{"meta":{"query_hash":"9ac964437fc2","filters":{"venue":"Molecular Therapy — Nucleic Acids"},"cohort_total":150,"direct_labels_cover":0,"predictions_cover":150,"exported":150,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/9ac964437fc2","api":"https://metacan.xera.ac/api/v1/cohort?venue=Molecular+Therapy+%E2%80%94+Nucleic+Acids"},"results":[{"id":"W1843766852","doi":"10.1038/mtna.2015.29","title":"Reducing IRF-1 to Levels Observed in HESN Subjects Limits HIV Replication, But Not the Extent of Host Immune Activation","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Transactivation; Biology; Gene knockdown; Ex vivo; Immune system; Virology; Flow cytometry; Viral replication; Reverse transcriptase; Immunology; Gene; Gene expression; Polymerase chain reaction; In vivo; Virus; Genetics","score_opus":0.05886342397346205,"score_gpt":0.28887208716146734,"score_spread":0.23000866318800528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1843766852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923132,0.0016080523,0.0006204003,0.004233438,0.00008841452,0.0007786215,0.000030694344,0.00003508875,0.00029206087],"genre_scores_gemma":[0.99825454,0.00008212356,0.00023622303,0.0004138252,0.000012732827,0.00013248863,0.00010995686,0.000028729442,0.00072937174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838537,0.00037614524,0.00035711494,0.0003953515,0.00011829649,0.00036772754],"domain_scores_gemma":[0.9985969,0.00007572443,0.000118975746,0.0009729465,0.00018139463,0.000054046315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064427557,0.00018401173,0.0002623084,0.00012656298,0.000105276886,0.000018969751,0.00038672352,0.00014251492,0.000081592654],"category_scores_gemma":[0.0002542288,0.0001335009,0.00009391398,0.00034362648,0.000110031324,0.00007697623,0.00007387771,0.00021949942,0.00031637982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006014299,0.0002411956,0.0011447209,0.0000047612634,0.00014853662,0.000008361665,0.0018023552,0.000049647362,0.9836164,0.00022019826,0.00024834726,0.011914055],"study_design_scores_gemma":[0.0021374747,0.00048206744,0.08384048,0.000040408377,0.0000073931765,0.000010244961,0.0002986413,0.000005301753,0.90857214,0.00008844297,0.004388739,0.00012864813],"about_ca_topic_score_codex":0.0005199244,"about_ca_topic_score_gemma":0.000013716115,"teacher_disagreement_score":0.08269576,"about_ca_system_score_codex":0.00013755729,"about_ca_system_score_gemma":0.00013454007,"threshold_uncertainty_score":0.5444009},"labels":[],"label_agreement":null},{"id":"W1966445473","doi":"10.1038/mtna.2012.55","title":"Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Zinc finger nuclease; Integrase; Myogenesis; Genetic enhancement; Biology; Insertional mutagenesis; Transplantation; Gene targeting; Molecular biology; Cell biology; Gene; Cancer research; Myocyte; Genome editing; Genetics; CRISPR; Genome; Medicine","score_opus":0.003712537081160202,"score_gpt":0.23236892091297723,"score_spread":0.22865638383181702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966445473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96760976,0.0007897348,0.031088274,0.000040676023,0.000056816727,0.0002857669,0.000025573541,0.000015450127,0.00008795405],"genre_scores_gemma":[0.9967685,0.00022577363,0.0022812858,0.00010657221,0.00005795157,0.000041763367,0.0004454645,0.00004205593,0.000030669733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902827,0.00005185457,0.00027814845,0.00028787006,0.00012258261,0.00023130166],"domain_scores_gemma":[0.999584,0.0000035799414,0.000064585394,0.00023559462,0.000057880137,0.000054339573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007548301,0.00018184767,0.00015893127,0.0000841217,0.00003528297,0.000014147983,0.00016303179,0.00014704921,0.0001427777],"category_scores_gemma":[0.0000046779555,0.00019414755,0.00010891461,0.0001198964,0.000051487063,0.0000075889207,0.000019907238,0.000089388006,0.000013560731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021879538,0.000071544266,0.00015179723,0.000021157832,0.000035239384,0.0000067718447,0.00011187913,0.0006382317,0.9934427,0.000008203769,0.00005299955,0.0054375846],"study_design_scores_gemma":[0.0010569944,0.0002722744,0.03096676,0.000014160712,0.000008830838,0.0000126115965,0.000027804206,0.00019595344,0.9664128,0.000060879047,0.00076671835,0.0002042389],"about_ca_topic_score_codex":0.0001246366,"about_ca_topic_score_gemma":0.000020237283,"teacher_disagreement_score":0.030814964,"about_ca_system_score_codex":0.000013230703,"about_ca_system_score_gemma":0.000013276362,"threshold_uncertainty_score":0.79171073},"labels":[],"label_agreement":null},{"id":"W1966858164","doi":"10.1038/mtna.2013.48","title":"Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Small hairpin RNA; In vivo; Genetic enhancement; RNA interference; Viral vector; Integrase; Lentivirus; Virology; Biology; RNA; Medicine; Computational biology; Cancer research; Human immunodeficiency virus (HIV); Gene; Recombinant DNA; Genetics","score_opus":0.03226083350734438,"score_gpt":0.2955138434189087,"score_spread":0.2632530099115643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966858164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948767,0.0020805646,0.001575116,0.00022990923,0.000107989945,0.00082272437,0.00002596422,0.0000061962705,0.00027488012],"genre_scores_gemma":[0.9972719,0.00068730937,0.0008002614,0.0009961367,0.000033594697,0.00008029164,0.00003561019,0.000031508487,0.00006337695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980892,0.00043557573,0.0005188494,0.00035162107,0.00038427,0.00022050773],"domain_scores_gemma":[0.99859434,0.000018294748,0.00022551301,0.0007587846,0.00035655047,0.00004653328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063627807,0.00020477283,0.0002514445,0.000060476505,0.000036650392,0.000012238913,0.00049415627,0.0002254196,0.00019380302],"category_scores_gemma":[0.00008319751,0.00015087103,0.0002776518,0.00016411142,0.00016877691,0.000007276434,0.000070574635,0.00012210938,0.000009703647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026610377,0.0002907205,0.010107915,0.000005350632,0.00009113848,5.5520024e-7,0.00008497955,0.002204181,0.96567255,0.000003849052,0.00012271396,0.021149937],"study_design_scores_gemma":[0.0036063623,0.00034219876,0.030038627,0.000034492055,0.000013081908,9.4989593e-7,0.000039436443,0.005510784,0.9591818,0.000048041995,0.0010166647,0.0001675899],"about_ca_topic_score_codex":0.000053655374,"about_ca_topic_score_gemma":0.000015286343,"teacher_disagreement_score":0.020982347,"about_ca_system_score_codex":0.000024190007,"about_ca_system_score_gemma":0.00017583322,"threshold_uncertainty_score":0.6152342},"labels":[],"label_agreement":null},{"id":"W1971858687","doi":"10.1038/mtna.2012.35","title":"Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids","year":2012,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Gene silencing; LNCaP; Oligonucleotide; Locked nucleic acid; Nucleic acid; Molecular biology; Biology; Phosphodiester bond; Biochemistry; Chemistry; RNA; DNA; Gene; Cancer cell; Cancer; Genetics","score_opus":0.008719407089710725,"score_gpt":0.23814163292663845,"score_spread":0.22942222583692773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971858687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9847167,0.008337874,0.0052285353,0.0001367704,0.00033426893,0.0005116076,0.0001275749,0.000043497457,0.0005631748],"genre_scores_gemma":[0.992382,0.0023572736,0.0030708008,0.0014215254,0.00014398666,0.000053233583,0.00022676468,0.00013055366,0.00021385311],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99652994,0.0002863519,0.0007645463,0.00089272193,0.00050440384,0.0010220353],"domain_scores_gemma":[0.99794614,0.000016448264,0.00032460244,0.0012242264,0.00018052023,0.00030803305],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038008692,0.00064126425,0.00065429637,0.00020370299,0.00012571062,0.000050358325,0.0007753645,0.00054148264,0.00022240556],"category_scores_gemma":[0.000052492607,0.0006216566,0.00043333005,0.00036817824,0.00028748743,0.00006275853,0.00020217044,0.00031842614,0.000081779646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007593474,0.00042272505,0.0021413849,0.000031914853,0.00014666645,0.000013823797,0.00074648584,0.000029120278,0.9837274,0.0000049139517,0.0008638868,0.011112334],"study_design_scores_gemma":[0.0017280342,0.0005878951,0.0017740537,0.00007876434,0.000036251335,0.000016560545,0.00032534805,0.000055473804,0.9925859,0.00004350259,0.0020822147,0.00068601227],"about_ca_topic_score_codex":0.00006981707,"about_ca_topic_score_gemma":0.0000024513865,"teacher_disagreement_score":0.010426322,"about_ca_system_score_codex":0.00006960044,"about_ca_system_score_gemma":0.000092986345,"threshold_uncertainty_score":0.9996235},"labels":[],"label_agreement":null},{"id":"W1973717479","doi":"10.1038/mtna.2013.41","title":"A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Frataxin; Haploinsufficiency; Ataxia; Biology; Transcription (linguistics); MyoD; Molecular biology; Gene expression; Cancer research; Gene; Cell biology; Genetics; Iron-binding proteins; Phenotype","score_opus":0.021281509997556586,"score_gpt":0.23969595895994047,"score_spread":0.21841444896238388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973717479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7473174,0.00023639247,0.24981529,0.00014594592,0.00006670381,0.0022043071,0.000020787416,0.00006472118,0.00012851779],"genre_scores_gemma":[0.9814809,0.00002944046,0.01669879,0.0007026097,0.00008593842,0.0005813059,0.000020607611,0.000095646,0.00030473992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978208,0.0002354735,0.00029492524,0.0007437005,0.00051343703,0.0003916496],"domain_scores_gemma":[0.99881184,0.000025270927,0.00020908576,0.00065880327,0.00012865668,0.00016632701],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007120012,0.0003302612,0.00028868893,0.00011428621,0.0001775317,0.00009571392,0.00045771326,0.00012087498,0.00018539873],"category_scores_gemma":[0.00004808351,0.0002534166,0.00014784203,0.00033567406,0.00020170877,0.00024234662,0.00006473923,0.00016324257,0.000017686556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000320054,0.00032130303,0.00014146714,0.000023545701,0.000023079518,0.0000034599836,0.00016807894,0.00067630486,0.9909614,0.0001733197,0.00017682038,0.0070112203],"study_design_scores_gemma":[0.001833306,0.0008421699,0.001282036,0.000017979144,0.00002239208,0.0000149775115,0.000098634046,0.0009802998,0.99340165,0.0008498548,0.00036939577,0.00028728636],"about_ca_topic_score_codex":0.000046959743,"about_ca_topic_score_gemma":4.0487174e-7,"teacher_disagreement_score":0.23416358,"about_ca_system_score_codex":0.000021045145,"about_ca_system_score_gemma":0.00011533523,"threshold_uncertainty_score":0.99999183},"labels":[],"label_agreement":null},{"id":"W1975230816","doi":"10.1038/mtna.2013.55","title":"Efficient Gene Delivery to Pig Airway Epithelia and Submucosal Glands Using Helper-Dependent Adenoviral Vectors","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Energy Harvesting in Wireless Networks","field":"Engineering","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"University of Toronto","keywords":"Transgene; Genetic enhancement; Gene delivery; Cystic fibrosis; Reporter gene; Biology; Lung; Cystic fibrosis transmembrane conductance regulator; Viral vector; Vector (molecular biology); Airway; Gene; Cell biology; Pathology; Medicine; Gene expression; Internal medicine; Recombinant DNA; Genetics","score_opus":0.007648908038756065,"score_gpt":0.1933627085369163,"score_spread":0.18571380049816025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975230816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97175413,0.0023151524,0.024416965,0.00005803197,0.00049331243,0.00035369178,0.0000072791677,0.000419897,0.00018153268],"genre_scores_gemma":[0.99239194,0.00012848241,0.0066404077,0.00035829566,0.00018836408,0.00004638604,0.000009622583,0.00018586918,0.000050622515],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99811864,0.00008356864,0.00033503765,0.0004459611,0.00036851506,0.0006482707],"domain_scores_gemma":[0.9990708,0.000036748723,0.00004492175,0.0004812794,0.00007471256,0.00029148895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017307374,0.00041586556,0.00033004512,0.00017162316,0.00013885235,0.00015941409,0.0003191604,0.00020694286,0.00010851491],"category_scores_gemma":[0.000013772865,0.00040955303,0.000099488454,0.00030035488,0.000070194365,0.0000804328,0.000116949355,0.00028334072,0.00009357992],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016440412,0.000027405706,0.0012604435,0.000011744104,0.0000793549,0.000036852034,0.00026399692,0.48413265,0.5046732,0.000033919452,0.000046849203,0.009417155],"study_design_scores_gemma":[0.0019333897,0.0003682691,0.017544286,0.00015092114,0.000051180585,0.00011247272,0.00009234464,0.6565474,0.32038522,0.000069667694,0.0012813584,0.0014634865],"about_ca_topic_score_codex":0.00019074907,"about_ca_topic_score_gemma":0.000008698298,"teacher_disagreement_score":0.18428797,"about_ca_system_score_codex":0.00015440388,"about_ca_system_score_gemma":0.000021266009,"threshold_uncertainty_score":0.9998356},"labels":[],"label_agreement":null},{"id":"W2016613547","doi":"10.1038/mtna.2014.2","title":"R88-APOBEC3Gm Inhibits the Replication of Both Drug-resistant Strains of HIV-1 and Viruses Produced From Latently Infected Cells","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"","keywords":"Virology; Biology; Viral replication; Cell culture; Viral vector; Virus; Antiviral drug; Vector (molecular biology); Drug resistance; Gene; Microbiology; Genetics","score_opus":0.012088274056981452,"score_gpt":0.2402584025263833,"score_spread":0.22817012846940185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016613547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966172,0.0018770883,0.00018222578,0.0003583889,0.000039996125,0.00048160512,0.00017618133,0.00003139272,0.00023594902],"genre_scores_gemma":[0.99914473,0.00024866246,0.00012199586,0.00013502694,0.00000916662,0.000025312347,0.0001483856,0.00002214239,0.00014457657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867076,0.00038541597,0.00028198955,0.0003572436,0.00007881408,0.00022579792],"domain_scores_gemma":[0.9988823,0.00008419981,0.00016354879,0.00075603975,0.00008566816,0.000028279397],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029904247,0.00016316312,0.0002661713,0.00006405756,0.00009927379,0.000011868314,0.00020691626,0.00010604025,0.0001345081],"category_scores_gemma":[0.000059394333,0.00010884434,0.000082960774,0.00013351708,0.00031239275,0.00003751875,0.000060141385,0.00014281682,0.00006502831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026575773,0.00022001872,0.0028369913,0.000010709464,0.00033724323,0.0000015661964,0.00065011316,0.0000029128328,0.9861303,0.00034308163,0.00021202976,0.008989308],"study_design_scores_gemma":[0.0018294854,0.0003435262,0.033939652,0.00002487321,0.00003243266,0.00000172335,0.00004752304,0.0000043659193,0.9565857,0.00021458356,0.0068785218,0.00009763428],"about_ca_topic_score_codex":0.00035513684,"about_ca_topic_score_gemma":0.000024906672,"teacher_disagreement_score":0.03110266,"about_ca_system_score_codex":0.000016741184,"about_ca_system_score_gemma":0.00004189975,"threshold_uncertainty_score":0.44385433},"labels":[],"label_agreement":null},{"id":"W2064585559","doi":"10.1038/mtna.2014.16","title":"DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Plasmid; Biology; DNA; Transfection; Gene; In vitro recombination; Gene delivery; Molecular biology; Cell biology; Genetics; Gene expression; Molecular cloning","score_opus":0.006408798544861105,"score_gpt":0.24153813930062534,"score_spread":0.23512934075576425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064585559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99450177,0.00266844,0.0012112784,0.00020502498,0.00012051872,0.00053958443,0.000016031232,0.000045780842,0.0006915706],"genre_scores_gemma":[0.9964337,0.0008968495,0.00051204616,0.0014811164,0.0002203922,0.000083488216,0.0000793238,0.00010693099,0.0001862072],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776226,0.00038809728,0.00024682525,0.0007363762,0.00032832808,0.00053808175],"domain_scores_gemma":[0.9987768,0.000037377133,0.0000861787,0.0007547706,0.00011888396,0.00022601274],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047065667,0.00037501781,0.00030013715,0.00010966017,0.0001781083,0.000074488424,0.00040367796,0.000269704,0.000048719998],"category_scores_gemma":[0.000062482686,0.00036158034,0.00017482566,0.00018031031,0.00025266345,0.000007919275,0.00017047835,0.00019468396,0.000051859122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017130501,0.00008646608,0.00058410503,0.000014066329,0.00020953536,0.00001538777,0.00006635171,0.000026869968,0.95193565,0.000044896922,0.00017095623,0.04513268],"study_design_scores_gemma":[0.0020840806,0.004373838,0.0026919467,0.000014030411,0.000015522959,0.00002150224,0.00001684661,0.0000678476,0.9639306,0.00011929523,0.026249288,0.00041519164],"about_ca_topic_score_codex":0.000016414551,"about_ca_topic_score_gemma":0.000010411466,"teacher_disagreement_score":0.04471749,"about_ca_system_score_codex":0.00003682333,"about_ca_system_score_gemma":0.00006163572,"threshold_uncertainty_score":0.9998836},"labels":[],"label_agreement":null},{"id":"W2066045650","doi":"10.1038/mtna.2013.20","title":"Optimization of Ultrasound-mediated Anti-angiogenic Cancer Gene Therapy","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Krembil Foundation; University of Toronto","keywords":"Microbubbles; Gene knockdown; Gene silencing; Cancer research; Angiogenesis; Medicine; Neovascularization; Genetic enhancement; Small hairpin RNA; Perfusion; Ultrasound; Cancer; Pathology; Biology; Internal medicine; Gene; Radiology","score_opus":0.0071330237287042415,"score_gpt":0.2058646890681221,"score_spread":0.19873166533941786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066045650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96027166,0.006130608,0.03192205,0.00012569733,0.00011244071,0.0005228165,0.00003421074,0.00030164362,0.00057886983],"genre_scores_gemma":[0.98537856,0.010085179,0.0036224239,0.00037438388,0.00006067,0.00023105179,0.00009457263,0.00011141152,0.000041729145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989768,0.000032953143,0.00028511413,0.00021917705,0.00019778771,0.0002881282],"domain_scores_gemma":[0.99927676,0.00004435414,0.00005985771,0.00042228666,0.000109133114,0.00008758397],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000056549834,0.00023814678,0.00025458325,0.0000990014,0.000066278386,0.00004516033,0.00028054893,0.00014322334,0.0016624462],"category_scores_gemma":[0.0000069403113,0.0002180448,0.00015371309,0.00039872134,0.00007239488,0.00012910426,0.000009205067,0.000108901535,0.00010273662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004551013,0.00005979609,0.0012329343,0.000006117069,0.00021806285,7.292179e-7,0.00022089637,0.06969946,0.9233265,0.000048146736,0.00024740846,0.0049354164],"study_design_scores_gemma":[0.0021244374,0.00010939441,0.015403024,0.000024631549,0.000041964075,0.000017035507,0.00007835005,0.02682304,0.9383558,0.0003155225,0.015923528,0.0007832577],"about_ca_topic_score_codex":0.00010454068,"about_ca_topic_score_gemma":0.000001376426,"teacher_disagreement_score":0.04287642,"about_ca_system_score_codex":0.00003956659,"about_ca_system_score_gemma":0.000024586327,"threshold_uncertainty_score":0.9992502},"labels":[],"label_agreement":null},{"id":"W2083922607","doi":"10.1038/mtna.2014.76","title":"Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45–55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"National Center for Research Resources; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Medical Research Council","keywords":"Morpholino; Exon skipping; Dystrophin; Duchenne muscular dystrophy; Exon; In vivo; mdx mouse; Muscular dystrophy; Biology; Medicine; Gene knockdown; Genetics; Alternative splicing; Gene","score_opus":0.011977442730804682,"score_gpt":0.24477628319018546,"score_spread":0.2327988404593808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083922607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929308,0.0035987564,0.0026909998,0.000033340977,0.000096525306,0.00046356587,0.000013646292,0.000017360022,0.00015498548],"genre_scores_gemma":[0.9986021,0.00022201308,0.000785161,0.0001479224,0.000054384192,0.00002986906,0.00007863053,0.000054548123,0.000025354524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822956,0.00023815753,0.00048971025,0.00046218353,0.00021529481,0.00036511195],"domain_scores_gemma":[0.99887174,0.000024259061,0.00029505618,0.0005014162,0.00018996632,0.00011757934],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000292473,0.00029354048,0.00044457347,0.00011461059,0.000042097625,0.000009374463,0.00036927586,0.00025970445,0.00001701124],"category_scores_gemma":[0.000104770224,0.00026286996,0.00015135009,0.00021518866,0.00023309968,0.000009668489,0.00009578459,0.00017519933,0.0000051033885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018314779,0.0003689434,0.017348252,0.00008720456,0.0001579106,0.000027659247,0.0005328777,0.0015877262,0.97722924,0.000025959382,0.000055167024,0.00074757676],"study_design_scores_gemma":[0.011269906,0.0014830241,0.016131299,0.0003367385,0.000047255922,0.00004072597,0.0007094654,0.0002263351,0.96901613,0.000037003687,0.00014558462,0.0005565504],"about_ca_topic_score_codex":0.0001068264,"about_ca_topic_score_gemma":0.000016475777,"teacher_disagreement_score":0.009438428,"about_ca_system_score_codex":0.000026222158,"about_ca_system_score_gemma":0.0001420906,"threshold_uncertainty_score":0.99998236},"labels":[],"label_agreement":null},{"id":"W2086596897","doi":"10.1038/mtna.2014.39","title":"Lentivector Integration Sites in Ependymal Cells From a Model of Metachromatic Leukodystrophy: Non-B DNA as a New Factor Influencing Integration","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Francis Crick Institute","keywords":"Metachromatic leukodystrophy; Leukodystrophy; Metachromasia; Biology; Medicine; Genetics; Pathology","score_opus":0.011485408906375331,"score_gpt":0.23916429436255274,"score_spread":0.2276788854561774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086596897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8630211,0.00012453388,0.13629249,0.000064143314,0.00004140738,0.000272028,0.000015337891,0.00001611008,0.00015286711],"genre_scores_gemma":[0.9936059,0.000024232833,0.005572637,0.00045299192,0.00005097255,0.000017645696,0.00016318265,0.00003696652,0.00007548553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868107,0.00013222147,0.0003794651,0.00038541044,0.00022769124,0.00019416034],"domain_scores_gemma":[0.9991567,0.000012464165,0.00018010243,0.00041725664,0.000083927785,0.00014951287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096126656,0.00025302343,0.00026947042,0.00011023159,0.000036416066,0.000048163587,0.00022163884,0.00017105104,0.00007268616],"category_scores_gemma":[0.00008580854,0.00023068966,0.00018710984,0.00012676671,0.000052399446,0.000023282739,0.000056592442,0.00010272949,0.000013878294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022694029,0.0000860411,0.0008419784,0.000007050612,0.000055904235,0.0000015176212,0.00051360525,0.0045556095,0.9873632,0.00015943978,0.000019117388,0.0061696046],"study_design_scores_gemma":[0.0013400182,0.0002446824,0.0071124323,0.000033802393,0.000020966096,5.6816276e-7,0.000096209566,0.097439796,0.89217794,0.0012888695,0.000028498089,0.00021621384],"about_ca_topic_score_codex":0.00026474785,"about_ca_topic_score_gemma":0.000045048808,"teacher_disagreement_score":0.13071986,"about_ca_system_score_codex":0.00003684943,"about_ca_system_score_gemma":0.00015370992,"threshold_uncertainty_score":0.94072515},"labels":[],"label_agreement":null},{"id":"W2086747295","doi":"10.1038/mtna.2013.66","title":"Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":482,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Acuitas Therapeutics (Canada)","funders":"","keywords":"Gene silencing; In vivo; Polyethylene glycol; PEG ratio; PEGylation; Chemistry; Gene knockdown; Pharmacokinetics; Biophysics; Gene delivery; Biodistribution; Lipid metabolism; Pharmacology; Biochemistry; Cell biology; In vitro; Genetic enhancement; Gene; Biology","score_opus":0.00803909908987599,"score_gpt":0.2527792610581531,"score_spread":0.24474016196827714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086747295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99804187,0.0010939715,0.00023397067,0.00012878832,0.00006530913,0.00033442932,0.000017163096,0.000012045686,0.00007247118],"genre_scores_gemma":[0.99579036,0.002968446,0.00032193257,0.0007201079,0.00006427315,0.00003083445,0.000021366704,0.000034326094,0.000048343994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882126,0.00009297535,0.00034765754,0.00031648655,0.00018195924,0.0002396848],"domain_scores_gemma":[0.99918425,0.000015962702,0.00017624644,0.0003255584,0.00020726833,0.00009070481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011062464,0.00022565598,0.00022669301,0.00007441119,0.000039834933,0.000020722822,0.0002497739,0.00013028234,0.00004916804],"category_scores_gemma":[0.000024339703,0.00020742184,0.00009783454,0.00012085897,0.0001982598,0.000015175755,0.000081934624,0.0000960107,0.000013360047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030336468,0.00014701772,0.0021848707,0.000026518812,0.00011818345,0.0000016922785,0.00008677684,0.0014888764,0.9838378,0.00003063621,0.000087355525,0.011686934],"study_design_scores_gemma":[0.0010973194,0.0011417383,0.005836595,0.000034824116,0.00002413312,0.0000061870855,0.000036337024,0.0007615775,0.99006194,0.00007511571,0.0007166041,0.00020761626],"about_ca_topic_score_codex":0.000044437904,"about_ca_topic_score_gemma":0.0000014337038,"teacher_disagreement_score":0.011479318,"about_ca_system_score_codex":0.000008908526,"about_ca_system_score_gemma":0.00003066738,"threshold_uncertainty_score":0.8458417},"labels":[],"label_agreement":null},{"id":"W2089960454","doi":"10.1038/mtna.2013.7","title":"Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined “Complementary Lethality”","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Synthetic lethality; Cancer research; Gene knockdown; DNA repair; Cisplatin; Biology; DNA damage; Thymidylate synthase; Cancer; Downregulation and upregulation; DNA; Chemotherapy; Cell culture; Genetics; Gene","score_opus":0.007455542165294894,"score_gpt":0.219443365211617,"score_spread":0.2119878230463221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089960454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963539,0.00026346438,0.0022101162,0.00024366842,0.00008012875,0.0006849684,0.0000537191,0.000016772909,0.00009322552],"genre_scores_gemma":[0.9976656,0.000103347535,0.0015183698,0.000489968,0.000030783038,0.00003211386,0.000095270094,0.000038014805,0.000026527192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986862,0.0002543786,0.00032824042,0.00033501774,0.0001927514,0.00020339637],"domain_scores_gemma":[0.99909776,0.0000228912,0.0002185934,0.00044380245,0.00015709148,0.000059871458],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002728314,0.00021467199,0.00023592981,0.000051254035,0.000074346935,0.000017898965,0.00012701857,0.000101724545,0.0000691004],"category_scores_gemma":[0.000017564222,0.00017071453,0.00012398408,0.000094504874,0.0002449633,0.000013899998,0.00011692242,0.00010138771,0.000005405933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014962978,0.00012675422,0.00015886207,0.000021542211,0.00017128822,0.0000055883515,0.00030557447,0.000018240546,0.99492633,0.000082805775,0.00005053521,0.0039828476],"study_design_scores_gemma":[0.0011670872,0.0006626812,0.0017031982,0.000024796387,0.00003220496,0.000017959546,0.00046998527,0.00030587605,0.99453986,0.00075340475,0.00014895151,0.00017399353],"about_ca_topic_score_codex":0.0003417465,"about_ca_topic_score_gemma":0.0000052163605,"teacher_disagreement_score":0.0038088541,"about_ca_system_score_codex":0.000013019054,"about_ca_system_score_gemma":0.000019552368,"threshold_uncertainty_score":0.69615364},"labels":[],"label_agreement":null},{"id":"W2103100938","doi":"10.1038/mtna.2014.41","title":"Agonistic CD200R1 DNA Aptamers Are Potent Immunosuppressants That Prolong Allogeneic Skin Graft Survival","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Aptamer; Immunogenicity; Immune system; Immunology; Inflammation; Cancer research; Biology; Cell biology; Molecular biology","score_opus":0.02988824590077677,"score_gpt":0.24169733543899205,"score_spread":0.21180908953821528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103100938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97870016,0.00006799853,0.016254434,0.0011360787,0.0011463753,0.00074942573,0.000019502937,0.0005451429,0.0013808785],"genre_scores_gemma":[0.9936545,0.00018920901,0.000302566,0.0050862036,0.000107887514,0.00007316717,0.000013748109,0.00017386135,0.0003988434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99595034,0.0010052113,0.00045576273,0.0009954761,0.0009354295,0.00065778295],"domain_scores_gemma":[0.99825,0.00011390765,0.00031845528,0.0010196808,0.00006999587,0.00022796965],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004026098,0.00049033336,0.0004173566,0.00020030778,0.00045540647,0.00026880854,0.00079101155,0.00016365544,0.00018723517],"category_scores_gemma":[0.0002332084,0.0004594048,0.00026637377,0.000359386,0.0001888465,0.00021140884,0.00013458691,0.00033184572,0.00033765184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000109471286,0.00012092229,0.00017742859,0.000010927534,0.000015194752,0.000092440925,0.00011911411,0.00054919306,0.9907348,0.0023103047,0.000081416125,0.0056787515],"study_design_scores_gemma":[0.001515227,0.00024898228,0.003364621,0.000015844282,0.000017323046,0.000058882382,0.000036154677,0.0036311918,0.98222804,0.000763356,0.007629272,0.000491104],"about_ca_topic_score_codex":0.000005066808,"about_ca_topic_score_gemma":0.0000032440578,"teacher_disagreement_score":0.015951868,"about_ca_system_score_codex":0.0000415652,"about_ca_system_score_gemma":0.00004038107,"threshold_uncertainty_score":0.9997858},"labels":[],"label_agreement":null},{"id":"W2108528276","doi":"10.1038/mtna.2014.31","title":"A Conserved Target Site in HIV-1 Gag RNA is Accessible to Inhibition by Both an HDV Ribozyme and a Short Hairpin RNA","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Atlantic Cancer Research Institute; McGill University; Jewish General Hospital","funders":"Los Alamos National Laboratory","keywords":"Ribozyme; RNA; Biology; Small hairpin RNA; Ligase ribozyme; Mammalian CPEB3 ribozyme; Hairpin ribozyme; Stem-loop; Virology; Antisense RNA; Computational biology; RNA interference; Gene; Genetics","score_opus":0.011427819779424692,"score_gpt":0.25916361828040513,"score_spread":0.24773579850098043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108528276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99299765,0.0022289227,0.0017989305,0.0014237347,0.00004902558,0.0005430843,0.0001559433,0.00006971358,0.0007330212],"genre_scores_gemma":[0.9954717,0.00021068804,0.0005123682,0.0024365429,0.0000130584685,0.000088637025,0.0006548952,0.000042204407,0.00056986493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981142,0.000434235,0.00026423833,0.00053537905,0.000087620414,0.0005643043],"domain_scores_gemma":[0.99932647,0.000029048691,0.00004254723,0.00042955973,0.000042702497,0.00012965385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033515328,0.000272799,0.0003535988,0.00018258345,0.00016331371,0.00007154765,0.0001913796,0.00023416978,0.0006169385],"category_scores_gemma":[0.000023661545,0.00024173634,0.00007537179,0.00021356255,0.00015618652,0.00015902173,0.00008936949,0.0002686283,0.00054616464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052588835,0.00034356062,0.01090272,0.000008998508,0.00012781066,0.000049743536,0.0009450923,0.000003204035,0.971487,0.00008299186,0.0058546956,0.0096682925],"study_design_scores_gemma":[0.0056001446,0.0015418801,0.013118455,0.000054862812,0.000016193271,0.0000302491,0.00010337221,0.00009211641,0.92233896,0.00030547343,0.05637615,0.0004221661],"about_ca_topic_score_codex":0.00029363413,"about_ca_topic_score_gemma":0.00006748921,"teacher_disagreement_score":0.050521456,"about_ca_system_score_codex":0.000060521634,"about_ca_system_score_gemma":0.000043942287,"threshold_uncertainty_score":0.9857722},"labels":[],"label_agreement":null},{"id":"W2109389041","doi":"10.1038/mtna.2015.11","title":"Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Bill and Carol Fox Center for Humanistic Inquiry, Emory University; University of Missouri","keywords":"Aptamer; Immunogenicity; Immune system; Antibody; In vivo; Monoclonal antibody; Cancer research; PD-L1; Melanoma; Ipilimumab; Immunology; Immunotherapy; Pharmacology; Medicine; Biology; Molecular biology","score_opus":0.02441765053098609,"score_gpt":0.2724354712923907,"score_spread":0.2480178207614046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109389041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8998891,0.09367866,0.0032971539,0.0007854409,0.00039726135,0.0016723833,0.00003249205,0.000070474794,0.00017703565],"genre_scores_gemma":[0.99347013,0.004181625,0.00008843368,0.0003560239,0.000023488574,0.00031719022,0.00007933375,0.000091687776,0.0013921014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980562,0.0003741715,0.00046729876,0.0003912585,0.00013362877,0.00057747844],"domain_scores_gemma":[0.99822336,0.00039748874,0.0003170076,0.00081288826,0.0002177336,0.00003151323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005345226,0.00046058078,0.00050578703,0.00008756235,0.0004853112,0.000044919052,0.0006138315,0.00023821976,0.00015396709],"category_scores_gemma":[0.000036690035,0.00023164325,0.0003163716,0.00032681614,0.0007125185,0.000089466965,0.000028468048,0.00021778888,0.000028259856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010261888,0.0003912965,0.00008173432,0.000007141134,0.0020476924,0.0000038785092,0.004982916,0.0003919281,0.923584,0.0002763485,0.000081222206,0.05788997],"study_design_scores_gemma":[0.008831314,0.0076433825,0.0012952073,0.000058213627,0.00020959566,0.00006748345,0.0070797666,0.00011641882,0.8622688,0.000116639174,0.11190971,0.00040346713],"about_ca_topic_score_codex":0.0006608945,"about_ca_topic_score_gemma":0.000012541432,"teacher_disagreement_score":0.11182848,"about_ca_system_score_codex":0.00019891578,"about_ca_system_score_gemma":0.00034555598,"threshold_uncertainty_score":0.94461375},"labels":[],"label_agreement":null},{"id":"W2116648459","doi":"10.1038/mtna.2013.50","title":"Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in Mice","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Arbutus Biopharma (Canada)","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Internal ribosome entry site; Luciferase; In vivo; Gene expression; Molecular biology; Hepatitis C virus; Gene; Biology; Messenger RNA; Virology; Virus; Transfection; Biochemistry; Translation (biology); Genetics","score_opus":0.007279195911446764,"score_gpt":0.2083072658958608,"score_spread":0.20102806998441403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2116648459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99725246,0.0016010789,0.00034264437,0.00012393486,0.00008240515,0.000474159,0.000016791724,0.000021512235,0.00008498017],"genre_scores_gemma":[0.9968325,0.0013067211,0.0012054003,0.00036233992,0.00006138547,0.00007863046,0.000043058044,0.000060350005,0.000049635833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982835,0.00012951846,0.0004394251,0.00050009385,0.00025516097,0.0003923167],"domain_scores_gemma":[0.9989951,0.000010897221,0.00021249343,0.00050281547,0.00016596515,0.0001127059],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011481126,0.00031144594,0.00032117972,0.00010904008,0.000059182606,0.000037485413,0.00032567873,0.0002275207,0.000076219156],"category_scores_gemma":[0.00002490437,0.00025313877,0.00014267954,0.00017603995,0.00012653985,0.00002071982,0.00010599348,0.00012714526,0.000028698223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003875984,0.00022895793,0.010181501,0.000015567859,0.000084536805,0.000027407375,0.0001527118,0.00020494468,0.98316115,0.0000024253009,0.00014612079,0.0054070484],"study_design_scores_gemma":[0.0012143708,0.0010198237,0.016382618,0.0001412242,0.000015005712,0.000015216702,0.00010503014,0.00022737948,0.98007405,0.000030945463,0.00044896503,0.00032536476],"about_ca_topic_score_codex":0.00041794928,"about_ca_topic_score_gemma":0.00008551158,"teacher_disagreement_score":0.0062011173,"about_ca_system_score_codex":0.000026287087,"about_ca_system_score_gemma":0.000046645808,"threshold_uncertainty_score":0.9999921},"labels":[],"label_agreement":null},{"id":"W2125470506","doi":"10.1038/mtna.2012.28","title":"Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA","year":2012,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":664,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Encana (Canada); Precision Nanosystems (Canada); University of British Columbia","funders":"","keywords":"Dispersity; Microfluidics; In vivo; Small interfering RNA; Gene silencing; RNA interference; Nanotechnology; Chemistry; Nanoparticle; Biophysics; Materials science; RNA; Biology; Biochemistry; Gene","score_opus":0.011854072869904572,"score_gpt":0.23088810265599743,"score_spread":0.21903402978609288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125470506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868902,0.012117916,0.00028057682,0.000088956636,0.00013289484,0.00029348183,0.000047955913,0.000008138369,0.00013990718],"genre_scores_gemma":[0.9940081,0.0046258713,0.0007661998,0.00033788776,0.00008820774,0.000058323916,0.000009198103,0.000042692805,0.00006348473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865943,0.00009563966,0.00042808763,0.00027581808,0.00015242943,0.0003885901],"domain_scores_gemma":[0.99913967,0.000051324274,0.0001557767,0.00044055254,0.00012839555,0.00008428373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027465564,0.00021614708,0.0003228412,0.00007901904,0.000031134103,0.000008622103,0.00031266836,0.00018881395,0.00003486104],"category_scores_gemma":[0.00008408001,0.00020319817,0.00026423746,0.000120672965,0.00011636558,0.000011782675,0.00007698328,0.00005664595,0.0000047059107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058306794,0.0003257018,0.0040088585,0.000036378788,0.00014554423,0.0000017177488,0.00012322194,0.000009410918,0.9856758,0.00004762985,0.00066586834,0.00837677],"study_design_scores_gemma":[0.0007770414,0.0005653954,0.0026273846,0.000046926863,0.000031283274,0.000005129583,0.000105060695,0.000008171489,0.98858,0.000034745382,0.007005337,0.00021353095],"about_ca_topic_score_codex":0.000043665426,"about_ca_topic_score_gemma":0.0000033942058,"teacher_disagreement_score":0.008163239,"about_ca_system_score_codex":0.000017179289,"about_ca_system_score_gemma":0.00004885221,"threshold_uncertainty_score":0.8286181},"labels":[],"label_agreement":null},{"id":"W2151554822","doi":"10.1038/mtna.2011.3","title":"Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells","year":2012,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; Alnylam Pharmaceuticals","keywords":"Gene silencing; RNA interference; Small interfering RNA; Immune system; Myeloid; Biology; Cancer research; In vivo; Inflammation; Immunology; Medicine; RNA; Gene; Genetics","score_opus":0.008436009563338067,"score_gpt":0.23026364634149796,"score_spread":0.2218276367781599,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151554822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988305,0.010080895,0.0008070401,0.000039490813,0.0002432358,0.00026935848,0.000011257392,0.000022906072,0.00022085673],"genre_scores_gemma":[0.99590784,0.0026625306,0.00025963815,0.0007752555,0.00014610149,0.00003195717,0.00006414301,0.000052359344,0.00010014521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985094,0.00011271163,0.00031477926,0.00039367087,0.00017132552,0.0004981345],"domain_scores_gemma":[0.9992772,0.000007824628,0.00009794742,0.0004228807,0.00005006231,0.00014408986],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028502307,0.00026909608,0.00024383428,0.000093897586,0.00006550257,0.000040857107,0.00024301061,0.00021273355,0.000034018696],"category_scores_gemma":[0.000011714531,0.00025519697,0.0000928093,0.000106390726,0.00006997881,0.00001465338,0.00012299648,0.00013597743,0.000059848157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007950691,0.00007870495,0.0061731627,0.000018906489,0.00006208948,0.000017180739,0.00045678666,0.00003998056,0.9908295,0.000010177778,0.000075388816,0.0021585615],"study_design_scores_gemma":[0.0008846426,0.0002539876,0.0054357992,0.00004353885,0.000011497388,0.000058651516,0.00016677819,0.00007813424,0.9915038,0.00001129255,0.0012245767,0.0003273105],"about_ca_topic_score_codex":0.000055657747,"about_ca_topic_score_gemma":0.000008664532,"teacher_disagreement_score":0.00760291,"about_ca_system_score_codex":0.000038645572,"about_ca_system_score_gemma":0.000034385972,"threshold_uncertainty_score":0.99999005},"labels":[],"label_agreement":null},{"id":"W2162278249","doi":"10.1038/mtna.2014.19","title":"Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies","year":2014,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Oncolytic virus; Vesicular stomatitis virus; Virology; Virus; Antibody; Antibody-dependent enhancement; Infectivity; Biology; Neutralizing antibody; Aptamer; Virus quantification; Polyclonal antibodies; Immune system; Vesicular Stomatitis; Viral replication; Molecular biology; Immunology","score_opus":0.02081581563977763,"score_gpt":0.27956437355496166,"score_spread":0.25874855791518403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162278249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898411,0.0017774003,0.0070003034,0.00017728297,0.00011365218,0.0005359504,0.00003867989,0.000051651958,0.00046394768],"genre_scores_gemma":[0.99775416,0.0005811132,0.0007144891,0.0004608598,0.00012100786,0.00005552022,0.00009787683,0.00008213912,0.00013286277],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978263,0.00042654749,0.00037481988,0.0005772884,0.00036824713,0.00042681853],"domain_scores_gemma":[0.99870515,0.000019441588,0.00014757874,0.0008381372,0.0001703903,0.0001193111],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042666023,0.0003110644,0.00034292793,0.00011738369,0.00011690162,0.00003758923,0.0004315354,0.000247908,0.000114048766],"category_scores_gemma":[0.00007494844,0.00030110133,0.00023478459,0.00023859202,0.00023907683,0.000009581345,0.000096255564,0.00020368566,0.00004876663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018865156,0.00012893575,0.0003688887,0.000015046405,0.00022605738,0.000003862613,0.00015440022,0.00020468766,0.9644001,0.000027530094,0.000058749916,0.0325252],"study_design_scores_gemma":[0.0015341266,0.0035367212,0.0014790815,0.000024761981,0.000016031614,0.0000034530765,0.000051045,0.00049489114,0.9799905,0.00037958391,0.012172199,0.00031759898],"about_ca_topic_score_codex":0.00033401902,"about_ca_topic_score_gemma":0.0000783996,"teacher_disagreement_score":0.0322076,"about_ca_system_score_codex":0.00003156745,"about_ca_system_score_gemma":0.00007423466,"threshold_uncertainty_score":0.9999441},"labels":[],"label_agreement":null},{"id":"W2166483989","doi":"10.1038/mtna.2013.65","title":"Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain","year":2013,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Gene knockdown; Small interfering RNA; RNA interference; In vivo; AMPA receptor; Cell biology; Gene expression; Gene delivery; Gene silencing; Biology; NMDA receptor; Chemistry; Receptor; RNA; Neuroscience; Gene; Genetic enhancement; Biochemistry; Genetics","score_opus":0.009848932131436563,"score_gpt":0.23138068370263104,"score_spread":0.22153175157119448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166483989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970388,0.0005744762,0.00083686743,0.00091403583,0.000078552,0.00036427003,0.0000058496917,0.000008140538,0.00017902066],"genre_scores_gemma":[0.9930049,0.00015789625,0.0006571554,0.0059095104,0.00007094362,0.00007181499,0.000014717724,0.000024088868,0.000088977766],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986906,0.00017786553,0.00026371694,0.00035119383,0.00022538986,0.00029120862],"domain_scores_gemma":[0.99919164,0.000020156205,0.0000645733,0.00056040246,0.000090285415,0.00007294617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001896359,0.00017716805,0.00014990076,0.000056090652,0.00004828645,0.000035049612,0.00056079216,0.00010260956,0.00010748651],"category_scores_gemma":[0.000038493316,0.00013334192,0.000108779524,0.00016833445,0.000070814785,0.000012155181,0.00012161358,0.000098388504,0.000069836155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000108320135,0.00010986455,0.001213848,0.0000036221254,0.000014825078,0.0000062846243,0.00031954236,0.00017149422,0.98917234,0.000009461307,0.0017971087,0.0070732767],"study_design_scores_gemma":[0.00044993663,0.00071141863,0.009901418,0.000017829323,0.0000028599777,0.000007728168,0.00016964543,0.00006510764,0.9853285,0.000065292224,0.0031183774,0.0001619123],"about_ca_topic_score_codex":0.000058231766,"about_ca_topic_score_gemma":0.000004924628,"teacher_disagreement_score":0.008687571,"about_ca_system_score_codex":0.000007769824,"about_ca_system_score_gemma":0.000034131583,"threshold_uncertainty_score":0.5437526},"labels":[],"label_agreement":null},{"id":"W2206848875","doi":"10.1038/mtna.2015.33","title":"Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Nicastrin; Disease; Drug development; Alzheimer's disease; Neuroprotection; Drug; Amyloid precursor protein; microRNA; Oxidative stress; Drug discovery; Pharmacology; Biology; Bioinformatics; Medicine; Gene; Internal medicine; Genetics","score_opus":0.05270598466363362,"score_gpt":0.34250374313956433,"score_spread":0.2897977584759307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2206848875","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98536336,0.0103480555,0.0016888868,0.00016080937,0.0006714651,0.0014234368,0.00007518334,0.000027494669,0.00024129622],"genre_scores_gemma":[0.99661946,0.00007018066,0.0017586992,0.00030903955,0.00036151637,0.00015604838,0.00060830027,0.00007740111,0.000039341045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977408,0.00031366764,0.00043803063,0.0005506479,0.0006653197,0.0002915135],"domain_scores_gemma":[0.997986,0.000023406794,0.00023394628,0.00069886557,0.00071458874,0.0003431803],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010103241,0.0002748438,0.00025061244,0.000059949078,0.000058871345,0.0000265454,0.00031861264,0.00021119426,0.00006253763],"category_scores_gemma":[0.00040552946,0.0002728906,0.0003227473,0.000095483454,0.00013707807,0.000013171547,0.00007913911,0.00007701264,0.000014953997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023927737,0.00037356233,0.0012137216,0.000016183049,0.00054451154,0.0000030418123,0.00018220456,0.0022525708,0.9797697,0.00009130583,0.0038935503,0.009266847],"study_design_scores_gemma":[0.012542073,0.00069795165,0.011186957,0.00003678828,0.00071941735,0.000002730959,0.000136092,0.008994577,0.8882833,0.0026592207,0.073964894,0.0007759639],"about_ca_topic_score_codex":0.000030279292,"about_ca_topic_score_gemma":0.0000036228269,"teacher_disagreement_score":0.091486394,"about_ca_system_score_codex":0.00004968646,"about_ca_system_score_gemma":0.0004964823,"threshold_uncertainty_score":0.99997234},"labels":[],"label_agreement":null},{"id":"W2261838712","doi":"10.1038/mtna.2015.58","title":"Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Exon; Duchenne muscular dystrophy; Dystrophin; Biology; Exon skipping; CRISPR; Genome editing; Intron; Genetics; Myogenesis; Gene; Exon shuffling; Open reading frame; Molecular biology; Alternative splicing; Computational biology; Peptide sequence","score_opus":0.006653538760114278,"score_gpt":0.2759622461430878,"score_spread":0.2693087073829735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2261838712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85673434,0.00063028256,0.14205141,0.0001937165,0.000054682027,0.00031146346,0.0000071369677,0.0000047704902,0.00001218797],"genre_scores_gemma":[0.9908869,0.00002230036,0.008890789,0.00008663084,0.000047662063,0.000008768929,0.000001878466,0.000027886403,0.0000271376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990729,0.0001435604,0.000194897,0.00025370618,0.0001542414,0.0001806645],"domain_scores_gemma":[0.9994087,0.000010057741,0.00008089518,0.00042827695,0.00004146821,0.000030553787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022716045,0.00015026274,0.0001247934,0.000038520615,0.000064320855,0.000015173989,0.00019786347,0.00013209949,0.000005373684],"category_scores_gemma":[0.000045423425,0.00008127341,0.00006129608,0.00013043209,0.00007987185,0.0000021590047,0.000090364316,0.00009537715,1.9221709e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004869277,0.000011381107,0.00042613834,0.00000647323,0.000025048561,0.0000013640329,0.00014396729,0.007956761,0.9867394,0.0000685121,0.0000031288334,0.0045691375],"study_design_scores_gemma":[0.00056183175,0.00010836999,0.002817759,0.000044740198,0.000007845163,0.000015880954,0.000033657234,0.0024582602,0.9933674,0.00013389764,0.00033125264,0.00011911215],"about_ca_topic_score_codex":0.000020215815,"about_ca_topic_score_gemma":0.0000067079227,"teacher_disagreement_score":0.1341526,"about_ca_system_score_codex":0.00002187987,"about_ca_system_score_gemma":0.000032365682,"threshold_uncertainty_score":0.33142334},"labels":[],"label_agreement":null},{"id":"W2323582185","doi":"10.1038/mtna.2016.7","title":"Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Huntingtin; Gene silencing; Gene knockdown; Exon; Huntington's disease; Biology; Exon skipping; microRNA; RNA interference; Transgene; Genetics; Gene; Molecular biology; RNA; Mutant; Medicine; Alternative splicing; Disease","score_opus":0.01804486005384942,"score_gpt":0.2661811289913967,"score_spread":0.24813626893754726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2323582185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5659825,0.0004919051,0.43282974,0.000100257574,0.000019409908,0.0005571445,0.0000100862735,0.000007487652,0.0000014719199],"genre_scores_gemma":[0.968679,0.00048888917,0.030062953,0.00016909484,0.00006570821,0.00017622167,0.00008741246,0.000061372346,0.00020931572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987341,0.00008434106,0.0003549982,0.00035298936,0.0001604083,0.00031312506],"domain_scores_gemma":[0.99916124,0.00004151465,0.00021902985,0.00018979161,0.0003102632,0.000078185956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005177413,0.00018773848,0.00021505058,0.00007550614,0.00013866334,0.00001910395,0.0001689282,0.000099972625,0.000009203797],"category_scores_gemma":[0.00009291243,0.00014323609,0.00010941844,0.00009207464,0.00008031571,0.000011429578,0.000027597856,0.000032514647,3.9360188e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012036271,0.00007599367,0.0027876871,0.000041380696,0.00014318868,1.1719819e-7,0.000086582615,0.000003728536,0.8861852,0.000030394176,0.000009630642,0.10943245],"study_design_scores_gemma":[0.002066517,0.00053198193,0.0055147354,0.0000337709,0.000009623888,5.3066725e-7,0.000014857054,0.00022777049,0.9843075,0.000058693386,0.0070499484,0.00018405923],"about_ca_topic_score_codex":0.0000022242787,"about_ca_topic_score_gemma":6.265993e-7,"teacher_disagreement_score":0.4027668,"about_ca_system_score_codex":0.000016030212,"about_ca_system_score_gemma":0.00013921213,"threshold_uncertainty_score":0.5840998},"labels":[],"label_agreement":null},{"id":"W2327475399","doi":"10.1038/mtna.2016.14","title":"A Novel p19 Fusion Protein as a Delivery Agent for Short-interfering RNAs","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Small interfering RNA; RNA interference; Gene knockdown; Cytoplasm; Cell biology; Transactivation; Biology; Fusion protein; RNA; Molecular biology; Chemistry; Transcription factor; Gene; Biochemistry","score_opus":0.018171921764805688,"score_gpt":0.2553642448611577,"score_spread":0.23719232309635202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2327475399","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8823567,0.000878889,0.11506048,0.0003587152,0.00017053357,0.0007078718,0.00003131007,0.000038407397,0.00039708614],"genre_scores_gemma":[0.99424213,0.0004661401,0.0018795932,0.0013197544,0.00019584635,0.00024128363,0.000042653293,0.000084172585,0.001528404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983424,0.000045176723,0.00030589293,0.00063955603,0.00020562307,0.00046137758],"domain_scores_gemma":[0.99902344,0.000009551552,0.000075720876,0.0006132876,0.00016267014,0.00011530892],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017892786,0.0003275457,0.00022943919,0.000076547636,0.00011184113,0.00005088211,0.00044234257,0.00023465685,0.000095026655],"category_scores_gemma":[0.000044092227,0.00024565143,0.0003210132,0.00007449336,0.000084029445,0.000012469635,0.00017304873,0.00007656168,0.00007037832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077148376,0.00011495609,0.00007898745,0.000011244275,0.00015121947,0.000012414937,0.00004740835,0.000006511371,0.92504585,0.00008329474,0.00038646156,0.073290154],"study_design_scores_gemma":[0.0014362545,0.0015183241,0.00015149453,0.000100626545,0.000014822496,0.000029738854,0.000041579664,0.000041621708,0.9300215,0.00013307916,0.066132195,0.00037874552],"about_ca_topic_score_codex":0.000025075085,"about_ca_topic_score_gemma":0.000009854523,"teacher_disagreement_score":0.11318088,"about_ca_system_score_codex":0.000041949883,"about_ca_system_score_gemma":0.000074802585,"threshold_uncertainty_score":0.9999996},"labels":[],"label_agreement":null},{"id":"W2518717287","doi":"10.1038/mtna.2016.68","title":"Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Sclerostin; Gene silencing; Gene knockdown; Osteocyte; Cell biology; Chemistry; Osteoblast; Small interfering RNA; RNA interference; Wnt signaling pathway; In vivo; In vitro; Transfection; Gene; Biology; Signal transduction; RNA; Biochemistry; Genetics","score_opus":0.007169913584867142,"score_gpt":0.2234887960424006,"score_spread":0.21631888245753345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2518717287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982496,0.00040842875,0.00075544015,0.00009550307,0.0000370705,0.00035089444,0.00002878183,0.000004500041,0.00006978901],"genre_scores_gemma":[0.9991476,0.000172996,0.00035344673,0.00023776924,0.00002185844,0.000022537954,0.000002370159,0.000020022326,0.00002137796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989979,0.00008645558,0.00030795686,0.0002864549,0.00013203236,0.00018917593],"domain_scores_gemma":[0.99938977,0.000028026876,0.00009925416,0.00026616518,0.00014766073,0.00006911731],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018564962,0.00014518716,0.00024338518,0.00011491956,0.000016802058,0.000004981733,0.00012040822,0.00009771291,0.000019824278],"category_scores_gemma":[0.000071192626,0.00011889265,0.00007507929,0.00016527623,0.00009326203,0.000009763333,0.00010972181,0.000033519922,0.0000037872019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059708895,0.00007382231,0.007679348,0.000020973777,0.000030998308,0.000002385935,0.0003323741,0.00004443639,0.97527826,0.00001772318,0.00003219537,0.015890384],"study_design_scores_gemma":[0.0009612676,0.0021460836,0.008830372,0.00022637844,0.0000074844834,0.0000019400027,0.00009243032,0.0000067263404,0.98748934,0.000031634438,0.000066738925,0.00013958375],"about_ca_topic_score_codex":0.000061930616,"about_ca_topic_score_gemma":0.000026998896,"teacher_disagreement_score":0.015750801,"about_ca_system_score_codex":0.000016024791,"about_ca_system_score_gemma":0.000028647131,"threshold_uncertainty_score":0.48483014},"labels":[],"label_agreement":null},{"id":"W2521908034","doi":"10.1038/mtna.2016.69","title":"Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; National Institutes of Health; Gebert Rüf Stiftung; Eidgenössische Technische Hochschule Zürich","keywords":"Transfection; Gene silencing; Nucleic acid; Chemistry; Oligonucleotide; Genetic enhancement; Cell culture; Molecular biology; Biology; Biochemistry; Gene","score_opus":0.007369772765773766,"score_gpt":0.21378543669109396,"score_spread":0.20641566392532018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2521908034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932499,0.003029968,0.0024960719,0.00039400544,0.00022939697,0.00028603987,0.00011110463,0.00005354751,0.00014995996],"genre_scores_gemma":[0.9968218,0.0012656265,0.0002499084,0.0010098044,0.000102686034,0.00004680605,0.000100949925,0.000095178875,0.00030720825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976457,0.00017946724,0.00046198844,0.00080014736,0.00026894963,0.0006437951],"domain_scores_gemma":[0.9985269,0.00002014664,0.00014251292,0.0010032575,0.00012401947,0.00018319],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018753445,0.00045851158,0.0003588451,0.00012430378,0.000090920475,0.00006189907,0.0008720372,0.0003008311,0.00023379999],"category_scores_gemma":[0.00006894314,0.00036079227,0.00021523915,0.00019241056,0.00021061942,0.000017793513,0.0002616552,0.0001729561,0.00007075164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026998928,0.00012148254,0.0027033936,0.000007657215,0.00010666797,0.00003901298,0.00009152917,0.00000528672,0.98770285,0.000017036735,0.0016407563,0.007294365],"study_design_scores_gemma":[0.0024390558,0.00075391185,0.0013070435,0.000076245284,0.00001571462,0.000022620457,0.000052182357,0.0000341914,0.9917031,0.00029814368,0.002779873,0.00051791256],"about_ca_topic_score_codex":0.00008853003,"about_ca_topic_score_gemma":0.000030543684,"teacher_disagreement_score":0.006776453,"about_ca_system_score_codex":0.000058463997,"about_ca_system_score_gemma":0.00007421237,"threshold_uncertainty_score":0.9998844},"labels":[],"label_agreement":null},{"id":"W2556873809","doi":"10.1038/mtna.2016.43","title":"A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Prostate Cancer Canada; Alnylam Pharmaceuticals","keywords":"Prostate cancer; Androgen receptor; Small interfering RNA; Chemistry; Cancer research; Prostate; Cancer; Transfection; Biology; Biochemistry; Internal medicine; Medicine","score_opus":0.00836348994413173,"score_gpt":0.22115305259919565,"score_spread":0.21278956265506394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2556873809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959973,0.0017208604,0.00076328026,0.00029029264,0.0002639258,0.00038167313,0.000034131266,0.000067662084,0.00048088288],"genre_scores_gemma":[0.9976966,0.00070409244,0.00023728414,0.0005475272,0.00017725218,0.000077238896,0.000024923225,0.000073622075,0.00046148984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978477,0.00019988017,0.0004672919,0.0006993058,0.0002574079,0.0005284317],"domain_scores_gemma":[0.9988575,0.000012330005,0.00014192703,0.0006958046,0.000121190664,0.00017123787],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026919175,0.0003613099,0.00032649733,0.00010955468,0.00008849199,0.000053144726,0.00041313402,0.00034111424,0.0001141837],"category_scores_gemma":[0.000038329592,0.00026334287,0.00018779084,0.00020454303,0.00010080707,0.000020927968,0.0001470224,0.00010757988,0.00015738535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006128005,0.000110350855,0.0016547795,0.000014811028,0.000072734714,0.00003108366,0.000114040144,0.000007740691,0.989969,0.000029716743,0.001229358,0.006153563],"study_design_scores_gemma":[0.0023456695,0.0006201205,0.00016157047,0.0002495071,0.0000097238935,0.000028203165,0.00009451973,0.000021528667,0.9776061,0.000020388981,0.018446939,0.00039569254],"about_ca_topic_score_codex":0.000023820374,"about_ca_topic_score_gemma":0.000012371483,"teacher_disagreement_score":0.01721758,"about_ca_system_score_codex":0.000060390732,"about_ca_system_score_gemma":0.000070240334,"threshold_uncertainty_score":0.9999819},"labels":[],"label_agreement":null},{"id":"W2564010196","doi":"10.1016/j.omtn.2016.12.002","title":"Aptamers for CD Antigens: From Cell Profiling to Activity Modulation","year":2016,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aptamer; Nucleic acid; Flow cytometry; Biology; Cell; Antigen; Molecular biology; Chemistry; Computational biology; Biochemistry; Immunology","score_opus":0.024552807670697577,"score_gpt":0.32201345803113846,"score_spread":0.2974606503604409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2564010196","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017320096,0.87206686,0.10733281,0.00006936664,0.00019689558,0.002224451,0.0005339501,0.00013116395,0.00012441596],"genre_scores_gemma":[0.013542127,0.9571764,0.0270834,0.0002913172,0.00042400596,0.00017154004,0.00084696483,0.00019134264,0.0002729267],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975682,0.00018458383,0.0004444478,0.0011213169,0.00022602521,0.00045546403],"domain_scores_gemma":[0.9982643,0.000030842857,0.0003762294,0.0010430961,0.00014496535,0.00014055394],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002218098,0.0006494577,0.0010798043,0.00015662698,0.0001302179,0.000057595982,0.0004472342,0.00069876295,0.0000048915535],"category_scores_gemma":[0.00005212689,0.0004914001,0.00096041913,0.00021541493,0.00007680777,0.0000070032975,0.00012750499,0.00016359237,0.000018391624],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058286223,0.000038899503,0.0000017606009,0.00015511211,0.00020418652,0.0000023705074,0.000003664405,7.531724e-7,0.42965195,0.000003806756,0.000104415245,0.5697748],"study_design_scores_gemma":[0.00025494426,0.00022972011,0.0000019866284,0.0005357483,0.00012536564,0.0000020183234,0.0000027561875,0.000011710653,0.37277693,0.000060571045,0.62548685,0.0005113906],"about_ca_topic_score_codex":0.000007562052,"about_ca_topic_score_gemma":0.000002045002,"teacher_disagreement_score":0.6253824,"about_ca_system_score_codex":0.00007286758,"about_ca_system_score_gemma":0.000116056544,"threshold_uncertainty_score":0.9997538},"labels":[],"label_agreement":null},{"id":"W256521491","doi":"10.1038/mtna.2015.13","title":"Progress in RNAi-mediated Molecular Therapy of Acute and Chronic Myeloid Leukemia","year":2015,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Blood Services; BC Cancer Agency; University of British Columbia; University of Alberta","funders":"","keywords":"RNA interference; Myeloid leukemia; Haematopoiesis; Leukemia; Cancer research; Progenitor cell; Genetic enhancement; Context (archaeology); Small interfering RNA; Myeloid; Biology; Stem cell; Immunology; Medicine; RNA; Cell biology; Gene; Genetics","score_opus":0.018517465043592387,"score_gpt":0.2970700542225466,"score_spread":0.27855258917895426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W256521491","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14686134,0.851596,0.000089900444,0.000025230118,0.00014250867,0.0010238641,0.000089378285,0.000024116222,0.00014764805],"genre_scores_gemma":[0.0150305955,0.9831019,0.00020237133,0.00022677876,0.00012530407,0.00021807848,0.00080103165,0.00019502694,0.00009892507],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966219,0.00039740818,0.00090282527,0.0010381613,0.00040984008,0.000629885],"domain_scores_gemma":[0.99796736,0.000014566214,0.00049663463,0.0011118008,0.00020587652,0.00020373656],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004168789,0.0008841692,0.0016751712,0.00029527114,0.000043925105,0.00006005052,0.00088446884,0.0010198769,0.000035980327],"category_scores_gemma":[0.000016205515,0.00075302285,0.00059565465,0.00043427132,0.00039232697,0.000012359357,0.0002667456,0.00047100705,0.00003373151],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020883404,0.0001395306,0.0000697328,0.00066541624,0.0015910349,0.00021207624,0.000081444305,0.0000037974705,0.081307,0.000022516997,0.00024167023,0.91545695],"study_design_scores_gemma":[0.002540156,0.002261104,0.000037115708,0.001626227,0.00020736958,0.00011589379,0.000018906245,0.000019153047,0.052147906,0.000059481514,0.9398576,0.0011090754],"about_ca_topic_score_codex":0.000017474838,"about_ca_topic_score_gemma":0.000004859222,"teacher_disagreement_score":0.93961596,"about_ca_system_score_codex":0.00018025374,"about_ca_system_score_gemma":0.0010249506,"threshold_uncertainty_score":0.99949205},"labels":[],"label_agreement":null},{"id":"W2565581989","doi":"10.1016/j.omtn.2016.11.004","title":"Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Alpha (finance); Protein subunit; Expression (computer science); Laminin; Cell biology; Chemistry; Computational biology; Biology; Computer science; Genetics; Psychology; Programming language; Gene; Developmental psychology","score_opus":0.01495120474776331,"score_gpt":0.2738571889609893,"score_spread":0.258905984213226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565581989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895878,0.0014778629,0.00398466,0.0014649115,0.00005014689,0.0006546954,0.000034748336,0.000104982115,0.0026401903],"genre_scores_gemma":[0.99365145,0.00070728693,0.0012063564,0.0010061748,0.00005123716,0.00004892156,0.00004795471,0.0001250894,0.0031555083],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971394,0.0003311357,0.00046796448,0.000533191,0.0009793087,0.00054903206],"domain_scores_gemma":[0.9980862,0.00014226716,0.0001508792,0.0010295163,0.00022232992,0.0003687983],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004858249,0.0003245588,0.00051392097,0.0002585573,0.00007313381,0.000017861943,0.00039603355,0.00025057213,0.0025417798],"category_scores_gemma":[0.00020219428,0.00021778358,0.00024481004,0.0003926894,0.00027058163,0.00007791053,0.00014647696,0.00023949868,0.0002144944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009593666,0.0003767977,0.0026682026,0.000034922585,0.000073114854,0.00018515252,0.00012011155,1.8475389e-7,0.9550111,0.0000766953,0.004120096,0.03637422],"study_design_scores_gemma":[0.0053453273,0.0009391436,0.0031028755,0.00020999648,0.000020819189,0.000031905307,0.000053980366,0.00002968875,0.94621897,0.00011674271,0.04368488,0.0002456624],"about_ca_topic_score_codex":0.000055039804,"about_ca_topic_score_gemma":9.21265e-7,"teacher_disagreement_score":0.039564785,"about_ca_system_score_codex":0.00009879818,"about_ca_system_score_gemma":0.00013020722,"threshold_uncertainty_score":0.99837005},"labels":[],"label_agreement":null},{"id":"W2565794103","doi":"10.1016/j.omtn.2016.12.004","title":"DNA Aptamers for the Characterization of Histological Structure of Lung Adenocarcinoma","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Tomsk State University; Ministry of Education and Science of the Russian Federation","keywords":"Aptamer; Adenocarcinoma; Lung cancer; Monoclonal antibody; Nucleic acid; Biology; Targeted therapy; Oligonucleotide; DNA; Cancer research; Computational biology; Pathology; Molecular biology; Cancer; Antibody; Chemistry; Medicine; Immunology; Biochemistry; Genetics","score_opus":0.010940212528330663,"score_gpt":0.2669756289421458,"score_spread":0.25603541641381516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565794103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9823881,0.00040154622,0.016483705,0.0002852824,0.00006116296,0.0002767332,0.000060081948,0.000010881063,0.000032546763],"genre_scores_gemma":[0.9972828,0.00030733988,0.001976319,0.00019526579,0.00005806349,0.000006313319,0.00009929632,0.000021091031,0.000053505722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923724,0.0000386758,0.00021533108,0.00024620508,0.000118448785,0.00014410635],"domain_scores_gemma":[0.99872255,0.000008885943,0.00037019927,0.00073774793,0.00013416141,0.000026450254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009513614,0.00014590388,0.00021255646,0.000028124026,0.0001669799,0.000017352766,0.00042024546,0.00017155254,0.0000043973832],"category_scores_gemma":[0.00006385033,0.00009733106,0.00020455824,0.00003777314,0.0003314914,0.0000048358725,0.00006996291,0.000059324197,9.5361735e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018798221,0.000025624184,0.002207345,0.00001101456,0.00014826946,8.3334777e-7,0.000021101421,0.0000010583553,0.98862267,0.00013123751,0.00002758545,0.0086152665],"study_design_scores_gemma":[0.00036949367,0.000255473,0.01891545,0.000009143854,0.00005235269,0.000004274571,0.000012949147,0.00013180308,0.977152,0.00012283908,0.002856744,0.00011747446],"about_ca_topic_score_codex":0.0000054057746,"about_ca_topic_score_gemma":0.000001945563,"teacher_disagreement_score":0.016708106,"about_ca_system_score_codex":0.000008581291,"about_ca_system_score_gemma":0.000021927783,"threshold_uncertainty_score":0.39690453},"labels":[],"label_agreement":null},{"id":"W2606874422","doi":"10.1016/j.omtn.2017.04.017","title":"Further Characterization of the Bifunctional HIV Entry Inhibitor sCD4-FI T45","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Health Canada","keywords":"Entry inhibitor; Epitope; Bifunctional; Antibody; Glycoprotein; Cell fusion; Chemistry; Fusion protein; Cell biology; Virology; Cell; Viral entry; Biology; Virus; Biochemistry; Immunology; Viral replication; Gene; Recombinant DNA","score_opus":0.01020538142269828,"score_gpt":0.23467962242636958,"score_spread":0.2244742410036713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606874422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99505305,0.00047571032,0.00028261665,0.0019064142,0.00048437394,0.0003012787,0.0001044446,0.000024282219,0.001367847],"genre_scores_gemma":[0.99588513,0.00013672111,0.000024281382,0.00023524242,0.00004617228,0.000029550316,0.00016975892,0.000022455184,0.003450698],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913085,0.00014583662,0.00016587706,0.0002153956,0.0000897672,0.0002522908],"domain_scores_gemma":[0.9990482,0.000012529696,0.00015114539,0.000692544,0.000071165894,0.000024444471],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011323857,0.00014633578,0.00016159791,0.00004362851,0.00040166746,0.000036038124,0.00040356445,0.00015112624,0.0013438382],"category_scores_gemma":[0.000029999948,0.000095676005,0.00015115459,0.000049644244,0.0003232177,0.0000843366,0.00011068266,0.00016988517,0.0007671075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022035089,0.00018866744,0.014777992,0.0000041153376,0.00027428154,0.0000059679314,0.00019719149,5.117657e-7,0.9695273,0.0002656712,0.00034239568,0.0141955735],"study_design_scores_gemma":[0.0022018598,0.00015182588,0.18625303,0.000023033095,0.000015581845,0.000013411157,0.000021558297,0.000001941161,0.7365661,0.00009118412,0.074553505,0.00010692285],"about_ca_topic_score_codex":0.00001926763,"about_ca_topic_score_gemma":0.0000017384656,"teacher_disagreement_score":0.23296113,"about_ca_system_score_codex":0.000029860303,"about_ca_system_score_gemma":0.00006274383,"threshold_uncertainty_score":0.99956906},"labels":[],"label_agreement":null},{"id":"W2611427234","doi":"10.1016/j.omtn.2017.04.019","title":"Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Quebec Rehabilitation Research Network","funders":"","keywords":"Nap; Nucleic acid; Chronic hepatitis; Biology; Virology; Virus; Biochemistry","score_opus":0.024113319256572716,"score_gpt":0.2889684732974779,"score_spread":0.26485515404090515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2611427234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839628,0.008860828,0.0008650665,0.002842749,0.00017838724,0.0016984467,0.000041588613,0.00018156422,0.0013685767],"genre_scores_gemma":[0.9831454,0.0118931895,0.001972477,0.0017303246,0.00019940657,0.00023999711,0.000024882698,0.00020123267,0.0005931038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779254,0.00006506573,0.00033516323,0.0007115471,0.00040673977,0.00068895466],"domain_scores_gemma":[0.9981827,0.00003449143,0.0002471801,0.0011000629,0.00020070307,0.00023485924],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017622142,0.00050502486,0.0007239931,0.00011423234,0.00090222684,0.00022401627,0.00038627625,0.00021304043,0.00028745958],"category_scores_gemma":[0.000057286223,0.0004101578,0.00013151675,0.00013102333,0.0006026759,0.00026560616,0.00008500742,0.00027107162,0.00005014904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028011326,0.000204423,0.05414972,0.00009942247,0.0010307333,0.0002799505,0.00095296395,0.0000034316442,0.5289659,0.0003011208,0.00049681816,0.41071442],"study_design_scores_gemma":[0.016914472,0.006789839,0.29340845,0.00032198036,0.00011929588,0.00014620795,0.00004123603,0.0007190559,0.5773395,0.0001364755,0.10314207,0.00092144636],"about_ca_topic_score_codex":0.0010088694,"about_ca_topic_score_gemma":0.00050541933,"teacher_disagreement_score":0.40979296,"about_ca_system_score_codex":0.00013527059,"about_ca_system_score_gemma":0.00015754989,"threshold_uncertainty_score":0.999835},"labels":[],"label_agreement":null},{"id":"W2613065760","doi":"10.1016/j.omtn.2017.05.002","title":"Efficacy of Postnatal In Vivo Nonsense Suppression Therapy in a Pax6 Mouse Model of Aniridia","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; University of British Columbia","funders":"","keywords":"Aniridia; PAX6; Nonsense mutation; Nonsense; In vivo; Biology; Pharmacology; Medicine; Ophthalmology; Missense mutation; Genetics; Mutation; Gene","score_opus":0.013431757755883286,"score_gpt":0.2608573217238483,"score_spread":0.247425563967965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2613065760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978204,0.0006825913,0.0002811579,0.00010693584,0.000039785486,0.0003340593,0.000020349617,0.00000591544,0.0007088205],"genre_scores_gemma":[0.99706763,0.0017491666,0.00082608615,0.00013492422,0.000010558824,0.000013478109,0.000028721166,0.000039088438,0.0001303726],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987605,0.00007910082,0.0003547176,0.0003452783,0.00020097873,0.0002594189],"domain_scores_gemma":[0.9989525,0.000009692532,0.00020282161,0.0007214014,0.00006130874,0.00005227235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021455191,0.00021716591,0.0002825054,0.00010986659,0.00005092183,0.000019982319,0.0004760569,0.00020106557,0.000024847408],"category_scores_gemma":[0.00006603672,0.00019811829,0.00014075337,0.0000676463,0.00017204312,0.000011074066,0.00011823633,0.00010428345,0.0000015325663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019221727,0.00030192934,0.017311987,0.000011064366,0.000036693833,0.000014481375,0.0002974898,0.00040298622,0.97710526,0.000038607144,0.000068553236,0.0024887903],"study_design_scores_gemma":[0.0045765024,0.0003371884,0.021402325,0.00003515683,0.0000026092048,0.0000023663504,0.000044442168,0.00059735373,0.97240955,0.000085875174,0.0002845054,0.00022211495],"about_ca_topic_score_codex":0.00010345622,"about_ca_topic_score_gemma":0.000020663887,"teacher_disagreement_score":0.004695686,"about_ca_system_score_codex":0.00001069019,"about_ca_system_score_gemma":0.00009447884,"threshold_uncertainty_score":0.80790293},"labels":[],"label_agreement":null},{"id":"W2616392786","doi":"10.1016/j.omtn.2017.05.007","title":"Targeting DMPK with Antisense Oligonucleotide Improves Muscle Strength in Myotonic Dystrophy Type 1 Mice","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Hôpital de l'Enfant-Jésus","funders":"National Institute of Neurological Disorders and Stroke; Ionis Pharmaceuticals; Muscular Dystrophy Association","keywords":"Myotonic dystrophy; Trinucleotide repeat expansion; RNA splicing; Myotonia; Biology; Muscular dystrophy; Alternative splicing; Untranslated region; Skeletal muscle; Gene; Genetics; Dystrophin; Molecular biology; Messenger RNA; RNA; Allele; Endocrinology","score_opus":0.015312607338422516,"score_gpt":0.2524692068329085,"score_spread":0.237156599494486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2616392786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99761134,0.00027083958,0.00016105876,0.00030664523,0.0002175722,0.0005780958,0.000018102706,0.00010144262,0.00073490274],"genre_scores_gemma":[0.9967371,0.00029902195,0.0015776231,0.001058474,0.000061403596,0.000030975807,0.000005001379,0.00012100662,0.00010938925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99736345,0.00027679367,0.0003132531,0.00096383604,0.00043754236,0.0006451181],"domain_scores_gemma":[0.9982759,0.00005903248,0.0002617229,0.0011364048,0.000086269516,0.00018068947],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013005326,0.0004100486,0.0003335352,0.00013061968,0.0004892592,0.00033859527,0.0009473141,0.00008428558,0.000073577125],"category_scores_gemma":[0.0002983794,0.00035882418,0.00010350186,0.00024882163,0.00038455616,0.00031246903,0.00018360499,0.00028334398,0.00008267019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036084716,0.00018447537,0.0014571184,0.000011127805,0.000014289645,0.00041731793,0.00015799586,0.00028127423,0.9919803,0.00019784796,0.00002831484,0.0049090637],"study_design_scores_gemma":[0.0021649995,0.00055283285,0.026751246,0.00003282472,0.000014162471,0.0000118629,0.000053879226,0.0010006754,0.96776104,0.00012237387,0.0010954946,0.00043858288],"about_ca_topic_score_codex":0.00007131567,"about_ca_topic_score_gemma":0.000009887321,"teacher_disagreement_score":0.025294129,"about_ca_system_score_codex":0.000044298507,"about_ca_system_score_gemma":0.00010761497,"threshold_uncertainty_score":0.9998864},"labels":[],"label_agreement":null},{"id":"W2730933490","doi":"10.1016/j.omtn.2017.07.001","title":"MicroRNA-31 Regulates Chemosensitivity in Malignant Pleural Mesothelioma","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Hull York Medical School; University of Hull","keywords":"Mesothelioma; microRNA; Cancer research; Medicine; Oncology; Internal medicine; Biology; Pathology; Gene; Genetics","score_opus":0.014257435192387457,"score_gpt":0.26369599506487335,"score_spread":0.2494385598724859,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2730933490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99520445,0.00070420076,0.000021929482,0.0018991646,0.000060360882,0.00028299793,0.00001535592,0.000038918548,0.0017726282],"genre_scores_gemma":[0.99722105,0.00012512275,0.0004615454,0.0013732632,0.000061227474,0.0000128400425,0.000040623734,0.0000386697,0.00066564407],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99894285,0.000034018987,0.00018309637,0.00031614924,0.00025581513,0.0002680723],"domain_scores_gemma":[0.9991262,0.000012040732,0.00009043088,0.00062738656,0.000017826753,0.00012614182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011176413,0.0001980979,0.0002601912,0.00006541792,0.00015607422,0.000049570386,0.00017120695,0.000088178065,0.0001598499],"category_scores_gemma":[0.000027522452,0.00016528627,0.00015508254,0.000055084933,0.00020582975,0.00010647754,0.0000769278,0.00010859374,0.00011624508],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060528057,0.00029452465,0.19026515,0.000014924997,0.000068957954,0.0005647649,0.000061270206,0.0000048882757,0.7982129,0.000100564204,0.00015053553,0.009656269],"study_design_scores_gemma":[0.0016320169,0.00012095644,0.70539564,0.00005725493,0.00001828883,0.00004941526,0.000017398941,0.00009008098,0.29038355,0.00035146932,0.001736647,0.00014729671],"about_ca_topic_score_codex":0.000100421144,"about_ca_topic_score_gemma":0.0000049703267,"teacher_disagreement_score":0.51513046,"about_ca_system_score_codex":0.00008230708,"about_ca_system_score_gemma":0.000030257384,"threshold_uncertainty_score":0.67401785},"labels":[],"label_agreement":null},{"id":"W2748181778","doi":"10.1016/j.omtn.2017.08.007","title":"Aptamer-Targeted Plasmonic Photothermal Therapy of Cancer","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Photothermal therapy; Aptamer; Plasmon; Cancer therapy; Nanotechnology; Cancer; Materials science; Medicine; Biology; Optoelectronics; Molecular biology; Internal medicine","score_opus":0.012175542514645159,"score_gpt":0.24621571639888715,"score_spread":0.23404017388424198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2748181778","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9831427,0.012067851,0.001349649,0.00006697441,0.0007939866,0.00042900274,0.000068815985,0.00026699094,0.0018140749],"genre_scores_gemma":[0.9900285,0.008651538,0.0005911624,0.00024164477,0.00008801445,0.00007512033,0.000010347939,0.00021405399,0.00009963946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843127,0.000020672322,0.00037233272,0.00029374406,0.00036751537,0.00051447557],"domain_scores_gemma":[0.9983773,0.000019964435,0.00018209794,0.0012217306,0.00008156335,0.00011729185],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000121272846,0.00040092092,0.0004514364,0.00010794494,0.00019489983,0.000091508504,0.00094130886,0.00021375176,0.000661476],"category_scores_gemma":[0.000011466715,0.0003698408,0.0002281189,0.00013197465,0.00021363201,0.0002429824,0.000047581878,0.00026866264,0.000039465423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017622003,0.000047850765,0.0018870686,0.000020561258,0.00050337595,0.000020929394,0.00033199796,0.0014943304,0.91435987,0.00010037174,0.000118104625,0.080939345],"study_design_scores_gemma":[0.002713462,0.00016137998,0.006924327,0.00005010463,0.000016270451,0.0000033434019,0.000020872265,0.0023698835,0.9614657,0.00038646194,0.025426773,0.00046141597],"about_ca_topic_score_codex":0.00018293143,"about_ca_topic_score_gemma":0.000019983045,"teacher_disagreement_score":0.08047793,"about_ca_system_score_codex":0.00010262444,"about_ca_system_score_gemma":0.000059100992,"threshold_uncertainty_score":0.99987537},"labels":[],"label_agreement":null},{"id":"W2759926442","doi":"10.1016/j.omtn.2017.08.017","title":"Control of HIV Infection In Vivo Using Gene Therapy with a Secreted Entry Inhibitor","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Sunnybrook Health Science Centre; Sunnybrook Hospital; University of Toronto","funders":"Krembil Foundation; Canadian Institutes of Health Research; Canadian Foundation for AIDS Research","keywords":"Genetic enhancement; Progenitor cell; Ex vivo; Biology; Haematopoiesis; Virology; CD34; In vivo; Gene delivery; Glycoprotein; Viral vector; Stem cell; Immunology; Molecular biology; Gene; Cell biology; Recombinant DNA","score_opus":0.01257402064952656,"score_gpt":0.2556890551291387,"score_spread":0.24311503447961214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2759926442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99489677,0.0019819452,0.0020276906,0.000121830584,0.00009213368,0.00053336436,0.00005015415,0.000027885611,0.00026824363],"genre_scores_gemma":[0.9989598,0.00055872044,0.0001605408,0.00009539117,0.000018611292,0.000035670673,0.000031002986,0.000030796964,0.000109484616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888134,0.00021103026,0.00020484829,0.00027061717,0.000074673146,0.000357495],"domain_scores_gemma":[0.9991707,0.000020730311,0.00015977678,0.0005424689,0.00007284637,0.000033475346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015914862,0.00020007775,0.0003145966,0.00012653475,0.00021762427,0.000032294218,0.00020029832,0.00018686279,0.00036636455],"category_scores_gemma":[0.000017347109,0.00014963736,0.00009809707,0.000079104946,0.00026935214,0.00009778511,0.000031324744,0.00019915205,0.00005083633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017691962,0.00028872653,0.083783835,0.0000046433283,0.0004683269,0.00006765649,0.00018405891,0.000026398347,0.9087711,0.000036368794,0.000023733684,0.0045759366],"study_design_scores_gemma":[0.014741891,0.00095231796,0.03372929,0.00004236323,0.000015628888,0.000039799586,0.000013787216,0.00004120699,0.9460786,0.00003492496,0.004142503,0.00016771407],"about_ca_topic_score_codex":0.0005909358,"about_ca_topic_score_gemma":0.000030357154,"teacher_disagreement_score":0.050054543,"about_ca_system_score_codex":0.000061529536,"about_ca_system_score_gemma":0.0000858054,"threshold_uncertainty_score":0.61020344},"labels":[],"label_agreement":null},{"id":"W2773124324","doi":"10.1016/j.omtn.2017.11.012","title":"Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice","year":2017,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canada Research Chairs; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Rare Diseases Clinical Research Network; Rare Disease Foundation; National Center for Advancing Translational Sciences; BC Children’s Hospital Foundation","keywords":"Transcription activator-like effector nuclease; Induced pluripotent stem cell; Arginase; Biology; Effector; Transplantation; Cell biology; Embryonic stem cell; Molecular biology; Genome editing; Cancer research; Gene; Genetics; Arginine; CRISPR; Medicine","score_opus":0.009508594802257408,"score_gpt":0.26875770787647724,"score_spread":0.25924911307421983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2773124324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94456726,0.000975601,0.05353066,0.000027296723,0.00031318358,0.00023246984,0.000066477,0.000012189309,0.00027488547],"genre_scores_gemma":[0.9963611,0.0009802053,0.002337246,0.000051433468,0.000060136008,0.000012251378,0.00007134037,0.000046687626,0.00007962654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885595,0.00004406115,0.00029892277,0.0003328743,0.00022836079,0.0002398206],"domain_scores_gemma":[0.9988673,0.000007425247,0.00019413586,0.0007450163,0.0001162618,0.00006990209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172927,0.00021681213,0.00025323985,0.0000571143,0.00008576883,0.000024379655,0.00042920487,0.00016154592,0.0000111233685],"category_scores_gemma":[0.000012161268,0.00021721802,0.00018978876,0.000050559716,0.00013095813,0.000006558977,0.000042580057,0.00007477193,0.0000020597035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022527951,0.00008861755,0.0004901183,0.0000652548,0.00009717532,0.000008360488,0.00014377577,0.0014599548,0.995103,0.000033376244,0.000016865473,0.0022681984],"study_design_scores_gemma":[0.0011884668,0.00034439642,0.0046576257,0.000018423363,0.0000323938,0.000007346563,0.000038299902,0.0011683166,0.9910128,0.000018775052,0.0012916087,0.00022154696],"about_ca_topic_score_codex":0.00006220556,"about_ca_topic_score_gemma":0.000008126917,"teacher_disagreement_score":0.051793836,"about_ca_system_score_codex":0.000008265999,"about_ca_system_score_gemma":0.000040544015,"threshold_uncertainty_score":0.8857894},"labels":[],"label_agreement":null},{"id":"W2791875139","doi":"10.1016/j.omtn.2018.03.007","title":"CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer’s Disease","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Common Fund; Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; National Institutes of Health; Marcus och Amalia Wallenbergs minnesfond; Hjärnfonden; National Center for Research Resources; National Institute of General Medical Sciences; Kosciuszko Foundation","keywords":"CRISPR; Amyloid precursor protein; Biology; Mutant; Allele; Cas9; Point mutation; Gene; Transgene; Genetics; Molecular biology; Alzheimer's disease; Disease; Medicine; Pathology","score_opus":0.014089067671773682,"score_gpt":0.2980079156000912,"score_spread":0.2839188479283175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791875139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8944419,0.0046666567,0.09917407,0.00022473263,0.00017984862,0.0008780003,0.0000691081,0.000037431066,0.0003282312],"genre_scores_gemma":[0.9970347,0.0002124435,0.0012224226,0.0007935963,0.00020002718,0.0001386378,0.00019818764,0.00008297573,0.00011696632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985779,0.000089696565,0.00027105052,0.00045087503,0.00025142982,0.00035902584],"domain_scores_gemma":[0.99882007,0.00001352619,0.00010338359,0.0007801724,0.00014446028,0.00013840587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019311305,0.00027624497,0.00020744532,0.00004388852,0.00013461114,0.000030695268,0.00046563902,0.0001507102,0.000035751906],"category_scores_gemma":[0.00005238909,0.00021588682,0.00030032423,0.0001695763,0.00023875703,0.0000057644397,0.00010243198,0.00009877642,0.000008526314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008775669,0.00027547876,0.004171574,0.000034148947,0.00057057926,0.0000026356843,0.0003642859,0.00023410562,0.985289,0.00015119325,0.00083209085,0.007197383],"study_design_scores_gemma":[0.0024510243,0.001114256,0.028313586,0.000019688818,0.00021858065,0.000018131048,0.00013431776,0.0026264384,0.9288619,0.0005380959,0.035095077,0.0006088757],"about_ca_topic_score_codex":0.000017995057,"about_ca_topic_score_gemma":0.000002697182,"teacher_disagreement_score":0.10259282,"about_ca_system_score_codex":0.000010209492,"about_ca_system_score_gemma":0.00006910752,"threshold_uncertainty_score":0.8803609},"labels":[],"label_agreement":null},{"id":"W2801624157","doi":"10.1016/j.omtn.2018.04.009","title":"Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Fonds de Recherche du Québec - Santé; Ataxia Canada","keywords":"Frataxin; Biology; Intron; Gene; Ataxia; Gene expression; Effector; Molecular biology; Iron-binding proteins; Genetics; Cell biology","score_opus":0.022955993265722747,"score_gpt":0.268523393204963,"score_spread":0.24556739993924023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801624157","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99572104,0.00015432214,0.0010153226,0.0001370615,0.00042634035,0.0011338226,0.00024330078,0.00020351067,0.0009652577],"genre_scores_gemma":[0.9938222,0.00005466882,0.00089425483,0.0042227227,0.0001605624,0.00014879678,0.000054984823,0.00018930018,0.00045250394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9948613,0.0009323657,0.00071994297,0.0015700381,0.0009613098,0.0009550624],"domain_scores_gemma":[0.9976585,0.00022238384,0.00031206844,0.0012987053,0.00010906572,0.0003993085],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025165078,0.00072696235,0.00055566843,0.00026549285,0.0003695028,0.00020939157,0.001120896,0.00031059812,0.0017451374],"category_scores_gemma":[0.0004089962,0.00063390576,0.00017370924,0.0009689256,0.00042945563,0.000317993,0.0003196991,0.00048687507,0.00043931624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007957297,0.00043577515,0.0015229501,0.000013119217,0.000012528577,0.00022335176,0.0005053678,0.0000225519,0.9925612,0.00003604522,0.0024835316,0.0013878228],"study_design_scores_gemma":[0.0032011638,0.0008516746,0.0017980584,0.000064687716,0.000011432694,0.000016776892,0.00009923036,0.0005011967,0.98808134,0.00015988371,0.004483732,0.00073084334],"about_ca_topic_score_codex":0.00010247883,"about_ca_topic_score_gemma":0.000022915921,"teacher_disagreement_score":0.004479906,"about_ca_system_score_codex":0.000093985196,"about_ca_system_score_gemma":0.00018355927,"threshold_uncertainty_score":0.9996112},"labels":[],"label_agreement":null},{"id":"W2801778180","doi":"10.1016/j.omtn.2018.04.004","title":"Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Conjugate; Glioblastoma; Oligonucleotide; Antibody; Stem cell; Gene; Cancer research; Molecular biology; Chemistry; Biology; Cell biology; Immunology; Biochemistry; Mathematics","score_opus":0.011223078158865986,"score_gpt":0.2637578287517278,"score_spread":0.25253475059286185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801778180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934501,0.0022818048,0.0009441228,0.0005202675,0.00039673102,0.0007174034,0.000029169842,0.00013399428,0.0015263857],"genre_scores_gemma":[0.9929907,0.001333596,0.0019645472,0.0026405794,0.0002469976,0.000018759803,0.000014815869,0.00012899413,0.0006610169],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975029,0.00013266866,0.00052845303,0.0006861126,0.00044521858,0.00070463365],"domain_scores_gemma":[0.9984804,0.000025186742,0.00014578179,0.0008855372,0.00016857254,0.00029453525],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033283318,0.00043130314,0.0006979097,0.00029787014,0.00010359344,0.00006843403,0.00024037843,0.00018300279,0.0007778229],"category_scores_gemma":[0.00000742087,0.00038492453,0.0002915698,0.00062163925,0.00033793662,0.00010189852,0.0000902857,0.00025548897,0.00056999957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012743918,0.00024117347,0.000994916,0.000038832077,0.0002145953,0.00085452135,0.0006880046,0.000013645048,0.9690578,0.00009272549,0.00028777838,0.026241638],"study_design_scores_gemma":[0.004665351,0.001260776,0.002373384,0.00012756429,0.00008092965,0.00017318218,0.00011600928,0.00020496744,0.94344485,0.00007224596,0.047085974,0.00039477885],"about_ca_topic_score_codex":0.00013676418,"about_ca_topic_score_gemma":0.00003402368,"teacher_disagreement_score":0.046798196,"about_ca_system_score_codex":0.00010996456,"about_ca_system_score_gemma":0.00009576704,"threshold_uncertainty_score":0.9998603},"labels":[],"label_agreement":null},{"id":"W2802473049","doi":"10.1016/j.omtn.2018.04.017","title":"Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Natur og Univers, Det Frie Forskningsråd; Stanford Maternal and Child Health Research Institute; Sundhed og Sygdom, Det Frie Forskningsråd; Amon G. Carter Foundation; Children's Health Research Institute; California Institute for Regenerative Medicine","keywords":"Biology; Progenitor cell; Haematopoiesis; Electroporation; Genome editing; Stem cell; Cell biology; Transduction (biophysics); Population; Molecular biology; CRISPR; Genetics; Gene; Medicine","score_opus":0.01246488081359751,"score_gpt":0.2931785660832801,"score_spread":0.28071368526968254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802473049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9447682,0.0024198862,0.051919907,0.000038181817,0.00020057452,0.00051868317,0.000006802712,0.000046375324,0.00008139267],"genre_scores_gemma":[0.98245364,0.000058368227,0.016443714,0.0001790853,0.0005192401,0.000061081875,0.000038638536,0.000102370876,0.0001438411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985007,0.000041665848,0.00034393932,0.00054477586,0.00014670166,0.0004222386],"domain_scores_gemma":[0.99924093,0.000008812623,0.00011147352,0.00041101885,0.000110178065,0.00011759598],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002622856,0.00027565542,0.00022316801,0.00004936863,0.00028731997,0.00006709826,0.00018747256,0.00017505324,0.000009658954],"category_scores_gemma":[0.000019186167,0.00027971683,0.00013111629,0.00007938053,0.000094061565,0.000005352461,0.00010849455,0.00008531226,0.0000031416719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037487527,0.000025273888,0.0004598602,0.00004408722,0.00007812533,0.0000071830004,0.0003411327,0.00006213321,0.9940829,0.00003544709,0.00009346611,0.004732902],"study_design_scores_gemma":[0.0007582918,0.0004867545,0.00016126016,0.000022688922,0.00002380388,0.000040203486,0.0001496077,0.00048682536,0.9894814,0.00005717004,0.007983457,0.00034857492],"about_ca_topic_score_codex":0.000007853792,"about_ca_topic_score_gemma":0.0000021953247,"teacher_disagreement_score":0.037685465,"about_ca_system_score_codex":0.000016168906,"about_ca_system_score_gemma":0.000022128621,"threshold_uncertainty_score":0.9999655},"labels":[],"label_agreement":null},{"id":"W2809774355","doi":"10.1016/j.omtn.2018.05.014","title":"Spliceosome-Mediated Pre-mRNA trans-Splicing Can Repair CEP290 mRNA","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Paul MacKall and Evanina Bell MacKall Trust; National Eye Institute; James N. Kirby Foundation; University of Pennsylvania; Research to Prevent Blindness; F. M. Kirby Foundation; Foundation Fighting Blindness","keywords":"Retinitis pigmentosa; Biology; Gene; Genome editing; RNA splicing; Genetic enhancement; Genetics; RPE65; CRISPR; RNA","score_opus":0.006731057574415501,"score_gpt":0.2328994004170985,"score_spread":0.226168342842683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809774355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98981607,0.0014158275,0.0024392693,0.0006217774,0.0002414477,0.0004451008,0.000014624346,0.0001469994,0.0048588864],"genre_scores_gemma":[0.99313015,0.00090515526,0.0015225984,0.0027759697,0.00025478823,0.000046375797,0.00021878265,0.00010590478,0.0010402757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99786,0.00011300092,0.00037659562,0.0007190408,0.00032931592,0.0006020219],"domain_scores_gemma":[0.99881715,0.000010192086,0.000113108,0.00070650666,0.00014878222,0.00020424873],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024251388,0.00040177084,0.0002791109,0.00009972207,0.00021713467,0.000053962933,0.00045242134,0.00030032475,0.00019933324],"category_scores_gemma":[0.00004510552,0.0003829421,0.0002859391,0.00029717849,0.0002565311,0.000009048669,0.00008624201,0.0001665091,0.00007256531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042629146,0.0000989794,0.007516644,0.00001538497,0.00022563024,0.000021794796,0.00047633314,0.00000782258,0.9840245,0.000064557426,0.0017550745,0.0053669866],"study_design_scores_gemma":[0.0025953806,0.0012868668,0.022230498,0.000039618484,0.000037845697,0.000028900598,0.0001512209,0.00013335091,0.71528983,0.00024187395,0.2570611,0.0009034895],"about_ca_topic_score_codex":0.000066831446,"about_ca_topic_score_gemma":0.00005651063,"teacher_disagreement_score":0.26873463,"about_ca_system_score_codex":0.000030213172,"about_ca_system_score_gemma":0.00012223222,"threshold_uncertainty_score":0.99986225},"labels":[],"label_agreement":null},{"id":"W2811096106","doi":"10.1016/j.omtn.2018.05.023","title":"A Synthetic Cross-Species CD200R1 Agonist Suppresses Inflammatory Immune Responses In Vivo","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Aptamer; PEGylation; Chemistry; Immune system; In vivo; Agonist; Cell biology; Polyethylene glycol; Receptor; Biology; Immunology; Molecular biology; Biochemistry","score_opus":0.009428480838944094,"score_gpt":0.27439365343460975,"score_spread":0.26496517259566565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2811096106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950269,0.0015616296,0.0011874682,0.00020542328,0.000094839554,0.00024414112,0.000031910582,0.00010647373,0.0015412136],"genre_scores_gemma":[0.9946248,0.00087968144,0.0020061322,0.0005521656,0.00018610684,0.000027347398,0.000032444103,0.00007257699,0.0016187258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99790096,0.00022348968,0.00045934782,0.00067149475,0.00025909266,0.00048561083],"domain_scores_gemma":[0.99854785,0.000022808124,0.00015278572,0.000991749,0.000197921,0.00008688024],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039888025,0.00036679575,0.00033597014,0.0001740143,0.00020411766,0.00012077681,0.00045856982,0.0003075422,0.00006566623],"category_scores_gemma":[0.00015968869,0.00032937244,0.00024699973,0.00023390072,0.00089914544,0.0000128320635,0.0001701093,0.00016582126,0.000018124285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076770637,0.000104495746,0.0037004713,0.000008372604,0.00008685626,0.00005019746,0.000078407196,0.0000042307297,0.99311286,0.00008766723,0.0002024952,0.001796231],"study_design_scores_gemma":[0.00063813874,0.0004676533,0.0054986887,0.000035911733,0.000012429517,0.00003128211,0.00005233747,0.000019189281,0.90358126,0.00017597538,0.08909848,0.00038863363],"about_ca_topic_score_codex":0.000026059271,"about_ca_topic_score_gemma":0.00005959582,"teacher_disagreement_score":0.08953159,"about_ca_system_score_codex":0.000039948496,"about_ca_system_score_gemma":0.00007809601,"threshold_uncertainty_score":0.99991584},"labels":[],"label_agreement":null},{"id":"W2883897094","doi":"10.1016/j.omtn.2018.07.010","title":"Splice-Modulating Oligonucleotide QR-110 Restores CEP290 mRNA and Function in Human c.2991+1655A>G LCA10 Models","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Foundation Fighting Blindness; Fight for Sight UK; ProQR Therapeutics; Retina UK; Moorfields Eye Charity; Wellcome Trust","keywords":"Exon; Biology; Mutation; Messenger RNA; Molecular biology; Retinal; Wild type; Cell biology; RNA splicing; Genetics; RNA; Mutant; Gene; Biochemistry","score_opus":0.011659525933646843,"score_gpt":0.2468154670389673,"score_spread":0.23515594110532048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883897094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883633,0.0014904664,0.003042272,0.00017223218,0.00013679171,0.0003121217,0.0000027509377,0.00004395288,0.006436062],"genre_scores_gemma":[0.99646616,0.00051096396,0.0014306653,0.0009412558,0.00017661601,0.000028001898,0.00007471727,0.000078066376,0.00029358035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998179,0.00010650975,0.00035691576,0.00065996015,0.00024572833,0.00045188869],"domain_scores_gemma":[0.9991978,0.0000070564765,0.00011501131,0.00046585538,0.00009623323,0.00011805641],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029057518,0.00033075977,0.0002440228,0.00013877923,0.00022928629,0.000060222937,0.00025530378,0.00025196694,0.000051843945],"category_scores_gemma":[0.000025718298,0.00033170392,0.00010223659,0.0002035855,0.00022797547,0.000023953113,0.00014712957,0.00015535018,0.000016455771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031678355,0.00007198309,0.010639137,0.000013687343,0.00007296798,0.000009189534,0.00031107623,0.00013482606,0.97735184,0.00082618254,0.0004081006,0.009844223],"study_design_scores_gemma":[0.0072269966,0.0030770695,0.14653508,0.00016510063,0.00006232838,0.00004005598,0.0005998353,0.0034168288,0.74676174,0.016681828,0.0732544,0.002178747],"about_ca_topic_score_codex":0.00009898055,"about_ca_topic_score_gemma":0.000084631356,"teacher_disagreement_score":0.23059012,"about_ca_system_score_codex":0.000027958675,"about_ca_system_score_gemma":0.0000442209,"threshold_uncertainty_score":0.9999135},"labels":[],"label_agreement":null},{"id":"W2886710034","doi":"10.1016/j.omtn.2018.07.013","title":"Combined Therapy in Cancer: The Non-coding Approach","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Terry Fox Foundation","keywords":"microRNA; Disease; sort; Function (biology); Coding (social sciences); Cancer; Computational biology; Medicine; Bioinformatics; Biology; Gene; Computer science; Genetics; Internal medicine; Information retrieval; Sociology","score_opus":0.013425108015741271,"score_gpt":0.2610094918277861,"score_spread":0.24758438381204484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886710034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892261,0.0020507006,0.0060025426,0.00040392106,0.00015672213,0.0006047426,0.000006656733,0.000024080968,0.0015245206],"genre_scores_gemma":[0.9962507,0.0009817131,0.0004891196,0.0016232212,0.00027467005,0.00012734764,0.00005912604,0.00006589581,0.00012822956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860615,0.00014360875,0.00023741653,0.00045628092,0.00020127594,0.00035526857],"domain_scores_gemma":[0.99902874,0.000006617222,0.00009659967,0.00070581055,0.00009441681,0.00006783265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027158475,0.00024733774,0.00017815716,0.000062644074,0.00014577266,0.00005221452,0.00048206386,0.00017699316,0.000084246734],"category_scores_gemma":[0.000013707599,0.00018848982,0.00013644775,0.00026601847,0.0002357539,0.0000066739494,0.000085009306,0.00012410808,0.00001740763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003423197,0.00014038358,0.0026667435,0.000005223316,0.00009871575,0.000002950002,0.00023014286,0.00007251409,0.9823894,0.00013215869,0.0005765578,0.013342886],"study_design_scores_gemma":[0.0027847209,0.0005668241,0.027699096,0.000019585023,0.000009720612,0.0000060840466,0.000073745236,0.0013062074,0.94474477,0.0002310705,0.02217843,0.0003797484],"about_ca_topic_score_codex":0.00006528726,"about_ca_topic_score_gemma":0.000009698965,"teacher_disagreement_score":0.03764464,"about_ca_system_score_codex":0.000040589694,"about_ca_system_score_gemma":0.00008063707,"threshold_uncertainty_score":0.7686392},"labels":[],"label_agreement":null},{"id":"W2888859121","doi":"10.1016/j.omtn.2018.08.018","title":"Protecting Pax6 3′ UTR from MicroRNA-7 Partially Restores PAX6 in Islets from an Aniridia Mouse Model","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; National Science Council; Alexander and Margaret Stewart Trust","keywords":"PAX6; Aniridia; Haploinsufficiency; Biology; microRNA; Cancer research; Pancreatic islets; Cell biology; Islet; Endocrinology; Genetics; Gene; Phenotype; Diabetes mellitus; Transcription factor","score_opus":0.01423286193013028,"score_gpt":0.26230417343412205,"score_spread":0.24807131150399175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888859121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98647606,0.0010938894,0.011170326,0.00019410202,0.00013170822,0.0006245476,0.00013485456,0.00007222079,0.00010228707],"genre_scores_gemma":[0.9905792,0.0000945881,0.006991132,0.0010729877,0.00048007607,0.0000762365,0.0005044498,0.00014071111,0.000060614682],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975022,0.00030835424,0.00044549615,0.0009600006,0.00028036462,0.00050359487],"domain_scores_gemma":[0.9983163,0.000011105541,0.00019070822,0.001152838,0.00014074461,0.00018829019],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027581348,0.0004024008,0.00029299152,0.00008858936,0.0001691031,0.0001007588,0.00054271554,0.00040531537,0.00010182269],"category_scores_gemma":[0.000076998964,0.00042112367,0.00015906255,0.0001508186,0.0001984924,0.0000257875,0.0001532335,0.00023153341,0.000045014913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005739047,0.00019080457,0.0023458507,0.0000043042387,0.00010863638,0.000017675351,0.00044891593,0.00044800306,0.9916626,0.000015971,0.00021596727,0.0039673443],"study_design_scores_gemma":[0.0015886918,0.00031593765,0.0055803023,0.00002977566,0.000020144229,0.0000020446084,0.00005438373,0.004778012,0.98281354,0.0009702135,0.003338189,0.0005087704],"about_ca_topic_score_codex":0.0005638162,"about_ca_topic_score_gemma":0.00028188515,"teacher_disagreement_score":0.008849087,"about_ca_system_score_codex":0.00006680369,"about_ca_system_score_gemma":0.00014170629,"threshold_uncertainty_score":0.99982405},"labels":[],"label_agreement":null},{"id":"W2889642654","doi":"10.1016/j.omtn.2018.09.003","title":"HIV Entry and Its Inhibition by Bifunctional Antiviral Proteins","year":2018,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Foundation for AIDS Research","keywords":"Fusion protein; Linker; Entry inhibitor; Bifunctional; Viral entry; Lipid bilayer fusion; Potency; Human immunodeficiency virus (HIV); Biology; Plasma protein binding; Computational biology; Cell biology; Chemistry; Biochemistry; Virology; Virus; In vitro; Recombinant DNA; Viral replication; Computer science; Gene","score_opus":0.019214135639017176,"score_gpt":0.27691178832305224,"score_spread":0.25769765268403505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889642654","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0035582518,0.99315333,0.000097599725,0.000078768884,0.00017816342,0.0013389192,0.0006319657,0.000077655255,0.00088534754],"genre_scores_gemma":[0.0016845742,0.9900541,0.00003889077,0.00009970684,0.000064816886,0.00030690886,0.003967277,0.00007446696,0.003709313],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979678,0.00047656865,0.00033958312,0.0006138823,0.00009884631,0.000503326],"domain_scores_gemma":[0.99937457,0.000035067176,0.00015135258,0.00031964283,0.000064206586,0.000055168475],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00017464976,0.00048107034,0.00079094537,0.00016494255,0.00023877554,0.000045388195,0.00017386352,0.00062508497,0.0009816334],"category_scores_gemma":[0.000020872656,0.0003631904,0.0003131047,0.00017538802,0.0002467918,0.0000755688,0.00010681665,0.00047282525,0.005021731],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020214147,0.00055944314,0.00001710066,0.0010726259,0.0022325087,0.00012388788,0.00006780118,1.0376583e-8,0.02968757,0.000279412,0.023762863,0.9419946],"study_design_scores_gemma":[0.0013645792,0.0005586005,0.000007080474,0.00086438423,0.00012022171,0.0001259544,0.0000034667303,1.7113489e-7,0.008690469,0.00003340292,0.98790926,0.00032240027],"about_ca_topic_score_codex":0.0000062251825,"about_ca_topic_score_gemma":4.5470023e-7,"teacher_disagreement_score":0.96414644,"about_ca_system_score_codex":0.000087018125,"about_ca_system_score_gemma":0.00014808035,"threshold_uncertainty_score":0.99993163},"labels":[],"label_agreement":null},{"id":"W2894088295","doi":"10.1016/j.omtn.2018.09.018","title":"Genetic Strategies for HIV Treatment and Prevention","year":2018,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Foundation for AIDS Research","keywords":"Biology; Secretion; Cytotoxic T cell; Haematopoiesis; Virology; Genetic enhancement; Cell biology; Viral replication; Virus; Immunology; Gene; Stem cell; In vitro; Genetics","score_opus":0.04358200410814942,"score_gpt":0.35786492369172024,"score_spread":0.3142829195835708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894088295","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013950812,0.9795192,0.0037436376,0.00002672155,0.000102077756,0.0023623924,0.000100614205,0.000032996828,0.0001615417],"genre_scores_gemma":[0.00035319515,0.99461544,0.001743687,0.00009533907,0.00045405954,0.00090540125,0.00056245556,0.00022799773,0.0010424153],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974721,0.00035084094,0.00046435458,0.0009790465,0.00019184765,0.0005417889],"domain_scores_gemma":[0.9985388,0.000021086991,0.00021282806,0.0009583799,0.000113240334,0.00015569518],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002501345,0.00068852556,0.000886499,0.00014289447,0.00016173052,0.0001519021,0.00043902206,0.00057097315,0.000060883263],"category_scores_gemma":[0.000013256502,0.00056592276,0.00070392754,0.00014198823,0.00022560186,0.000006032294,0.00009782797,0.00012263942,0.000041686922],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056379114,0.0001297944,0.0000018842594,0.00083028426,0.001068504,0.000008390231,0.00004060775,0.000002781446,0.013133038,0.00003864851,0.0005229697,0.9836593],"study_design_scores_gemma":[0.0014070764,0.0104786735,0.0000017067827,0.00037663602,0.00023749484,0.00003937745,0.000020942054,0.000007906468,0.006380005,0.00049119076,0.9799839,0.0005750707],"about_ca_topic_score_codex":0.000004445269,"about_ca_topic_score_gemma":0.000018095703,"teacher_disagreement_score":0.98308426,"about_ca_system_score_codex":0.00007573372,"about_ca_system_score_gemma":0.0005701043,"threshold_uncertainty_score":0.9996792},"labels":[],"label_agreement":null},{"id":"W2898055118","doi":"10.1016/j.omtn.2018.10.004","title":"Identification of Novel Antisense-Mediated Exon Skipping Targets in DYSF for Therapeutic Treatment of Dysferlinopathy","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Ministry of Advanced Education and Technology; Canada Foundation for Innovation; BC Children’s Hospital Foundation; BC Children's Hospital; Muscular Dystrophy Canada; Children's Hospital Foundation; University of Alberta; Women and Children's Health Research Institute; Rare Disease Foundation; Faculty of Medicine and Dentistry, University of Alberta; Alberta Innovates - Health Solutions; Ministry of Advanced Education, Government of Alberta; Children's Health Research Institute","keywords":"Dysferlin; Exon; Exon skipping; Biology; Genetics; Mutation; Myopathy; Mutant; Duchenne muscular dystrophy; Dystrophin; Molecular biology; Gene; Alternative splicing","score_opus":0.016235563305672645,"score_gpt":0.2684109666541969,"score_spread":0.25217540334852423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898055118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94208837,0.004472226,0.05260883,0.00006233062,0.00012247397,0.00052355725,0.00004725951,0.000011156361,0.000063809144],"genre_scores_gemma":[0.99771893,0.0011538672,0.00056734064,0.000112761714,0.00009063455,0.000054679356,0.00017298794,0.000047066824,0.000081759994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870795,0.00004265244,0.0004730147,0.0003808295,0.00014729556,0.0002482343],"domain_scores_gemma":[0.99905235,0.000016020247,0.00022905273,0.00042461834,0.00023433157,0.000043645712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018925825,0.00021136897,0.00028892036,0.00010844259,0.00004550719,0.000012100445,0.0001840586,0.00017871738,0.000012631538],"category_scores_gemma":[0.000029989687,0.00019702608,0.00016551369,0.00019271564,0.00016574339,0.000006340018,0.000022677783,0.000033378208,0.0000027499489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040620877,0.00059232546,0.00076376076,0.000038981092,0.00012199732,0.0000021739384,0.00036358298,0.000020122254,0.9871703,0.00008390692,0.0000056642652,0.010430983],"study_design_scores_gemma":[0.0028610034,0.0015748102,0.0014786253,0.000019947312,0.000025699821,0.0000058774476,0.00009390824,0.00061369,0.98943436,0.000115910996,0.0035856827,0.000190464],"about_ca_topic_score_codex":0.000020489015,"about_ca_topic_score_gemma":0.000014179546,"teacher_disagreement_score":0.055630542,"about_ca_system_score_codex":0.0000232947,"about_ca_system_score_gemma":0.00007591868,"threshold_uncertainty_score":0.803449},"labels":[],"label_agreement":null},{"id":"W2899342278","doi":"10.1016/j.omtn.2018.10.015","title":"Overcoming the Undesirable CRISPR-Cas9 Expression in Gene Correction","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"Cystic Fibrosis Canada; Canadian Institutes of Health Research; Cystic Fibrosis Foundation Therapeutics","keywords":"CRISPR; Gene; Computational biology; Expression (computer science); Genetics; Gene expression; Biology; Computer science; Programming language","score_opus":0.009627486999189975,"score_gpt":0.28074911113221446,"score_spread":0.2711216241330245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899342278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89949566,0.0018033116,0.09670167,0.000115605915,0.00054940506,0.00021169039,0.0000016271196,0.000025205858,0.0010958047],"genre_scores_gemma":[0.99696815,0.00035251104,0.0013003838,0.00064078794,0.00027785552,0.000024643381,0.00001625019,0.000047926653,0.00037146188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892926,0.00008143411,0.00019073777,0.00034435655,0.00015070551,0.0003035189],"domain_scores_gemma":[0.9993312,0.000010018842,0.000044443215,0.0005115185,0.000049898652,0.000052959967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022897377,0.00018815261,0.00012523758,0.000054038297,0.00013217393,0.000040464816,0.00025557296,0.00015241154,0.00006338041],"category_scores_gemma":[0.00003220515,0.00015083703,0.00008916581,0.00016521975,0.000085460946,0.00000538581,0.00008711577,0.00013472348,0.000022300623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009099263,0.000035034693,0.00083486404,0.0000026351247,0.000020153533,0.0000050841654,0.00015393183,0.0005316397,0.99142265,0.00001276577,0.00081823516,0.006071985],"study_design_scores_gemma":[0.00061635574,0.00023877255,0.0030140972,0.000017716915,0.0000051505012,0.000020763258,0.00008381781,0.0009112332,0.96154267,0.000076526485,0.033278294,0.00019459694],"about_ca_topic_score_codex":0.000030564424,"about_ca_topic_score_gemma":0.000017611792,"teacher_disagreement_score":0.0974725,"about_ca_system_score_codex":0.000024670182,"about_ca_system_score_gemma":0.00002732262,"threshold_uncertainty_score":0.61509556},"labels":[],"label_agreement":null},{"id":"W2911471940","doi":"10.1016/j.omtn.2019.02.003","title":"RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institut National de la Recherche Scientifique; Concordia University; Centre Hospitalier de l’Université de Montréal; McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Association","keywords":"Oculopharyngeal muscular dystrophy; Gene knockdown; RNA; microRNA; Biology; Muscular dystrophy; Messenger RNA; Molecular biology; Cancer research; Genetics; Gene","score_opus":0.010568683740473301,"score_gpt":0.24859427182071692,"score_spread":0.23802558808024363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911471940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868634,0.0077604186,0.002817302,0.00040626843,0.00013263577,0.0008056736,0.000012811326,0.00004604408,0.001155442],"genre_scores_gemma":[0.9943192,0.0016009407,0.0010786711,0.0019433342,0.00008640078,0.000057671998,0.000086110864,0.00009803032,0.0007296548],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99758446,0.00020792495,0.00031153834,0.00080658117,0.00044973847,0.00063974474],"domain_scores_gemma":[0.9986997,0.0000120266795,0.00008147722,0.0008688954,0.00009741163,0.00024043494],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038448014,0.0003909889,0.00034328274,0.00011276744,0.0001602594,0.000104941624,0.0003834692,0.00022900099,0.00022699664],"category_scores_gemma":[0.000015489553,0.0003477535,0.00027238918,0.0001720803,0.00012822587,0.000013376537,0.0000695484,0.00019331387,0.00003596256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011437323,0.00011169206,0.0019341839,0.000025850499,0.00019881065,0.000029810071,0.000058128593,0.000066423294,0.9769766,0.000087340006,0.00013479507,0.019232666],"study_design_scores_gemma":[0.006306488,0.0024941587,0.002344272,0.00003415982,0.000013078283,0.000016265043,0.00009483678,0.00090186775,0.91429013,0.000045472712,0.07293645,0.00052279024],"about_ca_topic_score_codex":0.000043643697,"about_ca_topic_score_gemma":0.0000027787623,"teacher_disagreement_score":0.07280166,"about_ca_system_score_codex":0.000031820677,"about_ca_system_score_gemma":0.000101448204,"threshold_uncertainty_score":0.9998974},"labels":[],"label_agreement":null},{"id":"W2914795517","doi":"10.1016/j.omtn.2019.01.008","title":"Scavenger Receptor Class A1 Mediates Uptake of Morpholino Antisense Oligonucleotide into Dystrophic Skeletal Muscle","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Japan Society for the Promotion of Science; National Center of Neurology and Psychiatry; Japan Agency for Medical Research and Development","keywords":"Morpholino; Myogenesis; Exon skipping; Duchenne muscular dystrophy; Chemistry; Dystrophin; mdx mouse; Skeletal muscle; Scavenger receptor; Downregulation and upregulation; Gene knockdown; Cell biology; Exon; Endocytosis; Molecular biology; Myocyte; Receptor; Biology; Biochemistry; Endocrinology; Apoptosis; Genetics; Lipoprotein; Gene","score_opus":0.005493664258155044,"score_gpt":0.22226595706819996,"score_spread":0.21677229281004493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914795517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954228,0.002312028,0.00021225889,0.00026259647,0.000391139,0.00040074714,0.00002659047,0.000039138606,0.0009326935],"genre_scores_gemma":[0.99616325,0.0010181611,0.0013240962,0.0008619032,0.00013268835,0.000022448363,0.00022006335,0.000091879534,0.0001654975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980062,0.00016710897,0.00044415472,0.0006618388,0.0002533941,0.00046729483],"domain_scores_gemma":[0.99862164,0.000016456832,0.00019989745,0.0008882151,0.00013024466,0.00014352456],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022003375,0.0003723034,0.0004190753,0.00009503839,0.00008593549,0.000018750045,0.00045880457,0.00038048244,0.0005036854],"category_scores_gemma":[0.000046434026,0.0003563752,0.00034753405,0.00018632297,0.00029455742,0.000012601378,0.00014935757,0.00021354372,0.00022585117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002875202,0.0001788059,0.0011822697,0.000036722173,0.00019891198,0.000008605464,0.000116020885,0.00015517406,0.9870922,0.00027649687,0.0002922718,0.010174998],"study_design_scores_gemma":[0.0032729728,0.0015277985,0.024519186,0.00003902817,0.00003737618,0.000012075929,0.00020175756,0.00016535685,0.9096122,0.0006837549,0.059194975,0.00073351053],"about_ca_topic_score_codex":0.000041610332,"about_ca_topic_score_gemma":0.000005567041,"teacher_disagreement_score":0.077479996,"about_ca_system_score_codex":0.000016056641,"about_ca_system_score_gemma":0.000088210225,"threshold_uncertainty_score":0.99988884},"labels":[],"label_agreement":null},{"id":"W2924788224","doi":"10.1016/j.omtn.2019.03.003","title":"Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Bill and Melinda Gates Foundation","keywords":"Virology; Neutralization; Antibody; Vaccination; Virus; Biology; Nucleoside; Titer; Immune system; Immunology; Neutralizing antibody; Medicine","score_opus":0.00891346113893823,"score_gpt":0.23892258542488418,"score_spread":0.23000912428594594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924788224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966605,0.0016956276,0.000079705336,0.0003065028,0.00008673777,0.00045429685,0.00004529252,0.00003104233,0.0006403103],"genre_scores_gemma":[0.99802005,0.0009608181,0.000049522783,0.00013355014,0.000006074855,0.000020936233,0.00026080423,0.000024209274,0.0005240405],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901986,0.00015669414,0.00023062108,0.00026643398,0.00004989405,0.00027651904],"domain_scores_gemma":[0.99956393,0.000026921392,0.000076098186,0.00026332005,0.00004362399,0.000026100404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011670357,0.00016326654,0.00028548492,0.00014932331,0.000037812253,0.000013604169,0.00013970549,0.00015696773,0.0004508348],"category_scores_gemma":[0.000011555096,0.00013695264,0.00005743683,0.00013471783,0.00006422907,0.00008160183,0.000049172548,0.00014029285,0.00038086085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004239788,0.00014378775,0.031840023,0.000016500595,0.00013195744,0.0000155379,0.00036892272,0.0000015233841,0.9519382,0.00032945987,0.000018338633,0.014771777],"study_design_scores_gemma":[0.0046552345,0.00041966265,0.20296034,0.00004104051,0.0000090835665,0.000017548133,0.000041582825,0.000013656879,0.7866968,0.00012006072,0.0048642782,0.00016070038],"about_ca_topic_score_codex":0.00005799688,"about_ca_topic_score_gemma":0.000005086236,"teacher_disagreement_score":0.17112032,"about_ca_system_score_codex":0.000022862698,"about_ca_system_score_gemma":0.000025918725,"threshold_uncertainty_score":0.5584767},"labels":[],"label_agreement":null},{"id":"W2939537473","doi":"10.1016/j.omtn.2019.04.008","title":"FOXM1-Mediated LINC-ROR Regulates the Proliferation and Sensitivity to Sorafenib in Hepatocellular Carcinoma","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Excellent Youth Foundation of Jiangsu Scientific Committee; U.S. Food and Drug Administration; Nanjing University; Government of Jiangsu Province; Institute of Genetics; National Natural Science Foundation of China","keywords":"FOXM1; Sorafenib; Hepatocellular carcinoma; Cancer research; Downregulation and upregulation; Carcinogenesis; Long non-coding RNA; Biology; Reprogramming; Medicine; Oncology; Cancer; Internal medicine; Cell cycle; Cell; Genetics; Gene","score_opus":0.00787479445985945,"score_gpt":0.23299872846687236,"score_spread":0.22512393400701292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939537473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906235,0.0014320327,0.004576426,0.0013124659,0.000121312674,0.0017226066,0.000015313482,0.00002975319,0.0001666255],"genre_scores_gemma":[0.99699914,0.00020576426,0.0003517911,0.0017550419,0.000084324725,0.00010893771,0.0001175731,0.00009234204,0.00028506745],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975723,0.00042681175,0.00030255306,0.0007598729,0.00039910074,0.000539364],"domain_scores_gemma":[0.9987339,0.00002856105,0.00007550291,0.00084819633,0.00014589977,0.00016793614],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007142536,0.0003286623,0.00028224676,0.00014823473,0.00011087114,0.00009506977,0.00022925185,0.00033053957,0.000042000236],"category_scores_gemma":[0.000100955294,0.00027910445,0.00012132888,0.0003877732,0.00009634901,0.000011359262,0.00023983917,0.00031326813,0.00007395969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004342595,0.00006427798,0.004228594,0.000015334255,0.0000651646,0.00007408278,0.0001953404,0.0003741433,0.9920371,0.00013054948,0.00008616779,0.0022949963],"study_design_scores_gemma":[0.0018455583,0.00066239625,0.0066544632,0.000025327116,0.0000106616,0.00006200548,0.00007713249,0.0069059124,0.9733195,0.00013027391,0.009908063,0.0003987229],"about_ca_topic_score_codex":0.000103987135,"about_ca_topic_score_gemma":0.000062222985,"teacher_disagreement_score":0.018717607,"about_ca_system_score_codex":0.000062789426,"about_ca_system_score_gemma":0.00013582136,"threshold_uncertainty_score":0.9999661},"labels":[],"label_agreement":null},{"id":"W2958336030","doi":"10.1016/j.omtn.2019.07.001","title":"Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health","keywords":"Human immunodeficiency virus (HIV); Dual (grammatical number); Oligonucleotide; Action (physics); Medicine; Virology; Biology; Physics; Genetics; Philosophy","score_opus":0.012377211362767974,"score_gpt":0.24734167028396403,"score_spread":0.23496445892119605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2958336030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851024,0.0013234285,0.010458263,0.00015765819,0.00017032037,0.00084142986,0.000051446565,0.000086003136,0.0018090354],"genre_scores_gemma":[0.9942557,0.00055941765,0.0037713617,0.00017917792,0.000018318684,0.000021191061,0.00013638732,0.00005258955,0.0010058566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983838,0.00021407964,0.00032568202,0.00045710205,0.00016263516,0.00045670962],"domain_scores_gemma":[0.99908847,0.000015956177,0.0001395444,0.00057018956,0.000099152574,0.000086668755],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00018556634,0.0002843261,0.00047590848,0.00021471236,0.00007999856,0.000017884302,0.0003422493,0.00023285885,0.0013720072],"category_scores_gemma":[0.000009017865,0.00024155523,0.00025504682,0.00023084163,0.00007977657,0.00008641196,0.00009160171,0.00020566187,0.002117842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00083093427,0.0007144429,0.0003814907,0.000019780375,0.001147214,0.000014178375,0.0007909149,0.00011094503,0.9822579,0.0013198965,0.00045807936,0.011954243],"study_design_scores_gemma":[0.0046624495,0.0013788643,0.0030453831,0.000019479552,0.00003230223,0.000054578446,0.00025539997,0.000022249744,0.9830285,0.00029972947,0.006971338,0.00022977669],"about_ca_topic_score_codex":0.0002587323,"about_ca_topic_score_gemma":9.897743e-7,"teacher_disagreement_score":0.011724467,"about_ca_system_score_codex":0.000045275265,"about_ca_system_score_gemma":0.00012466419,"threshold_uncertainty_score":0.99954087},"labels":[],"label_agreement":null},{"id":"W2966702973","doi":"10.1016/j.omtn.2019.08.001","title":"Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Microbial Inactivation Methods","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"Universiteit Gent; China Scholarship Council; Massachusetts Institute of Technology","keywords":"Innate immune system; Electroporation; Kinetics; Messenger RNA; Immune system; Cell biology; Chemistry; Biology; Immunology; Biochemistry; Gene; Physics","score_opus":0.006200401510674658,"score_gpt":0.24345583782442243,"score_spread":0.23725543631374776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2966702973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957232,0.0021130398,0.0015617982,0.00017076443,0.000023496044,0.00036352544,0.0000044582657,0.000008097927,0.00003161927],"genre_scores_gemma":[0.99447316,0.0007159675,0.0041797548,0.00051790354,0.000015572052,0.000018961462,0.000033685665,0.000026914675,0.000018066057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986059,0.00059496815,0.00024532792,0.00026891034,0.00012260587,0.0001622913],"domain_scores_gemma":[0.99940705,0.000044544926,0.00011945061,0.00033269706,0.0000696796,0.000026601878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000635639,0.0001529088,0.00015739938,0.00008542384,0.000028738288,0.000028256603,0.0001319598,0.00016388058,0.0000161963],"category_scores_gemma":[0.000053853502,0.00012237886,0.000041476065,0.00016069046,0.000057447465,0.000010053988,0.000071454146,0.00012511422,0.0000016013299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014942591,0.00006227831,0.0014014407,0.000014690034,0.000023359446,0.000004041225,0.0005644514,0.0000075128964,0.99514806,0.000012201437,0.000013570618,0.0012541286],"study_design_scores_gemma":[0.0010706158,0.0004895266,0.03156681,0.00001985155,0.000006164925,0.000012729905,0.00011489406,0.00007332681,0.96349406,0.000053344844,0.0029554486,0.00014320403],"about_ca_topic_score_codex":0.000012783593,"about_ca_topic_score_gemma":0.000001469355,"teacher_disagreement_score":0.03165398,"about_ca_system_score_codex":0.000015033038,"about_ca_system_score_gemma":0.000028247136,"threshold_uncertainty_score":0.4990465},"labels":[],"label_agreement":null},{"id":"W2970229575","doi":"10.1016/j.omtn.2019.08.019","title":"Studying Interactions between 2’-O-Me-Modified Inhibitors and MicroRNAs Utilizing Microscale Thermophoresis","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Field-Flow Fractionation Techniques","field":"Engineering","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"European Commission; M.S.I. Foundation","keywords":"Microscale thermophoresis; Isothermal titration calorimetry; Chemistry; Oligonucleotide; Surface plasmon resonance; Microscale chemistry; microRNA; Small molecule; Biophysics; Thermophoresis; Computational biology; Nanotechnology; Biochemistry; Biology; Materials science","score_opus":0.012721121075568498,"score_gpt":0.24184683671370025,"score_spread":0.22912571563813175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970229575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98552847,0.0008706739,0.007912984,0.00015289409,0.00035429164,0.00043476757,0.000008650356,0.00062795903,0.0041093053],"genre_scores_gemma":[0.9972179,0.00021939626,0.0019969498,0.00022457316,0.000074919466,0.00003678402,0.000012451913,0.00010121789,0.000115807496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988718,0.000054822092,0.0003026726,0.00030705976,0.00019171162,0.0002719047],"domain_scores_gemma":[0.9993865,0.000076837,0.00005815187,0.0003627547,0.000050634175,0.00006515172],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015220745,0.00025953277,0.00025562284,0.00021603903,0.000105191735,0.00010363882,0.00019514661,0.00015767914,0.00011619781],"category_scores_gemma":[0.00001124425,0.00027344734,0.000108741966,0.00022643276,0.00004378479,0.0002353578,0.000056559857,0.00036146748,0.000070625305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013230764,0.000023179666,0.0043284553,0.000020281366,0.00012671128,0.0000037437346,0.00044091893,0.000078971214,0.9749281,0.000117018484,0.00030161676,0.019617787],"study_design_scores_gemma":[0.0006293472,0.00007122688,0.007935224,0.00005749606,0.00002003637,0.000009840791,0.0002903298,0.0010808952,0.9711446,0.0003738154,0.017989777,0.00039741618],"about_ca_topic_score_codex":0.00003033114,"about_ca_topic_score_gemma":0.000003023681,"teacher_disagreement_score":0.019220369,"about_ca_system_score_codex":0.000097798285,"about_ca_system_score_gemma":0.000010448899,"threshold_uncertainty_score":0.99997175},"labels":[],"label_agreement":null},{"id":"W2977044530","doi":"10.1016/j.omtn.2019.09.017","title":"Overexpression of lncRNA EPB41L4A-AS1 Induces Metabolic Reprogramming in Trophoblast Cells and Placenta Tissue of Miscarriage","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"National Natural Science Foundation of China","keywords":"Reprogramming; Trophoblast; Miscarriage; Placenta; Cell biology; Andrology; Biology; Pregnancy; Medicine; Cell; Fetus; Genetics","score_opus":0.00686019472766756,"score_gpt":0.2542566133557578,"score_spread":0.24739641862809023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2977044530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99113256,0.0061847833,0.0014485234,0.000034546283,0.00008920038,0.00071487535,0.00002521896,0.000010346529,0.0003599215],"genre_scores_gemma":[0.996523,0.00138604,0.0016790497,0.00008046436,0.000032365067,0.000026290905,0.000035074405,0.00007456777,0.00016314242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99787086,0.00023877619,0.0004531213,0.0006345637,0.00040554945,0.00039714528],"domain_scores_gemma":[0.9987846,0.000015407724,0.00021992197,0.0007694233,0.0000990033,0.000111671485],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037562396,0.00027834772,0.00044970345,0.000188991,0.000030667772,0.000023473638,0.0003682538,0.00033370493,0.000109651846],"category_scores_gemma":[0.000030309393,0.00027156816,0.00014130454,0.00030024326,0.00013033873,0.000010708442,0.00024900422,0.00023709892,0.000006712816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050628826,0.00013350352,0.00019963713,0.00005960206,0.00011231624,0.000011111307,0.00016799642,0.00016081818,0.98449284,0.00008907333,0.000025565485,0.014041239],"study_design_scores_gemma":[0.0023447368,0.00074252236,0.0005479647,0.00011095204,0.000014220281,0.000010748357,0.0001445476,0.00006415361,0.98635316,0.000062287225,0.009356061,0.0002486435],"about_ca_topic_score_codex":0.00014158318,"about_ca_topic_score_gemma":0.0000060014236,"teacher_disagreement_score":0.013792596,"about_ca_system_score_codex":0.000020528025,"about_ca_system_score_gemma":0.000084928535,"threshold_uncertainty_score":0.99997365},"labels":[],"label_agreement":null},{"id":"W2977235223","doi":"10.1016/j.omtn.2019.09.019","title":"Computational Methods for Identifying Similar Diseases","year":2019,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China; Heilongjiang Postdoctoral Science Foundation","keywords":"Similarity (geometry); Pairwise comparison; Disease; Computational biology; Identification (biology); Phenotype; Benchmark (surveying); Function (biology); Bioinformatics; Biology; Computer science; Medicine; Artificial intelligence; Genetics; Gene; Pathology","score_opus":0.05133603354306864,"score_gpt":0.38565188592715216,"score_spread":0.3343158523840835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2977235223","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000009221951,0.66322124,0.3350606,0.000016081882,0.00036646408,0.0010338798,0.00014077194,0.000019483967,0.00013225582],"genre_scores_gemma":[0.000018831079,0.9269107,0.06830916,0.00067093124,0.00032775183,0.00020514366,0.0030506363,0.00017567308,0.00033116434],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978625,0.00022639016,0.0006689466,0.0006263327,0.00016889736,0.00044689068],"domain_scores_gemma":[0.9985227,0.00007740471,0.00039883336,0.0007538922,0.00011026594,0.00013690187],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038543978,0.0005869145,0.0011004229,0.00010904235,0.00013702814,0.00012995602,0.0006368038,0.00058516156,0.000040600087],"category_scores_gemma":[0.000035351117,0.0005179976,0.001234261,0.0001425697,0.00008522545,0.000006095882,0.00020145674,0.00021605122,0.00004811662],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031092633,0.000046729336,7.657419e-7,0.0024072917,0.00078496244,0.0000020780165,0.000016999098,0.00023717192,0.00024965365,0.00035870838,0.0015713362,0.9942932],"study_design_scores_gemma":[0.0006015887,0.00018474626,0.0000010519535,0.00053945306,0.00039024558,0.000019811761,0.00000744477,0.0008327121,0.00009363346,0.0014756004,0.995242,0.00061169063],"about_ca_topic_score_codex":9.2662515e-7,"about_ca_topic_score_gemma":1.555187e-7,"teacher_disagreement_score":0.99368155,"about_ca_system_score_codex":0.00004013536,"about_ca_system_score_gemma":0.00025698447,"threshold_uncertainty_score":0.9997272},"labels":[],"label_agreement":null},{"id":"W2981314464","doi":"10.1016/j.omtn.2019.10.011","title":"A U1i RNA that Enhances HIV-1 RNA Splicing with an Elongated Recognition Domain Is an Optimal Candidate for Combination HIV-1 Gene Therapy","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Polyadenylation; RNA; RNA splicing; Long non-coding RNA; Biology; Small hairpin RNA; RNA interference; Non-coding RNA; DNA-directed RNA interference; Gene; Computational biology; Genetics","score_opus":0.01515109169023707,"score_gpt":0.24740053732790826,"score_spread":0.2322494456376712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981314464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97695446,0.00062313094,0.020762831,0.00021095111,0.00012929272,0.00094594737,0.000119012555,0.000049665756,0.00020471761],"genre_scores_gemma":[0.98945874,0.00089291844,0.0050092433,0.0018676243,0.00012245348,0.00012869017,0.0021553359,0.00010444042,0.00026054832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980642,0.00015201332,0.00027334786,0.0007965476,0.00025944313,0.00045440212],"domain_scores_gemma":[0.998751,0.000008785912,0.00019704767,0.00067202776,0.00023300534,0.00013816095],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026700014,0.00039731304,0.00030759783,0.00010516966,0.0001761404,0.00013345414,0.00040210583,0.00026058784,0.0001671404],"category_scores_gemma":[0.0000040253185,0.00034405038,0.00015252063,0.00013583293,0.00008478025,0.000060749833,0.00003573557,0.00013465452,0.000049345246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028100873,0.00021857949,0.00042198304,0.000010302063,0.00022437036,0.000007921395,0.0005483152,0.0000819644,0.97523147,0.000010421822,0.00011221055,0.020322397],"study_design_scores_gemma":[0.0041858694,0.005227908,0.0006362395,0.000038155304,0.000021827047,0.000021197977,0.0003883641,0.0008205624,0.9857082,0.00021944685,0.0021790476,0.0005531858],"about_ca_topic_score_codex":0.000048933485,"about_ca_topic_score_gemma":0.000015800675,"teacher_disagreement_score":0.01976921,"about_ca_system_score_codex":0.000032976488,"about_ca_system_score_gemma":0.00008479861,"threshold_uncertainty_score":0.9999012},"labels":[],"label_agreement":null},{"id":"W2981684899","doi":"10.1016/j.omtn.2019.10.015","title":"Characterization of a Prostate- and Prostate Cancer-Specific Circular RNA Encoded by the Androgen Receptor Gene","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Science Foundation of Zhejiang Province; Canadian Institutes of Health Research; China Scholarship Council","keywords":"Prostate cancer; Androgen receptor; Cancer research; Prostate; Circular RNA; Biology; PCA3; Alternative splicing; Long non-coding RNA; RNA; Gene; Cancer; Messenger RNA; Genetics","score_opus":0.00575544211366111,"score_gpt":0.21603463420458274,"score_spread":0.21027919209092163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981684899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98335683,0.014396112,0.0004146161,0.00026278768,0.00014768598,0.0010823513,0.00024816653,0.00002227727,0.00006919475],"genre_scores_gemma":[0.99016327,0.008112459,0.000105703286,0.00052214327,0.000059658156,0.00012217871,0.0006038635,0.00008272523,0.00022797455],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998426,0.00015013652,0.0003019586,0.0005397485,0.00027855317,0.00030358156],"domain_scores_gemma":[0.99886394,0.000006459735,0.00019972208,0.00070534373,0.0001288986,0.00009562771],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018242931,0.00027268127,0.0002487232,0.000041997413,0.00008731712,0.000055877317,0.00032741195,0.00014920915,0.00011384161],"category_scores_gemma":[0.000013103727,0.00022410348,0.00013529729,0.00017442436,0.00018241476,0.000013008805,0.0001071473,0.000102097285,0.000014269555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025568972,0.000086515116,0.007854042,0.00003178703,0.0001829862,0.0000030389572,0.00023002875,0.0000144501655,0.9815773,0.000026129144,0.00020709974,0.009530933],"study_design_scores_gemma":[0.0012318857,0.00021015637,0.002168506,0.000022714967,0.000019791501,0.000010909135,0.000049656217,0.000029256162,0.94104487,0.00003618544,0.054904424,0.0002716255],"about_ca_topic_score_codex":0.000018262459,"about_ca_topic_score_gemma":7.416097e-7,"teacher_disagreement_score":0.054697324,"about_ca_system_score_codex":0.000025712166,"about_ca_system_score_gemma":0.00007496702,"threshold_uncertainty_score":0.9138675},"labels":[],"label_agreement":null},{"id":"W2983464809","doi":"10.1016/j.omtn.2019.10.042","title":"Nucleic Acid Aptamers for Molecular Therapy of Epilepsy and Blood-Brain Barrier Damages","year":2019,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Epilepsy; Blood–brain barrier; Epileptogenesis; Aptamer; Nucleic acid; Pharmacology; Medicine; Neuroscience; Biology; Biochemistry; Central nervous system; Genetics","score_opus":0.020457462097481685,"score_gpt":0.3104488103809664,"score_spread":0.2899913482834847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2983464809","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019306477,0.9753036,0.002576287,0.00010265113,0.00012455032,0.0020165446,0.0002861963,0.000085107735,0.00019861745],"genre_scores_gemma":[0.010817537,0.9789927,0.0074930857,0.0009642657,0.00013632451,0.0001483112,0.00073134893,0.00034204623,0.00037435791],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961171,0.00041448072,0.0009611123,0.001443499,0.00038192942,0.0006818619],"domain_scores_gemma":[0.9970393,0.00006732461,0.0007770598,0.0016727031,0.0002417447,0.00020187271],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005552714,0.0011220988,0.002194991,0.00031799971,0.0001327496,0.00007813333,0.0007982269,0.0011431476,0.000015725185],"category_scores_gemma":[0.00011956996,0.0009267452,0.0016451385,0.00038481425,0.00049635966,0.000012488713,0.00022510672,0.00037940362,0.000005808542],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010930175,0.000119399214,0.000008768116,0.00081600004,0.0015723394,0.000016687321,0.000020290014,5.599032e-7,0.50041974,0.00009405347,0.00022731577,0.49659556],"study_design_scores_gemma":[0.0010239771,0.0010928124,0.0000022246775,0.00065177336,0.0004778327,0.0000439021,0.000021193906,0.0000065440736,0.333784,0.00012355688,0.6619307,0.00084147137],"about_ca_topic_score_codex":0.0000061271367,"about_ca_topic_score_gemma":0.0000010435084,"teacher_disagreement_score":0.66170335,"about_ca_system_score_codex":0.000029566176,"about_ca_system_score_gemma":0.00020102291,"threshold_uncertainty_score":0.9993183},"labels":[],"label_agreement":null},{"id":"W2991374012","doi":"10.1016/j.omtn.2019.11.029","title":"Plk2 Regulated by miR-128 Induces Ischemia-Reperfusion Injury in Cardiac Cells","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Gene silencing; Small interfering RNA; Apoptosis; microRNA; Cancer research; Reperfusion injury; Oxidative stress; Ischemia; Cell biology; Kinase; Programmed cell death; Medicine; Biology; Chemistry; Internal medicine; Transfection; Biochemistry; Gene","score_opus":0.003783420363644705,"score_gpt":0.21727947113709614,"score_spread":0.21349605077345143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991374012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99492055,0.0032643748,0.00009132401,0.00013042163,0.00026021557,0.0006320149,0.000047040237,0.000039993614,0.0006140573],"genre_scores_gemma":[0.997472,0.00047273547,0.000266351,0.00052273006,0.00007273838,0.00003178383,0.0004390974,0.00009559247,0.0006269797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980125,0.00019445969,0.00035852566,0.0007141574,0.00029896712,0.00042140696],"domain_scores_gemma":[0.99877423,0.0000071459376,0.00013888224,0.00087118935,0.00008126533,0.00012727443],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002616298,0.00034936066,0.00032106065,0.000099843906,0.000052506413,0.00004596052,0.0003692664,0.00046770452,0.00020197895],"category_scores_gemma":[0.000015359157,0.00035448524,0.0002250953,0.00026033848,0.00007858463,0.000013810471,0.0001465453,0.00018822766,0.000114047674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026196634,0.0001234995,0.001587581,0.000016028305,0.00008912823,0.000004761495,0.00006117497,0.00004980654,0.991118,0.000010722842,0.003353056,0.0033242742],"study_design_scores_gemma":[0.0010531411,0.00021592344,0.001072795,0.000028154189,0.000013121952,0.000001968042,0.000028175606,0.000050007795,0.9559377,0.000036776488,0.041150425,0.00041180098],"about_ca_topic_score_codex":0.00003446777,"about_ca_topic_score_gemma":8.169893e-7,"teacher_disagreement_score":0.03779737,"about_ca_system_score_codex":0.00006165089,"about_ca_system_score_gemma":0.00007886168,"threshold_uncertainty_score":0.9998907},"labels":[],"label_agreement":null},{"id":"W2998455966","doi":"10.1016/j.omtn.2019.12.021","title":"A Universal Surrogate Reporter for Efficient Enrichment of CRISPR/Cas9-Mediated Homology-Directed Repair in Mammalian Cells","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Major Science and Technology Projects of China; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; Genome editing; Homology directed repair; Computational biology; Biology; Trans-activating crRNA; DNA; Genetics; DNA repair; Gene; Nucleotide excision repair","score_opus":0.0050329950211648565,"score_gpt":0.24870616540013565,"score_spread":0.2436731703789708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2998455966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910418,0.0010228237,0.006510854,0.000073265066,0.0002843952,0.0007712344,0.000040853705,0.00005575614,0.00019904142],"genre_scores_gemma":[0.9966749,0.00010663641,0.002445447,0.00019070719,0.000029805833,0.000036254325,0.00011552264,0.000055660807,0.00034509617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984881,0.00007248385,0.00038754955,0.0005123178,0.00015977875,0.00037973147],"domain_scores_gemma":[0.9990838,0.00001946326,0.00012209277,0.00059187826,0.00010244627,0.00008029645],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028506908,0.00024202911,0.0003018387,0.00012796876,0.000023722698,0.0000069182183,0.00020464371,0.0002222987,0.00005159941],"category_scores_gemma":[0.00002701401,0.0002454158,0.00024584023,0.00019581329,0.000057109337,0.0000025418274,0.00007019733,0.000089683504,0.000008654465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032055238,0.00015313832,0.0021750827,0.000039970793,0.00011539638,0.000036319034,0.00015478517,0.0035189479,0.9926466,0.000024632556,0.00033434632,0.00048026466],"study_design_scores_gemma":[0.0027616776,0.00080848613,0.004733875,0.000021430265,0.000020878702,0.000015649268,0.00011267426,0.0029145137,0.96556866,0.0000139282165,0.022701418,0.0003267853],"about_ca_topic_score_codex":0.000040898027,"about_ca_topic_score_gemma":0.000010367253,"teacher_disagreement_score":0.02707788,"about_ca_system_score_codex":0.000033672102,"about_ca_system_score_gemma":0.00005821984,"threshold_uncertainty_score":0.9999998},"labels":[],"label_agreement":null},{"id":"W3005987282","doi":"10.1016/j.omtn.2020.02.005","title":"Targeting Ephrin Receptor Tyrosine Kinase A2 with a Selective Aptamer for Glioblastoma Stem Cells","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Joint Attosecond Science Laboratory; University of Ottawa","funders":"Fondazione Umberto Veronesi; Ministero della Salute; H2020 Marie Skłodowska-Curie Actions; Associazione Italiana per la Ricerca sul Cancro; Multiple Sclerosis Center of Atlanta","keywords":"Aptamer; Glioblastoma; Receptor tyrosine kinase; Tyrosine kinase; Ephrin; Stem cell; Cancer research; ROR1; Proto-oncogene tyrosine-protein kinase Src; Receptor; Tropomyosin receptor kinase C; Platelet-derived growth factor receptor; Cell biology; Chemistry; Biology; Kinase; Molecular biology; Biochemistry; Growth factor","score_opus":0.02216463311813383,"score_gpt":0.23600588099777414,"score_spread":0.21384124787964032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005987282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95897865,0.0003452804,0.03780432,0.0012904329,0.00012428795,0.0010414515,0.000038067996,0.00025397708,0.00012353765],"genre_scores_gemma":[0.98590267,0.000089690715,0.0016151709,0.011869778,0.0001682525,0.00011597318,0.0000023016125,0.00014458336,0.00009156276],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99757403,0.00018715083,0.00032159392,0.0008837146,0.0004454777,0.00058805005],"domain_scores_gemma":[0.9990877,0.0001372191,0.00018902429,0.00025089856,0.000100432735,0.00023472743],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013402461,0.0003789097,0.00035256447,0.0000660738,0.00027854118,0.000102342696,0.00042774706,0.00009946668,0.00011265181],"category_scores_gemma":[0.00005837337,0.0003225972,0.00016419217,0.0006424175,0.00013234593,0.00020749615,0.0000658036,0.000288808,0.000116269075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019557716,0.000082811646,0.000039086794,0.000021970021,0.000026578886,0.00007807613,0.00060707977,0.000678492,0.9909451,0.00024715616,0.00072647404,0.004591414],"study_design_scores_gemma":[0.0017432839,0.0022176737,0.000006745733,0.0000325995,0.000014611806,0.000007848725,0.000098697274,0.0027868855,0.9632623,0.00003849286,0.029389933,0.00040091385],"about_ca_topic_score_codex":0.000004070094,"about_ca_topic_score_gemma":3.5396152e-7,"teacher_disagreement_score":0.036189146,"about_ca_system_score_codex":0.000050017654,"about_ca_system_score_gemma":0.000067666355,"threshold_uncertainty_score":0.99992263},"labels":[],"label_agreement":null},{"id":"W3033123873","doi":"10.1016/j.omtn.2020.05.030","title":"CRISPR-Cas13a Inhibits HIV-1 Infection","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Peking Union Medical College; Canadian Institutes of Health Research; Chinese Academy of Medical Sciences; National Natural Science Foundation of China; Chinese Academy of Meteorological Sciences; Ministry of Science and Technology of the People's Republic of China","keywords":"CRISPR; Biology; RNA; Effector; Plasmid; Trans-activating crRNA; Virology; DNA; Gene; Cas9; Genetics; Cell biology","score_opus":0.01045312759101866,"score_gpt":0.2709161115900577,"score_spread":0.260462983999039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033123873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8556794,0.001692891,0.14011587,0.00090635096,0.00014100403,0.00020847227,0.000008682538,0.0000790169,0.0011683118],"genre_scores_gemma":[0.99475276,0.00054080744,0.0010779186,0.0030187464,0.00031500022,0.000020676945,0.00007950759,0.0000722894,0.0001222809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988465,0.00004778228,0.00020663021,0.00043704297,0.00016751523,0.00029456205],"domain_scores_gemma":[0.9993837,0.0000033713306,0.000045278284,0.00033792268,0.000055650373,0.00017408337],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007901042,0.00024294804,0.00016826879,0.000037759182,0.00007048631,0.000040938652,0.0001758898,0.00017821624,0.00009518776],"category_scores_gemma":[0.00003999738,0.00025026593,0.00016632058,0.00017377721,0.000043969063,0.000004955711,0.00009251487,0.0001452386,0.00011632283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069736656,0.000033428118,0.0014188649,0.00001249108,0.00007286186,0.000011352013,0.00015652135,0.0010308293,0.98831403,0.00005239215,0.0018351588,0.006992303],"study_design_scores_gemma":[0.00079822924,0.00035125134,0.0019676753,0.0000064623787,0.000011676801,0.0000149054185,0.000017936933,0.00033429015,0.83485097,0.000025777563,0.1613352,0.00028564606],"about_ca_topic_score_codex":0.000008654692,"about_ca_topic_score_gemma":0.000001736765,"teacher_disagreement_score":0.15950005,"about_ca_system_score_codex":0.000010952193,"about_ca_system_score_gemma":0.00002793343,"threshold_uncertainty_score":0.99999493},"labels":[],"label_agreement":null},{"id":"W3037266749","doi":"10.1016/j.omtn.2020.06.022","title":"Rapid Development of Targeting circRNAs in Cardiovascular Diseases","year":2020,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Natural Science Foundation of China","keywords":"Computational biology; Circular RNA; Bioinformatics; Biology; Disease; microRNA; Medicine; Pathology; Genetics; Gene","score_opus":0.020496287773783088,"score_gpt":0.27131620658443945,"score_spread":0.25081991881065635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3037266749","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022698836,0.995074,0.0010919465,0.000008483801,0.00018318804,0.0010679812,0.0000820914,0.000039985716,0.00018247298],"genre_scores_gemma":[0.003922321,0.99284774,0.0014034887,0.00011143499,0.00021299491,0.00023218495,0.0009968997,0.00025922334,0.00001372442],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959539,0.00054967654,0.0011593958,0.0011756878,0.00060988124,0.00055141805],"domain_scores_gemma":[0.9979493,0.000022710774,0.00039171532,0.0012818545,0.00009782266,0.00025658705],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035809763,0.000824085,0.0022918878,0.00022211768,0.00008127234,0.00004129492,0.0010333855,0.0005165343,0.000070784445],"category_scores_gemma":[0.0002123247,0.0008052497,0.0022399765,0.0005131065,0.00015987369,0.00000655833,0.00041125395,0.00032617865,0.00004039057],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004192927,0.00019714177,0.000053893273,0.0027622455,0.0025012612,0.00018552587,0.00006668253,0.00001863099,0.0035472133,0.000013419894,0.0001506649,0.9904614],"study_design_scores_gemma":[0.0007222761,0.00009055073,0.000046976715,0.0012950484,0.00044250878,0.000019222176,0.00002572484,0.0000022833383,0.0049624145,0.000014158532,0.9915685,0.00081030093],"about_ca_topic_score_codex":0.000005906446,"about_ca_topic_score_gemma":9.763442e-7,"teacher_disagreement_score":0.9914179,"about_ca_system_score_codex":0.00011203568,"about_ca_system_score_gemma":0.0008864144,"threshold_uncertainty_score":0.99943984},"labels":[],"label_agreement":null},{"id":"W3089169813","doi":"10.1016/j.omtn.2020.09.019","title":"miR-18a Contributes to Preeclampsia by Downregulating Smad2 (Full Length) and Reducing TGF-β Signaling","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"National Key Research and Development Program of China; Jiangsu Normal University; National Natural Science Foundation of China","keywords":"Downregulation and upregulation; Trophoblast; Preeclampsia; Transforming growth factor; Placenta; Andrology; Cell; Gene isoform; Phosphorylation; Cell biology; Chemistry; Biology; Gene; Medicine; Pregnancy; Genetics; Biochemistry; Fetus","score_opus":0.017829601331001164,"score_gpt":0.24929850784045365,"score_spread":0.23146890650945248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089169813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9478017,0.02669813,0.009912269,0.012722306,0.00009243779,0.0010295286,0.000024812296,0.00026575703,0.0014530795],"genre_scores_gemma":[0.98540336,0.000325888,0.005244042,0.008628144,0.00012368691,0.00006385574,0.000034608387,0.000087148364,0.00008926818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978356,0.00013624075,0.0004530643,0.0006906069,0.00034286786,0.0005416452],"domain_scores_gemma":[0.998947,0.00010807908,0.00011352572,0.00039720788,0.000098498575,0.00033563995],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027844968,0.00040133228,0.00065609923,0.000080288475,0.000281174,0.0000821783,0.0002061942,0.00018571729,0.00008024882],"category_scores_gemma":[0.00020932172,0.00036687768,0.00016728583,0.000380955,0.00013717459,0.00010325414,0.00016361903,0.00035632207,0.000027922726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071696093,0.00006326189,0.002677475,0.000111644484,0.000504163,0.00007053083,0.0031161166,0.000060518265,0.971563,0.00027440762,0.0020144542,0.018827513],"study_design_scores_gemma":[0.009440033,0.0026244756,0.0070232544,0.0014997834,0.00037576057,0.00009462072,0.0012628005,0.0021046456,0.90348315,0.0010093064,0.069816835,0.0012653572],"about_ca_topic_score_codex":0.000030134546,"about_ca_topic_score_gemma":0.0000011282734,"teacher_disagreement_score":0.06807983,"about_ca_system_score_codex":0.000051063755,"about_ca_system_score_gemma":0.000042865537,"threshold_uncertainty_score":0.99987835},"labels":[],"label_agreement":null},{"id":"W3096133357","doi":"10.1016/j.omtn.2020.10.041","title":"lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; Natural Science Foundation for Distinguished Young Scholars of Anhui Province","keywords":"Biology; Downregulation and upregulation; Long non-coding RNA; Cell cycle; Premature ovarian insufficiency; Premature ovarian failure; Cancer research; Cell biology; Internal medicine; Endocrinology; Cell; Gene; Genetics; Medicine","score_opus":0.015424892499756088,"score_gpt":0.26168070866227233,"score_spread":0.24625581616251624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3096133357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9168599,0.0021857722,0.07493419,0.0037595914,0.0000886107,0.0013019964,0.000052845615,0.000047115143,0.00076994044],"genre_scores_gemma":[0.9922916,0.00022467427,0.0032578043,0.0036862995,0.000069825444,0.00007971497,0.00022972065,0.000112272144,0.00004806071],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99709934,0.00028491652,0.00050365506,0.0009556778,0.0005102723,0.0006461627],"domain_scores_gemma":[0.99903286,0.000017009655,0.00011231384,0.0004881579,0.00009683607,0.00025280268],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003688814,0.00038526597,0.0003639817,0.00023451413,0.00009346067,0.00007550292,0.0005259166,0.00046710635,0.00010124568],"category_scores_gemma":[0.000089755056,0.000431556,0.00016126088,0.0011336785,0.000069274334,0.000018022223,0.00015177792,0.00052308734,0.000028135662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045962387,0.00015818283,0.00019342419,0.000026329271,0.000056228928,0.000035700912,0.001683574,0.00080476626,0.9878076,0.00009351649,0.00024424132,0.008436838],"study_design_scores_gemma":[0.0027846028,0.0009543544,0.00031860586,0.00009837856,0.000009027471,0.0000063789175,0.0003747069,0.0037237662,0.9772596,0.00009600476,0.013828554,0.00054606213],"about_ca_topic_score_codex":0.00008917676,"about_ca_topic_score_gemma":0.00006959515,"teacher_disagreement_score":0.0754317,"about_ca_system_score_codex":0.000121711404,"about_ca_system_score_gemma":0.0001266178,"threshold_uncertainty_score":0.9998136},"labels":[],"label_agreement":null},{"id":"W3114706432","doi":"10.1016/j.omtn.2020.12.022","title":"Efficacy, accumulation, and transcriptional profile of anti-HIV shRNAs expressed from human U6, 7SK, and H1 promoters","year":2020,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Promoter; Human immunodeficiency virus (HIV); Biology; Genetics; Computational biology; Virology; Gene; Gene expression","score_opus":0.02196704284237798,"score_gpt":0.2769143256621299,"score_spread":0.25494728281975193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3114706432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99081624,0.00084761874,0.007266319,0.0006185949,0.000011069952,0.00025851294,0.00008539454,0.00004284354,0.000053425138],"genre_scores_gemma":[0.9917654,0.00027691928,0.006870348,0.0005905255,0.000066680346,0.000005929809,0.00037511004,0.00003235414,0.000016728816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988768,0.00007769509,0.0002573014,0.00047112533,0.0001602777,0.0001567631],"domain_scores_gemma":[0.99947065,0.0000066183634,0.00011047594,0.00024519063,0.00007002771,0.000097023825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007658248,0.0002071926,0.00024883865,0.000036079586,0.000088523004,0.000030678457,0.00013524375,0.00015864578,0.000011815708],"category_scores_gemma":[0.000020724685,0.00018712279,0.000101508136,0.0000948835,0.00016990844,0.0000088940305,0.00005598072,0.000090117006,7.2669064e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014967225,0.00006318804,0.0018671285,0.00001033662,0.0001342725,0.000003488434,0.00017375342,0.000010274255,0.9949718,0.000056046378,0.00008275638,0.0024772508],"study_design_scores_gemma":[0.0011947767,0.00031843892,0.015149655,0.000016650201,0.00003757358,0.000002697409,0.000035729056,0.00021326076,0.9793987,0.00015910536,0.0032456687,0.0002277052],"about_ca_topic_score_codex":0.000011967252,"about_ca_topic_score_gemma":0.000001056844,"teacher_disagreement_score":0.015573093,"about_ca_system_score_codex":0.0000043360474,"about_ca_system_score_gemma":0.000015906639,"threshold_uncertainty_score":0.76306456},"labels":[],"label_agreement":null},{"id":"W3123485083","doi":"10.1016/j.omtn.2021.01.015","title":"miR-130a activates the VEGFR2/STAT3/HIF1α axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxia","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Queen's University; Directorate for Biological Sciences; National Instruments Corporation; Science Foundation Ireland; Queen's University Belfast; Sir Jules Thorn Charitable Trust; Juvenile Diabetes Research Foundation International; Leverhulme Trust; Sight Research UK; British Heart Foundation","keywords":"Hypoxia (environmental); VEGF receptors; Chemistry; Cell biology; STAT3; Biology; Cancer research; Signal transduction","score_opus":0.01162506622492613,"score_gpt":0.23237388427797143,"score_spread":0.2207488180530453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123485083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914593,0.004086514,0.0018675653,0.00075752346,0.0007434543,0.0005417106,0.00013518562,0.00001262998,0.00039612476],"genre_scores_gemma":[0.9940813,0.001601935,0.0010638479,0.0021938384,0.00041970066,0.00009213259,0.000039668008,0.000062913394,0.0004446276],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793196,0.00036382137,0.0003776632,0.0005331607,0.00031497324,0.0004784239],"domain_scores_gemma":[0.9986921,0.000039254406,0.00015394056,0.000831197,0.00018794902,0.00009556658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038769704,0.00032541624,0.00035505477,0.000060061127,0.00018670602,0.000058743215,0.0005363353,0.0001867863,0.000060965816],"category_scores_gemma":[0.00007574731,0.00022606595,0.000290203,0.00036551303,0.00022907212,0.000011420182,0.00019435378,0.0002488313,0.000009590633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023462728,0.00011668542,0.000074969925,0.000009835964,0.00019212444,0.000008754189,0.0011950424,0.0002986246,0.9911336,0.00022628163,0.00052740035,0.0059820884],"study_design_scores_gemma":[0.0009935661,0.00016949429,0.0013744464,0.000017254259,0.000027368967,0.000016405656,0.0003980072,0.00002774785,0.84856063,0.0001888224,0.14798948,0.00023680119],"about_ca_topic_score_codex":0.0002447812,"about_ca_topic_score_gemma":0.00020475681,"teacher_disagreement_score":0.14746207,"about_ca_system_score_codex":0.00003397063,"about_ca_system_score_gemma":0.00017988824,"threshold_uncertainty_score":0.9218702},"labels":[],"label_agreement":null},{"id":"W3127596392","doi":"10.1016/j.omtn.2021.01.032","title":"Circular RNA in tumor metastasis","year":2021,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Circular RNA; microRNA; Metastasis; Biology; Competing endogenous RNA; Carcinogenesis; Translation (biology); RNA; Gene; Epithelial–mesenchymal transition; Cancer research; Autophagy; Computational biology; Tumor progression; Gene expression; Cancer; Long non-coding RNA; Genetics; Messenger RNA","score_opus":0.028061979796576254,"score_gpt":0.3131808237007294,"score_spread":0.28511884390415315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127596392","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033879697,0.99386835,0.0005178913,0.00002273274,0.00031546014,0.0010213475,0.00012319835,0.000048061836,0.00069499784],"genre_scores_gemma":[0.0015468632,0.9947962,0.0005536,0.0007085919,0.0002447367,0.00034612507,0.0012949915,0.00037798073,0.00013088126],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952823,0.0008897427,0.0009486687,0.0015553742,0.00053470384,0.0007891899],"domain_scores_gemma":[0.99699694,0.000027182476,0.00037403574,0.002214935,0.00012417683,0.00026274682],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044242895,0.0010397137,0.0020653799,0.00032146488,0.00009045277,0.0001369316,0.0011894708,0.0006425278,0.0003172958],"category_scores_gemma":[0.00021191937,0.0010275119,0.0020426544,0.0007588749,0.0001803715,0.000007811897,0.0004303572,0.0005413626,0.00012131813],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002751496,0.0004735184,0.000030716765,0.002284368,0.001871588,0.0020368777,0.000022903136,0.000017117589,0.013578224,0.0001715003,0.00089699455,0.9785887],"study_design_scores_gemma":[0.0007251055,0.00010192899,0.000009016143,0.0017078514,0.00043226779,0.00024304677,0.0000212868,0.0000018841932,0.005276037,0.00004607892,0.99036306,0.0010724427],"about_ca_topic_score_codex":0.000020692918,"about_ca_topic_score_gemma":0.0000050025606,"teacher_disagreement_score":0.9894661,"about_ca_system_score_codex":0.00014355822,"about_ca_system_score_gemma":0.0006907771,"threshold_uncertainty_score":0.9992175},"labels":[],"label_agreement":null},{"id":"W3134544032","doi":"10.1016/j.omtn.2021.02.032","title":"Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute on Aging; Weston Brain Institute","keywords":"Amyloid precursor protein; Mutation; Biology; CRISPR; HEK 293 cells; Transmembrane protein; Genetics; Gene; Genome editing; Molecular biology; Alzheimer's disease; Disease; Medicine","score_opus":0.01144269151970417,"score_gpt":0.2817337056394549,"score_spread":0.2702910141197507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134544032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9672622,0.0010060954,0.030830078,0.00037519014,0.000058530062,0.00043513463,0.000006216106,0.0000020818325,0.000024458419],"genre_scores_gemma":[0.99616784,0.00003121625,0.0033867396,0.00023395593,0.000027619573,0.00008966336,0.00003599544,0.000014892428,0.000012049074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991831,0.00009903786,0.0002729829,0.00016844487,0.00013772401,0.00013872124],"domain_scores_gemma":[0.9995563,0.000015018638,0.00006154361,0.00029103926,0.000060858274,0.000015250402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003256353,0.00009782373,0.00009859999,0.000026356272,0.000038623064,0.00000935146,0.00021017947,0.00005869665,0.0000033940257],"category_scores_gemma":[0.000049735307,0.000062369145,0.000075170894,0.00018580876,0.000021409554,0.0000020951734,0.000047256937,0.00006222057,2.3639747e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057468827,0.00007899799,0.00006002615,0.000016979659,0.000022085042,0.0000016643804,0.0010139266,0.0050239507,0.9644259,0.000012360088,0.000007674093,0.029278934],"study_design_scores_gemma":[0.00041883165,0.00007274239,0.0058494667,0.000019304836,0.000005439361,0.000004843067,0.00067449774,0.00045244658,0.99136734,0.000058550628,0.0010058398,0.00007067479],"about_ca_topic_score_codex":0.0000065754552,"about_ca_topic_score_gemma":0.000054927164,"teacher_disagreement_score":0.02920826,"about_ca_system_score_codex":0.000014598449,"about_ca_system_score_gemma":0.00008355446,"threshold_uncertainty_score":0.25433397},"labels":[],"label_agreement":null},{"id":"W31760376","doi":"10.1016/j.omtn.2019.10.015","title":"ESD and Ionizing Radiation Effects on Ultrathin Body SOI and Multiple Gate Technologies","year":2010,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Electrostatic Discharge in Electronics","field":"Engineering","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Science Foundation of Zhejiang Province; Canadian Institutes of Health Research; China Scholarship Council","keywords":"Silicon on insulator; NMOS logic; Electrostatic discharge; CMOS; Electrical engineering; Electronic engineering; MOSFET; Clamping; Optoelectronics; Materials science; Engineering; Transistor; Voltage; Silicon","score_opus":0.002415278345457162,"score_gpt":0.18905297391721343,"score_spread":0.18663769557175627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W31760376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926626,0.0032483144,0.0024095767,0.0002647628,0.00015886637,0.00034100752,0.0000027203962,0.00071945746,0.00019268307],"genre_scores_gemma":[0.99712235,0.0011161818,0.0014676411,0.00013983763,0.000027022172,0.000029552994,0.000009163299,0.0000771223,0.00001115869],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990263,0.000029889363,0.00015164487,0.00026366106,0.00015000631,0.0003785196],"domain_scores_gemma":[0.9994936,0.00010484015,0.00003395624,0.00029663107,0.000018331972,0.00005264062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015230733,0.00024275646,0.00018755045,0.00011288699,0.00010429037,0.00009433996,0.00013923147,0.00019162704,0.0000046385285],"category_scores_gemma":[0.0000894045,0.00023286388,0.00003512602,0.00014913792,0.000073240146,0.00011205645,0.000019748059,0.0005142583,0.000010281867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016543667,0.000017326294,0.00045000078,0.000028152921,0.000055627035,0.000013263623,0.00028060388,0.00022273141,0.91217965,0.0018547254,0.000032656597,0.08484873],"study_design_scores_gemma":[0.0009780674,0.00027435244,0.0012764913,0.000023192004,0.0000119967535,0.000021629847,0.000031532174,0.02226853,0.9697721,0.0027118514,0.0023354008,0.00029488272],"about_ca_topic_score_codex":0.000005231367,"about_ca_topic_score_gemma":0.0000047858707,"teacher_disagreement_score":0.084553845,"about_ca_system_score_codex":0.000032471104,"about_ca_system_score_gemma":0.0000118673515,"threshold_uncertainty_score":0.94959134},"labels":[],"label_agreement":null},{"id":"W3190330215","doi":"10.1016/j.omtn.2021.07.015","title":"The role of SAXS and molecular simulations in 3D structure elucidation of a DNA aptamer against lung cancer","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Russian Foundation for Basic Research; Japan Society for the Promotion of Science; Horizon 2020 Framework Programme; Tomsk State University; Russian Science Foundation; Bundesministerium für Bildung und Forschung; Office of Science; Deutsches Elektronen-Synchrotron; Argonne National Laboratory; U.S. Department of Energy; European Commission; China Scholarship Council","keywords":"Aptamer; Small-angle X-ray scattering; Oligonucleotide; DNA; Chemistry; Molecule; RNA; Molecular dynamics; Fragment molecular orbital; Biophysics; Scattering; Biology; Molecular orbital; Biochemistry; Gene; Computational chemistry; Molecular biology; Physics","score_opus":0.003521958992351974,"score_gpt":0.25548907955014116,"score_spread":0.2519671205577892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3190330215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98816466,0.009302409,0.0020209404,0.00017051739,0.000020990125,0.00016119788,0.000044904413,0.000009799595,0.000104570165],"genre_scores_gemma":[0.9948174,0.0022301706,0.0025167356,0.00026128092,0.000020208756,0.00000621712,0.000102134676,0.000026161388,0.000019712033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892193,0.000121729936,0.00029980406,0.0003101585,0.00016944848,0.0001769169],"domain_scores_gemma":[0.9991646,0.000014682934,0.00016264163,0.0004288603,0.00019384094,0.000035380457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095402014,0.00016764799,0.00021323033,0.000057032164,0.000065467604,0.000017773027,0.0001327149,0.00016139253,0.0000045500033],"category_scores_gemma":[0.000049361406,0.00013402202,0.00010317017,0.0002702032,0.00015658744,0.0000060072794,0.0000743597,0.00009977388,5.64426e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005583902,0.000036009355,0.0030708546,0.000008730768,0.0001385277,0.000004296823,0.00005327355,0.00046000862,0.96625036,0.00010730857,0.0000068577515,0.029807923],"study_design_scores_gemma":[0.00037550708,0.000057430596,0.0011379092,0.000029631043,0.000030919302,0.0000028871366,0.000083084764,0.001875421,0.9924959,0.000391589,0.003370724,0.00014901243],"about_ca_topic_score_codex":0.000022676231,"about_ca_topic_score_gemma":0.00006794988,"teacher_disagreement_score":0.029658912,"about_ca_system_score_codex":0.000016550353,"about_ca_system_score_gemma":0.00006574009,"threshold_uncertainty_score":0.5465259},"labels":[],"label_agreement":null},{"id":"W3206162646","doi":"10.1016/j.omtn.2021.10.016","title":"Dual inhibition of TMPRSS2 and Cathepsin B prevents SARS-CoV-2 infection in iPS cells","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute for Frontier Life and Medical Sciences, Kyoto University; Kyoto University; Canadian Internet Registration Authority; Japan Agency for Medical Research and Development; Gladstone Institutes","keywords":"Proteases; Cathepsin B; TMPRSS2; Biology; Virology; Basigin; Coronavirus; Cathepsin L; Receptor; Cathepsin; Infectivity; Molecular biology; Virus; Enzyme; Coronavirus disease 2019 (COVID-19); Medicine; Biochemistry; Disease; Internal medicine; Matrix metalloproteinase","score_opus":0.027486656015496932,"score_gpt":0.3172958274876715,"score_spread":0.28980917147217455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206162646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971188,0.0010202714,0.00040102363,0.00018528549,0.000083706924,0.0004060085,0.000005393252,0.000036175967,0.0007433356],"genre_scores_gemma":[0.9911933,0.00014393925,0.00025610463,0.00826326,0.000043104137,0.000027144855,0.000010182861,0.00004348221,0.000019504172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842584,0.0001856656,0.00032261736,0.00037471796,0.00040511647,0.000286033],"domain_scores_gemma":[0.999381,0.000029180961,0.000073843825,0.0003602637,0.00012672815,0.00002897069],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003126552,0.00018661824,0.0003310772,0.00022848306,0.00004187076,0.000027531978,0.000050339782,0.00018337251,0.00001609694],"category_scores_gemma":[0.000050317838,0.00018225679,0.00012185587,0.0005148185,0.000110720015,0.00009380513,0.000068974674,0.0002790879,0.000020667223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025980046,0.00043557942,0.025657972,0.00009053051,0.00006797915,0.00035217917,0.0005515635,6.352121e-7,0.96400607,0.00007471001,0.000050193878,0.00845278],"study_design_scores_gemma":[0.003030159,0.0003891827,0.017177392,0.00013666644,0.000021430202,0.00007282481,0.000045078985,0.000072641335,0.97100323,0.0005003096,0.0074005965,0.00015045884],"about_ca_topic_score_codex":0.00028894655,"about_ca_topic_score_gemma":0.00004562256,"teacher_disagreement_score":0.008480581,"about_ca_system_score_codex":0.00009355756,"about_ca_system_score_gemma":0.00016452906,"threshold_uncertainty_score":0.74322164},"labels":[],"label_agreement":null},{"id":"W3208740981","doi":"10.1016/j.omtn.2021.10.015","title":"lncRNA DDGC participates in premature ovarian insufficiency through regulating RAD51 and WT1","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Key Research and Development Program of China; Shandong University","keywords":"Premature ovarian insufficiency; Premature ovarian failure; RAD51; Medicine; Cancer research; Internal medicine; Biology; Genetics; DNA repair; DNA","score_opus":0.01484607280167564,"score_gpt":0.27955081068676985,"score_spread":0.2647047378850942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3208740981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96741027,0.0125930505,0.016803402,0.00084002723,0.00014554743,0.00044069873,0.000011525388,0.000040226343,0.0017152701],"genre_scores_gemma":[0.9913746,0.0015227527,0.0053042234,0.001130737,0.00009690083,0.00006582499,0.000089379355,0.000098392964,0.00031718184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973603,0.0003195459,0.00038866358,0.0008737747,0.00038994197,0.0006677595],"domain_scores_gemma":[0.9987769,0.0000174015,0.0000974499,0.00081505376,0.00014900365,0.00014416585],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034322764,0.00033922895,0.00032171118,0.00008442003,0.00014585724,0.000114286086,0.00030758785,0.00042365622,0.000100410754],"category_scores_gemma":[0.00018187496,0.0003489291,0.00014600917,0.0005186136,0.00014908031,0.000016143109,0.00030289247,0.0003939227,0.0000096017675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016261998,0.00020379572,0.00019067021,0.000027878246,0.00010293303,0.00017808723,0.00043475817,0.00046644197,0.9904723,0.0011017463,0.0001113269,0.0065474445],"study_design_scores_gemma":[0.0020988912,0.00044096602,0.0012688073,0.0000731221,0.000016500842,0.000121747325,0.0002187219,0.00067172165,0.9764607,0.0014082021,0.016783202,0.00043741113],"about_ca_topic_score_codex":0.000050627517,"about_ca_topic_score_gemma":0.000025814983,"teacher_disagreement_score":0.023964355,"about_ca_system_score_codex":0.000049829712,"about_ca_system_score_gemma":0.00023917983,"threshold_uncertainty_score":0.9998963},"labels":[],"label_agreement":null},{"id":"W3209325284","doi":"10.1016/j.omtn.2021.10.013","title":"Diverging targets mediate the pathological role of miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Guangzhou Science and Technology Program key projects; National Natural Science Foundation of China","keywords":"Fibrosis; Cardiac fibrosis; Downregulation and upregulation; Medicine; microRNA; Muscle hypertrophy; Coactivator; Internal medicine; PPARGC1A; Cancer research; Transcription factor; Endocrinology; Biology; Gene","score_opus":0.006416551167951252,"score_gpt":0.2167247468750815,"score_spread":0.21030819570713025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209325284","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93185735,0.065796696,0.00018984906,0.0013108233,0.00011682037,0.00038157613,0.000045594956,0.000049628718,0.00025165355],"genre_scores_gemma":[0.992313,0.0047327937,0.0019669735,0.00071217516,0.000101151854,0.000021131498,0.000052943895,0.000062086445,0.000037737598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979116,0.00029818868,0.00039877358,0.00055646675,0.00043480963,0.00040018762],"domain_scores_gemma":[0.9990114,0.000097051496,0.00012976026,0.0004460282,0.00012619937,0.0001895758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004952338,0.00030670108,0.0006918318,0.000054359185,0.00022915451,0.00006597658,0.00011052295,0.00021156897,0.000030926236],"category_scores_gemma":[0.000099257646,0.00020622848,0.0003442514,0.00021212592,0.0002448645,0.00006879943,0.00020843191,0.00032622422,0.000002637243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000109842396,0.000081566664,0.009788773,0.000059287057,0.00021928221,0.000042388667,0.0014715982,0.000009062369,0.96447474,0.000050847877,0.00009721516,0.023595413],"study_design_scores_gemma":[0.0035613654,0.0008166219,0.05815677,0.00036129626,0.00046979598,0.00023668825,0.0018119172,0.0035440968,0.9080091,0.0006004874,0.021703983,0.000727854],"about_ca_topic_score_codex":0.000032511354,"about_ca_topic_score_gemma":3.691221e-7,"teacher_disagreement_score":0.061063904,"about_ca_system_score_codex":0.000027757073,"about_ca_system_score_gemma":0.000041619587,"threshold_uncertainty_score":0.84097534},"labels":[],"label_agreement":null},{"id":"W3210086271","doi":"10.1016/j.omtn.2021.10.020","title":"11C-radiolabeled aptamer for imaging of tumors and metastases using positron emission tomography- computed tomography","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Positron emission tomography; Preclinical imaging; Molecular imaging; Nuclear medicine; In vivo; Medicine; Metastasis; Cancer; Positron Emission Tomography-Computed Tomography; Radiology; Biology; Molecular biology; Internal medicine","score_opus":0.008702091717425732,"score_gpt":0.2632522011119731,"score_spread":0.25455010939454736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210086271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9354168,0.008007773,0.056112863,0.00008955125,0.000035519188,0.0002243963,0.00004660931,0.000042162676,0.000024301786],"genre_scores_gemma":[0.9322049,0.00028502865,0.06679401,0.00041209027,0.000043155247,0.0000067610104,0.00019358199,0.00004562659,0.0000148773515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856347,0.00013105014,0.00032032226,0.0005348447,0.00016218956,0.00028810272],"domain_scores_gemma":[0.9990307,0.000016035605,0.00017502175,0.00042557702,0.00025837807,0.00009427982],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018396083,0.0002740128,0.00037076403,0.00014950572,0.00012898109,0.00003788838,0.00014130384,0.0001130969,0.000002173906],"category_scores_gemma":[0.000029976738,0.00024955886,0.00036202988,0.00037723398,0.0001820932,0.000008904754,0.00008779716,0.00008224577,6.317009e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015362306,0.00010058193,0.003727119,0.00002482163,0.00029335247,0.000015834075,0.00001903097,0.00001241953,0.98504674,0.000034327753,0.00005362488,0.010518503],"study_design_scores_gemma":[0.0008481443,0.00023351601,0.00059964735,0.000064002816,0.00011022947,0.000062981155,0.00006984701,0.0010149698,0.99472594,0.0002098487,0.001759554,0.00030130486],"about_ca_topic_score_codex":0.0000131175,"about_ca_topic_score_gemma":0.0000015496073,"teacher_disagreement_score":0.010681141,"about_ca_system_score_codex":0.0000096016465,"about_ca_system_score_gemma":0.000043276967,"threshold_uncertainty_score":0.99999565},"labels":[],"label_agreement":null},{"id":"W3214943347","doi":"10.1016/j.omtn.2021.11.025","title":"Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Russian Science Foundation; Siberian Branch, Russian Academy of Sciences; Russian Foundation for Basic Research","keywords":"Phosphodiester bond; Oligonucleotide; Nuclease; Phosphoramidite; Guanidine; Biochemistry; Biology; Phosphomonoesterase; Nucleic acid; Molecular biology; DNA; Chemistry; RNA; Enzyme; Gene; Phosphatase","score_opus":0.005741237946259194,"score_gpt":0.20784695118111704,"score_spread":0.20210571323485785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214943347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99178594,0.005329572,0.000439964,0.00026471177,0.00026430356,0.00025176286,0.00011834233,0.00006258433,0.0014828026],"genre_scores_gemma":[0.99080914,0.0014220704,0.0040202187,0.0016900217,0.00011316412,0.000019045096,0.00038724026,0.00014522245,0.0013938701],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99728733,0.00016577641,0.00062723964,0.00088872697,0.00040862433,0.00062228926],"domain_scores_gemma":[0.9978905,0.000053754557,0.0003365298,0.0011340487,0.0003404242,0.00024479424],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029393565,0.00048933044,0.000559704,0.000057982706,0.00014130863,0.000046628786,0.00049959676,0.0002408824,0.00020378114],"category_scores_gemma":[0.0002503834,0.00052876945,0.000394722,0.00035611523,0.00029839072,0.000015529564,0.00021985122,0.00027028183,0.000034638375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077016786,0.00021314673,0.0012470401,0.00006640955,0.00026492152,0.00048752537,0.00019659122,0.000026220514,0.9916174,0.000038997172,0.004707016,0.00036459396],"study_design_scores_gemma":[0.0026712178,0.00012260354,0.00032125178,0.00008065716,0.000041189687,0.000040430434,0.00047586294,0.000051838015,0.9186106,0.00004339086,0.077006206,0.00053475983],"about_ca_topic_score_codex":0.000027134665,"about_ca_topic_score_gemma":0.000019263127,"teacher_disagreement_score":0.07300678,"about_ca_system_score_codex":0.000043636883,"about_ca_system_score_gemma":0.00017386152,"threshold_uncertainty_score":0.9997164},"labels":[],"label_agreement":null},{"id":"W3216612608","doi":"10.1016/j.omtn.2021.11.027","title":"RETRACTED: Promotion of tumor progression by exosome transmission of circular RNA circSKA3","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Sunnybrook Research Institute","keywords":"Exosome; Microvesicles; In vivo; Breast cancer; Metastasis; Cancer research; Biology; In vitro; Circular RNA; Cancer; RNA; Population; Tumor progression; microRNA; Medicine; Gene","score_opus":0.008825584571294967,"score_gpt":0.25638448779384876,"score_spread":0.2475589032225538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216612608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9725187,0.01701354,0.0093020145,0.00014579704,0.00010651943,0.00041374404,0.000054316584,0.000029698904,0.00041566658],"genre_scores_gemma":[0.99681205,0.0008778873,0.0014415078,0.0001729398,0.00005572021,0.000031119398,0.00045037022,0.00008700986,0.000071386814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977143,0.0002643177,0.0005264881,0.0006085587,0.00056668505,0.00031969033],"domain_scores_gemma":[0.998353,0.000008714734,0.0002923007,0.0008701237,0.00031872522,0.00015714602],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023682592,0.00029619707,0.0003776517,0.00007355192,0.00006472704,0.000020714055,0.00036150572,0.00027544264,0.00016571699],"category_scores_gemma":[0.00009470784,0.00029521916,0.00038781244,0.00032185725,0.00018393216,0.00001260979,0.000083411345,0.00018213784,0.0000041077637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016361052,0.0008425369,0.0012149855,0.00014076591,0.00018008373,0.00006737223,0.000050559007,0.0000168083,0.95695096,0.00003279202,0.0002786708,0.040060844],"study_design_scores_gemma":[0.0013067441,0.00047954288,0.002795297,0.00014624311,0.00004935151,0.00005154566,0.000029361236,0.00004358712,0.9844921,0.00021793516,0.010085676,0.000302598],"about_ca_topic_score_codex":0.0000043805608,"about_ca_topic_score_gemma":2.8304552e-7,"teacher_disagreement_score":0.039758246,"about_ca_system_score_codex":0.000024454977,"about_ca_system_score_gemma":0.000183988,"threshold_uncertainty_score":0.99995},"labels":[],"label_agreement":null},{"id":"W3217124805","doi":"10.1016/j.omtn.2021.11.014","title":"Deciphering a TB-related DNA methylation biomarker and constructing a TB diagnostic classifier","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Public Health Ontario; University of Toronto; University Health Network","funders":"National Science and Technology Program during the Twelfth Five-year Plan Period; West China Hospital, Sichuan University; Sichuan University","keywords":"DNA methylation; Logistic regression; Biomarker; Methylation; Biomarker discovery; Classifier (UML); Artificial intelligence; Oncology; Internal medicine; Medicine; Biology; Computational biology; Bioinformatics; Computer science; DNA; Gene; Genetics; Gene expression","score_opus":0.028378460154883357,"score_gpt":0.31125247566897224,"score_spread":0.28287401551408886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3217124805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9827418,0.0072368206,0.0024599263,0.004409461,0.00012315018,0.00030427577,0.000003438202,0.00008406396,0.0026370871],"genre_scores_gemma":[0.99192953,0.0015732673,0.0038969398,0.0023004801,0.00004296619,0.000029863713,0.000041022617,0.00005226853,0.00013364128],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99801236,0.00041021453,0.0003847144,0.00047057116,0.000253326,0.00046878844],"domain_scores_gemma":[0.9985941,0.0005464443,0.00007928963,0.000373583,0.00013977147,0.0002668259],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005077296,0.00021599069,0.00043515206,0.000117066134,0.000115087474,0.000041663636,0.000075133044,0.00023852388,0.0005407203],"category_scores_gemma":[0.0020436672,0.00018917504,0.00015006255,0.00039196087,0.0001955173,0.00007873746,0.000080486854,0.00033735126,0.00004069428],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001250297,0.00009386646,0.06637016,0.000032403466,0.0004565403,0.00086933735,0.0002446437,0.0000064205956,0.7789008,0.00060616265,0.0001750986,0.15211956],"study_design_scores_gemma":[0.014719615,0.0010470111,0.61687076,0.0006194482,0.00037398993,0.004219381,0.0015240413,0.009637041,0.28915933,0.005630762,0.054994784,0.001203841],"about_ca_topic_score_codex":0.00003412478,"about_ca_topic_score_gemma":0.0000050724857,"teacher_disagreement_score":0.5505006,"about_ca_system_score_codex":0.000068518726,"about_ca_system_score_gemma":0.0001045529,"threshold_uncertainty_score":0.7714335},"labels":[],"label_agreement":null},{"id":"W4220704556","doi":"10.1016/j.omtn.2022.03.022","title":"CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer’s disease PSEN1 M146L mutation","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Toronto; University Health Network","funders":"National Institute of General Medical Sciences; National Institutes of Health; Åhlén-stiftelsen; Vetenskapsrådet; Alzheimerfonden; Massachusetts General Hospital; Gun och Bertil Stohnes Stiftelse; Hjärnfonden; National Institute on Aging; Deutsche Forschungsgemeinschaft; Stiftelsen för Gamla Tjänarinnor","keywords":"CRISPR; PSEN1; Disease; Mutation; Amyloid (mycology); Medicine; Dementia; Cancer research; Alzheimer's disease; Biology; Amyloid precursor protein; Genetics; Pathology; Gene","score_opus":0.01164431016907894,"score_gpt":0.2858149682671727,"score_spread":0.2741706580980937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220704556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902547,0.0047068326,0.0034865378,0.00073302636,0.00007104677,0.0005352635,0.00002311214,0.000032456774,0.00015700441],"genre_scores_gemma":[0.99834925,0.00012774054,0.00022108141,0.0005112318,0.00008344998,0.00030968417,0.00017576123,0.00007272198,0.00014909923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850994,0.0001761289,0.00021242772,0.0004707255,0.00028194845,0.00034884212],"domain_scores_gemma":[0.9991637,0.000010260099,0.0000693041,0.0006108026,0.00003238589,0.0001135413],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014336144,0.00028354497,0.00017116562,0.00007015369,0.00027618377,0.000044795346,0.00029065815,0.00005791457,0.00007426569],"category_scores_gemma":[0.0000067289347,0.00021947363,0.00012953766,0.00017937568,0.00008532174,0.000005317562,0.00009864496,0.00013430775,0.0000040176965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010161897,0.0003068652,0.0023495434,0.000007988003,0.00029365477,0.0002550343,0.0007640088,0.0747701,0.9129558,0.00012489584,0.00068160245,0.006474294],"study_design_scores_gemma":[0.0056582955,0.0047336384,0.047131576,0.00002607006,0.0001719092,0.00007739767,0.0007751604,0.0013653764,0.84134585,0.00025067895,0.09737329,0.0010907378],"about_ca_topic_score_codex":0.000079165875,"about_ca_topic_score_gemma":0.00010318254,"teacher_disagreement_score":0.09669169,"about_ca_system_score_codex":0.00005551411,"about_ca_system_score_gemma":0.000081185004,"threshold_uncertainty_score":0.89498746},"labels":[],"label_agreement":null},{"id":"W4221097003","doi":"10.1016/j.omtn.2022.03.007","title":"The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Guangdong Provincial People's Hospital","keywords":"Doxorubicin; Gene silencing; Cancer research; Downregulation and upregulation; Cardiotoxicity; Cardiac fibrosis; Fibrosis; Biology; Cell biology; Pharmacology; Chemistry; Medicine; Internal medicine; Chemotherapy; Biochemistry","score_opus":0.007972257971569564,"score_gpt":0.2262797334389888,"score_spread":0.21830747546741924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221097003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96105784,0.035804834,0.0010634221,0.00059104414,0.00035494426,0.00043292952,0.00003961908,0.000054748285,0.0006006114],"genre_scores_gemma":[0.99518394,0.0023903311,0.00026242415,0.0014763965,0.0001934981,0.00015589816,0.000107879176,0.000115212475,0.000114397],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99754465,0.00036844544,0.0003204728,0.000702904,0.00052764104,0.00053589646],"domain_scores_gemma":[0.9985077,0.000039222185,0.0001270501,0.0010713319,0.000078221055,0.00017651558],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054730906,0.00033203734,0.0002464255,0.00006619022,0.001023753,0.00013237861,0.00064403564,0.00012067649,0.000054605007],"category_scores_gemma":[0.00010681927,0.00030035427,0.0003223762,0.00022374078,0.00021810303,0.000008339591,0.0005513295,0.00028417978,0.000010060932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012331663,0.00005873071,0.0012431109,0.0000082209845,0.00021235993,0.000024475596,0.0000998092,0.0005850569,0.97277784,0.00021843032,0.0006168122,0.024031831],"study_design_scores_gemma":[0.0020957666,0.00055378594,0.003959262,0.000015034212,0.0001039883,0.00015470611,0.00083435944,0.00063232204,0.62911856,0.0020469811,0.3594742,0.0010110362],"about_ca_topic_score_codex":0.000023256556,"about_ca_topic_score_gemma":0.0000012348113,"teacher_disagreement_score":0.3588574,"about_ca_system_score_codex":0.000057694408,"about_ca_system_score_gemma":0.000103943035,"threshold_uncertainty_score":0.99994487},"labels":[],"label_agreement":null},{"id":"W4281647929","doi":"10.1016/j.omtn.2022.05.026","title":"Mincle-binding DNA aptamer demonstrates therapeutic potential in a model of inflammatory bowel disease","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Cumming School of Medicine, University of Calgary","keywords":"Aptamer; Inflammatory bowel disease; DNA; Computational biology; Inflammatory Bowel Diseases; Disease; Medicine; Biology; Genetics; Internal medicine","score_opus":0.008658538890601135,"score_gpt":0.23937173562741973,"score_spread":0.2307131967368186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281647929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916362,0.0013646691,0.00638874,0.00015766206,0.000037360755,0.00025058663,0.00004202321,0.000038711823,0.00008403252],"genre_scores_gemma":[0.99723244,0.0003303715,0.0016133994,0.0005012717,0.000027096345,0.000045352,0.00009257782,0.00005372826,0.000103764956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836576,0.00017745838,0.0003576725,0.00046532432,0.00030927802,0.0003244871],"domain_scores_gemma":[0.99918884,0.000005355238,0.00015886567,0.0005030317,0.000053005588,0.00009090941],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025204214,0.0002535763,0.00022861134,0.00016582097,0.00014001084,0.000017901044,0.00034230735,0.00010312408,0.000013395347],"category_scores_gemma":[0.000011212801,0.00025106076,0.00026458432,0.00020464562,0.0001709643,0.000007712092,0.00019243178,0.00019020845,0.0000010370054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043961836,0.00018735132,0.0033077355,0.000010192351,0.00011206964,0.000036235826,0.000045122022,0.0045613674,0.9873474,0.00010781698,0.000024736108,0.0038203304],"study_design_scores_gemma":[0.0010171025,0.00030490433,0.0012266902,0.000015886028,0.000050687744,0.000010190997,0.00017976704,0.014365141,0.98049146,0.0011159792,0.00077295385,0.0004492506],"about_ca_topic_score_codex":0.0000073571077,"about_ca_topic_score_gemma":0.0000030595995,"teacher_disagreement_score":0.009803774,"about_ca_system_score_codex":0.000042812106,"about_ca_system_score_gemma":0.00010958595,"threshold_uncertainty_score":0.99999416},"labels":[],"label_agreement":null},{"id":"W4283375432","doi":"10.1016/j.omtn.2022.06.015","title":"Developing antisense oligonucleotides for a TECPR2 mutation-induced, ultra-rare neurological disorder using patient-derived cellular models","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nuclear Laboratories","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Exon; Exon skipping; Induced pluripotent stem cell; Biology; Mutation; Frameshift mutation; Hypotonia; Molecular biology; Cell biology; Bioinformatics; Genetics; Cancer research; Medicine; Gene; Alternative splicing; Embryonic stem cell","score_opus":0.024245620748102624,"score_gpt":0.24214458708378617,"score_spread":0.21789896633568354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283375432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9618808,0.0010033275,0.03555541,0.0002642872,0.00022302245,0.0009057629,0.000058389196,0.000043678945,0.00006533219],"genre_scores_gemma":[0.98792744,0.00017176205,0.008533493,0.0027774714,0.000019599365,0.00019025398,0.00023743983,0.00012701075,0.000015557975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778765,0.00018919026,0.00038554322,0.0007860368,0.00031726694,0.0005343171],"domain_scores_gemma":[0.9992082,0.000015340904,0.00015412564,0.000415276,0.00010107175,0.000105949715],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012675476,0.00037975865,0.00026067466,0.00009977633,0.0006106836,0.00006129625,0.0003796566,0.00013406728,0.00004000756],"category_scores_gemma":[0.000029213943,0.0004046384,0.0002340848,0.00023288568,0.00007699902,0.00001098074,0.00022494356,0.00017523723,0.0000025292907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002603028,0.00013983225,0.00020250681,0.000012453952,0.00009301077,0.000050152215,0.0002656149,0.012020906,0.98031104,0.00013665194,0.000030367291,0.0064771553],"study_design_scores_gemma":[0.0023021507,0.0016188707,0.00072961376,0.000007981605,0.00003088632,0.00010222561,0.0006880674,0.0069369953,0.9768545,0.0015163738,0.008341925,0.0008703933],"about_ca_topic_score_codex":0.000019638295,"about_ca_topic_score_gemma":0.0000034273926,"teacher_disagreement_score":0.027021917,"about_ca_system_score_codex":0.000033034157,"about_ca_system_score_gemma":0.00013169576,"threshold_uncertainty_score":0.99984056},"labels":[],"label_agreement":null},{"id":"W4297182209","doi":"10.1016/j.omtn.2022.09.017","title":"Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eisai Canada; Japan Agency for Medical Research and Development","keywords":"Immunogenicity; Immune system; Messenger RNA; Receptor; Titer; Chemistry; Biology; Virology; Immunology; Biochemistry; Gene; Virus","score_opus":0.014896474973559518,"score_gpt":0.23809539500790883,"score_spread":0.22319892003434932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297182209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98890316,0.009191271,0.001294089,0.00017411009,0.00003168203,0.00038422603,0.000010784101,0.000005559806,0.000005121632],"genre_scores_gemma":[0.9975389,0.0013022353,0.00081984285,0.00018640113,0.000015024953,0.00005980441,0.00002349524,0.000022662358,0.000031636286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991583,0.00016919173,0.00019652297,0.00026332532,0.00006925648,0.0001433802],"domain_scores_gemma":[0.9996833,0.000025778409,0.0000717655,0.00013012858,0.000056506797,0.00003248838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038890212,0.000121732395,0.00015212908,0.00006797978,0.000091418195,0.00001716899,0.00009605142,0.000056042325,0.000010307818],"category_scores_gemma":[0.000046069657,0.00012345923,0.000027337568,0.00007399815,0.00003256064,0.000006177453,0.00011120849,0.0000464781,1.6842979e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033131689,0.00005747844,0.00039148232,0.00002069773,0.000036471796,0.0000025351749,0.00020874203,0.0006922024,0.99406236,0.000033865326,0.00002331518,0.0011576887],"study_design_scores_gemma":[0.00166227,0.001934187,0.004644751,0.0000118728185,0.000010976344,0.000014107568,0.000114808834,0.0017057093,0.98900616,0.00008914019,0.0006602177,0.0001458055],"about_ca_topic_score_codex":0.0000053130975,"about_ca_topic_score_gemma":0.0000010884646,"teacher_disagreement_score":0.008635741,"about_ca_system_score_codex":0.0000084330395,"about_ca_system_score_gemma":0.000022477096,"threshold_uncertainty_score":0.5034522},"labels":[],"label_agreement":null},{"id":"W4299287602","doi":"10.1016/j.omtn.2022.09.022","title":"Prime editing optimized RTT permits the correction of the c.8713C>T mutation in DMD gene","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Dystrophin; Duchenne muscular dystrophy; Biology; Genetics; Gene; Molecular biology; Point mutation; Genome editing; CRISPR; Mutation","score_opus":0.005030096959285638,"score_gpt":0.2462696659657221,"score_spread":0.24123956900643648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4299287602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98478955,0.0016980788,0.011781942,0.00026508968,0.00072124205,0.00036624217,0.0000071286195,0.000013365607,0.00035735144],"genre_scores_gemma":[0.9986284,0.000094809155,0.00045776454,0.00033054888,0.00010274061,0.00007593638,0.00003527949,0.000036261346,0.00023828642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889135,0.00019034323,0.000234723,0.00024744403,0.000238858,0.0001972488],"domain_scores_gemma":[0.9993953,0.000013053117,0.00010394095,0.00042020544,0.000043028063,0.000024438119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003281603,0.00014376479,0.00012859522,0.000043334916,0.0001714478,0.000014570231,0.00033175436,0.00006670733,0.00005085268],"category_scores_gemma":[0.000045915935,0.00010957416,0.00014185162,0.00024162576,0.000055605007,0.0000030660801,0.00016059606,0.00018630565,0.0000011085679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007543296,0.00004396626,0.00032310898,0.0000031077548,0.00003767652,0.0000038073006,0.00033668682,0.06720002,0.92102754,0.000010323112,0.00011803,0.010820307],"study_design_scores_gemma":[0.0011003587,0.00020408962,0.0038424549,0.000007247411,0.000013589729,0.000041907064,0.00033984773,0.006758978,0.9792997,0.000025691035,0.008214335,0.0001517541],"about_ca_topic_score_codex":0.000027219123,"about_ca_topic_score_gemma":0.000005872995,"teacher_disagreement_score":0.060441043,"about_ca_system_score_codex":0.000034374352,"about_ca_system_score_gemma":0.000045524328,"threshold_uncertainty_score":0.44683045},"labels":[],"label_agreement":null},{"id":"W4300427557","doi":"10.1016/j.omtn.2022.09.014","title":"Treating the diabetic wound through miR inhibitor cocktails: A question of timing?","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Diabetes mellitus; Medicine; microRNA; Wound healing; Amputation; Type 2 diabetes; Angiogenesis; Tissue repair; Vascular permeability; Endothelial dysfunction; Internal medicine; Endocrinology; Cancer research; Bioinformatics; Surgery; Chemistry; Biology","score_opus":0.02213060544589555,"score_gpt":0.29737093779807394,"score_spread":0.2752403323521784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4300427557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929975,0.002568838,0.00028926643,0.0017107826,0.0001551179,0.00056608533,0.000010668519,0.00007587681,0.0016258137],"genre_scores_gemma":[0.99679404,0.00007638189,0.0010515081,0.0013700929,0.0000714796,0.00013230053,0.000041795316,0.000051108076,0.00041128628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985182,0.0002300512,0.00028944013,0.00025904813,0.0004460628,0.00025714107],"domain_scores_gemma":[0.9992315,0.00006537811,0.00013517204,0.000451999,0.000060674578,0.000055271186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029349502,0.00018247568,0.00029444575,0.000057197856,0.0003616624,0.000019662302,0.00013043421,0.000059148242,0.00023629019],"category_scores_gemma":[0.000032302905,0.00013104915,0.00016552293,0.00028023304,0.00010385167,0.000039176815,0.000054878816,0.00026151308,0.000015366562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034683847,0.0059982417,0.10149213,0.0004077861,0.003207879,0.0009542603,0.035068054,0.0008929982,0.73545235,0.007615528,0.0022168595,0.10322554],"study_design_scores_gemma":[0.046487637,0.022948973,0.082826726,0.0012393461,0.0022083835,0.0011521764,0.011563883,0.0039735516,0.6256318,0.01974378,0.179958,0.0022657088],"about_ca_topic_score_codex":0.00020567758,"about_ca_topic_score_gemma":0.0000018121111,"teacher_disagreement_score":0.17774114,"about_ca_system_score_codex":0.00016045688,"about_ca_system_score_gemma":0.000083625484,"threshold_uncertainty_score":0.53440297},"labels":[],"label_agreement":null},{"id":"W4307721860","doi":"10.1016/j.omtn.2022.10.012","title":"Mitochondrion-targeted RNA therapies as a potential treatment strategy for mitochondrial diseases","year":2022,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Canada Research Chairs","keywords":"Heteroplasmy; Mitochondrion; RNA interference; RNA; Mitochondrial disease; Mitochondrial DNA; Biology; Disease; Nanocarriers; Pharmacology; Medicine; Bioinformatics; Drug; Genetics; Gene; Pathology","score_opus":0.031677258726825086,"score_gpt":0.30609609284213046,"score_spread":0.2744188341153054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307721860","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00040632085,0.9863841,0.004358584,0.00007075955,0.0036217473,0.0037591455,0.00095769874,0.00011059469,0.0003310372],"genre_scores_gemma":[0.00007617584,0.9812418,0.0010068965,0.0005081211,0.0021278905,0.0030118052,0.0073528546,0.0003600041,0.0043144403],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954128,0.0008127682,0.00086506386,0.0016136164,0.00041413165,0.00088160107],"domain_scores_gemma":[0.9976337,0.000069541675,0.0005100818,0.0013748134,0.00010439872,0.00030749117],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011875029,0.0012201146,0.0017179962,0.00026284056,0.0005086567,0.00015246449,0.0008066978,0.0008893762,0.0019757815],"category_scores_gemma":[0.000086672095,0.00093086564,0.0025351788,0.00029047523,0.00018198787,0.000010211892,0.00018265056,0.00034106095,0.00009508621],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013721591,0.0006081135,8.961252e-7,0.00039141363,0.0022954813,0.000150028,0.00007434132,0.00005925835,0.055662464,0.00020004182,0.004231682,0.9349541],"study_design_scores_gemma":[0.0029439572,0.004467906,6.418255e-7,0.00010611698,0.00077344064,0.00016086613,0.000062919244,0.000005520243,0.002308091,0.00021331735,0.98793876,0.0010184611],"about_ca_topic_score_codex":0.00003176916,"about_ca_topic_score_gemma":0.000006162133,"teacher_disagreement_score":0.9837071,"about_ca_system_score_codex":0.00015577457,"about_ca_system_score_gemma":0.00081906916,"threshold_uncertainty_score":0.9993142},"labels":[],"label_agreement":null},{"id":"W4310676081","doi":"10.1016/j.omtn.2022.11.024","title":"Formulation, inflammation, and RNA sensing impact the immunogenicity of self-amplifying RNA vaccines","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"Biotechnology and Biological Sciences Research Council; Coalition for Epidemic Preparedness Innovations","keywords":"Immunogenicity; RNA; Inflammation; Virology; Immunology; Medicine; Biology; Immune system; Genetics; Gene","score_opus":0.009316087565917562,"score_gpt":0.24672431625109964,"score_spread":0.23740822868518208,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310676081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942251,0.0025141742,0.0025725043,0.00020611397,0.00007512735,0.00023779065,0.000011627456,0.000017769038,0.00013979309],"genre_scores_gemma":[0.99872833,0.0004122502,0.00040187693,0.00026824806,0.00006977583,0.000010157707,0.000051004146,0.000028537404,0.00002980509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895,0.00014237223,0.0002778648,0.0002450755,0.00018697715,0.00019767997],"domain_scores_gemma":[0.99922806,0.000013988285,0.00016504255,0.00042627743,0.0001294536,0.00003717767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002922737,0.00017413068,0.00015717083,0.000055149827,0.0003107856,0.0000359179,0.00024049549,0.00006569171,0.000049799666],"category_scores_gemma":[0.000020730104,0.00013611467,0.00015345821,0.00014863492,0.00003334678,0.00001026407,0.00019549514,0.000119864904,0.0000015999941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016770094,0.000021285668,0.0015197204,0.000005754186,0.00023070598,0.0000025099957,0.00044823464,0.00075340184,0.9851924,0.00005073443,0.000097035874,0.011510482],"study_design_scores_gemma":[0.00088262756,0.0005318459,0.009042531,0.0000069529888,0.000031055744,0.000055953577,0.0002897837,0.0011677776,0.9833198,0.000454825,0.0039848904,0.00023196348],"about_ca_topic_score_codex":0.00006736286,"about_ca_topic_score_gemma":0.000003773665,"teacher_disagreement_score":0.0112785185,"about_ca_system_score_codex":0.000026023727,"about_ca_system_score_gemma":0.000058893762,"threshold_uncertainty_score":0.55505955},"labels":[],"label_agreement":null},{"id":"W4311422707","doi":"10.1016/j.omtn.2022.12.008","title":"Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy","year":2022,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Guangdong Provincial Pearl River Talents Program; Southern Medical University; International Science and Technology Cooperation Program of Shanxi Province; National Natural Science Foundation of China; Sun Yat-sen University; Natural Science Foundation of Guangdong Province","keywords":"Smoothened; Small interfering RNA; Hedgehog signaling pathway; Hedgehog; Signal transduction; Cancer research; Rheumatoid arthritis; Synovitis; RNA interference; Cell biology; Arthritis; Chemistry; Medicine; Biology; Transfection; Immunology; RNA; Gene; Biochemistry","score_opus":0.019361359428208713,"score_gpt":0.23131243067473461,"score_spread":0.2119510712465259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311422707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9418911,0.018491957,0.03766353,0.00020814908,0.00038804807,0.0008667418,0.0000738415,0.00013407491,0.0002825536],"genre_scores_gemma":[0.9911674,0.0016356845,0.004108676,0.001521908,0.00023599723,0.00071434584,0.00028474437,0.00022497549,0.00010623568],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969636,0.00024107017,0.0006489131,0.0009814341,0.00035790738,0.0008070278],"domain_scores_gemma":[0.9987068,0.00005206322,0.00024603488,0.00065018615,0.00018723521,0.00015767045],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00081375847,0.0005438478,0.00051671127,0.000115074035,0.00070729956,0.000093847084,0.0007783791,0.0001945586,0.00009802918],"category_scores_gemma":[0.00012523435,0.0005846813,0.00049727754,0.00022599829,0.00013547852,0.000008721138,0.00043981467,0.0003640679,0.0000053517974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006464153,0.00016239048,0.00012295746,0.000016516116,0.00034893,0.000025475036,0.00057220337,0.0020566387,0.9664933,0.00009646233,0.00025254072,0.029206157],"study_design_scores_gemma":[0.003033696,0.0010095852,0.000017465629,0.00003536247,0.0000051259494,0.000025201358,0.00036814375,0.00040524683,0.93350387,0.00026259036,0.06065041,0.0006833222],"about_ca_topic_score_codex":0.000017233166,"about_ca_topic_score_gemma":0.0000021164012,"teacher_disagreement_score":0.060397867,"about_ca_system_score_codex":0.00007870071,"about_ca_system_score_gemma":0.00012874007,"threshold_uncertainty_score":0.99966043},"labels":[],"label_agreement":null},{"id":"W4315884131","doi":"10.1016/j.omtn.2023.01.005","title":"Identification of potent siRNA targeting complement C5 and its robust activity in pre-clinical models of myasthenia gravis and collagen-induced arthritis","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eisai Canada; Eisai; Japan Agency for Medical Research and Development","keywords":"Eculizumab; Complement system; Complement component 5; Pharmacology; Medicine; In vivo; Immunology; Antibody; Hemolysis; C5a receptor; Biology","score_opus":0.04520328615228401,"score_gpt":0.30148365656508913,"score_spread":0.2562803704128051,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315884131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99462944,0.0035519407,0.00059340906,0.00014194429,0.00013449653,0.00079830625,0.000097217715,0.00003796319,0.000015277878],"genre_scores_gemma":[0.99879545,0.0009619009,0.000051487266,0.000025875965,0.0000071340714,0.00004530474,0.00006160648,0.000023331442,0.00002788712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979662,0.00054450514,0.00076024374,0.0003792016,0.00009626805,0.00025358636],"domain_scores_gemma":[0.9991491,0.0001100107,0.0003391545,0.0002783145,0.00009091521,0.00003253538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008440978,0.00017326076,0.00044885266,0.00016192121,0.00008030813,0.000013176719,0.00017183647,0.00012282029,0.0000583989],"category_scores_gemma":[0.000053848667,0.00017739856,0.000091330716,0.00023073111,0.00011400731,0.0000799451,0.0001529722,0.000098050215,0.000008239282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025427347,0.0002135982,0.0063833497,0.000057011122,0.00017247915,0.0000067404308,0.00067680125,0.00024514503,0.98094255,0.00030661628,0.00007657688,0.010664886],"study_design_scores_gemma":[0.005815828,0.0006521912,0.28897223,0.00021076539,0.00004826633,0.0000111788695,0.00053888594,0.0044427286,0.697699,0.0010415156,0.00020586704,0.0003615091],"about_ca_topic_score_codex":0.00007913188,"about_ca_topic_score_gemma":0.000019612213,"teacher_disagreement_score":0.2832435,"about_ca_system_score_codex":0.000021722251,"about_ca_system_score_gemma":0.00003172658,"threshold_uncertainty_score":0.7234103},"labels":[],"label_agreement":null},{"id":"W4316506432","doi":"10.1016/j.omtn.2023.01.006","title":"Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Science and Technology Agency; National Center of Neurology and Psychiatry; Precursory Research for Embryonic Science and Technology; Otsuka Pharmaceutical; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Human Frontier Science Program; Nihon Medi-Physics; Japan Agency for Medical Research and Development; Japan Society for the Promotion of Science London; Université Laval","keywords":"Amyotrophic lateral sclerosis; Neurodegeneration; Frontotemporal dementia; Nucleic acid; Oligonucleotide; Systemic administration; In vivo; Medicine; Chemistry; Cytoplasm; Pharmacology; Neuroscience; Cell biology; Cancer research; Biology; Disease; Dementia; Pathology; Biochemistry","score_opus":0.037953464944419806,"score_gpt":0.30503487209371277,"score_spread":0.26708140714929296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316506432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99418026,0.0019106807,0.00038010298,0.0020245982,0.00011657828,0.0010218007,0.000018747538,0.00015032411,0.00019691398],"genre_scores_gemma":[0.99691886,0.0019317481,0.00034414727,0.00036478564,0.000055636654,0.000027868024,0.000056524023,0.00012990653,0.00017051864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99694985,0.00028105162,0.00061295996,0.0005839441,0.0008015569,0.00077066396],"domain_scores_gemma":[0.998833,0.00004518918,0.00013286248,0.0005876093,0.00020562123,0.00019570596],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057376694,0.00034436776,0.0006027271,0.0004821568,0.000104163206,0.000037151298,0.0002541424,0.0002449581,0.00011805391],"category_scores_gemma":[0.000039792933,0.0003084616,0.00023741089,0.0014770158,0.00023329057,0.00013561042,0.00007642984,0.0003680165,0.000026703565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009793398,0.00027719606,0.00048506088,0.00008102621,0.00018419184,0.00012280022,0.0010325385,0.0012112539,0.9728675,0.00018155908,0.00011119062,0.022466376],"study_design_scores_gemma":[0.01017177,0.0013405235,0.061710633,0.00047555706,0.000120610435,0.00012643103,0.00097587606,0.013724577,0.90904,0.0006086496,0.0009859367,0.0007194537],"about_ca_topic_score_codex":0.00041904385,"about_ca_topic_score_gemma":0.0000038844214,"teacher_disagreement_score":0.063827485,"about_ca_system_score_codex":0.00023119828,"about_ca_system_score_gemma":0.0001213076,"threshold_uncertainty_score":0.99993676},"labels":[],"label_agreement":null},{"id":"W4319166193","doi":"10.1016/j.omtn.2023.02.002","title":"The SWIB/MDM2 motif of UBE4B activates the p53 pathway","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa; University of Alberta","funders":"Institute of Cancer Research; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Ministry of Education, India; University of Alberta","keywords":"Ubiquitin ligase; Transactivation; Mdm2; Suppressor; P53 protein; Ubiquitin; Mutant; Cancer research; Cell biology; Biology; F-box protein; Cancer; Genetics; Transcription factor; Apoptosis; Gene","score_opus":0.014137031365968368,"score_gpt":0.25157189567701177,"score_spread":0.2374348643110434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319166193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98247033,0.0042993445,0.0007756725,0.006979329,0.0005386261,0.0011254086,0.000021180425,0.00035465133,0.0034354595],"genre_scores_gemma":[0.9953088,0.0017982951,0.00012962273,0.0013828665,0.00013060174,0.00010345799,0.000035266432,0.00016346232,0.0009476156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99737674,0.00022528278,0.00048621272,0.0004667708,0.0008065513,0.0006384609],"domain_scores_gemma":[0.9977082,0.00020355846,0.00020785154,0.0015407974,0.00018957288,0.00015002638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006866305,0.00036379517,0.00043301028,0.00014583644,0.0003606698,0.00005969101,0.0006070771,0.00022819289,0.00012538525],"category_scores_gemma":[0.00019444521,0.00021334077,0.00046879184,0.0011611034,0.00042410058,0.000058016452,0.0001603899,0.0005631321,0.000247086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040368855,0.000109051645,0.0002917942,0.000026555901,0.00054806634,0.0001568314,0.000922397,0.0001322187,0.92792344,0.0018039604,0.0020386304,0.06564336],"study_design_scores_gemma":[0.002514564,0.00063019793,0.0057223886,0.00011294703,0.000087690976,0.000076208446,0.0005564103,0.00066136156,0.82327527,0.0014667542,0.16459034,0.0003058549],"about_ca_topic_score_codex":0.000054908178,"about_ca_topic_score_gemma":0.000006366107,"teacher_disagreement_score":0.16255172,"about_ca_system_score_codex":0.000100695375,"about_ca_system_score_gemma":0.0002100672,"threshold_uncertainty_score":0.8699784},"labels":[],"label_agreement":null},{"id":"W4320716983","doi":"10.1016/j.omtn.2023.02.010","title":"Discovery of DNA aptamers targeting SARS-CoV-2 nucleocapsid protein and protein-binding epitopes for label-free COVID-19 diagnostics","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Russian Academy of Sciences; Canadian Institutes of Health Research; Russian Science Foundation","keywords":"Aptamer; Systematic evolution of ligands by exponential enrichment; Immunogenicity; Epitope; Molecular biology; Chemistry; Target protein; RNA; DNA; Virology; Biology; Binding selectivity; Computational biology; Biochemistry; Immune system; Antibody; Gene; Genetics","score_opus":0.0208390383272459,"score_gpt":0.2984214093140673,"score_spread":0.27758237098682137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320716983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98392713,0.00076302537,0.012892032,0.0008650533,0.000043286644,0.0011758496,0.00015489677,0.00013575492,0.000042979078],"genre_scores_gemma":[0.9795932,0.0010155031,0.017860757,0.0007610556,0.00009528788,0.00014773553,0.00025884522,0.00009572815,0.00017190012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981069,0.00012286099,0.00041174484,0.00065695186,0.00024519733,0.00045635036],"domain_scores_gemma":[0.9988549,0.000044225944,0.00025964022,0.0006403604,0.00011417583,0.00008673634],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050435605,0.00034393233,0.00038477403,0.0001556385,0.0002084439,0.00006779612,0.00037866866,0.0002590131,7.146325e-7],"category_scores_gemma":[0.0009286235,0.00031191634,0.00020977297,0.0003547274,0.00031373938,0.000017862687,0.00025000618,0.00012372698,0.0000016275292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022753373,0.00007298806,0.00015689849,0.00009383842,0.00018044659,0.000017154502,0.00007187832,0.0000035988512,0.9940603,0.0002685191,0.0011450723,0.0037017858],"study_design_scores_gemma":[0.0011804805,0.00061889953,0.000023435725,0.00006021357,0.00003649349,0.0000045637285,0.00015128125,0.00011859645,0.9778635,0.0013993267,0.018147772,0.0003954629],"about_ca_topic_score_codex":0.000023241048,"about_ca_topic_score_gemma":0.0000080858,"teacher_disagreement_score":0.0170027,"about_ca_system_score_codex":0.000032540178,"about_ca_system_score_gemma":0.00008477429,"threshold_uncertainty_score":0.9999333},"labels":[],"label_agreement":null},{"id":"W4322504996","doi":"10.1016/j.omtn.2023.02.029","title":"Differential effects of SARM1 inhibition in traumatic glaucoma and EAE optic neuropathies","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; Child Health Research Institute, University of Nebraska Medical Center; National Institutes of Health; Ionis Pharmaceuticals; Stanford Maternal and Child Health Research Institute; Children's Health Research Institute; BrightFocus Foundation; Stanford University; Research to Prevent Blindness; Glaucoma Research Foundation","keywords":"Neuroprotection; Retinal ganglion cell; Optic nerve; Optic neuropathy; Optic neuritis; Medicine; Neuroscience; Axon; Pathology; Biology; Cell biology; Immunology; Multiple sclerosis","score_opus":0.0071739830006967865,"score_gpt":0.23322920816458792,"score_spread":0.22605522516389112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322504996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979348,0.0006076713,0.00018285302,0.0004293417,0.00010003629,0.00052934367,0.000001180661,0.00007884506,0.0001358927],"genre_scores_gemma":[0.9990942,0.00047785827,0.000077368386,0.00021349706,0.000016100625,0.000023514109,0.000017849574,0.00004110114,0.000038526738],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989374,0.00011459568,0.0002501238,0.00022634205,0.00023559197,0.00023593212],"domain_scores_gemma":[0.99957514,0.00006599374,0.00005656556,0.00020467052,0.000024847928,0.00007278927],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007059546,0.00017562008,0.00033691575,0.00025776052,0.000036097892,0.000013747051,0.000046979185,0.00009335075,0.000027540184],"category_scores_gemma":[0.00006139997,0.00014554222,0.00010445664,0.0004044364,0.00012909815,0.000037911916,0.00003455666,0.00016241852,0.000017022254],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000288647,0.0002373411,0.03307048,0.0005920609,0.000054942575,0.0008779018,0.001222795,9.777202e-7,0.95550185,0.00028181897,0.000026551286,0.007844621],"study_design_scores_gemma":[0.0040631983,0.0010379324,0.85437465,0.00039525473,0.00005311415,0.000078998324,0.00019781299,0.0009960168,0.13797739,0.00061653845,0.000047644386,0.00016145736],"about_ca_topic_score_codex":0.000023367555,"about_ca_topic_score_gemma":0.0000019173788,"teacher_disagreement_score":0.82130414,"about_ca_system_score_codex":0.000013117683,"about_ca_system_score_gemma":0.00001502857,"threshold_uncertainty_score":0.59350395},"labels":[],"label_agreement":null},{"id":"W4323664508","doi":"10.1016/j.omtn.2023.03.001","title":"Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Mesenchymal stem cell; Cell biology; Biology; microRNA; Microvesicles; Stem cell; Exosome; Cell; Extracellular matrix; Cell type; Stromal cell; Extracellular vesicle; Cancer research; Biochemistry; Gene","score_opus":0.03291951162477046,"score_gpt":0.2584070648892401,"score_spread":0.22548755326446962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4323664508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800855,0.016270272,0.0011356955,0.00030619348,0.00019927093,0.0016906661,0.000034558965,0.00011151674,0.00016634392],"genre_scores_gemma":[0.994736,0.00049309985,0.0026859138,0.00023294312,0.00025235213,0.00026995604,0.00019210509,0.00015041199,0.0009872154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99660814,0.0003967113,0.00073688244,0.0012044468,0.00038203638,0.00067178305],"domain_scores_gemma":[0.99836993,0.000025929292,0.00022291327,0.0010227597,0.00012118198,0.00023727756],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012264396,0.00043435837,0.00038519487,0.00014163285,0.00014745117,0.00007843994,0.00042458338,0.0003833569,0.000015939218],"category_scores_gemma":[0.00007917677,0.0004464229,0.00021095345,0.00050012855,0.00024269584,0.000019074945,0.00026162414,0.00033794527,0.00006770886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028192397,0.00029990097,0.014773215,0.00009496645,0.00007148166,0.00020901057,0.00007232723,0.0000582463,0.97842383,0.0003515227,0.00026224853,0.005101304],"study_design_scores_gemma":[0.0024611163,0.0004038724,0.011793957,0.000052515566,0.000022382148,0.000017045319,0.0001329604,0.00026672787,0.97479653,0.0010826818,0.008389518,0.00058066065],"about_ca_topic_score_codex":0.000007686516,"about_ca_topic_score_gemma":0.000004699907,"teacher_disagreement_score":0.015777173,"about_ca_system_score_codex":0.000039825354,"about_ca_system_score_gemma":0.000169653,"threshold_uncertainty_score":0.9997988},"labels":[],"label_agreement":null},{"id":"W4324342827","doi":"10.1016/j.omtn.2023.03.004","title":"Distinct regulatory functions and biological roles of lncRNA splice variants","year":2023,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Alternative splicing; Computational biology; Biology; RNA splicing; splice; Gene; Exon; RNA; Genetics; Transcriptome; Gene expression","score_opus":0.04104012963311125,"score_gpt":0.3192166060034307,"score_spread":0.27817647637031945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4324342827","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0048803743,0.9891379,0.0038932008,0.000024624469,0.00023179255,0.0010857858,0.00023114662,0.0000755527,0.00043961432],"genre_scores_gemma":[0.002104924,0.99553365,0.00022680916,0.00006787231,0.00020778656,0.00020940065,0.00068304373,0.0002513516,0.00071519054],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99651784,0.00051618845,0.00074118463,0.001173936,0.00044585488,0.00060498447],"domain_scores_gemma":[0.9979022,0.000049261842,0.000369125,0.0012924667,0.0001520837,0.00023483073],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055924157,0.00069530285,0.0012775516,0.0002801079,0.00015224048,0.000038464812,0.00068779476,0.0011609219,0.00008285802],"category_scores_gemma":[0.00015777662,0.0005969542,0.00072579295,0.0005659747,0.00045510812,0.000005242577,0.0005656794,0.0005399993,0.000074900105],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018622164,0.0001973114,0.000005346131,0.0020039633,0.0021326428,0.00011881161,0.000041680447,0.000008752086,0.13766213,0.00041728484,0.0008717643,0.8563541],"study_design_scores_gemma":[0.000847917,0.00083531917,0.00005198015,0.0013544747,0.00029685162,0.00014623266,0.000050894145,0.00001455562,0.006096277,0.00016876438,0.9893071,0.000829652],"about_ca_topic_score_codex":0.000020072066,"about_ca_topic_score_gemma":0.000010327861,"teacher_disagreement_score":0.9884353,"about_ca_system_score_codex":0.000060886956,"about_ca_system_score_gemma":0.0003383465,"threshold_uncertainty_score":0.9996482},"labels":[],"label_agreement":null},{"id":"W4360874519","doi":"10.1016/j.omtn.2023.03.015","title":"Development of DNA aptamers for visualization of glial brain tumors and detection of circulating tumor cells","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"NIH Clinical Center; Natural Sciences and Engineering Research Council of Canada; Ministry of Health of the Russian Federation; University of Ottawa; Ministry of Education and Science of the Russian Federation; Russian Foundation for Basic Research; Tomsk State University","keywords":"Aptamer; In vivo; Glioma; Ex vivo; Biology; Molecular biology; Brain tumor; DNA; Fluorescence microscope; Cancer research; Chemistry; Computational biology; Pathology; Fluorescence; Biochemistry; Medicine; Genetics","score_opus":0.011235855820749627,"score_gpt":0.27401442113729957,"score_spread":0.2627785653165499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360874519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95902205,0.00006753889,0.040614553,0.000013217588,0.00002293375,0.00021139013,0.000012236792,0.000022578615,0.000013484614],"genre_scores_gemma":[0.9891612,0.00004384544,0.010620061,0.000045811325,0.000016289867,0.000009209705,0.000065823486,0.000025917965,0.000011857989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910516,0.00004178709,0.0003577965,0.00022874086,0.0001329823,0.00013356366],"domain_scores_gemma":[0.99940085,0.000013082786,0.00026596364,0.00016668973,0.00012610377,0.00002731725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002687965,0.00012415311,0.00021451892,0.00011136,0.00004672356,0.0000042886977,0.0000763982,0.00008375112,5.5100634e-7],"category_scores_gemma":[0.000051262316,0.00011948795,0.000105309075,0.00024031449,0.00009948718,0.0000034898237,0.000039241164,0.000025576195,1.2072334e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010284415,0.000029294504,0.00009779651,0.00005285988,0.00008027445,7.1810473e-7,0.00014538827,0.000018955916,0.97568583,0.000025454323,0.000005341059,0.023755264],"study_design_scores_gemma":[0.00041770336,0.00027110157,0.0004389463,0.000032068652,0.000014983833,0.0000020417058,0.0001578505,0.0005971077,0.99715275,0.00007144257,0.0007208264,0.00012320477],"about_ca_topic_score_codex":0.0000037281952,"about_ca_topic_score_gemma":0.0000031415282,"teacher_disagreement_score":0.030139117,"about_ca_system_score_codex":0.0000089575005,"about_ca_system_score_gemma":0.000034106048,"threshold_uncertainty_score":0.48725775},"labels":[],"label_agreement":null},{"id":"W4379276529","doi":"10.1016/j.omtn.2023.05.012","title":"All roads lead to cure: Diversity of oligonucleotides in DM1 therapy","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Narodowym Centrum Nauki; Narodowe Centrum Nauki; Agencja Badań Medycznych; Canadian Association of Gastroenterology","keywords":"RNA; Oligonucleotide; Computational biology; RNase H; microRNA; Biology; Messenger RNA; Genetics; DNA; Nucleic acid; RNase P; Gene","score_opus":0.04936872590522342,"score_gpt":0.28660322044609926,"score_spread":0.23723449454087583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379276529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966417,0.00018655857,0.00019680144,0.0014754508,0.0002109884,0.0006400661,0.000034243858,0.0001722602,0.00044192438],"genre_scores_gemma":[0.99201787,0.0010840913,0.00021816469,0.006398366,0.000029213259,0.000036318666,0.000005770214,0.00006909099,0.00014114733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973444,0.00040511976,0.0003269572,0.0007534564,0.00061803655,0.0005520428],"domain_scores_gemma":[0.99888515,0.0000901211,0.00009563969,0.00069075904,0.00006194816,0.00017636169],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022176573,0.00031775027,0.0003464414,0.00037372796,0.00014660179,0.000043854412,0.0008772063,0.00008417873,0.000116569674],"category_scores_gemma":[0.00015204634,0.0003083816,0.00019701173,0.0013599332,0.00017685075,0.00010533828,0.0004342717,0.00016240454,0.0002919517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020081745,0.00020909688,0.010502858,0.000005878562,0.000018020088,0.00011738882,0.0011924033,0.0013975183,0.977476,0.0003793372,0.0006415141,0.0078591835],"study_design_scores_gemma":[0.001140402,0.00031498546,0.057781935,0.000012896904,0.0000049054383,0.000002361504,0.000069185364,0.0002140104,0.93507886,0.00067155523,0.004419264,0.0002896657],"about_ca_topic_score_codex":0.00008779082,"about_ca_topic_score_gemma":0.000008765046,"teacher_disagreement_score":0.047279075,"about_ca_system_score_codex":0.000042426323,"about_ca_system_score_gemma":0.000047036057,"threshold_uncertainty_score":0.9999368},"labels":[],"label_agreement":null},{"id":"W4384297217","doi":"10.1016/j.omtn.2023.07.015","title":"RGC-specific ATF4 and/or CHOP deletion rescues glaucomatous neurodegeneration and visual function","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Eye Institute; National Cancer Institute; National Institutes of Health; Natural Science Foundation of Hunan Province; National Natural Science Foundation of China; Children's Health Research Institute; Stanford University; National Institute on Aging; Research to Prevent Blindness; Glaucoma Research Foundation","keywords":"Unfolded protein response; CHOP; Retinal ganglion cell; Neurodegeneration; Neuroprotection; Biology; Cell biology; Endoplasmic reticulum; Optic nerve; Cancer research; Medicine; Neuroscience; Pathology","score_opus":0.010226856854818556,"score_gpt":0.24525738001881897,"score_spread":0.23503052316400042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384297217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929881,0.0029972964,0.0031371384,0.00024270892,0.00016359088,0.00024501898,0.000011234954,0.00008319287,0.00013171564],"genre_scores_gemma":[0.9908031,0.007731922,0.00014389327,0.0005968713,0.00016564228,0.00004528701,0.00022893105,0.00005107552,0.0002332801],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998765,0.00010497268,0.00019643102,0.00049974787,0.0001782783,0.00025559418],"domain_scores_gemma":[0.9995022,0.00000959885,0.000057627676,0.0002460366,0.000054394666,0.00013014181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118370604,0.00021695651,0.00014881455,0.000080147685,0.00017194012,0.000096366304,0.000077442135,0.00014994941,0.00002654313],"category_scores_gemma":[0.000025440368,0.00018743814,0.000069652546,0.00016544746,0.00009435523,0.000011740435,0.000081050704,0.00007825326,0.00001896798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006825513,0.0000528601,0.002827551,0.000017484204,0.000047184756,0.000036760248,0.000041266005,0.000035236357,0.9650722,0.00021527937,0.0011702594,0.02980134],"study_design_scores_gemma":[0.006132056,0.0032362253,0.12339298,0.00005636553,0.00008401933,0.00014835323,0.00032810136,0.005491823,0.72141355,0.0006400223,0.13785577,0.0012207279],"about_ca_topic_score_codex":0.0000096747235,"about_ca_topic_score_gemma":0.000005267871,"teacher_disagreement_score":0.24365866,"about_ca_system_score_codex":0.000008491986,"about_ca_system_score_gemma":0.000023474096,"threshold_uncertainty_score":0.76435053},"labels":[],"label_agreement":null},{"id":"W4384297244","doi":"10.1016/j.omtn.2023.07.016","title":"VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; National Institutes of Health; CHEO Research Institute","keywords":"Ependyma; Secretion; Cell biology; Cancer research; Chemistry; Biology; Medicine; Internal medicine; Central nervous system","score_opus":0.013938496683164343,"score_gpt":0.25212836624570373,"score_spread":0.23818986956253937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384297244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874293,0.0008016829,0.0012300124,0.0063058375,0.00014091855,0.0015380319,0.0000037028467,0.000514177,0.0020363415],"genre_scores_gemma":[0.99248064,0.00014289428,0.00049460673,0.0050678193,0.00013417621,0.00032497858,0.00011767571,0.00009252066,0.0011447015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979685,0.00030419155,0.00031913124,0.00044621216,0.00052144413,0.00044053255],"domain_scores_gemma":[0.99876803,0.00006717254,0.000105774736,0.0007591895,0.00012686993,0.00017298339],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047353053,0.0003225803,0.00037157402,0.00017934518,0.00025171277,0.00008083112,0.00023530939,0.0001755546,0.0008166884],"category_scores_gemma":[0.00012121315,0.0002109743,0.00024323899,0.0006606542,0.0002164608,0.000100810794,0.000060942308,0.0002911329,0.0006674201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036739057,0.00011676563,0.0014201982,0.000036465903,0.00029202132,0.000067646215,0.001589041,0.000004270528,0.9717581,0.00046177334,0.00020869014,0.023677623],"study_design_scores_gemma":[0.00628759,0.0013853285,0.053521477,0.00021634526,0.00016425631,0.000042640193,0.000899441,0.003054063,0.88381165,0.0063773757,0.043654304,0.0005855236],"about_ca_topic_score_codex":0.00007192625,"about_ca_topic_score_gemma":0.0000017383154,"teacher_disagreement_score":0.08794646,"about_ca_system_score_codex":0.00006854799,"about_ca_system_score_gemma":0.00010299091,"threshold_uncertainty_score":0.89421654},"labels":[],"label_agreement":null},{"id":"W4384564941","doi":"10.1016/j.omtn.2023.07.003","title":"DNM2 levels normalization improves muscle phenotypes of a novel mouse model for moderate centronuclear myopathy","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"PHENOMIN; Institut de Myologie; Radboud Universitair Medisch Centrum; Centre National de la Recherche Scientifique; Radboud Universiteit; Université de Strasbourg; Institute of Genetics; Laboratoire d'Excellence INRT; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Normalization (sociology); Phenotype; Myopathy; Medicine; Neuroscience; Biology; Internal medicine; Genetics","score_opus":0.04793237506614926,"score_gpt":0.27291514042587167,"score_spread":0.22498276535972242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384564941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.824801,0.000049331422,0.17352267,0.00016624891,0.00010522536,0.0007524773,0.00033774952,0.00019598864,0.00006927092],"genre_scores_gemma":[0.9948239,0.00009899143,0.0028370656,0.0014816234,0.000035910747,0.000110197914,0.00002695066,0.00014748376,0.00043793206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978751,0.000113691516,0.0003806551,0.00068613724,0.00042623346,0.0005182169],"domain_scores_gemma":[0.9989088,0.00006604494,0.00017993705,0.00055566843,0.00015911617,0.00013043852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001480397,0.0003140955,0.000302309,0.00017695432,0.00021233638,0.000078890414,0.00045552594,0.00009073992,0.000023780687],"category_scores_gemma":[0.0002035899,0.0003095981,0.00021356912,0.0004600028,0.00014512989,0.00018582067,0.00011423786,0.00009043677,0.000025282325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002278813,0.00023124943,0.000012602504,0.000029468325,0.000015573534,0.000002174479,0.0006716408,0.08844032,0.9047803,0.0030217604,0.00005982674,0.0025071804],"study_design_scores_gemma":[0.0011509751,0.0001471958,0.00021029197,0.0000054348934,0.0000113739925,4.572799e-7,0.000028185459,0.4159129,0.5816785,0.0005550497,0.00011717185,0.00018246658],"about_ca_topic_score_codex":0.0000059573827,"about_ca_topic_score_gemma":0.0000011629315,"teacher_disagreement_score":0.3274726,"about_ca_system_score_codex":0.000028560402,"about_ca_system_score_gemma":0.000089370595,"threshold_uncertainty_score":0.9999356},"labels":[],"label_agreement":null},{"id":"W4387063536","doi":"10.1016/j.omtn.2023.102040","title":"CRISPR-Cas9 delivery strategies with engineered extracellular vesicles","year":2023,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; China Scholarship Council","keywords":"CRISPR; Genome editing; Cas9; Microvesicles; Biology; Cell biology; Extracellular vesicles; Computational biology; Extracellular vesicle; Cell; Genetic enhancement; Gene; microRNA; Genetics","score_opus":0.025460391390093682,"score_gpt":0.2867942929540549,"score_spread":0.2613339015639612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387063536","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009899959,0.9825271,0.0052213734,0.000021167521,0.00022854985,0.0013676768,0.00013806188,0.00026567,0.0003304908],"genre_scores_gemma":[0.0034420365,0.991122,0.0015551093,0.00011263788,0.0003970828,0.00032717813,0.0012237506,0.0007457408,0.001074445],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9956255,0.00043044687,0.0008889919,0.0014940274,0.00061612536,0.00094490487],"domain_scores_gemma":[0.99691564,0.000047369995,0.00043562127,0.0020770559,0.00016466972,0.0003596554],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00038443418,0.0013180582,0.0014829565,0.00027917977,0.00018211485,0.0002790577,0.0013424816,0.0009777161,0.00009209311],"category_scores_gemma":[0.000047019672,0.001129892,0.0010479649,0.0006007725,0.00032989623,0.000021723332,0.00029647388,0.0006105006,0.00034497006],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040514796,0.0006136096,0.0000105070985,0.008589075,0.0051010526,0.0031998677,0.0001402647,0.00026896672,0.17514305,0.0011937466,0.002397919,0.8029368],"study_design_scores_gemma":[0.00092876796,0.000564883,0.0000050327885,0.001845678,0.00066584547,0.00014477785,0.000119425575,0.000021101738,0.012924953,0.00014042089,0.98105323,0.0015858554],"about_ca_topic_score_codex":0.000013888973,"about_ca_topic_score_gemma":0.0000051710995,"teacher_disagreement_score":0.97865534,"about_ca_system_score_codex":0.000076167984,"about_ca_system_score_gemma":0.0007181815,"threshold_uncertainty_score":0.9999571},"labels":[],"label_agreement":null},{"id":"W4388011859","doi":"10.1016/j.omtn.2023.102066","title":"Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi","year":2023,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"European Regional Development Fund; Novo Nordisk Fonden; Consejería de Salud y Consumo, Junta de Andalucía; Junta de Andalucía; Lundbeckfonden; Consejería de Transformación Económica, Industria, Conocimiento y Universidades; Consejería de Salud y Familias, Junta de Andalucía; Steno Diabetes Center Aarhus; European Cooperation in Science and Technology","keywords":"Harmonization; Genome editing; Action (physics); Business; Engineering ethics; Knowledge management; Political science; Biotechnology; Genome; Computer science; Gene; Biology; Engineering; Genetics","score_opus":0.03568538218232281,"score_gpt":0.3714595403355327,"score_spread":0.3357741581532099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388011859","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06766096,0.92315364,0.007451358,0.000011000939,0.00014448285,0.0013793502,0.0001351125,0.000039698418,0.000024427818],"genre_scores_gemma":[0.034679282,0.96237934,0.0010073078,0.000019556852,0.00043539063,0.00026320247,0.0009283815,0.00020935066,0.00007820557],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998475,0.000050120278,0.0005040672,0.0005006674,0.00020991912,0.0002602311],"domain_scores_gemma":[0.9991339,0.0000076637025,0.00027111592,0.0003451743,0.00012080956,0.000121350124],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012565496,0.00037468295,0.0006969202,0.00018514924,0.00007124954,0.000030906394,0.00023063949,0.00021581443,0.000005739559],"category_scores_gemma":[0.000027920696,0.00036084323,0.00023975057,0.0003205497,0.00007190815,0.000005068929,0.0001072091,0.000102920305,0.0000018049527],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024600478,0.00007665081,0.00024480335,0.005728736,0.00037822037,0.0000088946845,0.00011410673,0.00009283271,0.4196294,0.000016302873,0.00008345502,0.57360196],"study_design_scores_gemma":[0.0011212467,0.0008122122,0.0002382127,0.0033198441,0.00085864065,0.000046919373,0.00015602892,0.00006329292,0.8581981,0.000022047521,0.13413711,0.0010263253],"about_ca_topic_score_codex":0.000007775696,"about_ca_topic_score_gemma":0.000001034505,"teacher_disagreement_score":0.5725757,"about_ca_system_score_codex":0.000026327918,"about_ca_system_score_gemma":0.000059484264,"threshold_uncertainty_score":0.99988437},"labels":[],"label_agreement":null},{"id":"W4388570138","doi":"10.1016/j.omtn.2023.102073","title":"A bimolecular modification strategy for developing long-lasting bone anabolic aptamer","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"National Key Research and Development Program of China; Young Scientists Fund; Science, Technology and Innovation Commission of Shenzhen Municipality; Hunan Provincial Science and Technology Department; National Natural Science Foundation of China; Basic and Applied Basic Research Foundation of Guangdong Province; Chinese University of Hong Kong; Natural Science Foundation for Young Scientists of Shanxi Province; Hong Kong Baptist University","keywords":"Aptamer; Chemistry; Anabolism; Human serum albumin; Conjugate; Druggability; Conjugated system; Anabolic Agents; Biochemistry; Pharmacology; Biophysics; Molecular biology; Biology","score_opus":0.03461209334631472,"score_gpt":0.3198367122384272,"score_spread":0.2852246188921125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388570138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.801222,0.00074860995,0.19683053,0.0003328055,0.000056935296,0.00043758267,0.000017857104,0.00023898686,0.00011464182],"genre_scores_gemma":[0.98291135,0.00077521574,0.014404099,0.000754506,0.00014767065,0.00009664975,0.0005509007,0.00009975156,0.00025985576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981052,0.00008723009,0.00036632296,0.0006962938,0.00022944753,0.0005154569],"domain_scores_gemma":[0.99893594,0.000014082206,0.00016772281,0.0005804275,0.0002171183,0.00008471005],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034405306,0.00032766117,0.0002839942,0.0002018495,0.00021842735,0.000070727794,0.00026806697,0.0002553502,0.0000018360824],"category_scores_gemma":[0.00008382373,0.00031329136,0.0002701713,0.000629392,0.00011205865,0.00000941094,0.00008552855,0.000109247856,0.000014635034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088396046,0.00003359417,0.0002012026,0.000016353071,0.00012726759,0.000022303366,0.000021485432,0.0002438946,0.959703,0.00032421522,0.00018808711,0.03903018],"study_design_scores_gemma":[0.000717287,0.00029441377,0.0013955686,0.000028731047,0.000033643253,0.000022748232,0.00005634249,0.0017674575,0.9827029,0.0007425574,0.011734523,0.00050383736],"about_ca_topic_score_codex":0.0000103208195,"about_ca_topic_score_gemma":0.000006073384,"teacher_disagreement_score":0.18242642,"about_ca_system_score_codex":0.000032238266,"about_ca_system_score_gemma":0.00008025792,"threshold_uncertainty_score":0.99993193},"labels":[],"label_agreement":null},{"id":"W4388776339","doi":"10.1016/j.omtn.2023.102080","title":"Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity","year":2023,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; University of Massachusetts Medical School; National Institutes of Health; Canada Research Chairs; Canada Foundation for Innovation; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Aldeyra Therapeutics; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec; Centre québécois sur les matériaux fonctionnels","keywords":"Conjugate; Oligonucleotide; Drug delivery; In vivo; Small interfering RNA; Nucleic acid; Chemistry; Amphiphile; Gene silencing; Drug carrier; Albumin; Gene delivery; Serum albumin; Pharmacology; Biophysics; Biochemistry; Biology; RNA; Transfection; Gene","score_opus":0.010196274190834706,"score_gpt":0.24908835032428184,"score_spread":0.23889207613344712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388776339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997972,0.0007895511,0.00015723999,0.00024191043,0.00011515846,0.00030656438,0.000019076155,0.000049978127,0.0003485343],"genre_scores_gemma":[0.99733245,0.0011883172,0.00006180459,0.00071830465,0.00008114192,0.00004162969,0.00005004457,0.0000535139,0.0004727867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838704,0.000121562705,0.0002467512,0.00059500424,0.00017751497,0.00047213412],"domain_scores_gemma":[0.9993727,0.00002047958,0.000058306683,0.00037932306,0.00005877246,0.00011037407],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021464232,0.0002741894,0.0002434581,0.0001911982,0.0000908896,0.000051756047,0.000280192,0.0002416289,0.000044754175],"category_scores_gemma":[0.00006055049,0.0002766834,0.00010577685,0.0004239986,0.00013061044,0.000009231804,0.00013828246,0.00016988425,0.000070631664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015221289,0.00009474393,0.0031091839,0.000010864663,0.0000846043,0.00007190542,0.00018473205,0.000049562972,0.9921287,0.00003820494,0.0009797729,0.0030955304],"study_design_scores_gemma":[0.0015736285,0.00067515566,0.009177581,0.00004095498,0.000009985766,0.000027986624,0.00009638682,0.00016889056,0.9845021,0.00018354056,0.003174273,0.00036955267],"about_ca_topic_score_codex":0.000039078754,"about_ca_topic_score_gemma":0.000048067886,"teacher_disagreement_score":0.007626618,"about_ca_system_score_codex":0.000030255069,"about_ca_system_score_gemma":0.000053573352,"threshold_uncertainty_score":0.9999685},"labels":[],"label_agreement":null},{"id":"W4391365356","doi":"10.1016/j.omtn.2024.102130","title":"A pipeline for identifying guide RNA sequences that promote RNA editing of nonsense mutations that cause inherited retinal diseases","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Israel Science Foundation; Geothermal Technologies Program; Bar-Ilan University; Foundation Fighting Blindness","keywords":"Nonsense; RNA editing; Genetics; Nonsense mutation; RNA; Pipeline (software); Biology; Computational biology; Retinal; Mutation; Gene; Computer science; Missense mutation","score_opus":0.032855282144900355,"score_gpt":0.31516306520103693,"score_spread":0.2823077830561366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391365356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94745666,0.0061283167,0.044340502,0.00066042464,0.00033099513,0.0005775634,0.00019632932,0.00008523475,0.00022394805],"genre_scores_gemma":[0.9951411,0.0002496716,0.0025823067,0.00040681075,0.00027697496,0.00008130319,0.0005297095,0.0000731326,0.0006589992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984635,0.00010790621,0.0003437349,0.0004951983,0.00029634108,0.00029331353],"domain_scores_gemma":[0.99911356,0.000029483084,0.00014072352,0.0003984479,0.00016236711,0.00015541806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021143995,0.0002553328,0.00021218708,0.00011991123,0.0001410528,0.00013408496,0.00021595063,0.00013286366,0.00005882762],"category_scores_gemma":[0.00013121813,0.00023731415,0.000316464,0.00020355063,0.0001752384,0.000022359389,0.000059955044,0.00007981725,0.000005788047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022683627,0.00008988779,0.00093351596,0.00013506996,0.00020961532,0.000081382845,0.00028266516,0.0001844185,0.98504585,0.00015455547,0.0019514593,0.010704738],"study_design_scores_gemma":[0.0018156099,0.0003056435,0.0033572402,0.0002900306,0.00022699432,0.000056109195,0.0006682249,0.0074533643,0.95279384,0.0012045528,0.031249166,0.00057923334],"about_ca_topic_score_codex":0.000019443345,"about_ca_topic_score_gemma":0.000005160594,"teacher_disagreement_score":0.047684405,"about_ca_system_score_codex":0.00002436097,"about_ca_system_score_gemma":0.0001518303,"threshold_uncertainty_score":0.96773905},"labels":[],"label_agreement":null},{"id":"W4392907550","doi":"10.1016/j.omtn.2024.102175","title":"Physiologically based modeling of LNP-mediated delivery of mRNA in the vascular system","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Heart, Lung, and Blood Institute; Advanced Research Projects Agency; Defense Advanced Research Projects Agency; National Institutes of Health","keywords":"Pharmacodynamics; Messenger RNA; Pharmacology; Luciferase; RNA; Pharmacokinetics; Kinetics; Cell biology; Chemistry; Medicine; Biology; Computational biology; Biochemistry; Transfection; Gene","score_opus":0.012626917330060435,"score_gpt":0.22932491108157663,"score_spread":0.2166979937515162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392907550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98365414,0.007330087,0.008148698,0.00006120259,0.00009158387,0.00025107744,0.000021271331,0.00002114925,0.00042080323],"genre_scores_gemma":[0.9984548,0.0006707793,0.0002957073,0.0003863927,0.00004534901,0.000028467217,0.000082084756,0.000028977815,0.0000074328464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985421,0.00021869563,0.0003938503,0.0003645715,0.0002551268,0.00022569089],"domain_scores_gemma":[0.9992256,0.00002631759,0.00006886725,0.0005312022,0.00011507675,0.000032934455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040189773,0.00020577213,0.00026915048,0.00010104753,0.000027535274,0.000021687158,0.0004956818,0.00019515347,0.000017961593],"category_scores_gemma":[0.000021270635,0.00014274062,0.00031612997,0.00025823645,0.000088810695,0.000006123469,0.000054785083,0.00014215651,0.000009781081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014886736,0.00008763467,0.00013024977,0.00009536405,0.00014572966,0.000030234129,0.00012269909,0.005963166,0.99111253,0.00012730957,0.000047411395,0.001988795],"study_design_scores_gemma":[0.0015326181,0.0016412109,0.0011665801,0.00046647064,0.00007036284,0.000014507437,0.0008227075,0.17596541,0.81572396,0.00015758588,0.0019277033,0.0005108921],"about_ca_topic_score_codex":0.00007227952,"about_ca_topic_score_gemma":0.0000034252935,"teacher_disagreement_score":0.17538859,"about_ca_system_score_codex":0.000015414422,"about_ca_system_score_gemma":0.00008995722,"threshold_uncertainty_score":0.58207935},"labels":[],"label_agreement":null},{"id":"W4399284751","doi":"10.1016/j.omtn.2024.102234","title":"CircHTT(2,3,4,5,6) — co-evolving with the HTT CAG-repeat tract — modulates Huntington's disease phenotypes","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Real-time simulation and control systems","field":"Engineering","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; HORIZON EUROPE Framework Programme; Università degli Studi di Trento; Horizon 2020 Framework Programme; European Huntington's Disease Network; Hereditary Disease Foundation; Huntington Society of Canada; Cancer Prevention and Research Institute of Texas; European Molecular Biology Organization; European Regional Development Fund; European Commission; Pfizer; National Institutes of Health","keywords":"Huntington's disease; Polyglutamine tract; Phenotype; Disease; Biology; Genetics; Neuroscience; Huntingtin; Medicine; Internal medicine; Gene","score_opus":0.005476684548015145,"score_gpt":0.21129925917481376,"score_spread":0.20582257462679862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399284751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95339495,0.012053609,0.021710563,0.00084800704,0.00035678857,0.00068742596,0.000016248012,0.0013596305,0.009572791],"genre_scores_gemma":[0.99864817,0.000112248024,0.000087401466,0.00028780993,0.0002035846,0.000061593295,0.000024540974,0.00017221378,0.00040245912],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99843544,0.00009572672,0.00026353323,0.00037579468,0.00041334968,0.00041614042],"domain_scores_gemma":[0.99908864,0.00008941992,0.00003670525,0.00057129964,0.000054025615,0.00015992335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023401233,0.00035813666,0.00027557425,0.00010940275,0.00016807608,0.0005225461,0.00031525042,0.00009164192,0.0003100757],"category_scores_gemma":[0.000011887363,0.00024162901,0.00020190839,0.00030721325,0.000075328164,0.00027262655,0.000016861255,0.0002743291,0.00020488181],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029271145,0.00017771978,0.003883096,0.0004823957,0.0021264765,0.00055565784,0.00457243,0.47919047,0.36272913,0.0038791487,0.0036633092,0.13844743],"study_design_scores_gemma":[0.001647918,0.00015240572,0.012806384,0.00029513327,0.00016471422,0.00002442852,0.00029584634,0.8669847,0.010898924,0.0004762186,0.10515202,0.0011012706],"about_ca_topic_score_codex":0.00003495989,"about_ca_topic_score_gemma":0.0000022360753,"teacher_disagreement_score":0.38779426,"about_ca_system_score_codex":0.00007344584,"about_ca_system_score_gemma":0.00003959488,"threshold_uncertainty_score":0.9853345},"labels":[],"label_agreement":null},{"id":"W4399555205","doi":"10.1016/j.omtn.2024.102248","title":"Evaluation of DNA minicircles for delivery of adenine and cytosine base editors using activatable gene on “GO” reporter imaging systems","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Minicircle; Cytosine; CRISPR; Cytosine deaminase; DNA; Gene delivery; Biology; Enhancer; Computational biology; Reporter gene; Cas9; Thymine; Plasmid; Gene; Genetic enhancement; Genetics","score_opus":0.019423394366986008,"score_gpt":0.311431732164499,"score_spread":0.292008337797513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399555205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9470504,0.01239557,0.039526735,0.000033174932,0.0005433784,0.00037241788,0.00003515229,0.000011555908,0.000031598374],"genre_scores_gemma":[0.9978683,0.00014834333,0.0014143019,0.000026409207,0.00040586138,0.000024717221,0.000049106045,0.000046799447,0.000016151156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988986,0.0000549222,0.00029017212,0.00031655273,0.0002842599,0.00015548876],"domain_scores_gemma":[0.99934876,0.000017467244,0.000083167106,0.00029849674,0.00021140542,0.00004073282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005771129,0.00015405974,0.00018679033,0.00009153412,0.000029541206,0.000022570268,0.000077796976,0.00008501092,0.0000059541658],"category_scores_gemma":[0.000045220644,0.00014956675,0.00009942672,0.00008822877,0.000038708018,0.0000057698344,0.000032126376,0.000041451098,2.147532e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007952006,0.00003188639,0.00009772458,0.000097470474,0.00017385939,0.00000445266,0.00004993755,0.00618938,0.98361725,0.000008821097,0.00017264429,0.009477077],"study_design_scores_gemma":[0.000641859,0.00021235124,0.000159873,0.00011412217,0.00012490936,0.000029003175,0.00005898588,0.062155794,0.93434924,0.000019635892,0.0019896885,0.00014452264],"about_ca_topic_score_codex":0.000018938936,"about_ca_topic_score_gemma":5.697461e-7,"teacher_disagreement_score":0.055966415,"about_ca_system_score_codex":0.000023372224,"about_ca_system_score_gemma":0.00007881457,"threshold_uncertainty_score":0.6099155},"labels":[],"label_agreement":null},{"id":"W4399699980","doi":"10.1016/j.omtn.2024.102251","title":"Selection of DNA aptamers that prevent the fibrillization of α-synuclein protein in cellular and mouse models","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; Carleton University; Canadian Institutes of Health Research; University of Ottawa; University of Calgary; Michael J. Fox Foundation for Parkinson's Research","keywords":"Aptamer; Selection (genetic algorithm); DNA; Computational biology; Biology; Cell biology; Genetics; Computer science; Artificial intelligence","score_opus":0.015204300251815503,"score_gpt":0.23913553052610975,"score_spread":0.22393123027429424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399699980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990952,0.0026779268,0.0050350307,0.00019814228,0.00002689846,0.0009263791,0.000010971425,0.00003684264,0.000135792],"genre_scores_gemma":[0.998667,0.00044537382,0.0005596538,0.000060099228,0.00001079022,0.00005215914,0.000016627544,0.000042717133,0.0001455977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902034,0.00009188366,0.0002106676,0.00025712547,0.0002706838,0.00014930345],"domain_scores_gemma":[0.9996161,0.000010583298,0.00006748929,0.00021486248,0.000036371883,0.000054583914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016081665,0.00015618878,0.00023588316,0.00013738527,0.00002896771,0.000016348062,0.00006076873,0.00008047031,0.00004289427],"category_scores_gemma":[0.000006072402,0.0001111136,0.000107811364,0.00027344687,0.000060342583,0.00008560504,0.000022488504,0.00008426262,0.0000020512778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022195959,0.00023976299,0.00058030867,0.00015349363,0.00025540197,0.00003413182,0.0005720465,0.00012974511,0.9820124,0.0019153182,0.000007693751,0.013877756],"study_design_scores_gemma":[0.0010466102,0.0004147108,0.0008972619,0.0002268353,0.00008716785,0.00000818616,0.000087250635,0.019822044,0.97437066,0.0021069185,0.00083130534,0.00010106618],"about_ca_topic_score_codex":0.000050177394,"about_ca_topic_score_gemma":0.0000026690334,"teacher_disagreement_score":0.0196923,"about_ca_system_score_codex":0.000052626,"about_ca_system_score_gemma":0.00005302313,"threshold_uncertainty_score":0.4531081},"labels":[],"label_agreement":null},{"id":"W4400858554","doi":"10.1016/j.omtn.2024.102279","title":"The roles of CD4+ T cell help, sex, and dose in the induction of protective CD8+ T cells against a lethal poxvirus by mRNA-LNP vaccines","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Sidney Kimmel Comprehensive Cancer Center; National Institutes of Health; Thomas Jefferson University","keywords":"Virology; CD8; Cytotoxic T cell; Biology; Immunology; Immune system; In vitro; Genetics","score_opus":0.008380820738662783,"score_gpt":0.2410593032976553,"score_spread":0.2326784825589925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400858554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9600385,0.037870906,0.00009834612,0.0005195049,0.0001375304,0.00065802253,0.000051607578,0.000024019479,0.00060159614],"genre_scores_gemma":[0.9966362,0.0027783462,0.000015001095,0.00015140431,0.000023104147,0.00006351067,0.000016528988,0.000026264173,0.0002896234],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829495,0.0006660167,0.0002938177,0.0002908345,0.000107479085,0.00034690095],"domain_scores_gemma":[0.99932384,0.00017980601,0.00008569996,0.0003384709,0.000050792893,0.000021380343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007117752,0.00019953745,0.0002491768,0.00012124534,0.00014346481,0.00004095147,0.00038178804,0.00022277972,0.000031080777],"category_scores_gemma":[0.000028601762,0.00011578951,0.00011243781,0.0002888214,0.00034211614,0.00007548357,0.000081257866,0.0005269224,0.00002221672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003704179,0.00011379179,0.00007131615,0.000029865518,0.00015081423,0.000017586592,0.0025771856,0.0000043880373,0.9224282,0.00011399379,0.0004711265,0.07365133],"study_design_scores_gemma":[0.001092344,0.00041974272,0.00046126003,0.000039420727,0.000012820415,0.000020829988,0.0012972684,0.00001927241,0.96829355,0.00050081627,0.027719278,0.00012337066],"about_ca_topic_score_codex":0.00020221055,"about_ca_topic_score_gemma":0.000032233278,"teacher_disagreement_score":0.073527955,"about_ca_system_score_codex":0.00002421911,"about_ca_system_score_gemma":0.0000683753,"threshold_uncertainty_score":0.4721759},"labels":[],"label_agreement":null},{"id":"W4401198614","doi":"10.1016/j.omtn.2024.102290","title":"Enhancing peptide and PMO delivery to mouse airway epithelia by chemical conjugation with the amphiphilic peptide S10","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Feldan (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de Recherche du Québec - Santé; Institut sur la Nutrition et les Aliments Fonctionnels; Québec Consortium for Drug Discovery; Université Laval","keywords":"Peptide; Intracellular; Chemistry; Endosome; Oligonucleotide; Cell-penetrating peptide; Biophysics; PEGylation; Cell biology; Biochemistry; Biology","score_opus":0.004897716384228482,"score_gpt":0.21508380774393812,"score_spread":0.21018609135970964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401198614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98524415,0.004252568,0.008111593,0.0016574545,0.00006634629,0.0003390494,0.00003125344,0.00005194074,0.00024563336],"genre_scores_gemma":[0.9936387,0.0006975985,0.00045306399,0.0034643786,0.00013454375,0.00006506839,0.000094669005,0.00007294604,0.0013790135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855113,0.00007707831,0.00020934123,0.0006027157,0.00021925881,0.0003404508],"domain_scores_gemma":[0.9992548,0.000021072028,0.0000427334,0.00045874587,0.000090718444,0.00013187867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019359501,0.000301179,0.00018496678,0.00005667297,0.0001106375,0.00015223945,0.00029999326,0.00015944311,0.000042682812],"category_scores_gemma":[0.000017560671,0.00021387811,0.00010880859,0.00015685402,0.00014708767,0.000014704057,0.00011012227,0.00018705252,0.000070522685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020450566,0.00002719021,0.00008677235,0.000014955474,0.00015565289,0.000015211946,0.0003452264,0.00002001544,0.9880586,0.000043240158,0.0056191995,0.005409398],"study_design_scores_gemma":[0.0003611849,0.00057368504,0.000073301846,0.000048733134,0.000026114018,0.000034292818,0.00015605144,0.00007793258,0.9342813,0.000038997267,0.06402009,0.00030832682],"about_ca_topic_score_codex":0.00005498559,"about_ca_topic_score_gemma":0.000025256526,"teacher_disagreement_score":0.058400888,"about_ca_system_score_codex":0.000027160842,"about_ca_system_score_gemma":0.000052627853,"threshold_uncertainty_score":0.8721697},"labels":[],"label_agreement":null},{"id":"W4402014586","doi":"10.1016/j.omtn.2024.102296","title":"Breaking bad aggregates: How a DNA aptamer cleans up Parkinson’s disease","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Aptamer; Disease; DNA; Chemistry; Medicine; Biology; Internal medicine; Genetics; Biochemistry","score_opus":0.014670671505717419,"score_gpt":0.25948447918678985,"score_spread":0.24481380768107244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402014586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9618129,0.02623936,0.0039139455,0.0044346023,0.0007842581,0.00087358453,0.000097841854,0.00069187884,0.0011515986],"genre_scores_gemma":[0.9920914,0.0015912036,0.0006465438,0.0029105225,0.00021517539,0.00015318343,0.00011771871,0.00020960826,0.0020646292],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974506,0.000105902924,0.00025331156,0.00090800866,0.00063720293,0.0006449661],"domain_scores_gemma":[0.9983346,0.000030129326,0.00007052087,0.0008055994,0.00007277147,0.0006863825],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001508614,0.00052649033,0.0004604848,0.00025177278,0.00016429111,0.0002631158,0.00022319848,0.0001533358,0.0006037023],"category_scores_gemma":[0.000031154705,0.0004327095,0.0005782516,0.00044598524,0.00011012187,0.00018867996,0.000068048044,0.00027249972,0.00041593442],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031645484,0.0018775992,0.012975255,0.0005648194,0.0049996832,0.030238552,0.0020382295,0.000014999034,0.13501284,0.006253892,0.004601165,0.7982584],"study_design_scores_gemma":[0.0045122253,0.0005665624,0.023589125,0.0008457637,0.00076616334,0.00015516623,0.00016914589,0.00261124,0.022638282,0.0019211472,0.9414582,0.0007669367],"about_ca_topic_score_codex":0.000026367929,"about_ca_topic_score_gemma":0.000001958024,"teacher_disagreement_score":0.9368571,"about_ca_system_score_codex":0.00019247438,"about_ca_system_score_gemma":0.00020673666,"threshold_uncertainty_score":0.9998125},"labels":[],"label_agreement":null},{"id":"W4402969161","doi":"10.1016/j.omtn.2024.102349","title":"Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Domaine d’Intérêt Majeur Logiciels et Systèmes Complexes; Sorbonne Université; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; AFM-Téléthon; Association Française contre les Myopathies; Agence Nationale de la Recherche; Fondation Voir et Entendre; Foundation Fighting Blindness","keywords":"Cas9; CRISPR; Genome editing; Computational biology; Guide RNA; Computer science; RNA; Base (topology); Retina; Genome; Biology; Genetics; Gene; Neuroscience","score_opus":0.01028850280644513,"score_gpt":0.2708784636405886,"score_spread":0.2605899608341435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402969161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857402,0.008918841,0.0035680193,0.0002639884,0.0002488432,0.00038720667,0.000037324433,0.000023629702,0.00081195513],"genre_scores_gemma":[0.9964682,0.0006056208,0.0014994517,0.00022253272,0.00091415236,0.00004451619,0.000050762057,0.000043647597,0.0001511374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891114,0.00009250219,0.00025225832,0.00033070057,0.00017058878,0.00024282614],"domain_scores_gemma":[0.999528,0.0000231161,0.000036041532,0.00032768972,0.000040584604,0.000044556993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037314583,0.00018930573,0.00017147751,0.000066748384,0.000048534792,0.000049959654,0.00022279033,0.00010885717,0.000038114205],"category_scores_gemma":[0.000046004596,0.00013609942,0.00008375312,0.00016197105,0.000082438986,0.0000049277764,0.000075032855,0.00011358041,0.0000024540084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058013262,0.00002599604,0.00003820885,0.00007695538,0.00005321881,0.000076416334,0.0002627447,0.00014449579,0.99386346,0.00002491661,0.001224807,0.0041507585],"study_design_scores_gemma":[0.00049371686,0.0004031897,0.00063828623,0.00009374092,0.000017566666,0.000041103747,0.00036244583,0.0007078258,0.78988236,0.000027635948,0.2070817,0.0002504065],"about_ca_topic_score_codex":0.000057064215,"about_ca_topic_score_gemma":0.000016446902,"teacher_disagreement_score":0.20585689,"about_ca_system_score_codex":0.000012611776,"about_ca_system_score_gemma":0.000046011148,"threshold_uncertainty_score":0.5549973},"labels":[],"label_agreement":null},{"id":"W4403257590","doi":"10.1016/j.omtn.2024.102356","title":"Multi-gene duplication removal in an engineered human cellular MECP2 duplication syndrome model with an IRAK1-MECP2 duplication","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Rett Syndrome Research Trust","keywords":"Gene duplication; MECP2; Gene; Functional divergence; Data deduplication; Biology; Genetics; Computational biology; Computer science; Gene family; Genome; Phenotype; Computer security","score_opus":0.014060695299684267,"score_gpt":0.24858854770574215,"score_spread":0.2345278524060579,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403257590","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9334356,0.0012996334,0.064060576,0.0002388918,0.000050599472,0.0007143354,0.000020852574,0.00010271163,0.000076807555],"genre_scores_gemma":[0.9829754,0.0003381465,0.014333129,0.00037513435,0.000023170876,0.00021608066,0.0013832593,0.0001617117,0.00019391715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977391,0.00009364537,0.00039315948,0.0010893431,0.00028591312,0.00039886008],"domain_scores_gemma":[0.99859273,0.0000034538796,0.00008449108,0.0010178876,0.00009835312,0.00020309276],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022502129,0.00040408643,0.00023000244,0.00019164695,0.00013016017,0.00012587874,0.00046500002,0.00027392423,0.000017713608],"category_scores_gemma":[0.000008273463,0.0004055627,0.000097141776,0.00036413528,0.00007893488,0.000035272828,0.00006808369,0.00019053768,0.000019121475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000086237014,0.00030567357,0.00018628627,0.000023313709,0.000055068038,0.000042667736,0.00019994081,0.0065817274,0.9885642,0.00024206475,0.000016003381,0.0036968188],"study_design_scores_gemma":[0.0016468662,0.0011542495,0.015382618,0.000035905527,0.000034710887,0.00011745289,0.000067423585,0.10228979,0.87618965,0.00039865632,0.0018398594,0.0008428122],"about_ca_topic_score_codex":0.000026623493,"about_ca_topic_score_gemma":0.00003698784,"teacher_disagreement_score":0.112374544,"about_ca_system_score_codex":0.00006126192,"about_ca_system_score_gemma":0.000113619215,"threshold_uncertainty_score":0.9998396},"labels":[],"label_agreement":null},{"id":"W4404727663","doi":"10.1016/j.omtn.2024.102401","title":"Precise template-free correction restores gene function in Tay-Sachs disease while reframing is ineffective","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Sickkids Research Institute; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Frameshift mutation; Cognitive reframing; Gene; Genetics; Function (biology); Mutation; Biology; Psychology","score_opus":0.006467463506991458,"score_gpt":0.2634768283711169,"score_spread":0.25700936486412546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404727663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9258121,0.014324811,0.057802957,0.00014574939,0.0010875403,0.00038036966,0.00002487531,0.00009058389,0.0003309596],"genre_scores_gemma":[0.99761325,0.0007504104,0.00037998584,0.0002396077,0.00024335191,0.00009654833,0.000113372575,0.000087288405,0.00047620203],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985889,0.00008029721,0.00022955541,0.0006005662,0.00019973611,0.00030091126],"domain_scores_gemma":[0.99917835,0.0000163151,0.00003236499,0.00060606323,0.00004784752,0.00011905611],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019489447,0.00026768417,0.00016628293,0.00015849438,0.00006944453,0.000076972916,0.00020775328,0.00018813131,0.000057617857],"category_scores_gemma":[0.00005707903,0.00026924524,0.00015151738,0.00028737128,0.000044114513,0.000012846755,0.00009691283,0.00020739502,0.000022431781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005635466,0.000068927475,0.001598648,0.000040781364,0.00012383545,0.00006560189,0.00024553193,0.0022054715,0.9614172,0.000021504575,0.0030383002,0.03061064],"study_design_scores_gemma":[0.0012753838,0.00080184994,0.017361829,0.00014008342,0.000056173652,0.00002638748,0.00006892228,0.006044223,0.89431113,0.0004314059,0.07889795,0.00058463874],"about_ca_topic_score_codex":0.000046578505,"about_ca_topic_score_gemma":0.000017510856,"teacher_disagreement_score":0.07585965,"about_ca_system_score_codex":0.00006117203,"about_ca_system_score_gemma":0.000055218024,"threshold_uncertainty_score":0.999976},"labels":[],"label_agreement":null},{"id":"W4404727696","doi":"10.1016/j.omtn.2024.102402","title":"An mRNA vaccine induces antimycobacterial immunity by activating DNA damage repair and autophagy","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; Fudan University; National Natural Science Foundation of China","keywords":"Antimycobacterial; Autophagy; Immunity; DNA vaccination; Biology; DNA damage; Virology; DNA; Microbiology; Immunology; Immune system; Medicine; Tuberculosis; Genetics; Mycobacterium tuberculosis; Apoptosis; Immunization","score_opus":0.007651773201580437,"score_gpt":0.25246921489615765,"score_spread":0.2448174416945772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404727696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98557305,0.01185117,0.00010190915,0.0001640912,0.0010623366,0.00021694794,0.00003546053,0.0004947252,0.0005002832],"genre_scores_gemma":[0.99800444,0.0004919298,0.00010638969,0.00044910464,0.000060373364,0.000014657896,0.00015681052,0.000067861394,0.0006484419],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981281,0.00064829434,0.00031728932,0.00045206698,0.000051087394,0.00040314623],"domain_scores_gemma":[0.9992432,0.000085082705,0.00006703085,0.0005131651,0.000052670235,0.000038876868],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037439496,0.00031818703,0.00033762836,0.00014833357,0.00027135533,0.00013768594,0.00031004119,0.00033193908,0.0009940511],"category_scores_gemma":[0.00006543731,0.0002729963,0.00014055487,0.0001742264,0.00014025674,0.00023404673,0.00011050226,0.000513872,0.00011792423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073812186,0.00011055153,0.00007770572,0.000018087925,0.00039369625,0.00003381579,0.00072507793,2.1929347e-7,0.9772774,0.00033082347,0.0013261536,0.018968333],"study_design_scores_gemma":[0.0010995524,0.0008382723,0.004458944,0.00005897597,0.000020504114,0.00006200566,0.00020270165,0.000026259797,0.89243484,0.000049923998,0.10046104,0.00028701217],"about_ca_topic_score_codex":0.000113682516,"about_ca_topic_score_gemma":0.0000013070954,"teacher_disagreement_score":0.09913489,"about_ca_system_score_codex":0.000038392835,"about_ca_system_score_gemma":0.00005582719,"threshold_uncertainty_score":0.9999722},"labels":[],"label_agreement":null},{"id":"W4405311484","doi":"10.1016/j.omtn.2024.102423","title":"Restoring hematopoietic stem and progenitor cell function in Fancc mice by in situ delivery of RNA lipid nanoparticles","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"Office of Extramural Research, National Institutes of Health; Children's Hospital of Philadelphia","keywords":"Haematopoiesis; Progenitor cell; Ex vivo; Stem cell; Bone marrow; Gene delivery; Genetic enhancement; Biology; Hematopoietic stem cell; Cell biology; Cancer research; In vivo; Immunology; Gene; Genetics","score_opus":0.00806716529950856,"score_gpt":0.21857951823474375,"score_spread":0.21051235293523518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405311484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97581863,0.023382012,0.00020028367,0.000055508026,0.0001886181,0.00019469483,0.0000047328913,0.000015223598,0.00014030664],"genre_scores_gemma":[0.99806553,0.0014801201,0.00007863936,0.00011245939,0.000047897724,0.000029114843,0.000013631241,0.00003325044,0.00013937964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889976,0.00007893315,0.00027670557,0.00038552887,0.0001319686,0.00022710167],"domain_scores_gemma":[0.999646,0.000009820075,0.000043275282,0.00021841763,0.000033698052,0.000048802707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016551331,0.00017284145,0.00017311817,0.000097619566,0.000021575803,0.000035391204,0.00013392112,0.000146911,0.0000064348555],"category_scores_gemma":[0.000003998289,0.00016988152,0.000070689435,0.00017224773,0.00005436291,0.000013835114,0.000061072344,0.0001130452,0.000007594806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002046786,0.000081506565,0.001612434,0.00007165398,0.000034454486,0.000023257466,0.0002880591,0.00002032592,0.9875289,0.000014593658,0.00016879331,0.009951339],"study_design_scores_gemma":[0.00054196717,0.0004604291,0.00064088823,0.00009084737,0.000010472551,0.000007843743,0.0002433927,0.00007857009,0.995052,0.000039311828,0.002655394,0.0001789134],"about_ca_topic_score_codex":0.000037061007,"about_ca_topic_score_gemma":0.000020591333,"teacher_disagreement_score":0.022246888,"about_ca_system_score_codex":0.000022988725,"about_ca_system_score_gemma":0.00004054965,"threshold_uncertainty_score":0.6927568},"labels":[],"label_agreement":null},{"id":"W4405311671","doi":"10.1016/j.omtn.2024.102426","title":"Flow rate modulates focused ultrasound-mediated vascular delivery of microRNA","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Canadian Institutes of Health Research; Fonds de recherche du Québec; Canadian Cardiovascular Society; Canada Research Chairs; Burroughs Wellcome Fund","keywords":"Ultrasound; Gene delivery; Medicine; Contrast-enhanced ultrasound; Vasoconstriction; Vasodilation; Genetic enhancement; Cardiology; Biomedical engineering; Radiology; Internal medicine; Gene; Biology","score_opus":0.005854648818821226,"score_gpt":0.19115408031463937,"score_spread":0.18529943149581815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405311671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96482044,0.01357825,0.019565836,0.00008485427,0.00020841736,0.00029081266,0.000065369066,0.00071651716,0.0006695266],"genre_scores_gemma":[0.9941923,0.002769072,0.0024736975,0.00016197797,0.000063895,0.00005138562,0.000097617754,0.00014691883,0.00004310938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988215,0.000050826282,0.00031070085,0.00030697157,0.00018986888,0.00032015372],"domain_scores_gemma":[0.99920696,0.00012709074,0.000024194442,0.00048850046,0.000058382957,0.00009484341],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015402399,0.00028868983,0.00028496943,0.00014853234,0.000061268685,0.00008876829,0.00029847494,0.00016381971,0.00026645552],"category_scores_gemma":[0.000011975537,0.00027080352,0.00027057418,0.00048550445,0.00008590229,0.0001173954,0.000015981872,0.00021632429,0.00024018377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008827098,0.00003970084,0.000057214376,0.000050205785,0.00047274673,0.00001600636,0.00047011618,0.004996803,0.97876215,0.0002604156,0.00023409213,0.014631736],"study_design_scores_gemma":[0.0011831864,0.000107164145,0.0012780552,0.00013194841,0.00012259929,0.000026706253,0.00010053289,0.08359226,0.81736374,0.0012656343,0.094025426,0.00080275786],"about_ca_topic_score_codex":0.000028193257,"about_ca_topic_score_gemma":0.000002822345,"teacher_disagreement_score":0.16139841,"about_ca_system_score_codex":0.00006655841,"about_ca_system_score_gemma":0.000031876585,"threshold_uncertainty_score":0.9999744},"labels":[],"label_agreement":null},{"id":"W4405663975","doi":"10.1016/j.omtn.2024.102442","title":"Glutamine missense suppressor transfer RNAs inhibit polyglutamine aggregation","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bioinformatics Solutions (Canada); Western University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Western University; Schulich School of Medicine and Dentistry; Huntington Society of Canada","keywords":"Missense mutation; Suppressor; Glutamine; Chemistry; Cell biology; Biology; Mutation; Biochemistry; Amino acid; Gene","score_opus":0.009964462752732703,"score_gpt":0.2568469801517559,"score_spread":0.24688251739902317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405663975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9708003,0.011492572,0.015256766,0.0010952001,0.00017136308,0.00035958082,0.000032318894,0.00009284239,0.00069909275],"genre_scores_gemma":[0.99321234,0.0011557097,0.0003944425,0.00072358345,0.00025902485,0.000038836,0.00019653376,0.00011146428,0.003908059],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980796,0.000121786776,0.00028506602,0.0006199567,0.0003683209,0.0005252574],"domain_scores_gemma":[0.99914646,0.000016184898,0.000019431522,0.0005366718,0.00008235354,0.00019887142],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025970108,0.00031048313,0.00021192501,0.0001394357,0.00011001526,0.00015702279,0.00028321162,0.0002391534,0.00018714144],"category_scores_gemma":[0.000043401993,0.0002763982,0.00025159563,0.00028054285,0.00012323546,0.000014688951,0.00006159233,0.0002348537,0.000091297574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023653216,0.00006668015,0.000050307943,0.000035358345,0.00017434414,0.0002630798,0.00009333536,0.000032944896,0.9578181,0.00027956077,0.0007446457,0.040205147],"study_design_scores_gemma":[0.0009105393,0.0005375806,0.00020389036,0.000056374072,0.000016594282,0.0001150451,0.000033866956,0.0008686976,0.9166121,0.00009671763,0.080231056,0.00031755175],"about_ca_topic_score_codex":0.000036243317,"about_ca_topic_score_gemma":0.000008361909,"teacher_disagreement_score":0.07948641,"about_ca_system_score_codex":0.000030614305,"about_ca_system_score_gemma":0.00008770527,"threshold_uncertainty_score":0.9999688},"labels":[],"label_agreement":null},{"id":"W4405664011","doi":"10.1016/j.omtn.2024.102443","title":"Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells","year":2024,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; Women and Children’s Health Research Institute; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Canadian Institutes of Health Research; Alberta Innovates; Sorbonne Université; Institut National de la Santé et de la Recherche Médicale; Canada Foundation for Innovation; Washington University in St. Louis; University of Alberta; Institut de Myologie; Ministry of Advanced Education, Government of Alberta; Women and Children's Health Research Institute; Children's Health Research Institute; Muscular Dystrophy Canada","keywords":"Dysferlin; Exon; Oligonucleotide; Exon skipping; Function (biology); Cell biology; Biology; Molecular biology; Chemistry; Gene; Genetics; Alternative splicing","score_opus":0.006785285477674614,"score_gpt":0.21786673153016983,"score_spread":0.2110814460524952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405664011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898252,0.0065047443,0.0014340294,0.00021614989,0.00093766325,0.0004356425,0.000023401142,0.00012419958,0.00049900566],"genre_scores_gemma":[0.99624056,0.0015871397,0.00019245099,0.0013848612,0.00012714512,0.000044241748,0.00027047298,0.000107017026,0.000046131026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99768895,0.00027984657,0.00042782395,0.0008448293,0.00021387667,0.00054465357],"domain_scores_gemma":[0.9991173,0.000031403135,0.00007457508,0.00058352173,0.00006345046,0.00012974211],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021192933,0.0003949991,0.0002958752,0.00020785419,0.00010994186,0.000070718146,0.0002470578,0.0003919504,0.00011502002],"category_scores_gemma":[0.000049100006,0.0003935264,0.00022306162,0.00036120042,0.00016550605,0.000021401791,0.00011061194,0.00031044375,0.00013276712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005261832,0.00015499617,0.00029155918,0.00003484961,0.000104081264,0.000119255,0.00029355098,0.00032276468,0.9795201,0.000106627296,0.0005756543,0.017950397],"study_design_scores_gemma":[0.0019279737,0.0016403807,0.01184093,0.00010724457,0.00003323934,0.000010818013,0.00037242004,0.0007933648,0.94097054,0.0005386149,0.040945835,0.0008186094],"about_ca_topic_score_codex":0.00005148442,"about_ca_topic_score_gemma":0.000034382898,"teacher_disagreement_score":0.04037018,"about_ca_system_score_codex":0.00003650288,"about_ca_system_score_gemma":0.000093662304,"threshold_uncertainty_score":0.99985164},"labels":[],"label_agreement":null},{"id":"W4406559961","doi":"10.1016/j.omtn.2025.102457","title":"Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group","year":2025,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Instituto de Salud Carlos III; Junta de Andalucía; Novo Nordisk Fonden; Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja; European Research Council; Ministerio de Ciencia, Innovación y Universidades; Alexion Pharmaceuticals; Javna Agencija za Raziskovalno Dejavnost RS; Centre National de la Recherche Scientifique; Ministerio de Ciencia e Innovación; Novo Nordisk; H. Lundbeck A/S; Ikerbasque, Basque Foundation for Science; Lundbeckfonden; European Cooperation in Science and Technology; Innovationsfonden; Consejería de Salud y Consumo, Junta de Andalucía; Eusko Jaurlaritza","keywords":"Genome editing; Computational biology; Computer science; Gene delivery; Genome; Genetic enhancement; Biology; Action (physics); Gene; Genetics","score_opus":0.035202050850889934,"score_gpt":0.3437855952266771,"score_spread":0.30858354437578717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406559961","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027711652,0.953536,0.04072954,0.000047356003,0.0014069588,0.0036833573,0.00022664662,0.000050764404,0.000042298157],"genre_scores_gemma":[0.00018434804,0.9921805,0.0011924081,0.0009796929,0.0010886608,0.0013531181,0.0027680006,0.00015962654,0.000093609204],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99731696,0.00028787376,0.000726434,0.00091978523,0.00025647398,0.00049246807],"domain_scores_gemma":[0.9980706,0.00014346252,0.0003881923,0.0011428202,0.00015485415,0.000100097444],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025064638,0.0007353673,0.0012986144,0.000067902525,0.00021630764,0.0000947067,0.00075504807,0.00043394856,0.000009419012],"category_scores_gemma":[0.00006877185,0.0005838086,0.0009783437,0.00026616972,0.0000639856,0.0000049863547,0.0001928015,0.00034007442,0.000008039129],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043816322,0.0000361386,0.0000014725324,0.008171296,0.00092217437,0.000012321264,0.000012627813,0.0001956059,0.023892308,0.000011620481,0.0022234945,0.9644771],"study_design_scores_gemma":[0.0005838367,0.00012041448,0.0000023010873,0.013919512,0.00061213033,0.000032745498,0.00002751217,0.000040279785,0.0035341405,0.0000054793963,0.9805755,0.00054615736],"about_ca_topic_score_codex":0.000022290273,"about_ca_topic_score_gemma":0.0000034873453,"teacher_disagreement_score":0.978352,"about_ca_system_score_codex":0.00007867556,"about_ca_system_score_gemma":0.00013587362,"threshold_uncertainty_score":0.9996613},"labels":[],"label_agreement":null},{"id":"W4406559981","doi":"10.1016/j.omtn.2025.102452","title":"Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"All-India Institute of Medical Sciences; Science and Engineering Research Board; Indian Council of Medical Research; Department of Science and Technology, Ministry of Science and Technology, India; Biotechnology Industry Research Assistance Council; Department of Biotechnology, Ministry of Science and Technology, India","keywords":"Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Virology; Betacoronavirus; Neuroscience; Biology; Cognitive science; Psychology; Medicine; Internal medicine; Infectious disease (medical specialty)","score_opus":0.02719437708116154,"score_gpt":0.3292249288919773,"score_spread":0.30203055181081573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406559981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98892266,0.004904146,0.0006615551,0.0016503265,0.000047194466,0.0004743245,0.000004085949,0.000069139656,0.003266572],"genre_scores_gemma":[0.983048,0.00011861604,0.00015189187,0.016525732,0.000019151244,0.00003394902,0.000004370071,0.00003536021,0.000062910796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985109,0.000134929,0.00021662396,0.00048607914,0.00030494292,0.0003465012],"domain_scores_gemma":[0.9994806,0.00005781885,0.00005122674,0.00031554597,0.00006381534,0.00003098407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039366237,0.00022016469,0.00034368766,0.00027233537,0.00010013261,0.00006116187,0.00010916545,0.00020519995,0.000005526333],"category_scores_gemma":[0.00008978019,0.00021047657,0.000060756192,0.00047875853,0.000106169886,0.00011987244,0.00008565695,0.00033313542,0.000009396526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060452934,0.0001014024,0.016361088,0.00006233139,0.0000690318,0.00004903287,0.000261113,2.0741244e-7,0.9421042,0.00050271215,0.00020036487,0.039683945],"study_design_scores_gemma":[0.003334431,0.00022585237,0.031160658,0.00013199287,0.000020906158,0.000015891184,0.000039111546,0.0013712171,0.9324419,0.00081426825,0.030257601,0.00018615973],"about_ca_topic_score_codex":0.00011931947,"about_ca_topic_score_gemma":0.000014446647,"teacher_disagreement_score":0.039497785,"about_ca_system_score_codex":0.00009951084,"about_ca_system_score_gemma":0.00009786585,"threshold_uncertainty_score":0.85829854},"labels":[],"label_agreement":null},{"id":"W4407058584","doi":"10.1016/j.omtn.2025.102472","title":"Enhanced HDR-mediated correction of heterozygous COL7A1 mutations for recessive dystrophic epidermolysis bullosa","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Directorate for Biological Sciences; University of Auckland; Maurice Wilkins Centre for Molecular Biodiscovery; Auckland Medical Research Foundation","keywords":"Epidermolysis bullosa dystrophica; Genetics; Mutation; Epidermolysis bullosa; Compound heterozygosity; Dermatology; Biology; Medicine; Gene","score_opus":0.008778180880717886,"score_gpt":0.27844631168796496,"score_spread":0.26966813080724705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407058584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9191131,0.0019042162,0.07698458,0.00024726428,0.0003795336,0.0007149263,0.000039892497,0.000026192085,0.000590301],"genre_scores_gemma":[0.9964843,0.00056740583,0.0006190172,0.00026185196,0.000056006196,0.00027955233,0.0006762167,0.00003604965,0.0010195981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984508,0.00021646344,0.00035445066,0.0004916778,0.00014651373,0.00034006016],"domain_scores_gemma":[0.99890214,0.00007218103,0.00014897126,0.00048334358,0.00032365028,0.000069725225],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024090093,0.00022275266,0.00030274442,0.00015726713,0.00014942672,0.000020916772,0.00030746692,0.00033176132,0.00004625518],"category_scores_gemma":[0.0002854345,0.0002151192,0.000269374,0.00035415852,0.0002393108,0.0000042664983,0.00006994701,0.00013550403,0.000009162027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005630284,0.00013601368,0.00011899341,0.00002243121,0.00039572708,0.000019388495,0.00005374459,0.00009303813,0.98224735,0.000053585507,0.00038451765,0.015912183],"study_design_scores_gemma":[0.0017320447,0.00069245684,0.00022628582,0.000026078667,0.00003978066,0.0000304103,0.00010324678,0.00046726826,0.9913088,0.0003776369,0.0047989963,0.0001969738],"about_ca_topic_score_codex":0.000021379592,"about_ca_topic_score_gemma":0.000005601423,"teacher_disagreement_score":0.0773712,"about_ca_system_score_codex":0.000028856593,"about_ca_system_score_gemma":0.0001374336,"threshold_uncertainty_score":0.87723064},"labels":[],"label_agreement":null},{"id":"W4407811579","doi":"10.1016/j.omtn.2025.102481","title":"Unlocking RNA mysteries: Predicting subcellular localizations with AI","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Science and Technology Council","keywords":"Subcellular localization; Computational biology; RNA; Computer science; Artificial intelligence; Biology; Chemistry; Biochemistry; Gene","score_opus":0.006064512802385335,"score_gpt":0.2278685651517157,"score_spread":0.22180405234933034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407811579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5507594,0.0019822984,0.44369712,0.00043664477,0.00012908477,0.0003632484,0.000006688126,0.000061594656,0.0025639245],"genre_scores_gemma":[0.99376124,0.00020577582,0.002242797,0.0025432338,0.000076626486,0.00008020659,0.00006330125,0.00006603082,0.0009608103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854106,0.00013944435,0.00026185552,0.0004977892,0.00021127626,0.00034859],"domain_scores_gemma":[0.9990403,0.000010650979,0.00008877836,0.0006595994,0.0001235733,0.00007707887],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020563873,0.00027924927,0.00021831531,0.00009142606,0.00024092951,0.00009363321,0.00035024717,0.00021796534,0.00006104784],"category_scores_gemma":[0.00003704382,0.00024627635,0.00012008992,0.0002902125,0.00010615887,0.000008934478,0.000094694835,0.000116726515,0.000010414146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001808962,0.000052047824,0.0014665324,0.000022640925,0.00021595758,0.000020488198,0.00008802703,0.0003307063,0.9879209,0.0014371878,0.00013573554,0.008128897],"study_design_scores_gemma":[0.00079702056,0.00034270535,0.000106811705,0.00008947511,0.000031987565,0.000011499811,0.00011997723,0.00025635358,0.9398347,0.0005078176,0.057617906,0.00028370842],"about_ca_topic_score_codex":0.000017031718,"about_ca_topic_score_gemma":0.0000055172413,"teacher_disagreement_score":0.44300184,"about_ca_system_score_codex":0.000021860498,"about_ca_system_score_gemma":0.0001138452,"threshold_uncertainty_score":0.9999989},"labels":[],"label_agreement":null},{"id":"W4407852498","doi":"10.1016/j.omtn.2025.102496","title":"CAG-targeted brain-permeable therapy tested in biallelic humanized polyQ mouse models","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Narodowe Centrum Badań i Rozwoju; Ministerstwo Edukacji i Nauki; Polska Akademia Nauk; Agence Nationale de la Recherche; National Ataxia Foundation","keywords":"Biology; Computational biology","score_opus":0.030751875866741052,"score_gpt":0.27358322947710845,"score_spread":0.2428313536103674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407852498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99125594,0.0017157578,0.0016864662,0.0018427836,0.00023547719,0.0012732963,0.000032101718,0.00031223748,0.0016459516],"genre_scores_gemma":[0.97392225,0.0007047357,0.0003351998,0.021934124,0.000031542826,0.00018891178,0.000015440528,0.00012888234,0.0027389165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959438,0.0008846206,0.0005677443,0.001230882,0.00056193187,0.0008110156],"domain_scores_gemma":[0.9982424,0.00019706065,0.00013166206,0.001144738,0.00011177064,0.00017237262],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022989654,0.0005732594,0.0005298153,0.0005311715,0.00028347792,0.00019287114,0.0010145117,0.00014740795,0.0002693537],"category_scores_gemma":[0.00026808179,0.00054427003,0.0002521944,0.0013852137,0.00024043853,0.00021663625,0.0001465496,0.00034485557,0.00006466335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033241487,0.0005285387,0.00035933746,0.000009178931,0.000031580825,0.000083879786,0.000496871,0.004273232,0.9882093,0.0022682133,0.00068684015,0.0027206333],"study_design_scores_gemma":[0.0046662497,0.00017297418,0.0014241264,0.000024235018,0.000007583664,0.0000038904345,0.000047404363,0.0075233863,0.979623,0.003574427,0.0024387669,0.000493948],"about_ca_topic_score_codex":0.00015484539,"about_ca_topic_score_gemma":0.000029199911,"teacher_disagreement_score":0.020091342,"about_ca_system_score_codex":0.00010630253,"about_ca_system_score_gemma":0.00023655551,"threshold_uncertainty_score":0.9997009},"labels":[],"label_agreement":null},{"id":"W4408159908","doi":"10.1016/j.omtn.2025.102500","title":"High-throughput 3D spheroid screens identify microRNA sensitizers for improved thermoradiotherapy in locally advanced cancers","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Cancer Center Amsterdam; China Scholarship Council","keywords":"microRNA; Biomarker; Oncology; Medicine; Head and neck cancer; Radiation therapy; Cancer research; Chemoradiotherapy; DNA repair; Cervical cancer; DNA damage; Chemotherapy; Cancer; Internal medicine; Biology; DNA; Gene","score_opus":0.00530990667543124,"score_gpt":0.2601103523439359,"score_spread":0.2548004456685047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408159908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90002286,0.0052629453,0.092020825,0.00067019137,0.00032939276,0.0014202833,0.000068027235,0.000052584557,0.00015286184],"genre_scores_gemma":[0.97643,0.0009383171,0.0175298,0.003991539,0.00012380086,0.00017662054,0.00030795592,0.00013116814,0.0003708007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978477,0.0001405766,0.00046130025,0.00084188767,0.00014828077,0.0005602766],"domain_scores_gemma":[0.99871606,0.000018832669,0.00016805489,0.00082599133,0.00017140195,0.00009966882],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024741725,0.00042376036,0.00040407525,0.00012540651,0.00011673727,0.000051989882,0.0004047926,0.0003343723,0.000041391762],"category_scores_gemma":[0.000036917267,0.00044957487,0.0002804154,0.00032765296,0.00017625093,0.000014834459,0.000072818555,0.0001468744,0.0000049218716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015613603,0.00008072722,0.00018136427,0.00003098563,0.00030588935,0.0000094907355,0.000051036946,0.0018476552,0.9623252,0.00013024163,0.00048548775,0.03299055],"study_design_scores_gemma":[0.0076056155,0.0003623224,0.003845656,0.0000841209,0.000036368496,0.000006059483,0.00007818288,0.0011360962,0.9595729,0.0005448217,0.026151102,0.0005767412],"about_ca_topic_score_codex":0.00015015155,"about_ca_topic_score_gemma":0.00011706734,"teacher_disagreement_score":0.07640711,"about_ca_system_score_codex":0.00024620205,"about_ca_system_score_gemma":0.00032633595,"threshold_uncertainty_score":0.9997956},"labels":[],"label_agreement":null},{"id":"W4408251708","doi":"10.1016/j.omtn.2025.102507","title":"microRNA-133a as an indicator of disease progression and treatment response in X-linked myotubular myopathy","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Canadian Institutes of Health Research; National Institutes of Health; Myotubular Trust","keywords":"microRNA; Myopathy; Disease; Medicine; Biology; Genetics; Pathology; Gene","score_opus":0.00614027952128546,"score_gpt":0.27597877274607313,"score_spread":0.26983849322478765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408251708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935015,0.005373769,0.00014000606,0.00038283507,0.000044312208,0.00043362952,0.000012823972,0.000014310433,0.0000968305],"genre_scores_gemma":[0.9977472,0.0009795859,0.00024948575,0.0007680016,0.000014466605,0.000072540264,0.000086089414,0.000023794215,0.000058843518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986338,0.0003465077,0.00022920681,0.00047693044,0.000088099376,0.00022547066],"domain_scores_gemma":[0.9992494,0.000013462043,0.000078522564,0.0005099978,0.000029246643,0.000119381984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002000544,0.00021696383,0.00022054535,0.00013033216,0.00006539255,0.0000123754335,0.00018564545,0.00019124085,0.00001955228],"category_scores_gemma":[0.00004464989,0.00019023735,0.0000963942,0.00013114711,0.00020702489,0.000006113089,0.0000714555,0.00007448005,0.0000029492192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0148379225,0.0005456096,0.012057309,0.00001426952,0.000082301194,0.000022844113,0.00017147894,0.0000140756265,0.9554794,0.00018577832,0.000017017162,0.016572038],"study_design_scores_gemma":[0.0060158633,0.0047083003,0.2505151,0.000068294255,0.00004150079,0.000002795141,0.00016494453,0.000066722045,0.7260528,0.0016182413,0.010358985,0.0003864167],"about_ca_topic_score_codex":0.000018747298,"about_ca_topic_score_gemma":0.0000043289187,"teacher_disagreement_score":0.2384578,"about_ca_system_score_codex":0.000019105344,"about_ca_system_score_gemma":0.00017028164,"threshold_uncertainty_score":0.77576536},"labels":[],"label_agreement":null},{"id":"W4409592270","doi":"10.1016/j.omtn.2025.102538","title":"CyKILR splice variants: A double-edged sword in non-small cell lung cancer","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"","keywords":"SWORD; splice; Lung cancer; Biology; Medicine; Computational biology; Genetics; Internal medicine; Computer science; Gene; World Wide Web","score_opus":0.007648227298921878,"score_gpt":0.27807642708089614,"score_spread":0.27042819978197424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409592270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86465144,0.016620992,0.105330236,0.0008498426,0.00056933553,0.0017970327,0.000027319787,0.000064233645,0.010089589],"genre_scores_gemma":[0.9877219,0.004244573,0.0012739897,0.0031972162,0.00013617145,0.0005657842,0.0000924147,0.00015340695,0.0026145393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969629,0.00019745778,0.00048241098,0.0010975923,0.00036344735,0.0008961907],"domain_scores_gemma":[0.998296,0.00001474354,0.00011820821,0.0011932685,0.00019712317,0.00018065318],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043893926,0.00049774855,0.0004209692,0.00034691553,0.00014530032,0.00008355741,0.000900718,0.0005894543,0.00018707625],"category_scores_gemma":[0.00002632363,0.0005321612,0.00028191702,0.0009214923,0.00010500712,0.0000105574,0.00037385718,0.00057075534,0.0000275547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00097491115,0.00024743768,0.0004001226,0.00008056881,0.0002624437,0.00009617335,0.00014336493,0.0012078844,0.9890742,0.000185131,0.001427889,0.0058998996],"study_design_scores_gemma":[0.0078215245,0.00025686633,0.000945494,0.00014576748,0.000050619663,0.000008663274,0.00008633276,0.0017365629,0.9618699,0.00014101171,0.026324388,0.0006128651],"about_ca_topic_score_codex":0.00043624282,"about_ca_topic_score_gemma":0.00019031213,"teacher_disagreement_score":0.123070486,"about_ca_system_score_codex":0.00019962715,"about_ca_system_score_gemma":0.0005287723,"threshold_uncertainty_score":0.999713},"labels":[],"label_agreement":null},{"id":"W4410487724","doi":"10.1016/j.omtn.2025.102571","title":"A novel miniaturized filamentous phagemid as a gene delivery vehicle to target mammalian cells","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Consejo Nacional de Ciencia y Tecnología","keywords":"Phagemid; Gene delivery; Transgene; Biology; DNA; Plasmid; Phage display; Gene; In vitro recombination; Molecular biology; Computational biology; Cell biology; Genetic enhancement; Bacteriophage; Gene expression; Genetics; Molecular cloning; Escherichia coli","score_opus":0.0068319162068135155,"score_gpt":0.2389225969171793,"score_spread":0.2320906807103658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410487724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98698837,0.0021778825,0.0071435883,0.0004946629,0.0003722287,0.00057176896,0.000055596352,0.000045723133,0.0021501547],"genre_scores_gemma":[0.9697678,0.00034573916,0.009184139,0.014403346,0.00012435172,0.000106261614,0.00012146685,0.00006398639,0.0058829053],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99806255,0.00008008154,0.0003403554,0.0007522481,0.00023544897,0.0005292903],"domain_scores_gemma":[0.9987693,0.000009442908,0.00007926301,0.00081149506,0.00015000066,0.00018053663],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016142406,0.00037939716,0.00030247006,0.0001496845,0.0001262551,0.000096078074,0.00063849473,0.0002788562,0.00019839006],"category_scores_gemma":[0.000026915186,0.00038254104,0.00027967145,0.0002939348,0.000071406,0.000008698881,0.00024667004,0.00015367773,0.00023237172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007295806,0.00021514019,0.00005052963,0.000010619047,0.00025322833,0.00007732327,0.000110613,0.00010443418,0.9888341,0.000037712594,0.0044681136,0.0051086363],"study_design_scores_gemma":[0.0016900147,0.0006262915,0.00040560824,0.000023642597,0.000023545801,0.00001827626,0.00006004896,0.00004857931,0.87469214,0.00008799017,0.121961966,0.0003618687],"about_ca_topic_score_codex":0.0000902637,"about_ca_topic_score_gemma":0.000007631372,"teacher_disagreement_score":0.11749385,"about_ca_system_score_codex":0.000041976793,"about_ca_system_score_gemma":0.00014207995,"threshold_uncertainty_score":0.9998627},"labels":[],"label_agreement":null},{"id":"W4410701408","doi":"10.1016/j.omtn.2025.102579","title":"Albumin-binding dendritic siRNA improves delivery and efficacy to solid tumors in a melanoma model","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; NIH Office of the Director","keywords":"Melanoma; Cancer research; Albumin; Medicine; Chemistry; Internal medicine","score_opus":0.008388585576780957,"score_gpt":0.25772908766826,"score_spread":0.24934050209147907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410701408","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935042,0.0017103533,0.0032828825,0.00028773336,0.00010331459,0.0003694509,0.000009251468,0.000020487192,0.0007123046],"genre_scores_gemma":[0.99505174,0.00041314596,0.0008747196,0.002844686,0.000033780732,0.00004720881,0.00002608755,0.000037655274,0.0006709694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99849325,0.00006208014,0.0003122935,0.0005898675,0.00012684353,0.0004156376],"domain_scores_gemma":[0.99933016,0.000011879885,0.000047400274,0.00043320376,0.00006476217,0.000112582486],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014611178,0.0002803939,0.00027883545,0.00021606198,0.000083317056,0.00006959679,0.00033755004,0.00018442936,0.000007792764],"category_scores_gemma":[0.000044279135,0.00028517353,0.000116763185,0.00020809565,0.00007556351,0.000009744818,0.00020590932,0.00014477473,0.000016363152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026393266,0.00008839652,0.00073000067,0.0000133807425,0.0000871842,0.000036661448,0.00016547719,0.00040043675,0.98429537,0.000104877494,0.00022731362,0.01358698],"study_design_scores_gemma":[0.0017744378,0.0006314425,0.0032778296,0.00011614382,0.000021060117,0.000017100609,0.00018039113,0.0030290904,0.9888708,0.00028242267,0.001348747,0.00045055614],"about_ca_topic_score_codex":0.00003774444,"about_ca_topic_score_gemma":0.000025936562,"teacher_disagreement_score":0.013136424,"about_ca_system_score_codex":0.000032986427,"about_ca_system_score_gemma":0.000097705575,"threshold_uncertainty_score":0.99996006},"labels":[],"label_agreement":null},{"id":"W4410740430","doi":"10.1016/j.omtn.2025.102575","title":"Advantages, applications, and future directions of in vivo aptamer SELEX: A review","year":2025,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Research Grants Council, University Grants Committee; University Grants Committee","keywords":"Aptamer; Systematic evolution of ligands by exponential enrichment; Computational biology; Nanotechnology; Computer science; Biochemical engineering; Biology; Engineering; Materials science; Genetics; RNA","score_opus":0.00795773366503289,"score_gpt":0.31026959094684103,"score_spread":0.30231185728180815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410740430","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000026211714,0.99761647,0.000571149,0.000092593276,0.000032473265,0.0011127234,0.000090357236,0.000035045512,0.00042295616],"genre_scores_gemma":[0.00002495967,0.99564934,0.0029080736,0.0004415579,0.00010484947,0.000266689,0.00024966444,0.000049617673,0.00030527482],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99818575,0.00022119432,0.0005953599,0.00064246904,0.00013946636,0.00021572816],"domain_scores_gemma":[0.99874884,0.000017660017,0.00031694095,0.0007695458,0.000091840506,0.000055201916],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022211576,0.00043192474,0.0011986003,0.00021226297,0.00005398262,0.0000126784025,0.0002785571,0.00043393477,0.000007477114],"category_scores_gemma":[0.000022056787,0.00035495692,0.0004726564,0.0007510509,0.00012431708,0.0000035856594,0.000113031376,0.00023806238,9.586099e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008067002,0.00007424409,0.00000440611,0.0063921204,0.00020269916,0.0000036305562,0.0000027924675,2.9804948e-8,0.0047383183,0.000055549346,0.00035917305,0.98815894],"study_design_scores_gemma":[0.00013418413,0.00007484168,0.0000014670001,0.006908042,0.00030390645,0.000022739832,0.000006520492,2.6973638e-7,0.00464984,0.000029165718,0.98754555,0.00032346384],"about_ca_topic_score_codex":0.0000062818594,"about_ca_topic_score_gemma":0.0000050013155,"teacher_disagreement_score":0.9878355,"about_ca_system_score_codex":0.00002725302,"about_ca_system_score_gemma":0.000119053555,"threshold_uncertainty_score":0.99989027},"labels":[],"label_agreement":null},{"id":"W4411343261","doi":"10.1016/j.omtn.2025.102611","title":"RNA activation of CEBPA improves leukemia treatment","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Cole Foundation; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs","keywords":"CEBPA; Leukemia; RNA; Cancer research; Computational biology; Medicine; Biology; Internal medicine; Genetics; Mutation; Gene","score_opus":0.013975447590367623,"score_gpt":0.2951084991821662,"score_spread":0.2811330515917986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411343261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9816118,0.0006724517,0.0032260886,0.0019890657,0.00007623816,0.00081582763,0.0000045188394,0.000082617895,0.011521375],"genre_scores_gemma":[0.9927085,0.0005647555,0.0016931585,0.0012983553,0.000050070445,0.0000689821,0.00003598486,0.000045983325,0.003534183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858797,0.0000853515,0.0003155221,0.00035567395,0.00032526767,0.00033024227],"domain_scores_gemma":[0.9989019,0.00005639618,0.00008749902,0.0006937846,0.00016050755,0.00009989846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015740962,0.00023840794,0.0004189533,0.00028635346,0.00006985964,0.000018679782,0.0001912904,0.00018364514,0.00014538884],"category_scores_gemma":[0.000062189196,0.00019011312,0.00021788872,0.000507002,0.00014452594,0.00007064686,0.000053888376,0.00021201205,0.000029400722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073194405,0.00016163975,0.0007311755,0.0000390447,0.00042535155,0.0000313284,0.00020847282,0.000010467429,0.85238034,0.00089493877,0.00037572626,0.1440096],"study_design_scores_gemma":[0.0050328877,0.0010129538,0.0094549665,0.000079270154,0.000060519676,0.0000074404666,0.0001151164,0.0005633495,0.9616634,0.0004611465,0.021414533,0.00013441232],"about_ca_topic_score_codex":0.00020617514,"about_ca_topic_score_gemma":0.0000012034221,"teacher_disagreement_score":0.14387518,"about_ca_system_score_codex":0.0011325093,"about_ca_system_score_gemma":0.0007210937,"threshold_uncertainty_score":0.77525884},"labels":[],"label_agreement":null},{"id":"W4412736158","doi":"10.1016/j.omtn.2025.102645","title":"mRNA-LNP vaccine encoding the Plasmodium vivax circumsporozoite protein is highly immunogenic and confers protection in mice","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Faculty of Tropical Medicine, Mahidol University; National Institutes of Health; Walter Reed Army Institute of Research; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Circumsporozoite protein; Virology; Malaria vaccine; Plasmodium vivax; Immunogenicity; Biology; Malaria; Plasmodium falciparum; Immune system; Immunology","score_opus":0.015190294706302168,"score_gpt":0.2744072053278249,"score_spread":0.25921691062152274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412736158","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97649515,0.002303002,0.001400649,0.01743047,0.00008459513,0.0017175106,0.0000054417046,0.000052711628,0.00051046],"genre_scores_gemma":[0.994136,0.0008746652,0.00027400238,0.0039580143,0.000043599288,0.00023960895,0.000010823926,0.000030509153,0.0004328271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981205,0.00030969808,0.0004036869,0.00043064242,0.00021192417,0.000523576],"domain_scores_gemma":[0.9993367,0.000017646295,0.00008173453,0.00038427793,0.00007984678,0.000099790224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006187746,0.00023422195,0.00041651024,0.00023612536,0.00013982806,0.0000436522,0.00021371806,0.00015927474,0.000082561244],"category_scores_gemma":[0.00013805344,0.00017571443,0.00012663084,0.00036671743,0.00012688986,0.00008121801,0.000092022805,0.0005414632,0.00001579072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016290154,0.000079662845,0.0050729783,0.0000628781,0.00017403574,0.000091633054,0.00020806876,0.0000038100402,0.9740314,0.000264155,0.00021312866,0.018169275],"study_design_scores_gemma":[0.020719305,0.003920041,0.19100216,0.001189577,0.0000932727,0.0004242319,0.00069598894,0.0023352816,0.7302821,0.0033439188,0.04536033,0.0006337595],"about_ca_topic_score_codex":0.00041283097,"about_ca_topic_score_gemma":0.000019024095,"teacher_disagreement_score":0.24374922,"about_ca_system_score_codex":0.00013149584,"about_ca_system_score_gemma":0.000088331384,"threshold_uncertainty_score":0.71654266},"labels":[],"label_agreement":null},{"id":"W4413051598","doi":"10.1016/j.omtn.2025.102636","title":"Off-target effects in CRISPR-Cas genome editing for human therapeutics: Progress and challenges","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"HORIZON EUROPE Framework Programme; Consejería de Salud y Consumo, Junta de Andalucía; Junta de Andalucía; Novo Nordisk Fonden; Danmarks Frie Forskningsfond; Novo Nordisk; Deutsche Forschungsgemeinschaft; European Cooperation in Science and Technology; HORIZON EUROPE European Institute of Innovation and Technology; European Commission; Fundación Mutua Madrileña","keywords":"CRISPR; Genome editing; Computational biology; Biology; Human genome; Genome; Computer science; Genetics; Gene","score_opus":0.011703093945564196,"score_gpt":0.3065583232516798,"score_spread":0.29485522930611563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413051598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7840586,0.18141697,0.032147873,0.0008359233,0.00019090906,0.00087195006,0.000007120103,0.000038760463,0.000431906],"genre_scores_gemma":[0.99114126,0.00491255,0.0028811197,0.0005648855,0.00014898887,0.00019759573,0.000039841038,0.000055374152,0.00005838996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880517,0.00005657087,0.00021778504,0.00046192523,0.00009420978,0.00036434183],"domain_scores_gemma":[0.99949026,0.000017985225,0.00004392777,0.00034530342,0.000050195624,0.00005229851],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021945941,0.00025175288,0.00023572994,0.000108101274,0.00009220908,0.00003919043,0.00020486106,0.00019772908,0.0000030556325],"category_scores_gemma":[0.000017001083,0.00025383916,0.00010134697,0.00008958321,0.00008021856,0.000004180637,0.00008476578,0.00010709456,7.16638e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007947668,0.00009314081,0.0014927002,0.00022312086,0.00020066659,0.00001041136,0.00031020635,0.00008636469,0.91469043,0.0011534861,0.00001724845,0.08164274],"study_design_scores_gemma":[0.00325856,0.0007989142,0.019332474,0.00009460526,0.000040207768,0.000008098254,0.00025112592,0.00039635063,0.8536994,0.0022401724,0.1193798,0.00050032855],"about_ca_topic_score_codex":0.0000036018885,"about_ca_topic_score_gemma":0.000008925785,"teacher_disagreement_score":0.20708267,"about_ca_system_score_codex":0.000017102002,"about_ca_system_score_gemma":0.00002156089,"threshold_uncertainty_score":0.99999136},"labels":[],"label_agreement":null},{"id":"W4414038006","doi":"10.1016/j.omtn.2025.102710","title":"Molecular and imaging biomarker responses to brain mutant HTT lowering in a mouse model of Huntington disease","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"British Columbia Centre of Excellence for Women's Health; University of British Columbia Hospital; Simon Fraser University; BC Children's Hospital; Pacific Centre for Reproductive Medicine; University of British Columbia","funders":"Michael Smith Health Research BC; Children's Health Research Institute; Huntington's Disease Society of America","keywords":"Huntington's disease; Biomarker; Mutant; Neuroscience; Disease; Huntingtin; Imaging biomarker; Biology; Genetics; Medicine; Gene; Pathology; Magnetic resonance imaging","score_opus":0.012041732340733394,"score_gpt":0.27520455256863235,"score_spread":0.26316282022789894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414038006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869589,0.00090202165,0.005839431,0.0053335167,0.000018929402,0.00056858914,0.00001608245,0.000045971286,0.0003165284],"genre_scores_gemma":[0.9894224,0.000084077416,0.0004972913,0.009761319,0.0000018798394,0.00003423403,0.0000053295066,0.000033823835,0.00015963569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878395,0.00007393261,0.0002635057,0.00041563544,0.00018650826,0.00027647923],"domain_scores_gemma":[0.9993589,0.00003983103,0.00004236555,0.00037009016,0.000038823684,0.00015001235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014073173,0.0002128199,0.00031210043,0.00028642605,0.000038751867,0.00002185345,0.00010239873,0.000052033145,0.000012696323],"category_scores_gemma":[0.00015128008,0.00018331136,0.00011068543,0.00031271813,0.0000830435,0.000039800656,0.00009949168,0.0001070581,0.0000020955038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026698664,0.0003884528,0.03632426,0.000039665345,0.00008240756,0.00026600962,0.00010818075,0.00017143965,0.94603056,0.00025659206,0.000013891979,0.013648662],"study_design_scores_gemma":[0.010879162,0.0005701459,0.09316931,0.00038316258,0.00013061533,0.0000037071034,0.00008353879,0.02451695,0.8622071,0.007195899,0.00032005107,0.0005403312],"about_ca_topic_score_codex":0.000032257325,"about_ca_topic_score_gemma":0.0000012980533,"teacher_disagreement_score":0.08382344,"about_ca_system_score_codex":0.00003024551,"about_ca_system_score_gemma":0.00005296572,"threshold_uncertainty_score":0.747522},"labels":[],"label_agreement":null},{"id":"W4414710100","doi":"10.1016/j.omtn.2025.102728","title":"Targeting AASS alleviates neurotoxicity and improves mitochondrial function in astrocyte models for pyridoxine-dependent epilepsy","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"ZonMw","keywords":"Neurotoxicity; Catabolism; Epilepsy; Mitochondrion; Oxidative phosphorylation; Reactive oxygen species; Astrocyte; Induced pluripotent stem cell; Oxidative stress","score_opus":0.006588864687119145,"score_gpt":0.23165358711567802,"score_spread":0.22506472242855888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414710100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83938885,0.005753599,0.15310496,0.00018635896,0.00042454185,0.00090677326,0.00001586076,0.000021367003,0.00019766255],"genre_scores_gemma":[0.9939619,0.0012471222,0.0026973998,0.0013143974,0.00014195642,0.00023198538,0.00009258783,0.000047333597,0.00026535607],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984494,0.000105450796,0.00032875664,0.0006153529,0.00013569767,0.00036538206],"domain_scores_gemma":[0.9994265,0.000015442247,0.00008427014,0.00033704014,0.00006930045,0.00006747608],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020689779,0.0002723004,0.00026214734,0.00009987136,0.000098777586,0.000060324008,0.00021847809,0.00020069806,0.00000863425],"category_scores_gemma":[0.000059193248,0.00026795323,0.00012678416,0.00011470196,0.00007285495,0.000011355706,0.00010880745,0.000115617375,0.0000012551056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00096827035,0.000088780514,0.00062105065,0.000031382064,0.00009054241,0.0000015377524,0.000039080987,0.0021207104,0.9840471,0.0002634714,0.0002894133,0.011438644],"study_design_scores_gemma":[0.009537044,0.00097078935,0.005406835,0.000035064484,0.00007066164,0.000003351101,0.00020223347,0.0116389375,0.9238929,0.0061215814,0.041411992,0.0007085896],"about_ca_topic_score_codex":0.000022896627,"about_ca_topic_score_gemma":0.000012010841,"teacher_disagreement_score":0.154573,"about_ca_system_score_codex":0.000006191691,"about_ca_system_score_gemma":0.000056289606,"threshold_uncertainty_score":0.9999773},"labels":[],"label_agreement":null},{"id":"W4415258664","doi":"10.1016/j.omtn.2025.102744","title":"Innovative aptamer approaches in glial tumor diagnostics and therapy: Progress and future directions","year":2025,"lang":"en","type":"review","venue":"Molecular Therapy — Nucleic Acids","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Ministry of Health of the Russian Federation; Russian Science Foundation","keywords":"Aptamer; Liquid biopsy; Drug delivery; Glioblastoma; Targeted drug delivery; Nucleic acid; Cancer; Cancer treatment","score_opus":0.027182080484445016,"score_gpt":0.2796564511271745,"score_spread":0.2524743706427295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415258664","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0680435,0.9294046,0.000028289256,0.00019959375,0.00042023245,0.0016162083,0.00009467315,0.0001069405,0.00008597134],"genre_scores_gemma":[0.0013218176,0.9964674,0.0009476878,0.0002980894,0.00020669492,0.000602774,0.00003438611,0.00008956849,0.000031594405],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971426,0.00058169314,0.00061073975,0.0008744416,0.00031291816,0.00047759814],"domain_scores_gemma":[0.9987427,0.00023135041,0.00027464825,0.000540265,0.000106662956,0.00010438981],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048440872,0.00063206407,0.0012659138,0.00037999672,0.00016042135,0.00022830044,0.0003673778,0.00030397222,0.00005218162],"category_scores_gemma":[0.000068064866,0.00050398754,0.00013857002,0.0013170516,0.0004800736,0.0001499908,0.00018379714,0.00044139344,0.000015710122],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063013904,0.00024971724,0.00010709174,0.0010921959,0.000097775286,0.000107772554,0.000360355,4.1463085e-7,0.00085238257,0.00053479866,0.000053340296,0.9964811],"study_design_scores_gemma":[0.0012618748,0.0002461503,0.000106756896,0.002192254,0.00011922639,0.00004120935,0.00011140007,0.000013717521,0.003702555,0.00016752744,0.99126375,0.00077355857],"about_ca_topic_score_codex":0.000020077676,"about_ca_topic_score_gemma":0.0000037394782,"teacher_disagreement_score":0.9957076,"about_ca_system_score_codex":0.0000887686,"about_ca_system_score_gemma":0.00029784912,"threshold_uncertainty_score":0.9997412},"labels":[],"label_agreement":null},{"id":"W4415269371","doi":"10.1016/j.omtn.2025.102745","title":"MicroRNA chemical modifications in post-transcriptional gene silencing and human diseases","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Cancer Research Society","keywords":"microRNA; Dicer; Gene silencing; Epigenetics; RNA interference; Regulation of gene expression; Drosha; Crosstalk","score_opus":0.006990582215107306,"score_gpt":0.24701136476933752,"score_spread":0.2400207825542302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415269371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907653,0.0052891625,0.0029968712,0.0003949617,0.00004403789,0.00025833645,0.00004289213,0.000022449009,0.00018601028],"genre_scores_gemma":[0.99788946,0.0001333405,0.0006682032,0.00073355733,0.00004303894,0.000047305,0.00039599216,0.000026055412,0.000063063184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998963,0.000064186526,0.00023046044,0.00042382395,0.00010983771,0.00020869805],"domain_scores_gemma":[0.9994418,0.0000059513604,0.00004451682,0.00035536868,0.00007567984,0.000076707416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006815924,0.00017917385,0.00013758057,0.00010683284,0.00009056041,0.000045469842,0.00018415878,0.00014373676,0.000028725019],"category_scores_gemma":[0.00002083493,0.00019539658,0.000100105186,0.00014734724,0.00012691239,0.000008914646,0.000058528953,0.00008333885,0.0000032625137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008156546,0.0001425667,0.0020631813,0.000014261724,0.00006984579,0.0000046205355,0.00004070703,0.000046142613,0.99481606,0.0011924724,0.00007156762,0.0014569887],"study_design_scores_gemma":[0.0010830334,0.000048797254,0.09853929,0.00002276874,0.000024734385,0.0000061225587,0.000036329344,0.000067147026,0.8977005,0.00066343637,0.0015948006,0.00021304797],"about_ca_topic_score_codex":0.000023196077,"about_ca_topic_score_gemma":0.000005167472,"teacher_disagreement_score":0.09711559,"about_ca_system_score_codex":0.000038904425,"about_ca_system_score_gemma":0.00008036642,"threshold_uncertainty_score":0.7968042},"labels":[],"label_agreement":null},{"id":"W4415909315","doi":"10.1016/j.omtn.2025.102762","title":"Antibacterial activities of novel peptide nucleic acids targeting Salmonella penicillin-binding proteins","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleic acid; Salmonella; Peptide; Peptidoglycan; Antibiotics; Multiple drug resistance; Pathogen; Peptide nucleic acid; Antibacterial activity; Gene","score_opus":0.00833317482796971,"score_gpt":0.24022863016645832,"score_spread":0.2318954553384886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415909315","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873629,0.0009667146,0.0054158396,0.00016419496,0.00039765466,0.000508985,0.00007367719,0.00007666107,0.005033366],"genre_scores_gemma":[0.9921312,0.0003932551,0.0048764306,0.0003916979,0.00026424808,0.000044421027,0.00021487185,0.00012150933,0.0015623999],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973518,0.00009942017,0.00065884617,0.00083949545,0.00037690517,0.00067352626],"domain_scores_gemma":[0.9984527,0.000024383973,0.00032423632,0.00090637855,0.00015802697,0.00013426993],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035824726,0.0005583828,0.00057702453,0.00014733872,0.00023122322,0.00009664428,0.000787327,0.0005076891,0.00012072994],"category_scores_gemma":[0.000116019786,0.0005685483,0.00043901504,0.00033542048,0.0003463531,0.000023745395,0.00035661273,0.00031579498,0.000010402209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064012804,0.00034197464,0.0014015674,0.00009996304,0.0003729694,0.000013388749,0.0001544191,0.00004114714,0.99412835,0.00016237087,0.00056067185,0.002083083],"study_design_scores_gemma":[0.0024084877,0.00030764495,0.00052270974,0.00011055915,0.000049958082,0.00001383029,0.0003173091,0.00008474866,0.9692799,0.000055630207,0.026307102,0.0005421475],"about_ca_topic_score_codex":0.000026791029,"about_ca_topic_score_gemma":0.000001944801,"teacher_disagreement_score":0.02574643,"about_ca_system_score_codex":0.000058015412,"about_ca_system_score_gemma":0.00019959576,"threshold_uncertainty_score":0.9996766},"labels":[],"label_agreement":null},{"id":"W4416427829","doi":"10.1016/j.omtn.2025.102780","title":"mRNA-LNP vaccination orchestrates systemic immunity to control human papillomavirus-positive head and neck squamous cell carcinoma","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"Chengdu Science and Technology Program; National Key Research and Development Program of China; National Key Research and Development Program of China Stem Cell and Translational Research; Sichuan University; Chengdu Science and Technology Bureau; West China Hospital, Sichuan University; Department of Science and Technology of Sichuan Province; National Natural Science Foundation of China","keywords":"Immune system; Vaccination; Immunotherapy; Head and neck squamous-cell carcinoma; Innate immune system; Immunity; Acquired immune system; Tumor microenvironment","score_opus":0.007849051683796512,"score_gpt":0.25141469294507246,"score_spread":0.24356564126127594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416427829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98999715,0.0047798576,0.0023588273,0.00018631817,0.00010307875,0.0005924289,0.000029547266,0.000027223166,0.0019255845],"genre_scores_gemma":[0.9970895,0.00018070849,0.00010032813,0.001864321,0.000053494525,0.00006549117,0.000090614994,0.00003575388,0.0005197961],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852717,0.00021065652,0.00030253644,0.000499422,0.00013134246,0.00032889217],"domain_scores_gemma":[0.99909025,0.000016482087,0.00008606711,0.00051698973,0.00018309083,0.00010709843],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017317067,0.00030608726,0.00028207863,0.000116656054,0.00021555227,0.00008933432,0.00032783224,0.00023320364,0.000020100899],"category_scores_gemma":[0.000020410187,0.00030067924,0.00012938962,0.00016095169,0.00004828878,0.000010519161,0.000106148866,0.00016265531,0.000017751163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003591946,0.00011024523,0.007646632,0.000028993476,0.00007528969,0.000019051624,0.00017892738,0.00004602614,0.9858988,0.00010853638,0.00024046774,0.005287831],"study_design_scores_gemma":[0.0029079977,0.0014756379,0.07405077,0.0000413194,0.00004007294,0.000017792445,0.00020950778,0.00006443486,0.9196428,0.00015409799,0.0010396614,0.00035589188],"about_ca_topic_score_codex":0.00019316211,"about_ca_topic_score_gemma":0.000024518162,"teacher_disagreement_score":0.066404134,"about_ca_system_score_codex":0.000044119744,"about_ca_system_score_gemma":0.00006726841,"threshold_uncertainty_score":0.9999445},"labels":[],"label_agreement":null},{"id":"W4417165511","doi":"10.1016/j.omtn.2025.102790","title":"Aptamer-based approaches for sensitive detection and epitope mapping of SARS-CoV-2 spike protein","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Aptamer; Epitope; Stacking; DNA; Nucleic acid; Systematic evolution of ligands by exponential enrichment; Peptide; Epitope mapping; Binding selectivity; Protein–protein interaction","score_opus":0.023910641997524112,"score_gpt":0.2733425290875797,"score_spread":0.24943188709005562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417165511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71544844,0.00037134023,0.28336087,0.0001704275,0.000019333098,0.0004781087,0.000010094759,0.000030093266,0.00011130094],"genre_scores_gemma":[0.9717849,0.00006581102,0.02742653,0.0005353891,0.000028916065,0.000051785886,0.000034329852,0.000025557774,0.00004676627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989769,0.00008272629,0.00023209937,0.00042208805,0.00009156548,0.00019466248],"domain_scores_gemma":[0.9993949,0.000010053572,0.00012418738,0.00032781114,0.000120794815,0.000022286275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020842683,0.00020532066,0.00024802313,0.00012388855,0.000090850015,0.000019897483,0.00010028557,0.00019802406,1.3614422e-7],"category_scores_gemma":[0.000047068766,0.00018847472,0.00017468666,0.00019956636,0.00018015437,0.000004046736,0.000044684297,0.00007615633,1.8215162e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024696783,0.00005467284,0.000031265925,0.00003597815,0.00013626246,0.0000014202305,0.000015771499,0.000005700944,0.9222626,0.00009146393,0.000011229908,0.077106655],"study_design_scores_gemma":[0.0006861273,0.00036241123,0.00012206228,0.0000489954,0.000029291836,0.0000024664787,0.00006539851,0.0010727517,0.99154294,0.00041171457,0.005458436,0.00019741517],"about_ca_topic_score_codex":0.000012553318,"about_ca_topic_score_gemma":0.000007267415,"teacher_disagreement_score":0.25633648,"about_ca_system_score_codex":0.000015732872,"about_ca_system_score_gemma":0.00003590564,"threshold_uncertainty_score":0.7685776},"labels":[],"label_agreement":null},{"id":"W7110944318","doi":"10.1016/j.omtn.2025.102791","title":"DUX4 reduction and muscle function improvement by subcutaneous delivery of gapmer antisense oligonucleotides","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"FSH Society; Muscular Dystrophy Association","keywords":"Facioscapulohumeral muscular dystrophy; Gene knockdown; Oligonucleotide; Messenger RNA; Skeletal muscle; Muscular dystrophy; Nucleic acid; Downregulation and upregulation","score_opus":0.0032854179014177296,"score_gpt":0.20769696461620682,"score_spread":0.2044115467147891,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7110944318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300444,0.0044017094,0.0014555699,0.00019166904,0.00017004485,0.00024163867,0.000011897707,0.000020722204,0.00050229585],"genre_scores_gemma":[0.99636394,0.0024589773,0.00011176605,0.00073374767,0.000026992499,0.00001638773,0.00007839308,0.000022944721,0.0001868312],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990401,0.000069061156,0.00021340273,0.00038948737,0.00008617397,0.00020175384],"domain_scores_gemma":[0.9994739,0.0000059185236,0.00008337259,0.00033155427,0.000060577746,0.000044631437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009069576,0.00018238238,0.00017178671,0.000058951748,0.00009602368,0.0000134358625,0.00010627706,0.00017597433,0.000031015697],"category_scores_gemma":[0.000009332634,0.00018329154,0.000098000855,0.00010679003,0.00018094428,0.0000065144686,0.00006696009,0.00007806495,0.000002717728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075416773,0.000114833674,0.00020249849,0.000021848547,0.00015963582,0.0000024917438,0.000023317143,0.000022242306,0.9511623,0.00022215508,0.0011050064,0.046209518],"study_design_scores_gemma":[0.0012007903,0.0012104401,0.0033994436,0.000015830625,0.000043409924,0.000008427219,0.00012369208,0.000038758928,0.97738,0.0007611015,0.01559458,0.0002235339],"about_ca_topic_score_codex":0.000057716967,"about_ca_topic_score_gemma":0.0000025616396,"teacher_disagreement_score":0.045985986,"about_ca_system_score_codex":0.000009253662,"about_ca_system_score_gemma":0.00002924192,"threshold_uncertainty_score":0.74744123},"labels":[],"label_agreement":null},{"id":"W7117869988","doi":"10.1016/j.omtn.2025.102815","title":"Atrophin-1 antisense oligonucleotide provides robust protection from pathology in a fully humanized DRPLA model","year":2025,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Movement Disorders","funders":"","keywords":"Humanized mouse; Human disease; Gene knockdown; Phenotype; Untranslated region; Trinucleotide repeat expansion; Oligonucleotide; Gene knockin; Loss function","score_opus":0.028505041121258855,"score_gpt":0.2550215955443463,"score_spread":0.22651655442308744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117869988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9677236,0.00030754233,0.028905552,0.00077372376,0.0002587392,0.0013757994,0.00003759391,0.00020075041,0.00041671377],"genre_scores_gemma":[0.99258727,0.00016048709,0.0026540894,0.003965939,0.000033568125,0.00023163966,0.0000085301035,0.00007930798,0.00027914622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99679846,0.0007341542,0.00046134403,0.0011528691,0.0003344245,0.00051876693],"domain_scores_gemma":[0.99887145,0.00005833705,0.0001379515,0.00077485084,0.00005955151,0.00009786359],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014706196,0.0004082925,0.000409539,0.00033607415,0.00021804615,0.00013179357,0.00051717117,0.00015802318,0.00005046446],"category_scores_gemma":[0.0003234686,0.0004078449,0.00018307428,0.0006154883,0.00024501845,0.00014288432,0.00015407697,0.00034075335,0.00005083521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043367612,0.00027403777,0.0003269571,0.000011432396,0.000015892982,0.00034999655,0.0002546307,0.010491989,0.98188627,0.0009517597,0.000055589124,0.004947791],"study_design_scores_gemma":[0.0024151308,0.00018480288,0.0032325506,0.00003841817,0.00002055866,0.000011774588,0.000032304633,0.039008062,0.9488494,0.005578716,0.0002743772,0.00035394347],"about_ca_topic_score_codex":0.00008262366,"about_ca_topic_score_gemma":0.000025058258,"teacher_disagreement_score":0.033036888,"about_ca_system_score_codex":0.00009148795,"about_ca_system_score_gemma":0.00015799978,"threshold_uncertainty_score":0.99983734},"labels":[],"label_agreement":null}]}