged Amino Acids in or near the Transmembrane Helices of the Second Membrane Spanning Domain Differentially Affect the Substrate Specificity and Transport Activity of the Multidrug Resistance Protein MRP1 (ABCC1)","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Mutant; Transmembrane domain; Membrane transport; Crystallography; Stereochemistry; Membrane transport protein; Substrate (aquarium); Amino acid; Biophysics; Membrane; Membrane protein; Biochemistry; Biology; Gene","score_opus":0.011239569975350073,"score_gpt":0.2589542311206902,"score_spread":0.24771466114534013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130236597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931854,0.00033247558,0.00080813677,0.0028258965,0.00015813403,0.002399974,0.00008750748,0.000013152362,0.00018930096],"genre_scores_gemma":[0.99914086,0.00004005611,0.00023583283,0.00013385985,0.000024234945,0.00009916935,0.0000057569687,0.000028304441,0.00029195097],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803907,0.00041372443,0.00052372494,0.00031213593,0.00039800862,0.00031335605],"domain_scores_gemma":[0.9990039,0.000112824855,0.0003408816,0.00040712152,0.000080794256,0.000054490465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006216071,0.00025561816,0.00055711856,0.000058557813,0.00022715332,0.000007984588,0.00041920427,0.00012682281,0.0001325686],"category_scores_gemma":[0.00001230806,0.0001174956,0.00026384147,0.00045746664,0.0011550735,0.000053840773,0.00002211921,0.000512835,3.0673436e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018068793,0.00036473616,0.0011174738,0.0007672464,0.00018918834,0.000052809333,0.004223434,0.00032761536,0.9906865,0.0003898332,0.0000010306584,0.00007325549],"study_design_scores_gemma":[0.0039051902,0.00009225898,0.12730788,0.0002126785,0.00027981182,0.000010865226,0.00030343395,0.000046175686,0.86744046,0.00019151688,0.00010540004,0.000104365456],"about_ca_topic_score_codex":0.00010277916,"about_ca_topic_score_gemma":0.003308727,"teacher_disagreement_score":0.1261904,"about_ca_system_score_codex":0.000034476863,"about_ca_system_score_gemma":0.00029268017,"threshold_uncertainty_score":0.47913316},"labels":[],"label_agreement":null},{"id":"W2130336163","doi":"10.1124/mol.64.2.298","title":"Isoprostane-Mediated Secretion from Human Airway Epithelial Cells","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Secretion; Airway; Isoprostane; Chemistry; Cell biology; Biology; Biochemistry; Medicine; Oxidative stress","score_opus":0.008613256456135051,"score_gpt":0.2823191511299053,"score_spread":0.27370589467377027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130336163","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936594,0.00078298454,0.00089386955,0.0002730268,0.00061191805,0.0004363515,0.00007490525,0.00010262599,0.0031649573],"genre_scores_gemma":[0.9936846,0.000023141683,0.00014046274,0.0052135168,0.00021764183,0.000038560058,0.0001696391,0.00003830186,0.00047415003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986593,0.0002484132,0.0002445857,0.00033732806,0.00019461488,0.0003157158],"domain_scores_gemma":[0.9993549,0.000037123627,0.00007705802,0.00018332832,0.00007567437,0.00027189538],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009782264,0.00018509894,0.0002696729,0.00009256862,0.000097548516,0.000008269691,0.00007476361,0.00015851507,0.0041890177],"category_scores_gemma":[0.000030930692,0.00016911929,0.0001335299,0.00013744812,0.00012848852,0.000030956136,0.000023520217,0.0002221969,0.0004309761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012294727,0.00025080788,0.00066688034,0.000018869358,0.000084959196,0.0010677095,0.000053342566,0.000013942444,0.9931512,0.00010507545,0.004044292,0.00041996624],"study_design_scores_gemma":[0.0030614375,0.00032166508,0.0008941,0.000008487887,0.00023681633,0.00001627788,0.000035176792,0.00005823466,0.8611844,0.00012356877,0.1338942,0.00016563202],"about_ca_topic_score_codex":0.000016785418,"about_ca_topic_score_gemma":0.0000012993507,"teacher_disagreement_score":0.13196681,"about_ca_system_score_codex":0.00005576201,"about_ca_system_score_gemma":0.00012808695,"threshold_uncertainty_score":0.99672127},"labels":[],"label_agreement":null},{"id":"W2130381085","doi":"10.1124/mol.104.005884","title":"Residue 33 of Human Equilibrative Nucleoside Transporter 2 Is a Functionally Important Component of Both the Dipyridamole and Nucleoside Binding Sites","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research","funders":"","keywords":"Nucleoside; Chemistry; Dipyridamole; Adenosine; Nucleoside transporter; Stereochemistry; Uridine; Purine; Residue (chemistry); Footprinting; Biochemistry; Transporter; Enzyme; DNA; RNA; Gene","score_opus":0.011266606038308815,"score_gpt":0.27422502903559454,"score_spread":0.2629584229972857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130381085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99439436,0.0034097852,0.0005665484,0.0009161922,0.000049054826,0.00023199576,0.00006385077,0.000008655746,0.0003595301],"genre_scores_gemma":[0.99767005,0.00012782024,0.00042415786,0.0013811089,0.00015217632,0.000018037494,0.000083522995,0.00002913602,0.00011400433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871504,0.000107185086,0.0004641048,0.00032089368,0.00015562208,0.00023712184],"domain_scores_gemma":[0.99937886,0.000030185947,0.00024848312,0.00020010867,0.000071954055,0.0000704124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020585294,0.00019203249,0.00025755828,0.00006811222,0.00009540375,0.000008029503,0.0001986361,0.00011560303,0.00027493553],"category_scores_gemma":[0.000007610236,0.00015721461,0.00013216981,0.00009465816,0.00025289637,0.00000849312,0.000101989324,0.0001288553,0.00000166311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019777281,0.000112317575,0.004580489,0.000029905323,0.00026903764,0.000019047537,0.00028688746,0.00017959742,0.9856257,0.0002984125,0.008342794,0.000058081594],"study_design_scores_gemma":[0.0009877788,0.00037055943,0.0045595593,0.000014237363,0.00015680102,0.000027792084,0.00007782957,0.00022995642,0.98895943,0.000093174094,0.004354488,0.00016838544],"about_ca_topic_score_codex":0.00003573566,"about_ca_topic_score_gemma":0.0000117779955,"teacher_disagreement_score":0.0039883065,"about_ca_system_score_codex":0.000008844883,"about_ca_system_score_gemma":0.000051684972,"threshold_uncertainty_score":0.64110255},"labels":[],"label_agreement":null},{"id":"W2130849131","doi":"10.1124/mol.112.079616","title":"Cysteine Residues in the Transmembrane (TM) 9 to TM11 Region of the Human Equilibrative Nucleoside Transporter Subtype 1 Play an Important Role in Inhibitor Binding and Translocation Function","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Nucleoside; Cysteine; Transporter; Transmembrane protein; Function (biology); Chromosomal translocation; Chemistry; Biochemistry; Stereochemistry; Biology; Cell biology; Gene; Receptor","score_opus":0.012770802172992137,"score_gpt":0.27076939075079626,"score_spread":0.2579985885778041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130849131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99596006,0.002113419,0.00074956234,0.0005507784,0.00009363849,0.0004510096,0.0000053555013,0.000005056245,0.00007111367],"genre_scores_gemma":[0.9989787,0.000049425747,0.000038920083,0.00066023803,0.00013749437,0.000049545593,0.000053137355,0.000019244104,0.000013328487],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987744,0.00030638088,0.00033090552,0.0002349118,0.00010759953,0.0002457774],"domain_scores_gemma":[0.9996353,0.000014007728,0.00010561814,0.00016627739,0.000024336323,0.00005450248],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038692527,0.0001437784,0.00015751754,0.00009094425,0.000055703622,0.0000067724454,0.00016183183,0.00012815243,0.0000131158895],"category_scores_gemma":[0.0000072686016,0.00010411698,0.00005150445,0.0002190074,0.000065840715,0.000019389074,0.000017595226,0.00014598854,3.801769e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025079158,0.00012872981,0.012202075,0.000018608715,0.000023984765,0.000013780635,0.0022882244,0.00021811549,0.9844592,0.00012559613,0.00013159997,0.00013926343],"study_design_scores_gemma":[0.0011952708,0.000466882,0.022411283,0.00002556579,0.000059152873,0.000035784455,0.00047534215,0.000044713513,0.97431237,0.000062137195,0.00076313404,0.00014835723],"about_ca_topic_score_codex":0.000082690414,"about_ca_topic_score_gemma":0.00014011959,"teacher_disagreement_score":0.010209208,"about_ca_system_score_codex":0.000010890855,"about_ca_system_score_gemma":0.000029010702,"threshold_uncertainty_score":0.42457673},"labels":[],"label_agreement":null},{"id":"W2131441643","doi":"10.1124/mol.107.039354","title":"Dexamethasone-Mediated Up-Regulation of Human CYP2A6 Involves the Glucocorticoid Receptor and Increased Binding of Hepatic Nuclear Factor 4α to the Proximal Promoter","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Chromatin immunoprecipitation; Hepatocyte nuclear factor 4; Transactivation; Glucocorticoid receptor; Molecular biology; Biology; Electrophoretic mobility shift assay; Promoter; Transcription factor; Chemistry; Endocrinology; Nuclear receptor; Gene expression; Glucocorticoid; Gene; Biochemistry","score_opus":0.05278774633892928,"score_gpt":0.3865000972303615,"score_spread":0.3337123508914322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131441643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943569,0.0008427967,0.00019390965,0.0010383065,0.0011510053,0.0020303808,0.00011351716,0.000042488977,0.00023072354],"genre_scores_gemma":[0.99636835,0.000115063114,0.00024132761,0.0028601466,0.00018404298,0.000067649155,0.000033904373,0.000058549205,0.00007093866],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966567,0.001141459,0.0008167657,0.00043330799,0.00032794365,0.0006238183],"domain_scores_gemma":[0.99800235,0.0006974107,0.00047981332,0.0003122303,0.00022680423,0.00028140066],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0018846836,0.00033821538,0.00050827244,0.00026141218,0.00028175683,0.00001724844,0.00056121143,0.00028731208,0.0016705061],"category_scores_gemma":[0.00017436137,0.000241598,0.00014775102,0.0005243024,0.00051979255,0.0000694167,0.00030185096,0.0006717215,0.00006833006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005119507,0.00026795964,0.004692264,0.00009985581,0.00040642347,0.0000093741055,0.002591093,0.00010019342,0.98488027,0.00033394204,0.0006051179,0.0055015828],"study_design_scores_gemma":[0.0026134949,0.000310663,0.014345286,0.00001440199,0.00046398002,0.000010329898,0.00019066558,0.0020741688,0.95602375,0.00007378159,0.02361867,0.0002608133],"about_ca_topic_score_codex":0.00005584959,"about_ca_topic_score_gemma":0.000009890982,"teacher_disagreement_score":0.0288565,"about_ca_system_score_codex":0.00005243796,"about_ca_system_score_gemma":0.00009281824,"threshold_uncertainty_score":0.9992421},"labels":[],"label_agreement":null},{"id":"W2132127856","doi":"10.1124/mol.105.019844","title":"Molecular Determinants in the Second Intracellular Loop of the 5-Hydroxytryptamine-1A Receptor for G-Protein Coupling","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Institute of Mental Health","keywords":"G protein-coupled receptor; Biophysics; G protein; Chemistry; Receptor; Allosteric regulation; Signal transduction; Adenylyl cyclase; Agonist; Protein subunit; Stereochemistry; Cell biology; Biology; Biochemistry","score_opus":0.006943933593932165,"score_gpt":0.24907968578154502,"score_spread":0.24213575218761285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132127856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871707,0.0013540481,0.009509147,0.00027330517,0.0003878484,0.0011577219,0.000033592285,0.000007537592,0.000106129046],"genre_scores_gemma":[0.9978463,0.000011460207,0.00061727944,0.00068518036,0.00018217128,0.0002567597,0.00003908932,0.000047819958,0.00031393796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982146,0.00020073705,0.00047921084,0.00044695585,0.00020106137,0.00045741157],"domain_scores_gemma":[0.99918836,0.00002880168,0.0002320551,0.00040861525,0.000101215,0.000040927676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058637775,0.00025941356,0.00027574855,0.000063692496,0.00010774612,0.000020172192,0.00066860113,0.00025658074,0.00016855152],"category_scores_gemma":[0.000040578303,0.00019087004,0.00026340486,0.0002006204,0.00013842752,0.00000514424,0.00013576885,0.00021117034,0.0000031659195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000917289,0.00011889862,0.00015151565,0.000058569596,0.000039206257,0.000019585414,0.000023501923,0.0023755133,0.9959001,0.00043428072,0.0005964858,0.00019062463],"study_design_scores_gemma":[0.0012150697,0.00021466755,0.000036764493,0.000019100005,0.000044121378,0.000014417722,0.00004685007,0.0024754247,0.98359877,0.00038790633,0.011725814,0.00022107351],"about_ca_topic_score_codex":0.000026770585,"about_ca_topic_score_gemma":0.000031206175,"teacher_disagreement_score":0.012301299,"about_ca_system_score_codex":0.00002257309,"about_ca_system_score_gemma":0.00008456166,"threshold_uncertainty_score":0.77834547},"labels":[],"label_agreement":null},{"id":"W2132592929","doi":"10.1124/mol.104.002303","title":"Low-Affinity Neurotensin Receptor (NTS2) Signaling: Internalization-Dependent Activation of Extracellular Signal-Regulated Kinases 1/2","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Internalization; Chinese hamster ovary cell; Neurotensin receptor; Receptor; G protein-coupled receptor; Agonist; Neurotensin; Enzyme-linked receptor; Inverse agonist; Biology; Chemistry; Molecular biology; Cell biology; Biochemistry; Neuropeptide","score_opus":0.02345634391899836,"score_gpt":0.2728813914946625,"score_spread":0.24942504757566414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132592929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934757,0.000035153862,0.0051385625,0.00027640854,0.0003986759,0.0004139335,0.000014022306,0.00010021838,0.00014732634],"genre_scores_gemma":[0.9970604,0.000028776261,0.00013300535,0.0025121407,0.000097947785,0.000018497687,0.000013464678,0.00005219229,0.000083582716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778455,0.00043461105,0.0004904195,0.0006232336,0.00028191094,0.00038527133],"domain_scores_gemma":[0.99903774,0.00014490575,0.00034193543,0.00021076475,0.00014353749,0.000121135294],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010794496,0.00026428993,0.00032990862,0.00017018495,0.00011077613,0.00002305715,0.00038886597,0.00011420905,0.0006571593],"category_scores_gemma":[0.00017141576,0.00026771278,0.00013933191,0.00039129818,0.00023617098,0.00015065316,0.00015970644,0.00029544148,0.000089378445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002947863,0.0004788504,0.000011633445,0.00003245192,0.000020827041,0.000216006,0.0000565099,0.024736714,0.9721418,0.0015278606,0.00010699696,0.00037555053],"study_design_scores_gemma":[0.0013688211,0.00049631344,0.00006404215,0.00003433874,0.00003639971,0.00002820033,0.000007816559,0.0003780437,0.9956347,0.0010514982,0.0006748878,0.00022493451],"about_ca_topic_score_codex":0.000034662055,"about_ca_topic_score_gemma":5.328574e-7,"teacher_disagreement_score":0.02435867,"about_ca_system_score_codex":0.000058393052,"about_ca_system_score_gemma":0.0000885087,"threshold_uncertainty_score":0.9999775},"labels":[],"label_agreement":null},{"id":"W2132633982","doi":"10.1124/mol.112.082099","title":"Control of P2X3 Channel Function by Metabotropic P2Y2 UTP Receptors in Primary Sensory Neurons","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; McGill University; AstraZeneca (Canada); Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Purinergic receptor; P2Y receptor; Ionotropic effect; Metabotropic receptor; PPADS; Receptor; Homomeric; Cell biology; Metabotropic glutamate receptor; Purinergic signalling; Biology; Neuroscience; Chemistry; Agonist; Glutamate receptor; Biochemistry; Adenosine receptor; Protein subunit","score_opus":0.007856252754626281,"score_gpt":0.24210840166502953,"score_spread":0.23425214891040325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132633982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9645472,0.017927023,0.015560665,0.00023423262,0.0009060646,0.00027233906,0.00002176013,0.000014423666,0.000516274],"genre_scores_gemma":[0.99635506,0.00020305194,0.00008635082,0.00254951,0.00031388446,0.000048456033,0.00011518914,0.000033539385,0.00029493726],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998588,0.0003051419,0.0002959201,0.000276557,0.00011520452,0.00041915712],"domain_scores_gemma":[0.99951845,0.000022641294,0.0001259746,0.00017105519,0.000052030788,0.0001098376],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002019329,0.00019089029,0.0002671802,0.00009174461,0.00003299955,0.000003449539,0.0001391515,0.00018304678,0.00012023122],"category_scores_gemma":[0.000023023113,0.00019899657,0.00010977899,0.00012945254,0.00007906279,0.0000082252545,0.00006893832,0.00016943198,0.000010705902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023498485,0.0002013044,0.0020819497,0.000022681865,0.00013071291,0.000007389574,0.00002453018,0.00048793948,0.97180897,0.000031748936,0.02467307,0.00029469703],"study_design_scores_gemma":[0.0025057239,0.00031750367,0.0015045006,0.0000042603724,0.00017182845,0.000020279818,0.000021232578,0.000105256404,0.9198141,0.000014788136,0.075274944,0.00024555586],"about_ca_topic_score_codex":0.000020855257,"about_ca_topic_score_gemma":4.5119882e-7,"teacher_disagreement_score":0.05199486,"about_ca_system_score_codex":0.000019773792,"about_ca_system_score_gemma":0.000043707485,"threshold_uncertainty_score":0.8114844},"labels":[],"label_agreement":null},{"id":"W2132698464","doi":"10.1124/mol.112.082362","title":"Induction of Multidrug Resistance Transporter ABCG2 by Prolactin in Human Breast Cancer Cells","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Abcg2; Multiple drug resistance; Prolactin; Transporter; Breast cancer; Biology; Pharmacology; Cancer research; Medicine; Cancer; Internal medicine; Drug resistance; ATP-binding cassette transporter; Gene; Hormone; Genetics","score_opus":0.007898098251346995,"score_gpt":0.29174259586760043,"score_spread":0.2838444976162534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132698464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956318,0.0012068654,0.00046424574,0.0009152403,0.0005403485,0.00056014943,0.000063014515,0.00003203954,0.0005862628],"genre_scores_gemma":[0.9979306,0.000091525726,0.00027559398,0.00048272088,0.00011876803,0.000102023805,0.000044120257,0.00003694969,0.0009176851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986842,0.000068062574,0.00037333881,0.00024770616,0.00020286771,0.00042378754],"domain_scores_gemma":[0.99951977,0.000007684847,0.00012322249,0.00014233025,0.000059258877,0.00014775776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022003036,0.00017975277,0.00036428735,0.00013431998,0.00003489775,0.0000019377856,0.000087467204,0.00015330243,0.0005499476],"category_scores_gemma":[8.123112e-7,0.00016729214,0.0000996163,0.00021952829,0.00009361383,0.00009192205,0.0000063794914,0.00030103803,0.0000048773313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074181665,0.00066252076,0.007983355,0.00021878794,0.00007951324,0.00006852503,0.000515278,0.000010895585,0.9879086,0.000043872693,0.0014195907,0.00034725602],"study_design_scores_gemma":[0.002899314,0.000034091398,0.028440047,0.00006506857,0.00020411507,0.000011388601,0.000060854527,0.000008412965,0.9640245,0.000014402694,0.0040813107,0.00015650193],"about_ca_topic_score_codex":0.00008169319,"about_ca_topic_score_gemma":0.000060196428,"teacher_disagreement_score":0.023884097,"about_ca_system_score_codex":0.00009053314,"about_ca_system_score_gemma":0.000050844257,"threshold_uncertainty_score":0.6821975},"labels":[],"label_agreement":null},{"id":"W2133284327","doi":"10.1124/mol.107.038851","title":"Enhancement of Glucose Transporter Expression of Brain Endothelial Cells by Vascular Endothelial Growth Factor Derived from Glioma Exposed to Hypoxia","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":163,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Council Canada; National Science Council","keywords":"Glucose transporter; GLUT1; Glucose Transporter Type 1; Vascular endothelial growth factor; Biology; Vascular endothelial growth factor A; Hypoxia (environmental); Transfection; Endothelium; Glucose uptake; Endocrinology; Blood–brain barrier; Internal medicine; Vascular endothelial growth factor B; Secretion; Chemistry; Cell culture; Cancer research; Medicine; Insulin; Central nervous system; VEGF receptors","score_opus":0.007399159181302822,"score_gpt":0.2495327791230125,"score_spread":0.24213361994170968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133284327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9479613,0.0024829253,0.046298925,0.00006832043,0.0015304964,0.00068869203,0.0008786933,0.000015213058,0.00007544637],"genre_scores_gemma":[0.9956747,0.0003580115,0.0017264553,0.0011506425,0.0006632721,0.00005920403,0.00022734451,0.000064823515,0.00007550772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975223,0.00019270563,0.000684068,0.00067434134,0.00036023968,0.0005663535],"domain_scores_gemma":[0.998819,0.000058216156,0.00026644825,0.0004063208,0.00017134742,0.00027866877],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002637823,0.0003720972,0.0005486459,0.00014891905,0.000045940054,0.0000068843633,0.00043674922,0.0002924357,0.00040645734],"category_scores_gemma":[0.000038656694,0.0003815699,0.00036436153,0.0001570947,0.00014659154,0.000008308817,0.00011663354,0.00014158883,0.000008366104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013110585,0.0004099686,0.000028365213,0.000039635,0.00025656552,0.00002138669,0.00041538608,0.000014610702,0.992888,0.0000031746129,0.0029524865,0.0016594176],"study_design_scores_gemma":[0.00442728,0.0004958796,0.00020303375,0.00001569842,0.00013469136,0.0000031327884,0.000053499705,0.0000035898333,0.9556114,0.000010943538,0.038697023,0.00034384243],"about_ca_topic_score_codex":0.00010880138,"about_ca_topic_score_gemma":0.000017070948,"teacher_disagreement_score":0.04771345,"about_ca_system_score_codex":0.000027384061,"about_ca_system_score_gemma":0.00010796581,"threshold_uncertainty_score":0.9998636},"labels":[],"label_agreement":null},{"id":"W2133704905","doi":"10.1124/mol.104.002246","title":"Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a Selective Inhibitor of Phosphodiesterase 7: In Vitro Studies in Human Monocytes, Lung Macrophages, and CD8+ T-Lymphocytes","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Rolipram; Proinflammatory cytokine; Tumor necrosis factor alpha; Molecular biology; T cell; CD8; Monocyte; Chemistry; Biology; Immunology; Phosphodiesterase; Pharmacology; Biochemistry; Immune system; Inflammation; Enzyme","score_opus":0.01176628024811817,"score_gpt":0.3078456498108342,"score_spread":0.296079369562716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133704905","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.976789,0.021772694,0.0004885043,0.00007347338,0.0002915705,0.00048312536,0.000036710688,0.000010458484,0.0000544826],"genre_scores_gemma":[0.9976518,0.0010918736,0.00067461794,0.0002589896,0.000061992374,0.00008175138,0.000080301594,0.0000355222,0.00006311369],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805236,0.00025813485,0.00062850764,0.0005474005,0.0001576209,0.00035598048],"domain_scores_gemma":[0.9992527,0.000052557985,0.00027283584,0.00021306681,0.00014767286,0.00006120298],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030664002,0.00031260145,0.000570322,0.00029859232,0.00005501167,0.000010813217,0.00014872539,0.00021805764,0.000003905949],"category_scores_gemma":[0.00007592961,0.00031631358,0.000117404365,0.00035272716,0.00039176943,0.000027195221,0.00023602338,0.00018278044,4.596867e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011610019,0.00034846974,0.0015126255,0.00018422824,0.00024443812,0.0000807922,0.00045448376,0.0021304355,0.9933166,0.00007742817,0.00006840076,0.00042109133],"study_design_scores_gemma":[0.006018783,0.00039591957,0.0026985537,0.00007212759,0.00007661499,0.000026501973,0.00020772072,0.00008291329,0.9897116,0.00034832399,0.00008958153,0.0002713476],"about_ca_topic_score_codex":0.00026838508,"about_ca_topic_score_gemma":0.000101690304,"teacher_disagreement_score":0.020862857,"about_ca_system_score_codex":0.00019740485,"about_ca_system_score_gemma":0.00016683075,"threshold_uncertainty_score":0.9999289},"labels":[],"label_agreement":null},{"id":"W2133873320","doi":"10.1124/mol.109.062679","title":"Correction of the ΔPhe508 Cystic Fibrosis Transmembrane Conductance Regulator Trafficking Defect by the Bioavailable Compound Glafenine","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University","funders":"Canadian Institutes of Health Research; Rosalind Franklin University of Medicine and Science; McGill University","keywords":"Cystic fibrosis transmembrane conductance regulator; Pharmacology; Chemistry; In vivo; Ex vivo; Cystic fibrosis; Cell biology; Molecular biology; In vitro; Biochemistry; Biology; Medicine; Internal medicine; Gene","score_opus":0.008611892832236987,"score_gpt":0.2889855658781945,"score_spread":0.2803736730459575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133873320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901287,0.0019861574,0.0010710141,0.002767652,0.0022027588,0.0009957588,0.00003469567,0.000046690257,0.00076659874],"genre_scores_gemma":[0.9975483,0.000032399315,0.0006203978,0.00060490315,0.00011963309,0.00007432142,0.000022187174,0.000038797527,0.00093909266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805427,0.0002713491,0.00035773724,0.00036325023,0.0005114079,0.00044199187],"domain_scores_gemma":[0.99855894,0.0005228436,0.00016245674,0.00044747491,0.0001771416,0.00013115982],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00046388275,0.00021541482,0.00037837552,0.00006879257,0.00020933864,0.000022121658,0.00043382804,0.00012558371,0.0009320709],"category_scores_gemma":[0.00029693608,0.00013565447,0.00023800363,0.00052809936,0.00084032555,0.000065920016,0.00007207257,0.0007495771,0.000021924738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006022306,0.00014924521,0.00016105434,0.00008894833,0.00014751966,0.000020429297,0.00007391239,0.00026114544,0.9769077,0.000037059897,0.019125564,0.0024251945],"study_design_scores_gemma":[0.0020655,0.00033852368,0.0008797638,0.000051648316,0.00030420377,0.00031460656,0.000032985485,0.005322743,0.93906814,0.000027787266,0.051466156,0.00012796323],"about_ca_topic_score_codex":0.00006494982,"about_ca_topic_score_gemma":0.000038091042,"teacher_disagreement_score":0.037839577,"about_ca_system_score_codex":0.000060306036,"about_ca_system_score_gemma":0.00017451828,"threshold_uncertainty_score":0.9999812},"labels":[],"label_agreement":null},{"id":"W2135020482","doi":"10.1124/mol.106.033670","title":"Activation of the Angiotensin II Type 1 Receptor Leads to Movement of the Sixth Transmembrane Domain: Analysis by the Substituted Cysteine Accessibility Method","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Transmembrane domain; Cysteine; Angiotensin II; Transmembrane protein; Chemistry; Domain (mathematical analysis); Receptor; Biophysics; Biochemistry; Biology; Mathematics; Mathematical analysis","score_opus":0.009299524320698697,"score_gpt":0.29789726092038243,"score_spread":0.28859773659968374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135020482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.895349,0.00019593915,0.102114886,0.0014389069,0.00030661278,0.00050709216,0.000026899746,0.000004283723,0.000056334473],"genre_scores_gemma":[0.9960062,0.000011192353,0.0019656373,0.0017679813,0.000058572303,0.000012651021,0.000041180047,0.000015226475,0.000121382254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836355,0.0004230609,0.00039585313,0.0003270629,0.00024826845,0.00024221258],"domain_scores_gemma":[0.99897736,0.000037849728,0.00022809833,0.00047630217,0.0002266686,0.000053742184],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010606997,0.00016412925,0.00025966586,0.000054246888,0.00015011585,0.0000059504514,0.0005295265,0.00015065442,0.00017726318],"category_scores_gemma":[0.000045559314,0.00009300508,0.000304989,0.0008575859,0.000112019035,0.000003946738,0.00018247133,0.00013760904,4.8928416e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028489265,0.00010179119,0.00023225498,0.0000113439655,0.0005013688,3.175613e-7,0.00015488332,0.0029297543,0.9945558,0.00008148616,0.0005624785,0.0005836586],"study_design_scores_gemma":[0.0004895995,0.00016810677,0.00063136104,0.000005532045,0.00031993678,7.906015e-7,0.000045925375,0.00013312827,0.99477,0.00004959086,0.0032828427,0.000103193684],"about_ca_topic_score_codex":0.00008101503,"about_ca_topic_score_gemma":0.000034605775,"teacher_disagreement_score":0.100657135,"about_ca_system_score_codex":0.000030924,"about_ca_system_score_gemma":0.00006703675,"threshold_uncertainty_score":0.3792637},"labels":[],"label_agreement":null},{"id":"W2135102015","doi":"10.1124/mol.107.034504","title":"Discovery of Osmosensitive Transcriptional Regulation of Human Cytochrome P450 3As by the Tonicity-Responsive Enhancer Binding Protein (Nuclear Factor of Activated T Cells 5)","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Chinese Academy of Agricultural Sciences","keywords":"Enhancer; Molecular biology; Biology; Transcription factor; Electrophoretic mobility shift assay; Chromatin immunoprecipitation; Transcription (linguistics); CYP3A; Transfection; Cell biology; Gene expression; Gene; Promoter; Biochemistry; Cytochrome P450","score_opus":0.008190520815117737,"score_gpt":0.27648941360681695,"score_spread":0.2682988927916992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135102015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979205,0.00019288459,0.00091246393,0.00006586525,0.000057554087,0.0004995836,0.00018620468,0.0000049267783,0.00015998146],"genre_scores_gemma":[0.9993174,0.000018576002,0.00009272856,0.00005664569,0.000054824053,0.000009705482,0.0001435932,0.00002546373,0.00028107665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998766,0.00018603457,0.0003783879,0.00026104864,0.00018394324,0.00022460801],"domain_scores_gemma":[0.9992616,0.000029175717,0.0003197463,0.00018145323,0.00017064004,0.000037338574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020758437,0.00016358992,0.00025431422,0.00008173497,0.00005900107,0.0000037525358,0.00015700996,0.00015904914,0.00007685364],"category_scores_gemma":[0.000016257323,0.00014113326,0.00015137777,0.00014992122,0.0003153401,0.000011027065,0.00006404819,0.00012715855,0.000001245091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080263475,0.00019373842,0.0000052739256,0.000043343367,0.00033302972,0.0000074115374,0.00015587128,0.000022213642,0.9978324,0.00029215883,0.00021626287,0.000095645984],"study_design_scores_gemma":[0.00090007036,0.00048864173,0.00060984277,0.000020116591,0.000073003306,0.0000069967014,0.00008898166,0.00000555588,0.99724257,0.00003228735,0.00040419004,0.0001277213],"about_ca_topic_score_codex":0.000019505202,"about_ca_topic_score_gemma":0.0000025058082,"teacher_disagreement_score":0.001396851,"about_ca_system_score_codex":0.000029017556,"about_ca_system_score_gemma":0.00007448991,"threshold_uncertainty_score":0.57552475},"labels":[],"label_agreement":null},{"id":"W2135488334","doi":"10.1124/mol.114.097337","title":"Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Functional selectivity; Angiotensin II; MAPK/ERK pathway; Signal transduction; Receptor; Cell biology; Angiotensin II receptor type 1; Protein kinase C; Heterotrimeric G protein; G protein-coupled receptor; Gq alpha subunit; Chemistry; Biology; G protein; Biochemistry","score_opus":0.017882987552740526,"score_gpt":0.2624441196140655,"score_spread":0.24456113206132496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135488334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98482674,0.00023431052,0.013768195,0.00016214781,0.00061086955,0.00030341046,0.000016150028,0.000014450934,0.00006371821],"genre_scores_gemma":[0.9979908,0.000029368508,0.00084782334,0.00060108374,0.00013283372,0.000042136628,0.00023072121,0.000036858484,0.00008835972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841714,0.00027078006,0.00034295162,0.00043988464,0.0002016015,0.0003276492],"domain_scores_gemma":[0.99926025,0.0000068964478,0.00016951351,0.00018950576,0.00023823795,0.00013557155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039210936,0.00020975243,0.00028484184,0.00013934252,0.00004527319,0.000007985568,0.00015958233,0.00025340167,0.00012905347],"category_scores_gemma":[0.00006148741,0.00023074009,0.00011194976,0.00024683576,0.00006850466,0.000010320435,0.00016322173,0.00014003075,0.00000769752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028214662,0.0001794842,0.0014332575,0.000010614978,0.000055598237,0.00002804466,0.000056862013,0.00032570426,0.9964338,0.000044206798,0.00040441845,0.00074585935],"study_design_scores_gemma":[0.0014456881,0.00046765595,0.00073235645,0.000010121031,0.00002881631,0.000012815849,0.000016057047,0.00064954854,0.9924659,0.00007804391,0.0038674013,0.00022556621],"about_ca_topic_score_codex":0.000022389704,"about_ca_topic_score_gemma":0.000011811899,"teacher_disagreement_score":0.013164068,"about_ca_system_score_codex":0.00004854777,"about_ca_system_score_gemma":0.00019464194,"threshold_uncertainty_score":0.9409308},"labels":[],"label_agreement":null},{"id":"W2135610502","doi":"10.1124/mol.114.092478","title":"Synergy-Based Small-Molecule Screen Using a Human Lung Epithelial Cell Line Yields ΔF508-CFTR Correctors That Augment VX-809 Maximal Efficacy","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institute of Biomedical Imaging and Bioengineering; National Eye Institute; Cystic Fibrosis Foundation; University of California, San Francisco; National Institutes of Health","keywords":"Cystic fibrosis transmembrane conductance regulator; ΔF508; Chemistry; Cystic fibrosis; Chloride channel; Cell culture; Mutation; Molecular biology; Cell biology; Biochemistry; Biology; Genetics; Gene","score_opus":0.02854122652544669,"score_gpt":0.33934351462802653,"score_spread":0.3108022881025798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135610502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9121439,0.0005444362,0.08346078,0.0008826721,0.0006283381,0.0011880933,0.00004006107,0.00018032918,0.00093141146],"genre_scores_gemma":[0.98846227,0.000009473835,0.0075095254,0.0027713953,0.00047094308,0.00007775327,0.00022339195,0.00012824436,0.00034703102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962651,0.0005458864,0.0005207244,0.00084703136,0.0006948628,0.0011263653],"domain_scores_gemma":[0.9981127,0.00031329674,0.00022156889,0.0005462047,0.00019314114,0.0006131257],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004961174,0.0005026332,0.00074138865,0.00041607808,0.00025724043,0.00004982499,0.00043094382,0.00025213647,0.0009982028],"category_scores_gemma":[0.00018106584,0.00048607535,0.00032720625,0.00038199103,0.0003311823,0.000060521004,0.00026186768,0.0007321684,0.000055071145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090694136,0.00077948096,0.00059684983,0.00018094658,0.00019154318,0.00073288305,0.000056384833,0.005283286,0.9885432,0.000041000465,0.0012765136,0.0014109329],"study_design_scores_gemma":[0.008515234,0.0015448135,0.00075855525,0.00011448419,0.0005258235,0.000059293918,0.000015820824,0.057136223,0.9262185,0.00001418023,0.0046652686,0.00043176877],"about_ca_topic_score_codex":0.0002586212,"about_ca_topic_score_gemma":0.000016628428,"teacher_disagreement_score":0.07631836,"about_ca_system_score_codex":0.00032971698,"about_ca_system_score_gemma":0.0003031093,"threshold_uncertainty_score":0.999915},"labels":[],"label_agreement":null},{"id":"W2135695151","doi":"10.1124/mol.113.088963","title":"Salicylate, a Catalytic Inhibitor of Topoisomerase II, Inhibits DNA Cleavage and Is Selective for the α Isoform","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Topoisomerase; Gene isoform; Etoposide; DNA; Enzyme; Biochemistry; Chemistry; DNA damage; Biology; Gene; Chemotherapy","score_opus":0.007656464470815724,"score_gpt":0.2642243312301065,"score_spread":0.2565678667592908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135695151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928958,0.0020044602,0.0019967011,0.0014518187,0.00027309536,0.001082853,0.00007106937,0.0000093122335,0.00021492384],"genre_scores_gemma":[0.9933318,0.000288668,0.00013699585,0.0052270326,0.0001528798,0.00032713183,0.000042797903,0.00003264479,0.0004600438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990487,0.00003196132,0.00021813264,0.0003194153,0.0000840521,0.00029770055],"domain_scores_gemma":[0.9994463,0.000028458247,0.00010514738,0.0001976114,0.00014141641,0.0000810932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012818033,0.00017537164,0.00018334179,0.00003619159,0.00013844064,0.000014071416,0.00015737907,0.0001373745,0.000038237715],"category_scores_gemma":[0.0000142627,0.00014193068,0.00010472445,0.00009723775,0.00013028145,0.000005817328,0.00016926478,0.00009253225,0.000003347929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001142382,0.00006410887,0.000008692794,0.00002699552,0.00022970073,0.0000012477864,0.00022412204,0.000006512329,0.9810354,0.0001679124,0.01260061,0.0055204323],"study_design_scores_gemma":[0.0014354317,0.0007376042,0.000053847416,0.000004382413,0.000120084886,0.000019841327,0.00006463412,0.0002914697,0.95824593,0.00044404232,0.03842294,0.00015977316],"about_ca_topic_score_codex":0.00006470288,"about_ca_topic_score_gemma":0.000012173329,"teacher_disagreement_score":0.025822328,"about_ca_system_score_codex":0.000018111788,"about_ca_system_score_gemma":0.00007566793,"threshold_uncertainty_score":0.5787765},"labels":[],"label_agreement":null},{"id":"W2136656278","doi":"10.1124/mol.107.040725","title":"Structural Analog of Sildenafil Identified as a Novel Corrector of the F508del-CFTR Trafficking Defect","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; William Osler Health System","funders":"McGill University; Pfizer","keywords":"Cystic fibrosis transmembrane conductance regulator; Brefeldin A; Endoplasmic reticulum; Cystic fibrosis; Chemistry; Baby hamster kidney cell; Chloride channel; Ciliogenesis; Cell biology; Molecular biology; Biochemistry; Biology; Cilium; Cell; Golgi apparatus; Genetics","score_opus":0.016112428823578603,"score_gpt":0.35336929997418726,"score_spread":0.33725687115060865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136656278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99513566,0.0008536428,0.0019092123,0.00019275164,0.00067685865,0.00035728863,0.000016856591,0.000023943958,0.0008338001],"genre_scores_gemma":[0.9983886,0.000010297333,0.00093454943,0.00036360606,0.00007156913,0.000009642252,0.00000908024,0.00002465105,0.00018798662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823993,0.000112940135,0.0004441079,0.00027201907,0.00050754746,0.0004234786],"domain_scores_gemma":[0.9988309,0.00030979502,0.0002135555,0.0002742906,0.00023411385,0.00013735953],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004510794,0.00016003315,0.00039898366,0.0001869719,0.00005414559,0.000005138713,0.0002832967,0.000089802554,0.00034798225],"category_scores_gemma":[0.00048201188,0.00011839108,0.00028793907,0.00050097366,0.0003931608,0.000039169016,0.00013282303,0.00031546105,0.000006467266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007436366,0.00010519369,0.0015553329,0.00016411647,0.0002456706,0.000107220156,0.00016325284,0.0003837623,0.99257874,0.0001311985,0.00030327638,0.003518611],"study_design_scores_gemma":[0.0026754346,0.0003165199,0.020071773,0.00006514236,0.00026034017,0.00021737015,0.00009410081,0.0009535133,0.9746821,0.0000452957,0.0005180737,0.00010036254],"about_ca_topic_score_codex":0.00009778619,"about_ca_topic_score_gemma":0.000036726968,"teacher_disagreement_score":0.01851644,"about_ca_system_score_codex":0.00008461747,"about_ca_system_score_gemma":0.00019387354,"threshold_uncertainty_score":0.4827848},"labels":[],"label_agreement":null},{"id":"W2136928110","doi":"10.1124/mol.62.5.1011","title":"Haptenation of Sulfonamide Reactive Metabolites to Cellular Proteins","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Western Ontario; Western University","funders":"","keywords":"Sulfonamide; Hapten; Chemistry; Immune system; Pathogenesis; Toxicity; Hydroxylamine; Antibody; Pharmacology; Biochemistry; Immunology; Biology; Stereochemistry","score_opus":0.021402346676891643,"score_gpt":0.29228977901571324,"score_spread":0.2708874323388216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136928110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9536902,0.00039453013,0.0028139034,0.0030021232,0.00032853658,0.0012419677,0.000014234495,0.00008138908,0.03843316],"genre_scores_gemma":[0.99529916,0.000024409379,0.0021990763,0.0011886377,0.000092651826,0.00012465524,0.000015340458,0.00003196801,0.0010240808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886966,0.00009293504,0.00025581312,0.0002821017,0.00023584056,0.00026362977],"domain_scores_gemma":[0.99923766,0.00004345687,0.00010568323,0.00021088615,0.00021782634,0.00018447572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117585776,0.00014929193,0.0003133654,0.00030127575,0.000037350885,0.0000037466593,0.000085324784,0.00009325698,0.00023877849],"category_scores_gemma":[0.00011959597,0.00014938756,0.00012390371,0.0003830872,0.000060906346,0.00006936119,0.000045990473,0.00021588271,0.00023122098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019385074,0.00038528343,0.0000481015,0.0000270333,0.00021469667,0.00019200462,0.00018247035,0.000069962014,0.9901458,0.00093545456,0.00023992218,0.0075398567],"study_design_scores_gemma":[0.0011645039,0.00007743629,0.0011838367,0.000014047603,0.00035272204,0.000053245447,0.000049647828,0.0006085397,0.94971156,0.00008346502,0.046584204,0.000116778],"about_ca_topic_score_codex":0.000046455,"about_ca_topic_score_gemma":0.0000015296616,"teacher_disagreement_score":0.04634428,"about_ca_system_score_codex":0.00011461087,"about_ca_system_score_gemma":0.00004287018,"threshold_uncertainty_score":0.60918474},"labels":[],"label_agreement":null},{"id":"W2137007692","doi":"10.1124/mol.106.031682","title":"Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions with a Potassium Ion in the Selectivity Filter","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Potassium channel; Potassium; Selectivity; Chemistry; Biophysics; Ion channel; Biochemistry; Biology; Receptor; Organic chemistry","score_opus":0.011628766136750285,"score_gpt":0.2857259813262618,"score_spread":0.2740972151895115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137007692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862857,0.00009981947,0.010965553,0.00094122713,0.0006286743,0.00047781118,0.0000034485734,0.000015933287,0.00058182277],"genre_scores_gemma":[0.99750835,0.000020011106,0.000092872426,0.0016159273,0.0003123868,0.00010822999,0.00012804025,0.000024251642,0.000189916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852824,0.00026885484,0.00024481316,0.0003706201,0.00014587588,0.00044159102],"domain_scores_gemma":[0.99958074,0.00005474102,0.00009364091,0.00015694925,0.00006147801,0.000052423788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005641276,0.00018697759,0.00015133632,0.00029091383,0.00008621263,0.000026382175,0.00015340086,0.00012791889,0.00004433661],"category_scores_gemma":[0.000038763486,0.00015092692,0.000057199275,0.00050652557,0.000069311216,0.000015175014,0.000042730633,0.00030228583,0.0000093492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003748314,0.00020834924,0.0019838815,0.000012701716,0.000038778446,0.000079726175,0.00032304905,0.0010258112,0.99427414,0.00004280012,0.0012570992,0.00037882273],"study_design_scores_gemma":[0.0017540683,0.0005107493,0.0075142304,0.000013535609,0.000025918116,0.00013971326,0.00027986846,0.0015251599,0.9795514,0.00005311735,0.0083923675,0.00023987133],"about_ca_topic_score_codex":0.000037092595,"about_ca_topic_score_gemma":0.00030043913,"teacher_disagreement_score":0.014722749,"about_ca_system_score_codex":0.000088810724,"about_ca_system_score_gemma":0.000067436675,"threshold_uncertainty_score":0.6154621},"labels":[],"label_agreement":null},{"id":"W2137376813","doi":"10.1124/mol.113.086603","title":"Paradoxical Activation of an Inwardly Rectifying Potassium Channel Mutant by Spermine: \"(B)locking\" Open the Bundle Crossing Gate","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Potassium channel; Spermine; Mutant; Chemistry; Bundle; Biophysics; Biochemistry; Materials science; Biology; Gene; Enzyme","score_opus":0.01890600162903237,"score_gpt":0.3051909221871796,"score_spread":0.2862849205581472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137376813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98814535,0.00010219563,0.008511401,0.001402502,0.00069361745,0.00063538895,0.000010582723,0.000016956355,0.00048199279],"genre_scores_gemma":[0.99707514,0.000017340024,0.00016505846,0.0017643808,0.00031927467,0.000112256224,0.00021568645,0.00003191874,0.00029894637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986274,0.00026580697,0.00029167772,0.0003824001,0.000147031,0.00028565025],"domain_scores_gemma":[0.9992879,0.000022424203,0.00018477972,0.00025413884,0.00015261886,0.000098121156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028195736,0.00017848347,0.0001798445,0.000049709586,0.0002609335,0.000117077056,0.00035961627,0.00019060905,0.00016659556],"category_scores_gemma":[0.000055442684,0.00014602096,0.000075578275,0.0001569987,0.00018825181,0.00002680941,0.00020795735,0.00014911221,0.000011451026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001310075,0.00017013539,0.00003110463,0.000009540133,0.000055973098,0.0000018993994,0.00009200811,0.0017190722,0.9918724,0.000025749674,0.0036537212,0.0022374035],"study_design_scores_gemma":[0.00093436753,0.00033527135,0.0002928175,0.0000059809,0.000026827534,0.000029288627,0.00011077762,0.010444243,0.97289723,0.00012548502,0.014621322,0.0001763754],"about_ca_topic_score_codex":0.00013163665,"about_ca_topic_score_gemma":0.000002403775,"teacher_disagreement_score":0.018975142,"about_ca_system_score_codex":0.000027906844,"about_ca_system_score_gemma":0.00008181267,"threshold_uncertainty_score":0.5954562},"labels":[],"label_agreement":null},{"id":"W2137736044","doi":"10.1124/mol.61.4.795","title":"Heterogeneous Nuclear Ribonucleoprotein A1 and Regulation of the Xenobiotic-Inducible Gene<i>Cyp2a5</i>","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Molecular biology; Heterogeneous nuclear ribonucleoprotein; Messenger RNA; Gene; Biology; Gene expression; Immunoprecipitation; Ribonucleoprotein; RNA; Heterogeneous ribonucleoprotein particle; Biochemistry","score_opus":0.010365803122714214,"score_gpt":0.2428051757284557,"score_spread":0.2324393726057415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137736044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969298,0.0012800017,0.00015755484,0.0006158806,0.00011742609,0.00033291962,0.000008265477,0.000010133975,0.0005479695],"genre_scores_gemma":[0.99776405,0.00016834195,0.00033381485,0.00086998596,0.00008096745,0.000011492885,0.0000063864113,0.000029982491,0.0007349938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988615,0.00017308623,0.00019045563,0.00032603563,0.00015021928,0.00029871942],"domain_scores_gemma":[0.99941593,0.0000075326257,0.000086309934,0.00032829613,0.00006594314,0.000096008574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014109546,0.00013650184,0.00014308392,0.00004362532,0.000118410746,0.000014454544,0.00024088603,0.00014066388,0.00016896421],"category_scores_gemma":[0.000032055712,0.00011499757,0.000093976385,0.00011433783,0.00018789619,0.0000038707603,0.00024246528,0.00012633107,0.000012830261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004048141,0.000056115212,0.00016649159,0.000018417957,0.00006980496,0.000011466072,0.00002185144,0.00027265947,0.9962663,0.000058203852,0.001176865,0.0018413588],"study_design_scores_gemma":[0.0006712783,0.00020977392,0.00051418506,0.0000053220015,0.000030157309,0.00007889258,0.0000056662725,0.0023242608,0.98538417,0.000028074015,0.010628682,0.00011956494],"about_ca_topic_score_codex":0.000022875332,"about_ca_topic_score_gemma":0.0000045904326,"teacher_disagreement_score":0.010882141,"about_ca_system_score_codex":0.000012689115,"about_ca_system_score_gemma":0.000019916086,"threshold_uncertainty_score":0.4689465},"labels":[],"label_agreement":null},{"id":"W2137872660","doi":"10.1124/mol.108.047019","title":"Direct Modulation of P2X1 Receptor-Channels by the Lipid Phosphatidylinositol 4,5-Bisphosphate","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Heart, Lung, and Blood Institute","keywords":"Wortmannin; Phosphatidylinositol; Phospholipase C; Phosphatidylinositol 4,5-bisphosphate; Biophysics; Biology; Receptor; Endocrinology; Internal medicine; Biochemistry; Signal transduction; Medicine","score_opus":0.009375140814803593,"score_gpt":0.2495843467560929,"score_spread":0.2402092059412893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137872660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98170745,0.0112788025,0.004398755,0.00048315577,0.00076553295,0.00033138366,0.000024782126,0.000022642213,0.0009874852],"genre_scores_gemma":[0.99610233,0.00073992764,0.0001988292,0.0011184113,0.00034539172,0.000055216766,0.00016362141,0.000036518886,0.0012397685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986466,0.00018208302,0.0003205439,0.0003631543,0.00017851511,0.00030911382],"domain_scores_gemma":[0.999297,0.000031164924,0.00017924042,0.00027120404,0.00013991138,0.00008143279],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017116866,0.0002123238,0.00022832587,0.000035892208,0.00015359934,0.0000069211633,0.00031006554,0.00016970243,0.00018362059],"category_scores_gemma":[0.00003300301,0.0001776699,0.00014751668,0.00016733575,0.00018912631,0.0000060313023,0.00011821465,0.00012350632,0.000016971699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010962265,0.0000773714,0.00034712086,0.000008895749,0.00012573463,0.00001034089,0.00007106736,0.0027672409,0.8007758,0.000026970534,0.19543268,0.00024712968],"study_design_scores_gemma":[0.0007619167,0.00018673536,0.000109870634,0.0000044520257,0.000045206274,0.000033532695,0.000013580172,0.0004684446,0.90124893,0.000010506154,0.096936956,0.00017986532],"about_ca_topic_score_codex":0.000045847384,"about_ca_topic_score_gemma":2.5316e-7,"teacher_disagreement_score":0.1004731,"about_ca_system_score_codex":0.00001307321,"about_ca_system_score_gemma":0.00006269075,"threshold_uncertainty_score":0.72451687},"labels":[],"label_agreement":null},{"id":"W2137900887","doi":"10.1124/mol.113.087783","title":"The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":202,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research","keywords":"Agonism; GPR120; Agonist; Pharmacology; Partial agonist; Receptor; Chemistry; G protein-coupled receptor; Biochemistry; Medicine; Political science","score_opus":0.01179449446762494,"score_gpt":0.251569769564625,"score_spread":0.23977527509700008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137900887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98170245,0.009264983,0.0016715433,0.0052024024,0.000672167,0.0011946935,0.00004311315,0.000011723511,0.00023693434],"genre_scores_gemma":[0.99495673,0.0027968097,0.000674906,0.0011541029,0.00013483469,0.00018004296,0.000010354472,0.00003380455,0.000058390517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979268,0.00056615815,0.00040974544,0.0004696177,0.00018600855,0.00044171835],"domain_scores_gemma":[0.9989058,0.000052623735,0.00026763015,0.00033062213,0.00023542199,0.00020791794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004439637,0.00028431776,0.00034042832,0.00005708954,0.00029272874,0.000031116677,0.00050323235,0.00022885806,0.00011816253],"category_scores_gemma":[0.00005070582,0.00019604049,0.00013871398,0.000119209064,0.00049217284,0.000010299264,0.00049751566,0.00024015248,0.0000018504053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017681555,0.000101236714,0.00008227824,0.000037865255,0.00042020157,0.0000041341536,0.00016798843,0.00003920963,0.9876635,0.0002568961,0.0012651127,0.009784738],"study_design_scores_gemma":[0.0010496962,0.0007009644,0.001348587,0.00001031649,0.00016424539,0.000050761704,0.00033234598,0.00016335459,0.993526,0.0008624355,0.0015826611,0.0002086332],"about_ca_topic_score_codex":0.000062681174,"about_ca_topic_score_gemma":0.0000146148595,"teacher_disagreement_score":0.013254315,"about_ca_system_score_codex":0.000018379009,"about_ca_system_score_gemma":0.00018778117,"threshold_uncertainty_score":0.7994299},"labels":[],"label_agreement":null},{"id":"W2138498861","doi":"10.1124/mol.111.073460","title":"Interactions of Key Charged Residues Contributing to Selective Block of Neuronal Sodium Channels by μ-Conotoxin KIIIA","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute","funders":"Canadian Institutes of Health Research","keywords":"Sodium channel; Key (lock); Block (permutation group theory); Conotoxin; Chemistry; Sodium; Neuroscience; Biophysics; Computer science; Biology; Biochemistry; Computer security; Peptide; Mathematics","score_opus":0.012693264311832035,"score_gpt":0.28643256468019923,"score_spread":0.2737393003683672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138498861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99433,0.00027979797,0.0026385547,0.00022035796,0.0005997219,0.00059462275,0.00009708516,0.000017492128,0.0012223598],"genre_scores_gemma":[0.9981847,0.00003082669,0.00055083196,0.0006768278,0.00013749227,0.000085135856,0.000057552385,0.000039287446,0.0002373683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811673,0.0003023078,0.00048702833,0.00046338767,0.00013229711,0.000498274],"domain_scores_gemma":[0.99896663,0.000036523452,0.0002926472,0.0002372678,0.0003284453,0.00013849071],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031736324,0.0002326817,0.00038170256,0.00010608745,0.00006832809,0.0000037765467,0.00033357443,0.00013913706,0.00016388734],"category_scores_gemma":[0.0001737462,0.0002544703,0.00015465973,0.00019567763,0.00011923994,0.000005271859,0.00034706006,0.0002139658,0.000013334174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043049868,0.00039742573,0.0013501919,0.000015133899,0.00033622712,0.000001658257,0.00034703352,0.000024477677,0.9877247,0.0000283339,0.009197482,0.00014684365],"study_design_scores_gemma":[0.0013255865,0.0007841286,0.00035650967,0.00000834066,0.00009596656,0.000013707283,0.000056642337,0.000026987303,0.98780274,0.000014152014,0.009313292,0.00020193528],"about_ca_topic_score_codex":0.00007298898,"about_ca_topic_score_gemma":0.0000115637895,"teacher_disagreement_score":0.0038546696,"about_ca_system_score_codex":0.000025368436,"about_ca_system_score_gemma":0.00010257364,"threshold_uncertainty_score":0.99999076},"labels":[],"label_agreement":null},{"id":"W2138610759","doi":"10.1124/mol.107.044214","title":"The RGS2 Gene Product from a Candidate Hypertension Allele Shows Decreased Plasma Membrane Association and Inhibition of Gq","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs","funders":"","keywords":"RGS2; Missense mutation; Mutant; Allele; Mutation; Bilayer; Biology; Population; Receptor; Chemistry; Cell biology; Biophysics; Biochemistry; G protein; Gene; Medicine; Membrane; GTPase-activating protein","score_opus":0.008667046327497853,"score_gpt":0.2209787069717483,"score_spread":0.21231166064425044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138610759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99676037,0.0015578464,0.0007455676,0.0003653857,0.00022201781,0.0002580966,0.000030089343,0.000010196545,0.000050456656],"genre_scores_gemma":[0.9970527,0.001290387,0.00061287667,0.00047001845,0.00016597484,0.000032373377,0.00023972862,0.000020996595,0.00011490979],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988637,0.00019945316,0.00022773197,0.00032573906,0.00015632498,0.00022705134],"domain_scores_gemma":[0.99944,0.000035595505,0.000161654,0.00015634607,0.00013205965,0.00007431562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002374547,0.00014013892,0.00018036537,0.000029108416,0.00018007624,0.000009413011,0.00008746624,0.00013305842,0.00007123148],"category_scores_gemma":[0.00006963982,0.000115732284,0.00006896379,0.000059182825,0.00006647448,0.0000044711737,0.0000762965,0.000096308606,0.0000027821773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019647887,0.000049385504,0.00023902844,0.00000505239,0.00014554769,0.000032562093,0.000037049416,0.00009099104,0.99706244,0.0000102431995,0.0016462369,0.0004849941],"study_design_scores_gemma":[0.0012489967,0.00013771353,0.00020506131,0.000003292564,0.000073229916,0.000033728502,0.000013448835,0.00076148985,0.99173754,0.000051470826,0.0056070006,0.00012700679],"about_ca_topic_score_codex":0.000107365595,"about_ca_topic_score_gemma":0.00002154826,"teacher_disagreement_score":0.00532487,"about_ca_system_score_codex":0.000023294691,"about_ca_system_score_gemma":0.00007015472,"threshold_uncertainty_score":0.47194254},"labels":[],"label_agreement":null},{"id":"W2139299435","doi":"10.1124/mol.105.012229","title":"D1 and D2 Dopamine Receptors Form Heterooligomers and Cointernalize after Selective Activation of Either Receptor","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Receptor; Dopamine receptor D2; Dopamine receptor; Dopamine; D2-like receptor; Dopamine receptor D1; Chemistry; D1-like receptor; Neuroscience; Pharmacology; Psychology; Biology; Biochemistry","score_opus":0.004676035901442749,"score_gpt":0.24651932449207614,"score_spread":0.2418432885906334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139299435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938643,0.00072523736,0.00443266,0.00027525303,0.00017745822,0.00024420815,0.000008844412,0.000009768169,0.00026224484],"genre_scores_gemma":[0.99640065,0.00031269607,0.0019337285,0.00079160475,0.00016662492,0.00005198081,0.000025747164,0.00003235566,0.00028462664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899864,0.000093057,0.00022688524,0.000351546,0.00009605985,0.00023378043],"domain_scores_gemma":[0.9995855,0.000013306769,0.00011696572,0.00010588905,0.00008441378,0.00009391668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014446242,0.00018454027,0.000201841,0.000075207885,0.000038132162,0.0000115067905,0.000082301965,0.00015236631,0.00042282778],"category_scores_gemma":[0.000017615008,0.00017922083,0.00006244324,0.000053490057,0.00010371807,0.00001164175,0.00009586232,0.000105931016,0.0000036041213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038945625,0.000048246122,0.00041045857,0.00002013439,0.00014638645,0.0000020120144,0.00012201665,0.000027451764,0.99087024,0.000042395342,0.0004921437,0.007429068],"study_design_scores_gemma":[0.0010446465,0.00043558492,0.00016682054,0.000012551623,0.00004115012,0.000018619348,0.00003869077,0.00013367407,0.9680602,0.000036242134,0.02983136,0.00018045255],"about_ca_topic_score_codex":0.000014008187,"about_ca_topic_score_gemma":0.000003790921,"teacher_disagreement_score":0.029339215,"about_ca_system_score_codex":0.000023389102,"about_ca_system_score_gemma":0.000022671766,"threshold_uncertainty_score":0.73084134},"labels":[],"label_agreement":null},{"id":"W2139364634","doi":"10.1124/mol.109.055509","title":"Agonist-Biased Signaling via Proteinase Activated Receptor-2: Differential Activation of Calcium and Mitogen-Activated Protein Kinase Pathways","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; University of Calgary","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Canadian Association of Gastroenterology","keywords":"Agonist; Receptor; Protein kinase A; Signal transduction; Kinase; Biology; Molecular biology; Stereochemistry; Biochemistry; Chemistry","score_opus":0.014341586345342628,"score_gpt":0.25809703719898835,"score_spread":0.24375545085364572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139364634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9611754,0.00018161631,0.037008848,0.0001971348,0.00022260545,0.001107516,0.00002311434,0.00004176345,0.000041994255],"genre_scores_gemma":[0.99772674,0.000014156484,0.0012436309,0.00031055318,0.00019248025,0.00011518089,0.0002898947,0.000047955953,0.000059436486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793,0.00032967026,0.00043502075,0.0006294336,0.00022465736,0.00045121324],"domain_scores_gemma":[0.9990405,0.000014815603,0.0003048214,0.00025656767,0.00019800261,0.00018529141],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018262393,0.00036603864,0.00037556107,0.00013018386,0.00014983526,0.00002739175,0.00020798942,0.000359407,0.00031436404],"category_scores_gemma":[0.000057198682,0.0003733913,0.0001485989,0.00020033478,0.00009649469,0.000015586234,0.00008772288,0.00024904942,0.0000027989977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010713474,0.00026543686,0.0000051898755,0.00004625903,0.00014120579,0.000016984153,0.00007743608,0.0001023314,0.99303293,0.000085667314,0.00008822593,0.0050670058],"study_design_scores_gemma":[0.0021928072,0.0010969557,0.000025363153,0.000040220144,0.000058001588,0.000007918582,0.00003111954,0.00026271158,0.9949204,0.00015382466,0.0008262819,0.00038442557],"about_ca_topic_score_codex":0.000025636515,"about_ca_topic_score_gemma":3.8522177e-7,"teacher_disagreement_score":0.036551304,"about_ca_system_score_codex":0.000039229268,"about_ca_system_score_gemma":0.00010537653,"threshold_uncertainty_score":0.9998718},"labels":[],"label_agreement":null},{"id":"W2139381664","doi":"10.1124/mol.65.1.149","title":"Proteinase-Activated Receptor-2: Key Role of Amino-Terminal Dipeptide Residues of the Tethered Ligand for Receptor Activation","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Ligand (biochemistry); Stereochemistry; Peptide sequence; Amino acid; Receptor; Chemistry; Biochemistry","score_opus":0.016695427521066838,"score_gpt":0.29127496997785646,"score_spread":0.2745795424567896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139381664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949948,0.000073245974,0.0012214484,0.001591961,0.00018883319,0.0016172684,0.000018027855,0.00003396866,0.0002604324],"genre_scores_gemma":[0.99582756,0.000010151301,0.0032568723,0.000482973,0.00007270685,0.0001618569,0.000033079898,0.000033135228,0.00012168262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887717,0.00011824718,0.00035185346,0.00023215527,0.00021786317,0.00020271404],"domain_scores_gemma":[0.99911004,0.000046809626,0.00031231262,0.00022437701,0.00023917505,0.00006730445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017692176,0.00015442549,0.00035436096,0.000100180594,0.00006415982,0.0000038608287,0.00013742525,0.00015131601,0.00014008558],"category_scores_gemma":[0.00009800773,0.00012246103,0.00015275831,0.0002506261,0.00011729817,0.000050880437,0.000044947377,0.0001527793,0.0000043754253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071886065,0.000388602,0.00013095957,0.000112648806,0.00018313677,0.0000010780824,0.00035469478,0.000058991605,0.9954927,0.0010282091,0.00017048337,0.0013596639],"study_design_scores_gemma":[0.00408402,0.00067900936,0.0013144909,0.00014286657,0.00017987666,0.000005553144,0.000118997625,0.000027442144,0.99053437,0.0011288794,0.0016783085,0.00010620056],"about_ca_topic_score_codex":0.000045020566,"about_ca_topic_score_gemma":0.0000026344906,"teacher_disagreement_score":0.004958316,"about_ca_system_score_codex":0.00006965387,"about_ca_system_score_gemma":0.00016838331,"threshold_uncertainty_score":0.4993816},"labels":[],"label_agreement":null},{"id":"W2139953951","doi":"10.1124/mol.62.3.654","title":"Characterization and Comparison of RGS2 and RGS4 as GTPase-Activating Proteins for m2 Muscarinic Receptor-Stimulated Gi","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"RGS2; Regulator of G protein signaling; G protein; GTPase-activating protein; Muscarinic acetylcholine receptor; GTPase; Biophysics; Biology; Carbachol; Cell biology; GTP'; Chemistry; Molecular biology; Biochemistry; Receptor","score_opus":0.02050622333406117,"score_gpt":0.29827134178989223,"score_spread":0.2777651184558311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139953951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9660528,0.00075284677,0.032120157,0.00016172344,0.00016521479,0.00065527024,0.000020338373,0.000014522229,0.00005715182],"genre_scores_gemma":[0.9963596,0.00014224305,0.00273814,0.00026345198,0.00009401999,0.00008925825,0.00015980993,0.000033082662,0.000120410165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893427,0.00009957095,0.0002920958,0.00036362713,0.00008208806,0.00022832387],"domain_scores_gemma":[0.9994909,0.000022173565,0.00018883208,0.000112947506,0.00009994841,0.00008520107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014124437,0.00017061442,0.0002563786,0.000057823774,0.00009490589,0.000016414877,0.00008520034,0.00020748774,0.00023796537],"category_scores_gemma":[0.00005865935,0.0001812343,0.000056599438,0.00007418188,0.000070664384,0.000007215413,0.000083006795,0.00010398783,0.0000019552958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011013553,0.00008766291,0.00027577588,0.000060346087,0.000091884554,0.0000014621365,0.0001448803,0.000062833744,0.9893735,0.00007053385,0.000099212826,0.009621757],"study_design_scores_gemma":[0.0012632732,0.00073522597,0.00011973467,0.0000142762565,0.000044113272,0.0000074685154,0.000031544616,0.0075957426,0.98237646,0.000024663103,0.0076048896,0.00018260743],"about_ca_topic_score_codex":0.000009735879,"about_ca_topic_score_gemma":9.640422e-7,"teacher_disagreement_score":0.030306807,"about_ca_system_score_codex":0.000008966708,"about_ca_system_score_gemma":0.000013984521,"threshold_uncertainty_score":0.739052},"labels":[],"label_agreement":null},{"id":"W2140404076","doi":"10.1124/mol.105.011494","title":"Pharmacological Telomerase Inhibition Can Sensitize Drug-Resistant and Drug-Sensitive Cells to Chemotherapeutic Treatment","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Telomerase; Telomere; Drug; Cancer cell; Drug resistance; Ribonucleoprotein; Cancer research; Pharmacology; Biology; Telomerase reverse transcriptase; Cancer; Chemistry; Biochemistry; DNA; RNA; Genetics","score_opus":0.011768144283423296,"score_gpt":0.2861854120340916,"score_spread":0.27441726775066827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140404076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9718631,0.0005638652,0.00012642167,0.025126902,0.0002858207,0.0013623061,0.000046515677,0.00017057417,0.00045452063],"genre_scores_gemma":[0.96111184,0.00039851127,0.0013953558,0.035457533,0.00040847133,0.000101358535,0.000043282063,0.000059725255,0.0010239496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974549,0.0003090799,0.00042369196,0.0007922882,0.0002885359,0.00073154777],"domain_scores_gemma":[0.99871856,0.00011988376,0.00010050868,0.00021412424,0.00015389449,0.0006930245],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020165175,0.00046912162,0.0006486566,0.0002791961,0.0001681776,0.000026287149,0.00006889152,0.00013319212,0.00030504618],"category_scores_gemma":[0.000013615591,0.0004182305,0.0001585887,0.00034383495,0.0002043921,0.000053101605,0.00007364107,0.00028394253,0.00013805291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011286408,0.00065187435,0.00005852583,0.00003084798,0.00030846318,0.0022831524,0.0012552454,0.00006838123,0.9716575,0.0000221089,0.0043837577,0.018151488],"study_design_scores_gemma":[0.0054724333,0.0005349187,0.0007473784,0.000028868073,0.00069123815,0.00031425137,0.00027008445,0.00040469068,0.96852326,0.000010074414,0.022596413,0.00040641133],"about_ca_topic_score_codex":0.00012694992,"about_ca_topic_score_gemma":0.00007065579,"teacher_disagreement_score":0.018212656,"about_ca_system_score_codex":0.0004720274,"about_ca_system_score_gemma":0.0001652639,"threshold_uncertainty_score":0.99982697},"labels":[],"label_agreement":null},{"id":"W2140663833","doi":"10.1124/mol.114.093294","title":"Complex Pharmacology of Novel Allosteric Free Fatty Acid 3 Receptor Ligands","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Allosteric regulation; Chemistry; Biochemistry; Pharmacology; Receptor; Stereochemistry; Computational biology; Biology","score_opus":0.017822756226214733,"score_gpt":0.2807837400377126,"score_spread":0.2629609838114979,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140663833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89584386,0.00046992593,0.099896856,0.00061167445,0.0016899229,0.00037455367,0.00006212149,0.000036337427,0.0010147669],"genre_scores_gemma":[0.9848385,0.00010348923,0.010208697,0.0037222682,0.0006649899,0.0000711961,0.00020624675,0.00006649683,0.000118108386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979822,0.00019296247,0.00048150925,0.0006050502,0.00020436519,0.0005339263],"domain_scores_gemma":[0.9989197,0.000028746512,0.00025373482,0.00042103702,0.00018471935,0.00019205468],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040152352,0.0003295886,0.00045075052,0.00011459033,0.00009246748,0.000012955957,0.0007069553,0.0003084724,0.0017897115],"category_scores_gemma":[0.000054774122,0.00034075466,0.00023319217,0.00017203853,0.0001905144,0.0000060028983,0.00043955192,0.00020162275,0.000026081409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002287377,0.00026443336,0.00005207153,0.00004178898,0.0002490394,0.000005279926,0.00003806642,0.00028689986,0.9822537,0.0002443807,0.015329027,0.0010066332],"study_design_scores_gemma":[0.00343173,0.00075838267,0.000047811744,0.000006071275,0.0001079814,0.000025384901,0.00001573016,0.0010731827,0.9263549,0.00005152313,0.06780727,0.00032006495],"about_ca_topic_score_codex":0.000009621095,"about_ca_topic_score_gemma":0.0000018924052,"teacher_disagreement_score":0.08968816,"about_ca_system_score_codex":0.000021767202,"about_ca_system_score_gemma":0.00007075388,"threshold_uncertainty_score":0.99990445},"labels":[],"label_agreement":null},{"id":"W2140842726","doi":"10.1124/mol.65.3.802","title":"Effects of SEA0400 on Mutant NCX1.1 Na+-Ca2+ Exchangers with Altered Ionic Regulation","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Chemistry; Mutant; Ionic bonding; Radiochemistry; Physics; Ion; Biochemistry; Gene","score_opus":0.006132274912074198,"score_gpt":0.24459859933798095,"score_spread":0.23846632442590676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140842726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737568,0.00021749992,0.023592917,0.00041883552,0.0010078292,0.0005127847,0.000005287638,0.000027042312,0.00046100692],"genre_scores_gemma":[0.9979596,0.00004516795,0.00023130458,0.0010188773,0.00033349422,0.00006513687,0.00012110124,0.000033749908,0.00019155531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989025,0.00011330534,0.00019253486,0.0003623626,0.00018468432,0.0002446079],"domain_scores_gemma":[0.9994591,0.000017320735,0.00013709556,0.00018754529,0.00011195298,0.00008699961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009970509,0.00018840111,0.0001743536,0.00011304904,0.00006359082,0.0000069152375,0.000107735854,0.00016987683,0.00006162087],"category_scores_gemma":[0.000024441635,0.00017132596,0.00008883199,0.00016614041,0.0001030104,0.0000050304748,0.00003753002,0.00009882236,0.000014913053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069303624,0.00016289832,0.000022199265,0.000052789877,0.000117002084,0.000021853952,0.000052563682,0.018562283,0.97877,0.00030200652,0.0004373246,0.00080601306],"study_design_scores_gemma":[0.003590892,0.0012705103,0.00094603637,0.000021714206,0.00006937401,0.00003000275,0.00001290687,0.00035835613,0.9906912,0.000101773156,0.0027226817,0.00018455475],"about_ca_topic_score_codex":0.0000074105515,"about_ca_topic_score_gemma":0.0000018817728,"teacher_disagreement_score":0.024202816,"about_ca_system_score_codex":0.000050811723,"about_ca_system_score_gemma":0.00008248553,"threshold_uncertainty_score":0.698647},"labels":[],"label_agreement":null},{"id":"W2141832375","doi":"10.1124/mol.107.040881","title":"Activity and Subcellular Trafficking of the Sodium-Coupled Choline Transporter CHT Is Regulated Acutely by Peroxynitrite","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Peroxynitrite; Internalization; Choline; Chemistry; Nitric oxide; Biophysics; Reactive oxygen species; Biochemistry; Cell; Cell biology; Superoxide; Biology","score_opus":0.006311725722275431,"score_gpt":0.23967340285091016,"score_spread":0.23336167712863473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141832375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950888,0.00065892376,0.0029414452,0.00045136217,0.00021754517,0.00017673385,0.0000225577,0.000053396543,0.00038923702],"genre_scores_gemma":[0.99855614,0.00006925574,0.00004809817,0.00067275896,0.00007377391,0.00000685862,0.000015881873,0.000041200932,0.00051605224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985773,0.000060233186,0.0003382764,0.00039946428,0.00025347076,0.00037123004],"domain_scores_gemma":[0.9993061,0.0000311559,0.00019632028,0.00027437165,0.000080767655,0.00011128739],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002592085,0.00023841836,0.00029383163,0.000069203634,0.000116706615,0.000012974262,0.0002025273,0.00027292853,0.00062759017],"category_scores_gemma":[0.000009664384,0.0002074503,0.00018817432,0.00022787244,0.00017098579,0.000050367013,0.000044238852,0.00039403205,0.0000023712003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002937756,0.0001409624,0.00016582306,0.000060915438,0.0001516599,0.000068076755,0.00018315845,0.000023235032,0.99454814,0.0000035365163,0.00028848505,0.004072216],"study_design_scores_gemma":[0.0023801955,0.00004069779,0.00076413195,0.000012021477,0.00020864153,0.000054242435,0.000017072167,0.0041326475,0.9859905,0.000008184835,0.006190259,0.00020141054],"about_ca_topic_score_codex":0.000058207756,"about_ca_topic_score_gemma":0.00000658341,"teacher_disagreement_score":0.0085576605,"about_ca_system_score_codex":0.000037329253,"about_ca_system_score_gemma":0.000024417539,"threshold_uncertainty_score":0.84595776},"labels":[],"label_agreement":null},{"id":"W2142186495","doi":"10.1124/mol.113.089433","title":"The Novel Arsenical Darinaparsin Is Transported by Cystine Importing Systems","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Arsenic trioxide; Glutathione; Intracellular; Cystine; Chemistry; Cysteine; Programmed cell death; Toxicity; Acute promyelocytic leukemia; In vitro; Cell; Biochemistry; Apoptosis; Cell biology; Biology; Gene; Enzyme","score_opus":0.0051326071552713895,"score_gpt":0.2495917429048816,"score_spread":0.2444591357496102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142186495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.926967,0.0044159964,0.06303141,0.0010134104,0.00088590034,0.00036500886,0.000025646752,0.000045861805,0.0032497498],"genre_scores_gemma":[0.99615777,0.00020086701,0.00020859804,0.0018562323,0.0003268628,0.000082254104,0.0001514326,0.000050296,0.00096567755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805194,0.00016955179,0.0004802294,0.0005462509,0.0002127346,0.0005392903],"domain_scores_gemma":[0.9990871,0.00004575958,0.00020900213,0.000390592,0.00011980093,0.00014776131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057886174,0.00026267933,0.00024068129,0.00002488876,0.00026075426,0.000050874773,0.00048889586,0.0002623716,0.000027586366],"category_scores_gemma":[0.00008416454,0.00021263097,0.00014339828,0.00012447673,0.00025321025,0.0000037369584,0.000096891825,0.00025680248,0.000014814745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008845605,0.00007296002,0.00013512903,0.000028266693,0.00014569944,0.000012268715,0.000017030168,0.0001425196,0.9806345,0.00025396564,0.017372776,0.001096417],"study_design_scores_gemma":[0.00091899215,0.00016509446,0.000028635523,0.0000046326654,0.00007710364,0.00007542109,0.00001890906,0.0016825276,0.65655935,0.00002735647,0.3402386,0.00020336022],"about_ca_topic_score_codex":0.000019528248,"about_ca_topic_score_gemma":0.000001792036,"teacher_disagreement_score":0.32407513,"about_ca_system_score_codex":0.000021982725,"about_ca_system_score_gemma":0.00011118905,"threshold_uncertainty_score":0.8670839},"labels":[],"label_agreement":null},{"id":"W2142821504","doi":"10.1124/mol.104.004416","title":"Biochemical and Proteomics Approaches to Characterize Topoisomerase IIα Cysteines and DNA as Targets Responsible for Cisplatin-Induced Inhibition of Topoisomerase IIα","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Topoisomerase; Cisplatin; Cysteine; Etoposide; Chemistry; Kinetoplast; Dithiothreitol; Biochemistry; DNA; Enzyme; Biology","score_opus":0.040245421411999355,"score_gpt":0.27991173409096376,"score_spread":0.2396663126789644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142821504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98959106,0.00066325354,0.006091604,0.0021353161,0.00016308282,0.0012287892,0.000082953935,0.000012585028,0.000031351126],"genre_scores_gemma":[0.99164665,0.00010417879,0.0056349775,0.0018939628,0.00014332408,0.00034984917,0.00014521746,0.000039267976,0.00004255727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875396,0.00005877533,0.00028405056,0.0005028856,0.00009435259,0.00030595448],"domain_scores_gemma":[0.99942315,0.000015701817,0.00011658812,0.00018656647,0.00007958059,0.00017840366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019262718,0.00023282167,0.000279358,0.000103981525,0.000077229044,0.000018601419,0.00009255276,0.00021209003,0.000008320465],"category_scores_gemma":[0.000041012976,0.00024339798,0.00007775141,0.00009934473,0.00008330331,0.000007777304,0.00011891073,0.00009117303,0.0000011491793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012656935,0.00012430151,0.0000056162903,0.00008975713,0.000099146426,0.000014402595,0.00013150575,0.000016349046,0.99576473,0.0013182467,0.000044364482,0.0011258579],"study_design_scores_gemma":[0.003158476,0.0013674989,0.000043748998,0.000018891033,0.0000820095,0.000059466132,0.00004018497,0.000035696827,0.99149895,0.0013945864,0.0020345082,0.0002659746],"about_ca_topic_score_codex":0.000021985188,"about_ca_topic_score_gemma":0.000006568211,"teacher_disagreement_score":0.0042658,"about_ca_system_score_codex":0.00002647686,"about_ca_system_score_gemma":0.0001361829,"threshold_uncertainty_score":0.99254817},"labels":[],"label_agreement":null},{"id":"W2142945288","doi":"10.1124/mol.104.005769","title":"Expression of the Retinoic Acid-Metabolizing Enzyme CYP26A1 Limits Programmed Cell Death","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Retinoic acid; Apoptosis; Programmed cell death; Carcinogenesis; Biology; Enzyme; Cell culture; Cancer cell; Biochemistry; Chemistry; Cancer research; Cell biology; Cancer; Genetics","score_opus":0.009112317090034254,"score_gpt":0.2642142233002097,"score_spread":0.2551019062101755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142945288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845955,0.007835127,0.0024504524,0.0003182522,0.0003829632,0.0004389474,0.0000069660387,0.000027387905,0.003944451],"genre_scores_gemma":[0.99481195,0.00028473107,0.0025620684,0.0011796621,0.00037773073,0.000067829365,0.000032303633,0.00004856888,0.0006351634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813366,0.00029157323,0.00037233255,0.00049029686,0.00024296765,0.00046917188],"domain_scores_gemma":[0.9990117,0.000014841037,0.00024610833,0.00047135196,0.00014433925,0.0001116536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002437515,0.00026857972,0.00024855352,0.000051486026,0.0001245198,0.00001638583,0.0006567368,0.00028278455,0.00007961618],"category_scores_gemma":[0.00006215621,0.00020990493,0.00022841986,0.00018548417,0.00017561551,0.000006915727,0.00029109578,0.00025792274,0.000014076771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082542334,0.00016414886,0.0005710182,0.00006426786,0.00003636438,0.000009232495,0.000056786263,0.00029991078,0.9948705,0.000047459245,0.00190488,0.0018929116],"study_design_scores_gemma":[0.0010389166,0.0001258942,0.000122456,0.000014358172,0.00009191396,0.000026628422,0.000024954437,0.00007398114,0.9284477,0.000034329172,0.069781676,0.00021715518],"about_ca_topic_score_codex":0.0000032163964,"about_ca_topic_score_gemma":0.0000012822876,"teacher_disagreement_score":0.06787679,"about_ca_system_score_codex":0.000025409663,"about_ca_system_score_gemma":0.00017478465,"threshold_uncertainty_score":0.85596746},"labels":[],"label_agreement":null},{"id":"W2143329135","doi":"10.1124/mol.106.027946","title":"Short Polybasic Peptide Sequences Are Potent Inhibitors of PC5/6 and PC7: Use of Positional Scanning-Synthetic Peptide Combinatorial Libraries as a Tool for the Optimization of Inhibitory Sequences","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute on Drug Abuse","keywords":"Furin; Peptide; Arginine; Chemistry; Peptide synthesis; Cyclic peptide; Enzyme; Stereochemistry; Biochemistry; Proprotein convertase; Amino acid","score_opus":0.015162437246254845,"score_gpt":0.26911542818816525,"score_spread":0.25395299094191043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143329135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937644,0.00054848695,0.0030274454,0.0016579344,0.00015912091,0.0005904468,0.000114003364,0.000023489123,0.00011470089],"genre_scores_gemma":[0.9973593,0.000040442854,0.0017878019,0.00038305108,0.00016697227,0.00006981077,0.0000989792,0.000021025195,0.00007263401],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838704,0.00015277634,0.0006232764,0.000277945,0.0003496394,0.00020934269],"domain_scores_gemma":[0.9987756,0.00029000145,0.00036994426,0.00014780428,0.00034895213,0.000067724155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022613393,0.00019332721,0.00046868648,0.0002476276,0.00010416564,0.000019074934,0.00009575189,0.00012081983,0.00008508043],"category_scores_gemma":[0.00010506791,0.00015655691,0.00024189899,0.00028044105,0.0008239281,0.00018092354,0.0000583471,0.00013338042,5.1100113e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006629776,0.00047040853,0.007410982,0.00028588294,0.00041357745,0.00006696201,0.00012874957,0.026651703,0.95857257,0.002636592,0.0025185123,0.00018107149],"study_design_scores_gemma":[0.0019819266,0.0005217066,0.003321207,0.00041163925,0.0008929118,0.00008367602,0.00026679525,0.005924653,0.9854365,0.0007905157,0.00017504927,0.00019343916],"about_ca_topic_score_codex":0.00015999326,"about_ca_topic_score_gemma":0.000003867118,"teacher_disagreement_score":0.0268639,"about_ca_system_score_codex":0.00004146539,"about_ca_system_score_gemma":0.0002142792,"threshold_uncertainty_score":0.6384205},"labels":[],"label_agreement":null},{"id":"W2144190398","doi":"10.1124/mol.63.3.617","title":"Erythromycin, Roxithromycin, and Clarithromycin: Use of Slow-Binding Kinetics to Compare Their in Vitro Interaction with a Bacterial Ribosomal Complex Active in Peptide Bond Formation","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Roxithromycin; Clarithromycin; In vitro; Erythromycin; Kinetics; Ribosomal RNA; Chemistry; 23S ribosomal RNA; Microbiology; Peptide; Biochemistry; Biology; Antibiotics; Ribosome","score_opus":0.025472391621851186,"score_gpt":0.27091416736963697,"score_spread":0.24544177574778578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144190398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931729,0.00006255494,0.0055232486,0.00015796561,0.00013710279,0.00074704975,0.000050993764,0.000007806047,0.0001404016],"genre_scores_gemma":[0.9917808,0.00003134577,0.007514777,0.00035298284,0.000034049674,0.00009072049,0.00015088658,0.000032606255,0.000011826808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839264,0.00036000926,0.00038362795,0.0004040009,0.00011318507,0.00034651664],"domain_scores_gemma":[0.99941576,0.000043704484,0.00017227362,0.00018586955,0.00008498723,0.00009740446],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016923006,0.00025788805,0.0003760953,0.0002150753,0.000041107513,0.00002608507,0.0001146645,0.00013299516,0.000040834057],"category_scores_gemma":[0.000043258267,0.00024880614,0.000059851045,0.00020319513,0.00007669642,0.00003321996,0.000083517334,0.00016635451,0.0000020399539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015504098,0.00017485498,0.00027261095,0.000034511562,0.00006813138,0.000023819344,0.00025960463,0.00059775036,0.99598974,0.000042316886,0.00012846908,0.00085780694],"study_design_scores_gemma":[0.002067544,0.000623673,0.0018737942,0.00004568048,0.00003417206,0.00010280071,0.0003580859,0.00014209963,0.989461,0.000030687024,0.004999699,0.00026073787],"about_ca_topic_score_codex":0.000060570546,"about_ca_topic_score_gemma":0.00017939428,"teacher_disagreement_score":0.006528688,"about_ca_system_score_codex":0.000066139306,"about_ca_system_score_gemma":0.000045211436,"threshold_uncertainty_score":0.9999964},"labels":[],"label_agreement":null},{"id":"W2144399446","doi":"10.1124/mol.105.014449","title":"Nitric Oxide Inhibits Endothelin-1-Induced Cardiomyocyte Hypertrophy through cGMP-mediated Suppression of Extracellular-Signal Regulated Kinase Phosphorylation","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Signal transduction; MAPK/ERK pathway; Phosphorylation; Biology; Endothelin 1; Activator (genetics); Kinase; Nitric oxide synthase; Molecular biology; Cell biology; Nitric oxide; Endocrinology; Internal medicine; Chemistry; Biochemistry; Receptor; Medicine","score_opus":0.014076988689345038,"score_gpt":0.2745835727802358,"score_spread":0.2605065840908908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144399446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893569,0.0048901476,0.0027957333,0.00052754075,0.0002603091,0.0010719727,0.00002643229,0.00016945232,0.0009015614],"genre_scores_gemma":[0.99490553,0.0002168771,0.0024577975,0.0013091506,0.00029883801,0.00007395086,0.00013498211,0.00009415179,0.0005087305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99711704,0.00041402594,0.00073657325,0.00058075076,0.00053194346,0.0006196476],"domain_scores_gemma":[0.99850667,0.00023067804,0.000311247,0.0004067113,0.00028830272,0.00025636607],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037042,0.0004079839,0.0007901313,0.00034601282,0.00009180549,0.000010176112,0.00018302983,0.00037393224,0.000737076],"category_scores_gemma":[0.000121999896,0.0003786494,0.0003311176,0.00059033104,0.000121406,0.00015194718,0.00009523994,0.0005236229,0.000229945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013756284,0.0004733764,0.00023964579,0.0001195102,0.0003210637,0.00074221264,0.00013939435,0.0006966024,0.98855,0.000026539738,0.0008829854,0.0064330366],"study_design_scores_gemma":[0.008124534,0.00036159513,0.0004817307,0.00007291959,0.0006718982,0.00022248155,0.000022438793,0.0051357807,0.97764415,0.000047410907,0.006899548,0.00031553715],"about_ca_topic_score_codex":0.00007015556,"about_ca_topic_score_gemma":7.29275e-7,"teacher_disagreement_score":0.01090588,"about_ca_system_score_codex":0.00017424373,"about_ca_system_score_gemma":0.00019916866,"threshold_uncertainty_score":0.99986655},"labels":[],"label_agreement":null},{"id":"W2144799280","doi":"10.1124/mol.113.088880","title":"Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Functional selectivity; Receptor; Signal transduction; Effector; Ligand (biochemistry); Drug discovery; Biology; Computational biology; G protein-coupled receptor; Chemistry; Cell biology; Biochemistry","score_opus":0.044760056363428155,"score_gpt":0.3180297258884246,"score_spread":0.27326966952499643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144799280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7503642,0.0006288273,0.24467368,0.0014614151,0.00052003283,0.00215407,0.000102948565,0.000019684552,0.00007512588],"genre_scores_gemma":[0.9727203,0.00026035783,0.021621056,0.00081893994,0.0003035383,0.0032761628,0.0005488016,0.000051208186,0.00039958977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983631,0.00007070531,0.000646991,0.000520129,0.00006697726,0.0003321196],"domain_scores_gemma":[0.9985783,0.0001265896,0.00036581917,0.00032919328,0.0004793444,0.0001207402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004781905,0.0001992531,0.0002993133,0.00007297345,0.000111552974,0.000023260778,0.00030586802,0.00021079773,0.00010411321],"category_scores_gemma":[0.00016693716,0.00019582854,0.0002865925,0.00009698044,0.00008532713,0.0000077716895,0.00006555103,0.00007707226,0.000012316162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013347136,0.00013410095,0.00011422522,0.000047500533,0.00013342321,1.0513188e-7,0.000016258624,0.00023206533,0.9755237,0.0011013552,0.019262685,0.0033010761],"study_design_scores_gemma":[0.0012299878,0.00043920169,0.000058495178,0.000008398688,0.000088186505,0.0000023698508,0.000030077133,0.00050144485,0.9261895,0.0008541436,0.07039043,0.00020777035],"about_ca_topic_score_codex":0.000013847621,"about_ca_topic_score_gemma":0.0000021702058,"teacher_disagreement_score":0.22305262,"about_ca_system_score_codex":0.000014948063,"about_ca_system_score_gemma":0.00012528818,"threshold_uncertainty_score":0.7985656},"labels":[],"label_agreement":null},{"id":"W2144957732","doi":"10.1124/mol.60.5.1143","title":"Acquisition of Human Concentrative Nucleoside Transporter 2 (hCNT2) Activity by Gene Transfer Confers Sensitivity to Fluoropyrimidine Nucleosides in Drug-Resistant Leukemia Cells","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research","funders":"","keywords":"Uridine; Nucleoside; Cladribine; Deoxyadenosine; Thymidine; Nucleoside transporter; Chemistry; Deoxyuridine; Biochemistry; Cytarabine; Adenosine; Nucleoside analogue; Stereochemistry; In vitro; Leukemia; Biology; Transporter; DNA; Gene; RNA","score_opus":0.009042938658610876,"score_gpt":0.27335204993894285,"score_spread":0.26430911128033197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144957732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99374974,0.000103744394,0.0015188919,0.0022811503,0.00010427417,0.0011995772,0.000087327695,0.000053288797,0.0009019849],"genre_scores_gemma":[0.9975261,0.00008119472,0.00036756168,0.0013582269,0.000033947443,0.00006773577,0.0001269599,0.00004611048,0.000392142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978884,0.00030390194,0.00045872634,0.0005337318,0.00029396525,0.00052131637],"domain_scores_gemma":[0.9992925,0.00006124435,0.0000692601,0.0001855927,0.00011408418,0.00027731844],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026742075,0.00035276622,0.0007109151,0.00020762031,0.00007380774,0.000008778198,0.00007926621,0.00014065098,0.000503238],"category_scores_gemma":[0.0000034970008,0.00035022586,0.0001660401,0.00031047265,0.00016799118,0.00008762131,0.000020289415,0.00023901559,0.000025369478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017888158,0.0007744941,0.0017767337,0.000057023473,0.00033346805,0.0028206746,0.0016404014,0.000075538395,0.98788047,0.00007108557,0.0022310496,0.00055026903],"study_design_scores_gemma":[0.005833864,0.00026606003,0.007767867,0.00005669696,0.00037704498,0.000030335115,0.00011478608,0.00013405917,0.98357546,0.000012471424,0.0015401932,0.00029116208],"about_ca_topic_score_codex":0.00035095864,"about_ca_topic_score_gemma":0.00017664742,"teacher_disagreement_score":0.005991133,"about_ca_system_score_codex":0.0004906759,"about_ca_system_score_gemma":0.0001781404,"threshold_uncertainty_score":0.999895},"labels":[],"label_agreement":null},{"id":"W2145082934","doi":"10.1124/mol.105.012187","title":"Uridine Binding and Transportability Determinants of Human Concentrative Nucleoside Transporters","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoside; Pyrimidine; Nucleoside analogue; Chemistry; Transporter; Xenopus; Biochemistry; Uridine; Cytidine; Biology; Biophysics; RNA; Gene; Enzyme","score_opus":0.010109125301892612,"score_gpt":0.29651081224187414,"score_spread":0.2864016869399815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145082934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972654,0.0016357146,0.00047760768,0.00014248944,0.00006175037,0.00019791747,0.000027330008,0.000010359809,0.00018143622],"genre_scores_gemma":[0.99900013,0.00009727267,0.00030620286,0.0003547242,0.00010779338,0.000014040522,0.000049317074,0.000020094856,0.000050440773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989522,0.000070330185,0.0003180219,0.0003289498,0.00008266498,0.0002478329],"domain_scores_gemma":[0.99960977,0.00000984928,0.0001093114,0.00012808025,0.000046274385,0.00009669854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013727706,0.00016486665,0.00023600187,0.000041538435,0.00006184588,0.000004002981,0.00012198743,0.00011615464,0.00012900528],"category_scores_gemma":[0.0000051898005,0.0001696063,0.000087791275,0.00006241193,0.00020220957,0.0000059308527,0.000022162769,0.000090182264,0.0000012799903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000893272,0.00008351811,0.018775139,0.000029942768,0.00006954578,0.000035846468,0.00014092482,0.000090176654,0.97960645,0.000030643616,0.0005331039,0.000515406],"study_design_scores_gemma":[0.0012715589,0.00027557297,0.0037495585,0.000008604631,0.00010053426,0.000022665203,0.000041943415,0.0000784195,0.9917007,0.000010542953,0.0025650423,0.00017481946],"about_ca_topic_score_codex":0.000014108377,"about_ca_topic_score_gemma":0.000010615192,"teacher_disagreement_score":0.01502558,"about_ca_system_score_codex":0.000009202548,"about_ca_system_score_gemma":0.000036439353,"threshold_uncertainty_score":0.6916344},"labels":[],"label_agreement":null},{"id":"W2145416895","doi":"10.1124/mol.62.2.210","title":"The Ca2+ Channel Antagonists Mibefradil and Pimozide Inhibit Cell Growth via Different Cytotoxic Mechanisms","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Mibefradil; Pimozide; Cytotoxic T cell; Transfection; Channel blocker; Cell growth; Pharmacology; Chemistry; Molecular biology; Biology; Endocrinology; Haloperidol; Biochemistry; In vitro; Gene; Receptor; Antagonist; Dopamine; Calcium","score_opus":0.007559890298541256,"score_gpt":0.21767775935210626,"score_spread":0.210117869053565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145416895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95005435,0.0024971808,0.04083211,0.002933085,0.0020754577,0.0005917898,0.000016240478,0.00005154276,0.00094822363],"genre_scores_gemma":[0.9950665,0.00084962713,0.00007240858,0.002050064,0.00035592655,0.0000874953,0.00005869327,0.000039247334,0.0014200219],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858975,0.00017927885,0.00023579234,0.00044089995,0.00015475559,0.00039949492],"domain_scores_gemma":[0.9994298,0.000025898855,0.00010254172,0.0002035164,0.00008219966,0.0001560499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013505427,0.00025118166,0.00016517249,0.000060375136,0.00032501205,0.00003913864,0.0001709041,0.00020171821,0.000088968234],"category_scores_gemma":[0.00002035325,0.00020060815,0.00009998478,0.00009258374,0.00014438505,0.0000051995653,0.00014509266,0.00015858354,0.000029856781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006850526,0.000096265656,0.000021748492,0.00001569429,0.000053588312,0.000021631426,0.000047004392,0.000049036873,0.9922329,0.00020806034,0.006543934,0.00064159284],"study_design_scores_gemma":[0.001281052,0.0003298151,0.00012377152,0.0000022230515,0.000045999892,0.00007359884,0.000026795922,0.0058147702,0.97922593,0.0006304634,0.012202668,0.00024293033],"about_ca_topic_score_codex":0.0000066745993,"about_ca_topic_score_gemma":0.0000043258974,"teacher_disagreement_score":0.045012146,"about_ca_system_score_codex":0.000026938818,"about_ca_system_score_gemma":0.000012286654,"threshold_uncertainty_score":0.8180563},"labels":[],"label_agreement":null},{"id":"W2145581228","doi":"10.1124/mol.64.3.670","title":"The Metabolites of the Cardioprotective Drug Dexrazoxane Do Not Protect Myocytes from Doxorubicin-Induced Cytotoxicity","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Dexrazoxane; Doxorubicin; Calcein; Chemistry; Pharmacology; Myocyte; Cytotoxicity; Biochemistry; Calcium; Anthracycline; Endocrinology; Internal medicine; Medicine; In vitro; Chemotherapy","score_opus":0.010949932851110573,"score_gpt":0.26759116872218836,"score_spread":0.2566412358710778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145581228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99155635,0.0015081206,0.0004884797,0.0016705658,0.0005100907,0.0025431635,0.000024350884,0.000052514722,0.0016463415],"genre_scores_gemma":[0.9971112,0.00007783053,0.00024273616,0.0018942987,0.00017366368,0.00031803743,0.0000044016156,0.000043474458,0.00013434765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99733406,0.0009520148,0.0003994529,0.0004376697,0.00045979774,0.00041699377],"domain_scores_gemma":[0.9985292,0.0002717552,0.0002449192,0.00059386,0.0002448123,0.000115470335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000734302,0.00028838936,0.0005732387,0.00007036668,0.00029647237,0.000027131504,0.00028979787,0.00018962608,0.000081822145],"category_scores_gemma":[0.00034107346,0.00018274112,0.0004836752,0.00043009856,0.00028566617,0.000051098767,0.000074208605,0.00065698073,0.0000107087835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029317412,0.00008947469,0.00014855531,0.000023631092,0.00080787425,0.000025146976,0.0004233052,0.000034373377,0.99582726,0.00071141956,0.00010812207,0.0015076826],"study_design_scores_gemma":[0.0025730438,0.00010404376,0.0016487614,0.00003039333,0.00050936994,0.000054996915,0.00018036242,0.000033188346,0.9898115,0.0009563543,0.0039191954,0.00017879336],"about_ca_topic_score_codex":0.00019267545,"about_ca_topic_score_gemma":0.000009399645,"teacher_disagreement_score":0.0060157436,"about_ca_system_score_codex":0.00014852053,"about_ca_system_score_gemma":0.00026751278,"threshold_uncertainty_score":0.74519664},"labels":[],"label_agreement":null},{"id":"W2145835097","doi":"10.1124/mol.113.091314","title":"A Novel Pathway for Arsenic Elimination: Human Multidrug Resistance Protein 4 (MRP4/ABCC4) Mediates Cellular Export of Dimethylarsinic Acid (DMAV) and the Diglutathione Conjugate of Monomethylarsonous Acid (MMAIII)","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Arsenic; Multidrug resistance-associated protein 2; Chemistry; Biochemistry; ATP-binding cassette transporter; Transporter; Organic chemistry","score_opus":0.007823066645091555,"score_gpt":0.23807641984671898,"score_spread":0.23025335320162743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145835097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9416721,0.00046976237,0.054207165,0.001139052,0.00012655283,0.0016838259,0.000029898973,0.000025074647,0.00064659887],"genre_scores_gemma":[0.9950712,0.000020628911,0.003836156,0.00027073576,0.000028316688,0.00035697912,0.000036456757,0.0000256759,0.00035385942],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981583,0.00031418167,0.000574724,0.0004028148,0.0002782042,0.00027180943],"domain_scores_gemma":[0.9988782,0.00019251627,0.0005186869,0.0002560941,0.00006559089,0.000088954475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013332241,0.0002056854,0.00039240607,0.000075735144,0.00016222072,0.000010011282,0.00026953957,0.00011223175,0.00015600062],"category_scores_gemma":[0.00017827984,0.00017647103,0.00013302577,0.00018183082,0.00071915437,0.0001230318,0.00015481992,0.00014700185,0.0000063208477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015602738,0.00014662689,0.000030984946,0.000057699937,0.000048345115,0.000002804591,0.0011731215,0.000030996245,0.9895658,0.0050772466,0.000034512414,0.0036758254],"study_design_scores_gemma":[0.0049299975,0.00017931635,0.0006718602,0.00001740986,0.00010192127,0.0000030230394,0.0001375383,0.0027502603,0.9870518,0.0016955736,0.0022808595,0.00018046785],"about_ca_topic_score_codex":0.000028854101,"about_ca_topic_score_gemma":0.00003795822,"teacher_disagreement_score":0.053399123,"about_ca_system_score_codex":0.00006082586,"about_ca_system_score_gemma":0.000028841485,"threshold_uncertainty_score":0.719628},"labels":[],"label_agreement":null},{"id":"W2147012374","doi":"10.1124/mol.111.071332","title":"Ligand-Dependent TrkA Activity in Brain Differentially Affects Spatial Learning and Long-Term Memory","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Tropomyosin receptor kinase A; Low-affinity nerve growth factor receptor; Nerve growth factor; Neurotrophin; Hippocampus; Neuroscience; Neurotrophic factors; Brain-derived neurotrophic factor; Biology; Receptor; Endocrinology; Psychology; Chemistry; Internal medicine; Medicine; Biochemistry","score_opus":0.022646837755020438,"score_gpt":0.33076886540276024,"score_spread":0.30812202764773977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147012374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960905,0.0015729521,0.0004338204,0.00025509953,0.00012619319,0.00069857755,0.0000030104152,0.000046190085,0.0007736593],"genre_scores_gemma":[0.9993263,0.00013203912,0.000021465015,0.00024200282,0.00006171201,0.00007948306,0.000018535986,0.000030598112,0.00008789089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984821,0.00035563743,0.0001194877,0.00037749574,0.0002245036,0.00044079506],"domain_scores_gemma":[0.9994044,0.000062772015,0.00005352611,0.000109545545,0.000029226805,0.00034056598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014652204,0.00019447855,0.00031281848,0.00017770918,0.000060880528,0.000011074342,0.00006864505,0.00010761263,0.00044517027],"category_scores_gemma":[0.00003038359,0.0001784283,0.00007649282,0.00008518843,0.000110588175,0.00005368129,0.00013195588,0.00037731117,0.00003345755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025301287,0.0016844709,0.28309548,0.0001424726,0.003074426,0.014810809,0.00029051793,0.0000017428679,0.67414194,0.000006833598,0.000052798405,0.02016837],"study_design_scores_gemma":[0.007238416,0.00080597796,0.47248033,0.000028106637,0.0004459856,0.0000867351,0.000008410008,0.00015662046,0.51858217,0.000020099124,0.000004245586,0.00014289057],"about_ca_topic_score_codex":0.00010298298,"about_ca_topic_score_gemma":0.00006217634,"teacher_disagreement_score":0.18938486,"about_ca_system_score_codex":0.00007013486,"about_ca_system_score_gemma":0.00012387901,"threshold_uncertainty_score":0.72760946},"labels":[],"label_agreement":null},{"id":"W2147198454","doi":"10.1124/mol.64.3.587","title":"Recruitment of RGS2 and RGS4 to the Plasma Membrane by G Proteins and Receptors Reflects Functional Interactions","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"RGS2; Regulator of G protein signaling; G protein; Cell biology; GTPase-activating protein; G protein-coupled receptor; Gq alpha subunit; Biology; Vesicle-associated membrane protein 8; GTP-binding protein regulators; Receptor; Signal transduction; Membrane protein; Biochemistry; Membrane","score_opus":0.02367105375627194,"score_gpt":0.29412325326497174,"score_spread":0.2704521995086998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147198454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882009,0.00092592,0.007987628,0.0009199746,0.00057126395,0.0007780014,0.000012451831,0.000007332863,0.0005965434],"genre_scores_gemma":[0.9962786,0.00020954851,0.0013823267,0.0010689865,0.00006321204,0.00026545188,0.000031361855,0.000020356205,0.00068015704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990334,0.00020075738,0.00017605143,0.00030693563,0.000095930416,0.00018691283],"domain_scores_gemma":[0.99962646,0.000020445814,0.00006802849,0.00012286693,0.000060230923,0.00010198785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023087738,0.00013660965,0.00013338566,0.00004690975,0.000103602,0.000012405194,0.00007465979,0.00008135825,0.00027623336],"category_scores_gemma":[0.000047315196,0.000111627625,0.000042347892,0.00009273932,0.00006201837,0.0000036212143,0.000067368404,0.000108356944,0.000003697343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001433829,0.00005131205,0.000016638169,0.0000108156155,0.00010454778,0.000001958851,0.000057863443,0.00010174914,0.9922907,0.00043819618,0.005410555,0.0013722765],"study_design_scores_gemma":[0.0005689912,0.00028010487,0.000005574183,0.0000042212328,0.000031689113,0.00003093187,0.00004559496,0.000031044343,0.7589292,0.00003454658,0.23994881,0.000089283116],"about_ca_topic_score_codex":0.000008250376,"about_ca_topic_score_gemma":0.000008050381,"teacher_disagreement_score":0.23453826,"about_ca_system_score_codex":0.000013196719,"about_ca_system_score_gemma":0.00003866106,"threshold_uncertainty_score":0.45520425},"labels":[],"label_agreement":null},{"id":"W2147518502","doi":"10.1124/mol.111.072587","title":"Identification of Cysteines Involved in the Effects of Methanethiosulfonate Reagents on Human Equilibrative Nucleoside Transporter 1","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Cysteine; Nucleoside; Reagent; Transmembrane domain; Biochemistry; Mutant; Stereochemistry; Membrane; Gene; Organic chemistry; Enzyme","score_opus":0.025836666395585746,"score_gpt":0.3044628004400956,"score_spread":0.27862613404450987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147518502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99729955,0.0010054681,0.00072579674,0.000041737767,0.00012232062,0.000344236,0.000005812762,0.0000040459604,0.00045101382],"genre_scores_gemma":[0.9992282,0.000052992782,0.000071899456,0.00046996205,0.00003701936,0.000048515936,0.000040157065,0.000015730035,0.000035545265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879724,0.00034201422,0.00036516043,0.00022916652,0.00011822341,0.00014818377],"domain_scores_gemma":[0.99946326,0.000037756825,0.00020300584,0.00021641508,0.000055630462,0.000023924722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028136274,0.00012845887,0.00018214417,0.00008259562,0.000021208578,0.0000020257594,0.00028261932,0.000114550305,0.000026716625],"category_scores_gemma":[0.000027790475,0.00010324797,0.00009149249,0.00012579713,0.00010776417,0.000004348091,0.000031428088,0.000099845354,0.0000014872336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001687759,0.00022454404,0.0006464077,0.00008858756,0.000103254766,0.00004827282,0.0008109113,0.000038695456,0.99670446,0.0004366749,0.00068022765,0.000049194074],"study_design_scores_gemma":[0.001002412,0.0005664443,0.0039910185,0.000019117047,0.00008275815,0.0000026406574,0.00006337066,0.00001851296,0.99375695,0.0002787634,0.00012518556,0.000092821225],"about_ca_topic_score_codex":0.000035573794,"about_ca_topic_score_gemma":0.000004123261,"teacher_disagreement_score":0.0033446108,"about_ca_system_score_codex":0.000004276132,"about_ca_system_score_gemma":0.00002046202,"threshold_uncertainty_score":0.421033},"labels":[],"label_agreement":null},{"id":"W2147812298","doi":"10.1124/mol.64.3.533","title":"Cyclic Nucleotide Phosphodiesterase Activity, Expression, and Targeting in Cells of the Cardiovascular System","year":2003,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":320,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; Queen's University","funders":"","keywords":"Nucleotide; Cyclic nucleotide phosphodiesterase; Cell biology; Effector; Phosphodiesterase; Cyclic nucleotide; Vascular smooth muscle; Biology; Transcription factor; Cell; Motility; Biochemistry; Chemistry; Smooth muscle; Endocrinology; Enzyme; Gene","score_opus":0.011969376936291227,"score_gpt":0.2701154471579879,"score_spread":0.25814607022169667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147812298","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02980356,0.96749735,0.00029159727,0.000008868107,0.0012208979,0.0009573043,0.000025453232,0.000012137961,0.00018282367],"genre_scores_gemma":[0.04704212,0.9521856,0.00012426008,0.000110146204,0.00010493897,0.00016307042,0.000044262684,0.00008069875,0.00014490444],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99716586,0.0011424309,0.0005396985,0.0006330135,0.0001959202,0.0003230809],"domain_scores_gemma":[0.99892056,0.000031845328,0.00038942765,0.00051243335,0.000060416878,0.000085337495],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044510642,0.0004235534,0.0010796415,0.00010970639,0.000091754104,0.000014014471,0.0002774466,0.000454614,0.000012666882],"category_scores_gemma":[0.000025571913,0.00031704182,0.0006824142,0.00023255697,0.00016184135,0.0000054448847,0.00033186542,0.00031707372,0.0000035695089],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007003613,0.00019055705,0.00005260133,0.014264007,0.0011758985,0.0000984702,0.00005672412,0.0005903068,0.9179206,0.000025162231,0.0040292647,0.061526407],"study_design_scores_gemma":[0.0006190521,0.000036268215,0.000008816558,0.0008969653,0.00056424545,0.00005599403,0.000014303367,0.000013136697,0.2902685,0.0000014466933,0.707234,0.00028725376],"about_ca_topic_score_codex":0.000017623273,"about_ca_topic_score_gemma":0.0000018074902,"teacher_disagreement_score":0.70320475,"about_ca_system_score_codex":0.0000713062,"about_ca_system_score_gemma":0.00014943613,"threshold_uncertainty_score":0.9999282},"labels":[],"label_agreement":null},{"id":"W2147885760","doi":"10.1124/mol.106.029926","title":"Modulating the Folding of P-Glycoprotein and Cystic Fibrosis Transmembrane Conductance Regulator Truncation Mutants with Pharmacological Chaperones","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs","funders":"Cystic Fibrosis Foundation Therapeutics; Cystic Fibrosis Foundation","keywords":"Cystic fibrosis transmembrane conductance regulator; Mutant; ATP-binding cassette transporter; Chaperone (clinical); Protein folding; Cell biology; Cyclic nucleotide-binding domain; Transmembrane protein; Transmembrane domain; Chemistry; Biology; Biophysics; Biochemistry; Nucleotide; Transporter; Amino acid; Gene; Receptor","score_opus":0.010112586384421297,"score_gpt":0.2897327389848516,"score_spread":0.27962015260043027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147885760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901754,0.0025016197,0.0043096277,0.0015656586,0.00006798062,0.0011588088,0.000014588963,0.00004825066,0.0001580527],"genre_scores_gemma":[0.992447,0.000042825242,0.0069306255,0.00021936731,0.000095587035,0.00015754679,0.000015232467,0.00002974044,0.00006204523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983282,0.00018634151,0.0003449274,0.00038044224,0.00037164247,0.0003884213],"domain_scores_gemma":[0.9992025,0.00024942975,0.00014830934,0.00015678002,0.00014192071,0.00010104471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027069694,0.00020215548,0.00038331313,0.00009529929,0.00012950641,0.000013650665,0.00012913371,0.00007784715,0.00018343025],"category_scores_gemma":[0.00006397297,0.00013335935,0.00005760536,0.00033297067,0.0005163277,0.000091655864,0.000042746393,0.00023490655,0.0000022521472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011627948,0.00012586062,0.0005099748,0.00019870876,0.000106939115,0.000108738794,0.00007051878,0.00097237446,0.99367374,0.00031729374,0.00005460218,0.0026984287],"study_design_scores_gemma":[0.0038303153,0.00078989065,0.0119199,0.00009223293,0.00032799868,0.00027191802,0.000055562403,0.0109525705,0.97094804,0.00028382783,0.00036917135,0.00015854309],"about_ca_topic_score_codex":0.000045896377,"about_ca_topic_score_gemma":0.000005140876,"teacher_disagreement_score":0.022725696,"about_ca_system_score_codex":0.000055601333,"about_ca_system_score_gemma":0.00007879568,"threshold_uncertainty_score":0.54382366},"labels":[],"label_agreement":null},{"id":"W2148253816","doi":"10.1124/mol.106.024778","title":"Structure-Based Identification of Novel Human γ-Glutamylcysteine Synthetase Inhibitors","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital","funders":"National Cancer Institute","keywords":"Identification (biology); Computational biology; Biology; Biochemistry; Chemistry","score_opus":0.0074972784129966035,"score_gpt":0.28955047879696894,"score_spread":0.28205320038397236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148253816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94791675,0.000719351,0.050195754,0.00007718066,0.0005370589,0.000259812,0.000066731795,0.000016227334,0.00021111366],"genre_scores_gemma":[0.9978321,0.00000789514,0.00085127243,0.00060832367,0.0002794042,0.000011034925,0.00023576459,0.000033930322,0.00014023813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861,0.00005692723,0.00047931308,0.00036897804,0.00016402279,0.00032076795],"domain_scores_gemma":[0.999175,0.000011424346,0.00025064705,0.00031904667,0.0001325925,0.000111298694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003712446,0.00019280077,0.0002135915,0.00013051768,0.000065367516,0.0000070097817,0.00023637815,0.00019793754,0.00008712108],"category_scores_gemma":[0.00003539295,0.00019783374,0.00013619965,0.00015103832,0.00016637676,0.000003583981,0.00007724836,0.00011169563,0.0000028200072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008515586,0.0001703698,0.00012442512,0.000025660971,0.00007466371,0.000013909128,0.000014279717,0.00076481275,0.9969393,0.00035302076,0.00075246743,0.0006819399],"study_design_scores_gemma":[0.0016420269,0.0001293181,0.0006840551,0.000004195204,0.00009820996,0.000014383773,0.000013309234,0.00012392708,0.98633415,0.000024519999,0.0107422145,0.0001896856],"about_ca_topic_score_codex":0.000015877184,"about_ca_topic_score_gemma":0.000009420178,"teacher_disagreement_score":0.049915366,"about_ca_system_score_codex":0.000015549422,"about_ca_system_score_gemma":0.000058308386,"threshold_uncertainty_score":0.80674255},"labels":[],"label_agreement":null},{"id":"W2148317422","doi":"10.1124/mol.108.049759","title":"Access and Binding of Local Anesthetics in the Closed Sodium Channel","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Binding site; Sodium channel; Crystallography; Biophysics; Sodium; Biochemistry; Biology","score_opus":0.023375585733070952,"score_gpt":0.2932827317990307,"score_spread":0.2699071460659597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148317422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99245054,0.00023400043,0.006040791,0.00052827783,0.00027648604,0.00017335285,0.0000029250486,0.000004710105,0.00028891658],"genre_scores_gemma":[0.9985626,0.00012820151,0.000025331676,0.0010461865,0.00010798739,0.00002010994,0.000041102525,0.0000103130305,0.00005819916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928993,0.00013333639,0.00015302112,0.0001809961,0.00009043375,0.00015226928],"domain_scores_gemma":[0.9997463,0.000014195127,0.00005896202,0.000106220694,0.000043275395,0.000031014053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015837439,0.0000925628,0.000103140286,0.000075174205,0.000055373825,0.0000051310267,0.00015434719,0.00010903662,0.000012527032],"category_scores_gemma":[0.00001154582,0.000076929005,0.000039854214,0.0001295439,0.00019008992,0.000003862843,0.00006795352,0.00008186895,0.0000017780836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017722257,0.00012261211,0.0012879373,0.000020737629,0.000028798248,0.00007756474,0.00030932107,0.0011141438,0.9943576,0.00011157421,0.0016950354,0.000697461],"study_design_scores_gemma":[0.0015993227,0.00024762296,0.004572624,0.00000336773,0.000021330166,0.00029803626,0.00013947283,0.0022050862,0.98027587,0.00007694335,0.010414268,0.0001460698],"about_ca_topic_score_codex":0.000008254009,"about_ca_topic_score_gemma":0.0000021167668,"teacher_disagreement_score":0.014081736,"about_ca_system_score_codex":0.0000065612803,"about_ca_system_score_gemma":0.000031704254,"threshold_uncertainty_score":0.31370738},"labels":[],"label_agreement":null},{"id":"W2148786649","doi":"10.1124/mol.112.080879","title":"CB1 Receptor Allosteric Modulators Display Both Agonist and Signaling Pathway Specificity","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Agonist; Allosteric regulation; Chemistry; Allosteric modulator; Receptor; Signal transduction; Biophysics; Biochemistry; Biology","score_opus":0.016536044710268767,"score_gpt":0.30450578777862536,"score_spread":0.2879697430683566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148786649","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99123895,0.0023068187,0.00044611085,0.003539981,0.00064069114,0.0004942442,0.000017780416,0.000050515275,0.0012649047],"genre_scores_gemma":[0.9947285,0.00007226298,0.00028316994,0.0019575271,0.0005376696,0.00006830639,0.00003222849,0.000047079782,0.002273255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982965,0.00016473031,0.0002411799,0.00033003723,0.00029402555,0.0006735282],"domain_scores_gemma":[0.99912256,0.000013935703,0.00006131934,0.00019335755,0.000071883784,0.0005369557],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00038193745,0.0002071117,0.00032462922,0.00012623043,0.00012785778,0.000027307247,0.00009896393,0.00013186937,0.0012319539],"category_scores_gemma":[0.000027349284,0.00018432035,0.0001102894,0.000201198,0.00020393079,0.00007512602,0.0001384404,0.0003557326,0.00007223643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020783079,0.00025354736,0.003757982,0.000085448555,0.000102257676,0.00012454668,0.00018789161,0.000007806453,0.9729102,0.00028881972,0.018824168,0.0032494632],"study_design_scores_gemma":[0.0016392147,0.0003004189,0.006512693,0.0000152008315,0.000109768655,0.00016712402,0.000080864746,0.00023509495,0.7068465,0.00001685485,0.2838321,0.00024419377],"about_ca_topic_score_codex":0.000026980722,"about_ca_topic_score_gemma":8.1717405e-7,"teacher_disagreement_score":0.26606378,"about_ca_system_score_codex":0.00011588287,"about_ca_system_score_gemma":0.00010003216,"threshold_uncertainty_score":0.99968106},"labels":[],"label_agreement":null},{"id":"W2149565581","doi":"10.1124/mol.62.2.250","title":"Cyclic AMP-Mediated Inhibition of 5-Lipoxygenase Translocation and Leukotriene Biosynthesis in Human Neutrophils","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Lipoxygenase; Biosynthesis; Leukotriene; Arachidonate 5-lipoxygenase; Chromosomal translocation; Chemistry; Biochemistry; Leukotriene C4; Leukotriene B4; Enzyme; Biology; Arachidonic acid; Inflammation; Immunology; Gene","score_opus":0.014616901519756439,"score_gpt":0.2594603566381875,"score_spread":0.24484345511843106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149565581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99295324,0.0052263294,0.001001867,0.0004174483,0.00004543528,0.00018306707,0.000010490486,0.000009889843,0.00015221215],"genre_scores_gemma":[0.998444,0.00071009935,0.00013294505,0.00045517305,0.00007602397,0.0000288514,0.0000982787,0.00001965936,0.000034919623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990321,0.00013436528,0.0002771443,0.00028056264,0.00007588779,0.00019998269],"domain_scores_gemma":[0.9996664,0.000016408801,0.000086511485,0.0001266625,0.000040168576,0.000063851956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011345902,0.00013693099,0.00017490804,0.00013859656,0.000037443235,0.000004867747,0.000072326526,0.00014947624,0.0001242555],"category_scores_gemma":[0.0000219014,0.0001496485,0.00005174287,0.00017196526,0.000098504126,0.0000048849442,0.000033219847,0.000087373075,0.0000044824883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038165952,0.0001304952,0.00023382161,0.000022235696,0.000035083944,0.000028079152,0.00006792102,0.000308155,0.99721736,0.000031363754,0.0014836943,0.0004036366],"study_design_scores_gemma":[0.0013718796,0.00014672364,0.0003769679,0.000011244487,0.00003280898,0.000017209532,0.000011222584,0.00021904793,0.99518865,0.00003881754,0.0024380279,0.0001474018],"about_ca_topic_score_codex":0.000033005286,"about_ca_topic_score_gemma":0.0000058897313,"teacher_disagreement_score":0.005490789,"about_ca_system_score_codex":0.000010816248,"about_ca_system_score_gemma":0.000011816097,"threshold_uncertainty_score":0.61024886},"labels":[],"label_agreement":null},{"id":"W2149607387","doi":"10.1124/mol.106.025973","title":"HIV-1 Viral Envelope Glycoprotein gp120 Triggers an Inflammatory Response in Cultured Rat Astrocytes and Regulates the Functional Expression of P-Glycoprotein","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":145,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Astrocyte; Tumor necrosis factor alpha; Cytokine; Immune system; Glycoprotein; Molecular biology; Reverse transcriptase; Immunology; Biochemistry; RNA; Gene; Endocrinology","score_opus":0.0064921775782465115,"score_gpt":0.24177918838301485,"score_spread":0.23528701080476833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149607387","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946942,0.0035437082,0.000121422105,0.00056464033,0.00014777444,0.0007844158,0.000038551374,0.000031816067,0.00007347015],"genre_scores_gemma":[0.9981964,0.000028753546,0.00024446324,0.0000908764,0.000032318,0.00027929212,0.00022497654,0.000017713683,0.00088518707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973136,0.0014749632,0.00034371042,0.00036074582,0.000082172926,0.00042476022],"domain_scores_gemma":[0.9994175,0.00015139433,0.00012029267,0.00020611094,0.00006313603,0.000041585085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050308614,0.00021725253,0.0002752493,0.0001756212,0.00016451598,0.000012526155,0.00018788787,0.00022563373,0.0004836806],"category_scores_gemma":[0.000045812747,0.00015330358,0.00006927756,0.00014034529,0.00049163576,0.000097861026,0.00011300365,0.0003376173,0.000082577295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009808929,0.00023697682,0.0013679245,0.000014044029,0.000071508,0.0001376726,0.0001750103,0.0002379097,0.98511195,0.00007271133,0.0022739635,0.0004913983],"study_design_scores_gemma":[0.0054610344,0.00051297515,0.013715005,0.000017137918,0.000025354917,0.000060857667,0.00009466275,0.000011489815,0.9724602,0.00008463894,0.0074199666,0.00013667907],"about_ca_topic_score_codex":0.00007342986,"about_ca_topic_score_gemma":0.000017046372,"teacher_disagreement_score":0.012651755,"about_ca_system_score_codex":0.00007266046,"about_ca_system_score_gemma":0.00013618406,"threshold_uncertainty_score":0.62515384},"labels":[],"label_agreement":null},{"id":"W2149892146","doi":"10.1124/mol.105.020792","title":"Transactivation of Rat Apical Sodium-Dependent Bile Acid Transporter and Increased Bile Acid Transport by 1α,25-Dihydroxyvitamin D3 via the Vitamin D Receptor","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Calcitriol receptor; Bile acid; Symporter; Ileum; Internal medicine; Bile acid malabsorption; Endocrinology; Small intestine; Duodenum; Jejunum; Biology; Chemistry; Vitamin D and neurology; Biochemistry; Transporter; Medicine","score_opus":0.0036729500571776193,"score_gpt":0.21933936757018974,"score_spread":0.2156664175130121,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149892146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9494468,0.001002867,0.04563318,0.0017285321,0.0004102902,0.0012179932,0.00012099856,0.00007776985,0.00036154897],"genre_scores_gemma":[0.9964488,0.000104763676,0.0006526174,0.0013391731,0.0001405504,0.00019411482,0.00070044864,0.00006440546,0.00035512634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99746037,0.00020582044,0.0006839559,0.0005799307,0.0005636334,0.00050628395],"domain_scores_gemma":[0.9992169,0.000049620194,0.00016014451,0.0003026188,0.00009373814,0.00017698121],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046054588,0.00039869887,0.0006500654,0.00017090571,0.00011850845,0.0000096399335,0.00023612913,0.0003221542,0.0008212503],"category_scores_gemma":[0.0000027886947,0.00030043273,0.00028414067,0.00030836716,0.00029750928,0.000105158986,0.000005227985,0.00043386407,0.000010532708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008964774,0.0009698972,0.00074542133,0.00021170282,0.00015909388,0.0003377271,0.0003823655,0.000007315545,0.99364996,0.00008307511,0.0013298761,0.0012270964],"study_design_scores_gemma":[0.0060628895,0.0004844033,0.002721997,0.00003353861,0.0008385259,0.00006991787,0.00011218332,0.00008105669,0.98067653,0.00008731974,0.008526351,0.00030528283],"about_ca_topic_score_codex":0.00011399228,"about_ca_topic_score_gemma":0.000041126634,"teacher_disagreement_score":0.047001977,"about_ca_system_score_codex":0.000056556404,"about_ca_system_score_gemma":0.00009320725,"threshold_uncertainty_score":0.9999448},"labels":[],"label_agreement":null},{"id":"W2150844644","doi":"10.1124/mol.109.061069","title":"The Small GTPase Ral Couples the Angiotensin II Type 1 Receptor to the Activation of Phospholipase C-δ1","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Phospholipase C; Angiotensin II; Small GTPase; GTP'; Receptor; Cell biology; Small interfering RNA; Endocytosis; Gq alpha subunit; Intracellular; Inositol phosphate; GTPase; Guanine nucleotide exchange factor; Chemistry; Biology; Signal transduction; Inositol; G protein; Biochemistry; RNA; Enzyme","score_opus":0.011890373521858164,"score_gpt":0.2680764282072661,"score_spread":0.25618605468540795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150844644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97376895,0.0021665492,0.0024853642,0.020380152,0.00040061638,0.00065859343,0.000009036219,0.000014284776,0.000116469884],"genre_scores_gemma":[0.9907501,0.00013045475,0.00030014783,0.008078818,0.00026320742,0.000033052336,0.000049733513,0.000015864947,0.00037862925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989127,0.00021185969,0.00022595294,0.00024250105,0.00013884183,0.00026812448],"domain_scores_gemma":[0.9992072,0.00003549237,0.0001244874,0.00036242895,0.00020046106,0.000069953625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004136781,0.00015373313,0.00011993992,0.000027514912,0.0003927379,0.00002038827,0.00035471655,0.00010452759,0.00004268185],"category_scores_gemma":[0.00011200325,0.00008795798,0.00011010761,0.00022939719,0.00012744319,0.0000028284176,0.0001223367,0.00013526034,0.000011101817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003670431,0.0000497131,0.000006220454,0.0000019652148,0.000057912494,0.0000030789633,0.000078953904,0.001581704,0.97087413,0.0003775657,0.01867383,0.007927872],"study_design_scores_gemma":[0.00035186476,0.0002799048,0.0001600182,0.0000049722953,0.00003117327,0.000005911741,0.000027065618,0.0003347751,0.75306195,0.00006326791,0.24558954,0.000089563284],"about_ca_topic_score_codex":0.000019824942,"about_ca_topic_score_gemma":0.000008718269,"teacher_disagreement_score":0.22691572,"about_ca_system_score_codex":0.000017358112,"about_ca_system_score_gemma":0.000092448725,"threshold_uncertainty_score":0.35868222},"labels":[],"label_agreement":null},{"id":"W2151046779","doi":"10.1124/mol.107.039602","title":"Transforming Growth Factor-β1 Impairs Endothelin-1-Mediated Contraction of Brain Vessels by Inducing Mitogen-Activated Protein (MAP) Kinase Phosphatase-1 and Inhibiting p38 MAP Kinase","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Mitogen-activated protein kinase; p38 mitogen-activated protein kinases; Endocrinology; Biology; Internal medicine; Kinase; Protein kinase A; MAPK/ERK pathway; Signal transduction; Hsp27; Cell biology; Biochemistry; Medicine; Heat shock protein; Hsp70","score_opus":0.007219838377279059,"score_gpt":0.2613390623637455,"score_spread":0.2541192239864664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151046779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98687494,0.005210659,0.0058834087,0.00023362588,0.00030110113,0.000998147,0.0004101992,0.000063225896,0.000024700703],"genre_scores_gemma":[0.99786925,0.000039790822,0.00030402344,0.00066996703,0.0001561789,0.00008372027,0.0007470467,0.00008456242,0.000045467837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974836,0.00025485083,0.0006507103,0.000681324,0.00024633517,0.0006831568],"domain_scores_gemma":[0.9987907,0.00013556558,0.00035819548,0.00021119718,0.00019300146,0.00031133764],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004922743,0.0004115461,0.00038539156,0.00016621208,0.00015371383,0.000025879674,0.000214926,0.00037102675,0.0000763846],"category_scores_gemma":[0.00027130859,0.00045651474,0.000138789,0.00017816617,0.00022259176,0.000027892962,0.00008904423,0.00032671023,0.0000053694794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080522563,0.0002688982,0.0002854593,0.00024630487,0.00024293923,0.00015175795,0.00020424179,0.00002072657,0.9952421,0.00001259671,0.00057971984,0.0019400308],"study_design_scores_gemma":[0.0034268135,0.00034541002,0.000084107094,0.00006597623,0.00009464058,0.00001873237,0.00014459681,0.00004197341,0.9903747,0.000015501957,0.0049525197,0.00043501687],"about_ca_topic_score_codex":0.000106069405,"about_ca_topic_score_gemma":0.000009006782,"teacher_disagreement_score":0.01099431,"about_ca_system_score_codex":0.000061839084,"about_ca_system_score_gemma":0.00016819776,"threshold_uncertainty_score":0.99978864},"labels":[],"label_agreement":null},{"id":"W2151217371","doi":"10.1124/mol.108.052860","title":"Multiple Roles of Charged Amino Acids in Cytoplasmic Loop 7 for Expression and Function of the Multidrug and Organic Anion Transporter MRP1 (ABCC1)","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"ABCC1; Transporter; Cytoplasm; Function (biology); Expression (computer science); Organic anion transporter 1; Loop (graph theory); Chemistry; Amino acid; Ion; Multidrug Resistance-Associated Proteins; ATP-binding cassette transporter; Biochemistry; Biology; Cell biology; Gene; Computer science; Organic chemistry; Mathematics; Combinatorics","score_opus":0.009249546317011647,"score_gpt":0.23472939389224134,"score_spread":0.2254798475752297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151217371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940153,0.00066333864,0.004224257,0.0001789782,0.0001669908,0.0007060394,0.000017151238,0.000012097442,0.000015885615],"genre_scores_gemma":[0.9989496,0.0002576147,0.00043637084,0.00017293719,0.000020687345,0.000037358255,0.000021502834,0.000020361247,0.00008355073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918264,0.000047738147,0.00027554444,0.00021639795,0.000114418406,0.00016327553],"domain_scores_gemma":[0.99966043,0.000031247117,0.00009797327,0.00010709613,0.00005169529,0.000051542345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011712814,0.00012691211,0.0003069282,0.00009041862,0.00004850814,8.494102e-7,0.000052661835,0.00011388046,0.000038244118],"category_scores_gemma":[0.000007376896,0.00009220064,0.00007011515,0.00009554394,0.0001378494,0.000035528978,0.000012363149,0.00012274987,2.8071827e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001060215,0.00016855187,0.048714217,0.00021427409,0.00003647887,0.000023507395,0.0006128871,0.000010272865,0.9486573,0.000011237852,0.00002110079,0.0004700091],"study_design_scores_gemma":[0.006238788,0.00018606836,0.10629385,0.00006139085,0.00014828562,0.0000220418,0.00009396507,0.00055704627,0.8860745,0.000023902396,0.000225171,0.00007499302],"about_ca_topic_score_codex":0.000005482685,"about_ca_topic_score_gemma":0.000027074177,"teacher_disagreement_score":0.06258275,"about_ca_system_score_codex":0.000013280496,"about_ca_system_score_gemma":0.00003795644,"threshold_uncertainty_score":0.37598327},"labels":[],"label_agreement":null},{"id":"W2151425122","doi":"10.1124/mol.104.004853","title":"Vascular Endothelial Cell Cyclic Nucleotide Phosphodiesterases and Regulated Cell Migration: Implications in Angiogenesis","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Angiogenesis; Phosphodiesterase 3; Forskolin; Phosphodiesterase; Umbilical vein; Biology; Cell biology; Endothelial stem cell; Cell migration; Pharmacology; Cell; Biochemistry; Enzyme; Cancer research; Receptor","score_opus":0.005723289441968769,"score_gpt":0.2338554010782093,"score_spread":0.22813211163624053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151425122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931319,0.0024775302,0.0023333183,0.0009146737,0.000261129,0.00041452775,0.000024955822,0.000038788025,0.00040318267],"genre_scores_gemma":[0.9962267,0.00081211294,0.00074464467,0.0014964154,0.00010348041,0.00010442299,0.00019810739,0.000038660826,0.0002754568],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864095,0.000115666735,0.00030590082,0.0005189437,0.000100213605,0.0003183137],"domain_scores_gemma":[0.9994057,0.00001635917,0.00010316319,0.00027859432,0.00007165444,0.00012457289],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011587306,0.00023886982,0.00019917208,0.00012769616,0.00011832627,0.000026698923,0.0001359779,0.00019063278,0.000046529345],"category_scores_gemma":[0.00001449985,0.0002534055,0.00012161189,0.00020969208,0.000120371165,0.000011951585,0.00009337151,0.000095298274,0.000015936726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085967455,0.00020431854,0.0029619818,0.00002055536,0.00004138151,0.000019638856,0.00008246814,0.0034601875,0.9922109,0.00006172344,0.0005148732,0.00033600355],"study_design_scores_gemma":[0.0029075504,0.00015873437,0.015944738,0.0000067634855,0.00007161159,0.000025449313,0.000030352958,0.00005773058,0.9626609,0.00014422569,0.017719103,0.00027280848],"about_ca_topic_score_codex":0.00009377739,"about_ca_topic_score_gemma":0.00009005912,"teacher_disagreement_score":0.029549967,"about_ca_system_score_codex":0.000049437105,"about_ca_system_score_gemma":0.00008560845,"threshold_uncertainty_score":0.99999183},"labels":[],"label_agreement":null},{"id":"W2151497596","doi":"10.1124/mol.107.035568","title":"A Peroxisome Proliferator-Activated Receptor γ-Retinoid X Receptor Heterodimer Physically Interacts with the Transcriptional Activator PAX6 to Inhibit Glucagon Gene Transcription","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Retinoid X receptor; Transactivation; Peroxisome proliferator-activated receptor; Glucose homeostasis; Glucagon-like peptide 1 receptor; Thiazolidinedione; Nuclear receptor; Chemistry; Transcription factor; Molecular biology; Glucagon receptor; Biology; Glucagon; Receptor; Cell biology; Endocrinology; Biochemistry; Gene; Insulin; Insulin resistance; Diabetes mellitus","score_opus":0.007452717213880709,"score_gpt":0.2549249122086393,"score_spread":0.24747219499475856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151497596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97938,0.00024246446,0.013047511,0.0043462585,0.0009779892,0.0016286715,0.00011988125,0.0001264301,0.00013076235],"genre_scores_gemma":[0.99006116,0.000056593806,0.0012454425,0.006203055,0.001188633,0.00049835985,0.00031669403,0.00019331777,0.00023671456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99567556,0.00053506816,0.00061201875,0.0012855412,0.0005951827,0.0012966467],"domain_scores_gemma":[0.9981264,0.000057042525,0.00024552338,0.0005420544,0.00041339023,0.0006156155],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00063321897,0.000767851,0.0005091332,0.00024001606,0.00032280665,0.000079690086,0.00064841245,0.0004726605,0.00038861157],"category_scores_gemma":[0.000061729785,0.0005561426,0.00029634332,0.0006162405,0.0003425481,0.000055113916,0.0001285292,0.00066432584,0.00016775665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005910628,0.0004957219,0.00018936304,0.000026961601,0.00060920743,0.000022509234,0.00037761452,0.00007818067,0.9863074,0.000034526034,0.004019243,0.0019286893],"study_design_scores_gemma":[0.0025046477,0.0014077923,0.00022636668,0.00003324982,0.00008739933,0.000053414275,0.00009557185,0.0000050535828,0.9015701,0.0000048116212,0.09331063,0.00070095377],"about_ca_topic_score_codex":0.0000071145455,"about_ca_topic_score_gemma":0.0000081176795,"teacher_disagreement_score":0.089291394,"about_ca_system_score_codex":0.00024994113,"about_ca_system_score_gemma":0.00028084248,"threshold_uncertainty_score":0.999689},"labels":[],"label_agreement":null},{"id":"W2151849193","doi":"10.1124/mol.111.071027","title":"In Vivo Labeling of Brain Capillary Endothelial Cells after Intravenous Injection of Monoclonal Antibodies Targeting the Transferrin Receptor","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Alexa Fluor; Transferrin receptor; Colocalization; Monoclonal antibody; Pericyte; Transferrin; Molecular biology; Antibody; Glial fibrillary acidic protein; Blood–brain barrier; Confocal microscopy; Biology; In vivo; Chemistry; Cell biology; Pathology; Central nervous system; Endothelial stem cell; Immunohistochemistry; Immunology; In vitro; Biochemistry; Fluorescence; Endocrinology; Medicine","score_opus":0.01700395310205761,"score_gpt":0.25366343481054293,"score_spread":0.23665948170848533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151849193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99659944,0.0003442261,0.0007187841,0.00023244276,0.0012496115,0.00023468371,0.000046043904,0.000014918835,0.000559831],"genre_scores_gemma":[0.99790645,0.00014450417,0.00035432263,0.0014393367,0.00007373612,0.000028572984,4.1769408e-7,0.0000147299015,0.000037906604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873537,0.00032107165,0.0003373302,0.0002451363,0.00013394856,0.00022714444],"domain_scores_gemma":[0.9996076,0.00012890717,0.000099289246,0.000091359565,0.000045272147,0.000027577024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020664159,0.00013522414,0.00023318394,0.00011775185,0.00006413931,0.0000031233694,0.00015213521,0.000070794165,0.00054866157],"category_scores_gemma":[0.000051380888,0.000106868734,0.00007677874,0.00021247673,0.00026906395,0.000060067447,0.00005500903,0.0002021947,0.0000036975916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003563618,0.000060106177,0.00034526363,0.000028320828,0.000028754535,0.000038844966,0.004530524,0.00008641271,0.9934921,0.00014887784,0.0006875881,0.0001968155],"study_design_scores_gemma":[0.0005287614,0.00017852953,0.00013589741,0.000005854561,0.000029815128,0.000017746193,0.00017130746,0.00005026815,0.9970819,0.00024545626,0.0014611837,0.000093287344],"about_ca_topic_score_codex":0.00013547868,"about_ca_topic_score_gemma":0.000012266057,"teacher_disagreement_score":0.0043592164,"about_ca_system_score_codex":0.000015380081,"about_ca_system_score_gemma":0.000031186595,"threshold_uncertainty_score":0.6007459},"labels":[],"label_agreement":null},{"id":"W2152553804","doi":"10.1124/mol.113.089003","title":"Endocytic Profiles of δ-Opioid Receptor Ligands Determine the Duration of Rapid but Not Sustained cAMP Responses","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Québec Consortium for Drug Discovery","keywords":"Internalization; Chemistry; Enkephalin; Opioid receptor; Ligand (biochemistry); Receptor; Opioid; Biophysics; Stereochemistry; Biochemistry; Biology","score_opus":0.009705185968700214,"score_gpt":0.2565868865312578,"score_spread":0.24688170056255757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152553804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961004,0.0006575144,0.0018140048,0.00037425113,0.00029121427,0.0006485026,0.000024396075,0.00000987737,0.000079817066],"genre_scores_gemma":[0.99776894,0.00019384356,0.0007549921,0.00047557635,0.00014260704,0.0001559679,0.00005745049,0.000027166512,0.00042346484],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860877,0.0002363205,0.0004475045,0.00027782688,0.00015766539,0.00027190553],"domain_scores_gemma":[0.99903995,0.000065847205,0.00027403623,0.00026838013,0.00028829311,0.00006348308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030946088,0.00017968159,0.00024973167,0.000075998105,0.00006661903,0.00001161276,0.00027812013,0.00015024884,0.0009047042],"category_scores_gemma":[0.00014994283,0.00013757273,0.00014305681,0.000109798,0.00016081189,0.000006832331,0.00011663223,0.000103691,0.000010707631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003590524,0.00005794354,0.000042546166,0.000051557894,0.000109702996,0.000004764681,0.00009545427,0.00003390218,0.99694514,0.00008622979,0.0009560135,0.0012577187],"study_design_scores_gemma":[0.0008499618,0.00068354607,0.000082571416,0.000008753121,0.00005816198,0.000014071592,0.00019509428,0.00027265263,0.99579364,0.000061052546,0.001840139,0.00014033321],"about_ca_topic_score_codex":0.00003141103,"about_ca_topic_score_gemma":0.000001048426,"teacher_disagreement_score":0.001668509,"about_ca_system_score_codex":0.000015796473,"about_ca_system_score_gemma":0.00015225695,"threshold_uncertainty_score":0.99058765},"labels":[],"label_agreement":null},{"id":"W2152791101","doi":"10.1124/mol.109.058834","title":"Analgesic ω-Conotoxins CVIE and CVIF Selectively and Voltage-Dependently Block Recombinant and Native N-Type Calcium Channels","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institutes of Health","keywords":"Voltage-dependent calcium channel; Calcium channel; Chemistry; Analgesic; N-type calcium channel; Block (permutation group theory); Calcium; L-type calcium channel; Conotoxin; Pharmacology; T-type calcium channel; Medicine; Mathematics; Biochemistry; Peptide; Combinatorics","score_opus":0.010579916056177597,"score_gpt":0.292947757616527,"score_spread":0.28236784156034944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152791101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992315,0.004892064,0.00068656873,0.00066621683,0.00041361555,0.0006047953,0.000009080871,0.00002800121,0.0003846916],"genre_scores_gemma":[0.99621344,0.0013214261,0.00019173215,0.001554579,0.00016743022,0.000026053214,0.000022398748,0.000035626173,0.00046731453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981527,0.00021421758,0.00026770268,0.00077609636,0.00012012817,0.0004692075],"domain_scores_gemma":[0.99930316,0.00002988314,0.00012703367,0.00016908578,0.00014650152,0.00022430735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027434723,0.00033542202,0.00036334258,0.00010646449,0.0001593692,0.000035164685,0.00015140846,0.00024263929,0.00002236706],"category_scores_gemma":[0.00007907092,0.0003397456,0.00005371307,0.00016968024,0.00019663002,0.0000099326135,0.00023457823,0.00027666532,0.000004219263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001862766,0.00014113392,0.00095411716,0.000014888228,0.00021786924,0.000022312834,0.00016115025,0.000009595905,0.99380404,0.00008271722,0.0020786012,0.0023272934],"study_design_scores_gemma":[0.0032000262,0.0021177665,0.0029315255,0.0000104216415,0.00018449937,0.00028491043,0.00008296149,0.00027890943,0.97823393,0.00027266733,0.011904602,0.00049775897],"about_ca_topic_score_codex":0.000023061624,"about_ca_topic_score_gemma":0.0000075207613,"teacher_disagreement_score":0.015570093,"about_ca_system_score_codex":0.000028629063,"about_ca_system_score_gemma":0.00008248644,"threshold_uncertainty_score":0.99990547},"labels":[],"label_agreement":null},{"id":"W2153195809","doi":"10.1124/mol.106.025841","title":"Analysis of the Dissociated Steroid RU24858 Does Not Exclude a Role for Inducible Genes in the Anti-Inflammatory Actions of Glucocorticoids","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Sanofi","keywords":"Transrepression; Transactivation; Glucocorticoid receptor; Psychological repression; Glucocorticoid; Gene expression; Biology; Transcription factor; Transcription (linguistics); Gene; Molecular biology; Internal medicine; Endocrinology; Medicine; Biochemistry","score_opus":0.006853735887540895,"score_gpt":0.27283419770409584,"score_spread":0.26598046181655494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153195809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976635,0.0010106605,0.00022496538,0.0002448682,0.00014894395,0.00052390253,0.000052987125,0.0000055675755,0.00012458401],"genre_scores_gemma":[0.9993442,0.000083252016,0.00004105656,0.00019811711,0.000053056505,0.00011314072,0.00007495801,0.00001599255,0.000076208984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874216,0.00029523845,0.00034806703,0.00024549643,0.00012843656,0.00024058112],"domain_scores_gemma":[0.999319,0.000049311373,0.00022809958,0.00029845125,0.00008135082,0.000023776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028432382,0.00014143556,0.00026667802,0.00013170489,0.00007534263,0.000006669156,0.00032565012,0.0002083489,0.0000075671583],"category_scores_gemma":[0.00002501548,0.00008563267,0.00033796648,0.0004719742,0.00015451566,0.0000035352953,0.000083609884,0.00013144988,4.181631e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008625674,0.00020975186,0.015377926,0.000018514342,0.00080438866,0.0000041330545,0.00006985057,0.0030963775,0.9799588,0.00008418104,0.00010623965,0.00018361934],"study_design_scores_gemma":[0.00085552706,0.00010009374,0.032957006,0.0000038080311,0.0009704724,0.0000028864508,0.000076010605,0.00062854734,0.96352136,0.0000377357,0.00074781495,0.00009875072],"about_ca_topic_score_codex":0.00008764441,"about_ca_topic_score_gemma":0.0000699637,"teacher_disagreement_score":0.017579082,"about_ca_system_score_codex":0.000015554204,"about_ca_system_score_gemma":0.00006985989,"threshold_uncertainty_score":0.3491999},"labels":[],"label_agreement":null},{"id":"W2154101477","doi":"10.1124/mol.105.015768","title":"A Comparison of the Transportability, and Its Role in Cytotoxicity, of Clofarabine, Cladribine, and Fludarabine by Recombinant Human Nucleoside Transporters Produced in Three Model Expression Systems","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoside transporter; Cladribine; Nucleoside; Nucleoside analogue; Clofarabine; Biochemistry; Biology; Fludarabine; Cytotoxicity; Chemistry; Transporter; Cytarabine; Leukemia; In vitro; Immunology","score_opus":0.014123503035079268,"score_gpt":0.2940807132762104,"score_spread":0.2799572102411311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154101477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99090546,0.007829959,0.00026982996,0.00025253053,0.00004378504,0.0006362605,0.000023530001,0.000004791105,0.000033878423],"genre_scores_gemma":[0.99961334,0.000105424326,0.00007307181,0.00007380396,0.00001986619,0.000047872556,0.000029481704,0.000021353231,0.00001577121],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984986,0.00012804048,0.0006083213,0.00040412584,0.00012613715,0.0002347285],"domain_scores_gemma":[0.9995137,0.000010528638,0.00018183226,0.000191553,0.00004633368,0.000056071494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026451136,0.00019087455,0.00041171032,0.00007431506,0.00003471129,0.0000037787902,0.00019461392,0.00017531462,0.000005590713],"category_scores_gemma":[0.0000085188585,0.00016217663,0.00006112605,0.00012673446,0.00011310915,0.000009073409,0.000064261,0.00018422041,6.778202e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016244203,0.00036524463,0.055454288,0.00011968386,0.000021910773,0.0000029750227,0.00022240634,0.013324766,0.9300386,0.000041919895,0.00019338094,0.000052398478],"study_design_scores_gemma":[0.002075907,0.00019403682,0.0076223644,0.000056803143,0.000040509338,0.000006114501,0.000043795655,0.018253943,0.97144127,0.00004356957,0.00006358151,0.00015813163],"about_ca_topic_score_codex":0.00008906764,"about_ca_topic_score_gemma":0.00008075065,"teacher_disagreement_score":0.047831923,"about_ca_system_score_codex":0.000014662283,"about_ca_system_score_gemma":0.00003884437,"threshold_uncertainty_score":0.66133714},"labels":[],"label_agreement":null},{"id":"W2154667571","doi":"10.1124/mol.105.011296","title":"Nuclear Factor-κB Decoys Suppress Endotoxin-Induced Lung Injury","year":2005,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Immune system; Repertoire; Immunology; Biology; Key (lock); Host (biology); Inflammation; Genetics; Ecology","score_opus":0.03090743683749916,"score_gpt":0.3670350236055048,"score_spread":0.33612758676800564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154667571","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007686474,0.9873451,0.00016078138,0.000043287455,0.0016577949,0.0016152308,0.00036416776,0.00012583799,0.0010013125],"genre_scores_gemma":[0.008819806,0.98590344,0.00042088932,0.0013003178,0.0015688243,0.00033788822,0.0007988389,0.00046005045,0.00038995335],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9951469,0.00090494566,0.00096225785,0.0015375246,0.0003466968,0.0011017112],"domain_scores_gemma":[0.9978256,0.000055106982,0.00055728183,0.0010231694,0.00014026278,0.00039853674],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027641893,0.0011294299,0.0017426638,0.00030680935,0.00016963003,0.00006811952,0.0014049886,0.0015343825,0.0010572935],"category_scores_gemma":[0.00007509164,0.0011545891,0.0011278082,0.00027030875,0.0001560352,0.000008065207,0.0008183031,0.0010107583,0.00037656902],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046366702,0.00016895749,9.2799394e-7,0.0014860525,0.0009839056,0.00025722935,0.000022111146,0.000006301124,0.75895596,0.000029727391,0.012001009,0.22604147],"study_design_scores_gemma":[0.0005464305,0.00022702344,3.280306e-7,0.00026550196,0.00088330585,0.00016007076,0.0000026956243,0.000013745556,0.20595686,0.0000029100138,0.79105955,0.00088155596],"about_ca_topic_score_codex":0.000008422742,"about_ca_topic_score_gemma":0.0000023020473,"teacher_disagreement_score":0.7790586,"about_ca_system_score_codex":0.00018342283,"about_ca_system_score_gemma":0.0005385525,"threshold_uncertainty_score":0.9998559},"labels":[],"label_agreement":null},{"id":"W2154904638","doi":"10.1124/mol.64.6.1512","title":"Uridine Binding Motifs of Human Concentrative Nucleoside Transporters 1 and 3 Produced in Saccharomyces cerevisiae","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Uridine; Nucleoside; Biochemistry; Footprinting; Uracil; Stereochemistry; Yeast; Biology; Chemistry; RNA; DNA; Gene","score_opus":0.009322523561867982,"score_gpt":0.2770774916415223,"score_spread":0.2677549680796543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154904638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99543613,0.0034288105,0.00022104215,0.00013015034,0.00008325659,0.00026913834,0.000008469645,0.000006747437,0.0004162271],"genre_scores_gemma":[0.9992587,0.0001568432,0.00019162569,0.00022592106,0.00004260715,0.00001960197,0.000036263547,0.000021175149,0.000047277146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886096,0.00016146728,0.00028373708,0.0003622726,0.00007527741,0.00025627157],"domain_scores_gemma":[0.9996535,0.000011284167,0.0001062155,0.00011929743,0.000040514104,0.000069167494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018316388,0.00016580094,0.00023950954,0.000078874706,0.000041379186,0.0000058148953,0.000103819235,0.000101999954,0.000095997406],"category_scores_gemma":[0.000020305934,0.00017141279,0.00005710665,0.00012520082,0.000115654366,0.000005114172,0.000024047293,0.000107395754,0.0000010461132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004177049,0.00007346611,0.008971795,0.00003866945,0.00007874946,0.000057112666,0.00015765116,0.00011420759,0.9894848,0.00027685138,0.00064574706,0.000059163634],"study_design_scores_gemma":[0.0014424929,0.00023469563,0.00078963063,0.00001642153,0.000050397906,0.000022700038,0.00009636133,0.000015337162,0.9956488,0.000040441693,0.0014738089,0.00016890648],"about_ca_topic_score_codex":0.000015077804,"about_ca_topic_score_gemma":0.0000017937624,"teacher_disagreement_score":0.008182164,"about_ca_system_score_codex":0.000010658249,"about_ca_system_score_gemma":0.00004696314,"threshold_uncertainty_score":0.6990011},"labels":[],"label_agreement":null},{"id":"W2155022928","doi":"10.1124/mol.113.091090","title":"Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface–Resident Bile Salt Export Pump and Multidrug Resistance–Associated Protein 2","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Innovation Cluster (Canada)","funders":"","keywords":"Ubiquitin; Multiple drug resistance; Mechanism (biology); Cell biology; Chemistry; Bile Salt Export Pump; Degradation (telecommunications); Salt (chemistry); Biochemistry; Biology; Gene; Computer science","score_opus":0.006954667254598012,"score_gpt":0.24519229361733635,"score_spread":0.23823762636273835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155022928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98962265,0.00011503036,0.008602742,0.00039010748,0.00009633827,0.00089530606,0.000011044676,0.000017104216,0.00024966677],"genre_scores_gemma":[0.99885327,0.00004491661,0.0005001813,0.00010482228,0.000017991364,0.000051516385,0.00007260748,0.000018946756,0.00033573146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985576,0.00028138,0.00041437193,0.00022494335,0.0003219575,0.00019973172],"domain_scores_gemma":[0.99940085,0.000049232247,0.0002519465,0.00014119342,0.00011141092,0.000045388217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005019688,0.00014207848,0.00035107287,0.0001130117,0.00003786431,0.0000046002324,0.0001100137,0.00011443063,0.000078152094],"category_scores_gemma":[0.000026705819,0.0001098549,0.00007581846,0.00016348308,0.0000762188,0.000034663557,0.000019016357,0.00015643728,9.147503e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002400516,0.00038468855,0.00025306194,0.00022185993,0.000035900983,0.00003110194,0.00062641874,0.000018843164,0.9962667,0.0018213884,0.000018792789,0.00008117669],"study_design_scores_gemma":[0.0034148474,0.00017527345,0.0034398155,0.00008172326,0.00016553623,0.0000016019453,0.00030365924,0.00093192694,0.99062085,0.00071976753,0.000051174648,0.00009380076],"about_ca_topic_score_codex":0.00002809151,"about_ca_topic_score_gemma":0.00011951017,"teacher_disagreement_score":0.009230626,"about_ca_system_score_codex":0.000033220782,"about_ca_system_score_gemma":0.000050289353,"threshold_uncertainty_score":0.44797528},"labels":[],"label_agreement":null},{"id":"W2155202772","doi":"10.1124/mol.104.004978","title":"Characterization of Binding of Folates and Antifolates to Brush-Border Membrane Vesicles Isolated from Human Kidney","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"AstraZeneca","keywords":"Brush border; Vesicle; Chemistry; Biochemistry; Brush; Kidney; Membrane; Biology; Endocrinology","score_opus":0.00454550062736933,"score_gpt":0.2597125529197061,"score_spread":0.25516705229233677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155202772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99748635,0.00009517383,0.0016775326,0.00026006883,0.0001827418,0.00017989863,0.000058197216,0.0000107189935,0.000049323324],"genre_scores_gemma":[0.9984264,0.00005759619,0.00049246283,0.0005623273,0.0000795279,0.0000046658333,0.00033420915,0.000023849076,0.00001898324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992641,0.000044236123,0.00022769127,0.0002568892,0.0000635838,0.0001434601],"domain_scores_gemma":[0.9995948,0.0000042261736,0.00012087626,0.0001250905,0.000071187016,0.000083814855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054357537,0.00012625873,0.00018570472,0.00008569123,0.0000451973,0.0000069742678,0.000092486174,0.00013737494,0.00008285684],"category_scores_gemma":[0.00001688923,0.00013070567,0.00004628594,0.0001191927,0.00006204554,0.000006292369,0.00007864178,0.000059119535,0.0000026980194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013619993,0.00003533212,0.0007595734,0.000023084613,0.0001583275,0.000003648028,0.00010560018,0.000040937866,0.99807847,0.000056347333,0.00002785537,0.0005746347],"study_design_scores_gemma":[0.001014718,0.00034848973,0.004875738,0.000015519172,0.0000813123,0.000004468372,0.000011208104,0.000020983614,0.99147666,0.00007127067,0.0019563937,0.00012324368],"about_ca_topic_score_codex":0.000071212395,"about_ca_topic_score_gemma":0.0000051971483,"teacher_disagreement_score":0.0066018044,"about_ca_system_score_codex":0.000006732736,"about_ca_system_score_gemma":0.000028901968,"threshold_uncertainty_score":0.5330022},"labels":[],"label_agreement":null},{"id":"W2155547273","doi":"10.1124/mol.106.026716","title":"Distinct Signaling Profiles of β1 and β2 Adrenergic Receptor Ligands toward Adenylyl Cyclase and Mitogen-Activated Protein Kinase Reveals the Pluridimensionality of Efficacy","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":286,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"GlaxoSmithKline","keywords":"Adenylyl cyclase; Receptor; Protein kinase A; Effector; Signal transduction; MAPK/ERK pathway; Intrinsic activity; Inverse agonist; G protein-coupled receptor; Functional selectivity; Ligand (biochemistry); cAMP-dependent pathway; Biology; Chemistry; Cell biology; Biochemistry; Pharmacology; Kinase; Agonist","score_opus":0.009112526610595445,"score_gpt":0.2492321039072224,"score_spread":0.24011957729662695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155547273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99530345,0.0031946057,0.0004742234,0.0002115761,0.00013226386,0.00058780436,0.000053804255,0.00001103839,0.000031250147],"genre_scores_gemma":[0.9986656,0.000055063592,0.0007450536,0.00010200548,0.0001341852,0.00006294761,0.00011197202,0.000029023697,0.00009420356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845606,0.00023314197,0.00044117385,0.00043286546,0.00017134075,0.00026539827],"domain_scores_gemma":[0.9992436,0.000050191953,0.0002758971,0.00019463358,0.0001498841,0.000085796346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037342997,0.00023772923,0.00033584156,0.000053037573,0.00009541056,0.0000120150435,0.0001567167,0.00018311075,0.00011128887],"category_scores_gemma":[0.00006605995,0.00018712066,0.00010646252,0.00012269404,0.0002665951,0.000005362904,0.00017396145,0.00013487542,5.100646e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037617233,0.00012675386,0.00024092502,0.00009217796,0.00011939991,0.000010688441,0.000054870583,0.00011793736,0.9981027,0.00019415714,0.00027487366,0.00028932592],"study_design_scores_gemma":[0.0013454738,0.00033047888,0.00032484077,0.00004188085,0.00009151518,0.000013371116,0.000035661084,0.000066858265,0.99657017,0.00018710233,0.00079526776,0.00019737838],"about_ca_topic_score_codex":0.000060281403,"about_ca_topic_score_gemma":0.00000162465,"teacher_disagreement_score":0.0033621115,"about_ca_system_score_codex":0.000009604561,"about_ca_system_score_gemma":0.000071651855,"threshold_uncertainty_score":0.7630559},"labels":[],"label_agreement":null},{"id":"W2155954855","doi":"10.1124/mol.65.2.407","title":"Vanadate Is a Potent Activator of Endothelial Nitric-Oxide Synthase: Evidence for the Role of the Serine/Threonine Kinase Akt and the 90-kDa Heat Shock Protein","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Heart, Lung, and Blood Institute","keywords":"Vanadate; Enos; Phosphorylation; Protein kinase B; Nitric Oxide Synthase Type III; Ionomycin; Wortmannin; Endothelial NOS; Chemistry; Nitric oxide synthase; Nitric oxide; Biochemistry; Biology; Molecular biology; Internal medicine; Endocrinology; Medicine; Intracellular","score_opus":0.013177534739382742,"score_gpt":0.2883010585731524,"score_spread":0.27512352383376965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155954855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783437,0.0059735775,0.0012264735,0.010766323,0.00013079777,0.0034247485,0.00006114474,0.000017785487,0.000055414344],"genre_scores_gemma":[0.9961504,0.00024256967,0.00035624122,0.0025155784,0.00011807342,0.00047135644,0.0000016515901,0.000034563785,0.00010959734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984246,0.00023661736,0.00037060166,0.00029460457,0.00032498714,0.00034857754],"domain_scores_gemma":[0.9984464,0.0006781727,0.00017551036,0.000458399,0.00014429743,0.00009721958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054847344,0.00023095278,0.00046211795,0.00006823217,0.00014171275,0.000008209737,0.0003381128,0.0000886787,0.0000500566],"category_scores_gemma":[0.0004213742,0.000116028255,0.00024925586,0.0002819072,0.00037726993,0.00005118282,0.00017335937,0.0002866258,0.0000023686064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032862346,0.0001866503,0.00014798464,0.00019495779,0.00035670187,0.0000412967,0.00012474631,0.0003361358,0.9929611,0.00038220105,0.00016229817,0.0018196554],"study_design_scores_gemma":[0.008748605,0.00034491243,0.00032092055,0.00016502012,0.00076302537,0.00010398807,0.00008434978,0.00078040577,0.9847797,0.0007633587,0.0030361088,0.00010956524],"about_ca_topic_score_codex":0.0010438884,"about_ca_topic_score_gemma":0.000011889399,"teacher_disagreement_score":0.017806632,"about_ca_system_score_codex":0.00007033781,"about_ca_system_score_gemma":0.00027148266,"threshold_uncertainty_score":0.47314948},"labels":[],"label_agreement":null},{"id":"W2156420135","doi":"10.1124/mol.108.049080","title":"Mechanistic Differences between GSH Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) and GSH Modulation of MRP1-Mediated Transport","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"ABCC1; Multiple drug resistance; Multidrug Resistance-Associated Proteins; Glutathione; Chemistry; Biology; ATP-binding cassette transporter; Biochemistry; Transporter; Gene; Antibiotics; Enzyme","score_opus":0.013162247196895679,"score_gpt":0.24718469152853156,"score_spread":0.23402244433163588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156420135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95577854,0.0007761037,0.04061716,0.00053791906,0.00014286762,0.0014088504,0.0002721424,0.00012167673,0.00034477076],"genre_scores_gemma":[0.99511415,0.00023030405,0.0018648471,0.00021255376,0.00006878432,0.00013976397,0.00048895704,0.00006321164,0.001817433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997526,0.00010872115,0.00072934857,0.00062117446,0.0005187086,0.0004960758],"domain_scores_gemma":[0.99902165,0.00005250753,0.00023166562,0.0002432631,0.00014990542,0.0003009986],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023791596,0.00038777234,0.00088687346,0.00018446805,0.00014548744,0.0000026894368,0.00017833016,0.0002876297,0.00021739295],"category_scores_gemma":[0.00001284275,0.0003603632,0.00017581979,0.0003255953,0.00034063673,0.00008024509,0.000009799744,0.0003557836,0.000005807835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064473273,0.00030359754,0.0154394675,0.00046972535,0.00025511227,0.00072172016,0.0004622508,0.000007989067,0.981076,0.00028383386,0.00010128238,0.00023426225],"study_design_scores_gemma":[0.006730949,0.00044443403,0.15907463,0.00020731454,0.00091299496,0.000032527467,0.000067449786,0.00037246314,0.8291551,0.0007056134,0.0017136007,0.0005829283],"about_ca_topic_score_codex":0.000058488935,"about_ca_topic_score_gemma":0.000035340843,"teacher_disagreement_score":0.15192094,"about_ca_system_score_codex":0.000047728423,"about_ca_system_score_gemma":0.00015050797,"threshold_uncertainty_score":0.99988484},"labels":[],"label_agreement":null},{"id":"W2156437245","doi":"10.1124/mol.60.1.92","title":"Dopamine D<sub>4</sub>and D<sub>2L</sub>Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on<i>trans-</i>Activation of the Platelet-Derived Growth Factor Receptor","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Platelet-derived growth factor receptor; Wortmannin; Autophosphorylation; Biology; Tyrosine kinase; Chemistry; Receptor; Cell biology; Molecular biology; Protein kinase A; Signal transduction; Kinase; Biochemistry; Protein kinase B; Growth factor","score_opus":0.00963308136360346,"score_gpt":0.22664769895354178,"score_spread":0.2170146175899383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156437245","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938639,0.00018679566,0.0035090144,0.00040045078,0.000558658,0.0013407577,0.00010130057,0.000017546367,0.000021568754],"genre_scores_gemma":[0.9988193,0.00017196262,0.00009239383,0.0005243763,0.00013021611,0.00010393386,0.0000729819,0.00006149089,0.000023367229],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977166,0.00045809263,0.0005105148,0.00056303304,0.0003755127,0.00037625883],"domain_scores_gemma":[0.99876314,0.000039968018,0.00044893497,0.00037279725,0.000267411,0.00010774236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020421059,0.0003667319,0.00034533264,0.00008688034,0.00017230594,0.000016587082,0.00035453463,0.00034303105,0.00014047931],"category_scores_gemma":[0.00008670724,0.00027422936,0.00024071654,0.00028757507,0.0001710441,0.000016125616,0.00015439434,0.00029096554,0.000003561252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007384342,0.00020337291,0.00012820937,0.00005459799,0.00020628885,0.0000029050057,0.00015537131,0.0003648057,0.9943715,0.000029448873,0.000113755545,0.0036313443],"study_design_scores_gemma":[0.002010952,0.00044401188,0.0003874769,0.00005341569,0.000044669992,0.000007362779,0.000027153974,0.0001434147,0.99553084,0.000047647092,0.001017367,0.00028569388],"about_ca_topic_score_codex":0.000020725629,"about_ca_topic_score_gemma":0.0000039954134,"teacher_disagreement_score":0.0049553695,"about_ca_system_score_codex":0.000055540673,"about_ca_system_score_gemma":0.00012594754,"threshold_uncertainty_score":0.999971},"labels":[],"label_agreement":null},{"id":"W2156527651","doi":"10.1124/mol.112.082347","title":"Small Molecule Inhibitors of ERCC1-XPF Protein-Protein Interaction Synergize Alkylating Agents in Cancer Cells","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Illinois at Urbana-Champaign; National Science Council; Ministry of Advanced Education, Government of Alberta","keywords":"ERCC1; Nucleotide excision repair; Cancer cell; In silico; Cisplatin; DNA repair; Cytotoxicity; Cancer; Biology; DNA damage; Cancer research; Chemistry; DNA; Biochemistry; In vitro; Genetics; Chemotherapy","score_opus":0.018122654675376923,"score_gpt":0.2891380682068525,"score_spread":0.27101541353147557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156527651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99608517,0.00039634536,0.0007793897,0.00020224738,0.00045982873,0.0014985155,0.000009142421,0.000027717375,0.0005416612],"genre_scores_gemma":[0.99660075,0.000027143897,0.0013290531,0.0004980749,0.00011792351,0.00094430515,0.000032038904,0.00006656467,0.0003841427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979255,0.00031150717,0.000513541,0.0005849382,0.0001740962,0.0004904221],"domain_scores_gemma":[0.9991321,0.000008499716,0.0002769395,0.00030608615,0.00015060011,0.00012578706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019896918,0.00029474602,0.00030073948,0.00016434332,0.00003930665,0.000017606488,0.00030915652,0.0002751781,0.0005213113],"category_scores_gemma":[0.000030391995,0.00032280176,0.00015448588,0.0002135845,0.00007834488,0.000012968065,0.00027292548,0.00026061668,0.000038835584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006070068,0.00017795434,0.000113653536,0.00006707934,0.00009954778,0.00004254665,0.00005054474,0.0005895444,0.99538267,0.00002522001,0.00060215703,0.002788398],"study_design_scores_gemma":[0.0011645939,0.0002995453,0.00007704715,0.000052479932,0.000031963304,0.0000060627603,0.00007407036,0.00070439564,0.99598014,0.00006504196,0.0012488778,0.0002957501],"about_ca_topic_score_codex":0.0008249747,"about_ca_topic_score_gemma":0.00007917774,"teacher_disagreement_score":0.0024926479,"about_ca_system_score_codex":0.000081752194,"about_ca_system_score_gemma":0.00011214182,"threshold_uncertainty_score":0.9999224},"labels":[],"label_agreement":null},{"id":"W2156615759","doi":"10.1124/mol.105.017467","title":"Direct Stimulation of KATP Channels by Exogenous and Endogenous Hydrogen Sulfide in Vascular Smooth Muscle Cells","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":294,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University; University of Saskatchewan","funders":"","keywords":"Endogeny; Vascular smooth muscle; Potassium channel; Biophysics; Membrane potential; Patch clamp; Stimulation; Chemistry; Ion channel; Sulfonylurea receptor; ATP-sensitive potassium channel; Cell biology; Biochemistry; Biology; Endocrinology; Glibenclamide; Receptor; Smooth muscle; Protein subunit","score_opus":0.011708110080925784,"score_gpt":0.24972979385054414,"score_spread":0.23802168376961835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156615759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98814404,0.0095428005,0.0007570952,0.00009810233,0.00025017123,0.00049635343,0.00003529311,0.000021946576,0.00065418944],"genre_scores_gemma":[0.99737114,0.0007347493,0.0006623655,0.00077836873,0.00016501012,0.00006600684,0.00013235051,0.000050743372,0.00003929217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797255,0.00035585105,0.00042495748,0.00061346445,0.00013823048,0.00049494713],"domain_scores_gemma":[0.9992794,0.000047691472,0.00014969357,0.00033229325,0.00007459819,0.00011635653],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003534346,0.00027980428,0.00037971116,0.0001436935,0.000054674598,0.000008711945,0.00028798642,0.00030607026,0.00006126946],"category_scores_gemma":[0.00003371737,0.00031166134,0.000118323514,0.00016494075,0.00020164943,0.000006924855,0.0002096557,0.00014165496,0.000009572802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009185672,0.00024245391,0.00034187504,0.000019591123,0.00012317169,0.00003692433,0.00011483267,0.005863759,0.9894952,0.000008842283,0.00046919225,0.0031922765],"study_design_scores_gemma":[0.0018016114,0.00035196394,0.000276602,0.0000044980006,0.00006372693,0.00001526489,0.000013901244,0.0006899671,0.9552016,0.000030562092,0.04126619,0.0002841033],"about_ca_topic_score_codex":0.00007559266,"about_ca_topic_score_gemma":0.000019444215,"teacher_disagreement_score":0.040797,"about_ca_system_score_codex":0.000047878708,"about_ca_system_score_gemma":0.0000657026,"threshold_uncertainty_score":0.99993354},"labels":[],"label_agreement":null},{"id":"W2156786487","doi":"10.1124/mol.110.069054","title":"Differential Signaling of Cysteinyl Leukotrienes and a Novel Cysteinyl Leukotriene Receptor 2 (CysLT2) Agonist, N-Methyl-Leukotriene C4, in Calcium Reporter and β Arrestin Assays","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Agonist; G protein-coupled receptor; Chemistry; Biology; Biochemistry","score_opus":0.010240849565149365,"score_gpt":0.2652310063006385,"score_spread":0.25499015673548914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156786487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747332,0.0008540199,0.022442205,0.00016130219,0.0010709706,0.0005311283,0.000044714256,0.0000254274,0.00013706327],"genre_scores_gemma":[0.9951858,0.0000984852,0.0037002086,0.00023861046,0.00035690144,0.000093769326,0.00011447313,0.000074394266,0.0001373528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970747,0.00020715082,0.00084588316,0.00096473336,0.00027986264,0.0006276466],"domain_scores_gemma":[0.9986827,0.000075047836,0.00039222825,0.00038729954,0.00018673185,0.00027603676],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006345926,0.00045875687,0.0006457099,0.00024307339,0.00012718455,0.000049382583,0.0002853559,0.0005517474,0.00024066227],"category_scores_gemma":[0.00018456312,0.00046229197,0.00015294513,0.00023585842,0.00033659523,0.000017187669,0.00035384326,0.00045760974,0.0000018040724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034999906,0.00017169442,0.00092187664,0.00008780617,0.00012683115,0.000085431595,0.00011935617,0.000113540125,0.99645233,0.0003250294,0.00013087656,0.0011152171],"study_design_scores_gemma":[0.003216513,0.00048578193,0.00022019638,0.000031269377,0.00011102378,0.00018416217,0.000089122586,0.0007554885,0.9903779,0.00012140213,0.003932698,0.00047446424],"about_ca_topic_score_codex":0.0001154914,"about_ca_topic_score_gemma":0.000038105805,"teacher_disagreement_score":0.020452635,"about_ca_system_score_codex":0.000025567162,"about_ca_system_score_gemma":0.00018000155,"threshold_uncertainty_score":0.99978286},"labels":[],"label_agreement":null},{"id":"W2157037954","doi":"10.1124/mol.111.073833","title":"Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter","year":2011,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Barbara Ann Karmanos Cancer Institute; Mesothelioma Applied Research Foundation","keywords":"HeLa; Antifolate; Chemistry; Pyrimidine; Symporter; Cell culture; In vivo; Pemetrexed; Molecular biology; In vitro; Transporter; Biochemistry; Biology; Antimetabolite; Gene; Toxicity","score_opus":0.040810511290682056,"score_gpt":0.33997229015185576,"score_spread":0.2991617788611737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157037954","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906569,0.00014008455,0.003576307,0.0009672,0.00011429981,0.0033737975,0.000026772681,0.000080140606,0.0010644606],"genre_scores_gemma":[0.9953232,0.000009651554,0.00033643728,0.0036204471,0.000050532133,0.00042107064,0.0000580569,0.00007720521,0.00010340285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99748075,0.00016310171,0.0005801877,0.0005726142,0.00045619416,0.0007471702],"domain_scores_gemma":[0.99886787,0.000059969494,0.00016789035,0.00036103599,0.00031064756,0.0002325607],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006948114,0.00035476906,0.00060103944,0.00033717323,0.00019920041,0.0000112361495,0.0003723988,0.00017555672,0.00053568004],"category_scores_gemma":[0.000032418906,0.0002534316,0.00022510714,0.0007334193,0.00022472671,0.000055375607,0.000044438784,0.0006644357,0.0000270281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022919322,0.0013906593,0.00054064597,0.00010221367,0.00048884324,0.0002639458,0.00096743606,0.00018687622,0.9930591,0.00005529997,0.0003468642,0.00030618912],"study_design_scores_gemma":[0.0054299776,0.0027345326,0.0054386244,0.00005638442,0.0003656872,0.000027603382,0.000041943582,0.01920098,0.9659033,0.000030594758,0.00051323854,0.000257168],"about_ca_topic_score_codex":0.0001782433,"about_ca_topic_score_gemma":0.0000068088298,"teacher_disagreement_score":0.02715583,"about_ca_system_score_codex":0.000076504846,"about_ca_system_score_gemma":0.00019247794,"threshold_uncertainty_score":0.9999918},"labels":[],"label_agreement":null},{"id":"W2157348568","doi":"10.1124/mol.109.056127","title":"Increased GABAB Receptor-Mediated Signaling Reduces the Susceptibility of Fragile X Knockout Mice to Audiogenic Seizures","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"FMR1; Knockout mouse; Fragile X syndrome; Allosteric modulator; Internal medicine; Agonist; Receptor; Metabotropic glutamate receptor; Endocrinology; Metabotropic receptor; Pharmacology; GABAB receptor; Metabotropic glutamate receptor 5; Chemistry; Biology; Medicine; Biochemistry; Genetics; Fragile x","score_opus":0.007462957710162643,"score_gpt":0.2617485947842784,"score_spread":0.2542856370741158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157348568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99672633,0.00086556526,0.0002258689,0.0011079214,0.00023397706,0.00048825392,0.000042025287,0.00001762306,0.0002924094],"genre_scores_gemma":[0.9936608,0.00013530097,0.00059880666,0.005284987,0.000048259677,0.000033109456,0.00014299038,0.000024350122,0.00007138612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832594,0.00027816024,0.00034143488,0.00050000433,0.0001786218,0.0003758288],"domain_scores_gemma":[0.999292,0.00003311698,0.00011897997,0.00027978682,0.0001297198,0.00014636738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027265414,0.00023125818,0.00022068771,0.00006826726,0.00010377408,0.0000115491475,0.0004443303,0.00014140694,0.00014423045],"category_scores_gemma":[0.000109291366,0.00020199096,0.00014115337,0.00024686995,0.00014455407,0.0000025709176,0.00014582308,0.00013861599,0.000027469952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021060127,0.00015270332,0.00012471176,0.000008234848,0.00008976247,0.000007660652,0.00011882841,0.0003868467,0.98943466,0.000005641533,0.008541039,0.000919283],"study_design_scores_gemma":[0.00065204815,0.00050177117,0.0042806594,0.0000052509445,0.00004058587,0.000008956991,0.00008090842,0.000024800398,0.9827375,0.000034343295,0.011412238,0.00022092761],"about_ca_topic_score_codex":0.000025003614,"about_ca_topic_score_gemma":0.000010370363,"teacher_disagreement_score":0.0066971765,"about_ca_system_score_codex":0.0000184294,"about_ca_system_score_gemma":0.00013037426,"threshold_uncertainty_score":0.8236952},"labels":[],"label_agreement":null},{"id":"W2157702102","doi":"10.1124/mol.64.6.1434","title":"Heterogeneous Role of Caspase-8 in Fenretinide-Induced Apoptosis in Epithelial Ovarian Carcinoma Cell Lines","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Cancer Institute; Université Laval","keywords":"Fenretinide; Apoptosis; Caspase 8; Programmed cell death; Ceramide; Biology; Caspase; Cancer research; Cell culture; Cell biology; DNA fragmentation; Caspase 3; Retinoid; Biochemistry; Retinoic acid","score_opus":0.007070361498279085,"score_gpt":0.24781284881302343,"score_spread":0.24074248731474435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157702102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943024,0.0020373727,0.00017234379,0.000045666344,0.00028142246,0.000325662,0.000010645105,0.000008697151,0.0028158256],"genre_scores_gemma":[0.99868435,0.00011778842,0.00056811783,0.00032518804,0.00006736575,0.0000876558,0.000036163037,0.000046855068,0.00006652308],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99788654,0.00042868254,0.0005008947,0.0005527111,0.0001423668,0.0004888036],"domain_scores_gemma":[0.9993335,0.000024411414,0.00015332797,0.0003043543,0.0000850154,0.00009940188],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003102446,0.00027594596,0.00035033873,0.00017995872,0.00003125658,0.000008861929,0.0003093932,0.00034611506,0.00008512863],"category_scores_gemma":[0.000078748955,0.00030258036,0.00013464016,0.0002766798,0.000089787354,0.0000044270187,0.000098619435,0.00023118728,0.000008273927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014307794,0.00025264014,0.0057294713,0.000059366987,0.000027553659,0.00011979623,0.00009806091,0.0009224448,0.99222255,0.000060187733,0.000034757122,0.0003301059],"study_design_scores_gemma":[0.0021796387,0.00031374287,0.0002833875,0.0000083161785,0.000033197128,0.000047639154,0.0000876133,0.0001521562,0.99473435,0.00017410683,0.0016970354,0.00028879833],"about_ca_topic_score_codex":0.00012973476,"about_ca_topic_score_gemma":0.000034575438,"teacher_disagreement_score":0.005446084,"about_ca_system_score_codex":0.00004306125,"about_ca_system_score_gemma":0.00024719036,"threshold_uncertainty_score":0.99994266},"labels":[],"label_agreement":null},{"id":"W2157843443","doi":"10.1124/mol.114.093393","title":"Superiority of Combined Phosphodiesterase PDE3/PDE4 Inhibition over PDE4 Inhibition Alone on Glucocorticoid- and Long-Acting β2-Adrenoceptor Agonist–Induced Gene Expression in Human Airway Epithelial Cells","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Rolipram; Formoterol; Phosphodiesterase 3; Phosphodiesterase; Roflumilast; Glucocorticoid; Dexamethasone; Endocrinology; Internal medicine; Pharmacology; Medicine; Chemistry; Corticosteroid; Budesonide; COPD; Enzyme; Biochemistry","score_opus":0.008689732617773446,"score_gpt":0.26028639487941707,"score_spread":0.2515966622616436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157843443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99585277,0.0000970212,0.0023923577,0.00011769365,0.00061407586,0.00074783334,0.000028270386,0.000025859048,0.00012409929],"genre_scores_gemma":[0.998253,0.000036943937,0.00016589618,0.0007814468,0.00014209385,0.00008294301,0.00040837267,0.00004630619,0.00008303631],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785227,0.00038599997,0.0005463382,0.0006417707,0.00021174733,0.0003618828],"domain_scores_gemma":[0.99916214,0.00003733448,0.00028366252,0.00028425426,0.00010209953,0.00013050875],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003194272,0.00032811868,0.00039657392,0.00015735682,0.00014688479,0.00002798185,0.00008222096,0.0003374854,0.00013360588],"category_scores_gemma":[0.000037082766,0.00034188468,0.0001209103,0.00013908949,0.00014493965,0.000023291264,0.00014725284,0.0002414057,0.0000079266365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006802227,0.0003840086,0.0024277195,0.00007965546,0.00003636615,0.00002495221,0.00011553528,0.0003702605,0.99511915,0.000024617268,0.00012897457,0.00060851267],"study_design_scores_gemma":[0.0057683997,0.0011786474,0.008341564,0.00006436071,0.000045480472,0.000007845561,0.000024197843,0.0004026836,0.9833804,0.00004004901,0.00040646177,0.00033990448],"about_ca_topic_score_codex":0.000046490444,"about_ca_topic_score_gemma":0.00003131816,"teacher_disagreement_score":0.01173877,"about_ca_system_score_codex":0.0000716158,"about_ca_system_score_gemma":0.000050273575,"threshold_uncertainty_score":0.9999033},"labels":[],"label_agreement":null},{"id":"W2158289001","doi":"10.1124/mol.106.028563","title":"Repression of Human GSTA1 by Interleukin-1β Is Mediated by Variant Hepatic Nuclear Factor-1C","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Psychological repression; Interleukin; Interleukin 1β; Factor (programming language); Immunology; Chemistry; Medicine; Psychology; Biochemistry; Computer science; Gene; Cytokine; Gene expression","score_opus":0.007952615015890107,"score_gpt":0.29195809990713084,"score_spread":0.2840054848912407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158289001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99471384,0.0011111214,0.00021034444,0.0007444183,0.0004999087,0.0005204502,0.00009787088,0.00007966911,0.0020223972],"genre_scores_gemma":[0.99651676,0.000045759654,0.00017189127,0.0025067423,0.00007382494,0.000032592558,0.0001394873,0.00006944042,0.0004434693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980879,0.00018333775,0.0005099034,0.00047613206,0.00035703537,0.00038571047],"domain_scores_gemma":[0.9991135,0.00006582005,0.00021962535,0.00032552192,0.00012101081,0.00015455141],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011357404,0.00025562427,0.00048223886,0.00011560237,0.000057087535,0.000008209345,0.0002233976,0.00023264425,0.005732793],"category_scores_gemma":[0.000038407667,0.00023977282,0.0001325292,0.00019622795,0.00019050053,0.000029999559,0.0001313296,0.00031923782,0.000040173618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016500878,0.00029865673,0.0009883281,0.00006610625,0.00012360429,0.000138393,0.00016048344,0.0000056425356,0.8367889,0.000012013278,0.16102645,0.00022644986],"study_design_scores_gemma":[0.0026589516,0.0008654406,0.0010875583,0.0000393791,0.00020906274,0.000038891878,0.000020162966,0.00043349527,0.9712714,0.000091802525,0.02307073,0.00021312894],"about_ca_topic_score_codex":0.00044714607,"about_ca_topic_score_gemma":0.0000044180433,"teacher_disagreement_score":0.13795571,"about_ca_system_score_codex":0.00017008155,"about_ca_system_score_gemma":0.00006494187,"threshold_uncertainty_score":0.9951761},"labels":[],"label_agreement":null},{"id":"W2158757667","doi":"10.1124/mol.107.036111","title":"The Phosphoinositide-Dependent Kinase-1 Inhibitor 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide (OSU-03012) Prevents Y-Box Binding Protein-1 from Inducing Epidermal Growth Factor Receptor","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Cancer Institute; Canadian Breast Cancer Research Alliance; Breast Cancer Alliance","keywords":"Chromatin immunoprecipitation; Molecular biology; Protein kinase B; Biology; Cell culture; Epidermal growth factor receptor; Growth inhibition; Cancer research; Cell growth; Phosphorylation; Receptor; Promoter; Biochemistry; Gene expression; Gene","score_opus":0.025892257351910173,"score_gpt":0.3415121767235288,"score_spread":0.3156199193716186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158757667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819034,0.0039433683,0.002118692,0.0033471123,0.00304046,0.0043779635,0.00023929012,0.0003258026,0.0007039344],"genre_scores_gemma":[0.99072355,0.0004490355,0.003069452,0.0014756734,0.0015657112,0.0006891137,0.00016141188,0.0003078588,0.0015582106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99076873,0.0010267154,0.001666408,0.0017152919,0.0020265311,0.0027963144],"domain_scores_gemma":[0.9955882,0.0010072559,0.00060402014,0.0010678129,0.0005179656,0.0012147384],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0027738197,0.00095803983,0.0012154911,0.00059700914,0.00082698243,0.00016949709,0.0011396966,0.00071638054,0.0031518769],"category_scores_gemma":[0.00093933474,0.00080689637,0.000516311,0.0010987377,0.0006842491,0.0002898889,0.000809563,0.0025202483,0.0006678876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013290906,0.0005116263,0.0044446457,0.00019968017,0.0007826856,0.0019884831,0.00047166992,0.000005555512,0.96556324,0.00005230329,0.0045193634,0.020131677],"study_design_scores_gemma":[0.0055756867,0.0007421879,0.0029838958,0.00032068757,0.000317593,0.000092859686,0.00029136994,0.00004293893,0.97705317,0.00011623032,0.011692219,0.00077117066],"about_ca_topic_score_codex":0.0009847065,"about_ca_topic_score_gemma":0.000055959477,"teacher_disagreement_score":0.019360507,"about_ca_system_score_codex":0.0017156776,"about_ca_system_score_gemma":0.0009640075,"threshold_uncertainty_score":0.99978095},"labels":[],"label_agreement":null},{"id":"W2159901882","doi":"10.1124/mol.113.091553","title":"Muscarinic Receptor Activation Increases hERG Channel Expression through Phosphorylation of Ubiquitin Ligase Nedd4-2","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"NEDD4; Ubiquitin ligase; hERG; Ubiquitin; Chemistry; Phosphorylation; Cell biology; Muscarinic acetylcholine receptor; Receptor; Biochemistry; Potassium channel; Biology; Biophysics; Gene","score_opus":0.00963684121486159,"score_gpt":0.28270318292606433,"score_spread":0.27306634171120275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159901882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99206233,0.0002499133,0.0048808777,0.0010308541,0.00029535196,0.0003943703,0.0000046357313,0.00007041425,0.0010112489],"genre_scores_gemma":[0.9956444,0.000110764566,0.00054631376,0.0029799638,0.00039476436,0.00007451989,0.00012674456,0.000028413924,0.00009414676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867415,0.0003161042,0.00028087985,0.00031603588,0.00014816786,0.00026465993],"domain_scores_gemma":[0.99923813,0.00013584124,0.00018661348,0.00021069183,0.00012663312,0.000102067585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018609021,0.00017064021,0.00038552127,0.00008595611,0.00007615998,0.0000031841023,0.00006792819,0.00019216276,0.0004142751],"category_scores_gemma":[0.00017771428,0.00016277783,0.0001686969,0.00018386869,0.00011244835,0.000089598405,0.00006176132,0.0002411411,0.000033161272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009714382,0.00019955072,0.000054048505,0.00006773097,0.00009133636,0.000029869387,0.00014257355,0.00036179862,0.99298996,0.0002309916,0.0031839025,0.0016767924],"study_design_scores_gemma":[0.0021088994,0.00059029285,0.00073452556,0.000049402395,0.00014336364,0.000042222095,0.000026205516,0.00037930353,0.9917775,0.0005106366,0.0035041438,0.00013350115],"about_ca_topic_score_codex":0.000049083887,"about_ca_topic_score_gemma":5.193513e-7,"teacher_disagreement_score":0.004334564,"about_ca_system_score_codex":0.000057097106,"about_ca_system_score_gemma":0.000083565574,"threshold_uncertainty_score":0.66378874},"labels":[],"label_agreement":null},{"id":"W2160424012","doi":"10.1124/mol.108.045682","title":"In Vivo Inhibition of Serine Protease Processing Requires a High Fractional Inhibition of Cathepsin C","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Cathepsin G; Cathepsin L1; Cathepsin C; Proteases; Neutrophil elastase; Elastase; Cathepsin O; Chemistry; Cathepsin H; Cathepsin B; Cathepsin A; Cathepsin; Biochemistry; Serine; In vivo; Molecular biology; Proteinase 3; Cathepsin S; Cathepsin L; Biology; Enzyme; Inflammation; Immunology; Myeloperoxidase","score_opus":0.010698408659530353,"score_gpt":0.2681741117872646,"score_spread":0.2574757031277342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160424012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940583,0.000401711,0.0044592945,0.00023344744,0.0001319626,0.00048730327,0.000036924706,0.000010248304,0.00018079882],"genre_scores_gemma":[0.99805856,0.00007274338,0.0009190973,0.00048394455,0.00015712694,0.00014500546,0.00007338602,0.00002445387,0.00006567944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987251,0.00014003682,0.00040814903,0.0003229021,0.00018044663,0.00022337044],"domain_scores_gemma":[0.99937546,0.0000058285204,0.00024974064,0.00014584047,0.00016123327,0.00006187638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016958997,0.00016393405,0.00022892599,0.00015208,0.000048563383,0.0000024932212,0.000073185874,0.00018488675,0.00013614586],"category_scores_gemma":[0.000036944122,0.00017823745,0.00008671365,0.00019294472,0.00012868526,0.000020862439,0.00008368107,0.00013156455,0.0000025282982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037845687,0.00037277542,0.00011093378,0.00009902567,0.000025477082,0.00013132585,0.00005238716,0.00019356063,0.9975617,0.00016024178,0.0008153986,0.00009869959],"study_design_scores_gemma":[0.0016192471,0.00045339233,0.00010118962,0.000043384833,0.000022969125,0.00008949568,0.000012896469,0.00013209332,0.99591607,0.00057080376,0.00087848405,0.00015996468],"about_ca_topic_score_codex":0.000079590805,"about_ca_topic_score_gemma":0.0000051612565,"teacher_disagreement_score":0.0040002535,"about_ca_system_score_codex":0.000029049179,"about_ca_system_score_gemma":0.00019741464,"threshold_uncertainty_score":0.7268312},"labels":[],"label_agreement":null},{"id":"W2161031758","doi":"10.1124/mol.114.093450","title":"Label-Free Monitoring of μ-Opioid Receptor–Mediated Signaling","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Quebec Rehabilitation Research Network; Université de Montréal; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Opioid; Receptor; Cell biology; Pharmacology; Biology; Biochemistry","score_opus":0.009961288683444971,"score_gpt":0.2641422670028574,"score_spread":0.25418097831941244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161031758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97531396,0.000986122,0.021761963,0.000107070766,0.0010946094,0.00018979202,0.000014043976,0.000030889223,0.00050155533],"genre_scores_gemma":[0.9904085,0.00014243842,0.008258223,0.00038007658,0.00054014346,0.00003627105,0.00007172345,0.00005135993,0.00011129246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842364,0.00023426807,0.00035121973,0.0004115832,0.0001948918,0.00038438977],"domain_scores_gemma":[0.99914503,0.000041127838,0.00017014924,0.000361096,0.00014936342,0.00013325403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041537965,0.00022000422,0.00027660196,0.000084125495,0.00007076286,0.0000115855155,0.00045452945,0.0002315705,0.0003787851],"category_scores_gemma":[0.00015235874,0.00023191674,0.00012199217,0.00014224206,0.00007822486,0.0000042974348,0.00021183617,0.00016114514,0.000023464656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081803446,0.00007277867,0.00049157423,0.00003324307,0.00011350975,0.0000042899883,0.00003624108,0.00028383802,0.9960872,0.00016652995,0.0010543666,0.001574633],"study_design_scores_gemma":[0.0013987775,0.0003981155,0.000027669923,0.000016315056,0.000041570678,0.000004920924,0.000027952578,0.0002465245,0.9771804,0.00020168167,0.020226872,0.00022915564],"about_ca_topic_score_codex":0.000009635311,"about_ca_topic_score_gemma":4.209033e-7,"teacher_disagreement_score":0.019172506,"about_ca_system_score_codex":0.000015996458,"about_ca_system_score_gemma":0.000054322845,"threshold_uncertainty_score":0.945729},"labels":[],"label_agreement":null},{"id":"W2161650611","doi":"10.1124/mol.112.081695","title":"Somatic Mutations in GRM1 in Cancer Alter Metabotropic Glutamate Receptor 1 Intracellular Localization and Signaling","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Metabotropic glutamate receptor 1; Metabotropic glutamate receptor 5; Metabotropic glutamate receptor 6; Metabotropic glutamate receptor; Metabotropic glutamate receptor 7; Biology; Cell biology; Metabotropic glutamate receptor 3; Glutamate receptor; Metabotropic glutamate receptor 4; Intracellular; Biochemistry; Receptor","score_opus":0.02981012693049601,"score_gpt":0.3416067271634724,"score_spread":0.3117966002329764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161650611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99568176,0.00026429043,0.0004993825,0.0020771844,0.00051524444,0.00087872834,0.0000042677434,0.000039039216,0.000040090385],"genre_scores_gemma":[0.9942437,0.00040755217,0.000053309053,0.00462553,0.000035243807,0.00053084607,0.0000011187743,0.000027350265,0.0000753482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99733317,0.00089148845,0.0003649444,0.0006002433,0.00022406527,0.00058610993],"domain_scores_gemma":[0.9994122,0.00022286463,0.0000821896,0.00011404556,0.00003422976,0.00013448413],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019836471,0.00018212893,0.000245029,0.00045391888,0.00011599904,0.00005910242,0.00026985566,0.000079617996,0.0012022703],"category_scores_gemma":[0.00012274127,0.00018148338,0.000032445158,0.00079417415,0.00031518287,0.00033821203,0.00013177158,0.00039740797,0.00015541077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020900137,0.00015039727,0.0017037528,0.000030720712,0.0000034557138,0.00032012787,0.00016246102,0.0044113393,0.9922092,0.0000687422,0.000081254046,0.0008376604],"study_design_scores_gemma":[0.0010821857,0.00008104559,0.0005659906,0.000010745948,0.000015306287,0.000018236968,0.000016808153,0.046410006,0.9509734,0.00038991534,0.00028160465,0.00015479134],"about_ca_topic_score_codex":0.000093791175,"about_ca_topic_score_gemma":0.000008397671,"teacher_disagreement_score":0.041998666,"about_ca_system_score_codex":0.00006659524,"about_ca_system_score_gemma":0.000078679,"threshold_uncertainty_score":0.99971074},"labels":[],"label_agreement":null},{"id":"W2161809826","doi":"10.1124/mol.108.048074","title":"Binding of Orthosteric Ligands to the Allosteric Site of the M2 Muscarinic Cholinergic Receptor","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Allosteric regulation; Oxotremorine; Chemistry; Muscarinic acetylcholine receptor; Stereochemistry; Agonist; Muscarinic acetylcholine receptor M2; Ligand (biochemistry); Antagonist; Receptor; Biochemistry","score_opus":0.0115841327389137,"score_gpt":0.25107359960490094,"score_spread":0.23948946686598724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161809826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966006,0.00055122474,0.0010134134,0.00045534977,0.00080753356,0.00035998828,0.00002286755,0.0000067873175,0.00018222957],"genre_scores_gemma":[0.99752164,0.00018555947,0.0003263295,0.0012864176,0.00016190934,0.000038939765,0.000024960416,0.000030234485,0.00042399182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870867,0.00015860716,0.0003606711,0.00030783,0.00018551163,0.00027871956],"domain_scores_gemma":[0.99919754,0.000017545697,0.000206881,0.00039131392,0.00011173752,0.000074987125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002459783,0.00017799225,0.00024056819,0.00006163394,0.00011579745,0.000004746606,0.00046355222,0.00013111596,0.00021154397],"category_scores_gemma":[0.000036705183,0.000118205826,0.00022949389,0.00033673758,0.00012070851,0.0000030058802,0.00038397755,0.00013575799,0.000015507649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008143212,0.000050065646,0.00071836595,0.000015084304,0.00008853508,0.0000049702808,0.00020498871,0.0012021817,0.9956006,0.000013863307,0.0016842757,0.00033566114],"study_design_scores_gemma":[0.00049410114,0.00030353878,0.00052602554,0.000010485388,0.000049890958,0.000036270165,0.000029963632,0.000057135363,0.980222,0.0000032959167,0.018136809,0.00013050166],"about_ca_topic_score_codex":0.000015286607,"about_ca_topic_score_gemma":0.000003706576,"teacher_disagreement_score":0.016452534,"about_ca_system_score_codex":0.000011866625,"about_ca_system_score_gemma":0.00008342493,"threshold_uncertainty_score":0.48202938},"labels":[],"label_agreement":null},{"id":"W2163772163","doi":"10.1124/mol.108.045674","title":"Identification of Regions Required for Apical Membrane Localization of Human Multidrug Resistance Protein 2","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Multidrug resistance-associated protein 2; Apical membrane; Multidrug Resistance-Associated Proteins; ATP-binding cassette transporter; Transporter; Membrane; Biology; Biochemistry; Chemistry; Cell biology; Gene","score_opus":0.021899343657761222,"score_gpt":0.31059604334594043,"score_spread":0.28869669968817924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163772163","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7294631,0.0002893374,0.2676406,0.0006171185,0.00013068778,0.0015652169,0.000021970687,0.000039854523,0.00023213732],"genre_scores_gemma":[0.9957668,0.000033241864,0.0019082905,0.000112712245,0.000038334918,0.00016076515,0.0001005771,0.000024532004,0.0018547034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988274,0.00005879722,0.00052256073,0.00023139127,0.00019482659,0.00016503078],"domain_scores_gemma":[0.99921054,0.000017034447,0.00024705916,0.00020121255,0.00025993845,0.000064237356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017398782,0.0001063813,0.0003230917,0.00011620087,0.00008411911,0.0000010106303,0.00009549272,0.00010722796,0.000034674747],"category_scores_gemma":[0.000028898878,0.000104209226,0.00013429743,0.00019625471,0.00022886865,0.00003387307,0.000008646537,0.00007349193,0.0000014127476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055623567,0.00031737649,0.000048674203,0.00062298373,0.0000773258,0.00005209278,0.00022263655,0.000070163784,0.9931067,0.0045258775,0.00037480518,0.000025076695],"study_design_scores_gemma":[0.0027343535,0.00013441558,0.0002151094,0.00007679405,0.00018805194,0.000007865013,0.000026782875,0.0006113216,0.9942622,0.0005625675,0.0010962298,0.00008429028],"about_ca_topic_score_codex":0.000004957088,"about_ca_topic_score_gemma":0.0000072375365,"teacher_disagreement_score":0.26630375,"about_ca_system_score_codex":0.000031342995,"about_ca_system_score_gemma":0.00007655106,"threshold_uncertainty_score":0.4249529},"labels":[],"label_agreement":null},{"id":"W2164124509","doi":"10.1124/mol.105.021543","title":"The Role of Human Nucleoside Transporters in Cellular Uptake of 4′-Thio-β-d-arabinofuranosylcytosine and β-d-Arabinosylcytosine","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoside; Chemistry; Nucleoside transporter; Transporter; Biochemistry; Biophysics; Biology; Gene","score_opus":0.003949996145485442,"score_gpt":0.2446082736136001,"score_spread":0.24065827746811466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164124509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990041,0.008007417,0.00022671532,0.0003062329,0.000055693676,0.00037550443,0.0000191273,0.0000074861987,0.00096083095],"genre_scores_gemma":[0.9991524,0.00026852224,0.00013343275,0.00012217855,0.00006864897,0.000038006354,0.000088635716,0.00003580401,0.00009236589],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981394,0.00015324682,0.00060098275,0.00042556794,0.00023147093,0.00044934053],"domain_scores_gemma":[0.9993027,0.000020897083,0.00015763057,0.0003185001,0.00011328878,0.00008700539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033241717,0.00023093061,0.00032047715,0.00010588273,0.000082747916,0.000010002067,0.00036273577,0.00022842344,0.000018250723],"category_scores_gemma":[0.000018054256,0.00019812482,0.00015115105,0.00022196794,0.00060632575,0.0000044391786,0.00013531688,0.00021203452,9.543563e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023244893,0.00021479033,0.001504621,0.00004701027,0.000067413755,0.000030995958,0.000019200088,0.000043132117,0.994359,0.0009630338,0.00022834788,0.0022899876],"study_design_scores_gemma":[0.0015608629,0.00032459648,0.0018694595,0.000013727239,0.000047798785,0.000011549114,0.00004413609,0.000087731925,0.9878789,0.00068722473,0.00729336,0.00018063324],"about_ca_topic_score_codex":0.00021917006,"about_ca_topic_score_gemma":0.000070088514,"teacher_disagreement_score":0.009111414,"about_ca_system_score_codex":0.000013354376,"about_ca_system_score_gemma":0.00006328292,"threshold_uncertainty_score":0.8079296},"labels":[],"label_agreement":null},{"id":"W2164442872","doi":"10.1124/mol.108.051805","title":"Calcium Signaling by Dopamine D5 Receptor and D5-D2 Receptor Hetero-Oligomers Occurs by a Mechanism Distinct from That for Dopamine D1-D2 Receptor Hetero-Oligomers","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":108,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Dopamine receptor D2; Chemistry; Dopamine; Dopamine receptor D1; Dopamine receptor; Mechanism (biology); Receptor; Calcium; Dopamine receptor D3; Biophysics; Biochemistry; Cell biology; Neuroscience; Biology; Physics; Organic chemistry","score_opus":0.028434928859643258,"score_gpt":0.302995100656125,"score_spread":0.27456017179648173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164442872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9844031,0.00065733254,0.0033068175,0.0035271165,0.0028193751,0.0025547033,0.0023072315,0.00036894187,0.000055407352],"genre_scores_gemma":[0.98467404,0.0003059179,0.0016756854,0.011137296,0.000259171,0.0009134596,0.00042934244,0.00024894852,0.000356128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9919703,0.001000249,0.0012563447,0.002791836,0.00088666973,0.0020946134],"domain_scores_gemma":[0.9971321,0.0006281883,0.00057045225,0.00069134496,0.0001140113,0.00086390245],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005060495,0.001281451,0.0013201901,0.00052283896,0.00038384713,0.00021617526,0.0013177039,0.00053417025,0.0013809219],"category_scores_gemma":[0.00020539043,0.0013786334,0.00042575347,0.0007840564,0.0005828903,0.0005944125,0.00021045149,0.001052124,0.00018031111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084170606,0.00063273037,0.00038164042,0.000052951767,0.00005165727,0.00012672214,0.00026263302,0.000018615301,0.9829658,0.00003374445,0.009766097,0.0048656776],"study_design_scores_gemma":[0.0057240967,0.0013410195,0.00005797345,0.0000677831,0.00018699293,0.00003780589,0.000070601025,0.00020939985,0.9529057,0.000086973,0.038014133,0.0012975114],"about_ca_topic_score_codex":0.00012759636,"about_ca_topic_score_gemma":0.0000048150214,"teacher_disagreement_score":0.030060114,"about_ca_system_score_codex":0.00041112266,"about_ca_system_score_gemma":0.00009262352,"threshold_uncertainty_score":0.99999374},"labels":[],"label_agreement":null},{"id":"W2165456654","doi":"10.1124/mol.108.045690","title":"(2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a Matrix Metalloprotease Inhibitor, Is a Novel and Potent Activator of Hypoxia-Inducible Factors","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Québec","funders":"National Cancer Institute","keywords":"Hydroxylation; Inducer; Hypoxia-Inducible Factor 1; Transcription factor; Hypoxia-inducible factors; Cell biology; Chemistry; Protein subunit; Activator (genetics); Biochemistry; Biology; Gene; Enzyme","score_opus":0.017342204187516124,"score_gpt":0.2702163517547168,"score_spread":0.25287414756720067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165456654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98661,0.0075989906,0.0029159908,0.00030678167,0.0013481481,0.00081368844,0.00016457346,0.000037741887,0.0002040891],"genre_scores_gemma":[0.9938852,0.001329667,0.0017673143,0.001095308,0.00075372524,0.0001304089,0.00010557263,0.000091338545,0.0008414199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99725795,0.0001476601,0.00057593663,0.00097188796,0.00037666946,0.0006699195],"domain_scores_gemma":[0.9985288,0.000026623931,0.00031401322,0.0005402947,0.00021145365,0.00037881834],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020882118,0.0005245336,0.0006587428,0.00021165915,0.00018906436,0.000016372953,0.0003589996,0.00040270056,0.00012312838],"category_scores_gemma":[0.00008519596,0.00051310385,0.0003411851,0.0002797606,0.00043748756,0.000021539878,0.00037477427,0.00031335978,0.000008072148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002947446,0.00041847638,0.00045642964,0.00007314475,0.0004431277,0.000026465248,0.00024185271,0.000057718913,0.9937921,0.00006657906,0.003451562,0.00067779946],"study_design_scores_gemma":[0.003146475,0.00034240005,0.002094845,0.000011611015,0.00024478926,0.00017517061,0.00006633286,0.000087964625,0.89740705,0.000049363483,0.09588416,0.0004898093],"about_ca_topic_score_codex":0.00018102763,"about_ca_topic_score_gemma":0.00000573771,"teacher_disagreement_score":0.09638502,"about_ca_system_score_codex":0.000044799177,"about_ca_system_score_gemma":0.00036767984,"threshold_uncertainty_score":0.9997321},"labels":[],"label_agreement":null},{"id":"W2165609870","doi":"10.1124/mol.105.017376","title":"Transcriptional Regulation of the Human NRIP1/RIP140 Gene by Estrogen Is Modulated by Dioxin Signalling","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Chromatin immunoprecipitation; Aryl hydrocarbon receptor; Exon; Estrogen receptor; Transcriptional regulation; Nuclear receptor; Cell biology; RNA splicing; Chemistry; Transcription (linguistics); Gene; Molecular biology; Biology; Transcription factor; Gene expression; Promoter; RNA; Genetics; Biochemistry","score_opus":0.0035159497094464317,"score_gpt":0.2268789611515531,"score_spread":0.22336301144210666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165609870","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98964953,0.005988575,0.0031058216,0.0003286367,0.00017698025,0.00034936424,0.00009248919,0.000018447752,0.0002901227],"genre_scores_gemma":[0.9976752,0.00005184729,0.00014198927,0.0005196498,0.00010405046,0.000030521565,0.0006773122,0.000039753242,0.0007596979],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998541,0.00021341487,0.00033840153,0.00038739134,0.00021037982,0.00030940567],"domain_scores_gemma":[0.99947315,0.0000071640425,0.00015954641,0.00021319493,0.00008393682,0.0000630264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013302005,0.00022122377,0.00019033204,0.0000406409,0.0001406429,0.000010267223,0.00027778288,0.0003258781,0.0000951696],"category_scores_gemma":[0.000003873439,0.00019292088,0.00022361391,0.00016076564,0.00016838271,0.000004841867,0.000058111476,0.00017492705,0.0000053212666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050159822,0.00016686709,0.00032835567,0.000011009475,0.00019118439,0.0000039238253,0.000011635024,0.0016876472,0.97332597,0.000115565155,0.02400837,0.00009929949],"study_design_scores_gemma":[0.0012340808,0.00014494252,0.00048900733,0.0000051154198,0.00013617334,0.000019031137,0.0000021956967,0.0006591601,0.98882556,0.00018374153,0.008105778,0.00019523049],"about_ca_topic_score_codex":0.000053148786,"about_ca_topic_score_gemma":7.126584e-7,"teacher_disagreement_score":0.01590259,"about_ca_system_score_codex":0.000025831494,"about_ca_system_score_gemma":0.000044467295,"threshold_uncertainty_score":0.7867085},"labels":[],"label_agreement":null},{"id":"W2165665524","doi":"10.1124/mol.114.093104","title":"Fluoxetine Blocks Nav1.5 Channels via a Mechanism Similar to That of Class 1 Antiarrhythmics","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"National Institute of Neurological Disorders and Stroke; Natural Sciences and Engineering Research Council of Canada; Heart And Stroke Foundation Of Quebec; University at Buffalo; National Institutes of Health; Canadian Institutes of Health Research; Northeastern States Research Cooperative; Heart and Stroke Foundation of Canada","keywords":"Fluoxetine; Chemistry; Stereochemistry; Metabolite; Patch clamp; Reuptake inhibitor; Serotonin; Receptor; Biochemistry","score_opus":0.009205775906459332,"score_gpt":0.25582321056803475,"score_spread":0.24661743466157543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165665524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.63662475,0.00008565547,0.35903934,0.0012683495,0.002031362,0.00034482445,0.000011626356,0.000028101238,0.0005659931],"genre_scores_gemma":[0.9939831,0.000034897206,0.00076739106,0.0037520812,0.0007569518,0.00004943541,0.00011555796,0.000042784686,0.00049782114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998565,0.00018009669,0.00026973768,0.00045042456,0.00018997201,0.00034475993],"domain_scores_gemma":[0.99923176,0.00001857914,0.00013190886,0.00027001783,0.00017707612,0.00017068673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031711604,0.00022666914,0.0002584242,0.00013887501,0.00006859587,0.00000944066,0.00019776556,0.00025906225,0.00015881583],"category_scores_gemma":[0.00006281689,0.00023872902,0.00014447319,0.00016464012,0.00006201899,0.0000038798785,0.000164263,0.000114057584,0.000026399763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018728826,0.00007033784,0.000030008756,0.000019163992,0.00008220269,0.000010685457,0.000041397594,0.006738881,0.9882358,0.00040017048,0.0028614684,0.0013226479],"study_design_scores_gemma":[0.00099122,0.00053842354,0.000022267099,0.0000051393163,0.00004683244,0.000050192648,0.0000132201,0.013206247,0.9182602,0.0002752475,0.066366,0.00022500908],"about_ca_topic_score_codex":0.000005346797,"about_ca_topic_score_gemma":0.000001379746,"teacher_disagreement_score":0.35827196,"about_ca_system_score_codex":0.000015990267,"about_ca_system_score_gemma":0.000034506193,"threshold_uncertainty_score":0.97350866},"labels":[],"label_agreement":null},{"id":"W2166930152","doi":"10.1124/mol.108.045054","title":"Mutational Analysis of the Conserved Asp2.50 and ERY Motif Reveals Signaling Bias of the Urotensin II Receptor","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Mutant; Receptor; Biology; Molecular biology; Biochemistry; Gene","score_opus":0.05163250688141303,"score_gpt":0.30996218869285774,"score_spread":0.2583296818114447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166930152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966353,0.0012758796,0.00015171025,0.0010093716,0.00011976996,0.00048021533,0.000045311535,0.000008098781,0.0002743255],"genre_scores_gemma":[0.9982167,0.0001677932,0.00018002569,0.00097207713,0.000042708532,0.000014363638,0.000015230901,0.00001653883,0.00037455666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99768233,0.00096797815,0.0003689497,0.00026745076,0.0005091225,0.00020418274],"domain_scores_gemma":[0.998747,0.00026298736,0.00018037601,0.0003238056,0.00040738453,0.00007842855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004454425,0.00013224604,0.0005250392,0.00020265668,0.0001669901,0.0000034431066,0.00017480728,0.00006721535,0.00034075568],"category_scores_gemma":[0.0004261777,0.000084637904,0.000574365,0.0008776086,0.000747968,0.000021871345,0.00022675452,0.00026604376,0.000002054697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015635818,0.0000933292,0.019343454,0.0000488453,0.0029671253,0.00008357406,0.00023565695,0.0011989066,0.97435856,0.00002027587,0.0013010664,0.0001928252],"study_design_scores_gemma":[0.001450477,0.00010164818,0.19895214,0.000031068732,0.0020481788,0.000104604136,0.000041428015,0.0005433977,0.7954151,0.000015593097,0.0012184782,0.000077866345],"about_ca_topic_score_codex":0.00007141276,"about_ca_topic_score_gemma":0.000003670661,"teacher_disagreement_score":0.17960867,"about_ca_system_score_codex":0.000026515836,"about_ca_system_score_gemma":0.0001684791,"threshold_uncertainty_score":0.3731036},"labels":[],"label_agreement":null},{"id":"W2167203320","doi":"10.1124/mol.110.069674","title":"Evidence for a Second Receptor for Prostacyclin on Human Airway Epithelial Cells That Mediates Inhibition of CXCL9 and CXCL10 Release","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Iloprost; Pharmacology; Receptor; Prostacyclin; Chemistry; Receptor antagonist; Cell biology; Antagonist; Biology; Biochemistry","score_opus":0.04202714580207631,"score_gpt":0.35201071557718705,"score_spread":0.30998356977511077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167203320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955016,0.00021751823,0.00062830106,0.0011113037,0.00058330654,0.0017749785,0.00010752556,0.000027007369,0.000048493366],"genre_scores_gemma":[0.99622595,0.00005110635,0.0016580836,0.0009626713,0.00046908847,0.00029438525,0.00008134195,0.00004076841,0.00021662659],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998892,0.00004789777,0.0002978129,0.000357521,0.00013794926,0.00026682473],"domain_scores_gemma":[0.9990003,0.00038293435,0.00017281124,0.00013469906,0.0001546931,0.00015454984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039730853,0.00017768057,0.00036331508,0.00011450987,0.000081288825,0.000009230463,0.000060590548,0.00018034788,0.0006188968],"category_scores_gemma":[0.00017419482,0.00016055528,0.00014989707,0.00006481534,0.00013681463,0.000052283056,0.0000332483,0.0002566057,0.0000040438745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010834788,0.0001867141,0.0001749257,0.00045698078,0.00005956221,0.00000801348,0.0001556588,0.0000025448956,0.9919216,0.00011141343,0.004104463,0.0017346237],"study_design_scores_gemma":[0.0046647475,0.0012504078,0.000062268206,0.00010364902,0.00020502342,0.000007946369,0.000019611613,0.00022100516,0.9871642,0.00022751854,0.0059238975,0.00014973317],"about_ca_topic_score_codex":0.000005778687,"about_ca_topic_score_gemma":0.000005234734,"teacher_disagreement_score":0.0047574295,"about_ca_system_score_codex":0.000026195992,"about_ca_system_score_gemma":0.000075215816,"threshold_uncertainty_score":0.6776486},"labels":[],"label_agreement":null},{"id":"W2167458439","doi":"10.1124/mol.104.004408","title":"Role of Human Nucleoside Transporters in the Cellular Uptake of Two Inhibitors of IMP Dehydrogenase, Tiazofurin and Benzamide Riboside","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoside; Nucleoside transporter; Uridine; Cytotoxicity; Biochemistry; Biology; Thymidine; Transporter; In vitro; RNA","score_opus":0.0073497419433682775,"score_gpt":0.2739029985109642,"score_spread":0.26655325656759593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167458439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974578,0.0010592998,0.00003368424,0.0004639351,0.000031295935,0.00054587016,0.000010413125,0.000008950999,0.0003887548],"genre_scores_gemma":[0.999178,0.000045277186,0.0004704121,0.00018731791,0.000018425295,0.000029182944,0.000030979692,0.000020379808,0.000020052574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987255,0.000073863004,0.00055352837,0.0002112313,0.00021213756,0.0002237883],"domain_scores_gemma":[0.9995373,0.000025257714,0.00016199892,0.00016305859,0.00004125815,0.0000711267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023792747,0.0001695115,0.0004256576,0.00020511492,0.000025596997,0.0000015532237,0.0001096028,0.00006854038,0.000041811658],"category_scores_gemma":[0.000004675898,0.00013507898,0.00012135908,0.00022427639,0.0001908237,0.000027052618,0.00002344493,0.00013653767,0.0000013765958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009844075,0.0005656638,0.015448342,0.00009319107,0.00023780784,0.00036193995,0.002503155,0.00015292542,0.9797019,0.00042464997,0.000030668205,0.00038136737],"study_design_scores_gemma":[0.005997404,0.0002329242,0.008132786,0.00006197851,0.00040158766,0.000021218724,0.0004081872,0.000021680722,0.98402685,0.00046244555,0.00014032904,0.000092595066],"about_ca_topic_score_codex":0.0001548934,"about_ca_topic_score_gemma":0.00006818213,"teacher_disagreement_score":0.0073155565,"about_ca_system_score_codex":0.00004020713,"about_ca_system_score_gemma":0.00009469354,"threshold_uncertainty_score":0.5508361},"labels":[],"label_agreement":null},{"id":"W2167458726","doi":"10.1124/mol.66.4.921","title":"Raf Kinase Activation of Adenylyl Cyclases: Isoform-Selective Regulation","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Adenylyl cyclase; ADCY10; ADCY9; ADCY6; Gs alpha subunit; ADCY3; cAMP-dependent pathway; Biochemistry; Protein kinase A; Biology; Chemistry; Cell biology; Kinase; Signal transduction","score_opus":0.007921842875711498,"score_gpt":0.2682030033215912,"score_spread":0.2602811604458797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167458726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89565206,0.00037076557,0.102375105,0.00032915873,0.00012530078,0.000444477,0.000009190689,0.000021332944,0.0006726004],"genre_scores_gemma":[0.9973361,0.000025580253,0.0015194869,0.0006224046,0.00014898732,0.0000632367,0.00018305724,0.0000288135,0.00007234704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988385,0.00010753906,0.00028776645,0.00034917626,0.00016673582,0.00025028494],"domain_scores_gemma":[0.9993257,0.000009029114,0.00018935287,0.00020401686,0.00018862024,0.000083294566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001600736,0.00017819717,0.00017817842,0.00012589293,0.0000788222,0.000008203102,0.0001354368,0.00019878175,0.00007871192],"category_scores_gemma":[0.000059662052,0.00019392687,0.00012406839,0.00021921459,0.00010922009,0.000011161312,0.000068676716,0.000109220404,0.000009613284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000254207,0.00012703579,0.000038407674,0.00002455665,0.0000813907,0.00000827523,0.000049199756,0.01450837,0.98263955,0.0009856177,0.00028057964,0.0010027809],"study_design_scores_gemma":[0.0021107448,0.00028029465,0.00068294664,0.000018569308,0.00004656774,0.000015463582,0.000020206944,0.00023796389,0.992261,0.0013704972,0.0027627724,0.00019297283],"about_ca_topic_score_codex":0.000023309376,"about_ca_topic_score_gemma":0.000002949832,"teacher_disagreement_score":0.10168401,"about_ca_system_score_codex":0.00006286349,"about_ca_system_score_gemma":0.00016430461,"threshold_uncertainty_score":0.7908108},"labels":[],"label_agreement":null},{"id":"W2167680876","doi":"10.1124/mol.110.064642","title":"Negative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic Responses","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Center for Research Resources; National Cancer Institute; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"Gene knockdown; EIF4E; Cytarabine; Phosphorylation; Kinase; Biology; Cancer research; Small interfering RNA; Clonogenic assay; Haematopoiesis; Cell biology; Myeloid leukemia; Translation (biology); Apoptosis; Messenger RNA; RNA; Stem cell; Biochemistry; Gene","score_opus":0.011681853122985246,"score_gpt":0.3013255913230593,"score_spread":0.28964373820007405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167680876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979811,0.0005566394,0.00020455796,0.0001842305,0.0005473082,0.00041458214,0.0000073849164,0.000005959668,0.00009828704],"genre_scores_gemma":[0.9982232,0.000047951115,0.00031616903,0.0010230694,0.0002527211,0.000073520685,0.000014982643,0.000024406772,0.000024004696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867773,0.00041259598,0.00026893834,0.00028682593,0.00015521079,0.00019870415],"domain_scores_gemma":[0.99922305,0.000108009095,0.00018964973,0.00034035975,0.00010778175,0.00003115521],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036342596,0.00015657203,0.00020892142,0.00009240677,0.000030025229,0.0000045768006,0.00032094624,0.00020321141,0.000029671832],"category_scores_gemma":[0.00017017541,0.00013562209,0.00009598103,0.00015957133,0.00024376354,0.0000040683344,0.000047878875,0.00020354187,0.0000010703463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002836867,0.00011764258,0.0003035275,0.000042278236,0.000074925,0.000019857656,0.00019013273,0.000071417184,0.99704236,0.00006262885,0.0009785254,0.00081301],"study_design_scores_gemma":[0.0014646807,0.0004460926,0.003189035,0.00001084842,0.0000413032,0.000012339581,0.000015467635,0.000108850036,0.99381995,0.00005446709,0.000711634,0.00012533284],"about_ca_topic_score_codex":0.00003447393,"about_ca_topic_score_gemma":0.000022368129,"teacher_disagreement_score":0.0032224192,"about_ca_system_score_codex":0.000016711823,"about_ca_system_score_gemma":0.00018330071,"threshold_uncertainty_score":0.5530508},"labels":[],"label_agreement":null},{"id":"W2167907964","doi":"10.1124/mol.110.065078","title":"Aryl Hydrocarbon Receptor Is a Transcriptional Activator of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Abcg2; Aryl hydrocarbon receptor; Activator (genetics); Breast cancer; Chemistry; Aryl hydrocarbon receptor nuclear translocator; Receptor; Pharmacology; Cancer research; Biochemistry; Biology; Cancer; Transporter; ATP-binding cassette transporter; Transcription factor; Gene; Genetics","score_opus":0.0069999575717962425,"score_gpt":0.27137287904766805,"score_spread":0.2643729214758718,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167907964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848962,0.00024817785,0.000109636196,0.011645702,0.0008770544,0.0009029936,0.00013359767,0.000042760697,0.0011439109],"genre_scores_gemma":[0.99425226,0.000015641695,0.00032609561,0.0018291083,0.00025473448,0.00022464783,0.000015375674,0.000043783424,0.0030383742],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985405,0.000047566456,0.00031718463,0.00035810668,0.0003777805,0.00035886624],"domain_scores_gemma":[0.99927646,0.000008112976,0.00014440976,0.00030390528,0.000118364675,0.00014875803],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015718972,0.00021383238,0.0003364924,0.00007481786,0.00012358458,0.0000051871634,0.00025946595,0.00019037006,0.002708776],"category_scores_gemma":[0.0000040250143,0.00015815941,0.00024443006,0.00025069216,0.0002686461,0.000042604894,0.000020091506,0.0005961619,0.000007316744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047761825,0.0002722836,0.00085795746,0.00016237558,0.00017841533,0.00003416538,0.00017672923,0.0000013237974,0.99421424,0.0019386315,0.0015450927,0.0001411825],"study_design_scores_gemma":[0.002115156,0.000041693373,0.010932696,0.000098736746,0.00022602247,0.000017800598,0.00001604225,0.000010868631,0.9632496,0.00036398953,0.022767369,0.00015999337],"about_ca_topic_score_codex":0.000045742407,"about_ca_topic_score_gemma":0.00009238931,"teacher_disagreement_score":0.030964592,"about_ca_system_score_codex":0.00005673012,"about_ca_system_score_gemma":0.0002595761,"threshold_uncertainty_score":0.99820286},"labels":[],"label_agreement":null},{"id":"W2168245434","doi":"10.1124/mol.63.1.2","title":"Tonically Activated GABAA Receptors in Hippocampal Neurons Are High-Affinity, Low-Conductance Sensors for Extracellular GABA","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":172,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's College Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"GABAA receptor; Inhibitory postsynaptic potential; Neuroscience; Hippocampal formation; Tonic (physiology); Chemistry; Dentate gyrus; Bicuculline; Receptor; Biophysics; Biology; Biochemistry","score_opus":0.045343420143848207,"score_gpt":0.33967869412006074,"score_spread":0.2943352739762125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168245434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922972,0.00010281943,0.00012637171,0.0022942377,0.0029346552,0.0016851928,0.000047406756,0.00016145506,0.00035069193],"genre_scores_gemma":[0.9923581,0.00021888662,0.00013157274,0.005722378,0.000081567676,0.00038190384,0.0000028973502,0.000103629834,0.0009990834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99319035,0.0023467513,0.0006381085,0.0016695026,0.0005153217,0.0016399405],"domain_scores_gemma":[0.99749583,0.001250251,0.00026795908,0.00044361036,0.000120568686,0.0004217665],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006900266,0.0004989093,0.00058368983,0.0003961721,0.00036840496,0.00007246728,0.0009700073,0.0002610482,0.00079141185],"category_scores_gemma":[0.001900075,0.0005293338,0.00021293396,0.0014557826,0.00074596674,0.00030862674,0.0001984321,0.0012222452,0.0001651837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039584213,0.00070162135,0.00025495418,0.000039992967,0.000010776837,0.0024855756,0.000048981783,0.0009591362,0.99210566,0.000985457,0.0018841482,0.00012786896],"study_design_scores_gemma":[0.0033277366,0.000404315,0.0001883328,0.00001210298,0.00003243023,0.0001576519,0.000023111765,0.0004813351,0.9823562,0.0004903917,0.012066889,0.0004595206],"about_ca_topic_score_codex":0.000004490315,"about_ca_topic_score_gemma":0.0000038011167,"teacher_disagreement_score":0.01018274,"about_ca_system_score_codex":0.00013370252,"about_ca_system_score_gemma":0.00032904392,"threshold_uncertainty_score":0.9997158},"labels":[],"label_agreement":null},{"id":"W2169279691","doi":"10.1016/s0026-895x(24)23209-0","title":"Molecular Determinant of High-Affinity Dofetilide Binding to HERG1 Expressed in Xenopus Oocytes: Involvement of S6 Sites","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":251,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Dofetilide; Quinidine; hERG; Chemistry; Allosteric regulation; Mutation; Xenopus; Biochemistry; Pharmacology; Biophysics; Biology; Internal medicine; Potassium channel; Receptor; Medicine; QT interval","score_opus":0.01044684034950867,"score_gpt":0.2872314694531248,"score_spread":0.2767846291036161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169279691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997807,0.0005512753,0.00008029833,0.00045487538,0.00012889948,0.00067183806,0.0000216159,0.000025787374,0.00025837903],"genre_scores_gemma":[0.9971408,0.00013969127,0.0006725491,0.0017694194,0.000048402268,0.00009312748,0.000034004304,0.000031365133,0.000070645714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981071,0.0002715041,0.00053756323,0.00041783586,0.00020352412,0.0004624808],"domain_scores_gemma":[0.99923074,0.00009168677,0.00012276584,0.0003209977,0.00008504154,0.00014875768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002147283,0.0002355279,0.0007559959,0.0003044061,0.000030295296,0.000002504743,0.00015485343,0.00016320868,0.0005833888],"category_scores_gemma":[0.000045740835,0.00023449335,0.00020044344,0.0004355092,0.00013806691,0.000041382293,0.00008624575,0.0002731894,0.00003293595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014384942,0.00037609326,0.00049766566,0.0001344199,0.00017966008,0.0022096378,0.00021429021,0.0032512739,0.9887286,0.00006502292,0.00019285962,0.0027119801],"study_design_scores_gemma":[0.0029686287,0.0009955874,0.0025311515,0.00007874262,0.00019164843,0.0000528087,0.000030412302,0.00013459836,0.99220586,0.00010099347,0.0005286108,0.00018093163],"about_ca_topic_score_codex":0.0000985191,"about_ca_topic_score_gemma":0.0000073127812,"teacher_disagreement_score":0.0034772835,"about_ca_system_score_codex":0.00008543461,"about_ca_system_score_gemma":0.00011548202,"threshold_uncertainty_score":0.95623606},"labels":[],"label_agreement":null},{"id":"W2171093150","doi":"10.1124/mol.109.061804","title":"Functional Characterization of Vasopressin Type 2 Receptor Substitutions (R137H/C/L) Leading to Nephrogenic Diabetes Insipidus and Nephrogenic Syndrome of Inappropriate Antidiuresis: Implications for Treatments","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Institutes of Health; Kidney Foundation of Canada","keywords":"Nephrogenic diabetes insipidus; Vasopressin; Endocrinology; Endocytosis; Internal medicine; Internalization; Vasopressin receptor; Arginine vasopressin receptor 2; Chemistry; Receptor; Biology; Medicine; Antagonist","score_opus":0.011737122806952868,"score_gpt":0.2610137286777995,"score_spread":0.2492766058708466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171093150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942974,0.00016787017,0.0041864933,0.00027244343,0.00037949113,0.0005423318,0.0001335978,0.000010719502,0.000009684114],"genre_scores_gemma":[0.9975629,0.00005962953,0.0007268347,0.00014763634,0.000081194776,0.0001534418,0.001184632,0.000021535176,0.000062213665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991971,0.000034039338,0.0002581542,0.00026794974,0.00006180196,0.00018095775],"domain_scores_gemma":[0.9993999,0.000010135412,0.00013790997,0.00016306486,0.00021488301,0.00007408757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009160316,0.00013416153,0.00018761135,0.00010612483,0.00008626904,0.000005699101,0.00009273348,0.00016185587,0.00002841967],"category_scores_gemma":[0.000017952685,0.00014124297,0.00008355262,0.00017520243,0.00010303589,0.000010062134,0.000031848518,0.00005793638,0.0000023683479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000111969246,0.00011519054,0.005180788,0.000037127815,0.0002272539,2.905814e-7,0.000025805117,0.000058157442,0.99332947,0.00031860356,0.000095754185,0.00049957214],"study_design_scores_gemma":[0.0007259568,0.00026663925,0.06676039,0.0000067563064,0.0001822305,0.000008389798,0.0000046718856,0.000030823234,0.92961496,0.00006912547,0.0022122536,0.00011779315],"about_ca_topic_score_codex":0.0000024646001,"about_ca_topic_score_gemma":0.0000032081118,"teacher_disagreement_score":0.06371452,"about_ca_system_score_codex":0.000009068922,"about_ca_system_score_gemma":0.00007862316,"threshold_uncertainty_score":0.57597214},"labels":[],"label_agreement":null},{"id":"W2172081236","doi":"10.1124/mol.106.023911","title":"Overcoming Trastuzumab Resistance in HER2-Overexpressing Breast Cancer Cells by Using a Novel Celecoxib-Derived Phosphoinositide-Dependent Kinase-1 Inhibitor","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of British Columbia","funders":"National Cancer Institute","keywords":"Trastuzumab; SKBR3; Protein kinase B; PI3K/AKT/mTOR pathway; Cancer research; Medicine; Apoptosis; Growth inhibition; Breast cancer; Pharmacology; Chemistry; Cancer; Internal medicine; Biochemistry","score_opus":0.01630541155249776,"score_gpt":0.32560526798965805,"score_spread":0.3092998564371603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2172081236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98867714,0.0047408664,0.0022598214,0.0012523691,0.00057936873,0.0010520378,0.00026003137,0.00008449635,0.0010938507],"genre_scores_gemma":[0.9947425,0.00011397696,0.0024301014,0.0015700758,0.00038736296,0.00018511128,0.000028872046,0.0001410681,0.0004009406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963359,0.00024647344,0.0006595986,0.0008849148,0.0007210701,0.0011520089],"domain_scores_gemma":[0.99895924,0.000078899946,0.00019257725,0.00033132298,0.00017351701,0.00026443574],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00035761055,0.00042501296,0.0006544436,0.0002686602,0.00014761118,0.00006123131,0.00027405005,0.00026661987,0.0012309315],"category_scores_gemma":[0.000015108128,0.00047858304,0.0001528903,0.0005157824,0.00021688893,0.00013661083,0.00016634111,0.00085444044,0.000016979851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008633957,0.0006896363,0.0012100207,0.00024533743,0.0000803111,0.0010371922,0.00011473781,0.0007473813,0.9838751,0.000011619735,0.010551908,0.0005733482],"study_design_scores_gemma":[0.0068159546,0.00007506755,0.0019840256,0.00042651038,0.00013279711,0.000113199145,0.000045685832,0.0019220364,0.983297,0.000024971281,0.004729284,0.00043350516],"about_ca_topic_score_codex":0.004797642,"about_ca_topic_score_gemma":0.00042767535,"teacher_disagreement_score":0.006065333,"about_ca_system_score_codex":0.002209206,"about_ca_system_score_gemma":0.00072648644,"threshold_uncertainty_score":0.9997666},"labels":[],"label_agreement":null},{"id":"W2172197317","doi":"10.1124/mol.106.024323","title":"Inhibition of Ca2+ Influx Is Required for Mitochondrial Reactive Oxygen Species-Induced Endoplasmic Reticulum Ca2+ Depletion and Cell Death in Leukemia Cells","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"","keywords":"Endoplasmic reticulum; Thapsigargin; Programmed cell death; Antimycin A; Mitochondrion; Chemistry; Oligomycin; Unfolded protein response; Reactive oxygen species; Biochemistry; Molecular biology; Apoptosis; Biology; ATPase","score_opus":0.008981757794595546,"score_gpt":0.24791573208715184,"score_spread":0.2389339742925563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2172197317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99584675,0.0003550559,0.001018688,0.000107698885,0.00033597488,0.0008922655,0.00018155373,0.000012536046,0.0012494924],"genre_scores_gemma":[0.9976259,0.000116667885,0.00081411767,0.00038399463,0.0002409733,0.00018090672,0.00040813122,0.000040961422,0.00018835407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982225,0.0001507609,0.00045626104,0.00060728414,0.0001529444,0.00041026506],"domain_scores_gemma":[0.99924695,0.000040846346,0.00023279918,0.00023103454,0.00013601597,0.00011233058],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010589407,0.00027740502,0.00032432526,0.00013468413,0.00006548978,0.00001669613,0.00011843171,0.00029279702,0.000027381097],"category_scores_gemma":[0.00003307804,0.00030239846,0.00015517088,0.00011408747,0.00011341482,0.000011544415,0.00010150465,0.0001343458,0.0000027446831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006470764,0.00015856647,0.00090899825,0.00009198333,0.000040263043,0.000053964606,0.00005281517,0.00027782173,0.9947178,0.00009558163,0.0029147237,0.000040404884],"study_design_scores_gemma":[0.005198704,0.00040952707,0.0013745173,0.000018487512,0.00012596919,0.0000138855985,0.0000473877,0.00045930047,0.98960763,0.00022486209,0.002232331,0.00028742375],"about_ca_topic_score_codex":0.00027100372,"about_ca_topic_score_gemma":0.000055515306,"teacher_disagreement_score":0.005110197,"about_ca_system_score_codex":0.0000870108,"about_ca_system_score_gemma":0.00018995022,"threshold_uncertainty_score":0.99994284},"labels":[],"label_agreement":null},{"id":"W2172216633","doi":"10.1124/mol.115.098160","title":"The ClC-7 Chloride Channel Is Downregulated by Hypoosmotic Stress in Human Chondrocytes","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"DIDS; Chemistry; Chloride channel; Hyperpolarization (physics); Extracellular; Intracellular; Gene knockdown; Chondrocyte; Membrane potential; Biophysics; Biochemistry; Membrane; Biology; Stereochemistry; In vitro; Apoptosis; Nuclear magnetic resonance spectroscopy","score_opus":0.014599540705111056,"score_gpt":0.2796543466444922,"score_spread":0.26505480593938113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2172216633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931285,0.0014950058,0.00095258345,0.0017502923,0.0014575436,0.00036024436,0.000025073212,0.000030300542,0.0008004625],"genre_scores_gemma":[0.9951856,0.00009196076,0.0000110564015,0.0015905807,0.0003753409,0.00007832431,0.00032381224,0.00003277391,0.0023105482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854827,0.00017259714,0.00028644517,0.0004008292,0.00018421203,0.00040765485],"domain_scores_gemma":[0.9993389,0.000016930306,0.0000999964,0.00025094402,0.00013515391,0.00015804631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002768841,0.00020872251,0.00016032078,0.0000747578,0.0001473827,0.00003271056,0.00026770125,0.00021472089,0.00003935661],"category_scores_gemma":[0.00005053453,0.00017889068,0.000081856546,0.00019074438,0.00013693846,0.0000066107855,0.000117937314,0.00016460646,0.000024140576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023131883,0.00011201072,0.00019381083,0.000006547143,0.000069468166,0.00001661165,0.00009689223,0.0018403349,0.93782336,0.000058565845,0.05923819,0.00031287616],"study_design_scores_gemma":[0.001950348,0.00021208756,0.0001683447,0.000003675279,0.00002143017,0.000015630581,0.00010045076,0.0018650743,0.9222019,0.00020537121,0.07305209,0.00020362348],"about_ca_topic_score_codex":0.00003655724,"about_ca_topic_score_gemma":0.000014474496,"teacher_disagreement_score":0.015621503,"about_ca_system_score_codex":0.00005453906,"about_ca_system_score_gemma":0.00006548421,"threshold_uncertainty_score":0.729495},"labels":[],"label_agreement":null},{"id":"W2181502233","doi":"10.1124/mol.58.4.756","title":"Characterization of the Interaction of Zopiclone with γ-Aminobutyric Acid Type A Receptors","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Flunitrazepam; Zopiclone; Receptor; Chemistry; GABAA receptor; Protein subunit; Photoaffinity labeling; Ligand (biochemistry); Biochemistry; Pharmacology; Stereochemistry; Hypnotic; Biology","score_opus":0.025646814799862604,"score_gpt":0.31975232095754996,"score_spread":0.2941055061576874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2181502233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99787194,0.00000950128,0.000025647372,0.00053846225,0.0006984459,0.00035764012,0.0000059607064,0.00001984729,0.00047258078],"genre_scores_gemma":[0.99780273,0.00013432057,0.0000072095004,0.0014172284,0.000026401645,0.000019494875,8.4579244e-7,0.000015413818,0.0005763772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984591,0.00049669197,0.00022076364,0.00031150054,0.0002691475,0.0002427658],"domain_scores_gemma":[0.99948484,0.00006744511,0.00014284537,0.00018487922,0.00006911162,0.00005085954],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000969224,0.000112712754,0.00016615393,0.00010879985,0.00008541118,0.000006593921,0.0004117251,0.00004740526,0.0013185955],"category_scores_gemma":[0.00004992962,0.00007942667,0.000049757215,0.00096358877,0.0004416718,0.00012734716,0.00007131312,0.00024412223,0.000034203633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041418333,0.0001636388,0.00038287297,0.000015281836,0.000006811246,0.00003307235,0.00007078792,0.000084488325,0.9964539,0.000025786194,0.00006497457,0.0022842176],"study_design_scores_gemma":[0.0005631655,0.00041196425,0.0006829518,0.0000069407442,0.000028199436,0.00006050912,0.0000035597848,0.00032062022,0.9944557,0.000005090019,0.0033925863,0.00006871286],"about_ca_topic_score_codex":0.0000035040207,"about_ca_topic_score_gemma":3.0112665e-7,"teacher_disagreement_score":0.0033276116,"about_ca_system_score_codex":0.00001787295,"about_ca_system_score_gemma":0.000078814155,"threshold_uncertainty_score":0.99959433},"labels":[],"label_agreement":null},{"id":"W2182302719","doi":"10.1016/s0026-895x(24)05619-0","title":"Agonist-Induced Internalization of Leukotriene B4 Receptor 1 Requires G-Protein-Coupled Receptor Kinase 2 but Not Arrestins","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Internalization; Beta adrenergic receptor kinase; G protein-coupled receptor; G protein-coupled receptor kinase; Cell biology; Receptor; HEK 293 cells; Leukotriene B4; Biology; Agonist; Leukotriene receptor; Chemistry; Signal transduction; Biochemistry; Inflammation; Immunology; Antagonist","score_opus":0.014698202094454738,"score_gpt":0.27337789392726364,"score_spread":0.2586796918328089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2182302719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93147975,0.00039011493,0.06593278,0.00033732696,0.00093305105,0.00072341226,0.00003724244,0.000041718955,0.00012460405],"genre_scores_gemma":[0.99401224,0.0001117308,0.003891837,0.000830561,0.00041521539,0.00017912213,0.00027355104,0.000078195444,0.00020754291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977756,0.00019423636,0.0005940939,0.00066346844,0.000280483,0.0004920772],"domain_scores_gemma":[0.99878794,0.000013699521,0.000355378,0.00037897375,0.00026691196,0.00019709488],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031870895,0.00035158737,0.00038298272,0.00013485082,0.000119358694,0.000027308035,0.00044612464,0.00034731024,0.0007818738],"category_scores_gemma":[0.00014817805,0.00037030678,0.0002330155,0.00021502105,0.00013198881,0.000012397903,0.00020266094,0.00021592423,0.000044850814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005287187,0.00019262976,0.000015020055,0.000048154572,0.00015796331,0.000027780588,0.0000610681,0.001097319,0.99580175,0.0009458545,0.0002913276,0.0008323891],"study_design_scores_gemma":[0.0024402374,0.00088634476,0.00000942197,0.000056626734,0.00006002386,0.0000124190265,0.00003684842,0.00015255297,0.9896927,0.00024537736,0.0060335696,0.0003739163],"about_ca_topic_score_codex":0.00015079656,"about_ca_topic_score_gemma":0.000009104022,"teacher_disagreement_score":0.0625325,"about_ca_system_score_codex":0.00008859502,"about_ca_system_score_gemma":0.0002674209,"threshold_uncertainty_score":0.9998749},"labels":[],"label_agreement":null},{"id":"W2182941348","doi":"10.1124/mol.104.004549","title":"Reciprocal Regulation of Agonist and Inverse Agonist Signaling Efficacy upon Short-Term Treatment of the Human δ-Opioid Receptor with an Inverse Agonist","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire en santé mentale de Montréal","funders":"","keywords":"Inverse agonist; Agonist; Chemistry; Partial agonist; Receptor; G protein; GTP'; Diprenorphine; μ-opioid receptor; Stereochemistry; Endocrinology; Pharmacology; Opioid receptor; Biochemistry; Biology","score_opus":0.015935248800061533,"score_gpt":0.2773263005057262,"score_spread":0.2613910517056647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2182941348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974119,0.00020685223,0.0013501941,0.00009828116,0.00020889867,0.0005984449,0.000024652078,0.000014697256,0.00008607739],"genre_scores_gemma":[0.9970319,0.00008786846,0.0022397167,0.00013885275,0.00014613241,0.000042128748,0.00020977415,0.000046182864,0.00005740756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998376,0.00020532706,0.00040312685,0.000517882,0.00019657238,0.00030107773],"domain_scores_gemma":[0.9991142,0.0000113678525,0.00023800418,0.00036710073,0.00012902769,0.00014027677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016672115,0.00029784045,0.0003452342,0.000067562476,0.00024168308,0.000023430905,0.0002247175,0.00021906555,0.000091000315],"category_scores_gemma":[0.000010338831,0.00023259927,0.00015342522,0.00014010484,0.0003594478,0.000011478182,0.0000871139,0.00011003723,0.0000012505017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042250266,0.00041425464,0.00054984435,0.00004098837,0.00018353715,0.000011555815,0.0003087406,0.0027585973,0.99406403,0.00022878726,0.00002773537,0.0009894517],"study_design_scores_gemma":[0.002790199,0.0024841884,0.00052384596,0.000034003126,0.00021056802,0.000023845387,0.00009723484,0.00011325275,0.9922238,0.000104356994,0.0011461091,0.0002486037],"about_ca_topic_score_codex":0.000097484415,"about_ca_topic_score_gemma":0.00008792999,"teacher_disagreement_score":0.0026453445,"about_ca_system_score_codex":0.00007907767,"about_ca_system_score_gemma":0.00017418955,"threshold_uncertainty_score":0.94851226},"labels":[],"label_agreement":null},{"id":"W2183331103","doi":"10.1124/mol.58.5.1137","title":"Sodium Dodecyl Sulfate-Stable Complexes of Echistatin and RGD-Dependent Integrins: A Novel Approach to Study Integrins","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"","keywords":"Integrin; Disintegrin; Gel electrophoresis; Chemistry; Alpha (finance); Polyacrylamide gel electrophoresis; Molecular biology; Biochemistry; Biology; Cell; Metalloproteinase; Enzyme; Medicine","score_opus":0.030986895407442365,"score_gpt":0.3381824492481747,"score_spread":0.3071955538407323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2183331103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98118585,0.0002854781,0.0054457677,0.0004958913,0.000071396535,0.0021631238,0.000031732663,0.00006035688,0.010260384],"genre_scores_gemma":[0.9905875,0.000060352308,0.0059545296,0.0011061041,0.00003982559,0.00020531563,0.000032421085,0.00006112985,0.001952841],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973159,0.00027582294,0.0005471642,0.00070841436,0.00057305954,0.0005796351],"domain_scores_gemma":[0.9987926,0.00008929296,0.00007791541,0.0004141757,0.00020278033,0.00042325672],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00051475567,0.0003117118,0.00066472864,0.0003705142,0.0000853878,0.000024118455,0.000282739,0.000115891315,0.0016976108],"category_scores_gemma":[0.00006759191,0.00027997614,0.00010261254,0.00046058034,0.0001899036,0.000041074094,0.00031403475,0.0006086372,0.000083167215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014220851,0.0045272806,0.00090428686,0.00013598928,0.00031316356,0.00041469818,0.0012013995,0.00022250554,0.9830777,0.00013950399,0.0008748266,0.0067665847],"study_design_scores_gemma":[0.0135787185,0.0031510426,0.009571922,0.000039571987,0.00043311066,0.00038965352,0.0017958346,0.0037698287,0.95687747,0.000058941834,0.009848918,0.00048501053],"about_ca_topic_score_codex":0.0004312958,"about_ca_topic_score_gemma":0.00002031468,"teacher_disagreement_score":0.026200227,"about_ca_system_score_codex":0.00012207375,"about_ca_system_score_gemma":0.00014681298,"threshold_uncertainty_score":0.99996525},"labels":[],"label_agreement":null},{"id":"W2186092389","doi":"10.1124/mol.105.015891","title":"Inactivation of the Pure Antiestrogen Fulvestrant and Other Synthetic Estrogen Molecules by UDP-Glucuronosyltransferase 1A Enzymes Expressed in Breast Tissue","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"","keywords":"Glucuronidation; Fulvestrant; Enzyme; Chemistry; Glucuronosyltransferase; Antiestrogen; Biochemistry; Estrogen; Estrogen receptor; Microsome; Biology; Cancer; Endocrinology; Breast cancer","score_opus":0.02167709174274309,"score_gpt":0.34478193430852655,"score_spread":0.3231048425657835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2186092389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98459345,0.008694531,0.00051516655,0.003688817,0.0004899163,0.00086939044,0.00055594306,0.000043459382,0.00054934487],"genre_scores_gemma":[0.99446297,0.0007021589,0.00018612771,0.0042298534,0.00014267603,0.0001296438,0.00001904926,0.000063611544,0.000063903426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968547,0.0010785199,0.00062132115,0.00055224856,0.0002411966,0.00065198017],"domain_scores_gemma":[0.9990243,0.00016491456,0.00021329531,0.00027643645,0.00007793545,0.00024312163],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004735205,0.00042215214,0.0004893417,0.00018169453,0.00014755293,0.000018914723,0.00053722673,0.00035511734,0.00063650584],"category_scores_gemma":[0.000019773954,0.00037221878,0.00013450767,0.00034072128,0.0005138551,0.00011071429,0.0001411743,0.0007323148,0.000015020236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043117563,0.0005884452,0.001815211,0.0000552731,0.00021407015,0.00003354729,0.00046376974,0.0015708315,0.9808921,0.0010756607,0.001066839,0.0117930705],"study_design_scores_gemma":[0.0029604605,0.000063204825,0.0005520721,0.000015156667,0.000307158,0.00007916358,0.000046641828,0.0021185619,0.8832696,0.00018381396,0.1100956,0.00030858186],"about_ca_topic_score_codex":0.000049339633,"about_ca_topic_score_gemma":0.000006978504,"teacher_disagreement_score":0.10902876,"about_ca_system_score_codex":0.000056891928,"about_ca_system_score_gemma":0.00012236243,"threshold_uncertainty_score":0.999873},"labels":[],"label_agreement":null},{"id":"W2188181971","doi":"10.1124/mol.58.1.37","title":"Functional Analysis of a Tryptophan-Less P-glycoprotein: A Tool for Tryptophan Insertion and Fluorescence Spectroscopy","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"Tryptophan; Mutant; Chinese hamster ovary cell; Biology; Biochemistry; P-glycoprotein; Wild type; Efflux; Molecular biology; Multiple drug resistance; Chemistry; Amino acid; Gene; Receptor","score_opus":0.01076471975415848,"score_gpt":0.27271043340882767,"score_spread":0.2619457136546692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2188181971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9727531,0.00042555496,0.025163142,0.0005400695,0.00012983594,0.000732981,0.000031278232,0.000035213274,0.00018883291],"genre_scores_gemma":[0.9930631,0.0001368269,0.005221093,0.0006660179,0.00008126343,0.00017312475,0.000117055904,0.000020685911,0.0005208589],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988503,0.000040250965,0.00030460677,0.00034682214,0.0001954088,0.0002626154],"domain_scores_gemma":[0.99957025,0.00002410948,0.00007264284,0.00014630758,0.00008860406,0.00009809323],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013328785,0.00016255003,0.00046634808,0.00024739304,0.00006387365,0.000006297219,0.00006398474,0.00011515124,0.0013792916],"category_scores_gemma":[0.0000060615926,0.00015011599,0.00023007946,0.0005000056,0.00010717633,0.000040904175,0.000007650859,0.000112929185,0.000004310887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002780424,0.00024935653,0.00052987406,0.0001224783,0.0009494186,0.00007096417,0.00006497746,0.000110176676,0.98821694,0.00040380046,0.00015634253,0.006345261],"study_design_scores_gemma":[0.0039263405,0.00043722472,0.021469906,0.000022524115,0.0027997103,0.000017338882,0.000022455632,0.0025276886,0.96727574,0.0002456691,0.0010984427,0.00015697652],"about_ca_topic_score_codex":0.000012737004,"about_ca_topic_score_gemma":0.00000606183,"teacher_disagreement_score":0.020941203,"about_ca_system_score_codex":0.000036203433,"about_ca_system_score_gemma":0.00007401408,"threshold_uncertainty_score":0.9995336},"labels":[],"label_agreement":null},{"id":"W2188792795","doi":"10.1124/mol.115.100529","title":"A Small Molecule Pyrazolo[3,4-d]Pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Myosin light-chain kinase; Phosphatase; Rho-associated protein kinase; Phosphorylation; Vascular smooth muscle; Myosin; Protein phosphatase 1; Protein kinase A; Myosin-light-chain phosphatase; Biology; Kinase; Muscle contraction; Dephosphorylation; Cell biology; Chemistry; Biochemistry; Endocrinology","score_opus":0.0275346134780252,"score_gpt":0.2797360000459211,"score_spread":0.25220138656789587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2188792795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.977567,0.0015048141,0.019354353,0.00023134523,0.00021653749,0.00070776854,0.000025892696,0.000023643717,0.00036865138],"genre_scores_gemma":[0.9971454,0.000017160248,0.0021045944,0.00021952674,0.0001691201,0.00007109202,0.00016663894,0.000054590273,0.00005186154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99801564,0.00035324908,0.00054204516,0.00047315075,0.00025890744,0.00035701154],"domain_scores_gemma":[0.9985366,0.000021258755,0.00036853636,0.00036387017,0.00051610527,0.0001936414],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041245954,0.00027210734,0.00037385887,0.00016087572,0.0000507393,0.00001265444,0.0002172761,0.00023976152,0.000055908913],"category_scores_gemma":[0.00026343297,0.0002915974,0.00020840528,0.00023667724,0.0001747938,0.000011413672,0.00022614015,0.0001515331,0.0000048876877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023814631,0.00023731518,0.0000622217,0.00013648003,0.00011836562,0.0000513041,0.00010768648,0.002881119,0.9951583,0.000109133405,0.00026664548,0.00063325925],"study_design_scores_gemma":[0.0019899209,0.00039458933,0.000082398394,0.00006175036,0.0001044468,0.000009831703,0.00007458343,0.0017885959,0.99251455,0.000063431195,0.0026433556,0.00027252606],"about_ca_topic_score_codex":0.00008664701,"about_ca_topic_score_gemma":0.000007837563,"teacher_disagreement_score":0.019578421,"about_ca_system_score_codex":0.000034283174,"about_ca_system_score_gemma":0.00022198992,"threshold_uncertainty_score":0.9999536},"labels":[],"label_agreement":null},{"id":"W2189532946","doi":"10.1124/mol.105.014514","title":"Opposite Effects of Histone Deacetylase Inhibitors on Glucocorticoid and Estrogen Signaling in Human Endometrial Ishikawa Cells","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Histone deacetylase; Promoter; Biology; Estrogen receptor; Histone acetyltransferase; Histone; Glucocorticoid receptor; Cancer research; PELP-1; HDAC11; Acetylation; Cell biology; Histone deacetylase inhibitor; Transcription factor; Molecular biology; Nuclear receptor; Glucocorticoid; Gene expression; Endocrinology; Biochemistry; Genetics; Gene; Cancer","score_opus":0.006656953966391741,"score_gpt":0.3204895098814146,"score_spread":0.31383255591502285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2189532946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960128,0.0022692084,0.00013120589,0.00012985588,0.0003310161,0.0008634182,0.000010768214,0.000014098712,0.00023762643],"genre_scores_gemma":[0.9984446,0.00008887363,0.00037523513,0.00041846355,0.00033490665,0.00008441628,0.000041089952,0.000056906458,0.00015549135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976487,0.0004184974,0.00050057913,0.0006211755,0.00029029258,0.00052071695],"domain_scores_gemma":[0.99916625,0.00010813198,0.00016226163,0.0002958465,0.000074966636,0.0001925383],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003696966,0.00028597028,0.00040327117,0.00042918755,0.000064687905,0.000013670067,0.00023679757,0.00026917094,0.000037204372],"category_scores_gemma":[0.000111958245,0.00032373372,0.00014904706,0.00029424593,0.00022391004,0.000008096599,0.00020082049,0.00033530488,0.000021205246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040271188,0.00039154425,0.000119497905,0.00010272771,0.00009143886,0.00017193086,0.00007053452,0.0015255051,0.9946369,0.00003625398,0.0008712209,0.0015797227],"study_design_scores_gemma":[0.0051699537,0.0011791807,0.00003643361,0.000033008524,0.000051776704,0.000017784201,0.000008907334,0.00011184446,0.9892207,0.000004414154,0.0038997803,0.00026625334],"about_ca_topic_score_codex":0.00004547634,"about_ca_topic_score_gemma":0.000010425623,"teacher_disagreement_score":0.0054162485,"about_ca_system_score_codex":0.00013031729,"about_ca_system_score_gemma":0.000111456175,"threshold_uncertainty_score":0.9999215},"labels":[],"label_agreement":null},{"id":"W2197820014","doi":"10.1124/mol.58.1.207","title":"Induction of Metabolism-Dependent and -Independent Neutrophil Apoptosis by Clozapine","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":135,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Clozapine; Apoptosis; Pharmacology; Chemistry; Immunology; Biochemistry; Biology; Medicine; Schizophrenia (object-oriented programming); Psychiatry","score_opus":0.021198998078426345,"score_gpt":0.31372341084199223,"score_spread":0.2925244127635659,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2197820014","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99604917,0.0003942393,0.000039173086,0.001615532,0.0006294585,0.00045026606,0.000031640157,0.00006196318,0.0007285585],"genre_scores_gemma":[0.99071324,0.0033892668,0.000012476591,0.0046486445,0.000070927155,0.00006997485,0.0000011916767,0.000031958516,0.0010623379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99706566,0.00070554006,0.00035246235,0.0008131128,0.000492773,0.0005704516],"domain_scores_gemma":[0.9992845,0.000113212605,0.00010759598,0.00021617317,0.000045227363,0.00023328839],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024828766,0.00023567305,0.00032970824,0.00021619223,0.00018542957,0.000027508535,0.00047050856,0.000116655785,0.001707118],"category_scores_gemma":[0.00004992012,0.00022912916,0.00007929711,0.00054058013,0.0005711713,0.00020842269,0.00017144073,0.0004835706,0.000084690415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002339422,0.00028807772,0.000020627524,0.000011844046,0.000013069664,0.00011540389,0.00003937267,0.00006786059,0.98987323,0.00013684123,0.0021868746,0.0070128655],"study_design_scores_gemma":[0.0016896602,0.00025054842,0.00011884203,0.0000017562544,0.00006425576,0.00014176752,0.0000055249034,0.00022687174,0.9825985,0.000082368795,0.014644802,0.00017513355],"about_ca_topic_score_codex":0.000018569077,"about_ca_topic_score_gemma":2.0571177e-7,"teacher_disagreement_score":0.012457927,"about_ca_system_score_codex":0.000024421997,"about_ca_system_score_gemma":0.00005677149,"threshold_uncertainty_score":0.99920547},"labels":[],"label_agreement":null},{"id":"W2212055661","doi":"10.1124/mol.115.100792","title":"Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":88,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"Deutsche Forschungsgemeinschaft","keywords":"TRPC6; TRPC; TRPC3; Transient receptor potential channel; Chemistry; Diacylglycerol kinase; Pharmacology; Biochemistry; Receptor; Biology; Protein kinase C; Signal transduction","score_opus":0.033214592137033344,"score_gpt":0.31954211624935064,"score_spread":0.2863275241123173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2212055661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99574953,0.00008903215,0.0009862955,0.001271587,0.0012069783,0.00022610232,0.000004552385,0.000027017042,0.00043888867],"genre_scores_gemma":[0.99880517,0.00004288797,0.0000364643,0.0005422052,0.00006295681,0.00001972602,0.0000036311947,0.000011004959,0.00047593645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905854,0.00021054827,0.00018859166,0.00023547253,0.00017010377,0.00013671491],"domain_scores_gemma":[0.999634,0.000025652149,0.00011620497,0.000058603357,0.000069939066,0.00009560219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021198728,0.00008037692,0.00011023762,0.00008893417,0.000041167474,0.000015173527,0.00009461655,0.000059190425,0.000038156406],"category_scores_gemma":[0.00010719285,0.00007424761,0.000031801384,0.00014800912,0.00010272147,0.00008328751,0.00006334498,0.00007950898,0.000053035834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039106453,0.000061022314,0.0000067489873,0.000010372733,0.00000558024,0.000018490133,0.00032711658,0.0002693106,0.99691224,0.00030904802,0.0009433674,0.0010976053],"study_design_scores_gemma":[0.00075666304,0.00009935381,0.000009791462,0.0000027338406,0.000025920073,0.000029131474,0.0000444109,0.0009002362,0.9950072,0.00062136166,0.002429262,0.00007392373],"about_ca_topic_score_codex":0.000011395236,"about_ca_topic_score_gemma":1.7744293e-7,"teacher_disagreement_score":0.0030556405,"about_ca_system_score_codex":0.000020977981,"about_ca_system_score_gemma":0.000040248673,"threshold_uncertainty_score":0.30277297},"labels":[],"label_agreement":null},{"id":"W2212855644","doi":"10.1124/mol.115.101980","title":"Biased Type 1 Cannabinoid Receptor Signaling Influences Neuronal Viability in a Cell Culture Model of Huntington Disease","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Cannabinoid receptor; Cannabinoid; Endocannabinoid system; Cannabidiol; Biology; Agonist; Signal transduction; Viability assay; Medium spiny neuron; Receptor; Pharmacology; Cannabinoid receptor type 2; Cell biology; Neuroscience; Biochemistry; Cell; Basal ganglia; Psychology; Cannabis; Central nervous system; Psychiatry","score_opus":0.03032617256808773,"score_gpt":0.3296348039892438,"score_spread":0.29930863142115605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2212855644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946696,0.00045955062,0.00007402684,0.0034655984,0.00019550559,0.00061814167,0.000027137832,0.000028588525,0.00046183928],"genre_scores_gemma":[0.996823,0.000018917839,0.00031111247,0.0015479554,0.000074007025,0.00006983385,0.000038241276,0.000026697584,0.001090194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808514,0.00024483816,0.00037403213,0.00040748258,0.00046348295,0.0004250427],"domain_scores_gemma":[0.9986323,0.000009857752,0.00010089026,0.00022270587,0.0005174359,0.0005167855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049040205,0.00018599181,0.00035590434,0.00019293623,0.00003065366,0.0000102357435,0.00018666423,0.00011714863,0.00019566814],"category_scores_gemma":[0.00026307037,0.00016783315,0.0001168877,0.000492875,0.00020653835,0.000059471386,0.00010859546,0.0004202981,0.0000134622005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013836009,0.0005143554,0.009080592,0.00023376156,0.000021402175,0.000044418328,0.00037308375,0.015293152,0.9546735,0.000016995073,0.018229932,0.00013515388],"study_design_scores_gemma":[0.0042867996,0.00073532364,0.002734918,0.000033791064,0.00014111857,0.000002311381,0.00013787669,0.021364525,0.96139365,0.00018597467,0.008727622,0.00025610736],"about_ca_topic_score_codex":0.00014645846,"about_ca_topic_score_gemma":0.000006073865,"teacher_disagreement_score":0.009502309,"about_ca_system_score_codex":0.00015129962,"about_ca_system_score_gemma":0.0013271368,"threshold_uncertainty_score":0.6844037},"labels":[],"label_agreement":null},{"id":"W2253408620","doi":"10.1124/mol.115.099689","title":"Potentiators of Defective ΔF508–CFTR Gating that Do Not Interfere with Corrector Action","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Biomedical Imaging and Bioengineering; National Eye Institute; Vertex Pharmaceuticals","keywords":"Potentiator; ΔF508; Action (physics); Gating; Chemistry; Cystic fibrosis transmembrane conductance regulator; Genetics; Biochemistry; Biology; Physics; Biophysics; Gene","score_opus":0.04684233548738552,"score_gpt":0.3716873059614866,"score_spread":0.32484497047410105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2253408620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987479,0.0003504175,0.009754557,0.00028485784,0.00042892512,0.00051847624,0.000006649293,0.000047778754,0.0011293535],"genre_scores_gemma":[0.99701715,0.000012453711,0.0024024046,0.00028894944,0.00007093979,0.00005311904,0.000013183979,0.00003115323,0.000110658475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986531,0.0001867501,0.00017678067,0.00028380528,0.0003941798,0.00030535777],"domain_scores_gemma":[0.9990596,0.000107352396,0.00013349428,0.00015732735,0.00030665702,0.00023552902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021619802,0.0001521227,0.00031418377,0.00016400841,0.000031808504,0.000009563267,0.000102820326,0.00006883078,0.00019636708],"category_scores_gemma":[0.00018991326,0.00012341273,0.00007215156,0.0002225663,0.0001760699,0.00008710743,0.00008342889,0.0002969909,0.000026313568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026728122,0.00016284184,0.0107796285,0.00011592954,0.00028211146,0.000259231,0.00030243932,0.00021972934,0.97922385,0.00002634684,0.0011234453,0.0048316424],"study_design_scores_gemma":[0.0035283112,0.0016448579,0.0048349984,0.00008265015,0.00021208519,0.00021121245,0.0006886649,0.0007098676,0.9864583,0.00003727367,0.0014676809,0.00012407075],"about_ca_topic_score_codex":0.00006266007,"about_ca_topic_score_gemma":0.000011333417,"teacher_disagreement_score":0.009538153,"about_ca_system_score_codex":0.00018977866,"about_ca_system_score_gemma":0.0001951684,"threshold_uncertainty_score":0.5032625},"labels":[],"label_agreement":null},{"id":"W2264960028","doi":"10.1124/mol.59.3.453","title":"The Catalytic DNA Topoisomerase II Inhibitor Dexrazoxane (ICRF-187) Induces Differentiation and Apoptosis in Human Leukemia K562 Cells","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute","keywords":"Dexrazoxane; K562 cells; Apoptosis; Topoisomerase; Biology; Leukemia; Cell biology; Cell cycle; Cancer research; Molecular biology; Chemistry; Biochemistry; DNA; Immunology; Genetics; Anthracycline","score_opus":0.009705788547481262,"score_gpt":0.26551584018716295,"score_spread":0.2558100516396817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2264960028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969365,0.0012940145,0.00025565323,0.00048792106,0.00051874423,0.00033221723,0.000007963059,0.000012453836,0.00015452792],"genre_scores_gemma":[0.9969819,0.001137137,0.000024804362,0.0010900004,0.0002064921,0.00009312729,0.000069740156,0.00003081189,0.00036595372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987189,0.0001090322,0.00026150103,0.00040909255,0.00011678877,0.00038465066],"domain_scores_gemma":[0.9995127,0.000015062462,0.00009820764,0.00023111164,0.000043933338,0.000098984245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017550154,0.00021193104,0.00017606755,0.00007618379,0.00027924913,0.00003762646,0.00020913585,0.00017984126,0.00002556115],"category_scores_gemma":[0.000006784012,0.00018694712,0.00007028142,0.00013249609,0.00010777866,0.00000598407,0.00021193213,0.00017198143,0.0000031580307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009348189,0.000073255156,0.00008725005,0.000008970215,0.0000773145,0.000013849008,0.0000808943,0.000038541984,0.9954003,0.00014820797,0.00034201104,0.003635915],"study_design_scores_gemma":[0.0014517936,0.00030032638,0.0002735436,0.0000058010955,0.0000656137,0.000015062166,0.000050225746,0.00010917551,0.98136437,0.000230337,0.015917405,0.00021633191],"about_ca_topic_score_codex":0.000077510675,"about_ca_topic_score_gemma":0.00011709289,"teacher_disagreement_score":0.015575395,"about_ca_system_score_codex":0.00008061344,"about_ca_system_score_gemma":0.00007133938,"threshold_uncertainty_score":0.7623482},"labels":[],"label_agreement":null},{"id":"W2309225086","doi":"10.1124/mol.115.102723","title":"Thrombin-Mediated Direct Activation of Proteinase-Activated Receptor-2: Another Target for Thrombin Signaling","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Western University","funders":"Canadian Institutes of Health Research","keywords":"Thrombin; Thrombin receptor; Cell biology; Protease-activated receptor; Receptor; Signal transduction; Biochemistry; Trypsin; Chemistry; Ligand (biochemistry); G protein-coupled receptor; Thrombomodulin; Biology; Enzyme; Immunology; Platelet","score_opus":0.024065997714301925,"score_gpt":0.2981026501286196,"score_spread":0.2740366524143177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2309225086","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9562151,0.00006472159,0.03732207,0.0030397992,0.00036852036,0.002062416,0.000037738344,0.00015780574,0.00073182955],"genre_scores_gemma":[0.9940433,0.0000133044905,0.003911334,0.001268704,0.000082734136,0.0002774109,0.00007607997,0.00006805689,0.00025911312],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985389,0.00017952498,0.00036802673,0.00036642005,0.00022319904,0.00032390136],"domain_scores_gemma":[0.9990126,0.00017830657,0.00024812232,0.00019595913,0.0002672567,0.000097758544],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002857336,0.00021009363,0.00048071094,0.0001718521,0.000058567675,0.0000050811036,0.00009958903,0.00019667788,0.0021932253],"category_scores_gemma":[0.00015571252,0.00016040249,0.00015074834,0.0002772324,0.00009229354,0.000091474205,0.00003084792,0.00009973083,0.000032452997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005395768,0.0004274524,0.00007994702,0.00007592933,0.00039286588,0.0000042817064,0.00006422244,0.000011248932,0.99503154,0.00050853763,0.0019362291,0.0009281603],"study_design_scores_gemma":[0.0062351115,0.0009371482,0.0001586385,0.000106651,0.00015100767,0.0000049397054,0.000014957848,0.00012506475,0.98730505,0.0006121421,0.0041656257,0.00018366353],"about_ca_topic_score_codex":0.000008964558,"about_ca_topic_score_gemma":2.0916926e-7,"teacher_disagreement_score":0.037828162,"about_ca_system_score_codex":0.00008566891,"about_ca_system_score_gemma":0.00012285727,"threshold_uncertainty_score":0.9987189},"labels":[],"label_agreement":null},{"id":"W2314791461","doi":"10.1124/mol.59.5.1196","title":"<i>Tripterygium wilfordii</i>Hook F Extract Suppresses Proinflammatory Cytokine-Induced Expression of Matrix Metalloproteinase Genes in Articular Chondrocytes by Inhibiting Activating Protein-1 and Nuclear Factor-κB Activities","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Natural Compounds in Disease Treatment","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Tripterygium wilfordii; Proinflammatory cytokine; p38 mitogen-activated protein kinases; Matrix metalloproteinase; Arthritis; Cytokine; Tumor necrosis factor alpha; Pharmacology; Chondrocyte; Tripterygium; Chemistry; Protein kinase A; Inflammation; Kinase; Medicine; Cancer research; Cartilage; Immunology; Biochemistry; Pathology","score_opus":0.011555372968675781,"score_gpt":0.2890578151118919,"score_spread":0.2775024421432161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2314791461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941203,0.0035083448,0.0000670916,0.00029031892,0.000082147046,0.0016415071,0.000019157893,0.00011002891,0.00016108947],"genre_scores_gemma":[0.99749815,0.00008978416,0.0017335508,0.00013823734,0.00007465524,0.00026393236,0.000025807649,0.0000792488,0.00009664089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767065,0.0002752467,0.00056150864,0.0005639419,0.00039686225,0.00053178275],"domain_scores_gemma":[0.99902195,0.00009628452,0.0003293354,0.00024992568,0.00008777114,0.00021471865],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016026622,0.00041876142,0.000676776,0.00033998242,0.00010947124,0.000030605966,0.00014181505,0.0001944564,0.00019832133],"category_scores_gemma":[0.00008634337,0.00037721667,0.00015139402,0.00028155377,0.00013362113,0.00034225645,0.00019867507,0.00044722954,0.0000028819272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010278958,0.00048079976,0.0009324269,0.00033792615,0.0001623813,0.0017815224,0.00023692295,0.000010094209,0.9917883,0.000009793085,0.0000745718,0.0031573342],"study_design_scores_gemma":[0.003919286,0.00039716816,0.00044181666,0.00028027178,0.00015541058,0.00022882032,0.0002303644,0.0001461185,0.9927894,0.000029489423,0.0010685833,0.00031325774],"about_ca_topic_score_codex":0.00004120127,"about_ca_topic_score_gemma":0.0000016758148,"teacher_disagreement_score":0.0034185606,"about_ca_system_score_codex":0.00018251344,"about_ca_system_score_gemma":0.00010016385,"threshold_uncertainty_score":0.999868},"labels":[],"label_agreement":null},{"id":"W2321503397","doi":"10.1124/mol.60.5.999","title":"Allosteric Effects of G Protein Overexpression on the Binding of β-Adrenergic Ligands with Distinct Inverse Efficacies","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Allosteric regulation; Adenylyl cyclase; G protein; Inverse agonist; Receptor; Intrinsic activity; BETA (programming language); Chemistry; Biochemistry; Sf9; Allosteric modulator; Recombinant DNA; Biology; Antagonist; Agonist; Gene; Spodoptera","score_opus":0.006966070283914955,"score_gpt":0.2332503037194656,"score_spread":0.22628423343555062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2321503397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997934,0.00015037999,0.0010673505,0.00006518641,0.00006942346,0.00040314737,0.000010964761,0.0000073527012,0.00029218587],"genre_scores_gemma":[0.99920577,0.000034324217,0.0002045186,0.00018443176,0.000050781768,0.000078527366,0.000040156236,0.000023738154,0.0001777292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907696,0.00013041604,0.00018525256,0.00024670383,0.0001542634,0.00020641851],"domain_scores_gemma":[0.99946034,0.000047223846,0.00017673308,0.00020774886,0.000056821413,0.000051151972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117922085,0.00016685862,0.00019459552,0.000053920725,0.000057015364,0.0000055083706,0.00020477083,0.0001049532,0.00032635583],"category_scores_gemma":[0.000044078603,0.000108219436,0.00008902621,0.00014031076,0.00011394801,0.0000024595265,0.000098262986,0.00009767006,0.0000028228358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040844316,0.00011274183,0.000062622436,0.000059613827,0.00009870149,0.000032947246,0.000035339446,0.00029995712,0.9981347,0.00010372474,0.00036492574,0.0002862927],"study_design_scores_gemma":[0.00089851086,0.0012128877,0.00005968965,0.00013741806,0.000039620438,0.000011809035,0.000022160822,0.00010999246,0.9958904,0.000019731175,0.0014720283,0.00012576696],"about_ca_topic_score_codex":0.0000062585905,"about_ca_topic_score_gemma":0.0000010859504,"teacher_disagreement_score":0.0022443058,"about_ca_system_score_codex":0.000008372244,"about_ca_system_score_gemma":0.000036062473,"threshold_uncertainty_score":0.44130605},"labels":[],"label_agreement":null},{"id":"W2325909692","doi":"10.1124/mol.114.096578","title":"A Renal-Like Organic Anion Transport System in the Ciliary Epithelium of the Bovine and Human Eye","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Eye Institute; Canadian Institutes of Health Research; Radboud Universiteit","keywords":"Ciliary body; Organic anion transporter 1; Ussing chamber; Epithelial polarity; Chemistry; Probenecid; Molecular biology; Apical membrane; Epithelium; Biochemistry; Biology; Transporter; Pharmacology; Membrane; In vitro; Gene","score_opus":0.011563980180690913,"score_gpt":0.2681192561950531,"score_spread":0.2565552760143622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2325909692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947531,0.000915816,0.00050599064,0.0016229264,0.00031217953,0.00063182914,0.0000070189017,0.000025263473,0.0012258278],"genre_scores_gemma":[0.9983257,0.000019922429,0.00005307508,0.0012716879,0.00005043852,0.000029041736,0.00001320288,0.000020210697,0.00021673861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988666,0.00017359886,0.00028883226,0.00020572418,0.0002571011,0.00020811107],"domain_scores_gemma":[0.9995248,0.000012336947,0.000080241625,0.00023965501,0.00006388978,0.000079094425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005870692,0.00013640005,0.00027969008,0.00006882112,0.00004733779,0.0000023673308,0.00018748459,0.00009455313,0.000028215847],"category_scores_gemma":[0.000003796435,0.00007790204,0.00007964224,0.0002518977,0.00012538502,0.000020492234,0.000018214581,0.00023870775,0.00000271476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002496114,0.00016504672,0.007261544,0.00022287258,0.00006625019,0.0006287441,0.0009625918,0.000008267515,0.9892534,0.0008032387,0.0003103463,0.000068068424],"study_design_scores_gemma":[0.0147877885,0.0012365248,0.14393213,0.0004411366,0.0015666673,0.000496403,0.0025532348,0.000210834,0.8118516,0.00038708508,0.022099352,0.00043721055],"about_ca_topic_score_codex":0.000052063126,"about_ca_topic_score_gemma":0.00007411264,"teacher_disagreement_score":0.1774018,"about_ca_system_score_codex":0.000044573302,"about_ca_system_score_gemma":0.000104903964,"threshold_uncertainty_score":0.3176753},"labels":[],"label_agreement":null},{"id":"W2327043100","doi":"10.1124/mol.115.102434","title":"Inhibition of GLI1 Expression by Targeting the CRD-BP–GLI1 mRNA Interaction Using a Specific Oligonucleotide","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Northern British Columbia","funders":"","keywords":"GLI1; RNA; Biology; Molecular biology; Messenger RNA; Oligonucleotide; Circular RNA; RNA-binding protein; Hedgehog signaling pathway; Cell biology; Genetics; Gene; Signal transduction","score_opus":0.017588561707969314,"score_gpt":0.2887972877912122,"score_spread":0.2712087260832429,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2327043100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800259,0.0018584838,0.016607514,0.00041876463,0.0005550977,0.00025806052,0.00002816527,0.000020953823,0.0002270605],"genre_scores_gemma":[0.99815065,0.0002823008,0.0005929605,0.00052812824,0.0002909672,0.00002998112,0.000029645042,0.000039968632,0.00005537851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842423,0.0003234927,0.00036514617,0.00040664003,0.00015496997,0.00032552733],"domain_scores_gemma":[0.99926865,0.000050647148,0.00024538906,0.00022865437,0.00014477328,0.000061911545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003109699,0.00020976343,0.00020313528,0.000060755894,0.0001462642,0.000011444225,0.00018155562,0.00013755941,0.00007959055],"category_scores_gemma":[0.00007613044,0.00014259425,0.00013099865,0.000106035215,0.00020646081,0.000010120572,0.00022516161,0.00012465031,0.000013502383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014113523,0.00007010943,0.00013587765,0.000015059823,0.000079006575,0.000015796733,0.0000920638,0.00013790953,0.9871168,0.000011481007,0.011267419,0.0009173351],"study_design_scores_gemma":[0.0008014448,0.00012945716,0.000023601391,0.000046057095,0.00003965692,0.00001557542,0.00010504508,0.0000751285,0.96490103,0.000033556156,0.03365806,0.0001713823],"about_ca_topic_score_codex":0.000010909872,"about_ca_topic_score_gemma":9.873138e-7,"teacher_disagreement_score":0.022390643,"about_ca_system_score_codex":0.000045955843,"about_ca_system_score_gemma":0.00003704096,"threshold_uncertainty_score":0.58148247},"labels":[],"label_agreement":null},{"id":"W2329467994","doi":"10.1124/mol.112.083618","title":"Transport Function and Transcriptional Regulation of a Liver-Enriched Human Organic Anion Transporting Polypeptide 2B1 Transcriptional Start Site Variant","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Organic anion-transporting polypeptide; Function (biology); Transcriptional regulation; Chemistry; Biology; Biochemistry; Cell biology; Computational biology; Gene; Gene expression; Transporter","score_opus":0.010272487948568441,"score_gpt":0.2338629767093959,"score_spread":0.22359048876082746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2329467994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92930114,0.00083136995,0.06757936,0.0007337096,0.00024272726,0.00091917237,0.000035255012,0.000085891676,0.00027135527],"genre_scores_gemma":[0.99665415,0.000082386185,0.0013631035,0.0006414341,0.00012392824,0.000068470516,0.00064146577,0.000053377167,0.00037169355],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99791664,0.00008833387,0.0007084906,0.00048102695,0.00042365468,0.0003818458],"domain_scores_gemma":[0.9992226,0.00001577611,0.00017341063,0.00015566954,0.00021391056,0.00021865888],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002843499,0.00029406778,0.0004944934,0.00023950594,0.00014350085,0.000008678198,0.00007897833,0.00022924079,0.0043892283],"category_scores_gemma":[0.0000024212495,0.00028912124,0.00022952324,0.00028235078,0.00016082407,0.00021307153,0.0000038484914,0.0003008316,0.00001766839],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056909083,0.00039052614,0.0029929057,0.00028722527,0.00024721862,0.00009367985,0.0006823097,0.00004140046,0.98869175,0.0055155084,0.000046965524,0.00044140915],"study_design_scores_gemma":[0.0058425716,0.0007002016,0.80378115,0.000075367294,0.0013475886,0.00013029789,0.00010958092,0.0005624583,0.18492235,0.0015941326,0.00059184554,0.00034248448],"about_ca_topic_score_codex":0.0001507789,"about_ca_topic_score_gemma":0.00008143238,"teacher_disagreement_score":0.8037694,"about_ca_system_score_codex":0.00005860064,"about_ca_system_score_gemma":0.00010213405,"threshold_uncertainty_score":0.9999561},"labels":[],"label_agreement":null},{"id":"W2332807180","doi":"10.1124/mol.110.068379","title":"Rab GTPases Bind at a Common Site within the Angiotensin II Type I Receptor Carboxyl-Terminal Tail: Evidence that Rab4 Regulates Receptor Phosphorylation, Desensitization, and Resensitization","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Rab; GTPase; Endosome; Biology; Cell biology; Dephosphorylation; Receptor; Biochemistry; Phosphorylation","score_opus":0.011905630675638866,"score_gpt":0.2535041133401588,"score_spread":0.24159848266451994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2332807180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935909,0.0017269136,0.0013534479,0.0018350824,0.00088291825,0.000521145,0.000019604964,0.000037423437,0.000032577955],"genre_scores_gemma":[0.9942413,0.00043723852,0.0006112258,0.0010639996,0.0002776013,0.000019076148,0.0026155447,0.00005134358,0.0006826926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983011,0.00029392345,0.00031836343,0.0005582471,0.0002244728,0.00030387598],"domain_scores_gemma":[0.99882114,0.00005249348,0.00025508789,0.00037750063,0.0003612862,0.00013249216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000484257,0.0002752409,0.0002304105,0.000079716614,0.00047539367,0.000041876196,0.00016154378,0.00033394012,0.00015064527],"category_scores_gemma":[0.00011964696,0.00024226215,0.000087326545,0.00024970266,0.00037458175,0.000019809466,0.00015758639,0.00026475446,0.000018897774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005727076,0.000037521426,0.0078078806,0.000016031017,0.00007071451,0.000031479907,0.00032436015,0.00022485903,0.98804164,0.000051502015,0.0025839733,0.00023733656],"study_design_scores_gemma":[0.00063004694,0.00024382136,0.003011998,0.000023644388,0.00013964939,0.00012534452,0.000036405017,0.0013443821,0.9689681,0.000032107844,0.025147717,0.00029679877],"about_ca_topic_score_codex":0.00007982371,"about_ca_topic_score_gemma":0.00031912554,"teacher_disagreement_score":0.022563744,"about_ca_system_score_codex":0.000028595523,"about_ca_system_score_gemma":0.00009280899,"threshold_uncertainty_score":0.9879164},"labels":[],"label_agreement":null},{"id":"W2333253878","doi":"10.1124/mol.114.094730","title":"A Mutation in the Intracellular Loop III/IV of Mosquito Sodium Channel Synergizes the Effect of Mutations in Helix IIS6 on Pyrethroid Resistance","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Mutation; Pyrethroid; Sodium channel; Intracellular; Genetics; Biology; Helix (gastropod); Molecular biology; Chemistry; Sodium; Gene; Pesticide; Zoology","score_opus":0.00592420257721213,"score_gpt":0.2592096811764011,"score_spread":0.25328547859918893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333253878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99242586,0.00041523075,0.0044483426,0.0012848964,0.00042359906,0.000553213,0.0000058310648,0.00000567458,0.000437355],"genre_scores_gemma":[0.9989454,0.00003455436,0.00001945436,0.0004949696,0.00013888722,0.00014600257,0.00009101834,0.000015866404,0.000113807044],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998135,0.00087198813,0.00035006512,0.00026462297,0.00018002697,0.0001983153],"domain_scores_gemma":[0.99928695,0.00018521259,0.0001825882,0.0002452015,0.00007611378,0.000023929013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094220944,0.00015215122,0.00020514888,0.000128028,0.00005448468,0.000006602029,0.00023101535,0.0001449842,0.000014831022],"category_scores_gemma":[0.0001829524,0.00010712842,0.00009053852,0.00030165812,0.00018213862,0.0000050468007,0.000037847443,0.00016089449,0.0000028168165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007542468,0.00009768792,0.000087245826,0.000055555098,0.00003642212,0.000009847789,0.00037985173,0.023861226,0.97323155,0.00044797617,0.0005253896,0.000513005],"study_design_scores_gemma":[0.0022898435,0.00073297706,0.00062733144,0.00001871367,0.00004000424,0.0000061962937,0.00015321172,0.007484973,0.9868962,0.0002119174,0.0014309385,0.00010766937],"about_ca_topic_score_codex":0.00002615522,"about_ca_topic_score_gemma":0.000046436904,"teacher_disagreement_score":0.016376253,"about_ca_system_score_codex":0.000019628375,"about_ca_system_score_gemma":0.000030399633,"threshold_uncertainty_score":0.436857},"labels":[],"label_agreement":null},{"id":"W2333488286","doi":"10.1124/mol.114.093476","title":"Role of SAP97 in the Regulation of 5-HT2AR Endocytosis and Signaling","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; HEK 293 cells; Gene knockdown; Cell biology; Internalization; Biology; Ankyrin repeat; Receptor; Biochemistry; Gene","score_opus":0.005161136667635055,"score_gpt":0.2408256091475777,"score_spread":0.23566447247994265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333488286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99499434,0.0007497527,0.0036180064,0.00006651535,0.00004404458,0.00013988669,0.0000022180905,0.0000020930793,0.0003831282],"genre_scores_gemma":[0.9988731,0.00004911763,0.00074216374,0.00024225716,0.000049497212,0.000014111586,0.000013430415,0.00000957283,0.0000067350875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991723,0.00023792872,0.00020805272,0.00016744786,0.00008817424,0.00012615218],"domain_scores_gemma":[0.99968433,0.000029979961,0.00010359668,0.0001203654,0.00004007406,0.000021679605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040198088,0.0000831291,0.00014238982,0.00005082126,0.00002151659,0.0000034747197,0.00013022199,0.00008286663,0.000056124078],"category_scores_gemma":[0.000026905624,0.00006958354,0.000050596485,0.00007488651,0.000059850743,0.000002125532,0.000047960497,0.00005913646,4.3294156e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004227035,0.000032785745,0.0003304705,0.000015964026,0.000024009263,4.949804e-7,0.00011693459,0.00063616893,0.9957641,0.00086343253,0.000028356071,0.0021450354],"study_design_scores_gemma":[0.0005066028,0.00020500374,0.0005681338,0.0000060890006,0.000028442513,0.0000061733153,0.00008666067,0.00089895795,0.9951268,0.0008360824,0.0016646588,0.000066411885],"about_ca_topic_score_codex":0.000017276256,"about_ca_topic_score_gemma":0.0000024480098,"teacher_disagreement_score":0.0038787595,"about_ca_system_score_codex":0.0000032700623,"about_ca_system_score_gemma":0.000014319183,"threshold_uncertainty_score":0.28375345},"labels":[],"label_agreement":null},{"id":"W2333621268","doi":"10.1124/mol.116.103465","title":"Antagonism of Dopamine Receptor 2 Long Affects Cannabinoid Receptor 1 Signaling in a Cell Culture Model of Striatal Medium Spiny Projection Neurons","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Agonist; Chemistry; Stereochemistry; Receptor; Biochemistry","score_opus":0.014302822586780785,"score_gpt":0.29978733436268273,"score_spread":0.28548451177590195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333621268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908524,0.0004513195,0.0019465251,0.0047282465,0.00047085364,0.0012275424,0.00009692708,0.000033153134,0.00019303031],"genre_scores_gemma":[0.99492884,0.0002494512,0.0002959687,0.00022398485,0.0001800215,0.00015347566,0.00004709344,0.000053320935,0.0038678763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977866,0.0002588263,0.0004841985,0.0004739942,0.0004636843,0.00053272815],"domain_scores_gemma":[0.9989966,0.000018735795,0.00023066056,0.00024756667,0.0002889167,0.00021752086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041512592,0.00025119432,0.0005619983,0.00040703357,0.000036616148,0.000005385755,0.00019539689,0.00023107439,0.0002989902],"category_scores_gemma":[0.00010637291,0.00018850753,0.00018719299,0.0004709044,0.00023542186,0.00008292191,0.00012422935,0.0003870691,0.000007791944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095446466,0.0005259526,0.0005505482,0.0004183808,0.000060077113,0.000055131706,0.0002396037,0.00031902562,0.9758003,0.000012462825,0.019112911,0.0019511778],"study_design_scores_gemma":[0.0055767545,0.0012701731,0.00023214283,0.00009465182,0.00010345562,0.000019254607,0.000066561595,0.00097364554,0.9882139,0.000007076183,0.0032633003,0.00017911494],"about_ca_topic_score_codex":0.00012950104,"about_ca_topic_score_gemma":0.000014338221,"teacher_disagreement_score":0.01584961,"about_ca_system_score_codex":0.00020628778,"about_ca_system_score_gemma":0.0006841294,"threshold_uncertainty_score":0.7687114},"labels":[],"label_agreement":null},{"id":"W2338301901","doi":"10.1016/s0026-895x(24)26455-5","title":"High-Affinity Binding of Peptide Agonists to the Human B1 Bradykinin Receptor Depends on Interaction between the Peptide N-Terminal l-Lysine and the Fourth Extracellular Domain of the Receptor","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Purdue Pharma (Canada)","funders":"National Institute of General Medical Sciences","keywords":"Peptide; Receptor; Chemistry; Kallidin; Bradykinin receptor; Agonist; Bradykinin; Enzyme-linked receptor; Protease-activated receptor 2; Transmembrane domain; C-terminus; Biochemistry; Stereochemistry; Kinin; Amino acid","score_opus":0.01541448645209999,"score_gpt":0.2912403522401479,"score_spread":0.2758258657880479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2338301901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832956,0.00036658335,0.00012019078,0.0142027885,0.0004340067,0.0010602587,0.000037509908,0.000026496215,0.00045652772],"genre_scores_gemma":[0.9962489,0.000063883526,0.0002313135,0.0012982312,0.000495785,0.000066128436,0.000049355695,0.000042082596,0.0015043105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972878,0.000878276,0.00066398404,0.00037838373,0.00042941517,0.00036213917],"domain_scores_gemma":[0.9982797,0.0005795712,0.00039326458,0.0005354127,0.000099815086,0.000112265494],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001137769,0.0002930067,0.00054231007,0.000110719535,0.00047469366,0.000029122495,0.00046578457,0.000120448734,0.0011110145],"category_scores_gemma":[0.00009415671,0.00015076097,0.00028721016,0.00039844998,0.00057648,0.000060510985,0.00013743088,0.00050638587,0.00003854721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002564407,0.00041616458,0.011249468,0.00010432732,0.00096567837,0.00004556584,0.004312829,0.0006467706,0.9392206,0.002432514,0.010262498,0.027779162],"study_design_scores_gemma":[0.008307818,0.0010023694,0.05267085,0.00026759232,0.0013329479,0.00014701259,0.0004952532,0.00024607783,0.8528747,0.00042581974,0.0818305,0.00039905572],"about_ca_topic_score_codex":0.0002550578,"about_ca_topic_score_gemma":0.00003404361,"teacher_disagreement_score":0.08634592,"about_ca_system_score_codex":0.00007601417,"about_ca_system_score_gemma":0.00007518886,"threshold_uncertainty_score":0.9998021},"labels":[],"label_agreement":null},{"id":"W2339075430","doi":"10.1124/mol.57.4.753","title":"Molecular Cloning and Characterization of a Lysophosphatidic Acid Receptor, Edg-7, Expressed in Prostate","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":199,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute; University of Virginia","keywords":"Lysophosphatidic acid; Cloning (programming); Receptor; Molecular cloning; Characterization (materials science); Chemistry; Biochemistry; Biology; Cell biology; Computational biology; Molecular biology; Gene; Peptide sequence; Computer science; Nanotechnology; Materials science","score_opus":0.004147974553608864,"score_gpt":0.23471021670726042,"score_spread":0.23056224215365156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2339075430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957819,0.0026776232,0.0006467103,0.0001318491,0.00016702632,0.00034405757,0.00002270963,0.000013628591,0.00021449056],"genre_scores_gemma":[0.9969545,0.0013136757,0.000458841,0.0008163869,0.000079769314,0.000071879294,0.0001835533,0.000037027436,0.000084388084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859935,0.0001863167,0.0003475291,0.0004296816,0.00011829765,0.00031880417],"domain_scores_gemma":[0.99954337,0.0000068672116,0.00011120823,0.00019222336,0.000056309593,0.000090044494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022008788,0.00019936069,0.0002716272,0.00009865026,0.000038776667,0.000013681245,0.00015743318,0.00013493547,0.00018608726],"category_scores_gemma":[0.000021319604,0.00022114064,0.000065447675,0.00018884244,0.00010244714,0.00001035803,0.000071179325,0.00012102345,0.000005380787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026638046,0.000076086755,0.0005367047,0.000037057864,0.000048170237,0.000032960026,0.00017171749,0.0002016993,0.9935193,0.00004173441,0.000038060756,0.0050300956],"study_design_scores_gemma":[0.0017602904,0.00011857371,0.0007922626,0.000019863488,0.000036785492,0.000011272139,0.000012957087,0.00021823129,0.9870761,0.00003142519,0.009718455,0.00020375167],"about_ca_topic_score_codex":0.000015034841,"about_ca_topic_score_gemma":7.406714e-7,"teacher_disagreement_score":0.009680394,"about_ca_system_score_codex":0.000008994603,"about_ca_system_score_gemma":0.000057028185,"threshold_uncertainty_score":0.9017853},"labels":[],"label_agreement":null},{"id":"W2343195587","doi":"10.1124/mol.60.6.1181","title":"Amphetamine, 3,4-Methylenedioxymethamphetamine, Lysergic Acid Diethylamide, and Metabolites of the Catecholamine Neurotransmitters Are Agonists of a Rat Trace Amine Receptor","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":643,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Lysergic acid diethylamide; Chemistry; Amphetamine; Pharmacology; Amine gas treating; Catecholamine; Biogenic amine; Receptor; Biochemistry; Neurotransmitter; Dopamine; Endocrinology; Biology; Serotonin; Organic chemistry","score_opus":0.018988790361716582,"score_gpt":0.279349511825649,"score_spread":0.2603607214639324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2343195587","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99261403,0.0016062919,0.00050633866,0.0021172347,0.001667214,0.0012207492,0.000075744705,0.0000941077,0.00009829695],"genre_scores_gemma":[0.995275,0.0010568578,0.00046745213,0.002500246,0.00005979709,0.00018058467,0.000003707793,0.000100149075,0.00035617812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9953301,0.0011967795,0.0009943746,0.0010477544,0.000687489,0.0007435244],"domain_scores_gemma":[0.9977958,0.000334725,0.00070484524,0.00076121173,0.00017584211,0.0002275779],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037052413,0.00059500674,0.0009423728,0.00032582672,0.00015097392,0.000032604607,0.0011728265,0.00020885612,0.0002343769],"category_scores_gemma":[0.00029802116,0.0004875147,0.0003930321,0.0014908446,0.0013703135,0.00028123826,0.00023283936,0.00061660283,0.000012766642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023212613,0.00039418103,0.004438019,0.00013526678,0.000040199135,0.00015859785,0.00022394069,0.00006732828,0.9913098,0.00008267684,0.00014766907,0.0027701803],"study_design_scores_gemma":[0.0021143295,0.0002411015,0.008977313,0.000037588696,0.00028690285,0.00019218471,0.000028876859,0.00006707835,0.9801056,0.00004344568,0.0075191515,0.00038646808],"about_ca_topic_score_codex":0.000037270736,"about_ca_topic_score_gemma":0.0000061823403,"teacher_disagreement_score":0.011204256,"about_ca_system_score_codex":0.00003843085,"about_ca_system_score_gemma":0.00006695482,"threshold_uncertainty_score":0.99975765},"labels":[],"label_agreement":null},{"id":"W2345106043","doi":"10.1124/mol.58.2.247","title":"Dual Expression and Differential Regulation of Phosphodiesterase 3A and Phosphodiesterase 3B in Human Vascular Smooth Muscle: Implications for Phosphodiesterase 3 Inhibition in Human Cardiovascular Tissues","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Phosphodiesterase 3; Phosphodiesterase; Milrinone; Cell biology; Cyclic nucleotide phosphodiesterase; PDE10A; Biology; Vascular smooth muscle; Endocrinology; Internal medicine; Pharmacology; Biochemistry; Enzyme; Medicine; Smooth muscle; Inotrope","score_opus":0.010360642266388326,"score_gpt":0.2755149560095104,"score_spread":0.2651543137431221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2345106043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918352,0.003596503,0.0028303743,0.00016205733,0.00015598767,0.0012413864,0.00006972054,0.000028409439,0.00008040093],"genre_scores_gemma":[0.9971041,0.0007715099,0.00041282497,0.00023627633,0.00011541533,0.0004205073,0.00076363515,0.00005922288,0.00011649289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99738836,0.00034854724,0.0007386242,0.00088903593,0.00018784514,0.0004475816],"domain_scores_gemma":[0.9990421,0.00004055983,0.00018654963,0.00045565603,0.0001241388,0.00015099117],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045166432,0.00041558978,0.00058232865,0.00023503137,0.00023005708,0.00004402037,0.00009869957,0.00034597536,0.00012990712],"category_scores_gemma":[0.000029622288,0.00044641303,0.00021853956,0.00019473534,0.00029733725,0.00004825187,0.0001339861,0.00018299284,0.0000010054229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032066277,0.000312551,0.002246911,0.00013477303,0.000111337,0.000017124285,0.00033474126,0.0010451991,0.9830245,0.00011054496,0.00025672215,0.012084937],"study_design_scores_gemma":[0.008144853,0.00043817158,0.09765533,0.00011983117,0.00020105946,0.000024163117,0.00006511525,0.00042212673,0.8829436,0.00053980964,0.008870507,0.0005754641],"about_ca_topic_score_codex":0.00015974157,"about_ca_topic_score_gemma":0.00007438058,"teacher_disagreement_score":0.10008093,"about_ca_system_score_codex":0.000062373816,"about_ca_system_score_gemma":0.00003983919,"threshold_uncertainty_score":0.9997988},"labels":[],"label_agreement":null},{"id":"W2396088443","doi":"10.1124/mol.58.6.1175","title":"Receptor Binding and Agonist Efficacy: New Insights from Mutants of the Thrombin Protease-Activated Receptor-1 (PAR-1)","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Protease-activated receptor 2; Thrombin; Thrombin receptor; Receptor; Agonist; Protease-activated receptor; Protease; Mutant; Ligand (biochemistry); Chemistry; Biochemistry; Cell biology; Biology; Molecular biology; 5-HT5A receptor; Enzyme; Gene; Immunology","score_opus":0.019848168029541337,"score_gpt":0.27964327050490345,"score_spread":0.25979510247536214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2396088443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951541,0.00028253638,0.000059594568,0.0019461836,0.00046545462,0.0009953397,0.000022635375,0.000068527566,0.0010056284],"genre_scores_gemma":[0.9971344,0.00005899327,0.0007998769,0.0013527995,0.00010732045,0.000023094912,0.00005462434,0.000038861748,0.00043001267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985857,0.00025053797,0.00032400916,0.0003705709,0.00024153444,0.00022767551],"domain_scores_gemma":[0.99928343,0.000049736023,0.0001413279,0.00026745204,0.000051535968,0.00020653055],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007313551,0.00020955081,0.00040725822,0.000076639706,0.00013015074,0.000014148582,0.00015165027,0.0001784434,0.00594922],"category_scores_gemma":[0.000031216172,0.00016199575,0.00010293176,0.00035667024,0.0001545858,0.0000510103,0.00006293122,0.00028136635,0.0001271254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029602353,0.0002838239,0.00014975121,0.000015945361,0.00028665143,0.000014177877,0.00026325177,0.0000068967693,0.9914432,0.00012813226,0.0021804892,0.004931615],"study_design_scores_gemma":[0.004613133,0.00023232332,0.0037016536,0.000074452975,0.00027493236,0.000016104079,0.00002317237,0.00008039595,0.98275816,0.00019811108,0.007872301,0.00015523614],"about_ca_topic_score_codex":0.00009397321,"about_ca_topic_score_gemma":0.0000019793695,"teacher_disagreement_score":0.008685057,"about_ca_system_score_codex":0.000045984416,"about_ca_system_score_gemma":0.00015809278,"threshold_uncertainty_score":0.9949595},"labels":[],"label_agreement":null},{"id":"W2399045176","doi":"10.1124/mol.115.102731","title":"Mechanisms of Action of Novel Influenza A/M2 Viroporin Inhibitors Derived from Hexamethylene Amiloride","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Amantadine; Rimantadine; Adamantane; Stereochemistry; Chemistry; Docking (animal); In vitro; Lead compound; Carboxylate; Influenza A virus; Virology; Biology; Virus; Biochemistry; Medicine","score_opus":0.08884217131705041,"score_gpt":0.40039437544841094,"score_spread":0.31155220413136053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2399045176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9653393,0.0005009207,0.032408625,0.0005528556,0.00042266262,0.0005008075,0.00007234301,0.000042043222,0.00016046026],"genre_scores_gemma":[0.9944517,0.00019956699,0.0038730907,0.001219329,0.00010081137,0.00006420791,0.0000056972026,0.00003755282,0.00004803051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981361,0.00014944281,0.0005412387,0.00034754316,0.00045386542,0.00037180333],"domain_scores_gemma":[0.9987189,0.00023357861,0.00026439384,0.00028790472,0.00035332527,0.0001419096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029148624,0.00021205898,0.0005675883,0.00026995962,0.000040337964,0.0000021051883,0.00015640714,0.00015710945,0.0003439816],"category_scores_gemma":[0.0003302021,0.00015869088,0.00016514915,0.00024069616,0.00034809977,0.000078952835,0.0002120331,0.00019937102,0.00002297191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011485606,0.0003293725,0.0005826437,0.00007705826,0.00062709436,0.00005103779,0.00010725156,0.00002970877,0.9923836,0.00017958273,0.00026523983,0.0042188284],"study_design_scores_gemma":[0.006985885,0.0005354444,0.0044591064,0.000074129595,0.00023755526,0.000005741823,0.00006537871,0.000047175523,0.985244,0.00037724292,0.0018316099,0.00013673281],"about_ca_topic_score_codex":0.0003118564,"about_ca_topic_score_gemma":0.000006600139,"teacher_disagreement_score":0.02911243,"about_ca_system_score_codex":0.00014889124,"about_ca_system_score_gemma":0.00014775319,"threshold_uncertainty_score":0.64712256},"labels":[],"label_agreement":null},{"id":"W2406525517","doi":"10.1124/mol.115.098509","title":"PDZ Protein Regulation of G Protein–Coupled Receptor Trafficking and Signaling Pathways","year":2015,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; Postsynaptic density; Guanylate kinase; Cell biology; G protein-coupled receptor; Scaffold protein; Biology; Protein kinase A; Membrane protein; Transport protein; Signal transduction; Biochemistry; Receptor; Kinase; Postsynaptic potential","score_opus":0.032189803456919325,"score_gpt":0.3044668203002467,"score_spread":0.2722770168433274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2406525517","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.029093921,0.9642263,0.0036141197,0.000014287369,0.00037737115,0.0025222427,0.000039937306,0.000032428296,0.00007937735],"genre_scores_gemma":[0.022033101,0.966541,0.0071302126,0.00009026829,0.0012106256,0.001153205,0.001139816,0.0003215277,0.0003802635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99705464,0.0005884025,0.00082569715,0.00080998056,0.00028281458,0.00043846772],"domain_scores_gemma":[0.998513,0.0000167808,0.00070963585,0.00033221117,0.00023771958,0.00019069108],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008176571,0.00055949425,0.0012898326,0.0001868304,0.000083234714,0.00002834116,0.0003330508,0.000781574,0.00023151611],"category_scores_gemma":[0.00006370938,0.0005315718,0.00037496822,0.00021295137,0.00012075289,0.0000067198357,0.00022177177,0.00034254324,0.000009808503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044510187,0.00005549789,6.900813e-8,0.0026575837,0.0002609807,0.000010533593,0.000029849698,0.000048861857,0.87357706,0.00012936551,0.00013262601,0.123053074],"study_design_scores_gemma":[0.00057773245,0.00038767638,2.984728e-8,0.0011611306,0.00037668267,0.000025037272,0.000014007109,0.000100319194,0.5075319,0.00006258675,0.4893115,0.00045145076],"about_ca_topic_score_codex":0.000005274105,"about_ca_topic_score_gemma":5.151659e-7,"teacher_disagreement_score":0.48917887,"about_ca_system_score_codex":0.000055483288,"about_ca_system_score_gemma":0.0004448956,"threshold_uncertainty_score":0.9997136},"labels":[],"label_agreement":null},{"id":"W2410915340","doi":"10.1124/mol.57.3.485","title":"Inhibition of c-<i>myc</i>Expression in Cells by Targeting an RNA-Protein Interaction Using Antisense Oligonucleotides","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Messenger RNA; Molecular biology; Oligonucleotide; RNA; Protein biosynthesis; Translation (biology); In vitro; Biology; Chemistry; Biochemistry; Gene","score_opus":0.009704535308287634,"score_gpt":0.3017023740159216,"score_spread":0.29199783870763396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410915340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99803424,0.00036748592,0.0009651743,0.000036744736,0.00007548301,0.00028033063,0.000013882971,0.000010551046,0.00021613248],"genre_scores_gemma":[0.99792844,0.000136054,0.001374946,0.00022226962,0.00007301547,0.000015189123,0.00010067643,0.00002947501,0.00011993269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848896,0.00035958385,0.0003117942,0.00036030082,0.00013369354,0.00034567385],"domain_scores_gemma":[0.9995798,0.000008098215,0.0000965038,0.00015370961,0.00005697578,0.00010489933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002624338,0.00015207317,0.000175931,0.0000999506,0.000059571925,0.000014197232,0.00011541137,0.0001426812,0.00023935105],"category_scores_gemma":[0.000017532871,0.00016430109,0.000065576634,0.00013182205,0.00007524515,0.000019637337,0.00006159605,0.00018090139,0.000006828603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032323258,0.00016675364,0.00006847471,0.000025757869,0.00001634506,0.00005741895,0.000033320823,0.0026699353,0.99388355,0.0000011260371,0.0006190913,0.0021349655],"study_design_scores_gemma":[0.00090727466,0.00024828291,0.00002005106,0.000035008816,0.0000097259635,0.000010026648,0.000048828406,0.004040078,0.9934012,0.0000114347395,0.0011130662,0.00015499177],"about_ca_topic_score_codex":0.00014127781,"about_ca_topic_score_gemma":0.0000065688814,"teacher_disagreement_score":0.0019799739,"about_ca_system_score_codex":0.000029994442,"about_ca_system_score_gemma":0.000039344333,"threshold_uncertainty_score":0.67000043},"labels":[],"label_agreement":null},{"id":"W2414017282","doi":"10.1124/mol.59.2.212","title":"Changes in Agonist Concentration Dependence That Are a Function of Duration of Exposure Suggest<i>N</i>-Methyl-d-aspartate Receptor Nonsaturation during Synaptic Stimulation","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Agonist; NMDA receptor; AMPA receptor; Glutamate receptor; Chemistry; Receptor; Partial agonist; Stimulation; Potency; Pharmacology; Intrinsic activity; Biophysics; Internal medicine; Endocrinology; Biology; Biochemistry; In vitro; Medicine","score_opus":0.03724894940386772,"score_gpt":0.31813652412468485,"score_spread":0.28088757472081716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414017282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972332,0.000080082806,0.00039307371,0.00068762334,0.0006921808,0.00081552647,0.000012422414,0.000041938565,0.000043968237],"genre_scores_gemma":[0.99874353,0.0005435842,0.000025313922,0.0004692928,0.00004594553,0.0000982495,0.0000071519958,0.000020510937,0.000046437402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99717826,0.00090590527,0.00045719277,0.00057917245,0.00046302585,0.0004164237],"domain_scores_gemma":[0.9988579,0.0002636068,0.00048177183,0.00017631044,0.00013543275,0.00008497384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003575928,0.00019593343,0.00029216084,0.0003058588,0.00014246888,0.000023123115,0.00025602742,0.00013165327,0.00016038728],"category_scores_gemma":[0.00026263404,0.00020605105,0.000058374073,0.00088723196,0.00029479977,0.00039478866,0.00006894653,0.00032050605,0.000013990921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011763403,0.00020622154,0.0146850245,0.000064387095,0.000008116127,0.00017898472,0.00014035859,0.003339385,0.97972244,0.000041568477,0.000016169737,0.0004210081],"study_design_scores_gemma":[0.001609509,0.0005464086,0.029551757,0.000024608893,0.000035862333,0.000037771122,0.00004031925,0.004880603,0.9630581,0.000029910136,0.000040562267,0.00014459179],"about_ca_topic_score_codex":0.000014140474,"about_ca_topic_score_gemma":0.000040893185,"teacher_disagreement_score":0.01666434,"about_ca_system_score_codex":0.000074275515,"about_ca_system_score_gemma":0.00008398899,"threshold_uncertainty_score":0.8402518},"labels":[],"label_agreement":null},{"id":"W2418742902","doi":"10.1016/s0026-895x(24)26491-9","title":"The Guanine Nucleotide Exchange Factor RasGRP Is a High -Affinity Target for Diacylglycerol and Phorbol Esters","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Protein kinase C; Diacylglycerol kinase; Chemistry; Phorbol; Guanine; Activator (genetics); Biochemistry; Receptor; Ligand (biochemistry); Nucleotide; Signal transduction; Gene","score_opus":0.0073673657391133485,"score_gpt":0.2559513224947824,"score_spread":0.24858395675566908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2418742902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921882,0.002174885,0.0030530554,0.0011245986,0.00044382346,0.0006816122,0.00010215035,0.000023291206,0.00020837528],"genre_scores_gemma":[0.99230736,0.0011621995,0.0012178129,0.0034512312,0.00034091418,0.00021413872,0.00007545467,0.000058327674,0.0011725783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984768,0.00014826747,0.00023874594,0.0004787627,0.0001137655,0.0005436697],"domain_scores_gemma":[0.99939644,0.000050524402,0.00007916407,0.00023939967,0.00006624972,0.00016823012],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024534826,0.00025104085,0.00022936038,0.000030501444,0.00028165587,0.000049947295,0.00026007052,0.00017372721,0.0018989631],"category_scores_gemma":[0.00002978137,0.00020554231,0.0001439026,0.000064541324,0.00011444097,0.0000057766297,0.00009383367,0.00012582855,0.000017279957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035836335,0.000047042024,0.000038101887,0.000018645556,0.00016617948,0.000009851138,0.00009272686,0.000046667185,0.9786043,0.000045274337,0.006846477,0.013726349],"study_design_scores_gemma":[0.0014372508,0.0004490972,0.000071109745,0.0000027733881,0.000051259256,0.000010004784,0.000019566713,0.0003034021,0.7745022,0.00022598826,0.22271709,0.00021023574],"about_ca_topic_score_codex":0.000022175329,"about_ca_topic_score_gemma":0.0000047486983,"teacher_disagreement_score":0.2158706,"about_ca_system_score_codex":0.000017151846,"about_ca_system_score_gemma":0.00004447255,"threshold_uncertainty_score":0.9990134},"labels":[],"label_agreement":null},{"id":"W2436697353","doi":"10.1124/mol.116.103648","title":"Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"HEK 293 cells; HeLa; Biochemistry; Molecular biology; Phosphorylation; Glycosylation; Biology; Chemistry; Cell; Gene","score_opus":0.005161295655220355,"score_gpt":0.24666168121277116,"score_spread":0.2415003855575508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2436697353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9604412,0.0023623367,0.03384033,0.0011989411,0.000102519996,0.0013855172,0.0001854102,0.000052698837,0.00043107112],"genre_scores_gemma":[0.9943608,0.00041704028,0.0013602983,0.00026354723,0.000022155138,0.00010418129,0.00008700624,0.000053417432,0.003331558],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978929,0.00011341677,0.0006668664,0.0005427633,0.00042556823,0.00035844286],"domain_scores_gemma":[0.998947,0.00004490709,0.00036811855,0.00021877476,0.0002551378,0.00016604601],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003217398,0.00029142978,0.0006266526,0.00015270637,0.000062425075,0.0000026481046,0.00011857531,0.00025208635,0.00023919993],"category_scores_gemma":[0.000021959673,0.00023747828,0.00015519667,0.00032379432,0.00022770184,0.000109496694,0.000011333574,0.00018816187,0.000005912503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033062939,0.00036838537,0.00046498183,0.00025504158,0.0002305208,0.00004494761,0.00030310208,0.0000055814025,0.99233806,0.00043811655,0.00079995004,0.0014450416],"study_design_scores_gemma":[0.0074939895,0.00036127522,0.0015082356,0.00016367967,0.00036060205,0.0000074990567,0.000022312312,0.00014104125,0.9851689,0.00049266237,0.0040391223,0.00024068049],"about_ca_topic_score_codex":0.000054468084,"about_ca_topic_score_gemma":0.000013788209,"teacher_disagreement_score":0.033919618,"about_ca_system_score_codex":0.00008512588,"about_ca_system_score_gemma":0.00016046914,"threshold_uncertainty_score":0.96840835},"labels":[],"label_agreement":null},{"id":"W2462337848","doi":"10.1124/mol.115.102418","title":"Latonduine Analogs Restore F508del–Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Cystic fibrosis transmembrane conductance regulator; Polymerase; Poly ADP ribose polymerase; Chloride channel; Endoplasmic reticulum; Biology; Chemistry; Molecular biology; Biochemistry; Cell biology; Enzyme; Gene","score_opus":0.017010440696951297,"score_gpt":0.31795293083052445,"score_spread":0.30094249013357316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2462337848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9567102,0.017208299,0.010509721,0.013415305,0.00041051037,0.0012140608,0.00027826952,0.00012358608,0.00013001617],"genre_scores_gemma":[0.9964796,0.00034155505,0.0013129028,0.00084749266,0.00040474607,0.00011512519,0.000046803674,0.000102655955,0.00034915598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958069,0.00072774605,0.00072919414,0.00096040353,0.0008012865,0.0009744907],"domain_scores_gemma":[0.9973309,0.000840193,0.00038636703,0.0007727237,0.00023481855,0.00043499426],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046791387,0.0005535464,0.00095440977,0.00028771456,0.000280502,0.000030566633,0.00036221187,0.00027745892,0.00057366665],"category_scores_gemma":[0.00037353789,0.0003848003,0.00027541773,0.0007142275,0.0012853842,0.00045353436,0.00014070189,0.00050827477,0.000012273051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033883261,0.000385305,0.0003444955,0.00026748198,0.00035646395,0.00022339997,0.0003310498,0.000042877506,0.9640651,0.00026731926,0.0007446236,0.029583555],"study_design_scores_gemma":[0.008010191,0.00091182103,0.007741044,0.00027201703,0.0005423471,0.00028654712,0.00007247315,0.0015050456,0.97664946,0.000307018,0.0032613075,0.00044075112],"about_ca_topic_score_codex":0.00041153253,"about_ca_topic_score_gemma":0.00004158947,"teacher_disagreement_score":0.03976933,"about_ca_system_score_codex":0.0002681013,"about_ca_system_score_gemma":0.00033574845,"threshold_uncertainty_score":0.9998604},"labels":[],"label_agreement":null},{"id":"W2463444379","doi":"10.1124/mol.57.4.725","title":"Antisense Inhibition of δ-Opioid Receptor Gene Function In Vivo by Peptide Nucleic Acids","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Réseau Technoscience; McGill University; AstraZeneca (Canada)","funders":"","keywords":"Peptide nucleic acid; Oligonucleotide; In vivo; Nucleic acid; Receptor; Agonist; Peptide; Biochemistry; Biology; δ-opioid receptor; Molecular biology; Chemistry; DNA","score_opus":0.0036734003886797094,"score_gpt":0.22584569248728803,"score_spread":0.2221722920986083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2463444379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99580616,0.000772417,0.00025823517,0.000103533595,0.00018146583,0.00017545206,0.00006792404,0.000019399904,0.0026154276],"genre_scores_gemma":[0.9963871,0.0006185364,0.00029187487,0.00096279377,0.00013637419,0.000029647941,0.00026748612,0.000038444115,0.0012677168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987252,0.000097196425,0.00031894894,0.00041952718,0.00012563038,0.00031354974],"domain_scores_gemma":[0.9995409,0.000006155388,0.000088732115,0.00022406824,0.00004908045,0.00009103795],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011723195,0.0001993925,0.00021238497,0.000051936073,0.000036560126,0.0000065634363,0.00012998549,0.00026534754,0.0021638991],"category_scores_gemma":[0.000010290875,0.00022944866,0.000106902364,0.00014787834,0.00013067473,0.0000064625665,0.000054490272,0.00014274947,0.000040135314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040226243,0.00019278262,0.0003703827,0.000028456698,0.0000563916,0.000024838222,0.000026217773,0.000059324146,0.9698454,0.0000034802229,0.027327057,0.0016633894],"study_design_scores_gemma":[0.0014138212,0.00023868463,0.00010054646,0.000008748546,0.00003759377,0.00001977829,0.000016169888,0.00003600114,0.91280097,0.000021537504,0.08510524,0.00020092599],"about_ca_topic_score_codex":0.000014781778,"about_ca_topic_score_gemma":0.0000018305356,"teacher_disagreement_score":0.057778183,"about_ca_system_score_codex":0.00002717059,"about_ca_system_score_gemma":0.00004509999,"threshold_uncertainty_score":0.99874824},"labels":[],"label_agreement":null},{"id":"W2469696470","doi":"10.1124/mol.116.104018","title":"Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Sigma-1 receptor; Mutant; Endoplasmic reticulum; Biology; Cell biology; Point mutation; Phenotype; Amyotrophic lateral sclerosis; Mutation; Chaperone (clinical); Receptor; Genetics; Gene; Medicine","score_opus":0.014679734556027247,"score_gpt":0.2824343635078096,"score_spread":0.26775462895178237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2469696470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9567958,0.0011751936,0.03934541,0.0007099593,0.0010811762,0.0004931322,0.00013501443,0.000048364644,0.0002159533],"genre_scores_gemma":[0.9975095,0.0005406303,0.00038545602,0.00094758236,0.00014103108,0.000082074206,0.00010764622,0.00006512572,0.00022097255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99761057,0.0004079749,0.00040038346,0.0006927137,0.00027039033,0.0006179431],"domain_scores_gemma":[0.99892706,0.00007706124,0.00019970028,0.0003601079,0.00013079568,0.00030529374],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023917454,0.00035106836,0.0004040682,0.00009707154,0.00008855022,0.000010949808,0.0004665654,0.00026080143,0.00078901736],"category_scores_gemma":[0.0001395747,0.0002664257,0.00031138156,0.00018129079,0.00023651044,0.000009861079,0.00027386,0.00013436959,0.00004128714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031948555,0.0002480124,0.00029476668,0.000045305314,0.00022419103,0.000094938194,0.0000070733477,0.00008407583,0.98869884,0.00045606797,0.0015918071,0.007935416],"study_design_scores_gemma":[0.002182907,0.0007879306,0.0002816626,0.000021988186,0.00016922598,0.000018438679,0.000011468447,0.00036209697,0.98593783,0.0004295334,0.009424411,0.0003725096],"about_ca_topic_score_codex":0.0000063797597,"about_ca_topic_score_gemma":0.0000025775419,"teacher_disagreement_score":0.040713683,"about_ca_system_score_codex":0.00006235447,"about_ca_system_score_gemma":0.00010186221,"threshold_uncertainty_score":0.9999788},"labels":[],"label_agreement":null},{"id":"W2501335509","doi":"10.1124/mol.116.104687","title":"A Fibroblast Growth Factor 21–Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Pregnane X receptor; CYP3A4; Nonalcoholic fatty liver disease; FGF21; Pregnane; Internal medicine; Endocrinology; Receptor; Fibroblast growth factor; Fatty liver; Chemistry; Disease; Biology; Medicine; Gene; Biochemistry; Nuclear receptor; Transcription factor; Metabolism; Cytochrome P450; Stereochemistry","score_opus":0.011037785506704046,"score_gpt":0.2644770787828422,"score_spread":0.2534392932761382,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2501335509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99534255,0.000855297,0.0011934804,0.0011104163,0.00018420788,0.00083756197,0.00026631413,0.00005265425,0.00015749024],"genre_scores_gemma":[0.99743104,0.000294764,0.00033790182,0.00060030207,0.0002164683,0.00026789552,0.00013752717,0.00010455885,0.00060956576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964969,0.0005742286,0.00046316162,0.0010303773,0.00038808124,0.0010472476],"domain_scores_gemma":[0.99852234,0.00008468097,0.0001311071,0.00053466205,0.00018496692,0.00054222444],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019722916,0.00048249224,0.00038142977,0.00026905327,0.000085302265,0.000032660882,0.0006474583,0.0003031599,0.0011739545],"category_scores_gemma":[0.00023567585,0.00039023574,0.00024818766,0.00030798628,0.0003761165,0.000023149925,0.0005341437,0.00025450165,0.0003880203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055836886,0.00026915182,0.009962768,0.00012630153,0.00012786628,0.00027114153,0.000041199888,0.000020673704,0.98558074,0.00008527516,0.0015111159,0.0014454154],"study_design_scores_gemma":[0.002595662,0.00043328025,0.036950964,0.00015466465,0.000021992313,0.00002027288,0.0000045182496,0.00008067964,0.9552768,0.000098397024,0.003819611,0.0005431917],"about_ca_topic_score_codex":0.000053094787,"about_ca_topic_score_gemma":0.000038640042,"teacher_disagreement_score":0.030303955,"about_ca_system_score_codex":0.00013746246,"about_ca_system_score_gemma":0.00028746625,"threshold_uncertainty_score":0.999855},"labels":[],"label_agreement":null},{"id":"W2506989837","doi":"10.1124/mol.116.105494","title":"AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Stress granule; Cell biology; EIF4E; AMPK; Signal transduction; Protein kinase A; Kinase; Acetylation; Phosphorylation; Eukaryotic initiation factor; Chemistry; Biology; Translation (biology); Biochemistry; Messenger RNA","score_opus":0.00665406836735796,"score_gpt":0.24087657597676312,"score_spread":0.23422250760940516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2506989837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9776279,0.006680232,0.014991324,0.00010530024,0.0002334421,0.00025283475,0.00003378959,0.000024025501,0.00005114798],"genre_scores_gemma":[0.99652594,0.0015316857,0.000355366,0.0010235069,0.00021916177,0.000034072502,0.00017104378,0.00005395694,0.00008523475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986675,0.0001774879,0.00022019498,0.00047474515,0.00011733465,0.00034275683],"domain_scores_gemma":[0.99940246,0.000019934154,0.00014611345,0.00017743539,0.00013521215,0.00011882677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013759843,0.00021036335,0.0001798873,0.000056493936,0.00011038782,0.000027014852,0.00014281309,0.0001739087,0.000077404264],"category_scores_gemma":[0.00004404123,0.00018886024,0.000044957065,0.00012091414,0.000054078944,0.000014303738,0.00009171897,0.00007969549,0.00000879433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031093386,0.00006394491,0.00032518807,0.000029208433,0.000050741153,0.0000034669852,0.00003444732,0.00004823938,0.9835134,0.0000065371164,0.0013321872,0.014561554],"study_design_scores_gemma":[0.001476718,0.000076755445,0.00007603638,0.000014815747,0.00005519838,0.0000031669692,0.000017667975,0.00003735645,0.98673385,0.000019099434,0.011236684,0.00025264992],"about_ca_topic_score_codex":0.000016901053,"about_ca_topic_score_gemma":0.0000020903174,"teacher_disagreement_score":0.018898068,"about_ca_system_score_codex":0.000029581042,"about_ca_system_score_gemma":0.00005225146,"threshold_uncertainty_score":0.7701497},"labels":[],"label_agreement":null},{"id":"W2519198844","doi":"10.1124/mol.116.105940","title":"A Pluridimensional View of Biased Agonism","year":2016,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Functional selectivity; Effector; G protein-coupled receptor; Computational biology; Signal transduction; Biology; Signaling proteins; Drug discovery; Identification (biology); Receptor; Phenotype; Subcellular localization; Ligand (biochemistry); Agonism; Cell signaling; Cell biology; Neuroscience; Bioinformatics; Genetics; Gene; Political science; Ecology","score_opus":0.02400689174464857,"score_gpt":0.33999626678133876,"score_spread":0.31598937503669017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2519198844","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022226006,0.9953864,0.0023782242,0.000031471012,0.0009229225,0.00062207144,0.0001140867,0.0000150587975,0.000307458],"genre_scores_gemma":[0.00017517184,0.9975859,0.0005585341,0.00034928828,0.00037995644,0.0001527465,0.0003068562,0.00010598009,0.0003855968],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99752367,0.00046516265,0.0006981699,0.00067972427,0.00020603734,0.00042722776],"domain_scores_gemma":[0.9988187,0.000047108653,0.00046169,0.0004076665,0.0001200062,0.00014480777],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003137526,0.000495836,0.0012919299,0.00015521403,0.00005115629,0.0000080257205,0.00046794975,0.0006240773,0.0013384334],"category_scores_gemma":[0.000033100674,0.00037911226,0.0008492947,0.00013854644,0.00012581721,0.0000019664599,0.00028218777,0.00021249622,0.00009469162],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019511554,0.00006476101,4.529766e-8,0.0017652506,0.00052940415,0.000048255122,0.0000026345745,0.0000019913032,0.6832725,0.00018029156,0.0025107707,0.3116046],"study_design_scores_gemma":[0.00040117512,0.00016991344,2.1026667e-8,0.0010089502,0.00038405586,0.00006130698,6.5317187e-7,0.0000012462033,0.2510994,0.000040394192,0.7465286,0.00030425217],"about_ca_topic_score_codex":0.000002243774,"about_ca_topic_score_gemma":2.3428177e-7,"teacher_disagreement_score":0.74401784,"about_ca_system_score_codex":0.000029680854,"about_ca_system_score_gemma":0.0004741388,"threshold_uncertainty_score":0.99986607},"labels":[],"label_agreement":null},{"id":"W2534448389","doi":"10.1124/mol.116.105544","title":"Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Eye Institute","keywords":"Doxorubicin; Transporter; Organic anion-transporting polypeptide; Efflux; Pharmacology; HeLa; In vivo; Chemistry; In vitro; P-glycoprotein; Anthracycline; Organic cation transport proteins; Pharmacokinetics; Organic anion transporter 1; Biochemistry; Biology; Cancer; Multiple drug resistance; Gene; Chemotherapy","score_opus":0.006341631279563387,"score_gpt":0.26674391473504233,"score_spread":0.26040228345547894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2534448389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97416985,0.000691298,0.020695727,0.0035824736,0.00022990184,0.00043216837,0.000012036904,0.000051449068,0.0001351178],"genre_scores_gemma":[0.997485,0.00014120358,0.0007207035,0.0013705898,0.00006641591,0.000015435562,0.000007589406,0.00002629151,0.00016681371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988641,0.000035374636,0.0003460087,0.00028356767,0.00015771462,0.00031321234],"domain_scores_gemma":[0.9994291,0.000025440959,0.00009609013,0.00013186614,0.00014145936,0.00017600923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021966366,0.00014470165,0.000353326,0.000098306875,0.00004386359,0.0000026542193,0.0000715324,0.00009774623,0.0002655768],"category_scores_gemma":[0.000026210091,0.000105201965,0.000071727874,0.00018199712,0.00009074734,0.00003657277,0.00001445951,0.000092331284,0.000020724874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069113,0.000088586494,0.0029309036,0.000052844134,0.00010072123,0.00017945812,0.000086118795,0.0000014256842,0.9924368,0.0005968884,0.00010502099,0.0027300466],"study_design_scores_gemma":[0.0032568069,0.00035248982,0.02450293,0.00012896255,0.0002060234,0.000035527897,0.000026062084,0.000006212156,0.967692,0.00013463532,0.0035336765,0.00012467006],"about_ca_topic_score_codex":0.0000063646003,"about_ca_topic_score_gemma":0.000016884684,"teacher_disagreement_score":0.024744852,"about_ca_system_score_codex":0.000035346784,"about_ca_system_score_gemma":0.000054620046,"threshold_uncertainty_score":0.42900115},"labels":[],"label_agreement":null},{"id":"W2564137162","doi":"10.1124/mol.116.106161","title":"Cross-Talk between Alternatively Spliced UGT1A Isoforms and Colon Cancer Cell Metabolism","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Warburg effect; Glycolysis; PKM2; Biochemistry; Cell biology; Metabolism; Pyruvate kinase","score_opus":0.014954311082649222,"score_gpt":0.34069407746772584,"score_spread":0.3257397663850766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2564137162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787672,0.014847276,0.000494476,0.0003617487,0.0025469845,0.00043149482,0.00016782367,0.000022912738,0.0023600415],"genre_scores_gemma":[0.9876027,0.005410656,0.0002661931,0.0013710328,0.00280955,0.00016636396,0.00006478558,0.000062996885,0.0022456918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815863,0.00009113006,0.00029014924,0.00070600456,0.00017707713,0.00057703105],"domain_scores_gemma":[0.9987339,0.0000128655765,0.00031936084,0.00052769756,0.00014886948,0.00025731706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023559273,0.00033789346,0.00041912697,0.00004836218,0.00044034797,0.00012873726,0.00062769296,0.00028333828,0.00021994128],"category_scores_gemma":[0.000034653764,0.00033275143,0.00015885712,0.00003772877,0.00041516166,0.00002652364,0.00051310036,0.00021244273,0.000012584026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014863611,0.00005275734,0.0023433524,0.00003080551,0.00025116038,0.00001637218,0.000055462035,0.00002319294,0.98608816,0.00004744185,0.0020107,0.00893197],"study_design_scores_gemma":[0.002452506,0.00008446041,0.025631065,0.0000036448444,0.00019110592,0.000011404321,0.000008424896,0.000021573513,0.66109043,0.000052690673,0.3101589,0.00029376554],"about_ca_topic_score_codex":0.0008544866,"about_ca_topic_score_gemma":0.00012985892,"teacher_disagreement_score":0.3249977,"about_ca_system_score_codex":0.00002993193,"about_ca_system_score_gemma":0.00013627496,"threshold_uncertainty_score":0.99991244},"labels":[],"label_agreement":null},{"id":"W2564643151","doi":"10.1124/mol.116.107367","title":"Buprenorphine, Norbuprenorphine, R-Methadone, and S-Methadone Upregulate BCRP/ABCG2 Expression by Activating Aryl Hydrocarbon Receptor in Human Placental Trophoblasts","year":2016,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Environmental Health Sciences; National Institute on Drug Abuse; National Institutes of Health; University of Toronto; Teikyo University School of Medicine; University of Washington","keywords":"Aryl hydrocarbon receptor; Abcg2; Pharmacology; Opioid receptor; Buprenorphine; Agonist; Methadone; Opioid; Placenta; Chemistry; Receptor; Medicine; Endocrinology; Internal medicine; Fetus; Biology; Pregnancy; Transcription factor; ATP-binding cassette transporter; Transporter; Biochemistry","score_opus":0.006183553393284146,"score_gpt":0.25965094086429374,"score_spread":0.2534673874710096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2564643151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99310213,0.0023660173,0.0013039177,0.0010354613,0.0004716519,0.001173003,0.00003877489,0.00018914066,0.00031987787],"genre_scores_gemma":[0.9969265,0.00016470904,0.0013598255,0.0006130216,0.00020145769,0.00018565565,0.00008104251,0.00012847212,0.00033935392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965237,0.00038802932,0.000655343,0.0010528079,0.00047442518,0.00090571004],"domain_scores_gemma":[0.99845827,0.0003048559,0.00029076924,0.00043044676,0.00006478973,0.00045086694],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004585656,0.0005822296,0.0008344686,0.0003688132,0.00012135744,0.000020445152,0.00027661896,0.0003838848,0.00044608192],"category_scores_gemma":[0.0001500671,0.00046777382,0.00013759552,0.00044383877,0.00029055538,0.00028719692,0.00031635977,0.0006247816,0.000034431774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012539463,0.00039150793,0.006955084,0.0001122593,0.00012237068,0.00040918682,0.00018527571,0.000014985824,0.9800197,0.000014155455,0.0032549533,0.0072666123],"study_design_scores_gemma":[0.011896236,0.0007052206,0.008365247,0.00044062806,0.00008202831,0.00011112422,0.00001761297,0.00019447513,0.97654176,0.00008738468,0.0010566113,0.000501693],"about_ca_topic_score_codex":0.00008406437,"about_ca_topic_score_gemma":0.0000118542075,"teacher_disagreement_score":0.01064229,"about_ca_system_score_codex":0.00034543464,"about_ca_system_score_gemma":0.00006261523,"threshold_uncertainty_score":0.9997774},"labels":[],"label_agreement":null},{"id":"W2583065836","doi":"10.1124/mol.116.106526","title":"Targeting a Proteinase-Activated Receptor 4 (PAR4) Carboxyl Terminal Motif to Regulate Platelet Function","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Calgary; Western University","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cell biology; Thrombin; Receptor; Platelet; Platelet activation; Protease-activated receptor; Chemistry; Intracellular; G protein-coupled receptor; In vitro; Calcium in biology; Biochemistry; Pharmacology; Biology; Immunology","score_opus":0.022711615204321734,"score_gpt":0.3109650532940554,"score_spread":0.28825343808973364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583065836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872906,0.000052306157,0.004625272,0.0041722246,0.001226644,0.0013937658,0.000007023862,0.00016531076,0.0010668576],"genre_scores_gemma":[0.99317425,0.0000061493683,0.0026126886,0.0028778156,0.00032194037,0.00019093415,0.00005206252,0.000057038364,0.00070712715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836534,0.00012842884,0.0003067336,0.0004955149,0.00026085347,0.0004431018],"domain_scores_gemma":[0.99884105,0.000013239028,0.00022581557,0.00044414867,0.00016293518,0.00031282014],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027999733,0.00024582507,0.0003947787,0.00016198397,0.00036739433,0.000054096814,0.00020416071,0.0001904353,0.0011065406],"category_scores_gemma":[0.00010386327,0.00024530155,0.000106987434,0.00012274104,0.0000715736,0.00010978953,0.00014399472,0.00029892006,0.00023749204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069370394,0.00016631621,0.000117502146,0.000044321056,0.00021411727,0.0002649907,0.00007248753,0.000065451764,0.9900659,0.0002149036,0.0027723857,0.0053079263],"study_design_scores_gemma":[0.0029906635,0.0007373989,0.002524994,0.000047851783,0.00021927178,0.00006054936,0.000020370075,0.00101909,0.9730355,0.00014069575,0.018960211,0.00024339618],"about_ca_topic_score_codex":0.000046161134,"about_ca_topic_score_gemma":0.0000013651423,"teacher_disagreement_score":0.017030386,"about_ca_system_score_codex":0.00008883193,"about_ca_system_score_gemma":0.00008649636,"threshold_uncertainty_score":0.99999994},"labels":[],"label_agreement":null},{"id":"W2584155195","doi":"10.1124/mol.116.108035","title":"β-Arrestin-Mediated Regulation of the Human Ether-a-go-go-Related Gene Potassium Channel","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"hERG; HEK 293 cells; G protein-coupled receptor; Arrestin; Cell biology; Chemistry; Potassium channel; Signal transduction; Pharmacology; Receptor; Biology; Biochemistry; Endocrinology","score_opus":0.01330078029083944,"score_gpt":0.281600554282787,"score_spread":0.2682997739919476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2584155195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99457496,0.00038794355,0.0015623538,0.0006525021,0.0011542221,0.00036031374,0.000020208232,0.00001738999,0.0012700781],"genre_scores_gemma":[0.9981685,0.000026003818,0.00020935027,0.00040321477,0.00018626163,0.000031310297,0.000102761274,0.00004255739,0.00083001266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985491,0.00022874573,0.00033482097,0.00038936455,0.00018005217,0.00031793324],"domain_scores_gemma":[0.9986744,0.000011203591,0.00044274647,0.00064786756,0.0001379775,0.00008579306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032682504,0.00020773849,0.00022222036,0.000044898457,0.00040397543,0.00002559195,0.0006652395,0.00031157237,0.0003576615],"category_scores_gemma":[0.00007246948,0.0001737053,0.00018603411,0.000063981206,0.00023511503,0.0000059848912,0.00031244406,0.00019363771,0.000018737805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003274732,0.00006160615,0.00025349503,0.000011618523,0.0001620175,0.00000857929,0.00003967458,0.0006267084,0.9973433,0.00021877904,0.001036167,0.00020529727],"study_design_scores_gemma":[0.0011614931,0.00012953355,0.0032554753,0.000011214028,0.00009631529,0.000014367286,0.0000075680427,0.00062384264,0.99097395,0.00070676033,0.0028290348,0.00019042134],"about_ca_topic_score_codex":0.000031892287,"about_ca_topic_score_gemma":0.0000062527974,"teacher_disagreement_score":0.0063693356,"about_ca_system_score_codex":0.00001764686,"about_ca_system_score_gemma":0.00006884919,"threshold_uncertainty_score":0.70834965},"labels":[],"label_agreement":null},{"id":"W2592331661","doi":"10.1124/mol.116.106419","title":"Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"HEK 293 cells; Purinergic receptor; Transactivation; P2Y receptor; Receptor; Cell biology; Intracellular; Extracellular; Biology; Apyrase; G protein-coupled receptor; Gs alpha subunit; G protein; Signal transduction; Biochemistry; Gene expression","score_opus":0.0074310746962491115,"score_gpt":0.24668717315992442,"score_spread":0.2392560984636753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592331661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98697984,0.0018554878,0.008428746,0.00087001943,0.0008646603,0.00047664845,0.000044177927,0.000020434818,0.00045998057],"genre_scores_gemma":[0.99611825,0.0006778016,0.0005206653,0.0007987804,0.00031468505,0.00016911804,0.00021179767,0.00006045592,0.0011284304],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793315,0.00033116722,0.0003721836,0.00061111024,0.00020552249,0.0005468698],"domain_scores_gemma":[0.9989013,0.000036122165,0.0002506008,0.00058918964,0.000084430925,0.0001383363],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005101777,0.00031903898,0.00029268663,0.00007089703,0.0004002384,0.00010179272,0.00077590503,0.00029869933,0.0012823403],"category_scores_gemma":[0.000062507424,0.0002755655,0.00015574366,0.000094430674,0.0001794554,0.00002119141,0.00014417386,0.0002951354,0.00004409951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017223637,0.00018243001,0.0000642664,0.000015184834,0.000088292654,0.000017910079,0.000043439566,0.0016168554,0.9891568,0.000058236026,0.007087705,0.0014966604],"study_design_scores_gemma":[0.00134441,0.0001820467,0.0000204711,0.000011219752,0.000039464114,0.0000068588197,0.000037913807,0.00061934453,0.9178479,0.00004473999,0.079539485,0.00030616493],"about_ca_topic_score_codex":0.00045028885,"about_ca_topic_score_gemma":0.000029262565,"teacher_disagreement_score":0.07245178,"about_ca_system_score_codex":0.00004940853,"about_ca_system_score_gemma":0.000095291245,"threshold_uncertainty_score":0.99996966},"labels":[],"label_agreement":null},{"id":"W2605462363","doi":"10.1124/mol.116.107003","title":"Negative Regulation of Human Pregnane X Receptor by MicroRNA-18a-5p: Evidence for Suppression of MicroRNA-18a-5p Expression by Rifampin and Rilpivirine","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pregnane X receptor; microRNA; Regulator; Biology; Gene knockdown; Transfection; Gene expression; Cell biology; Regulation of gene expression; Molecular biology; Nuclear receptor; Gene; Transcription factor; Genetics","score_opus":0.021285458108580454,"score_gpt":0.3392361224968723,"score_spread":0.31795066438829184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605462363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98908675,0.0050982255,0.003649301,0.00037247964,0.00023706113,0.0011367335,0.00035406166,0.000013177114,0.00005222271],"genre_scores_gemma":[0.99650997,0.00038437272,0.0016557778,0.00009742599,0.000109271685,0.00012554337,0.00065468973,0.000056447345,0.00040651025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978985,0.00028114545,0.0005685994,0.000708172,0.00019511198,0.00034844648],"domain_scores_gemma":[0.9980216,0.000070928276,0.0007827124,0.0006639569,0.00031461322,0.00014620178],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032015878,0.0003212878,0.0004184179,0.00007948681,0.00026732634,0.000028723438,0.00049282704,0.00034596672,0.00009928184],"category_scores_gemma":[0.00021921753,0.00033029635,0.0001595679,0.000054073553,0.00050904125,0.000039433955,0.00037669204,0.000121420584,0.0000016923067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084758166,0.00019220439,0.0005602386,0.00026331365,0.00011988782,0.0000013048574,0.00006296321,0.000014902466,0.9591059,0.00001412205,0.038091682,0.0007258671],"study_design_scores_gemma":[0.002850402,0.0005164565,0.0016575617,0.000274354,0.00014731218,0.000005579445,0.000013135588,0.0000646402,0.9875691,0.00011555945,0.0064852405,0.00030065764],"about_ca_topic_score_codex":0.000042103988,"about_ca_topic_score_gemma":0.0000035707142,"teacher_disagreement_score":0.031606443,"about_ca_system_score_codex":0.000038041126,"about_ca_system_score_gemma":0.0000696188,"threshold_uncertainty_score":0.9999149},"labels":[],"label_agreement":null},{"id":"W2618831618","doi":"10.1124/mol.117.108373","title":"Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Cystic Fibrosis Canada; Vertex Pharmaceuticals; Cystic Fibrosis Foundation Therapeutics","keywords":"Allosteric regulation; Chemistry; Potentiator; Cyclic nucleotide-binding domain; Binding site; Cystic fibrosis transmembrane conductance regulator; Transmembrane domain; Stereochemistry; Biophysics; Crystallography; Nucleotide; Biochemistry; Membrane; Biology","score_opus":0.04436644329969548,"score_gpt":0.41460320951004376,"score_spread":0.3702367662103483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2618831618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99396527,0.0014401553,0.00036930587,0.0024270513,0.0003443542,0.0012917583,0.000023928478,0.000017040458,0.00012111465],"genre_scores_gemma":[0.99913526,0.00008047089,0.00024059197,0.00020098609,0.00011398221,0.000057021436,0.0000032227101,0.000030396972,0.00013807463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979637,0.0004512412,0.00039742136,0.0003618149,0.0004335744,0.00039220107],"domain_scores_gemma":[0.99732816,0.0012224222,0.0003894474,0.0007689243,0.0001480568,0.00014297264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016154228,0.0001977552,0.0005357834,0.00011039786,0.0005971886,0.000059046117,0.00091529783,0.00006447325,0.000060574286],"category_scores_gemma":[0.0013650152,0.00010640463,0.00012354311,0.00020681744,0.0011034069,0.00013363468,0.00085192634,0.0004368524,0.000009439433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059594394,0.00003201611,0.01207358,0.00012976483,0.00017182433,0.00001798522,0.0006335914,0.00016661776,0.9850659,0.000008766032,0.00018049368,0.0009235141],"study_design_scores_gemma":[0.0024733199,0.0006343392,0.02551358,0.00058926916,0.00043025124,0.000028293116,0.0001765472,0.00147309,0.9678734,0.000015317026,0.0006561376,0.0001364766],"about_ca_topic_score_codex":0.00019227221,"about_ca_topic_score_gemma":0.000032244003,"teacher_disagreement_score":0.017192524,"about_ca_system_score_codex":0.00007264315,"about_ca_system_score_gemma":0.00007608723,"threshold_uncertainty_score":0.4593152},"labels":[],"label_agreement":null},{"id":"W2745985563","doi":"10.1124/mol.117.109017","title":"Transforming Growth Factor-β1/Activin Receptor-like Kinase 5-Mediated Cell Migration is Dependent on the Protein Proteinase-Activated Receptor 2 but not on Proteinase-Activated Receptor 2-Stimulated Gq-Calcium Signaling","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; University of Calgary","keywords":"Autocrine signalling; Cell biology; Biology; SMAD; Receptor; Transforming growth factor; Signal transduction; R-SMAD; Cell migration; Protease-activated receptor 2; Motility; Growth factor; Cell; TGF alpha; Enzyme-linked receptor; Biochemistry","score_opus":0.022926344108443242,"score_gpt":0.27767930246262135,"score_spread":0.2547529583541781,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2745985563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98816764,0.00017977552,0.0011541782,0.002465598,0.0007019885,0.0063831266,0.0005584614,0.00022177721,0.00016747566],"genre_scores_gemma":[0.9930145,0.00003488723,0.00034057396,0.0019109489,0.00036450234,0.0022006298,0.0009620924,0.0002713745,0.00090049783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9939441,0.0011847933,0.000932268,0.001790549,0.0008764868,0.0012718086],"domain_scores_gemma":[0.99650055,0.00016270069,0.0010123291,0.0013398926,0.00054278347,0.00044175104],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00060103467,0.0011365379,0.0007236217,0.00026629266,0.0013096272,0.0002742916,0.0013851237,0.00090093387,0.0012073311],"category_scores_gemma":[0.0006862524,0.0009961171,0.00043932063,0.00028779078,0.00036522382,0.00007287675,0.0002578369,0.001115461,0.0003073265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005236654,0.0011855958,0.000060382383,0.00015317438,0.00048066408,0.00007145235,0.00021317367,0.0003429346,0.9897785,0.0000124692515,0.0015538201,0.00091113837],"study_design_scores_gemma":[0.0037867392,0.001725699,0.00006137335,0.00019994128,0.00011981689,0.0000042444976,0.00007298683,0.0002717079,0.98136264,0.00000981235,0.01125634,0.0011286909],"about_ca_topic_score_codex":0.00030097377,"about_ca_topic_score_gemma":0.000010068757,"teacher_disagreement_score":0.0097025195,"about_ca_system_score_codex":0.0003773947,"about_ca_system_score_gemma":0.0005219536,"threshold_uncertainty_score":0.9999905},"labels":[],"label_agreement":null},{"id":"W2747828488","doi":"10.1124/mol.117.108654","title":"Selective HIF-1 Regulation under Nonhypoxic Conditions by the p42/p44 MAP Kinase Inhibitor PD184161","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"MG132; Angiotensin II; Vascular smooth muscle; Cell biology; MAPK/ERK pathway; Activator (genetics); Chemistry; Endocrinology; Regulator; Internal medicine; Signal transduction; Biology; Receptor; Proteasome; Proteasome inhibitor; Biochemistry; Medicine; Gene","score_opus":0.00926098800535438,"score_gpt":0.29366415541485474,"score_spread":0.2844031674095004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2747828488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9760876,0.0055154893,0.0030884007,0.005938704,0.0051314705,0.00088310847,0.0001946338,0.000044231932,0.0031163117],"genre_scores_gemma":[0.99038637,0.00022997093,0.000096774915,0.0036055623,0.0020442465,0.00020455016,0.00031674476,0.000051441697,0.0030643481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983453,0.00021762622,0.00024671142,0.00055397203,0.00018125177,0.00045513824],"domain_scores_gemma":[0.99874735,0.000020664413,0.00023599234,0.0006796783,0.00017119682,0.00014510694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000214678,0.00027118376,0.0002296141,0.000052088082,0.0007952743,0.00008385152,0.0005100434,0.00026176393,0.00021794233],"category_scores_gemma":[0.000053042524,0.00024242337,0.00018219565,0.00007429815,0.00044410254,0.000015424193,0.00022834585,0.0002491825,0.000087824366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082903796,0.00008377165,0.000043168184,0.000008088932,0.00016211747,0.000004095159,0.000024054238,0.000106686326,0.7994047,0.00029881005,0.19915985,0.0006217923],"study_design_scores_gemma":[0.0014139377,0.00010192761,0.0023035973,0.000004138282,0.00014096523,0.000022267293,0.00001964031,0.000065645,0.6818013,0.0005068275,0.3133865,0.0002332397],"about_ca_topic_score_codex":0.000073114265,"about_ca_topic_score_gemma":0.000054243083,"teacher_disagreement_score":0.11760335,"about_ca_system_score_codex":0.000049070823,"about_ca_system_score_gemma":0.00016461346,"threshold_uncertainty_score":0.98857385},"labels":[],"label_agreement":null},{"id":"W2760942798","doi":"10.1124/mol.117.110379","title":"RVX-297, a BET Bromodomain Inhibitor, Has Therapeutic Effects in Preclinical Models of Acute Inflammation and Autoimmune Disease","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Resverlogix (Canada)","funders":"","keywords":"Bromodomain; Experimental autoimmune encephalomyelitis; BRD4; Inflammation; BET inhibitor; Chromatin; Histone; Epigenetics; Proinflammatory cytokine; Chemistry; Ex vivo; Cancer research; Biology; Cell biology; Immunology; In vitro; Gene; Biochemistry","score_opus":0.021615671973866546,"score_gpt":0.32044416458969144,"score_spread":0.2988284926158249,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2760942798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99125147,0.0015860611,0.0047944007,0.001285767,0.0002777394,0.0006168323,0.0000144104415,0.000012106136,0.00016121773],"genre_scores_gemma":[0.9987198,0.00020188278,0.00039138488,0.00031546399,0.00009906631,0.00011083347,0.000066070956,0.000023524193,0.000071977025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986601,0.00027606924,0.0003376633,0.00037074095,0.00012440812,0.00023100268],"domain_scores_gemma":[0.999162,0.000023773908,0.00022742125,0.0004190041,0.000054055905,0.000113708025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003000145,0.0001781203,0.0002603099,0.00007574983,0.0001227023,0.00003907562,0.000269863,0.00018596955,0.000009976468],"category_scores_gemma":[0.0000811818,0.00018027297,0.00009775598,0.00004056524,0.00032856004,0.000021785163,0.00025550512,0.00014797632,0.0000024560006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048193123,0.000110881265,0.00079398847,0.000054985656,0.00014940857,0.00004666433,0.00004215793,0.0001230414,0.9937522,0.000438997,0.0001646361,0.0038411308],"study_design_scores_gemma":[0.003252872,0.00029413792,0.010279783,0.00003321947,0.000134516,0.00000652419,0.0000027982333,0.004351456,0.97787845,0.0023463052,0.0012139031,0.00020602025],"about_ca_topic_score_codex":0.00001737487,"about_ca_topic_score_gemma":0.0000052039,"teacher_disagreement_score":0.015873713,"about_ca_system_score_codex":0.000015170738,"about_ca_system_score_gemma":0.00010818311,"threshold_uncertainty_score":0.73513186},"labels":[],"label_agreement":null},{"id":"W2768658822","doi":"10.1124/mol.117.110007","title":"Molecular Imaging of GLUT1 and GLUT5 in Breast Cancer: A Multitracer Positron Emission Tomography Imaging Study in Mice","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"GLUT1; Glucose transporter; Positron emission tomography; Glucose uptake; Chemistry; Carbohydrate metabolism; Glucose Transporter Type 1; Fructose; Endocrinology; Internal medicine; Biochemistry; Biology; Medicine; Nuclear medicine; Insulin","score_opus":0.004987557512227157,"score_gpt":0.29635827651931573,"score_spread":0.29137071900708855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2768658822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830066,0.014550909,0.00012277672,0.0008525672,0.00064806547,0.0006016625,0.000035508372,0.000009196644,0.00017269104],"genre_scores_gemma":[0.99797547,0.000953918,0.00013952836,0.0005719884,0.00018284991,0.00010626672,0.000012301993,0.000041912204,0.000015788597],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981317,0.00021476674,0.0003725427,0.0006556452,0.00015943479,0.00046589196],"domain_scores_gemma":[0.99914205,0.000009288769,0.00022874218,0.0003994188,0.000092500755,0.00012799],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032971762,0.0002809905,0.000385725,0.00025055715,0.00010162948,0.000036567537,0.00039407978,0.000102343365,0.000017561279],"category_scores_gemma":[0.000023318215,0.00030641793,0.00011234809,0.00012898535,0.00020728847,0.000020437308,0.00035614448,0.00023451146,5.129697e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002791162,0.00027710325,0.24094221,0.000029723496,0.000060778482,0.000095200056,0.00013832543,0.000100630066,0.7514368,0.000003400108,0.00018025108,0.0064564543],"study_design_scores_gemma":[0.0062834052,0.00007034448,0.31868345,0.000051740193,0.00014193183,0.000072855626,0.0001755563,0.00074148073,0.6714635,0.000024728193,0.0019010254,0.00039000387],"about_ca_topic_score_codex":0.0018180038,"about_ca_topic_score_gemma":0.00025089632,"teacher_disagreement_score":0.079973325,"about_ca_system_score_codex":0.000033896835,"about_ca_system_score_gemma":0.00010835729,"threshold_uncertainty_score":0.9999388},"labels":[],"label_agreement":null},{"id":"W2793038282","doi":"10.1124/mol.117.110908","title":"Inhibition of CD45 Phosphatase Activity Induces Cell Cycle Arrest and Apoptosis of CD45+ Lymphoid Tumors Ex Vivo and In Vivo","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Programmed cell death; Apoptosis; Protein tyrosine phosphatase; Cancer research; Cell cycle; Biology; Cell growth; In vivo; Cell biology; Ex vivo; Kinase; Molecular biology; Chemistry; Biochemistry","score_opus":0.006319490177551973,"score_gpt":0.25312441367308786,"score_spread":0.24680492349553587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793038282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99355423,0.0052300603,0.00019706963,0.00007298603,0.00013773075,0.00038949575,0.00023327777,0.000008372794,0.00017676123],"genre_scores_gemma":[0.9988061,0.00039563756,0.00032150839,0.00027977146,0.00007209062,0.000043846856,0.000041321968,0.000026873378,0.0000128090305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857646,0.00016801503,0.00030868137,0.00047602734,0.00012463192,0.00034615636],"domain_scores_gemma":[0.9992817,0.00002654807,0.00023970005,0.00023703116,0.000089785586,0.00012520152],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024552862,0.00022814365,0.00031939326,0.00011526783,0.000045149936,0.000008833605,0.00013876933,0.00017861,0.00006882401],"category_scores_gemma":[0.000058312602,0.0002498977,0.000051779636,0.00017562088,0.0005457429,0.00001657943,0.00029664286,0.00009695081,0.000001628132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050023815,0.00026325943,0.00085464393,0.00011568558,0.00004042218,0.000017132523,0.000055598397,0.000016465188,0.9969833,0.00004397373,0.00055157003,0.00055774994],"study_design_scores_gemma":[0.0020969675,0.00054148876,0.0005634786,0.00002953547,0.00005519395,0.000014854759,0.000025064715,0.00007843739,0.99595666,0.000085032676,0.00033323286,0.00022005595],"about_ca_topic_score_codex":0.0002571395,"about_ca_topic_score_gemma":0.000032212418,"teacher_disagreement_score":0.005251895,"about_ca_system_score_codex":0.000022127992,"about_ca_system_score_gemma":0.00010081119,"threshold_uncertainty_score":0.99999535},"labels":[],"label_agreement":null},{"id":"W2795911726","doi":"10.1124/mol.118.111799","title":"Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Università degli Studi di Ferrara; University of Toronto; Cystic Fibrosis Canada","keywords":"Mutant; Cystic fibrosis transmembrane conductance regulator; Cyclic nucleotide-binding domain; Mutation; Allosteric regulation; Cystic fibrosis; Transmembrane domain; Mutant protein; Chemistry; Mutagenesis; Membrane protein; Cell biology; Biophysics; Biology; Biochemistry; Nucleotide; Membrane; Genetics; Receptor; Gene","score_opus":0.0134691017420625,"score_gpt":0.3422488310428042,"score_spread":0.3287797293007417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795911726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99024385,0.00050146296,0.004015649,0.0016127868,0.0012986965,0.00072912924,0.000026172671,0.000053007876,0.0015192268],"genre_scores_gemma":[0.9941402,0.000017156628,0.0034573367,0.0018388809,0.00022384588,0.000047887166,0.0000112823645,0.000040707215,0.0002227118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980784,0.00027019042,0.00037124328,0.00035397825,0.0004274086,0.00049875],"domain_scores_gemma":[0.99876606,0.000321452,0.00016107464,0.00038922828,0.0002288841,0.000133298],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020831608,0.00020603981,0.00040465596,0.00010086493,0.00012687857,0.00001137854,0.00034237726,0.000085455664,0.0011697401],"category_scores_gemma":[0.0004922376,0.0001449763,0.00019652072,0.00048885075,0.0007643541,0.00007876865,0.00025996534,0.00034638125,0.00008864235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084408344,0.00013121375,0.00052914437,0.0001284055,0.00023070608,0.00013309935,0.00045290164,0.00002975203,0.9942363,0.00008136645,0.0027724237,0.00043059664],"study_design_scores_gemma":[0.001973723,0.0007371143,0.0019165116,0.0001449094,0.00029711257,0.00020362118,0.00007473045,0.0008774809,0.97338676,0.00012018969,0.020137526,0.00013031557],"about_ca_topic_score_codex":0.00009179499,"about_ca_topic_score_gemma":0.000010749406,"teacher_disagreement_score":0.020849543,"about_ca_system_score_codex":0.00012519295,"about_ca_system_score_gemma":0.0001775749,"threshold_uncertainty_score":0.99974334},"labels":[],"label_agreement":null},{"id":"W2799293533","doi":"10.1124/mol.117.111161","title":"Thyroid Hormones Are Transport Substrates and Transcriptional Regulators of Organic Anion Transporting Polypeptide 2B1","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Hormone; Organic anion-transporting polypeptide; Endocrinology; Internal medicine; Chemistry; Estrone sulfate; Thyroid; Thyroid hormone receptor; Levothyroxine; Transactivation; Triiodothyronine; Biology; Transporter; Gene expression; Estrone; Medicine; Biochemistry; Gene","score_opus":0.008436874645045889,"score_gpt":0.25425732708500143,"score_spread":0.24582045243995554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2799293533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930226,0.002198123,0.0027709873,0.0008488434,0.0002886913,0.00038041043,0.000029240475,0.00007946004,0.00038161117],"genre_scores_gemma":[0.9981393,0.0001964359,0.00073656806,0.00048737306,0.000163927,0.0000131278375,0.000069633315,0.000048487396,0.00014510701],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844116,0.000039736267,0.0005000755,0.00038777653,0.00026911244,0.00036215136],"domain_scores_gemma":[0.99932814,0.000012310394,0.00016273576,0.00014897692,0.00015928576,0.00018857686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021033104,0.00024517076,0.00048674032,0.00015406351,0.00009361727,0.0000036454092,0.00010002354,0.00017697929,0.00044290774],"category_scores_gemma":[0.000003243884,0.00022424058,0.00016189543,0.000268559,0.00038463637,0.00006987285,0.000004299072,0.00019826255,0.000005379931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065557,0.00017074423,0.018233133,0.00016900925,0.00018135377,0.00023398426,0.00052399235,0.0000025337322,0.9789338,0.0006180661,0.00004375107,0.00023405245],"study_design_scores_gemma":[0.00222962,0.00044898337,0.17569052,0.00006447519,0.0005213983,0.000094414,0.00020516936,0.000024235129,0.81985193,0.0001966426,0.00048733177,0.00018528425],"about_ca_topic_score_codex":0.000015386817,"about_ca_topic_score_gemma":0.00007767947,"teacher_disagreement_score":0.15908188,"about_ca_system_score_codex":0.000023198558,"about_ca_system_score_gemma":0.0000957156,"threshold_uncertainty_score":0.9144265},"labels":[],"label_agreement":null},{"id":"W2799814627","doi":"10.1124/mol.118.112144","title":"Comparison of Hepatic NRF2 and Aryl Hydrocarbon Receptor Binding in 2,3,7,8-Tetrachlorodibenzo-p-dioxin–Treated Mice Demonstrates NRF2-Independent PKM2 Induction","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Institute of General Medical Sciences; College of Engineering, Michigan State University; National Institutes of Health; Michigan State University","keywords":"Aryl hydrocarbon receptor; PKM2; Chromatin immunoprecipitation; Chemistry; Gene isoform; Molecular biology; Gene; Cell biology; Biology; Transcription factor; Gene expression; Pyruvate kinase; Biochemistry; Metabolism; Glycolysis; Promoter","score_opus":0.015238932805541408,"score_gpt":0.30805004835663735,"score_spread":0.29281111555109596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2799814627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972641,0.0011447595,0.0003222607,0.00009258992,0.00036676115,0.00039964693,0.00003729768,0.000016340373,0.0003562437],"genre_scores_gemma":[0.9986615,0.00018013535,0.00049464696,0.00014166239,0.00020644127,0.000035898684,0.00021190589,0.0000368178,0.0000309741],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981308,0.0001743645,0.0005127541,0.00062354404,0.00014269707,0.00041581853],"domain_scores_gemma":[0.99923897,0.000028822573,0.00025733592,0.0002162802,0.00012883477,0.00012977389],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023234692,0.00029074022,0.00042275214,0.000180523,0.00007220269,0.000015291702,0.00023122129,0.00032973537,0.000058756053],"category_scores_gemma":[0.000059414284,0.00031814654,0.00008067761,0.00020192267,0.00037711422,0.000010279323,0.00015790328,0.00025842813,0.000015467205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002636126,0.00025231528,0.051252652,0.00003911055,0.00013273972,0.0000075947987,0.0001584514,0.000037593734,0.94690156,0.00001006757,0.00028947953,0.00065482286],"study_design_scores_gemma":[0.0014010692,0.00053467095,0.0047951057,0.000024657184,0.000078159545,0.000016408669,0.00015905671,0.00041442257,0.9918679,0.00004804242,0.00036734395,0.00029314499],"about_ca_topic_score_codex":0.00010062368,"about_ca_topic_score_gemma":0.00008203988,"teacher_disagreement_score":0.046457548,"about_ca_system_score_codex":0.000051309864,"about_ca_system_score_gemma":0.00006284337,"threshold_uncertainty_score":0.99992704},"labels":[],"label_agreement":null},{"id":"W2808396723","doi":"10.1124/mol.118.112177","title":"Lipophilicity of the Cystic Fibrosis Drug, Ivacaftor (VX-770), and Its Destabilizing Effect on the Major CF-causing Mutation: F508del","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University; Hospital for Sick Children; University of Toronto; Simon Fraser University","funders":"Canadian Institutes of Health Research; Cystic Fibrosis Canada","keywords":"Ivacaftor; Cystic fibrosis; Chemistry; Cystic fibrosis transmembrane conductance regulator; Lipophilicity; Lipid bilayer; Liposome; Mutation; Biophysics; Pharmacology; Membrane; Biochemistry; Internal medicine; Medicine; Biology","score_opus":0.013611565251434005,"score_gpt":0.3251325528858702,"score_spread":0.31152098763443614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808396723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99356574,0.0011218733,0.00032161575,0.0031619647,0.00022762714,0.0012700903,0.000012663555,0.00003247819,0.00028596775],"genre_scores_gemma":[0.99782246,0.00001325184,0.00048280886,0.0012580268,0.00021210626,0.00009399654,0.000003412391,0.000032559317,0.000081349724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978383,0.0006812511,0.0002826473,0.00036638527,0.00043300164,0.00039838214],"domain_scores_gemma":[0.9977726,0.00147332,0.000130912,0.00032335753,0.00016659877,0.0001332186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000615969,0.00020975478,0.0003269017,0.0000981147,0.00026795195,0.000018760142,0.00020112572,0.00007285811,0.00023087564],"category_scores_gemma":[0.0013698302,0.00012518818,0.00011334229,0.00039232124,0.0005776575,0.00005421302,0.00021842864,0.0003396035,0.000027932298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069444283,0.000073625,0.00030749824,0.00020927345,0.00012163817,0.000057769004,0.00018163308,0.000026164727,0.9962982,0.00010979141,0.0006027867,0.0013171766],"study_design_scores_gemma":[0.0016539028,0.0011152776,0.0036933685,0.00016215329,0.00030645943,0.00012775282,0.000048537146,0.0033616931,0.98853314,0.00015703843,0.00072456134,0.00011609681],"about_ca_topic_score_codex":0.000023769919,"about_ca_topic_score_gemma":0.000003989359,"teacher_disagreement_score":0.007765042,"about_ca_system_score_codex":0.000098387114,"about_ca_system_score_gemma":0.0001066955,"threshold_uncertainty_score":0.5105026},"labels":[],"label_agreement":null},{"id":"W2811087712","doi":"10.1124/mol.118.112755","title":"Long-Acting β2-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)–Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Alberta Innovates; AstraZeneca","keywords":"Glucocorticoid receptor; Glucocorticoid; Transcription (linguistics); Gene; Adrenergic receptor; Transcription factor; Biology; Receptor; Chemistry; Genetics; Endocrinology; Philosophy","score_opus":0.008168914437040079,"score_gpt":0.2698563313688294,"score_spread":0.2616874169317893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2811087712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8865586,0.004454387,0.10436016,0.00033610314,0.0025900875,0.001273865,0.000027977638,0.0002188511,0.00017995058],"genre_scores_gemma":[0.99243677,0.00020458411,0.00096827536,0.004445504,0.00083704724,0.00022153907,0.00022769882,0.00013781557,0.0005207952],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971698,0.00039899585,0.00046966996,0.0008092343,0.00039422,0.00075809605],"domain_scores_gemma":[0.99871904,0.00006628635,0.00022584695,0.0003511755,0.00019671136,0.00044093002],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00018576949,0.00045472578,0.0005761619,0.00015829813,0.00020780697,0.00002956695,0.00022105472,0.0002979514,0.0029419444],"category_scores_gemma":[0.00003198304,0.00042740646,0.0002625161,0.00040060128,0.00026140056,0.00010015354,0.0000519562,0.00033480502,0.0010491401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007249567,0.00045340936,0.00016781948,0.00013614581,0.00021505945,0.00033363877,0.00015938602,0.0000052425094,0.97688955,0.0000058488913,0.0058354517,0.015073485],"study_design_scores_gemma":[0.002904861,0.001334421,0.00062422274,0.000039466217,0.0002786029,0.000051118517,0.000025202611,0.00031713542,0.9581433,0.000012719743,0.035861712,0.00040721823],"about_ca_topic_score_codex":0.000008789234,"about_ca_topic_score_gemma":0.0000019372412,"teacher_disagreement_score":0.10587812,"about_ca_system_score_codex":0.00017756187,"about_ca_system_score_gemma":0.00015549293,"threshold_uncertainty_score":0.9998178},"labels":[],"label_agreement":null},{"id":"W2829971242","doi":"10.1124/mol.118.112615","title":"An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1)","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Tel Aviv University","keywords":"Cyclic nucleotide-binding domain; ATP-binding cassette transporter; Transmembrane domain; ATP hydrolysis; Biochemistry; Allosteric regulation; Binding site; Transporter; Efflux; Nucleotide; Plasma protein binding; Biology; Biophysics; Walker motifs; Homology modeling; Amino acid; ATPase; Gene; Receptor; Enzyme","score_opus":0.01716783418880646,"score_gpt":0.30568702091981237,"score_spread":0.2885191867310059,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2829971242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9689645,0.0002351867,0.027579574,0.0008761144,0.00021129669,0.0018258329,0.000042964664,0.00007043094,0.00019407617],"genre_scores_gemma":[0.9821899,0.000007670413,0.016456818,0.0005712241,0.00037370258,0.00013429752,0.000025333145,0.00006573721,0.00017532975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980261,0.00013997043,0.0005456455,0.00048092048,0.00029714694,0.0005102527],"domain_scores_gemma":[0.99905425,0.00009124374,0.00026780265,0.00028647901,0.0001225233,0.00017767563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007163044,0.0002768848,0.0005943996,0.00015204083,0.00036467094,0.000023064187,0.0002422585,0.00015167311,0.000057395715],"category_scores_gemma":[0.000038295122,0.00022019366,0.00015737703,0.00020370225,0.00037287222,0.000098734345,0.000035089583,0.00024933528,0.0000043947707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047489753,0.00006305058,0.00070790784,0.00044474873,0.000253297,0.00006394601,0.0028241246,0.000008227419,0.9944513,0.00010006478,0.00005176843,0.0005566641],"study_design_scores_gemma":[0.0030218281,0.0003469258,0.00060792686,0.00027847302,0.00066461274,0.0000069017783,0.00043567363,0.00048377336,0.99275017,0.00043436335,0.0007405153,0.00022883907],"about_ca_topic_score_codex":0.000012275686,"about_ca_topic_score_gemma":0.000010924322,"teacher_disagreement_score":0.0132253645,"about_ca_system_score_codex":0.000048272588,"about_ca_system_score_gemma":0.000086110056,"threshold_uncertainty_score":0.89792365},"labels":[],"label_agreement":null},{"id":"W2889664495","doi":"10.1124/mol.118.112821","title":"Molecular Characterization of Binding Loop E in the Nematode Cys-Loop GABA Receptor","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Insect and Pesticide Research","field":"Agricultural and Biological Sciences","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Tech University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Agonist; Receptor; Cysteine; Mutant; Amino acid; Biochemistry; Chemistry; Biophysics; Biology; Gene","score_opus":0.023851023990416036,"score_gpt":0.3015779582659912,"score_spread":0.27772693427557515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889664495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996771,0.000051921237,0.000038399903,0.0016877651,0.00019206852,0.00032688177,0.00001978754,0.00001686869,0.0008953013],"genre_scores_gemma":[0.9985231,0.00003341369,0.000018274899,0.0010707915,0.00017072649,0.000035945093,0.00009405586,0.0000018579058,0.000051827174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854803,0.00044658693,0.00022184974,0.00021447647,0.00022604552,0.00034298564],"domain_scores_gemma":[0.9995964,0.000107628686,0.000084518,0.0000571944,0.000104615065,0.00004961821],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00047129454,0.00011471464,0.00016060824,0.000040788647,0.00009739522,0.000023325387,0.00038103206,0.00010193257,0.00175977],"category_scores_gemma":[0.00003890014,0.00004635722,0.000065296364,0.0006130408,0.00015090265,0.00005339577,0.00007400091,0.00017308496,0.0000998245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048039925,0.00008193886,0.0010356815,0.000008929457,0.000013284132,0.000042217154,0.00011596939,0.0000016738213,0.99514526,0.0002919752,0.00015445147,0.003060588],"study_design_scores_gemma":[0.00022978606,0.00031706135,0.009429284,0.000011527251,0.000015209832,0.000012785452,0.000057407844,0.00026327174,0.98640496,0.000086734995,0.0030574226,0.00011452389],"about_ca_topic_score_codex":0.000069095375,"about_ca_topic_score_gemma":0.000031005977,"teacher_disagreement_score":0.008740267,"about_ca_system_score_codex":0.000018398161,"about_ca_system_score_gemma":0.000016846845,"threshold_uncertainty_score":0.9991528},"labels":[],"label_agreement":null},{"id":"W2897971152","doi":"10.1124/mol.118.113290","title":"Involvement of 5-HT1A and 5-HT2A Receptors but Not α2-Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Ottawa","funders":"Allergan; Gedeon Richter","keywords":"Agonist; Partial agonist; Chemistry; 5-HT receptor; Receptor; Serotonin; Internal medicine; Pharmacology; Endocrinology; Medicine","score_opus":0.016815675970153526,"score_gpt":0.3029175634587346,"score_spread":0.28610188748858106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897971152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965375,0.000056526478,0.00001716091,0.0015541969,0.00038548937,0.0013791448,0.000008008599,0.000012637393,0.000049301343],"genre_scores_gemma":[0.9901355,0.000082822466,0.000043361935,0.0094155865,0.000035483095,0.0002541307,0.0000013821679,0.00001973075,0.000012018478],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99582624,0.0021649366,0.00053659943,0.00057020725,0.0003770014,0.00052498595],"domain_scores_gemma":[0.9987354,0.00070241326,0.00017286601,0.00030603725,0.000034328288,0.000048948983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005860348,0.00026905123,0.00042416365,0.0002799821,0.000050240487,0.000014858415,0.0008785825,0.00013101204,0.000118163],"category_scores_gemma":[0.00016123895,0.00017958357,0.000084084015,0.000950165,0.0008516391,0.000090627174,0.00012650626,0.0005508668,0.000007052253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027355464,0.00041625206,0.0015071345,0.000039745493,0.000007178604,0.00034657444,0.0014123002,0.000011387194,0.9949269,0.00017782536,0.00040761865,0.00047347575],"study_design_scores_gemma":[0.0019278353,0.0015564222,0.0054194382,0.000020012205,0.00003885265,0.000029153767,0.000052621956,0.000038143688,0.9902447,0.00010891171,0.00040678156,0.00015716923],"about_ca_topic_score_codex":0.00012138854,"about_ca_topic_score_gemma":0.00004190551,"teacher_disagreement_score":0.007861389,"about_ca_system_score_codex":0.000054106808,"about_ca_system_score_gemma":0.000052581676,"threshold_uncertainty_score":0.73232055},"labels":[],"label_agreement":null},{"id":"W2899979611","doi":"10.1124/mol.118.113480","title":"Identification of Peracetylated Quercetin as a Selective 12-Lipoxygenase Pathway Inhibitor in Human Platelets","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick; Université de Moncton","keywords":"Chemistry; Arachidonate 5-lipoxygenase; Lipid signaling; Lipoxygenase; Cyclooxygenase; Eicosanoid; Hydroxyeicosatetraenoic acid; Biochemistry; HEK 293 cells; Cell culture; Enzyme; Quercetin; Pharmacology; Receptor; Biology; Arachidonic acid","score_opus":0.006978334878834326,"score_gpt":0.3014936492422004,"score_spread":0.2945153143633661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899979611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99741656,0.00011062946,0.000071155955,0.00018643477,0.00048594194,0.00082291296,0.0000048100155,0.000049956052,0.00085160555],"genre_scores_gemma":[0.9986967,0.000007789086,0.000028677825,0.0006131869,0.00030715228,0.000083052226,0.0000274619,0.000034740387,0.00020124903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983427,0.00028998958,0.00048484682,0.00034090612,0.00021367024,0.00032790718],"domain_scores_gemma":[0.99922776,0.000040567917,0.00018278757,0.00019203093,0.00022425753,0.00013260238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000507522,0.00017877939,0.00036232325,0.00030196906,0.000063328866,0.0000054822476,0.00009187787,0.00019763739,0.00035036323],"category_scores_gemma":[0.000105191764,0.00017905173,0.0000836008,0.00030768308,0.00018028327,0.000048957907,0.000040924013,0.0002919889,0.00013442343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050321146,0.0003525832,0.00085074105,0.000086571636,0.00008318046,0.00066988595,0.0010147108,0.000009084298,0.9947402,0.00009293374,0.00097593426,0.00062099315],"study_design_scores_gemma":[0.0035446174,0.00097421586,0.0043563615,0.00004196447,0.00007522906,0.000079842604,0.00004219636,0.0006881853,0.9890435,0.00005857803,0.0009474585,0.00014787725],"about_ca_topic_score_codex":0.000060530085,"about_ca_topic_score_gemma":0.000023845672,"teacher_disagreement_score":0.005696696,"about_ca_system_score_codex":0.00012976554,"about_ca_system_score_gemma":0.00020706154,"threshold_uncertainty_score":0.7301518},"labels":[],"label_agreement":null},{"id":"W2906592541","doi":"10.1124/mol.118.114231","title":"S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Francis Xavier University","funders":"Natural Sciences and Engineering Research Council of Canada; Servier; Agence Nationale de la Recherche","keywords":"Reactive oxygen species; NAD+ kinase; Enzyme; Reductase; Quinone; Biochemistry; Cytosol; Chemistry; Cell biology; Biology","score_opus":0.04606515854142725,"score_gpt":0.37843262684054435,"score_spread":0.3323674682991171,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906592541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99219996,0.00053448445,0.0011713506,0.0017928719,0.002424628,0.000442822,0.000096927186,0.00011156599,0.001225385],"genre_scores_gemma":[0.991312,0.00013700052,0.00027127995,0.0064050355,0.0011625284,0.000054582237,0.00017899444,0.000044433174,0.00043413433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977667,0.0005309359,0.00035259398,0.0005991702,0.0001478179,0.0006028081],"domain_scores_gemma":[0.99913377,0.00005854234,0.00014662747,0.00017642272,0.00012803556,0.00035663],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003899246,0.0003188397,0.00031632325,0.00016356747,0.000303065,0.00003205239,0.00024184992,0.0003861705,0.0022979046],"category_scores_gemma":[0.00002823638,0.00033212022,0.00008864979,0.00027236965,0.0008994796,0.00011125492,0.00017762276,0.0005385033,0.00023398746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003617062,0.0003483583,0.00053376256,0.000033585064,0.00017326685,0.00033671528,0.0002396889,6.188055e-7,0.98302746,0.00032245094,0.012584666,0.0020377196],"study_design_scores_gemma":[0.0018874555,0.00025051573,0.00046397786,0.000007668649,0.0001881918,0.000100716425,0.000028672719,0.0006151003,0.88448787,0.000116169394,0.11153745,0.00031622715],"about_ca_topic_score_codex":0.000005779587,"about_ca_topic_score_gemma":8.0293614e-7,"teacher_disagreement_score":0.098952785,"about_ca_system_score_codex":0.00007044206,"about_ca_system_score_gemma":0.00006847706,"threshold_uncertainty_score":0.9999131},"labels":[],"label_agreement":null},{"id":"W2910953004","doi":"10.1124/mol.118.114751","title":"Blockade of the Human Ether A-Go-Go–Related Gene (hERG) Potassium Channel by Fentanyl","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"hERG; Fentanyl; Potassium channel blocker; Potassium channel; Repolarization; Depolarization; Pharmacology; Sudden death; Cardiac action potential; Ventricular action potential; (+)-Naloxone; Patch clamp; Chemistry; Medicine; Internal medicine; Anesthesia; Electrophysiology; Antagonist","score_opus":0.005127051785867316,"score_gpt":0.26268506561387883,"score_spread":0.2575580138280115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910953004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99071896,0.0013787235,0.000021657974,0.0027787348,0.0008704575,0.0006336749,0.0000148744,0.000042854983,0.0035400877],"genre_scores_gemma":[0.9908327,0.00003497822,0.000021360422,0.0037549923,0.00013246812,0.000031619493,0.00003802308,0.00004323746,0.005110621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852574,0.00027433835,0.000283627,0.0003412771,0.00017191986,0.00040307632],"domain_scores_gemma":[0.99931353,0.000031742333,0.00014606597,0.0003535565,0.00006549292,0.00008958076],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013838598,0.0002040074,0.0004406117,0.00006506057,0.00007469818,0.0000025848285,0.0001712757,0.00026207708,0.0011575322],"category_scores_gemma":[0.000007578247,0.0001559684,0.00030226988,0.00022540736,0.0001975077,0.000019146808,0.00011190114,0.00052978034,0.00020630493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000121596415,0.00015501738,0.0003963805,0.000028876717,0.00062259886,0.00019477298,0.00009298795,0.00015335901,0.988937,0.00012600685,0.00909451,0.00007690048],"study_design_scores_gemma":[0.0030500398,0.00033465822,0.00214019,0.000013905171,0.00047693308,0.00031270238,0.000011849219,0.00014623019,0.9886886,0.0002690341,0.004396876,0.00015898045],"about_ca_topic_score_codex":0.000014295429,"about_ca_topic_score_gemma":4.4633236e-7,"teacher_disagreement_score":0.004697635,"about_ca_system_score_codex":0.00005545172,"about_ca_system_score_gemma":0.000070867965,"threshold_uncertainty_score":0.99975556},"labels":[],"label_agreement":null},{"id":"W2923061882","doi":"10.1124/mol.118.114389","title":"Characterization of 6-Mercaptopurine Transport by the SLC43A3-Encoded Nucleobase Transporter","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; University of Alberta; Cancer Research Society","keywords":"HEK 293 cells; Nucleobase; Chemistry; Transporter; Transfection; Extracellular; Membrane transport protein; Efflux; Biochemistry; Gene; DNA","score_opus":0.003676902508598354,"score_gpt":0.22448291659102437,"score_spread":0.220806014082426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2923061882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99279934,0.00071249966,0.004648556,0.0005259516,0.00025478617,0.00036678414,0.000061057595,0.000013192183,0.0006178291],"genre_scores_gemma":[0.99620336,0.00011218599,0.00005066841,0.001849523,0.000103201215,0.000028744875,0.0006283861,0.00003276554,0.0009911899],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895054,0.0000861145,0.00028950078,0.00030607797,0.000132644,0.00023513222],"domain_scores_gemma":[0.999497,0.000007366214,0.00011933539,0.00025196015,0.00006654906,0.00005781854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013883504,0.00017173805,0.00019531297,0.000034355613,0.000036490845,0.0000037739248,0.00025825636,0.0001278999,0.0006567729],"category_scores_gemma":[0.0000023438286,0.000140332,0.00013234865,0.00010941067,0.000081314705,0.0000053713015,0.000025220248,0.000115298295,0.00001800173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015862177,0.00009817855,0.0016775852,0.00002635643,0.00010986772,0.000012314099,0.000057395595,0.00012135313,0.9942012,0.00004111145,0.0033574756,0.00013853976],"study_design_scores_gemma":[0.0010574883,0.00019390111,0.0010081645,0.0000048810225,0.00008371252,0.000017924664,0.0000138484,0.00008519835,0.95174325,0.0000074291233,0.045624897,0.00015931964],"about_ca_topic_score_codex":0.000015527245,"about_ca_topic_score_gemma":6.231833e-7,"teacher_disagreement_score":0.042457964,"about_ca_system_score_codex":0.0000059725735,"about_ca_system_score_gemma":0.00004329841,"threshold_uncertainty_score":0.71912026},"labels":[],"label_agreement":null},{"id":"W2937231654","doi":"10.1124/mol.118.115196","title":"Functional CRISPR and shRNA Screens Identify Involvement of Mitochondrial Electron Transport in the Activation of Evofosfamide","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Health Research Council of New Zealand; Cancer Research Trust New Zealand; Royal Society; Cancer Society of New Zealand; American Society for Pharmacology and Experimental Therapeutics","keywords":"Mitochondrion; Biology; Molecular biology; Small hairpin RNA; Respiratory chain; DNA; Biochemistry; Chemistry; RNA; Gene","score_opus":0.009755151477266057,"score_gpt":0.275935793624264,"score_spread":0.26618064214699794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937231654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953908,0.0012648995,0.0018063631,0.00019752939,0.0006745023,0.0004402117,0.000012767624,0.0000025532092,0.00021041284],"genre_scores_gemma":[0.9983779,0.0003317666,0.000115258146,0.0006519201,0.00030052193,0.00003871796,0.00009585372,0.000011940349,0.00007612267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990154,0.00012166526,0.00025808022,0.0002520621,0.000170283,0.00018250538],"domain_scores_gemma":[0.99960005,0.000015116276,0.00011761399,0.00016456067,0.00007418212,0.000028469305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002021918,0.00011552355,0.00018597757,0.000079433914,0.000018659919,0.0000029305368,0.00013513814,0.00010996152,0.000058545636],"category_scores_gemma":[0.000010375152,0.000102774924,0.000086061795,0.00011027999,0.000078081386,0.000006053619,0.00003262078,0.00011535522,0.0000012893843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044233748,0.000103836835,0.0022834854,0.000037841535,0.00008233414,9.41146e-7,0.00008481641,0.00024797706,0.9948871,0.00017243852,0.0013510438,0.000305819],"study_design_scores_gemma":[0.0021159183,0.00021134176,0.032811996,0.000006698271,0.000073076364,0.000005459808,0.00006615305,0.000024261528,0.95043075,0.00007514426,0.014083121,0.00009610412],"about_ca_topic_score_codex":0.00010105333,"about_ca_topic_score_gemma":0.000037781247,"teacher_disagreement_score":0.044456404,"about_ca_system_score_codex":0.00001104026,"about_ca_system_score_gemma":0.000090548696,"threshold_uncertainty_score":0.41910398},"labels":[],"label_agreement":null},{"id":"W2941168304","doi":"10.1124/mol.118.115188","title":"Differential Regulation of Human Ether-à-Go-Go–Related Gene (hERG) Current and Expression by Activation of Protein Kinase C","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"hERG; Protein kinase C; Potassium channel; Chemistry; Pharmacology; HEK 293 cells; Long QT syndrome; Phorbol; Ubiquitin ligase; Cell biology; Phosphorylation; Biochemistry; Biology; Ubiquitin; Endocrinology; Gene; Internal medicine; QT interval; Medicine","score_opus":0.006718677374942423,"score_gpt":0.2844812703786385,"score_spread":0.2777625930036961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2941168304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979008,0.0005795283,0.00038453046,0.00012526585,0.0001419507,0.00073249184,0.000005403909,0.000017614359,0.000112456044],"genre_scores_gemma":[0.9994937,0.000025101945,0.00006189284,0.000041936903,0.00004380114,0.000030591425,0.00012804168,0.000017007127,0.00015788876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990499,0.00019384352,0.00025579767,0.00022963826,0.00012224211,0.00014856644],"domain_scores_gemma":[0.99952614,0.000019690568,0.00019378153,0.00013916094,0.00007269886,0.000048549507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064725195,0.00012181352,0.00032046947,0.000087314744,0.000029061834,0.0000013661885,0.000036428286,0.00014900646,0.00041036966],"category_scores_gemma":[0.00000780481,0.00011132574,0.00008384055,0.0000926541,0.0000918689,0.000034376288,0.000042482698,0.00021080713,0.000005297603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005052131,0.0001896864,0.00020828094,0.00013238244,0.000117334836,0.0000078241865,0.000078012265,0.00003835664,0.99637944,0.00014615378,0.00022722752,0.0019701123],"study_design_scores_gemma":[0.0028114857,0.00053194206,0.004233765,0.00007017752,0.0001359265,0.000011009438,0.0000035815588,0.00027551074,0.99140084,0.00029511552,0.00014371486,0.00008690753],"about_ca_topic_score_codex":0.0000051948177,"about_ca_topic_score_gemma":5.5857328e-8,"teacher_disagreement_score":0.0049785515,"about_ca_system_score_codex":0.00002494586,"about_ca_system_score_gemma":0.000028706832,"threshold_uncertainty_score":0.4539732},"labels":[],"label_agreement":null},{"id":"W2943560448","doi":"10.1124/mol.118.115634","title":"Preferred Formation of Heteromeric Channels between Coexpressed SK1 and IKCa Channel Subunits Provides a Unique Pharmacological Profile of Ca2+-Activated Potassium Channels","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Cystic Fibrosis Trust; British Heart Foundation","keywords":"Homomeric; Calcium-activated potassium channel; Potassium channel; SK channel; Biophysics; Chemistry; Heterologous expression; Protein subunit; Patch clamp; Apamin; N-type calcium channel; Ion channel; Biology; Cell biology; Biochemistry; Calcium channel; Calcium; Recombinant DNA; Gene; T-type calcium channel; Receptor","score_opus":0.022333820898521338,"score_gpt":0.2782707724125723,"score_spread":0.255936951514051,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943560448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921501,0.00027823448,0.004836063,0.00020449607,0.00084996055,0.0013857954,0.00007831788,0.000034611574,0.00018238871],"genre_scores_gemma":[0.9982435,0.00010292036,0.00012963999,0.00023456292,0.00021951832,0.00016427814,0.0006098473,0.000037752547,0.00025795787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981168,0.00036650163,0.0005097327,0.00044735853,0.0002002549,0.00035937974],"domain_scores_gemma":[0.9988982,0.000046079887,0.00042114142,0.00018872744,0.00031277447,0.00013304832],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002606434,0.00028459146,0.0004537517,0.00020921441,0.000056733956,0.000012814784,0.0001929905,0.00033566385,0.000111716996],"category_scores_gemma":[0.000046841702,0.00027363357,0.000115796116,0.00027328928,0.00015706886,0.00003227555,0.00017434465,0.00017018714,0.0000059433314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005807016,0.00015926494,0.00022684052,0.00021631259,0.00018080969,0.0000033133124,0.00017836476,0.0015914694,0.99583906,0.000018314504,0.00061121554,0.00039434776],"study_design_scores_gemma":[0.0025000188,0.0011454641,0.0005140502,0.000023083838,0.000099804194,0.000017021726,0.000075217926,0.0067676157,0.98706955,0.00004498752,0.0014840253,0.0002591921],"about_ca_topic_score_codex":0.00001344805,"about_ca_topic_score_gemma":3.265889e-7,"teacher_disagreement_score":0.008769527,"about_ca_system_score_codex":0.000027083204,"about_ca_system_score_gemma":0.00007301192,"threshold_uncertainty_score":0.99997157},"labels":[],"label_agreement":null},{"id":"W2943628495","doi":"10.1124/mol.118.115311","title":"Impact of Phosphodiesterase 4 Inhibition on the Operational Efficacy, Response Maxima, and Kinetics of Indacaterol-Induced Gene Expression Changes in BEAS-2B Airway Epithelial Cells: A Global Transcriptomic Analysis","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Alberta Innovates; Gilead Sciences","keywords":"Indacaterol; Transcriptome; Phosphodiesterase; Gene expression; Kinetics; Maxima; Chemistry; Pharmacology; Cell biology; Gene; Molecular biology; Biology; Immunology; Biochemistry; Enzyme; Asthma; Physics","score_opus":0.009178042996319103,"score_gpt":0.27430298731758307,"score_spread":0.265124944321264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943628495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99820435,0.00014757762,0.00055123214,0.0003202847,0.0001640915,0.0004441468,0.00014613484,0.0000047225453,0.00001747668],"genre_scores_gemma":[0.9992401,0.00005880122,0.000083725645,0.00038497712,0.000029494755,0.000027964199,0.00014261546,0.000012602477,0.000019722609],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986108,0.00043061792,0.00029399077,0.00032923554,0.00015325994,0.00018210821],"domain_scores_gemma":[0.9994443,0.000042519107,0.00015552991,0.00021242308,0.00008873781,0.00005646912],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000263541,0.00018722852,0.00026984574,0.00013983487,0.000026624906,0.00000966622,0.00009869344,0.00017262541,0.00009731239],"category_scores_gemma":[0.000020524883,0.00014162897,0.0001573049,0.00026044756,0.00009418097,0.0000061541864,0.00005850501,0.000094329174,0.0000022791273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004590485,0.00028954417,0.003413931,0.000012553193,0.0002453237,0.0000054026427,0.000120324374,0.004330147,0.9867365,0.0000075967855,0.000070819035,0.0001773966],"study_design_scores_gemma":[0.0023348648,0.0013312598,0.055678673,0.000012345219,0.000121022116,0.0000053359363,0.000019074889,0.0004905338,0.939811,0.000006640232,0.00006465896,0.00012457758],"about_ca_topic_score_codex":0.000036640664,"about_ca_topic_score_gemma":0.000030507137,"teacher_disagreement_score":0.05226474,"about_ca_system_score_codex":0.000050573533,"about_ca_system_score_gemma":0.00005799587,"threshold_uncertainty_score":0.5775462},"labels":[],"label_agreement":null},{"id":"W2949806249","doi":"10.1124/mol.118.115642","title":"The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"hERG; Ivabradine; Biophysics; Chemistry; Torsades de pointes; Repolarization; QT interval; Dofetilide; Cardiac action potential; Pharmacology; Potassium channel; Cardiology; Electrophysiology; Internal medicine; Heart rate; Biology; Medicine","score_opus":0.004828075497576577,"score_gpt":0.2972987167642212,"score_spread":0.2924706412666446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949806249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919774,0.0027801644,0.000062107814,0.0031851446,0.0005549044,0.000853097,0.0000227024,0.000017230634,0.0005472626],"genre_scores_gemma":[0.9973363,0.000119767734,0.00003023242,0.0019163479,0.00016165322,0.00006303049,0.000018478644,0.000029752162,0.00032443143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847156,0.0002529618,0.0003871326,0.00030481713,0.0001839092,0.000399644],"domain_scores_gemma":[0.9990246,0.00011164548,0.00019877843,0.00046701232,0.000098305776,0.00009961957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027526115,0.00019897545,0.0005239824,0.000070508344,0.00007504958,0.0000066011303,0.0004296746,0.00012525148,0.00018048738],"category_scores_gemma":[0.000036002522,0.00012372434,0.00020591836,0.0002673346,0.00024203307,0.000037755915,0.00025751436,0.00030892773,0.000034735687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095766044,0.00008715076,0.0007634189,0.00004099251,0.00023488616,0.000099790486,0.00017965802,0.00006503492,0.98537153,0.000064792985,0.0056630415,0.006472027],"study_design_scores_gemma":[0.0013111338,0.00084815477,0.0018863112,0.00002248412,0.00014921294,0.0002586137,0.000079365585,0.00012741206,0.9709606,0.00017824485,0.024059646,0.00011878552],"about_ca_topic_score_codex":0.000022461185,"about_ca_topic_score_gemma":0.000005209553,"teacher_disagreement_score":0.018396603,"about_ca_system_score_codex":0.00003626863,"about_ca_system_score_gemma":0.000083097206,"threshold_uncertainty_score":0.50453323},"labels":[],"label_agreement":null},{"id":"W2969357821","doi":"10.1124/mol.119.117143","title":"ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health; Canadian Institutes of Health Research; Hospital for Sick Children; Cystic Fibrosis Canada","keywords":"Arginase; Cystic fibrosis; Mucociliary clearance; Cystic fibrosis transmembrane conductance regulator; Nitric oxide; Arginine; Fibrosis; Respiratory system; Chemistry; Medicine; Internal medicine; Biochemistry; Lung","score_opus":0.009759868050807087,"score_gpt":0.2816823248102688,"score_spread":0.2719224567594617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969357821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98825747,0.006189379,0.001368175,0.0012527118,0.00009395189,0.0024908339,0.00026875385,0.000040443134,0.000038260572],"genre_scores_gemma":[0.99573,0.000215455,0.0019996765,0.0014003159,0.00004540717,0.00033163806,0.00011365039,0.000056558052,0.00010733516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99667454,0.00048591604,0.0009044144,0.00071677996,0.00064227066,0.0005761016],"domain_scores_gemma":[0.9982888,0.00039235517,0.0002733821,0.00040746166,0.00039545624,0.00024255013],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00077153987,0.00034792148,0.0008638271,0.0003859946,0.00006765341,0.000012417389,0.00022337963,0.00020236576,0.00018204386],"category_scores_gemma":[0.00045761958,0.0002938598,0.000126139,0.0012835221,0.00035812808,0.00016485788,0.00008731428,0.00048121886,0.000017140233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039133527,0.00034904337,0.00017321455,0.0016952112,0.00009588812,0.00004240735,0.00045238907,0.0013455744,0.9900166,0.00000726158,0.001474413,0.00043465765],"study_design_scores_gemma":[0.0050257733,0.0011682531,0.010798271,0.0007867523,0.00013965719,0.000019053261,0.000120305565,0.0007404253,0.9799893,0.000052450803,0.0009026008,0.00025715935],"about_ca_topic_score_codex":0.000046075307,"about_ca_topic_score_gemma":0.0000063542357,"teacher_disagreement_score":0.010625057,"about_ca_system_score_codex":0.00014938778,"about_ca_system_score_gemma":0.00021373897,"threshold_uncertainty_score":0.99995136},"labels":[],"label_agreement":null},{"id":"W2972861243","doi":"10.1124/mol.119.116483","title":"Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Antagonist; Cannabinoid; Chemistry; Cannabinoid receptor; Receptor; Stereochemistry; Biophysics; Biochemistry; Biology","score_opus":0.009977861646587132,"score_gpt":0.28217450250472453,"score_spread":0.2721966408581374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972861243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96017444,0.00034379633,0.000058416117,0.034218743,0.00068995345,0.0017547236,0.000035628425,0.00009061248,0.0026336804],"genre_scores_gemma":[0.9741255,0.000046106496,0.00022776902,0.0056487117,0.00022864966,0.00024024968,0.000092810915,0.00007776663,0.01931242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975564,0.0002634543,0.0002724922,0.0005719845,0.0005193134,0.0008163822],"domain_scores_gemma":[0.9988674,0.000023295386,0.00012060794,0.00046639398,0.00024009605,0.00028221958],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005278535,0.0002908457,0.00043678968,0.00021205252,0.00027552707,0.00006194902,0.00034152358,0.0001467633,0.003561195],"category_scores_gemma":[0.000031665164,0.00019643715,0.00014576683,0.0006663797,0.00027444283,0.00008451387,0.00020234895,0.00079360435,0.00064124615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00083326164,0.00020383106,0.0019208057,0.00016378296,0.00024364966,0.0003158528,0.00020625631,0.00007097857,0.83264166,0.00022120155,0.16253561,0.000643109],"study_design_scores_gemma":[0.0058519416,0.0014398197,0.0019480314,0.00006314063,0.00028728068,0.00034412206,0.00039996853,0.00018063727,0.63065994,0.000017763892,0.35841206,0.00039529477],"about_ca_topic_score_codex":0.00030923128,"about_ca_topic_score_gemma":0.00001768803,"teacher_disagreement_score":0.20198172,"about_ca_system_score_codex":0.00030357664,"about_ca_system_score_gemma":0.00073188817,"threshold_uncertainty_score":0.9973497},"labels":[],"label_agreement":null},{"id":"W2985115299","doi":"10.1124/mol.119.117952","title":"The I Ion Channel Activator Mefenamic Acid Requires KCNE1 and Modulates Channel Gating in a Subunit-Dependent Manner","year":2019,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Mefenamic acid; Chemistry; Repolarization; Biophysics; Conductance; Gating; Activator (genetics); Ion channel; Patch clamp; Cardiac action potential; Potassium channel; Pharmacology; Electrophysiology; Biochemistry; Biology; Receptor; Internal medicine; Physics; Chromatography; Medicine","score_opus":0.006777670082218751,"score_gpt":0.2640308025323236,"score_spread":0.25725313245010484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2985115299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935238,0.0020809427,0.000044112192,0.0027792158,0.00055772165,0.0006769486,0.0000029790222,0.000043220534,0.00029106464],"genre_scores_gemma":[0.99738264,0.00039181617,0.000018379584,0.0015753765,0.00019834029,0.00009808823,0.000014918364,0.000034586912,0.0002858492],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847317,0.00024349992,0.0002350718,0.00039721932,0.0001397643,0.0005112752],"domain_scores_gemma":[0.9994336,0.000112254456,0.00008991198,0.00022331213,0.000046015768,0.00009493964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002968884,0.00020848752,0.00035525742,0.00012354556,0.00012713889,0.000012819707,0.00009581183,0.00016773814,0.000041831187],"category_scores_gemma":[0.00003862045,0.00015836372,0.00009510245,0.00016242692,0.00012449565,0.00006793309,0.00012978572,0.00048962445,0.00004023698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005932583,0.00005272469,0.00016379986,0.000042009953,0.00019267686,0.0005002728,0.0002730229,0.00065537705,0.99601895,0.00014670582,0.0001005017,0.0012607069],"study_design_scores_gemma":[0.0041340734,0.00061001314,0.0042081773,0.000057241312,0.00016853467,0.00064734,0.00027481068,0.010829574,0.9769605,0.001430887,0.00038089152,0.00029800067],"about_ca_topic_score_codex":0.00003346887,"about_ca_topic_score_gemma":0.000005281623,"teacher_disagreement_score":0.019058486,"about_ca_system_score_codex":0.00007466073,"about_ca_system_score_gemma":0.000054861044,"threshold_uncertainty_score":0.64578855},"labels":[],"label_agreement":null},{"id":"W3014663619","doi":"10.1124/mol.119.118232","title":"Proteinase-Activated Receptor 4 Activation Triggers Cell Membrane Blebbing through RhoA and β-Arrestin","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Government of Ontario","keywords":"Cell biology; RHOA; Signal transduction; Biology; Thrombin; Arrestin; G protein-coupled receptor; Cell surface receptor; Protease-activated receptor; Receptor; Cell signaling; Cell; Biochemistry; Platelet; Immunology","score_opus":0.0312555209616305,"score_gpt":0.2901110632717506,"score_spread":0.25885554231012015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014663619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9755078,0.0001264812,0.0066264085,0.014401689,0.00019679792,0.0011354142,0.0000034489483,0.0001928142,0.0018091701],"genre_scores_gemma":[0.98406535,0.000043442982,0.0037192523,0.011807471,0.00012666456,0.000077905774,0.000044730506,0.000042551783,0.00007264937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875236,0.00015962815,0.00024157407,0.00039426642,0.0001940647,0.00025812845],"domain_scores_gemma":[0.9994383,0.00004091511,0.000121530036,0.000108333625,0.00007648385,0.00021445613],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000100555924,0.0001940543,0.0003314399,0.00006012153,0.00008681264,0.000015455405,0.00006740084,0.00014293894,0.00092708116],"category_scores_gemma":[0.00005847795,0.00019304005,0.00006440853,0.00033415135,0.000057366215,0.00010817232,0.000051009327,0.00028918716,0.00005230436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039628925,0.00013855884,0.000025127561,0.00014096744,0.00010273201,0.000034622783,0.0004235702,0.000042894302,0.99656284,0.00021251137,0.0009650631,0.0009548439],"study_design_scores_gemma":[0.0043733944,0.00044683702,0.000062307685,0.000025618358,0.0001871878,0.0000088837,0.0000891483,0.0010042643,0.9836391,0.000058324295,0.009931608,0.0001732909],"about_ca_topic_score_codex":0.000014539805,"about_ca_topic_score_gemma":1.08246546e-7,"teacher_disagreement_score":0.012923684,"about_ca_system_score_codex":0.000039387112,"about_ca_system_score_gemma":0.000082435676,"threshold_uncertainty_score":0.99998623},"labels":[],"label_agreement":null},{"id":"W3019066803","doi":"10.1124/mol.119.119271","title":"Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Hypokalemia; Hypoxia (environmental); hERG; Anesthesia; Fentanyl; Alkalosis; Medicine; Pharmacology; Chemistry; Potassium channel; Cardiology; Internal medicine; Acidosis; Oxygen","score_opus":0.010296979526037392,"score_gpt":0.26114019226282564,"score_spread":0.2508432127367882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019066803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815349,0.0046621747,0.00004052955,0.012635164,0.00018166186,0.0006111774,0.000020734271,0.00002413106,0.00028950628],"genre_scores_gemma":[0.99068165,0.0005371832,0.000038477287,0.0084305685,0.0001296178,0.000043009906,0.000010348985,0.000022972989,0.00010618669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857664,0.00030888457,0.00032945749,0.000334422,0.00017037411,0.00028024905],"domain_scores_gemma":[0.9992411,0.00015522257,0.00016963691,0.0001904852,0.000104193095,0.0001393669],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014293019,0.00018404065,0.0006267492,0.000039383234,0.000045701883,0.000002723493,0.00013279043,0.00015054978,0.00014935547],"category_scores_gemma":[0.00007002144,0.00014230776,0.00017620376,0.0002627004,0.00041665765,0.00002538326,0.00011848443,0.0003213827,0.0000074426466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015106085,0.00007835421,0.000051008126,0.00009617563,0.00054852164,0.00024441179,0.00052538083,0.000031540996,0.98223776,0.000057219073,0.014202798,0.0004162325],"study_design_scores_gemma":[0.005446486,0.00062550977,0.00012855223,0.000017368766,0.00046059745,0.00018608452,0.000052893618,0.00089665223,0.99047846,0.00007100199,0.001520104,0.000116310504],"about_ca_topic_score_codex":0.000041167434,"about_ca_topic_score_gemma":2.5042968e-7,"teacher_disagreement_score":0.012682693,"about_ca_system_score_codex":0.000013860871,"about_ca_system_score_gemma":0.0000688315,"threshold_uncertainty_score":0.5803142},"labels":[],"label_agreement":null},{"id":"W3021817436","doi":"10.1124/mol.119.118950","title":"Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFRα1","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"H. Lundbeck A/S; Sigrid Juséliuksen Säätiö; Lundbeckfonden; McGill University","keywords":"Glial cell line-derived neurotrophic factor; GDNF family of ligands; Proto-Oncogene Proteins c-ret; Neurotrophic factors; Cell biology; Receptor tyrosine kinase; Biology; Ectodomain; Receptor; Signal transduction; Tyrosine kinase; Chemistry; Biochemistry","score_opus":0.018654319233720754,"score_gpt":0.24039849949893813,"score_spread":0.22174418026521736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3021817436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99196464,0.00081857,0.0027218198,0.0028473362,0.0002631585,0.0007965719,0.000067501365,0.000030010773,0.0004904081],"genre_scores_gemma":[0.9943887,0.00028274953,0.00009968075,0.004517056,0.000087973924,0.00010237858,0.00024340034,0.00006110505,0.00021694887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980132,0.0002941627,0.00034786537,0.00064109475,0.0002694106,0.0004342942],"domain_scores_gemma":[0.99911505,0.00002853466,0.00026752273,0.00024288779,0.00015264799,0.00019337174],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020070998,0.0003413141,0.00032277431,0.000050758103,0.00011473358,0.000025079427,0.00055827794,0.00025964846,0.00027926493],"category_scores_gemma":[0.000094523144,0.0002848167,0.00018347935,0.00026851526,0.00022476571,0.000006868376,0.00031502766,0.00031975226,0.000028337476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008457822,0.00009689333,0.00037366996,0.000028486682,0.0003161887,0.000018788078,0.00015088815,0.00017088183,0.9832886,0.0000059750005,0.014207523,0.000496346],"study_design_scores_gemma":[0.0014674912,0.00067255966,0.00023933158,0.00000744733,0.000071319824,0.000007311093,0.000117866744,0.00022564006,0.9855037,0.000016685024,0.011355199,0.00031547586],"about_ca_topic_score_codex":0.000026837572,"about_ca_topic_score_gemma":0.0000015234626,"teacher_disagreement_score":0.0028523246,"about_ca_system_score_codex":0.000019341715,"about_ca_system_score_gemma":0.00013000621,"threshold_uncertainty_score":0.9999604},"labels":[],"label_agreement":null},{"id":"W3022322095","doi":"10.1124/mol.120.119909","title":"Inhibition of Brain Epidermal Growth Factor Receptor Activation: A Novel Target in Neurodegenerative Diseases and Brain Injuries","year":2020,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Neuroprotection; Medicine; Neurodegeneration; Epidermal growth factor receptor; EGFR inhibitors; Neuroscience; Amyotrophic lateral sclerosis; Disease; Multiple sclerosis; Receptor; Pathology; Pharmacology; Internal medicine; Immunology; Biology","score_opus":0.022441301718759566,"score_gpt":0.3398319508523709,"score_spread":0.3173906491336113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022322095","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.05525919,0.937388,0.0014123,0.002295809,0.0002983508,0.0018432357,0.0014123953,0.000026981299,0.000063759246],"genre_scores_gemma":[0.023103597,0.9680865,0.0008684763,0.0025567885,0.0008827061,0.00080066064,0.0032719932,0.00024385932,0.00018545662],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.996578,0.0010751871,0.00073467486,0.0009299431,0.0002578724,0.00042435172],"domain_scores_gemma":[0.99881357,0.00019589157,0.0003754966,0.00023603364,0.00015267763,0.00022630848],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018214755,0.000527937,0.0012207864,0.00032896403,0.00006666843,0.000021579099,0.0002444359,0.0004753217,0.00008432201],"category_scores_gemma":[0.00078395096,0.00054155226,0.00030392717,0.00044857585,0.00036838098,0.0000146305865,0.00041073567,0.000537356,0.0000089252935],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014004036,0.00022320592,0.000012187615,0.0029844476,0.0002259964,0.00005250509,0.00009943741,0.000005945085,0.9679119,0.000058948444,0.012028761,0.016256627],"study_design_scores_gemma":[0.0008303141,0.00034561058,0.0000097514,0.0003388888,0.00007953802,0.00001446561,0.000008558435,0.0000127644,0.47396436,0.000009104221,0.5240086,0.0003780813],"about_ca_topic_score_codex":0.000018268347,"about_ca_topic_score_gemma":0.0000032172682,"teacher_disagreement_score":0.5119798,"about_ca_system_score_codex":0.00009759761,"about_ca_system_score_gemma":0.0006415499,"threshold_uncertainty_score":0.9997036},"labels":[],"label_agreement":null},{"id":"W3037293035","doi":"10.1124/mol.120.119644","title":"Heteromeric Assembly of Truncated Neuronal Kv7 Channels: Implications for Neurologic Disease and Pharmacotherapy","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Pharmacotherapy; Neuroscience; Disease; Medicine; Biology; Pathology; Internal medicine","score_opus":0.02846808972468022,"score_gpt":0.3030575238656273,"score_spread":0.27458943414094705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037293035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9562359,0.0006008938,0.032667972,0.009297764,0.00048236956,0.0005821401,0.000074521224,0.000029054921,0.00002942267],"genre_scores_gemma":[0.9882316,0.0001594734,0.00014066687,0.010634804,0.00037640255,0.0001575556,0.00023739277,0.00002864528,0.000033449294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990553,0.00010532749,0.00020315421,0.00038363243,0.000057677375,0.00019486604],"domain_scores_gemma":[0.9994726,0.000022427768,0.00010678331,0.000101672515,0.000101857746,0.00019463898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006194775,0.00015041107,0.0001542287,0.000046691577,0.000063748405,0.0000089602145,0.00012119404,0.000075705546,0.00003070814],"category_scores_gemma":[0.000047001813,0.00015463983,0.00010150074,0.00012289884,0.00008661465,0.0000050920694,0.000053578,0.000063241096,0.0000017869583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071867555,0.0000716157,0.00030878314,0.00003584599,0.00007090607,0.000001751254,0.000019966355,0.001700856,0.99339604,0.00009250542,0.002450399,0.0011326516],"study_design_scores_gemma":[0.0030552798,0.0012206576,0.0048565115,0.0000012496779,0.00014498926,0.00001001401,0.0000070399933,0.016418898,0.9318562,0.00012958054,0.042046674,0.00025290073],"about_ca_topic_score_codex":7.531096e-7,"about_ca_topic_score_gemma":6.558713e-8,"teacher_disagreement_score":0.06153984,"about_ca_system_score_codex":0.000004253035,"about_ca_system_score_gemma":0.00004238857,"threshold_uncertainty_score":0.6306029},"labels":[],"label_agreement":null},{"id":"W3043440868","doi":"10.1124/molpharm.120.000089","title":"Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior","year":2020,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; University of Ottawa","funders":"Canadian Institutes of Health Research; Alberta Innovates; Canada Research Chairs","keywords":"Metabotropic glutamate receptor 5; Metabotropic glutamate receptor; Neuroscience; Glutamatergic; Metabotropic glutamate receptor 1; Neurotransmission; Glutamate receptor; Synaptic plasticity; Metabotropic glutamate receptor 7; Metabotropic glutamate receptor 8; Biology; Receptor","score_opus":0.06327072102837875,"score_gpt":0.38372509800146115,"score_spread":0.32045437697308243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043440868","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.046365257,0.9439039,0.00015867234,0.0015348975,0.002324579,0.0045701116,0.00057083945,0.00045105047,0.00012069642],"genre_scores_gemma":[0.009618376,0.9826873,0.00007833059,0.005567899,0.0003124665,0.0014053733,0.00003260647,0.00022016081,0.0000774665],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99313384,0.0020621947,0.0009544677,0.0021782776,0.0005021732,0.0011690231],"domain_scores_gemma":[0.9979847,0.0005156626,0.00045843355,0.00041901198,0.00005173463,0.0005704513],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032766885,0.0009145152,0.0018064425,0.0004993803,0.0005538878,0.00013545188,0.0012108771,0.00035296235,0.0004482915],"category_scores_gemma":[0.00015477782,0.0008099143,0.00054007675,0.0011355033,0.00055822806,0.00017110897,0.00034367217,0.0018869669,0.00043721503],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003665953,0.00023746147,0.0000021463147,0.00088215334,0.00005311744,0.0026331518,0.000022253515,0.000015381293,0.8943578,0.00014201303,0.0003983984,0.10121944],"study_design_scores_gemma":[0.00069049763,0.00038056745,0.0000035891185,0.0001923935,0.0018429727,0.00028208827,0.0000016575169,0.00008462805,0.21513952,0.000014973528,0.7806523,0.0007148113],"about_ca_topic_score_codex":0.000002090702,"about_ca_topic_score_gemma":5.6131263e-8,"teacher_disagreement_score":0.7802539,"about_ca_system_score_codex":0.00009557205,"about_ca_system_score_gemma":0.0002796962,"threshold_uncertainty_score":0.9994352},"labels":[],"label_agreement":null},{"id":"W3045892068","doi":"10.1124/mol.120.119438","title":"Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease","year":2020,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse; National Institutes of Health","keywords":"Nociceptin receptor; Dysphoria; Opioid; Chronic pain; Migraine; Disease; Medicine; Addiction; κ-opioid receptor; Neuroscience; Bioinformatics; δ-opioid receptor; Microbiome; Psychiatry; Psychology; Opioid peptide; Receptor; Biology; Internal medicine","score_opus":0.03288752423899454,"score_gpt":0.3008948475960856,"score_spread":0.26800732335709104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045892068","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007113374,0.9938423,0.0014382721,0.0012398073,0.0006483562,0.002567718,0.00013247629,0.000044401688,0.000015549496],"genre_scores_gemma":[0.00038693167,0.98963416,0.00006592029,0.0088737095,0.0003436156,0.000310228,0.000031529136,0.00007164695,0.00028223445],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99735326,0.0010864993,0.0003858572,0.0007697182,0.00007596433,0.00032870742],"domain_scores_gemma":[0.99841154,0.0007983577,0.00026277994,0.0001644653,0.000027634538,0.00033521632],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018185856,0.0003796082,0.0010470283,0.00008912488,0.00016280616,0.000072734954,0.00034636233,0.00010531456,0.000006771211],"category_scores_gemma":[0.00079935294,0.00025558268,0.00025404978,0.00021733966,0.00043202384,0.00003891377,0.00021146098,0.0002617431,0.0000064471346],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005942245,0.00008091234,0.0000019012989,0.018109994,0.00034429075,0.00044922912,0.00011140328,0.000010295757,0.17192614,0.0060961666,0.43569472,0.36658072],"study_design_scores_gemma":[0.0011142102,0.000101305865,6.2121615e-7,0.0002035557,0.0006547099,0.000041313353,0.000003831928,0.00025236508,0.00018914342,0.00038043133,0.9968192,0.00023929999],"about_ca_topic_score_codex":0.000007947662,"about_ca_topic_score_gemma":7.07357e-8,"teacher_disagreement_score":0.5611245,"about_ca_system_score_codex":0.0000208991,"about_ca_system_score_gemma":0.0002042878,"threshold_uncertainty_score":0.9999896},"labels":[],"label_agreement":null},{"id":"W3048200443","doi":"10.1124/molpharm.120.000035","title":"Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Universität des Saarlandes; Crohn's and Colitis Foundation","keywords":"Context (archaeology); Drug discovery; Computational biology; Metabolite; Natural product; Biology; Biochemical engineering; Bioinformatics; Biochemistry; Engineering","score_opus":0.02236951837235639,"score_gpt":0.297354095311849,"score_spread":0.2749845769394926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048200443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9511951,0.0015941324,0.0023412493,0.042941745,0.00030971947,0.0013459614,0.00013856523,0.000044724056,0.00008875703],"genre_scores_gemma":[0.94158226,0.00004213882,0.01886347,0.038627144,0.00062235567,0.000007978747,0.00002712983,0.00004808466,0.0001794503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998763,0.00007243146,0.00022931874,0.000510123,0.00008083733,0.0003442718],"domain_scores_gemma":[0.99940807,0.00004286474,0.000060593313,0.000109487555,0.00009048282,0.00028851145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116587216,0.00022100982,0.00047550612,0.0000889569,0.00006809557,0.000024047195,0.00009516316,0.00011492284,0.00015876215],"category_scores_gemma":[0.00010266048,0.00018039276,0.00015559388,0.00021019291,0.00007377052,0.000062448016,0.000095650255,0.00014893596,0.000010244397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016436615,0.00007247102,0.0000056629146,0.00011617532,0.00026375023,0.000029673743,0.00021858499,0.000029643803,0.984861,0.000052581498,0.01087926,0.0018275148],"study_design_scores_gemma":[0.0035555426,0.00024346849,0.000009764768,0.000015719366,0.00083393016,0.000048853097,0.000052984607,0.00063158356,0.91077465,0.0000075587645,0.083630465,0.00019549762],"about_ca_topic_score_codex":0.000019812429,"about_ca_topic_score_gemma":4.169221e-7,"teacher_disagreement_score":0.07408639,"about_ca_system_score_codex":0.00003868791,"about_ca_system_score_gemma":0.000091544265,"threshold_uncertainty_score":0.7356203},"labels":[],"label_agreement":null},{"id":"W3086870866","doi":"10.1124/molpharm.120.000098","title":"Heparin-binding Peptides as Novel Therapies to Stop SARS-CoV-2 Cellular Entry and Infection","year":2020,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"National Institutes of Health; W. Garfield Weston Foundation; Weston Brain Institute","keywords":"Heparin; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Virology; Computational biology; Chemistry; Medicine; Biology; Biochemistry; Infectious disease (medical specialty); Disease; Internal medicine","score_opus":0.07141011932785672,"score_gpt":0.41947821747170716,"score_spread":0.3480680981438504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3086870866","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07615661,0.9180706,0.0007108131,0.00046434434,0.00058558106,0.0023764593,0.00002014307,0.00015601868,0.001459399],"genre_scores_gemma":[0.00409429,0.92265254,0.0002795317,0.07109129,0.000789307,0.00070676114,0.000049489245,0.00024116345,0.000095642674],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970226,0.00033036844,0.00057053624,0.0009584068,0.00044064038,0.00067742297],"domain_scores_gemma":[0.9990534,0.00016772871,0.00019174814,0.00033483465,0.00011806896,0.00013422783],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003566443,0.00063949084,0.0017934827,0.0006346858,0.00013518338,0.00007266568,0.00027509689,0.00049163535,0.00003506712],"category_scores_gemma":[0.0001411775,0.00058121944,0.000478766,0.0007327064,0.0001567206,0.00005894629,0.00041643396,0.0011127702,0.00055136654],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012797434,0.00018065525,0.000059644004,0.00604686,0.0010968489,0.0015011001,0.00022672255,1.17988925e-7,0.7574811,0.000069775175,0.0015464381,0.23166278],"study_design_scores_gemma":[0.0010446851,0.00042471266,0.0000028807503,0.00078930124,0.001274933,0.00039236346,0.000012191108,0.000018191773,0.21021499,0.000012241107,0.78544945,0.00036408246],"about_ca_topic_score_codex":0.00016622368,"about_ca_topic_score_gemma":0.000005148015,"teacher_disagreement_score":0.783903,"about_ca_system_score_codex":0.00033712716,"about_ca_system_score_gemma":0.0006821598,"threshold_uncertainty_score":0.99966395},"labels":[],"label_agreement":null},{"id":"W3092926203","doi":"10.1124/molpharm.120.000100","title":"The Influence of Tobacco Smoke/Nicotine on CYP2A Expression in Human and African Green Monkey Lungs","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; Campbell Family Mental Health Research Institute; Centre for Addiction and Mental Health","keywords":"Nicotine; Smoke; Tobacco smoke; Cigarette smoke; Environmental health; Biology; Toxicology; Geography; Medicine; Neuroscience; Meteorology","score_opus":0.010209457995734117,"score_gpt":0.2901644004581994,"score_spread":0.2799549424624653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092926203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99658525,0.0006374941,0.000041721705,0.0019115264,0.00005724057,0.00037706902,0.000007946321,0.000011478061,0.00037028006],"genre_scores_gemma":[0.9976992,0.00018493392,0.000076255244,0.0018041406,0.00010614432,0.000044834425,0.000014000815,0.00002691489,0.000043559896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852586,0.00025203137,0.0003374625,0.00043631077,0.00014829362,0.00030004143],"domain_scores_gemma":[0.9993768,0.000040481573,0.0001549036,0.00024367869,0.000061293096,0.00012284618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019631711,0.00019486483,0.00023190088,0.000039003666,0.00008608268,0.00000854433,0.00037304813,0.00012953463,0.000015389305],"category_scores_gemma":[0.00010263195,0.00015912905,0.00006393955,0.0001619198,0.00019489972,0.0000039559663,0.0004050147,0.00023913955,0.0000029566822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020942511,0.000086543136,0.007041816,0.000013322212,0.00004393874,0.0000037743591,0.00013502914,0.0005064539,0.99044496,0.000042584514,0.00084290525,0.0006292736],"study_design_scores_gemma":[0.0015174939,0.0006378919,0.0042043775,0.000010284654,0.000025207353,0.0000033655008,0.00006117785,0.000047419548,0.98369753,0.00001882618,0.009614193,0.0001622505],"about_ca_topic_score_codex":0.00005931362,"about_ca_topic_score_gemma":0.000016676695,"teacher_disagreement_score":0.008771287,"about_ca_system_score_codex":0.000014299805,"about_ca_system_score_gemma":0.000040322262,"threshold_uncertainty_score":0.6489094},"labels":[],"label_agreement":null},{"id":"W3116131288","doi":"10.1124/molpharm.120.000146","title":"Transcriptome-Level Interactions between Budesonide and Formoterol Provide Insight into the Mechanism of Action of Inhaled Corticosteroid/Long-Acting β2-Adrenoceptor Agonist Combination Therapy in Asthma","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Formoterol; Budesonide; Asthma; Corticosteroid; Agonist; B2 receptor; Mechanism of action; Pharmacology; Mechanism (biology); Medicine; Receptor; Chemistry; Endocrinology; Internal medicine; Bradykinin; Biochemistry","score_opus":0.043738666983546955,"score_gpt":0.3266598406143972,"score_spread":0.28292117363085023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3116131288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98667014,0.0003403547,0.0094115455,0.0024960907,0.00014514722,0.0008479981,0.000009784738,0.000019721669,0.000059198795],"genre_scores_gemma":[0.99811876,0.00008076465,0.00013757142,0.001495096,0.000046428715,0.00006134367,0.000020764675,0.000024263003,0.000015002187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987336,0.00025152325,0.0004428921,0.00022643493,0.00016997277,0.0001755954],"domain_scores_gemma":[0.9993615,0.00008191859,0.0002358965,0.00009977632,0.0000994418,0.0001214339],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013843075,0.00015704072,0.00035440832,0.00013611541,0.000069401285,0.000009476972,0.000087723194,0.000081979364,0.0000981011],"category_scores_gemma":[0.000048786915,0.0001240669,0.000097155185,0.00020271205,0.00012489849,0.00011414418,0.00003054811,0.00026628503,0.0000014994233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004908661,0.00022657758,0.003555828,0.00014739526,0.00014302508,0.000049716436,0.0028220748,0.000006646049,0.96100926,0.00007013181,0.00002147235,0.031457007],"study_design_scores_gemma":[0.004451253,0.0011285853,0.014836252,0.00004632837,0.00015453101,0.000024383859,0.0004879211,0.00051658734,0.9758294,0.00005680347,0.0023565656,0.00011136524],"about_ca_topic_score_codex":0.000040564504,"about_ca_topic_score_gemma":0.000027295715,"teacher_disagreement_score":0.03134564,"about_ca_system_score_codex":0.000058323636,"about_ca_system_score_gemma":0.00010909819,"threshold_uncertainty_score":0.50593007},"labels":[],"label_agreement":null},{"id":"W3116694340","doi":"10.1124/molpharm.120.000108","title":"Short-Term Acyl-CoA:Cholesterol Acyltransferase Inhibition, Combined with Apoprotein A1 Overexpression, Promotes Atherosclerosis Inflammation Resolution in Mice","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; U.S. Department of Agriculture; NYU Grossman School of Medicine; York University; American Heart Association","keywords":"Inflammation; Lecithin—cholesterol acyltransferase; Chemistry; Cholesterol; Acyltransferase; Acyl-CoA; Sterol O-acyltransferase; Biochemistry; Apolipoprotein B; Internal medicine; Medicine; Lipoprotein; Enzyme","score_opus":0.017821315879871825,"score_gpt":0.2653855391127533,"score_spread":0.2475642232328815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3116694340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98542166,0.00010246581,0.0022439486,0.009885639,0.000108272136,0.001979518,0.000016454227,0.00014430392,0.0000977653],"genre_scores_gemma":[0.9944525,0.00003960627,0.00040310272,0.0041782795,0.00033128916,0.0003486767,0.00015905609,0.00006499891,0.000022534905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776554,0.00029721088,0.0005395047,0.00060296577,0.00035428672,0.0004404996],"domain_scores_gemma":[0.99919266,0.000028707876,0.0001037411,0.00021748227,0.00014049305,0.00031690966],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019869597,0.00034124363,0.00051046466,0.00017071427,0.00008188812,0.00003677434,0.00012914254,0.00021177232,0.0001198969],"category_scores_gemma":[0.000040945484,0.00030149063,0.000100917714,0.00042908324,0.00012440335,0.00026093263,0.00006751713,0.00053419324,0.000031942505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021229489,0.00031299904,0.0045316597,0.00022064446,0.00007298065,0.00011118749,0.0010763276,0.00015152564,0.98951685,0.00002512723,0.00023532537,0.0016224144],"study_design_scores_gemma":[0.0108106965,0.0008647368,0.045002233,0.00030747542,0.00021489133,0.000044036165,0.000036144495,0.00082060875,0.94070625,0.000019416957,0.000882401,0.00029109223],"about_ca_topic_score_codex":0.000034610082,"about_ca_topic_score_gemma":0.000017219774,"teacher_disagreement_score":0.048810594,"about_ca_system_score_codex":0.000076227436,"about_ca_system_score_gemma":0.00008523968,"threshold_uncertainty_score":0.99994373},"labels":[],"label_agreement":null},{"id":"W3189051104","doi":"10.1124/molpharm.121.000336","title":"Pharmacological Characterization of the Imipridone Anticancer Drug ONC201 Reveals a Negative Allosteric Mechanism of Action at the D2 Dopamine Receptor","year":2021,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Institute on Drug Abuse; National Health and Medical Research Council; Medical Research Council; National Institutes of Health","keywords":"Dopamine receptor D2; Allosteric regulation; Dopamine; Pharmacology; Chemistry; Antagonist; Dopamine receptor; Receptor; Biochemistry; Biology; Neuroscience","score_opus":0.01390361225199289,"score_gpt":0.2798660931300027,"score_spread":0.26596248087800983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3189051104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924821,0.00030162136,0.0040869857,0.001337864,0.001121929,0.000473506,0.00006562464,0.000007993641,0.00012232308],"genre_scores_gemma":[0.99618626,0.0006025165,0.00027253,0.0015426442,0.00019594406,0.000072914045,0.000112065856,0.000027416261,0.0009876966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99804014,0.00067587063,0.0004024432,0.00038949694,0.00023104137,0.0002610351],"domain_scores_gemma":[0.99894035,0.000042399075,0.00040432817,0.00027495276,0.00027929648,0.000058657886],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003233627,0.00019859086,0.00029055952,0.000029163619,0.00012549081,0.0000083959585,0.00030212034,0.00014930298,0.001767342],"category_scores_gemma":[0.000060515347,0.000135926,0.00021256618,0.00019441641,0.00017545692,0.000007165313,0.0004030805,0.00016793814,0.0000064263927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022717805,0.00012639051,0.000045499666,0.00003128018,0.00024213472,0.000006336559,0.000073706375,0.000058950664,0.9978902,0.00020880223,0.00052078825,0.0005687755],"study_design_scores_gemma":[0.0008994187,0.00014193963,0.00020891115,0.000015069363,0.00017813436,0.000023689186,0.000057421053,0.00014263227,0.99502784,0.00010322554,0.003059343,0.0001423803],"about_ca_topic_score_codex":0.000008000764,"about_ca_topic_score_gemma":0.0000046791843,"teacher_disagreement_score":0.0038144558,"about_ca_system_score_codex":0.00004518008,"about_ca_system_score_gemma":0.00011242198,"threshold_uncertainty_score":0.99914515},"labels":[],"label_agreement":null},{"id":"W3191668754","doi":"10.1124/molpharm.121.000294","title":"β2-Adrenoceptor Agonists Promote Extracellular Signal-Regulated Kinase 1/2 Dephosphorylation in Human Airway Epithelial Cells by Canonical, cAMP-Driven Signaling Independently of β-Arrestin 2","year":2021,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Formoterol; Kinase; Cell biology; Biology; Phosphorylation; MAPK/ERK pathway; Protein kinase A; Signal transduction; Formoterol Fumarate; Beta adrenergic receptor kinase; Dephosphorylation; Endocrinology; Internal medicine; G protein-coupled receptor; Medicine; Phosphatase","score_opus":0.006845915366163545,"score_gpt":0.25187477028322425,"score_spread":0.2450288549170607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3191668754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864591,0.0029739526,0.009443437,0.000075369164,0.00039249085,0.00050312065,0.00007520032,0.000023621584,0.00005374319],"genre_scores_gemma":[0.9973249,0.00007947916,0.0011279336,0.00018507634,0.00014042675,0.00005693313,0.0006326638,0.00008211529,0.00037049752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99688524,0.00052636553,0.0007745671,0.00086385175,0.00033914836,0.0006108359],"domain_scores_gemma":[0.9988364,0.000027996688,0.0003357303,0.0003388958,0.00025265873,0.00020830112],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004271726,0.00038858224,0.00049584603,0.00011879133,0.00013308377,0.000036311754,0.0003575345,0.00050466834,0.0023057053],"category_scores_gemma":[0.00003299858,0.0004490654,0.00022791774,0.00030721008,0.00013814314,0.0000112427915,0.0002054798,0.0003729382,0.00001019284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013619664,0.00040514703,0.0001535406,0.000051662482,0.00015102686,0.00030204866,0.0001103289,0.007721266,0.98982984,0.000046338246,0.0004303661,0.00066222966],"study_design_scores_gemma":[0.0021950605,0.0003670039,0.000021031172,0.000034866516,0.00009881082,0.000017734676,0.000046929752,0.0010055151,0.9920639,0.000078533005,0.003625962,0.0004446966],"about_ca_topic_score_codex":0.00013194681,"about_ca_topic_score_gemma":0.00004372682,"teacher_disagreement_score":0.010865809,"about_ca_system_score_codex":0.000081755876,"about_ca_system_score_gemma":0.00036823459,"threshold_uncertainty_score":0.9997961},"labels":[],"label_agreement":null},{"id":"W3195502089","doi":"10.1124/molpharm.120.000148","title":"Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77)","year":2021,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Metformin; Endothelial dysfunction; Endocrinology; Internal medicine; Endothelium; Vasodilation; Pharmacology; Oxidative stress; Reactive oxygen species; Endothelial stem cell; Medicine; Diabetes mellitus; Biology; Cell biology; Biochemistry; In vitro","score_opus":0.01905542356807329,"score_gpt":0.28139702514753384,"score_spread":0.26234160157946057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195502089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931336,0.00021727307,0.00032823713,0.00068841275,0.0031938816,0.0011984216,0.00021528003,0.00022233443,0.00080254814],"genre_scores_gemma":[0.9946334,0.00018553081,0.00041738755,0.0025525973,0.0008352457,0.00015995129,0.000083535626,0.00023466919,0.00089768466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99571687,0.0010300375,0.00059314945,0.0011266994,0.00062570814,0.00090755516],"domain_scores_gemma":[0.998243,0.00042420792,0.00037202128,0.0004919996,0.00022056077,0.000248257],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004920219,0.000483104,0.0005674142,0.00012707742,0.001285118,0.00019517032,0.0008335791,0.00034015073,0.009694834],"category_scores_gemma":[0.0005339589,0.0004369644,0.00059216603,0.00050608156,0.00022682073,0.00027044883,0.00039976888,0.00069698243,0.00042415946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003014911,0.00056068477,0.000009532197,0.000025115645,0.00037976285,0.00006492488,0.0006809808,0.0001154755,0.989394,0.0012639883,0.0050473814,0.002156666],"study_design_scores_gemma":[0.0031550545,0.00038454783,0.000005740624,0.000025129037,0.000331128,0.000021957601,0.000543097,0.00087070616,0.8545059,0.0001512457,0.13958465,0.00042083065],"about_ca_topic_score_codex":0.00004681809,"about_ca_topic_score_gemma":0.0000073185806,"teacher_disagreement_score":0.13488808,"about_ca_system_score_codex":0.00024791784,"about_ca_system_score_gemma":0.00013833331,"threshold_uncertainty_score":0.9998082},"labels":[],"label_agreement":null},{"id":"W3197181042","doi":"10.1124/molpharm.121.000301","title":"Therapeutic Neuroprotection by an Engineered Neurotrophin that Selectively Activates Tropomyosin Receptor Kinase (Trk) Family Neurotrophin Receptors but Not the p75 Neurotrophin Receptor","year":2021,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital; Simon Fraser University","funders":"Canadian Institutes of Health Research; Consortium canadien en neurodégénérescence associée au vieillissement; U.S. Department of Defense","keywords":"Trk receptor; Tropomyosin receptor kinase A; Neurotrophin; Low-affinity nerve growth factor receptor; Tropomyosin receptor kinase C; Tropomyosin receptor kinase B; Neuroprotection; Biology; Nerve growth factor; Cell biology; Receptor; Neurotrophic factors; Neuroscience; Growth factor; Biochemistry; Platelet-derived growth factor receptor","score_opus":0.03052795957162173,"score_gpt":0.27698069043238166,"score_spread":0.24645273086075992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197181042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783135,0.00046008345,0.00356909,0.00930222,0.0058240453,0.0017824764,0.00013493745,0.0005184896,0.0000951238],"genre_scores_gemma":[0.9781622,0.0006188363,0.00026700654,0.01814169,0.00072945195,0.00059280806,0.00009162662,0.00026456424,0.0011318125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98930335,0.005881683,0.00073515176,0.002056336,0.0008462231,0.0011772397],"domain_scores_gemma":[0.9975953,0.0004074578,0.00043956673,0.0008969841,0.0002588607,0.00040182925],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037823798,0.0009052899,0.00063897547,0.00028239255,0.0010674366,0.00034223986,0.0010646473,0.000363533,0.000541003],"category_scores_gemma":[0.00041446346,0.0007743886,0.00037589084,0.0014597054,0.00048244232,0.0006754635,0.00026063836,0.0018081695,0.00018149836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009448544,0.0006361592,0.0000059473405,0.00002693713,0.00005954589,0.00036194827,0.0001345542,0.002879226,0.98384285,0.0003059504,0.0056106215,0.005191423],"study_design_scores_gemma":[0.0016598791,0.0011768206,0.00016008886,0.0000102479235,0.0001206448,0.00020618044,0.000046747748,0.0036945161,0.95961803,0.00009913789,0.03247639,0.00073133025],"about_ca_topic_score_codex":0.00009432597,"about_ca_topic_score_gemma":0.0000038314897,"teacher_disagreement_score":0.02686577,"about_ca_system_score_codex":0.00021226148,"about_ca_system_score_gemma":0.00025732987,"threshold_uncertainty_score":0.9994707},"labels":[],"label_agreement":null},{"id":"W3197231870","doi":"10.1124/molpharm.121.000290","title":"High-Content Single-Cell Förster Resonance Energy Transfer Imaging of Cultured Striatal Neurons Reveals Novel Cross-Talk in the Regulation of Nuclear Signaling by Protein Kinase A and Extracellular Signal-Regulated Kinase 1/2","year":2021,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Weston Brain Institute; Faculty of Medicine, McGill University; McGill University","keywords":"Medium spiny neuron; Förster resonance energy transfer; High-content screening; Cytoplasm; Cell biology; Biology; Intracellular; Signal transduction; Extracellular; Cell signaling; Kinase; Cell; Biophysics; Neuroscience; Biochemistry; Dopamine; Striatum; Fluorescence","score_opus":0.011088957045587693,"score_gpt":0.24904407494143543,"score_spread":0.23795511789584775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197231870","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96916354,0.005253087,0.024795905,0.00018825759,0.00003317743,0.00047177376,0.00007284117,0.000010829233,0.000010594576],"genre_scores_gemma":[0.9941441,0.00005256795,0.005172525,0.000317346,0.000020228235,0.00005350287,0.00013785313,0.000041971427,0.000059905382],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99806947,0.0003356874,0.0005621596,0.00054512377,0.00016418954,0.00032337388],"domain_scores_gemma":[0.99934584,0.0000232142,0.00015421052,0.00027653397,0.00015220721,0.000047976137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026252048,0.00024175068,0.00031165945,0.00007896642,0.000043119373,0.00001971457,0.00023439502,0.00017967285,0.000022903267],"category_scores_gemma":[0.00003321733,0.00023287346,0.00009281324,0.00024905874,0.00027380273,0.000019760973,0.00009401906,0.00018592128,1.0941859e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037189695,0.00048739853,0.00018729713,0.00006282818,0.000016691094,0.00009943362,0.00011165752,0.000375471,0.99768794,0.0001409614,0.000055902558,0.00040250833],"study_design_scores_gemma":[0.0022838467,0.00020426001,0.0003459387,0.00007450369,0.000031202668,0.000019803145,0.00006117384,0.00034372695,0.99565506,0.00006062067,0.0007114807,0.00020840165],"about_ca_topic_score_codex":0.000064758766,"about_ca_topic_score_gemma":0.00001098675,"teacher_disagreement_score":0.024980564,"about_ca_system_score_codex":0.00002999052,"about_ca_system_score_gemma":0.000045135326,"threshold_uncertainty_score":0.9496304},"labels":[],"label_agreement":null},{"id":"W4240876169","doi":"10.1124/mol.120.000089","title":"Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; University of Ottawa","funders":"Canadian Institutes of Health Research; Alberta Innovates; Canada Research Chairs","keywords":"Metabotropic glutamate receptor 5; Metabotropic glutamate receptor; Metabotropic glutamate receptor 1; Neuroscience; Glutamatergic; Metabotropic glutamate receptor 7; Metabotropic glutamate receptor 6; Metabotropic glutamate receptor 3; Neurotransmission; Metabotropic glutamate receptor 8; Glutamate receptor; Biology; Receptor; Biochemistry","score_opus":0.04140079866741166,"score_gpt":0.3287282348801419,"score_spread":0.28732743621273027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240876169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98797864,0.00013392606,0.00046047603,0.009697349,0.00051657716,0.00084011356,0.000069827714,0.00020493916,0.0000981359],"genre_scores_gemma":[0.9664581,0.00026123086,0.00012018471,0.032643713,0.00015831669,0.00025897275,0.000004867661,0.000063112064,0.000031523407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966781,0.00068423065,0.0003929444,0.0011428734,0.00033664767,0.00076519395],"domain_scores_gemma":[0.9989898,0.00018784741,0.00012723521,0.00019129344,0.00004414993,0.00045963982],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018769404,0.00033134402,0.00035983737,0.00015894785,0.0004278321,0.00007312991,0.00056392653,0.000101175356,0.0004984287],"category_scores_gemma":[0.00012367907,0.0003162074,0.00012154012,0.0006135052,0.00038087208,0.0001858257,0.00015911595,0.00068489177,0.00019837247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014508613,0.00019367493,0.0002741953,0.000022459244,0.000012885016,0.0008939845,0.000097640164,0.00037317773,0.9963339,0.00027168728,0.00048757644,0.0008937111],"study_design_scores_gemma":[0.001111972,0.00043299145,0.0005075787,0.0000034535403,0.00014271696,0.000044310047,0.0000064646683,0.0014901914,0.99091756,0.000026987549,0.0050336285,0.00028216495],"about_ca_topic_score_codex":0.000002245696,"about_ca_topic_score_gemma":5.2245603e-8,"teacher_disagreement_score":0.022946363,"about_ca_system_score_codex":0.00002524336,"about_ca_system_score_gemma":0.000060409457,"threshold_uncertainty_score":0.999929},"labels":[],"label_agreement":null},{"id":"W4283792693","doi":"10.1124/molpharm.122.000497","title":"Michaelis-Menten Quantification of Ligand Signaling Bias Applied to the Promiscuous Vasopressin V2 Receptor","year":2022,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Ligand (biochemistry); Agonist; Vasopressin; G protein-coupled receptor; Receptor; Affinities; Intrinsic activity; Chemistry; Biology; Biophysics; Biochemistry; Endocrinology","score_opus":0.020293417456215813,"score_gpt":0.2698263718320222,"score_spread":0.24953295437580636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283792693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784844,0.0008298118,0.017876264,0.0010504179,0.0006531952,0.00082741195,0.00004424916,0.000017715098,0.00021651667],"genre_scores_gemma":[0.9958548,0.000028605225,0.001208453,0.0018027624,0.00017873022,0.00047208517,0.00016916242,0.00004188986,0.00024354213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983666,0.00028621635,0.00034258858,0.00045671174,0.00024920373,0.00029866144],"domain_scores_gemma":[0.9992934,0.000021109723,0.00019524149,0.00032038876,0.00008638609,0.00008349381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067402935,0.00017834574,0.00020799953,0.00007834929,0.00024962678,0.000017604405,0.00048371512,0.00007879148,0.0005423596],"category_scores_gemma":[0.000027558257,0.00015579631,0.00011934731,0.0002098634,0.000049229602,0.0000021963367,0.00034962982,0.00017839913,0.000015238574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002444241,0.00010772047,0.000016539558,0.0000141025275,0.00012728818,0.0000035711735,0.00024304067,0.013609415,0.97793543,0.00019769702,0.0062455,0.0012552745],"study_design_scores_gemma":[0.0005423168,0.00028585774,0.00000667971,0.0000030064077,0.00005482097,0.000008242773,0.00022581518,0.00020832928,0.9061536,0.000039414568,0.09230819,0.00016369461],"about_ca_topic_score_codex":0.000016016766,"about_ca_topic_score_gemma":0.0000015282545,"teacher_disagreement_score":0.08606269,"about_ca_system_score_codex":0.000027284585,"about_ca_system_score_gemma":0.00008200622,"threshold_uncertainty_score":0.6353189},"labels":[],"label_agreement":null},{"id":"W4310578986","doi":"10.1124/molpharm.122.000595","title":"Cisplatin Toxicity Is Mediated by Direct Binding to Toll-Like Receptor 4 through a Mechanism That Is Distinct from Metal Allergens","year":2022,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Stollery Children’s Hospital Foundation; Children's Hospital Foundation; University of Alberta; Canada Research Chairs; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Cisplatin; TLR4; Chemistry; Toll-like receptor; Proinflammatory cytokine; Pharmacology; Receptor; Biochemistry; Biology; Inflammation; Immunology; Innate immune system; Chemotherapy","score_opus":0.020711715897756337,"score_gpt":0.29148638924136316,"score_spread":0.27077467334360683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310578986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97872955,0.00029487276,0.0020492508,0.014310649,0.0011870542,0.0011664311,0.001346945,0.00022539771,0.0006898403],"genre_scores_gemma":[0.95226914,0.000044634628,0.0017401298,0.043504667,0.00015706956,0.00025242186,0.00092384766,0.00012789309,0.0009802061],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99689543,0.00039995875,0.00044057358,0.00091316376,0.0007391713,0.0006117222],"domain_scores_gemma":[0.9988488,0.00016481652,0.00021311805,0.00038204342,0.00006614953,0.0003250877],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00030545503,0.00041398735,0.00067284756,0.00017317865,0.00030614564,0.000020801479,0.00032468856,0.00019008442,0.029065857],"category_scores_gemma":[0.00006975509,0.00045800634,0.00024663683,0.000620471,0.000059950085,0.00008764726,0.0003310189,0.0005979956,0.00027944302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029191867,0.0003019645,0.000108466134,0.000012620062,0.0007482376,0.00015736658,0.0024501646,0.0000047008816,0.8821597,0.000009641518,0.113476835,0.00027836193],"study_design_scores_gemma":[0.002863691,0.0004336175,0.000048840342,0.000010318354,0.00039473668,0.00003399539,0.00023169277,0.0003694876,0.9332989,0.00012408002,0.06179675,0.00039390766],"about_ca_topic_score_codex":0.00021545548,"about_ca_topic_score_gemma":0.000011406564,"teacher_disagreement_score":0.051680088,"about_ca_system_score_codex":0.00061059615,"about_ca_system_score_gemma":0.00014040347,"threshold_uncertainty_score":0.99978715},"labels":[],"label_agreement":null},{"id":"W4310601252","doi":"10.1124/molpharm.122.000606","title":"Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in Mice Carrying the Human Pathogenic Mutation DRD2","year":2022,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institutes of Health; York University; Rijksuniversiteit Groningen; Oregon Health and Science University; New York University Abu Dhabi; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Office of Research and Development; U.S. Department of Veterans Affairs","keywords":"Dopamine receptor D2; Nucleus accumbens; Striatum; Dopamine; Mesolimbic pathway; Internal medicine; Sulpiride; Endocrinology; Dopamine receptor D1; Biology; Chemistry; Dopaminergic; Medicine; Ventral tegmental area","score_opus":0.021942658317726328,"score_gpt":0.27906494100130363,"score_spread":0.2571222826835773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310601252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986152,0.0002983869,0.000053776486,0.00036315396,0.00033159446,0.0002440775,0.0000068240697,0.00003455165,0.000052416643],"genre_scores_gemma":[0.9978255,0.000044678192,0.00002363939,0.0019083978,0.000024154093,0.000103111284,0.0000014190296,0.000015156356,0.000053932385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986492,0.00038917153,0.00017000493,0.00035079615,0.00017560847,0.00026521416],"domain_scores_gemma":[0.9996685,0.00015109051,0.00005706269,0.000069458045,0.000006322496,0.00004759243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026720137,0.0001136218,0.00010902688,0.00011054447,0.000482761,0.000034240627,0.00017435919,0.000022037206,0.000056926234],"category_scores_gemma":[0.000037621692,0.000100406956,0.000023971736,0.00022294387,0.00010901776,0.00012428068,0.00022933251,0.0003007793,9.650056e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013682418,0.000015276759,0.00004215852,0.000012869792,9.278595e-7,0.00021419153,0.00088222575,0.0026058974,0.99586046,0.00012468333,0.000030449391,0.00019717152],"study_design_scores_gemma":[0.00044753676,0.000073721865,0.00010654717,0.0000054626066,0.000008583354,0.00015686703,0.00024120012,0.0031965117,0.9949883,0.00008076917,0.00058025063,0.000114201786],"about_ca_topic_score_codex":0.000015283684,"about_ca_topic_score_gemma":7.3960877e-7,"teacher_disagreement_score":0.0015452438,"about_ca_system_score_codex":0.000029362553,"about_ca_system_score_gemma":0.000013927957,"threshold_uncertainty_score":0.4094477},"labels":[],"label_agreement":null},{"id":"W4383506552","doi":"10.1124/molpharm.123.000708","title":"Differential Effects of Remdesivir and Lumacaftor on Homomeric and Heteromeric hERG Channels","year":2023,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; American Society for Pharmacology and Experimental Therapeutics","keywords":"hERG; Homomeric; Cell biology; Chemistry; Patch clamp; Ion channel; Mutant; Pharmacology; Protein subunit; Potassium channel; Biophysics; Biology; Biochemistry; Gene","score_opus":0.005172642752685737,"score_gpt":0.2688884004578795,"score_spread":0.26371575770519373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383506552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979424,0.00061811565,0.00006202354,0.00040560064,0.00045675616,0.00036654316,0.0000023299872,0.000057924983,0.00008833071],"genre_scores_gemma":[0.99805623,0.00062828144,0.000018384491,0.0008527496,0.0001597683,0.00005886843,0.00001247584,0.000023006876,0.00019024793],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909925,0.00013632432,0.0001299564,0.0002778522,0.00008843463,0.00026816005],"domain_scores_gemma":[0.999591,0.00012674538,0.000049877868,0.00010862164,0.000021101363,0.00010266452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003707411,0.0001476996,0.00040612262,0.00017748482,0.000046696172,0.0000031201428,0.0000319566,0.00009539981,0.00003974341],"category_scores_gemma":[0.000026192802,0.00013287066,0.000082533705,0.00022810412,0.00017895664,0.000015115404,0.00006600612,0.0001828976,0.000019237737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035520064,0.000061639286,0.0001149165,0.0002201872,0.00023790743,0.0016616322,0.00005151533,0.000014723496,0.99231297,0.00004734557,0.00073816243,0.0041837865],"study_design_scores_gemma":[0.0035612986,0.0022000885,0.02048604,0.000043499775,0.00035484004,0.0003578864,0.0000067215574,0.00047520225,0.9716881,0.000121166,0.00053839,0.00016678883],"about_ca_topic_score_codex":0.0000037393206,"about_ca_topic_score_gemma":5.2509076e-8,"teacher_disagreement_score":0.020624906,"about_ca_system_score_codex":0.000012415173,"about_ca_system_score_gemma":0.000016965103,"threshold_uncertainty_score":0.54183084},"labels":[],"label_agreement":null},{"id":"W4384922461","doi":"10.1124/molpharm.123.000710","title":"Atypical Chemokine Receptor 3 “Senses” CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation","year":2023,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; University of California, San Diego; National Cancer Institute; National Institutes of Health; Université de Montréal; National Institute of Allergy and Infectious Diseases; Augusta University; Walther Cancer Foundation; Purdue University; National Institute of General Medical Sciences; American Heart Association","keywords":"G protein-coupled receptor kinase; G protein-coupled receptor; Chemokine receptor; C-C chemokine receptor type 6; Beta adrenergic receptor kinase; Cell biology; Chemistry; Arrestin; Receptor; Phosphorylation; C-C chemokine receptor type 7; Biology; Signal transduction; Biochemistry; Chemokine","score_opus":0.022045186857372237,"score_gpt":0.31547863628927714,"score_spread":0.2934334494319049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384922461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98316294,0.00021690206,0.0019226985,0.010345548,0.0011664967,0.00093193393,0.000020948906,0.0005646328,0.0016678924],"genre_scores_gemma":[0.98816174,0.00034310127,0.002146563,0.004051984,0.0014138154,0.00015987066,0.0012570255,0.00014042889,0.0023254496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971843,0.00014354935,0.000609913,0.0007779224,0.0005409852,0.00074335956],"domain_scores_gemma":[0.9986921,0.00015386654,0.00022233799,0.00036715984,0.00028533392,0.0002792086],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000384194,0.00043789903,0.00065643503,0.00023791126,0.0001747322,0.00002774859,0.00018023106,0.00041810318,0.007430054],"category_scores_gemma":[0.0002405089,0.0004370457,0.00030126784,0.0010364938,0.00015026597,0.00015861685,0.00015098393,0.0006442185,0.0011962255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011245438,0.00027734955,0.00032225743,0.00011248037,0.0001942326,0.0000778088,0.00028387646,0.00010623192,0.8970494,0.0001090252,0.09387797,0.0064648194],"study_design_scores_gemma":[0.0036515845,0.00025245044,0.00059685303,0.000072090974,0.00018289028,0.000026298641,0.000065034445,0.0010603992,0.8223324,0.00010398906,0.17131095,0.0003450853],"about_ca_topic_score_codex":0.000024539997,"about_ca_topic_score_gemma":5.407674e-7,"teacher_disagreement_score":0.07743298,"about_ca_system_score_codex":0.00037173877,"about_ca_system_score_gemma":0.00016042007,"threshold_uncertainty_score":0.99980813},"labels":[],"label_agreement":null},{"id":"W4387805006","doi":"10.1124/molpharm.123.000740","title":"Synergy between Interleukin-1β, Interferon-γ, and Glucocorticoids to Induce TLR2 Expression Involves NF-κB, STAT1, and the Glucocorticoid Receptor","year":2023,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"TLR2; STAT1; STAT3; Janus kinase; Glucocorticoid receptor; Downregulation and upregulation; Glucocorticoid; Receptor; Signal transduction; Chemistry; Endocrinology; Biology; Internal medicine; Medicine; Cell biology; Innate immune system; Biochemistry","score_opus":0.010357507694317822,"score_gpt":0.2669979346571801,"score_spread":0.25664042696286227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387805006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920344,0.0018987041,0.00059305603,0.003438689,0.00096580444,0.00079687306,0.000011504171,0.0001300828,0.00013089142],"genre_scores_gemma":[0.99667466,0.00036564138,0.00004796911,0.0013197733,0.000064675274,0.0002124728,0.00013068428,0.000037784717,0.0011463675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974248,0.0010130631,0.00049595995,0.0004724997,0.00006355558,0.0005301505],"domain_scores_gemma":[0.9989061,0.00052177196,0.00015102205,0.0002862379,0.0000704381,0.00006442886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062465767,0.00028014247,0.00045952943,0.00030065226,0.00021909871,0.000040957537,0.00029555822,0.00027059807,0.00024016392],"category_scores_gemma":[0.00016343324,0.00021201087,0.0000787916,0.00031748833,0.0004724304,0.0001297035,0.00063810917,0.00043418826,0.0006195614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00140914,0.000024024837,0.0003522306,0.000032461907,0.00025198428,0.000018325616,0.002156044,0.0000141736855,0.97989494,0.00038818468,0.003711292,0.011747199],"study_design_scores_gemma":[0.00395734,0.00040901246,0.0015168737,0.000047696034,0.00011109671,0.000029008497,0.0005094932,0.000028296472,0.94611233,0.00015590299,0.046880823,0.0002421458],"about_ca_topic_score_codex":0.00005723453,"about_ca_topic_score_gemma":0.0000036042427,"teacher_disagreement_score":0.04316953,"about_ca_system_score_codex":0.000060322203,"about_ca_system_score_gemma":0.00008309439,"threshold_uncertainty_score":0.8645552},"labels":[],"label_agreement":null},{"id":"W4403673372","doi":"10.1124/molpharm.124.000958","title":"Modeling the contribution of cardiac fibroblasts in dilated cardiomyopathy using induced pluripotent stem cells","year":2024,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Courtois Foundation","keywords":"Induced pluripotent stem cell; Dilated cardiomyopathy; Cardiomyopathy; Stem cell; Human Induced Pluripotent Stem Cells; Cell biology; Medicine; Biology; Cardiology; Embryonic stem cell; Heart failure; Genetics; Gene","score_opus":0.04376752209409857,"score_gpt":0.3462485846901086,"score_spread":0.30248106259601004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403673372","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.053792972,0.94109344,0.000535133,0.000041057367,0.0020914832,0.0023146148,0.000057188936,0.00004546002,0.00002864837],"genre_scores_gemma":[0.14263326,0.85668176,0.000052141775,0.000052765943,0.00029850425,0.00008451499,0.00006903943,0.00011648113,0.000011519682],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9965083,0.0007394357,0.0011867363,0.00065292744,0.00038277314,0.0005298021],"domain_scores_gemma":[0.9989236,0.00007082564,0.000253617,0.00041403674,0.00021204425,0.00012589472],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007185212,0.00055529946,0.003061841,0.00048820837,0.00005559882,0.000023773646,0.000190515,0.0006322559,0.0000068394666],"category_scores_gemma":[0.000011016424,0.00037431114,0.001936241,0.0007891389,0.00006389005,0.000031130105,0.00026536157,0.0011711594,0.000015876763],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014504099,0.00014212675,0.000003224484,0.020770008,0.004670575,0.0004407173,0.00020206801,0.059443846,0.73850447,0.000048795628,0.00015566351,0.17547345],"study_design_scores_gemma":[0.0031417694,0.00049555727,0.0000017135883,0.054525543,0.072569765,0.0007002805,0.00016984857,0.5655845,0.060798943,0.000033480548,0.24008468,0.0018939511],"about_ca_topic_score_codex":0.00010842658,"about_ca_topic_score_gemma":9.585063e-7,"teacher_disagreement_score":0.6777055,"about_ca_system_score_codex":0.000542613,"about_ca_system_score_gemma":0.00067101605,"threshold_uncertainty_score":0.9998709},"labels":[],"label_agreement":null},{"id":"W4405985381","doi":"10.1016/s0026-895x(24)12330-9","title":"Heterogeneous Nuclear Ribonucleoprotein A1 and Regulation of the Xenobiotic-Inducible Gene Cyp2a5","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Xenobiotic; Gene; Ribonucleoprotein; Chemistry; Cell biology; Computational biology; Biology; Genetics; Biochemistry; RNA; Enzyme","score_opus":0.056557291679361237,"score_gpt":0.3442259826809943,"score_spread":0.28766869100163306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405985381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98670983,0.0052017327,0.00006415682,0.0020879323,0.0018003953,0.00082804525,0.00005973024,0.00007255203,0.003175629],"genre_scores_gemma":[0.9927441,0.00080436416,0.0003805028,0.005212696,0.00023608987,0.000036435253,0.0000058440046,0.00006684175,0.00051310874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971888,0.00087784993,0.0005361513,0.00053661,0.00025085322,0.00060972874],"domain_scores_gemma":[0.99881035,0.00009528778,0.00029498164,0.00038742635,0.00012951517,0.0002824149],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00048307772,0.0003438069,0.00041851387,0.0001499373,0.00033816035,0.000019627905,0.00052208314,0.00038891815,0.0043590646],"category_scores_gemma":[0.00003913217,0.00029794688,0.0002007655,0.00036002343,0.0005357784,0.00007146241,0.00037342613,0.0006843003,0.00011708283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096356285,0.0003175453,0.00027715604,0.00004414871,0.00027837837,0.0000521662,0.00033752783,0.0019985402,0.9810454,0.0007150487,0.0021374198,0.012700316],"study_design_scores_gemma":[0.0021747467,0.00008987392,0.0007786566,0.0000058636438,0.00043059952,0.00015136553,0.00001026845,0.016514478,0.84631115,0.00033140322,0.13292475,0.00027682018],"about_ca_topic_score_codex":0.000016846425,"about_ca_topic_score_gemma":0.000001941621,"teacher_disagreement_score":0.13473421,"about_ca_system_score_codex":0.000042254196,"about_ca_system_score_gemma":0.00003502743,"threshold_uncertainty_score":0.99994725},"labels":[],"label_agreement":null},{"id":"W4405989339","doi":"10.1016/s0026-895x(24)26413-0","title":"Inhibition of c-myc Expression in Cells by Targeting an RNA-Protein Interaction Using Antisense Oligonucleotides","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Oligonucleotide; RNA; Molecular biology; Antisense RNA; Protein expression; Biology; Cell biology; Chemistry; Computational biology; Biochemistry; Gene","score_opus":0.006789737179315195,"score_gpt":0.26933911141346606,"score_spread":0.26254937423415087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405989339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983413,0.00031263096,0.00044635203,0.000024840148,0.000106369946,0.00017091303,0.000017604438,0.00001366043,0.00056633033],"genre_scores_gemma":[0.9978891,0.00008999223,0.001435812,0.00021864915,0.00009476274,0.000011308711,0.0001460509,0.000033035594,0.00008131683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987759,0.00016472964,0.00032009662,0.00037482925,0.000099878715,0.00026456048],"domain_scores_gemma":[0.999581,0.000005084871,0.00012394611,0.00016645559,0.00004260026,0.000080944315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013921107,0.00017274922,0.00017910807,0.0000514661,0.000044611996,0.000009723902,0.00011576463,0.00019645075,0.00038777036],"category_scores_gemma":[0.000009894942,0.00019470546,0.00006880825,0.00009487604,0.000082752274,0.000015797823,0.000057325007,0.00015121346,0.0000058291885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022490576,0.00019918954,0.00004200718,0.000031387543,0.00001673074,0.000043115335,0.000044718643,0.0009929715,0.996137,5.4232635e-7,0.00088577316,0.0013816417],"study_design_scores_gemma":[0.0008585608,0.00012669337,0.000010344117,0.00003368675,0.000017971703,0.000012675326,0.00006442256,0.0008880847,0.9955897,0.000013260543,0.0021935005,0.00019114988],"about_ca_topic_score_codex":0.000032687403,"about_ca_topic_score_gemma":0.0000011237822,"teacher_disagreement_score":0.0013077274,"about_ca_system_score_codex":0.000025780197,"about_ca_system_score_gemma":0.000027273518,"threshold_uncertainty_score":0.7939858},"labels":[],"label_agreement":null},{"id":"W4405990412","doi":"10.1016/s0026-895x(24)12685-5","title":"Receptor Binding and Agonist Efficacy: New Insights from Mutants of the Thrombin Protease-Activated Receptor-1 (PAR-1)","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Agonist; Thrombin receptor; Protease-activated receptor 2; Thrombin; Receptor; Protease-activated receptor; Chemistry; Protease; Mutant; Biochemistry; Cell biology; Enzyme-linked receptor; Biology; Enzyme; Immunology; Gene","score_opus":0.019848168029541337,"score_gpt":0.27964327050490345,"score_spread":0.25979510247536214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405990412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951541,0.00028253638,0.000059594568,0.0019461836,0.00046545462,0.0009953397,0.000022635375,0.000068527566,0.0010056284],"genre_scores_gemma":[0.9971344,0.00005899327,0.0007998769,0.0013527995,0.00010732045,0.000023094912,0.00005462434,0.000038861748,0.00043001267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985857,0.00025053797,0.00032400916,0.0003705709,0.00024153444,0.00022767551],"domain_scores_gemma":[0.99928343,0.000049736023,0.0001413279,0.00026745204,0.000051535968,0.00020653055],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007313551,0.00020955081,0.00040725822,0.000076639706,0.00013015074,0.000014148582,0.00015165027,0.0001784434,0.00594922],"category_scores_gemma":[0.000031216172,0.00016199575,0.00010293176,0.00035667024,0.0001545858,0.0000510103,0.00006293122,0.00028136635,0.0001271254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029602353,0.0002838239,0.00014975121,0.000015945361,0.00028665143,0.000014177877,0.00026325177,0.0000068967693,0.9914432,0.00012813226,0.0021804892,0.004931615],"study_design_scores_gemma":[0.004613133,0.00023232332,0.0037016536,0.000074452975,0.00027493236,0.000016104079,0.00002317237,0.00008039595,0.98275816,0.00019811108,0.007872301,0.00015523614],"about_ca_topic_score_codex":0.00009397321,"about_ca_topic_score_gemma":0.0000019793695,"teacher_disagreement_score":0.008685057,"about_ca_system_score_codex":0.000045984416,"about_ca_system_score_gemma":0.00015809278,"threshold_uncertainty_score":0.9949595},"labels":[],"label_agreement":null},{"id":"W4405990882","doi":"10.1016/s0026-895x(24)12580-1","title":"Tripterygium wilfordii Hook F Extract Suppresses Proinflammatory Cytokine-Induced Expression of Matrix Metalloproteinase Genes in Articular Chondrocytes by Inhibiting Activating Protein-1 and Nuclear Factor-κB Activities","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Natural Compounds in Disease Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Tripterygium wilfordii; Proinflammatory cytokine; Matrix metalloproteinase; Chemistry; Cytokine; Metalloproteinase; Tripterygium; Gene expression; Cell biology; Immunology; Gene; Molecular biology; Medicine; Biology; Inflammation; Biochemistry; Pathology","score_opus":0.012410615395696545,"score_gpt":0.2931703597517759,"score_spread":0.28075974435607937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405990882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994402,0.0032689504,0.00006128458,0.00028013863,0.00007778001,0.0016549869,0.000017536991,0.00010322212,0.00013411476],"genre_scores_gemma":[0.99765474,0.00008003379,0.00162625,0.00010039583,0.00007052946,0.00026820975,0.000024593157,0.000074769734,0.00010047528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977583,0.00027817162,0.0005439708,0.0005390903,0.00037590472,0.0005045175],"domain_scores_gemma":[0.99906564,0.0000922269,0.0003205165,0.00023653041,0.00008098206,0.00020410352],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015711863,0.000400476,0.00066965027,0.00034628992,0.00010503266,0.000028731829,0.0001330928,0.0001885813,0.00021995716],"category_scores_gemma":[0.000090287955,0.00035785243,0.00014905901,0.00026592385,0.00012640962,0.00032525393,0.0001796142,0.00042512504,0.0000026422254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011761453,0.00047927044,0.0007853286,0.00031891285,0.00016833877,0.0017218029,0.0002467623,0.000008719181,0.9913584,0.000009547593,0.00006110007,0.0036656617],"study_design_scores_gemma":[0.004355847,0.00042417232,0.00055650144,0.0002631017,0.00015443299,0.00021462848,0.00026081206,0.00015663671,0.9925323,0.000027707856,0.00075612223,0.0002977212],"about_ca_topic_score_codex":0.00003790896,"about_ca_topic_score_gemma":0.0000015749295,"teacher_disagreement_score":0.0033679404,"about_ca_system_score_codex":0.00018287358,"about_ca_system_score_gemma":0.00009790566,"threshold_uncertainty_score":0.99988735},"labels":[],"label_agreement":null},{"id":"W4405991089","doi":"10.1016/s0026-895x(24)12256-0","title":"Glucuronidation of the Nonsteroidal Antiestrogen EM-652 (SCH 57068), by Human and Monkey Steroid Conjugating UDP-Glucuronosyltransferase Enzymes","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Glucuronidation; Steroid; Chemistry; Enzyme; Antiestrogen; Glucuronosyltransferase; Nonsteroidal; Pharmacology; Hypoprothrombinemia; Biochemistry; Internal medicine; Medicine; Microsome; Hormone; Tamoxifen","score_opus":0.0033223964127046058,"score_gpt":0.24006795178849613,"score_spread":0.23674555537579153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405991089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99229896,0.0056649433,0.00070329366,0.0002510865,0.00021586932,0.0004642382,0.000030097903,0.000018636327,0.00035287585],"genre_scores_gemma":[0.99846905,0.00041706357,0.00008384285,0.00058733125,0.000081079226,0.000031284864,0.00011409748,0.000039803857,0.0001764222],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838763,0.00033152555,0.0003379194,0.00041966356,0.00015432313,0.0003689288],"domain_scores_gemma":[0.9993758,0.000019241217,0.00014979481,0.00027169645,0.00006881388,0.00011461541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001698521,0.0002607251,0.00024298448,0.000050377083,0.00018844297,0.0000240427,0.00027653849,0.0002486776,0.000049393147],"category_scores_gemma":[0.000018261553,0.00022136905,0.00013044289,0.00013106647,0.00025708968,0.000009991528,0.00016083379,0.00024572067,0.0000037858124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010560597,0.000108276356,0.005208098,0.000025588248,0.00019546127,0.000020810614,0.000078190445,0.000075224314,0.99171287,0.00006776677,0.001003058,0.00139905],"study_design_scores_gemma":[0.0018310652,0.00048877235,0.00062649196,0.00001342392,0.00014176551,0.000103245206,0.000054321958,0.00012366811,0.991522,0.000020102842,0.0048533683,0.00022174604],"about_ca_topic_score_codex":0.000024159619,"about_ca_topic_score_gemma":0.0000049748573,"teacher_disagreement_score":0.006170116,"about_ca_system_score_codex":0.000012390323,"about_ca_system_score_gemma":0.000053330692,"threshold_uncertainty_score":0.90271676},"labels":[],"label_agreement":null},{"id":"W4405992922","doi":"10.1016/s0026-895x(24)12829-5","title":"Changes in Agonist Concentration Dependence That Are a Function of Duration of Exposure Suggest N-Methyl-d-aspartate Receptor Nonsaturation during Synaptic Stimulation","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Agonist; Stimulation; Duration (music); Chemistry; Receptor; Neuroscience; Endocrinology; Internal medicine; Biology; Medicine; Biochemistry; Physics","score_opus":0.03887470179181112,"score_gpt":0.32156381993512184,"score_spread":0.2826891181433107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405992922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99733037,0.00006957079,0.00035609494,0.00068348,0.00068639853,0.0007766553,0.000012617925,0.000039357004,0.00004548656],"genre_scores_gemma":[0.99888486,0.0004840565,0.000022707589,0.0003991457,0.00004579128,0.0000897887,0.000007204627,0.000019659623,0.000046767425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973085,0.00085081503,0.00043911042,0.0005598274,0.00044210773,0.00039967144],"domain_scores_gemma":[0.9988988,0.00025534863,0.00046268542,0.00016925466,0.00013233784,0.00008156509],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003368935,0.00018766677,0.00027916103,0.00030550384,0.00014213701,0.000022645241,0.00024542643,0.00012764147,0.00016424528],"category_scores_gemma":[0.00026982697,0.00019806671,0.00005481103,0.0008553077,0.00029557192,0.00037731376,0.000065850705,0.0003092984,0.000014633915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011307982,0.00020528029,0.014349378,0.00006177707,0.000007666067,0.0001754475,0.00013529361,0.003310748,0.9801711,0.000044695615,0.000013486765,0.00039435178],"study_design_scores_gemma":[0.001546512,0.0005427351,0.033864148,0.000023563116,0.000033574503,0.00003651122,0.000043120643,0.0050028544,0.95870805,0.000025650588,0.000035910278,0.0001373915],"about_ca_topic_score_codex":0.000013732415,"about_ca_topic_score_gemma":0.000044291464,"teacher_disagreement_score":0.02146305,"about_ca_system_score_codex":0.00007463695,"about_ca_system_score_gemma":0.00008084731,"threshold_uncertainty_score":0.80769265},"labels":[],"label_agreement":null},{"id":"W4405993801","doi":"10.1016/s0026-895x(24)23106-0","title":"Duplications and Defects in the CYP2A6 Gene: Identification, Genotyping, and In Vivo Effects on Smoking","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Genotyping; CYP2A6; Identification (biology); Genetics; Gene; In vivo; Biology; Computational biology; Genotype; In vitro","score_opus":0.029895145519548284,"score_gpt":0.38029568406195907,"score_spread":0.35040053854241077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405993801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98820764,0.0061829705,0.00004250953,0.0020342583,0.00043603094,0.00095893076,0.000019093291,0.00003405111,0.0020845348],"genre_scores_gemma":[0.98029417,0.0032961671,0.000050581177,0.015627237,0.00015108223,0.00041529068,0.000010625369,0.000029740022,0.000125118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970927,0.0012787476,0.00040572273,0.00054949615,0.00014942313,0.0005239012],"domain_scores_gemma":[0.9989592,0.00053024874,0.000092036666,0.000225821,0.000033950968,0.00015873369],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010932141,0.0002733244,0.00027811815,0.00027702661,0.00022785904,0.000037702706,0.0003370345,0.00025047275,0.00051529997],"category_scores_gemma":[0.00004178629,0.00025134746,0.000051921474,0.00044845135,0.00020547773,0.00006598362,0.000066771645,0.0007950194,0.00004034273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020522276,0.00033590407,0.0091931205,0.000051249135,0.000084683576,0.00025887266,0.0012055042,0.0017716874,0.9481289,0.00087689044,0.0012122911,0.036675673],"study_design_scores_gemma":[0.004856976,0.000086220796,0.07626667,0.000014507068,0.0003142448,0.000109825785,0.000038911603,0.0036632216,0.78599876,0.0016326018,0.12658122,0.00043683313],"about_ca_topic_score_codex":0.000024450344,"about_ca_topic_score_gemma":0.000018596751,"teacher_disagreement_score":0.16213013,"about_ca_system_score_codex":0.000042825428,"about_ca_system_score_gemma":0.000044261804,"threshold_uncertainty_score":0.99999386},"labels":[],"label_agreement":null},{"id":"W4408059798","doi":"10.1016/j.molpha.2025.100027","title":"Enhancing remyelination in multiple sclerosis via M1 muscarinic acetylcholine receptor","year":2025,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Alzheimer Society of B.C.; Alzheimer Society; Canadian Institutes of Health Research; University of British Columbia; Michael Smith Health Research BC; Djavad Mowafaghian Centre for Brain Health","keywords":"Remyelination; Muscarinic acetylcholine receptor; Multiple sclerosis; Neuroscience; Acetylcholine; Muscarinic acetylcholine receptor M2; Muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M3; Muscarinic acetylcholine receptor M1; Acetylcholine receptor; Receptor; Medicine; Biology; Pharmacology; Internal medicine; Immunology; Central nervous system; Myelin","score_opus":0.08253456117184231,"score_gpt":0.35251773506359696,"score_spread":0.26998317389175464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408059798","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031374765,0.987318,0.001806358,0.0001669705,0.0049088392,0.0020678886,0.000041403848,0.0002734395,0.00027964485],"genre_scores_gemma":[0.004276481,0.9934047,0.00013723178,0.0012465249,0.00013381067,0.0003903065,0.000017898023,0.000070412614,0.00032266162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963149,0.00065913936,0.00082792545,0.0012066928,0.0002925441,0.0006987938],"domain_scores_gemma":[0.9984538,0.0007706024,0.0002631928,0.0003569957,0.000029131212,0.00012628717],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034533098,0.00052727945,0.0011612651,0.0008852812,0.000123242,0.000042941534,0.00082389184,0.00033648938,0.000093780916],"category_scores_gemma":[0.00083874876,0.00053076464,0.0003701074,0.0019253701,0.00010580177,0.00017553903,0.00038645545,0.0010036922,0.00014004699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000059782033,0.00006363288,2.2617922e-7,0.0020818512,0.000005541095,0.00009311933,0.000012044414,0.000075394695,0.7432926,0.000017253915,0.00008761448,0.2542647],"study_design_scores_gemma":[0.0005625684,0.00005106526,9.0849636e-7,0.0023441412,0.00014745713,0.0000319002,0.0000010924457,0.0007580167,0.5943256,0.0000073304795,0.40131015,0.00045979224],"about_ca_topic_score_codex":0.000008782556,"about_ca_topic_score_gemma":0.000005461993,"teacher_disagreement_score":0.40122253,"about_ca_system_score_codex":0.00024766012,"about_ca_system_score_gemma":0.00020913284,"threshold_uncertainty_score":0.9997144},"labels":[],"label_agreement":null},{"id":"W4409533998","doi":"10.1016/j.molpha.2025.100039","title":"Fat traffic control: S-acylation in axonal transport","year":2025,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Guelph","keywords":"Acylation; Axoplasmic transport; Chemistry; Neuroscience; Biochemistry; Biology","score_opus":0.012669675753188192,"score_gpt":0.303998219396215,"score_spread":0.29132854364302685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409533998","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017640778,0.98488563,0.010668618,0.00004179053,0.0006728304,0.0012465185,0.00010283441,0.000028447768,0.0005892452],"genre_scores_gemma":[0.009848497,0.9751718,0.000060000086,0.00034739127,0.00026127713,0.00032348817,0.013525242,0.00006347105,0.00039880176],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99755806,0.00032358713,0.0007266885,0.00077891565,0.00016173144,0.00045104374],"domain_scores_gemma":[0.9993433,0.000026433336,0.0001846431,0.00029444855,0.00005236104,0.0000988602],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024223616,0.0005167209,0.0011363822,0.0003185827,0.000046358648,0.000009204862,0.00034905138,0.0008447383,0.00014879108],"category_scores_gemma":[0.000010546405,0.00053687586,0.00070578716,0.0003201937,0.00008922396,0.0000035438186,0.000028337428,0.00043279002,0.000017924023],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005349374,0.00074645516,0.000093946706,0.019156933,0.001583078,0.0013376473,0.00005625684,0.0024237023,0.1635021,0.00018413586,0.0009044808,0.8094763],"study_design_scores_gemma":[0.0015463597,0.00010616996,0.000014116462,0.00061078824,0.0010061343,0.000025321897,0.0000021463866,0.00005401637,0.00096797105,0.000006402356,0.99518627,0.00047430734],"about_ca_topic_score_codex":0.0000067483884,"about_ca_topic_score_gemma":0.000040606265,"teacher_disagreement_score":0.99428177,"about_ca_system_score_codex":0.000059440066,"about_ca_system_score_gemma":0.00038909636,"threshold_uncertainty_score":0.9997083},"labels":[],"label_agreement":null},{"id":"W4409687583","doi":"10.1016/j.molpha.2025.100040","title":"Extracellular ATP increases agonist potency and reduces latency at class B G protein-coupled receptors","year":2025,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Agonist; Extracellular; Receptor; Chemistry; Potency; G protein-coupled receptor; Latency (audio); Cell biology; Pharmacology; Biochemistry; Biophysics; Biology; Computer science; In vitro","score_opus":0.005718394237770888,"score_gpt":0.2506404597319988,"score_spread":0.2449220654942279,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409687583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98201764,0.012882632,0.0019902699,0.00084168196,0.0005883683,0.00062417163,0.000009726124,0.000043429096,0.0010020694],"genre_scores_gemma":[0.9889539,0.0005287451,0.0010882606,0.00074136467,0.00015302059,0.00016192783,0.00011900493,0.00004312826,0.008210651],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980796,0.00021935617,0.00036208102,0.0007212839,0.00014424347,0.00047343018],"domain_scores_gemma":[0.99931633,0.000017301258,0.000129483,0.00026542798,0.00011195215,0.00015947646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028136195,0.00032142803,0.00030506903,0.00011514226,0.00027961397,0.000039434337,0.00027535463,0.00032559235,0.00061561464],"category_scores_gemma":[0.00006209249,0.0003237293,0.00014338242,0.00017507515,0.00018602694,0.0000068609897,0.00035133885,0.00018516253,0.000017308457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021028184,0.000114481314,0.00007207659,0.000043651824,0.00018783676,0.00006305792,0.000026616208,0.000046519435,0.9946202,0.0010091889,0.0017719185,0.00183419],"study_design_scores_gemma":[0.00098333,0.00023394382,0.000030278165,0.000022204613,0.00010070686,0.00002504685,0.00003566804,0.0002585268,0.89560527,0.00023201812,0.10217869,0.00029434357],"about_ca_topic_score_codex":0.00007264259,"about_ca_topic_score_gemma":0.0000072570947,"teacher_disagreement_score":0.10040677,"about_ca_system_score_codex":0.000047987585,"about_ca_system_score_gemma":0.0001378414,"threshold_uncertainty_score":0.9999215},"labels":[],"label_agreement":null},{"id":"W4413801696","doi":"10.1016/j.molpha.2025.100073","title":"Differential RELA and GR recruitment to the BIRC3/BIRC2 locus: Molecular insight as to combinatorial regulation by proinflammatory cytokines and glucocorticoid","year":2025,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Glucocorticoid; Locus (genetics); Differential (mechanical device); Biology; Immunology; Computational biology; Genetics; Gene; Physics","score_opus":0.007523388000327163,"score_gpt":0.2754085680994115,"score_spread":0.26788518009908435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413801696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836798,0.0015959719,0.007636938,0.003190882,0.0011870605,0.002265594,0.000017595647,0.00003974571,0.00038645128],"genre_scores_gemma":[0.9940648,0.00008035408,0.0001703674,0.0045173657,0.00015670843,0.00050114014,0.00007069797,0.000050180446,0.00038837822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99795705,0.0003216312,0.00035742452,0.0007550045,0.00021383462,0.00039507993],"domain_scores_gemma":[0.9991464,0.00003053674,0.00009632269,0.0004111588,0.00012268535,0.00019292037],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020665953,0.00032140606,0.00028669828,0.00013775637,0.00014808959,0.000061019975,0.00027542867,0.00023875169,0.000029170158],"category_scores_gemma":[0.00009451352,0.00028818063,0.000075269585,0.0002360721,0.00011676497,0.000006526822,0.00051275943,0.0001841351,0.000023949258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004081273,0.000087033615,0.00015346613,0.00004225116,0.00019484617,0.000034823795,0.000101886806,0.00017126971,0.9877677,0.0017918763,0.007567,0.0016797327],"study_design_scores_gemma":[0.0016805818,0.0005377845,0.0002499238,0.000021674094,0.00013082598,0.000019576517,0.000016349719,0.000075769436,0.8676844,0.0004123874,0.1289042,0.00026650235],"about_ca_topic_score_codex":0.000020222205,"about_ca_topic_score_gemma":0.000006119862,"teacher_disagreement_score":0.12133719,"about_ca_system_score_codex":0.00005005381,"about_ca_system_score_gemma":0.00012870635,"threshold_uncertainty_score":0.999957},"labels":[],"label_agreement":null},{"id":"W4415799958","doi":"10.1016/j.molpha.2025.100076","title":"Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and IKs by UCL2077","year":2025,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Repolarization; Electrophysiology; Context (archaeology); Long QT syndrome; hERG; Potassium channel; Cardiac action potential; Cardiac electrophysiology; Protein subunit","score_opus":0.0030009201398712546,"score_gpt":0.24825501499493352,"score_spread":0.24525409485506228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415799958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99751717,0.00030899205,0.00062745245,0.00091705483,0.000133753,0.0003316617,0.000017522882,0.000012440638,0.00013395741],"genre_scores_gemma":[0.9977671,0.00022110819,0.000013647918,0.0017218535,0.00002068784,0.000021526455,0.000039993174,0.000006293229,0.0001877748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992234,0.0001755687,0.00020443111,0.00017441019,0.00007485753,0.0001473339],"domain_scores_gemma":[0.9996641,0.000027917467,0.00010209817,0.000108113585,0.00007196707,0.00002575971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006774437,0.00009240338,0.0002721277,0.000054323504,0.00003504973,0.0000013397707,0.00003909565,0.00009469371,0.00004948351],"category_scores_gemma":[0.000017961842,0.000067381734,0.000084807216,0.00016592183,0.00018982623,0.000016564336,0.000064741376,0.00018528862,0.0000013899017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051777984,0.00010295781,0.00015337934,0.00005756394,0.00012409677,0.00002131462,0.000019343834,0.000013468164,0.99751145,0.00023303629,0.00028901224,0.00095659355],"study_design_scores_gemma":[0.0010284286,0.00035528198,0.013091833,0.00001753372,0.00014428701,0.000021756141,0.0000025950144,0.00007619055,0.9845653,0.00044748004,0.00020260614,0.000046680612],"about_ca_topic_score_codex":0.0000052111363,"about_ca_topic_score_gemma":1.6206833e-7,"teacher_disagreement_score":0.012946127,"about_ca_system_score_codex":0.000022569631,"about_ca_system_score_gemma":0.00006169813,"threshold_uncertainty_score":0.27477476},"labels":[],"label_agreement":null},{"id":"W4416777107","doi":"10.1016/j.molpha.2025.100094","title":"Amiodarone irrecoverably impairs the function of human ether-a-go-go-related gene potassium channels","year":2025,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"hERG; Amiodarone; Patch clamp; Potassium channel; Efflux; Electrophysiology; In vitro; Drug","score_opus":0.006870983186066172,"score_gpt":0.284524135099406,"score_spread":0.27765315191333984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416777107","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98599046,0.0019693421,0.00091166934,0.0042435247,0.0017671578,0.00060892437,0.0000070986603,0.00007377317,0.0044280505],"genre_scores_gemma":[0.99197274,0.00007243977,0.000034044555,0.004977221,0.00018951466,0.00007412136,0.00006189771,0.000023511693,0.002594519],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984533,0.0003680623,0.00035303805,0.000330216,0.00012542815,0.00036993995],"domain_scores_gemma":[0.9993097,0.0000809285,0.0001319594,0.00029443193,0.00011844343,0.00006451796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002887591,0.00020296882,0.00045994975,0.0001685242,0.0001643975,0.000005046368,0.0001193342,0.000244335,0.0004381696],"category_scores_gemma":[0.000020488582,0.00015846171,0.0002944188,0.0003971751,0.0002543145,0.00002922205,0.00008084795,0.0005455854,0.000059268245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054277125,0.00015136758,0.00010429806,0.00004431253,0.0012615897,0.00020984412,0.000075506156,0.00066617585,0.98571646,0.0011285173,0.008561004,0.0015381286],"study_design_scores_gemma":[0.0040908437,0.0011772249,0.0067320424,0.000030196556,0.0016523196,0.00014627866,0.000032511085,0.00041931262,0.97778606,0.0027785986,0.00496282,0.00019176661],"about_ca_topic_score_codex":0.000021235413,"about_ca_topic_score_gemma":0.0000012739799,"teacher_disagreement_score":0.0079304,"about_ca_system_score_codex":0.00007960092,"about_ca_system_score_gemma":0.00014191217,"threshold_uncertainty_score":0.64618814},"labels":[],"label_agreement":null},{"id":"W4417214314","doi":"10.1016/j.molpha.2025.100097","title":"Mechanism-based inactivation of human aldehyde oxidase by erlotinib: Mechanistic insights from structural analogs and molecular docking","year":2025,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Medical Research Council; Medical Research Council; Bristol-Myers Squibb; Ministry of Education - Singapore; Natural Sciences and Engineering Research Council of Canada; Ministry of Health -Singapore; Swansea University","keywords":"Erlotinib; Potency; Aldehyde oxidase; Cytosol; Docking (animal); Mutagenesis; Structure–activity relationship","score_opus":0.02148160250747714,"score_gpt":0.3700825503373401,"score_spread":0.34860094782986295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417214314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9763732,0.000805663,0.020585634,0.0009532378,0.00023068058,0.0007788091,0.000017228329,0.00006722705,0.0001883196],"genre_scores_gemma":[0.9905095,0.0000121694375,0.00057437463,0.008613834,0.00002143164,0.0000528114,0.00017727212,0.00002345136,0.000015132086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852186,0.00027453274,0.00036678798,0.0003965746,0.00019210561,0.00024813256],"domain_scores_gemma":[0.99922454,0.00012315549,0.00017518882,0.00019137781,0.00013063912,0.00015508426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110657675,0.00021409497,0.00043933626,0.0002970504,0.00013118722,0.00001058677,0.00009110053,0.0001793312,0.00016734366],"category_scores_gemma":[0.000059558686,0.0002147885,0.0000732568,0.000246352,0.00009923793,0.00003906124,0.000057671325,0.00028536574,0.0000032745004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021376595,0.00007738595,0.00018099074,0.00022833206,0.00016500612,0.00014301523,0.000059044196,0.00002071264,0.98542935,0.012825637,0.00022879882,0.00042797846],"study_design_scores_gemma":[0.0045762327,0.0003277556,0.0016927569,0.0000961057,0.00044297875,0.0000048843694,0.000022517777,0.007368375,0.9794265,0.005684328,0.00020500906,0.00015252447],"about_ca_topic_score_codex":0.00016744538,"about_ca_topic_score_gemma":0.000007343114,"teacher_disagreement_score":0.020011257,"about_ca_system_score_codex":0.00010921357,"about_ca_system_score_gemma":0.00014485858,"threshold_uncertainty_score":0.8758821},"labels":[],"label_agreement":null},{"id":"W7476881","doi":"","title":"Through the Eyes of Children: First Nations Children's Perceptions of Health","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Indigenous Health, Education, and Rights","field":"Social Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Perception; Psychology; Optometry; Medicine","score_opus":0.008977633547702774,"score_gpt":0.33334838635819547,"score_spread":0.3243707528104927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7476881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9394609,0.0005906408,0.0021471155,0.0104234405,0.0006964741,0.0010403403,0.000025550804,0.000036120036,0.045579452],"genre_scores_gemma":[0.9952867,0.0031844156,0.00027536854,0.00059557584,0.00025546935,0.000009030125,0.00002602679,0.000009857169,0.00035754748],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980643,0.00091341697,0.00032634105,0.00016193291,0.00021277936,0.00032124334],"domain_scores_gemma":[0.99919564,0.00019337793,0.00025188853,0.0001548142,0.00015038862,0.000053906333],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0007526506,0.00008540924,0.00019309296,0.000087971064,0.004298504,0.0000069604557,0.00031754898,0.00008031055,0.00042557946],"category_scores_gemma":[0.000013883485,0.00006474974,0.000087813605,0.0003561613,0.0006036095,0.000060869224,0.0000028276995,0.00012560425,0.000017139651],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000802696,0.0006699274,0.006861493,0.000056721437,0.00015538605,2.0450116e-7,0.36813226,0.00032958123,0.00037522046,0.62022084,0.0025504404,0.000639896],"study_design_scores_gemma":[0.0018507584,0.00065502216,0.12185521,0.00006379541,0.00027936365,0.000016024062,0.0066901767,0.000043966866,0.011505501,0.0067912177,0.84970134,0.0005476455],"about_ca_topic_score_codex":0.060499158,"about_ca_topic_score_gemma":0.15596806,"teacher_disagreement_score":0.84715086,"about_ca_system_score_codex":0.00007158122,"about_ca_system_score_gemma":0.0027612445,"threshold_uncertainty_score":0.9969978},"labels":[],"label_agreement":null}]}