{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":551,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":551,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"20d61a2bfd15","filters":{"topic":"Advancements in Transdermal Drug Delivery"}},"results":[{"id":"W2117369764","doi":"10.3109/10717541003667798","title":"Microneedle-based drug delivery systems: Microfabrication, drug delivery, and safety","year":2010,"lang":"en","type":"review","venue":"Drug Delivery","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":674,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Queen's University; Queen's University Belfast","keywords":"Transdermal; Stratum corneum; Drug delivery; Materials science; Drug; Nanotechnology; Lipophilicity; Biomedical engineering; Pharmacology; Chemistry; Medicine; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.06318873005189003,"gpt":0.3821650178854543,"spread":0.3189762878335642,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.003042912,0.002569166,0.004071033,0.001221165,0.001460653,0.0002642362,0.002347053,0.002085748,0.0009409653],"category_scores_gemma":[0.00009740277,0.002596074,0.001292735,0.001037433,0.00143754,0.0007330862,0.0007513905,0.006237219,0.001867854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001174224,"about_ca_system_score_gemma":0.001883472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008776952,"about_ca_topic_score_gemma":0.0003049742,"domain_scores_codex":[0.9873561,0.003044115,0.003282584,0.002709337,0.0009115147,0.002696402],"domain_scores_gemma":[0.9906744,0.003394513,0.001874286,0.001807871,0.0008828426,0.001366125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006056459,0.001008433,0.0002129884,0.01967127,0.00185104,0.0004199067,0.001294181,0.000316045,0.0004870666,0.0001043215,0.05991105,0.9141181],"study_design_scores_gemma":[0.002710334,0.00004067926,0.00001123072,0.00409037,0.004706177,0.0001663164,0.0003359606,0.0009819027,0.00048584,0.00002836794,0.9839335,0.002509315],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008551057,0.9744726,0.0002140248,0.0002985132,0.006873203,0.004509379,0.003040113,0.0005948935,0.00144621],"genre_scores_gemma":[0.001653363,0.9854299,0.0008209324,0.002038131,0.001313833,0.0007591664,0.002504856,0.0004811552,0.004998602],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9240224,"threshold_uncertainty_score":0.9999723,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2043308790","doi":"10.1007/s10544-008-9208-1","title":"Clinical administration of microneedles: skin puncture, pain and sensation","year":2008,"lang":"en","type":"article","venue":"Biomedical Microdevices","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":329,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"British Skin Foundation; McGill University","keywords":"Hypodermic needle; Medicine; Visual analogue scale; Transdermal; Biomedical engineering; Anesthesia; Materials science; Syringe; Pharmacology","retraction":null,"screen_n_in":null,"score":{"opus":0.1110097172780573,"gpt":0.445063777145031,"spread":0.3340540598669737,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001318499,0.0001721868,0.0002938921,0.00008806481,0.0001403638,0.000004768532,0.0001540613,0.0003999898,0.0003313777],"category_scores_gemma":[0.0001515707,0.000149332,0.00007945046,0.0001510389,0.001172736,0.00009827479,0.00004371348,0.0004105054,0.00002894595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000191965,"about_ca_system_score_gemma":0.00009964051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001355152,"about_ca_topic_score_gemma":0.00001025655,"domain_scores_codex":[0.9979619,0.0006296496,0.0006660293,0.0003150846,0.0001813472,0.0002459745],"domain_scores_gemma":[0.9987128,0.0006665365,0.0002085961,0.0001304456,0.00007547966,0.0002061435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00177349,0.003118582,0.1248429,0.0009329315,0.0006854337,0.0002784765,0.00328031,0.00001736304,0.2814368,0.0003380795,0.02271342,0.5605822],"study_design_scores_gemma":[0.00382229,0.001239599,0.07039642,0.0001010223,0.0002411013,0.0002371413,0.0006019984,0.002153123,0.06501392,0.0002527019,0.8553832,0.0005575377],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904162,0.002008316,0.005362145,0.0006964516,0.0007750977,0.0002845845,0.00008509629,0.0000480271,0.0003240579],"genre_scores_gemma":[0.9929496,0.001509272,0.002925728,0.00201353,0.0002807647,0.000009411609,0.0001036716,0.00001351328,0.0001945327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8326697,"threshold_uncertainty_score":0.6089582,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4317500685","doi":"10.1038/s41551-022-00998-9","title":"Opportunities and challenges in the diagnostic utility of dermal interstitial fluid","year":2023,"lang":"en","type":"review","venue":"Nature Biomedical Engineering","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":325,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Air Force Office of Scientific Research; Division of Chemical, Bioengineering, Environmental, and Transport Systems; Office of Naval Research; Natural Sciences and Engineering Research Council of Canada; U.S. Air Force; Sandia National Laboratories; National Nuclear Security Administration; U.S. Department of Health and Human Services; National Institutes of Health; National Science Foundation; Division of Electrical, Communications and Cyber Systems; U.S. Department of Energy; U.S. Department of Defense; University of Cincinnati; Medtronic Foundation; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Interstitial fluid; Medicine; Tissue fluid; Immune system; Body fluid; Dermis; Pathology; Intensive care medicine; Immunology","retraction":null,"screen_n_in":null,"score":{"opus":0.3472412409062192,"gpt":0.4649250292558288,"spread":0.1176837883496096,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0009901354,0.0003544669,0.0008665583,0.0003155353,0.00004012762,0.00000688806,0.0004857209,0.001360807,0.00009756404],"category_scores_gemma":[0.0008403785,0.0002563221,0.0001557285,0.0002671016,0.0003500846,0.00005489012,0.0001468558,0.002831608,0.000007331995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003721947,"about_ca_system_score_gemma":0.00009587163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000249769,"about_ca_topic_score_gemma":0.000003265379,"domain_scores_codex":[0.9980984,0.0003107674,0.0006024214,0.0003201717,0.000288275,0.0003799131],"domain_scores_gemma":[0.9950755,0.004459713,0.0001054904,0.0001960738,0.0000248296,0.0001384301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001391281,0.0001099405,0.000001449692,0.02948106,0.0002492911,0.0004487178,0.0003283151,0.00001279639,0.000002072187,0.0009941717,0.0004454624,0.9679128],"study_design_scores_gemma":[0.0002722977,0.00004351932,0.00002191351,0.003368364,0.000354564,0.00006490616,0.0001221478,0.0008615918,0.000002724654,0.00001635712,0.9946615,0.0002101867],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003363233,0.9967839,0.00009953565,0.0004547928,0.001688587,0.0004888488,0.0002281489,0.00006668874,0.0001558281],"genre_scores_gemma":[0.002664137,0.9965354,0.00004218467,0.0001169648,0.0003674435,0.0001110765,0.0001112188,0.00003888245,0.00001270762],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.994216,"threshold_uncertainty_score":0.9999889,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2936156980","doi":"10.1016/j.msec.2019.04.063","title":"3D printed microneedle patches using stereolithography (SLA) for intradermal insulin delivery","year":2019,"lang":"en","type":"article","venue":"Materials Science and Engineering C","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":303,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Seventh Framework Programme; European Research Council; European Commission; Ministério da Educação; Queen's University; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Queen's University Belfast","keywords":"Stereolithography; Materials science; Transdermal; Penetration (warfare); Insulin delivery; Biomedical engineering; 3d printed; Insulin; 3D printing; Biocompatible material; Nanotechnology; Composite material; Medicine; Pharmacology; Diabetes mellitus","retraction":null,"screen_n_in":null,"score":{"opus":0.05776422883508309,"gpt":0.353246029010144,"spread":0.2954818001750609,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007221028,0.0001882433,0.0002212741,0.0001968179,0.000193165,0.00006869324,0.0002487148,0.0001166093,0.0001561254],"category_scores_gemma":[0.00003579455,0.0001861265,0.00002995564,0.0002431582,0.0002599791,0.0003633672,0.00009822253,0.0001474918,0.00001759322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005518305,"about_ca_system_score_gemma":0.00006133273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000150065,"about_ca_topic_score_gemma":4.514183e-7,"domain_scores_codex":[0.9986922,0.00002998948,0.0002582102,0.0003459153,0.0001496755,0.0005240286],"domain_scores_gemma":[0.9994827,0.00009004875,0.00005798629,0.0001421298,0.0000994937,0.0001276548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000988471,0.00003623925,0.001056265,0.0001896248,0.00002738533,0.000002758987,0.0003490303,0.005660375,0.9905294,0.0001372004,0.00001245052,0.001900448],"study_design_scores_gemma":[0.001276775,0.0001058883,0.003645033,0.00005968094,0.00005796002,0.00002712847,0.0001468103,0.04418387,0.9404418,0.00003243913,0.009627172,0.0003954714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941093,0.0002309102,0.003017167,0.00004726762,0.001884082,0.0004988789,0.00008106555,0.00008050126,0.00005083916],"genre_scores_gemma":[0.9919081,0.00009640697,0.007492975,0.0003031451,0.0001163005,0.00002686538,0.000007547694,0.00002117572,0.0000274998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0500876,"threshold_uncertainty_score":0.759002,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3134060153","doi":"10.1016/j.ijpharm.2021.120455","title":"Hollow microneedles: A perspective in biomedical applications","year":2021,"lang":"en","type":"review","venue":"International Journal of Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":277,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"H2020 Marie Skłodowska-Curie Actions; Queen's University; Lembaga Pengelola Dana Pendidikan; Queen's University Belfast; European Commission","keywords":"Stratum corneum; Nanotechnology; Drug delivery; Fabrication; Materials science; Biomedical engineering; Delivery system; Medicine; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.2089330403268869,"gpt":0.5723317682269573,"spread":0.3633987279000704,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001022498,0.0005026521,0.001479041,0.001071091,0.00006969607,0.00005273167,0.001630208,0.000656603,0.001255673],"category_scores_gemma":[0.0001893876,0.0004739432,0.0008446462,0.0006144093,0.0003563939,0.0002193413,0.0002369196,0.003554481,0.0001243973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001459047,"about_ca_system_score_gemma":0.001271131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005555471,"about_ca_topic_score_gemma":0.000003554638,"domain_scores_codex":[0.9957422,0.0007706183,0.001848251,0.0004078633,0.0007797109,0.0004513435],"domain_scores_gemma":[0.9962488,0.0008902266,0.001229176,0.0001995089,0.001091357,0.0003409757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009555205,0.001578295,0.00002560124,0.0009875823,0.002973009,0.002117169,0.0005767801,0.0001493032,0.0001357649,0.001053636,0.001142297,0.989165],"study_design_scores_gemma":[0.001824782,0.00004014116,7.270087e-7,0.002536141,0.00134809,0.001356032,0.0004347638,0.00007900842,0.0001676804,0.0001817065,0.991662,0.0003689364],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001416979,0.9895036,0.00313445,0.0004497554,0.004848223,0.0005982641,0.0004118084,0.00001990542,0.001019802],"genre_scores_gemma":[0.0002501593,0.9952369,0.001254332,0.0007871552,0.001871357,0.00008225723,0.0001259012,0.0000704401,0.0003214819],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9905197,"threshold_uncertainty_score":0.9997712,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2620373091","doi":"10.3390/nano7060122","title":"A Review of the Structure, Preparation, and Application of NLCs, PNPs, and PLNs","year":2017,"lang":"en","type":"review","venue":"Nanomaterials","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":270,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"Science and Technology Planning Project of Guangdong Province; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Nanotechnology; Biocompatibility; Drug delivery; Nanoparticle; Solid lipid nanoparticle; Drug; Materials science; Polymer; Liposome; Controlled release; Drug carrier; Pharmacology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.1537963059010543,"gpt":0.5170292721511076,"spread":0.3632329662500533,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005656723,0.0002517212,0.001279143,0.00004023501,0.0001341907,0.000009837744,0.0003631033,0.0003470945,0.000161902],"category_scores_gemma":[0.0001267391,0.000168354,0.0001071488,0.00005467135,0.0003880777,0.00007306242,0.0001505938,0.0001566674,0.000002852262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001991012,"about_ca_system_score_gemma":0.0001114265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006172687,"about_ca_topic_score_gemma":0.000002677923,"domain_scores_codex":[0.9980425,0.0005887034,0.0008577215,0.0002750499,0.0001001167,0.0001358888],"domain_scores_gemma":[0.9977825,0.0001768201,0.001439226,0.0004684646,0.00008826806,0.00004477268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003058479,0.00003991036,0.0000313603,0.2301931,0.0002732522,5.803377e-7,0.00006905536,6.226017e-7,0.001959083,0.0004191748,0.0007157065,0.7662676],"study_design_scores_gemma":[0.0001953539,0.00002362761,0.0000130791,0.01321502,0.001307928,0.00002648121,9.001897e-7,0.000002331705,0.002803802,0.0001426696,0.9821321,0.0001366542],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003282935,0.9956599,0.00001912097,0.0000209912,0.0006291772,0.002035951,0.00113039,0.000009868613,0.0001663438],"genre_scores_gemma":[0.001274008,0.9980899,0.00009515088,0.0001601997,0.00009767551,0.00008955324,0.00009111336,0.00002075735,0.00008161862],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9814165,"threshold_uncertainty_score":0.6865277,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3160176851","doi":"10.1016/j.mattod.2021.03.012","title":"Stimuli-responsive transdermal microneedle patches","year":2021,"lang":"en","type":"article","venue":"Materials Today","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":265,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Transdermal; Stratum corneum; Dermis; Drug delivery; Site of action; Nanotechnology; Biomedical engineering; Materials science; Medicine; Anatomy; Pharmacology; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.1103181804153518,"gpt":0.4254368426505339,"spread":0.315118662235182,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004348686,0.0003037627,0.0004027864,0.00006391077,0.0002469933,0.00004778578,0.0002606729,0.0003319248,0.02785458],"category_scores_gemma":[0.00007764565,0.0003146254,0.00009994779,0.0001502303,0.0002026504,0.0001854966,0.00009056554,0.0003567513,0.000985652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006371941,"about_ca_system_score_gemma":0.0001416725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001564351,"about_ca_topic_score_gemma":0.000010424,"domain_scores_codex":[0.9975065,0.0007803683,0.0004919204,0.0004587231,0.0001543081,0.0006081575],"domain_scores_gemma":[0.9989685,0.0003065341,0.00009900484,0.000290865,0.0001456053,0.0001894934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006187925,0.000292773,0.0002526817,0.0000887292,0.0001749964,0.000476492,0.001062868,0.0004969052,0.9876897,0.0002983293,0.003801458,0.004746321],"study_design_scores_gemma":[0.001401739,0.00004424816,0.0007907597,0.00001809347,0.0001109821,0.00006677396,0.0002116576,0.00002668785,0.8103718,0.0002952262,0.186366,0.0002960819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884552,0.001082288,0.001108899,0.001676621,0.003763417,0.0003335425,0.0006727873,0.0001639286,0.002743285],"genre_scores_gemma":[0.9889053,0.0004444509,0.001029204,0.004708384,0.0004066771,0.0000658496,0.0001860072,0.00005198079,0.004202182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1825645,"threshold_uncertainty_score":0.9999306,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4366261646","doi":"10.1016/j.bioactmat.2023.04.003","title":"Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration","year":2023,"lang":"en","type":"review","venue":"Bioactive Materials","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":244,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Young Scientists Fund; Hong Kong Polytechnic University; Science Fund for Creative Research Groups; National Natural Science Foundation of China","keywords":"Transdermal; Regeneration (biology); Stratum corneum; Wound healing; Biomedical engineering; Drug delivery; Nanotechnology; Materials science; Medicine; Pharmacology; Surgery; Biology; Pathology; Cell biology","retraction":null,"screen_n_in":null,"score":{"opus":0.1135223422019756,"gpt":0.4441556827807043,"spread":0.3306333405787287,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007701027,0.0004453412,0.0009094097,0.00009398201,0.0007440205,0.0001850991,0.000179756,0.0004753938,0.00009304886],"category_scores_gemma":[0.00004216853,0.0003514956,0.00003698556,0.0001439735,0.000362944,0.0001418353,0.0001431158,0.0002236923,0.00001443741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009076529,"about_ca_system_score_gemma":0.00007905209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002339992,"about_ca_topic_score_gemma":0.000006573491,"domain_scores_codex":[0.9976789,0.0005912711,0.0006753604,0.0006160361,0.00009892349,0.0003395498],"domain_scores_gemma":[0.9982809,0.0007714286,0.0005047048,0.0002321235,0.0001144132,0.00009641367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002546814,0.00009508032,0.000007907189,0.02869594,0.001584622,0.000003186587,0.001387627,0.00002620896,0.3046585,0.00576472,0.001932308,0.6555893],"study_design_scores_gemma":[0.0004665756,0.00004058595,0.000009069431,0.0002683943,0.001169652,0.0000241866,0.0001201277,0.00000867771,0.08243741,0.0011449,0.9138981,0.0004123461],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00734546,0.9723105,0.001560983,0.0002169632,0.001498547,0.006517144,0.01043467,0.00009102961,0.00002475017],"genre_scores_gemma":[0.00167115,0.993288,0.0009940509,0.0002176808,0.000798804,0.0009264025,0.001618136,0.00009709112,0.00038867],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9119658,"threshold_uncertainty_score":0.9998937,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2014054988","doi":"10.1111/srt.12037","title":"International guidelines for the<i>in vivo</i>assessment of skin properties in non‐clinical settings: Part 2. transepidermal water loss and skin hydration","year":2013,"lang":"en","type":"article","venue":"Skin Research and Technology","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":235,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Michael's Hospital","funders":"National Institutes of Health","keywords":"Transepidermal water loss; Medicine; Medical physics; Computer science; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.2236908432367075,"gpt":0.5310141351844223,"spread":0.3073232919477148,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002613688,0.0001503314,0.000278506,0.0004013179,0.0001455465,0.00002093441,0.0003441441,0.000358234,0.0002769022],"category_scores_gemma":[0.0002614066,0.0001004049,0.00003780537,0.0002093802,0.00132121,0.0001782788,0.0001686257,0.0009192909,0.00000501657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003750841,"about_ca_system_score_gemma":0.00005465844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009696512,"about_ca_topic_score_gemma":0.0001963644,"domain_scores_codex":[0.997853,0.0002734329,0.0007452906,0.0003769788,0.0002116626,0.0005395808],"domain_scores_gemma":[0.9985626,0.0006609031,0.00006627537,0.0001674388,0.0004805401,0.00006225164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001363938,0.002475485,0.1831105,0.0007059046,0.0006141817,0.00008459075,0.002433039,0.001391073,0.1180434,0.005111214,0.01361466,0.671052],"study_design_scores_gemma":[0.01357807,0.001822891,0.01946346,0.0003074981,0.000067447,0.00007775061,0.004062895,0.1833274,0.4148946,0.01877441,0.3429447,0.0006788922],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9592289,0.0005689586,0.0007943847,0.03704738,0.0002921143,0.001644109,0.0000348274,0.00002285618,0.0003664493],"genre_scores_gemma":[0.9946654,0.002439335,0.001151303,0.0004421006,0.0001198871,0.0008170318,0.00001228514,0.00001508657,0.0003375274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6703731,"threshold_uncertainty_score":0.4868052,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2980442678","doi":"10.1016/j.jconrel.2019.10.022","title":"Polymeric microneedles for controlled transdermal drug delivery","year":2019,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":224,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Cape Breton University","funders":"Canada Research Chairs; China Postdoctoral Science Foundation; Cape Breton University","keywords":"Transdermal; Drug delivery; Stratum corneum; Drug; Controlled release; Biocompatible material; Systemic circulation; Pharmacology; Nanotechnology; Biomedical engineering; Chemistry; Materials science; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.1203973175907222,"gpt":0.453359457677718,"spread":0.3329621400869958,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002466918,0.001265452,0.009938915,0.0009168503,0.0003100557,0.00006804935,0.001260785,0.0009414958,0.0007861643],"category_scores_gemma":[0.00040818,0.0009216999,0.006657051,0.000315961,0.0002908027,0.0003535777,0.00005797929,0.003109633,0.0001657938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003464724,"about_ca_system_score_gemma":0.001956734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004947726,"about_ca_topic_score_gemma":0.000003106433,"domain_scores_codex":[0.9911045,0.002220846,0.004292094,0.0005815094,0.0005968833,0.001204112],"domain_scores_gemma":[0.9866094,0.007123775,0.004426003,0.0004413888,0.0007170445,0.000682369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.04251518,0.00112849,0.000002731586,0.01097507,0.01287699,0.0003941931,0.0001742783,0.0005036131,0.0001729992,0.00007757292,0.009628477,0.9215504],"study_design_scores_gemma":[0.1072907,0.0003976717,1.97253e-7,0.002519544,0.02679297,0.0003715371,0.00005837233,0.000605807,0.00005328789,0.00003845237,0.8611187,0.0007527055],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001831464,0.9832104,0.0018775,0.0002478316,0.006149606,0.007095233,0.0005605245,0.00004539982,0.0006303843],"genre_scores_gemma":[0.0009669467,0.989897,0.0004125858,0.001181793,0.001874091,0.0004488086,0.00007555012,0.0002040814,0.004939152],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9207977,"threshold_uncertainty_score":0.9993234,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2126777024","doi":"10.1007/s11095-012-0946-7","title":"Transdermal Delivery of Molecules is Limited by Full Epidermis, Not Just Stratum Corneum","year":2012,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":214,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; McMaster University; Eli Lilly and Company","keywords":"Stratum corneum; Transdermal; Permeability (electromagnetism); Epidermis (zoology); Corneocyte; Chemistry; Dermis; Human skin; Biophysics; Biology; Pharmacology; Biochemistry; Anatomy; Membrane","retraction":null,"screen_n_in":null,"score":{"opus":0.4289729679705411,"gpt":0.5562753947471799,"spread":0.1273024267766388,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.003019838,0.0005364309,0.000652356,0.0003885949,0.0005178964,0.00003697288,0.001043466,0.0006661884,0.008672474],"category_scores_gemma":[0.0003170208,0.0005437753,0.0002988022,0.0008990856,0.001865353,0.0005968291,0.0003006145,0.004009766,0.0008205345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002005402,"about_ca_system_score_gemma":0.0002337656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003044088,"about_ca_topic_score_gemma":0.000003258776,"domain_scores_codex":[0.9915141,0.002349332,0.001045091,0.0007553954,0.001531737,0.002804298],"domain_scores_gemma":[0.9942605,0.002864996,0.000144265,0.000516927,0.0006294838,0.001583847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004586533,0.003656835,0.005316681,0.000719368,0.0006832926,0.0001012672,0.001552171,0.0001599613,0.8663078,0.002457781,0.05907748,0.05538085],"study_design_scores_gemma":[0.002960107,0.0002668102,0.0006048577,0.00004395753,0.0002585149,0.00004196968,0.0003857291,0.008945596,0.6849483,0.000129737,0.30088,0.0005343722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9489981,0.01882564,0.002566659,0.006330631,0.001849889,0.00188497,0.001573872,0.0002302868,0.01773995],"genre_scores_gemma":[0.9861882,0.006071867,0.0004203045,0.005036601,0.000417871,0.0001355341,0.0001038367,0.00009851417,0.001527299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2418025,"threshold_uncertainty_score":0.9999574,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2969303812","doi":"10.1038/s41378-019-0077-y","title":"Fabrication of sharp silicon hollow microneedles by deep-reactive ion etching towards minimally invasive diagnostics","year":2019,"lang":"en","type":"article","venue":"Microsystems & Nanoengineering","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":207,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Regional Municipality of Waterloo; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund; Industry Canada; Government of Canada; University of Waterloo; Ontario Centres of Excellence","keywords":"Deep reactive-ion etching; Materials science; Fabrication; Wafer; Etching (microfabrication); Reactive-ion etching; Passivation; Nanotechnology; Micromanipulator; Capillary action; Black silicon; Silicon; Optoelectronics; Biomedical engineering; Composite material; Computer science","retraction":null,"screen_n_in":null,"score":{"opus":0.02530477801885022,"gpt":0.3251260841527428,"spread":0.2998213061338926,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004090543,0.0004007108,0.0005490524,0.0001954826,0.0001063282,0.00002792594,0.0004185066,0.000363586,0.0001428265],"category_scores_gemma":[0.0001598861,0.0004432797,0.0001515141,0.0002720542,0.00007653976,0.0003160005,0.0001054109,0.0006029325,0.0001408423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002680061,"about_ca_system_score_gemma":0.00008192492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001030842,"about_ca_topic_score_gemma":0.00001519944,"domain_scores_codex":[0.9978381,0.0001607826,0.0007146515,0.0004879469,0.0002347926,0.0005637035],"domain_scores_gemma":[0.9983626,0.0006220116,0.0003369187,0.0003134133,0.0002143489,0.0001507093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001146471,0.0001729285,0.007088699,0.0006201278,0.0002617894,0.00001063979,0.001859082,0.009405056,0.9763842,0.00003461677,0.0005704637,0.003477723],"study_design_scores_gemma":[0.001579227,0.0001330496,0.001862087,0.0002680556,0.0001403165,0.00002077601,0.000577111,0.004455482,0.9725037,0.000006864624,0.01798381,0.0004695514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985549,0.005988989,0.00423891,0.00006274888,0.002222721,0.001016727,0.0002984805,0.0001243644,0.0004980089],"genre_scores_gemma":[0.9977077,0.0007927248,0.0005085874,0.0001631834,0.0001635766,0.00007746855,0.0001603758,0.00007560037,0.000350805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01741335,"threshold_uncertainty_score":0.9998019,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2932991390","doi":"10.2478/acph-2019-0016","title":"Transdermal patches: Design and current approaches to painless drug delivery","year":2019,"lang":"en","type":"review","venue":"Acta Pharmaceutica","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":198,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Transdermal; Medicine; Drug; Transdermal patch; Skin irritation; First pass effect; Pharmacology; Irritation; Intensive care medicine; Dermatology","retraction":null,"screen_n_in":null,"score":{"opus":0.6336601222236856,"gpt":0.4984666976929561,"spread":0.1351934245307295,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.002122414,0.001705784,0.002854399,0.0005726808,0.0004444672,0.0001079292,0.00146307,0.0009446223,0.0009334989],"category_scores_gemma":[0.00005435375,0.001591853,0.0007035113,0.0006701926,0.0004475263,0.0004052475,0.0004817138,0.004129574,0.001067642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003719392,"about_ca_system_score_gemma":0.0006498394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000519016,"about_ca_topic_score_gemma":0.000002288716,"domain_scores_codex":[0.9908741,0.003243697,0.001511706,0.001855785,0.0005833912,0.001931292],"domain_scores_gemma":[0.9944624,0.002856642,0.0004632502,0.0008031811,0.0000922548,0.001322217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002912704,0.0005611209,0.00001279991,0.02124026,0.001131414,0.00007719309,0.0009337314,0.0003560512,0.00003037963,0.00006447692,0.007324532,0.9679767],"study_design_scores_gemma":[0.001515602,0.00008855925,0.000001445759,0.002483493,0.005961014,0.00008656842,0.00007589105,0.00224032,0.0002885684,0.00003215596,0.9855776,0.001648767],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001031742,0.9837996,0.004474639,0.0004656879,0.003143532,0.006534609,0.0005425579,0.0002811963,0.0006550172],"genre_scores_gemma":[0.001994331,0.9922864,0.00126093,0.001654917,0.0006018351,0.001120583,0.0002471849,0.0003030527,0.0005307865],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9782531,"threshold_uncertainty_score":0.9999798,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2132332587","doi":"10.18433/j3201z","title":"The Tape-Stripping Technique as a Method for Drug Quantification in Skin","year":2008,"lang":"en","type":"review","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":197,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Stratum corneum; Transdermal; Stripping (fiber); Penetration (warfare); Biomedical engineering; Penetration rate; Materials science; Human skin; Chromatography; Chemistry; Pharmacology; Medicine; Composite material; Mathematics; Pathology; Engineering","retraction":null,"screen_n_in":null,"score":{"opus":0.3330672693240506,"gpt":0.6024215738256938,"spread":0.2693543045016432,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01023933,0.0007936145,0.0018118,0.0007566699,0.00131815,0.0001353751,0.00275405,0.0003816703,0.0002714932],"category_scores_gemma":[0.0008101774,0.0005318075,0.001202212,0.001713934,0.001546509,0.0006424886,0.0002043023,0.003878942,0.00005672039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000514037,"about_ca_system_score_gemma":0.001742081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002658545,"about_ca_topic_score_gemma":0.000009879548,"domain_scores_codex":[0.9906496,0.003240783,0.003027405,0.0007756709,0.0009954997,0.001310975],"domain_scores_gemma":[0.9878383,0.008927193,0.002015751,0.0002752223,0.0003959401,0.0005476031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003619888,0.0003992877,0.00001639663,0.001562073,0.0003139093,0.0001217101,0.0002001538,0.0003450711,0.0003466588,0.0007895372,0.003321123,0.9922221],"study_design_scores_gemma":[0.001842827,0.0001230698,7.93844e-7,0.001218735,0.0008902412,0.001281024,0.000106732,0.004090061,0.004631549,0.0004573882,0.9848008,0.0005567699],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003149155,0.9783798,0.01323459,0.001253925,0.003079171,0.003162741,0.00008727777,0.00004231992,0.0007286395],"genre_scores_gemma":[0.0003229633,0.9897385,0.007208161,0.0009403721,0.0009008688,0.0005437831,0.00001212344,0.00006889882,0.0002643881],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9916653,"threshold_uncertainty_score":0.999982,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2511557434","doi":"10.1038/srep32074","title":"A micromechanical comparison of human and porcine skin before and after preservation by freezing for medical device development","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":183,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Providence Health Care; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Stratum corneum; Human skin; Biomedical engineering; Materials science; Artificial skin; Medicine; Pathology; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.06772554086695408,"gpt":0.427551673912077,"spread":0.3598261330451229,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001547553,0.0001237592,0.0002187688,0.00006995766,0.0002432606,0.00001799452,0.00009409123,0.0001699161,0.000229091],"category_scores_gemma":[0.0001463279,0.00009262831,0.0000276456,0.00008425093,0.0003876915,0.0002046789,0.0001091367,0.0001302546,0.000001408823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003154756,"about_ca_system_score_gemma":0.00007401237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000380541,"about_ca_topic_score_gemma":0.0001012996,"domain_scores_codex":[0.998289,0.00006836429,0.0006398084,0.0004613351,0.0002889554,0.0002524723],"domain_scores_gemma":[0.9991788,0.0001389011,0.0002296652,0.0001705874,0.0001352343,0.0001468199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002154279,0.0004756306,0.1427647,0.000313081,0.0001543068,0.00006323982,0.001891415,0.000002368019,0.7334942,0.0003265977,0.009177985,0.111121],"study_design_scores_gemma":[0.001659922,0.0001519276,0.004566404,0.0001755461,0.0001016644,0.00006509259,0.00007895951,0.0005930042,0.7153506,0.004620153,0.2723805,0.0002561999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903899,0.0005105447,0.006921933,0.0006530755,0.00101214,0.0004460233,0.00001701053,0.00001890099,0.00003045549],"genre_scores_gemma":[0.9971375,0.00001246826,0.00147015,0.0001534627,0.00003478784,0.00007796777,0.00004603682,0.00001130884,0.001056332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2632025,"threshold_uncertainty_score":0.3777273,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3037569530","doi":"10.1016/j.ijpharm.2020.119580","title":"Development and characterisation of novel poly (vinyl alcohol)/poly (vinyl pyrrolidone)-based hydrogel-forming microneedle arrays for enhanced and sustained transdermal delivery of methotrexate","year":2020,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":177,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Versus Arthritis; Queen's University Belfast; Queen's University; Wellcome Trust","keywords":"Transdermal; Vinyl alcohol; Methotrexate; Ex vivo; Pharmacology; Transdermal patch; Chemistry; In vivo; Drug delivery; Bioavailability; Pharmacokinetics; Medicine; Surgery; In vitro; Organic chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.1291630378248827,"gpt":0.4174976600861852,"spread":0.2883346222613025,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007578376,0.000301568,0.0005215217,0.0002853055,0.0001022624,0.00001922661,0.0004040817,0.0001819602,0.00007747336],"category_scores_gemma":[0.00009941131,0.0003118176,0.0001674287,0.0001347125,0.0002664443,0.0004605422,0.00007079644,0.0005197727,7.745315e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001094264,"about_ca_system_score_gemma":0.0003051482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003392814,"about_ca_topic_score_gemma":0.000002275945,"domain_scores_codex":[0.9975634,0.0001034323,0.001284987,0.0002581236,0.0004560456,0.0003340723],"domain_scores_gemma":[0.9972532,0.0004940759,0.001087646,0.00007168132,0.0008139545,0.0002793792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004595155,0.0004250698,0.0006965592,0.00033149,0.00101072,0.0000245383,0.004728828,0.00183228,0.9261321,0.0001530405,0.00001289799,0.06005731],"study_design_scores_gemma":[0.01047934,0.0002074168,0.0002995547,0.00009994889,0.000394222,0.00005017307,0.0006885521,0.03018468,0.9454035,0.0000369875,0.01189574,0.0002598978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8632507,0.001601661,0.1324132,0.001333233,0.0006885561,0.0003806775,0.0002693209,0.00001486345,0.00004786617],"genre_scores_gemma":[0.9623076,0.0007158695,0.03460702,0.001994822,0.0002662237,0.00001259492,0.0000408304,0.00003696237,0.00001811443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09905692,"threshold_uncertainty_score":0.9999334,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2043667393","doi":"10.1002/jps.20100","title":"Development of solid lipid nanoparticles containing ionically complexed chemotherapeutic drugs and chemosensitizers","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":176,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Solid lipid nanoparticle; Zeta potential; Chemistry; Drug carrier; Nanoparticle; Polymer; Verapamil; Drug delivery; Daunorubicin; Dosage form; Nanocarriers; Drug; Nuclear chemistry; Chromatography; Combinatorial chemistry; Pharmacology; Materials science; Organic chemistry; Nanotechnology; Calcium","retraction":null,"screen_n_in":null,"score":{"opus":0.1520330596643755,"gpt":0.465023292548348,"spread":0.3129902328839725,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00220397,0.0002080429,0.0004434815,0.0001333737,0.0003655245,0.00002305768,0.0003907358,0.0001184458,0.0002313186],"category_scores_gemma":[0.00009402894,0.0001684248,0.0001006443,0.0003083882,0.001553738,0.0002889004,0.00009251479,0.0005893446,0.000009504972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001118989,"about_ca_system_score_gemma":0.0004138236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001794795,"about_ca_topic_score_gemma":0.000002451257,"domain_scores_codex":[0.9975491,0.0001801882,0.0009835103,0.0002368363,0.000542675,0.0005076631],"domain_scores_gemma":[0.9984637,0.0004422588,0.0004432186,0.00006967614,0.0001973554,0.0003837943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007299922,0.0004514604,0.0006347342,0.00007067428,0.0002273906,0.00002260702,0.003791958,0.002780096,0.911881,0.001523963,0.00002415962,0.07786196],"study_design_scores_gemma":[0.00486646,0.000399168,0.0008475675,0.0001153264,0.0001622785,0.0001724559,0.001582772,0.001802784,0.9732322,0.001098222,0.01545345,0.0002673474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945621,0.0008617194,0.001365524,0.00195839,0.0005238715,0.0001692539,0.000005975505,0.00001868591,0.0005344169],"genre_scores_gemma":[0.9784397,0.0004012373,0.01881732,0.002196785,0.0001195677,0.000002365385,4.864391e-7,0.0000112918,0.00001117357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07759461,"threshold_uncertainty_score":0.6868165,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W768236404","doi":"10.1002/9781118140505","title":"Topical and Transdermal Drug Delivery","year":2011,"lang":"en","type":"book","venue":"","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":171,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Transdermal; Drug; Pharmacology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.1019230104078697,"gpt":0.3860176250813112,"spread":0.2840946146734415,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002799521,0.000578248,0.0005757227,0.000148217,0.0002165028,0.00001660143,0.0004115883,0.001063963,0.0170563],"category_scores_gemma":[0.000007766159,0.0005646287,0.0001911899,0.00003974899,0.0006311542,0.0001666277,0.0001354095,0.002123985,0.0006290739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001202128,"about_ca_system_score_gemma":0.0002534526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000178864,"about_ca_topic_score_gemma":0.00006152342,"domain_scores_codex":[0.9976807,0.0002075778,0.0005302196,0.0006743969,0.0002247623,0.0006822913],"domain_scores_gemma":[0.9987507,0.0003280082,0.000122291,0.0002943478,0.00008288268,0.0004217311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001548566,0.000757782,0.0008727437,0.001182869,0.002143265,0.001305474,0.003412189,0.00004091136,0.0008903957,0.05643385,0.5588279,0.372584],"study_design_scores_gemma":[0.001331644,0.00007884291,0.00008976703,0.00004297288,0.0004949895,0.00005657557,0.000025705,0.0001321172,0.001519267,0.006161396,0.9893989,0.0006678523],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.003142292,0.005173248,0.0005457834,0.0003442651,0.001827525,0.0006761194,0.0001717046,0.0002454611,0.9878736],"genre_scores_gemma":[0.008546233,0.005071096,0.0006655972,0.005290763,0.0006435084,0.0000456133,0.000130068,0.00009462598,0.9795125],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.430571,"threshold_uncertainty_score":0.9996805,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2086340811","doi":"10.1016/s0168-3659(99)00274-6","title":"Cutaneous vaccination: the skin as an immunologically active tissue and the challenge of antigen delivery","year":2000,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":162,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Medicine; Transdermal; Vaccination; Poliomyelitis; Nasal administration; Immunization; Measles; Immunology; Virology; Immune system; Pharmacology","retraction":null,"screen_n_in":null,"score":{"opus":0.05962113077968913,"gpt":0.4284453961839872,"spread":0.3688242654042981,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001571254,0.0005072819,0.002777901,0.0002012374,0.0003494351,0.00003094994,0.0009986914,0.0006556239,0.002141334],"category_scores_gemma":[0.0003438696,0.0002413859,0.0008096907,0.0001864285,0.0005430863,0.0001996578,0.00007925093,0.002663899,0.00003086906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009140171,"about_ca_system_score_gemma":0.000441627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007921849,"about_ca_topic_score_gemma":0.000003355006,"domain_scores_codex":[0.9932073,0.004043759,0.001740722,0.000249106,0.0004046766,0.0003543823],"domain_scores_gemma":[0.9925323,0.004180836,0.002327315,0.0003644883,0.0004191218,0.0001759924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01528815,0.0004452003,3.972853e-7,0.0004796554,0.003011278,0.000459825,0.0006201215,0.0002033637,0.000005193334,0.0005168474,0.000107562,0.9788624],"study_design_scores_gemma":[0.01760042,0.001002671,0.000003377238,0.0006839705,0.005314008,0.002035547,0.0001931433,0.0001764319,0.00002680067,0.001197639,0.9714823,0.000283621],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001193185,0.9922212,0.00005031569,0.0009077391,0.0006344264,0.002073822,0.00004874627,0.00001191237,0.002858652],"genre_scores_gemma":[0.02686933,0.9715501,0.00002925223,0.0004670627,0.0005114375,0.0000612984,0.000008376236,0.00003862852,0.0004644967],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9785788,"threshold_uncertainty_score":0.999637,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2949627837","doi":"10.1002/adma.201901051","title":"Glucose‐Responsive Composite Microneedle Patch for Hypoglycemia‐Triggered Delivery of Native Glucagon","year":2019,"lang":"en","type":"article","venue":"Advanced Materials","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":159,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Juvenile Diabetes Research Foundation Canada","keywords":"Hypoglycemia; Glucagon; Insulin; Transdermal; Phenylboronic acid; Diabetes mellitus; Medicine; Internal medicine; Endocrinology; Materials science; Pharmacology; Chemistry; Biochemistry; Catalysis","retraction":null,"screen_n_in":null,"score":{"opus":0.0488029815669964,"gpt":0.3931102932876078,"spread":0.3443073117206114,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006025418,0.0003852129,0.0007566684,0.0001552232,0.0001490391,0.00001118738,0.000402912,0.0003233312,0.001529193],"category_scores_gemma":[0.00009877085,0.0003960491,0.0001508788,0.0001710548,0.0002155404,0.0003497363,0.0001208602,0.0002578948,0.0002205772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001772376,"about_ca_system_score_gemma":0.0001244643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002686053,"about_ca_topic_score_gemma":0.000004911856,"domain_scores_codex":[0.9974286,0.0003793446,0.0007822773,0.0005404703,0.0002468291,0.0006224568],"domain_scores_gemma":[0.997288,0.001198419,0.0004815793,0.000349743,0.0005483977,0.0001338936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01080534,0.0002776378,0.0002094559,0.000343245,0.0002829685,0.00001021144,0.0005364675,0.001754528,0.9789877,0.0003965276,0.0003672944,0.006028656],"study_design_scores_gemma":[0.006090607,0.0004393084,0.0001934005,0.00007413932,0.0001468522,0.000008958603,0.0002644716,0.0001043476,0.9442581,0.0008615393,0.04716228,0.0003959728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892482,0.001298776,0.001051337,0.00009713822,0.003347174,0.002180164,0.001954057,0.00008978422,0.0007333786],"genre_scores_gemma":[0.9903538,0.00105349,0.006033077,0.0009354707,0.0001381204,0.0002283274,0.0002318183,0.00007013101,0.0009557157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04679498,"threshold_uncertainty_score":0.9998491,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2106058187","doi":"10.1073/pnas.0908842106","title":"Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":154,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Institute of Biomedical Imaging and Bioengineering","keywords":"Adjuvant; Immunization; Intradermal injection; Medicine; Vaccination; Antigen; Immune system; Immunology","retraction":null,"screen_n_in":null,"score":{"opus":0.1145754254873427,"gpt":0.4284781844092417,"spread":0.3139027589218991,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009552147,0.0001400634,0.0001911608,0.0001273231,0.0003640959,0.00001241422,0.000824312,0.0001750665,0.00005519566],"category_scores_gemma":[0.0001624298,0.0001070473,0.0001098339,0.0005213996,0.000647952,0.0004139368,0.00006442769,0.0003167289,0.000001785217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005180488,"about_ca_system_score_gemma":0.00004341354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000170756,"about_ca_topic_score_gemma":1.445843e-8,"domain_scores_codex":[0.9983823,0.00001452401,0.0004421426,0.0002586968,0.0006335463,0.0002687337],"domain_scores_gemma":[0.9990582,0.0001493975,0.0004102007,0.00001029213,0.0003146349,0.00005729253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005042953,0.0006151848,0.006702403,0.0001945544,0.0001590633,4.277604e-8,0.001919471,0.00290823,0.7607208,0.1500962,0.003789486,0.07239023],"study_design_scores_gemma":[0.0009629803,0.0001749092,0.02281586,0.00005547024,0.00007019312,0.000008943633,0.0001799157,0.01687528,0.9014904,0.05261549,0.00457299,0.0001775855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9416624,0.007228555,0.0003597323,0.03644928,0.0003744157,0.001666025,0.0002628946,0.00007754108,0.01191917],"genre_scores_gemma":[0.9929996,0.0002676621,0.001698638,0.004710339,0.0001215474,0.00001728626,7.485386e-7,0.000005861655,0.0001782984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1407695,"threshold_uncertainty_score":0.4365264,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2947594527","doi":"10.1016/j.jconrel.2019.05.038","title":"Strategy for hypertrophic scar therapy: Improved delivery of triamcinolone acetonide using mechanically robust tip-concentrated dissolving microneedle array","year":2019,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":153,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Triamcinolone acetonide; Transdermal; Hypertrophic scar; Drug delivery; Hyaluronic acid; Syringe; Biomedical engineering; Medicine; Sodium hyaluronate; Chemistry; Surgery; Pharmacology; Anatomy; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.1062964704853679,"gpt":0.3833792678351156,"spread":0.2770827973497477,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001276514,0.0003790272,0.001404565,0.0002231477,0.0001625974,0.00002796741,0.0004714153,0.0004122578,0.0004883157],"category_scores_gemma":[0.0002086416,0.0003053551,0.0006816875,0.0001990403,0.0001421616,0.0003592087,0.00002741487,0.0009888767,0.000007694414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001708838,"about_ca_system_score_gemma":0.0005826035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001233463,"about_ca_topic_score_gemma":0.000002474898,"domain_scores_codex":[0.9965686,0.0006076327,0.001603519,0.0003017568,0.000293067,0.0006254035],"domain_scores_gemma":[0.9958628,0.001094202,0.001601344,0.0002498499,0.0009034427,0.0002883053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04784468,0.000641924,0.0002854784,0.00008343608,0.001607966,0.0000364738,0.0001217709,0.0706771,0.873675,0.00005492537,0.0000581175,0.004913078],"study_design_scores_gemma":[0.1837165,0.003832526,0.0001276964,0.0002822526,0.002106707,0.0001910509,0.0006720478,0.229539,0.5758558,0.0003770936,0.002519796,0.00077957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9725989,0.008037,0.01551265,0.0002550471,0.001585353,0.001834969,0.00006800837,0.00002204558,0.00008606893],"genre_scores_gemma":[0.9932675,0.002424311,0.003071209,0.0005639803,0.0003410564,0.00001833041,0.000007481035,0.00005927954,0.0002468013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2978193,"threshold_uncertainty_score":0.9999399,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2094686752","doi":"10.1007/s11095-010-0227-2","title":"Microneedle Pre-treatment of Human Skin Improves 5-Aminolevulininc Acid (ALA)- and 5-Aminolevulinic Acid Methyl Ester (MAL)-Induced PpIX Production for Topical Photodynamic Therapy Without Increase in Pain or Erythema","year":2010,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":150,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"Biotechnology and Biological Sciences Research Council; Invest Northern Ireland; Kreftforeningen","keywords":"Erythema; Photodynamic therapy; Protoporphyrin IX; Dermatology; Medicine; Chemistry; Protoporphyrin; Pharmacology; Porphyrin; Photochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.2673882479678723,"gpt":0.5435916272016829,"spread":0.2762033792338106,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004016769,0.0005015158,0.0007433235,0.0005248604,0.0004019793,0.00004736241,0.0005184656,0.0006270213,0.000484734],"category_scores_gemma":[0.0007565492,0.0004092175,0.0001693138,0.0004835356,0.001250553,0.0002571398,0.0001831491,0.002083419,0.0000154149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000234074,"about_ca_system_score_gemma":0.0002814447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001154655,"about_ca_topic_score_gemma":0.0003653829,"domain_scores_codex":[0.9943134,0.001886287,0.0009586905,0.001069443,0.0004945158,0.001277659],"domain_scores_gemma":[0.996381,0.002160193,0.0001576169,0.0005338516,0.0002943045,0.0004730297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00725902,0.002592782,0.008632176,0.0002750681,0.0002649243,0.00002510947,0.00104575,0.000004299974,0.7648611,0.0001843397,0.00004379781,0.2148116],"study_design_scores_gemma":[0.00945683,0.002421355,0.005730764,0.00005387166,0.0001241726,0.00002387508,0.0003051174,0.004661276,0.9631155,0.0007356408,0.01296944,0.0004021596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923799,0.001297435,0.0002409627,0.001068303,0.0006692328,0.004028452,0.00006021954,0.00006629055,0.000189187],"genre_scores_gemma":[0.9939184,0.001641024,0.001211677,0.000430558,0.0003610574,0.001330576,0.00004333608,0.00008129822,0.0009821046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2144094,"threshold_uncertainty_score":0.999836,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4210247789","doi":"10.1016/j.matt.2021.11.021","title":"Bioinspired microneedle patches: Biomimetic designs, fabrication, and biomedical applications","year":2022,"lang":"en","type":"article","venue":"Matter","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":147,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Nanotechnology; Biomimetic materials; Fabrication; Biomimetics; Computer science; Engineering; Materials science; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.08320986262775361,"gpt":0.3937986591481108,"spread":0.3105887965203572,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002664846,0.0001356973,0.000133442,0.0001236748,0.0004742918,0.00001214456,0.0002313562,0.00007940862,0.00771258],"category_scores_gemma":[0.000005715492,0.0001447573,0.00003618874,0.0002504959,0.0002714058,0.00005686433,0.0001562454,0.0003655764,0.000589596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007244095,"about_ca_system_score_gemma":0.00003104422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001173785,"about_ca_topic_score_gemma":5.400671e-7,"domain_scores_codex":[0.998798,0.0002358258,0.0002501985,0.0003038374,0.0001365646,0.0002755969],"domain_scores_gemma":[0.9994372,0.0001400964,0.00007031568,0.0001918943,0.00003102085,0.0001294828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003477039,0.002540469,0.1076244,0.0002754027,0.000454985,0.00004702448,0.003668554,0.0004490445,0.5109723,0.0006564326,0.2753189,0.09764475],"study_design_scores_gemma":[0.0009943752,0.00006530881,0.003777685,0.000002269932,0.00009876127,0.00003647988,0.0003351085,0.0005812412,0.007422766,0.00053186,0.9859134,0.0002407604],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7312427,0.00609186,0.2217279,0.02669693,0.002392384,0.003935816,0.001339601,0.0005370438,0.006035728],"genre_scores_gemma":[0.9810773,0.00008665097,0.00202227,0.01378659,0.0001270932,0.0009872896,0.0001709139,0.00003139906,0.001710515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7105945,"threshold_uncertainty_score":0.9931945,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2126324493","doi":"10.1002/adhm.201500357","title":"Dermal Patch with Integrated Flexible Heater for on Demand Drug Delivery","year":2015,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":145,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Victoria","funders":"National Institute of Dental and Craniofacial Research; National Institute of Biomedical Imaging and Bioengineering; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Drug delivery; Materials science; Nanotechnology; Microcarrier; Microfluidics; Controlled release; On demand; Layer (electronics); Biomedical engineering; Computer science; Chemistry; Engineering","retraction":null,"screen_n_in":null,"score":{"opus":0.1461178564983962,"gpt":0.4477241545369463,"spread":0.30160629803855,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008164471,0.0004649247,0.0006326164,0.0001340715,0.0003311364,0.00003684039,0.0003048459,0.0002838013,0.0002629321],"category_scores_gemma":[0.00005417112,0.0003824648,0.00006322826,0.0001819685,0.000192822,0.0003397121,0.00005613505,0.0004356404,0.000158642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003009964,"about_ca_system_score_gemma":0.0003009861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002167306,"about_ca_topic_score_gemma":0.0002134895,"domain_scores_codex":[0.9968294,0.0005744591,0.0006402736,0.0006421249,0.0002756082,0.001038161],"domain_scores_gemma":[0.9980603,0.0003260334,0.0002175746,0.0003487428,0.0004947367,0.0005526517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.1611075,0.003140926,0.01681973,0.004765939,0.001683897,0.0008456743,0.01163934,0.0470296,0.4342402,0.008704435,0.04347665,0.2665461],"study_design_scores_gemma":[0.008462923,0.001441499,0.000237212,0.0002039609,0.0001292672,0.00004294697,0.0006728398,0.0002462412,0.8276041,0.002028611,0.1582113,0.0007190244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847671,0.0007854713,0.003585346,0.004222205,0.002916161,0.002057738,0.001010909,0.0003350039,0.0003200121],"genre_scores_gemma":[0.9822892,0.0003237084,0.006240116,0.008776112,0.000337655,0.0006288509,0.000453876,0.00009951365,0.0008509684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.393364,"threshold_uncertainty_score":0.9998627,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2328918441","doi":"10.1021/mp300441c","title":"Effect of Chemical Permeation Enhancers on Stratum Corneum Barrier Lipid Organizational Structure and Interferon Alpha Permeability","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":138,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"Canadian Institutes of Health Research; University of Saskatchewan; U.S. Department of Energy","keywords":"Chemistry; Stratum corneum; Permeation; Chromatography; Organic chemistry; Biochemistry; Membrane","retraction":null,"screen_n_in":null,"score":{"opus":0.02029365774704917,"gpt":0.366703373565882,"spread":0.3464097158188328,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003296177,0.0003911288,0.000364327,0.00009884223,0.0001112049,0.00002584749,0.0002724863,0.0003591066,0.003325532],"category_scores_gemma":[0.0001534045,0.0003703918,0.00009336425,0.0002053044,0.0004757837,0.0001718815,0.0001059645,0.0009554047,0.00004752693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001403609,"about_ca_system_score_gemma":0.00006340625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004432612,"about_ca_topic_score_gemma":4.44129e-7,"domain_scores_codex":[0.9976254,0.0006404239,0.0004535082,0.0005083797,0.0003390015,0.0004332915],"domain_scores_gemma":[0.9987241,0.0003582429,0.0001581518,0.0002552744,0.0002197803,0.0002844237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006234295,0.0001505007,0.004233046,0.0002695004,0.0001978563,0.00001004639,0.00031622,0.00110446,0.97425,0.000208759,0.0002425021,0.01839372],"study_design_scores_gemma":[0.002142707,0.0005157089,0.0003439187,0.0000249647,0.0002468036,0.00001693899,0.00002656081,0.01565466,0.979283,0.0002137634,0.001226082,0.0003048541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958824,0.0003041272,0.001059003,0.0002351172,0.0007743056,0.0009696361,0.0001533291,0.00006444432,0.0005576733],"genre_scores_gemma":[0.9978237,0.0001107326,0.0001883873,0.001450933,0.0001254954,0.00004574331,0.0001261118,0.00005233838,0.00007654796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01808886,"threshold_uncertainty_score":0.9998748,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2005986992","doi":"10.1016/j.jphotobiol.2013.07.014","title":"Quercetin deformable liposome: Preparation and efficacy against ultraviolet B induced skin damages in vitro and in vivo","year":2013,"lang":"en","type":"article","venue":"Journal of Photochemistry and Photobiology B Biology","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":136,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute for Biological Sciences; National Research Council Canada","funders":"","keywords":"Liposome; HaCaT; In vivo; Chemistry; Reactive oxygen species; Quercetin; Viability assay; Malondialdehyde; Pharmacology; In vitro; Phosphatidylcholine; Biophysics; Oxidative stress; Biochemistry; Antioxidant; Biology; Membrane","retraction":null,"screen_n_in":null,"score":{"opus":0.03170004890680364,"gpt":0.3778946367980162,"spread":0.3461945878912125,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000672238,0.0002596661,0.0005170537,0.0001712708,0.00008430441,0.00001423808,0.0001669233,0.0006678592,0.0001843467],"category_scores_gemma":[0.0001110505,0.0002267822,0.00004319768,0.00011036,0.000462092,0.0001888052,0.00007606081,0.001081374,0.000002203059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005019597,"about_ca_system_score_gemma":0.00005803303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006679314,"about_ca_topic_score_gemma":0.00002101481,"domain_scores_codex":[0.9981604,0.0004041132,0.0006655041,0.0003156659,0.00004490089,0.0004093878],"domain_scores_gemma":[0.9988013,0.0005138022,0.0003375737,0.0001076854,0.00007074907,0.0001689099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001442931,0.0001892889,0.02504298,0.00006155832,0.00006525576,0.00002782538,0.0005571172,0.0000426365,0.9679115,0.000005567263,0.00006591706,0.004587416],"study_design_scores_gemma":[0.004352233,0.0003085984,0.009465748,0.00004940318,0.00003462274,0.0003278198,0.0003212252,0.0004814444,0.9814285,0.0003206916,0.002659717,0.0002499745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973525,0.001306994,0.00001202467,0.0001847208,0.0001916567,0.00049891,0.00004150045,0.000008594478,0.0004030839],"genre_scores_gemma":[0.9954194,0.003366803,0.0002018635,0.0007937166,0.00008059396,0.00005376322,0.0000244827,0.00001109754,0.00004832194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01557723,"threshold_uncertainty_score":0.9247909,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2721615787","doi":"10.2147/dddt.s102500","title":"Intranasal agomelatine solid lipid nanoparticles to enhance brain delivery: formulation, optimization and in vivo pharmacokinetics","year":2017,"lang":"en","type":"article","venue":"Drug Design Development and Therapy","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":135,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Bioavailability; Solid lipid nanoparticle; Pharmacokinetics; Pharmacology; Nasal administration; Drug delivery; In vivo; Chemistry; First pass effect; Zeta potential; Agomelatine; Chromatography; Drug; Nanoparticle; Materials science; Medicine; Nanotechnology; Antidepressant; Internal medicine; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.07019639001687886,"gpt":0.4005162602364778,"spread":0.330319870219599,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007072354,0.0002497183,0.0002395952,0.0001387458,0.0005829781,0.00007887814,0.0002213954,0.0001107012,0.0002584461],"category_scores_gemma":[0.00003443791,0.000249683,0.00001777592,0.00009113731,0.0001179846,0.0003586571,0.00007231608,0.0002275957,0.000008914158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004393012,"about_ca_system_score_gemma":0.0000609884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006865161,"about_ca_topic_score_gemma":0.00002249829,"domain_scores_codex":[0.9985166,0.0001866358,0.0003956399,0.0003665477,0.0001484793,0.000386146],"domain_scores_gemma":[0.9992173,0.0002348697,0.0001379011,0.0001587984,0.00007026305,0.0001808087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002873898,0.0004269849,0.01697546,0.00006086544,0.000271222,0.00004397641,0.0126047,0.09862194,0.4041522,0.0001566782,0.002179997,0.4616321],"study_design_scores_gemma":[0.003001829,0.00007226455,0.002778856,0.00003926786,0.00001897095,0.000004078534,0.0000705672,0.04373608,0.9000049,0.0001629809,0.04967356,0.0004367037],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9522374,0.000843804,0.04334461,0.002220308,0.000324623,0.0008215963,0.000008463549,0.00004836693,0.0001507992],"genre_scores_gemma":[0.9713541,0.003824066,0.02203179,0.00211721,0.00008809307,0.00008968424,0.000008869452,0.00002839236,0.0004578372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4958527,"threshold_uncertainty_score":0.9999955,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2073722144","doi":"10.1159/000211345","title":"Study of the Stratum corneum Barrier Function by Transepidermal Water Loss Measurements: Comparison between Two Commercial Instruments: Evaporimeter <sup>®</sup> and Tewameter <sup>®</sup>","year":2009,"lang":"en","type":"article","venue":"Skin Pharmacology","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":130,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre for Movement Disorders","funders":"","keywords":"Transepidermal water loss; Stratum corneum; Chemistry; Relative humidity; Reproducibility; Skin barrier; Analytical Chemistry (journal); Chromatography; Dermatology; Medicine; Pathology; Thermodynamics","retraction":null,"screen_n_in":null,"score":{"opus":0.0931047874885305,"gpt":0.4024069380248515,"spread":0.309302150536321,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001485023,0.0008625452,0.001186368,0.0002628423,0.0008124485,0.00004337853,0.0009418822,0.0005772418,0.002303584],"category_scores_gemma":[0.00002917192,0.0006721757,0.0002807043,0.0003635963,0.0008780885,0.0005622403,0.0002266272,0.002230108,0.00006379897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002059585,"about_ca_system_score_gemma":0.00009453647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006720824,"about_ca_topic_score_gemma":0.00001745945,"domain_scores_codex":[0.9919114,0.003213741,0.001653416,0.001068079,0.0007501251,0.001403267],"domain_scores_gemma":[0.9979857,0.0004135703,0.0003971786,0.0005026386,0.0002603804,0.0004405999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008934462,0.01285384,0.5989195,0.0002555658,0.007323385,0.000101783,0.02611639,0.03893961,0.1541603,0.00004433459,0.0442393,0.1081116],"study_design_scores_gemma":[0.08461737,0.009617673,0.06783886,0.0001013409,0.0131843,0.0001473547,0.005325638,0.01485746,0.6782822,0.001067259,0.1214936,0.003466972],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926769,0.0003744929,0.0003840662,0.001124006,0.001703842,0.0026006,0.0003272784,0.0001087377,0.0007000856],"genre_scores_gemma":[0.9922303,0.00006814006,0.0000702485,0.00635126,0.0006237295,0.00015384,0.0001377777,0.00007571821,0.000289011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5310806,"threshold_uncertainty_score":0.9995729,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2099202432","doi":"10.1046/j.1365-4362.2002.01555.x","title":"Correlation between pH and irritant effect of cleansers marketed for dry skin","year":2002,"lang":"en","type":"article","venue":"International Journal of Dermatology","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":125,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Irritation; Skin irritation; Dry skin; Cleanser; Medicine; Erythema; Population; Dermatology; Cosmetics; Dove; Toxicology; Biology; Environmental health","retraction":null,"screen_n_in":null,"score":{"opus":0.04923655542895746,"gpt":0.402569231851293,"spread":0.3533326764223356,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002466883,0.0001320204,0.0003441512,0.0002282023,0.00005077217,0.000006619732,0.0002298675,0.0001971337,0.0003309818],"category_scores_gemma":[0.0001842901,0.0001203392,0.0001240659,0.00005594432,0.0001910488,0.000221461,0.00003272974,0.0003755865,0.000007215251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004747145,"about_ca_system_score_gemma":0.00001513915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001530049,"about_ca_topic_score_gemma":0.000001382656,"domain_scores_codex":[0.9985407,0.0003400493,0.0006392009,0.0001157514,0.0001902317,0.0001740658],"domain_scores_gemma":[0.9973626,0.001728545,0.0004872073,0.00005512269,0.0002791864,0.00008735781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006438244,0.0004982312,0.6977911,0.0003699858,0.004000368,0.001264287,0.001635691,0.001795628,0.01178184,0.002067791,0.006248728,0.2661081],"study_design_scores_gemma":[0.06886097,0.004135684,0.07307091,0.0005298636,0.003194983,0.02241288,0.0005274246,0.1901572,0.2937426,0.007324839,0.3345055,0.001537146],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676175,0.001258486,0.02403684,0.003213748,0.002577042,0.0003092606,0.00009995724,0.00001342651,0.0008737494],"genre_scores_gemma":[0.9983009,0.0004951566,0.0006693371,0.0002217198,0.0001791945,0.00000631253,0.00001174625,0.00001332096,0.0001023529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6247202,"threshold_uncertainty_score":0.4907292,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3201854675","doi":"10.1016/j.jconrel.2021.10.001","title":"Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of cutaneous fungal infections","year":2021,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":122,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"China Scholarship Council; Queen's University; Queen's University Belfast","keywords":"Amphotericin B; Candida albicans; Bioavailability; Dosage form; Pharmacology; Drug delivery; Drug; In vivo; Chemistry; Microbiology; Medicine; Biology; Antifungal; Organic chemistry; Biotechnology","retraction":null,"screen_n_in":null,"score":{"opus":0.02646592893394397,"gpt":0.3410932243156525,"spread":0.3146272953817085,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001802657,0.0002410437,0.0007635939,0.0001123449,0.0002189637,0.00002502768,0.00008337418,0.0001451894,0.00006178845],"category_scores_gemma":[0.0001395268,0.0001866736,0.0002960093,0.0001044578,0.0001973768,0.0001366045,0.00001420472,0.0001975384,4.125245e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001262769,"about_ca_system_score_gemma":0.0003143581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000747813,"about_ca_topic_score_gemma":0.00001647493,"domain_scores_codex":[0.9983435,0.0002317555,0.0007263139,0.0002008502,0.0001267086,0.0003709226],"domain_scores_gemma":[0.9975452,0.0009582987,0.0005214458,0.0001011387,0.0006657341,0.0002081111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0487869,0.001645208,0.000335932,0.0001485739,0.001697554,0.0003876729,0.0007574399,0.01350472,0.9220681,0.00003553758,0.00007772801,0.01055467],"study_design_scores_gemma":[0.07101777,0.003904791,0.00007745401,0.00006224307,0.00244079,0.0007966224,0.001508962,0.01284435,0.9054965,0.000121743,0.001486366,0.0002424205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9097409,0.002771929,0.08539354,0.0006170705,0.0003304329,0.0009962252,0.0001252809,0.00001169328,0.00001292338],"genre_scores_gemma":[0.9958004,0.0009800384,0.002516375,0.0002245518,0.0002199256,0.00007294265,0.00001302701,0.00002812478,0.0001446254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08605948,"threshold_uncertainty_score":0.7612329,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1971208013","doi":"10.1038/sj.gt.3301886","title":"Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines","year":2003,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":118,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"","keywords":"Immunization; Genetic enhancement; Gene delivery; Virology; Medicine; Adenoviridae; Immunology; Biology; Antibody; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.09270139581148576,"gpt":0.4009540400636902,"spread":0.3082526442522044,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001018492,0.0001967383,0.0002538891,0.0001065626,0.0001951372,0.00001090299,0.000293865,0.0002063634,0.0002504909],"category_scores_gemma":[0.0001349702,0.0001945026,0.00007780663,0.0001820405,0.00008017747,0.0001047284,0.00003153779,0.0002012638,0.000001294194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003215664,"about_ca_system_score_gemma":0.00007837683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001524075,"about_ca_topic_score_gemma":0.00001006826,"domain_scores_codex":[0.9985416,0.0004484899,0.0003790279,0.0002609439,0.000109658,0.0002603116],"domain_scores_gemma":[0.998525,0.0006765562,0.0001541443,0.0003576592,0.00021376,0.00007284534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001297233,0.0003591371,0.001180845,0.00007274847,0.0002069259,0.000002068348,0.0004288765,0.005395335,0.9202875,0.000809296,0.0003960193,0.06956398],"study_design_scores_gemma":[0.0108355,0.0004727541,0.0002119712,0.00001187923,0.00009885518,0.00001206866,0.000122966,0.01853426,0.9075769,0.002740347,0.05908596,0.0002965798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1687252,0.005187948,0.8242947,0.0005900027,0.000359056,0.0006594032,0.00008241434,0.00003917555,0.00006208471],"genre_scores_gemma":[0.5554391,0.002941837,0.4317204,0.008912428,0.0003371328,0.0001801962,0.0001323896,0.00008186563,0.0002546762],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.3925743,"threshold_uncertainty_score":0.7931587,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4384339055","doi":"10.3390/pharmaceutics15071944","title":"Lipid-Based Delivery Systems for Flavonoids and Flavonolignans: Liposomes, Nanoemulsions, and Solid Lipid Nanoparticles","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":114,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"University of Zabol","keywords":"Solid lipid nanoparticle; Bioavailability; Nanocarriers; Liposome; Drug delivery; Chemistry; Nanotechnology; Pharmacology; Materials science; Biochemistry; Medicine; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.2780077435241874,"gpt":0.4994662847388794,"spread":0.2214585412146919,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001452626,0.001349781,0.002580017,0.000588488,0.0008804801,0.0001725422,0.0007265516,0.001293977,0.00008357213],"category_scores_gemma":[0.0002114363,0.001296536,0.000491466,0.0005815518,0.0006905309,0.0002844236,0.0003983679,0.001783792,0.0002005479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002695083,"about_ca_system_score_gemma":0.0004973483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001686741,"about_ca_topic_score_gemma":0.00000914825,"domain_scores_codex":[0.9937544,0.001112434,0.001802644,0.001384724,0.0004018968,0.001543899],"domain_scores_gemma":[0.9938146,0.003776728,0.0007231231,0.0005667534,0.0002468352,0.0008719595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003250014,0.0004710082,0.00003681309,0.06558452,0.002157851,0.0001078679,0.0002689041,0.001002054,0.001537205,0.0003745251,0.00652457,0.9216097],"study_design_scores_gemma":[0.002688778,0.0001891295,7.869714e-7,0.004082701,0.005836982,0.00006450657,0.00008552502,0.01980671,0.001660659,0.00004503734,0.9642569,0.001282218],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008496277,0.9858077,0.0002962976,0.000168827,0.005154926,0.004767082,0.00233812,0.0005418399,0.00007558801],"genre_scores_gemma":[0.0007001415,0.992941,0.0004285519,0.001048576,0.001429603,0.001706604,0.0004315748,0.0003730831,0.0009408453],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9577324,"threshold_uncertainty_score":0.9999253,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2998641978","doi":"10.1016/j.actbio.2019.12.037","title":"Construction of a core-shell microneedle system to achieve targeted co-delivery of checkpoint inhibitors for melanoma immunotherapy","year":2020,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":113,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"Traditional Chinese Medicine Bureau of Guangdong Province; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Materials science; Immunotherapy; Melanoma; Cancer research; Core (optical fiber); Nanotechnology; Medicine; Cancer; Internal medicine; Composite material","retraction":null,"screen_n_in":null,"score":{"opus":0.07394710359837035,"gpt":0.3732128914485474,"spread":0.299265787850177,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002932682,0.0002613763,0.0005217253,0.0001043359,0.00009134295,0.00001020099,0.000301928,0.0002960244,0.0003222155],"category_scores_gemma":[0.00002735092,0.0002643284,0.0001512892,0.0001987183,0.0002476886,0.0001117489,0.00005624936,0.0001097133,0.00003317996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007717512,"about_ca_system_score_gemma":0.00006605171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005331889,"about_ca_topic_score_gemma":0.000001405414,"domain_scores_codex":[0.9981779,0.0001655193,0.0008415322,0.0003333993,0.0001546679,0.0003269867],"domain_scores_gemma":[0.9989391,0.0001141264,0.0004197631,0.0001917068,0.000181145,0.0001541438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00665537,0.0001351542,0.0004403291,0.0006584153,0.0003661341,0.000004662811,0.001481284,0.00004194383,0.9842504,0.000154336,0.004868839,0.0009431795],"study_design_scores_gemma":[0.002679531,0.0008499153,0.0001188775,0.00005503698,0.0001073956,0.000007507167,0.0005997609,0.0003982778,0.9666615,0.00001977842,0.02826444,0.000237993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869789,0.0001508922,0.0008022074,0.0002926179,0.008649199,0.001109419,0.001830235,0.00009300655,0.0000935335],"genre_scores_gemma":[0.9950584,0.00005569505,0.003564028,0.0003747775,0.0006490946,0.00006808589,0.0001681829,0.00004247983,0.00001928877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0233956,"threshold_uncertainty_score":0.9999809,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2095600570","doi":"10.1016/j.ijpharm.2007.07.047","title":"Linker-based lecithin microemulsions for transdermal delivery of lidocaine","year":2007,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":112,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Transdermal; Linker; Microemulsion; Chemistry; Lecithin; Permeation; Isopropyl myristate; Chromatography; Isopropyl alcohol; Organic chemistry; Pulmonary surfactant; Membrane; Pharmacology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.135148223144739,"gpt":0.4975492730475192,"spread":0.3624010499027801,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001852773,0.0002660818,0.0003959821,0.0005096261,0.0001098687,0.00001647896,0.000925744,0.0002611017,0.0005364622],"category_scores_gemma":[0.0001651834,0.0002631047,0.0004411657,0.0001858352,0.0002916867,0.000266762,0.00004707548,0.00098038,0.00001010389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001871414,"about_ca_system_score_gemma":0.0002708451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003702808,"about_ca_topic_score_gemma":0.000007395352,"domain_scores_codex":[0.9971385,0.000154913,0.001428464,0.0002004843,0.000622889,0.0004547196],"domain_scores_gemma":[0.99545,0.001524702,0.0008317426,0.0001237654,0.001771694,0.0002981076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01006324,0.002105848,0.00435113,0.0001549844,0.0018556,0.000613499,0.001023984,0.03412826,0.8226352,0.0007484856,0.001762433,0.1205573],"study_design_scores_gemma":[0.008183825,0.0002617336,0.0002852439,0.00008032755,0.000402945,0.0001650036,0.0001458971,0.009935864,0.7582688,0.0003036179,0.2217354,0.0002314354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6841596,0.002143301,0.299864,0.00281855,0.009163854,0.0005653866,0.0005327209,0.00003853365,0.000714028],"genre_scores_gemma":[0.979484,0.0006765104,0.01461958,0.003942438,0.001028186,0.000005603813,0.00003619652,0.00004164929,0.0001658879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2953243,"threshold_uncertainty_score":0.9999821,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3004841311","doi":"10.2147/dddt.s232325","title":"&lt;p&gt;Potential Use of Microbial Surfactant in Microemulsion Drug Delivery System: A Systematic Review&lt;/p&gt;","year":2020,"lang":"en","type":"review","venue":"Drug Design Development and Therapy","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":111,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Kerman University of Medical Sciences","keywords":"Microemulsion; Pulmonary surfactant; Bioavailability; Lipopeptide; Drug; Chemistry; Pharmacology; Medicine; Biology; Biochemistry; Bacteria","retraction":null,"screen_n_in":null,"score":{"opus":0.1128185815740917,"gpt":0.3610691502098701,"spread":0.2482505686357784,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.002421347,0.001295658,0.004850464,0.000495371,0.0002754915,0.00006469248,0.0008294475,0.0006186453,0.0001353],"category_scores_gemma":[0.00006234935,0.001079284,0.0005450774,0.0006824374,0.0002277998,0.0002964576,0.0002091826,0.001139968,0.0001300057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000486602,"about_ca_system_score_gemma":0.0007980093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006860921,"about_ca_topic_score_gemma":0.000009760663,"domain_scores_codex":[0.9902357,0.003981781,0.003266413,0.001081887,0.0005338143,0.0009003835],"domain_scores_gemma":[0.9964197,0.00104909,0.001514301,0.000474509,0.000205873,0.0003364942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005950245,0.0004968682,0.000005360205,0.793826,0.002319062,0.0006894182,0.001607142,0.0000357947,0.003784322,0.00004817498,0.003382597,0.1932102],"study_design_scores_gemma":[0.001904308,0.00005143609,0.000001526195,0.2209034,0.002409915,0.0001360313,0.00003144613,0.0001573778,0.002250114,0.000005191051,0.7709602,0.001189082],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001003359,0.9890236,0.0006296886,0.00005198893,0.001191276,0.007814979,0.0001409629,0.000117376,0.00002677924],"genre_scores_gemma":[0.0006441013,0.9947141,0.002437594,0.000567782,0.00009452775,0.0006074188,0.0002640257,0.0001561959,0.0005142221],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7675776,"threshold_uncertainty_score":0.9999795,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3170463987","doi":"10.1016/j.msec.2021.112226","title":"Hydrogel-forming microneedles for rapid and efficient skin deposition of controlled release tip-implants","year":2021,"lang":"en","type":"article","venue":"Materials Science and Engineering C","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":105,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"China Scholarship Council; Queen's University Belfast; Queen's University; Wellcome Trust","keywords":"PLGA; Materials science; Amphotericin B; Biomedical engineering; Ex vivo; Dissolution; Drug delivery; In vivo; Controlled release; Nanotechnology; Antifungal; Chemical engineering; Nanoparticle; Medicine; Dermatology","retraction":null,"screen_n_in":null,"score":{"opus":0.03012403733211406,"gpt":0.3334086552871863,"spread":0.3032846179550723,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006444445,0.0001049081,0.0002251682,0.00007875673,0.0001571418,0.00002673532,0.00007384388,0.00006127526,0.00003599492],"category_scores_gemma":[0.0001042906,0.00009924609,0.00001967987,0.0001021241,0.0001647049,0.0000917283,0.00004609726,0.00005699253,0.000001281013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002287404,"about_ca_system_score_gemma":0.00004327634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003734671,"about_ca_topic_score_gemma":4.515458e-7,"domain_scores_codex":[0.9991869,0.00002203133,0.0002300108,0.0002005943,0.0001048755,0.0002556174],"domain_scores_gemma":[0.9995623,0.0001388123,0.00005533356,0.00006947207,0.00008840764,0.00008571021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002073401,0.00003851414,0.00002249057,0.0001709396,0.00002170725,0.000007649121,0.000228285,0.0051036,0.9910318,0.0002196471,0.000009701636,0.002938286],"study_design_scores_gemma":[0.002062289,0.00004375824,0.0002203619,0.00003893382,0.00005167659,0.0000517399,0.00006525224,0.02510718,0.9717927,0.00001826814,0.0004403252,0.0001075193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948776,0.0008129426,0.003282207,0.00004307926,0.0005779355,0.0002724178,0.00007627077,0.0000213886,0.0000361282],"genre_scores_gemma":[0.9977754,0.0002551817,0.001751086,0.0001086989,0.0000451142,0.00003253317,0.000008827078,0.00000813821,0.00001495909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02000357,"threshold_uncertainty_score":0.4047138,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2000442076","doi":"10.1016/j.bpc.2010.03.008","title":"The microstructure of the stratum corneum lipid barrier: Mid-infrared spectroscopic studies of hydrated ceramide:palmitic acid:cholesterol model systems","year":2010,"lang":"en","type":"article","venue":"Biophysical Chemistry","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":104,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Research Council Canada; H2020 European Research Council; Deutsche Forschungsgemeinschaft","keywords":"Stratum corneum; Ceramide; Chemistry; Palmitic acid; Orthorhombic crystal system; Sphingosine; Infrared spectroscopy; Crystallography; Fatty acid; Organic chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.04151737391806389,"gpt":0.3668464595447323,"spread":0.3253290856266685,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001598463,0.0003182302,0.0004318406,0.00001252391,0.0003159464,0.00002064998,0.00076942,0.0003649284,0.00004697031],"category_scores_gemma":[0.0001179431,0.0002055209,0.0001872097,0.0001782395,0.001622493,0.00007035537,0.0001561472,0.001425346,0.000005824675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004648907,"about_ca_system_score_gemma":0.00014277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003368275,"about_ca_topic_score_gemma":0.000001465673,"domain_scores_codex":[0.9982759,0.0001234705,0.0005590612,0.0003398789,0.0002689032,0.0004327382],"domain_scores_gemma":[0.998432,0.0002834633,0.0003440071,0.0005889079,0.0002252693,0.0001263511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001442561,0.0001336601,0.0005492734,0.0004334648,0.0002673479,0.000002390114,0.0002510394,0.001304435,0.9963016,0.000136032,0.0004077331,0.00006874871],"study_design_scores_gemma":[0.00080647,0.00003111608,0.0005234138,0.00005062005,0.0001751935,0.000007412536,0.0002622209,0.008516138,0.9881756,0.0004980248,0.0007680725,0.0001857546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995952,0.000681671,0.00002611052,0.0001721643,0.001686341,0.0003730047,0.0002690864,0.00003831946,0.0008013088],"genre_scores_gemma":[0.9977419,0.0001468353,0.00003707585,0.0001263515,0.000343361,0.00004055349,0.00001385734,0.00002753472,0.001522566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008126056,"threshold_uncertainty_score":0.8380899,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1965769799","doi":"10.1016/j.jconrel.2008.02.014","title":"Molecular interactions, internal structure and drug release kinetics of rationally developed polymer–lipid hybrid nanoparticles","year":2008,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":101,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Differential scanning calorimetry; Polymer; Chemical engineering; Chemistry; Solid lipid nanoparticle; Nanoparticle; Materials science; Drug delivery; Organic chemistry; Nanotechnology","retraction":null,"screen_n_in":null,"score":{"opus":0.02851069812658543,"gpt":0.3490466854779986,"spread":0.3205359873514131,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002817398,0.0002310408,0.0005970155,0.0002201067,0.0001242486,0.00001223082,0.0002391356,0.00008360967,0.0004089742],"category_scores_gemma":[0.0003712107,0.0001943213,0.0002009565,0.0001122604,0.000286669,0.0002560792,0.00004699687,0.0008006691,0.000004022321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006016966,"about_ca_system_score_gemma":0.0002034225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004766943,"about_ca_topic_score_gemma":0.000004217225,"domain_scores_codex":[0.9976189,0.000500133,0.001113734,0.0001667642,0.0003473372,0.0002531166],"domain_scores_gemma":[0.9977708,0.0004526527,0.00085585,0.0001247263,0.0005052612,0.0002906842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01487766,0.000629465,0.002494493,0.00005201873,0.0008875976,0.001107421,0.0004847829,0.009044442,0.9586693,0.0003016769,0.002195301,0.00925583],"study_design_scores_gemma":[0.02413478,0.0003335277,0.001123684,0.00008385353,0.0006132963,0.001886876,0.0001065723,0.004368624,0.9551212,0.0003127241,0.01163819,0.0002766435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885524,0.005154409,0.003526673,0.001350822,0.0009064485,0.0002767893,0.00005414402,0.00001170369,0.000166612],"genre_scores_gemma":[0.9957702,0.001252796,0.000843496,0.001448769,0.0002363764,0.000005526669,0.000005836629,0.00002342015,0.000413575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009442892,"threshold_uncertainty_score":0.7924194,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2515414172","doi":"10.1007/s40262-016-0442-z","title":"Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence","year":2016,"lang":"en","type":"article","venue":"Clinical Pharmacokinetics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":100,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"U.S. Food and Drug Administration","keywords":"Bioequivalence; Pharmacokinetics; Medicine; Pharmacology","retraction":null,"screen_n_in":null,"score":{"opus":0.283421452958704,"gpt":0.5430172333162642,"spread":0.2595957803575601,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002707095,0.0007529261,0.000920901,0.0001984551,0.0004079526,0.0001038635,0.003356701,0.000584482,0.009685177],"category_scores_gemma":[0.0008000975,0.0005621385,0.0003709039,0.0005750509,0.0009200365,0.0004340203,0.002256843,0.001501717,0.004908957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000177938,"about_ca_system_score_gemma":0.0002618549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000134615,"about_ca_topic_score_gemma":0.000001713731,"domain_scores_codex":[0.9923316,0.001925746,0.001857872,0.001711182,0.0006987896,0.001474789],"domain_scores_gemma":[0.9951775,0.001601005,0.000315046,0.0008452741,0.0004192769,0.001641897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003995488,0.003504381,0.005052438,0.0001125122,0.000479086,0.0001876591,0.0002646781,0.002726512,0.2289437,0.0004580904,0.0706243,0.6836511],"study_design_scores_gemma":[0.01569582,0.0009412064,0.001858943,0.0001180633,0.0008370486,0.0001081427,0.00003617546,0.01512684,0.08406031,0.0006574951,0.8792744,0.001285547],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8088328,0.001448343,0.0650649,0.01801167,0.01298632,0.006864345,0.0005703497,0.0006616685,0.08555964],"genre_scores_gemma":[0.9200922,0.004738332,0.0188736,0.04182834,0.002151931,0.000404467,0.00004483141,0.0001683408,0.01169796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8086501,"threshold_uncertainty_score":0.999683,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2765869733","doi":"10.1016/j.ijpharm.2017.10.035","title":"Novel dissolving microneedles for enhanced transdermal delivery of levonorgestrel: In vitro and in vivo characterization","year":2017,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":100,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Science Foundation of Anhui Province; Sun Yat-sen University; National Natural Science Foundation of China","keywords":"Transdermal; Bioavailability; Drug delivery; Pharmacology; Pharmacokinetics; Drug; Cmax; In vivo; Levonorgestrel; Chitosan; Dissolution; Chemistry; Materials science; Medicine; Nanotechnology; Organic chemistry; Population","retraction":null,"screen_n_in":null,"score":{"opus":0.0909954075081093,"gpt":0.4396270744319242,"spread":0.3486316669238149,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005801218,0.0001776586,0.00032548,0.0003242112,0.00008659967,0.00003634214,0.0006000482,0.0001474051,0.00006656151],"category_scores_gemma":[0.0001168947,0.0001903597,0.0001019836,0.00004691881,0.0002136218,0.0006398761,0.00007036226,0.0005057938,5.830847e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001172346,"about_ca_system_score_gemma":0.00009310278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001253305,"about_ca_topic_score_gemma":0.00002143759,"domain_scores_codex":[0.9984426,0.00007386781,0.0008236946,0.0001707222,0.0002329698,0.0002561469],"domain_scores_gemma":[0.9983818,0.000301185,0.0007706417,0.00009728156,0.0003527123,0.00009637042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003484275,0.0004708049,0.008746813,0.0000692652,0.0001863953,0.00003986161,0.0008899714,0.001380626,0.9566695,0.00004559522,0.000004796985,0.02801207],"study_design_scores_gemma":[0.007133683,0.00004613938,0.01077581,0.0001274245,0.00008324456,0.00005137463,0.0001166652,0.009140178,0.9687293,0.00006686242,0.00356515,0.0001642061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819129,0.0003245447,0.01438667,0.0007999859,0.00182783,0.0002677621,0.0003763092,0.000005127111,0.00009885968],"genre_scores_gemma":[0.9950438,0.002257849,0.002024832,0.000335998,0.0002381245,0.00001010692,0.00001722648,0.00002189226,0.00005016376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02784786,"threshold_uncertainty_score":0.7762645,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W284264172","doi":"10.1016/j.ejpb.2015.04.028","title":"Optimization of controlled release nanoparticle formulation of verapamil hydrochloride using artificial neural networks with genetic algorithm and response surface methodology","year":2015,"lang":"en","type":"article","venue":"European Journal of Pharmaceutics and Biopharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":99,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Response surface methodology; Artificial neural network; Central composite design; Biological system; Materials science; Particle size; Nanoparticle; Particle swarm optimization; Mathematics; Computer science; Algorithm; Chemistry; Chromatography; Chemical engineering; Nanotechnology; Machine learning; Engineering","retraction":null,"screen_n_in":null,"score":{"opus":0.2087789203769396,"gpt":0.4196622517784016,"spread":0.2108833314014619,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004621719,0.0003319445,0.0007264412,0.0002181936,0.0001423167,0.00002384194,0.0002278984,0.0001167244,0.00002703234],"category_scores_gemma":[0.0001894111,0.0002837874,0.0001078621,0.0003423285,0.0005070607,0.0002572019,0.0001084159,0.0007033041,5.218089e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006423934,"about_ca_system_score_gemma":0.0001405918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003321366,"about_ca_topic_score_gemma":3.494114e-7,"domain_scores_codex":[0.9943178,0.003238087,0.001392442,0.00026032,0.0003773652,0.0004139547],"domain_scores_gemma":[0.99652,0.0008135581,0.001285727,0.0001472123,0.0007299255,0.0005035892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.02551659,0.0002510551,0.001213644,0.0000568453,0.0003874903,0.0001973828,0.000697805,0.7736611,0.1787805,0.00002190023,0.000006269416,0.01920939],"study_design_scores_gemma":[0.01353544,0.0009920074,0.0001720356,0.00003788398,0.001136284,0.0003559107,0.0003157148,0.8293149,0.1534319,0.00002963016,0.0004411112,0.0002371195],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8099682,0.00442523,0.1844139,0.0001334155,0.0006212718,0.0003727168,0.00003166388,0.00001365373,0.00001996051],"genre_scores_gemma":[0.9272076,0.002114288,0.07010455,0.000321869,0.000186066,9.452325e-7,0.000003861299,0.00005160847,0.000009235703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1172393,"threshold_uncertainty_score":0.9999614,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2641793440","doi":"10.1016/j.jconrel.2017.06.016","title":"Biocompatible polymer microneedle for topical/dermal delivery of tranexamic acid","year":2017,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":98,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Biocompatible material; Tranexamic acid; Stratum corneum; Drug delivery; Chemistry; Bioadhesive; Methacrylic acid; Polymer; Biomedical engineering; Surgery; Medicine; Copolymer; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.08305605558930772,"gpt":0.4219628474222809,"spread":0.3389067918329731,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006444037,0.0002196134,0.0008581101,0.0001643287,0.0003558997,0.0000262491,0.0006421775,0.0002400048,0.0004226285],"category_scores_gemma":[0.0002130949,0.0001799147,0.0005572256,0.00003750349,0.0003075903,0.0003083224,0.00003694217,0.0005985275,0.00001050719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004530982,"about_ca_system_score_gemma":0.0001940846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001002773,"about_ca_topic_score_gemma":0.000004194711,"domain_scores_codex":[0.9980353,0.0002229166,0.000988756,0.0001597609,0.0002230747,0.0003701911],"domain_scores_gemma":[0.9973065,0.0005218219,0.001264001,0.0002831623,0.0003863773,0.000238115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.044749,0.001579394,0.003229663,0.000268181,0.002281531,0.0002067243,0.0004801051,0.001144761,0.8671573,0.0006518866,0.003317568,0.07493386],"study_design_scores_gemma":[0.1080031,0.001460103,0.001742442,0.0001614505,0.001897604,0.0001453855,0.0001985897,0.005936643,0.8473016,0.000501421,0.0321904,0.0004611988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777401,0.009457971,0.006904667,0.001645734,0.002062787,0.0008963071,0.00009309141,0.00001263163,0.001186706],"genre_scores_gemma":[0.995997,0.0009305373,0.0008168424,0.0007765358,0.0004776682,0.00002205272,0.000003229998,0.00002346667,0.000952708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07447267,"threshold_uncertainty_score":0.7336708,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4297989875","doi":"10.1007/s12032-022-01836-3","title":"RETRACTED ARTICLE: Niosomes: a novel targeted drug delivery system for cancer","year":2022,"lang":"en","type":"review","venue":"Medical Oncology","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":97,"is_retracted":true,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Niosome; Nanocarriers; Drug delivery; Drug; Nanotechnology; Pharmacology; Targeted drug delivery; Medicine; Vesicle; Materials science; Chemistry","retraction":{"nature":"Retraction","openalex_flagged":true},"screen_n_in":null,"score":{"opus":0.2040673654015406,"gpt":0.5081526482652872,"spread":0.3040852828637466,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.003020783,0.0008383506,0.0031793,0.0003430072,0.0005809185,0.00001443102,0.001439448,0.002972118,0.02234994],"category_scores_gemma":[0.000805949,0.0007490328,0.0008386831,0.0006999215,0.0005940104,0.0001148108,0.0004143128,0.006355112,0.0002188874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002934552,"about_ca_system_score_gemma":0.00420874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007343951,"about_ca_topic_score_gemma":0.000121122,"domain_scores_codex":[0.9925371,0.002034981,0.001930937,0.001127445,0.0008728796,0.001496684],"domain_scores_gemma":[0.9908674,0.006601525,0.0009123229,0.0004644514,0.0001652188,0.0009890827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003113355,0.001053327,0.000006135459,0.01381305,0.001542494,0.0005408925,0.0002127487,0.00003008057,0.00002174999,0.0002606382,0.02096347,0.9612441],"study_design_scores_gemma":[0.003106233,0.0002615293,0.000001213659,0.001438407,0.003332844,0.0002718131,0.000170532,0.001211616,0.00002437192,0.00001400387,0.9894698,0.0006976869],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008173769,0.9773741,0.0008023033,0.0007271373,0.01379752,0.003161285,0.002063188,0.0003678797,0.0016249],"genre_scores_gemma":[0.00009170704,0.9857553,0.0004647552,0.003333699,0.001973747,0.006067725,0.0008742595,0.0001766433,0.001262128],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9685063,"threshold_uncertainty_score":0.999496,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2299531285","doi":"10.1016/j.ejpb.2016.03.009","title":"Hydrogel-forming microneedle arrays: Potential for use in minimally-invasive lithium monitoring","year":2016,"lang":"en","type":"article","venue":"European Journal of Pharmaceutics and Biopharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":97,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; Medical Research Council; Queen's University Belfast; Queen's University; Henry Smith Charity; Action Medical Research","keywords":"Lithium (medication); In vivo; Chemistry; Lithium carbonate; In vitro; Extraction (chemistry); Hydrolysis; Aqueous solution; Chromatography; Biomedical engineering; Medicine; Biochemistry; Internal medicine; Biology; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.1196421359275942,"gpt":0.390408996210671,"spread":0.2707668602830768,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002773622,0.0005452005,0.0005937979,0.0004879349,0.0002830783,0.00008373959,0.0006209933,0.0001797423,0.0001012015],"category_scores_gemma":[0.0002474116,0.0004333163,0.0002919674,0.0002785684,0.0004427307,0.0007699981,0.0002084471,0.001106523,0.00002744985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002051787,"about_ca_system_score_gemma":0.000147863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001659149,"about_ca_topic_score_gemma":0.000001760092,"domain_scores_codex":[0.9959317,0.0006902955,0.001518929,0.0004806524,0.0003859152,0.0009924864],"domain_scores_gemma":[0.9967926,0.001073754,0.000808448,0.000213908,0.0004550747,0.0006561866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002352494,0.0004351981,0.01406701,0.0002082056,0.0004344544,0.001056273,0.0006954776,0.000854401,0.8879846,0.00004458719,0.0003555942,0.09151172],"study_design_scores_gemma":[0.01573598,0.0005339861,0.001200838,0.0004255146,0.0007092383,0.0004999295,0.0004547884,0.00264547,0.7998641,0.0001235956,0.1770361,0.0007704833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814975,0.004242575,0.008634374,0.0008310996,0.003669653,0.0006482027,0.0002112662,0.00004753693,0.0002178142],"genre_scores_gemma":[0.9710151,0.01722575,0.008901306,0.001044503,0.001273649,0.000009571345,0.000005005345,0.0001203929,0.0004047029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1766805,"threshold_uncertainty_score":0.9998119,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2472243521","doi":"10.1038/srep29075","title":"Integrated hollow microneedle-optofluidic biosensor for therapeutic drug monitoring in sub-nanoliter volumes","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":95,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Paul Scherrer Institut; University of British Columbia; Canada Research Chairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Analyte; Biomedical engineering; Biosensor; Therapeutic drug monitoring; Point of care; Materials science; Detection limit; Point-of-care testing; Absorbance; Chromatography; Drug detection; Nanotechnology; Drug; Chemistry; Medicine; Pharmacology","retraction":null,"screen_n_in":null,"score":{"opus":0.07539780759911369,"gpt":0.384766774435421,"spread":0.3093689668363073,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001827756,0.0003066036,0.0003222623,0.0003662136,0.0003511563,0.00008254278,0.0002798995,0.0002185553,0.0002544765],"category_scores_gemma":[0.000105586,0.0002281002,0.0001650628,0.0004801729,0.0005961186,0.0003510046,0.00006189376,0.0003154442,0.0001198458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002237317,"about_ca_system_score_gemma":0.0001579384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001196527,"about_ca_topic_score_gemma":0.0000136914,"domain_scores_codex":[0.9969361,0.0002251343,0.0007889205,0.000945643,0.0002787845,0.0008253902],"domain_scores_gemma":[0.9984689,0.0003185515,0.0002460094,0.0005528563,0.0002315319,0.0001821017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001455803,0.0002108209,0.06338244,0.00004039894,0.00007463235,0.0001893915,0.0005276568,0.00002642049,0.8845503,0.00001944465,0.006407943,0.04442502],"study_design_scores_gemma":[0.0009334275,0.00002534651,0.001527229,0.00009204862,0.00005183739,0.00004936738,0.0001123277,0.00008536602,0.7534769,0.001067923,0.2422973,0.0002809589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744574,0.002527002,0.001183226,0.0005421627,0.01988094,0.0009834069,0.00005571489,0.0001303127,0.0002398416],"genre_scores_gemma":[0.9876959,0.0002642876,0.000512756,0.0001639151,0.0001765016,0.0001833135,0.00003634195,0.00004507521,0.01092185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2358894,"threshold_uncertainty_score":0.9301655,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136982714","doi":"10.1016/j.ijpharm.2005.10.008","title":"Interactions of oleic acid and model stratum corneum membranes as seen by 2H NMR","year":2005,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":93,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"National Research Council Canada; Danmarks Grundforskningsfond","keywords":"Oleic acid; Membrane; Palmitic acid; Chemistry; Stratum corneum; Lamellar structure; Chromatography; Penetration (warfare); Ceramide; Phospholipid; Fatty acid; Crystallography; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.08379440374646817,"gpt":0.4655005703010683,"spread":0.3817061665546001,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000464758,0.0002350734,0.0003080411,0.0002483433,0.00008446073,0.00002270108,0.0005930949,0.0001439759,0.001068991],"category_scores_gemma":[0.00007198961,0.0002332883,0.0001497863,0.00009637039,0.0002629234,0.0006443317,0.00009991078,0.001090777,0.00002990044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001363828,"about_ca_system_score_gemma":0.0001479458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004022443,"about_ca_topic_score_gemma":0.00000526845,"domain_scores_codex":[0.9979982,0.0001609721,0.0008711884,0.0001871621,0.0005109378,0.0002715676],"domain_scores_gemma":[0.9981029,0.0002711356,0.0006288017,0.00009794736,0.0006415158,0.0002576793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00152384,0.001095252,0.001654839,0.00007101567,0.001563248,0.00009748412,0.001145076,0.07419448,0.8564214,0.0008300088,0.005684513,0.05571885],"study_design_scores_gemma":[0.00341616,0.0001051923,0.000048341,0.00005860234,0.0003552554,0.0005451256,0.0002021047,0.1203581,0.6436399,0.0007595314,0.2302714,0.0002402043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9615305,0.008144774,0.01203719,0.007555254,0.003877765,0.000308414,0.0005592437,0.00004299279,0.005943848],"genre_scores_gemma":[0.9862084,0.007658475,0.001646478,0.002878286,0.0004953798,0.000004332857,0.00001928235,0.00002788524,0.001061494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2245869,"threshold_uncertainty_score":0.9998442,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2799851200","doi":"10.2147/ccid.s162724","title":"Current trends in needle-free jet injection: an update","year":2018,"lang":"en","type":"review","venue":"Clinical Cosmetic and Investigational Dermatology","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":92,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; McGill University","funders":"","keywords":"Medicine; Injector; Drug delivery; Jet (fluid); Biomedical engineering; Surgery; Medical physics; Nanotechnology; Materials science; Mechanics; Mechanical engineering","retraction":null,"screen_n_in":null,"score":{"opus":0.3718982194215764,"gpt":0.5576412837990901,"spread":0.1857430643775137,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00117784,0.0006741568,0.002101804,0.0006568523,0.0002406945,0.00003026296,0.0008179629,0.001446153,0.00115079],"category_scores_gemma":[0.0005954896,0.0006075883,0.0003697856,0.0007031395,0.002883717,0.0002634556,0.0003467093,0.002882109,0.0003532456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009097136,"about_ca_system_score_gemma":0.0004326855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005220841,"about_ca_topic_score_gemma":0.00003374994,"domain_scores_codex":[0.9923062,0.003347978,0.002397142,0.001067075,0.0002414063,0.000640157],"domain_scores_gemma":[0.9961646,0.001814473,0.0006442888,0.0005772369,0.0001429832,0.0006564646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006872491,0.0005225225,0.003555556,0.001875479,0.0002381716,0.00007971235,0.00005494223,0.000009230508,7.028499e-8,0.008361869,0.03030188,0.9549319],"study_design_scores_gemma":[0.001460035,0.0002091051,0.0005014816,0.0007395943,0.0007651253,0.0006010066,0.00001078101,0.0007785889,0.000001033017,0.01292096,0.9814472,0.0005650652],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009126256,0.992487,0.000213012,0.0007790714,0.003654648,0.0005323627,0.0003040386,0.00008751588,0.00102979],"genre_scores_gemma":[0.0003311545,0.9932659,0.000816386,0.003051899,0.0008377388,0.0001911358,0.001298474,0.00006209351,0.0001452483],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9543668,"threshold_uncertainty_score":0.9998502,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2605641231","doi":"10.1016/j.nano.2017.04.010","title":"Enhancing targeted antibiotic therapy via pH responsive solid lipid nanoparticles from an acid cleavable lipid","year":2017,"lang":"en","type":"article","venue":"Nanomedicine Nanotechnology Biology and Medicine","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":92,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Concordia University","funders":"","keywords":"Solid lipid nanoparticle; In vivo; Staphylococcus aureus; Chemistry; Dispersity; Zeta potential; Antibiotics; In vitro; Antibacterial activity; Particle size; Vancomycin; Microbiology; Chromatography; Bacteria; Nanoparticle; Biochemistry; Nanotechnology; Biology; Materials science; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.05944571674784436,"gpt":0.429833548515051,"spread":0.3703878317672066,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["sts"],"category_scores_codex":[0.001590651,0.0006840675,0.001356905,0.0004892175,0.001734196,0.00001652976,0.001172693,0.001870763,0.001215261],"category_scores_gemma":[0.001226974,0.0005379117,0.0000867909,0.0002428725,0.006270163,0.0003721954,0.0003077131,0.001855983,0.00009630968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008299255,"about_ca_system_score_gemma":0.0001324129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003214433,"about_ca_topic_score_gemma":0.0001949291,"domain_scores_codex":[0.9956065,0.0006776476,0.001023131,0.001241322,0.0002159145,0.001235505],"domain_scores_gemma":[0.9966076,0.0006862866,0.000707082,0.001281879,0.000237845,0.000479313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001838555,0.0002704428,0.01138049,0.00002561899,0.0003434009,0.0001324859,0.0007567547,0.000003678357,0.8310617,0.0004510937,0.0003808844,0.1533549],"study_design_scores_gemma":[0.01048889,0.003708748,0.007377035,0.00018916,0.000306938,0.0001237041,0.0006748867,0.000384682,0.9082907,0.003344993,0.06452926,0.0005810369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9574637,0.01475262,0.001915887,0.0198679,0.004279873,0.0008121994,0.00007836161,0.0004174398,0.0004119847],"genre_scores_gemma":[0.9737647,0.01513787,0.0007079509,0.008204275,0.001630039,0.00005417728,0.0001473468,0.00006423389,0.000289422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1527739,"threshold_uncertainty_score":0.9997072,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2762722794","doi":"10.3390/pharmaceutics9040043","title":"Revolutionizing Therapeutic Drug Monitoring with the Use of Interstitial Fluid and Microneedles Technology","year":2017,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":92,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; University of Alberta","funders":"","keywords":"Therapeutic drug monitoring; Drug; Interstitial fluid; Intensive care medicine; Medicine; Biomedical engineering; Pharmacology; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.4745928844311885,"gpt":0.5124721242419804,"spread":0.03787923981079189,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005550194,0.0007270244,0.001397425,0.0003564145,0.000790126,0.00007568092,0.001057289,0.0005745072,0.00006298806],"category_scores_gemma":[0.00006404293,0.0005088305,0.0002388289,0.0002950406,0.002026606,0.0003009497,0.0004175942,0.002475543,0.00002618173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001840638,"about_ca_system_score_gemma":0.0002425216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000136044,"about_ca_topic_score_gemma":0.00000657258,"domain_scores_codex":[0.9970942,0.00060038,0.0007687886,0.0005918568,0.0002600622,0.000684723],"domain_scores_gemma":[0.9970362,0.0009891952,0.0009076185,0.0007200149,0.0001880784,0.0001588577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001453294,0.0001238791,0.0003362191,0.005594076,0.001611769,0.00005582119,0.0003689008,0.0001074958,0.0002466355,0.0001962981,0.0004220128,0.9907916],"study_design_scores_gemma":[0.0007535103,0.00005665231,0.00000389377,0.002902437,0.004456606,0.0001852594,0.0001193277,0.000241015,0.001142878,0.0000250952,0.9896123,0.0005009762],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003269696,0.9953649,0.0007063067,0.0003786418,0.001471037,0.001331825,0.0001965714,0.0001083572,0.0001154069],"genre_scores_gemma":[0.005566926,0.9921796,0.0008507677,0.0001814453,0.0003803626,0.0001557342,0.00002397244,0.0001170678,0.0005440735],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9902906,"threshold_uncertainty_score":0.9998258,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}