{"meta":{"query_hash":"96edc2010054","filters":{"venue":"Pharmaceutical Research"},"cohort_total":236,"direct_labels_cover":1,"predictions_cover":236,"exported":236,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/96edc2010054","api":"https://metacan.xera.ac/api/v1/cohort?venue=Pharmaceutical+Research"},"results":[{"id":"W112168112","doi":"10.1023/a:1007521016985","title":"Sensitivity of Empirical Metrics of Rate of Absorption in Bioequivalence Studies","year":2000,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Deutsche Forschungsgemeinschaft","keywords":"Bioequivalence; Mathematics; Sensitivity (control systems); Absorption (acoustics); Statistics; Analytical Chemistry (journal); Dispersion (optics); Chemistry; Pharmacokinetics; Chromatography; Physics; Pharmacology; Medicine; Optics","score_opus":0.9449494173068114,"score_gpt":0.7713117230809766,"score_spread":0.17363769422583475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W112168112","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":"methods","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":"methods","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10540779,0.00953135,0.8762519,0.003646932,0.0002335889,0.00029024237,0.0006617888,0.0007330331,0.003243432],"genre_scores_gemma":[0.8930518,0.0025500394,0.10067417,0.0010736763,0.0003159688,0.00047367756,0.00057941675,0.0004321517,0.0008489927],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.79706216,0.17833003,0.0062297173,0.007414716,0.009827654,0.0011357765],"domain_scores_gemma":[0.12225193,0.8374577,0.015675936,0.019793482,0.003987639,0.00083334453],"candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.1903698,0.002220449,0.0044270307,0.0044486416,0.0006359196,0.00606981,0.00323256,0.0047484008,0.001914098],"category_scores_gemma":[0.6828747,0.0016650114,0.0030765936,0.0026692853,0.00639969,0.008860159,0.005553674,0.006572186,0.0002913859],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030788046,0.00030664663,0.03853534,0.0021737756,0.004398834,0.0006410409,0.0010029632,0.58022994,0.0026782735,0.25213125,0.0036577245,0.11116535],"study_design_scores_gemma":[0.00013839184,0.0008237023,0.008602625,0.00031539332,0.00056235935,0.0009887854,0.00012077614,0.66271585,0.0031260294,0.32003543,0.0024280548,0.00014263598],"about_ca_topic_score_codex":0.001039939,"about_ca_topic_score_gemma":0.0003684296,"teacher_disagreement_score":0.8096302,"about_ca_system_score_codex":0.0035040365,"about_ca_system_score_gemma":0.0018485361,"threshold_uncertainty_score":0.99841815},"labels":[],"label_agreement":null},{"id":"W112529225","doi":"10.1023/a:1026147620304","title":"Use of a Physiologic Bicarbonate Buffer System for Dissolution Characterization of Ionizable Drugs","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Purdue Pharma (Canada)","funders":"University of Connecticut; Boehringer Ingelheim","keywords":"Dissolution; Sparging; Chemistry; Bicarbonate; Solubility; Chromatography; Dipyridamole; Buffer solution; Aqueous solution; Nuclear chemistry; Organic chemistry","score_opus":0.46905080587925935,"score_gpt":0.525340806961247,"score_spread":0.05629000108198762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W112529225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87801075,0.00426341,0.113302864,0.00043753552,0.00015854219,0.0005633844,0.00044738202,0.0003548314,0.0024612818],"genre_scores_gemma":[0.86980397,0.00413037,0.12099905,0.0003114804,0.000033900844,0.00033301485,0.0010422308,0.00014943196,0.0031965172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996344,0.00005520925,0.000053147414,0.000101235746,0.00011585746,0.000040167197],"domain_scores_gemma":[0.9995714,0.00013102427,0.0000829814,0.000041997137,0.00012877733,0.000043870812],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088816247,0.0005333689,0.0005217104,0.00031930557,0.00037769947,0.0005849191,0.00045605892,0.00053638505,0.0008160632],"category_scores_gemma":[0.00080757594,0.00022513261,0.00027848355,0.00030164586,0.00035179543,0.0007965186,0.00031160057,0.00058234914,0.000352084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007829252,0.000016140279,0.0001066983,0.000043990054,0.0000036384113,0.000016794173,0.000017008577,0.000022966035,0.998038,0.00005324411,0.0000150418855,0.0015881527],"study_design_scores_gemma":[0.0000053047092,0.000081570215,0.00021773993,0.0000025347993,0.0000072774596,0.000055201643,0.000006223732,0.00022267403,0.9986695,0.00001072006,0.00071806886,0.0000031725085],"about_ca_topic_score_codex":0.0010921698,"about_ca_topic_score_gemma":0.0010681994,"teacher_disagreement_score":0.0010921698,"about_ca_system_score_codex":0.00033488817,"about_ca_system_score_gemma":0.00074226735,"threshold_uncertainty_score":0.004697144},"labels":[],"label_agreement":null},{"id":"W1244009314","doi":"10.1023/a:1015127225021","title":"Block Copolymer Micelles for the Encapsulation and Delivery of Amphotericin B","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Ministry of Health and Medical Education; Provincial Health Services Authority","keywords":"Stearic acid; Micelle; Chemistry; Hemolysis; Amphotericin B; Aspergillus fumigatus; Candida albicans; Organic chemistry; Stereochemistry; Aqueous solution; Microbiology; Biology; Antifungal","score_opus":0.2624487176425075,"score_gpt":0.4333755830719957,"score_spread":0.1709268654294882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1244009314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94606286,0.016526446,0.03054251,0.00047112047,0.000206699,0.000118359036,0.00016924151,0.000358738,0.005543968],"genre_scores_gemma":[0.96268487,0.0074948943,0.017985439,0.00012196336,0.0000476563,0.00008470647,0.00019173262,0.000074044394,0.011314681],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992263,0.000013270204,0.000007014568,0.000012142935,0.000030720326,0.0000141046285],"domain_scores_gemma":[0.9999435,0.000012417671,0.000018936676,0.000004168831,0.0000095806745,0.000011466948],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023552017,0.00023622904,0.00014887424,0.00021758841,0.00015759066,0.00022976879,0.00014459161,0.00031835688,0.001072415],"category_scores_gemma":[0.00020027242,0.0002214734,0.00013053422,0.000100706704,0.00011997814,0.0005006727,0.00021399872,0.0004064919,0.0005402041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007336482,0.000018121355,0.000025828273,0.000047374488,0.000003768922,0.000024114142,0.000010011076,0.0001375176,0.99534684,0.00036572956,0.00010627732,0.003840995],"study_design_scores_gemma":[0.000029330047,0.00016500615,0.00026146523,0.0000061328856,0.000013008751,0.00012729377,0.0000047781778,0.0017414708,0.99183124,0.0000758844,0.005738201,0.0000061597666],"about_ca_topic_score_codex":0.00034416973,"about_ca_topic_score_gemma":0.00052831846,"teacher_disagreement_score":0.001072415,"about_ca_system_score_codex":0.00023291344,"about_ca_system_score_gemma":0.00022972697,"threshold_uncertainty_score":0.003587544},"labels":[],"label_agreement":null},{"id":"W125790724","doi":"10.1023/a:1016125420577","title":"New Methods Characterizing Avalanche Behavior to Determine Powder Flow","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Microencapsulation and Drying Processes","field":"Agricultural and Biological Sciences","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"TransCanada (Canada); Merck Canada Inc. (Canada); Université de Montréal","funders":"","keywords":"Angle of repose; Materials science; Excipient; Maltodextrin; Composite material; Mineralogy; Chromatography; Chemistry","score_opus":0.4500694023833444,"score_gpt":0.5056010496939847,"score_spread":0.05553164731064025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W125790724","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0998063,0.006015815,0.8859901,0.00019470646,0.00025930782,0.000530427,0.0004616763,0.0016367658,0.0051049353],"genre_scores_gemma":[0.31542984,0.004678363,0.6669466,0.00032419735,0.00011496578,0.0010708048,0.00061087485,0.00024612775,0.010578335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901354,0.00008772716,0.000059756872,0.00021694694,0.00056014484,0.00006187458],"domain_scores_gemma":[0.9972742,0.0012202333,0.00039923043,0.00028698888,0.0007055131,0.000113859904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016048844,0.0010006932,0.0005762912,0.0024842576,0.0005094509,0.0009401485,0.0009049347,0.00089126086,0.0023533604],"category_scores_gemma":[0.0018585224,0.00072954124,0.00038038642,0.0009494609,0.0007378679,0.0020700307,0.0006582152,0.0022705044,0.0007414974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084358915,0.00009764048,0.0012412636,0.0002485526,0.000020900916,0.000029814835,0.000104513754,0.00020781632,0.964655,0.0012048116,0.00024590368,0.03185937],"study_design_scores_gemma":[0.000019339232,0.00013668033,0.0023833348,0.000019777637,0.00003354227,0.00022299572,0.000044445696,0.009057911,0.98272705,0.0005245696,0.0048002247,0.000030126566],"about_ca_topic_score_codex":0.0005847664,"about_ca_topic_score_gemma":0.0016386595,"teacher_disagreement_score":0.0024842576,"about_ca_system_score_codex":0.00077415357,"about_ca_system_score_gemma":0.0004927135,"threshold_uncertainty_score":0.008487523},"labels":[],"label_agreement":null},{"id":"W144463279","doi":"10.1023/a:1022215228799","title":"Modifications in Lipoprotein Surface Charge Alter Cyclosporine A Association with Low-Density Lipoproteins","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Oral and gingival health research","field":"Health Professions","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Lipoprotein; Association (psychology); Chemistry; Low-density lipoprotein; Pharmacology; Medicine; Biochemistry; Cholesterol; Psychology","score_opus":0.27204230646187055,"score_gpt":0.5620598223840048,"score_spread":0.2900175159221342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W144463279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.999153,0.0001940906,0.00022625302,0.00004297901,0.000018460256,0.0000044481026,0.00005813152,0.000010479058,0.00029199984],"genre_scores_gemma":[0.99895835,0.00011541872,0.00014385463,0.000040187715,0.000014855566,0.000003942634,0.000114183975,0.0000101759415,0.0005989729],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997434,0.00008171978,0.000024384655,0.000038562026,0.000036168713,0.000075746786],"domain_scores_gemma":[0.99928904,0.00024043012,0.00014431689,0.00008536763,0.00007500247,0.00016578914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002738895,0.00024913345,0.00027223167,0.00030322277,0.00035154,0.00056462386,0.00025341188,0.0004723647,0.0033275352],"category_scores_gemma":[0.0006979902,0.00022482949,0.000384076,0.0003426665,0.00034385273,0.0002781508,0.00019548448,0.0005156821,0.00050248613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0051222616,0.0001783283,0.004949836,0.000037942296,0.00007969792,0.00017408804,0.0000749906,0.000076271994,0.98689854,0.000099569304,0.000098593126,0.0022099172],"study_design_scores_gemma":[0.00027633045,0.0014088566,0.08128846,0.000010163162,0.00014415543,0.000736558,0.00023579398,0.0014661677,0.9128783,0.0001134695,0.0014161597,0.000025574196],"about_ca_topic_score_codex":0.0019726634,"about_ca_topic_score_gemma":0.0012679802,"teacher_disagreement_score":0.0033275352,"about_ca_system_score_codex":0.0003190527,"about_ca_system_score_gemma":0.00024639984,"threshold_uncertainty_score":0.011131763},"labels":[],"label_agreement":null},{"id":"W1486915463","doi":"10.1023/a:1014434732752","title":"Use of the Post-Insertion Technique to Insert Peptide Ligands into Pre-Formed Stealth Liposomes with Retention of Binding Activity and Cytotoxicity","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":155,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Liposome; Cytotoxicity; Chemistry; Peptide; Doxorubicin; MTT assay; Ethylene glycol; PEG ratio; In vitro; Phospholipid; Biophysics; Biochemistry; Membrane; Biology; Organic chemistry","score_opus":0.14693587555684065,"score_gpt":0.3942198387025167,"score_spread":0.24728396314567605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1486915463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9176666,0.0011616659,0.07742896,0.00022791357,0.00010038353,0.00020239719,0.00017015457,0.00036033813,0.0026814654],"genre_scores_gemma":[0.9407911,0.0009103639,0.051860895,0.00015585306,0.000026421958,0.00012233258,0.0003945236,0.000117203745,0.0056211916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998505,0.000026760199,0.000016800828,0.00003286733,0.0000416938,0.00003136917],"domain_scores_gemma":[0.99972254,0.000075936434,0.000070677204,0.00006576322,0.0000405619,0.000024502402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034387864,0.0005536083,0.00032430567,0.00015193115,0.00021283884,0.0003198119,0.00042004453,0.0005730396,0.0007364752],"category_scores_gemma":[0.00035080544,0.00031537618,0.00039778205,0.00015651334,0.00031533648,0.00054842356,0.00029332362,0.00094940246,0.00068457704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040501116,0.0000120713585,0.00002849403,0.0000167984,0.0000027272906,0.00002617406,0.000007940627,0.000022759621,0.99888164,0.00007106581,0.000009123443,0.0008806195],"study_design_scores_gemma":[0.0000028758209,0.00005658277,0.0001363799,4.821988e-7,0.000004185648,0.000090068475,0.0000011800197,0.0000909815,0.9992404,0.0000074397676,0.00036772035,0.0000016809122],"about_ca_topic_score_codex":0.00036164347,"about_ca_topic_score_gemma":0.0004333633,"teacher_disagreement_score":0.0007364752,"about_ca_system_score_codex":0.0001782368,"about_ca_system_score_gemma":0.0002973486,"threshold_uncertainty_score":0.002463758},"labels":[],"label_agreement":null},{"id":"W1487014217","doi":"10.1023/a:1020452531828","title":"Analysis of Poly(D,L-Lactic-Co-Glycolic Acid) Nanosphere Uptake by Human Dendritic Cells and Macrophages In Vitro","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":160,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Blood Services","keywords":"Glycolic acid; In vitro; Chemistry; Lactic acid; Biochemistry; Molecular biology; Biology; Bacteria","score_opus":0.08213119758383586,"score_gpt":0.4072311290854972,"score_spread":0.32509993150166133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1487014217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99421364,0.00094555086,0.0030564978,0.000044535187,0.000013306474,0.000031520238,0.00023318041,0.000026564709,0.0014353181],"genre_scores_gemma":[0.99349964,0.00057337334,0.0030622021,0.000037699778,0.000010885072,0.000057923895,0.0002932901,0.000024711342,0.0024403972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998809,0.000016988562,0.000009779902,0.000024900442,0.0000344748,0.000033002074],"domain_scores_gemma":[0.99988484,0.00005744133,0.00000899251,0.000010887228,0.000027791302,0.00001007025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016983386,0.00019852899,0.00022385048,0.00015570225,0.00017590736,0.00019916678,0.00011989901,0.00026057992,0.00053220266],"category_scores_gemma":[0.00015586015,0.00013441681,0.00021670992,0.00012929097,0.0001390305,0.0002027935,0.0001298399,0.0002436985,0.00029577038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000645558,0.000009981216,0.0001207501,0.000020914775,0.0000023542364,0.00003021993,0.000023512825,0.000033698525,0.9991128,0.000021326814,0.0000100598645,0.00054979685],"study_design_scores_gemma":[0.0000058154637,0.00007143554,0.0022280752,0.0000017977159,0.000007584397,0.000056103134,0.000018471286,0.00048593542,0.9967417,0.00001514095,0.00036558972,0.0000022720687],"about_ca_topic_score_codex":0.0012637813,"about_ca_topic_score_gemma":0.0012412788,"teacher_disagreement_score":0.0012637813,"about_ca_system_score_codex":0.00021577034,"about_ca_system_score_gemma":0.00015830196,"threshold_uncertainty_score":0.0025128722},"labels":[],"label_agreement":null},{"id":"W1498814102","doi":"10.1023/a:1025009300562","title":"Interaction of Differently Designed Immunoliposomes with Colon Cancer Cells and Kupffer Cells. An in Vitro Comparison","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Leids Universitair Medisch Centrum; KWF Kankerbestrijding","keywords":"Liposome; In vitro; Chemistry; Antibody; Receptor; PEG ratio; Biophysics; Scavenger receptor; Monoclonal antibody; Biochemistry; Molecular biology; Biology; Immunology; Cholesterol; Lipoprotein","score_opus":0.1239581509132498,"score_gpt":0.43684732856043534,"score_spread":0.31288917764718555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1498814102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99346405,0.002452955,0.0022889746,0.000062034225,0.000043131287,0.00004151734,0.00013720382,0.000014052792,0.0014961367],"genre_scores_gemma":[0.99313724,0.0015313851,0.0031258373,0.00007215138,0.00001148823,0.000045033994,0.00044370917,0.000015512314,0.0016176864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996699,0.0000989248,0.00003157045,0.00004729862,0.00005383754,0.00009839657],"domain_scores_gemma":[0.9997143,0.00015825627,0.00002926654,0.000027684333,0.00004406453,0.00002632202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004863609,0.00034525353,0.00032375086,0.00017302137,0.00021044999,0.00033810202,0.00020150866,0.00045045748,0.0009495192],"category_scores_gemma":[0.00042647426,0.00021710989,0.000390414,0.00016196871,0.00020864382,0.00033407917,0.00021195911,0.00038375976,0.00034483892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022884128,0.00004412792,0.0002145867,0.00008959358,0.000011717684,0.000052889405,0.000042622316,0.000078902,0.9983646,0.00006872916,0.000023875982,0.00077948964],"study_design_scores_gemma":[0.000014425473,0.00039127574,0.001393032,0.000008506249,0.000023539857,0.00011642915,0.000030820338,0.00033742917,0.9967704,0.000014037147,0.00089569075,0.000004468739],"about_ca_topic_score_codex":0.0012745532,"about_ca_topic_score_gemma":0.0017873674,"teacher_disagreement_score":0.0012745532,"about_ca_system_score_codex":0.0003894384,"about_ca_system_score_gemma":0.0002546828,"threshold_uncertainty_score":0.0031765103},"labels":[],"label_agreement":null},{"id":"W1502923912","doi":"10.1023/a:1007524919865","title":"The Stereoselective Distribution of Halofantrine Enantiomers Within Human, Dog, and Rat Plasma Lipoproteins","year":2000,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Diabetes, Cardiovascular Risks, and Lipoproteins","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Halofantrine; Enantiomer; Chemistry; Stereoselectivity; Pharmacokinetics; Lipoprotein; Chromatography; Triglyceride; Pharmacology; Cholesterol; Stereochemistry; Biochemistry; Biology","score_opus":0.07442076399745046,"score_gpt":0.4208222380360085,"score_spread":0.34640147403855803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1502923912","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959454,0.001518593,0.0010566846,0.000097624135,0.000012409801,0.0000083036875,0.0001345477,0.000022283173,0.0012041397],"genre_scores_gemma":[0.99714833,0.0012153764,0.00056746503,0.00007990563,0.000020021416,0.000010503591,0.00012598032,0.000010954533,0.0008214995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998975,0.000038342463,0.0000060519346,0.000025355006,0.000013861977,0.00001893102],"domain_scores_gemma":[0.99982494,0.00007273304,0.000035692374,0.000023522922,0.0000142228,0.000028966875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031873496,0.00021228474,0.00018527273,0.00038994852,0.00015780689,0.00032332368,0.00010107613,0.00033670876,0.0010434227],"category_scores_gemma":[0.00045731547,0.00022803983,0.00017499544,0.00012744489,0.00041447574,0.00032053352,0.00010769694,0.0003887122,0.00026702238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012632624,0.00007738095,0.0067852964,0.000060586877,0.00008288047,0.00049967406,0.000270152,0.00022438291,0.9577517,0.0012099426,0.00018675481,0.020218523],"study_design_scores_gemma":[0.00036621353,0.0031485916,0.08576348,0.000024786583,0.00021061343,0.003670497,0.00036916623,0.0014274098,0.9000592,0.00072624953,0.004188243,0.000045572986],"about_ca_topic_score_codex":0.0009343246,"about_ca_topic_score_gemma":0.00053983764,"teacher_disagreement_score":0.0010434227,"about_ca_system_score_codex":0.00021505663,"about_ca_system_score_gemma":0.00023694387,"threshold_uncertainty_score":0.0034905672},"labels":[],"label_agreement":null},{"id":"W1510956999","doi":"10.1023/a:1015341726183","title":"In Vitro Characterization of Hepatic Flavopiridol Metabolism Using Human Liver Microsomes and Recombinant UGT Enzymes","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"In vitro; Microsome; Enzyme; Recombinant DNA; Biochemistry; Chemistry; Metabolism; Human liver; Liver enzyme; Pharmacology; Biology; Endocrinology; Gene","score_opus":0.41966555515645854,"score_gpt":0.5384143441943517,"score_spread":0.11874878903789321,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1510956999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97505885,0.0046440368,0.017197698,0.00021232708,0.00005691037,0.00009473133,0.0013657844,0.00017501765,0.0011945455],"genre_scores_gemma":[0.98701036,0.0015784017,0.0060759997,0.000047901423,0.000030343963,0.00004310629,0.0032459148,0.000045918536,0.0019219866],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978536,0.00008691736,0.000019559644,0.00003164442,0.0000397455,0.000036874724],"domain_scores_gemma":[0.99979156,0.00009607218,0.000026467187,0.000039340885,0.000030497176,0.000016069673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004737457,0.0005100065,0.0004248753,0.00030737947,0.0002364537,0.00034023807,0.00020286236,0.00027247213,0.0008833867],"category_scores_gemma":[0.00059342076,0.00022881101,0.00042576625,0.00038848532,0.00023082145,0.000316865,0.00012944888,0.00057989074,0.00046047903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014148267,0.00014046862,0.0009967816,0.00008596499,0.00005713318,0.00017804003,0.00005054995,0.0007698107,0.9917024,0.0002487529,0.00013278505,0.0042225653],"study_design_scores_gemma":[0.000039277966,0.0004096017,0.0025919504,0.0000032489884,0.000056099834,0.0003068205,0.000020732783,0.0016548331,0.9937645,0.00006447606,0.0010812191,0.0000071196737],"about_ca_topic_score_codex":0.0035012534,"about_ca_topic_score_gemma":0.0034629316,"teacher_disagreement_score":0.0035012534,"about_ca_system_score_codex":0.0005158202,"about_ca_system_score_gemma":0.00033343196,"threshold_uncertainty_score":0.006961763},"labels":[],"label_agreement":null},{"id":"W1513115519","doi":"10.1023/a:1013062600566","title":"Workshop on Bioanalytical Methods Validation for Macromolecules: Summary Report","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Bioanalysis; Pharmaceutical technology; Computational biology; Chemistry; Nanotechnology; Biochemical engineering; Computer science; Biology; Chromatography; Engineering; Materials science","score_opus":0.2503392469700353,"score_gpt":0.5683573208793601,"score_spread":0.3180180739093248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1513115519","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10254998,0.21270631,0.38621476,0.06679756,0.07112759,0.011524888,0.009008406,0.003511118,0.13655938],"genre_scores_gemma":[0.17554821,0.09374247,0.10128614,0.017229225,0.018797044,0.0049685044,0.017050046,0.0018184704,0.5695599],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9951615,0.00093441515,0.0003561713,0.0007147686,0.0018156621,0.0010175068],"domain_scores_gemma":[0.9944687,0.0005027895,0.00027542445,0.00036117458,0.0032202364,0.0011716859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01224838,0.0028319722,0.001770824,0.002659157,0.0023405366,0.003393821,0.0033349318,0.0069234455,0.015412406],"category_scores_gemma":[0.0033970498,0.0010561731,0.0024341375,0.0015948883,0.0008673072,0.0025778066,0.004213875,0.0035689638,0.01361541],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034419643,0.0023800184,0.0022763722,0.005227668,0.0005270327,0.0018751617,0.001538368,0.0039917855,0.28784958,0.0069281217,0.27570605,0.40825784],"study_design_scores_gemma":[0.00017741922,0.0020487034,0.0031366542,0.00067547406,0.00027473934,0.0009248309,0.00041253606,0.0011210118,0.22541344,0.0023089426,0.76339394,0.0001123655],"about_ca_topic_score_codex":0.004088823,"about_ca_topic_score_gemma":0.0056311567,"teacher_disagreement_score":0.015412406,"about_ca_system_score_codex":0.0021448794,"about_ca_system_score_gemma":0.007904001,"threshold_uncertainty_score":0.06477642},"labels":[],"label_agreement":null},{"id":"W1515542254","doi":"10.1023/a:1007669411738","title":"Bioanalytical Method Validation—A Revisit with a Decade of Progress","year":2000,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":1571,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Purdue Pharma (Canada); University of Saskatchewan","funders":"","keywords":"Bioanalysis; Data science; Computer science; Computational biology; Nanotechnology; Biochemical engineering; Engineering ethics; Biology; Engineering; Materials science","score_opus":0.17049249684697565,"score_gpt":0.5186894285672768,"score_spread":0.3481969317203012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1515542254","genre_codex":"review","genre_gemma":"methods","domain_codex":null,"domain_gemma":"methods","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":null,"domain_candidate":"methods","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0023796465,0.8871344,0.046728607,0.04823838,0.011246768,0.0002597542,0.00015064175,0.0005566343,0.003305188],"genre_scores_gemma":[0.021951344,0.8030343,0.095409155,0.048341475,0.02317187,0.0002900764,0.00057161803,0.0004927073,0.0067374753],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9498542,0.01280222,0.009391985,0.0057325857,0.02125984,0.0009591557],"domain_scores_gemma":[0.79295045,0.11045306,0.006610642,0.011790506,0.07457184,0.0036234353],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.13611428,0.0046479837,0.006403918,0.011783483,0.0029274598,0.0128138475,0.009210793,0.011606636,0.0015578646],"category_scores_gemma":[0.0664339,0.0025043825,0.0031627107,0.0061486317,0.01828221,0.017436316,0.00640651,0.01668626,0.0028264285],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017588904,0.0005993513,0.0028026742,0.0094206035,0.00033398412,0.00033135028,0.0008145672,0.0007325482,0.006543387,0.0118988715,0.047608912,0.91873777],"study_design_scores_gemma":[0.00015245206,0.0010093997,0.0061356626,0.008788722,0.0005043488,0.005024616,0.0015216455,0.0034289698,0.016824586,0.030391753,0.9257249,0.0004930162],"about_ca_topic_score_codex":0.0059617637,"about_ca_topic_score_gemma":0.00810727,"teacher_disagreement_score":0.8638857,"about_ca_system_score_codex":0.0067168437,"about_ca_system_score_gemma":0.01985174,"threshold_uncertainty_score":0.7198497},"labels":[],"label_agreement":null},{"id":"W1516278151","doi":"10.1023/a:1026466730347","title":"A Population Analysis of Nebulized (R)-albuterol in Dogs Using a Novel Mixed Gut-Lung Absorption PK-PD Model","year":2000,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Pharmacological Effects and Assays","field":"Agricultural and Biological Sciences","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BioPhage Pharma (Canada); Pharmaxis (Canada); Université de Montréal","funders":"","keywords":"Pharmacokinetics; Absorption (acoustics); Population; Chemistry; Pharmacodynamics; Bioavailability; Bronchodilator; Pharmacology; Medicine; Anesthesia; Chromatography; Internal medicine; Asthma; Materials science","score_opus":0.2583208899119437,"score_gpt":0.4702723309576077,"score_spread":0.211951441045664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1516278151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99363977,0.00008582365,0.005803459,0.000017806005,0.0000021593517,0.00005643895,0.00014765114,0.000025247125,0.00022173264],"genre_scores_gemma":[0.9964128,0.00008935022,0.0024992484,0.000028786586,0.0000055453183,0.00010175526,0.00033512295,0.000015003435,0.0005123048],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9995431,0.00014584667,0.00001713209,0.00015901779,0.00007839107,0.00005652401],"domain_scores_gemma":[0.999613,0.00015334772,0.00008508892,0.000053254244,0.00004756048,0.00004785102],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00087108015,0.00028762745,0.0008196052,0.00038541105,0.00024956922,0.00042032872,0.00028384925,0.00048101772,0.0008448911],"category_scores_gemma":[0.000966378,0.00021927578,0.00036824017,0.00021448938,0.0003010655,0.00028961943,0.00031056313,0.00051570986,0.00020279504],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029047929,0.0026858812,0.24554965,0.00018638723,0.0007391342,0.0009188583,0.0009565368,0.018892067,0.6293994,0.0020977827,0.0010516974,0.06847456],"study_design_scores_gemma":[0.0008440756,0.038784143,0.6062639,0.000022240962,0.0011293121,0.003710088,0.0008848515,0.21782959,0.12380797,0.0016342574,0.0049236,0.00016607977],"about_ca_topic_score_codex":0.0023662657,"about_ca_topic_score_gemma":0.0014919911,"teacher_disagreement_score":0.0023662657,"about_ca_system_score_codex":0.0004111032,"about_ca_system_score_gemma":0.0003913409,"threshold_uncertainty_score":0.0047049522},"labels":[],"label_agreement":null},{"id":"W1538899131","doi":"10.1023/a:1020427227285","title":"Camptothecin Delivery Methods","year":2002,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; University of Alberta","funders":"","keywords":"Camptothecin; Paclitaxel; Pharmacology; Chemistry; Pharmacokinetics; Medicine; Cancer; Internal medicine; Biochemistry","score_opus":0.5500320689040674,"score_gpt":0.6337683600768994,"score_spread":0.08373629117283199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1538899131","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00076558534,0.9831072,0.0057933326,0.0005594173,0.0009904308,0.000064680775,0.000064086795,0.00011154296,0.008543741],"genre_scores_gemma":[0.00293889,0.97867537,0.0045444095,0.0005287094,0.00027644122,0.00009315084,0.00012383334,0.000019633908,0.012799645],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999819,0.000016163223,0.000012921569,0.000040239796,0.00009209506,0.000019612153],"domain_scores_gemma":[0.99985325,0.0000684965,0.000019831567,0.000010697583,0.000034005538,0.000013750819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005852507,0.001285786,0.0013742023,0.0021962319,0.00049061904,0.0009215982,0.0012536305,0.001249297,0.0035483337],"category_scores_gemma":[0.00042586328,0.00044107717,0.00043159758,0.0016897838,0.0008721797,0.0013833506,0.00063166564,0.002342525,0.0036470767],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010316777,0.00013970798,0.000056955418,0.0049412427,0.00003292519,0.0004012827,0.0000513731,0.0004049348,0.027369034,0.0067951814,0.02591887,0.9337853],"study_design_scores_gemma":[0.000031151307,0.00008487206,0.00028993087,0.0005175013,0.000046922374,0.0016399781,0.000025104266,0.00019841042,0.015314483,0.0015723893,0.98025745,0.000021766413],"about_ca_topic_score_codex":0.0016760278,"about_ca_topic_score_gemma":0.0023736784,"teacher_disagreement_score":0.0035483337,"about_ca_system_score_codex":0.0012614068,"about_ca_system_score_gemma":0.0008219305,"threshold_uncertainty_score":0.011870325},"labels":[],"label_agreement":null},{"id":"W1548403504","doi":"10.1023/a:1011002913601","title":"Formulation and Evaluation of a Folic Acid Receptor-Targeted Oral Vancomycin Liposomal Dosage Form","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Dosage form; Vancomycin; Pharmacology; Folic acid; Liposome; Medicine; Chemistry; Internal medicine; Biochemistry; Biology; Staphylococcus aureus; Bacteria","score_opus":0.4739760453526366,"score_gpt":0.593581415675548,"score_spread":0.11960537032291141,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1548403504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98773324,0.0019402432,0.0091584725,0.00010469357,0.000040163148,0.00031254475,0.00013044318,0.00003603141,0.00054412277],"genre_scores_gemma":[0.990825,0.0011124699,0.0064837225,0.000030699706,0.00000967035,0.00007875788,0.00013832196,0.0000107865635,0.0013104682],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998429,0.000034318367,0.000015637022,0.000026037746,0.000060484574,0.00002070163],"domain_scores_gemma":[0.9999207,0.000011384422,0.000029193743,0.0000061308015,0.000019274808,0.000013292154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033146283,0.00017036358,0.00018583606,0.00015933947,0.00012705503,0.00027326588,0.00017879698,0.00024720412,0.00055224355],"category_scores_gemma":[0.00033425467,0.00009500192,0.00014768826,0.00008490799,0.00016083357,0.00017144579,0.00010521655,0.00022740451,0.00013431367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057453394,0.00013476875,0.000122007616,0.00008120007,0.000011302714,0.00007433862,0.000032475986,0.00039643806,0.98655474,0.00012119886,0.00005534069,0.011841714],"study_design_scores_gemma":[0.00016145576,0.0065562273,0.0011426201,0.000010635459,0.00006214495,0.00029260435,0.000027146712,0.0015969661,0.9868484,0.00002360066,0.0032694777,0.000008885175],"about_ca_topic_score_codex":0.00094563444,"about_ca_topic_score_gemma":0.00078994007,"teacher_disagreement_score":0.00094563444,"about_ca_system_score_codex":0.0002530613,"about_ca_system_score_gemma":0.00028517272,"threshold_uncertainty_score":0.0018802285},"labels":[],"label_agreement":null},{"id":"W1567936980","doi":"10.1023/a:1013090011952","title":"The Effect of Serum Albumin on Amphotericin B Aggregate Structure and Activity","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Lembaga Pengelola Dana Pendidikan","keywords":"Human serum albumin; Chemistry; Amphotericin B; Vesicle; Membrane; Biophysics; In vivo; Fluorescence spectroscopy; Ergosterol; Serum albumin; Albumin; Chromatography; Biochemistry; Fluorescence; Biology","score_opus":0.046217554197216126,"score_gpt":0.4415136102920808,"score_spread":0.3952960560948647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1567936980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967422,0.0011601571,0.001186835,0.00006368802,0.000019134943,0.0000100106445,0.0000793698,0.000030346107,0.0007083172],"genre_scores_gemma":[0.99845505,0.0002122858,0.0004485129,0.000034996425,0.0000063874813,0.0000047333338,0.00008561626,0.000013281826,0.00073906063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996773,0.00011170544,0.000030165258,0.000037402257,0.000062451196,0.00008099154],"domain_scores_gemma":[0.99950135,0.00025072735,0.00005722878,0.000044545297,0.00007085368,0.00007523377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003537956,0.00030369117,0.00023950024,0.0001905321,0.00017338601,0.0003671705,0.00021596033,0.00032825145,0.000811434],"category_scores_gemma":[0.00085549586,0.00014051388,0.00022323197,0.00016618038,0.00036143788,0.00027475707,0.00018718424,0.00035560946,0.00023972389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011195996,0.000048746184,0.0004740848,0.00003562866,0.000013745768,0.00007724187,0.000033828925,0.00010218073,0.99601495,0.000077688164,0.00003975703,0.0019625109],"study_design_scores_gemma":[0.000019155,0.0003102051,0.0032312975,0.0000020771338,0.0000123194295,0.00009429978,0.000011141751,0.00067568925,0.99521154,0.000027083766,0.00040066647,0.0000045236443],"about_ca_topic_score_codex":0.0020419864,"about_ca_topic_score_gemma":0.0010712066,"teacher_disagreement_score":0.0020419864,"about_ca_system_score_codex":0.00027237553,"about_ca_system_score_gemma":0.00024191065,"threshold_uncertainty_score":0.004060209},"labels":[],"label_agreement":null},{"id":"W1590254871","doi":"10.1023/a:1007516718048","title":"What is the True Solubility Advantage for Amorphous Pharmaceuticals?","year":2000,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1337,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"Merck Canada; University of Connecticut","keywords":"Solubility; Amorphous solid; Differential scanning calorimetry; Dissolution; Materials science; Supercooling; Thermodynamics; Glass transition; Hildebrand solubility parameter; Chemistry; Organic chemistry; Polymer; Physics","score_opus":0.4596834645305818,"score_gpt":0.6058326114622805,"score_spread":0.14614914693169873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1590254871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4025733,0.3310371,0.050621692,0.13959867,0.0042875996,0.000112636655,0.0010757099,0.00061006704,0.07008329],"genre_scores_gemma":[0.88223034,0.08615074,0.009715923,0.0092768045,0.0051072086,0.000073976335,0.0003393958,0.0001892947,0.0069163186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989266,0.0001773273,0.000057125435,0.0002179751,0.00047135187,0.00014959494],"domain_scores_gemma":[0.9972754,0.0015427419,0.00044894998,0.00019436929,0.00036659918,0.0001718886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016600997,0.00039788504,0.0013116035,0.00048219453,0.0005165664,0.002848594,0.00073491875,0.002092252,0.004148875],"category_scores_gemma":[0.0044328896,0.00036632316,0.00056926074,0.0003761913,0.0022355758,0.00677659,0.001095499,0.0017723461,0.0015755219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013311236,0.00035145183,0.0076412414,0.0054094135,0.0004313332,0.004287924,0.0006902171,0.002151871,0.4462733,0.16915038,0.02372428,0.3385575],"study_design_scores_gemma":[0.00026286294,0.001711229,0.013428042,0.000726373,0.00041174874,0.017637962,0.0020179828,0.0061282464,0.3498822,0.39499453,0.212556,0.00024280274],"about_ca_topic_score_codex":0.00045158024,"about_ca_topic_score_gemma":0.00038206638,"teacher_disagreement_score":0.004148875,"about_ca_system_score_codex":0.0006338363,"about_ca_system_score_gemma":0.0008163214,"threshold_uncertainty_score":0.013879359},"labels":[],"label_agreement":null},{"id":"W16624108","doi":"10.1023/a:1010965001162","title":"Fractal Volume of Drug Distribution: It Scales Proportionally to Body Mass","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Primate Behavior and Ecology","field":"Psychology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Fractal; Mass distribution; Distribution (mathematics); Volume (thermodynamics); Fractal dimension; Chemistry; Mathematics; Thermodynamics; Physics; Mathematical analysis","score_opus":0.181536110798459,"score_gpt":0.5318939198265168,"score_spread":0.3503578090280578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W16624108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87385166,0.003991997,0.11259,0.001178366,0.00010872489,0.000033437875,0.00028370577,0.0005063108,0.0074557527],"genre_scores_gemma":[0.9960517,0.00034084768,0.0030025218,0.00006778342,0.00008744096,0.000012293209,0.00006666085,0.00006882965,0.00030192937],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99968493,0.000116848125,0.000016934446,0.000073133895,0.00007833725,0.000029889463],"domain_scores_gemma":[0.99065334,0.0055869594,0.0019718579,0.0010153585,0.0003909027,0.0003816046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068642944,0.00030027606,0.00043270946,0.001243317,0.00026482853,0.0010411518,0.00035180096,0.0006909249,0.0011084704],"category_scores_gemma":[0.009215798,0.00033455595,0.00044413266,0.00042435434,0.0010940472,0.0015294884,0.00062907924,0.0006636961,0.00019452673],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014169841,0.00029360788,0.31643364,0.0007201219,0.0013830038,0.0007624889,0.0016984855,0.120179,0.18445627,0.1152089,0.0062905145,0.251157],"study_design_scores_gemma":[0.00006556104,0.0004873661,0.4344585,0.00007302684,0.000320504,0.0037832137,0.0002453247,0.3856147,0.015578562,0.1546851,0.0044863173,0.00020179054],"about_ca_topic_score_codex":0.00065466913,"about_ca_topic_score_gemma":0.0005207406,"teacher_disagreement_score":0.001243317,"about_ca_system_score_codex":0.00047677802,"about_ca_system_score_gemma":0.00022010147,"threshold_uncertainty_score":0.0037081838},"labels":[],"label_agreement":null},{"id":"W176733150","doi":"10.1023/a:1010984110732","title":"Effect of mdr1a P-Glycoprotein Gene Disruption, Gender, and Substrate Concentration on Brain Uptake of Selected Compounds","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; AstraZeneca (Canada)","funders":"","keywords":"Quinidine; Verapamil; P-glycoprotein; Chemistry; In vivo; Pharmacology; Efflux; Blood–brain barrier; Endocrinology; Internal medicine; Medicine; Biochemistry; Biology; Central nervous system; Calcium; Multiple drug resistance","score_opus":0.10744712860917593,"score_gpt":0.44518800220778043,"score_spread":0.3377408735986045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W176733150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99540436,0.0011896659,0.0006044204,0.00044632025,0.00014571018,0.000040532545,0.00074524106,0.000085058644,0.0013387545],"genre_scores_gemma":[0.99025846,0.00094490155,0.0010671382,0.00022470021,0.00009962486,0.00006497952,0.0008335388,0.00016274366,0.0063438877],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990978,0.0003070126,0.00008953376,0.00019561381,0.00008403767,0.0002259602],"domain_scores_gemma":[0.9969126,0.0017884456,0.00030083457,0.00017553699,0.00022084039,0.0006018421],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070629787,0.0008657174,0.0016564621,0.00060166675,0.00045927594,0.00093716144,0.00092181115,0.0009881058,0.0059042363],"category_scores_gemma":[0.0024090207,0.0007628258,0.0004350805,0.0005572336,0.0014012314,0.001387444,0.00049953145,0.001389186,0.0007952698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.07522157,0.0014593666,0.001788955,0.00011734295,0.00009220293,0.0010070687,0.0003645297,0.0005284385,0.9122214,0.00048862456,0.00078579865,0.005924662],"study_design_scores_gemma":[0.0007401481,0.012891183,0.012260319,0.000022099184,0.00031698294,0.0010343505,0.0004175988,0.003003668,0.96561015,0.000541521,0.0030307996,0.00013110945],"about_ca_topic_score_codex":0.0048193,"about_ca_topic_score_gemma":0.0057081473,"teacher_disagreement_score":0.0059042363,"about_ca_system_score_codex":0.0007849232,"about_ca_system_score_gemma":0.0011943835,"threshold_uncertainty_score":0.019751608},"labels":[],"label_agreement":null},{"id":"W1778681337","doi":"10.1007/s11095-015-1794-z","title":"Temperature/pH Responsive Hydrogels Based on Poly(ethylene glycol) and Functionalized Poly(e-caprolactone) Block Copolymers for Controlled Delivery of Macromolecules","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Hydrogels: synthesis, properties, applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Ethylene glycol; PEG ratio; Caprolactone; Self-healing hydrogels; Chemistry; Polymer chemistry; Copolymer; Polymer; Organic chemistry","score_opus":0.09234619024142945,"score_gpt":0.38319274407507153,"score_spread":0.2908465538336421,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1778681337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96794283,0.004807334,0.022756219,0.00020069804,0.00011590911,0.00009532797,0.00021985095,0.000257651,0.0036040908],"genre_scores_gemma":[0.9852201,0.0014318299,0.010233384,0.00008893677,0.00003153592,0.00005508949,0.00011316583,0.000034225974,0.0027917598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998845,0.000019402358,0.000009178145,0.000020833764,0.000030031706,0.00003607511],"domain_scores_gemma":[0.99989796,0.000022723885,0.000036740217,0.000006316445,0.000010900586,0.000025488212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024382354,0.00037505885,0.00013300743,0.00022044047,0.000106281506,0.00023935185,0.00023627319,0.00031365684,0.00094581273],"category_scores_gemma":[0.00017198297,0.00019449706,0.00020607814,0.00013935781,0.00021483385,0.0004980208,0.0002009553,0.00038018558,0.0002797097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062314415,0.000013368197,0.000020855265,0.00003428707,0.0000024049161,0.000029071623,0.000009700902,0.00015610244,0.9985348,0.00015172362,0.000023137813,0.0009622744],"study_design_scores_gemma":[0.000011338726,0.00007591453,0.00023487116,0.000003549179,0.000004740009,0.000049510974,0.0000037144066,0.00094086403,0.99795604,0.000032975597,0.0006815363,0.000004966341],"about_ca_topic_score_codex":0.00021877083,"about_ca_topic_score_gemma":0.00049140607,"teacher_disagreement_score":0.00094581273,"about_ca_system_score_codex":0.0003093439,"about_ca_system_score_gemma":0.00016107959,"threshold_uncertainty_score":0.003164053},"labels":[],"label_agreement":null},{"id":"W185249808","doi":"10.1023/a:1007561727948","title":"New Insights into the Pharmacokinetics and Metabolism of (R,S)-Ifosfamide in Cancer Patients Using a Population Pharmacokinetic-Metabolism Model","year":2000,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal","funders":"","keywords":"Ifosfamide; Pharmacokinetics; Metabolism; Population; Urine; Population pharmacokinetics; Pharmacology; Medicine; Chemistry; Internal medicine; Chemotherapy","score_opus":0.11877473751510755,"score_gpt":0.4605663561354775,"score_spread":0.34179161862036994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W185249808","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15836242,0.0037332654,0.82256836,0.003743458,0.00011109115,0.00015755977,0.0008420126,0.0004800346,0.010001818],"genre_scores_gemma":[0.9365219,0.0051701,0.04345975,0.0012301913,0.00024218291,0.00036751834,0.0006081627,0.00024565237,0.012154552],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99939454,0.00033719235,0.000022134534,0.00011328499,0.00006483448,0.00006795768],"domain_scores_gemma":[0.99913836,0.00057905505,0.00013421851,0.000051815725,0.00005897749,0.000037541435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019265172,0.0012348896,0.0022916463,0.0005414405,0.00029917902,0.0019199785,0.0011313296,0.0013558174,0.0025661124],"category_scores_gemma":[0.0043894867,0.00076240866,0.0023476612,0.0006372219,0.00065273256,0.0023765247,0.00059468986,0.0019583735,0.00061839505],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005919015,0.00024913438,0.009305548,0.000183897,0.00089405064,0.0010016798,0.00027867712,0.90010744,0.010659975,0.0450891,0.0021302786,0.029508287],"study_design_scores_gemma":[0.000112371985,0.00033201816,0.0024649543,0.00001892691,0.0004617901,0.0009525148,0.00004833414,0.9661397,0.0010655286,0.025395127,0.0029674354,0.00004135492],"about_ca_topic_score_codex":0.0064016706,"about_ca_topic_score_gemma":0.004062072,"teacher_disagreement_score":0.0064016706,"about_ca_system_score_codex":0.0011921562,"about_ca_system_score_gemma":0.0017567221,"threshold_uncertainty_score":0.01272881},"labels":[],"label_agreement":null},{"id":"W1890421635","doi":"10.1007/s11095-015-1762-7","title":"Assessment of Age-Related Changes in Pediatric Gastrointestinal Solubility","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Solubility; Biopharmaceutical; Chemistry; Medicine; Chromatography; Organic chemistry; Biology","score_opus":0.5284577599816123,"score_gpt":0.5924248725826259,"score_spread":0.06396711260101362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1890421635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99423766,0.00218758,0.0017262796,0.00003016971,0.000012879616,0.000030347755,0.0005907126,0.000042649295,0.0011416374],"genre_scores_gemma":[0.99639314,0.001086159,0.001480917,0.000020731735,0.000009986336,0.000029718145,0.00040103315,0.000012529567,0.0005657529],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99966145,0.00005980487,0.000040697585,0.000078632256,0.000120228724,0.00003911584],"domain_scores_gemma":[0.9984402,0.0002811336,0.00072019844,0.00008779613,0.00035469446,0.00011600922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063558243,0.00030233458,0.00033741797,0.00076625595,0.00013865225,0.00040479316,0.00013635698,0.00027370834,0.00072978635],"category_scores_gemma":[0.001793697,0.00011704339,0.00032220664,0.00059483387,0.00020366919,0.00042165868,0.00031141762,0.0003806273,0.0002247534],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039350465,0.00015520657,0.83055514,0.00022821789,0.00016560366,0.0010669699,0.00054772786,0.0006684388,0.1088949,0.00027525023,0.00027595987,0.053231526],"study_design_scores_gemma":[0.000008576366,0.001884837,0.9282702,0.000013862499,0.00013800668,0.0021350964,0.00026312485,0.0009772155,0.06388292,0.00006863891,0.0023434055,0.000014036129],"about_ca_topic_score_codex":0.0013675941,"about_ca_topic_score_gemma":0.00091217033,"teacher_disagreement_score":0.0013675941,"about_ca_system_score_codex":0.00031526524,"about_ca_system_score_gemma":0.00029169527,"threshold_uncertainty_score":0.0033612847},"labels":[],"label_agreement":null},{"id":"W196242335","doi":"10.1023/a:1007548905772","title":"Route-Dependent Metabolism of Morphine in the Vascularly Perfused Rat Small Intestine Preparation","year":2000,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Glucuronidation; Metabolism; Verapamil; Chemistry; Pharmacology; Small intestine; Metabolite; Glucuronide; Duodenum; Lumen (anatomy); First pass effect; Efflux; Pharmacokinetics; Bolus (digestion); Drug metabolism; Endocrinology; Internal medicine; Microsome; Biochemistry; Biology; In vitro; Medicine; Calcium","score_opus":0.14294986504742785,"score_gpt":0.4512733704099056,"score_spread":0.30832350536247777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W196242335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98980254,0.0024575167,0.0045476356,0.00012612887,0.00013756272,0.00015101783,0.00048983307,0.000075107986,0.002212589],"genre_scores_gemma":[0.97805744,0.002660308,0.010157819,0.00011373829,0.00012268382,0.0001510269,0.0011259201,0.00008794799,0.0075231614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979395,0.000033271725,0.000011985877,0.000055442324,0.000028540624,0.00007678452],"domain_scores_gemma":[0.99976355,0.000049901457,0.000059608028,0.000051211806,0.000036453854,0.000039225404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003472493,0.00069965154,0.00063579687,0.0003826372,0.00049004296,0.0004064332,0.00051875005,0.00043597704,0.0026148516],"category_scores_gemma":[0.00039818388,0.00035538033,0.00057405775,0.0003493235,0.00062214956,0.0007311894,0.00028914487,0.00092574593,0.00045918202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010562133,0.00010738964,0.00061507546,0.00013684366,0.000042473166,0.00023570417,0.000117192554,0.00020467829,0.98304594,0.00050057383,0.00007846161,0.0043536075],"study_design_scores_gemma":[0.0001112594,0.0025511056,0.003612634,0.000013770242,0.00013015122,0.00020785873,0.00007246923,0.000800214,0.990607,0.00008625604,0.0017928114,0.0000144633295],"about_ca_topic_score_codex":0.002128347,"about_ca_topic_score_gemma":0.0032935275,"teacher_disagreement_score":0.0026148516,"about_ca_system_score_codex":0.00049368,"about_ca_system_score_gemma":0.0009229682,"threshold_uncertainty_score":0.008747578},"labels":[],"label_agreement":null},{"id":"W1964959608","doi":"10.1007/s11095-005-6306-0","title":"Potential Role of Acyl-Coenzyme A:Cholesterol Transferase (ACAT) Inhibitors as Hypolipidemic and Antiatherosclerosis Drugs","year":2005,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Sterol O-acyltransferase; Cholesteryl ester; Cholesterol; Very low-density lipoprotein; Endocrinology; Reverse cholesterol transport; Biochemistry; Intermediate-density lipoprotein; Chemistry; Coenzyme A; Endoplasmic reticulum; Internal medicine; Acyl-CoA; Apolipoprotein B; Apolipoprotein E; Biology; Lipoprotein; Enzyme; Reductase; Medicine","score_opus":0.14897846755962332,"score_gpt":0.4942521781279735,"score_spread":0.3452737105683502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964959608","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036689133,0.997729,0.00017822164,0.00020490232,0.00017936235,0.0000075398716,0.00002512301,0.0000079423635,0.0013009796],"genre_scores_gemma":[0.0011806431,0.99703896,0.00040615915,0.000241065,0.00017345998,0.000009173049,0.00005408681,0.00000164636,0.0008949061],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99985397,0.000022794358,0.000023995412,0.000024450766,0.000057647652,0.000017130264],"domain_scores_gemma":[0.9997483,0.00011214718,0.00004662839,0.00000734134,0.000058445235,0.000027176993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007064504,0.0009807602,0.0016850156,0.0024105774,0.00024557638,0.0009938243,0.0009993155,0.0010349975,0.003907384],"category_scores_gemma":[0.00054866093,0.00027056763,0.00058176136,0.0024034875,0.00037373469,0.0011440351,0.0004582917,0.0015235395,0.0020145779],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038123014,0.00026663436,0.00023603377,0.012424041,0.00019478182,0.0006044271,0.00004815169,0.00040694553,0.0049796617,0.002572495,0.020740185,0.9571453],"study_design_scores_gemma":[0.00018493844,0.0003371855,0.0012670942,0.0019311125,0.00042371967,0.0016664496,0.000053023912,0.00019244516,0.0017214707,0.0012669105,0.99093294,0.000022801125],"about_ca_topic_score_codex":0.0009126146,"about_ca_topic_score_gemma":0.0023678218,"teacher_disagreement_score":0.003907384,"about_ca_system_score_codex":0.00049578137,"about_ca_system_score_gemma":0.00078195526,"threshold_uncertainty_score":0.013071477},"labels":[],"label_agreement":null},{"id":"W1965442455","doi":"10.1007/s11095-009-9897-z","title":"Nanoparticulate Systems for Growth Factor Delivery","year":2009,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":192,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Drug delivery; Growth factor; Nanotechnology; Medicine; Pharmacology; Materials science","score_opus":0.33639715474570653,"score_gpt":0.500264822819458,"score_spread":0.16386766807375153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965442455","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008751762,0.988955,0.0038985908,0.00032289443,0.0008241632,0.00003766192,0.00003703078,0.000044499233,0.005005052],"genre_scores_gemma":[0.0037742425,0.9828196,0.004174269,0.0003152054,0.00034099485,0.00005141854,0.000079783174,0.000013629937,0.008430823],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998286,0.00001738197,0.000015876833,0.000034578065,0.00008292173,0.000020593132],"domain_scores_gemma":[0.999892,0.000039866743,0.000020197358,0.0000057115813,0.000031694522,0.000010533697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060245435,0.001593422,0.0015312079,0.0021725667,0.0003498741,0.00084042276,0.0010109465,0.0012276892,0.0026282168],"category_scores_gemma":[0.00044575648,0.0005141885,0.00047466691,0.001682643,0.0005723177,0.0015175577,0.0008521301,0.0017430078,0.0028403534],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010332974,0.00017979997,0.00006188133,0.0084965,0.000071680835,0.00045424947,0.00006266464,0.0010177298,0.04989902,0.0070291464,0.020070484,0.9125535],"study_design_scores_gemma":[0.00003456486,0.00011723535,0.00020671959,0.00095544185,0.00008190898,0.0014431223,0.00002801228,0.00045659725,0.017495142,0.0015883523,0.9775645,0.000028350698],"about_ca_topic_score_codex":0.0010964292,"about_ca_topic_score_gemma":0.0024461756,"teacher_disagreement_score":0.0026282168,"about_ca_system_score_codex":0.00083396037,"about_ca_system_score_gemma":0.0008281024,"threshold_uncertainty_score":0.008792222},"labels":[],"label_agreement":null},{"id":"W1965546738","doi":"10.1023/b:pham.0000041444.06122.8d","title":"Peroxisome Proliferator-Activated Receptor (PPAR)-α: A Pharmacological Target with a Promising Future","year":2004,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":270,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"U.S. Department of Veterans Affairs","keywords":"Peroxisome proliferator-activated receptor; Internal medicine; PPAR agonist; Insulin resistance; Dyslipidemia; Endocrinology; Nuclear receptor; Peroxisome proliferator-activated receptor alpha; Metabolic syndrome; Receptor; Lipid metabolism; Biology; Medicine; Diabetes mellitus; Transcription factor; Biochemistry","score_opus":0.1271914017369632,"score_gpt":0.4588999292057641,"score_spread":0.3317085274688009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965546738","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015629901,0.99556196,0.00046957904,0.0007634154,0.00078857667,0.000006610222,0.000021853577,0.000021106463,0.0022105637],"genre_scores_gemma":[0.0006872785,0.99515826,0.00063694944,0.00062172714,0.0004084917,0.0000094157285,0.000043105283,0.0000029391113,0.0024317608],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998154,0.000026881804,0.000019901105,0.000040088238,0.0000746484,0.000023182096],"domain_scores_gemma":[0.9996679,0.00013129324,0.000031587097,0.00001319216,0.0001060805,0.000050027185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008137073,0.0013949389,0.0020263493,0.0015900288,0.00044332832,0.0013513415,0.0012389614,0.0019860684,0.005286923],"category_scores_gemma":[0.0006521334,0.00031210124,0.0004219478,0.002343498,0.00081552874,0.002108259,0.00053614605,0.002651957,0.0061887363],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024105601,0.00015153331,0.0001292191,0.007314156,0.00005758477,0.00038694518,0.000039481634,0.0003781215,0.005161107,0.004078149,0.059288383,0.9227744],"study_design_scores_gemma":[0.000048632122,0.00011005093,0.00031442335,0.0007993364,0.000069043104,0.0011221193,0.00005511467,0.00007389126,0.0007944225,0.0015912439,0.9950063,0.000015288306],"about_ca_topic_score_codex":0.0013794367,"about_ca_topic_score_gemma":0.0029536842,"teacher_disagreement_score":0.005286923,"about_ca_system_score_codex":0.000990732,"about_ca_system_score_gemma":0.0012271053,"threshold_uncertainty_score":0.017686546},"labels":[],"label_agreement":null},{"id":"W1966334833","doi":"10.1007/s11095-004-1873-z","title":"A Scalable, Extrusion-Free Method for Efficient Liposomal Encapsulation of Plasmid DNA","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":307,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Innovative Targeting Solutions (Canada)","funders":"","keywords":"Liposome; Chromatography; Chemistry; Dilution; Vesicle; Dispersity; Extrusion; Population; DNA; Aqueous solution; Solubility; Biophysics; Biochemistry; Materials science; Biology; Organic chemistry","score_opus":0.1072674820972407,"score_gpt":0.46585078369332855,"score_spread":0.35858330159608787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966334833","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38253677,0.007979633,0.59978986,0.0009033537,0.00043703872,0.0009805885,0.0013916758,0.0021623815,0.0038186854],"genre_scores_gemma":[0.6041794,0.005759898,0.37338814,0.00032177908,0.00009209435,0.0007820492,0.0026407517,0.00036654764,0.012469321],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995927,0.00004304453,0.000043996606,0.00008493438,0.00019704395,0.000038214053],"domain_scores_gemma":[0.9998394,0.00003871597,0.000046708974,0.000030896455,0.000023137773,0.00002113907],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044447486,0.0005953319,0.00064339454,0.00036930628,0.0003340607,0.0004927802,0.00072015007,0.0008505033,0.0010409688],"category_scores_gemma":[0.00036685998,0.00043044816,0.00046100604,0.00029531476,0.0003260846,0.00079235487,0.00072014966,0.0015803446,0.0009888955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025456437,0.000018741028,0.000025256477,0.000060338618,0.0000040529735,0.000048482794,0.000011850926,0.00007536101,0.99548966,0.0001715903,0.000112142036,0.0039570257],"study_design_scores_gemma":[0.000021271582,0.00007226915,0.00024030333,0.000005560137,0.00000923241,0.00024358598,0.000005588893,0.0009089183,0.99459225,0.000057636284,0.0038267968,0.000016561238],"about_ca_topic_score_codex":0.00024703494,"about_ca_topic_score_gemma":0.0005472549,"teacher_disagreement_score":0.0010409688,"about_ca_system_score_codex":0.0003409747,"about_ca_system_score_gemma":0.0003886457,"threshold_uncertainty_score":0.0034824014},"labels":[],"label_agreement":null},{"id":"W1966747907","doi":"10.1007/s11095-012-0858-6","title":"Inhibition of Cholesterol Absorption: Targeting the Intestine","year":2012,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Cholesterol; Medicine; Coronary artery disease; Cholesterol lowering; Gastrointestinal tract; Pharmacology; Internal medicine; Bioinformatics; Biology","score_opus":0.39239691532684723,"score_gpt":0.5312233324568828,"score_spread":0.13882641713003557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966747907","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015141277,0.998719,0.00016125706,0.00020889699,0.00017084622,0.000007202339,0.000017256041,0.000009276925,0.0005549369],"genre_scores_gemma":[0.0006747887,0.99837863,0.00023975266,0.00017369752,0.00011009911,0.0000065057143,0.000025115549,0.0000013057246,0.00039007305],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998078,0.000027258715,0.000027736685,0.000036142734,0.00007158909,0.000029411869],"domain_scores_gemma":[0.99972755,0.000117268515,0.00005315678,0.000009041664,0.000058723876,0.00003420199],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075550965,0.0016376823,0.0026995144,0.0024962658,0.00027639524,0.001171722,0.0010961165,0.001500847,0.0030643477],"category_scores_gemma":[0.00064429967,0.00043787254,0.00093520444,0.0022286642,0.00064012234,0.0013734997,0.0007485011,0.0026873222,0.0020956935],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025444786,0.00023893091,0.00014992194,0.02287694,0.00024793475,0.0002265851,0.000034434983,0.00036602493,0.0046199644,0.0021441325,0.022261564,0.94657904],"study_design_scores_gemma":[0.0002103284,0.00041525572,0.0014055398,0.0052508037,0.0006625347,0.0015814223,0.000070225,0.00023247863,0.0019287644,0.001881805,0.98631245,0.000048467748],"about_ca_topic_score_codex":0.0010029351,"about_ca_topic_score_gemma":0.0024149271,"teacher_disagreement_score":0.0030643477,"about_ca_system_score_codex":0.0005440131,"about_ca_system_score_gemma":0.00096488395,"threshold_uncertainty_score":0.010251224},"labels":[],"label_agreement":null},{"id":"W1968320351","doi":"10.1007/s11095-011-0476-8","title":"Novel Therapies Targeting Inner Mitochondrial Membrane—From Discovery to Clinical Development","year":2011,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Mitochondrion; Oxidative stress; Inner mitochondrial membrane; Bioinformatics; Medicine; Mitochondrial disease; Biology; Pharmacology; Function (biology); Neuroscience; Computational biology; Mitochondrial DNA; Cell biology; Internal medicine; Genetics; Gene","score_opus":0.3789190490416239,"score_gpt":0.5186634443280874,"score_spread":0.13974439528646354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968320351","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001231466,0.99732214,0.0005147621,0.0005947718,0.0004111543,0.000008083351,0.000021467184,0.000019671837,0.0009848585],"genre_scores_gemma":[0.001004304,0.99642545,0.00070968695,0.00065334263,0.0003408735,0.000015843934,0.00004427036,0.000003751704,0.0008024489],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99976784,0.00003504735,0.000028010565,0.000048241884,0.00009009006,0.000030716623],"domain_scores_gemma":[0.99950004,0.0002629657,0.000054551845,0.000018645203,0.000110283756,0.000053386328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011245427,0.0015840131,0.002347795,0.0021305662,0.0003639929,0.0014273789,0.001364718,0.0020009293,0.0027830284],"category_scores_gemma":[0.0010932492,0.00043495191,0.00058061746,0.0017474255,0.0010580966,0.002004283,0.000870316,0.0040648603,0.0020356071],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018353805,0.00018080132,0.000118534655,0.007145136,0.000097743214,0.00031152111,0.00003212672,0.00049242604,0.004186372,0.0059777154,0.046460036,0.93481404],"study_design_scores_gemma":[0.00011284699,0.00020014103,0.0004916872,0.0018929873,0.00014067518,0.001388886,0.000044348697,0.00022449282,0.0017438126,0.0043861796,0.9893426,0.000031397773],"about_ca_topic_score_codex":0.0008729991,"about_ca_topic_score_gemma":0.0023553788,"teacher_disagreement_score":0.0027830284,"about_ca_system_score_codex":0.0011078311,"about_ca_system_score_gemma":0.001269891,"threshold_uncertainty_score":0.009310186},"labels":[],"label_agreement":null},{"id":"W1970655806","doi":"10.1007/s11095-008-9615-2","title":"Solid Lipid Nanoparticles Enhance the Delivery of the HIV Protease Inhibitor, Atazanavir, by a Human Brain Endothelial Cell Line","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":197,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Ontario HIV Treatment Network","keywords":"Atazanavir; Solid lipid nanoparticle; Drug delivery; Protease inhibitor (pharmacology); Lentivirus; Ritonavir; Pharmacology; Cell culture; Protease; Brain Cell; Delivery system; Chemistry; Virology; Human immunodeficiency virus (HIV); Nanoparticle; Medicine; Nanotechnology; Biochemistry; Materials science; Biology; Cell biology; Enzyme; Antiretroviral therapy; Viral disease","score_opus":0.08956744807904041,"score_gpt":0.4100729558429092,"score_spread":0.32050550776386877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970655806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99441385,0.0009181999,0.0024760955,0.000106190266,0.00002461797,0.000019109335,0.00010864901,0.000034858764,0.001898317],"genre_scores_gemma":[0.99283606,0.00068892445,0.002945259,0.00003694513,0.000009023641,0.000012300987,0.00017985617,0.000012345011,0.0032793237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990535,0.000018473997,0.000007051678,0.000014040075,0.0000310742,0.000024014733],"domain_scores_gemma":[0.9999479,0.000020365856,0.0000073253836,0.000005412398,0.000013096248,0.0000059660165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014661781,0.00020413949,0.00020048449,0.00015328298,0.00013934438,0.00038349992,0.00015272756,0.00032031324,0.0008440909],"category_scores_gemma":[0.00012825133,0.00011839342,0.00018989187,0.00011730652,0.00010931078,0.00020470785,0.00013213657,0.00033164455,0.00027999893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001312347,0.00006160733,0.00007134468,0.000027044052,0.0000066340194,0.000055695393,0.000021735876,0.00013671104,0.9970396,0.00015886988,0.00007136223,0.0022180777],"study_design_scores_gemma":[0.00001986629,0.00018739975,0.00044970622,0.0000021626943,0.000014651808,0.00006669365,0.000013050978,0.0011195958,0.99681735,0.000026720652,0.00128043,0.0000024075641],"about_ca_topic_score_codex":0.002056652,"about_ca_topic_score_gemma":0.0026409305,"teacher_disagreement_score":0.002056652,"about_ca_system_score_codex":0.00032207213,"about_ca_system_score_gemma":0.00027255347,"threshold_uncertainty_score":0.0040893555},"labels":[],"label_agreement":null},{"id":"W1971430341","doi":"10.1023/b:pham.0000045232.18134.e9","title":"The Arthrotropism of Macromolecules in Adjuvant-Induced Arthritis Rat Model: A Preliminary Study","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; McGill University; University of Utah","keywords":"Methacrylamide; Biodistribution; Macromolecule; Magnetic resonance imaging; Arthritis; Medicine; Pathology; Rheumatoid arthritis; Evans Blue; Chemistry; Biophysics; Polymer; Internal medicine; Radiology; Biochemistry; Biology; Copolymer; In vitro","score_opus":0.12660256442817372,"score_gpt":0.45615458980790197,"score_spread":0.3295520253797283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971430341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98752815,0.0058926614,0.003396326,0.00025259313,0.00008699607,0.000120790384,0.00024379372,0.00006126709,0.002417467],"genre_scores_gemma":[0.9839557,0.007019199,0.0025555901,0.00010778662,0.00011378587,0.000070434224,0.00032624192,0.000015327947,0.0058358125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985254,0.00002209026,0.000009685038,0.000020823049,0.00003361334,0.00006123392],"domain_scores_gemma":[0.9997416,0.00004462362,0.00005817686,0.000031313866,0.000044476958,0.000079775455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039160607,0.000891444,0.00042644865,0.0008402322,0.00036142117,0.0002451969,0.00034020597,0.0005089379,0.0018100861],"category_scores_gemma":[0.0002099053,0.00024294894,0.0006282871,0.00035929997,0.0005255495,0.00054845883,0.00019839122,0.0008620589,0.00044326347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010815468,0.0006332923,0.0003625434,0.00011132405,0.0000117681975,0.0002581112,0.00004719357,0.00007561914,0.99455255,0.00016998657,0.000058216843,0.0026379016],"study_design_scores_gemma":[0.00013187173,0.014192658,0.0053234827,0.000020495669,0.00013283783,0.00055946317,0.000120995224,0.0005605569,0.97662145,0.00021095522,0.0021079867,0.000017241742],"about_ca_topic_score_codex":0.0019998546,"about_ca_topic_score_gemma":0.0021601778,"teacher_disagreement_score":0.0019998546,"about_ca_system_score_codex":0.00020997036,"about_ca_system_score_gemma":0.00046293178,"threshold_uncertainty_score":0.0060552955},"labels":[],"label_agreement":null},{"id":"W1971492925","doi":"10.1007/s11095-005-9646-x","title":"Report on the PQRI Impurity Characterization and Quantification Best Practices Survey","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced NMR Techniques and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Eli Lilly (Canada)","funders":"","keywords":"Characterization (materials science); Chemistry; Chromatography; Nanotechnology; Materials science","score_opus":0.4144008310124296,"score_gpt":0.5557081731414133,"score_spread":0.14130734212898372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971492925","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5439239,0.062141877,0.2383576,0.015453812,0.0015918062,0.0021943778,0.015565164,0.0070245666,0.113746926],"genre_scores_gemma":[0.6907207,0.024234252,0.19356182,0.009108808,0.0009585458,0.00064016326,0.022458496,0.0013260613,0.056991216],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9934726,0.0011264394,0.0007733589,0.0007427595,0.0034639088,0.0004210773],"domain_scores_gemma":[0.9729707,0.006100403,0.0025015597,0.0020867623,0.01568481,0.00065574184],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0093891565,0.00068362674,0.000810336,0.004946284,0.0014346213,0.0025399667,0.001203353,0.0012776454,0.0047843317],"category_scores_gemma":[0.010348477,0.00026298998,0.00088595226,0.003868114,0.0005481643,0.001349435,0.0010299222,0.0009185436,0.0034274873],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086781994,0.00097388466,0.059964467,0.0012813675,0.00039557958,0.000982304,0.0008297981,0.0023809967,0.16067193,0.0021708172,0.030952014,0.73852897],"study_design_scores_gemma":[0.000048274,0.0016857375,0.06591487,0.00021463266,0.00070001703,0.002161052,0.0016731389,0.002931337,0.63598025,0.0014231898,0.28710285,0.0001646721],"about_ca_topic_score_codex":0.0069078477,"about_ca_topic_score_gemma":0.007135911,"teacher_disagreement_score":0.0093891565,"about_ca_system_score_codex":0.0014981591,"about_ca_system_score_gemma":0.0023923046,"threshold_uncertainty_score":0.0496552},"labels":[],"label_agreement":null},{"id":"W1972203426","doi":"10.1007/s11095-007-9244-1","title":"Expression of the ATP-binding Cassette Membrane Transporter, ABCG2, in Human and Rodent Brain Microvessel Endothelial and Glial Cell Culture Systems","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Toronto","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Multiple Sclerosis Society; Ontario HIV Treatment Network","keywords":"Abcg2; Microvessel; Biology; Cell culture; Molecular biology; Western blot; ATP-binding cassette transporter; Blood–brain barrier; Endothelial stem cell; Human brain; Cell biology; Transporter; Angiogenesis; Biochemistry; Cancer research; In vitro; Endocrinology; Central nervous system","score_opus":0.06949907511749769,"score_gpt":0.4098027177208796,"score_spread":0.3403036426033819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972203426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98289317,0.0033123356,0.010132069,0.00019808194,0.00006363694,0.00006206831,0.001080755,0.000090576934,0.002167276],"genre_scores_gemma":[0.9790592,0.0025877028,0.011344472,0.000086716165,0.000029104645,0.00011684124,0.0032307473,0.000043835527,0.0035014036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963534,0.000085330634,0.000048413563,0.000056264827,0.00008914984,0.00008554883],"domain_scores_gemma":[0.99982625,0.000045756602,0.000024485955,0.000031431115,0.00004844332,0.000023778612],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005309081,0.00016550864,0.0003355839,0.00034897085,0.00029137646,0.00055104634,0.00024887396,0.00029504063,0.0009730448],"category_scores_gemma":[0.00041857595,0.00018774175,0.00028877708,0.00050900975,0.00021312945,0.00033816893,0.00018292232,0.00053404423,0.0003345196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030483303,0.000055993067,0.00045505224,0.00007829655,0.000023938062,0.00013510986,0.00016851825,0.0001513954,0.9956727,0.00079246995,0.00023201312,0.0019297125],"study_design_scores_gemma":[0.00006486701,0.0007170834,0.007486882,0.000020028454,0.00016469043,0.0012579478,0.00020905088,0.003265992,0.97544426,0.00020642333,0.011142684,0.000020159108],"about_ca_topic_score_codex":0.0034366143,"about_ca_topic_score_gemma":0.0040266467,"teacher_disagreement_score":0.0034366143,"about_ca_system_score_codex":0.0004046286,"about_ca_system_score_gemma":0.0003039093,"threshold_uncertainty_score":0.0068332553},"labels":[],"label_agreement":null},{"id":"W1976209099","doi":"10.1007/s11095-013-1259-1","title":"Current Challenges in Bioequivalence, Quality, and Novel Assessment Technologies for Topical Products","year":2014,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"FSD Pharma (Canada)","funders":"American Association of Pharmaceutical Scientists","keywords":"Bioequivalence; Pharmaceutical industry; Risk analysis (engineering); Quality (philosophy); Quality by Design; Management science; Regulatory science; Product (mathematics); Computer science; Medicine; New product development; Business; Pharmacology; Engineering; Bioavailability; Marketing","score_opus":0.7074066587856508,"score_gpt":0.6422555944921446,"score_spread":0.06515106429350614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976209099","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00033836724,0.9965239,0.0010893777,0.0007543959,0.00013383232,0.0000071017816,0.000024400704,0.000011338014,0.0011172054],"genre_scores_gemma":[0.0024509614,0.9944484,0.0014564253,0.0005038671,0.00023148928,0.000011662407,0.000043719618,0.000004613792,0.0008488568],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990319,0.00016180014,0.00010215942,0.00017083556,0.00046885226,0.00006437077],"domain_scores_gemma":[0.9977278,0.0014563894,0.00023667267,0.00006424279,0.0004423534,0.00007256532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0032412072,0.00085663784,0.0020531223,0.0018216781,0.0003481383,0.0021838653,0.0014353935,0.0021870066,0.0033261883],"category_scores_gemma":[0.002223975,0.00039822084,0.0007806341,0.0022042592,0.001234056,0.0029089996,0.001016201,0.0025333224,0.0012356179],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097398806,0.00010715483,0.0002528531,0.012539074,0.00006266777,0.00017639252,0.000063542684,0.00060431554,0.0067517003,0.009348672,0.011227996,0.9587682],"study_design_scores_gemma":[0.000024799516,0.00024225116,0.0010298232,0.0035135478,0.00017929211,0.0014423704,0.00019009979,0.0004779997,0.0047126426,0.008221699,0.97991633,0.00004918445],"about_ca_topic_score_codex":0.0016506622,"about_ca_topic_score_gemma":0.0025038978,"teacher_disagreement_score":0.0033261883,"about_ca_system_score_codex":0.0010094162,"about_ca_system_score_gemma":0.002167757,"threshold_uncertainty_score":0.017141342},"labels":[],"label_agreement":null},{"id":"W1977310114","doi":"10.1007/s11095-007-9471-5","title":"Novel Lipid and Preservative-free Propofol Formulation: Properties and Pharmacodynamics","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Armand Frappier Museum; Micropharma (Canada)","funders":"","keywords":"Propofol; Pharmacodynamics; Micelle; Candida albicans; Preservative; Pharmacology; Chemistry; Pharmacokinetics; Righting reflex; Medicine; Anesthesia; Microbiology; Biology; Food science; Reflex; Organic chemistry","score_opus":0.26911516271085656,"score_gpt":0.45994907003796337,"score_spread":0.1908339073271068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977310114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874105,0.0036997267,0.0076370058,0.0002218802,0.000056053144,0.000070190625,0.00007787746,0.000030999923,0.0007958709],"genre_scores_gemma":[0.99099964,0.0020702686,0.0053575863,0.000107370775,0.000039470244,0.000030440264,0.00011801317,0.000010656788,0.0012665971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993765,0.000016803318,0.0000050704357,0.000009735315,0.000020183008,0.000010526866],"domain_scores_gemma":[0.99985886,0.0000343002,0.00004751441,0.0000073363153,0.00002108918,0.00003084409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000187326,0.00020164992,0.0002071439,0.00013742145,0.00012697715,0.0002382569,0.00020013003,0.0001830394,0.000944971],"category_scores_gemma":[0.00032753497,0.00008071409,0.00014106443,0.00008245823,0.00015552626,0.00032738136,0.00014544396,0.00044142627,0.00014407524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031379682,0.00036761147,0.0005322688,0.00018970846,0.000029147806,0.00030786556,0.00007407011,0.00034129192,0.94287723,0.0004143679,0.00023071415,0.05149779],"study_design_scores_gemma":[0.0005504102,0.014342516,0.0047041564,0.000024643923,0.00014326534,0.0021448883,0.000070265756,0.00289075,0.96823263,0.00020743944,0.0066613713,0.000027583228],"about_ca_topic_score_codex":0.00020554946,"about_ca_topic_score_gemma":0.00024400353,"teacher_disagreement_score":0.000944971,"about_ca_system_score_codex":0.00011151912,"about_ca_system_score_gemma":0.00026987563,"threshold_uncertainty_score":0.0031612515},"labels":[],"label_agreement":null},{"id":"W1978190051","doi":"10.1007/s11095-008-9597-0","title":"Use of Tc-99m Mebrofenin as a Clinical Probe to Assess Altered Hepatobiliary Transport: Integration of In Vitro, Pharmacokinetic Modeling, and Simulation Studies","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Multidrug resistance-associated protein 2; Pharmacokinetics; Chemistry; Pharmacology; Excretion; Efflux; Urine; Physiologically based pharmacokinetic modelling; Glucuronide; In vitro; Transporter; Hepatocyte; Internal medicine; ATP-binding cassette transporter; Medicine; Biochemistry","score_opus":0.6639344229145775,"score_gpt":0.5853236702177169,"score_spread":0.07861075269686058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978190051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90522444,0.0036878753,0.087663144,0.00042717234,0.00004605285,0.00015892061,0.00018004148,0.000326292,0.0022860703],"genre_scores_gemma":[0.9848342,0.0009185788,0.0136612775,0.000060564133,0.00000631121,0.000036473317,0.0000610459,0.000051195137,0.00037031947],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9996505,0.0001964725,0.00001128852,0.000034898392,0.00008278996,0.000024023017],"domain_scores_gemma":[0.99958235,0.0002527671,0.0000721002,0.000040317038,0.00003258121,0.00001995172],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009688483,0.00044538756,0.00089670776,0.00034324027,0.00023496349,0.00091733306,0.00040262143,0.0006274392,0.00047490653],"category_scores_gemma":[0.001331573,0.0002781996,0.00026838636,0.00035341398,0.0003809442,0.0006066415,0.00018346924,0.0005840189,0.00017472201],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035116486,0.0004856237,0.010585598,0.00017892923,0.00012795364,0.00037449616,0.0001445725,0.03493729,0.9002733,0.0010198319,0.00036382285,0.047996946],"study_design_scores_gemma":[0.00023894379,0.004255074,0.0120969545,0.000021786775,0.00024070441,0.0015412731,0.00011490842,0.3275756,0.6503674,0.0004378249,0.0030393535,0.000070184185],"about_ca_topic_score_codex":0.0031449685,"about_ca_topic_score_gemma":0.0024616038,"teacher_disagreement_score":0.0031449685,"about_ca_system_score_codex":0.0005529889,"about_ca_system_score_gemma":0.00060712505,"threshold_uncertainty_score":0.0062533617},"labels":[],"label_agreement":null},{"id":"W1978862031","doi":"10.1007/s11095-006-9217-9","title":"The Evolving Role of Drug Metabolism in Drug Discovery and Development","year":2007,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"ADME; Drug metabolism; Drug discovery; Pharmacology; Pharmacogenomics; Drug; Computational biology; Drug development; Pharmacogenetics; Biology; Bioinformatics; Genetics","score_opus":0.3889439312688324,"score_gpt":0.5860510311367881,"score_spread":0.19710709986795572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978862031","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015368148,0.99653167,0.0010807002,0.0008516147,0.00030309637,0.0000036468884,0.000010751623,0.000013596888,0.001051262],"genre_scores_gemma":[0.0008432314,0.99664813,0.0009947426,0.0004820061,0.00055545603,0.000005103219,0.000013179153,0.0000026753787,0.00045547218],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992873,0.00022115186,0.00007380377,0.000109918656,0.00026562985,0.000042193926],"domain_scores_gemma":[0.9978229,0.0014987702,0.0001744168,0.00006511609,0.0003376753,0.0001012149],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022023586,0.0011555766,0.002783494,0.0018886486,0.00035624413,0.0020817788,0.0013340903,0.002198785,0.0027297644],"category_scores_gemma":[0.0017914412,0.00045257914,0.00061535486,0.0035134528,0.0015484057,0.0029206893,0.0010528408,0.0031371657,0.0020379808],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007662228,0.00006264658,0.0002588721,0.007427754,0.000067368856,0.00021968578,0.00004549107,0.0005339584,0.0021415886,0.009487557,0.0146778375,0.9650007],"study_design_scores_gemma":[0.00003226045,0.00016364986,0.000912384,0.0020277018,0.00013317294,0.0017352463,0.000090545036,0.0004388792,0.0013209861,0.011846129,0.9812633,0.000035698853],"about_ca_topic_score_codex":0.0013591794,"about_ca_topic_score_gemma":0.0022990075,"teacher_disagreement_score":0.002783494,"about_ca_system_score_codex":0.0013055631,"about_ca_system_score_gemma":0.0019717568,"threshold_uncertainty_score":0.011647344},"labels":[],"label_agreement":null},{"id":"W1979836228","doi":"10.1023/b:pham.0000041458.81836.c4","title":"Tamoxifen Alters Hepatic Cytochrome P450 Enzyme Expression and Circulating Growth Hormone Levels in Intact Male Rats","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Medical Research Council Canada","keywords":"Endocrinology; Internal medicine; Tamoxifen; Triiodothyronine; Testosterone (patch); Cytochrome P450; Hormone; Biology; Medicine; Chemistry; Metabolism; Cancer; Breast cancer","score_opus":0.3261665139244788,"score_gpt":0.5312953775401043,"score_spread":0.20512886361562543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979836228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956536,0.0004850468,0.0016342681,0.00021962202,0.00008184439,0.000019944331,0.0009557056,0.00018975513,0.0007600894],"genre_scores_gemma":[0.98022985,0.0009899619,0.002499054,0.00018728906,0.00005637468,0.00011826443,0.0015242547,0.00017644856,0.014218488],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995378,0.000042751628,0.000027324872,0.0001475582,0.0000933761,0.00015117071],"domain_scores_gemma":[0.999215,0.00010019802,0.00027874167,0.00010786998,0.00006509876,0.00023298514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001837702,0.00073860376,0.0006383872,0.0014583777,0.00038194313,0.00052972935,0.0004320269,0.0006561242,0.0038125955],"category_scores_gemma":[0.00035377083,0.00053302915,0.00045357793,0.00046174842,0.00113361,0.0008580883,0.0002722556,0.0014173607,0.0010389275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041145473,0.00036295276,0.0009052232,0.000017723527,0.000016109363,0.00011941343,0.000059830032,0.000057763067,0.9916013,0.00012566707,0.000118001066,0.0025014663],"study_design_scores_gemma":[0.00020456943,0.0030785545,0.015746618,0.000009477289,0.000120821154,0.00026639973,0.00026267208,0.0008205963,0.97771865,0.00020253677,0.0015371868,0.000031849944],"about_ca_topic_score_codex":0.0028348297,"about_ca_topic_score_gemma":0.0053114216,"teacher_disagreement_score":0.0038125955,"about_ca_system_score_codex":0.00080289075,"about_ca_system_score_gemma":0.00045588982,"threshold_uncertainty_score":0.012754381},"labels":[],"label_agreement":null},{"id":"W1982381743","doi":"10.1007/s11095-014-1598-6","title":"Dependence of PEI and PAMAM Gene Delivery on Clathrin- and Caveolin-Dependent Trafficking Pathways","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health; McMaster University","keywords":"Endocytic cycle; Endocytosis; Polyethylenimine; Clathrin; Gene delivery; Internalization; Cell biology; Transfection; Endosome; Caveolin; Biology; Receptor-mediated endocytosis; Pinocytosis; Caveolae; Signal transduction; Intracellular; Biochemistry; Cell; Gene","score_opus":0.10924413406032413,"score_gpt":0.3926725932667632,"score_spread":0.28342845920643905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982381743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98971164,0.001755118,0.003182427,0.0001344082,0.000029486113,0.000030724692,0.0003128812,0.00008879309,0.0047544995],"genre_scores_gemma":[0.9924339,0.0007296461,0.0025576279,0.0000568233,0.0000102931435,0.000041677533,0.0004428177,0.000034291734,0.0036929147],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997414,0.000059297927,0.000024533332,0.00003306009,0.00008226407,0.00005946555],"domain_scores_gemma":[0.99948704,0.00028010993,0.000065644286,0.00005486391,0.0000612263,0.000051094037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028671738,0.00022639961,0.00017750057,0.00018737048,0.00016185464,0.00033472056,0.00021741149,0.00024249301,0.0013547383],"category_scores_gemma":[0.0005224177,0.00015274897,0.00018173493,0.00016662305,0.0002885712,0.0004135993,0.00027442747,0.0003908352,0.0003267705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028520063,0.0000149399375,0.0000913677,0.00003534144,0.0000037367836,0.000043235133,0.000015842552,0.000045839144,0.99780864,0.00042818277,0.000027488633,0.0012003061],"study_design_scores_gemma":[0.000004716033,0.000054645538,0.0017700631,0.0000028879022,0.000003626067,0.00007822418,0.0000075874145,0.00034912012,0.9970489,0.000042780983,0.00063491066,0.0000024300236],"about_ca_topic_score_codex":0.00086249976,"about_ca_topic_score_gemma":0.0014194578,"teacher_disagreement_score":0.0013547383,"about_ca_system_score_codex":0.00054209994,"about_ca_system_score_gemma":0.0004002715,"threshold_uncertainty_score":0.0045319796},"labels":[],"label_agreement":null},{"id":"W1984661805","doi":"10.1007/s11095-012-0913-3","title":"Efficacy of Mucoadhesive Hydrogel Microparticles of Whey Protein and Alginate for Oral Insulin Delivery","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Pharmaceutical technology; Self-healing hydrogels; Drug delivery; Dosage form; Chemistry; Whey protein; Microparticle; Drug carrier; Mucoadhesion; Pharmacology; Insulin; Delivery system; Medicine; Chromatography; Chemical engineering; Internal medicine","score_opus":0.3924213221588325,"score_gpt":0.5619529662274786,"score_spread":0.16953164406864607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984661805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99682754,0.0018332624,0.00080207246,0.000035507026,0.000033316373,0.000015488456,0.000051610663,0.000018173945,0.00038304421],"genre_scores_gemma":[0.9982127,0.0004983151,0.0005996922,0.000018338194,0.000013202852,0.00000943388,0.000046728426,0.000006765251,0.00059480575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998555,0.000023785977,0.000016936463,0.000023831864,0.00003949618,0.00004041996],"domain_scores_gemma":[0.999828,0.00006196585,0.000045914225,0.000011560807,0.000022100336,0.000030493198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003249144,0.00021475542,0.00018368225,0.00013832806,0.00013840922,0.00022253896,0.00015277097,0.00029621032,0.00060939556],"category_scores_gemma":[0.00036239016,0.0001270898,0.00031579167,0.0000845928,0.0001811811,0.0003238802,0.00014547142,0.00030265612,0.00009224487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007904715,0.000084002524,0.00015719922,0.00006693096,0.000013538534,0.00003774937,0.000027871827,0.00007987945,0.9955961,0.000050061895,0.000028922446,0.0030673256],"study_design_scores_gemma":[0.000037591806,0.0007977562,0.0010700889,0.0000029756384,0.000026600712,0.000044053424,0.000006819455,0.00042898057,0.99726486,0.000007197609,0.0003094594,0.0000035920755],"about_ca_topic_score_codex":0.00075652654,"about_ca_topic_score_gemma":0.0006234477,"teacher_disagreement_score":0.00075652654,"about_ca_system_score_codex":0.00022896686,"about_ca_system_score_gemma":0.00018167551,"threshold_uncertainty_score":0.0020386577},"labels":[],"label_agreement":null},{"id":"W1984814708","doi":"10.1023/b:pham.0000048189.79606.6e","title":"Effects of Pluronic P85 on GLUT1 and MCT1 Transporters in the Blood-Brain Barrier","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Supratek Pharma (Canada)","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"GLUT1; Microvessel; Blood–brain barrier; Glucose transporter; Glucose Transporter Type 1; Transporter; Chemistry; Pharmacology; Efflux; P-glycoprotein; Monocarboxylate transporter; Biochemistry; Biophysics; Biology; Central nervous system; Angiogenesis; Endocrinology; Insulin; Cancer research","score_opus":0.06201603594588193,"score_gpt":0.4187153881181335,"score_spread":0.35669935217225157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984814708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971227,0.0015871171,0.00031217557,0.00009276466,0.000015475205,0.000005740895,0.000035787405,0.000009812644,0.00081856136],"genre_scores_gemma":[0.99760085,0.0009415469,0.000354426,0.000042566444,0.0000131211755,0.000005925943,0.00007378286,0.000005359063,0.00096243067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998467,0.00004603873,0.00001010205,0.000012238038,0.000027174976,0.000057735317],"domain_scores_gemma":[0.9998348,0.00007890274,0.000030513595,0.000012163309,0.000017356004,0.000026256794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023848486,0.00023973486,0.00025104074,0.00015275653,0.00020765825,0.00029053207,0.00016176299,0.00032268927,0.0011273002],"category_scores_gemma":[0.00038311552,0.00011317263,0.0002083089,0.00017362325,0.00034008114,0.0006095544,0.0001737912,0.0005735554,0.00014629897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0048016994,0.00018008114,0.00035703296,0.00020293133,0.000029491255,0.00021060546,0.00013388379,0.0004145589,0.982372,0.0010106801,0.00022134838,0.010065792],"study_design_scores_gemma":[0.0001204969,0.001987691,0.0034867353,0.000011805189,0.000056185076,0.00020643756,0.00010249609,0.0017444219,0.99044365,0.00016560948,0.0016643042,0.000010070423],"about_ca_topic_score_codex":0.0023210857,"about_ca_topic_score_gemma":0.0019085265,"teacher_disagreement_score":0.0023210857,"about_ca_system_score_codex":0.00034838266,"about_ca_system_score_gemma":0.00033753444,"threshold_uncertainty_score":0.004615128},"labels":[],"label_agreement":null},{"id":"W1986186085","doi":"10.1023/b:pham.0000029284.40637.69","title":"A Novel One-Step Drug-Loading Procedure for Water-Soluble Amphiphilic Nanocarriers","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":109,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Micropharma (Canada); Université de Montréal; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Nanocarriers; Micelle; Amphiphile; Solubility; Partition coefficient; Solubilization; Chemistry; Dispersity; Drug; Dissolution; Drug carrier; Drug delivery; Nanotechnology; Copolymer; Chromatography; Materials science; Aqueous solution; Organic chemistry; Polymer; Pharmacology; Biochemistry","score_opus":0.15646147797199006,"score_gpt":0.4202338141857662,"score_spread":0.26377233621377616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986186085","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.37086675,0.006153345,0.608562,0.0008055629,0.00042161308,0.0017372294,0.0008179093,0.002834976,0.007800717],"genre_scores_gemma":[0.6404813,0.004540016,0.33667994,0.0005777787,0.00017249986,0.0012328333,0.0009344002,0.00052014744,0.014861138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963224,0.00004341564,0.000044579097,0.00010475034,0.00012986013,0.000045152872],"domain_scores_gemma":[0.9997367,0.00007150834,0.00007399084,0.000039837636,0.00004662127,0.000031343112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041900855,0.0008911378,0.000686753,0.0006147824,0.00051327795,0.00034083173,0.00063794473,0.0006426086,0.0016822162],"category_scores_gemma":[0.00042740404,0.0004941028,0.00038801582,0.0003376044,0.0004293912,0.0010376786,0.0005718839,0.0013874474,0.0012774805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030567102,0.000041329684,0.000026426287,0.00009454453,0.000005770835,0.000041448417,0.00002669891,0.000059878083,0.9915651,0.00024144011,0.00013131628,0.007735443],"study_design_scores_gemma":[0.000008696505,0.000064795444,0.00021021914,0.0000029792461,0.000008361313,0.00012818714,0.000003890683,0.00036838287,0.99670815,0.00004139267,0.002441036,0.00001391801],"about_ca_topic_score_codex":0.0005952388,"about_ca_topic_score_gemma":0.0011946213,"teacher_disagreement_score":0.0016822162,"about_ca_system_score_codex":0.0003958215,"about_ca_system_score_gemma":0.00062538986,"threshold_uncertainty_score":0.0056275725},"labels":[],"label_agreement":null},{"id":"W1989638710","doi":"10.1023/b:pham.0000012164.60867.c6","title":"Study of the Micellization Behavior of Different Order Amino Block Copolymers with Heparin","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Dispersity; Copolymer; Polymer chemistry; Atom-transfer radical-polymerization; Dynamic light scattering; Gel permeation chromatography; Polyelectrolyte; Polymer; Ionic strength; Chemistry; Ethylene glycol; Static light scattering; Polymerization; Materials science; Organic chemistry; Aqueous solution; Nanoparticle; Nanotechnology","score_opus":0.29099229439468655,"score_gpt":0.5373723818171231,"score_spread":0.24638008742243656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989638710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980513,0.0003436202,0.0008920219,0.000020059893,0.0000072336647,0.00001032774,0.000034387343,0.000010141679,0.00063096575],"genre_scores_gemma":[0.9976095,0.00028885505,0.0006558721,0.000018361474,0.000005571136,0.000007728489,0.000048252277,0.000008699656,0.0013571181],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987876,0.00001823813,0.000006095402,0.000021907474,0.000032574648,0.000042454045],"domain_scores_gemma":[0.9998287,0.00005463821,0.000053845117,0.00000970775,0.000032051874,0.00002104563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018933647,0.00020641382,0.00010541822,0.00011454803,0.00010830713,0.00015593864,0.00011100329,0.00016661861,0.0009533047],"category_scores_gemma":[0.00033265437,0.00009463789,0.00017125692,0.00015508747,0.00014600047,0.00024073261,0.00008733453,0.00028227322,0.00018196033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106178755,0.00001325621,0.00014969849,0.000014753281,0.0000030918804,0.0000199094,0.000017496393,0.00010230644,0.9988757,0.0000698082,0.000011728994,0.00061603374],"study_design_scores_gemma":[0.000004456765,0.00016348307,0.0012826526,0.0000014286863,0.000006953907,0.000028599057,0.000007180205,0.0011580221,0.99707127,0.000008239356,0.0002651346,0.0000025807997],"about_ca_topic_score_codex":0.0012956976,"about_ca_topic_score_gemma":0.0008788405,"teacher_disagreement_score":0.0012956976,"about_ca_system_score_codex":0.00023720699,"about_ca_system_score_gemma":0.00020730672,"threshold_uncertainty_score":0.0031891465},"labels":[],"label_agreement":null},{"id":"W1989897941","doi":"10.1023/b:pham.0000036906.65263.da","title":"The Role of Metabolites in Bioequivalence","year":2004,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"U.S. Food and Drug Administration","keywords":"Bioequivalence; Context (archaeology); Metabolite; Drug; Pharmacology; Medicine; Pharmacokinetics; Biology; Internal medicine","score_opus":0.9374920013793809,"score_gpt":0.7844228098714564,"score_spread":0.15306919150792453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989897941","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009624751,0.9957911,0.0032561559,0.00041793645,0.00010710749,0.000005247296,0.00000962471,0.000006128986,0.00031056872],"genre_scores_gemma":[0.0026319905,0.9931443,0.0033981837,0.00021610121,0.00040095818,0.000019837988,0.000013957115,0.000005016584,0.00016963242],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959628,0.0024793008,0.00045497518,0.00026478173,0.0007857114,0.000052420713],"domain_scores_gemma":[0.972735,0.024954472,0.0009808686,0.00042298142,0.0008084102,0.00009818217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008242395,0.00140365,0.004546507,0.003874303,0.00024616125,0.0021475009,0.0013935725,0.0021912272,0.0023728248],"category_scores_gemma":[0.017874762,0.00058894634,0.0013563675,0.005300258,0.0025436939,0.002641085,0.0009626614,0.0029434368,0.0007317652],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017605866,0.00006228641,0.00027221497,0.030035524,0.00054917164,0.00011779081,0.00007316379,0.003974951,0.00045373966,0.034307316,0.0068049133,0.9231729],"study_design_scores_gemma":[0.00035763308,0.0007376838,0.0029199952,0.030083176,0.0021004626,0.003435423,0.00019319223,0.0076565733,0.0029656673,0.22923394,0.7201204,0.00019588828],"about_ca_topic_score_codex":0.0016246577,"about_ca_topic_score_gemma":0.0018250515,"teacher_disagreement_score":0.008242395,"about_ca_system_score_codex":0.0011961408,"about_ca_system_score_gemma":0.0026979886,"threshold_uncertainty_score":0.043590486},"labels":[],"label_agreement":null},{"id":"W1991310381","doi":"10.1007/s11095-007-9262-z","title":"Influence of Mouthpiece Geometry on the Aerosol Delivery Performance of a Dry Powder Inhaler","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Australian Research Council; University of Alberta","keywords":"Mouthpiece; Inhaler; Dry-powder inhaler; Throat; Materials science; Metered-dose inhaler; Geometry; Medicine; Biomedical engineering; Mathematics; Surgery; Dentistry; Asthma; Internal medicine","score_opus":0.13444633472435943,"score_gpt":0.4385514416235356,"score_spread":0.30410510689917614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991310381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966673,0.0011409166,0.0015424667,0.00004922552,0.00003574289,0.00002156184,0.000092643015,0.000048807706,0.0004012981],"genre_scores_gemma":[0.99718505,0.00050938677,0.0017355069,0.000043516648,0.000018667666,0.0000121760695,0.000091580856,0.00003490008,0.00036922295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995763,0.00011711889,0.00004549613,0.000081784,0.00011664371,0.00006266579],"domain_scores_gemma":[0.998672,0.00086317095,0.00014978606,0.00006873301,0.00017735364,0.00006892212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057641254,0.00033253228,0.00052511436,0.00016074418,0.00021475952,0.0005405193,0.0002974002,0.00054109126,0.0014636039],"category_scores_gemma":[0.0022975225,0.0003043529,0.0003132023,0.0001246138,0.00022479799,0.0004398247,0.00028104332,0.00021474295,0.00045405744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002171952,0.000052327843,0.0012371256,0.00011921973,0.000022858643,0.00013177418,0.0000791378,0.0008167583,0.9879452,0.000027492622,0.00007409415,0.00732215],"study_design_scores_gemma":[0.000119147386,0.0046218755,0.016087668,0.000014599697,0.00016125485,0.00040399865,0.00012218421,0.0048978105,0.97261703,0.000033825778,0.0008798579,0.000040627492],"about_ca_topic_score_codex":0.00044449282,"about_ca_topic_score_gemma":0.00032096833,"teacher_disagreement_score":0.0014636039,"about_ca_system_score_codex":0.0001649193,"about_ca_system_score_gemma":0.00020746372,"threshold_uncertainty_score":0.0048962235},"labels":[],"label_agreement":null},{"id":"W1991790115","doi":"10.1007/s11095-010-0340-2","title":"The Role of the Transition Metal Copper and the Ionophore A23187 in the Development of Irinophore C™","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development; BC Cancer Agency; University of British Columbia","funders":"Canadian Institutes of Health Research; British Columbia Innovation Council","keywords":"Ionophore; Copper; Chemistry; Calcium","score_opus":0.03909682609417519,"score_gpt":0.38602842627998196,"score_spread":0.34693160018580677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991790115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96761435,0.013780095,0.0059553403,0.0010131104,0.00013919565,0.00005411176,0.00012395935,0.00020677643,0.0111129545],"genre_scores_gemma":[0.9868689,0.005174789,0.0034067174,0.000106933214,0.000034127035,0.00003260772,0.000116566895,0.00003127867,0.004228061],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998565,0.000043189462,0.000009795448,0.00001693916,0.000030171614,0.00004350554],"domain_scores_gemma":[0.99975055,0.00009023038,0.00004610372,0.000026604981,0.000023717772,0.00006281363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004263326,0.00023791753,0.00018232244,0.0002083204,0.00022561417,0.00050553994,0.00032630976,0.00038985407,0.0007739769],"category_scores_gemma":[0.00042243156,0.00018871341,0.00013627678,0.00008439885,0.00032918094,0.0005211532,0.00026371537,0.00050757296,0.0003439901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005821805,0.00006653905,0.00043651584,0.00011791678,0.000011496022,0.00054996397,0.000047036425,0.00020653753,0.98368084,0.0026355481,0.00040657574,0.011258793],"study_design_scores_gemma":[0.00003217439,0.0002288007,0.0018092567,0.000010485079,0.000018364824,0.0005426658,0.00005569452,0.0008154267,0.98903966,0.00029694126,0.00714083,0.000009735511],"about_ca_topic_score_codex":0.00047477553,"about_ca_topic_score_gemma":0.0004378264,"teacher_disagreement_score":0.0007739769,"about_ca_system_score_codex":0.0004637027,"about_ca_system_score_gemma":0.00038410054,"threshold_uncertainty_score":0.0033644438},"labels":[],"label_agreement":null},{"id":"W1991909351","doi":"10.1007/s11095-007-9412-3","title":"Predicting the Solubility of the Anti-Cancer Agent Docetaxel in Small Molecule Excipients using Computational Methods","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":108,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; BioPhage Pharma (Canada); University of Toronto","funders":"","keywords":"Docetaxel; Solubility; Chemistry; Excipient; Molecular dynamics; Chromatography; Computational chemistry; Organic chemistry; Cancer; Medicine","score_opus":0.6327525557782577,"score_gpt":0.6484099683070088,"score_spread":0.01565741252875108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991909351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9453482,0.00047233154,0.048578307,0.00046017388,0.000033711793,0.00005389205,0.00047135414,0.00029999609,0.004282009],"genre_scores_gemma":[0.98441964,0.00020172987,0.013947232,0.00003870447,0.000010036357,0.00006140174,0.00024051334,0.000031882642,0.0010487393],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99991345,0.000027037066,0.000006279101,0.000012890589,0.000027979668,0.000012294845],"domain_scores_gemma":[0.99916804,0.0006711337,0.000050996303,0.000021505852,0.00006390382,0.000024354174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000400407,0.00040210306,0.0006600416,0.00046558597,0.00036922196,0.0007425326,0.00048772042,0.00093915575,0.0009867445],"category_scores_gemma":[0.001466013,0.0004496113,0.00073351274,0.0004198202,0.00031627313,0.00063613756,0.00025585832,0.00051171525,0.00015704434],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036428777,0.000024266867,0.00079395965,0.00002605345,0.000014131512,0.000030882784,0.000005869542,0.99571437,0.0007694452,0.0004813024,0.00010282037,0.0020005226],"study_design_scores_gemma":[0.0000069777616,0.000009088731,0.00006778359,8.228821e-7,0.000003728457,0.0000031601205,0.0000021856847,0.99924636,0.00044835007,0.00016244009,0.000047869198,0.0000012327057],"about_ca_topic_score_codex":0.01301505,"about_ca_topic_score_gemma":0.008873624,"teacher_disagreement_score":0.01301505,"about_ca_system_score_codex":0.00079801213,"about_ca_system_score_gemma":0.0015421456,"threshold_uncertainty_score":0.025878608},"labels":[],"label_agreement":null},{"id":"W1992203674","doi":"10.1007/s11095-011-0530-6","title":"Development of Novel Peptides for Mitochondrial Drug Delivery: Amino Acids Featuring Delocalized Lipophilic Cations","year":2011,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Lipophilicity; Peptide; Amino acid; Mitochondrion; Chemistry; Drug delivery; Biochemistry; Oligopeptide; Biophysics; Combinatorial chemistry; Biology; Organic chemistry","score_opus":0.23513268940507298,"score_gpt":0.42221774984760063,"score_spread":0.18708506044252765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992203674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.963594,0.005428244,0.027681623,0.00039735626,0.00013947712,0.00025196644,0.0001817914,0.00014005441,0.0021855347],"genre_scores_gemma":[0.9656466,0.0039495393,0.027281193,0.00025152884,0.000044892084,0.00013660644,0.00022598478,0.00003121177,0.002432308],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999149,0.000015817568,0.000008111619,0.000019283778,0.000017657994,0.00002425882],"domain_scores_gemma":[0.99981993,0.000028831408,0.000058421057,0.000009635757,0.000026697391,0.000056472523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033702154,0.0004883524,0.00032841298,0.00014581335,0.00016236721,0.00036278943,0.00030231697,0.0005899545,0.0008368833],"category_scores_gemma":[0.0002556486,0.00018222356,0.0002195804,0.0001032499,0.00026048676,0.0006056395,0.0003231335,0.0007175352,0.0003644592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021250483,0.000055426637,0.00007759894,0.000117414646,0.000010050389,0.00017708923,0.000028017714,0.0005664175,0.99191815,0.0005716864,0.0000728903,0.0061927126],"study_design_scores_gemma":[0.000105211344,0.00081509823,0.00030641834,0.000014011532,0.000022970355,0.00039876715,0.0000142531535,0.0011385122,0.99158305,0.00013031873,0.0054577333,0.000013783099],"about_ca_topic_score_codex":0.00016982658,"about_ca_topic_score_gemma":0.000203964,"teacher_disagreement_score":0.0008368833,"about_ca_system_score_codex":0.00027598048,"about_ca_system_score_gemma":0.00020644,"threshold_uncertainty_score":0.0027996302},"labels":[],"label_agreement":null},{"id":"W1992588670","doi":"10.1007/s11095-010-0068-z","title":"In Vivo Distribution of Polymeric Nanoparticles at the Whole-Body, Tumor, and Cellular Levels","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":131,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"In vivo; Biodistribution; Chemistry; Cancer research; Biophysics; Biology","score_opus":0.0800358320636464,"score_gpt":0.3950557673408315,"score_spread":0.3150199352771851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992588670","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98449415,0.0035657235,0.007677886,0.00022864294,0.000090946065,0.000032358523,0.00037878694,0.00018749596,0.0033439912],"genre_scores_gemma":[0.9893367,0.0013077757,0.0019350349,0.00008109867,0.000028851584,0.000042714688,0.00037086874,0.00007044987,0.006826357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985015,0.00002775567,0.000005581296,0.000047911006,0.000026746158,0.000041812764],"domain_scores_gemma":[0.9998498,0.000048515107,0.00003253778,0.000019859868,0.000019952224,0.000029349163],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030183632,0.00044542196,0.00035409658,0.00033281837,0.00018068287,0.00042705258,0.0002166062,0.0005619373,0.001361173],"category_scores_gemma":[0.00022739888,0.00027802723,0.00030515977,0.00015165615,0.00041274758,0.0006000372,0.00013275744,0.0008853222,0.00035757912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002290854,0.00017182052,0.00022912143,0.00004121003,0.000016648166,0.000047352096,0.00003709665,0.00045981994,0.9915867,0.00021193521,0.00012484578,0.0047826455],"study_design_scores_gemma":[0.000057586727,0.0020998032,0.0025313757,0.000004637638,0.000051767616,0.00020156446,0.000026187981,0.0020864985,0.99142635,0.00014786865,0.001355643,0.0000107684355],"about_ca_topic_score_codex":0.0008901746,"about_ca_topic_score_gemma":0.0006968334,"teacher_disagreement_score":0.001361173,"about_ca_system_score_codex":0.00038384742,"about_ca_system_score_gemma":0.00030972576,"threshold_uncertainty_score":0.0045535564},"labels":[],"label_agreement":null},{"id":"W1992908365","doi":"10.1007/s11095-014-1524-y","title":"Vitamin D Receptor Activation Induces P-Glycoprotein and Increases Brain Efflux of Quinidine:An Intracerebral Microdialysis Study in Conscious Rats","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Pfizer Canada; National Institutes of Health; National Institute for Health and Care Research","keywords":"Microdialysis; Quinidine; Calcitriol receptor; P-glycoprotein; Internal medicine; Endocrinology; Pharmacology; Chemistry; Efflux; Blood–brain barrier; CYP3A; Extracellular; Receptor; Pregnane X receptor; Pharmacokinetics; Cytochrome P450; Medicine; Metabolism; Central nervous system; Biochemistry","score_opus":0.11311493018620507,"score_gpt":0.46960871675476773,"score_spread":0.3564937865685627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992908365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964155,0.00068172,0.0018708222,0.00018409072,0.000044819022,0.000034758865,0.0002770638,0.00006172138,0.00042951177],"genre_scores_gemma":[0.9932474,0.0010741637,0.0024905032,0.00009180062,0.000053002695,0.00009196114,0.00036253425,0.00003235636,0.0025562593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99964345,0.00004653714,0.000024049163,0.00009525772,0.000071022,0.00011969458],"domain_scores_gemma":[0.99954116,0.000078865654,0.00011671083,0.00009486334,0.0000459116,0.00012263835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027668578,0.00069877924,0.00077516196,0.0005199757,0.00052741554,0.0005131774,0.0005589257,0.00063462544,0.0012305739],"category_scores_gemma":[0.00033898882,0.00051530276,0.00073291396,0.00034283247,0.0012409129,0.0010248594,0.00029288183,0.0018535145,0.00025706206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010256435,0.0005148598,0.00068257103,0.00005410264,0.000060611386,0.00024921392,0.0001391491,0.0000696237,0.98537505,0.00027070468,0.00013977899,0.0021880155],"study_design_scores_gemma":[0.0003247791,0.004096353,0.009961151,0.0000046707787,0.00018409913,0.00031423266,0.00020215787,0.0010439489,0.9830428,0.00019091158,0.00060184614,0.000033095093],"about_ca_topic_score_codex":0.0065353694,"about_ca_topic_score_gemma":0.009749211,"teacher_disagreement_score":0.0065353694,"about_ca_system_score_codex":0.0008983065,"about_ca_system_score_gemma":0.00074380497,"threshold_uncertainty_score":0.012994707},"labels":[],"label_agreement":null},{"id":"W1993273579","doi":"10.1007/s11095-011-0402-0","title":"O-Linked Glycosylation Leads to Decreased Thermal Stability of Interferon Alpha 2b as Measured by Two Orthogonal Techniques","year":2011,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Biotechnology Research Institute; University of Ottawa; Health Canada","funders":"Government of Canada","keywords":"Glycosylation; Thermal stability; Alpha (finance); Chemistry; Alpha interferon; Stability (learning theory); Thermal; Pharmaceutical technology; Materials science; Thermodynamics; Chromatography; Interferon; Medicine; Biochemistry; Physics; Organic chemistry; Immunology; Computer science; Surgery","score_opus":0.21079186801990554,"score_gpt":0.44617732884814787,"score_spread":0.23538546082824233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993273579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99414873,0.00043754972,0.004593474,0.00005479131,0.00002125946,0.000014786058,0.00009638008,0.000022156235,0.00061088457],"genre_scores_gemma":[0.9928226,0.00044672153,0.005044031,0.00009159122,0.000012791097,0.000042934164,0.00038991828,0.000033484706,0.0011159882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99956113,0.00013829833,0.000039100014,0.000075599404,0.00008464552,0.00010131563],"domain_scores_gemma":[0.99941504,0.00013506769,0.00027155282,0.000069198,0.000054046275,0.000055118762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046182066,0.0005833116,0.00020349566,0.00019322091,0.00023705844,0.0004024906,0.00023381147,0.00039632688,0.0007465798],"category_scores_gemma":[0.00049187586,0.0002797433,0.0003736246,0.0002756421,0.00052328466,0.00023201536,0.00028446424,0.0008494471,0.00022344576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019840675,0.000014736501,0.00015666062,0.0000076874985,0.0000045205875,0.000007807248,0.00001599321,0.000030807318,0.9991574,0.000031465464,0.000007909492,0.0003664938],"study_design_scores_gemma":[0.000011778192,0.0001570851,0.0024425588,0.000002896084,0.00001160144,0.000063189465,0.000014405024,0.00029156104,0.99671006,0.000024152605,0.00026507696,0.000005506305],"about_ca_topic_score_codex":0.00038238047,"about_ca_topic_score_gemma":0.0006053789,"teacher_disagreement_score":0.0007465798,"about_ca_system_score_codex":0.0003151925,"about_ca_system_score_gemma":0.00021990787,"threshold_uncertainty_score":0.0024975538},"labels":[],"label_agreement":null},{"id":"W1994498234","doi":"10.1007/pl00022054","title":"A Parenteral Econazole Formulation Using a Novel Micelle-to-Liposome Transfer Method: In Vitro Characterization and Tumor Growth Delay in a Breast Cancer Xenograft Model","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University Health Network; University of Toronto; BC Cancer Agency","funders":"Canadian Breast Cancer Research Alliance; Breast Cancer Alliance; Cancer Research Institute","keywords":"Econazole; Liposome; Pharmacology; Micelle; Chemistry; Pharmacokinetics; Drug; Prodrug; Dosage form; Medicine; Biochemistry; Miconazole; Organic chemistry","score_opus":0.10130592593586835,"score_gpt":0.41519142681115273,"score_spread":0.3138855008752844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994498234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97759557,0.0017216381,0.01915313,0.00017002154,0.000050386454,0.000075476746,0.00011993614,0.0000998879,0.0010139527],"genre_scores_gemma":[0.9863261,0.00072291115,0.010144454,0.000041118572,0.000012131824,0.00002555673,0.00009984474,0.000026887355,0.0026009905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999366,0.000009256171,0.000004934977,0.000018915605,0.000018370862,0.000011955972],"domain_scores_gemma":[0.9999474,0.000013094506,0.000016324095,0.0000051022816,0.000009385552,0.000008603645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014423935,0.00020055429,0.00014736065,0.00015333574,0.0001134063,0.00015449192,0.00016554935,0.00026951538,0.00060860266],"category_scores_gemma":[0.00016826644,0.000097440534,0.00012485917,0.00011626661,0.00017044433,0.00024528807,0.00008850238,0.00034689956,0.00013847508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015563928,0.000029057384,0.00006320864,0.000017126535,0.0000020822408,0.000032457738,0.0000064044625,0.000038543083,0.9971124,0.00003978922,0.000032361862,0.0024708696],"study_design_scores_gemma":[0.000018371074,0.00043389347,0.0005606665,0.0000011799818,0.00000757364,0.00011684501,0.0000032092823,0.0004363775,0.9978143,0.0000060941334,0.0005979672,0.0000034327725],"about_ca_topic_score_codex":0.0012514204,"about_ca_topic_score_gemma":0.0017693983,"teacher_disagreement_score":0.0012514204,"about_ca_system_score_codex":0.00023142126,"about_ca_system_score_gemma":0.00028004887,"threshold_uncertainty_score":0.0024882555},"labels":[],"label_agreement":null},{"id":"W2000191937","doi":"10.1007/s11095-010-0357-6","title":"Magnetic Resonance Imaging and Image Analysis for Assessment of HPMC Matrix Tablets Structural Evolution in USP Apparatus 4","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Council Canada","keywords":"Materials science; Dissolution; Magnetic resonance imaging; Matrix (chemical analysis); Biomedical engineering; Nuclear magnetic resonance; Chemistry; Composite material; Medicine; Physics; Radiology","score_opus":0.17469602432415476,"score_gpt":0.5580098892151886,"score_spread":0.3833138648910338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000191937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.67627823,0.0035556185,0.31506017,0.00012367898,0.000060338847,0.00040378305,0.0005092974,0.001061827,0.002947114],"genre_scores_gemma":[0.65747696,0.0025484953,0.33479756,0.0000896626,0.000041569332,0.0005156047,0.0007471841,0.00014167262,0.003641309],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999653,0.00007660833,0.000025113213,0.000058139813,0.00016296915,0.00002407661],"domain_scores_gemma":[0.99963117,0.00012888997,0.00007423853,0.000033853717,0.000104643295,0.0000272591],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006575741,0.00041617046,0.00018445714,0.00083683437,0.00021560153,0.00024147604,0.00021308493,0.00041321685,0.0022586025],"category_scores_gemma":[0.00080741814,0.00022249506,0.00018864505,0.0003690717,0.00026208485,0.00033488494,0.00015570922,0.00042494677,0.00046821783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007155997,0.000018811808,0.00027069237,0.00005462957,0.0000049072833,0.000036533223,0.000023257036,0.00005572681,0.99485636,0.00006662175,0.000023211302,0.004517849],"study_design_scores_gemma":[0.000012953858,0.0005692712,0.01617032,0.000011287065,0.000048022364,0.0008114447,0.000040142215,0.0074367328,0.9731058,0.000070698865,0.0017060271,0.000017325781],"about_ca_topic_score_codex":0.0007558373,"about_ca_topic_score_gemma":0.0014245897,"teacher_disagreement_score":0.0022586025,"about_ca_system_score_codex":0.00021016384,"about_ca_system_score_gemma":0.0002479654,"threshold_uncertainty_score":0.007555783},"labels":[],"label_agreement":null},{"id":"W2000590100","doi":"10.1007/s11095-006-9111-5","title":"Transition Metal-Mediated Liposomal Encapsulation of Irinotecan (CPT-11) Stabilizes the Drug in the Therapeutically Active Lactone Conformation","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Liposome; Chemistry; Irinotecan; SN-38; Stereochemistry; Phospholipid; Drug; Lactone; Chromatography; Drug delivery; Membrane; Biophysics; Combinatorial chemistry; Organic chemistry; Biochemistry; Pharmacology","score_opus":0.07871530120952937,"score_gpt":0.3862765323058422,"score_spread":0.30756123109631284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000590100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99266994,0.0008069598,0.003956815,0.00014660526,0.000030316294,0.000023990922,0.000052545915,0.00010260037,0.002210281],"genre_scores_gemma":[0.99488974,0.00028254325,0.0020776996,0.00003630514,0.0000053420636,0.000008401127,0.00003923733,0.0000123078835,0.0026484684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999951,0.0000075437747,0.0000028445388,0.000014105231,0.000012910586,0.000011626361],"domain_scores_gemma":[0.9999558,0.0000087468525,0.000018975668,0.0000042597585,0.000005226836,0.0000070598126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011340836,0.00014689054,0.00010940671,0.00008269122,0.00013666783,0.00023172464,0.0001167196,0.00019813601,0.00089567574],"category_scores_gemma":[0.00013080085,0.00009220309,0.0001014212,0.000054942797,0.00023113856,0.00023092423,0.00013846201,0.00028159772,0.00039153048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000774807,0.0000127203275,0.00005509552,0.000022217928,0.0000027345113,0.000029272034,0.000013378881,0.00013318789,0.99773777,0.00023930645,0.000053654112,0.0016232036],"study_design_scores_gemma":[0.000009694287,0.000076315715,0.00023006066,0.0000016931057,0.0000047033855,0.00005155036,0.0000038010905,0.0005568809,0.9979234,0.000013724866,0.0011253833,0.0000027961328],"about_ca_topic_score_codex":0.000678548,"about_ca_topic_score_gemma":0.0010801711,"teacher_disagreement_score":0.00089567574,"about_ca_system_score_codex":0.00048289826,"about_ca_system_score_gemma":0.00024110243,"threshold_uncertainty_score":0.0035037398},"labels":[],"label_agreement":null},{"id":"W2001171081","doi":"10.1007/s11095-012-0809-2","title":"Peloruside, Laulimalide, and Noscapine Interactions with Beta-Tubulin","year":2012,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Noscapine; Tubulin; Microtubule; Affinities; Antimitotic Agent; Plasma protein binding; Biology; Binding site; Chemistry; Stereochemistry; Computational biology; Pharmacology; Biochemistry; Cell biology; Alkaloid","score_opus":0.24557864165932647,"score_gpt":0.5026699142702488,"score_spread":0.2570912726109223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001171081","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009336262,0.9972633,0.00020619598,0.00015426967,0.00010369837,0.000008439881,0.000033689663,0.000013252531,0.0012834822],"genre_scores_gemma":[0.002791087,0.99478346,0.00025922383,0.00013336119,0.00009462515,0.000011041589,0.000065173685,0.0000025055422,0.0018594828],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999069,0.000010461513,0.000013574842,0.00001995976,0.000035552133,0.000013525156],"domain_scores_gemma":[0.9999242,0.000024302532,0.0000231735,0.0000030458796,0.000015632,0.000009771031],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029565394,0.00088891765,0.0011321985,0.00097061804,0.00022075765,0.0007376036,0.000764806,0.0007327257,0.0018598541],"category_scores_gemma":[0.0002847573,0.00031148293,0.00029870708,0.0011844983,0.00033181853,0.0008341852,0.0004602526,0.0008644591,0.0013752602],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002672415,0.00010191739,0.0002545842,0.012093725,0.00011173171,0.0003008215,0.000037510545,0.0005954832,0.01795384,0.0023841155,0.017681248,0.9482178],"study_design_scores_gemma":[0.000072339986,0.00025307576,0.0017897551,0.0011543174,0.0002199427,0.0014802328,0.000045669185,0.00024920277,0.011724596,0.0012123025,0.98177046,0.000028179902],"about_ca_topic_score_codex":0.0009197092,"about_ca_topic_score_gemma":0.00234949,"teacher_disagreement_score":0.0018598541,"about_ca_system_score_codex":0.000582915,"about_ca_system_score_gemma":0.0005770463,"threshold_uncertainty_score":0.0062217712},"labels":[],"label_agreement":null},{"id":"W2001632155","doi":"10.1007/s11095-012-0829-y","title":"Modeling the Yew Tree Tubulin and a Comparison of its Interaction with Paclitaxel to Human Tubulin","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Paclitaxel; Tubulin; Microtubule; Biology; Binding site; Molecular dynamics; Computational biology; Homology modeling; Biochemistry; Chemistry; Stereochemistry; Biophysics; Genetics; Computational chemistry; Enzyme","score_opus":0.18842445161444463,"score_gpt":0.49129776780835743,"score_spread":0.3028733161939128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001632155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.983265,0.00027568822,0.005377488,0.0003172707,0.00001466926,0.000018127268,0.00036028898,0.00007323315,0.010298323],"genre_scores_gemma":[0.99160576,0.00038940916,0.0041635316,0.000059013768,0.000006687987,0.00003651707,0.00030040028,0.000056150933,0.0033825084],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9999275,0.000020212412,0.0000022544175,0.000012427212,0.00001427051,0.00002327069],"domain_scores_gemma":[0.99975115,0.00015697631,0.00002605371,0.000009709997,0.000028862023,0.00002724662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018886461,0.0003792515,0.0004972533,0.00034986692,0.0005871419,0.00072186644,0.0006905382,0.0013206583,0.0041731205],"category_scores_gemma":[0.0007460759,0.00036341802,0.00044756048,0.0008539679,0.00044107568,0.0005357665,0.00022965798,0.00047879017,0.0002264538],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057511268,0.000034157656,0.0009816571,0.00002909278,0.000013600666,0.00007782186,0.000034154105,0.99363095,0.0016097586,0.0024557582,0.0001972623,0.0008782285],"study_design_scores_gemma":[0.00001889468,0.000020953194,0.00045232128,0.000003619191,0.000005497113,0.000008840856,0.00003267044,0.998396,0.00039827527,0.00040942655,0.00024929788,0.00000427299],"about_ca_topic_score_codex":0.046604883,"about_ca_topic_score_gemma":0.027990412,"teacher_disagreement_score":0.046604883,"about_ca_system_score_codex":0.0014151873,"about_ca_system_score_gemma":0.001244334,"threshold_uncertainty_score":0.09266722},"labels":[],"label_agreement":null},{"id":"W2005711357","doi":"10.1023/b:pham.0000036925.45002.a2","title":"Evidence for Modulation of P-glycoprotein-Mediated Efflux by Methoxypolyethylene Glycol-block-Polycaprolactone Amphiphilic Diblock Copolymers","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Verapamil; Efflux; Chemistry; P-glycoprotein; Biophysics; Endocytosis; Paracellular transport; Membrane; Permeability (electromagnetism); Biochemistry; Cell; Calcium; Biology","score_opus":0.2684487951564432,"score_gpt":0.4934055703730824,"score_spread":0.2249567752166392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005711357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875287,0.006164374,0.0025427002,0.00031695407,0.00004171231,0.0000289629,0.00008448615,0.000038981278,0.00325316],"genre_scores_gemma":[0.99581605,0.0020917584,0.001041157,0.00009823997,0.000029955356,0.000020815627,0.00008703304,0.000009405577,0.00080556574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998597,0.000039484443,0.000014154675,0.00001786069,0.00003809336,0.00003061635],"domain_scores_gemma":[0.9997068,0.00014699738,0.00005623248,0.000034396064,0.000027865117,0.000027630107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030631432,0.00022831895,0.00013760292,0.00017966668,0.00012219125,0.00026808077,0.00014562799,0.00027301483,0.0011149691],"category_scores_gemma":[0.0004263631,0.00012799684,0.00011716891,0.000117873664,0.00025540034,0.00032944404,0.00016089846,0.00039057445,0.00025284663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002249868,0.000026065703,0.00018933469,0.000034395118,0.0000027826788,0.00007672923,0.000009401568,0.0000158144,0.9977658,0.0002251847,0.0000186803,0.0014108225],"study_design_scores_gemma":[0.00003295294,0.00034559093,0.003022587,0.000005129031,0.0000144643445,0.00035663636,0.000009445831,0.0002352153,0.9946355,0.00011402647,0.0012258153,0.0000026116356],"about_ca_topic_score_codex":0.00015504046,"about_ca_topic_score_gemma":0.00014364287,"teacher_disagreement_score":0.0011149691,"about_ca_system_score_codex":0.00017598773,"about_ca_system_score_gemma":0.00010833039,"threshold_uncertainty_score":0.0037299395},"labels":[],"label_agreement":null},{"id":"W2006286058","doi":"10.1007/s11095-004-1188-0","title":"Engineering Polysaccharide-Based Polymeric Micelles to Enhance Permeability of Cyclosporin A Across Caco-2 Cells","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Health Canada","keywords":"Micelle; Polysaccharide; Caco-2; Pharmaceutical technology; Permeability (electromagnetism); Chemistry; Agrégation; Drug carrier; Biophysics; Chemical engineering; Drug delivery; In vitro; Chromatography; Biochemistry; Aqueous solution; Biology; Organic chemistry; Membrane; Immunology; Engineering","score_opus":0.2019748166664326,"score_gpt":0.5717762186772231,"score_spread":0.3698014020107905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006286058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932104,0.0006708473,0.0051241913,0.00010779529,0.00003686908,0.00003841427,0.00005092229,0.00004164504,0.00071896706],"genre_scores_gemma":[0.99201804,0.0005749044,0.0060885292,0.00004708969,0.000009420002,0.000017429104,0.00006899072,0.00001900296,0.0011563908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991035,0.00002004422,0.000009186403,0.000012477112,0.000020020852,0.000027875203],"domain_scores_gemma":[0.99989736,0.00001974028,0.00003736774,0.000006817402,0.0000152234,0.0000234744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022928469,0.00030788098,0.00018263303,0.00017623525,0.0001291648,0.00039670602,0.00013995879,0.0003131208,0.0005697984],"category_scores_gemma":[0.00016499526,0.00018770163,0.00033294183,0.00015689677,0.0001636684,0.00033316694,0.00017581445,0.00054631295,0.00018476677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005258436,0.000021877255,0.000027768767,0.000017542126,0.000003829764,0.00001809031,0.0000074548057,0.00015122625,0.99902153,0.00008830629,0.000010306624,0.00057950965],"study_design_scores_gemma":[0.000022276918,0.00013097643,0.00024059004,0.000002429524,0.000014392897,0.000036212117,0.0000057947345,0.0009563551,0.9978694,0.000013834599,0.0007051254,0.0000025876018],"about_ca_topic_score_codex":0.00066490116,"about_ca_topic_score_gemma":0.0011249192,"teacher_disagreement_score":0.00066490116,"about_ca_system_score_codex":0.00037916453,"about_ca_system_score_gemma":0.00031484143,"threshold_uncertainty_score":0.0027509928},"labels":[],"label_agreement":null},{"id":"W2006362917","doi":"10.1023/b:pham.0000029288.48673.c2","title":"Effect of Gonadectomy and Hormones on Sex Differences in Ketoprofen Enantiomer Glucuronidation and Renal Excretion of Formed Glucuronides in the Rat","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Medical Research Council Canada; Arthritis Society; Purdue University","keywords":"Glucuronidation; Endocrinology; Internal medicine; Metabolite; Microsome; Chemistry; Testosterone (patch); Hormone; Excretion; Biology; Medicine; Enzyme; Biochemistry","score_opus":0.12241290224681542,"score_gpt":0.46585684311519115,"score_spread":0.3434439408683757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006362917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970487,0.0008952281,0.00033259616,0.00010263151,0.00006634253,0.000015477493,0.0007294413,0.000052528736,0.00075718074],"genre_scores_gemma":[0.9860947,0.0020104656,0.0007231246,0.0001757585,0.00007102273,0.00005339963,0.0017613941,0.00009490507,0.009015199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994598,0.000065742104,0.000041495467,0.00012285277,0.00009129198,0.00021883482],"domain_scores_gemma":[0.99859804,0.00028163535,0.00031487655,0.0002198547,0.00008181507,0.0005038181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040420552,0.0010171008,0.00091928826,0.0012441973,0.0004257009,0.00066745246,0.00039286166,0.0005902014,0.003560871],"category_scores_gemma":[0.00063574483,0.00084619113,0.00088198803,0.0006243313,0.0018632732,0.0013103405,0.00042350226,0.0013385192,0.00062428403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.092478596,0.0018848398,0.008694624,0.00012918629,0.00020635013,0.00075596443,0.00036911026,0.00047411377,0.87877566,0.00063922856,0.00030905384,0.01528327],"study_design_scores_gemma":[0.00071625883,0.011534646,0.07210565,0.000021892783,0.0004442634,0.0004842275,0.0005219523,0.0009808919,0.9099995,0.00051425997,0.0025533321,0.00012318938],"about_ca_topic_score_codex":0.0035834562,"about_ca_topic_score_gemma":0.0070349844,"teacher_disagreement_score":0.0035834562,"about_ca_system_score_codex":0.00074637844,"about_ca_system_score_gemma":0.0011634218,"threshold_uncertainty_score":0.011912286},"labels":[],"label_agreement":null},{"id":"W2006512809","doi":"10.1023/b:pham.0000003389.77585.be","title":"Enantioselective Analysis of Ritalinic Acids in Biological Samples by Using a Protein-Based Chiral Stationary Phase","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Enantiomer; Chemistry; Chromatography; Acetic acid; High-performance liquid chromatography; Enantioselective synthesis; Human plasma; Elution; Chiral stationary phase; In vitro; Solvent; Quantitative analysis (chemistry); Stereochemistry; Biochemistry; Catalysis","score_opus":0.207196381377571,"score_gpt":0.5046709568155322,"score_spread":0.2974745754379612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006512809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9371173,0.0025975148,0.052601684,0.00035703587,0.000114025774,0.00016394861,0.00068569224,0.00042450687,0.005938296],"genre_scores_gemma":[0.9434546,0.0034925183,0.04539506,0.0002826537,0.000060245166,0.000137805,0.0012220169,0.0001609399,0.005794072],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996057,0.00011576113,0.00002175556,0.000056615496,0.000114972936,0.000085187436],"domain_scores_gemma":[0.9997352,0.00009433688,0.000038424012,0.000032470205,0.000054179618,0.000045397424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005226232,0.0007152464,0.00044835705,0.0003903738,0.00034449206,0.0005427408,0.0004807422,0.0005005207,0.0006847839],"category_scores_gemma":[0.00045025378,0.00028094018,0.00029632414,0.00030678342,0.00043007347,0.0003929362,0.00033833194,0.0009820173,0.0007446138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018883709,0.000021654809,0.00007510453,0.000021470292,0.0000076273172,0.00006528319,0.00001660582,0.000073938514,0.99777955,0.00017404434,0.000030403398,0.0015454476],"study_design_scores_gemma":[0.0000064760475,0.000047311936,0.00015471425,0.0000016634292,0.000003986822,0.000058849328,0.000008400704,0.00037543915,0.9989286,0.000022531507,0.00038852563,0.0000036550293],"about_ca_topic_score_codex":0.001103343,"about_ca_topic_score_gemma":0.0019162302,"teacher_disagreement_score":0.001103343,"about_ca_system_score_codex":0.00043749704,"about_ca_system_score_gemma":0.00082360505,"threshold_uncertainty_score":0.003174305},"labels":[],"label_agreement":null},{"id":"W2007648100","doi":"10.1023/b:pham.0000045229.87844.21","title":"Novel Long-Circulating Lipid Nanocapsules","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":111,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canada Research Chairs","keywords":"Nanocapsules; Biodistribution; Pharmacokinetics; PEG ratio; In vivo; Liposome; Chemistry; Pharmacology; Conjugate; PEGylation; Polyethylene glycol; Drug carrier; Drug delivery; Dosage form; Chromatography; Nanoparticle; Materials science; Nanotechnology; In vitro; Biochemistry; Medicine; Organic chemistry","score_opus":0.2013702309304076,"score_gpt":0.4513176245320134,"score_spread":0.2499473936016058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007648100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8872304,0.015092267,0.08832548,0.0010027097,0.00062645436,0.00016150215,0.00018911896,0.0006487928,0.006723352],"genre_scores_gemma":[0.9433473,0.0032106056,0.03660652,0.000463771,0.00010908924,0.00012669002,0.00014089463,0.0000989404,0.015896266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999001,0.000017484066,0.0000066371267,0.000029238556,0.000025463267,0.00002102725],"domain_scores_gemma":[0.9998567,0.000037674592,0.00002728585,0.000013615844,0.00003319223,0.000031595682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003438547,0.00027440363,0.0002509747,0.0001475665,0.00019090452,0.00043292236,0.00031887845,0.00047539274,0.00090753974],"category_scores_gemma":[0.00026583663,0.00015845479,0.00016542344,0.00007003827,0.00025071952,0.0005700225,0.00032731675,0.00042981442,0.00048809228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000120138386,0.00003133725,0.000059243717,0.00007683242,0.000009054396,0.00011971304,0.000043027005,0.0002904219,0.9891207,0.0013225498,0.00023242304,0.008574599],"study_design_scores_gemma":[0.000027814034,0.00018256492,0.00022019536,0.000005684941,0.000014893474,0.00015817134,0.00001007372,0.0020518661,0.99023134,0.00021797774,0.006869939,0.000009561841],"about_ca_topic_score_codex":0.0002452577,"about_ca_topic_score_gemma":0.0004517759,"teacher_disagreement_score":0.00090753974,"about_ca_system_score_codex":0.00042278005,"about_ca_system_score_gemma":0.00026595197,"threshold_uncertainty_score":0.0030674934},"labels":[],"label_agreement":null},{"id":"W2008793028","doi":"10.1007/s11095-008-9571-x","title":"Discovery and Development of Toll-Like Receptor 4 (TLR4) Antagonists: A New Paradigm for Treating Sepsis and Other Diseases","year":2008,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":174,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"TLR4; Sepsis; Lipopolysaccharide; Septic shock; Medicine; Immunology; Toll-like receptor; Receptor; Intensive care; Inflammation; Pharmacology; Intensive care medicine; Immune system; Innate immune system; Internal medicine","score_opus":0.22445297526804314,"score_gpt":0.47696831995546535,"score_spread":0.2525153446874222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008793028","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024131399,0.99634546,0.00081273745,0.000632195,0.0006759719,0.000012762306,0.000033933225,0.000022451648,0.0012231413],"genre_scores_gemma":[0.0007678889,0.9961888,0.00085559936,0.0005285266,0.00042797247,0.000013587324,0.00006630081,0.0000031939474,0.0011482409],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997359,0.000027500417,0.000031813874,0.00004748878,0.00012881572,0.000028509423],"domain_scores_gemma":[0.9996147,0.00012275306,0.000064052976,0.000014901593,0.00013075497,0.000052797943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009743348,0.001548046,0.0022151677,0.0020307135,0.00033086265,0.0012924481,0.0015550265,0.0018643838,0.0035904518],"category_scores_gemma":[0.0008744052,0.000422083,0.00061860634,0.00197918,0.0007363079,0.002178415,0.0007544229,0.0032231535,0.0037457088],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021608367,0.00015882506,0.00011641207,0.006734315,0.00008521212,0.00025377606,0.000034807414,0.00045579567,0.00730819,0.0039308514,0.050494436,0.93021125],"study_design_scores_gemma":[0.000094707655,0.00019794662,0.0004244865,0.0007364769,0.00010397604,0.0011369905,0.00003210799,0.00014899534,0.0017462091,0.0017160785,0.9936407,0.000021354559],"about_ca_topic_score_codex":0.00079698354,"about_ca_topic_score_gemma":0.0014785469,"teacher_disagreement_score":0.0035904518,"about_ca_system_score_codex":0.0007611061,"about_ca_system_score_gemma":0.0011362231,"threshold_uncertainty_score":0.01201129},"labels":[],"label_agreement":null},{"id":"W2009530377","doi":"10.1007/s11095-006-9090-6","title":"Fractal Michaelis-Menten Kinetics Under Steady State Conditions: Application to Mibefradil","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Fractional Differential Equations Solutions","field":"Mathematics","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Allard Foundation; Mitacs","keywords":"Fractal; Mibefradil; Kinetics; Steady state (chemistry); Thermodynamics; Power law; Chemistry; Exponent; Statistical physics; Mathematics; Physics; Physical chemistry; Mathematical analysis; Statistics; Biochemistry","score_opus":0.2491966207903665,"score_gpt":0.5242948431898925,"score_spread":0.27509822239952597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009530377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6320359,0.012815831,0.31665194,0.0050603626,0.00051727355,0.00012741007,0.00033128908,0.0007972362,0.03166279],"genre_scores_gemma":[0.9665138,0.003265638,0.021822585,0.00015990315,0.00008246445,0.00005938089,0.00009093168,0.00005025054,0.007954965],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9998307,0.000044241468,0.0000075397747,0.00003761215,0.00004393403,0.000035890655],"domain_scores_gemma":[0.9995764,0.00023111983,0.00006644962,0.00002967466,0.000053550524,0.000042769265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067486515,0.00041449667,0.0013243229,0.00093747536,0.0009653488,0.0012401573,0.00078094366,0.0012351214,0.001232908],"category_scores_gemma":[0.001859401,0.00029782753,0.00083825574,0.00056962005,0.0008867794,0.00096746144,0.00066793803,0.0012712349,0.0002448663],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073507737,0.00040968382,0.0010726241,0.0007585602,0.00008341683,0.000967523,0.0005208151,0.2685987,0.11612705,0.55429304,0.00402301,0.052410558],"study_design_scores_gemma":[0.000061467625,0.00020786178,0.00039686426,0.000019849173,0.000033485947,0.00027972914,0.00005450811,0.9002894,0.028243879,0.065372944,0.0049764332,0.0000635702],"about_ca_topic_score_codex":0.004851502,"about_ca_topic_score_gemma":0.0018028729,"teacher_disagreement_score":0.004851502,"about_ca_system_score_codex":0.002141392,"about_ca_system_score_gemma":0.00107758,"threshold_uncertainty_score":0.015536904},"labels":[],"label_agreement":null},{"id":"W2011199510","doi":"10.1007/s11095-013-1127-z","title":"Dual Physiologically Based Pharmacokinetic Model of Liposomal and Nonliposomal Amphotericin B Disposition","year":2013,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pharmacokinetics; Physiologically based pharmacokinetic modelling; Biodistribution; Pharmacology; Liposome; Amphotericin B; Mononuclear phagocyte system; Chemistry; Pharmacodynamics; Medicine; Antifungal; Pathology; In vitro; Biochemistry","score_opus":0.18783313918380304,"score_gpt":0.45452901220149194,"score_spread":0.26669587301768893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011199510","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45526043,0.006614264,0.5008098,0.0022915844,0.00027567372,0.00048152776,0.002554161,0.00086683343,0.030845681],"genre_scores_gemma":[0.95955247,0.0022351444,0.01606917,0.0004118037,0.00005391889,0.000459563,0.0006339674,0.00008405471,0.020499982],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99984837,0.000037352405,0.000008248685,0.00005287898,0.000027955333,0.000025135974],"domain_scores_gemma":[0.99984384,0.000079106205,0.000029440376,0.000009128313,0.000028025146,0.00001040195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030800956,0.00058753625,0.0008968295,0.00037854732,0.00024396912,0.0012309579,0.0009224649,0.0012744609,0.0019178331],"category_scores_gemma":[0.0006533197,0.0004523055,0.0009681083,0.00024863065,0.00049771235,0.0010272162,0.0004049711,0.0010388601,0.00085111416],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017523217,0.0002596469,0.0020892643,0.0007863404,0.0002728789,0.001557531,0.00035835375,0.6766717,0.24665505,0.048860133,0.00229336,0.018443463],"study_design_scores_gemma":[0.000092562186,0.00015819681,0.0005735266,0.000017726828,0.000080827704,0.0005028923,0.000031317908,0.98268074,0.009888655,0.0037495678,0.0021892728,0.000034747052],"about_ca_topic_score_codex":0.002759097,"about_ca_topic_score_gemma":0.0011354998,"teacher_disagreement_score":0.002759097,"about_ca_system_score_codex":0.0008430483,"about_ca_system_score_gemma":0.0009865115,"threshold_uncertainty_score":0.0064157844},"labels":[],"label_agreement":null},{"id":"W2012192443","doi":"10.1007/s11095-006-0282-x","title":"A New Polymer–Lipid Hybrid Nanoparticle System Increases Cytotoxicity of Doxorubicin Against Multidrug-Resistant Human Breast Cancer Cells","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":299,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto","keywords":"Cytotoxicity; Doxorubicin; Solid lipid nanoparticle; Pharmacology; Chemistry; Doxorubicin Hydrochloride; Trypan blue; Multiple drug resistance; Drug delivery; In vitro; Biochemistry; Chemotherapy; Medicine; Surgery; Organic chemistry","score_opus":0.05532899483376065,"score_gpt":0.37369304473197923,"score_spread":0.3183640498982186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012192443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98830485,0.0012932514,0.00800893,0.00020731219,0.00006802132,0.000060804352,0.00010229456,0.0002460262,0.0017086025],"genre_scores_gemma":[0.9909672,0.0005058708,0.005437537,0.0000986,0.000025413272,0.00003731745,0.0001631412,0.00005123283,0.00271373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990904,0.00001832149,0.000007610544,0.000029316216,0.000017583363,0.00001808255],"domain_scores_gemma":[0.999899,0.000029550218,0.000018602017,0.000008392282,0.0000141823375,0.000030190658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019284672,0.00032455838,0.00029650444,0.0003015501,0.00020314341,0.00035329847,0.00021850296,0.00038324573,0.001634409],"category_scores_gemma":[0.00019250593,0.00020869079,0.00019786227,0.00014584379,0.00023926584,0.0004378112,0.0003023487,0.00047166058,0.00042806496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015005865,0.00003394777,0.0000549312,0.00003509845,0.0000073203955,0.00003514514,0.000014111252,0.0000637534,0.9974419,0.00009993593,0.000045895686,0.0020178617],"study_design_scores_gemma":[0.000055527616,0.0003761957,0.0005089786,0.000003783671,0.0000326782,0.00012854375,0.0000062203485,0.00068482896,0.995915,0.000024736057,0.002256549,0.0000070153296],"about_ca_topic_score_codex":0.00049605157,"about_ca_topic_score_gemma":0.00077638996,"teacher_disagreement_score":0.001634409,"about_ca_system_score_codex":0.00036043473,"about_ca_system_score_gemma":0.00025010423,"threshold_uncertainty_score":0.0054676533},"labels":[],"label_agreement":null},{"id":"W2012859709","doi":"10.1007/s11095-009-9951-x","title":"Characterization of a Microsphere Formulation Containing Glucose Oxidase and its In Vivo Efficacy in a Murine Solid Tumor Model","year":2009,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"In vivo; Microsphere; Glucose oxidase; Chemistry; Solid tumor; Pharmaceutical technology; Pharmacology; Medicine; Biochemistry; Biology; Enzyme; Cancer; Internal medicine; Chromatography; Biotechnology; Chemical engineering","score_opus":0.2404391843371592,"score_gpt":0.5334837759223248,"score_spread":0.2930445915851656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012859709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850578,0.0008807313,0.01312707,0.00006488728,0.000026956672,0.00006521347,0.00020436577,0.000069155925,0.0005038079],"genre_scores_gemma":[0.988941,0.00041631795,0.008951018,0.000028593977,0.000014524605,0.00003796046,0.00026384433,0.000031912517,0.0013148878],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999207,0.000012166768,0.000005444939,0.000021508326,0.000022948414,0.000017147524],"domain_scores_gemma":[0.99983454,0.00004337269,0.0000550917,0.000011318607,0.00002981743,0.000025934434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028465144,0.0002661605,0.00015890857,0.0001946015,0.00012085494,0.00013023781,0.0001783354,0.00027173173,0.00049930107],"category_scores_gemma":[0.00023253511,0.000105443236,0.00018150236,0.00011102182,0.0001579514,0.00022620693,0.000066720466,0.00030366512,0.00011007834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063704756,0.000014683723,0.000043846612,0.00000885348,0.0000018217557,0.000011882705,0.000004541731,0.000042080905,0.9992144,0.000020027861,0.0000074594736,0.0005666341],"study_design_scores_gemma":[0.0000051716675,0.00032903042,0.00059862493,7.783642e-7,0.0000075210082,0.00003464593,0.0000023215114,0.00035072953,0.9984251,0.000005067253,0.00023956657,0.0000015211085],"about_ca_topic_score_codex":0.00092283625,"about_ca_topic_score_gemma":0.0007481032,"teacher_disagreement_score":0.00092283625,"about_ca_system_score_codex":0.00020691137,"about_ca_system_score_gemma":0.00018153178,"threshold_uncertainty_score":0.0018349886},"labels":[],"label_agreement":null},{"id":"W2015220555","doi":"10.1007/s11095-010-0197-4","title":"Bisethylnorspermine Lipopolyamine as Potential Delivery Vector for Combination Drug/Gene Anticancer Therapies","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Cancer Institute; National Institutes of Health","keywords":"Gene delivery; Transfection; Cytotoxicity; Polyamine; Drug delivery; Cancer cell; Chemistry; Luciferase; Pharmacology; Genetic enhancement; Biology; In vitro; Cancer; Cancer research; Gene; Biochemistry; Genetics","score_opus":0.05097517480789226,"score_gpt":0.43701323766222294,"score_spread":0.3860380628543307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015220555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9547705,0.0073942067,0.032815147,0.00019580229,0.000084081745,0.00011934175,0.00017355494,0.00020689306,0.0042403876],"genre_scores_gemma":[0.9700686,0.003417617,0.018622426,0.000056391807,0.000020682568,0.00007439957,0.00026972953,0.0000520104,0.007418154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998987,0.000021177491,0.000007799298,0.00002790432,0.000029896737,0.0000145738695],"domain_scores_gemma":[0.99995005,0.000010184471,0.000016175583,0.0000046878663,0.000007484462,0.000011315188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022931818,0.00027549337,0.00025449076,0.00019016964,0.000112463254,0.00029871817,0.00023498813,0.0002963312,0.0007105265],"category_scores_gemma":[0.000102354206,0.00014307856,0.00016411659,0.0001860976,0.0001709629,0.00040130178,0.00022086628,0.0003618542,0.00034782928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007009008,0.000018383189,0.000049657814,0.000040474173,0.0000038106057,0.000038197584,0.000010613187,0.00010932208,0.994518,0.0003010005,0.000042724998,0.0047977264],"study_design_scores_gemma":[0.00001220536,0.0002339064,0.00035492925,0.000004373399,0.000023557834,0.00015616858,0.0000060441316,0.001439706,0.99397343,0.00004821052,0.0037431235,0.0000044081285],"about_ca_topic_score_codex":0.0004820603,"about_ca_topic_score_gemma":0.00053996785,"teacher_disagreement_score":0.0007105265,"about_ca_system_score_codex":0.00031020594,"about_ca_system_score_gemma":0.00025625993,"threshold_uncertainty_score":0.002376914},"labels":[],"label_agreement":null},{"id":"W2018196946","doi":"10.1007/s11095-012-0853-y","title":"The Effect of Metal-Chelating Polymers (MCPs) for 111In Complexed via the Streptavidin-Biotin System to Trastuzumab Fab Fragments on Tumor and Normal Tissue Distribution in Mice","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biodistribution; Chelation; Chemistry; Streptavidin; Molecular biology; Nuclear chemistry; Biotin; Biochemistry; In vitro; Biology","score_opus":0.084502996664628,"score_gpt":0.4639564727075581,"score_spread":0.37945347604293006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018196946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962496,0.0012137479,0.0014037944,0.000117391115,0.000039394665,0.000020229305,0.0001198417,0.000060306873,0.00077567826],"genre_scores_gemma":[0.9951814,0.00054333126,0.0017881652,0.00006756749,0.000015665812,0.000020221223,0.00013357008,0.000026698888,0.0022233368],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998287,0.000030850664,0.000008830287,0.000047232967,0.000025150204,0.000059230308],"domain_scores_gemma":[0.9997429,0.00010234343,0.000057507605,0.00001598992,0.000021533744,0.000059627833],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023789961,0.00038800618,0.00021660888,0.0001836842,0.00010739442,0.00022662876,0.0002674094,0.00047256946,0.0009774417],"category_scores_gemma":[0.00026948328,0.00027552436,0.00021627065,0.00013622249,0.0003101527,0.00022938334,0.0001258466,0.0005075613,0.00018444746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009735102,0.00003820426,0.00005986782,0.000033129694,0.00000505319,0.00002057605,0.00001195915,0.00013085564,0.9976426,0.000046294394,0.000032936365,0.0010049675],"study_design_scores_gemma":[0.000023679348,0.0006857482,0.0004924344,0.0000017640137,0.0000148737,0.00003339075,0.0000036322115,0.00047623378,0.997834,0.000010022433,0.00042152722,0.0000027355316],"about_ca_topic_score_codex":0.0013541701,"about_ca_topic_score_gemma":0.0011814445,"teacher_disagreement_score":0.0013541701,"about_ca_system_score_codex":0.00032333782,"about_ca_system_score_gemma":0.0002467626,"threshold_uncertainty_score":0.0032697916},"labels":[],"label_agreement":null},{"id":"W2019121504","doi":"10.1007/s11095-005-4595-y","title":"Solid-State Fluorescence Studies of Some Polymorphs of Diflunisal*","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Photochemistry and Electron Transfer Studies","field":"Chemistry","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Future Earth","funders":"","keywords":"Chemistry; Fluorescence; Excited state; Exciton; Intermolecular force; Diflunisal; Excitation; Molecule; Fluorescence spectroscopy; Luminescence; Analytical Chemistry (journal); Crystallography; Materials science; Atomic physics; Organic chemistry","score_opus":0.1939719338228766,"score_gpt":0.5135855279093902,"score_spread":0.3196135940865136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019121504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99615735,0.00064024614,0.0008484836,0.00006741436,0.00000770989,0.000009988888,0.00014243813,0.000016405482,0.0021099288],"genre_scores_gemma":[0.998423,0.00019475394,0.0005666842,0.000011144368,0.0000033972228,0.0000034137247,0.000104089406,0.000006314518,0.00068709615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999044,0.000025228357,0.00000491617,0.000018018032,0.000020742724,0.000026720021],"domain_scores_gemma":[0.9998344,0.00008730128,0.000024380737,0.000015272972,0.00002246155,0.000016189855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018690637,0.00013117131,0.00013528063,0.00018688498,0.00031229827,0.00020250135,0.0002776916,0.00023473844,0.002515576],"category_scores_gemma":[0.0003987257,0.00008188114,0.000089522895,0.00023074244,0.00034959087,0.00036566547,0.00012731492,0.00031062117,0.00016136229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019011124,0.00010905359,0.0010775785,0.00012892063,0.000017083123,0.00018928501,0.00027024763,0.00040808198,0.98686856,0.0010084986,0.00035019682,0.0076713497],"study_design_scores_gemma":[0.000055138695,0.00067551935,0.004104015,0.000008847881,0.000016227345,0.00020099062,0.00017125513,0.002738383,0.9895867,0.00015465535,0.0022764842,0.000011764453],"about_ca_topic_score_codex":0.0021513556,"about_ca_topic_score_gemma":0.0013510752,"teacher_disagreement_score":0.002515576,"about_ca_system_score_codex":0.0002335824,"about_ca_system_score_gemma":0.00010946578,"threshold_uncertainty_score":0.008415461},"labels":[],"label_agreement":null},{"id":"W2026446857","doi":"10.1023/b:pham.0000026433.27773.47","title":"Involvement of P-Glycoprotein in the Transport of Saquinavir and Indinavir in Rat Brain Microvessel Endothelial and Microglia Cell Lines","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Merck Canada; Ontario HIV Treatment Network","keywords":"Saquinavir; Indinavir; P-glycoprotein; Blood–brain barrier; Molecular biology; Cell culture; Endothelial stem cell; Ritonavir; Biology; Protease; Chemistry; Pharmacology; Biochemistry; Virology; Endocrinology; Enzyme; Central nervous system; Virus","score_opus":0.07578864608295044,"score_gpt":0.3958622981915678,"score_spread":0.3200736521086174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026446857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956072,0.0020701264,0.0010361895,0.00006447068,0.000011125006,0.000006493789,0.00024449397,0.000016563441,0.00094320945],"genre_scores_gemma":[0.9958204,0.0013655793,0.001373863,0.000022455317,0.000008176693,0.000011892945,0.00038818552,0.000006434881,0.0010030282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984205,0.00004461087,0.000011740319,0.000018215107,0.000026347838,0.000056977693],"domain_scores_gemma":[0.99993694,0.00002144802,0.000009353715,0.000009743463,0.0000151355935,0.00000748712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015695556,0.00018370256,0.0002068076,0.00020286157,0.00025422766,0.0004113331,0.0001790056,0.0002918363,0.00047021732],"category_scores_gemma":[0.00014930486,0.00015486243,0.00031079358,0.00021493301,0.00016385374,0.00046429582,0.00010238329,0.00035248295,0.00020988249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005264205,0.000049310784,0.00090436824,0.00007377252,0.000017548864,0.00029076484,0.00012428123,0.000128573,0.99508286,0.00050058926,0.000054481534,0.0022469542],"study_design_scores_gemma":[0.000044573175,0.0009874878,0.034648906,0.000024734649,0.00009059845,0.001837429,0.00035516507,0.0034511546,0.9549013,0.0004910197,0.0031445723,0.000022996595],"about_ca_topic_score_codex":0.0029718578,"about_ca_topic_score_gemma":0.0025261645,"teacher_disagreement_score":0.0029718578,"about_ca_system_score_codex":0.00037965155,"about_ca_system_score_gemma":0.00022819206,"threshold_uncertainty_score":0.005909145},"labels":[],"label_agreement":null},{"id":"W2026934985","doi":"10.1007/s11095-006-9779-6","title":"Solid-State Characterization of Buspirone Hydrochloride Polymorphs","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Apotex Pharmachem (Canada); Western University","funders":"","keywords":"Powder diffraction; Differential scanning calorimetry; Raman spectroscopy; Fourier transform infrared spectroscopy; Scanning electron microscope; Thermal analysis; Analytical Chemistry (journal); Infrared spectroscopy; Spectroscopy; Materials science; Polymorphism (computer science); Thermogravimetric analysis; Crystallography; Chemistry; Chromatography; Thermal; Organic chemistry; Chemical engineering; Optics; Thermodynamics","score_opus":0.061441691695260425,"score_gpt":0.41622574796746115,"score_spread":0.3547840562722007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026934985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99562186,0.00052189187,0.0012382715,0.0000526312,0.000013496935,0.000019799158,0.0006864579,0.00003947052,0.0018060576],"genre_scores_gemma":[0.99611926,0.00034170464,0.0010622818,0.00001908531,0.0000065116124,0.000014865637,0.00069064426,0.000018160754,0.0017275364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999151,0.00001625985,0.000006189125,0.000015327,0.000034652232,0.000012450059],"domain_scores_gemma":[0.99990165,0.000039126095,0.000017644732,0.000008846431,0.00002364265,0.000009167018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009021017,0.00010907151,0.00013349815,0.00017890203,0.00017204335,0.00015864635,0.00012401491,0.000099925936,0.0033754846],"category_scores_gemma":[0.00030967142,0.00008948465,0.00010646673,0.00019961147,0.00016668504,0.00018720691,0.00007867348,0.0002011608,0.0003246348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072460977,0.000046417586,0.00073248136,0.000056174817,0.000019495783,0.000080844235,0.00007444162,0.000366797,0.9914043,0.0002994438,0.00031771135,0.005877293],"study_design_scores_gemma":[0.000056317072,0.0006765487,0.0076386533,0.000005644873,0.000021432297,0.0001575331,0.00007282566,0.0040181517,0.9837013,0.00008598112,0.003550722,0.000014833745],"about_ca_topic_score_codex":0.0007645823,"about_ca_topic_score_gemma":0.0012659844,"teacher_disagreement_score":0.0033754846,"about_ca_system_score_codex":0.00010924763,"about_ca_system_score_gemma":0.00013042783,"threshold_uncertainty_score":0.0112921},"labels":[],"label_agreement":null},{"id":"W2027520352","doi":"10.1007/s11095-004-7686-2","title":"Unidirectional Inhibition of Lipid Transfer Protein I-Mediated Transfer of Cholesteryl Esters Between High-Density and Low-Density Lipoproteins by Amphotericin B Lipid Complex","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Pesticide Exposure and Toxicity","field":"Agricultural and Biological Sciences","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Chemistry; Plant lipid transfer proteins; Cholesteryl ester; Cholesterylester transfer protein; Cholesterol; High-density lipoprotein; Phospholipid transfer protein; Biochemistry; Chromatography; Endocrinology; Lipoprotein; Phospholipid; Biology","score_opus":0.0925476825872697,"score_gpt":0.33226802002399525,"score_spread":0.23972033743672555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027520352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99144894,0.00041054454,0.006660082,0.00007370021,0.000027999413,0.000050623472,0.000083243474,0.000100047204,0.001144742],"genre_scores_gemma":[0.99480224,0.0002381452,0.0027763895,0.00003449754,0.00000693738,0.00005623752,0.00013183561,0.000028332366,0.0019255494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977237,0.00004920842,0.000021866363,0.00004488154,0.0000474805,0.000064337866],"domain_scores_gemma":[0.9997243,0.00010640475,0.000063384614,0.000040419516,0.000026360067,0.000039149312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042844753,0.00055442785,0.0003394561,0.00017728897,0.00021270169,0.00047810783,0.00040742627,0.0004090136,0.0009708493],"category_scores_gemma":[0.00036025504,0.00023431047,0.00029540513,0.00014730684,0.00040947084,0.0003864657,0.00043083486,0.0007907079,0.0004057619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021479321,0.000019501056,0.000050337432,0.000026012607,0.00000437722,0.000022801132,0.000021270898,0.00004063966,0.9988462,0.0002246452,0.000019462726,0.00050995953],"study_design_scores_gemma":[0.000014966289,0.00005848937,0.0001608391,0.0000018015751,0.0000036613633,0.00001761841,0.0000040289556,0.0004995838,0.99906725,0.000019474186,0.00015010266,0.0000020481193],"about_ca_topic_score_codex":0.00067948794,"about_ca_topic_score_gemma":0.00042382072,"teacher_disagreement_score":0.0009708493,"about_ca_system_score_codex":0.00046867086,"about_ca_system_score_gemma":0.00034447844,"threshold_uncertainty_score":0.003400445},"labels":[],"label_agreement":null},{"id":"W2029332664","doi":"10.1007/s11095-006-9898-0","title":"Structural Relaxation of Acetaminophen Glass","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Material Dynamics and Properties","field":"Materials Science","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Enthalpy; Thermodynamics; Differential scanning calorimetry; Chemistry; Glass transition; Kinetics; Relaxation (psychology); Hydrogen bond; Intermolecular force; Molecule; Materials science; Organic chemistry; Polymer","score_opus":0.14783788688839564,"score_gpt":0.4252684779212144,"score_spread":0.27743059103281875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029332664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99633753,0.00043185,0.0005697271,0.00010236736,0.000015813372,0.0000063921602,0.000077064884,0.000011890227,0.0024473586],"genre_scores_gemma":[0.998142,0.00024121896,0.0002023929,0.000036321013,0.0000064109354,0.00000369462,0.00007389671,0.000007748722,0.001286296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999404,0.000007336941,0.0000014811271,0.000010457275,0.000015732998,0.000024686631],"domain_scores_gemma":[0.9999081,0.000035760553,0.000021071883,0.00000671283,0.00001449041,0.000013758185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009236034,0.00013615469,0.00008566034,0.00016580765,0.0003229121,0.00020041665,0.00023828758,0.00017100334,0.0037043025],"category_scores_gemma":[0.00020846885,0.00013559317,0.0000845303,0.00015545644,0.00037547314,0.00030468823,0.00018283531,0.0003340419,0.00018781335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029312287,0.000029052117,0.0010326465,0.000057380683,0.000011649613,0.0001818348,0.00022252981,0.00093089824,0.9907803,0.0008218984,0.00027126915,0.005367356],"study_design_scores_gemma":[0.000041506653,0.00047881712,0.03696139,0.000023303048,0.000028384167,0.00017509366,0.00062103785,0.030310845,0.92722803,0.00067591236,0.0034169056,0.00003872511],"about_ca_topic_score_codex":0.003598465,"about_ca_topic_score_gemma":0.0025016763,"teacher_disagreement_score":0.0037043025,"about_ca_system_score_codex":0.00022630054,"about_ca_system_score_gemma":0.00020123755,"threshold_uncertainty_score":0.012392163},"labels":[],"label_agreement":null},{"id":"W2029349015","doi":"10.1007/s11095-006-9934-0","title":"Insights into the Role of Electrostatic Forces on the Behavior of Dry Pharmaceutical Particulate Systems","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Granular flow and fluidized beds","field":"Engineering","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Agglomerate; Homogeneity (statistics); Economies of agglomeration; Electrostatics; Surface charge; Mixing (physics); Particulates; Materials science; Static electricity; Chemical engineering; Nanotechnology; Chemistry; Chemical physics; Composite material","score_opus":0.05573088940495491,"score_gpt":0.37223764019768035,"score_spread":0.31650675079272544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029349015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9446066,0.00543698,0.04098767,0.0009981033,0.0001746724,0.000025897623,0.00010988968,0.00010235902,0.0075578676],"genre_scores_gemma":[0.9956201,0.0013564683,0.0019722404,0.000101047335,0.000047638743,0.0000039027927,0.000042238044,0.000008530746,0.0008479176],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9998777,0.000016797216,0.000006547892,0.000017342289,0.00005226216,0.000029435534],"domain_scores_gemma":[0.9997826,0.0001068628,0.000038339746,0.000021183881,0.000028150851,0.000022849297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002392168,0.00028001016,0.00038588973,0.00032142247,0.00026117315,0.00064397365,0.00025721604,0.00047990936,0.0012073013],"category_scores_gemma":[0.00054007,0.00016933017,0.00024499872,0.00014537825,0.0006802486,0.00088450016,0.0003817722,0.0005417962,0.0001768087],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005698133,0.00026155816,0.0035667752,0.0005447016,0.00005818523,0.000658214,0.0002125518,0.033509374,0.89673775,0.028943753,0.0007615229,0.034175858],"study_design_scores_gemma":[0.00020344499,0.0010626635,0.029725585,0.00006611622,0.00010213937,0.0009288001,0.00044290716,0.56756175,0.34274203,0.04847312,0.008555056,0.00013636134],"about_ca_topic_score_codex":0.0005994756,"about_ca_topic_score_gemma":0.00042041048,"teacher_disagreement_score":0.0012073013,"about_ca_system_score_codex":0.000225009,"about_ca_system_score_gemma":0.0001904531,"threshold_uncertainty_score":0.0040388107},"labels":[],"label_agreement":null},{"id":"W2029657034","doi":"10.1007/s11095-007-9507-x","title":"Microdomain pH Gradient and Kinetics Inside Composite Polymeric Membranes of pH and Glucose Sensitivity","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Hydrogels: synthesis, properties, applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Membrane; Glucose oxidase; Chemistry; Chromatography; Diffusion; Kinetics; Synthetic membrane; pH indicator; Analytical Chemistry (journal); Biosensor; Biochemistry; Organic chemistry","score_opus":0.07138827197712029,"score_gpt":0.38276151969194594,"score_spread":0.31137324771482566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029657034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99495715,0.00040280906,0.0040009404,0.000037192374,0.0000124856915,0.0000067099704,0.000055373257,0.000043818432,0.00048353526],"genre_scores_gemma":[0.99703205,0.0001899055,0.0018898809,0.000017782313,0.0000057713924,0.000008990555,0.000043705644,0.000020790978,0.00079106743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999249,0.000009439694,0.000003152757,0.000020099196,0.000015644795,0.000026869806],"domain_scores_gemma":[0.9997632,0.0001056499,0.00005850416,0.000016860224,0.000018771076,0.000036914516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017533283,0.00015047124,0.00015735102,0.00011097873,0.00011528538,0.0004001521,0.00023638226,0.00022778318,0.00066539913],"category_scores_gemma":[0.00027933152,0.00017686113,0.00015025976,0.00009892418,0.00023752882,0.0005192665,0.00016713895,0.0005245261,0.00017154423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009928948,0.000008308634,0.00007498223,0.00001740144,0.0000026162236,0.000021869928,0.00002027694,0.00020975809,0.9985879,0.00029878184,0.000019761188,0.00063904066],"study_design_scores_gemma":[0.0000067832057,0.000030831397,0.00035314157,0.0000019618303,0.0000031718955,0.000023852006,0.000009215223,0.0022977358,0.996958,0.000067030254,0.00024376242,0.00000449387],"about_ca_topic_score_codex":0.0003330666,"about_ca_topic_score_gemma":0.00030152884,"teacher_disagreement_score":0.00066539913,"about_ca_system_score_codex":0.00040388788,"about_ca_system_score_gemma":0.00013241582,"threshold_uncertainty_score":0.0029304028},"labels":[],"label_agreement":null},{"id":"W2029865876","doi":"10.1007/s11095-010-0196-5","title":"Paclitaxel-Loaded, Folic-Acid-Targeted and TAT-Peptide-Conjugated Polymeric Liposomes: In Vitro and In Vivo Evaluation","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Institute for Basic Science","keywords":"In vivo; Paclitaxel; Folate receptor; Chemistry; In vitro; A549 cell; Liposome; Peptide; Calcein; Pharmacology; Intracellular; Biochemistry; Cancer cell; Biology; Cancer; Membrane","score_opus":0.08687377019822548,"score_gpt":0.4168372462834626,"score_spread":0.32996347608523713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029865876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99021846,0.002561942,0.005882741,0.000075242795,0.000030946623,0.0000722685,0.00022826195,0.000073342824,0.00085691223],"genre_scores_gemma":[0.9926779,0.0016397915,0.0033538633,0.000026044243,0.0000091514885,0.000040917195,0.00027715403,0.000025702504,0.0019494813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989057,0.00002664009,0.0000096933445,0.00002219766,0.000022101129,0.000028830638],"domain_scores_gemma":[0.99986315,0.00005296879,0.000029724162,0.000011224283,0.000023300945,0.000019659386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004257261,0.00033287995,0.00022996121,0.0002555024,0.00014906531,0.0001801793,0.00018389833,0.00032750497,0.00069147657],"category_scores_gemma":[0.0002404195,0.0001690888,0.00019475799,0.00021963213,0.00020762993,0.00031993844,0.00010800053,0.00034682945,0.0002015371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056212954,0.000076685465,0.000120842844,0.00006187088,0.000008492594,0.000043447326,0.000029767109,0.00020020487,0.99681157,0.00007246129,0.00002812424,0.001984439],"study_design_scores_gemma":[0.000025473973,0.00057824905,0.0005553364,0.000002935535,0.00002853815,0.00007126327,0.0000090399635,0.00071618403,0.99748355,0.000015202184,0.00051088823,0.000003365858],"about_ca_topic_score_codex":0.0009966979,"about_ca_topic_score_gemma":0.0008145269,"teacher_disagreement_score":0.0009966979,"about_ca_system_score_codex":0.00023710026,"about_ca_system_score_gemma":0.00021692118,"threshold_uncertainty_score":0.0023131967},"labels":[],"label_agreement":null},{"id":"W2030171027","doi":"10.1007/s11095-010-0210-y","title":"Cholesterol as a Potential Target for Castration-Resistant Prostate Cancer","year":2010,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Prostate cancer; Androgen deprivation therapy; Androgen; Androgen receptor; Cholesterol; Cancer; Cancer research; Internal medicine; Endocrinology; Medicine; Tumor progression; Biology; Hormone","score_opus":0.15322964209884452,"score_gpt":0.524718396447473,"score_spread":0.3714887543486285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030171027","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021132462,0.9979948,0.00018594722,0.00035237873,0.00024565548,0.000005827919,0.000023754415,0.000009979646,0.00097036856],"genre_scores_gemma":[0.0012515128,0.9969704,0.0002609016,0.00027526257,0.00021792304,0.000009231584,0.000049189894,0.000001936736,0.00096364494],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998609,0.000022155846,0.000015764457,0.000022759781,0.000059341677,0.000019112891],"domain_scores_gemma":[0.9998272,0.00006136753,0.000026726957,0.000006741322,0.000052223448,0.000025760435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060830865,0.00094468973,0.0017051835,0.001506627,0.0002575682,0.0009436259,0.00079205784,0.0010963791,0.0026691952],"category_scores_gemma":[0.00041442772,0.00027949005,0.00038364693,0.0016052029,0.0005434971,0.0009828017,0.00052830135,0.0019226567,0.0023212302],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031022972,0.0001504075,0.00019157262,0.0076012705,0.00011892723,0.0004058446,0.000030302288,0.00044704575,0.0055338517,0.004458713,0.043598935,0.93715286],"study_design_scores_gemma":[0.0001087308,0.00016587166,0.0007295407,0.0009856938,0.00017011494,0.0012619977,0.00003844864,0.00019369906,0.0014446621,0.0017483449,0.9931316,0.000021279311],"about_ca_topic_score_codex":0.0013128164,"about_ca_topic_score_gemma":0.003399944,"teacher_disagreement_score":0.0026691952,"about_ca_system_score_codex":0.0008256335,"about_ca_system_score_gemma":0.00095607573,"threshold_uncertainty_score":0.008929312},"labels":[],"label_agreement":null},{"id":"W2032543735","doi":"10.1007/s11095-005-9258-5","title":"Transport Kinetics of Iron Chelators and Their Chelates in Caco-2 Cells","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Deferiprone; Chemistry; Deferoxamine; Kinetics; Chelation; Bioavailability; Efflux; Caco-2; Biophysics; Reaction rate constant; Monolayer; Paracellular transport; Permeability (electromagnetism); Nuclear chemistry; Analytical Chemistry (journal); Biochemistry; Chromatography; Inorganic chemistry; In vitro; Pharmacology; Membrane","score_opus":0.09419503280270013,"score_gpt":0.43648552891519965,"score_spread":0.3422904961124995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032543735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819296,0.005491095,0.003967049,0.0007922137,0.00015024329,0.000057893903,0.0020254382,0.00022538578,0.0053609894],"genre_scores_gemma":[0.979756,0.002266847,0.0042831805,0.00022151394,0.000039464336,0.000053842778,0.0020147236,0.000111596964,0.011252867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993299,0.0001960644,0.000059587397,0.00014057425,0.00010690429,0.00016704116],"domain_scores_gemma":[0.99920386,0.00033634945,0.00007784641,0.00007667724,0.00025989694,0.000045310426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007762582,0.00034289865,0.0013875379,0.0003125708,0.00046461856,0.0011183199,0.00052669615,0.0010266805,0.0021003005],"category_scores_gemma":[0.0009233627,0.00044608527,0.0007362124,0.00072122423,0.00044669717,0.0010468634,0.00019762733,0.0008227944,0.0010893901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009062788,0.0001316006,0.0016588687,0.00045463452,0.00011196536,0.00029868705,0.0008517888,0.0015212963,0.97498816,0.0013813344,0.0015525718,0.007986374],"study_design_scores_gemma":[0.000276528,0.0015560978,0.010780106,0.000051743267,0.0001929354,0.00050329755,0.00085081474,0.02617859,0.9451056,0.00034956253,0.014027023,0.00012773088],"about_ca_topic_score_codex":0.01914198,"about_ca_topic_score_gemma":0.008873545,"teacher_disagreement_score":0.01914198,"about_ca_system_score_codex":0.0017421973,"about_ca_system_score_gemma":0.00090103666,"threshold_uncertainty_score":0.038061082},"labels":[],"label_agreement":null},{"id":"W2032879526","doi":"10.1007/s11095-004-7675-5","title":"Effect of Pluronic P85 on ATPase Activity of Drug Efflux Transporters","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Supratek Pharma (Canada)","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health; Wellcome Trust","keywords":"Efflux; Chemistry; Multidrug resistance-associated protein 2; ATPase; ATP-binding cassette transporter; Transporter; ATP hydrolysis; Poloxamer; Biochemistry; Intracellular; Pharmacology; Drug; Biophysics; Enzyme; Biology","score_opus":0.07284962300036604,"score_gpt":0.457988491930266,"score_spread":0.3851388689298999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032879526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971727,0.00095610315,0.00041413563,0.000103247956,0.000046612615,0.000013194115,0.00010610312,0.000020957239,0.0011669429],"genre_scores_gemma":[0.9974389,0.0005295296,0.00048101286,0.000046208334,0.000020154801,0.000009897149,0.00023675674,0.000011394742,0.0012260255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952257,0.00014242975,0.000064571504,0.000041103725,0.000082752435,0.00014645961],"domain_scores_gemma":[0.9995092,0.00026395434,0.000059655693,0.00004455814,0.00006140907,0.00006120012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000478181,0.0003457781,0.00045611648,0.00020415544,0.0002474201,0.00048404466,0.00024951142,0.00041579708,0.0017380194],"category_scores_gemma":[0.0009561919,0.00020266398,0.00032104115,0.00040929875,0.00043957695,0.0005614774,0.00027567282,0.0008448903,0.00026422727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0048497748,0.00038065517,0.00061790855,0.00018076498,0.000054188553,0.00021489743,0.0001504154,0.00030141624,0.984984,0.00047585962,0.00023296662,0.0075573237],"study_design_scores_gemma":[0.00011449851,0.0016619796,0.0035033987,0.000009227932,0.000052198196,0.00014390134,0.000057763038,0.0013029882,0.99174833,0.000055414293,0.0013394117,0.000010839224],"about_ca_topic_score_codex":0.0028496007,"about_ca_topic_score_gemma":0.0019846295,"teacher_disagreement_score":0.0028496007,"about_ca_system_score_codex":0.0003636941,"about_ca_system_score_gemma":0.00049010303,"threshold_uncertainty_score":0.0058142543},"labels":[],"label_agreement":null},{"id":"W2033156599","doi":"10.1007/s11095-008-9561-z","title":"Intra and Inter-Molecular Interactions Dictate the Aggregation State of Irinotecan Co-Encapsulated with Floxuridine Inside Liposomes","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Celator Pharmaceuticals (Canada)","funders":"Uppsala Universitet; University of British Columbia","keywords":"Floxuridine; Liposome; Irinotecan; Chemistry; Pharmacology; Pharmaceutical technology; Biophysics; Biochemistry; Medicine; Chromatography; Biology; Chemotherapy; Internal medicine; Fluorouracil; Cancer","score_opus":0.08950621305233872,"score_gpt":0.40078679173013415,"score_spread":0.31128057867779546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033156599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99886703,0.00015535658,0.0004019269,0.000021140677,0.0000030619208,0.000003964015,0.000018501387,0.000008775734,0.0005201854],"genre_scores_gemma":[0.9989737,0.00008535731,0.00041270803,0.000008502821,0.0000018578627,0.000004218356,0.000027179773,0.000005515759,0.0004808745],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999143,0.000018059396,0.000007026728,0.000017205432,0.000019539717,0.00002391425],"domain_scores_gemma":[0.99992216,0.000027823344,0.000021269983,0.000006653053,0.000008634704,0.000013509829],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018512104,0.00014917493,0.00013431086,0.00010759018,0.00013624651,0.00025314864,0.00011615303,0.00014499671,0.0006436574],"category_scores_gemma":[0.00022671022,0.0001075268,0.00009944323,0.00008677642,0.00019834886,0.0003533653,0.00014235298,0.00025282713,0.00016155165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014598113,0.000013659015,0.0002650526,0.000017765733,0.0000044641733,0.000032365268,0.000031073352,0.00019275042,0.9983783,0.00018748353,0.000025422767,0.0007055388],"study_design_scores_gemma":[0.000008664236,0.00005675887,0.0011402346,0.0000020459233,0.000008142402,0.000031109095,0.000010892538,0.0023142165,0.99606484,0.000017576422,0.0003414485,0.000004087956],"about_ca_topic_score_codex":0.00063540286,"about_ca_topic_score_gemma":0.0007305416,"teacher_disagreement_score":0.0006436574,"about_ca_system_score_codex":0.00035092403,"about_ca_system_score_gemma":0.0001385419,"threshold_uncertainty_score":0.0025461316},"labels":[],"label_agreement":null},{"id":"W2035644343","doi":"10.1007/s11095-014-1336-0","title":"In Vitro and In Situ Evaluation of pH-Dependence of Atazanavir Intestinal Permeability and Interactions with Acid-Reducing Agents","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Atazanavir; Chemistry; Ileum; Intestinal permeability; Jejunum; Pharmacology; Biochemistry; Efflux; Permeability (electromagnetism); Bioavailability; Chromatography; Internal medicine; Membrane; Biology; Immunology; Medicine","score_opus":0.22594472538073795,"score_gpt":0.5127677129813628,"score_spread":0.28682298760062486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035644343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923039,0.0014679355,0.003126251,0.000070112466,0.00003743028,0.000023950533,0.000328896,0.00003271877,0.002608803],"genre_scores_gemma":[0.9942227,0.0009708742,0.0026599176,0.000039990224,0.000017895893,0.00002162314,0.00019931067,0.0000131964225,0.0018545245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996742,0.000093107206,0.00001958412,0.0000482289,0.00008211206,0.00008281363],"domain_scores_gemma":[0.99966955,0.00014078761,0.00006622336,0.00003310712,0.00006579066,0.000024508045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000383039,0.0003243131,0.00029626256,0.00014049324,0.00023487165,0.00030156106,0.00031516966,0.00037196992,0.00153082],"category_scores_gemma":[0.00033349684,0.00024524808,0.00037019828,0.00024126614,0.00026389293,0.00043914162,0.00015414113,0.00063134695,0.00023335268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035639037,0.000035290755,0.00018124898,0.000046749934,0.000013288985,0.000040310304,0.000041287058,0.000099200945,0.9985285,0.00004271147,0.00001719342,0.0005977299],"study_design_scores_gemma":[0.000008467841,0.000292091,0.0029257943,0.0000031268123,0.000025339394,0.000082456274,0.00007747061,0.0011812977,0.9949115,0.000024687482,0.00046135733,0.000006446389],"about_ca_topic_score_codex":0.0016314471,"about_ca_topic_score_gemma":0.0016245177,"teacher_disagreement_score":0.0016314471,"about_ca_system_score_codex":0.00020664324,"about_ca_system_score_gemma":0.0001850404,"threshold_uncertainty_score":0.005121112},"labels":[],"label_agreement":null},{"id":"W2035828885","doi":"10.1007/s11095-006-9900-x","title":"Role of Phospholipid Transfer Protein on the Plasma Distribution of Amphotericin B Following the Incubation of Different Amphotericin B Formulations","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Amphotericin B; Phospholipid; Pharmacokinetics; Pharmacology; Chemistry; Phospholipid transfer protein; Medicine; Microbiology; Biochemistry; Biology; Antifungal; Membrane","score_opus":0.06379976497180923,"score_gpt":0.3910959752000902,"score_spread":0.327296210228281,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035828885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99437606,0.0011047741,0.0025677104,0.00011742843,0.000035142424,0.000019996109,0.00017479407,0.000026926547,0.0015772447],"genre_scores_gemma":[0.9957789,0.00049839105,0.001495106,0.000055811903,0.000017942324,0.000026772612,0.00022763797,0.00002319895,0.0018761909],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997429,0.00008425504,0.000016875194,0.000040620052,0.000039087663,0.0000761605],"domain_scores_gemma":[0.99964345,0.00017190156,0.00005460949,0.000027736305,0.000065969376,0.000036311107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003968388,0.00030583577,0.00028784634,0.0001436011,0.00026958066,0.00061850116,0.00022045834,0.00041855362,0.0019045434],"category_scores_gemma":[0.00070099335,0.00021460046,0.00021179285,0.00017040921,0.00049854704,0.00062696903,0.00020957174,0.00066590984,0.00047210773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010278914,0.00002802796,0.00021977832,0.000046254383,0.000011617006,0.00011403459,0.000088316985,0.00005634204,0.99687827,0.00011347049,0.000037701,0.0013781899],"study_design_scores_gemma":[0.000027001364,0.00026251096,0.0037622242,0.000008943132,0.00002614273,0.00015789559,0.0000803572,0.0011173838,0.9937935,0.00006093603,0.00069382886,0.000009236095],"about_ca_topic_score_codex":0.0009812734,"about_ca_topic_score_gemma":0.0006634194,"teacher_disagreement_score":0.0019045434,"about_ca_system_score_codex":0.00029088932,"about_ca_system_score_gemma":0.0003060776,"threshold_uncertainty_score":0.0063713193},"labels":[],"label_agreement":null},{"id":"W2035882594","doi":"10.1007/s11095-014-1423-2","title":"Controlled Delivery of Fibroblast Growth Factor-9 from Biodegradable Poly(ester amide) Fibers for Building Functional Neovasculature","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"FGF9; Fibroblast growth factor; Cell biology; Growth factor; Angiogenesis; Fibroblast; Chemistry; Electrospinning; Biomedical engineering; Biophysics; In vitro; Biochemistry; Biology; Receptor; Cancer research; Medicine","score_opus":0.08117541747311194,"score_gpt":0.38527091993228313,"score_spread":0.30409550245917116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035882594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838218,0.0012982748,0.011941396,0.00007965058,0.00004985575,0.000039220402,0.00015407732,0.000086505905,0.0025291604],"genre_scores_gemma":[0.9890297,0.0007463354,0.0077130958,0.000029056762,0.000017857632,0.000030885072,0.00008068406,0.000020315863,0.0023320692],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999946,0.0000057082084,0.000004345733,0.000015700263,0.000015496173,0.00001279845],"domain_scores_gemma":[0.9999368,0.000012766699,0.000026575295,0.0000038045596,0.000008217472,0.000011802584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014684866,0.00026475103,0.00008176058,0.00011619591,0.000106999534,0.00018617464,0.00012336316,0.000246748,0.00049558695],"category_scores_gemma":[0.00010953355,0.00009527826,0.00014156231,0.00006373061,0.00011965014,0.00032880143,0.00011652956,0.00022787096,0.0001436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023714369,0.000008073757,0.000021217342,0.000015347972,0.0000011659148,0.000030388177,0.0000055099,0.00009436528,0.99860954,0.000070149865,0.000017445187,0.0011030377],"study_design_scores_gemma":[0.0000057809466,0.00006001767,0.0002539737,0.0000015270347,0.0000026564585,0.00004177843,0.000003259644,0.0006552855,0.99825305,0.00001965667,0.0007002555,0.0000026868213],"about_ca_topic_score_codex":0.00050075195,"about_ca_topic_score_gemma":0.0009263689,"teacher_disagreement_score":0.00050075195,"about_ca_system_score_codex":0.00022269032,"about_ca_system_score_gemma":0.0001473608,"threshold_uncertainty_score":0.0016579032},"labels":[],"label_agreement":null},{"id":"W2037970310","doi":"10.1023/b:pham.0000041449.46054.b4","title":"Heat-Treated Fungizone Retains Amphotericin B Antifungal Activity Without Renal Toxicity in Rats Infected with Aspergillus Fumigatus","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Centers for Disease Control and Prevention; Michael Smith Health Research BC","keywords":"Aspergillus fumigatus; Amphotericin B; Creatinine; Toxicity; Pharmacology; Aspergillosis; Medicine; Kidney; Aspergillus; Biology; Antifungal; Internal medicine; Microbiology; Immunology","score_opus":0.10999938197175392,"score_gpt":0.43533573738627446,"score_spread":0.32533635541452055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037970310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977335,0.0007388464,0.0007997616,0.000054527976,0.000028500608,0.000009225953,0.00018592532,0.000067794914,0.0003819188],"genre_scores_gemma":[0.99760604,0.00035916892,0.000609299,0.000015315072,0.000013000349,0.000008311594,0.00019191358,0.000012048,0.0011849343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998573,0.00001669532,0.0000091107895,0.000026347536,0.000027377984,0.00006311712],"domain_scores_gemma":[0.99969816,0.000057260633,0.00008832448,0.00005098814,0.000027063772,0.00007825675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016244866,0.00039807265,0.00037580347,0.00056045805,0.000241702,0.00026976294,0.00031614924,0.0003971357,0.0011089626],"category_scores_gemma":[0.0002159029,0.00031306827,0.00028376622,0.0002247575,0.00058871036,0.00045723375,0.0001410386,0.00071014406,0.0002856342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020467865,0.000118819036,0.0004018914,0.000026122769,0.0000065218164,0.00006361362,0.000029992578,0.000050528342,0.9959292,0.000083658895,0.00003519624,0.0012077268],"study_design_scores_gemma":[0.000032946693,0.0011912797,0.0038317593,0.0000031051738,0.000023770343,0.00013428714,0.000035727982,0.00030301753,0.9940848,0.000041891755,0.0003109966,0.0000064880587],"about_ca_topic_score_codex":0.0022639849,"about_ca_topic_score_gemma":0.0021066011,"teacher_disagreement_score":0.0022639849,"about_ca_system_score_codex":0.00021877208,"about_ca_system_score_gemma":0.00033841198,"threshold_uncertainty_score":0.004501581},"labels":[],"label_agreement":null},{"id":"W2037992064","doi":"10.1007/s11095-013-1237-7","title":"Synthesis, Characterization and Biodistribution Studies of 125I-Radioiodinated di-PEGylated Bone Targeting Salmon Calcitonin Analogue in Healthy Rats","year":2013,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Bone health and treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"PEGylation; Chemistry; Biodistribution; Pharmacokinetics; PEG ratio; Pharmacology; Calcitonin; Bone mineral; Bone disease; Internal medicine; Osteoporosis; Medicine; Biochemistry; Polyethylene glycol; In vitro","score_opus":0.1978690741316341,"score_gpt":0.4899898598532508,"score_spread":0.2921207857216167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037992064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923253,0.0007151139,0.005743721,0.000030685376,0.000017603561,0.00004262226,0.00026401755,0.00006869822,0.0007921815],"genre_scores_gemma":[0.9876652,0.0007257265,0.005459775,0.000036424157,0.0000093671215,0.000037719845,0.0005028109,0.000037905993,0.005524961],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999944,0.000004159933,0.0000042540933,0.00001884876,0.000014639584,0.000014054255],"domain_scores_gemma":[0.99987817,0.00001846342,0.000043687476,0.000014330617,0.00002126331,0.000024054443],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014426,0.0002651289,0.00017274475,0.0002074922,0.00012138923,0.00010795883,0.00017703779,0.00019143695,0.0007957856],"category_scores_gemma":[0.000121887875,0.00012631128,0.00019219267,0.00014371905,0.0001912071,0.0001866832,0.00007474416,0.00018350546,0.0002188382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022856591,0.000021118125,0.000087183624,0.000019191688,0.0000021734475,0.00003502044,0.000011210971,0.0001056551,0.99850595,0.00003610049,0.000010138668,0.0009377308],"study_design_scores_gemma":[0.000016986993,0.0008875809,0.001223571,0.0000013453351,0.000020778707,0.00012710075,0.000017519567,0.00043969756,0.9965424,0.000021491434,0.0006952913,0.000006249487],"about_ca_topic_score_codex":0.0013524031,"about_ca_topic_score_gemma":0.0011297168,"teacher_disagreement_score":0.0013524031,"about_ca_system_score_codex":0.00013251929,"about_ca_system_score_gemma":0.0001832217,"threshold_uncertainty_score":0.0026891232},"labels":[],"label_agreement":null},{"id":"W2040238800","doi":"10.1007/s11095-012-0837-y","title":"Magnetic Resonance Microscopy for Assessment of Morphological Changes in Hydrating Hydroxypropylmethyl Cellulose Matrix Tablets In Situ","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; National Research Council Institute for Biodiagnostics","funders":"","keywords":"Relaxometry; In situ; Matrix (chemical analysis); Excipient; Materials science; Dosage form; Magnetic resonance imaging; Nuclear magnetic resonance; Spin echo; Chemistry; Chromatography; Composite material; Physics","score_opus":0.34803358035269905,"score_gpt":0.576297430899428,"score_spread":0.22826385054672893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040238800","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.899298,0.006603476,0.09087859,0.00010450698,0.00006207051,0.00013967918,0.000339486,0.00030099403,0.0022731316],"genre_scores_gemma":[0.8977806,0.004142772,0.09497462,0.0001059142,0.000034508663,0.00016361629,0.0003114653,0.00005832605,0.002428297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998944,0.000019217367,0.0000066867974,0.00003094174,0.000037592847,0.00001120707],"domain_scores_gemma":[0.99978215,0.000077217825,0.000052753734,0.000022134545,0.000047717014,0.00001804754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027015418,0.00030710764,0.00014003129,0.00030648054,0.00010332564,0.00016610403,0.00014700866,0.00037705156,0.0008632993],"category_scores_gemma":[0.00035799696,0.0001538655,0.00012320974,0.00014224781,0.0001934093,0.00023288658,0.00013367584,0.00036749162,0.00023658924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018285204,0.0000042598886,0.00006481653,0.000023368246,0.0000014909558,0.000013229957,0.0000062381114,0.000020006915,0.99876934,0.000011603589,0.0000051796064,0.0010620675],"study_design_scores_gemma":[0.0000049204064,0.00018997284,0.005928225,0.0000075138364,0.000016801241,0.00027463996,0.000022077993,0.0015140742,0.9913203,0.000019837144,0.00069626997,0.00000533993],"about_ca_topic_score_codex":0.00041699188,"about_ca_topic_score_gemma":0.00064382394,"teacher_disagreement_score":0.0008632993,"about_ca_system_score_codex":0.0001300012,"about_ca_system_score_gemma":0.000119926786,"threshold_uncertainty_score":0.0028880835},"labels":[],"label_agreement":null},{"id":"W2041543868","doi":"10.1007/s11095-014-1503-3","title":"Stimulation and Suppression of Innate Immune Function by American Ginseng Polysaccharides: Biological Relevance and Identification of Bioactives","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Proinflammatory cytokine; In vivo; Immune system; Pharmacology; Ex vivo; Lipopolysaccharide; Alveolar macrophage; Innate immune system; Tumor necrosis factor alpha; Chemistry; Ginseng; Cytokine; Immunology; Macrophage; In vitro; Biology; Inflammation; Biochemistry; Medicine","score_opus":0.056216823215967694,"score_gpt":0.4136649305487168,"score_spread":0.35744810733274907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041543868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922989,0.004058517,0.0019438274,0.00017155948,0.000031345342,0.000019394358,0.00007675675,0.000012526896,0.0013871791],"genre_scores_gemma":[0.9963756,0.0017270443,0.00094217557,0.00005912197,0.000026842104,0.000010518478,0.00009565915,0.0000035016767,0.00075950753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999347,0.000018216691,0.000004822203,0.00000929488,0.000013504021,0.000019533109],"domain_scores_gemma":[0.9999349,0.00001528777,0.000014886336,0.00000940547,0.000010201794,0.000015197701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001655615,0.00034430443,0.00015309089,0.00021461357,0.00013878533,0.00026277118,0.000091591675,0.00017020997,0.0004439047],"category_scores_gemma":[0.000107083346,0.00008567177,0.00028187735,0.00019383835,0.00028876445,0.00023279402,0.00017043897,0.00040411882,0.000097010634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039301495,0.000037889113,0.0004904439,0.00003276013,0.000005618694,0.000074101335,0.000012499796,0.000038497084,0.99578756,0.00024269843,0.0000146145085,0.0028703124],"study_design_scores_gemma":[0.00003396815,0.0004197222,0.01186714,0.000007725712,0.000027042386,0.00023495583,0.000055906086,0.00032942797,0.9853489,0.000264796,0.0014069132,0.0000036550662],"about_ca_topic_score_codex":0.00024728637,"about_ca_topic_score_gemma":0.00029524186,"teacher_disagreement_score":0.0004439047,"about_ca_system_score_codex":0.00014391281,"about_ca_system_score_gemma":0.00021359205,"threshold_uncertainty_score":0.0014849901},"labels":[],"label_agreement":null},{"id":"W2041891427","doi":"10.1007/s11095-008-9751-8","title":"Movement of Heparins Across Rat Gastric Mucosa is Dependent on Molecular Weight and pH","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Gastric mucosa; Chemistry; Pharmacology; Gastroenterology; Biochemistry; Medicine; Stomach","score_opus":0.09976014725276142,"score_gpt":0.43859173697581666,"score_spread":0.33883158972305527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041891427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941678,0.0022357663,0.0020712903,0.00012845697,0.000025613694,0.000017957733,0.00010964603,0.000046145604,0.0011973792],"genre_scores_gemma":[0.9924535,0.0015512136,0.0028439066,0.00005750418,0.00003134709,0.000015742777,0.00024474366,0.000038586455,0.0027635074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984896,0.000027689015,0.000010226944,0.0000316827,0.000027980104,0.00005342325],"domain_scores_gemma":[0.999665,0.00010061149,0.00008460436,0.00003704242,0.00003799217,0.000074706106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029308826,0.00039232013,0.00037676448,0.0004104993,0.00020618721,0.0004592135,0.00034495033,0.00031088456,0.0013645107],"category_scores_gemma":[0.00030150468,0.0005066004,0.0004856664,0.00024610705,0.00050779944,0.0006968689,0.0002497268,0.00056948327,0.00037367127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014572848,0.00001940018,0.00051875063,0.000051845782,0.000013555514,0.0000452392,0.000044847995,0.00008376016,0.99427176,0.00019105632,0.00002549223,0.0032771218],"study_design_scores_gemma":[0.000058520465,0.0008800253,0.012764102,0.000011389633,0.00004375459,0.00015729743,0.0000869696,0.0015057792,0.98362166,0.00014791616,0.0007080946,0.000014533524],"about_ca_topic_score_codex":0.0021776585,"about_ca_topic_score_gemma":0.0019659083,"teacher_disagreement_score":0.0021776585,"about_ca_system_score_codex":0.0004966557,"about_ca_system_score_gemma":0.00040157366,"threshold_uncertainty_score":0.0045647025},"labels":[],"label_agreement":null},{"id":"W2042233059","doi":"10.1007/s11095-011-0480-z","title":"siRNA-Mediated Down-Regulation of P-glycoprotein in a Xenograft Tumor Model in NOD-SCID Mice","year":2011,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; University of Alberta","funders":"Canadian Institutes of Health Research; Ministry of Advanced Education, Government of Alberta","keywords":"Small interfering RNA; Doxorubicin; P-glycoprotein; Cancer research; Pharmacology; Gene silencing; Nod; Chemistry; In vitro; Medicine; Transfection; In vivo; Chemotherapy; Biology; Internal medicine; Multiple drug resistance; Biochemistry","score_opus":0.23549715314406358,"score_gpt":0.43309423225621924,"score_spread":0.19759707911215565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042233059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98390824,0.0017867234,0.0069690263,0.00078287645,0.00028711386,0.00021072611,0.0021560662,0.0005819783,0.0033171733],"genre_scores_gemma":[0.9803531,0.0015858848,0.0054934635,0.00019960536,0.00007447442,0.00036310044,0.0019531737,0.00013330624,0.009843895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954,0.00007181366,0.00006010554,0.00012372603,0.00009472029,0.00010969383],"domain_scores_gemma":[0.9996908,0.00006155051,0.00010831934,0.000040697076,0.000028641833,0.00007011707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048184374,0.00087244896,0.00070838485,0.00084447826,0.00035580527,0.000584035,0.00050500414,0.0009232312,0.0020157786],"category_scores_gemma":[0.00019551878,0.00044142373,0.0007745606,0.0004503409,0.00066427607,0.00067239575,0.00024087104,0.0017847874,0.00077833625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000570549,0.00014709546,0.00006883583,0.000045236295,0.000013195835,0.000057826324,0.000021742895,0.00011322535,0.99792105,0.00020102918,0.00016527761,0.00067496405],"study_design_scores_gemma":[0.00013451767,0.00074556563,0.00076644076,0.000005487465,0.000047945097,0.00018080698,0.00002506473,0.0016149483,0.99486405,0.00006615067,0.0015405469,0.000008474636],"about_ca_topic_score_codex":0.0015330147,"about_ca_topic_score_gemma":0.0017040735,"teacher_disagreement_score":0.0020157786,"about_ca_system_score_codex":0.00056361675,"about_ca_system_score_gemma":0.00049859384,"threshold_uncertainty_score":0.006743431},"labels":[],"label_agreement":null},{"id":"W2044417463","doi":"10.1007/s11095-006-9750-6","title":"Osmotic-Driven Release Kinetics of Bioactive Therapeutic Proteins from a Biodegradable Elastomer are Linear, Constant, Similar, and Adjustable","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Hydrogels: synthesis, properties, applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Kinetics; Elastomer; Constant (computer programming); Chemistry; Pharmaceutical technology; Materials science; Chemical engineering; Polymer science; Chromatography; Composite material; Physics; Computer science; Engineering","score_opus":0.08773406909460144,"score_gpt":0.36889064790968046,"score_spread":0.28115657881507905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044417463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9847415,0.0008682935,0.012186913,0.00012793046,0.00004227902,0.000022875416,0.00024154216,0.00015205961,0.001616575],"genre_scores_gemma":[0.9923409,0.00043865916,0.0043489947,0.00006907481,0.00001684146,0.000027415494,0.00014209042,0.000048350095,0.0025676193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998833,0.000011039966,0.000007985561,0.00003032112,0.000041865977,0.000025456018],"domain_scores_gemma":[0.99971336,0.000093598464,0.00011181541,0.00002042224,0.00002599718,0.0000348618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025314552,0.00028803773,0.00013358398,0.00012840256,0.00009949132,0.00036640422,0.00019842132,0.00023159807,0.0010747699],"category_scores_gemma":[0.00047448574,0.00021404546,0.00020539958,0.00010461718,0.00030430968,0.00043797438,0.0001451868,0.00052293786,0.00033184286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008312378,0.000013921867,0.00007920108,0.000016862015,0.0000026280488,0.00001681968,0.000017781816,0.000118970675,0.99785185,0.00023484684,0.0000412679,0.0015227383],"study_design_scores_gemma":[0.000011437523,0.00005386696,0.00050114613,0.0000019943827,0.000004269784,0.000043502023,0.00000451257,0.0019395538,0.99683654,0.00004523909,0.0005500404,0.000007873085],"about_ca_topic_score_codex":0.00021791768,"about_ca_topic_score_gemma":0.0003322072,"teacher_disagreement_score":0.0010747699,"about_ca_system_score_codex":0.00032695747,"about_ca_system_score_gemma":0.00018063893,"threshold_uncertainty_score":0.0035954118},"labels":[],"label_agreement":null},{"id":"W2046783680","doi":"10.1007/s11095-005-7248-2","title":"Membrane Binding Proteins are the Major Determinants for the Hepatocellular Transmembrane Flux of Long-Chain Fatty Acids Bound to Albumin","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Health and Medical Research Council; Canadian Institutes of Health Research; University of Queensland; National Medical Research Council; University of Manitoba","keywords":"Hepatocyte; Chemistry; Bovine serum albumin; Antiserum; Albumin; Fatty acid-binding protein; Biochemistry; Fatty acid; Serum albumin; Cytosol; Binding protein; Chromatography; Biology; In vitro; Antibody; Enzyme","score_opus":0.09418532901108659,"score_gpt":0.4071504583204645,"score_spread":0.3129651293093779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046783680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9708133,0.004192033,0.020272475,0.0007153481,0.00006512189,0.000048457743,0.00043462872,0.00021807078,0.0032405928],"genre_scores_gemma":[0.9866876,0.0010364598,0.004990444,0.00015020915,0.000036797872,0.000022238706,0.000807639,0.00007284222,0.0061957613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997032,0.00009369887,0.000014771321,0.000040217375,0.00007180299,0.00007613569],"domain_scores_gemma":[0.9996449,0.00009658914,0.00006517038,0.000025588546,0.000087935936,0.00007981682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032756588,0.00037815687,0.00048805968,0.0004447109,0.00031374686,0.00070303417,0.00027513297,0.0004983214,0.0036608097],"category_scores_gemma":[0.00066822703,0.00032120832,0.00039627778,0.00030330603,0.00023350559,0.000542124,0.00031210567,0.0006203647,0.0017344756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004815702,0.000013402954,0.000787141,0.000046085515,0.000014409554,0.0000736075,0.000028517208,0.00006142248,0.9958072,0.000591063,0.00011420228,0.001981429],"study_design_scores_gemma":[0.00004148298,0.00012745758,0.031368103,0.00001734229,0.000056044206,0.0006356879,0.00018864678,0.005592027,0.9558697,0.0007713376,0.0053022816,0.000029848823],"about_ca_topic_score_codex":0.0015251546,"about_ca_topic_score_gemma":0.0010360798,"teacher_disagreement_score":0.0036608097,"about_ca_system_score_codex":0.00059413636,"about_ca_system_score_gemma":0.00016445386,"threshold_uncertainty_score":0.012246609},"labels":[],"label_agreement":null},{"id":"W2048411496","doi":"10.1007/s11095-011-0478-6","title":"Assessment of P-glycoprotein Activity in the Blood-Brain Barrier (BBB) Using Near Infrared Fluorescence (NIRF) Imaging Techniques","year":2011,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Research Manitoba; Manitoba Health Research Council","keywords":"Blood–brain barrier; P-glycoprotein; In vivo; Chemistry; Rhodamine 123; Ex vivo; Fluorescence; Biophysics; Pharmacology; In vitro; Biology; Central nervous system; Biochemistry; Endocrinology","score_opus":0.19484357758906073,"score_gpt":0.4801592785353173,"score_spread":0.2853157009462566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048411496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8917149,0.010615806,0.08884713,0.00055558694,0.00004850573,0.00008764486,0.0005259354,0.00027567515,0.0073289513],"genre_scores_gemma":[0.9243589,0.00917293,0.059506383,0.00018703284,0.000063157095,0.00014132258,0.0003883661,0.000062573876,0.006119278],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982613,0.000047838494,0.0000066873226,0.0000349306,0.000047755897,0.00003670921],"domain_scores_gemma":[0.9998228,0.00007089688,0.000034472636,0.000010363619,0.000041837386,0.000019688876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003525989,0.00034345305,0.0002868076,0.000470633,0.00034825882,0.00046937633,0.00021075601,0.0006427994,0.00073840603],"category_scores_gemma":[0.00040549453,0.00019352071,0.0001922066,0.0002767607,0.00028333932,0.0011348746,0.00018129325,0.00095442706,0.00026805443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011643519,0.000022935103,0.00035683575,0.000051322364,0.000005390654,0.00005514731,0.000025939527,0.000046316793,0.9955035,0.00019033435,0.00006828194,0.0035576136],"study_design_scores_gemma":[0.000011679483,0.0002974182,0.009960051,0.000011700442,0.000030888004,0.00065244304,0.000083375264,0.0031717774,0.9833467,0.00027793716,0.002141832,0.000014321769],"about_ca_topic_score_codex":0.0020813597,"about_ca_topic_score_gemma":0.0017723688,"teacher_disagreement_score":0.0020813597,"about_ca_system_score_codex":0.0002829236,"about_ca_system_score_gemma":0.00030217608,"threshold_uncertainty_score":0.00413841},"labels":[],"label_agreement":null},{"id":"W2048416027","doi":"10.1023/b:pham.0000022419.18144.9e","title":"Spinal Disposition and Meningeal Permeability of Local Anesthetics","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Cerebrospinal fluid and hydrocephalus","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Microdialysis; Bioavailability; Meninges; Lipophilicity; Cerebrospinal fluid; In vivo; Pharmacology; Pharmacokinetics; Chemistry; Anesthesia; Dura mater; Ex vivo; Epidural space; Permeability (electromagnetism); Medicine; Extracellular; Pathology; Surgery; In vitro; Biochemistry","score_opus":0.18654423100173922,"score_gpt":0.46996428998498213,"score_spread":0.2834200589832429,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048416027","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925524,0.0042331996,0.00078916905,0.00021622324,0.000023633844,0.000018725228,0.00008797014,0.000018154426,0.0020605726],"genre_scores_gemma":[0.9960691,0.0021180518,0.00046759733,0.000078768404,0.000042210493,0.000010888793,0.00008047402,0.000012999869,0.0011199937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997552,0.000118284894,0.000012680166,0.000026606855,0.000036334153,0.00005094633],"domain_scores_gemma":[0.9989404,0.00036142973,0.00037116246,0.00008188786,0.00010329683,0.00014182781],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004440052,0.00022513949,0.0003160597,0.0004060508,0.00037810154,0.001250419,0.00031021837,0.0005762604,0.0031588583],"category_scores_gemma":[0.0023466037,0.0003349252,0.00027873562,0.00030896664,0.0007296601,0.0018604846,0.00024546543,0.00090556,0.00046115398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.13468096,0.0015984201,0.05271047,0.00082096126,0.00083691423,0.005186604,0.0017184216,0.0029265648,0.6527873,0.018746937,0.0024225125,0.12556393],"study_design_scores_gemma":[0.0010162466,0.014801902,0.40979084,0.0001242142,0.000932937,0.010518248,0.0024778624,0.016643913,0.5248508,0.008697328,0.009990179,0.00015553289],"about_ca_topic_score_codex":0.0036599957,"about_ca_topic_score_gemma":0.0026932599,"teacher_disagreement_score":0.0036599957,"about_ca_system_score_codex":0.0008907044,"about_ca_system_score_gemma":0.0008338411,"threshold_uncertainty_score":0.010567486},"labels":[],"label_agreement":null},{"id":"W2050393309","doi":"10.1007/s11095-008-9796-8","title":"Pharmacogenomics Approach Reveals MRP1 (ABCC1)-Mediated Resistance to Geldanamycins","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"Geldanamycin; ABCC1; Efflux; Multiple drug resistance; P-glycoprotein; Biology; ATP-binding cassette transporter; Transporter; Hsp90; Intracellular; Cytotoxicity; Heat shock protein; Cell culture; Drug resistance; Multidrug Resistance-Associated Proteins; Multidrug resistance-associated protein 2; Daunorubicin; Cell biology; Gene; Biochemistry; In vitro; Genetics","score_opus":0.2495292053185722,"score_gpt":0.4553199251489245,"score_spread":0.2057907198303523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050393309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900755,0.00043509132,0.006595509,0.0004819362,0.000022803242,0.000024010375,0.00060754764,0.00015070492,0.0016069713],"genre_scores_gemma":[0.9920481,0.00040310042,0.0043348456,0.00013424596,0.000010097554,0.000022351485,0.00073871063,0.00004817145,0.0022604503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986124,0.000033109493,0.0000066396037,0.000027021477,0.000034491517,0.000037525126],"domain_scores_gemma":[0.9999131,0.00003067565,0.00001984229,0.000012039697,0.000015000245,0.000009400935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013016345,0.0002996172,0.00036259092,0.00036228116,0.00016327825,0.00031355215,0.00026607676,0.0004462975,0.0011742908],"category_scores_gemma":[0.00024691602,0.00019922871,0.0003368197,0.00020181919,0.00021450392,0.0001622202,0.00014468512,0.0007194562,0.00046135203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009437984,0.000016532196,0.00016972405,0.000009704959,0.000005083602,0.00003960327,0.000005394755,0.00009749983,0.9987218,0.0000794192,0.00004703032,0.00071375753],"study_design_scores_gemma":[0.0000069836933,0.000082786864,0.0034212582,0.0000013630801,0.000016240856,0.00023495895,0.0000146974035,0.0018730595,0.99363685,0.000055512293,0.0006528446,0.0000034678578],"about_ca_topic_score_codex":0.000819697,"about_ca_topic_score_gemma":0.00079559913,"teacher_disagreement_score":0.0011742908,"about_ca_system_score_codex":0.00034577993,"about_ca_system_score_gemma":0.00014950987,"threshold_uncertainty_score":0.003928423},"labels":[],"label_agreement":null},{"id":"W2053276138","doi":"10.1007/s11095-006-9662-5","title":"Long Circulating Poly(Ethylene Glycol)-Decorated Lipid Nanocapsules Deliver Docetaxel to Solid Tumors","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Micropharma (Canada); Université de Montréal; Université du Québec à Montréal","funders":"Canada Research Chairs","keywords":"Nanocapsules; Docetaxel; Biodistribution; Ethylene glycol; Pharmacokinetics; Polyethylene glycol; Drug carrier; Chemistry; In vivo; Pharmacology; Drug delivery; Materials science; Nanoparticle; Medicine; Organic chemistry; Biochemistry; Nanotechnology; In vitro; Chemotherapy; Surgery","score_opus":0.09720313029202197,"score_gpt":0.4173407567846074,"score_spread":0.3201376264925854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053276138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848087,0.0039957482,0.008432009,0.00025386616,0.000075939875,0.00003845665,0.00009965064,0.00012390173,0.0021717453],"genre_scores_gemma":[0.99051267,0.0010220225,0.003203075,0.0000768466,0.000014568459,0.000016748152,0.00005371259,0.000026142,0.0050741713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999951,0.0000060322113,0.0000027749509,0.00001341063,0.000010075028,0.00001673184],"domain_scores_gemma":[0.9999492,0.000014000378,0.0000119527485,0.00000460436,0.00000593744,0.000014332265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013524349,0.00017838216,0.00016208582,0.00010248009,0.0001352965,0.0003433797,0.00013007697,0.00025314384,0.0008505961],"category_scores_gemma":[0.00013193589,0.00013367941,0.00011928491,0.00008153798,0.00019537697,0.00035825337,0.0001499509,0.00036597063,0.00040976214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016127131,0.000026690905,0.00009483409,0.000035569163,0.0000044747585,0.00006348149,0.000030612922,0.00030972375,0.9941222,0.00030140168,0.00011303705,0.0047366857],"study_design_scores_gemma":[0.0000414859,0.00025376212,0.00059970765,0.0000045722372,0.000017181403,0.000086262415,0.000016267088,0.0010115528,0.99435556,0.00006245203,0.003546124,0.0000051851507],"about_ca_topic_score_codex":0.00073489075,"about_ca_topic_score_gemma":0.0017740839,"teacher_disagreement_score":0.0008505961,"about_ca_system_score_codex":0.0005281664,"about_ca_system_score_gemma":0.00031474448,"threshold_uncertainty_score":0.0038321614},"labels":[],"label_agreement":null},{"id":"W2053834434","doi":"10.1007/s11095-012-0784-7","title":"Physiologically Based Pharmacokinetic Model for Composite Nanodevices: Effect of Charge and Size on In Vivo Disposition","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Dendrimers and Hyperbranched Polymers","field":"Materials Science","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health; University of Michigan; Eli Lilly and Company","keywords":"Physiologically based pharmacokinetic modelling; Pharmacokinetics; In vivo; Mononuclear phagocyte system; Nanoparticle; Chemistry; Biophysics; Particle size; Nanomedicine; Nanotechnology; Materials science; Pharmacology; Biology; Immunology; Physical chemistry","score_opus":0.1101902823953732,"score_gpt":0.44855104693494746,"score_spread":0.33836076453957425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053834434","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23737031,0.004328502,0.74735767,0.001087754,0.00018129095,0.00021999914,0.0007907261,0.0005300807,0.008133688],"genre_scores_gemma":[0.9453379,0.0032987616,0.03275287,0.00047680872,0.000062086925,0.0005023119,0.00043654253,0.00015412924,0.016978538],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9998814,0.000024183746,0.0000057972834,0.0000409189,0.00002816725,0.000019528119],"domain_scores_gemma":[0.99975973,0.000140521,0.000041257867,0.000011402938,0.000036826757,0.000010322111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031537467,0.00077032583,0.0007989343,0.00033452152,0.00017758369,0.0007089478,0.0006984007,0.0011477765,0.0007867395],"category_scores_gemma":[0.00084414636,0.00033733674,0.0007885213,0.00024868207,0.00037847838,0.000679026,0.00025983242,0.0007496718,0.00053974194],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003750866,0.00010032904,0.0006318607,0.000308011,0.00007925607,0.0004592636,0.00010105289,0.7913026,0.18390322,0.010881837,0.0008920467,0.01096538],"study_design_scores_gemma":[0.000019778003,0.00010607245,0.0002631585,0.000009745732,0.00004167936,0.00015228732,0.000009865221,0.978784,0.018368697,0.0012445414,0.0009835954,0.0000164998],"about_ca_topic_score_codex":0.0015732005,"about_ca_topic_score_gemma":0.0007553592,"teacher_disagreement_score":0.0015732005,"about_ca_system_score_codex":0.00079931965,"about_ca_system_score_gemma":0.0006317701,"threshold_uncertainty_score":0.0057994723},"labels":[],"label_agreement":null},{"id":"W2053867184","doi":"10.1023/b:pham.0000041459.63362.6f","title":"Assessment of the Potential Skin Irritation of Lysine-Derivative Anionic Surfactants Using Mouse Fibroblasts and Human Keratinocytes as An Alternative to Animal Testing","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institute of Steel Construction","keywords":"Sodium dodecyl sulfate; Chemistry; Counterion; Keratinocyte; Cytotoxicity; In vivo; Pulmonary surfactant; Irritation; Cationic polymerization; Sodium; Chromatography; In vitro; Biochemistry; Organic chemistry; Ion; Biology","score_opus":0.33879820332926197,"score_gpt":0.5854334552730868,"score_spread":0.2466352519438248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053867184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98667496,0.001604097,0.00903791,0.00006576189,0.000058791873,0.00013544362,0.00022005395,0.00003548105,0.0021674607],"genre_scores_gemma":[0.98975897,0.0013168786,0.00586585,0.000046345016,0.000011786458,0.00009828284,0.00027502686,0.000011403048,0.0026154201],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949026,0.00020189252,0.000058480604,0.0000670417,0.00012237392,0.000059862807],"domain_scores_gemma":[0.9994802,0.0002354981,0.000062903455,0.000081556194,0.000112877766,0.000026985046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008813047,0.0006245638,0.00023990405,0.00027525917,0.00026115048,0.00028283786,0.00024101164,0.0006382585,0.0013848308],"category_scores_gemma":[0.0003968609,0.00016488046,0.0005081231,0.00026234984,0.00030138541,0.0003251524,0.00025460558,0.000490706,0.00025321115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093108414,0.00003585995,0.0001566739,0.00002243705,0.0000035274861,0.000046339173,0.00002273184,0.000030848005,0.99918395,0.000023374425,0.0000056835397,0.00037540283],"study_design_scores_gemma":[0.0000033691567,0.000679598,0.0009720473,0.0000019980373,0.000014162754,0.00008954108,0.000042214724,0.00018946124,0.99777395,0.00001193477,0.00021920846,0.000002565386],"about_ca_topic_score_codex":0.0010339346,"about_ca_topic_score_gemma":0.0012882953,"teacher_disagreement_score":0.0013848308,"about_ca_system_score_codex":0.00017103694,"about_ca_system_score_gemma":0.00024758317,"threshold_uncertainty_score":0.004660785},"labels":[],"label_agreement":null},{"id":"W2054403765","doi":"10.1007/s11095-012-0727-3","title":"Reversine, a 2,6-disubstituted Purine, as an Anti-cancer Agent in Differentiated and Undifferentiated Thyroid Cancer Cells","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ditmanson Medical Foundation Chia-Yi Christian Hospital; Beef Cattle Research Council; National Science Council","keywords":"Thyroid cancer; Cancer; Cancer cell; Cancer research; Purine; Medicine; Chemistry; Internal medicine; Biochemistry; Enzyme","score_opus":0.11688099918181656,"score_gpt":0.46838437334371386,"score_spread":0.3515033741618973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054403765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991109,0.0049854005,0.0008055084,0.000066963614,0.000052939347,0.00002906181,0.00037113577,0.00012011578,0.002459903],"genre_scores_gemma":[0.99218893,0.0024340525,0.0011746188,0.000029470913,0.000014271442,0.00001324951,0.0005341812,0.000024837833,0.0035864373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981016,0.00005931592,0.000023357912,0.000030214762,0.000041906897,0.000034988156],"domain_scores_gemma":[0.9998435,0.000052648353,0.000019599434,0.000028086433,0.000023289824,0.00003299165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002755183,0.00027219197,0.0004022457,0.00044569655,0.00019553743,0.00032559753,0.00043305688,0.00040475553,0.0010545106],"category_scores_gemma":[0.00018254545,0.00018211796,0.00031681513,0.00035949066,0.00023368999,0.00032226226,0.00012937767,0.0005195158,0.0002443029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006874229,0.00007807658,0.00021452033,0.00008221542,0.000011156176,0.00013236156,0.00006884256,0.00028175802,0.9938577,0.0002882343,0.000081459475,0.0042163846],"study_design_scores_gemma":[0.000026372916,0.00083456346,0.0012361768,0.0000033039935,0.000026237449,0.00012176224,0.000019746467,0.0004869672,0.9954489,0.000017363209,0.0017736157,0.0000049815408],"about_ca_topic_score_codex":0.0027263034,"about_ca_topic_score_gemma":0.0034548645,"teacher_disagreement_score":0.0027263034,"about_ca_system_score_codex":0.00035410182,"about_ca_system_score_gemma":0.00040664928,"threshold_uncertainty_score":0.0054209232},"labels":[],"label_agreement":null},{"id":"W2055407291","doi":"10.1007/s11095-007-9367-4","title":"Alginate/Chitosan Nanoparticles are Effective for Oral Insulin Delivery","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":613,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Insulin; Chitosan; Chemistry; Oral administration; Pharmacology; Nanoparticle; In vivo; Ionotropic effect; Dosage form; Confocal microscopy; Internal medicine; Medicine; Biochemistry; Materials science; Biology; Nanotechnology; Receptor","score_opus":0.36640230536649526,"score_gpt":0.592568817950768,"score_spread":0.22616651258427273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055407291","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9623229,0.016768774,0.011621352,0.00057406473,0.00029742005,0.00008428276,0.00019660815,0.00029048076,0.007844047],"genre_scores_gemma":[0.98256737,0.0031219667,0.0057662884,0.00020762142,0.0000423457,0.000021282522,0.00011653839,0.00006753614,0.008089044],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980026,0.000020452904,0.000019173052,0.000042627347,0.00007970219,0.000037702404],"domain_scores_gemma":[0.9998511,0.000027613152,0.000048566788,0.000013055327,0.00003506588,0.000024646248],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017463123,0.00035906886,0.00025534924,0.00023599919,0.00021106692,0.0005002002,0.00019993681,0.00045529986,0.0011958127],"category_scores_gemma":[0.00023247839,0.00020458647,0.0003763949,0.00016821062,0.00023147445,0.00039918264,0.00021845191,0.0005355148,0.000285714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001776656,0.000021052898,0.00011389667,0.00007451468,0.000009274505,0.000041668005,0.000010023695,0.000046597466,0.9923489,0.00011262847,0.000120079465,0.006923715],"study_design_scores_gemma":[0.000012670433,0.0001398911,0.001039735,0.0000052779646,0.000038672813,0.00015192019,0.000007059775,0.00041412766,0.9953816,0.00003149263,0.0027690756,0.0000085002],"about_ca_topic_score_codex":0.0016199619,"about_ca_topic_score_gemma":0.0022263222,"teacher_disagreement_score":0.0016199619,"about_ca_system_score_codex":0.0004947379,"about_ca_system_score_gemma":0.00030109048,"threshold_uncertainty_score":0.0040004253},"labels":[],"label_agreement":null},{"id":"W2058559312","doi":"10.1023/b:pham.0000036905.82914.8e","title":"Functional Expression and Localization of P-glycoprotein in the Central Nervous System: Relevance to the Pathogenesis and Treatment of Neurological Disorders","year":2004,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Pathogenesis; Central nervous system; P-glycoprotein; Nervous system; Phenotype; Epilepsy; Neurodegeneration; Neuroscience; microRNA; Biology; Medicine; Immunology; Bioinformatics; Disease; Drug resistance; Multiple drug resistance; Pathology; Genetics; Gene","score_opus":0.1606092534488033,"score_gpt":0.4280373273562122,"score_spread":0.26742807390740886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058559312","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028306473,0.9985927,0.00022386499,0.00018142977,0.00010757295,0.0000029509822,0.00001537719,0.000006257706,0.00058672513],"genre_scores_gemma":[0.0008608968,0.9982494,0.0002704202,0.00008123127,0.00008836932,0.0000030695473,0.000027368491,8.932482e-7,0.00041834754],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99981815,0.000025562564,0.000028575687,0.000035683486,0.0000758431,0.000016232725],"domain_scores_gemma":[0.9997222,0.00011360335,0.00005354669,0.000009579486,0.00007718331,0.00002392252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062167953,0.00090798,0.0017525435,0.0015454214,0.00021456527,0.0013443955,0.0009683412,0.0012259481,0.0013199225],"category_scores_gemma":[0.0005709572,0.0002580079,0.000351606,0.0023377647,0.0005953004,0.0014002322,0.00040740432,0.0014604228,0.0015136942],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017396129,0.00007900558,0.0003086278,0.0123269595,0.000086023836,0.0006920464,0.000058392783,0.00048623572,0.0099982545,0.003067725,0.015751451,0.9569712],"study_design_scores_gemma":[0.000043317275,0.00017643916,0.002008448,0.0019316048,0.00021943075,0.005145943,0.00010484756,0.00021128304,0.003621041,0.0020399957,0.9844654,0.00003226812],"about_ca_topic_score_codex":0.0010298456,"about_ca_topic_score_gemma":0.001479976,"teacher_disagreement_score":0.0017525435,"about_ca_system_score_codex":0.0006881095,"about_ca_system_score_gemma":0.0011022268,"threshold_uncertainty_score":0.0049926043},"labels":[],"label_agreement":null},{"id":"W2061174885","doi":"10.1023/b:pham.0000022407.05163.01","title":"Impact of Tether Length on Bone Mineral Affinity of Protein-Bisphosphonate Conjugates","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Bone health and treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"Killam Trusts","keywords":"Fetuin; Conjugate; Chemistry; In vitro; In vivo; Conjugated system; Bisphosphonate; Bone mineral; Ligand (biochemistry); Biophysics; Biochemistry; Stereochemistry; Osteoporosis; Receptor; Polymer; Organic chemistry; Biology; Glycoprotein","score_opus":0.20297712948510815,"score_gpt":0.5313607577799465,"score_spread":0.32838362829483836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061174885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99809915,0.00043908667,0.0005011097,0.000074204036,0.000017093513,0.000007874238,0.00006620906,0.0000145746635,0.0007806708],"genre_scores_gemma":[0.99793684,0.00024361204,0.00038882197,0.00005345958,0.000009156625,0.000009401727,0.00013316605,0.000020751857,0.0012047532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999676,0.0000997143,0.000025138379,0.00004510522,0.000062891784,0.00009108586],"domain_scores_gemma":[0.99912304,0.00055554305,0.00010117084,0.000041651783,0.00008442208,0.00009418763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052702887,0.00023747538,0.00029363812,0.00014985612,0.0002641119,0.0004772332,0.0003287823,0.00042898083,0.0052257646],"category_scores_gemma":[0.0012573196,0.00023426712,0.00019910756,0.0002008668,0.00030824577,0.0005885058,0.00032636232,0.00051871367,0.00069392746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033732906,0.00014661986,0.00041798293,0.00007636556,0.000029111452,0.00007984396,0.0000742497,0.0007619262,0.9919076,0.00026178703,0.00010506386,0.0027662935],"study_design_scores_gemma":[0.000072458024,0.0010345138,0.0014009257,0.0000073279107,0.000044710945,0.00006689045,0.000033582928,0.0013895233,0.99495643,0.000062381696,0.00091836805,0.000012878447],"about_ca_topic_score_codex":0.0010517957,"about_ca_topic_score_gemma":0.0016442202,"teacher_disagreement_score":0.0052257646,"about_ca_system_score_codex":0.00038994703,"about_ca_system_score_gemma":0.0003448093,"threshold_uncertainty_score":0.017481983},"labels":[],"label_agreement":null},{"id":"W2061954970","doi":"10.1007/s11095-012-0847-9","title":"Retina-Choroid-Sclera Permeability for Ophthalmic Drugs in the Vitreous to Blood Direction: Quantitative Assessment","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Polar surface area; Permeability (electromagnetism); Sclera; Pharmacokinetics; Chemistry; Drug; Partition coefficient; Drug delivery; Chromatography; Biomedical engineering; Materials science; Pharmacology; Ophthalmology; Medicine; Organic chemistry; Biochemistry; Membrane; Molecule","score_opus":0.30036692430399475,"score_gpt":0.5899228206317579,"score_spread":0.2895558963277632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061954970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88827556,0.009033857,0.08824913,0.0002460164,0.00007650099,0.00018691576,0.00086493866,0.0006218849,0.012445245],"genre_scores_gemma":[0.97334474,0.003149971,0.017906785,0.00014050663,0.000030198333,0.00014484492,0.00031414462,0.000074951866,0.0048939083],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99956137,0.00014687372,0.000026355896,0.000070078844,0.0001490791,0.000046286],"domain_scores_gemma":[0.9984005,0.0009857542,0.00018063097,0.00009591025,0.0002757418,0.00006135616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012321227,0.00044647092,0.00021256851,0.0011601312,0.0003869239,0.0008589281,0.00029346542,0.00059057475,0.0029008384],"category_scores_gemma":[0.0015275097,0.00028299296,0.00022925694,0.0006232636,0.0005329766,0.0013100273,0.00043714288,0.0007103897,0.00034689542],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017269818,0.00012996196,0.0055803508,0.00064793235,0.00010061855,0.00016677359,0.00055527827,0.0019180225,0.95265204,0.002116561,0.00041711592,0.03398838],"study_design_scores_gemma":[0.00006254624,0.0012597672,0.044191986,0.00006483838,0.00030591447,0.0009551358,0.00072404294,0.035322625,0.91070247,0.0013881831,0.0049292496,0.00009319452],"about_ca_topic_score_codex":0.003086656,"about_ca_topic_score_gemma":0.002105546,"teacher_disagreement_score":0.003086656,"about_ca_system_score_codex":0.00048040895,"about_ca_system_score_gemma":0.0005268686,"threshold_uncertainty_score":0.009704292},"labels":[],"label_agreement":null},{"id":"W2064715455","doi":"10.1007/s11095-006-9080-8","title":"Coupling Between Chemical Reactivity and Structural Relaxation in Pharmaceutical Glasses","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":104,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Merck Canada","keywords":"Amorphous solid; Differential scanning calorimetry; Relaxation (psychology); Chemistry; Isothermal microcalorimetry; Chemical stability; Molecular dynamics; Enthalpy; Reactivity (psychology); Glass transition; Diffusion; Molecule; Organic chemistry; Physical chemistry; Chemical physics; Materials science; Thermodynamics; Computational chemistry; Polymer","score_opus":0.3319899613728902,"score_gpt":0.5513424900024531,"score_spread":0.21935252862956284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064715455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98725224,0.0011209357,0.0071162595,0.00024178946,0.00003821617,0.000021246622,0.000049930204,0.0000661678,0.004093172],"genre_scores_gemma":[0.99850357,0.00023774835,0.00047245732,0.00005824302,0.000012980341,0.000008732733,0.000026885633,0.00001700397,0.00066234905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998858,0.00002674617,0.000004418653,0.000028787641,0.000026872445,0.000027429596],"domain_scores_gemma":[0.9997081,0.00016339569,0.00006299015,0.000019649327,0.000020301291,0.000025514597],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002741461,0.0001657395,0.00014524149,0.00031632077,0.00030631345,0.00026312214,0.0003126674,0.0003061269,0.0026395381],"category_scores_gemma":[0.00051618984,0.00030818552,0.00015980873,0.0001645847,0.0006732383,0.00048452313,0.0003746415,0.00059372827,0.00016072487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023418112,0.000026810449,0.0009123858,0.000077299665,0.000015474214,0.00012744682,0.0001714332,0.0012751666,0.9896506,0.002899913,0.00011520396,0.004494108],"study_design_scores_gemma":[0.00006678305,0.000460456,0.020040851,0.000020316988,0.000036774894,0.00024098172,0.00025703578,0.02563773,0.94799817,0.00332498,0.001863055,0.00005286613],"about_ca_topic_score_codex":0.0007819035,"about_ca_topic_score_gemma":0.0007988049,"teacher_disagreement_score":0.0026395381,"about_ca_system_score_codex":0.0002492204,"about_ca_system_score_gemma":0.00014639639,"threshold_uncertainty_score":0.00883013},"labels":[],"label_agreement":null},{"id":"W2064976064","doi":"10.1007/s11095-004-7684-4","title":"Stimulation of Triglyceride-Rich Lipoprotein Secretion by Polysorbate 80: In Vitro and in Vivo Correlation Using Caco-2 Cells and a Cannulated Rat Intestinal Lymphatic Model","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Polysorbate; Chylomicron; In vivo; Chemistry; Triglyceride; Lipoprotein; Pharmacology; Endocrinology; Internal medicine; Biochemistry; Very low-density lipoprotein; Biology; Cholesterol; Medicine; Pulmonary surfactant","score_opus":0.09554995619871755,"score_gpt":0.41286782428884894,"score_spread":0.3173178680901314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064976064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99035674,0.0017260795,0.005935983,0.00015192137,0.00007531808,0.000069589034,0.0003668498,0.00014114652,0.0011763691],"genre_scores_gemma":[0.9873877,0.001757094,0.0068144784,0.00008352076,0.00007504753,0.00011841036,0.0010362649,0.000075579665,0.0026517834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993709,0.0002077826,0.000050878494,0.00008674009,0.000097963646,0.00018581389],"domain_scores_gemma":[0.99920267,0.0002866198,0.000121991055,0.00018912985,0.00006287645,0.00013671814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009659211,0.0012062857,0.0009140622,0.00071084005,0.0003866997,0.0006298651,0.00037759598,0.0006700595,0.0012066581],"category_scores_gemma":[0.00039612234,0.000574847,0.001464062,0.000959133,0.0011592314,0.0011033356,0.0005024313,0.0017174818,0.0006063086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014824807,0.00016718412,0.0002854141,0.000046372297,0.000009776295,0.00006854166,0.000048359652,0.000062870735,0.9972488,0.00004577133,0.000017928345,0.0005165708],"study_design_scores_gemma":[0.000055570275,0.0014123147,0.004058949,0.000004615942,0.000034799938,0.00010551119,0.000048978854,0.0006599262,0.99318075,0.000032987817,0.0003952165,0.000010538442],"about_ca_topic_score_codex":0.0008069386,"about_ca_topic_score_gemma":0.0011988413,"teacher_disagreement_score":0.0012066581,"about_ca_system_score_codex":0.00060053007,"about_ca_system_score_gemma":0.0005216527,"threshold_uncertainty_score":0.0051083565},"labels":[],"label_agreement":null},{"id":"W2066535896","doi":"10.1007/s11095-015-1675-5","title":"Unstirred Water Layers and the Kinetics of Organic Cation Transport","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Kinetics; Transporter; Chemistry; Biophysics; Heterologous; Membrane transport; Organic cation transport proteins; Chinese hamster ovary cell; Enzyme kinetics; Biochemistry; Membrane; Biology; Enzyme","score_opus":0.19190693690807237,"score_gpt":0.44161630664528956,"score_spread":0.2497093697372172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066535896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97645444,0.0113687,0.009056051,0.00058678654,0.000059924037,0.000020357196,0.0000899435,0.0000394539,0.0023243504],"genre_scores_gemma":[0.993946,0.0027132106,0.0012400537,0.000058636706,0.000012817826,0.0000048607853,0.000055075107,0.000011883959,0.0019574652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998053,0.000047836216,0.000010172727,0.000029823499,0.000053273732,0.000053707132],"domain_scores_gemma":[0.99930084,0.00038950064,0.00015405063,0.00002608612,0.0000864393,0.00004306883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007263695,0.0002313981,0.00015679807,0.00027290866,0.0001768741,0.001069407,0.00030818378,0.00052687014,0.0008923163],"category_scores_gemma":[0.0014974759,0.0003429884,0.0001900741,0.00016697073,0.0004896662,0.0019424907,0.000316303,0.00065357785,0.00024275812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069089665,0.00004139521,0.002042012,0.00019644281,0.000041180145,0.00017591815,0.00024756536,0.004320749,0.97710985,0.0066642785,0.00016232124,0.008307416],"study_design_scores_gemma":[0.000054875432,0.00039265066,0.010685742,0.00003816803,0.00005152612,0.00025991065,0.00046157034,0.056965474,0.9190942,0.0062175463,0.0057040583,0.00007426544],"about_ca_topic_score_codex":0.0021408398,"about_ca_topic_score_gemma":0.0014155579,"teacher_disagreement_score":0.0021408398,"about_ca_system_score_codex":0.0007087114,"about_ca_system_score_gemma":0.00044252884,"threshold_uncertainty_score":0.0051420927},"labels":[],"label_agreement":null},{"id":"W2067027803","doi":"10.1007/s11095-011-0459-9","title":"Activation of Antigen-Specific T Cell-Responses by Mannan-Decorated PLGA Nanoparticles","year":2011,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; University of Alberta","funders":"","keywords":"Antigen; PLGA; Ovalbumin; T cell; Chemistry; Antigen-presenting cell; Dendritic cell; CD8; Immune system; In vitro; Cell biology; Molecular biology; Immunology; Biology; Biochemistry","score_opus":0.22929416235649283,"score_gpt":0.41231077922939596,"score_spread":0.18301661687290313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067027803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958264,0.0005924699,0.0020478198,0.0000605214,0.000030071647,0.000020154233,0.000028731918,0.00003357308,0.001360359],"genre_scores_gemma":[0.9972824,0.00019918091,0.0009607508,0.000042511158,0.000008965273,0.000017160703,0.00004445039,0.000008443036,0.0014362507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999093,0.000017854627,0.0000059066724,0.000015185387,0.000016744902,0.00003504178],"domain_scores_gemma":[0.9999571,0.000015781741,0.00000762416,0.000006119808,0.000005303253,0.000008111883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011413903,0.00034621416,0.00014857162,0.00011300074,0.00011197605,0.00023931739,0.00012058442,0.00031366758,0.00096487114],"category_scores_gemma":[0.00011540737,0.00014916796,0.00023063135,0.00005531469,0.00013132562,0.00019103891,0.00017651929,0.00038772848,0.00025254957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019578316,0.000023571078,0.00005016479,0.000024860432,0.0000030992182,0.000041302817,0.00001149009,0.00014837828,0.9982352,0.0000904452,0.000031031974,0.001144594],"study_design_scores_gemma":[0.000023744617,0.00018600243,0.00055070856,0.0000029159244,0.000007737605,0.000059594528,0.000009637701,0.0012796024,0.9972796,0.000046063426,0.0005515539,0.0000028596426],"about_ca_topic_score_codex":0.00029285278,"about_ca_topic_score_gemma":0.0004056111,"teacher_disagreement_score":0.00096487114,"about_ca_system_score_codex":0.00021572511,"about_ca_system_score_gemma":0.00012358227,"threshold_uncertainty_score":0.00322783},"labels":[],"label_agreement":null},{"id":"W2067860177","doi":"10.1007/s11095-014-1334-2","title":"Magnetic Resonance Microscopy for Assessment of Morphological Changes in Hydrating Hydroxypropylmethylcellulose Matrix Tablets In Situ–Is it Possible to Detect Phenomena Related to Drug Dissolution Within the Hydrated Matrices?","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thunder Bay Regional Research Institute; National Research Council Canada; National Research Council Institute for Biodiagnostics","funders":"","keywords":"Dissolution; Relaxometry; Matrix (chemical analysis); Chemistry; Dosage form; Solubility; Dissolution testing; Swelling; Ketoprofen; Chemical engineering; Nuclear magnetic resonance; Chromatography; Materials science; Magnetic resonance imaging; Spin echo; Biopharmaceutics Classification System; Organic chemistry; Composite material","score_opus":0.16931989595131736,"score_gpt":0.5146945170127566,"score_spread":0.34537462106143924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067860177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93984854,0.006918145,0.050299827,0.00013219423,0.0000572907,0.000101383805,0.00025027225,0.00023782164,0.002154605],"genre_scores_gemma":[0.94508183,0.003894633,0.048203968,0.00010638036,0.00004422805,0.00010085741,0.0002269742,0.00005123801,0.0022898868],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998946,0.00002313768,0.000006607994,0.000027277883,0.00003637785,0.000012072784],"domain_scores_gemma":[0.999838,0.000053992477,0.000044260738,0.000013881856,0.000031101696,0.000018729188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031793196,0.00034195735,0.00013574233,0.00035052348,0.00011439706,0.00016443912,0.0001412266,0.0004564164,0.00094898563],"category_scores_gemma":[0.00027465206,0.00016473667,0.0001418945,0.00011930891,0.00021709767,0.00023906221,0.0001278691,0.00031786738,0.00025205812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016333304,0.000003790687,0.00007007727,0.0000232109,0.0000016793693,0.000018329683,0.000007625108,0.000016938175,0.9991062,0.000009646536,0.00000560918,0.0007205854],"study_design_scores_gemma":[0.0000055943574,0.0002691151,0.010021775,0.000012425907,0.000024273402,0.0004523293,0.000041003717,0.0020516254,0.9863646,0.000028158336,0.0007210889,0.00000803292],"about_ca_topic_score_codex":0.0005532146,"about_ca_topic_score_gemma":0.0006951132,"teacher_disagreement_score":0.00094898563,"about_ca_system_score_codex":0.00011936273,"about_ca_system_score_gemma":0.00010862043,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W2069003092","doi":"10.1007/s11095-009-9916-0","title":"Composite Hydrogel Formulations of Stratifin to Control MMP-1 Expression in Dermal Fibroblasts","year":2009,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biological Activity of Diterpenoids and Biflavonoids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Fibroblast; Biomedical engineering; Pharmaceutical technology; Composite number; Tissue engineering; Chemistry; Medicine; Cell biology; Surgery; Materials science; Biology; Internal medicine; In vitro; Biochemistry; Composite material; Chromatography","score_opus":0.07671961905611405,"score_gpt":0.4326419940439274,"score_spread":0.3559223749878133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069003092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98766404,0.0029060866,0.006914908,0.00007432971,0.00006658503,0.00005199255,0.00024181885,0.00005925867,0.002020809],"genre_scores_gemma":[0.992516,0.0010439906,0.004341647,0.000037981812,0.000017088152,0.000032849777,0.00014639404,0.0000116484725,0.0018524961],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999231,0.000009228943,0.0000078966805,0.000019039979,0.000018219485,0.000022535318],"domain_scores_gemma":[0.99992776,0.000025823489,0.000015592483,0.0000055844607,0.00000943747,0.000015806658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021658246,0.00022396407,0.00015704808,0.00021911798,0.00009939943,0.0001822258,0.00012179225,0.00017811125,0.0011221579],"category_scores_gemma":[0.00014023465,0.00008101861,0.00014450519,0.00016676549,0.00009195118,0.00020057015,0.00008641036,0.00025674363,0.00011062848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007005048,0.000018283503,0.00003097209,0.000033452965,0.0000026962412,0.000017133669,0.000009677403,0.00007739984,0.99805295,0.00005646085,0.000022137816,0.0016087154],"study_design_scores_gemma":[0.0000104049905,0.00012154584,0.00029843938,0.000002755836,0.0000068002355,0.00002101002,0.000004300323,0.00027074452,0.99857116,0.000008956123,0.0006824664,0.00000152932],"about_ca_topic_score_codex":0.00060461403,"about_ca_topic_score_gemma":0.0014344321,"teacher_disagreement_score":0.0011221579,"about_ca_system_score_codex":0.00025866134,"about_ca_system_score_gemma":0.00014526879,"threshold_uncertainty_score":0.0037539601},"labels":[],"label_agreement":null},{"id":"W2072998594","doi":"10.1007/s11095-013-1255-5","title":"The Effect of Polymerization Method in Stereo-active Block Copolymers on the Stability of Polymeric Micelles and their Drug Release Profile","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Copolymer; Micelle; Polymerization; Drug; Chemistry; Polymer chemistry; Chemical engineering; Polymer; Materials science; Organic chemistry; Pharmacology; Medicine; Aqueous solution","score_opus":0.05213270514825473,"score_gpt":0.3910300245318773,"score_spread":0.33889731938362255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072998594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934203,0.002169353,0.0026060801,0.00004640197,0.000043725766,0.00002592208,0.00013280404,0.0000549578,0.0015003987],"genre_scores_gemma":[0.99475926,0.0013256171,0.0020587437,0.000023035054,0.000027622722,0.00002892171,0.00010361926,0.00004379673,0.0016293174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997507,0.00005753987,0.00003240722,0.00006684686,0.00005249242,0.00004005515],"domain_scores_gemma":[0.9994143,0.00026531803,0.00015844373,0.00003683381,0.00007138017,0.000053761294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004659571,0.00041142607,0.0001759206,0.00031895415,0.00016738438,0.00024023802,0.00015036209,0.0002552475,0.0015710883],"category_scores_gemma":[0.001034794,0.00025318124,0.00022703731,0.00028302884,0.0002531962,0.00049527624,0.00015646187,0.00042282656,0.00039884375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007023559,0.000064275504,0.00034255153,0.000071241484,0.000009390509,0.000047192134,0.0000581785,0.00017840759,0.9950138,0.000110829475,0.000035747013,0.0033661036],"study_design_scores_gemma":[0.000013993571,0.00034104325,0.001130296,0.000004560689,0.000021111433,0.000035249584,0.000007775933,0.0006001068,0.9973084,0.000016988104,0.00051226525,0.000008204567],"about_ca_topic_score_codex":0.0005168454,"about_ca_topic_score_gemma":0.0008497236,"teacher_disagreement_score":0.0015710883,"about_ca_system_score_codex":0.00020246758,"about_ca_system_score_gemma":0.00023152147,"threshold_uncertainty_score":0.0052558184},"labels":[],"label_agreement":null},{"id":"W2073800495","doi":"10.1007/s11095-009-0035-8","title":"Neuropilin-1 Targeting Photosensitization-Induced Early Stages of Thrombosis via Tissue Factor Release","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre d'expertise et de recherche en infrastructures urbaines","funders":"","keywords":"Tissue factor; Photosensitizer; Neuropilin 1; Cancer research; Pathology; Fibrinogen; Blood vessel; Immunohistochemistry; Photodynamic therapy; Medicine; Vascular endothelial growth factor; Chemistry; Internal medicine","score_opus":0.10575246443056634,"score_gpt":0.44896456303224774,"score_spread":0.3432120986016814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073800495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869565,0.0030997917,0.0073664687,0.00021214274,0.000046870067,0.00007393893,0.00008117258,0.00007730163,0.002085925],"genre_scores_gemma":[0.9952793,0.0010630124,0.002081998,0.000059326405,0.000019284984,0.000027910562,0.00006507558,0.0000085260035,0.0013955216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999249,0.000021827733,0.000004217181,0.000012336493,0.000012632031,0.000024148221],"domain_scores_gemma":[0.9999424,0.00001969435,0.000016574058,0.000005797991,0.0000035951482,0.000011989806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025770254,0.0002771761,0.00019579657,0.00013642474,0.00009762403,0.00022883262,0.00019849303,0.00024043073,0.00091220555],"category_scores_gemma":[0.00014789867,0.000111310146,0.00020408285,0.000059477123,0.00018954113,0.0002708332,0.00015166149,0.0005316082,0.00013992198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000221556,0.000033061227,0.00007544752,0.000034671568,0.0000055246796,0.00010880213,0.000009785246,0.000117729236,0.9965849,0.00040805334,0.00006522244,0.0023351987],"study_design_scores_gemma":[0.000055016102,0.00062904943,0.0017820441,0.000004174866,0.000016074902,0.0003870796,0.000011660428,0.0013838257,0.99452436,0.0001176328,0.0010849598,0.0000041266053],"about_ca_topic_score_codex":0.00032423736,"about_ca_topic_score_gemma":0.0005860003,"teacher_disagreement_score":0.00091220555,"about_ca_system_score_codex":0.00034449765,"about_ca_system_score_gemma":0.00013590124,"threshold_uncertainty_score":0.0030516982},"labels":[],"label_agreement":null},{"id":"W2074983458","doi":"10.1007/s11095-013-1174-5","title":"Use of a Fundamental Approach to Spray-Drying Formulation Design to Facilitate the Development of Multi-Component Dry Powder Aerosols for Respiratory Drug Delivery","year":2013,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Spray drying; Particle (ecology); Aerosol; Trehalose; Materials science; Chemistry; Particle size; Biological system; Chemical engineering; Chromatography; Nanotechnology; Organic chemistry; Engineering","score_opus":0.6027481095781996,"score_gpt":0.46019584005711384,"score_spread":0.14255226952108574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074983458","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11111543,0.0012737612,0.8813984,0.0003380356,0.00021160225,0.0005656261,0.000081853934,0.0004385718,0.0045767133],"genre_scores_gemma":[0.31911707,0.0017021786,0.6755008,0.00019174308,0.00004393312,0.00031360434,0.00009153078,0.00012308113,0.0029160946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996117,0.00004927423,0.000030115907,0.000074409036,0.00020894938,0.00002557762],"domain_scores_gemma":[0.99962556,0.00010509987,0.00008920221,0.000051530358,0.000112334434,0.00001610554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008190957,0.00042555932,0.00033823584,0.00031592566,0.0003965646,0.00061523466,0.00054555945,0.00053048425,0.0007547192],"category_scores_gemma":[0.0008927572,0.00034055466,0.0004768212,0.00018069975,0.00041506268,0.0005589949,0.00043421495,0.001229119,0.00028462647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027421922,0.00007834729,0.00011800025,0.00012844281,0.000010404497,0.000030882944,0.00004706536,0.002051745,0.97495776,0.0033940508,0.00012318109,0.019032624],"study_design_scores_gemma":[0.000031851567,0.0005578538,0.0005146387,0.000016637372,0.000025808604,0.0002113912,0.000012485571,0.022487918,0.9679378,0.0006918136,0.0074919076,0.000019790634],"about_ca_topic_score_codex":0.00036635197,"about_ca_topic_score_gemma":0.0009708914,"teacher_disagreement_score":0.0008190957,"about_ca_system_score_codex":0.00040474627,"about_ca_system_score_gemma":0.0008187344,"threshold_uncertainty_score":0.004331887},"labels":[],"label_agreement":null},{"id":"W2075418303","doi":"10.1007/s11095-007-9384-3","title":"In Situ-Forming Oleogel Implant for Rivastigmine Delivery","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Food Chemistry and Fat Analysis","field":"Agricultural and Biological Sciences","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Rivastigmine; Chemistry; Differential scanning calorimetry; In vivo; Bioavailability; Chromatography; Pharmacology; Donepezil; Medicine","score_opus":0.20094704956608106,"score_gpt":0.4466193257258531,"score_spread":0.24567227615977205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075418303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98013455,0.001888428,0.0154139735,0.00013239912,0.000110664536,0.00003922252,0.00018742522,0.00019442562,0.0018988481],"genre_scores_gemma":[0.99061966,0.0006424732,0.005327642,0.000043414864,0.000016466358,0.000019409217,0.00009915628,0.00005432963,0.0031775336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993944,0.0000072298017,0.00000443167,0.000013787223,0.000016054631,0.00001899178],"domain_scores_gemma":[0.99995506,0.000013464534,0.000013966826,0.000005697829,0.000005114968,0.0000067117758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013376192,0.0002555416,0.00023523404,0.00017259196,0.00013059235,0.00021650316,0.00022365614,0.0003482201,0.0008180638],"category_scores_gemma":[0.00013571451,0.00012753898,0.00026254202,0.000081254984,0.00018039934,0.000404656,0.00015427111,0.0002493402,0.00021268995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008290711,0.000009730857,0.000020715277,0.000020964499,0.000002549713,0.000034102195,0.000007436945,0.00007092029,0.99859744,0.000040099632,0.000023556142,0.001089666],"study_design_scores_gemma":[0.000010910091,0.00010964482,0.000164036,0.0000013669678,0.000009355875,0.00012554367,0.0000061590245,0.00041986143,0.99803823,0.00001666787,0.0010951028,0.0000030042463],"about_ca_topic_score_codex":0.00022579687,"about_ca_topic_score_gemma":0.0003839045,"teacher_disagreement_score":0.0008180638,"about_ca_system_score_codex":0.00016639095,"about_ca_system_score_gemma":0.00013480394,"threshold_uncertainty_score":0.0027367473},"labels":[],"label_agreement":null},{"id":"W2076038066","doi":"10.1007/s11095-007-9428-8","title":"Influence of Plasma Cholesterol and Triglyceride Concentrations and Eritoran (E5564) Micelle Size on its Plasma Pharmacokinetics and Ex Vivo Activity Following Single Intravenous Bolus Dose Into Healthy Female Rabbits","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"University of British Columbia; Eisai","keywords":"Pharmacokinetics; Triglyceride; Ex vivo; Internal medicine; Pharmacodynamics; Endocrinology; Cholesterol; Pharmacology; In vivo; Bolus (digestion); Chemistry; Blood plasma; Medicine; Biology","score_opus":0.07804843932173165,"score_gpt":0.4022562446270074,"score_spread":0.3242078053052757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076038066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99755543,0.00068348664,0.0009896926,0.000058767757,0.000033370925,0.000030325082,0.00016097691,0.00004983262,0.00043806995],"genre_scores_gemma":[0.9944534,0.0008089085,0.0010980951,0.00006648631,0.00004902389,0.00007288284,0.0002578456,0.000037285165,0.003156021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969935,0.000061290615,0.000028124974,0.00007706283,0.000042617354,0.00009157305],"domain_scores_gemma":[0.9996406,0.00012374333,0.00009943027,0.00004603705,0.000024913505,0.000065317065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004745787,0.0004919966,0.00055320107,0.00028060237,0.00013431521,0.0004067045,0.00030751812,0.00043500646,0.0010564624],"category_scores_gemma":[0.0005975492,0.00029241253,0.0003696992,0.00019051012,0.0005517653,0.0006863804,0.00016398847,0.00083384465,0.000417708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029766122,0.0009830948,0.0005995627,0.00006964168,0.00004429533,0.00012559879,0.00010768164,0.00038698406,0.9581608,0.00017863908,0.00010690063,0.009470528],"study_design_scores_gemma":[0.00042241425,0.012433734,0.0030829245,0.000005878146,0.00010412768,0.00011668966,0.000037874663,0.0011501616,0.9817199,0.00008370597,0.00082474505,0.000017866001],"about_ca_topic_score_codex":0.0006467877,"about_ca_topic_score_gemma":0.0006185321,"teacher_disagreement_score":0.0010564624,"about_ca_system_score_codex":0.00027814443,"about_ca_system_score_gemma":0.00028622957,"threshold_uncertainty_score":0.0035341978},"labels":[],"label_agreement":null},{"id":"W2076052464","doi":"10.1007/s11095-010-0049-2","title":"Physiological Modeling to Understand the Impact of Enzymes and Transporters on Drug and Metabolite Data and Bioavailability Estimates","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Metabolite; Bioavailability; Pharmacology; Pharmacokinetics; Physiologically based pharmacokinetic modelling; Drug; Active metabolite; Drug metabolism; Chemistry; Dosing; Biology; Biochemistry","score_opus":0.31877611914570686,"score_gpt":0.5165201941526556,"score_spread":0.19774407500694874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076052464","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16684633,0.0008671434,0.8200286,0.0012638784,0.0001131006,0.00011803309,0.001009567,0.0009404358,0.008812938],"genre_scores_gemma":[0.95585376,0.0007588713,0.037935473,0.00029630895,0.00005449833,0.00017842544,0.00055998476,0.00018113744,0.004181472],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9997012,0.00012365196,0.000017489392,0.00005609034,0.000079703495,0.00002182747],"domain_scores_gemma":[0.9989876,0.00074935914,0.00006558252,0.000054186577,0.00012788312,0.00001534301],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007274758,0.00060200086,0.0007851566,0.00023279757,0.00019374097,0.0008327148,0.00063814176,0.0009024527,0.0015124255],"category_scores_gemma":[0.0028118668,0.0002960604,0.0007832144,0.0002834163,0.00024095856,0.0010733616,0.0002698005,0.00090902735,0.00044575497],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009578199,0.00007145458,0.0015810276,0.00012293209,0.00005282974,0.000100496654,0.00004083795,0.9671513,0.01690047,0.0040594605,0.0006400028,0.00918338],"study_design_scores_gemma":[0.0000083114655,0.000039140003,0.0003890418,0.0000029741307,0.000012337908,0.000037924794,0.000007380424,0.99363035,0.0040073455,0.0012497007,0.00060937536,0.000006144936],"about_ca_topic_score_codex":0.006681192,"about_ca_topic_score_gemma":0.0023233371,"teacher_disagreement_score":0.006681192,"about_ca_system_score_codex":0.00053046655,"about_ca_system_score_gemma":0.00096698455,"threshold_uncertainty_score":0.013284624},"labels":[],"label_agreement":null},{"id":"W2076265848","doi":"10.1007/s11095-006-0276-8","title":"Acute P-407 Administration to Mice Causes Hypercholesterolemia by Inducing Cholesterolgenesis and Down-Regulating Low-Density Lipoprotein Receptor Expression","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; LDL receptor; Microsomal triglyceride transfer protein; Scavenger receptor; Chemistry; ABCA1; Cholesteryl ester; Poloxamer 407; Lipoprotein; Reductase; Receptor; Reverse cholesterol transport; HMG-CoA reductase; Cholesterol; Sterol O-acyltransferase; Very low-density lipoprotein; Biology; Transporter; Biochemistry; Medicine; Enzyme","score_opus":0.06364936320868358,"score_gpt":0.41147324712052324,"score_spread":0.34782388391183966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076265848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873007,0.001615488,0.004506293,0.0008170795,0.00026912524,0.00011609492,0.0014953578,0.0009834922,0.002896373],"genre_scores_gemma":[0.9750649,0.0020345722,0.005127338,0.0003559299,0.00014715722,0.0003582736,0.0026816071,0.00034134905,0.0138888955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993119,0.00008125935,0.000051527895,0.00009195938,0.00018342858,0.00027984803],"domain_scores_gemma":[0.9992501,0.000081694496,0.00017831282,0.00007571678,0.000049652015,0.00036447923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027035514,0.001636345,0.0012411298,0.0018057672,0.00067067734,0.0007480069,0.0006345015,0.001259633,0.003965663],"category_scores_gemma":[0.00025283726,0.00072134484,0.0010251567,0.0007188044,0.0016553206,0.00062388903,0.00050228334,0.0030544288,0.0017523951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024917002,0.0004897218,0.00029430198,0.00005700491,0.000028314094,0.00029697505,0.00003640362,0.00007780272,0.99389243,0.00031345856,0.00024022404,0.0017816805],"study_design_scores_gemma":[0.00013169578,0.0010714224,0.0008912738,0.0000068496115,0.000032046362,0.00019190335,0.000040374245,0.00030018206,0.99617815,0.00009974737,0.0010463609,0.000010075529],"about_ca_topic_score_codex":0.0017557514,"about_ca_topic_score_gemma":0.0027726328,"teacher_disagreement_score":0.003965663,"about_ca_system_score_codex":0.0008597604,"about_ca_system_score_gemma":0.0011529805,"threshold_uncertainty_score":0.013266504},"labels":[],"label_agreement":null},{"id":"W2078273989","doi":"10.1007/s11095-004-1874-y","title":"Cross-linked Small Polyethylenimines: While Still Nontoxic, Deliver DNA Efficiently to Mammalian Cells in Vitro and in Vivo","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":236,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Science Foundation","keywords":"Polyethylenimine; Gene delivery; Cytotoxicity; In vivo; Transfection; In vitro; Luciferase; Chemistry; Molecular biology; Biophysics; Biochemistry; Biology; Cell biology; Gene; Genetics","score_opus":0.08979086800290556,"score_gpt":0.40936548364949027,"score_spread":0.31957461564658474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078273989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95708436,0.0051105423,0.032127086,0.00025696133,0.0000818721,0.00014460983,0.0002768921,0.00035476152,0.0045627784],"genre_scores_gemma":[0.9717358,0.0022254197,0.018021617,0.00019896321,0.000024573306,0.00009360324,0.00053774245,0.00009637395,0.00706588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998472,0.000028548895,0.000013871039,0.00003862385,0.000048814,0.000022958766],"domain_scores_gemma":[0.9997067,0.00010093746,0.000082280756,0.00004356628,0.000025913292,0.000040640745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038707498,0.0004275862,0.00025467062,0.00027164546,0.00015428466,0.00036266216,0.00032947576,0.00069896335,0.00080496486],"category_scores_gemma":[0.00038756535,0.0002802671,0.0002527811,0.00022479711,0.0003035363,0.0004731425,0.0002690145,0.0005024552,0.0005889118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000248596,0.000006382526,0.000028271026,0.000018290577,0.0000034332675,0.000020886204,0.0000087757635,0.000033531975,0.99883896,0.00009638599,0.000012933078,0.0009072038],"study_design_scores_gemma":[0.00000547451,0.00008903706,0.00036712733,0.0000021730891,0.00000586677,0.00013140966,0.0000038028927,0.00013691498,0.9979672,0.00003287492,0.0012563271,0.0000018982565],"about_ca_topic_score_codex":0.00030661936,"about_ca_topic_score_gemma":0.00044785516,"teacher_disagreement_score":0.00080496486,"about_ca_system_score_codex":0.00030315254,"about_ca_system_score_gemma":0.00025195864,"threshold_uncertainty_score":0.0026928782},"labels":[],"label_agreement":null},{"id":"W2079082507","doi":"10.1007/s11095-006-9224-x","title":"Novel Liposomal Formulation for Targeted Gene Delivery","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"","keywords":"Transfection; Gene delivery; Molecular biology; In vivo; Chemistry; DNA; Transferrin receptor; Liposome; Monoclonal antibody; Transferrin; PEG ratio; Biophysics; Biology; Biochemistry; Gene; Antibody; Immunology","score_opus":0.16669841775182576,"score_gpt":0.46492182198293935,"score_spread":0.2982234042311136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079082507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7025761,0.0108388215,0.26884636,0.0013433204,0.0005896759,0.00059611467,0.00046111312,0.00065002043,0.014098426],"genre_scores_gemma":[0.8974326,0.0046240166,0.07354587,0.00047533654,0.0000786955,0.0003085408,0.00036359017,0.00010545124,0.023065777],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999331,0.000010591024,0.000005189887,0.000016888067,0.000021489952,0.000012728273],"domain_scores_gemma":[0.9999492,0.000009297684,0.000012167208,0.000003589691,0.00001468788,0.000011122089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019982514,0.00027561974,0.00019990974,0.00015556112,0.00018474282,0.00026404846,0.00023926787,0.00036812696,0.0017773617],"category_scores_gemma":[0.000120731,0.00012205279,0.00014027103,0.00010332456,0.00017457879,0.0003981106,0.0002265877,0.0004426506,0.0007102584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064059175,0.000033790828,0.000024718665,0.000074632946,0.0000037741765,0.00008589364,0.000015329428,0.0001054018,0.9920129,0.0008384281,0.00018791192,0.0065530315],"study_design_scores_gemma":[0.000026336262,0.00015685726,0.00013288914,0.0000079797155,0.00001371188,0.00023104774,0.0000087588305,0.0014770193,0.9904468,0.00013291196,0.0073579038,0.000007773196],"about_ca_topic_score_codex":0.0002561207,"about_ca_topic_score_gemma":0.00033839195,"teacher_disagreement_score":0.0017773617,"about_ca_system_score_codex":0.00026822902,"about_ca_system_score_gemma":0.0002537557,"threshold_uncertainty_score":0.0059458017},"labels":[],"label_agreement":null},{"id":"W2080310984","doi":"10.1007/s11095-008-9591-6","title":"Characterization of Polyion Complex Micelles Designed to Address the Challenges of Oligonucleotide Delivery","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Micelle; Cationic polymerization; Copolymer; Polymer; Dynamic light scattering; Atom-transfer radical-polymerization; Ethylene glycol; Chemistry; Polymer chemistry; PEG ratio; Methacrylate; Polymerization; Nanogel; Combinatorial chemistry; Chemical engineering; Materials science; Nanoparticle; Organic chemistry; Drug delivery; Aqueous solution; Nanotechnology","score_opus":0.23622214807984937,"score_gpt":0.423352600319551,"score_spread":0.18713045223970165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080310984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866889,0.00059404527,0.01099604,0.00008574168,0.000028226541,0.00011211099,0.00014674598,0.00007040069,0.0012778477],"genre_scores_gemma":[0.98598564,0.0003648976,0.009116401,0.00013293621,0.000007394587,0.000082398816,0.00050119264,0.00006206197,0.0037469715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983454,0.000024540672,0.000016398923,0.000032165088,0.00005966151,0.00003256082],"domain_scores_gemma":[0.9996973,0.00007754319,0.00006237179,0.000020332172,0.00010414236,0.00003837254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041145252,0.0002221853,0.000153954,0.00018374706,0.00015645336,0.00032096833,0.00015342906,0.00034574975,0.0008946656],"category_scores_gemma":[0.0006512111,0.00012370324,0.00014018158,0.00013878042,0.00019301043,0.0002688399,0.00010960261,0.00033225247,0.00026572868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004783333,0.000011658249,0.000077645156,0.000012655053,0.0000022440902,0.000015975807,0.000014077653,0.000052072053,0.9991635,0.000058905676,0.000014132226,0.0005292474],"study_design_scores_gemma":[0.000010569464,0.00009393538,0.00066133484,0.0000022570575,0.0000048021648,0.000060059847,0.000007222618,0.00071805145,0.997614,0.000016641601,0.0008081219,0.000003001993],"about_ca_topic_score_codex":0.00055754784,"about_ca_topic_score_gemma":0.0005675299,"teacher_disagreement_score":0.0008946656,"about_ca_system_score_codex":0.00023334644,"about_ca_system_score_gemma":0.00023542519,"threshold_uncertainty_score":0.002992928},"labels":[],"label_agreement":null},{"id":"W2081729073","doi":"10.1007/s11095-008-9739-4","title":"Pharmacokinetic and Pharmacodynamic Modeling of a Humanized Anti-IL-13 Antibody in Naive and Ascaris-Challenged Cynomolgus Monkeys","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Ascaris; Pharmacology; Pharmacokinetics; Pharmacodynamics; Immunology; Antibody; Medicine; Immune system; Helminths","score_opus":0.16963118533246593,"score_gpt":0.47905227790251814,"score_spread":0.30942109257005224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081729073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925277,0.0005841045,0.0055198325,0.000120374476,0.000017169228,0.000045585584,0.00027147093,0.00006607019,0.00084764726],"genre_scores_gemma":[0.99799746,0.00031372142,0.0009096389,0.000055473538,0.00001244663,0.000035135952,0.00013448054,0.000020660582,0.0005209675],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.999882,0.000044405126,0.0000033991842,0.00002290323,0.000020405223,0.000026815715],"domain_scores_gemma":[0.9998254,0.00009196865,0.000035591132,0.000011203102,0.000013334651,0.000022471526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029623488,0.00026201888,0.00046968606,0.00015080103,0.00015343755,0.0004407928,0.00027474633,0.00032046076,0.0006855534],"category_scores_gemma":[0.000527536,0.0001895639,0.00038420912,0.00013482798,0.00023416997,0.00019362924,0.00010078529,0.0005824516,0.0002613931],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.033665955,0.0015336231,0.014545246,0.0003611939,0.00056108384,0.0012734273,0.00046791625,0.15766814,0.734249,0.0016709258,0.0025035257,0.051499937],"study_design_scores_gemma":[0.001181174,0.02171549,0.03451648,0.000030652198,0.0008735671,0.0020912555,0.0002714359,0.7067169,0.22561696,0.0016407049,0.0052477526,0.00009764315],"about_ca_topic_score_codex":0.004738768,"about_ca_topic_score_gemma":0.002088001,"teacher_disagreement_score":0.004738768,"about_ca_system_score_codex":0.0006134599,"about_ca_system_score_gemma":0.0006279453,"threshold_uncertainty_score":0.009422362},"labels":[],"label_agreement":null},{"id":"W2082566509","doi":"10.1007/s11095-006-9186-z","title":"The Influence of Hyperlipoproteinemia on in Vitro Distribution of Amiodarone and Desethylamiodarone in Human and Rat Plasma","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Human plasma; Triglyceride; Chemistry; Metabolite; Lipoprotein; Endocrinology; In vitro; Internal medicine; Plasma lipoprotein; Ultracentrifuge; Plasma levels; Distribution (mathematics); Very low-density lipoprotein; Cholesterol; Chromatography; Biology; Biochemistry; Medicine","score_opus":0.04991407809287012,"score_gpt":0.42666584755032216,"score_spread":0.37675176945745203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082566509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98872364,0.0054534664,0.0026781098,0.00018156848,0.000099268786,0.000029528514,0.00037986026,0.00003897853,0.0024156456],"genre_scores_gemma":[0.99484444,0.0018472073,0.0014032469,0.00008595163,0.000054018892,0.000024585639,0.00045583182,0.000018776327,0.001266013],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99954,0.00023358627,0.00004105296,0.000055186985,0.000049861945,0.00008031972],"domain_scores_gemma":[0.9991941,0.0005697499,0.000056658013,0.00007724692,0.000046216865,0.00005601587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006124358,0.00039771837,0.00030262754,0.00026625718,0.00025894213,0.00046982375,0.00028972657,0.00035391148,0.0016142012],"category_scores_gemma":[0.0008206481,0.0002897995,0.00037685284,0.00025340004,0.00056729896,0.00043559237,0.00018259141,0.0006909905,0.0005291989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010734074,0.00019483248,0.0015972606,0.00015600353,0.00009010676,0.00048106298,0.00025797525,0.0005157254,0.9804028,0.00033330842,0.00014799416,0.0050887703],"study_design_scores_gemma":[0.00012876518,0.0022424841,0.010372835,0.000010726141,0.00009617569,0.00054693664,0.00014195261,0.0018787703,0.9833803,0.00011822956,0.0010666329,0.000016273681],"about_ca_topic_score_codex":0.0017653005,"about_ca_topic_score_gemma":0.0014005956,"teacher_disagreement_score":0.0017653005,"about_ca_system_score_codex":0.00025505482,"about_ca_system_score_gemma":0.00026531983,"threshold_uncertainty_score":0.0054000616},"labels":[],"label_agreement":null},{"id":"W2084887094","doi":"10.1023/b:pham.0000048200.98837.6f","title":"A Novel Oral Vehicle for Poorly Soluble HSV-Helicase Inhibitors: PK/PD Validations","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Pharmacology; Helicase; HSL and HSV; Chemistry; Medicine; Virology; Biochemistry; Virus","score_opus":0.36627273202613686,"score_gpt":0.5454829703310334,"score_spread":0.17921023830489657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084887094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9293728,0.020063974,0.03503122,0.00079759385,0.00032725726,0.0012468527,0.001331115,0.00038227992,0.011446904],"genre_scores_gemma":[0.9662602,0.0077942936,0.01541153,0.00012659453,0.000070373775,0.00030053203,0.0007969867,0.000068790076,0.009170627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980193,0.000045688208,0.000014889623,0.000038973423,0.0000549595,0.000043546755],"domain_scores_gemma":[0.9998379,0.0000524967,0.000032637217,0.00002285008,0.000030352378,0.000023737537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064472907,0.00048509665,0.0005905877,0.0003237842,0.0002991408,0.00078482076,0.00042008256,0.0004178462,0.0033965318],"category_scores_gemma":[0.00046985797,0.00023906493,0.00034637217,0.00015784633,0.00038117272,0.0008586863,0.00028381572,0.0010519229,0.0007606649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024176869,0.0006273225,0.00030065034,0.0006967641,0.000064228865,0.00029542856,0.00016140055,0.0014540284,0.91663647,0.001729038,0.0010608665,0.074556075],"study_design_scores_gemma":[0.00043568472,0.0057709026,0.00054906576,0.00003397758,0.00009728089,0.00063467823,0.0000658098,0.0020928918,0.9730356,0.00025601694,0.017008713,0.00001939262],"about_ca_topic_score_codex":0.00095592765,"about_ca_topic_score_gemma":0.0012420925,"teacher_disagreement_score":0.0033965318,"about_ca_system_score_codex":0.00043935722,"about_ca_system_score_gemma":0.0007230851,"threshold_uncertainty_score":0.011362553},"labels":[],"label_agreement":null},{"id":"W2085782819","doi":"10.1007/s11095-005-5271-y","title":"Quantitative Assessment of HIV-1 Protease Inhibitor Interactions with Drug Efflux Transporters in the Blood–Brain Barrier","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"Amprenavir; Saquinavir; Indinavir; Ritonavir; P-glycoprotein; Nelfinavir; ATP-binding cassette transporter; Pharmacology; Protease; Efflux; Protease inhibitor (pharmacology); Blood–brain barrier; Chemistry; HIV-1 protease; Biochemistry; Multiple drug resistance; Biology; Transporter; Enzyme; Virology","score_opus":0.10287843905790182,"score_gpt":0.4794567196177342,"score_spread":0.37657828055983233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085782819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9651721,0.0052698487,0.024857093,0.00017413602,0.00002483262,0.00006624281,0.00045867462,0.0001150476,0.003862041],"genre_scores_gemma":[0.9852283,0.0013669467,0.010252693,0.00007034832,0.000013843663,0.00006596467,0.00031867792,0.000022742015,0.0026604102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934703,0.00021193209,0.000025683026,0.00008649773,0.0002552922,0.000073460855],"domain_scores_gemma":[0.9991997,0.00041175197,0.00010921855,0.000042915486,0.0001942906,0.000042158452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007540736,0.0003261241,0.0004476998,0.00043694352,0.00028737637,0.00074252055,0.000390748,0.00063207006,0.0017612844],"category_scores_gemma":[0.0012723616,0.00021524762,0.00022346196,0.00045709408,0.0002873961,0.00074930646,0.00019481462,0.00071428565,0.00031964027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008294694,0.000092089766,0.0022537727,0.00014063684,0.00009930289,0.00005622976,0.00005153874,0.0014855323,0.9826728,0.0007303383,0.00016119494,0.011427116],"study_design_scores_gemma":[0.000027793376,0.00048477983,0.016103387,0.000008724315,0.00011987899,0.00028608425,0.00007315599,0.041423023,0.9393471,0.00031769637,0.0017832363,0.000025149388],"about_ca_topic_score_codex":0.0020197143,"about_ca_topic_score_gemma":0.0015219222,"teacher_disagreement_score":0.0020197143,"about_ca_system_score_codex":0.0006021329,"about_ca_system_score_gemma":0.00033724334,"threshold_uncertainty_score":0.005892098},"labels":[],"label_agreement":null},{"id":"W2087050026","doi":"10.1007/s11095-006-9033-2","title":"Screening of Lipid Carriers and Characterization of Drug-Polymer-Lipid Interactions for the Rational Design of Polymer-Lipid Hybrid Nanoparticles (PLN)","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Differential scanning calorimetry; Isothermal titration calorimetry; Chemistry; Solubility; Polymer; Chromatography; Organic chemistry; Physical chemistry; Thermodynamics","score_opus":0.25938578496630527,"score_gpt":0.481860576938902,"score_spread":0.22247479197259673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087050026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96727204,0.00081070745,0.030044422,0.00012983818,0.000010759474,0.00022812861,0.00017866514,0.000058472226,0.0012669468],"genre_scores_gemma":[0.9662837,0.0005892164,0.031326115,0.000040235,0.0000041063927,0.00014475411,0.0003015301,0.000028007134,0.0012824626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997888,0.000065307875,0.000020902356,0.000044098375,0.0000600337,0.000020831016],"domain_scores_gemma":[0.9997491,0.000116143565,0.000046358753,0.000019238116,0.00004742618,0.000021745676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006021236,0.00039776537,0.00030851536,0.00030144205,0.0002491109,0.00032348366,0.00019870586,0.0004067204,0.0006236685],"category_scores_gemma":[0.0007825057,0.00023278335,0.00023236935,0.00019797757,0.00031039235,0.0005112494,0.00022409928,0.00029673663,0.00023767856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056051467,0.00004429442,0.00011217078,0.000036492835,0.000002554723,0.000027791266,0.000015488124,0.00068377884,0.9973435,0.000117524716,0.000009334662,0.0015511452],"study_design_scores_gemma":[0.000007622132,0.00014106373,0.0001884988,0.0000026553198,0.000006374108,0.000036694244,0.0000057300235,0.0018898399,0.99726105,0.000028391049,0.0004290442,0.0000030167673],"about_ca_topic_score_codex":0.000614188,"about_ca_topic_score_gemma":0.0012626919,"teacher_disagreement_score":0.0006236685,"about_ca_system_score_codex":0.00042624402,"about_ca_system_score_gemma":0.00045135836,"threshold_uncertainty_score":0.0031843781},"labels":[],"label_agreement":null},{"id":"W2087079029","doi":"10.1007/s11095-008-9642-z","title":"Dynamic Dissolution Testing To Establish In Vitro/In Vivo Correlations for Montelukast Sodium, a Poorly Soluble Drug","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada); University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Merck Canada; University of Alberta","keywords":"Dissolution; Solubility; IVIVC; Chemistry; Chromatography; Dissolution testing; Dosage form; Montelukast; In vivo; Biopharmaceutics Classification System; Organic chemistry","score_opus":0.3652527937097075,"score_gpt":0.5225192322891725,"score_spread":0.15726643857946504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087079029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9184911,0.004465642,0.06815941,0.0002616662,0.00011970734,0.0006158637,0.00083680335,0.0002596903,0.0067900307],"genre_scores_gemma":[0.93483865,0.0025830497,0.054215875,0.00014569482,0.00003580348,0.00029162,0.0008423012,0.000092149916,0.006954849],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990392,0.00020659961,0.00007910378,0.00015169794,0.0004420655,0.00008140166],"domain_scores_gemma":[0.9987803,0.0004919498,0.00021425779,0.00010727085,0.0003475648,0.000058573867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010699613,0.0005160307,0.00042748044,0.00062650256,0.00041783406,0.0004927696,0.00033834437,0.00044338938,0.0016870053],"category_scores_gemma":[0.0018055248,0.00032469115,0.00044468802,0.0005302734,0.00039534993,0.00062426314,0.00034835693,0.0008214273,0.00059954467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021194012,0.000107870415,0.0009627442,0.00006333312,0.000011987327,0.000037944665,0.00004939454,0.00015377294,0.992851,0.0001016285,0.00006588907,0.0053825504],"study_design_scores_gemma":[0.000014931278,0.0014321784,0.0043881577,0.000007586551,0.000041680498,0.00023321173,0.000049493796,0.0027430854,0.9892245,0.000038707854,0.0018146818,0.000011738678],"about_ca_topic_score_codex":0.0034162304,"about_ca_topic_score_gemma":0.004560863,"teacher_disagreement_score":0.0034162304,"about_ca_system_score_codex":0.0004508944,"about_ca_system_score_gemma":0.00073189696,"threshold_uncertainty_score":0.006792724},"labels":[],"label_agreement":null},{"id":"W2088963864","doi":"10.1007/s11095-013-1046-z","title":"Imaging the Cytosolic Drug Delivery Mechanism of HDL-Like Nanoparticles","year":2013,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"TD Bank Group; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Cytosol; Endocytosis; Endosome; Drug delivery; Internalization; Cell biology; Caveolae; Nanocarriers; Chemistry; Cytoplasm; Biophysics; Biochemistry; Biology; Cell","score_opus":0.07174858542968177,"score_gpt":0.39086110728014434,"score_spread":0.31911252185046257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088963864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95812273,0.001134995,0.03509915,0.0005548039,0.000058479887,0.0000475644,0.00012960454,0.00020968633,0.004642951],"genre_scores_gemma":[0.98318154,0.000550943,0.010407025,0.0002024322,0.000020678412,0.000027975406,0.00010369551,0.000040978215,0.0054647187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999399,0.000009179958,0.0000022988952,0.000016083679,0.000012164785,0.000020373678],"domain_scores_gemma":[0.9999372,0.000019710742,0.000013654769,0.000006554567,0.000010953671,0.000011931285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018178069,0.00019976722,0.00011236367,0.00019067875,0.00015754439,0.00041075106,0.0002146717,0.0004204205,0.0012212658],"category_scores_gemma":[0.00015820404,0.00015340082,0.00014414656,0.00008232961,0.00023063313,0.00035526566,0.00020670018,0.0004609623,0.00029369522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063607724,0.00001221253,0.00016377284,0.000034267454,0.0000021629833,0.00006375901,0.000014747612,0.00010228626,0.9968079,0.00068407314,0.000091968526,0.001959313],"study_design_scores_gemma":[0.000021029848,0.00006358233,0.0006029588,0.000004175563,0.0000066557977,0.00012649116,0.000019744377,0.0036588272,0.99432063,0.00014063348,0.0010319324,0.0000033894619],"about_ca_topic_score_codex":0.0008002525,"about_ca_topic_score_gemma":0.0005039878,"teacher_disagreement_score":0.0012212658,"about_ca_system_score_codex":0.00041785714,"about_ca_system_score_gemma":0.00027281864,"threshold_uncertainty_score":0.004085541},"labels":[],"label_agreement":null},{"id":"W2090704119","doi":"10.1007/s11095-006-9220-1","title":"In Vivo Performance of a Liposomal Vascular Contrast Agent for CT and MR-Based Image Guidance Applications","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":113,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Bracco Diagnostics","keywords":"Iohexol; In vivo; Liposome; Pharmacokinetics; Biodistribution; Gadolinium; Chemistry; Medicine; Nuclear medicine; Biomedical engineering; Pharmacology; Renal function; Internal medicine","score_opus":0.0814246757441526,"score_gpt":0.4241675524908385,"score_spread":0.3427428767466859,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090704119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906499,0.0024231046,0.0051785046,0.000121792276,0.00003948409,0.000073212184,0.0001629226,0.00010717444,0.0012440049],"genre_scores_gemma":[0.99458164,0.0006448229,0.0025651082,0.00005549507,0.000020791806,0.000033563138,0.00024448612,0.000065955726,0.0017882135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998654,0.00004635137,0.000007221962,0.00002537809,0.000017087776,0.000038559338],"domain_scores_gemma":[0.9994956,0.0002863612,0.00007090607,0.00003559694,0.00004258007,0.00006893799],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058209465,0.00039429622,0.00031097676,0.00030479342,0.00020729168,0.00046294037,0.00035429126,0.00071854214,0.0013908102],"category_scores_gemma":[0.0007870863,0.0002892265,0.00019040151,0.00018440351,0.0004170225,0.0006151241,0.00014942235,0.0005391226,0.00034927507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004958171,0.00033727006,0.00022667665,0.00009284649,0.00002198628,0.00013296906,0.00005531711,0.00043331453,0.9898363,0.00014869122,0.00014704821,0.0036095083],"study_design_scores_gemma":[0.000100140074,0.0027549108,0.00083284214,0.0000057264074,0.000061089544,0.00023882123,0.000013946051,0.0026260393,0.9926353,0.000030087782,0.000692605,0.000008592502],"about_ca_topic_score_codex":0.0013912474,"about_ca_topic_score_gemma":0.0006225977,"teacher_disagreement_score":0.0013912474,"about_ca_system_score_codex":0.00028936492,"about_ca_system_score_gemma":0.00047653407,"threshold_uncertainty_score":0.0046527386},"labels":[],"label_agreement":null},{"id":"W2090905813","doi":"10.1007/s11095-014-1506-0","title":"Dendrimer-stabilized smart-nanoparticle (DSSN) platform for targeted delivery of hydrophobic antitumor therapeutics","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Dendrimers and Hyperbranched Polymers","field":"Materials Science","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Concordia University; Commonwealth Scholarship Commission","keywords":"Cytotoxicity; Chemistry; Paclitaxel; Drug delivery; Dendrimer; Flow cytometry; Biophysics; Targeted drug delivery; Drug carrier; In vitro; MTT assay; Pharmacology; Biochemistry; Molecular biology; Cancer; Biology; Organic chemistry","score_opus":0.16501849217606473,"score_gpt":0.42524053883244783,"score_spread":0.2602220466563831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090905813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815512,0.0013642655,0.0134605225,0.00019349474,0.000057385976,0.00006229284,0.00012994932,0.000121826866,0.0030591614],"genre_scores_gemma":[0.98520225,0.0006280097,0.009467,0.0000678741,0.000014527823,0.000038162434,0.000131471,0.000012477867,0.004438266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999255,0.000008079941,0.000004940135,0.000021156782,0.0000264082,0.000013871637],"domain_scores_gemma":[0.9999454,0.000008187191,0.000015887686,0.000004370568,0.00001243284,0.000013799539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019453024,0.0002861889,0.00019024781,0.00017800649,0.00016905414,0.0002043654,0.00017401855,0.00035314893,0.000629484],"category_scores_gemma":[0.00009774364,0.00015294252,0.00015686714,0.000091197755,0.00019379029,0.00030333758,0.00025244316,0.00026900708,0.00030421367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004357679,0.00001044092,0.000039297232,0.000030409785,0.0000018084122,0.000025424639,0.00000846926,0.00024049249,0.99803096,0.0002452706,0.000048009042,0.0012759445],"study_design_scores_gemma":[0.0000066138346,0.00006374785,0.00018716355,0.0000016789443,0.0000047095464,0.000039034414,0.0000045149,0.0017348967,0.99675983,0.000029528772,0.0011649822,0.0000033373592],"about_ca_topic_score_codex":0.00043329436,"about_ca_topic_score_gemma":0.00097099866,"teacher_disagreement_score":0.000629484,"about_ca_system_score_codex":0.0005543488,"about_ca_system_score_gemma":0.0004120855,"threshold_uncertainty_score":0.0040221214},"labels":[],"label_agreement":null},{"id":"W2092470780","doi":"10.1007/s11095-014-1533-x","title":"Intestinal Uptake and Transport of Vitamin B12-loaded Soy Protein Nanoparticles","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Pinocytosis; Transcytosis; Endocytosis; Nanoparticle; Intrinsic factor; Clathrin; Caco-2; Biophysics; Chemistry; Biochemistry; Nanotechnology; Materials science; Vitamin B12; Biology; Cell","score_opus":0.17042497172335072,"score_gpt":0.4582386513181264,"score_spread":0.28781367959477566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092470780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950761,0.0010320746,0.002523328,0.00009164263,0.00003599303,0.000012356296,0.00011905797,0.000043506487,0.0010659313],"genre_scores_gemma":[0.9932678,0.00045516866,0.0017343715,0.00003723507,0.000008458973,0.000013935786,0.00022422557,0.00002329762,0.004235655],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999884,0.000016936543,0.0000059824138,0.000033753884,0.00002261586,0.00003673098],"domain_scores_gemma":[0.99993205,0.000021158658,0.000010980339,0.0000053511544,0.000020174833,0.000010287015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016110492,0.00027581688,0.00032688052,0.00013017474,0.00015179518,0.00029991756,0.00018758015,0.00034191774,0.00092276913],"category_scores_gemma":[0.00016216932,0.00017043068,0.0003150567,0.00010532737,0.00017570436,0.0003603416,0.00014926727,0.0003744485,0.00026290747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007527743,0.00003264806,0.0001612982,0.00007034899,0.000014589368,0.00005623515,0.0000485625,0.0001554584,0.99605983,0.00010358113,0.00007806174,0.0024665494],"study_design_scores_gemma":[0.000027147753,0.00042714237,0.0013157502,0.0000060448097,0.000037751037,0.00006756827,0.0000664046,0.003260747,0.9934083,0.000037687292,0.0013387619,0.000006744579],"about_ca_topic_score_codex":0.0033019013,"about_ca_topic_score_gemma":0.0019450606,"teacher_disagreement_score":0.0033019013,"about_ca_system_score_codex":0.00041303193,"about_ca_system_score_gemma":0.0002761292,"threshold_uncertainty_score":0.0065653324},"labels":[],"label_agreement":null},{"id":"W2092796790","doi":"10.1007/s11095-005-4586-z","title":"Trastuzumab and Liposomal Doxorubicin in the Treatment of MCF-7 Xenograft Tumor-Bearing Mice: Combination Does Not Affect Drug Serum Levels","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Doxorubicin; Trastuzumab; Pharmacology; Medicine; Liposome; Chemotherapy; Drug; Cancer; Breast cancer; Internal medicine; Chemistry","score_opus":0.22241735679233038,"score_gpt":0.5189544992396271,"score_spread":0.29653714244729673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092796790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946391,0.002456927,0.0007419684,0.00023726837,0.00010557113,0.000040098497,0.00017644787,0.0000842709,0.0015183921],"genre_scores_gemma":[0.9955148,0.0008447252,0.00081932277,0.00005092103,0.000040502768,0.000031942665,0.0003620543,0.000020008585,0.00231566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978215,0.00005866534,0.000015589869,0.000033511184,0.000049147693,0.00006097258],"domain_scores_gemma":[0.99982554,0.00004423002,0.00003362908,0.000025605743,0.0000137145535,0.00005738131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025401346,0.00038015604,0.00078581943,0.00029480614,0.00015177405,0.0003035447,0.00030412813,0.00040579017,0.0014630342],"category_scores_gemma":[0.0003047815,0.00024637752,0.000231796,0.00023048562,0.0002875397,0.00048459592,0.00016874139,0.0007716038,0.00029787893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016636554,0.001057986,0.0011133389,0.000107886226,0.00011341412,0.00016526146,0.000054221553,0.0006116019,0.96192497,0.00020398002,0.00062019797,0.017390572],"study_design_scores_gemma":[0.0012819648,0.014468138,0.0047797365,0.000010018847,0.00020800823,0.0005121667,0.00004054964,0.002527615,0.97149974,0.00008254514,0.0045658676,0.000023646397],"about_ca_topic_score_codex":0.00081170036,"about_ca_topic_score_gemma":0.0019242376,"teacher_disagreement_score":0.0014630342,"about_ca_system_score_codex":0.00037853,"about_ca_system_score_gemma":0.00040939593,"threshold_uncertainty_score":0.004894316},"labels":[],"label_agreement":null},{"id":"W2094686752","doi":"10.1007/s11095-010-0227-2","title":"Microneedle Pre-treatment of Human Skin Improves 5-Aminolevulininc Acid (ALA)- and 5-Aminolevulinic Acid Methyl Ester (MAL)-Induced PpIX Production for Topical Photodynamic Therapy Without Increase in Pain or Erythema","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":150,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Biotechnology and Biological Sciences Research Council; Invest Northern Ireland; Kreftforeningen","keywords":"Erythema; Photodynamic therapy; Protoporphyrin IX; Dermatology; Medicine; Chemistry; Protoporphyrin; Pharmacology; Porphyrin; Photochemistry","score_opus":0.26738824796787225,"score_gpt":0.5435916272016829,"score_spread":0.2762033792338106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094686752","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900456,0.004537769,0.001943531,0.00011088405,0.00016511689,0.00005217979,0.00017818931,0.00015529012,0.002811433],"genre_scores_gemma":[0.9942715,0.0012103663,0.001041803,0.000079452315,0.000016030359,0.000015621486,0.00014821609,0.000012212164,0.003204829],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993515,0.000008771683,0.000004498092,0.000014647471,0.000015257507,0.000021691],"domain_scores_gemma":[0.99994445,0.000018718323,0.000010005714,0.0000053434487,0.000007970483,0.000013539977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007520502,0.00030414376,0.00024945292,0.00016228594,0.00014689291,0.00014369807,0.00010852424,0.0003685668,0.0029254116],"category_scores_gemma":[0.00012597964,0.000112043,0.00023498209,0.000057466783,0.00009156356,0.00019272594,0.00011316496,0.00034813315,0.00038412394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002848575,0.00006287986,0.00003892833,0.0000359286,0.000003855155,0.000026831885,0.00000712848,0.000018481707,0.99727374,0.000013854588,0.000048678747,0.0021848334],"study_design_scores_gemma":[0.000018499997,0.0011759656,0.0015151562,0.0000037128725,0.000016693584,0.00010917159,0.00001667508,0.00010540755,0.9961778,0.000009643611,0.00084926566,0.0000019331749],"about_ca_topic_score_codex":0.0006853653,"about_ca_topic_score_gemma":0.0012288538,"teacher_disagreement_score":0.0029254116,"about_ca_system_score_codex":0.00018234574,"about_ca_system_score_gemma":0.0001555804,"threshold_uncertainty_score":0.009786546},"labels":[],"label_agreement":null},{"id":"W2096267047","doi":"10.1007/s11095-014-1315-5","title":"Improved Utilization of ADAS-Cog Assessment Data Through Item Response Theory Based Pharmacometric Modeling","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; University of California, San Diego; National Institutes of Health; Genentech; IXICO; Canadian Institutes of Health Research; University of California, Los Angeles; Servier; Innovative Medicines Initiative; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; European Federation of Pharmaceutical Industries and Associations; Medpace; Eli Lilly and Company; Bristol-Myers Squibb; European Commission; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Synarc; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Cog; Item response theory; Medicine; Statistics; Computer science; Psychometrics; Artificial intelligence; Mathematics","score_opus":0.4919992571935844,"score_gpt":0.5981011077996339,"score_spread":0.10610185060604949,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096267047","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13402268,0.0013119562,0.85696393,0.0014717223,0.00006389335,0.0010487881,0.00081995747,0.0010208248,0.0032762552],"genre_scores_gemma":[0.7673588,0.00053851196,0.2286103,0.0005321417,0.00009737712,0.0012082929,0.0010402962,0.00013236734,0.00048190323],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.8345691,0.14929655,0.0033374561,0.004502787,0.007767222,0.00052679266],"domain_scores_gemma":[0.78273106,0.18842122,0.009500952,0.013573524,0.0053747436,0.00039844363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.09270286,0.0020341887,0.0038315386,0.006873201,0.00041824073,0.0029084242,0.0019178771,0.0016417986,0.0015806863],"category_scores_gemma":[0.20644529,0.0009579093,0.0045313565,0.005307684,0.0013958758,0.0032595203,0.002315655,0.0017566368,0.0006392539],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014705441,0.0011241373,0.14107193,0.0016326,0.0065113395,0.0002709127,0.001074368,0.5243478,0.0018627354,0.013325071,0.0024120833,0.3048965],"study_design_scores_gemma":[0.00026024034,0.0013976728,0.038059603,0.00023954194,0.0007909842,0.00027576837,0.00018734811,0.92716205,0.0011990262,0.02764229,0.0026436867,0.00014180483],"about_ca_topic_score_codex":0.0026152572,"about_ca_topic_score_gemma":0.0014756275,"teacher_disagreement_score":0.09270286,"about_ca_system_score_codex":0.002216357,"about_ca_system_score_gemma":0.0024208722,"threshold_uncertainty_score":0.49026543},"labels":[],"label_agreement":null},{"id":"W2101156468","doi":"10.1007/s11095-011-0376-y","title":"Antibody-Mediated “Universal” Osteoclast Targeting Platform using Calcitonin as a Model Drug","year":2011,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Monoclonal antibody; Osteoclast; Molecular biology; Chemistry; Antibody; Western blot; In vitro; Biology; Biochemistry; Immunology","score_opus":0.20761863763927796,"score_gpt":0.45506003194722594,"score_spread":0.24744139430794798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101156468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9405282,0.0071699866,0.045819297,0.00042702744,0.00011478992,0.0002862061,0.00040421257,0.00044605942,0.0048042512],"genre_scores_gemma":[0.96723026,0.0023742868,0.025674133,0.00015764748,0.000024982497,0.00013467109,0.00040495003,0.000025217943,0.003973773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998355,0.000017503373,0.00001132877,0.000035242247,0.000060129845,0.00004038617],"domain_scores_gemma":[0.9999329,0.000007670285,0.000022035852,0.0000071255586,0.000015992438,0.000014316471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019138787,0.00037696387,0.00026508947,0.00016939105,0.000110527355,0.00025307504,0.00030484772,0.0004344095,0.00066597515],"category_scores_gemma":[0.000120801255,0.000104300525,0.00025786748,0.00015241579,0.00021953287,0.0001856094,0.0002585987,0.00043504048,0.00033236685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039445273,0.000028854263,0.00006612243,0.000071736504,0.000004847321,0.00006690646,0.0000069001567,0.00015795408,0.99727064,0.00019871752,0.000074887175,0.0020129697],"study_design_scores_gemma":[0.000023394145,0.0003416321,0.0004045879,0.0000046025666,0.000018808807,0.00032432986,0.000004427398,0.0009162411,0.9938148,0.000028285544,0.004113749,0.000005114214],"about_ca_topic_score_codex":0.00044728903,"about_ca_topic_score_gemma":0.00072519854,"teacher_disagreement_score":0.00066597515,"about_ca_system_score_codex":0.00041496416,"about_ca_system_score_gemma":0.0003424374,"threshold_uncertainty_score":0.0030108094},"labels":[],"label_agreement":null},{"id":"W2106802318","doi":"10.1023/b:pham.0000019299.01265.05","title":"In situ-Forming Pharmaceutical Organogels Based on the Self-Assembly of L-Alanine Derivatives","year":2004,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":98,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Micropharma (Canada); Université de Montréal","funders":"Canada Research Chairs","keywords":"Chemistry; Kinetics; Dextran; Ethanol; Chromatography; Alanine; Organic chemistry; Biochemistry; Amino acid","score_opus":0.11420472093553945,"score_gpt":0.43680158407018504,"score_spread":0.3225968631346456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106802318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99211156,0.0012173183,0.004049608,0.0000952504,0.00003314693,0.000014479054,0.0000789369,0.0001133725,0.0022863434],"genre_scores_gemma":[0.9959617,0.0005113446,0.002191408,0.000028654598,0.0000076134434,0.0000072114876,0.00007226444,0.000018434368,0.0012014117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995184,0.000007576457,0.0000036700717,0.000011125556,0.000010107207,0.000015620868],"domain_scores_gemma":[0.9999398,0.000015296944,0.000022013612,0.000004944136,0.000004891547,0.000013016763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010955653,0.00024689766,0.00014110115,0.00012376814,0.0001072451,0.00026269804,0.00015324951,0.00019706812,0.00062856474],"category_scores_gemma":[0.00011169899,0.0001314751,0.00018052563,0.0000676768,0.00016457072,0.00026254528,0.0001710022,0.000316268,0.00020256257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002038683,0.000004795947,0.000023773959,0.000019133233,0.0000024448905,0.000026243122,0.000010400397,0.00006644384,0.999337,0.00006786244,0.000015245937,0.00040615047],"study_design_scores_gemma":[0.0000033822578,0.000025253994,0.00018854838,0.0000013406675,0.0000041015583,0.00002666781,0.0000047945305,0.00037910885,0.99877125,0.0000120562645,0.0005819314,0.0000017425172],"about_ca_topic_score_codex":0.00016964045,"about_ca_topic_score_gemma":0.00030358206,"teacher_disagreement_score":0.00062856474,"about_ca_system_score_codex":0.00015519992,"about_ca_system_score_gemma":0.00008396849,"threshold_uncertainty_score":0.0021027327},"labels":[],"label_agreement":null},{"id":"W2107905445","doi":"10.1007/s11095-012-0825-2","title":"Decreasing Herpes Simplex Viral Infectivity in Solution by Surface-Immobilized and Suspended N,N-Dodecyl,methyl-polyethylenimine","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; McMaster University","keywords":"Infectivity; Polyethylenimine; Aqueous solution; Chemistry; Herpes simplex virus; Chromatography; Virology; Virus; Biochemistry; Biology; Organic chemistry","score_opus":0.17938838458125628,"score_gpt":0.504820411499124,"score_spread":0.32543202691786777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107905445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99166226,0.0016626992,0.004177823,0.000077254736,0.0000560513,0.000044893713,0.00004685084,0.000044413697,0.0022277592],"genre_scores_gemma":[0.9896187,0.001097776,0.00548472,0.00009703277,0.000021755293,0.000037704667,0.00013622927,0.000017861556,0.0034882096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989974,0.0000175382,0.000010654086,0.000024525403,0.000023827784,0.00002376619],"domain_scores_gemma":[0.9999107,0.00003489357,0.000015456277,0.000011192075,0.000011984007,0.00001567891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000213578,0.00031469078,0.00017877635,0.00011448403,0.00013545761,0.00032531083,0.00029297092,0.000323075,0.0007169176],"category_scores_gemma":[0.00023809225,0.00018399849,0.0002248786,0.00009880351,0.00020044245,0.00024447907,0.00017101165,0.00043765057,0.00025338965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044794295,0.000017955274,0.000035294193,0.00002104484,0.0000022578192,0.000008198022,0.000006679007,0.000016785467,0.9990972,0.000028814688,0.0000076369315,0.0007133027],"study_design_scores_gemma":[0.000008229296,0.00013225543,0.00041738857,0.0000026250386,0.000005757024,0.000017998862,0.000004797735,0.00027219165,0.99881566,0.000010126774,0.00031148974,0.0000014936907],"about_ca_topic_score_codex":0.00043817566,"about_ca_topic_score_gemma":0.00080320146,"teacher_disagreement_score":0.0007169176,"about_ca_system_score_codex":0.00021009774,"about_ca_system_score_gemma":0.00027248956,"threshold_uncertainty_score":0.0023983717},"labels":[],"label_agreement":null},{"id":"W2126777024","doi":"10.1007/s11095-012-0946-7","title":"Transdermal Delivery of Molecules is Limited by Full Epidermis, Not Just Stratum Corneum","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":214,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; McMaster University; Eli Lilly and Company","keywords":"Stratum corneum; Transdermal; Permeability (electromagnetism); Epidermis (zoology); Corneocyte; Chemistry; Dermis; Human skin; Biophysics; Biology; Pharmacology; Biochemistry; Anatomy; Membrane","score_opus":0.4289729679705411,"score_gpt":0.5562753947471799,"score_spread":0.12730242677663883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126777024","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.67821145,0.17392716,0.10718092,0.0060885567,0.00096166605,0.00025115765,0.00064695935,0.0011119562,0.03162014],"genre_scores_gemma":[0.9145441,0.052306272,0.019306941,0.0016904685,0.00015813194,0.00013826015,0.00036380388,0.00015339644,0.011338695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991079,0.00017193927,0.000061610444,0.00018333377,0.00038140902,0.00009385856],"domain_scores_gemma":[0.999057,0.0003309045,0.00021312744,0.00011276757,0.00021304899,0.00007305137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007720793,0.0005692038,0.00096043485,0.00048990105,0.00041796354,0.0018929706,0.00047108368,0.000896033,0.0019513773],"category_scores_gemma":[0.0009199975,0.00039215,0.0005613945,0.00027241057,0.0007621602,0.0032746552,0.0010735769,0.001685581,0.0014079751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088629255,0.000019199015,0.0002553359,0.0003428771,0.00002568767,0.000127912,0.000057528236,0.00009017801,0.98551244,0.0014427697,0.00027489167,0.011762546],"study_design_scores_gemma":[0.00003539418,0.00046166568,0.006254283,0.00016350426,0.00013470135,0.0023212396,0.0003227212,0.0015541764,0.9542989,0.0029868088,0.03143488,0.00003172581],"about_ca_topic_score_codex":0.00075228064,"about_ca_topic_score_gemma":0.00071200385,"teacher_disagreement_score":0.0019513773,"about_ca_system_score_codex":0.00061245303,"about_ca_system_score_gemma":0.00065787364,"threshold_uncertainty_score":0.0065279603},"labels":[],"label_agreement":null},{"id":"W2132071446","doi":"10.1023/b:pham.0000003390.51761.3d","title":"Recommendations for the Bioanalytical Method Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Macromolecules","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":614,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Greenfield Research (Canada)","funders":"American Association of Pharmaceutical Scientists; Eli Lilly and Company","keywords":"Bioanalysis; Acceptance testing; Computer science; Process (computing); Biochemical engineering; Computational biology; Chemistry; Engineering; Chromatography; Biology; Software engineering","score_opus":0.35160811898357314,"score_gpt":0.574760009449789,"score_spread":0.22315189046621586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132071446","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.042028844,0.024597602,0.5734483,0.2025473,0.0134812975,0.01734714,0.0088701425,0.01199235,0.10568698],"genre_scores_gemma":[0.032874238,0.006191528,0.87848264,0.034245625,0.0011951857,0.007730473,0.0050346847,0.0011295574,0.03311605],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9300995,0.026608495,0.013166992,0.0023485362,0.025443215,0.0023333477],"domain_scores_gemma":[0.6884523,0.073014855,0.020218302,0.021421174,0.18894674,0.00794663],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06292682,0.003165574,0.0030824025,0.008826981,0.0063357507,0.004551926,0.010385698,0.020795584,0.0069878194],"category_scores_gemma":[0.12570685,0.0038325712,0.0048509473,0.0048540053,0.0040446566,0.00320366,0.002169124,0.013419433,0.01201612],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013485746,0.00366337,0.014907484,0.0055082794,0.00071262824,0.0027916946,0.0032120396,0.007392977,0.08521853,0.011070852,0.4862828,0.37789077],"study_design_scores_gemma":[0.0011004311,0.0017757721,0.03522394,0.01066336,0.0024406114,0.00440696,0.0028797635,0.014471462,0.15120159,0.017633036,0.75726086,0.00094216206],"about_ca_topic_score_codex":0.034897897,"about_ca_topic_score_gemma":0.04409604,"teacher_disagreement_score":0.06292682,"about_ca_system_score_codex":0.0042122346,"about_ca_system_score_gemma":0.02473309,"threshold_uncertainty_score":0.33279276},"labels":[],"label_agreement":null},{"id":"W2133744014","doi":"10.1007/s11095-008-9673-5","title":"Multifunctional Polymeric Micelles for Enhanced Intracellular Delivery of Doxorubicin to Metastatic Cancer Cells","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":108,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Micelle; Doxorubicin; Chemistry; Cytotoxicity; Drug delivery; Intracellular; Internalization; Biophysics; Drug carrier; Ethylene oxide; Biochemistry; Receptor; Copolymer; In vitro; Organic chemistry; Medicine; Biology; Polymer; Chemotherapy; Aqueous solution","score_opus":0.17380485467218096,"score_gpt":0.4339368233264323,"score_spread":0.26013196865425137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133744014","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9489583,0.009246085,0.036119416,0.00044819643,0.00013554827,0.00015003324,0.00016829661,0.0002562998,0.0045179874],"genre_scores_gemma":[0.9821599,0.0023667375,0.011102021,0.000099013385,0.000023775996,0.000062029816,0.00009277253,0.000043831336,0.0040498716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999236,0.000013936597,0.0000062923773,0.00001803275,0.00001624943,0.000021852386],"domain_scores_gemma":[0.99993944,0.000012710983,0.000016960903,0.000004351668,0.000013531867,0.0000130266935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027118178,0.0003211067,0.0001868652,0.00020717214,0.0001372003,0.0002738394,0.00017425466,0.00034342636,0.0007196952],"category_scores_gemma":[0.0001937151,0.00017088956,0.00016965048,0.00009345662,0.00017121478,0.00039594152,0.00028001817,0.0003567289,0.00031044352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007845065,0.000014895376,0.000028402377,0.000046577516,0.0000035913058,0.00003399783,0.0000218258,0.00016350861,0.99636394,0.00034161293,0.000084321924,0.0028189225],"study_design_scores_gemma":[0.000030804687,0.0001802534,0.00024899276,0.000006849818,0.000014654085,0.00012085287,0.000007341938,0.0016315108,0.99402446,0.00004894698,0.0036792073,0.0000061621117],"about_ca_topic_score_codex":0.00065111247,"about_ca_topic_score_gemma":0.0010274755,"teacher_disagreement_score":0.0007196952,"about_ca_system_score_codex":0.00047363978,"about_ca_system_score_gemma":0.00022500879,"threshold_uncertainty_score":0.0034364462},"labels":[],"label_agreement":null},{"id":"W2135779742","doi":"10.1007/s11095-007-9444-8","title":"Molecular Mobility, Thermodynamics and Stability of Griseofulvin’s Ultraviscous and Glassy States from Dynamic Heat Capacity","year":2007,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Centre National de la Recherche Scientifique; Pfizer","keywords":"Griseofulvin; Heat capacity; Crystallization; Thermodynamics; Relaxation (psychology); Extrapolation; Chemistry; Differential scanning calorimetry; Glass transition; Calorimetry; Materials science; Organic chemistry; Polymer; Physics","score_opus":0.20932021262826753,"score_gpt":0.5027343147066827,"score_spread":0.29341410207841523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135779742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949767,0.00091231015,0.0032431802,0.00010362945,0.0000083508085,0.000005126129,0.00011379764,0.000022631548,0.0006143406],"genre_scores_gemma":[0.99894434,0.00023876238,0.00038664293,0.000011383537,0.0000052157407,0.000004821219,0.00012347412,0.000008295651,0.00027696128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998423,0.000024955392,0.0000075212615,0.000033834014,0.000052744985,0.00003853856],"domain_scores_gemma":[0.9996674,0.00017583215,0.0000739178,0.000027924218,0.000035506895,0.000019469053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041224263,0.00022058407,0.00012909067,0.0006052122,0.000258471,0.00035944523,0.00041376118,0.0002959698,0.0011466602],"category_scores_gemma":[0.0010170508,0.00021686805,0.00029489948,0.00031650419,0.00097622664,0.0006606612,0.00033389288,0.00074150093,0.00016024726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028771276,0.000030361392,0.0031198773,0.000055581742,0.000022728314,0.00011331486,0.00050770293,0.002553082,0.9813013,0.0039151437,0.00015979758,0.007933567],"study_design_scores_gemma":[0.000009565794,0.000101137935,0.009190911,0.000008936825,0.0000138226305,0.0000994074,0.000113685,0.0121313045,0.97630966,0.0010805762,0.00090909493,0.000031839394],"about_ca_topic_score_codex":0.0030718513,"about_ca_topic_score_gemma":0.0014002256,"teacher_disagreement_score":0.0030718513,"about_ca_system_score_codex":0.0007133197,"about_ca_system_score_gemma":0.0002347069,"threshold_uncertainty_score":0.0061079264},"labels":[],"label_agreement":null},{"id":"W2138151814","doi":"10.1023/a:1013085811044","title":"Pharmacokinetics of Differently Designed Immunoliposome Formulations in Rats with Or Without Hepatic Colon Cancer Metastases","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"KWF Kankerbestrijding; Rijksuniversiteit Groningen","keywords":"Liposome; Pharmacokinetics; Pharmacology; Antibody; In vivo; Monoclonal antibody; PEG ratio; Colorectal cancer; Prodrug; Chemistry; Medicine; Cancer; Cancer research; Biochemistry; Immunology; Internal medicine; Biology","score_opus":0.17408039784173943,"score_gpt":0.4621107419890137,"score_spread":0.28803034414727424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138151814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952213,0.00088686426,0.0019667202,0.00015344529,0.00012581913,0.000051979005,0.00056546926,0.00013009278,0.00089819636],"genre_scores_gemma":[0.99082774,0.0010427706,0.0017130213,0.0001107847,0.000055468183,0.000108563836,0.00054366933,0.00007399973,0.0055238893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998252,0.00002297679,0.000008923614,0.000047388097,0.00002359048,0.00007198372],"domain_scores_gemma":[0.9997577,0.000057757876,0.00006665196,0.000027713644,0.000026528101,0.000063635416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027032138,0.00062363996,0.00060328975,0.0003913467,0.00019767108,0.00047105647,0.00027024947,0.0005972602,0.0018101403],"category_scores_gemma":[0.00041394442,0.00036760935,0.0003963046,0.00023247462,0.00061120366,0.0008274805,0.00012174128,0.0012158372,0.0004896076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03627124,0.0014100005,0.0010585184,0.00015113362,0.0000869439,0.00018423672,0.000108464505,0.0016339952,0.9420345,0.00039122443,0.00057533314,0.016094437],"study_design_scores_gemma":[0.0006558475,0.0143841235,0.0041084476,0.0000091722395,0.00020140919,0.00015571089,0.00007706866,0.0037416492,0.9747951,0.00019776802,0.0016264713,0.00004727351],"about_ca_topic_score_codex":0.0024197649,"about_ca_topic_score_gemma":0.002353028,"teacher_disagreement_score":0.0024197649,"about_ca_system_score_codex":0.00063470803,"about_ca_system_score_gemma":0.00077178655,"threshold_uncertainty_score":0.0060554743},"labels":[],"label_agreement":null},{"id":"W2140845729","doi":"10.1007/s11095-012-0942-y","title":"Role of Drug Efflux and Uptake Transporters in Atazanavir Intestinal Permeability and Drug-Drug Interactions","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Atazanavir; Pharmacology; Ritonavir; Chemistry; P-glycoprotein; Efflux; Drug; Protease inhibitor (pharmacology); Transporter; Ileum; Protease; Intestinal permeability; Biochemistry; Biology; Enzyme; Immunology; Multiple drug resistance; Antibiotics","score_opus":0.09085452363592117,"score_gpt":0.43438486384604125,"score_spread":0.3435303402101201,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140845729","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7615587,0.20619138,0.009762909,0.0064099147,0.00018214111,0.00009420832,0.00025281278,0.00011718279,0.015430686],"genre_scores_gemma":[0.95926255,0.034608714,0.0020927973,0.00037149194,0.00016877441,0.000029885263,0.00010791583,0.000017821054,0.0033399824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938726,0.00029991206,0.000048884278,0.00005036643,0.00011760035,0.00009597584],"domain_scores_gemma":[0.9992519,0.00032983813,0.00017601569,0.000031860003,0.00014908983,0.00006112517],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011150765,0.00050426356,0.00096504256,0.00077421404,0.0005190028,0.0022799617,0.0005730063,0.0011664128,0.0024946765],"category_scores_gemma":[0.0013444717,0.0003470739,0.00061587733,0.0005897251,0.0007389988,0.0027998989,0.0004936179,0.0010858248,0.000489261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012122631,0.0018241028,0.10500114,0.0038544475,0.001456369,0.01202968,0.0013295542,0.01419078,0.42889962,0.08964338,0.00557998,0.32406834],"study_design_scores_gemma":[0.0011842131,0.006959104,0.33676353,0.0008072959,0.0024261011,0.04193028,0.003719411,0.105386,0.3050079,0.05783984,0.1375168,0.00045950702],"about_ca_topic_score_codex":0.0020246597,"about_ca_topic_score_gemma":0.0016427877,"teacher_disagreement_score":0.0024946765,"about_ca_system_score_codex":0.0011047943,"about_ca_system_score_gemma":0.0008273977,"threshold_uncertainty_score":0.008345485},"labels":[],"label_agreement":null},{"id":"W2143645910","doi":"10.1007/s11095-012-0935-x","title":"Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":93,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"National Institute of Environmental Health Sciences; University of California, San Diego; National Institute of General Medical Sciences; University of Tokyo","keywords":"DrugBank; Quantitative structure–activity relationship; Transporter; Random forest; Virtual screening; Drug discovery; Cheminformatics; Drug; Chemistry; Profiling (computer programming); Computational biology; Pharmacology; Computer science; Machine learning; Biology; Bioinformatics; Biochemistry","score_opus":0.2960278838338332,"score_gpt":0.5184981495419329,"score_spread":0.22247026570809963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143645910","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1852497,0.013054165,0.048187118,0.0015122826,0.00013980774,0.00061934587,0.72151315,0.02127249,0.008451917],"genre_scores_gemma":[0.31297645,0.0073973644,0.057200823,0.0007059594,0.00007801856,0.0009230173,0.6157985,0.0011771349,0.003742797],"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99980503,0.000063330874,0.00002357415,0.00003720652,0.000055838686,0.000015011387],"domain_scores_gemma":[0.9996164,0.000177027,0.000041750314,0.00007287727,0.000057496814,0.000034417266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005976266,0.0010450234,0.0019063805,0.00085556385,0.00026475784,0.00076809234,0.001859238,0.0009770744,0.011744036],"category_scores_gemma":[0.0019809946,0.00039131293,0.0011134801,0.001534283,0.00017047781,0.00046438118,0.00048240527,0.0006578423,0.0038222151],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013443839,0.002238763,0.019629922,0.015701681,0.0041472553,0.0022756346,0.00026356932,0.16033486,0.06070708,0.011827987,0.41326436,0.29616508],"study_design_scores_gemma":[0.012186262,0.0030214924,0.02768564,0.0005924882,0.0056095896,0.0047706687,0.00025265396,0.4758442,0.05873706,0.009460328,0.40149298,0.00034661128],"about_ca_topic_score_codex":0.0060463324,"about_ca_topic_score_gemma":0.0070952056,"teacher_disagreement_score":0.011744036,"about_ca_system_score_codex":0.00045237923,"about_ca_system_score_gemma":0.0018330083,"threshold_uncertainty_score":0.039287686},"labels":[],"label_agreement":null},{"id":"W2149978263","doi":"10.1007/s11095-008-9692-2","title":"Preparation of BMP-2 Containing Bovine Serum Albumin (BSA) Nanoparticles Stabilized by Polymer Coating","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":102,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"","keywords":"Bovine serum albumin; Nanoparticle; Chemistry; Coating; Serum albumin; Dosage form; Polymer; Microparticle; Drug carrier; Nuclear chemistry; Chromatography; Polymer chemistry; Chemical engineering; Drug delivery; Biochemistry; Materials science; Organic chemistry; Nanotechnology","score_opus":0.1250198027964521,"score_gpt":0.42679648194032627,"score_spread":0.3017766791438742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149978263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96700746,0.0013620721,0.027979081,0.00011399217,0.000098616816,0.00020911713,0.00028528756,0.00024799217,0.0026964569],"genre_scores_gemma":[0.96243155,0.0010125511,0.03090673,0.00010696409,0.000027160659,0.00017753894,0.0005052636,0.0001179028,0.00471427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998318,0.000018816707,0.000020816102,0.000042930966,0.00005345847,0.00003210334],"domain_scores_gemma":[0.9998518,0.000037503876,0.000034793688,0.00001559811,0.000035385045,0.000024874393],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030625187,0.00053624593,0.00040172035,0.00031644988,0.00018361169,0.00025859624,0.0002999925,0.0004836623,0.0009812298],"category_scores_gemma":[0.00027251578,0.0003091316,0.0003304043,0.00021426189,0.00020627749,0.00021946046,0.00021702256,0.00044465813,0.0004808155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039562943,0.000008842094,0.000025793028,0.000026139061,0.0000037236246,0.000018405673,0.000008102949,0.00007899361,0.99923694,0.00003853272,0.000013707356,0.0005012187],"study_design_scores_gemma":[0.00000924381,0.000045681805,0.00021713761,0.00000201577,0.000006444683,0.000028983864,0.0000024554374,0.0005590717,0.99860317,0.000010237812,0.00051269773,0.0000029575074],"about_ca_topic_score_codex":0.00050030963,"about_ca_topic_score_gemma":0.0007282825,"teacher_disagreement_score":0.0009812298,"about_ca_system_score_codex":0.00024516883,"about_ca_system_score_gemma":0.00021103109,"threshold_uncertainty_score":0.0032826066},"labels":[],"label_agreement":null},{"id":"W2158213155","doi":"10.1007/s11095-004-9010-6","title":"Selective Downregulation of Hepatic Cytochrome P450 Expression and Activity in a Rat Model of Inflammatory Pain","year":2005,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada); Université de Montréal","funders":"","keywords":"CYP2E1; Downregulation and upregulation; Cytochrome P450; Pharmacology; Chemistry; Inflammation; Endocrinology; Messenger RNA; Pharmacokinetics; Internal medicine; Medicine; Metabolism; Biochemistry","score_opus":0.24672603893382727,"score_gpt":0.5226125022133294,"score_spread":0.27588646327950217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158213155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956358,0.00095310446,0.0023163157,0.0002138178,0.000048809765,0.000039439245,0.00015846673,0.00007877951,0.0005554602],"genre_scores_gemma":[0.9950806,0.0009824913,0.0013405022,0.000059696144,0.000027226977,0.000061207684,0.00022071098,0.0000200424,0.0022074657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997552,0.000048480455,0.000012421315,0.00003992913,0.000049314218,0.00009461194],"domain_scores_gemma":[0.9997042,0.000042612155,0.00008922938,0.000056809622,0.000027744896,0.00007931709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028396782,0.00068298506,0.0006423983,0.0007739109,0.00031903049,0.0003171802,0.00031301484,0.0004014826,0.0019472102],"category_scores_gemma":[0.00025777653,0.0003364346,0.00044578596,0.00038728726,0.00083607517,0.00042684644,0.00019296187,0.0013817331,0.00032339426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005495453,0.000804582,0.00045446638,0.00005969013,0.00001993634,0.00025424626,0.00003449296,0.00012290562,0.9878477,0.00021678173,0.0001224687,0.004567318],"study_design_scores_gemma":[0.00025467694,0.0070383344,0.0061413655,0.000009845756,0.000088628876,0.00057034136,0.00009392965,0.0008818877,0.9842017,0.00014366281,0.00056321145,0.000012434231],"about_ca_topic_score_codex":0.0010010106,"about_ca_topic_score_gemma":0.0019836635,"teacher_disagreement_score":0.0019472102,"about_ca_system_score_codex":0.00041224758,"about_ca_system_score_gemma":0.00043250425,"threshold_uncertainty_score":0.006514132},"labels":[],"label_agreement":null},{"id":"W2163708010","doi":"10.1007/s11095-009-9875-5","title":"PLGA and PHBV Microsphere Formulations and Solid-State Characterization: Possible Implications for Local Delivery of Fusidic Acid for the Treatment and Prevention of Orthopaedic Infections","year":2009,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fusidic acid; Microsphere; PLGA; Drug delivery; Delivery system; Medicine; Chemistry; Biomedical engineering; Nanotechnology; Materials science; Biology; Biochemistry; Bacteria; Staphylococcus aureus; In vitro; Chemical engineering","score_opus":0.23443348737171854,"score_gpt":0.5394556207653352,"score_spread":0.3050221333936166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163708010","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9614879,0.002393654,0.034330476,0.00019159068,0.000021421838,0.00004421639,0.0002206148,0.000059939965,0.0012501578],"genre_scores_gemma":[0.9916808,0.00060175697,0.0063882614,0.000028179946,0.0000071772592,0.000016922833,0.00011919669,0.00001609579,0.0011415927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998691,0.000032402906,0.000008477264,0.000024738792,0.000039643055,0.000025528881],"domain_scores_gemma":[0.99982363,0.0000789962,0.00004177988,0.000012663088,0.000030324662,0.0000126881705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003192739,0.00022001841,0.00018291814,0.00018115604,0.00019675156,0.00033891984,0.0001316019,0.00031184545,0.00080198847],"category_scores_gemma":[0.00044175313,0.00014266428,0.00016973639,0.00014956719,0.00029674935,0.00049537164,0.00013186771,0.00035627672,0.00011976201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008459072,0.0000083549285,0.00012626272,0.000019415123,0.0000022241647,0.00001589981,0.000019692561,0.00017260882,0.99731857,0.00016434972,0.0000116634965,0.0020562434],"study_design_scores_gemma":[0.0000033066692,0.00012529832,0.0007816506,0.0000020989464,0.000006153587,0.00005523928,0.000019293786,0.0009829077,0.997528,0.00008135112,0.0004104391,0.0000042618026],"about_ca_topic_score_codex":0.0016196558,"about_ca_topic_score_gemma":0.0021398938,"teacher_disagreement_score":0.0016196558,"about_ca_system_score_codex":0.00033335792,"about_ca_system_score_gemma":0.0002897904,"threshold_uncertainty_score":0.003220439},"labels":[],"label_agreement":null},{"id":"W2163758521","doi":"10.1023/a:1026179132599","title":"Sensitization of Cells Overexpressing Multidrug-Resistant Proteins by Pluronic P85","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Supratek Pharma (Canada)","funders":"National Cancer Institute; National Institutes of Health; Wellcome Trust","keywords":"Multidrug resistance-associated protein 2; Glutathione; Vinblastine; Cytotoxicity; Doxorubicin; Pharmacology; Multiple drug resistance; Intracellular; Chemistry; Sensitization; Transfection; ATP-binding cassette transporter; Biochemistry; Chemotherapy; In vitro; Biology; Transporter; Enzyme; Immunology","score_opus":0.0929013536587075,"score_gpt":0.4213124511922604,"score_spread":0.3284110975335529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163758521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935063,0.0006971305,0.00236546,0.00020066542,0.000078405865,0.000070686074,0.0003207909,0.00008995701,0.0026705551],"genre_scores_gemma":[0.99422944,0.0004969516,0.0011157634,0.00006333541,0.000015847945,0.000035965455,0.00045141668,0.000022364473,0.0035689077],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961805,0.000083422805,0.000042130036,0.000050548042,0.00008981307,0.00011587822],"domain_scores_gemma":[0.99968636,0.00012607893,0.00004470498,0.000074902455,0.0000358827,0.00003207095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035392345,0.00048734885,0.0007122135,0.00028719942,0.00027684067,0.00047533074,0.00025076157,0.00048402854,0.0019683703],"category_scores_gemma":[0.00025604403,0.00023597645,0.0006088124,0.0004595794,0.00032038777,0.00043883905,0.00031659383,0.0011752303,0.0005754231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000429547,0.00014639848,0.00016649779,0.000050868963,0.000011871194,0.00007899874,0.00008856995,0.00020233823,0.9967596,0.00037265755,0.00009264753,0.0016001044],"study_design_scores_gemma":[0.000028006181,0.00052337634,0.0013117911,0.0000031803556,0.000013016025,0.00009044774,0.000034768633,0.0008875333,0.99611413,0.00003788875,0.0009517948,0.0000039751753],"about_ca_topic_score_codex":0.0011707558,"about_ca_topic_score_gemma":0.0009026187,"teacher_disagreement_score":0.0019683703,"about_ca_system_score_codex":0.00037775384,"about_ca_system_score_gemma":0.00026210208,"threshold_uncertainty_score":0.0065848827},"labels":[],"label_agreement":null},{"id":"W2168656522","doi":"10.1007/s11095-008-9791-0","title":"Naringenin-Loaded Nanoparticles Improve the Physicochemical Properties and the Hepatoprotective Effects of Naringenin in Orally-Administered Rats with CCl4-Induced Acute Liver Failure","year":2008,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":233,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Science Council","keywords":"Naringenin; Pharmacology; Chemistry; Antioxidant; Bioavailability; Carbon tetrachloride; Lipid peroxidation; Oral administration; In vivo; CCL4; Oxidative stress; Biochemistry; Medicine; Flavonoid; Biology; Organic chemistry","score_opus":0.27008312181929434,"score_gpt":0.43625017587421244,"score_spread":0.1661670540549181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168656522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973686,0.00061151333,0.001353114,0.000060798364,0.000026032403,0.000009526794,0.000054016426,0.000049647642,0.00046682742],"genre_scores_gemma":[0.99688077,0.00037755675,0.0013172856,0.000041202034,0.000012463247,0.000012765036,0.00008383423,0.000021053214,0.001253166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999951,0.0000064394144,0.0000043376644,0.000011769738,0.000014176773,0.000012346336],"domain_scores_gemma":[0.9999356,0.000009430015,0.000023159713,0.000006435202,0.0000102000795,0.000015132644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008878419,0.00032617102,0.00031526163,0.00014976611,0.000116304866,0.00015234067,0.0001134725,0.00026235112,0.0007723914],"category_scores_gemma":[0.000117041265,0.00015874593,0.00019981751,0.000063081345,0.00018360085,0.00028121943,0.00012250252,0.00044001738,0.00018406833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015690092,0.00001793257,0.000039401402,0.000015221512,0.0000039837973,0.00001090765,0.0000051558645,0.0000563474,0.9988832,0.000021742513,0.000013290284,0.0007759636],"study_design_scores_gemma":[0.000021399075,0.00035154255,0.0013531398,0.0000023557407,0.00002907095,0.000056097746,0.0000093008985,0.00070315955,0.9967914,0.00003673252,0.00064180174,0.0000039163974],"about_ca_topic_score_codex":0.00033867452,"about_ca_topic_score_gemma":0.00054395886,"teacher_disagreement_score":0.0007723914,"about_ca_system_score_codex":0.0001476663,"about_ca_system_score_gemma":0.00012417905,"threshold_uncertainty_score":0.002583921},"labels":[],"label_agreement":null},{"id":"W2171897480","doi":"10.1007/s11095-010-0063-4","title":"Erratum to: Movement of Heparins Across Rat Gastric Mucosa is Dependent on Molecular Weight and pH","year":2010,"lang":"en","type":"erratum","venue":"Pharmaceutical Research","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Gastric mucosa; Pharmacology; Chemistry; Medicine; Biochemistry; Stomach","score_opus":0.08393570332763847,"score_gpt":0.446994008363653,"score_spread":0.36305830503601455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171897480","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021197812,0.008860601,0.0011003648,0.03131588,0.95315474,0.000043151787,0.000505278,0.0002160433,0.0026841369],"genre_scores_gemma":[0.05139667,0.07404774,0.018128013,0.10117177,0.38991973,0.0003805192,0.004743996,0.0011170256,0.35909456],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984316,0.00019502382,0.00046138675,0.00017176717,0.00059025915,0.00014997396],"domain_scores_gemma":[0.9921191,0.0027695324,0.000823502,0.00058895315,0.0032329839,0.00046590655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019403046,0.0034960883,0.0023251448,0.0034228845,0.0024715036,0.001427103,0.0030998294,0.0065648276,0.017063847],"category_scores_gemma":[0.012898209,0.0015944056,0.0019981244,0.0023492118,0.0019458317,0.0022176881,0.0009669736,0.005586968,0.016665015],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011286974,0.00014108268,0.0005666696,0.0014209608,0.0001227864,0.0034977708,0.00007387964,0.00025985154,0.003802193,0.0010871495,0.957647,0.030251898],"study_design_scores_gemma":[0.0002117892,0.000698412,0.0067485925,0.0005914796,0.000536265,0.005097368,0.0003014475,0.0008372544,0.01231841,0.0013677172,0.9711151,0.00017613337],"about_ca_topic_score_codex":0.006249803,"about_ca_topic_score_gemma":0.007892433,"teacher_disagreement_score":0.017063847,"about_ca_system_score_codex":0.0023023775,"about_ca_system_score_gemma":0.002254538,"threshold_uncertainty_score":0.057084262},"labels":[],"label_agreement":null},{"id":"W2172163728","doi":"10.1023/a:1016161001013","title":"Tissue distribution of [14C]sucrose octasulfate following oral administration to rats.","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Chemistry; Stomach; Urine; Kidney; Ileum; Sodium; Spleen; Pharmacokinetics; Pharmacology; Feces; Endocrinology; Internal medicine; Medicine; Biochemistry; Biology","score_opus":0.15955841996127387,"score_gpt":0.4798332151615531,"score_spread":0.32027479520027924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2172163728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803262,0.006244967,0.003917538,0.000391545,0.00028169685,0.00010640688,0.0017337942,0.0003958717,0.006602107],"genre_scores_gemma":[0.9646015,0.0077083376,0.003261812,0.00014540438,0.000119488715,0.00013578084,0.0019567334,0.00013544547,0.021935526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982953,0.000026631506,0.000005958317,0.000039271414,0.000029357077,0.00006925113],"domain_scores_gemma":[0.9996419,0.00005135003,0.00010054788,0.00003782921,0.00006402724,0.00010430308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002169729,0.0012867673,0.0007458765,0.001021004,0.0004613382,0.0006262694,0.00044366697,0.0007965523,0.0032133395],"category_scores_gemma":[0.00021271165,0.00059388106,0.0005268355,0.0007070657,0.0009259815,0.0008161504,0.00017384806,0.0014186692,0.00080246775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018701874,0.0005152203,0.00069517497,0.00021845839,0.00009508455,0.00031033452,0.00009742337,0.00056811085,0.9667888,0.00060847116,0.00045486068,0.010946174],"study_design_scores_gemma":[0.00019833376,0.0061853942,0.0043924535,0.000029143346,0.0002074035,0.00022291673,0.00014152663,0.0011181108,0.984584,0.00023536055,0.0026529387,0.000032494707],"about_ca_topic_score_codex":0.0078737335,"about_ca_topic_score_gemma":0.012077271,"teacher_disagreement_score":0.0078737335,"about_ca_system_score_codex":0.00096500356,"about_ca_system_score_gemma":0.0016469761,"threshold_uncertainty_score":0.015655816},"labels":[],"label_agreement":null},{"id":"W2172734873","doi":"10.1007/s11095-015-1818-8","title":"Controlled Release from Zein Matrices: Interplay of Drug Hydrophobicity and pH","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Proteins in Food Systems","field":"Agricultural and Biological Sciences","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Newfoundland and Labrador; Foundation for Fundamental Research on Matter; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Stichting voor Fundamenteel Onderzoek der Materie","keywords":"Excipient; Swelling; Chemistry; Drug delivery; Kinetics; Controlled release; Drug; Dissolution; Isoelectric point; Chromatography; Crystallinity; Dosage form; Extrusion; Liberation; Chemical engineering; Pharmacology; Organic chemistry; Materials science; Biochemistry; In vitro; Crystallography","score_opus":0.18645154520105295,"score_gpt":0.4280847102635932,"score_spread":0.24163316506254023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2172734873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956929,0.0010005598,0.00263936,0.000038540336,0.0000048852357,0.000022409784,0.00005216855,0.000020835236,0.0005283517],"genre_scores_gemma":[0.9976211,0.0006689663,0.0013785826,0.000011075864,0.0000034241962,0.0000096267595,0.000038153594,0.0000067116844,0.00026218145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999161,0.000018187224,0.0000054364095,0.00001836812,0.000025342737,0.000016481888],"domain_scores_gemma":[0.9998215,0.000073639705,0.00007064443,0.000009234898,0.00001293108,0.000012160364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001912423,0.00022936649,0.00016919266,0.00011679521,0.000099782046,0.0002805122,0.00009268803,0.00015359477,0.00051938085],"category_scores_gemma":[0.00027780255,0.00012115934,0.00015265068,0.00010332604,0.0002474647,0.0003794126,0.0001708495,0.0002909603,0.00013351341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009259819,0.000008931936,0.00015769985,0.00003809057,0.0000038087862,0.00003520562,0.000013402262,0.0001309213,0.9986601,0.000031263946,0.000005950962,0.00082199834],"study_design_scores_gemma":[0.0000120966415,0.00022473354,0.0021703986,0.0000049966225,0.000009789388,0.00007822386,0.0000132400155,0.001546055,0.99545336,0.000026513828,0.00045631008,0.0000042925085],"about_ca_topic_score_codex":0.0002677908,"about_ca_topic_score_gemma":0.00045020334,"teacher_disagreement_score":0.00051938085,"about_ca_system_score_codex":0.00015334788,"about_ca_system_score_gemma":0.0001068896,"threshold_uncertainty_score":0.001737535},"labels":[],"label_agreement":null},{"id":"W2218418421","doi":"10.1007/s11095-015-1820-1","title":"Multivariate Analysis of Effects of Asthmatic Patient Respiratory Profiles on the In Vitro Performance of a Reservoir Multidose and a Capsule-Based Dry Powder Inhaler","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Chiesi Farmaceutici","keywords":"Dry-powder inhaler; Inhaler; Capsule; Respiratory system; Pharmaceutical technology; Asthma; Multivariate analysis; Medicine; Multivariate statistics; Dosage form; Chromatography; In vitro; Pharmacology; Anesthesia; Chemistry; Internal medicine; Biology; Mathematics","score_opus":0.144609510725455,"score_gpt":0.42314827031398494,"score_spread":0.2785387595885299,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2218418421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968951,0.00031822483,0.0022722569,0.000018218007,0.000012445277,0.00003491839,0.00021970615,0.000019894364,0.00020929269],"genre_scores_gemma":[0.998252,0.000113529255,0.0011531614,0.000011380031,0.0000074695436,0.0000243816,0.0002683748,0.0000075052035,0.00016207738],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984189,0.0006538573,0.0001089398,0.00032245368,0.00039300285,0.000102896316],"domain_scores_gemma":[0.9972893,0.0017147269,0.00042267848,0.00025443558,0.00018058073,0.00013838014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016272538,0.0004133898,0.0007695606,0.0003380964,0.00012368083,0.00059075037,0.00017265305,0.0002981267,0.0014015076],"category_scores_gemma":[0.0029612686,0.00009081495,0.00067520456,0.00029205895,0.00027574116,0.00022157162,0.00028522575,0.00033032717,0.000187477],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029383335,0.0027102446,0.3829751,0.00071806385,0.002049731,0.00044903246,0.0005854332,0.010102219,0.48524338,0.00021711078,0.00040103876,0.08516531],"study_design_scores_gemma":[0.000098904165,0.02667793,0.7767996,0.000025378222,0.0011489996,0.0006603425,0.00038012135,0.029059306,0.16367401,0.0001028165,0.001309807,0.00006264145],"about_ca_topic_score_codex":0.00029227455,"about_ca_topic_score_gemma":0.00016742111,"teacher_disagreement_score":0.0016272538,"about_ca_system_score_codex":0.00015920098,"about_ca_system_score_gemma":0.00022319898,"threshold_uncertainty_score":0.008605838},"labels":[],"label_agreement":null},{"id":"W2233790834","doi":"10.1007/s11095-015-1854-4","title":"A Simple and Improved Active Loading Method to Efficiently Encapsulate Staurosporine into Lipid-Based Nanoparticles for Enhanced Therapy of Multidrug Resistant Cancer","year":2016,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Staurosporine; Multiple drug resistance; Cancer; Nanotechnology; Nanoparticle; Liposome; Cancer therapy; Solid lipid nanoparticle; Pharmaceutical technology; Pharmacology; Chemistry; Cancer research; Medicine; Materials science; Kinase; Biochemistry; Chromatography; Internal medicine; Protein kinase C","score_opus":0.10518068074535437,"score_gpt":0.4701818753939174,"score_spread":0.36500119464856307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2233790834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8196491,0.0044925157,0.16933544,0.00050549215,0.00019466763,0.00031623343,0.00046753595,0.00088584743,0.0041531906],"genre_scores_gemma":[0.92469007,0.001912341,0.06553287,0.00015083728,0.0000359451,0.00016466719,0.00041237407,0.00012438542,0.006976532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984753,0.000015463145,0.000019800442,0.000031070806,0.0000682958,0.000017852572],"domain_scores_gemma":[0.9999298,0.000009075434,0.000022663058,0.000011256022,0.000017745773,0.000009419569],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023925054,0.00052924233,0.00027787779,0.00033124612,0.00021362852,0.00031536716,0.00035797324,0.00048245635,0.00064882665],"category_scores_gemma":[0.00014798938,0.0003229718,0.0003598718,0.0001950888,0.00025594517,0.00047268343,0.00034990165,0.00058877177,0.00041858415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010374521,0.000012168134,0.000024379766,0.000026603058,0.0000034348848,0.000014368282,0.00000740085,0.00004491564,0.99757737,0.00013217541,0.000040483817,0.0021062612],"study_design_scores_gemma":[0.000004737567,0.000033939577,0.00016037266,0.0000012716089,0.000007928161,0.000057609246,0.0000023595337,0.00071888126,0.99764544,0.000015467289,0.0013472353,0.000004777466],"about_ca_topic_score_codex":0.0008276382,"about_ca_topic_score_gemma":0.0014758558,"teacher_disagreement_score":0.0008276382,"about_ca_system_score_codex":0.00039836304,"about_ca_system_score_gemma":0.00041765187,"threshold_uncertainty_score":0.0028903484},"labels":[],"label_agreement":null},{"id":"W2289356514","doi":"10.1007/s11095-016-1892-6","title":"Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections","year":2016,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Australian Research Council; National Institutes of Health","keywords":"Aerosolization; Phage therapy; Freeze-drying; Spray drying; Mannitol; Chemistry; Chromatography; Materials science; Microbiology; Inhalation; Bacteriophage; Medicine; Biology; Organic chemistry","score_opus":0.28835810401785705,"score_gpt":0.5016757986436856,"score_spread":0.21331769462582856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2289356514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9715826,0.0030711954,0.023485595,0.00008005826,0.00006029299,0.00012459647,0.000156105,0.000085358304,0.0013540247],"genre_scores_gemma":[0.9635327,0.0026264768,0.030955225,0.0000641605,0.000025931393,0.000060397553,0.00033462772,0.00004220597,0.0023583202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998468,0.000023419305,0.000011511044,0.000023853441,0.00007011585,0.000024209952],"domain_scores_gemma":[0.99990344,0.000032386837,0.00002520366,0.0000099912395,0.000017445116,0.000011653593],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031413205,0.0002364039,0.0003214114,0.00019702471,0.000173288,0.00027125495,0.0002066576,0.00031162106,0.0005098563],"category_scores_gemma":[0.0002227776,0.00015548669,0.00046333883,0.00017718521,0.00013929004,0.00019197016,0.00021725817,0.0005120158,0.0001837611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021330407,0.000021891936,0.00008860233,0.000027617474,0.000002436335,0.00001857964,0.000013363066,0.000045893088,0.9971097,0.000019442814,0.00001723716,0.0026139796],"study_design_scores_gemma":[0.00000790182,0.00027022962,0.0014538879,0.0000053493677,0.000013948905,0.00013364738,0.000009664437,0.0003801208,0.99708086,0.000010351681,0.0006317774,0.0000023967377],"about_ca_topic_score_codex":0.00030882112,"about_ca_topic_score_gemma":0.00049660174,"teacher_disagreement_score":0.0005098563,"about_ca_system_score_codex":0.00012194332,"about_ca_system_score_gemma":0.00016654428,"threshold_uncertainty_score":0.0017056465},"labels":[],"label_agreement":null},{"id":"W2342213528","doi":"10.1007/s11095-016-1920-6","title":"Tissue Permeability Effects Associated with the Use of Mucoadhesive Cationic Nanoformulations of Docetaxel in the Bladder","year":2016,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development; University of British Columbia","funders":"Canadian Institutes of Health Research; Genome British Columbia","keywords":"Chemistry; Glutaraldehyde; Nuclear chemistry; Drug carrier; In vivo; Chromatography; Drug delivery; Biomedical engineering; Medicine; Organic chemistry","score_opus":0.1898191633510393,"score_gpt":0.4265425569116588,"score_spread":0.23672339356061953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2342213528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997232,0.0015599048,0.0007305721,0.00003284967,0.000019493658,0.000012131831,0.00002805992,0.000013008532,0.0003718802],"genre_scores_gemma":[0.99832433,0.00069110986,0.0004428875,0.000014725759,0.000005754862,0.000005356228,0.000021555155,0.0000052014893,0.0004889571],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981195,0.00006718412,0.000014995496,0.000028019816,0.000032824595,0.00004505894],"domain_scores_gemma":[0.9997949,0.000068729234,0.00005986181,0.000016077269,0.000030401132,0.000030081985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038443314,0.00019814188,0.00020092177,0.00014616275,0.00018854775,0.0003022821,0.00013451977,0.00020866134,0.00069253176],"category_scores_gemma":[0.00046022012,0.00012832717,0.00027530405,0.00017371931,0.00026897245,0.0004073818,0.00016405385,0.00032439627,0.00009783484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012794205,0.000095320866,0.00048959185,0.00011210226,0.0000145573695,0.00013194546,0.00007536676,0.0002474001,0.9916853,0.000077388075,0.000060873077,0.005730704],"study_design_scores_gemma":[0.000017390925,0.0023069463,0.002365107,0.0000069525395,0.000045713317,0.00024476452,0.000048230144,0.00052261516,0.99377704,0.000009532158,0.00064903824,0.0000066735847],"about_ca_topic_score_codex":0.0016273065,"about_ca_topic_score_gemma":0.0018113315,"teacher_disagreement_score":0.0016273065,"about_ca_system_score_codex":0.00030803896,"about_ca_system_score_gemma":0.00033191626,"threshold_uncertainty_score":0.0032356977},"labels":[],"label_agreement":null},{"id":"W245246413","doi":"10.1023/a:1024422625596","title":"The Effects of Pluronic® Block Copolymers and Cremophor® EL on Intestinal Lipoprotein Processing and the Potential Link with P-Glycoprotein in Caco-2 Cells","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Chylomicron; Excipient; Poloxamer; P-glycoprotein; Lipoprotein; Chemistry; Efflux; Pharmacology; Drug carrier; Drug delivery; Secretion; Drug; Biochemistry; Cholesterol; Very low-density lipoprotein; Copolymer; Biology","score_opus":0.025925946913609017,"score_gpt":0.34517322665452616,"score_spread":0.31924727974091716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W245246413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99698824,0.0012993296,0.00051224756,0.00006404719,0.000022010261,0.000013608814,0.00010011383,0.000016107566,0.0009844344],"genre_scores_gemma":[0.99602026,0.0008302435,0.00070219283,0.000054726665,0.000014864869,0.000017915721,0.00017824894,0.000012382997,0.0021691716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981815,0.000055953067,0.000015848742,0.000021299333,0.00002391567,0.00006481094],"domain_scores_gemma":[0.9997731,0.000121493955,0.000031739208,0.000020266109,0.000023289249,0.000030222516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031809264,0.00030528227,0.00019595232,0.00015001625,0.00013584565,0.00027858154,0.00015183934,0.00042558752,0.0011490192],"category_scores_gemma":[0.00033398106,0.00023802667,0.00036509353,0.00014321029,0.00028556804,0.00052386353,0.00013990195,0.0004483047,0.00030501955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002202791,0.000093131006,0.00011233456,0.000057124984,0.000008358284,0.00011903212,0.00004235822,0.00013174636,0.9954646,0.00011281585,0.000039445622,0.001616296],"study_design_scores_gemma":[0.00004553981,0.00062640663,0.0016426212,0.0000030428296,0.000014044725,0.00007063738,0.000025076572,0.0005825559,0.99640155,0.000025999969,0.00055786094,0.0000046746886],"about_ca_topic_score_codex":0.0015397063,"about_ca_topic_score_gemma":0.0012146253,"teacher_disagreement_score":0.0015397063,"about_ca_system_score_codex":0.00030781934,"about_ca_system_score_gemma":0.00026085187,"threshold_uncertainty_score":0.0038439035},"labels":[],"label_agreement":null},{"id":"W2463433553","doi":"10.1007/s11095-013-1044-1","title":"Trastuzumab Labeled to High Specific Activity with 111In by Conjugation to G4 PAMAM Dendrimers Derivatized with Multiple DTPA Chelators Exhibits Increased Cytotoxic Potency on HER2-Positive Breast Cancer Cells","year":2013,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Dendrimers and Hyperbranched Polymers","field":"Materials Science","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Trastuzumab; Conjugate; Cytotoxic T cell; Chemistry; Cytotoxicity; Internalization; Molecular biology; In vitro; Cancer research; Medicine; Breast cancer; Biochemistry; Cancer; Biology; Internal medicine; Cell","score_opus":0.03470559185667479,"score_gpt":0.3388024073138273,"score_spread":0.30409681545715256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2463433553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974679,0.00053062,0.0009201805,0.000036415477,0.000009026761,0.000008341179,0.000039919807,0.000043539083,0.0009440907],"genre_scores_gemma":[0.9972128,0.00023082439,0.00071161013,0.00001566749,0.0000050027047,0.000007024847,0.00010307188,0.000012159651,0.0017018022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998772,0.000023912522,0.0000084629055,0.000022380103,0.000024708057,0.00004332365],"domain_scores_gemma":[0.9999113,0.000030113331,0.000016706557,0.000014194853,0.000010668363,0.000016938264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020349874,0.00033385213,0.00032324568,0.00017511829,0.00014199398,0.00030738593,0.00017064321,0.00029092538,0.00069202116],"category_scores_gemma":[0.00015440445,0.00017564572,0.00013376906,0.00020820246,0.00023059663,0.000226375,0.00017673148,0.00029258794,0.00021172097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012535234,0.000011779442,0.00010370482,0.000012351354,0.0000023903287,0.00003584657,0.000011960104,0.00008655381,0.9989065,0.00005079005,0.000016383028,0.0006364078],"study_design_scores_gemma":[0.0000056144145,0.00009593523,0.0005969205,6.286727e-7,0.000004479592,0.000052934458,0.0000028607337,0.0002411632,0.9986739,0.0000047594644,0.00031976795,9.99272e-7],"about_ca_topic_score_codex":0.00082859496,"about_ca_topic_score_gemma":0.0009445853,"teacher_disagreement_score":0.00082859496,"about_ca_system_score_codex":0.0004294487,"about_ca_system_score_gemma":0.00018911058,"threshold_uncertainty_score":0.0031158924},"labels":[],"label_agreement":null},{"id":"W2465028908","doi":"10.1007/s11095-006-9908-2","title":"The in Vitro Plasma Distribution of a Novel Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, Is Influenced by Differences in Plasma Lipid Concentrations","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Diabetes, Cardiovascular Risks, and Lipoproteins","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Pfizer","keywords":"Chemistry; Lipoprotein; Cholesterylester transfer protein; High-density lipoprotein; Low-density lipoprotein; Chromatography; Cholesteryl ester; Triglyceride; Cholesterol; Biochemistry","score_opus":0.06808056006676817,"score_gpt":0.36557032699823117,"score_spread":0.297489766931463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2465028908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900497,0.0045860135,0.003161541,0.00028670006,0.00007723835,0.000018650015,0.00041330387,0.00007399615,0.0013328951],"genre_scores_gemma":[0.99458164,0.0018501683,0.001329269,0.00009505743,0.000046811732,0.000024392333,0.0008535357,0.00004306392,0.0011760581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969375,0.000106270985,0.000016345512,0.000049906444,0.00004486663,0.000088927474],"domain_scores_gemma":[0.99970216,0.00013595568,0.000041183863,0.000033763263,0.000025651538,0.00006121018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035602867,0.0003899182,0.000478747,0.00022797784,0.00018517683,0.000689556,0.00024594823,0.00038932837,0.0012575057],"category_scores_gemma":[0.00071794353,0.00034392075,0.00027805084,0.00023812926,0.00035807787,0.0004259613,0.00014697251,0.0010453445,0.00060185086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052064625,0.00010368684,0.000530889,0.00004063573,0.000040624724,0.00006840497,0.000031248324,0.00017319493,0.9897267,0.00013143383,0.00019484086,0.0037519222],"study_design_scores_gemma":[0.00026390425,0.0017522576,0.010354656,0.0000066917596,0.00008945794,0.00039271376,0.000039753053,0.004057653,0.98162407,0.00010051133,0.0013024119,0.000015998152],"about_ca_topic_score_codex":0.0021084694,"about_ca_topic_score_gemma":0.0013698492,"teacher_disagreement_score":0.0021084694,"about_ca_system_score_codex":0.00050019997,"about_ca_system_score_gemma":0.0004951089,"threshold_uncertainty_score":0.0042067766},"labels":[],"label_agreement":null},{"id":"W2470343765","doi":"10.1007/s11095-013-1258-2","title":"Comparison of In Vitro Deposition of Pharmaceutical Aerosols in an Idealized Child Throat with In Vivo Deposition in the Upper Respiratory Tract of Children","year":2014,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta; United States Pharmacopeia","keywords":"In vivo; Deposition (geology); Throat; Respiratory tract; Medicine; Inhaler; Pharmacology; Respiratory system; Asthma; Chemistry; Immunology; Internal medicine; Surgery; Biology","score_opus":0.13458168635043813,"score_gpt":0.4813313325311045,"score_spread":0.3467496461806664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2470343765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993163,0.00074373215,0.0048149736,0.000033248834,0.000023554345,0.00005406204,0.00014707842,0.0000139074855,0.0010064724],"genre_scores_gemma":[0.9927691,0.0007922237,0.005621759,0.000039329512,0.00001034261,0.000034603567,0.00019137945,0.000012260375,0.00052913424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927443,0.000250845,0.00006269875,0.000101455465,0.00018975792,0.0001208648],"domain_scores_gemma":[0.9989975,0.00047232356,0.00017140589,0.000128478,0.00014808119,0.00008235014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00095109147,0.00036460033,0.0003625491,0.0001969248,0.00027937256,0.00049911096,0.00032185632,0.0005143868,0.00066893245],"category_scores_gemma":[0.0010889393,0.0002835123,0.00040449036,0.00014888475,0.0005630053,0.00036235544,0.00034749435,0.00042555158,0.00014198897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006747238,0.00007363838,0.0016130455,0.000098844,0.000017508406,0.0000922392,0.00007072778,0.0014569149,0.99451053,0.000113146474,0.00002676438,0.0012519336],"study_design_scores_gemma":[0.00002880781,0.002301462,0.014589799,0.000009523573,0.000046966976,0.00024453082,0.0002133511,0.004430335,0.97738725,0.000051679835,0.0006791396,0.000017104923],"about_ca_topic_score_codex":0.002621992,"about_ca_topic_score_gemma":0.0022496574,"teacher_disagreement_score":0.002621992,"about_ca_system_score_codex":0.0004745839,"about_ca_system_score_gemma":0.0006609379,"threshold_uncertainty_score":0.005213499},"labels":[],"label_agreement":null},{"id":"W2489073301","doi":"10.1007/s11095-016-2003-4","title":"Optimization of Spray Drying Conditions for Yield, Particle Size and Biological Activity of Thermally Stable Viral Vectors","year":2016,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Active ingredient; Particle size; Yield (engineering); Volumetric flow rate; Response surface methodology; Materials science; Spray drying; Chemistry; Chromatography; Thermodynamics; Composite material; Biology; Physics; Bioinformatics","score_opus":0.26075480940799795,"score_gpt":0.47126059465350634,"score_spread":0.2105057852455084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2489073301","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.971132,0.0017061359,0.025471963,0.00006091333,0.00003850926,0.00016165776,0.00024090816,0.00014983815,0.0010381239],"genre_scores_gemma":[0.96519107,0.0016648098,0.031483267,0.000043073152,0.000014752752,0.000142166,0.00039210287,0.00015707075,0.0009117882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997031,0.00004971694,0.00004422051,0.00005945596,0.00009893459,0.0000445806],"domain_scores_gemma":[0.9996277,0.00015074146,0.00009004738,0.000025461162,0.000082858365,0.000023131637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077543274,0.0004879097,0.0003270563,0.00032139855,0.0002777276,0.0003967238,0.0002689999,0.0003319843,0.0008166089],"category_scores_gemma":[0.0009881172,0.00024558482,0.00037309428,0.0003141015,0.00024557966,0.00048307737,0.00019663267,0.0004762357,0.00024554407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005631397,0.000020423013,0.00011508984,0.000026668962,0.000005069519,0.000012889185,0.000021911404,0.00020003019,0.99803644,0.000044399825,0.000019232617,0.0014415256],"study_design_scores_gemma":[0.000006564912,0.00010773871,0.0007429751,0.0000032086068,0.000012300163,0.000032232714,0.000009885758,0.0008829423,0.99780303,0.000022821023,0.00037080774,0.0000055789646],"about_ca_topic_score_codex":0.0007319601,"about_ca_topic_score_gemma":0.0014867873,"teacher_disagreement_score":0.0008166089,"about_ca_system_score_codex":0.00035567945,"about_ca_system_score_gemma":0.00036618978,"threshold_uncertainty_score":0.004100919},"labels":[],"label_agreement":null},{"id":"W2500260770","doi":"10.1007/s11095-016-2002-5","title":"Tuning Ciprofloxacin Release Profiles from Liposomally Encapsulated Nanocrystalline Drug","year":2016,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Northern Lipids (Canada)","funders":"","keywords":"Drug; Nanocrystalline material; Pharmaceutical technology; Drug carrier; Drug delivery; Chemistry; Pharmacology; Nanoparticle; Nanotechnology; Medicine; Materials science; Chromatography","score_opus":0.3290463467627443,"score_gpt":0.5239574989848663,"score_spread":0.19491115222212202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2500260770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99377775,0.0009860515,0.0043379483,0.000055142456,0.000010039812,0.000055943612,0.00012309596,0.000057029705,0.00059712864],"genre_scores_gemma":[0.9929426,0.00073281233,0.0054268786,0.000020808915,0.0000045230045,0.000031185435,0.000104264895,0.000024753252,0.00071229634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982435,0.000023673556,0.000022166301,0.000049275503,0.00005107756,0.000029422345],"domain_scores_gemma":[0.99979407,0.00005891447,0.00007464282,0.000019955985,0.000034951972,0.000017504768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028176745,0.00025506478,0.00019193484,0.00016643776,0.00013485189,0.00031351479,0.00017541526,0.00030913338,0.00051339733],"category_scores_gemma":[0.00053526345,0.00012560491,0.00015285795,0.00010639548,0.00021952871,0.00029609003,0.00014680359,0.00034297188,0.00023764979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009408131,0.000016609092,0.00014102335,0.000029077346,0.0000026928062,0.000018410768,0.000011634515,0.00017266057,0.99784684,0.000020321146,0.000013114439,0.0016333789],"study_design_scores_gemma":[0.00001125467,0.000271086,0.00074052834,0.0000040162995,0.0000074814066,0.000039384577,0.000005125201,0.0009759376,0.9975877,0.0000043984064,0.0003490763,0.0000040503946],"about_ca_topic_score_codex":0.0010313081,"about_ca_topic_score_gemma":0.0015052195,"teacher_disagreement_score":0.0010313081,"about_ca_system_score_codex":0.00049133674,"about_ca_system_score_gemma":0.00030230862,"threshold_uncertainty_score":0.0035648942},"labels":[],"label_agreement":null},{"id":"W252847268","doi":"10.1023/a:1025706110520","title":"The Effect of Low Concentrations of Molecularly Dispersed Poly(Vinylpyrrolidone) on Indomethacin Crystallization from the Amorphous State","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Polymer crystallization and properties","field":"Materials Science","cited_by":123,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity Western University","funders":"Purdue University","keywords":"Crystallization; Amorphous solid; Nucleation; Particle size; Chemical engineering; Materials science; Crystal (programming language); Particle (ecology); Crystallography; Chemistry; Organic chemistry","score_opus":0.06736344411446592,"score_gpt":0.38471248651192785,"score_spread":0.3173490423974619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W252847268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970009,0.0011809904,0.0005579676,0.00007877701,0.000037682774,0.00002601174,0.00015954315,0.00003131379,0.0009267826],"genre_scores_gemma":[0.9967998,0.0005964354,0.0013815773,0.000029646919,0.000020429441,0.000017234153,0.00017990111,0.00002389161,0.00095102814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979347,0.000056576897,0.000028069311,0.00003556404,0.000036815432,0.000049471506],"domain_scores_gemma":[0.99910057,0.0005951441,0.00010070112,0.00006589772,0.00006443471,0.000073203664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024445646,0.0002686034,0.00034840425,0.00017134576,0.0002381025,0.00039057,0.00026899375,0.0003478996,0.001197927],"category_scores_gemma":[0.0008500086,0.00020955077,0.0002075179,0.00018316615,0.00045046734,0.00036780656,0.000149732,0.00069308275,0.0002353489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010212271,0.00010835884,0.0001221718,0.000051989948,0.0000063874704,0.000060368093,0.000030230412,0.00012263148,0.997493,0.00005399535,0.00003528662,0.0008943609],"study_design_scores_gemma":[0.000029480065,0.00027062764,0.0005818762,0.0000024559913,0.000005912595,0.000021218553,0.000009748845,0.00037894186,0.998478,0.000010066195,0.00020886234,0.0000027642172],"about_ca_topic_score_codex":0.0016762608,"about_ca_topic_score_gemma":0.0024424142,"teacher_disagreement_score":0.0016762608,"about_ca_system_score_codex":0.00038724882,"about_ca_system_score_gemma":0.0003915088,"threshold_uncertainty_score":0.0040075183},"labels":[],"label_agreement":null},{"id":"W2562574147","doi":"10.1007/s11095-016-2082-2","title":"Local Radiation Treatment of HER2-Positive Breast Cancer Using Trastuzumab-Modified Gold Nanoparticles Labeled with 177Lu","year":2016,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Terry Fox Foundation; Canadian Cancer Society","keywords":"Trastuzumab; Breast cancer; Colloidal gold; Medicine; Oncology; Cancer; Cancer research; Internal medicine; Nanoparticle; Pharmacology; Chemistry; Nanotechnology; Materials science","score_opus":0.10001117075615273,"score_gpt":0.438216325393721,"score_spread":0.3382051546375683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2562574147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935355,0.002280083,0.0021322123,0.000068712165,0.00003325065,0.000045759647,0.000034018038,0.00005820608,0.0018121883],"genre_scores_gemma":[0.9960871,0.0008680459,0.001108882,0.000040013474,0.000009337486,0.000024120272,0.000046910405,0.00002134396,0.001794152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998983,0.00003350795,0.0000046098066,0.000020634969,0.000014731053,0.000028049777],"domain_scores_gemma":[0.9999478,0.00002079066,0.000012312985,0.000008330048,0.0000038997828,0.000006907341],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029213526,0.00031910502,0.00041614228,0.00019002827,0.00018212125,0.00020490606,0.0003296561,0.00031363947,0.0010591894],"category_scores_gemma":[0.0001733508,0.00020421132,0.0003177374,0.00017863851,0.00027159005,0.00023079327,0.00018373394,0.00028387498,0.00017708945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008965597,0.00014138519,0.00021505769,0.00013200333,0.000026873586,0.00008330271,0.00011550456,0.0006342448,0.9936419,0.00016033376,0.00009427981,0.0038585109],"study_design_scores_gemma":[0.00009664806,0.0019487193,0.0013944983,0.000007109258,0.00006775009,0.00017688633,0.00003708064,0.0009530479,0.9940971,0.000021648633,0.0011928629,0.0000065438735],"about_ca_topic_score_codex":0.00135025,"about_ca_topic_score_gemma":0.0014342634,"teacher_disagreement_score":0.00135025,"about_ca_system_score_codex":0.00033424355,"about_ca_system_score_gemma":0.00025404664,"threshold_uncertainty_score":0.003543377},"labels":[],"label_agreement":null},{"id":"W2589512786","doi":"10.1007/s11095-017-2124-4","title":"Evaluation of the ROS Inhibiting Activity and Mitochondrial Targeting of Phenolic Compounds in Fibroblast Cells Model System and Enhancement of Efficiency by Natural Deep Eutectic Solvent (NADES) Formulation","year":2017,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Phytochemicals and Antioxidant Activities","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"","keywords":"Mitochondrion; Fibroblast; Antioxidant; Chemistry; Reactive oxygen species; In vitro; Biochemistry; Mitochondrial ROS; Cell culture; Cell biology; Biophysics; Confocal microscopy; Biology","score_opus":0.10575161608585953,"score_gpt":0.4255250690177655,"score_spread":0.31977345293190595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2589512786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99262506,0.0014846269,0.0040047993,0.000045672565,0.000026639962,0.00003389051,0.00027132934,0.000033757773,0.0014742364],"genre_scores_gemma":[0.98857695,0.0015550338,0.0056272,0.000026050433,0.0000075744592,0.000051477695,0.00023752252,0.000010958697,0.0039073923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999385,0.0000078381,0.000007374161,0.000016680393,0.000019501524,0.000010100645],"domain_scores_gemma":[0.9999503,0.000011555805,0.000013904257,0.0000048203565,0.00001377356,0.000005589973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013238048,0.00025241068,0.00014512907,0.00012762025,0.000087714114,0.00012526284,0.00011906774,0.00018531036,0.00075646857],"category_scores_gemma":[0.00007087631,0.00007462629,0.0002091988,0.00012859752,0.000080672224,0.00016561976,0.00008176082,0.0002193747,0.00010580826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008406825,0.000025728452,0.000057395046,0.000044280623,0.0000027828362,0.00002658524,0.000008937303,0.000059964612,0.9984163,0.000039963597,0.000014409222,0.0012196755],"study_design_scores_gemma":[0.000004693544,0.00020390384,0.0003777594,0.0000015871416,0.000009044903,0.000026112708,0.000006949772,0.00021430715,0.9986456,0.000008406098,0.00050013216,0.0000015469725],"about_ca_topic_score_codex":0.00043158847,"about_ca_topic_score_gemma":0.0007975929,"teacher_disagreement_score":0.00075646857,"about_ca_system_score_codex":0.000092176095,"about_ca_system_score_gemma":0.000107136446,"threshold_uncertainty_score":0.0025306344},"labels":[],"label_agreement":null},{"id":"W2605184048","doi":"10.1007/s11095-017-2150-2","title":"Therapeutic Drug Monitoring of Golimumab in the Treatment of Ulcerative Colitis","year":2017,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Golimumab; Medicine; Ulcerative colitis; Adalimumab; Pharmacokinetics; Infliximab; Vedolizumab; Drug; Pharmacology; Therapeutic drug monitoring; Inflammatory bowel disease; Internal medicine; Tumor necrosis factor alpha; Immunology; Disease","score_opus":0.3633285884710078,"score_gpt":0.5597646341909384,"score_spread":0.19643604571993056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605184048","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012243232,0.9990293,0.00013904976,0.00019015024,0.000094505645,0.000003596122,0.000013217874,0.000004711958,0.0004031497],"genre_scores_gemma":[0.0015611365,0.99713326,0.0003349903,0.00031171957,0.0002243909,0.000008090666,0.000038755134,0.0000016079479,0.00038601388],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99966884,0.000072491785,0.00004825201,0.00004507613,0.00013565316,0.000029756533],"domain_scores_gemma":[0.9994122,0.00030116548,0.00010682646,0.000013007538,0.00012522578,0.000041585714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009077382,0.0007815031,0.0018858165,0.0019431805,0.00020280143,0.0011182857,0.0009501722,0.0010836291,0.0020069154],"category_scores_gemma":[0.0011375156,0.00025216365,0.0007141879,0.0016768778,0.00048987695,0.00090409955,0.0006274108,0.0020708444,0.001048293],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018605843,0.00007063477,0.0002783219,0.009858124,0.00014425373,0.0002881238,0.000028707424,0.0003280031,0.0016097964,0.0022616906,0.014995153,0.96995103],"study_design_scores_gemma":[0.00012729761,0.00028971187,0.0019605164,0.0048030787,0.00048524176,0.002698473,0.000060278922,0.00035124374,0.0013959843,0.002730524,0.9850552,0.000042445427],"about_ca_topic_score_codex":0.0007989712,"about_ca_topic_score_gemma":0.0017451996,"teacher_disagreement_score":0.0020069154,"about_ca_system_score_codex":0.0005586421,"about_ca_system_score_gemma":0.00088371633,"threshold_uncertainty_score":0.0067138076},"labels":[],"label_agreement":null},{"id":"W2605316130","doi":"10.1007/s11095-017-2156-9","title":"Insights and Lessons from a Scientific Conference on Non-Invasive Delivery of Macromolecules","year":2017,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Pipeline (software); Medicine; Pharmacology; Macromolecule; Engineering ethics; Chemistry; Computer science; Engineering; Biochemistry","score_opus":0.5042868738303539,"score_gpt":0.5638847421154908,"score_spread":0.05959786828513691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2605316130","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0062965928,0.111892484,0.006183651,0.8190078,0.035112698,0.00003376429,0.00008180108,0.00007709944,0.021314098],"genre_scores_gemma":[0.2628737,0.15958709,0.012604381,0.43943936,0.067791514,0.0002458046,0.00019032294,0.00042523263,0.05684262],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9845285,0.0055516837,0.00086824637,0.0015224834,0.0051733297,0.002355751],"domain_scores_gemma":[0.9557856,0.023663012,0.0016990872,0.0018536611,0.009884679,0.0071141114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.049861748,0.001380481,0.0015243001,0.0018557301,0.006069854,0.020632567,0.002442864,0.018849446,0.0077597178],"category_scores_gemma":[0.030871859,0.00049097085,0.0011705267,0.0015434192,0.013667143,0.015432534,0.011072719,0.030161344,0.002367751],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086113554,0.0006217656,0.0009537972,0.0020282285,0.00017223983,0.0013129329,0.007819159,0.0015106491,0.0076601594,0.4170925,0.32098177,0.23898555],"study_design_scores_gemma":[0.000074733696,0.0002852252,0.0007348737,0.0011391524,0.00004396431,0.0003116905,0.004103764,0.00037929422,0.003478285,0.13056603,0.8587397,0.00014326084],"about_ca_topic_score_codex":0.0021261487,"about_ca_topic_score_gemma":0.0031002862,"teacher_disagreement_score":0.049861748,"about_ca_system_score_codex":0.008131282,"about_ca_system_score_gemma":0.011728943,"threshold_uncertainty_score":0.26369727},"labels":[],"label_agreement":null},{"id":"W2611914917","doi":"10.1007/s11095-017-2172-9","title":"Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro","year":2017,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Trinity College Dublin; Ministry of Higher Education and Scientific Research; Flight Attendant Medical Research Institute","keywords":"Abcg2; Cell culture; Biology; Cell biology; Efflux; Epithelium; In vitro; Chemistry; Molecular biology; Pharmacology; ATP-binding cassette transporter; Transporter; Biochemistry","score_opus":0.08652626276649489,"score_gpt":0.45647679813645065,"score_spread":0.36995053536995576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2611914917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98355454,0.0063751163,0.002765631,0.00033967252,0.000049996357,0.000043677395,0.0015461334,0.000078099125,0.0052472167],"genre_scores_gemma":[0.98396814,0.0024236413,0.0021463109,0.00012743889,0.00002530579,0.000050486262,0.0042103035,0.00002185185,0.007026568],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994905,0.0001732859,0.000045473746,0.00007120129,0.00012220717,0.0000971865],"domain_scores_gemma":[0.99978334,0.000084631,0.000014228815,0.000039678613,0.00005193944,0.000026227563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003643498,0.00023559295,0.0002976067,0.00029126063,0.0003696955,0.00053994235,0.00017379502,0.00031946175,0.0019414093],"category_scores_gemma":[0.0002817207,0.00021110414,0.0003291006,0.00049376144,0.0002525992,0.000307308,0.00025311607,0.00062285824,0.00094137026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027052202,0.00008840793,0.00077770825,0.00009855199,0.000016044514,0.00013806508,0.000106015475,0.00014460199,0.99618655,0.00020424613,0.00023267986,0.0017365888],"study_design_scores_gemma":[0.000037317317,0.00049536146,0.013355259,0.000012136102,0.00005587917,0.00068658363,0.00022075616,0.0020948965,0.9765831,0.00009082428,0.006357535,0.000010254974],"about_ca_topic_score_codex":0.0042866403,"about_ca_topic_score_gemma":0.0024780617,"teacher_disagreement_score":0.0042866403,"about_ca_system_score_codex":0.0003127917,"about_ca_system_score_gemma":0.00031208518,"threshold_uncertainty_score":0.008523405},"labels":[],"label_agreement":null},{"id":"W2670200616","doi":"10.1007/s11095-017-2213-4","title":"Anti-Tuberculosis Bacteriophage D29 Delivery with a Vibrating Mesh Nebulizer, Jet Nebulizer, and Soft Mist Inhaler","year":2017,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Australian Research Council","keywords":"Nebulizer; Aerosolization; Chemistry; Inhaler; Mist; Inhalation; Anesthesia; Medicine; Immunology; Asthma","score_opus":0.1324092578339176,"score_gpt":0.4373024666922579,"score_spread":0.3048932088583403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2670200616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911936,0.0011219023,0.0066699563,0.00010661329,0.000052075546,0.00006044171,0.00005239816,0.00006802777,0.0006750954],"genre_scores_gemma":[0.98731494,0.00073949806,0.009819545,0.000092001,0.000022981503,0.00003641347,0.000052000647,0.000015846903,0.0019068078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987113,0.000013141846,0.000011352362,0.000031103616,0.000048553266,0.000024795838],"domain_scores_gemma":[0.99993575,0.00001470335,0.000015377254,0.0000056858366,0.000007619796,0.000020880501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019298063,0.00017264808,0.00027054493,0.0001719438,0.00017331362,0.00022470391,0.00018504322,0.00045648453,0.00044581702],"category_scores_gemma":[0.00013078813,0.00011456343,0.00026583613,0.00008902301,0.00019371288,0.00019570118,0.00021740342,0.00030819818,0.00011853836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000085885265,0.000027217588,0.000065510205,0.000015596706,0.0000028020238,0.0000159299,0.0000053921895,0.000077725665,0.9973686,0.000032021562,0.000015871852,0.0022874458],"study_design_scores_gemma":[0.000041508392,0.0008015796,0.0017379117,0.0000033291708,0.0000167481,0.00008661882,0.0000108786635,0.0021129586,0.9943797,0.00002242381,0.00078011083,0.0000062368044],"about_ca_topic_score_codex":0.0008369715,"about_ca_topic_score_gemma":0.0011218382,"teacher_disagreement_score":0.0008369715,"about_ca_system_score_codex":0.00021600668,"about_ca_system_score_gemma":0.00033286438,"threshold_uncertainty_score":0.0016642213},"labels":[],"label_agreement":null},{"id":"W2701578380","doi":"10.1007/s11095-017-2197-0","title":"Design and Evaluation of RGD-Modified Gemini Surfactant-Based Lipoplexes for Targeted Gene Therapy in Melanoma Model","year":2017,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Pulmonary surfactant; Melanoma; Genetic enhancement; Pharmaceutical technology; Pharmacology; Chemistry; Cancer research; Medicine; Computational biology; Gene; Biology; Chromatography; Biochemistry","score_opus":0.4145853485191153,"score_gpt":0.5158499509962368,"score_spread":0.10126460247712143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2701578380","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98678106,0.0016772371,0.01059393,0.000071597235,0.000018256815,0.00015668398,0.00012219376,0.000047339534,0.0005317117],"genre_scores_gemma":[0.98111355,0.0016821873,0.015057238,0.000051414776,0.000006707276,0.0001301853,0.0002471435,0.000019111973,0.0016925102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999032,0.000017887993,0.000012842357,0.000022083796,0.000027665703,0.000016281116],"domain_scores_gemma":[0.9999175,0.000010091836,0.000027599162,0.000006008923,0.000021995327,0.000016726717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033688857,0.00027176828,0.00018714034,0.00018634016,0.00013436926,0.00021778268,0.00017861737,0.00032445783,0.00032851598],"category_scores_gemma":[0.00019475853,0.00012677028,0.00022626475,0.00014400807,0.00013617157,0.0002604627,0.00013778424,0.000264773,0.00012861015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007245943,0.000025902002,0.00006930969,0.000038072536,0.0000045900797,0.000022131251,0.000010616473,0.00022458223,0.9981187,0.00009656205,0.000013786723,0.0013031546],"study_design_scores_gemma":[0.000017393793,0.0002793084,0.00026595578,0.000002427143,0.000012408409,0.00003954864,0.0000050699937,0.0010401172,0.99751806,0.000014037404,0.0008030178,0.0000027809401],"about_ca_topic_score_codex":0.00044800653,"about_ca_topic_score_gemma":0.0006710568,"teacher_disagreement_score":0.00044800653,"about_ca_system_score_codex":0.0003525853,"about_ca_system_score_gemma":0.0002857889,"threshold_uncertainty_score":0.0025582314},"labels":[],"label_agreement":null},{"id":"W2754755063","doi":"10.1007/s11095-017-2259-3","title":"Pharmacokinetic Considerations for Antibody-Drug Conjugates against Cancer","year":2017,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Pharmacokinetics; Antibody-drug conjugate; Drug; Cancer; Distribution (mathematics); Payload (computing); Medicine; Pharmacology; Monoclonal antibody; Cancer research; Antibody; Chemistry; Internal medicine; Immunology; Computer science","score_opus":0.8113589362850359,"score_gpt":0.7279344229882478,"score_spread":0.08342451329678802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754755063","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021756414,0.9981173,0.0003617988,0.0002441336,0.00017760608,0.000007455399,0.000017763225,0.000008198757,0.0008480768],"genre_scores_gemma":[0.0020247581,0.99567527,0.0004844046,0.00035637236,0.0002155537,0.000014291218,0.000039354687,0.0000033809376,0.0011866584],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99969137,0.00007341851,0.000037203918,0.00004535489,0.000120074874,0.000032627395],"domain_scores_gemma":[0.9996118,0.00022677566,0.000062738574,0.000010072637,0.00006929623,0.000019371924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009984324,0.0010176746,0.0016819896,0.0014229998,0.00020717017,0.0011880758,0.0008881011,0.0014780205,0.0037209839],"category_scores_gemma":[0.0012427694,0.0003806527,0.0007767107,0.0012557906,0.0004522223,0.0013863788,0.0006412477,0.0024342777,0.0018472553],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024777677,0.00013459448,0.00012593607,0.016367981,0.00017462828,0.00039579667,0.000049216065,0.0010504881,0.0062881047,0.005816206,0.028982338,0.9403669],"study_design_scores_gemma":[0.00009941661,0.0002829532,0.0004687256,0.002439172,0.00026201882,0.0017951406,0.000034511017,0.00047058682,0.0029853,0.0028856907,0.988247,0.00002949551],"about_ca_topic_score_codex":0.00068102113,"about_ca_topic_score_gemma":0.0011865998,"teacher_disagreement_score":0.0037209839,"about_ca_system_score_codex":0.00064373034,"about_ca_system_score_gemma":0.00076802354,"threshold_uncertainty_score":0.012447894},"labels":[],"label_agreement":null},{"id":"W2769001179","doi":"10.1007/s11095-017-2304-2","title":"Inhalation Biopharmaceutics: Progress Towards Comprehending the Fate of Inhaled Medicines","year":2017,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Biopharmaceutics; Inhalation; Pharmacology; Medicine; Intensive care medicine; Pharmaceutical technology; Anesthesia; Chemistry; Pharmacognosy","score_opus":0.34910389529868036,"score_gpt":0.5551901220412752,"score_spread":0.2060862267425948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769001179","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04976297,0.50686437,0.41442192,0.0098497495,0.0008944459,0.0001810728,0.0004597671,0.0004955699,0.017070198],"genre_scores_gemma":[0.31325728,0.5414878,0.12686898,0.004586352,0.0027769709,0.00018741489,0.0006480144,0.0002594334,0.009927792],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99893206,0.0002664903,0.00007150532,0.0001930408,0.00047416484,0.00006270298],"domain_scores_gemma":[0.9979481,0.0011814391,0.00025939854,0.00025644177,0.00029547611,0.000059111964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029020386,0.001156344,0.0018145874,0.0012531709,0.00046107438,0.0036494583,0.0013090058,0.0025424177,0.0019412697],"category_scores_gemma":[0.0027409017,0.0004412153,0.0008621497,0.0006307151,0.002107949,0.0048621497,0.0015837445,0.003732087,0.0011070706],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032990245,0.0003795185,0.0044530425,0.007616561,0.00015417674,0.0004998634,0.0009160148,0.00947518,0.3541569,0.091595635,0.0042699208,0.5261533],"study_design_scores_gemma":[0.000056454453,0.0011061693,0.005477544,0.0017688753,0.00026242985,0.0025846798,0.0012328735,0.052004967,0.44462997,0.20991011,0.28073794,0.000227963],"about_ca_topic_score_codex":0.0011757151,"about_ca_topic_score_gemma":0.00081390893,"teacher_disagreement_score":0.0036494583,"about_ca_system_score_codex":0.00089466595,"about_ca_system_score_gemma":0.002031364,"threshold_uncertainty_score":0.01534766},"labels":[],"label_agreement":null},{"id":"W2777223225","doi":"10.1007/s11095-017-2329-6","title":"Drug discovery, development and delivery in Alzheimer’s disease","year":2017,"lang":"en","type":"editorial","venue":"Pharmaceutical Research","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Alzheimer's disease; Disease; Drug discovery; Medicine; Drug delivery; Drug development; Drug; Intensive care medicine; Pharmacology; Biology; Bioinformatics; Chemistry; Internal medicine","score_opus":0.22664196561031696,"score_gpt":0.5087041294806063,"score_spread":0.2820621638702893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2777223225","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00002462011,0.01810903,0.00037024004,0.052661337,0.9274917,0.00001616233,0.000033278335,0.000056982466,0.0012366129],"genre_scores_gemma":[0.00037722386,0.010268101,0.0002408076,0.019543126,0.9637345,0.000023055141,0.000019513443,0.00003612412,0.005757567],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98902774,0.002404802,0.0014187926,0.0008750077,0.0056735286,0.00060009613],"domain_scores_gemma":[0.95688236,0.025281886,0.002217437,0.001043039,0.010237925,0.0043373816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.015369424,0.00478277,0.004917564,0.0052595995,0.0038576499,0.010102997,0.0048601152,0.029132646,0.008615381],"category_scores_gemma":[0.03860146,0.0017706167,0.0032186862,0.00213324,0.005971982,0.00637734,0.0035906343,0.034764376,0.0077560497],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030690666,0.0000124149765,0.000012903256,0.00025605367,0.00002720199,0.00006901957,0.000009886667,0.000051037507,0.000036159377,0.0010884565,0.9891371,0.009268995],"study_design_scores_gemma":[0.00009566056,0.000037063,0.0001314223,0.000746655,0.000082383354,0.00027096266,0.00002306411,0.00043258455,0.00013825778,0.0052883807,0.9927254,0.00002812123],"about_ca_topic_score_codex":0.0025313895,"about_ca_topic_score_gemma":0.006958449,"teacher_disagreement_score":0.029132646,"about_ca_system_score_codex":0.005618944,"about_ca_system_score_gemma":0.0062483903,"threshold_uncertainty_score":0.08128226},"labels":[],"label_agreement":null},{"id":"W285103999","doi":"10.1023/a:1011054930439","title":"Novel Polymeric Micelles Based on the Amphiphilic Diblock Copolymer Poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide)","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Polymer Synthesis and Characterization","field":"Chemistry","cited_by":150,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Copolymer; Amphiphile; Micelle; Lactide; Polymer chemistry; Materials science; 2-Pyrrolidone; Polymer; Chemistry; Organic chemistry; Aqueous solution","score_opus":0.1360056784848311,"score_gpt":0.4012752002206972,"score_spread":0.26526952173586604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W285103999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9172553,0.01239583,0.058539435,0.0008690963,0.00056627893,0.000404617,0.00040505326,0.0011382529,0.008426137],"genre_scores_gemma":[0.9544694,0.0038591854,0.029700752,0.00044804174,0.000108760396,0.00017041691,0.0003524313,0.00008969179,0.010801386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989116,0.0000142160525,0.000009839306,0.000024302728,0.00003148995,0.00002895277],"domain_scores_gemma":[0.9998287,0.000029523546,0.00004792396,0.000007620797,0.000037506587,0.000048673686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026215732,0.0005050532,0.00024108932,0.00021906389,0.00015876075,0.0004006634,0.0003413917,0.0005130679,0.0010325772],"category_scores_gemma":[0.00024655633,0.00023888152,0.00017958532,0.00009533716,0.00021918003,0.00065021793,0.00025875506,0.0004839512,0.0006899416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000077496334,0.000031729178,0.00003352279,0.000061431114,0.0000056079934,0.000045290893,0.000011551166,0.000058390513,0.9968509,0.00036868532,0.00008572713,0.0023696392],"study_design_scores_gemma":[0.00009015478,0.00025858774,0.0003700778,0.000008538496,0.00002250506,0.00022035315,0.0000051487414,0.0012454235,0.99178326,0.000084517575,0.005904713,0.0000067774645],"about_ca_topic_score_codex":0.0001906573,"about_ca_topic_score_gemma":0.0005236027,"teacher_disagreement_score":0.0010325772,"about_ca_system_score_codex":0.00030658895,"about_ca_system_score_gemma":0.00022141237,"threshold_uncertainty_score":0.0034543872},"labels":[],"label_agreement":null},{"id":"W2887133962","doi":"10.1007/s11095-018-2481-7","title":"Doing it All - How Families are Reshaping Rare Disease Research","year":2018,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Research Opportunities Initiative, University of North Carolina; Fondation des Fondateurs; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Pitt Hopkins Research Foundation; University of North Carolina; Rare Disease Foundation; Charcot-Marie-Tooth Association","keywords":"Odds; Disease; Liberian dollar; Rare disease; Face (sociological concept); Space (punctuation); Medicine; Courage; Psychology; Public relations; Political science; Sociology; Business; Law; Social science; Pathology","score_opus":0.27800078228604286,"score_gpt":0.5093746504667279,"score_spread":0.23137386818068506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887133962","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":"incentives","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":"incentives","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036226413,0.036802836,0.015463036,0.8996612,0.021228736,0.00006756526,0.00015543858,0.00072107225,0.022277573],"genre_scores_gemma":[0.14874059,0.06510818,0.052779008,0.6672828,0.03205472,0.00043057007,0.0003692476,0.0010325018,0.03220233],"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9678014,0.0188761,0.0016043609,0.0027753552,0.0063312985,0.0026114578],"domain_scores_gemma":[0.8681352,0.06319723,0.0058127907,0.019082997,0.016365236,0.027406532],"candidate_categories":["metaresearch","sts"],"consensus_categories":[],"category_scores_codex":[0.055424877,0.0012549799,0.0018621933,0.004185359,0.008050072,0.012174384,0.0031719333,0.014072946,0.018710272],"category_scores_gemma":[0.102812305,0.0009317873,0.0019393103,0.0019208796,0.02459711,0.027274119,0.013882031,0.023979694,0.006780876],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022736448,0.00038692474,0.005155699,0.0010416938,0.00041623763,0.0017132412,0.007664419,0.00069475995,0.0023255826,0.20138985,0.4084574,0.37052682],"study_design_scores_gemma":[0.000102187994,0.00015069533,0.0014014456,0.0013541803,0.00017013158,0.0014299469,0.0047986815,0.00021307233,0.0009692045,0.34422627,0.64507776,0.000106474254],"about_ca_topic_score_codex":0.005214805,"about_ca_topic_score_gemma":0.0062939655,"teacher_disagreement_score":0.9919499,"about_ca_system_score_codex":0.004580056,"about_ca_system_score_gemma":0.02137963,"threshold_uncertainty_score":0.2931183},"labels":[],"label_agreement":null},{"id":"W2888873669","doi":"10.1007/s11095-018-2469-3","title":"Orcinol Glucoside Loaded Polymer - Lipid Hybrid Nanostructured Lipid Carriers: Potential Cytotoxic Agents against Gastric, Colon and Hepatoma Carcinoma Cell Lines","year":2018,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Science and Engineering Research Board; University Grants Commission","keywords":"Zeta potential; Polyethylene glycol; Differential scanning calorimetry; Chemistry; PEG ratio; In vivo; Cytotoxicity; Stearate; Crystallinity; Biophysics; In vitro; Nuclear chemistry; Materials science; Biochemistry; Nanoparticle; Nanotechnology; Organic chemistry; Biology","score_opus":0.15245105611372273,"score_gpt":0.46178571966462983,"score_spread":0.3093346635509071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888873669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99419034,0.0013125013,0.002493707,0.00007372765,0.000024554247,0.000025271765,0.00008478494,0.00005404648,0.0017411521],"genre_scores_gemma":[0.9944238,0.000932857,0.0018115776,0.00003476496,0.000005840746,0.000018209414,0.00008562948,0.000009686657,0.002677724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999959,0.0000068944,0.000002712641,0.000010188953,0.000010051413,0.000011138502],"domain_scores_gemma":[0.9999633,0.0000076203914,0.000009861255,0.0000028134798,0.000009138837,0.00000716612],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007437288,0.00021971109,0.00014798007,0.0001224962,0.00008545636,0.00018971832,0.000119436634,0.0002727765,0.0008405861],"category_scores_gemma":[0.00009445594,0.000087849796,0.00012309256,0.00012496232,0.00010983477,0.0002627258,0.00014211507,0.00022530094,0.0001773598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010348122,0.000016691405,0.000062768784,0.000035849433,0.0000027248357,0.000046645975,0.000012679963,0.000103924685,0.9972928,0.00008568126,0.00003115125,0.0022055656],"study_design_scores_gemma":[0.0000125461,0.00036985383,0.0006514846,0.000004164957,0.000019338791,0.00008832248,0.000015196296,0.0006844143,0.9964309,0.000018190498,0.0017011452,0.000004359691],"about_ca_topic_score_codex":0.00052759156,"about_ca_topic_score_gemma":0.0009103466,"teacher_disagreement_score":0.0008405861,"about_ca_system_score_codex":0.00015819467,"about_ca_system_score_gemma":0.00015119641,"threshold_uncertainty_score":0.002812028},"labels":[],"label_agreement":null},{"id":"W2899793262","doi":"10.1007/s11095-018-2533-z","title":"Establishment of a Mucin Secreting Cell Line Cx-03 from an Uterine Carcino Sarcoma","year":2018,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Bundesministerium für Bildung und Forschung","keywords":"Mucin; Sarcoma; Cell culture; Cancer research; Chemistry; Medicine; Biology; Pathology; Genetics","score_opus":0.25563821268145515,"score_gpt":0.4919345428789177,"score_spread":0.23629633019746255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899793262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9859416,0.0006410662,0.0070220325,0.0002222351,0.000077803605,0.00023386859,0.0012884405,0.0001179853,0.004454936],"genre_scores_gemma":[0.97617334,0.00081336166,0.011914712,0.00012429689,0.000024582296,0.00021217745,0.0027535858,0.00003811617,0.007945854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997042,0.000041053365,0.000057528305,0.000050810304,0.00008681579,0.00005955159],"domain_scores_gemma":[0.99962795,0.000115048875,0.000028542308,0.00010307516,0.00006205847,0.00006328193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044693548,0.00026157685,0.00038184065,0.00043014155,0.00041880406,0.00038115107,0.00042509692,0.00035699276,0.0019003113],"category_scores_gemma":[0.0002734569,0.00019385573,0.0005129055,0.00043998298,0.00022140457,0.00037071054,0.00040021676,0.0010187072,0.0012110497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008671715,0.00009438065,0.00053117785,0.000028720035,0.000005698084,0.0003307455,0.00012440473,0.000044855416,0.9972361,0.00037768716,0.00008562681,0.0010539702],"study_design_scores_gemma":[0.00004654713,0.0006714869,0.008015211,0.000009865286,0.0000476401,0.0014406447,0.00020378975,0.0018556976,0.9806284,0.000094633484,0.0069764657,0.000009547959],"about_ca_topic_score_codex":0.0028764587,"about_ca_topic_score_gemma":0.0029057981,"teacher_disagreement_score":0.0028764587,"about_ca_system_score_codex":0.00021266358,"about_ca_system_score_gemma":0.00035121187,"threshold_uncertainty_score":0.006357193},"labels":[],"label_agreement":null},{"id":"W2912631730","doi":"10.1007/s11095-019-2572-0","title":"Particle Surface Roughness Improves Colloidal Stability of Pressurized Pharmaceutical Suspensions","year":2019,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Alberta Innovates; Alberta Innovates - Technology Futures","keywords":"Dispersity; Colloid; Suspension (topology); Particle size; Surface roughness; Materials science; Particle (ecology); Chemical engineering; Rugosity; Chromatography; Chemistry; Composite material; Polymer chemistry","score_opus":0.1998341944877619,"score_gpt":0.4757712569549284,"score_spread":0.2759370624671665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912631730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965605,0.0008570577,0.0015157332,0.000061019444,0.000057428126,0.000013334109,0.000055859386,0.000050387087,0.0008287793],"genre_scores_gemma":[0.99651587,0.0003920576,0.0012510299,0.000049954884,0.00002078097,0.0000065710037,0.00008006922,0.000022600441,0.001661147],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977905,0.00002532518,0.000018963885,0.00003559749,0.00010068835,0.00004041306],"domain_scores_gemma":[0.9997714,0.000077845114,0.000051587245,0.000026107515,0.000049054965,0.000023924085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021717677,0.00021122173,0.00023562394,0.00019423685,0.00015324687,0.000441846,0.00016402069,0.0003977155,0.0015487425],"category_scores_gemma":[0.00048444603,0.00019018396,0.00030134406,0.00013037636,0.00013488327,0.00028100662,0.00022380972,0.00058777654,0.00032018742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089579786,0.000015897867,0.00012843686,0.00002048251,0.0000069544567,0.000022658953,0.000010594949,0.00012864439,0.9980254,0.00002267307,0.000032889788,0.0014958569],"study_design_scores_gemma":[0.000008887251,0.00020960749,0.002806537,0.0000020206237,0.000019178495,0.00004107974,0.000014364893,0.0015069376,0.9948655,0.000012045742,0.0005078274,0.000005983434],"about_ca_topic_score_codex":0.0007535837,"about_ca_topic_score_gemma":0.0010531222,"teacher_disagreement_score":0.0015487425,"about_ca_system_score_codex":0.0001570388,"about_ca_system_score_gemma":0.0001329202,"threshold_uncertainty_score":0.0051810145},"labels":[],"label_agreement":null},{"id":"W2943029043","doi":"10.1007/s11095-019-2605-8","title":"Systemic Exposure of Rituximab Increased by Ibrutinib: Pharmacokinetic Results and Modeling Based on the HELIOS Trial","year":2019,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Juravinski Cancer Centre; McMaster University","funders":"Janssen Research and Development; Pharmacyclics; F. Hoffmann-La Roche; AstraZeneca; Celgene; Gilead Sciences; H. Lundbeck A/S","keywords":"Rituximab; Bendamustine; Ibrutinib; Medicine; Pharmacokinetics; Population; Chronic lymphocytic leukemia; Placebo; Internal medicine; Cmin; Pharmacology; Ofatumumab; Oncology; Lymphoma; Leukemia; Cmax; Pathology","score_opus":0.16063657872043013,"score_gpt":0.4526326879843871,"score_spread":0.29199610926395697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943029043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9852115,0.0010807137,0.008472621,0.00026754677,0.000015492004,0.00004255723,0.0007461338,0.00012917917,0.0040343227],"genre_scores_gemma":[0.99678135,0.00032001475,0.0011255863,0.00011204568,0.000011437566,0.000040987008,0.0004363182,0.000037543883,0.0011346465],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99976474,0.00012617471,0.0000075737385,0.000044116954,0.00002444278,0.0000328853],"domain_scores_gemma":[0.9994165,0.00038599063,0.00010679544,0.00003429634,0.00002545129,0.00003104962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008944716,0.00055481616,0.0009999693,0.00019057916,0.00012363378,0.00091854186,0.00052560866,0.0005714173,0.0015737982],"category_scores_gemma":[0.0013445511,0.0002731958,0.0010380192,0.00030283307,0.00026122693,0.00043701663,0.00026157685,0.0007503869,0.00032941264],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01369608,0.0007199746,0.017991263,0.0003082848,0.0009862753,0.0010170997,0.00017630152,0.9103763,0.021386625,0.0027842156,0.0038322273,0.026725413],"study_design_scores_gemma":[0.0023752758,0.003766621,0.010762027,0.000028013781,0.00096749177,0.00062921044,0.00007736816,0.9632096,0.012187947,0.0025246802,0.0034033777,0.00006837542],"about_ca_topic_score_codex":0.0029668063,"about_ca_topic_score_gemma":0.0012999944,"teacher_disagreement_score":0.0029668063,"about_ca_system_score_codex":0.0004887016,"about_ca_system_score_gemma":0.00064629014,"threshold_uncertainty_score":0.0058991313},"labels":[],"label_agreement":null},{"id":"W2943104101","doi":"10.1007/s11095-019-2628-1","title":"Pharmacokinetic and Pharmacodynamic Properties of a Micro-Dose Nasal Spray Formulation of Desmopressin (AV002) in Healthy Water-Loaded Subjects","year":2019,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Lunds Universitet","keywords":"Pharmacokinetics; Bioavailability; Cmax; Pharmacodynamics; Desmopressin; Pharmacology; Nocturia; Nasal spray; Medicine; Antidiuretic; Urine; Area under the curve; Nasal administration; Chemistry; Internal medicine; Urinary system; Vasopressin","score_opus":0.15654773064503436,"score_gpt":0.4586445629769456,"score_spread":0.30209683233191126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943104101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986343,0.00036060603,0.0004935121,0.000021096925,0.000008480338,0.00011413996,0.00012057871,0.00002182931,0.00022560048],"genre_scores_gemma":[0.9976992,0.00024682502,0.0010707317,0.000048359117,0.000019650994,0.00011839,0.00020054528,0.0000071667155,0.0005891327],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998704,0.000051666015,0.0000067612254,0.000027553579,0.000029782408,0.000013741104],"domain_scores_gemma":[0.99984777,0.000041214615,0.000046692126,0.00001127064,0.000017454879,0.000035628163],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029434892,0.00028133957,0.00029498863,0.00008519721,0.00012194402,0.00018157333,0.0001415638,0.00026384112,0.0014437346],"category_scores_gemma":[0.0004901635,0.00014123037,0.0001578665,0.000082610044,0.00020522496,0.0001932386,0.00008949652,0.00031988113,0.00027262102],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06339977,0.007031547,0.011137285,0.0003741574,0.00014587076,0.00022161896,0.0002445481,0.000597999,0.853524,0.000063601015,0.00060064474,0.0626589],"study_design_scores_gemma":[0.01094365,0.5096502,0.22470573,0.000027751164,0.00034344292,0.0019496485,0.00028728961,0.005826529,0.24122883,0.0000882042,0.0049008247,0.00004792726],"about_ca_topic_score_codex":0.00048368095,"about_ca_topic_score_gemma":0.00050489727,"teacher_disagreement_score":0.0014437346,"about_ca_system_score_codex":0.00015582626,"about_ca_system_score_gemma":0.00017616872,"threshold_uncertainty_score":0.004829824},"labels":[],"label_agreement":null},{"id":"W2944996034","doi":"10.1007/s11095-019-2630-7","title":"Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics","year":2019,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Engineering and Physical Sciences Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Pharmaceutics; Kinetics; Spray drying; Pharmaceutical technology; Evaporation; Solvent; Chemistry; Chromatography; Chemical engineering; Materials science; Organic chemistry; Pharmacology; Thermodynamics; Medicine; Engineering","score_opus":0.28779820801919265,"score_gpt":0.4515362923744316,"score_spread":0.16373808435523896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944996034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.75192165,0.002522664,0.24223319,0.00015318584,0.000068005575,0.00015737317,0.000282846,0.0005296595,0.002131376],"genre_scores_gemma":[0.96129286,0.0013745747,0.035579875,0.000034603858,0.000015421647,0.000059257756,0.00013371669,0.000069812515,0.0014398565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997267,0.000033619825,0.000014129677,0.00005799519,0.00015116438,0.00001639387],"domain_scores_gemma":[0.9996538,0.00018069998,0.000052345116,0.000029771925,0.000072433824,0.000010998859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047771633,0.00043777883,0.00044262252,0.0002167688,0.00021993073,0.00046810802,0.00047843112,0.0006478816,0.0003760325],"category_scores_gemma":[0.00088139996,0.00028611632,0.0005575491,0.0002569812,0.0002042976,0.00060033664,0.00025990876,0.00043127165,0.0002020042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002111298,0.00012558213,0.00391454,0.0002528862,0.000045618235,0.0001696058,0.000076680466,0.08978381,0.88247424,0.001138982,0.00029676865,0.021510012],"study_design_scores_gemma":[0.000022040107,0.0001562239,0.002071711,0.000007140392,0.00002134168,0.00012407466,0.000012962816,0.58328265,0.41324538,0.00014911327,0.0008921304,0.000015164696],"about_ca_topic_score_codex":0.0027744265,"about_ca_topic_score_gemma":0.0018080118,"teacher_disagreement_score":0.0027744265,"about_ca_system_score_codex":0.00054264744,"about_ca_system_score_gemma":0.0004993137,"threshold_uncertainty_score":0.005516529},"labels":[],"label_agreement":null},{"id":"W2947503145","doi":"10.1007/s11095-019-2648-x","title":"Correction to: Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics","year":2019,"lang":"en","type":"erratum","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Pharmaceutics; Kinetics; Pharmaceutical technology; Solvent; Spray drying; Chemistry; Evaporation; Chromatography; Pharmacology; Organic chemistry; Medicine; Thermodynamics; Physics","score_opus":0.27236321403348523,"score_gpt":0.4559530751020361,"score_spread":0.18358986106855085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947503145","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000109433146,0.00079696084,0.0008836831,0.012655576,0.98210114,0.000025969832,0.00090803637,0.0005101177,0.0020090872],"genre_scores_gemma":[0.015133252,0.0098220445,0.013663655,0.04724293,0.4538176,0.00032258884,0.0055657425,0.0054623196,0.44896984],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99331737,0.0007952841,0.0011555491,0.0008198619,0.0034295467,0.0004822897],"domain_scores_gemma":[0.9527797,0.0062067118,0.002182528,0.0032516732,0.03340796,0.0021713865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0038953,0.0036023636,0.002742749,0.0073423195,0.0036992128,0.005371908,0.004407093,0.007256496,0.10286541],"category_scores_gemma":[0.05592228,0.0016917782,0.0024395299,0.003902274,0.002334777,0.0031256552,0.002918005,0.008226297,0.069323555],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043570715,0.000009683374,0.00005843348,0.0001452752,0.000009549025,0.00013942164,0.000014875512,0.00007605705,0.000073869094,0.0004826782,0.99198055,0.0069660614],"study_design_scores_gemma":[0.000043844342,0.000021830114,0.0005572854,0.00022392272,0.000028746308,0.000448271,0.000046784804,0.000569982,0.00058557134,0.001295421,0.996139,0.000039342725],"about_ca_topic_score_codex":0.019100012,"about_ca_topic_score_gemma":0.02401716,"teacher_disagreement_score":0.10286541,"about_ca_system_score_codex":0.004864831,"about_ca_system_score_gemma":0.007097436,"threshold_uncertainty_score":0.34411907},"labels":[],"label_agreement":null},{"id":"W2954407538","doi":"10.1007/s11095-019-2654-z","title":"Recent Treatment Advances and the Role of Nanotechnology, Combination Products, and Immunotherapy in Changing the Therapeutic Landscape of Acute Myeloid Leukemia","year":2019,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Surgical Specialties (Canada); Spinal Cord Injury BC; University of British Columbia; Canadian Centre for Applied Research in Cancer Control; BC Cancer Agency","funders":"","keywords":"Myeloid leukemia; Immunotherapy; Medicine; Leukemia; Nanotechnology; Cancer research; Immunology; Immune system; Materials science","score_opus":0.10853797583573603,"score_gpt":0.45660486645175563,"score_spread":0.3480668906160196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954407538","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017584932,0.99825114,0.00008687192,0.00034822346,0.00014899464,0.0000031726797,0.000011799396,0.0000052104715,0.0009686884],"genre_scores_gemma":[0.0007745119,0.9984041,0.000131674,0.0002176283,0.00013331966,0.000003873721,0.00001540699,9.540428e-7,0.00031846893],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99976283,0.000046999354,0.00003812001,0.000040640894,0.00008938009,0.000022023114],"domain_scores_gemma":[0.9996401,0.00019774288,0.000046704605,0.000009384181,0.00008504953,0.00002101649],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058418955,0.0004648241,0.00076677266,0.0019307,0.00025491795,0.00087685854,0.00046437368,0.0008661436,0.0028279193],"category_scores_gemma":[0.00081299536,0.0001864164,0.00049795647,0.0018303712,0.00036839608,0.001209982,0.0005005963,0.0012606628,0.0009277835],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007858884,0.000075616575,0.00023206761,0.02960031,0.0000917059,0.00023695367,0.000109858534,0.0004245273,0.0023183455,0.0066418964,0.023142071,0.9370481],"study_design_scores_gemma":[0.00001167381,0.00010836704,0.0006661402,0.0033833953,0.00011733663,0.0009909419,0.00007084167,0.000101658894,0.0005251857,0.0016770655,0.9923327,0.000014719563],"about_ca_topic_score_codex":0.0010307246,"about_ca_topic_score_gemma":0.0016430559,"teacher_disagreement_score":0.0028279193,"about_ca_system_score_codex":0.0005791887,"about_ca_system_score_gemma":0.001098764,"threshold_uncertainty_score":0.00946033},"labels":[],"label_agreement":null},{"id":"W2997063991","doi":"10.1007/s11095-019-2724-2","title":"Novel Approach for the Bioequivalence Assessment of Topical Cream Formulations: Model-Based Analysis of Tape Stripping Data Correctly Concludes BE and BIE","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université de Montréal","funders":"","keywords":"Bioequivalence; Stratum corneum; Pharmacokinetics; Mathematics; Chromatography; Medicine; Stripping (fiber); Pharmacology; Chemistry; Materials science","score_opus":0.7521730440483944,"score_gpt":0.6327760426779995,"score_spread":0.11939700137039488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997063991","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11620706,0.0012538276,0.8781184,0.0003399931,0.00009772472,0.00018802831,0.0005148233,0.0007864382,0.002493654],"genre_scores_gemma":[0.7730136,0.0010767881,0.22053708,0.00029037546,0.000045516197,0.0002778657,0.0006135833,0.00018639247,0.0039588343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989196,0.00043504863,0.000046305275,0.00016674248,0.00038535232,0.00004690153],"domain_scores_gemma":[0.99941444,0.00029498278,0.00007923212,0.00009154145,0.000105326086,0.0000145022605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019654976,0.0006165681,0.001059418,0.00078880956,0.00034701664,0.001159925,0.0006642523,0.0011437045,0.001268789],"category_scores_gemma":[0.0028054083,0.0003487254,0.0013807412,0.00047702694,0.00023266509,0.0008084429,0.00047832145,0.0012834241,0.0006030483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013890571,0.0011264645,0.0055855257,0.0007152299,0.00068101235,0.00029877553,0.00020348458,0.1138386,0.59575653,0.01322548,0.0031166489,0.26406327],"study_design_scores_gemma":[0.000044977245,0.0007646667,0.00469845,0.000035222434,0.00020449213,0.00056464516,0.000046775316,0.90011877,0.08610457,0.002948171,0.0043907035,0.00007855347],"about_ca_topic_score_codex":0.0022095093,"about_ca_topic_score_gemma":0.0026500206,"teacher_disagreement_score":0.0022095093,"about_ca_system_score_codex":0.0005206009,"about_ca_system_score_gemma":0.00097084424,"threshold_uncertainty_score":0.010394633},"labels":[],"label_agreement":null},{"id":"W2999659647","doi":"10.1007/s11095-019-2743-z","title":"Efficacy of Optimized Treatment Protocol Using LAU-7b Formulation against Ovalbumin (OVA) and House Dust Mite (HDM) -Induced Allergic Asthma in Atopic Hyperresponsive A/J Mice","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre; McGill University; McGill University Health Centre","funders":"","keywords":"Ovalbumin; House dust mite; Asthma; Medicine; Allergy; Immunology; Pyroglyphidae; Allergen; Immune system","score_opus":0.27262701614898016,"score_gpt":0.4908764319292221,"score_spread":0.21824941578024193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999659647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930782,0.0022239385,0.0018793198,0.00022937353,0.00033057455,0.0002141108,0.0007965361,0.00012998458,0.0011179796],"genre_scores_gemma":[0.98510474,0.00232904,0.005191178,0.00024298424,0.000118301185,0.00043814126,0.0012054103,0.000036960555,0.0053332415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998318,0.000022063039,0.000014852641,0.000037960006,0.00004173124,0.00005152359],"domain_scores_gemma":[0.9999254,0.000009160217,0.000019772451,0.0000072980583,0.000013516394,0.00002488683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020359889,0.00037237295,0.00045804013,0.0002701691,0.00017686568,0.00020932531,0.0003387391,0.0005806634,0.0017453748],"category_scores_gemma":[0.00010322627,0.00013431162,0.0003963813,0.00013056882,0.00026927728,0.00024260565,0.000100602854,0.0009917524,0.00038518023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027941873,0.0014267922,0.00013075289,0.00012935979,0.000016140168,0.00005000265,0.000018356253,0.00016760414,0.99080175,0.000075040676,0.0002655954,0.0041244067],"study_design_scores_gemma":[0.00042120583,0.012261629,0.0025909701,0.000017837825,0.000102445105,0.00012412573,0.000034121524,0.00084904185,0.98027074,0.000054688633,0.003254915,0.000018300343],"about_ca_topic_score_codex":0.00051841215,"about_ca_topic_score_gemma":0.0007230224,"teacher_disagreement_score":0.0017453748,"about_ca_system_score_codex":0.00015682078,"about_ca_system_score_gemma":0.00025884216,"threshold_uncertainty_score":0.005838871},"labels":[],"label_agreement":null},{"id":"W3002032475","doi":"10.1007/s11095-019-2684-6","title":"Dual-Targeted Delivery of Nanoparticles Encapsulating Paclitaxel and Everolimus: a Novel Strategy to Overcome Breast Cancer Receptor Heterogeneity","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Paclitaxel; Everolimus; Breast cancer; Drug delivery; Pharmacology; Medicine; Targeted drug delivery; Cancer; Cancer research; Chemistry; Oncology; Nanotechnology; Drug; Internal medicine; Materials science","score_opus":0.18186391545524994,"score_gpt":0.4237751218094143,"score_spread":0.24191120635416435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3002032475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9317709,0.0041975593,0.058090873,0.00058313645,0.00011883379,0.00008539627,0.00010748134,0.0002503971,0.00479538],"genre_scores_gemma":[0.9755086,0.0013068256,0.018199552,0.00018037666,0.000020337982,0.000049455877,0.000079145975,0.000039382012,0.0046163565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992454,0.000009250508,0.000003945747,0.000024068639,0.000017967244,0.000020175221],"domain_scores_gemma":[0.99996746,0.0000051064735,0.000009622311,0.000003480712,0.0000062725926,0.00000797091],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013839825,0.00029268334,0.00023487501,0.00017549572,0.00014443646,0.00034319708,0.00022929281,0.00043229037,0.0003427712],"category_scores_gemma":[0.00009100211,0.00015146134,0.00017059749,0.000095022755,0.00018455107,0.0003539297,0.00032274835,0.00037219177,0.0001788536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040305335,0.000019122175,0.00002973908,0.0000273455,0.0000050267085,0.000034347646,0.000014281817,0.0001520327,0.9954627,0.00051783264,0.00010413084,0.0035931685],"study_design_scores_gemma":[0.000014446537,0.00009075505,0.0001987969,0.000002814893,0.000015633306,0.00015591417,0.000009497647,0.0029555585,0.99188304,0.000082089486,0.004585429,0.0000060378657],"about_ca_topic_score_codex":0.0003660856,"about_ca_topic_score_gemma":0.0007151101,"teacher_disagreement_score":0.00043229037,"about_ca_system_score_codex":0.00031347954,"about_ca_system_score_gemma":0.00019359103,"threshold_uncertainty_score":0.0022744536},"labels":[],"label_agreement":null},{"id":"W3003023553","doi":"10.1007/s11095-019-2730-4","title":"Design and Characterization of Injectable Poly(Lactic-Co-Glycolic Acid) Pastes for Sustained and Local Drug Release","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"","keywords":"Drug; Pharmacokinetics; Pharmacology; In vivo; Drug delivery; Chemistry; Biomedical engineering; Glycolic acid; Lidocaine; Viscosity; PLGA; Materials science; Lactic acid; In vitro; Medicine; Surgery; Organic chemistry; Biochemistry; Composite material","score_opus":0.2672241019776112,"score_gpt":0.5090186159868051,"score_spread":0.24179451400919388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003023553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8818673,0.0020575738,0.11190021,0.0001605683,0.00014034125,0.0004916826,0.00043265987,0.00044282395,0.0025068962],"genre_scores_gemma":[0.93254936,0.00069936586,0.06272754,0.00008521962,0.00003007687,0.00025978463,0.00024245575,0.000113061215,0.0032931885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973077,0.000022037784,0.000028452945,0.00006469006,0.00013102868,0.000023084347],"domain_scores_gemma":[0.99969053,0.000051260587,0.00011873461,0.000027506985,0.00007752433,0.00003447504],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003665763,0.00031401828,0.00028891038,0.00033530986,0.00013219303,0.0003879773,0.0003142989,0.0004258048,0.0006807298],"category_scores_gemma":[0.0005696996,0.00028887953,0.00027003366,0.00017977465,0.0002503638,0.0004193128,0.00012813642,0.0003850767,0.00031216283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023001034,0.000021540458,0.000039797444,0.000030082858,0.0000015945793,0.000022107793,0.000006996372,0.000099755314,0.997835,0.00003822012,0.000014269101,0.0018677973],"study_design_scores_gemma":[0.00001305414,0.00025450398,0.00081642985,0.000002598609,0.00000803983,0.000059308662,0.0000048267125,0.0016333418,0.9965798,0.0000151684635,0.00060862955,0.0000041761837],"about_ca_topic_score_codex":0.00015715968,"about_ca_topic_score_gemma":0.00032595472,"teacher_disagreement_score":0.0006807298,"about_ca_system_score_codex":0.0002173802,"about_ca_system_score_gemma":0.00020111229,"threshold_uncertainty_score":0.0022773147},"labels":[],"label_agreement":null},{"id":"W3005371039","doi":"10.1007/s11095-020-2770-9","title":"Enabling Combinatorial siRNA Delivery against Apoptosis-Related Proteins with Linoleic Acid and α-Linoleic Acid Substituted Low Molecular Weight Polyethylenimines","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Small interfering RNA; Survivin; Gene silencing; Chemistry; Apoptosis; Biochemistry; Molecular biology; Cancer research; RNA; Biology; Gene","score_opus":0.052954481371250306,"score_gpt":0.3383517513580907,"score_spread":0.2853972699868404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005371039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95557255,0.0022284482,0.036933225,0.000107804706,0.00006686435,0.00016884615,0.00031599443,0.0003781069,0.004228059],"genre_scores_gemma":[0.9752144,0.0009518819,0.01874526,0.00009449441,0.000011218734,0.00014574463,0.00022595943,0.00006394684,0.0045471205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998116,0.000029465884,0.000018422441,0.0000512106,0.00005244378,0.00003689434],"domain_scores_gemma":[0.99987864,0.000023554085,0.00004484708,0.000011147808,0.00001744901,0.000024369192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022568127,0.00046432324,0.00030851125,0.0002700903,0.00015758029,0.00048896956,0.00028797757,0.00043974823,0.00063930324],"category_scores_gemma":[0.00016977265,0.0002282134,0.00030124927,0.00021274673,0.00023452504,0.00034464416,0.00035719687,0.00040483233,0.00041350012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050413466,0.0000065931918,0.000025651472,0.000023107505,0.000004800383,0.00002349836,0.0000061231535,0.000090917216,0.99870956,0.00018277527,0.000013276839,0.0008634199],"study_design_scores_gemma":[0.0000071282325,0.000057715868,0.00016164493,0.0000014733105,0.000009225393,0.00004234669,0.0000028474467,0.0005329018,0.99812967,0.000023638546,0.0010281682,0.000003156932],"about_ca_topic_score_codex":0.00028799297,"about_ca_topic_score_gemma":0.000677994,"teacher_disagreement_score":0.00063930324,"about_ca_system_score_codex":0.00047490405,"about_ca_system_score_gemma":0.000222375,"threshold_uncertainty_score":0.003445685},"labels":[],"label_agreement":null},{"id":"W3042339997","doi":"10.1007/s11095-020-02836-6","title":"Dicationic Amino Substituted Gemini Surfactants and their Nanoplexes: Improved Synthesis and Characterization of Transfection Efficiency and Corneal Penetration In Vitro","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Zeta potential; Dynamic light scattering; Transfection; Pulmonary surfactant; Chemistry; Gene delivery; Surface charge; Nuclear chemistry; Cytotoxicity; Biophysics; Chromatography; Nanoparticle; Materials science; In vitro; Nanotechnology; Biochemistry; Biology; Physical chemistry","score_opus":0.07111661075939239,"score_gpt":0.3507510230973036,"score_spread":0.2796344123379112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042339997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825728,0.002089132,0.013622514,0.00009773129,0.000034022443,0.000051131097,0.00014589973,0.000100538644,0.0012863437],"genre_scores_gemma":[0.98223996,0.00094416365,0.013306305,0.000064509804,0.00000766283,0.00003813516,0.00027866548,0.00004118238,0.0030794977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974614,0.00005447699,0.000034549306,0.000059506343,0.000075209435,0.000030095094],"domain_scores_gemma":[0.9996339,0.00007458433,0.00011453678,0.0000337271,0.00010123531,0.000041932246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046335917,0.00023821872,0.00017854656,0.00020616852,0.00013821322,0.00026132658,0.00019107643,0.00037835355,0.00033879382],"category_scores_gemma":[0.0006514358,0.00015744376,0.000115608265,0.00027614157,0.00018538105,0.0003319403,0.00021616512,0.00031042757,0.00017704233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079692196,0.00000803926,0.00009070608,0.000024719742,0.0000044463573,0.000024855242,0.000032115295,0.00005857782,0.99774903,0.00013878102,0.00003176334,0.001757276],"study_design_scores_gemma":[0.0000035688677,0.00007393134,0.00024303471,0.0000011983957,0.0000071073077,0.000069899994,0.0000056690346,0.00045584436,0.99824905,0.000013417215,0.00087431766,0.0000029618711],"about_ca_topic_score_codex":0.00058652216,"about_ca_topic_score_gemma":0.0008398211,"teacher_disagreement_score":0.00058652216,"about_ca_system_score_codex":0.00034192376,"about_ca_system_score_gemma":0.00018247428,"threshold_uncertainty_score":0.002480805},"labels":[],"label_agreement":null},{"id":"W3042346442","doi":"10.1007/s11095-020-02876-y","title":"Machine Learning Platform to Discover Novel Growth Inhibitors of Neisseria gonorrhoeae","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Aegera Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Neisseria gonorrhoeae; chEMBL; Drug discovery; Workflow; In silico; Machine learning; Small molecule; Computational biology; Computer science; Virtual screening; Artificial intelligence; Chemistry; Bioinformatics; Biology; Microbiology; Biochemistry; Database","score_opus":0.14689420488819854,"score_gpt":0.3966117669413303,"score_spread":0.24971756205313178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042346442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5961805,0.00941572,0.29653957,0.003330791,0.0009909276,0.0008996631,0.022322487,0.031823028,0.03849733],"genre_scores_gemma":[0.70745134,0.003940305,0.2472652,0.0008610665,0.00016957251,0.0005508193,0.02479822,0.00032225056,0.014641155],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99989927,0.00001443836,0.0000055043615,0.000026620159,0.000036933692,0.000017277554],"domain_scores_gemma":[0.99990547,0.00003499633,0.000016859987,0.000008902638,0.000020675814,0.0000131797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029582396,0.00049706566,0.000433133,0.0005530819,0.00020547971,0.000639593,0.0003557812,0.00038564205,0.0028732915],"category_scores_gemma":[0.00044657005,0.00015067527,0.0004946464,0.0003211495,0.000090003945,0.0003002406,0.00031237182,0.0006283125,0.00088276196],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015075691,0.0017754919,0.011129564,0.0010688176,0.0005171151,0.0006675617,0.00007339387,0.097709365,0.33221126,0.01041527,0.036352936,0.5065717],"study_design_scores_gemma":[0.00019778762,0.0009875188,0.004361673,0.00006401255,0.00026191285,0.00027883827,0.000042009447,0.7804423,0.15286711,0.007585316,0.052867576,0.000044021912],"about_ca_topic_score_codex":0.00068969565,"about_ca_topic_score_gemma":0.0010832079,"teacher_disagreement_score":0.0028732915,"about_ca_system_score_codex":0.00032772205,"about_ca_system_score_gemma":0.0005632409,"threshold_uncertainty_score":0.009612143},"labels":[],"label_agreement":null},{"id":"W3043613626","doi":"10.1007/s11095-020-02877-x","title":"Residual Solvents in Nanomedicine and Lipid-Based Drug Delivery Systems: a Case Study to Better Understand Processes","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Mitacs; Agence Nationale de la Recherche","keywords":"Nanomedicine; Solvent; Drug delivery; Ultrafiltration (renal); Nanoparticle; Chromatography; Liposome; Chemistry; Size-exclusion chromatography; Nanotechnology; Materials science; Organic chemistry","score_opus":0.1995830814786568,"score_gpt":0.4313833964442627,"score_spread":0.2318003149656059,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043613626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9545553,0.00802786,0.020997766,0.00060438603,0.000063638334,0.0001996517,0.00018626559,0.00014090576,0.015224188],"genre_scores_gemma":[0.9801876,0.00284756,0.008938455,0.000102434846,0.000018839295,0.0000375277,0.00005684999,0.00005638838,0.007754468],"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","domain_scores_codex":[0.998771,0.00044610878,0.00006497762,0.00012753901,0.00043195853,0.00015830912],"domain_scores_gemma":[0.9990865,0.00056563487,0.00013068711,0.00007197679,0.00010826832,0.00003699095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011173217,0.00038830258,0.0004131867,0.00056648086,0.0011170316,0.0016796755,0.00053780514,0.0014002649,0.0017312989],"category_scores_gemma":[0.0015103488,0.00013275212,0.00042990316,0.00054099015,0.0009795378,0.0011037593,0.00081454666,0.00048470212,0.0006831673],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024779304,0.0012743997,0.015387853,0.0035773648,0.00007593726,0.023127787,0.006246789,0.022931287,0.7055286,0.024002464,0.0025327657,0.19283682],"study_design_scores_gemma":[0.00004557999,0.0013301371,0.0027055792,0.00017867784,0.00011915162,0.0064823916,0.0032579834,0.01200795,0.91683686,0.0017818598,0.05520079,0.000053100048],"about_ca_topic_score_codex":0.002115355,"about_ca_topic_score_gemma":0.00283913,"teacher_disagreement_score":0.002115355,"about_ca_system_score_codex":0.0009374504,"about_ca_system_score_gemma":0.0007075348,"threshold_uncertainty_score":0.006801665},"labels":[],"label_agreement":null},{"id":"W3087062476","doi":"10.1007/s11095-020-02892-y","title":"RETRACTED ARTICLE: Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell Progression","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Graphene and Nanomaterials Applications","field":"Engineering","cited_by":52,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Tabriz University of Medical Sciences","keywords":"Cyclin-dependent kinase; Cancer research; Cancer cell; Cell cycle; Chemistry; Cell growth; Tumor microenvironment; Tumor progression; Cancer; Cell; Biology; Biochemistry","score_opus":0.07250599021903405,"score_gpt":0.37682869116919876,"score_spread":0.3043227009501647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3087062476","genre_codex":"editorial","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07559492,0.027535914,0.014671939,0.18648453,0.6706755,0.00016314215,0.0045046858,0.00379221,0.01657726],"genre_scores_gemma":[0.37349704,0.024855163,0.019699933,0.11892388,0.06748921,0.0002296197,0.008370214,0.0014659038,0.3854691],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992004,0.00007288488,0.000101234655,0.00009214558,0.00041015522,0.0001232642],"domain_scores_gemma":[0.9980731,0.0007350231,0.00023504726,0.00013027358,0.0005787875,0.00024765072],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008403855,0.0006757228,0.0006426751,0.0008415446,0.0008213819,0.0008581443,0.0010111401,0.0037719626,0.015978932],"category_scores_gemma":[0.0040851003,0.0002979167,0.0005653067,0.00049662567,0.00068146526,0.00073927734,0.00062038744,0.0020640562,0.0077435067],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018236903,0.00017894618,0.0022423079,0.0010394736,0.00014799916,0.01736403,0.00026719028,0.00031674668,0.05720042,0.0015519961,0.7822981,0.13556911],"study_design_scores_gemma":[0.00011129186,0.00036961262,0.005042049,0.00014877338,0.00018195355,0.01414342,0.00024063885,0.001230011,0.119729534,0.0010611147,0.8576579,0.000083612504],"about_ca_topic_score_codex":0.0015262077,"about_ca_topic_score_gemma":0.0025655876,"teacher_disagreement_score":0.99622804,"about_ca_system_score_codex":0.0009115392,"about_ca_system_score_gemma":0.0010464261,"threshold_uncertainty_score":0.053454876},"labels":[],"label_agreement":null},{"id":"W3089777532","doi":"10.1007/s11095-020-02924-7","title":"Combined in Vitro-in Silico Approach to Predict Deposition and Pharmacokinetics of Budesonide Dry Powder Inhalers","year":2020,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Pharmacokinetics; Budesonide; Dry-powder inhaler; Mucociliary clearance; Deposition (geology); In vivo; Physiologically based pharmacokinetic modelling; Pharmacology; Inhaler; Dissolution testing; In silico; Chemistry; Absorption (acoustics); Biomedical engineering; Materials science; Lung; Medicine; Inhalation; Anesthesia; Asthma; Internal medicine; Biochemistry","score_opus":0.13770588341180626,"score_gpt":0.4195048603854803,"score_spread":0.28179897697367406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3089777532","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83509105,0.0034919083,0.15194607,0.0002558282,0.00012346682,0.0001978879,0.001930775,0.0010505434,0.0059124636],"genre_scores_gemma":[0.9757849,0.00090901327,0.02083112,0.00006086932,0.00002152413,0.000073678995,0.0005693469,0.000048221074,0.0017013112],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9997658,0.00006347579,0.000022275684,0.000044026387,0.00008280368,0.000021543296],"domain_scores_gemma":[0.99956375,0.0002688059,0.000051550178,0.000020850372,0.00007833732,0.000016656151],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049363205,0.00060180353,0.000908443,0.0004676422,0.00023997245,0.0009833106,0.00047868793,0.0010867977,0.0010577757],"category_scores_gemma":[0.0007464955,0.0005715578,0.0010190979,0.0002294564,0.00015409323,0.00027488754,0.0002726733,0.0003924445,0.0005047931],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006347585,0.0005055422,0.012697132,0.0006943432,0.0004351537,0.000634905,0.00007447527,0.7660912,0.18997975,0.0006566437,0.00077785435,0.026818233],"study_design_scores_gemma":[0.000031533833,0.00023977197,0.002158482,0.000010298502,0.00011565471,0.00016878787,0.00002149961,0.9655365,0.030779932,0.00012924284,0.0007907523,0.000017649127],"about_ca_topic_score_codex":0.005922798,"about_ca_topic_score_gemma":0.005806046,"teacher_disagreement_score":0.005922798,"about_ca_system_score_codex":0.00042553456,"about_ca_system_score_gemma":0.0005415427,"threshold_uncertainty_score":0.011776626},"labels":[],"label_agreement":null},{"id":"W3120737753","doi":"10.1007/s11095-020-02976-9","title":"Evaluation of Intranasal Vaccine Delivery Using Anatomical Replicas of Infant Nasal Airways","year":2021,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi Pasteur","keywords":"Nasal administration; Medicine; Pharmaceutical technology; Delivery system; Immunology; Pharmacology; Chemistry","score_opus":0.5519647663885795,"score_gpt":0.6135277686755074,"score_spread":0.061563002286927904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120737753","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99504894,0.0008961027,0.003528363,0.000024731333,0.000038308877,0.000058632788,0.000062397434,0.00002800418,0.0003146189],"genre_scores_gemma":[0.9949201,0.0006439189,0.0036788315,0.000015059052,0.000006549266,0.000032289787,0.00010423201,0.000010353095,0.0005886804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99972004,0.00007871025,0.000022771359,0.00005304583,0.000072288814,0.0000531089],"domain_scores_gemma":[0.99962497,0.0001800363,0.000049594524,0.000046880697,0.00007337373,0.000025136733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006084907,0.00036437932,0.00025700105,0.00015044428,0.00015320042,0.00024611712,0.00032684495,0.00046570555,0.00061137177],"category_scores_gemma":[0.0007106403,0.00015222117,0.00030548402,0.000102549304,0.00024032943,0.00033856992,0.00015852311,0.0002875641,0.00017354282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015386773,0.000055706154,0.0001889051,0.000048567665,0.0000049154996,0.00004777964,0.00003723741,0.000279189,0.9974444,0.000029377596,0.000008927207,0.0017012279],"study_design_scores_gemma":[0.000009791423,0.0030383081,0.000953417,0.0000047516774,0.00002524573,0.00007843891,0.000059122074,0.0017895751,0.9936521,0.000011772521,0.00037329187,0.000004203807],"about_ca_topic_score_codex":0.00088850904,"about_ca_topic_score_gemma":0.00067819626,"teacher_disagreement_score":0.00088850904,"about_ca_system_score_codex":0.00016227108,"about_ca_system_score_gemma":0.00022636422,"threshold_uncertainty_score":0.0032180548},"labels":[],"label_agreement":null},{"id":"W3128385432","doi":"10.1007/s11095-021-02990-5","title":"Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats","year":2021,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Deanship of Scientific Research, King Saud University","keywords":"Pharmacokinetics; Micelle; Chemistry; Biodistribution; Pharmacology; Distribution (mathematics); Ethylene oxide; Dosage form; In vivo; Bioavailability; Oral administration; Caprolactone; Chromatography; In vitro; Medicine; Biochemistry; Organic chemistry; Biology","score_opus":0.27934658939666435,"score_gpt":0.5332680578453187,"score_spread":0.2539214684486544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128385432","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99529254,0.0011173167,0.0016497932,0.00010527692,0.000091058326,0.000053801064,0.00044124847,0.00012620057,0.0011228793],"genre_scores_gemma":[0.98928857,0.0015730738,0.0015962073,0.00006736961,0.000053378237,0.000089682646,0.0004613892,0.000042420525,0.0068278867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983203,0.000024267962,0.000010650023,0.000047377263,0.000029623176,0.00005605137],"domain_scores_gemma":[0.9997309,0.00006392689,0.000075411255,0.000026378948,0.00002834886,0.00007495238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026883223,0.00057100377,0.0004985404,0.00040919808,0.0002082801,0.00034866575,0.00032092122,0.00049546483,0.0012336341],"category_scores_gemma":[0.00028858194,0.00031040597,0.00036038848,0.0002907762,0.0004622985,0.0006006646,0.00009158845,0.001093617,0.0004981694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024023645,0.0019183866,0.0006708303,0.00013916269,0.000062115425,0.00013437484,0.00011225662,0.0018516611,0.9574031,0.00030873794,0.00033903043,0.013036677],"study_design_scores_gemma":[0.00062543136,0.027968353,0.0047126412,0.000012730181,0.00019761929,0.00017120068,0.000079726255,0.004602426,0.9596284,0.00015450371,0.0018051269,0.000041902986],"about_ca_topic_score_codex":0.0022809966,"about_ca_topic_score_gemma":0.0025605042,"teacher_disagreement_score":0.0022809966,"about_ca_system_score_codex":0.0004774946,"about_ca_system_score_gemma":0.0008182571,"threshold_uncertainty_score":0.0045354366},"labels":[],"label_agreement":null},{"id":"W3130411672","doi":"10.1007/s11095-021-03007-x","title":"Traditional Chinese Medicine “Pill”, an Ancient Dosage Form with Surprising Modern Pharmaceutical Characteristics","year":2021,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Plant-based Medicinal Research","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Mitacs","keywords":"Pill; Medicine; Traditional Chinese medicine; Traditional medicine; Dosage form; Alternative medicine; Pharmacology","score_opus":0.6876648503864344,"score_gpt":0.6411957449066864,"score_spread":0.04646910547974803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130411672","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001132748,0.99368626,0.0005140705,0.00037751568,0.00024672618,0.000017168397,0.00010566199,0.0000195093,0.0039002884],"genre_scores_gemma":[0.0059148255,0.9904322,0.0007531566,0.00036642616,0.00024353973,0.000012673407,0.00013274771,0.0000036691742,0.002140775],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999198,0.000010289538,0.000010229796,0.00001823952,0.000034393943,0.0000069699163],"domain_scores_gemma":[0.9999012,0.000050440896,0.000014398965,0.000003951657,0.000022060933,0.000007984669],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002139155,0.00073576183,0.0008184606,0.0016347987,0.0002679157,0.0007140451,0.00047968663,0.000473288,0.003995746],"category_scores_gemma":[0.0002608235,0.00018079471,0.0003202549,0.0018430382,0.00042319452,0.00084295595,0.0004097344,0.0011483993,0.0010360789],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008788023,0.00008959369,0.00023352783,0.021777099,0.00009156374,0.00028588917,0.000090889655,0.0002530855,0.008034617,0.0058244434,0.011634549,0.95159686],"study_design_scores_gemma":[0.00004122414,0.00017361606,0.002636447,0.002255691,0.000257804,0.001641098,0.00010402296,0.00017968912,0.0033011723,0.0026796346,0.98668796,0.000041640284],"about_ca_topic_score_codex":0.00119276,"about_ca_topic_score_gemma":0.0033424732,"teacher_disagreement_score":0.003995746,"about_ca_system_score_codex":0.0003117732,"about_ca_system_score_gemma":0.00063138845,"threshold_uncertainty_score":0.013367116},"labels":[],"label_agreement":null},{"id":"W3152045758","doi":"10.1007/s11095-021-03035-7","title":"Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model","year":2021,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Pharmacological Effects and Toxicity Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; Hospital for Sick Children","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Fexofenadine; Transplacental; Pharmacokinetics; Chemistry; Pharmacology; Terfenadine; Enantiomer; In vivo; Endocrinology; Fetus; Placenta; Stereochemistry; Medicine; Biology; Pregnancy","score_opus":0.24980641001454543,"score_gpt":0.5386343965172907,"score_spread":0.2888279865027453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3152045758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.982385,0.0076750536,0.0053399676,0.0004752843,0.0001111676,0.0000775398,0.0005285225,0.00011075627,0.0032967082],"genre_scores_gemma":[0.9922351,0.004244151,0.0016904993,0.00010884678,0.00002439983,0.00003681883,0.0002174872,0.000027186252,0.001415456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998264,0.00006623148,0.000005554852,0.00004066015,0.000032408316,0.00002879337],"domain_scores_gemma":[0.99982846,0.00006251582,0.000036116675,0.000031218544,0.000014947341,0.000026745935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034199384,0.00028382897,0.00037578255,0.00021436284,0.0002114065,0.00064685155,0.00025706037,0.0003024369,0.001666679],"category_scores_gemma":[0.0006092306,0.0001925441,0.00028032853,0.00022234427,0.00035687213,0.00058022887,0.0002104175,0.00084624713,0.00021482362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.028037656,0.0008220048,0.008085229,0.0005573931,0.00021274171,0.0023121543,0.00058824354,0.002063609,0.8829711,0.0021952344,0.0017938317,0.070360795],"study_design_scores_gemma":[0.0009424381,0.014888342,0.028308623,0.0000712282,0.00070343964,0.0034451475,0.0010575472,0.019418694,0.9124356,0.0008553373,0.017792197,0.00008155589],"about_ca_topic_score_codex":0.0063334997,"about_ca_topic_score_gemma":0.004889951,"teacher_disagreement_score":0.0063334997,"about_ca_system_score_codex":0.00067203667,"about_ca_system_score_gemma":0.001061129,"threshold_uncertainty_score":0.012593269},"labels":[],"label_agreement":null},{"id":"W315389191","doi":"10.1023/a:1024454105124","title":"Cyclosporine binds to the neutral lipid and potentially other binding sites of lipid transfer protein I.","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Oral and gingival health research","field":"Health Professions","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Liposome; Plant lipid transfer proteins; Chemistry; Long-term potentiation; Fast protein liquid chromatography; Biophysics; Free fraction; Biochemistry; Chromatography; Plasma protein binding; High-performance liquid chromatography; Receptor; Biology","score_opus":0.3919269005833782,"score_gpt":0.5826010568956073,"score_spread":0.19067415631222906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W315389191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9117414,0.033862215,0.014570382,0.001412587,0.0003095756,0.00014982051,0.00027595658,0.00023186827,0.037446138],"genre_scores_gemma":[0.9715996,0.009146803,0.004618087,0.0004953203,0.00015254399,0.000039118037,0.00029884302,0.0000295746,0.013620186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963284,0.00010749898,0.00001136392,0.00006720605,0.00009923596,0.00008179924],"domain_scores_gemma":[0.99941695,0.00017604762,0.00014586803,0.000030917174,0.00005611901,0.00017421877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032498597,0.00034008792,0.00030606356,0.0003617247,0.0007143122,0.0006023834,0.00036745644,0.00060845853,0.006457959],"category_scores_gemma":[0.00074625085,0.00014166495,0.00030686238,0.00039706356,0.00046865654,0.00026355198,0.0004151066,0.0006146855,0.0017669584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033931865,0.0000751011,0.00230681,0.00019551192,0.00004853759,0.00021007539,0.00006739175,0.00013963642,0.9788608,0.0008544001,0.00077592814,0.016126513],"study_design_scores_gemma":[0.00011045256,0.0011652928,0.021016484,0.00006480644,0.00007055493,0.0014171012,0.00018735364,0.0008167833,0.9370932,0.000600663,0.037429318,0.000027940205],"about_ca_topic_score_codex":0.0025073576,"about_ca_topic_score_gemma":0.0022806202,"teacher_disagreement_score":0.006457959,"about_ca_system_score_codex":0.00064699363,"about_ca_system_score_gemma":0.00057797495,"threshold_uncertainty_score":0.021604002},"labels":[],"label_agreement":null},{"id":"W3198913869","doi":"10.1007/s11095-021-03082-0","title":"Using Filters to Estimate Regional Lung Deposition with Dry Powder Inhalers","year":2021,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Deposition (geology); Filter (signal processing); Aerosolization; Inhalation; Filtration (mathematics); Dry-powder inhaler; Cascade impactor; Aerosol; Environmental science; Chemistry; Materials science; Biomedical engineering; Nanotechnology; Medicine; Computer science; Inhaler; Anesthesia; Geology; Mathematics; Organic chemistry","score_opus":0.28741971382273634,"score_gpt":0.5374127125665945,"score_spread":0.24999299874385816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198913869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.58786625,0.0059937583,0.40013105,0.00014709421,0.00012628312,0.0002696137,0.0011384389,0.0011617166,0.0031657715],"genre_scores_gemma":[0.87120897,0.002427045,0.122554615,0.00019235123,0.000053677555,0.00017093934,0.000682445,0.00025701983,0.0024528722],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992052,0.00016405199,0.000035958106,0.00024136722,0.00030573865,0.000047669742],"domain_scores_gemma":[0.9991416,0.0004600058,0.00013190176,0.000075942124,0.00016674961,0.000023892853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011948853,0.00071716023,0.00094954774,0.0014491156,0.00029870594,0.001319325,0.0006782622,0.0014995671,0.000598731],"category_scores_gemma":[0.0016542169,0.000515746,0.0010083157,0.0006149386,0.00022745093,0.0009978765,0.00034069802,0.00041160986,0.00056483457],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021322833,0.00023992408,0.12527059,0.0008363722,0.0013040049,0.00033986973,0.00026092163,0.04348436,0.67916745,0.0006135833,0.0011932604,0.14515734],"study_design_scores_gemma":[0.0001304452,0.0014103809,0.1868519,0.00011632747,0.0012994191,0.0010757435,0.00022154016,0.35819507,0.4440906,0.0008044075,0.0056337924,0.00017039044],"about_ca_topic_score_codex":0.0086660255,"about_ca_topic_score_gemma":0.006853923,"teacher_disagreement_score":0.0086660255,"about_ca_system_score_codex":0.0004997067,"about_ca_system_score_gemma":0.0005073959,"threshold_uncertainty_score":0.017231166},"labels":[],"label_agreement":null},{"id":"W3207336441","doi":"10.1007/s11095-021-03122-9","title":"Optimizing the Design of Blood–Brain Barrier-Penetrating Polymer-Lipid-Hybrid Nanoparticles for Delivering Anticancer Drugs to Glioblastoma","year":2021,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Doxorubicin; In vivo; Cytotoxicity; Blood–brain barrier; Glioma; Biodistribution; Chemistry; In vitro; Zeta potential; Pharmacology; Biophysics; Nanoparticle; Materials science; Cancer research; Nanotechnology; Biochemistry; Chemotherapy; Medicine; Biology; Central nervous system","score_opus":0.10396289087484928,"score_gpt":0.40495836131554297,"score_spread":0.3009954704406937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3207336441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9671513,0.0012777955,0.029142348,0.00014079535,0.000024575538,0.00010396222,0.000069540205,0.000088554116,0.0020011],"genre_scores_gemma":[0.97581744,0.00079454645,0.021943467,0.00006066457,0.0000066482185,0.00008676872,0.00008182563,0.00004112913,0.0011675234],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998994,0.000017043954,0.000008016533,0.000023498147,0.00002745766,0.000024690633],"domain_scores_gemma":[0.9999225,0.000014454208,0.00002429123,0.0000038088285,0.000022207307,0.000012764362],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023688088,0.00033889172,0.00020854002,0.00021836175,0.0001793632,0.00049515726,0.00023193154,0.00041052926,0.0004424373],"category_scores_gemma":[0.00029088184,0.00019653219,0.00024333467,0.00014979026,0.00015430893,0.00041056392,0.00024835367,0.00029902134,0.00029241003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008938742,0.000053739226,0.00015966107,0.00007369362,0.000008351325,0.00003691703,0.00002441014,0.0034644082,0.9914614,0.0005264077,0.00007004586,0.0040316167],"study_design_scores_gemma":[0.000026954795,0.00027995493,0.00041106407,0.00000788793,0.000027056807,0.000070169044,0.000025646035,0.020921592,0.9752653,0.00015037275,0.0027999005,0.000014073413],"about_ca_topic_score_codex":0.0007993227,"about_ca_topic_score_gemma":0.0015036844,"teacher_disagreement_score":0.0007993227,"about_ca_system_score_codex":0.0005556086,"about_ca_system_score_gemma":0.00046576947,"threshold_uncertainty_score":0.004031241},"labels":[],"label_agreement":null},{"id":"W321053608","doi":"10.1007/s11095-015-1702-6","title":"A Study of Liposomal Formulations to Improve the Delivery of Aquated Cisplatin to a Multidrug Resistant Tumor","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Toronto; Ontario Institute for Cancer Research","funders":"University of Toronto; Canadian Institutes of Health Research; Government of Ontario; University Health Network","keywords":"Liposome; Pharmacokinetics; Pharmacology; Chemistry; Cisplatin; Potency; In vitro; In vivo; Multiple drug resistance; Drug; Drug delivery; Metabolite; Biochemistry; Chemotherapy; Medicine; Biology; Internal medicine; Antibiotics","score_opus":0.21183947082250815,"score_gpt":0.45683908528953404,"score_spread":0.2449996144670259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W321053608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933901,0.0017677099,0.0034432677,0.000090682894,0.000028805154,0.00013966649,0.000040336807,0.000015473364,0.0010840014],"genre_scores_gemma":[0.99037325,0.0020050618,0.0049670953,0.000071742965,0.000014655768,0.000058125606,0.00006290033,0.000023844737,0.002423359],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998995,0.000028364244,0.000007965307,0.000026379774,0.000023599729,0.000014094017],"domain_scores_gemma":[0.9999149,0.000036945687,0.00001334671,0.0000067061696,0.000018995732,0.000009111793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003364591,0.00019441066,0.00021517272,0.00013415533,0.0001499965,0.00024547876,0.00016301425,0.00023994774,0.00085125567],"category_scores_gemma":[0.000324946,0.000119416356,0.00020250888,0.00009873315,0.00021089352,0.00039091602,0.00014277805,0.00029968977,0.00012694082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030216182,0.00016371589,0.000068447305,0.000102960694,0.000008438393,0.00006636335,0.000056192013,0.00031736307,0.99366647,0.00024924558,0.0000541862,0.004944417],"study_design_scores_gemma":[0.0000913689,0.0024661748,0.0006911599,0.0000061835526,0.000031595227,0.00012078099,0.000025530386,0.0019755908,0.99184567,0.000036545345,0.002701648,0.0000077245995],"about_ca_topic_score_codex":0.0006750749,"about_ca_topic_score_gemma":0.0005437101,"teacher_disagreement_score":0.00085125567,"about_ca_system_score_codex":0.00023210738,"about_ca_system_score_gemma":0.00022415846,"threshold_uncertainty_score":0.0028476715},"labels":[],"label_agreement":null},{"id":"W324176139","doi":"10.1023/a:1022664406840","title":"In Vitro Evaluation of Nebulization Properties, Antimicrobial Activity, and Regional Airway Surface Liquid Concentration of Liposomal Polymyxin B Sulfate","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Provincial Laboratory of Public Health; University of Alberta","funders":"Cystic Fibrosis Foundation","keywords":"In vitro; Liposome; Antimicrobial; Polymyxin B; Chemistry; Microbiology; Airway; Polymyxin; Chromatography; Pharmacology; Antibiotics; Medicine; Biochemistry; Biology; Anesthesia","score_opus":0.2400307381014827,"score_gpt":0.4507060059697368,"score_spread":0.2106752678682541,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W324176139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968928,0.0016216025,0.0010459123,0.000026856958,0.000012906366,0.000024045466,0.000074127005,0.000011709484,0.0002900015],"genre_scores_gemma":[0.99699354,0.0009872349,0.0010540487,0.000025155634,0.000014129238,0.00002262441,0.00016864865,0.000008344451,0.0007262293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99971586,0.00008242492,0.000026540654,0.000038887203,0.000082492006,0.000053708165],"domain_scores_gemma":[0.9996258,0.00017703949,0.00007278932,0.00003238782,0.000058428326,0.000033595727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058412773,0.000408598,0.00038587945,0.00015078897,0.00017942033,0.00023551974,0.00024107621,0.00035214206,0.0006720758],"category_scores_gemma":[0.0004676179,0.00023503497,0.00038233784,0.00017732549,0.00025803348,0.00034022026,0.00018194316,0.00048287594,0.00017021144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003404446,0.00005725657,0.00013655466,0.000029279317,0.000005839529,0.000022235987,0.00001578549,0.00010054075,0.9982516,0.000012552937,0.0000075852304,0.0010202591],"study_design_scores_gemma":[0.000017677949,0.0013916539,0.0014787175,0.0000027678345,0.000024017329,0.00003830188,0.000010947427,0.0005831046,0.9962858,0.0000054633424,0.00015905226,0.0000024336211],"about_ca_topic_score_codex":0.0011594373,"about_ca_topic_score_gemma":0.0009450103,"teacher_disagreement_score":0.0011594373,"about_ca_system_score_codex":0.0002273085,"about_ca_system_score_gemma":0.0002851542,"threshold_uncertainty_score":0.0030891895},"labels":[],"label_agreement":null},{"id":"W32676954","doi":"10.1023/a:1013050330608","title":"Drug-Drug Interactions Arising From the Use of Liposomal Vincristine in Combination with Other Anticancer Drugs","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Drug; Anticancer drug; Pharmacology; Vincristine; Liposome; Medicine; Drug interaction; Approved drug; Chemistry; Chemotherapy; Internal medicine","score_opus":0.27231962334222193,"score_gpt":0.5117446603891239,"score_spread":0.239425037046902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W32676954","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815092,0.009938178,0.0027388749,0.00042747502,0.00008335402,0.00012217967,0.00012243113,0.00004351135,0.005014669],"genre_scores_gemma":[0.996846,0.0015612696,0.00067317614,0.00010780477,0.00004083337,0.000013186296,0.000055147742,0.000011450346,0.00069106644],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992853,0.000370325,0.00006242665,0.00005151021,0.0001723586,0.000058157962],"domain_scores_gemma":[0.9986265,0.000877655,0.00031859428,0.00004782586,0.000059749444,0.00006979105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094114954,0.00020957075,0.00044803513,0.00043892986,0.00038268513,0.00045944515,0.00016721817,0.00045374766,0.002394028],"category_scores_gemma":[0.0021381686,0.00014061171,0.00046529132,0.00041568352,0.00022312919,0.00029874267,0.000382256,0.0005805165,0.00037676393],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020207476,0.0009775392,0.070691675,0.0013933453,0.0014557258,0.017401142,0.0005687134,0.003058489,0.5981947,0.0017591671,0.0022249962,0.2820669],"study_design_scores_gemma":[0.00095930946,0.01845895,0.17019925,0.00021145261,0.0025073374,0.055059846,0.00058641186,0.013005495,0.67556816,0.0014818559,0.06186536,0.000096591684],"about_ca_topic_score_codex":0.00029276626,"about_ca_topic_score_gemma":0.00079005345,"teacher_disagreement_score":0.002394028,"about_ca_system_score_codex":0.0004091008,"about_ca_system_score_gemma":0.00020871029,"threshold_uncertainty_score":0.008008778},"labels":[],"label_agreement":null},{"id":"W328270376","doi":"10.1023/a:1019814713428","title":"Characterization of Asparagine Deamidation and Aspartate Isomerization in Recombinant Human Interleukin-11","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Deamidation; Recombinant DNA; Asparagine; Chemistry; Biochemistry; Isomerization; Aspartic acid; Stereochemistry; Amino acid; Enzyme","score_opus":0.1556430596101426,"score_gpt":0.43140086898556507,"score_spread":0.2757578093754225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W328270376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99377453,0.00052711205,0.004850522,0.000070998285,0.000018324006,0.000020014968,0.0002056795,0.000021522848,0.0005112807],"genre_scores_gemma":[0.99255294,0.0003856135,0.00409316,0.000047299032,0.0000068949853,0.00001939102,0.001168893,0.00003228456,0.0016935947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999793,0.000045507903,0.00003257052,0.00004090865,0.00005133659,0.00003671167],"domain_scores_gemma":[0.99968994,0.000095123614,0.00007631357,0.000046394223,0.000058619833,0.000033625318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003064306,0.00037199756,0.00022430213,0.00014733803,0.00013144639,0.00029895265,0.00022698363,0.00019653799,0.00057843706],"category_scores_gemma":[0.00046609974,0.00016523803,0.00031268082,0.00022476199,0.0001867117,0.00024078999,0.00015565415,0.00048212698,0.00031542758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017721878,0.000022610162,0.00026821042,0.00001560831,0.000005874109,0.00005324642,0.000019461124,0.000101969395,0.99820876,0.00006831944,0.000014061801,0.001044661],"study_design_scores_gemma":[0.000006280332,0.000049168288,0.0013551482,0.0000015180701,0.000006819433,0.00017018856,0.00001036245,0.00040130084,0.997471,0.000013562503,0.00051244063,0.0000023802718],"about_ca_topic_score_codex":0.0008420652,"about_ca_topic_score_gemma":0.00063443556,"teacher_disagreement_score":0.0008420652,"about_ca_system_score_codex":0.0003269921,"about_ca_system_score_gemma":0.000229856,"threshold_uncertainty_score":0.0023725033},"labels":[],"label_agreement":null},{"id":"W340700062","doi":"10.1023/a:1011062512712","title":"Rat and Rabbit Plasma Distribution of Free and Chylomicron-Associated BIRT 377, a Novel Small Molecule Antagonist of LFA-1-Mediated Cell Adhesion","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antagonist; Chemistry; Chylomicron; Cell adhesion molecule; Biophysics; Cell biology; Pharmacology; Biology; Biochemistry; Receptor; Lipoprotein; Cholesterol","score_opus":0.10214345507037709,"score_gpt":0.3939517162017471,"score_spread":0.29180826113137004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W340700062","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9780927,0.010147567,0.006019265,0.00028373822,0.00014188311,0.000041634707,0.00055138225,0.0001659152,0.0045559374],"genre_scores_gemma":[0.9886646,0.0036472792,0.0020061738,0.00013110098,0.00010812061,0.000047531463,0.0012207933,0.00004657746,0.004127822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997008,0.00004659826,0.000018790446,0.0000615651,0.000040007268,0.00013225869],"domain_scores_gemma":[0.9995989,0.00017011937,0.000052803407,0.000063141495,0.000028287843,0.00008677048],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046450231,0.0005137794,0.0003972048,0.000577636,0.00024607865,0.00049006025,0.00034958636,0.00049180555,0.002200445],"category_scores_gemma":[0.00064347463,0.00033154024,0.0004998663,0.000298978,0.00051703904,0.0008068183,0.00019765449,0.00091066235,0.00080973934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003675592,0.00011668697,0.00032325872,0.00012238759,0.000036299836,0.00023419296,0.000086525964,0.00009422656,0.98879504,0.00083763094,0.00022006394,0.005458218],"study_design_scores_gemma":[0.0002044772,0.003674256,0.011368792,0.000027258633,0.00021943332,0.0012700269,0.00009593466,0.0021697956,0.97575617,0.00047436942,0.0047169835,0.000022550772],"about_ca_topic_score_codex":0.0012106674,"about_ca_topic_score_gemma":0.001054792,"teacher_disagreement_score":0.002200445,"about_ca_system_score_codex":0.00049246626,"about_ca_system_score_gemma":0.0003533436,"threshold_uncertainty_score":0.0073612332},"labels":[],"label_agreement":null},{"id":"W4210312614","doi":"10.1007/s11095-022-03177-2","title":"Model-Based Assessment of the Contribution of Monocytes and Macrophages to the Pharmacokinetics of Monoclonal Antibodies","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Canadian Institutes of Health Research","keywords":"Monoclonal antibody; Monocyte; Macrophage; Antibody; Pharmacokinetics; Immunology; Chemistry; Endogeny; Pharmacology; Biology; In vitro; Biochemistry","score_opus":0.15592456969887136,"score_gpt":0.5014046276967534,"score_spread":0.34548005799788206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210312614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91422045,0.0015386855,0.08052203,0.0003047607,0.000045184646,0.00008574408,0.00045192256,0.00016404585,0.002667204],"genre_scores_gemma":[0.99407095,0.0005234237,0.0044890195,0.00004329177,0.000009491791,0.000048929054,0.00013540691,0.000013175233,0.00066628796],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99983585,0.00006265613,0.0000066730217,0.000033693337,0.00003430661,0.000026774102],"domain_scores_gemma":[0.9993742,0.00043645865,0.00006516311,0.00002107168,0.00007903497,0.000024116562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040244093,0.00041146803,0.00062564,0.00022962272,0.00017458595,0.00087257667,0.00040879785,0.000867025,0.00050971395],"category_scores_gemma":[0.0013463387,0.00023727665,0.0005573773,0.0001792307,0.00016457778,0.0003102651,0.00018918398,0.0004967102,0.00016211427],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010737041,0.00020765573,0.0059857434,0.00016679321,0.00014259589,0.00016775355,0.000045618563,0.9096794,0.06893753,0.0021240069,0.00057217875,0.010896997],"study_design_scores_gemma":[0.000036170557,0.00024496208,0.0012542281,0.0000038688995,0.000041657077,0.00005333583,0.000009707444,0.98935527,0.008125711,0.00051335606,0.0003474174,0.000014348641],"about_ca_topic_score_codex":0.009099881,"about_ca_topic_score_gemma":0.0037714732,"teacher_disagreement_score":0.009099881,"about_ca_system_score_codex":0.0008945415,"about_ca_system_score_gemma":0.0011850862,"threshold_uncertainty_score":0.018093824},"labels":[],"label_agreement":null},{"id":"W4223539746","doi":"10.1007/s11095-022-03255-5","title":"Analysis of Magneto-Hyperthermia Duration in Nano-sized Drug Delivery System to Solid Tumors Using Intravascular-Triggered Thermosensitive-Liposome","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Hyperthermia; Drug delivery; In vivo; Bioavailability; Liposome; Drug; Pharmacokinetics; Biomedical engineering; Hyperthermia therapy; Bolus (digestion); Pharmacology; Medicine; Materials science; Surgery; Nanotechnology; Internal medicine; Biology","score_opus":0.07594721622447874,"score_gpt":0.3849572415756921,"score_spread":0.30901002535121336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223539746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930172,0.0013454362,0.0045268484,0.00004272306,0.000025388441,0.0000215926,0.00014604272,0.000041234587,0.0008335854],"genre_scores_gemma":[0.99637645,0.00039805195,0.0019045848,0.00003229689,0.0000076618035,0.00003230623,0.00014534261,0.000014364924,0.0010888171],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999869,0.000013973445,0.000010018403,0.000043429733,0.00003659466,0.0000269551],"domain_scores_gemma":[0.99982774,0.000048557176,0.00005392626,0.000010674819,0.00003767709,0.00002149187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002504352,0.00020147946,0.00013985715,0.00014096883,0.00011547715,0.00019698676,0.00016740467,0.00022490238,0.0009041236],"category_scores_gemma":[0.00031494888,0.00011480741,0.0001650239,0.00014627735,0.00019844816,0.0003139,0.000095984265,0.00026830114,0.00015555815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001977252,0.000016303371,0.00017609118,0.000036071706,0.0000039079687,0.000012548398,0.000025243065,0.00009607744,0.9983047,0.000057640835,0.000023499746,0.0010501718],"study_design_scores_gemma":[0.000006092137,0.00017470888,0.0011185224,0.000001682057,0.000010799288,0.000018555173,0.000008707406,0.0010209414,0.9973115,0.0000109369585,0.00031397675,0.0000036860192],"about_ca_topic_score_codex":0.00047588037,"about_ca_topic_score_gemma":0.0005179642,"teacher_disagreement_score":0.0009041236,"about_ca_system_score_codex":0.00029151453,"about_ca_system_score_gemma":0.0001939476,"threshold_uncertainty_score":0.003024578},"labels":[],"label_agreement":null},{"id":"W4224223400","doi":"10.1007/s11095-022-03247-5","title":"A Novel Faster-Acting, Dry Powder-Based, Naloxone Intranasal Formulation for Opioid Overdose","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Opioid Use Disorder Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pharma Medica Research (Canada)","funders":"National Academy of Sciences of Ukraine","keywords":"(+)-Naloxone; Opioid overdose; Nasal administration; Pharmacology; Opioid; Medicine; Anesthesia; Chemistry; Internal medicine","score_opus":0.20540475877306605,"score_gpt":0.4831758732800295,"score_spread":0.27777111450696346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224223400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914893,0.00324403,0.0038500177,0.00011791889,0.000038463255,0.00023269761,0.00013362114,0.00007708775,0.000816997],"genre_scores_gemma":[0.99089277,0.0011949068,0.0060459455,0.0000765425,0.000021570682,0.00011359101,0.00014385593,0.000008852227,0.0015018937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998859,0.000017797602,0.0000067827586,0.000028644472,0.000048617087,0.000012176442],"domain_scores_gemma":[0.99994385,0.000007701566,0.000028747501,0.000003214896,0.0000066487764,0.0000098556675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015278975,0.0002303413,0.00026319566,0.00012889215,0.00008075074,0.00018474793,0.00027757196,0.00024172642,0.00143659],"category_scores_gemma":[0.00014280024,0.00009686753,0.00015905227,0.000058464786,0.00014871039,0.00024008208,0.00013504027,0.00037091062,0.00020315521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015927665,0.00081240735,0.00069370493,0.00038366255,0.000042586584,0.00018783813,0.000049266935,0.00021688266,0.9407053,0.000119043914,0.00024853036,0.05494789],"study_design_scores_gemma":[0.0066706054,0.13944575,0.067341626,0.00014750891,0.0004292877,0.005877157,0.00021011099,0.007887632,0.7455753,0.00012519861,0.026206557,0.00008327778],"about_ca_topic_score_codex":0.0004390767,"about_ca_topic_score_gemma":0.001264919,"teacher_disagreement_score":0.00143659,"about_ca_system_score_codex":0.00020413169,"about_ca_system_score_gemma":0.00020085377,"threshold_uncertainty_score":0.004805863},"labels":[],"label_agreement":null},{"id":"W4226397757","doi":"10.1007/s11095-022-03242-w","title":"Spray Dried Rugose Lipid Particle Platform for Respiratory Drug Delivery","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Spray drying; Raw material; Drug delivery; Particle (ecology); Chemical engineering; Chemistry; Pulmonary surfactant; Materials science; Particle size; Nanoparticle; Chromatography; Nanotechnology; Organic chemistry; Biochemistry; Physical chemistry","score_opus":0.2737846508614872,"score_gpt":0.47802390976155806,"score_spread":0.20423925890007089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226397757","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9625937,0.004942552,0.021908553,0.0002562501,0.00013228733,0.00014983144,0.00041577633,0.0003083188,0.00929281],"genre_scores_gemma":[0.9712512,0.0028622616,0.012119394,0.00019463598,0.000031467855,0.000076535,0.00036837047,0.000048554517,0.013047469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999174,0.000008810477,0.000003328248,0.000016234833,0.000035373192,0.000018783301],"domain_scores_gemma":[0.99997425,0.0000046277105,0.000006643395,0.0000027658316,0.0000065287077,0.0000051629877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012396538,0.00019613777,0.00022229254,0.00016341671,0.00010192118,0.00023467488,0.00015325901,0.0003782194,0.0020672677],"category_scores_gemma":[0.00010528882,0.000097638556,0.0002661138,0.00010447891,0.00013792898,0.00020302355,0.00022193698,0.00040678747,0.00084035826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003466949,0.0000120808745,0.000034452612,0.000048824346,0.000005361387,0.00007441197,0.000010001356,0.000110570036,0.99610233,0.00012838464,0.00008696049,0.0033518777],"study_design_scores_gemma":[0.000017208024,0.00065975793,0.0016738982,0.000014348624,0.000034554352,0.00024671192,0.00002953928,0.0016521923,0.98615116,0.00007848346,0.009429944,0.000012280896],"about_ca_topic_score_codex":0.00038087013,"about_ca_topic_score_gemma":0.000660046,"teacher_disagreement_score":0.0020672677,"about_ca_system_score_codex":0.0001306154,"about_ca_system_score_gemma":0.00017438048,"threshold_uncertainty_score":0.0069156885},"labels":[],"label_agreement":null},{"id":"W4244228243","doi":"10.1007/s11095-006-9077-3","title":"A Novel One-Step Drug Loading Procedure for Water-Soluble Amphiphilic Nanocarriers","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Nanocarriers; Amphiphile; Drug; Drug carrier; Chemistry; Drug delivery; Dosage form; Pharmaceutical technology; Pharmacology; Chromatography; Medicine; Organic chemistry; Copolymer; Polymer","score_opus":0.1232086412615128,"score_gpt":0.4032571763489392,"score_spread":0.2800485350874264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244228243","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38460833,0.005789582,0.594665,0.0008321338,0.00044321758,0.001670564,0.0007894753,0.0031642166,0.008037561],"genre_scores_gemma":[0.63478124,0.0041183843,0.34175387,0.00059590413,0.00017003961,0.0010775621,0.0008886485,0.0005228219,0.016091518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996612,0.000037830985,0.000038794293,0.00009595894,0.00012505383,0.00004117134],"domain_scores_gemma":[0.999741,0.00006877175,0.000071248476,0.000040355368,0.000049106835,0.00002948396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037322412,0.0008525683,0.0006631691,0.00059500034,0.0004997177,0.0003393358,0.00061615766,0.0006355752,0.0017708854],"category_scores_gemma":[0.00040396475,0.0004818901,0.00037262772,0.00030978658,0.0004143574,0.00096539804,0.00052123965,0.0012526494,0.0012588971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002898032,0.000036731566,0.000024221585,0.00008193978,0.000005039325,0.000039798684,0.000024774285,0.000054331107,0.9913544,0.0002123314,0.0001302852,0.0080071585],"study_design_scores_gemma":[0.000008390119,0.00006789308,0.0002038593,0.0000026545545,0.00000809915,0.00013022394,0.000003908035,0.0003767698,0.9966827,0.00003697191,0.002464545,0.00001388058],"about_ca_topic_score_codex":0.0005885434,"about_ca_topic_score_gemma":0.001153347,"teacher_disagreement_score":0.0017708854,"about_ca_system_score_codex":0.00037199788,"about_ca_system_score_gemma":0.0005669632,"threshold_uncertainty_score":0.005924225},"labels":[],"label_agreement":null},{"id":"W4282939104","doi":"10.1007/s11095-022-03285-z","title":"Pharmacokinetics and Pharmacodynamic Effect of a Blood-Brain Barrier-Crossing Fusion Protein Therapeutic for Alzheimer’s Disease in Rat and Dog","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada","keywords":"Blood–brain barrier; Pharmacokinetics; Pharmacodynamics; Pharmacology; Alzheimer's disease; Medicine; Neuroscience; Fusion protein; Disease; Central nervous system; Internal medicine; Chemistry; Biology; Biochemistry; Recombinant DNA","score_opus":0.09274935538154183,"score_gpt":0.4747862553927982,"score_spread":0.38203690001125634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282939104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961133,0.0010855533,0.0017793464,0.000119963195,0.000025621928,0.000037862384,0.00036322576,0.000092033275,0.00038310394],"genre_scores_gemma":[0.99575305,0.0009561278,0.0015703451,0.00007366558,0.000020435447,0.00006390918,0.0006676879,0.0000316073,0.00086316076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984276,0.000039123268,0.000008878847,0.000045454646,0.000033691198,0.000030139652],"domain_scores_gemma":[0.9998024,0.000033448134,0.00006743177,0.000031771964,0.000024358113,0.000040590756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003462343,0.00028132292,0.000493797,0.00026173526,0.00013985208,0.00042814232,0.00021010115,0.0003336482,0.00079534785],"category_scores_gemma":[0.00040602178,0.00017156861,0.0002489276,0.00018842466,0.00041433665,0.00047830687,0.000104969826,0.00060556154,0.00037771478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019903226,0.0014682361,0.008706415,0.00020824453,0.00015668251,0.00025191988,0.00029614652,0.0015393154,0.936527,0.00048002417,0.00153983,0.028923046],"study_design_scores_gemma":[0.0007461484,0.07267565,0.05337395,0.000033468317,0.0007222697,0.0030323982,0.0003873371,0.015820462,0.8327013,0.0005058356,0.019910716,0.00009051462],"about_ca_topic_score_codex":0.0010318938,"about_ca_topic_score_gemma":0.00072563475,"teacher_disagreement_score":0.0010318938,"about_ca_system_score_codex":0.00048921804,"about_ca_system_score_gemma":0.00030668045,"threshold_uncertainty_score":0.0035495758},"labels":[],"label_agreement":null},{"id":"W4286213443","doi":"10.1007/s11095-022-03341-8","title":"Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; University of British Columbia; McMaster University Medical Centre; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Dextran; Mannitol; Aerosolization; Chemistry; Excipient; Chromatography; Particle size; Freeze-drying; Aerosol; Spray drying; Materials science; Chemical engineering; Inhalation; Organic chemistry; Medicine","score_opus":0.1219017091269301,"score_gpt":0.42517973993385066,"score_spread":0.30327803080692056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286213443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973999,0.00018258505,0.0019273362,0.000034235953,0.000013646619,0.000011669934,0.000045059343,0.000052810996,0.00033263466],"genre_scores_gemma":[0.99731416,0.00013439538,0.0017089869,0.00002102939,0.0000043030313,0.000008681683,0.00004621511,0.00003079474,0.0007315621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998696,0.000016814518,0.000010129312,0.000037678197,0.00003456567,0.000031179297],"domain_scores_gemma":[0.9997756,0.00007569868,0.00007310664,0.000013233716,0.000025345724,0.000037056026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027304894,0.00016118267,0.00014133303,0.00013031707,0.0001319394,0.00033343007,0.00016156567,0.000221709,0.0011403293],"category_scores_gemma":[0.00045430442,0.00015136893,0.00010390889,0.00008880892,0.00020733578,0.0003321746,0.0001266933,0.00031652985,0.00029032992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013758976,0.000023407849,0.00011013238,0.000009223047,0.0000017302295,0.000009195724,0.000013627453,0.0001480685,0.9986318,0.000049802773,0.000022533663,0.0008427417],"study_design_scores_gemma":[0.000007884351,0.00018541203,0.0006940864,0.0000015134764,0.0000055041596,0.000020122437,0.000007740464,0.002499742,0.9963217,0.000009418576,0.00024300977,0.000004011903],"about_ca_topic_score_codex":0.0005052073,"about_ca_topic_score_gemma":0.0008297434,"teacher_disagreement_score":0.0011403293,"about_ca_system_score_codex":0.00029905897,"about_ca_system_score_gemma":0.00023818559,"threshold_uncertainty_score":0.0038147569},"labels":[],"label_agreement":null},{"id":"W4295923922","doi":"10.1007/s11095-022-03388-7","title":"In Vitro Regional Deposition of Nasal Sprays in an Idealized Nasal Inlet: Comparison with In Vivo Gamma Scintigraphy","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"In vivo; Deposition (geology); Nasal vestibule; Turbinates; Chemistry; Biomedical engineering; Expiration; Nasal cavity; Nose; Medicine; Anatomy; Respiratory system; Biology","score_opus":0.1678491146910184,"score_gpt":0.47292767474045905,"score_spread":0.3050785600494407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295923922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97683865,0.0024534715,0.018791966,0.000065689994,0.000054703985,0.00010196014,0.00012910116,0.000082799066,0.0014815963],"genre_scores_gemma":[0.9748847,0.0016162882,0.021455936,0.00004136196,0.00002090345,0.00007184386,0.00014624355,0.0000783509,0.0016843635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993611,0.00022869665,0.000037515794,0.00013964303,0.00012969521,0.000103276885],"domain_scores_gemma":[0.99937904,0.0003008056,0.00011434498,0.00009347735,0.000067630775,0.000044653658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013806801,0.0005963674,0.00068385387,0.00026831854,0.00026161925,0.0008169961,0.00050337444,0.0007212225,0.0007090508],"category_scores_gemma":[0.0010648074,0.00054647744,0.0004007851,0.00024096636,0.0008012803,0.00044753958,0.00039948168,0.0006206574,0.00024132895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030667646,0.00003555408,0.00016785711,0.000055947436,0.0000055121905,0.00006120066,0.000039903756,0.0006250436,0.9979353,0.00006151877,0.000012893141,0.0006926669],"study_design_scores_gemma":[0.000035862293,0.00077831774,0.0014617611,0.0000072841717,0.000039229762,0.00015376281,0.00007222184,0.0065236366,0.9903127,0.00002866421,0.00057481765,0.000011817087],"about_ca_topic_score_codex":0.002751165,"about_ca_topic_score_gemma":0.002163173,"teacher_disagreement_score":0.002751165,"about_ca_system_score_codex":0.0006257938,"about_ca_system_score_gemma":0.00068038574,"threshold_uncertainty_score":0.0073018074},"labels":[],"label_agreement":null},{"id":"W4308572249","doi":"10.1007/s11095-022-03421-9","title":"Using Filters to Estimate Regional Lung Deposition with Pressurized Metered Dose Inhalers","year":2022,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Deposition (geology); Metered-dose inhaler; Inhaler; Environmental science; Inhalation; Impaction; Biomedical engineering; Medicine; Anesthesia; Surgery; Asthma; Geology; Internal medicine","score_opus":0.34968834658681525,"score_gpt":0.5404790521685643,"score_spread":0.19079070558174904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308572249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6208967,0.0065229647,0.3665381,0.00020710412,0.00016782235,0.00033825607,0.0010766444,0.0010978604,0.0031545898],"genre_scores_gemma":[0.8795998,0.0020655142,0.11514776,0.00022672703,0.00006369554,0.00019379643,0.00046591825,0.00017678918,0.0020600515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877864,0.000316748,0.000049202656,0.00031498334,0.00048434926,0.000056095574],"domain_scores_gemma":[0.99876416,0.0006947959,0.00016804668,0.00010016618,0.00024475378,0.00002814726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015145333,0.0007198464,0.00082360266,0.0012839522,0.00032738075,0.001328877,0.0007358557,0.0017642179,0.0006280545],"category_scores_gemma":[0.0022424133,0.00053672434,0.0009108181,0.00063621515,0.00025923905,0.0010682844,0.00030449164,0.0004983869,0.0005310911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023277649,0.00027360237,0.13205732,0.0008013124,0.001081457,0.0003401064,0.00032598912,0.025638793,0.68804145,0.0005473924,0.0011899603,0.14737484],"study_design_scores_gemma":[0.00013516136,0.0018824277,0.18081543,0.00010715827,0.0012290075,0.0012739076,0.00024608272,0.29697463,0.51141745,0.000610868,0.005139701,0.00016812797],"about_ca_topic_score_codex":0.0073615904,"about_ca_topic_score_gemma":0.005716595,"teacher_disagreement_score":0.0073615904,"about_ca_system_score_codex":0.0005153924,"about_ca_system_score_gemma":0.000561582,"threshold_uncertainty_score":0.01463747},"labels":[],"label_agreement":null},{"id":"W4308834752","doi":"10.1007/s11095-022-03432-6","title":"Retraction Note: Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell Progression","year":2022,"lang":"en","type":"retraction","venue":"Pharmaceutical Research","topic":"Graphene and Nanomaterials Applications","field":"Engineering","cited_by":1,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chitosan; Chemistry; Cancer research; Nanoparticle; Cell; Cancer; Medicine; Nanotechnology; Materials science; Biochemistry; Internal medicine","score_opus":0.06182347319304988,"score_gpt":0.4101808908380219,"score_spread":0.348357417644972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308834752","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000460095,0.003897151,0.0004303921,0.13769905,0.85136145,0.00008220447,0.00034430943,0.00016390086,0.005561495],"genre_scores_gemma":[0.009825018,0.01273975,0.0023470307,0.21917403,0.5006102,0.0006361009,0.0009498166,0.00030803608,0.25341004],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99598026,0.00045956732,0.00069863716,0.0003169211,0.0020011882,0.00054340437],"domain_scores_gemma":[0.9884673,0.0048081484,0.0010160501,0.00049799157,0.004266962,0.00094352895],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0048414543,0.0021253412,0.0018333364,0.0015105968,0.0026122364,0.0024208608,0.0031023503,0.017263401,0.010396745],"category_scores_gemma":[0.0328286,0.0010581586,0.0016379186,0.0009272202,0.0020641554,0.0017198945,0.002079267,0.016818322,0.012786227],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032617798,0.000007013096,0.00002491248,0.000109232875,0.0000092967375,0.00038475977,0.000023245731,0.000019582432,0.00025276828,0.00032303145,0.9930386,0.005775132],"study_design_scores_gemma":[0.000049163795,0.000028716644,0.000508335,0.00018477376,0.000029563433,0.0006030224,0.00004570798,0.00014365267,0.0007186306,0.0003401264,0.99732375,0.00002456007],"about_ca_topic_score_codex":0.0062514,"about_ca_topic_score_gemma":0.006887665,"teacher_disagreement_score":0.9827366,"about_ca_system_score_codex":0.0046201497,"about_ca_system_score_gemma":0.005501789,"threshold_uncertainty_score":0.034780562},"labels":[{"model":"gemma","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"other","about_ca_system":false,"about_ca_topic":false,"confidence":"high"},{"model":"gpt","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"agree"},{"id":"W4315778102","doi":"10.1007/s11095-022-03465-x","title":"Mucopenetrating Janus Nanoparticles For Field-Coverage Oral Cancer Chemoprevention","year":2023,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Division of Materials Research; University of Michigan; Defense Threat Reduction Agency; Ohio State University; Fanconi Anemia Research Fund; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Chemistry; Cancer research; Medicine","score_opus":0.5696006231326929,"score_gpt":0.6464284923815071,"score_spread":0.07682786924881424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315778102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9197435,0.051083554,0.020457404,0.0005146876,0.0002791362,0.0002452022,0.00024090782,0.00049461494,0.0069410247],"genre_scores_gemma":[0.98087907,0.008491087,0.006393152,0.00014657652,0.000045173747,0.0000918761,0.000106816544,0.000028586584,0.003817698],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999931,0.000009996098,0.000004112905,0.000015720283,0.000025442525,0.000013694447],"domain_scores_gemma":[0.99995565,0.000006389076,0.000017143968,0.0000036552613,0.0000095255355,0.0000075963235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013196067,0.0002780156,0.00023496011,0.00027943944,0.00012265645,0.00028143643,0.0001911362,0.00030498963,0.0008943698],"category_scores_gemma":[0.000084287545,0.000117772324,0.00020477873,0.000109052475,0.00015453201,0.00020690229,0.00022317386,0.00028202115,0.0002704882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018690787,0.000085306136,0.00023462287,0.00034917123,0.000021127358,0.0000922864,0.000029237002,0.0005931865,0.9615425,0.00032640612,0.00046254494,0.036076784],"study_design_scores_gemma":[0.00006374323,0.0013378011,0.001870292,0.000044526776,0.000073902134,0.0004944172,0.000045713867,0.0043651043,0.9747216,0.00019741582,0.016767876,0.000017580132],"about_ca_topic_score_codex":0.0004186883,"about_ca_topic_score_gemma":0.0006951878,"teacher_disagreement_score":0.0008943698,"about_ca_system_score_codex":0.00023981508,"about_ca_system_score_gemma":0.00017885308,"threshold_uncertainty_score":0.0029919744},"labels":[],"label_agreement":null},{"id":"W4315778133","doi":"10.1007/s11095-022-03464-y","title":"Prediction of the Renal Organic Anion Transporter 1 (OAT1)- Mediated Drug Interactions for LY404039, the Active Metabolite of Pomaglumetad Methionil","year":2023,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Eli Lilly and Company","keywords":"Probenecid; Physiologically based pharmacokinetic modelling; Pharmacology; Chemistry; Pharmacokinetics; Organic anion transporter 1; Active metabolite; Prodrug; Renal physiology; Renal function; Metabolite; Transporter; Biochemistry; Medicine","score_opus":0.2071999022809482,"score_gpt":0.4489336531871499,"score_spread":0.2417337509062017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315778133","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98688626,0.0027339265,0.0036118268,0.00054785924,0.000054174143,0.00006317618,0.0043244893,0.00035380194,0.0014245836],"genre_scores_gemma":[0.99227095,0.00032443283,0.0024417203,0.00015435935,0.00002713597,0.000015630056,0.004300005,0.000033349494,0.0004324059],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946755,0.00014115383,0.000046826673,0.00012854139,0.00016008437,0.00005586718],"domain_scores_gemma":[0.9989272,0.0005029864,0.00031091817,0.00003111755,0.00011944718,0.0001083188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072686456,0.0006899544,0.00091126736,0.0009764596,0.00031976373,0.0008243879,0.00038051736,0.0008014205,0.0028450342],"category_scores_gemma":[0.0016217553,0.00016310536,0.0015248996,0.00058765104,0.00014491819,0.00030649867,0.0002934397,0.0006147956,0.0009896174],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016444664,0.0011807018,0.67625046,0.0009533581,0.003425995,0.005678181,0.000120778364,0.037921347,0.13533029,0.0011190111,0.010727472,0.11084781],"study_design_scores_gemma":[0.0020872056,0.0053779096,0.37249368,0.00015889492,0.005269053,0.012298653,0.00026448112,0.5019224,0.07909797,0.0021517077,0.018697461,0.00018059996],"about_ca_topic_score_codex":0.0025093358,"about_ca_topic_score_gemma":0.0031796696,"teacher_disagreement_score":0.0028450342,"about_ca_system_score_codex":0.0006122814,"about_ca_system_score_gemma":0.00066046475,"threshold_uncertainty_score":0.00951761},"labels":[],"label_agreement":null},{"id":"W4361293623","doi":"10.1007/s11095-023-03492-2","title":"Design Considerations for Intratracheal Delivery Devices to Achieve Proof-of-Concept Dry Powder Biopharmaceutical Delivery in Mice","year":2023,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; University of British Columbia; McMaster University Medical Centre; St. Joseph's Hospital; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Materials science; Aerosolization; Biomedical engineering; In vivo; Mannitol; Composite material; Inhalation; Chemistry; Medicine; Anesthesia","score_opus":0.3327434375892607,"score_gpt":0.4920212126717326,"score_spread":0.15927777508247187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361293623","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23162231,0.008434275,0.74247366,0.002521347,0.00092863425,0.002958365,0.0010236592,0.0010589928,0.008978714],"genre_scores_gemma":[0.48881716,0.0053845565,0.48864454,0.0011069623,0.00022361222,0.0030853394,0.00090936094,0.00025836224,0.011570112],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944323,0.00010586991,0.000053789772,0.00009809031,0.00023654908,0.00006255995],"domain_scores_gemma":[0.9994068,0.00023031917,0.00013830152,0.00005064167,0.00013756304,0.00003633157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017637056,0.00070716674,0.0004502836,0.00044750888,0.0003609634,0.0011487773,0.00072710606,0.0014016217,0.0016127871],"category_scores_gemma":[0.0013374768,0.00054537307,0.0006201288,0.000140095,0.00031629484,0.00089534465,0.000314518,0.0007416925,0.0011931605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016450632,0.00008629496,0.00016900293,0.00028289173,0.000015554475,0.00009112877,0.000038099002,0.0009704462,0.98628867,0.0016230278,0.0005901128,0.009680434],"study_design_scores_gemma":[0.00007534874,0.0011517444,0.0008368833,0.000046896595,0.000066357876,0.0003144259,0.000048964193,0.007341454,0.9670931,0.00044865123,0.02254788,0.000028232045],"about_ca_topic_score_codex":0.0002595643,"about_ca_topic_score_gemma":0.000433597,"teacher_disagreement_score":0.0017637056,"about_ca_system_score_codex":0.00046582567,"about_ca_system_score_gemma":0.0005256126,"threshold_uncertainty_score":0.009327471},"labels":[],"label_agreement":null},{"id":"W4366496023","doi":"10.1007/s11095-023-03472-6","title":"Central and peripheral lung deposition of fluticasone propionate dry powder inhaler formulations in humans characterized by population pharmacokinetics","year":2023,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"U.S. Food and Drug Administration; Hamilton Health Sciences Foundation","keywords":"Fluticasone propionate; Pharmacokinetics; Bioequivalence; Mucociliary clearance; Dry-powder inhaler; Population; Pharmacology; Absorption (acoustics); Bioavailability; Medicine; Chemistry; Inhalation; Inhaler; Lung; Anesthesia; Internal medicine; Asthma; Materials science","score_opus":0.0938101301099307,"score_gpt":0.44367654673315643,"score_spread":0.3498664166232257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366496023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950781,0.0016821102,0.002084993,0.000047328238,0.00001065282,0.000039515984,0.00020803662,0.00004116025,0.0008081359],"genre_scores_gemma":[0.998198,0.00041096788,0.00060706853,0.000056881774,0.0000141512455,0.000026539406,0.0001742454,0.000015623094,0.0004965729],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999686,0.00008183761,0.00001257883,0.00010555323,0.00007092411,0.000043038697],"domain_scores_gemma":[0.9996338,0.00012323924,0.00011249788,0.000045277473,0.000043110886,0.000042030613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046790595,0.00024859555,0.00040135725,0.00034123063,0.00018541748,0.0006141441,0.00014494958,0.00047230598,0.0012953818],"category_scores_gemma":[0.0007374127,0.00033260902,0.00026791746,0.00018247149,0.00044611967,0.00032702385,0.00015682122,0.00040489505,0.0003478258],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0305486,0.00063889934,0.15169819,0.00032742324,0.00036192161,0.0018190588,0.00069855957,0.0016097504,0.7454786,0.00069969834,0.0009665861,0.06515259],"study_design_scores_gemma":[0.00028164245,0.0065993816,0.8903887,0.00001994543,0.00029211372,0.005529645,0.00048793436,0.0067791347,0.08759673,0.00047671952,0.0015021618,0.000045885932],"about_ca_topic_score_codex":0.0016901892,"about_ca_topic_score_gemma":0.0011584089,"teacher_disagreement_score":0.0016901892,"about_ca_system_score_codex":0.00027902066,"about_ca_system_score_gemma":0.0003622154,"threshold_uncertainty_score":0.004333496},"labels":[],"label_agreement":null},{"id":"W4367595612","doi":"10.1007/s11095-023-03528-7","title":"Analysis of the Adsorbed Vaccine Formulations Using Water Proton Nuclear Magnetic Resonance—Comparison with Optical Analytics","year":2023,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"Sanofi","keywords":"Adjuvant; Materials science; Adsorption; Laser; Chemistry; Analytical Chemistry (journal); Chromatography; Optics; Medicine; Immunology; Organic chemistry","score_opus":0.16023530380193282,"score_gpt":0.4599565278683611,"score_spread":0.2997212240664283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367595612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786632,0.001639179,0.017271893,0.00014348763,0.000062266015,0.000073224,0.0002863739,0.00010681975,0.0017535421],"genre_scores_gemma":[0.98244596,0.0011954358,0.012361627,0.00016616343,0.000023157687,0.00007277102,0.00053602236,0.00007287241,0.0031260066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99964726,0.000071395705,0.000019147645,0.00006347795,0.0001410039,0.000057717305],"domain_scores_gemma":[0.9996284,0.00013241179,0.00005681897,0.000028485816,0.00012438225,0.00002946341],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055210595,0.00044311222,0.00019335434,0.00034985575,0.00023255264,0.00047170106,0.0002673319,0.0003497499,0.001083805],"category_scores_gemma":[0.00084406673,0.00016528484,0.00023503295,0.00025133532,0.00039288434,0.0004959151,0.00024445157,0.00061503326,0.00029833967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097255695,0.000022118516,0.00027109776,0.00003367037,0.000006764371,0.000011663868,0.000031196632,0.00007012424,0.99777454,0.000042490374,0.000022360577,0.0016166565],"study_design_scores_gemma":[0.000003841735,0.00025450456,0.001993892,0.000004373601,0.000017280961,0.000043201762,0.000048043978,0.00097064226,0.99601114,0.000025908315,0.00062205194,0.0000051141888],"about_ca_topic_score_codex":0.0013668758,"about_ca_topic_score_gemma":0.0012290693,"teacher_disagreement_score":0.0013668758,"about_ca_system_score_codex":0.00021650236,"about_ca_system_score_gemma":0.0003070825,"threshold_uncertainty_score":0.0036256313},"labels":[],"label_agreement":null},{"id":"W4389130803","doi":"10.1007/s11095-023-03635-5","title":"Professor David E. Smith: A Fearless Scientist and Devoted Mentor","year":2023,"lang":"en","type":"editorial","venue":"Pharmaceutical Research","topic":"Academic Writing and Publishing","field":"Arts and Humanities","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"University at Buffalo","keywords":"Philosophy; Epistemology","score_opus":0.29884240783146016,"score_gpt":0.49934828430144185,"score_spread":0.2005058764699817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389130803","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00002569992,0.0038235986,0.00011962035,0.0583925,0.9343413,0.000023882216,0.000027974875,0.000054238153,0.0031910916],"genre_scores_gemma":[0.0009340282,0.0069367806,0.0002774826,0.048917055,0.8889413,0.000046593243,0.00004845781,0.00012453501,0.053773805],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9912282,0.0014405355,0.0008340965,0.0007955642,0.0052685263,0.00043294235],"domain_scores_gemma":[0.9456207,0.014994417,0.0021343068,0.0014600295,0.027441286,0.008349263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01071901,0.0026842554,0.002479935,0.003405568,0.0036818206,0.010214067,0.0034939675,0.012758352,0.021782259],"category_scores_gemma":[0.050324332,0.0010955657,0.0017369642,0.0014137924,0.002279866,0.004579078,0.0014217718,0.01788533,0.025084814],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009472582,0.0000033369965,0.000009106357,0.000057458907,0.000003875006,0.00004478067,0.0000076699225,0.000008194599,0.000024139445,0.00019571876,0.9976311,0.0020052204],"study_design_scores_gemma":[0.0000247142,0.000012941629,0.000094482246,0.00023910972,0.0000147987175,0.00018015518,0.000043836408,0.00006935586,0.00008875083,0.0006632278,0.9985561,0.000012442105],"about_ca_topic_score_codex":0.002404178,"about_ca_topic_score_gemma":0.008066443,"teacher_disagreement_score":0.021782259,"about_ca_system_score_codex":0.0034839376,"about_ca_system_score_gemma":0.0061973557,"threshold_uncertainty_score":0.07286888},"labels":[],"label_agreement":null},{"id":"W4389941780","doi":"10.1007/s11095-023-03642-6","title":"Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing","year":2023,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Mineral Processing and Grinding","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Suspension (topology); Particle size; Adjuvant; Mixing (physics); Materials science; Critical quality attributes; Particle (ecology); Continuous flow; Process engineering; Chemical engineering; Chemistry; Mathematics; Medicine; Physics; Engineering","score_opus":0.12094030345623007,"score_gpt":0.42759474350111093,"score_spread":0.30665444004488085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389941780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.723219,0.0084435325,0.24311993,0.000920486,0.00028675172,0.00027952326,0.00024180215,0.0009815526,0.022507466],"genre_scores_gemma":[0.9095503,0.0030555443,0.076252215,0.00027335456,0.000041458377,0.000102462815,0.00010859127,0.000062573185,0.010553467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973935,0.000050230457,0.000010579644,0.000055188837,0.00010116067,0.000043396318],"domain_scores_gemma":[0.99966514,0.00013241514,0.000084976906,0.00003705649,0.000057328783,0.000023086883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044680788,0.0004328792,0.00019235951,0.0003851804,0.00023516921,0.00056061347,0.00028301263,0.00067528174,0.0016992828],"category_scores_gemma":[0.0005473347,0.0003158341,0.0002869148,0.0003054619,0.00039005242,0.00065922335,0.0004863071,0.0006179679,0.0007192889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004383705,0.000011737721,0.00009318537,0.000057201403,0.000002337215,0.00006323803,0.000024745295,0.00017313636,0.99398744,0.00063718675,0.00005567283,0.0048501967],"study_design_scores_gemma":[0.0000030960844,0.0001071928,0.00020896162,0.0000041270637,0.0000036990384,0.000116923875,0.000014430441,0.00069707533,0.995808,0.00008553444,0.0029478106,0.000003104576],"about_ca_topic_score_codex":0.00025500593,"about_ca_topic_score_gemma":0.0004533099,"teacher_disagreement_score":0.0016992828,"about_ca_system_score_codex":0.00035885122,"about_ca_system_score_gemma":0.00026457614,"threshold_uncertainty_score":0.005684614},"labels":[],"label_agreement":null},{"id":"W4395013187","doi":"10.1007/s11095-024-03698-y","title":"Assessment of Tunable Resistive Pulse Sensing (TRPS) Technology for Particle Size Distribution in Vaccine Formulations – A Comparative Study with Dynamic Light Scattering","year":2024,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Dynamic light scattering; Particle size; Particle-size distribution; Materials science; Sizing; Particle (ecology); Light scattering; Range (aeronautics); Coulter counter; Scattering; Characterization (materials science); Resistive touchscreen; Biological system; Nanotechnology; Nanoparticle; Chemistry; Optics; Computer science; Physics","score_opus":0.07385703505221163,"score_gpt":0.5075695551176995,"score_spread":0.4337125200654879,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395013187","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9455012,0.0019019878,0.049768344,0.00018199632,0.00009477398,0.000120809695,0.00018582375,0.0002564399,0.0019885553],"genre_scores_gemma":[0.97530884,0.0010729316,0.021421554,0.00010420524,0.00003078272,0.00007594602,0.000106796404,0.000042387277,0.001836482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991704,0.0002069766,0.000043655924,0.00020549384,0.00029586628,0.0000775058],"domain_scores_gemma":[0.99905974,0.00050934084,0.0001609852,0.000072153205,0.00016096263,0.00003674928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012688845,0.0004164937,0.00027101662,0.00028860892,0.00017516372,0.00056307367,0.00047526884,0.0006119375,0.0009835823],"category_scores_gemma":[0.001500587,0.00023153536,0.00042631026,0.00026508013,0.00049483596,0.0007474216,0.0003373615,0.000714272,0.00035241124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068951245,0.000025562887,0.00010543541,0.00003717371,0.0000048501765,0.000017578886,0.000049795755,0.000119451295,0.9969382,0.00007811121,0.000020076808,0.0025347767],"study_design_scores_gemma":[0.0000033926228,0.0003029335,0.0005801136,0.0000030848175,0.000012401772,0.000058176047,0.00003741042,0.0026560363,0.995943,0.00003309269,0.00036266548,0.000007647655],"about_ca_topic_score_codex":0.00028995844,"about_ca_topic_score_gemma":0.0002960934,"teacher_disagreement_score":0.0012688845,"about_ca_system_score_codex":0.00031666146,"about_ca_system_score_gemma":0.0002184838,"threshold_uncertainty_score":0.0067105293},"labels":[],"label_agreement":null},{"id":"W4401242507","doi":"10.1007/s11095-024-03742-x","title":"Machine Learning Prediction of On/Off Target-driven Clinical Adverse Events","year":2024,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centennial College","funders":"","keywords":"Adverse effect; Computer science; Artificial intelligence; Medicine; Machine learning; Pharmacology","score_opus":0.3271439234270387,"score_gpt":0.5617736059562758,"score_spread":0.2346296825292371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401242507","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96280324,0.0016846624,0.027009178,0.0008802021,0.00016297746,0.00009487534,0.003958668,0.00039371641,0.003012498],"genre_scores_gemma":[0.9947659,0.0001933298,0.0022944976,0.00009577614,0.000059321992,0.000017032462,0.0019128995,0.0000115002795,0.0006497317],"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99922705,0.00024903947,0.00007006931,0.00018353197,0.00015875131,0.00011150391],"domain_scores_gemma":[0.9926112,0.0055691293,0.000807764,0.0002726721,0.00048046547,0.00025882263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002141179,0.00047740765,0.0008172106,0.0009921172,0.00019632542,0.00088747975,0.00057920226,0.0006361609,0.0019494828],"category_scores_gemma":[0.008147967,0.00013892805,0.0008127475,0.00047827285,0.00022517146,0.00042358466,0.0003441315,0.0012209556,0.00042987938],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0063957954,0.0018465823,0.48076418,0.0003564654,0.00078483217,0.00094764534,0.00007402498,0.24352738,0.006137794,0.0031181008,0.008013071,0.2480341],"study_design_scores_gemma":[0.00014646261,0.0008583763,0.06097794,0.00003929991,0.00020333214,0.0004270921,0.00003361384,0.92790455,0.0032370926,0.00505079,0.001097432,0.000024098037],"about_ca_topic_score_codex":0.001763391,"about_ca_topic_score_gemma":0.0021972165,"teacher_disagreement_score":0.002141179,"about_ca_system_score_codex":0.0003914637,"about_ca_system_score_gemma":0.0006478933,"threshold_uncertainty_score":0.01132375},"labels":[],"label_agreement":null},{"id":"W4407960676","doi":"10.1007/s11095-025-03823-5","title":"Regulatory and Industry Perspective on the Model Master File Framework for Locally Acting Drug Products","year":2025,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Safe Handling of Antineoplastic Drugs","field":"Health Professions","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Perspective (graphical); Pharmaceutical industry; Drug; Computer science; Pharmaceutical technology; Chemistry; Business; Pharmacology; Process management; Risk analysis (engineering); Computational biology; Biochemical engineering; Medicine; Engineering; Biology; Chromatography","score_opus":0.385501946504641,"score_gpt":0.5887874360315967,"score_spread":0.2032854895269557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407960676","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0053687524,0.0016472583,0.59910136,0.084053665,0.002026084,0.0009844215,0.0063952203,0.005022189,0.29540116],"genre_scores_gemma":[0.22583039,0.0036871647,0.59707844,0.02106271,0.002267339,0.0022448283,0.0073022926,0.0033071,0.13721964],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.98470193,0.006443682,0.0005707923,0.0016210721,0.0056000687,0.0010623344],"domain_scores_gemma":[0.9713306,0.014543226,0.0013320267,0.0058512613,0.005874978,0.0010678221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02302248,0.0013080536,0.0011289663,0.0029815375,0.0020586075,0.015833328,0.0073592495,0.009579528,0.095094636],"category_scores_gemma":[0.039692998,0.0010864374,0.0029769186,0.002682419,0.006421385,0.013465445,0.0050157574,0.0079516815,0.019843586],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003535171,0.000038568953,0.0001458445,0.00011442119,0.0000141388555,0.00007232321,0.00013271837,0.005185026,0.000301512,0.9509184,0.03007556,0.012966238],"study_design_scores_gemma":[0.0000872272,0.00013401858,0.0003445891,0.00067098567,0.000050937477,0.00015797003,0.00033164182,0.02256891,0.0012576905,0.50577545,0.46852967,0.00009077739],"about_ca_topic_score_codex":0.01704404,"about_ca_topic_score_gemma":0.0143879475,"teacher_disagreement_score":0.095094636,"about_ca_system_score_codex":0.007229888,"about_ca_system_score_gemma":0.017514685,"threshold_uncertainty_score":0.31812322},"labels":[],"label_agreement":null},{"id":"W4409525689","doi":"10.1007/s11095-025-03858-8","title":"Learning Chemotherapy Drug Action via Universal Physics-Informed Neural Networks","year":2025,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Action (physics); Drug; Pharmacology; Medicine; Computer science; Medical physics; Neuroscience; Physics; Psychology; Quantum mechanics","score_opus":0.14966742501368466,"score_gpt":0.5109897031864745,"score_spread":0.36132227817278983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409525689","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.107246466,0.0019808456,0.87779844,0.0019677954,0.00018925613,0.00009342724,0.00031865525,0.0010595516,0.009345607],"genre_scores_gemma":[0.94663435,0.000552535,0.047717933,0.00052741595,0.00012897313,0.0001334207,0.00024403854,0.00005980491,0.0040015695],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9997893,0.000060348124,0.0000108407685,0.000060286344,0.00004641069,0.000032821536],"domain_scores_gemma":[0.9989166,0.00076228805,0.00012231419,0.000058607566,0.00009750862,0.000042667118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068706926,0.0006014569,0.0010843477,0.0008504498,0.00039645063,0.0007294109,0.0014616387,0.0015731697,0.0023109347],"category_scores_gemma":[0.0032419192,0.00063795777,0.0007434265,0.00059212727,0.0010293876,0.0013789264,0.0010760147,0.0012910881,0.00032449834],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043795306,0.00003718781,0.00042741923,0.00004785636,0.000030904397,0.000027888156,0.00001245347,0.96525675,0.00051130244,0.010253567,0.0007055744,0.022645362],"study_design_scores_gemma":[0.000004511809,0.0000058739956,0.000040136998,0.000002920523,0.000003475491,0.0000038849153,0.0000011145986,0.99403447,0.00009034951,0.0057283845,0.00008313233,0.0000016668943],"about_ca_topic_score_codex":0.006596283,"about_ca_topic_score_gemma":0.008530479,"teacher_disagreement_score":0.006596283,"about_ca_system_score_codex":0.0011828116,"about_ca_system_score_gemma":0.0012662738,"threshold_uncertainty_score":0.013115823},"labels":[],"label_agreement":null},{"id":"W4409872774","doi":"10.1007/s11095-025-03860-0","title":"An In Vitro Dissolution Method for Inhaled Drugs Depositing in the Tracheobronchial Lung Region","year":2025,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Dissolution; Lung; In vitro; Pharmacology; Pharmaceutical technology; Drug; Inhalation; Chemistry; Medicine; Anesthesia; Chromatography; Internal medicine; Biochemistry","score_opus":0.13245103672821057,"score_gpt":0.5389695446723637,"score_spread":0.4065185079441531,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409872774","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.62592787,0.014425767,0.34190962,0.0009476349,0.0004947807,0.0011402764,0.0013239345,0.0005945488,0.0132356305],"genre_scores_gemma":[0.70936537,0.009852117,0.25981086,0.00024997423,0.0001658633,0.0005943845,0.0010517928,0.00017533232,0.018734224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995034,0.00012115715,0.00004870929,0.00010184957,0.00018038406,0.00004447925],"domain_scores_gemma":[0.9996044,0.00013904493,0.00008675755,0.000054537148,0.00008572275,0.000029588145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006452494,0.00054159097,0.00040979026,0.0005028119,0.0004632807,0.00033286153,0.00041979132,0.00047450635,0.0013983767],"category_scores_gemma":[0.0004860279,0.0003089127,0.00055022415,0.00025262882,0.0003383255,0.0003625956,0.00037494462,0.0007874502,0.0008134216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007151331,0.000026478097,0.00018003098,0.000113266164,0.000009380451,0.00011157981,0.000037671314,0.000051048584,0.9945121,0.00007927322,0.000061879866,0.0047459085],"study_design_scores_gemma":[0.000020675529,0.00044275675,0.0027417191,0.000015317857,0.00007343447,0.00078918785,0.000049027567,0.0016058894,0.9894968,0.00003390316,0.004713638,0.000017475148],"about_ca_topic_score_codex":0.0021545342,"about_ca_topic_score_gemma":0.004627458,"teacher_disagreement_score":0.0021545342,"about_ca_system_score_codex":0.00022301839,"about_ca_system_score_gemma":0.0005047012,"threshold_uncertainty_score":0.0046780705},"labels":[],"label_agreement":null},{"id":"W4411368853","doi":"10.1007/s11095-025-03875-7","title":"A New Analytical LC–MS/MS Method for Determination of Eight Standard Nitrosamines (NDMA, NMBA, NDEA, NEIPA, NDIPA, NMPA, NDPA, NDBA) in a Commercial Small Molecule Drug Product Capsules and its Active Pharmaeceutical Ingredient for Treatment of Fabry: A Rare Disease","year":2025,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SGS (Canada)","funders":"","keywords":"Active ingredient; Chromatography; Chemistry; Small molecule; Pharmacology; Medicine; Biochemistry","score_opus":0.1645648962085731,"score_gpt":0.5150118721846387,"score_spread":0.35044697597606567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411368853","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2705653,0.020934964,0.6711094,0.0018904286,0.0017378271,0.0022139258,0.0037006724,0.009279405,0.018568136],"genre_scores_gemma":[0.41705462,0.005675701,0.5429748,0.0043625417,0.0003228461,0.002372995,0.0039971266,0.00028835534,0.022951057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985487,0.00017427372,0.0000938393,0.0004710873,0.0006396128,0.0000725594],"domain_scores_gemma":[0.99922884,0.00015378163,0.00012583278,0.00007064311,0.0003173226,0.000103581595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011079763,0.0014261187,0.00064543023,0.0021242313,0.0009149972,0.00047166215,0.0011565187,0.0019455955,0.0018963189],"category_scores_gemma":[0.0013044793,0.0007093154,0.00060519314,0.00061239436,0.00076708075,0.0011212581,0.0008804833,0.0015353361,0.0016288077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022458908,0.00024237944,0.0015175306,0.00027783375,0.00010153528,0.0001711516,0.00005530131,0.00017626115,0.9608687,0.0004416523,0.0010224053,0.03490068],"study_design_scores_gemma":[0.00014390486,0.0010219391,0.006880429,0.00007816641,0.00023538794,0.0049977577,0.00008244751,0.008916912,0.95272386,0.00081364316,0.023933074,0.00017242518],"about_ca_topic_score_codex":0.0010264125,"about_ca_topic_score_gemma":0.0028265344,"teacher_disagreement_score":0.0021242313,"about_ca_system_score_codex":0.0006187432,"about_ca_system_score_gemma":0.0016754111,"threshold_uncertainty_score":0.0063438416},"labels":[],"label_agreement":null},{"id":"W4411862316","doi":"10.1007/s11095-025-03883-7","title":"Evaluation of the Combination of L‑leucine to Chitosan on Sustained Release of Inhalable Heparin Sodium Microparticles","year":2025,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chitosan; Heparin; Chemistry; Pharmaceutical technology; Microparticle; Pharmacology; Sodium; Liberation; Chromatography; Medicine; Biochemistry; In vitro; Chemical engineering; Organic chemistry","score_opus":0.1822115518726578,"score_gpt":0.5070736649908609,"score_spread":0.3248621131182031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411862316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99710125,0.0017072703,0.00060682296,0.000028618359,0.000045547506,0.000038314738,0.00004375668,0.000018373641,0.0004100697],"genre_scores_gemma":[0.9965109,0.00093622046,0.0014423343,0.000028218263,0.000019854273,0.000024434523,0.000044739056,0.000007949799,0.0009853605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997886,0.000041048923,0.000021974418,0.000039240196,0.00007049903,0.00003861327],"domain_scores_gemma":[0.99983644,0.00003707408,0.000042666634,0.000009379018,0.000042530377,0.00003187767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002242566,0.00028956917,0.00035515628,0.00020089571,0.00014497183,0.00023890656,0.00023266887,0.00033241056,0.0005962725],"category_scores_gemma":[0.00033634913,0.00012157561,0.00037540798,0.00016394704,0.00016954505,0.00024580126,0.00016467982,0.00026888016,0.00013112229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009940342,0.00012541167,0.00016013879,0.00017906033,0.000028142687,0.00008303304,0.000022173577,0.00016782303,0.99409604,0.000018022194,0.000033903012,0.0040921876],"study_design_scores_gemma":[0.000056366676,0.0037082904,0.0016799368,0.000008204405,0.00008792113,0.00009120423,0.000021171438,0.0007633834,0.99268264,0.0000037495931,0.00088460965,0.000012668099],"about_ca_topic_score_codex":0.0010008652,"about_ca_topic_score_gemma":0.0014053783,"teacher_disagreement_score":0.0010008652,"about_ca_system_score_codex":0.00018047831,"about_ca_system_score_gemma":0.00020981928,"threshold_uncertainty_score":0.0019947886},"labels":[],"label_agreement":null},{"id":"W4414869167","doi":"10.1007/s11095-025-03920-5","title":"Metabolic Insights into Drug Absorption: Unveiling Piperine's Transformative Bioenhancing Potential","year":2025,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Piperaceae Chemical and Biological Studies","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Piperine; Bioavailability; Drug; Pharmacokinetics; Efflux; Prodrug; Drug metabolism; Intestinal permeability","score_opus":0.2138467517681159,"score_gpt":0.5362313292573191,"score_spread":0.3223845774892032,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414869167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9160509,0.023311876,0.038309433,0.0032504643,0.00023759753,0.00011398197,0.00075404684,0.00028913782,0.017682604],"genre_scores_gemma":[0.9843758,0.0061219833,0.0067353793,0.00027893315,0.000057438818,0.0000142402,0.00015962351,0.000023377892,0.00223323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999665,0.000007356274,0.0000015217579,0.00000894125,0.000006525949,0.000009065059],"domain_scores_gemma":[0.99992394,0.00002351556,0.000023244698,0.000007784767,0.00001019121,0.000011372206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015524002,0.0004623682,0.00017796864,0.0001661164,0.00013431432,0.00031963573,0.00021518298,0.0003828185,0.002977107],"category_scores_gemma":[0.00019537921,0.00013360791,0.00026058638,0.00016193259,0.00024125441,0.0009909458,0.0002240839,0.0007346023,0.0002654395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057621964,0.00009309363,0.00053699536,0.0003823535,0.000019899608,0.00031704715,0.00008362649,0.0006113302,0.96339756,0.0029165226,0.00018274503,0.03088269],"study_design_scores_gemma":[0.000056213616,0.0019798763,0.005735465,0.000056683577,0.00007803416,0.00071615,0.00015779729,0.004526028,0.9707343,0.0029596514,0.012971834,0.000028032802],"about_ca_topic_score_codex":0.00028816983,"about_ca_topic_score_gemma":0.00047213113,"teacher_disagreement_score":0.002977107,"about_ca_system_score_codex":0.00020218437,"about_ca_system_score_gemma":0.00020806037,"threshold_uncertainty_score":0.0099594},"labels":[],"label_agreement":null},{"id":"W4417275037","doi":"10.1007/s11095-025-03982-5","title":"How Breathing Interruptions Influence pMDI Aerosol Delivery: A CFD Study in a Realistic Airway","year":2025,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Airway; Breathing; Aerosol; Deposition (geology); Respiratory physiology; Lung disease","score_opus":0.18189074724344076,"score_gpt":0.5042203058423192,"score_spread":0.32232955859887846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417275037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98378366,0.0005649913,0.010017638,0.00053037796,0.00015478327,0.00010745507,0.00030053942,0.00012724355,0.0044132774],"genre_scores_gemma":[0.99665916,0.00019965645,0.0017918377,0.00007155528,0.000031832053,0.000026832873,0.00011192377,0.00002414239,0.001083057],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99961334,0.00007719094,0.000023187404,0.00008327838,0.00011046164,0.000092478556],"domain_scores_gemma":[0.9984829,0.0012042255,0.000068754875,0.00006568681,0.000105059255,0.00007337984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046494708,0.0003297831,0.00053660286,0.00024333074,0.00046961103,0.0010443779,0.000586298,0.0018327667,0.0014561428],"category_scores_gemma":[0.002597012,0.00033488494,0.00057452545,0.00017030915,0.00050892093,0.00063562306,0.0005291969,0.00068747794,0.0003164351],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001738706,0.001239199,0.016577832,0.00060520315,0.00010749542,0.002816979,0.00088794035,0.70159864,0.24260724,0.0025586796,0.0027738495,0.026488287],"study_design_scores_gemma":[0.00016631058,0.0013366146,0.011701467,0.00003642369,0.000079038786,0.0004679306,0.00028294674,0.95355356,0.029571233,0.0004402329,0.002283614,0.000080638274],"about_ca_topic_score_codex":0.0039865146,"about_ca_topic_score_gemma":0.0016607858,"teacher_disagreement_score":0.0039865146,"about_ca_system_score_codex":0.00045633115,"about_ca_system_score_gemma":0.0006501594,"threshold_uncertainty_score":0.007926583},"labels":[],"label_agreement":null},{"id":"W53925420","doi":"10.1023/a:1024445903306","title":"Imparting Bone Affinity to Glycoproteins Through the Conjugation of Bisphosphonates","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Bone health and treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"Canadian Institutes of Health Research; Killam Trusts; University of Alberta","keywords":"Fetuin; Conjugate; Chemistry; Conjugated system; Glycoprotein; Biochemistry; Stereochemistry; Organic chemistry; Polymer","score_opus":0.291902652479819,"score_gpt":0.5406054231365311,"score_spread":0.24870277065671215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W53925420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98541415,0.0016175073,0.0063741687,0.0003203477,0.00006568179,0.000044207663,0.00005401343,0.000062530125,0.00604736],"genre_scores_gemma":[0.9887007,0.0016456112,0.0037797566,0.00013224773,0.000015908694,0.000017253678,0.00008780159,0.000020918287,0.005599837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998616,0.000037677684,0.0000053363765,0.000014644089,0.00003071291,0.00004991544],"domain_scores_gemma":[0.999933,0.000015440151,0.000012433706,0.000009808855,0.000011282906,0.00001798905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018315218,0.00037859948,0.00020143297,0.00020486933,0.00023263847,0.00050072063,0.00024080307,0.0005163845,0.0011451385],"category_scores_gemma":[0.00026365148,0.00019329609,0.00026841604,0.00021665683,0.00025485014,0.0002217094,0.00043773712,0.0005578889,0.00044815984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017292467,0.00005252812,0.00013823106,0.000042059943,0.000012285131,0.0001042111,0.000051865478,0.00030318648,0.9923111,0.001680182,0.00018547472,0.0049459385],"study_design_scores_gemma":[0.000020091995,0.00019577763,0.00059404265,0.0000065538247,0.000022364384,0.00014632138,0.000022371614,0.00085843034,0.9895695,0.00013525628,0.008420722,0.000008596268],"about_ca_topic_score_codex":0.0012090298,"about_ca_topic_score_gemma":0.001670771,"teacher_disagreement_score":0.0012090298,"about_ca_system_score_codex":0.00040321183,"about_ca_system_score_gemma":0.00022474055,"threshold_uncertainty_score":0.0038308501},"labels":[],"label_agreement":null},{"id":"W568977620","doi":"10.1007/s11095-015-1713-3","title":"Monitoring Effects of Excipients, Formulation Parameters and Mutations on the High Order Structure of Filgrastim by NMR","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Institute of General Medical Sciences","keywords":"Filgrastim; Biosimilar; Chemistry; Nuclear magnetic resonance spectroscopy; Pharmacology; Stereochemistry; Medicine; Organic chemistry; Internal medicine; Toxicity; Neutropenia","score_opus":0.15074950243313853,"score_gpt":0.44796324332358706,"score_spread":0.2972137408904485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W568977620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961365,0.00036875275,0.0023589612,0.00008059076,0.000015586487,0.000020781676,0.00026814008,0.00006503866,0.00068567763],"genre_scores_gemma":[0.99148047,0.0004919175,0.0060782437,0.0000852557,0.000011406029,0.000045160752,0.00041363598,0.000060123755,0.0013336662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99970394,0.00007734665,0.000021105629,0.000054314194,0.00008981623,0.000053439195],"domain_scores_gemma":[0.9994048,0.0002544933,0.00012148047,0.000057461515,0.00011901092,0.00004268459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047771353,0.0003147643,0.00028091262,0.00017666291,0.00023399724,0.00034050125,0.00020478378,0.00037247982,0.0013248275],"category_scores_gemma":[0.0011599344,0.00016475095,0.00020857224,0.00029791472,0.00035129106,0.00034965234,0.00020359173,0.00063413207,0.00022841628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029208546,0.00003226563,0.00035966057,0.00002876889,0.0000073707834,0.000019354587,0.000044501863,0.00029537495,0.9970642,0.00003812866,0.000044281252,0.0017740659],"study_design_scores_gemma":[0.0000062933673,0.00016117482,0.0014278053,0.0000026898779,0.000014175372,0.000028111277,0.00001866469,0.0014540041,0.9965127,0.000015739593,0.00035060683,0.000008017973],"about_ca_topic_score_codex":0.0011836179,"about_ca_topic_score_gemma":0.0012075485,"teacher_disagreement_score":0.0013248275,"about_ca_system_score_codex":0.00034462017,"about_ca_system_score_gemma":0.0002897575,"threshold_uncertainty_score":0.0044320226},"labels":[],"label_agreement":null},{"id":"W58893836","doi":"10.1023/a:1010987212724","title":"Effects of Food on the Pharmacokinetics of Methylphenidate","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; BioPhage Pharma (Canada)","funders":"MetLife Foundation","keywords":"Cmax; Pharmacokinetics; Crossover study; Chemistry; Absorption (acoustics); Pharmacology; Animal science; Medicine; Placebo; Biology; Materials science","score_opus":0.3049891004538657,"score_gpt":0.5279589548506398,"score_spread":0.22296985439677414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W58893836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966118,0.0012833276,0.0002450894,0.00022410956,0.00008217723,0.000028288727,0.00036401243,0.000047079247,0.0011140885],"genre_scores_gemma":[0.99611413,0.0009818812,0.00061498693,0.00017670414,0.000077274686,0.000035813413,0.0003826008,0.000050517872,0.0015660675],"study_design_codex":"randomized_trial","study_design_gemma":"observational","domain_scores_codex":[0.99958986,0.00021193344,0.000021101992,0.00005640711,0.00005734246,0.000063377294],"domain_scores_gemma":[0.998049,0.0010096108,0.0003150833,0.00019813696,0.00013689487,0.0002912572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047079474,0.0006287268,0.00094480533,0.00028283164,0.00037865323,0.0006840279,0.00026599507,0.0010733457,0.0031957289],"category_scores_gemma":[0.003553755,0.0007211379,0.0007015059,0.00025316988,0.00075147394,0.0011239081,0.000334004,0.0016179573,0.0005222657],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.75075585,0.0027332394,0.013679797,0.00030380534,0.00082031987,0.00078189967,0.00033588955,0.0007717363,0.16617447,0.0003837558,0.0013050397,0.061954144],"study_design_scores_gemma":[0.027562028,0.23021452,0.40610233,0.00014302462,0.0031585137,0.0037162676,0.000990689,0.014730579,0.30099702,0.0015427852,0.010534425,0.0003078318],"about_ca_topic_score_codex":0.0030169655,"about_ca_topic_score_gemma":0.003294548,"teacher_disagreement_score":0.0031957289,"about_ca_system_score_codex":0.0008246648,"about_ca_system_score_gemma":0.0008244275,"threshold_uncertainty_score":0.010690808},"labels":[],"label_agreement":null},{"id":"W71576337","doi":"10.1023/a:1011015924429","title":"Evaluation of the Bioequivalence of Highly-Variable Drugs and Drug Products","year":2001,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Bioequivalence; Mathematics; Statistics; Variable (mathematics); Power (physics); Geometric mean; Statistical analysis; Applied mathematics; Econometrics; Pharmacokinetics; Pharmacology; Thermodynamics; Mathematical analysis; Medicine","score_opus":0.8858350907793737,"score_gpt":0.7094881880146106,"score_spread":0.17634690276476317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W71576337","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":"methods","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":"methods","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25426826,0.008028028,0.7336166,0.0013364373,0.00012770714,0.0003697352,0.00017604636,0.00017943521,0.0018977431],"genre_scores_gemma":[0.9042274,0.0013083606,0.09311438,0.0002531848,0.0001433441,0.0003284391,0.00016705264,0.000054526336,0.00040331218],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.908957,0.08235434,0.002226632,0.0015052913,0.0046140105,0.00034277918],"domain_scores_gemma":[0.62190723,0.3575468,0.00956714,0.0075450395,0.0027842997,0.0006495115],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.09070877,0.00084621523,0.0027296413,0.0012991985,0.0002498404,0.0016045468,0.0013070811,0.001531081,0.0016953384],"category_scores_gemma":[0.24119787,0.00040327504,0.0017300682,0.00092226494,0.0024236343,0.0020724798,0.0013093387,0.0014684554,0.00014612525],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.029457781,0.0013010319,0.02520589,0.0031391147,0.008842139,0.00031394098,0.00060400984,0.31631482,0.008843533,0.14345798,0.0018076997,0.46071213],"study_design_scores_gemma":[0.0017907887,0.016820658,0.015914168,0.00024042386,0.0023992627,0.0006171196,0.00015394304,0.76640713,0.010739057,0.18136823,0.0034446192,0.000104574654],"about_ca_topic_score_codex":0.00026800382,"about_ca_topic_score_gemma":0.00017052058,"teacher_disagreement_score":0.9092912,"about_ca_system_score_codex":0.0010263133,"about_ca_system_score_gemma":0.0020631135,"threshold_uncertainty_score":0.47971958},"labels":[],"label_agreement":null},{"id":"W782389661","doi":"10.1007/s11095-015-1741-z","title":"Effect of siRNA pre-Exposure on Subsequent Response to siRNA Therapy","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Cure Brain Cancer Foundation; Natural Sciences and Engineering Research Council of Canada; Georgetown University","keywords":"Gene silencing; Small interfering RNA; RNA interference; In vivo; Messenger RNA; Viability assay; Cancer cell; In vitro; Cancer research; Cell; Biology; Cancer; Chemistry; Cell biology; Molecular biology; Cell culture; Transfection; RNA; Biochemistry; Gene; Biotechnology; Genetics","score_opus":0.16285311696236832,"score_gpt":0.4969929895813249,"score_spread":0.33413987261895656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W782389661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98965853,0.0030017458,0.0019515862,0.0001871505,0.00035096006,0.00015855802,0.0005805218,0.00015679745,0.003954087],"genre_scores_gemma":[0.9881323,0.0011852583,0.0024868865,0.00015863239,0.000084764804,0.00020286895,0.000813935,0.000077873476,0.006857453],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938035,0.0001363467,0.00008911937,0.00011622714,0.00008861552,0.00018933133],"domain_scores_gemma":[0.99906987,0.00057289866,0.00006835034,0.00007784058,0.000109112756,0.0001020089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067415,0.0004509374,0.0007262332,0.00026723478,0.00027379266,0.0006517305,0.00035740566,0.0006168963,0.005646704],"category_scores_gemma":[0.000994719,0.00026570866,0.0004693833,0.00033239822,0.00040137352,0.00035641433,0.00029763082,0.000906653,0.0010666497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038556056,0.00042684702,0.00025360205,0.00009141958,0.000021441825,0.00006446061,0.00007782831,0.000117034746,0.9912683,0.00008259764,0.00019522847,0.0035457208],"study_design_scores_gemma":[0.00005085021,0.0012878736,0.0033499892,0.0000046158893,0.000030688265,0.000040564333,0.00003122786,0.0003535136,0.9938251,0.000022174892,0.0009928346,0.000010691656],"about_ca_topic_score_codex":0.0012247832,"about_ca_topic_score_gemma":0.0016618249,"teacher_disagreement_score":0.005646704,"about_ca_system_score_codex":0.00038103486,"about_ca_system_score_gemma":0.0005768506,"threshold_uncertainty_score":0.018890083},"labels":[],"label_agreement":null},{"id":"W87870904","doi":"10.1023/a:1022695819135","title":"Limits for the Scaled Average Bioequivalence of Highly Variable Drugs and Drug Products","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Bioequivalence; Mathematics; Statistics; Limit (mathematics); Confidence interval; Geometric mean; Logarithm; Linearization; Limiting; Variable (mathematics); Applied mathematics; Pharmacokinetics; Mathematical analysis; Pharmacology; Medicine; Nonlinear system; Physics","score_opus":0.7892181539649511,"score_gpt":0.6590397458225726,"score_spread":0.13017840814237847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W87870904","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.026669854,0.003802678,0.96300715,0.001366897,0.00019190184,0.00010736379,0.00014323319,0.00038292093,0.0043279207],"genre_scores_gemma":[0.6186875,0.0025118676,0.37116468,0.002237342,0.0010078213,0.0015598483,0.0003737375,0.0003509128,0.0021061685],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.950203,0.035896074,0.0022160267,0.003276165,0.007795445,0.00061323436],"domain_scores_gemma":[0.61601394,0.34979808,0.00946844,0.015864726,0.007273814,0.0015809971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.071057774,0.0011747915,0.0028901857,0.0026027372,0.00067184714,0.0049097533,0.0027897975,0.0025255182,0.0034586505],"category_scores_gemma":[0.22764151,0.0008925833,0.0023493536,0.0014621783,0.0065200743,0.0051407767,0.0043536406,0.0053622103,0.0005152286],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008342622,0.00014782412,0.0023704867,0.00091385876,0.0006372553,0.00023382604,0.00063442776,0.06588617,0.004850101,0.8286554,0.0026055258,0.09223089],"study_design_scores_gemma":[0.00011047131,0.0006636248,0.0030926857,0.00031366048,0.0002047713,0.0004274057,0.00009338395,0.3039628,0.0033302503,0.68148005,0.0062373453,0.00008352932],"about_ca_topic_score_codex":0.0004433723,"about_ca_topic_score_gemma":0.00020905284,"teacher_disagreement_score":0.071057774,"about_ca_system_score_codex":0.0016788258,"about_ca_system_score_gemma":0.0016018891,"threshold_uncertainty_score":0.37579393},"labels":[],"label_agreement":null},{"id":"W98693264","doi":"10.1023/a:1015175108183","title":"Paclitaxel-Loaded Crosslinked Hyaluronic Acid Films for the Prevention of Postsurgical Adhesions","year":2002,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Intestinal and Peritoneal Adhesions","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Surgical Specialties (Canada); University of British Columbia","funders":"","keywords":"Adhesion; Hyaluronic acid; Paclitaxel; Swelling; Carbodiimide; Abrasion (mechanical); Chemistry; Pharmacology; Dosage form; Surgery; Medicine; Chemotherapy; Materials science; Biochemistry; Anatomy; Pathology; Organic chemistry; Composite material","score_opus":0.446669892852961,"score_gpt":0.5307777790538571,"score_spread":0.08410788620089615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W98693264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870494,0.0095645245,0.0016467443,0.00014871017,0.00010807417,0.000042287393,0.000042518986,0.000045293476,0.0013525889],"genre_scores_gemma":[0.9908404,0.0049743596,0.0015233404,0.00007212745,0.000037226164,0.000017578326,0.000059624694,0.000009921777,0.0024654933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995077,0.000009828656,0.000003093113,0.0000061793894,0.000015871416,0.000014262733],"domain_scores_gemma":[0.99994767,0.000016570162,0.000013440213,0.0000030784806,0.0000061381743,0.000013121586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009598289,0.00019419835,0.00017118818,0.0002656841,0.00017262685,0.00024475987,0.00015322205,0.0002259392,0.0008732561],"category_scores_gemma":[0.0001459647,0.00013248896,0.00013129345,0.00015055304,0.00009962015,0.00021144943,0.0000880777,0.00033507112,0.00011791695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010661347,0.00039534495,0.00028318368,0.00016557513,0.000033078126,0.00020327473,0.000036078138,0.00029112346,0.971314,0.00011524565,0.00030045523,0.02579643],"study_design_scores_gemma":[0.00021003072,0.0019691018,0.0033745868,0.000021362537,0.0000988494,0.0002715212,0.000026181044,0.0010357595,0.99035114,0.00003055053,0.002602532,0.000008379304],"about_ca_topic_score_codex":0.00049496687,"about_ca_topic_score_gemma":0.00086501247,"teacher_disagreement_score":0.0008732561,"about_ca_system_score_codex":0.0001305977,"about_ca_system_score_gemma":0.00015524727,"threshold_uncertainty_score":0.0029213428},"labels":[],"label_agreement":null},{"id":"W992516122","doi":"10.1007/s11095-015-1737-8","title":"Polymeric Micelles of PEG-PLA Copolymer as a Carrier for Salinomycin Against Gemcitabine-Resistant Pancreatic Cancer","year":2015,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Public Health Agency of Canada","keywords":"Gemcitabine; In vivo; Pancreatic cancer; Salinomycin; Apoptosis; Chemistry; Micelle; Annexin; Cancer research; Cancer; Pharmacology; Biology; Medicine; Biochemistry; Internal medicine","score_opus":0.2822263460206154,"score_gpt":0.5199709514280616,"score_spread":0.23774460540744619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W992516122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994333,0.002069416,0.0019830768,0.00013473196,0.000053066393,0.000038403843,0.000055884462,0.0000643417,0.0012679098],"genre_scores_gemma":[0.99643326,0.000794564,0.0013789601,0.00003382726,0.000021853519,0.000017984858,0.00006126049,0.000011413417,0.0012468665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999454,0.00001059461,0.0000044280164,0.0000127094945,0.000010380282,0.000016482716],"domain_scores_gemma":[0.9999466,0.000010835817,0.000015545398,0.000003885408,0.000008000352,0.000015145674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017363303,0.00026741167,0.00019175812,0.00024236405,0.00013571657,0.00015849606,0.00015529287,0.00025514018,0.00076622376],"category_scores_gemma":[0.00013418873,0.00012688915,0.00016109218,0.00014050209,0.00015983768,0.00043805077,0.00015051228,0.00033840293,0.0002010751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003957425,0.000053828775,0.000070467766,0.00005405456,0.000009806847,0.000038278406,0.000018472134,0.00030559197,0.9956513,0.00012786144,0.00006381331,0.0032108198],"study_design_scores_gemma":[0.00011744195,0.0011985038,0.0009980119,0.000007665988,0.000063122985,0.00011770668,0.000010336464,0.0025876462,0.9920495,0.000041937885,0.0028016325,0.0000064595847],"about_ca_topic_score_codex":0.0008894141,"about_ca_topic_score_gemma":0.00090843684,"teacher_disagreement_score":0.0008894141,"about_ca_system_score_codex":0.00023481298,"about_ca_system_score_gemma":0.0002859039,"threshold_uncertainty_score":0.0025632381},"labels":[],"label_agreement":null}]}