{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":195,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":195,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"2b2f6c39ce6e","filters":{"topic":"Cancer Mechanisms and Therapy"}},"results":[{"id":"W2099825600","doi":"10.3324/haematol.2009.017079","title":"PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers","year":2010,"lang":"en","type":"review","venue":"Haematologica","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":368,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; Gertrude von Meissner-Stiftung; Karolinska Institutet; VINNOVA; Novartis Foundation; Krebsliga Beider Basel; Stiftelsen för Strategisk Forskning; Knut och Alice Wallenbergs Stiftelse; National Research Foundation; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust","keywords":"PIM1; Kinase; Biology; Cancer research; AKT3; Kinome; Serine; Threonine; Cell biology; Phosphorylation","retraction":null,"screen_n_in":null,"score":{"opus":0.06871072317786502,"gpt":0.3507607535035781,"spread":0.2820500303257131,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003581909,0.0004476992,0.002642023,0.0001618966,0.00007411536,0.00002285416,0.0002008991,0.0004160281,0.000103149],"category_scores_gemma":[0.00005804022,0.0002261584,0.0002241921,0.0002964577,0.0003692231,0.00003064733,0.00006622908,0.0003782788,0.000001916279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002644515,"about_ca_system_score_gemma":0.0002018711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009310497,"about_ca_topic_score_gemma":0.0001081514,"domain_scores_codex":[0.998281,0.0001445511,0.0006047971,0.0004571426,0.0002039721,0.0003085607],"domain_scores_gemma":[0.9987445,0.0002541128,0.0003977073,0.0004772518,0.00005299504,0.00007342169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001533098,0.0001818457,0.0003708311,0.01297559,0.0001684444,0.000886921,0.0004204006,1.126686e-7,0.0003921875,0.005711666,0.0001611555,0.9785776],"study_design_scores_gemma":[0.001306259,0.001087575,0.000696387,0.008771162,0.0003828457,0.01051673,0.0003108591,0.00000325257,0.000374545,0.001194353,0.9748265,0.0005294895],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03379299,0.9644004,0.000006404425,0.0002440165,0.0001001735,0.001238528,0.00004043333,0.00003143604,0.0001455728],"genre_scores_gemma":[0.007811766,0.9909807,0.0003443258,0.0003658236,0.0000471004,0.0003669658,0.00001996022,0.00003239317,0.00003099215],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.978048,"threshold_uncertainty_score":0.922247,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2024774077","doi":"10.1074/jbc.m303083200","title":"Conditional Knock-out of Integrin-linked Kinase Demonstrates an Essential Role in Protein Kinase B/Akt Activation","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":277,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Vancouver Hospital and Health Sciences Centre; BC Cancer Agency; McGill University; University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation; Michael Smith Health Research BC; Shriners Hospitals for Children","keywords":"Protein kinase B; Integrin-linked kinase; ASK1; Cell biology; Mitogen-activated protein kinase kinase; MAP kinase kinase kinase; Kinase; Protein kinase A; Chemistry; Cancer research; Signal transduction; Cyclin-dependent kinase 2; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.02342659775697437,"gpt":0.2882729451784593,"spread":0.2648463474214849,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002851379,0.0001170787,0.0003154064,0.00004063105,0.00002109857,0.000008398146,0.00007643041,0.0001977499,0.0008240901],"category_scores_gemma":[0.0002073815,0.00008165778,0.0001192233,0.00009302532,0.00008731749,0.00007060244,0.000008836076,0.0003778635,9.532079e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007575034,"about_ca_system_score_gemma":0.0001799648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005395228,"about_ca_topic_score_gemma":0.000001421644,"domain_scores_codex":[0.9990502,0.00004859132,0.00045128,0.0001332946,0.0001788848,0.0001377347],"domain_scores_gemma":[0.9992533,0.00003785582,0.0003200153,0.00009300523,0.0001713967,0.0001243745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007420061,0.0005571764,0.001515257,0.00003468205,0.00002987552,0.00005203552,0.00003338194,0.000008208251,0.9955187,0.0003715351,0.00001076889,0.001126328],"study_design_scores_gemma":[0.001918992,0.0006058736,0.00260898,0.0001694182,0.00001327008,0.00008884219,0.00039807,0.00002107848,0.9879354,0.005793099,0.0003613164,0.00008570896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983971,0.0002093466,0.0005235428,0.0001480484,0.00004272078,0.0001166778,0.000009037195,0.000006404498,0.0005471827],"genre_scores_gemma":[0.9985369,0.00003275265,0.00106962,0.00006184104,0.00021083,0.000006612653,0.00002678695,0.000006237289,0.00004844739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007583395,"threshold_uncertainty_score":0.9023209,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2169991618","doi":"10.1126/scisignal.2000546","title":"Eukaryotic Protein Domains as Functional Units of Cellular Evolution","year":2009,"lang":"en","type":"article","venue":"Science Signaling","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University of Ottawa; Mount Sinai Hospital","funders":"","keywords":"Biology; Protein domain; Chromatin; Proteome; Architecture domain; Computational biology; Cell biology; Function (biology); Epigenetics; Domain (mathematical analysis); Genetics; DNA; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01987859976724781,"gpt":0.2557522376385124,"spread":0.2358736378712646,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005100531,0.00006899571,0.0001152688,0.0001656796,0.0001487243,0.00001346812,0.00008334466,0.00002909168,0.0002741833],"category_scores_gemma":[0.00006427026,0.00005905914,0.00003499653,0.001010679,0.0001452921,0.0001326913,0.000009801108,0.0000839511,0.00001493507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000119946,"about_ca_system_score_gemma":0.0006376154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003204826,"about_ca_topic_score_gemma":8.207749e-7,"domain_scores_codex":[0.9989024,0.00001166292,0.0001488462,0.0001980245,0.0005391465,0.0001999475],"domain_scores_gemma":[0.9994427,0.000008216069,0.00006483632,0.000146616,0.0002402004,0.00009745308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006091093,0.00003565661,0.00007271115,0.000008533595,0.000003005159,0.000005154594,0.0001003259,0.0001477462,0.9569719,0.0409887,0.000005606987,0.001599768],"study_design_scores_gemma":[0.0006107547,0.0006605454,0.002682466,0.0001380005,0.00001295135,0.0000152523,0.0001966698,0.0009104229,0.9701468,0.02442947,0.0001185824,0.00007805706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9604535,0.00020175,0.03716575,0.0003030855,0.000136551,0.0002449754,0.0000011904,0.00002933872,0.001463937],"genre_scores_gemma":[0.9978276,0.000001502146,0.001414023,0.0001824094,0.0001219825,0.000003424978,0.000001954524,0.000004151713,0.0004429016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03737423,"threshold_uncertainty_score":0.3002114,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2068605060","doi":"10.4161/cbt.8.9.8210","title":"PIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"DOD Prostate Cancer Research Program; University of Lethbridge; U.S. Department of Defense","keywords":"PIM1; PI3K/AKT/mTOR pathway; Phosphorylation; Protein kinase B; Wortmannin; Cell biology; Kinase; Protein phosphorylation; Protein kinase A; RPTOR; Biology; Autophagy-related protein 13; Cancer research; Chemistry; Signal transduction; Serine","retraction":null,"screen_n_in":null,"score":{"opus":0.01742005913855463,"gpt":0.2955231851807296,"spread":0.278103126042175,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001644537,0.0001795854,0.0003222002,0.00008558633,0.00005155542,0.00001047867,0.00005740645,0.0001869274,0.0002764838],"category_scores_gemma":[0.000004387006,0.0001441987,0.00005022594,0.0001636096,0.00007997751,0.00006248101,0.000007874251,0.0001806994,0.000003094076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000127734,"about_ca_system_score_gemma":0.0001052394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002975619,"about_ca_topic_score_gemma":0.00006725888,"domain_scores_codex":[0.9990965,0.00005878846,0.000158875,0.0003588733,0.00006557263,0.0002613549],"domain_scores_gemma":[0.9995482,0.00001929442,0.00008941878,0.0002190924,0.00004284481,0.00008115521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001222934,0.00009512127,0.001294254,0.000006508588,0.00002428655,0.000004646502,0.0002166957,0.000001641152,0.7357501,0.0003706846,0.00005886519,0.2609542],"study_design_scores_gemma":[0.003849735,0.001484217,0.06323922,0.00008571647,0.00001021288,0.000004017875,0.00002426826,0.00007823425,0.9132639,0.004023932,0.01374351,0.0001930521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863101,0.00920395,0.0001124609,0.003134622,0.0001791206,0.0008790503,0.00001206486,0.00004961877,0.000119038],"genre_scores_gemma":[0.9925193,0.004870193,0.0002910929,0.00165316,0.0002142427,0.0001169828,0.000008609125,0.00001695286,0.0003094927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2607612,"threshold_uncertainty_score":0.5880253,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2102569350","doi":"10.1161/atvbaha.110.218149","title":"Induction of MicroRNA-1 by Myocardin in Smooth Muscle Cells Inhibits Cell Proliferation","year":2010,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Libin Cardiovascular Institute of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Myocardin; Downregulation and upregulation; microRNA; Cell growth; Cell biology; Biology; Chemistry; Molecular biology; Serum response factor; Cancer research; Transcription factor; Gene; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01524642113651324,"gpt":0.2553358028760123,"spread":0.2400893817394991,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002597581,0.0001496224,0.0003861989,0.000111712,0.00004780736,0.00001336303,0.00004838048,0.0002271916,0.00008962158],"category_scores_gemma":[0.000005889372,0.0001302869,0.0001043732,0.0001486277,0.00009793611,0.00006632918,0.00002842237,0.0001987455,0.00000429853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001772947,"about_ca_system_score_gemma":0.00002913807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002225906,"about_ca_topic_score_gemma":0.0001430269,"domain_scores_codex":[0.9990519,0.00005656422,0.0002928485,0.0003175753,0.00007990721,0.0002012003],"domain_scores_gemma":[0.9995244,0.00001375295,0.00009978683,0.0002373404,0.0000523292,0.00007235378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000005661171,0.0001975127,0.01576282,0.00003010144,0.00002910839,1.524284e-8,0.0003164288,2.182962e-7,0.9812413,0.000109443,0.000134867,0.002172555],"study_design_scores_gemma":[0.001896921,0.0004864138,0.5829636,0.0000392132,0.00004301816,2.241847e-7,0.00009183268,0.00003014404,0.4094828,0.00007968628,0.004751286,0.0001347999],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985812,0.0000787419,0.0002319016,0.0003368765,0.0003013661,0.0003585708,0.00002070954,0.00001727945,0.00007331587],"genre_scores_gemma":[0.9974073,0.001508925,0.0005768098,0.0003276886,0.00008018949,0.00003619897,0.0000392644,0.000019331,0.000004290601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5717584,"threshold_uncertainty_score":0.5312947,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071217673","doi":"10.1016/j.chembiol.2011.05.010","title":"High-Throughput Kinase Profiling: A More Efficient Approach toward the Discovery of New Kinase Inhibitors","year":2011,"lang":"en","type":"article","venue":"Chemistry & Biology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Human Genome Research Institute; National Cancer Institute; National Institutes of Health; Wellcome Trust; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Life Technologies Corporation","keywords":"Kinase; PIM1; High-throughput screening; Drug discovery; Computational biology; Biology; Biochemistry; Chemistry; Enzyme; Serine","retraction":null,"screen_n_in":null,"score":{"opus":0.03665035969850917,"gpt":0.2710158048834436,"spread":0.2343654451849345,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001254421,0.0001902465,0.0003490884,0.0000186415,0.00003742737,0.000005497257,0.0001740435,0.0001825952,0.000115702],"category_scores_gemma":[0.0000461579,0.0001180556,0.0001479059,0.0001404649,0.0002652808,0.0000180758,0.00008404301,0.0002088068,0.000003199507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005246939,"about_ca_system_score_gemma":0.0002188537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000309812,"about_ca_topic_score_gemma":5.613499e-7,"domain_scores_codex":[0.9989756,0.00001661803,0.0002798476,0.0003574291,0.0001035696,0.0002668979],"domain_scores_gemma":[0.9992068,0.00002144265,0.0001427861,0.0004721664,0.00005444096,0.000102381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000488926,0.0003183262,0.0006202571,0.0002255957,0.00008816602,0.00001394632,0.002190695,0.000006171747,0.9926499,0.001312771,0.0003113704,0.001773842],"study_design_scores_gemma":[0.001220667,0.0001878,0.0002332813,0.00003869408,0.00006428292,0.0000333729,0.00104909,0.00005739226,0.9952558,0.0005427434,0.001188931,0.0001279951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946811,0.001124052,0.001815873,0.0006190946,0.0002485388,0.0003132657,0.00002883872,0.00003906361,0.001130216],"genre_scores_gemma":[0.9964809,0.00005199305,0.002062721,0.0002645591,0.0005000957,0.00003686664,0.00007394791,0.00002091661,0.0005079795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002605816,"threshold_uncertainty_score":0.4814168,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2803557794","doi":"10.1038/s41416-018-0082-1","title":"Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers","year":2018,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"National Cancer Institute; Leukemia and Lymphoma Society; AstraZeneca","keywords":"Medicine; Rash; Tolerability; Pharmacology; Dosing; Adverse effect; Pharmacokinetics; Pharmacodynamics; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03793464846920844,"gpt":0.390106849052119,"spread":0.3521722005829105,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002591618,0.00009695244,0.0005196061,0.0001114673,0.00003864708,0.00001625427,0.00004669921,0.00006517701,0.0001036772],"category_scores_gemma":[0.0001005333,0.00008472703,0.00007051813,0.0001431189,0.0002339927,0.0001618425,0.0000178867,0.0002120822,3.378663e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002108224,"about_ca_system_score_gemma":0.0003411596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001282311,"about_ca_topic_score_gemma":0.008850762,"domain_scores_codex":[0.9989818,0.00003778282,0.0004810581,0.0001246832,0.0002231935,0.0001515222],"domain_scores_gemma":[0.9991124,0.00002163112,0.0002947795,0.00005675617,0.0004242323,0.00009019398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005139815,0.000626074,0.001132251,0.0002074906,0.0003125024,0.001621122,0.002195769,0.000007818827,0.2014935,0.0001706183,0.003066371,0.7840267],"study_design_scores_gemma":[0.04956471,0.02176593,0.01136427,0.01409652,0.000483822,0.00790055,0.003968114,0.0006821937,0.8735375,0.003835178,0.01221119,0.0005900197],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9597502,0.03904639,0.0001219378,0.0003982655,0.0004236017,0.0001883039,0.0000230065,0.000004876281,0.00004337412],"genre_scores_gemma":[0.9858659,0.01267138,0.000482016,0.0003532182,0.0005460765,0.00001756181,8.160844e-7,0.00001122215,0.00005179481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7834367,"threshold_uncertainty_score":0.4938933,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1588676742","doi":"10.4049/jimmunol.168.2.744","title":"CD40 Signaling in B Cells Regulates the Expression of the Pim-1 Kinase Via the NF-κB Pathway","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute","keywords":"CD40; Signal transduction; Kinase; Biology; Cell biology; NF-κB; Cell growth; Cell culture; Phosphorylation; Molecular biology; Cancer research; Cytotoxic T cell; Biochemistry; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01364503355539663,"gpt":0.2223810766981143,"spread":0.2087360431427177,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00107327,0.0001179485,0.0002834756,0.00005849064,0.0001567571,0.000007580438,0.0005166043,0.00008328305,0.0004214743],"category_scores_gemma":[0.00004684403,0.00003987489,0.0001600849,0.0001935264,0.0002431136,0.00004177649,0.00008274188,0.0006253337,0.000005688349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004747287,"about_ca_system_score_gemma":0.00004471567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006725675,"about_ca_topic_score_gemma":0.0000131088,"domain_scores_codex":[0.9986022,0.0004420909,0.0004618875,0.00006792307,0.00022748,0.000198454],"domain_scores_gemma":[0.9985104,0.0003651029,0.0005107888,0.000490577,0.0001030649,0.00002005733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004439212,0.00008360347,0.00003397463,0.000005828723,0.00006704765,0.00001016418,0.003430664,0.0001542466,0.9880588,0.0001772891,0.000278406,0.007256056],"study_design_scores_gemma":[0.001331587,0.0004684015,0.0009215984,0.0002528939,0.00006122667,0.0003638017,0.001416154,0.0001074592,0.9890755,0.002647598,0.003302975,0.00005082697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764391,0.01346806,0.0001438244,0.008994036,0.000557807,0.0002259476,0.000001512223,0.000004112784,0.0001655811],"genre_scores_gemma":[0.997265,0.001502431,0.00004983605,0.0006382602,0.0001649625,0.000002662899,1.282567e-7,0.00001491555,0.000361777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02082591,"threshold_uncertainty_score":0.4614848,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2102954277","doi":"10.1084/jem.20110846","title":"Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma","year":2011,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center; American Society of Clinical Oncology; Leukemia Research Foundation; Lymphoma Research Foundation; Canadian Cancer Society Research Institute; Dana Foundation","keywords":"Kinase; Cancer research; PIM1; Protein kinase B; PI3K/AKT/mTOR pathway; Translation (biology); Biology; Signal transduction; EIF4E; Cell biology; Phosphorylation; Gene; Genetics; Messenger RNA","retraction":null,"screen_n_in":null,"score":{"opus":0.03904586285399698,"gpt":0.2933396574992813,"spread":0.2542937946452843,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008702692,0.0001394007,0.0003759612,0.0001062075,0.00005561674,0.000004226201,0.00008338374,0.00004311383,0.0007136532],"category_scores_gemma":[0.00002157748,0.00008409149,0.00003892711,0.00008983847,0.0001114181,0.00009011397,0.00001394487,0.0001356171,6.954955e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008056062,"about_ca_system_score_gemma":0.00003721384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000565609,"about_ca_topic_score_gemma":0.000009232251,"domain_scores_codex":[0.9987877,0.00009183299,0.0004751827,0.00009711363,0.000376758,0.0001714178],"domain_scores_gemma":[0.999413,0.00009774909,0.0002301033,0.00008849319,0.00004889936,0.0001218021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001658341,0.0002557803,0.0006889338,0.00001241862,0.00006694866,0.00008327684,0.01419954,0.000002642366,0.9788377,0.00004751042,0.0002784203,0.003868519],"study_design_scores_gemma":[0.01275093,0.004009284,0.0008002549,0.0006140436,0.0001358316,0.0006189519,0.02804836,0.000208629,0.9519807,0.0002582507,0.0004200386,0.0001547453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9590265,0.03852744,0.0005413063,0.0007036662,0.000387318,0.0001959831,0.000001734098,0.000007367887,0.0006087006],"genre_scores_gemma":[0.9981001,0.000920722,0.0002039521,0.0004156665,0.0002828351,0.00000271511,0.000002178033,0.00001754094,0.00005431437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03907359,"threshold_uncertainty_score":0.7814001,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2064582293","doi":"10.1158/0008-5472.can-14-2387","title":"SND1 Acts Downstream of TGFβ1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"RHOA; Cancer research; SMAD; Ubiquitin ligase; Metastasis; Downregulation and upregulation; Chemistry; Transforming growth factor; Breast cancer; Epithelial–mesenchymal transition; Cancer; Signal transduction; Cell biology; Ubiquitin; Biology; Internal medicine; Medicine; Biochemistry; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.1355516820982018,"gpt":0.4510824402073585,"spread":0.3155307581091567,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008170945,0.0001464429,0.0004753203,0.0002932844,0.0000475883,0.00001438118,0.0001607504,0.0000773718,0.0006705826],"category_scores_gemma":[0.00006020949,0.000114491,0.00006606951,0.0007021046,0.0001858729,0.00007278057,0.0001212216,0.0002412191,0.000006814529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002582933,"about_ca_system_score_gemma":0.001038409,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007910122,"about_ca_topic_score_gemma":0.0007699151,"domain_scores_codex":[0.9980385,0.00007304352,0.00026778,0.0003419344,0.0008478186,0.0004308783],"domain_scores_gemma":[0.9979472,0.000038936,0.00007582357,0.0004281807,0.0009794856,0.0005303416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004864732,0.0005013079,0.01223775,0.0007966702,0.0005999671,0.00003649647,0.004676056,0.00003913596,0.4195427,0.001393448,0.007680859,0.5476308],"study_design_scores_gemma":[0.004726507,0.001938461,0.009492568,0.001103263,0.0001336822,0.00005449806,0.001239908,0.00003233925,0.9416826,0.0009307829,0.03841564,0.0002497586],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899709,0.003163288,0.00002745522,0.004188345,0.0001313937,0.0008008945,0.0003878176,0.00001691255,0.00131298],"genre_scores_gemma":[0.996658,0.001343427,0.0004219083,0.000114425,0.0002142387,0.0001956958,0.000005320624,0.00003481102,0.001012223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5473811,"threshold_uncertainty_score":0.9986963,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2132011506","doi":"10.1021/jm901018f","title":"Synthesis, Kinase Inhibitory Potencies, and in Vitro Antiproliferative Evaluation of New Pim Kinase Inhibitors","year":2009,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Medical Research Council; Canadian Institutes of Health Research; Wellcome Trust","keywords":"Chemistry; Carbazole; DU145; Kinase; In vitro; Lead compound; Structure–activity relationship; Biochemistry; Stereochemistry; Cancer cell; Cancer; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.02125981076005875,"gpt":0.2935554209193602,"spread":0.2722956101593015,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001336647,0.0001586745,0.0005226856,0.000128147,0.00002509358,0.000007422446,0.00006856487,0.0001254802,0.0001124888],"category_scores_gemma":[0.0005453251,0.0001255458,0.000098095,0.0001801768,0.00007305094,0.0001003216,0.00001012188,0.0004025646,2.650633e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002294116,"about_ca_system_score_gemma":0.0009557296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002675893,"about_ca_topic_score_gemma":0.000001830959,"domain_scores_codex":[0.998021,0.00004738326,0.0006241981,0.0001504517,0.0009904207,0.0001665455],"domain_scores_gemma":[0.9986966,0.00006195799,0.0004445349,0.000135272,0.0003989275,0.0002627401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001871594,0.0001770766,0.0002436624,0.00009095428,0.00003666754,0.0001485276,0.0005106432,0.000007279833,0.9186902,0.000002986257,0.0006135317,0.07760688],"study_design_scores_gemma":[0.004500764,0.0004595906,0.003425965,0.001236128,0.0002559631,0.0005505488,0.001095249,0.0001430266,0.9873703,0.0005676381,0.0002931599,0.0001016502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870831,0.009630569,0.00005129004,0.002569783,0.0001334888,0.0001446101,0.000002888547,0.000004577288,0.000379647],"genre_scores_gemma":[0.9976816,0.0004485848,0.0004774251,0.0002960875,0.001032777,0.000001796463,0.000002274238,0.00000994879,0.0000495145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07750523,"threshold_uncertainty_score":0.5119609,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2027521216","doi":"10.1074/jbc.m114.625046","title":"Tudor Staphylococcal Nuclease (Tudor-SN), a Novel Regulator Facilitating G1/S Phase Transition, Acting as a Co-activator of E2F-1 in Cell Cycle Regulation","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"Natural Science Foundation of Tianjin City; National Natural Science Foundation of China; National Science Fund for Distinguished Young Scholars; National Science Foundation","keywords":"Biology; E2F; Cell cycle; Cell biology; Ectopic expression; Cyclin A; Molecular biology; Cyclin-dependent kinase 1; Cyclin-dependent kinase; Cell; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.04267893337544697,"gpt":0.3200137878931439,"spread":0.2773348545176969,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005807097,0.0001640664,0.0004986862,0.00005368345,0.00003270037,0.00001149721,0.00009250086,0.000205052,0.0003315965],"category_scores_gemma":[0.0003177995,0.0001240565,0.0001959086,0.0001732507,0.00008157347,0.0000986345,0.00001358433,0.000369287,0.000001780358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001856954,"about_ca_system_score_gemma":0.0002201835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001931717,"about_ca_topic_score_gemma":4.693193e-7,"domain_scores_codex":[0.998538,0.00003887535,0.0007090345,0.0001932365,0.0003153224,0.0002054913],"domain_scores_gemma":[0.9986898,0.000103551,0.0005192562,0.000139757,0.0002585215,0.0002891326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00345679,0.0009381002,0.0002431086,0.0001068693,0.00003826261,0.00003810719,0.0008509253,0.00007852521,0.9916085,0.000009304198,0.00005954117,0.002571953],"study_design_scores_gemma":[0.01136139,0.001487074,0.0008976728,0.0002626162,0.00003475591,0.0001675225,0.003881576,0.0006411051,0.9799474,0.0005391412,0.0006177086,0.0001620287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973297,0.0001752283,0.001429159,0.0002888589,0.00004685051,0.0001472954,0.00003865985,0.00001350662,0.0005307164],"genre_scores_gemma":[0.9972053,0.00001401168,0.002332499,0.0001193272,0.0002597916,0.000003906433,0.00001564266,0.00001286696,0.00003671629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01166111,"threshold_uncertainty_score":0.5058876,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2147186597","doi":"10.1158/1535-7163.mct-12-1166","title":"PRIMA-1Met/APR-246 Displays High Antitumor Activity in Multiple Myeloma By Induction of p73 and Noxa","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Moffitt Cancer Center","keywords":"Multiple myeloma; Apoptosis; Dexamethasone; Cancer research; Gene knockdown; In vivo; Gene silencing; Cell culture; Doxorubicin; Chemistry; Medicine; Biology; Immunology; Internal medicine; Chemotherapy","retraction":null,"screen_n_in":null,"score":{"opus":0.01821987219354484,"gpt":0.2682079650606845,"spread":0.2499880928671396,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009473535,0.0001960318,0.0003694488,0.0001011377,0.00003989039,0.00002010795,0.00007385432,0.0001228888,0.0001096573],"category_scores_gemma":[0.000005844032,0.0001773115,0.00006475877,0.0002341398,0.00009236372,0.0001099388,0.00003116123,0.0002169961,0.000003114901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001300243,"about_ca_system_score_gemma":0.00008663585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002631068,"about_ca_topic_score_gemma":0.0001226578,"domain_scores_codex":[0.9989215,0.00004755087,0.0002218351,0.0003030241,0.000247892,0.0002581955],"domain_scores_gemma":[0.9993819,0.00002079476,0.0001243857,0.0002911141,0.0000977747,0.00008403139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002014384,0.0001756548,0.004602395,0.00007809603,0.000117315,0.000008052591,0.0001898354,0.000009763952,0.9161077,0.0001861072,0.00005957069,0.07826403],"study_design_scores_gemma":[0.003136856,0.000350049,0.06784117,0.0001156158,0.00009430216,0.00001102806,0.00006212184,0.0009083123,0.9236659,0.0005779108,0.003011836,0.0002249135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912427,0.003190099,0.003285001,0.001296703,0.0002114083,0.0006478342,0.00003248397,0.00002503415,0.00006873988],"genre_scores_gemma":[0.9967654,0.001193191,0.0006406422,0.001052178,0.00005470031,0.0001091829,0.00001248633,0.00004378796,0.0001284763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07803912,"threshold_uncertainty_score":0.7230552,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2162877239","doi":"10.1371/journal.pone.0007112","title":"Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"PIM1; Kinase; Kinome; Protein kinase domain; Computational biology; Biology; Serine; Bioinformatics; Chemistry; Cell biology; Biochemistry; Phosphorylation; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.02566523226393111,"gpt":0.2322677900500427,"spread":0.2066025577861116,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002689046,0.00008319274,0.0002075346,0.00003900927,0.00002329006,0.00000530057,0.00006885105,0.00004089043,0.0003275962],"category_scores_gemma":[0.000006557984,0.00004979526,0.00002088547,0.0001791348,0.00003196243,0.00003477275,0.000009153589,0.0001285087,6.936302e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003249481,"about_ca_system_score_gemma":0.00005551572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004663691,"about_ca_topic_score_gemma":0.0001946743,"domain_scores_codex":[0.9993773,0.00001784811,0.0001170941,0.0001219279,0.0002467237,0.0001191751],"domain_scores_gemma":[0.9995732,0.000005265393,0.00004952888,0.000265114,0.00005513312,0.00005178769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004727106,0.0007838571,0.001772596,0.00002979595,0.0000296287,0.000005989605,0.0004975069,0.000001464917,0.9956014,0.0004645988,0.00001752134,0.0003229285],"study_design_scores_gemma":[0.00279937,0.001542822,0.06401063,0.000249838,0.00007313752,0.000009317049,0.0001903976,0.00008407063,0.9293448,0.00153505,0.000060273,0.0001002655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984396,0.00004698943,0.00001232727,0.001002337,0.00001400905,0.0002928536,0.00002273094,0.00001688544,0.000152267],"genre_scores_gemma":[0.9977829,0.000004876852,0.001361049,0.00061886,0.0001401248,0.000001455282,0.00001143563,0.0000124146,0.00006687518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06625657,"threshold_uncertainty_score":0.3586949,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2165582512","doi":"10.1158/1078-0432.ccr-11-2102","title":"Significance of Dysregulated Metadherin and MicroRNA-375 in Head and Neck Cancer","year":2011,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Ontario Institute for Cancer Research; Cancer Research Institute","keywords":"Gene knockdown; Clonogenic assay; Cancer research; microRNA; Metastasis; Biology; Viability assay; In vivo; Cancer; Downregulation and upregulation; Blot; Cell growth; Medicine; Oncology; Cell; Cell culture; Internal medicine; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.3548461461497907,"gpt":0.5237625743841676,"spread":0.168916428234377,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001647668,0.0001368093,0.0005999217,0.0001592995,0.00004606781,0.00001184477,0.0001239396,0.0001736304,0.000918181],"category_scores_gemma":[0.0001180206,0.0001133469,0.00006983479,0.0004624045,0.0006216033,0.00006333287,0.0001049277,0.0006471334,0.000003380279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008810563,"about_ca_system_score_gemma":0.0004278009,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01284671,"about_ca_topic_score_gemma":0.004058785,"domain_scores_codex":[0.9979453,0.0002077892,0.000576378,0.0005000469,0.0003508224,0.0004196826],"domain_scores_gemma":[0.998832,0.0002242442,0.00008985505,0.0003231101,0.0002548817,0.0002759376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01136583,0.0009669483,0.606294,0.0007488859,0.0003878402,0.0001454012,0.002042884,0.000001587423,0.09907748,0.00218535,0.001919551,0.2748642],"study_design_scores_gemma":[0.00729182,0.002024617,0.9368328,0.0007142543,0.00005283369,0.000008428717,0.0002249281,0.0001406612,0.03620004,0.002079066,0.01420609,0.0002244103],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983848,0.01346533,0.000008692284,0.001099241,0.0001581265,0.0006441299,0.00002384132,0.00001425477,0.0007383304],"genre_scores_gemma":[0.9828479,0.01501167,0.0005085143,0.0002809232,0.0001545172,0.0001692263,0.00000156472,0.00003025444,0.0009954185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3305388,"threshold_uncertainty_score":0.9999951,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1968969270","doi":"10.1182/blood-2006-04-020305","title":"Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Cancer Institute","keywords":"Anaplastic lymphoma kinase; Autocrine signalling; Anaplastic large-cell lymphoma; Cancer research; Cell culture; Interleukin 15; Biology; Signal transduction; Lymphoma; Chemistry; Cytokine; Interleukin; Cell biology; Immunology; Internal medicine; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.00628441177861495,"gpt":0.2197124589867445,"spread":0.2134280472081296,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001416102,0.0001622288,0.0004222695,0.0001078966,0.00002150059,0.000005770598,0.0001024633,0.00006715327,0.0002789501],"category_scores_gemma":[0.00001418014,0.0001413475,0.000135628,0.0001473243,0.00003690284,0.00003007627,0.00004302694,0.00006899267,0.00001380135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002811761,"about_ca_system_score_gemma":0.0001251143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000453289,"about_ca_topic_score_gemma":0.0001956904,"domain_scores_codex":[0.9987618,0.00002929436,0.0004029199,0.0002331997,0.0003223865,0.0002503942],"domain_scores_gemma":[0.9992448,0.00004751077,0.0001819497,0.0003273518,0.0001157223,0.00008263268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007875795,0.01230187,0.002615307,0.0006882391,0.0001962597,0.0002165022,0.0002253432,0.00001222753,0.978538,0.002132117,0.0003655273,0.001921072],"study_design_scores_gemma":[0.01688072,0.001579325,0.003292107,0.0001502223,0.0002435827,0.00003206957,0.00008042667,0.0001400125,0.97543,0.0004367536,0.001594359,0.0001404484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951264,0.0005595013,0.0007055335,0.00005317705,0.0002427738,0.000337943,0.00008127481,0.00003914874,0.002854226],"genre_scores_gemma":[0.9975162,0.0000424581,0.0005463866,0.00003291617,0.0001596077,0.00001142619,0.00002424826,0.00003319692,0.001633567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01609314,"threshold_uncertainty_score":0.5763984,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2030849371","doi":"10.1074/jbc.m110.173526","title":"Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Novo Nordisk Fonden; Vetenskapsrådet; Sultan Qaboos University; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Cancerfonden; Stiftelsen för Strategisk Forskning; Novo Nordisk; Skånes universitetssjukhus; Ontario Genomics Institute; Ontario Genomics; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust","keywords":"SOCS6; SOCS3; Ubiquitin ligase; Suppressor of cytokine signaling 1; SOCS5; Ubiquitin; Suppressor of cytokine signalling; Suppressor; Chemistry; Cytokine; SOCS2; Cell biology; Biology; Biochemistry; Immunology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.02253926079041732,"gpt":0.2794855608885924,"spread":0.2569463000981751,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003286506,0.0001028924,0.0002919176,0.000011959,0.00004802328,0.00001043933,0.00009742116,0.0001435181,0.0007065515],"category_scores_gemma":[0.0002457099,0.00005303257,0.0002292692,0.00005147156,0.00009587274,0.00002741774,0.00001811532,0.0003732669,2.310371e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002193352,"about_ca_system_score_gemma":0.00004530233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003305821,"about_ca_topic_score_gemma":3.663248e-7,"domain_scores_codex":[0.9992092,0.00001183104,0.0003862571,0.0000996729,0.0001524967,0.0001405291],"domain_scores_gemma":[0.9990765,0.0001613469,0.000358385,0.0001073164,0.0002034877,0.00009294398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006716066,0.00004908671,0.00012606,0.00004903722,0.00004316973,0.000008452144,0.0000304281,0.000001050783,0.9973263,0.00004436735,0.0005652264,0.001085212],"study_design_scores_gemma":[0.001248948,0.0004413813,0.0001493879,0.00006889406,0.00004699504,0.0003084829,0.0001137679,0.00002191275,0.9945647,0.00134305,0.001629457,0.00006303385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977285,0.0002433498,0.0001873168,0.001426341,0.0001111426,0.000107374,0.00009815094,0.000006239323,0.00009156687],"genre_scores_gemma":[0.9977111,0.00003590478,0.001146803,0.0002883882,0.0007347251,0.000004966389,0.00001860013,0.000007528858,0.00005193552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002761613,"threshold_uncertainty_score":0.7736244,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2034293536","doi":"10.1038/nsmb.2186","title":"Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi","year":2011,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"RNA interference; RNA polymerase; RNA; RNA-dependent RNA polymerase; Cell biology; Polymerase; Chemistry; RNA polymerase I; Biology; Molecular biology; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.0088520354682224,"gpt":0.3119483916578735,"spread":0.3030963561896511,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001469045,0.0003976299,0.0005085488,0.0002498224,0.0001084771,0.00002101644,0.0003566511,0.000544948,0.001035077],"category_scores_gemma":[0.0000390077,0.0003056675,0.0002047567,0.000286994,0.00006543665,0.00005146831,0.0001196267,0.0006903887,0.00004006386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001115021,"about_ca_system_score_gemma":0.00008619699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005703029,"about_ca_topic_score_gemma":0.0001226522,"domain_scores_codex":[0.9978763,0.0001377768,0.0003175618,0.0007554695,0.0002549343,0.0006579015],"domain_scores_gemma":[0.9985124,0.000008404771,0.000097417,0.0006605533,0.0001260957,0.0005950526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001096151,0.00002909341,0.00009898822,0.000009218356,0.0001916307,0.0003249153,0.000566677,0.000002633979,0.9672878,0.01267238,0.0001143573,0.01760612],"study_design_scores_gemma":[0.00240837,0.002608154,0.004304827,0.00003293621,0.0001036981,0.0003350221,0.0002397741,0.000007213813,0.9739934,0.01171891,0.003719934,0.0005278033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897346,0.001289475,0.00357337,0.002123377,0.001457647,0.0008541184,0.00009499408,0.000108173,0.0007642533],"genre_scores_gemma":[0.9706892,0.00001246196,0.0119041,0.01673313,0.0003219016,0.00003902863,0.00008166494,0.00006623545,0.0001522927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01904541,"threshold_uncertainty_score":0.9999396,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2883745175","doi":"10.1016/j.dnarep.2018.07.005","title":"DNA damage response and repair in colorectal cancer: Defects, regulation and therapeutic implications","year":2018,"lang":"en","type":"review","venue":"DNA repair","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Acadia University","funders":"","keywords":"DNA damage; Biology; DNA repair; Colorectal cancer; Cancer research; Signal transduction; Cancer; Cell cycle checkpoint; Apoptosis; Kinase; Genome instability; Cell cycle; DNA mismatch repair; Bioinformatics; Cell biology; DNA; Computational biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03612270118145772,"gpt":0.3440194544074142,"spread":0.3078967532259565,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007263882,0.000344028,0.001053506,0.0002954692,0.0001084222,0.00001769379,0.00006823576,0.0003343865,0.00007898727],"category_scores_gemma":[0.00006538412,0.0002854681,0.0003047246,0.0004158752,0.0001406372,0.00004791341,0.00005600803,0.0002598251,0.00000676069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003315864,"about_ca_system_score_gemma":0.0004604814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001076656,"about_ca_topic_score_gemma":0.0003085184,"domain_scores_codex":[0.9981501,0.0002867163,0.0004908678,0.0006546333,0.0001502782,0.0002674156],"domain_scores_gemma":[0.9988087,0.0002482664,0.0002317676,0.0005007552,0.00007203732,0.0001384881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002459303,0.0002589239,0.001354711,0.01347228,0.0009366444,0.00007210452,0.0009832628,2.040513e-7,0.002672215,0.002819179,0.004117309,0.9708539],"study_design_scores_gemma":[0.0008539867,0.000545795,0.02479973,0.004689637,0.0006458414,0.0001509973,0.00002047208,0.00006273288,0.00005869834,0.0003752561,0.9674877,0.0003091833],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06866451,0.9288444,0.00000603758,0.0002488674,0.0001320877,0.001603144,0.0001008341,0.0002770204,0.0001231079],"genre_scores_gemma":[0.002247283,0.9958625,0.000264344,0.0002444129,0.0002124591,0.0005249095,0.00006806265,0.00007841783,0.0004976235],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9705447,"threshold_uncertainty_score":0.9999598,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2270601398","doi":"10.1093/infdis/jiv760","title":"Inhibition of MicroRNA 195 Prevents Apoptosis and Multiple-Organ Injury in Mouse Models of Sepsis","year":2015,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Lawson Health Research Institute; Western University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; National Natural Science Foundation of China","keywords":"microRNA; Apoptosis; Sepsis; Biology; Cell biology; Cancer research; Medicine; Immunology; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01731942892675933,"gpt":0.2683091600435717,"spread":0.2509897311168124,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002653289,0.00008660334,0.000300901,0.0001700656,0.00001791647,0.000004243656,0.00004181938,0.0000360826,0.00001285429],"category_scores_gemma":[0.000101222,0.00005861985,0.00008609895,0.0001407457,0.00005742875,0.000126734,0.00002341681,0.0001028797,2.712487e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006955225,"about_ca_system_score_gemma":0.0001207875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002167908,"about_ca_topic_score_gemma":0.0000174993,"domain_scores_codex":[0.9991962,0.00007958654,0.0003729578,0.00005447094,0.0002098127,0.00008701347],"domain_scores_gemma":[0.9991381,0.00006524284,0.0003650843,0.00011495,0.0001971555,0.0001194725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006437158,0.002280846,0.1267717,0.0003568102,0.0004599546,0.000008423065,0.005017963,0.001829507,0.8483689,0.0001049435,0.0008276499,0.007536149],"study_design_scores_gemma":[0.01253246,0.003600863,0.01108965,0.0009124106,0.0006259251,0.0001247587,0.001221767,0.0006045602,0.9570125,0.01205557,0.00003789496,0.0001816744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982326,0.0010258,0.0003083357,0.0001110001,0.00006652482,0.0001697853,0.00003556018,0.000005702046,0.00004466341],"genre_scores_gemma":[0.998767,0.0009681016,0.00005323978,0.0001203812,0.00005890151,0.000001437857,0.000001570824,0.00001302767,0.00001639764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1156821,"threshold_uncertainty_score":0.2390448,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2084903155","doi":"10.1016/j.yexcr.2004.07.029","title":"PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor","year":2004,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Ministry of Education, Culture, Sports, Science and Technology; Canada Foundation for Innovation; Wellcome Trust","keywords":"RNA splicing; Biology; Splicing factor; Retinitis pigmentosa; Phosphorylation; Minigene; SR protein; Missense mutation; Alternative splicing; Prp24; Mutant; Genetics; Gene; Mutation; Molecular biology; Cell biology; Exon; RNA","retraction":null,"screen_n_in":null,"score":{"opus":0.1533281483198266,"gpt":0.4324572184987647,"spread":0.2791290701789381,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005947481,0.0001504101,0.0002211721,0.00009181861,0.0004157345,0.00004783638,0.0002558287,0.0000643238,0.001029676],"category_scores_gemma":[0.00001284649,0.00008300671,0.0001299768,0.0003463714,0.0002455491,0.00005562769,0.0001455842,0.000395964,0.00004034246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003693326,"about_ca_system_score_gemma":0.0002113464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00221541,"about_ca_topic_score_gemma":0.00003778219,"domain_scores_codex":[0.997942,0.00008328507,0.0002746237,0.000276374,0.0009183662,0.0005053318],"domain_scores_gemma":[0.9990849,0.0001282259,0.00006994308,0.0004909887,0.0001081164,0.0001178599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003733487,0.0002132913,0.00002827428,0.00002723017,0.00004201677,0.00003400035,0.01897559,0.000001301338,0.9778025,0.0006046931,0.0001487472,0.001749017],"study_design_scores_gemma":[0.002557473,0.001033626,0.0003274379,0.00009371373,0.00000870719,0.00003005657,0.0152206,0.00004220083,0.9783384,0.0007773072,0.001482062,0.00008841253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896264,0.00316892,0.0001918248,0.00177307,0.0001080103,0.001084515,0.00001433511,0.00001572342,0.00401717],"genre_scores_gemma":[0.9976347,0.0003715978,0.0002428685,0.0003768863,0.00008157767,0.0001098902,0.000007670526,0.00003713201,0.00113764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008008305,"threshold_uncertainty_score":0.9998835,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2077860356","doi":"10.1021/jm201286z","title":"7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes","year":2011,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Kinase; Chemistry; Cocrystal; Biochemistry; Drug discovery; Structure–activity relationship; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.02554173362078691,"gpt":0.2641507190579482,"spread":0.2386089854371613,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004310245,0.0001442106,0.0003416983,0.00005817172,0.00007810141,0.00000539601,0.00008529015,0.00006824679,0.00003155753],"category_scores_gemma":[0.00006953677,0.00008007508,0.00007515056,0.000114366,0.0001079923,0.00004855598,0.00001807097,0.0001964247,1.618623e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000957949,"about_ca_system_score_gemma":0.0005464668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001972598,"about_ca_topic_score_gemma":0.00000520546,"domain_scores_codex":[0.9988882,0.000007208761,0.0003993468,0.0001193485,0.0004213585,0.0001645156],"domain_scores_gemma":[0.9989569,0.00008274629,0.0003872908,0.00009232661,0.0003225657,0.0001581703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01144905,0.00039663,0.002533364,0.0007272043,0.001311902,0.0001281009,0.01346553,0.000009447656,0.9267368,0.00007409778,0.0003331368,0.04283476],"study_design_scores_gemma":[0.003807778,0.001148924,0.001079589,0.000854341,0.0003443681,0.0005795115,0.007605413,0.00007655329,0.9839302,0.0001446937,0.0003315758,0.00009708297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961969,0.00154888,0.001097635,0.0002823441,0.00008930043,0.0001831772,0.000003078195,0.000005466341,0.000593182],"genre_scores_gemma":[0.9955168,0.00009597484,0.00378237,0.00007271339,0.0004099068,0.00001003635,0.000001443052,0.00001753517,0.00009318814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0571934,"threshold_uncertainty_score":0.3265367,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1970649373","doi":"10.4161/cc.2.3.383","title":"Pim-1 Phosphorylates the DNA Binding Domain of c-Myb","year":2003,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"MYB; Biology; Transcription factor; Phosphorylation; bZIP domain; DNA-binding protein; Cell biology; Threonine; DNA-binding domain; Serine; Molecular biology; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.007479520167238513,"gpt":0.2265291706502975,"spread":0.2190496504830589,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001860531,0.00007174471,0.0001358186,0.00002813084,0.00005772464,0.000006365166,0.00005653231,0.00003732295,0.000852398],"category_scores_gemma":[0.00000847874,0.00004717263,0.00007021674,0.0001334702,0.00003796693,0.00001801248,0.000008940325,0.00007851547,0.00004780076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002451546,"about_ca_system_score_gemma":0.00003842908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002724281,"about_ca_topic_score_gemma":0.000004243544,"domain_scores_codex":[0.9994892,0.00001979094,0.0001195435,0.0001083511,0.000117105,0.000145944],"domain_scores_gemma":[0.9996219,0.00003306159,0.00005053386,0.000226136,0.00002129595,0.00004711485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008048578,0.0001453865,0.0008668269,0.00005077749,0.00003925302,0.00001262563,0.001385076,0.000006630641,0.9811248,0.01216513,0.00135849,0.002764498],"study_design_scores_gemma":[0.001033854,0.0001335653,0.0003562516,0.00002729631,0.00002313086,0.000008764307,0.000689808,0.00001401021,0.9423112,0.00548977,0.04984509,0.00006728584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659932,0.001063891,0.0001555538,0.0002003145,0.0001984153,0.00016393,0.000002664052,0.00001844236,0.03220361],"genre_scores_gemma":[0.9968885,0.0001157873,0.000545403,0.0002513877,0.00004376805,0.000007327332,0.000001857364,0.00001615625,0.002129777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0484866,"threshold_uncertainty_score":0.9333161,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1965156600","doi":"10.1016/j.drup.2011.04.002","title":"The oncogenic PIM kinase family regulates drug resistance through multiple mechanisms","year":2011,"lang":"en","type":"review","venue":"Drug Resistance Updates","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Government of Ontario","keywords":"Efflux; Kinase; Biology; Cancer research; Pharmacology; Signal transduction; Cancer; Drug resistance; Cell biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03263143506265965,"gpt":0.2976015274292069,"spread":0.2649700923665473,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001081541,0.001446254,0.003257677,0.0001941027,0.0009595597,0.0002252828,0.001347783,0.0004912399,0.0002342911],"category_scores_gemma":[0.000180023,0.0009654578,0.001561382,0.0009306544,0.0004176005,0.0002537718,0.0002383395,0.001146671,0.0003432698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006180725,"about_ca_system_score_gemma":0.0008606339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001303225,"about_ca_topic_score_gemma":0.00242822,"domain_scores_codex":[0.9939932,0.0004070251,0.001708511,0.001662042,0.000892024,0.00133723],"domain_scores_gemma":[0.994274,0.0008357445,0.001256767,0.002931127,0.0003556075,0.0003467329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002355411,0.0006036052,0.000001442651,0.02689348,0.002785033,0.000562868,0.001971121,3.044738e-7,0.0004099339,0.2163695,0.2893827,0.4586647],"study_design_scores_gemma":[0.001138826,0.00003546255,0.000002136574,0.01514497,0.001250943,0.00001937278,0.0002778054,0.00000137805,0.001294644,0.02913539,0.9507085,0.000990559],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002428911,0.9892417,0.000312675,0.0008951024,0.001575059,0.002690139,0.0003048506,0.0003738657,0.004582366],"genre_scores_gemma":[0.00006125392,0.8896371,0.005460809,0.000544092,0.0005674492,0.0007701174,0.0003997663,0.0003661224,0.1021934],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6613258,"threshold_uncertainty_score":0.9998287,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1965568377","doi":"10.1038/bjc.2012.272","title":"PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma","year":2012,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Ministero dello Sviluppo Economico; Gertrude von Meissner-Stiftung; Ontario Ministry of Economic Development and Innovation; Canadian Institutes of Health Research; Genome Canada; Wellcome Trust; GlaxoSmithKline; Pfizer; Eli Lilly and Company","keywords":"PIM1; Cancer research; Diffuse large B-cell lymphoma; Biology; Kinase; Lymphoma; Tissue microarray; Signal transduction; Cell growth; Cell biology; Phosphorylation; Immunohistochemistry; Immunology; Serine","retraction":null,"screen_n_in":null,"score":{"opus":0.01018648345234164,"gpt":0.2936566803929901,"spread":0.2834701969406485,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003186006,0.0001069733,0.0002980519,0.00009762053,0.00005938175,0.00003104786,0.00005172868,0.00005920221,0.0002406419],"category_scores_gemma":[0.00001367839,0.00009992809,0.0000795931,0.0001104357,0.00002630218,0.0001929058,0.00001891309,0.000155223,7.018184e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000124745,"about_ca_system_score_gemma":0.00008235592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000110145,"about_ca_topic_score_gemma":0.0002621542,"domain_scores_codex":[0.9989849,0.00004333579,0.0002803139,0.0001003052,0.0002695643,0.0003215831],"domain_scores_gemma":[0.999399,0.00001919983,0.0002473713,0.0000653844,0.00008383758,0.0001852194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001035416,0.002721823,0.1105253,0.0001793974,0.0001090139,0.0006978101,0.0006569692,6.732776e-7,0.005235015,0.00003499475,0.001002536,0.8778011],"study_design_scores_gemma":[0.05050878,0.0006089456,0.7916821,0.005549015,0.0002245426,0.003159862,0.001744217,0.00008557871,0.01173876,0.0003620021,0.1339043,0.0004318447],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7606149,0.2383373,0.00006287602,0.0003033297,0.0003945383,0.0001260717,0.000009016408,0.000006711666,0.0001453211],"genre_scores_gemma":[0.9743127,0.02414207,0.0001970392,0.0007042408,0.0004672562,0.00001205316,0.000001222637,0.00002678432,0.000136691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8773692,"threshold_uncertainty_score":0.4074949,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2108375396","doi":"10.1161/atvbaha.111.230573","title":"RAGE-Dependent Activation of the Oncoprotein Pim1 Plays a Critical Role in Systemic Vascular Remodeling Processes","year":2011,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"NFAT; STAT3; Cancer research; Signal transduction; STAT protein; Small interfering RNA; Cell biology; Biology; Transcription factor; Chemistry; Transfection; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.04702396245170209,"gpt":0.2822463371705425,"spread":0.2352223747188404,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003817693,0.0001735,0.0004763314,0.00008475837,0.00008810696,0.00001117666,0.0001203368,0.0001791177,0.00007102026],"category_scores_gemma":[0.00008244409,0.0001198856,0.000149751,0.0001987302,0.0001244948,0.00008042668,0.00007150496,0.0001574674,0.000002229766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005062973,"about_ca_system_score_gemma":0.00008315382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006334626,"about_ca_topic_score_gemma":0.0001082552,"domain_scores_codex":[0.998732,0.0001303369,0.0003763703,0.0003613297,0.000151819,0.0002481081],"domain_scores_gemma":[0.9992994,0.00004086075,0.00009984003,0.0003822532,0.0001146513,0.00006297892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002428527,0.0002582852,0.02804706,0.0003118549,0.0001511451,6.552712e-8,0.002110467,0.000004885549,0.9667218,0.001508466,0.000002150776,0.000859559],"study_design_scores_gemma":[0.003452379,0.000996276,0.8750916,0.002077984,0.0002669389,0.000005744245,0.001715142,0.0007404772,0.1130077,0.002121659,0.0001594315,0.0003646778],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957643,0.0003911254,0.002900493,0.0001822107,0.00009416748,0.0005443686,0.000006173183,0.00002296626,0.00009424634],"genre_scores_gemma":[0.997218,0.001781474,0.0005911627,0.0002384243,0.00004893138,0.0000933932,0.000004254424,0.00002316331,0.000001237544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8537141,"threshold_uncertainty_score":0.4888792,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2896479296","doi":"10.1016/j.celrep.2018.09.056","title":"Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children; Ontario Institute for Cancer Research","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Ontario Institute for Cancer Research; Terry Fox Foundation; Government of Ontario; Susan G. Komen; Breast Cancer Research Foundation","keywords":"CDH1; Immune system; Breast cancer; Invasive lobular carcinoma; Cancer research; Lobular carcinoma; Breast carcinoma; Biology; Mutation; Medicine; Immunology; Genetics; Cadherin; Gene; Cancer; Invasive ductal carcinoma; Ductal carcinoma","retraction":null,"screen_n_in":null,"score":{"opus":0.009346074774385864,"gpt":0.2314113941860571,"spread":0.2220653194116712,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001354894,0.00009148818,0.0001804663,0.00004571631,0.00008893105,0.000009723542,0.00003861129,0.00005865114,0.0002458854],"category_scores_gemma":[0.00003653861,0.0000642003,0.00004914344,0.0002358566,0.00009419278,0.00002801972,0.00004592761,0.00008895428,0.000008659014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002975648,"about_ca_system_score_gemma":0.0002334922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002880474,"about_ca_topic_score_gemma":0.00004171839,"domain_scores_codex":[0.9992234,0.00001895918,0.0003010654,0.0001954888,0.0001374039,0.0001237561],"domain_scores_gemma":[0.9991094,0.00001414999,0.0001554499,0.000392049,0.0002380297,0.00009090278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007212814,0.00009977276,0.015497,0.00005370128,0.00005746347,0.0003420315,0.002926237,0.000008076368,0.978475,0.0001972063,0.0005719042,0.001699521],"study_design_scores_gemma":[0.0006934336,0.000371295,0.109866,0.0001534216,0.00009116783,0.002462355,0.0002995373,0.0000176518,0.8832543,0.0004850838,0.002187258,0.000118523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946265,0.000364904,0.00003152816,0.0005334717,0.0003653944,0.000418778,0.000005077316,0.00001332332,0.003641029],"genre_scores_gemma":[0.997376,0.00001809703,0.0000883646,0.0003023366,0.00006214261,0.00001150501,0.000006947443,0.00001692136,0.002117676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09522069,"threshold_uncertainty_score":0.2692273,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2160953463","doi":"10.1096/fj.09-143743","title":"New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"College of Natural Resources and Sciences, Humboldt State University; Knut och Alice Wallenbergs Stiftelse; Ontario Ministry of Community and Social Services; GlaxoSmithKline Australia; Institut National Du Cancer; Karolinska Institutet; Ligue Genevoise Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; California Earthquake Authority; Genome Canada; Fondation pour la Recherche Médicale; Hamner Institutes for Health Sciences; Canadian Foundation for AIDS Research; Ontario Innovation Trust; Merck","keywords":"Kinome; Kinase; Threonine; Biochemistry; Casein kinase 1; Serine; Casein kinase 2; Chemistry; Biology; Phosphorylation; Protein kinase A; Cyclin-dependent kinase 2","retraction":null,"screen_n_in":null,"score":{"opus":0.007880076050888899,"gpt":0.2389026084494946,"spread":0.2310225323986057,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111561,0.00009264825,0.0001673328,0.00005251277,0.0001133364,0.00005309253,0.00004113177,0.00004155045,0.00007912591],"category_scores_gemma":[0.00001396965,0.00004928481,0.00004859789,0.00004883143,0.00008519875,0.0001325444,0.00003089284,0.0003535725,4.657749e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001127651,"about_ca_system_score_gemma":0.0001030373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009272114,"about_ca_topic_score_gemma":0.00006620269,"domain_scores_codex":[0.9994295,0.0000183824,0.0001671384,0.00008448082,0.0001854251,0.0001150931],"domain_scores_gemma":[0.9995677,0.00002674624,0.0001015456,0.0001150165,0.00003355908,0.0001553809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000382988,0.00001609956,0.002107662,0.00001628923,0.00008171798,0.00006204962,0.001611269,0.000001865085,0.9646767,0.002666984,0.0004357985,0.02794062],"study_design_scores_gemma":[0.007394708,0.001636811,0.08084652,0.0002734631,0.000287318,0.00867441,0.002066929,0.0001622106,0.8671785,0.02908942,0.002095928,0.0002938034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970626,0.00110255,0.0001709879,0.000862778,0.0006077942,0.00009392007,0.000004296544,0.000004965721,0.00009016626],"genre_scores_gemma":[0.9980373,0.0002760738,0.0003291303,0.0001834564,0.0008966067,4.319133e-7,0.000001094562,0.000009844638,0.0002660099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09749819,"threshold_uncertainty_score":0.2009776,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049877184","doi":"10.1073/pnas.1312739110","title":"Stochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Wellcome Trust; GlaxoSmithKline; Pfizer","keywords":"Kinase; Peptide; Proteolysis; Biophysics; Substrate (aquarium); Chemistry; SH3 domain; Biochemistry; Cell biology; Biology; Enzyme; Proto-oncogene tyrosine-protein kinase Src","retraction":null,"screen_n_in":null,"score":{"opus":0.01884617095176463,"gpt":0.2855362700754397,"spread":0.2666900991236751,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009048736,0.00007193635,0.0002232205,0.0001328082,0.00005310134,0.000007466374,0.0001750184,0.00006861673,0.00003102538],"category_scores_gemma":[0.0008536868,0.00004947502,0.00007570984,0.000554798,0.0002075638,0.0002237371,0.00001999046,0.0001122336,6.687125e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007212875,"about_ca_system_score_gemma":0.00006208754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003266643,"about_ca_topic_score_gemma":4.070279e-7,"domain_scores_codex":[0.9982772,0.000006669608,0.0004106046,0.0001425794,0.001035231,0.0001276667],"domain_scores_gemma":[0.9981127,0.00009597398,0.0008903473,0.000008146126,0.0008645909,0.00002820467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005926904,0.00005444043,0.0002531781,0.0001200593,0.00002311,8.631235e-10,0.0001254128,0.00001575889,0.991501,0.007313828,0.00002859974,0.0005053652],"study_design_scores_gemma":[0.0003155732,0.0003552831,0.0372182,0.0002412493,0.00002031997,0.000001305496,0.0001085125,0.0003747167,0.8956475,0.06567627,0.000001821389,0.00003926735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974201,0.00004681268,0.00007934481,0.001241858,0.000009129451,0.0005659406,0.000007936304,0.000006233638,0.0006226746],"genre_scores_gemma":[0.9985314,0.00001110669,0.001050346,0.0000752596,0.0000351629,0.00004193251,1.249459e-7,0.00000388514,0.0002507846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0958535,"threshold_uncertainty_score":0.2017533,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2155841399","doi":"10.1158/1535-7163.mct-10-0321","title":"PIM Kinase Inhibitors Downregulate STAT3Tyr705 Phosphorylation","year":2010,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network","funders":"National Natural Science Foundation of China; Prostate Cancer Canada; Ontario Institute for Cancer Research","keywords":"Kinase; Cancer research; Cell growth; Cell culture; STAT5; Cancer cell; Downregulation and upregulation; Phosphorylation; Prostate cancer; Biology; Molecular biology; Chemistry; Cancer; Cell biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01396184167469374,"gpt":0.2850547149586722,"spread":0.2710928732839785,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001394878,0.0002400923,0.0002616653,0.00009517276,0.00009301101,0.00004080844,0.000105152,0.0001771784,0.0006771405],"category_scores_gemma":[0.000004042631,0.000217845,0.0001636499,0.0002615851,0.00008275882,0.00006112007,0.00002560173,0.0004156665,0.00002589234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001002741,"about_ca_system_score_gemma":0.0002047676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001941861,"about_ca_topic_score_gemma":0.0001229631,"domain_scores_codex":[0.9986621,0.00002319228,0.0002527342,0.0003392303,0.0003781968,0.0003445043],"domain_scores_gemma":[0.9990655,0.00001160828,0.0001016596,0.0005028734,0.0001528606,0.0001654819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002134358,0.00008939063,0.0005396667,0.00002156625,0.000155885,0.00004527858,0.0002504136,0.00003417836,0.8562217,0.002931117,0.00008978046,0.1394075],"study_design_scores_gemma":[0.002008168,0.0002221689,0.002339106,0.00004521772,0.0001923138,0.00001979424,0.0000383403,0.0006031969,0.8024667,0.002449594,0.1893205,0.0002949324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842172,0.00392762,0.004905315,0.003726061,0.001503067,0.0005822817,0.00002672321,0.0001581915,0.0009534918],"genre_scores_gemma":[0.9915014,0.0004940106,0.001680251,0.005209475,0.0003481677,0.00007354707,0.00002667517,0.00008376255,0.000582708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1892307,"threshold_uncertainty_score":0.8883463,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2149331300","doi":"10.1158/0008-5472.can-06-0284","title":"AAL881, a Novel Small Molecule Inhibitor of RAF and Vascular Endothelial Growth Factor Receptor Activities, Blocks the Growth of Malignant Glioma","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Immunovaccine (Canada)","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Cancer Institute","keywords":"Glioma; Cancer research; Vascular endothelial growth factor; Kinase insert domain receptor; Vascular endothelial growth inhibitor; Receptor; Biology; Basic fibroblast growth factor; Growth factor; Medicine; Vascular endothelial growth factor A; Internal medicine; VEGF receptors","retraction":null,"screen_n_in":null,"score":{"opus":0.03852794546987647,"gpt":0.3107011788455679,"spread":0.2721732333756914,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005575371,0.0001755088,0.0004107245,0.0002429258,0.00009410292,0.00002281063,0.0002016896,0.0001150677,0.0003547947],"category_scores_gemma":[0.00008096974,0.0001201443,0.0001414014,0.0004920638,0.0003791381,0.00005036182,0.0001106651,0.0003431559,0.000001630835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611184,"about_ca_system_score_gemma":0.0004971524,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008254087,"about_ca_topic_score_gemma":0.0002680074,"domain_scores_codex":[0.9979789,0.00009925384,0.0003187656,0.0003466091,0.0008009931,0.0004554808],"domain_scores_gemma":[0.9987591,0.0002045682,0.0001090019,0.0003544805,0.0004532218,0.0001196098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000696343,0.0002051689,0.0007886219,0.000286239,0.0001284644,0.000007640151,0.0004268126,6.412831e-7,0.9931057,0.002966144,0.0007613985,0.0006267949],"study_design_scores_gemma":[0.003047241,0.0005552004,0.001500348,0.0002638483,0.00003366957,0.000009968472,0.0002044025,0.00001897879,0.9915612,0.0003135032,0.002370804,0.0001208569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950702,0.002241128,0.0002478499,0.0007845555,0.000153116,0.0008054688,0.0003092557,0.00001669647,0.0003717789],"genre_scores_gemma":[0.9973662,0.0009276678,0.0002055795,0.00005726576,0.000547814,0.0001157224,0.000008665305,0.00004685924,0.0007241622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00798608,"threshold_uncertainty_score":0.99835,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3108620446","doi":"10.1158/0008-5472.can-20-1876","title":"Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Amgen (Canada); University of Toronto","funders":"New Jersey Commission on Cancer Research; Susan G. Komen; National Cancer Institute; Rutgers Cancer Institute of New Jersey; American Cancer Society; U.S. Department of Defense","keywords":"Colorectal cancer; Cancer research; Metastasis; Medicine; Lung; Wnt signaling pathway; In vivo; Cancer; Lung cancer; Oncology; Biology; Internal medicine; Signal transduction; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0930725144396463,"gpt":0.4532038766076852,"spread":0.3601313621680389,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000402034,0.0001160373,0.000335562,0.00007624868,0.0001036176,0.00003017382,0.00007329472,0.00005608162,0.0006788827],"category_scores_gemma":[0.00005000997,0.00008699032,0.00004034335,0.0003378271,0.0001952433,0.00007612248,0.0001021711,0.0002834245,5.01786e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005573478,"about_ca_system_score_gemma":0.0002292987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004160801,"about_ca_topic_score_gemma":0.00004016843,"domain_scores_codex":[0.9986569,0.0001083967,0.0001748717,0.0003186632,0.000439098,0.0003020508],"domain_scores_gemma":[0.9993302,0.00009305577,0.00005100831,0.00009830253,0.0002129847,0.0002145083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001331765,0.00003908168,0.009086433,0.0008658793,0.0003342989,0.00001548835,0.001824426,0.000003693199,0.8992854,0.0003593598,0.0007411461,0.08611307],"study_design_scores_gemma":[0.002171298,0.0009725163,0.004787439,0.0003379981,0.0001811446,0.000006640991,0.0007424747,0.001202807,0.9773379,0.0001567191,0.01193888,0.0001641605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8928739,0.1016546,0.00006027389,0.004573265,0.00005772622,0.0006157112,0.00003854801,0.00002223491,0.0001037341],"genre_scores_gemma":[0.9865708,0.01230539,0.0003808215,0.0002128739,0.0001787837,0.0002549351,0.000003721064,0.00002932607,0.0000633149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09369695,"threshold_uncertainty_score":0.7433289,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3028963606","doi":"10.1126/sciadv.aba5412","title":"Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8 <sup>+</sup> T cell response in tumor","year":2020,"lang":"en","type":"article","venue":"Science Advances","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"National Natural Science Foundation of China","keywords":"Cytotoxic T cell; Antigen presentation; Endoplasmic reticulum; CD8; Cell biology; MHC class I; Endoplasmic-reticulum-associated protein degradation; Chemistry; Major histocompatibility complex; Antigen; Immune system; Cancer research; Biology; Unfolded protein response; Immunology; Biochemistry; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.01970204954116212,"gpt":0.2986644295108123,"spread":0.2789623799696502,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001463284,0.0002194832,0.000397422,0.0003394179,0.0002546778,0.00007200433,0.0003717558,0.00004059218,0.00009750228],"category_scores_gemma":[0.001020603,0.0001983041,0.00006617597,0.002938564,0.0001156608,0.0004182662,0.00009050334,0.0001970481,0.0001125188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006980629,"about_ca_system_score_gemma":0.0006946441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001580713,"about_ca_topic_score_gemma":0.0002010011,"domain_scores_codex":[0.997326,0.0000943326,0.0003906817,0.0007391572,0.00077799,0.0006717929],"domain_scores_gemma":[0.998712,0.00008444299,0.000109769,0.0002972037,0.000176603,0.0006199532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004609012,0.0002282976,0.001674973,0.00004964274,0.000006970796,0.00009746436,0.009966777,0.005968092,0.9487664,0.0001080067,0.0004607213,0.02806363],"study_design_scores_gemma":[0.003382542,0.005625732,0.004939983,0.0005879953,0.00001593981,0.00001110914,0.005411555,0.004409719,0.9379168,0.0003296938,0.03673765,0.0006312379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790474,0.0004925685,0.001754851,0.01714112,0.0001782523,0.00112202,0.00001642391,0.0001081943,0.0001391391],"genre_scores_gemma":[0.9857597,0.00001806597,0.004463173,0.008900387,0.0001122059,0.0001021728,0.000004196433,0.00002456227,0.0006154801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03627693,"threshold_uncertainty_score":0.8086608,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2095920568","doi":"10.1186/1471-2407-12-45","title":"The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer","year":2012,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary; University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance; Breast Cancer Society of Canada","keywords":"Surgical oncology; Breast cancer; Medicine; Cancer research; Transformation (genetics); Oncology; Cancer; Biology; Internal medicine; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.02105931032037989,"gpt":0.3015690331586462,"spread":0.2805097228382663,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002452924,0.0001469435,0.0001900061,0.00006078364,0.00013302,0.00003182809,0.00006809614,0.00007940395,0.0002655446],"category_scores_gemma":[0.000002791093,0.0001023537,0.00004759479,0.0001744429,0.00004201932,0.0002236215,0.00001587394,0.0001673735,0.000003106106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001781961,"about_ca_system_score_gemma":0.0001335422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002662726,"about_ca_topic_score_gemma":0.00333179,"domain_scores_codex":[0.9990332,0.00002896919,0.0002383208,0.0001668757,0.0001921169,0.0003404937],"domain_scores_gemma":[0.9995638,0.00001288662,0.00007308942,0.0001933794,0.00005071918,0.0001061106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00215691,0.000578558,0.1426371,0.001309598,0.000321582,0.000007890849,0.0155558,0.00001269066,0.5148774,0.01868321,0.001795142,0.3020641],"study_design_scores_gemma":[0.008993254,0.0002749578,0.7922293,0.001403846,0.0001353307,0.00008899229,0.0006371403,0.001026411,0.1362636,0.001623345,0.0566212,0.0007026254],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891196,0.004953185,0.0002114784,0.003817431,0.0002037326,0.00120698,0.00003766002,0.00004949701,0.0004004441],"genre_scores_gemma":[0.9961449,0.0009733448,0.0001100628,0.0005886987,0.0003713926,0.0006715838,0.000006725517,0.00002654841,0.001106774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6495922,"threshold_uncertainty_score":0.4173861,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2156294456","doi":"10.1158/1541-7786.mcr-08-0117","title":"The Fer Tyrosine Kinase Cooperates with Interleukin-6 to Activate Signal Transducer and Activator of Transcription 3 and Promote Human Prostate Cancer Cell Growth","year":2009,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; McGill University","funders":"","keywords":"Prostate cancer; Cancer research; STAT protein; STAT3; LNCaP; Prostate; Biology; Cell growth; Tyrosine phosphorylation; Tyrosine kinase; Cancer; Signal transduction; Medicine; Internal medicine; Cell biology","retraction":null,"screen_n_in":null,"score":{"opus":0.02336487175138026,"gpt":0.3401758736158922,"spread":0.3168110018645119,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003499982,0.0001862198,0.0002672682,0.00009976764,0.0002347464,0.00007995181,0.00009854915,0.0000595943,0.00009572729],"category_scores_gemma":[0.000004953285,0.0001185881,0.00003776497,0.0003537973,0.0001710347,0.0001036939,0.00001831127,0.0003210879,3.806099e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001617925,"about_ca_system_score_gemma":0.0002093561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001869256,"about_ca_topic_score_gemma":0.0005698361,"domain_scores_codex":[0.9984019,0.00009652362,0.0001848708,0.0003920622,0.000507729,0.00041688],"domain_scores_gemma":[0.9991218,0.00001813092,0.00003831064,0.000204143,0.0004012315,0.0002163654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003415426,0.0001111789,0.0001599265,0.000140234,0.00007099131,0.0000311793,0.001882917,0.000006065454,0.9690304,0.0004085628,0.00006997063,0.02467309],"study_design_scores_gemma":[0.002458057,0.002940577,0.002924299,0.0003803454,0.00004036689,0.000007191815,0.0001980467,0.00002843265,0.9889917,0.0002519343,0.001633217,0.0001458374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861617,0.004524012,0.0001937383,0.007604454,0.00002152345,0.001328237,0.00002729717,0.00001646983,0.0001225317],"genre_scores_gemma":[0.9970043,0.001623951,0.00010361,0.0003590648,0.00005173154,0.0002561157,0.00000423526,0.00003909536,0.0005579461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02452725,"threshold_uncertainty_score":0.483588,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2727140374","doi":"10.15252/embj.201796905","title":"Structural basis of divergent cyclin‐dependent kinase activation by Spy1/RINGO proteins","year":2017,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Windsor","funders":"National Cancer Institute; Canadian Institutes of Health Research; Canadian Cancer Society; American Cancer Society","keywords":"Biology; Cyclin; Cyclin-dependent kinase; Genetics; Cell biology; Cell cycle; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.0276046263855965,"gpt":0.3004091936198526,"spread":0.2728045672342561,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003041049,0.00009635169,0.0001779643,0.00003441058,0.0004765701,0.00005985692,0.0002255153,0.00003379995,0.0007195624],"category_scores_gemma":[0.00005356993,0.00005706816,0.0001071165,0.00002271405,0.00004947009,0.0001216323,0.00005135578,0.0002721363,0.000004704723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000790366,"about_ca_system_score_gemma":0.0000633196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002102033,"about_ca_topic_score_gemma":0.00001313545,"domain_scores_codex":[0.9991531,0.00003161522,0.0002101137,0.00009315696,0.0003573605,0.0001546604],"domain_scores_gemma":[0.9990566,0.00001223835,0.0003809579,0.0003584988,0.00009329454,0.00009836894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001317906,0.0001497522,0.005316377,0.00004865523,0.0003745659,0.00004462049,0.001422786,0.0000370664,0.890572,0.0012715,0.002284171,0.09716067],"study_design_scores_gemma":[0.003575426,0.0005567735,0.06916174,0.0002272081,0.0001190581,0.0002629816,0.000301522,0.000229436,0.9182588,0.005058311,0.002094417,0.000154357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946904,0.0001504233,0.0006874113,0.003246454,0.0004397303,0.0002473008,0.000009847525,0.000007536446,0.0005209388],"genre_scores_gemma":[0.9982689,0.0001440779,0.0001942409,0.000167366,0.000533005,0.000005205008,0.000001988635,0.00001294136,0.000672244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09700631,"threshold_uncertainty_score":0.7878703,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2591893930","doi":"10.1016/j.bmc.2017.02.056","title":"Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family","year":2017,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Eshelman Institute for Innovation, University of North Carolina at Chapel Hill; Ministero dello Sviluppo Economico; Cancer Research UK; Novartis Pharma; Canada Foundation for Innovation; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; Fundação de Amparo à Pesquisa do Estado de São Paulo; Genome Canada; European Federation of Pharmaceutical Industries and Associations; AbbVie; Innovative Medicines Initiative; Wellcome; Takeda Pharmaceuticals U.S.A.; Pfizer; Boehringer Ingelheim","keywords":"Kinase; Chemistry; K562 cells; Serine; Threonine; Drug discovery; High-throughput screening; Structure–activity relationship; In vitro; Biochemistry; Pharmacology; Computational biology; Enzyme; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.01314173558473769,"gpt":0.2647492974716209,"spread":0.2516075618868832,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001579934,0.000179108,0.0003148063,0.00001640784,0.0002311,0.00001599675,0.0002067395,0.0001194656,0.000124192],"category_scores_gemma":[0.0002732501,0.0001156696,0.00007908689,0.00008331815,0.0003716768,0.00004251564,0.000121075,0.0002630136,0.000002386929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007731016,"about_ca_system_score_gemma":0.0002773613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001898665,"about_ca_topic_score_gemma":0.000003746576,"domain_scores_codex":[0.9989547,0.00001209515,0.000218816,0.0002676224,0.0003514398,0.0001953941],"domain_scores_gemma":[0.9989107,0.0000255195,0.0002483847,0.0005387155,0.0001252799,0.0001514313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001742084,0.00006696589,0.002084587,0.0001275439,0.00007951516,0.00001939148,0.0004257597,2.170032e-8,0.9930637,0.00009017114,0.0004576899,0.003410398],"study_design_scores_gemma":[0.00163429,0.0001906537,0.05848153,0.0003572297,0.0001011504,0.0001223461,0.0008798761,0.000004843829,0.936295,0.0004969119,0.00132703,0.000109112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898413,0.001793237,0.00002164495,0.003909993,0.0002035251,0.0002095062,0.000008067707,0.00002137894,0.003991313],"genre_scores_gemma":[0.9979057,0.0003100364,0.00005275796,0.0004955673,0.0004755518,0.000007459214,0.000002983858,0.0000224034,0.0007275555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05676872,"threshold_uncertainty_score":0.4716869,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2057953609","doi":"10.1074/jbc.m113.523456","title":"Tudor-SN, a Novel Coactivator of Peroxisome Proliferator-activated Receptor γ Protein, Is Essential for Adipogenesis","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"National Natural Science Foundation of China; National Science Fund for Distinguished Young Scholars; National Science Foundation","keywords":"Adipogenesis; Coactivator; Peroxisome proliferator-activated receptor; Adipocyte; Transcription factor; Biology; Activator (genetics); Cell biology; Ectopic expression; Nuclear receptor; Receptor; Endocrinology; Internal medicine; Molecular biology; Chemistry; Gene; Mesenchymal stem cell; Biochemistry; Adipose tissue; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02436839845327378,"gpt":0.2734400778426291,"spread":0.2490716793893553,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003088061,0.0001762399,0.0006031265,0.00003002912,0.00004173221,0.00001055488,0.000140556,0.0002598959,0.000573452],"category_scores_gemma":[0.0002932218,0.0001147042,0.0003258635,0.0001114704,0.00008105639,0.00004258535,0.00002356445,0.0002189772,0.000001062645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006942014,"about_ca_system_score_gemma":0.0001525171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002488487,"about_ca_topic_score_gemma":4.968655e-8,"domain_scores_codex":[0.9988017,0.00001866829,0.00053994,0.0001981098,0.0002315817,0.0002099975],"domain_scores_gemma":[0.9985694,0.00006747432,0.0005532083,0.0001647883,0.0004510022,0.0001941394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002990299,0.0004629049,0.000304634,0.0001891219,0.000216183,0.000001569223,0.00003313555,4.723326e-7,0.994322,0.0000438859,0.0002790652,0.001156744],"study_design_scores_gemma":[0.003159978,0.001419215,0.0001839069,0.000170578,0.00005626425,0.0000733915,0.00005351222,0.00001896086,0.9849592,0.0001701022,0.009606303,0.0001285428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954829,0.0002283448,0.003053789,0.0006783937,0.00009217743,0.0003241903,0.00005333676,0.0000139609,0.00007286221],"genre_scores_gemma":[0.994805,0.0000410778,0.003675992,0.0003002524,0.0009492838,0.00002965433,0.00001002356,0.00001873212,0.0001700189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00936274,"threshold_uncertainty_score":0.6278898,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1590086377","doi":"10.18632/oncotarget.2330","title":"The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets","year":2014,"lang":"en","type":"article","venue":"Oncotarget","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"BC Cancer Agency","funders":"AstraZeneca","keywords":"PIM1; Kinase; Cancer research; Carcinogenesis; Cancer; Medicine; Biology; Serine; Internal medicine; Phosphorylation; Cell biology","retraction":null,"screen_n_in":null,"score":{"opus":0.01381249360264192,"gpt":0.250293494857433,"spread":0.236481001254791,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002663011,0.0001446932,0.0002767226,0.00006530972,0.0001052451,0.00001569035,0.0001035228,0.00005851748,0.00003190798],"category_scores_gemma":[0.00002333026,0.00008949594,0.00004671094,0.0001904529,0.0001039891,0.00003395292,0.00002262797,0.0001049795,0.000006039772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006470474,"about_ca_system_score_gemma":0.0001693788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006444579,"about_ca_topic_score_gemma":0.0006114131,"domain_scores_codex":[0.999131,0.00004971365,0.0002206657,0.000228373,0.0001485717,0.0002216644],"domain_scores_gemma":[0.9992583,0.0001094925,0.0001023333,0.0003798817,0.00008080551,0.00006923406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002126566,0.0006654561,0.07393566,0.0002098888,0.000308481,0.00001778021,0.001616322,0.00003616246,0.5057923,0.07128357,0.000342982,0.3436649],"study_design_scores_gemma":[0.005166268,0.00321144,0.6941279,0.0002304143,0.0001233849,0.00005609126,0.0005952267,0.0002060855,0.04351074,0.01935914,0.2330409,0.0003724783],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865599,0.006920871,0.001123649,0.002159444,0.00005562419,0.0005752585,0.000009189764,0.00002911064,0.00256693],"genre_scores_gemma":[0.9953755,0.001373045,0.001231036,0.001312235,0.00006809039,0.0001247333,0.000009801219,0.00003007428,0.0004755516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6201922,"threshold_uncertainty_score":0.3649539,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2021678284","doi":"10.1111/febs.13186","title":"Poly(A)<sup>+</sup> mRNA‐binding protein Tudor‐SN regulates stress granules aggregation dynamics","year":2015,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba; Apotex (Canada)","funders":"National Natural Science Foundation of China","keywords":"Stress granule; P-bodies; Messenger RNA; Cytoplasm; RNA-binding protein; Cell biology; Messenger RNP; Cytosol; Gene knockdown; RNA; Poly(A)-binding protein; Biology; Molecular biology; Chemistry; Biochemistry; Enzyme; Gene; Translation (biology)","retraction":null,"screen_n_in":null,"score":{"opus":0.0206096893080361,"gpt":0.2673307204735118,"spread":0.2467210311654757,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004943874,0.0002037777,0.0003137343,0.0002161584,0.0002052747,0.000142459,0.0001396397,0.0001265587,0.0002071499],"category_scores_gemma":[0.00007609563,0.00016667,0.0001406242,0.0002042243,0.00004705349,0.0002498818,0.00003032277,0.0004694304,0.0000362924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000472043,"about_ca_system_score_gemma":0.0002628159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007297154,"about_ca_topic_score_gemma":0.00004864037,"domain_scores_codex":[0.9984148,0.00006824376,0.0003744962,0.0002049371,0.0005713487,0.0003661722],"domain_scores_gemma":[0.9988548,0.00001733046,0.0002434886,0.0002268901,0.000258182,0.0003993678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005812558,0.001353015,0.02405785,0.0004470378,0.001343202,0.001902541,0.01199103,0.001517602,0.05532901,0.0227879,0.008502458,0.8649558],"study_design_scores_gemma":[0.05869637,0.01012395,0.009744508,0.01277325,0.00122803,0.01734871,0.02719157,0.1682155,0.5210975,0.1299114,0.03994826,0.003720999],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991362,0.001933402,0.002934048,0.002152149,0.0003932849,0.000362874,0.00003109471,0.00006816209,0.0007630119],"genre_scores_gemma":[0.9900925,0.0001423431,0.004165513,0.0001494083,0.001355798,0.00001589063,0.00005429838,0.00005693096,0.003967291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8612348,"threshold_uncertainty_score":0.6796605,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2970305079","doi":"10.1007/978-3-030-20301-6_9","title":"Chemotherapy and Inflammatory Cytokine Signalling in Cancer Cells and the Tumour Microenvironment","year":2019,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"NOSM University; Health Sciences North; University of Ottawa; Laurentian University","funders":"","keywords":"Cytokine; Cancer research; Tumor microenvironment; Signalling; Medicine; Immunology; Biology; Cell biology; Tumor cells","retraction":null,"screen_n_in":null,"score":{"opus":0.0351743959748961,"gpt":0.3695553467194962,"spread":0.3343809507446002,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002552472,0.0003428817,0.001553993,0.0001466138,0.0000316829,0.000004421844,0.00007257878,0.0001679852,0.00008202043],"category_scores_gemma":[0.000005016053,0.0001844947,0.00005455532,0.00008739151,0.0006562258,0.00004482862,0.00006707938,0.0003159777,9.701306e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001063376,"about_ca_system_score_gemma":0.00003879592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001348131,"about_ca_topic_score_gemma":0.00004256721,"domain_scores_codex":[0.9986466,0.000099028,0.000480723,0.0004582301,0.0000715371,0.000243903],"domain_scores_gemma":[0.9994262,0.0001788495,0.0001865926,0.0001372936,0.000005185437,0.00006581851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005555212,0.00008253322,0.000251312,0.003275217,0.00009562749,0.00002779405,0.001226631,5.503042e-7,0.02841941,0.0008113767,0.00001416523,0.9652399],"study_design_scores_gemma":[0.009154076,0.0009511363,0.00003169289,0.009463042,0.0001444187,0.0001053025,0.0007980782,0.00001465714,0.002781397,0.0002351163,0.9760342,0.000286919],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009357259,0.9887537,0.000006723722,0.0003317959,0.0002688238,0.001165532,0.000008527503,0.000006238987,0.0001014384],"genre_scores_gemma":[0.00710318,0.9912059,0.00006932562,0.001031798,0.0002722961,0.0002269178,0.00001623188,0.00002865248,0.00004567494],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.97602,"threshold_uncertainty_score":0.7523477,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1545338568","doi":"10.18632/oncotarget.386","title":"PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells","year":2011,"lang":"en","type":"article","venue":"Oncotarget","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Cancer Society Research Institute; Prostate Cancer Canada","keywords":"Gefitinib; Gene knockdown; Kinase; Cancer research; Signal transduction; Cell growth; Biology; Epidermal growth factor receptor; Cancer; Medicine; Cell culture; Cell biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.02453018907467868,"gpt":0.2556227685275627,"spread":0.231092579452884,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000154347,0.00009008665,0.0001945256,0.0000813513,0.00002539573,0.000003969534,0.00002816898,0.00004512625,0.0008497281],"category_scores_gemma":[0.000002599834,0.00007477832,0.00003002322,0.00009954486,0.00002686075,0.00007478183,0.00001455221,0.00009163015,0.000002971498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006111093,"about_ca_system_score_gemma":0.00004027648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003863708,"about_ca_topic_score_gemma":0.00004924426,"domain_scores_codex":[0.9993466,0.00001693117,0.0002033835,0.0001675712,0.0001259231,0.0001395599],"domain_scores_gemma":[0.9996612,0.0000115586,0.00009165951,0.0001332273,0.00004175705,0.0000605995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00059338,0.00009251845,0.008598904,0.0000705843,0.00000643961,0.00001058828,0.003192449,0.000009756367,0.9836906,0.0001775797,0.0003366246,0.003220583],"study_design_scores_gemma":[0.001739504,0.0002445244,0.03034095,0.0003708354,0.000009953427,0.000002182475,0.0002710195,0.0001042832,0.9595072,0.001444136,0.005872034,0.00009337346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968579,0.001709726,0.0001225052,0.00008921015,0.000160215,0.0002957058,0.00001144991,0.0000133156,0.0007399421],"genre_scores_gemma":[0.9946374,0.0008059532,0.003902457,0.00007695725,0.00008143836,0.00002040833,0.000008789545,0.00001693453,0.0004496198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02418339,"threshold_uncertainty_score":0.9303927,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4310070998","doi":"10.3390/microorganisms10122353","title":"Bidirectional Functional Effects of Staphylococcus on Carcinogenesis","year":2022,"lang":"en","type":"review","venue":"Microorganisms","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"Tianjin Medical University; Natural Science Foundation of Tianjin City; National Natural Science Foundation of China","keywords":"Staphylococcus aureus; Microbiology; Staphylococcus; Virulence; Staphylococcus epidermidis; Leukocidin; Biology; Staphylococcal infections; Immunology; Bacteria; Genetics; Methicillin-resistant Staphylococcus aureus; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.04021516851101328,"gpt":0.2923927248636129,"spread":0.2521775563525996,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001375624,0.000409821,0.001514116,0.000385926,0.0001195627,0.0000092043,0.0001315676,0.0002121032,0.006275556],"category_scores_gemma":[0.00002506883,0.0003450015,0.0007789868,0.0004862378,0.00004345438,0.00001474893,0.00006737815,0.0004157639,0.00009289309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004471298,"about_ca_system_score_gemma":0.0007002185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003494287,"about_ca_topic_score_gemma":0.000002291435,"domain_scores_codex":[0.9982304,0.0001030489,0.0004504344,0.0004932424,0.0004768818,0.000245982],"domain_scores_gemma":[0.9988784,0.000238137,0.000281913,0.0004391694,0.00005128829,0.0001111102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001104969,0.0004397372,0.000004278428,0.01708002,0.0008457291,0.0000910296,0.00004398956,5.800266e-7,0.01019932,0.0006947393,0.003154559,0.9673355],"study_design_scores_gemma":[0.0007250577,0.0007672579,0.00004187168,0.00208288,0.001000731,0.0001153517,0.000007976569,1.027303e-7,0.01389383,0.00005955237,0.9810424,0.0002629807],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001936167,0.9963588,0.00008130806,0.00001906876,0.001645864,0.001011327,0.0001480375,0.00006513364,0.0004768948],"genre_scores_gemma":[0.00005056177,0.996704,0.0001285286,0.0002423712,0.0005567755,0.0002296172,0.000327367,0.0001351907,0.001625616],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9778879,"threshold_uncertainty_score":0.9999002,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2767273381","doi":"10.1073/pnas.1711486114","title":"Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Wellcome Trust","keywords":"Piwi-interacting RNA; RasiRNA; Biology; Genetics; Methylation; Gene silencing; Cell biology; RNA; Transposable element; Genome; DNA; Small RNA; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.07791985131445033,"gpt":0.3577563624087978,"spread":0.2798365110943474,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008285969,0.00006542932,0.0001728316,0.00008602021,0.0002275804,0.00001651875,0.0003409461,0.00006133205,0.00004980969],"category_scores_gemma":[0.0005465121,0.0000428131,0.00009261476,0.0001194415,0.0003415217,0.0003046076,0.00004050932,0.00007557926,2.192225e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002737662,"about_ca_system_score_gemma":0.0000369664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001722921,"about_ca_topic_score_gemma":1.518231e-7,"domain_scores_codex":[0.9987434,0.000001900095,0.0002550812,0.0001564367,0.0007527165,0.000090429],"domain_scores_gemma":[0.9987451,0.00006660804,0.0006933556,0.00001130997,0.0004560799,0.00002754435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001441843,0.00003292169,0.002787898,0.0001207266,0.00003920251,1.586641e-9,0.0001634035,0.000004223933,0.9676968,0.01823295,0.0006284082,0.01014931],"study_design_scores_gemma":[0.0006531242,0.0001623809,0.04762854,0.0001329502,0.00003414885,0.00000341062,0.0001114366,0.0007225348,0.8466488,0.1036519,0.0001979479,0.0000528706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928783,0.0001112773,0.00001435011,0.004640275,0.00004450434,0.0003349603,0.0001049454,0.000004706848,0.001866659],"genre_scores_gemma":[0.9970151,0.0000366999,0.002494771,0.000149429,0.00009435966,0.0000149525,7.712189e-7,0.000003720613,0.0001902022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.121048,"threshold_uncertainty_score":0.1750387,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3179068261","doi":"10.1126/scitranslmed.aba4627","title":"Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer","year":2021,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"European Research Council; Imperial Experimental Cancer Medicine Centre; Engineering and Physical Sciences Research Council; National Institute for Health and Care Research; Imperial Oil Limited; NIHR Imperial Biomedical Research Centre; Cancer Treatment and Research Trust; Cancer Research UK; Wellcome Trust; Francis Crick Institute; Medical Research Council; Centro Singular de Investigación de Galicia; University of Kentucky","keywords":"Cancer research; Medicine; Metastasis; Bladder cancer; Lung cancer; Ex vivo; In vivo; Gene silencing; Chemotherapy; Cancer; Pathology; Biology; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01811754971136863,"gpt":0.3265064460286017,"spread":0.3083888963172331,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006823555,0.0001167505,0.0002671828,0.0001406343,0.0001193612,0.00001402615,0.00004875968,0.00002656542,0.0004319272],"category_scores_gemma":[0.00009524465,0.00009276336,0.00002163421,0.0006990694,0.0004080116,0.0001512932,0.00001323361,0.0001288517,2.943247e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005530698,"about_ca_system_score_gemma":0.0004030212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000107838,"about_ca_topic_score_gemma":0.0002982359,"domain_scores_codex":[0.9985183,0.00002132821,0.0002622942,0.0004267332,0.0005408261,0.0002304745],"domain_scores_gemma":[0.9994581,0.00006083609,0.00004885243,0.0001238569,0.000148771,0.0001595799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000320078,0.0001592906,0.02459577,0.000360656,0.00009516248,0.0001453393,0.0061283,0.00007192828,0.8834674,0.01159364,0.0002909671,0.07277149],"study_design_scores_gemma":[0.01766773,0.0004834426,0.70495,0.002719959,0.0005207671,0.0002837179,0.003305512,0.01857264,0.224301,0.01554774,0.01077912,0.0008683403],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9260213,0.03852211,0.001474175,0.03209037,0.0002652814,0.000411224,0.00001752532,0.00002483721,0.001173147],"genre_scores_gemma":[0.9928668,0.001812873,0.003971716,0.0009081584,0.0001579254,0.00002502251,0.00001084877,0.000009550184,0.0002370737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6803542,"threshold_uncertainty_score":0.47293,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2160945991","doi":"10.1155/2014/890141","title":"Phytochemicals: A Multitargeted Approach to Gynecologic Cancer Therapy","year":2014,"lang":"en","type":"review","venue":"BioMed Research International","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Ministry of Education, Science and Technology; National Research Foundation of Korea; Canadian Institutes of Health Research; National Research Foundation","keywords":"Radiation therapy; Medicine; Cancer; Chemotherapy; Oncology; Quality of life (healthcare); Downregulation and upregulation; Bioinformatics; Internal medicine; Cancer research; Biology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.373890066722088,"gpt":0.5595311790408266,"spread":0.1856411123187386,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001253275,0.0003596157,0.001242765,0.001120863,0.00009312994,0.00007771028,0.0007461204,0.0004106527,0.001823314],"category_scores_gemma":[0.0003639589,0.0002458656,0.0004948972,0.0009035189,0.0001327983,0.00003479409,0.0001978141,0.0008556654,0.000326709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001018994,"about_ca_system_score_gemma":0.0007595187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001255672,"about_ca_topic_score_gemma":0.000005033096,"domain_scores_codex":[0.9964525,0.0002445457,0.0005246647,0.0007905556,0.001367299,0.0006204866],"domain_scores_gemma":[0.9979789,0.0003098956,0.0001384678,0.0004896607,0.0006714251,0.0004116837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001367546,0.0004919501,0.000001427268,0.00173479,0.0007180073,0.00001100662,0.0000503778,2.563848e-7,0.000567346,0.000484481,0.04133181,0.9544718],"study_design_scores_gemma":[0.0009496371,0.0002858404,0.000006745945,0.002509548,0.00003800379,0.00002176572,0.00001264599,0.00008736894,0.0001255109,0.0001155235,0.9956058,0.0002416201],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001985098,0.9880077,0.0004105788,0.0008805316,0.001563528,0.00269371,0.0002032975,0.00007753963,0.00614321],"genre_scores_gemma":[0.00003746494,0.9830573,0.002476361,0.0004139263,0.002961935,0.0037079,0.00055403,0.00008612406,0.006704954],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.954274,"threshold_uncertainty_score":0.9999993,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2791600443","doi":"10.1038/s41418-018-0068-9","title":"Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress","year":2018,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Natural Science Foundation of Tianjin City; National Natural Science Foundation of China; National Science Fund for Distinguished Young Scholars; National Science Foundation","keywords":"Chromatin; DNA damage; Radioresistance; Histone; DNA repair; Biology; Cell biology; DNA; Histone acetyltransferase; Acetylation; Molecular biology; Genetics; Cell culture; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01796474141583632,"gpt":0.2726693264076293,"spread":0.254704584991793,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008004377,0.0001543121,0.0002059413,0.00008023557,0.0001482508,0.00005909835,0.00004405045,0.00006621768,0.0002110107],"category_scores_gemma":[0.000005939636,0.0001271446,0.00005082485,0.00006684241,0.00002707901,0.0001024222,0.0000347971,0.00008873239,0.00001117874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005474611,"about_ca_system_score_gemma":0.00004355474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009539619,"about_ca_topic_score_gemma":0.00006851359,"domain_scores_codex":[0.9991003,0.00002550611,0.0001708306,0.0002843772,0.0001879663,0.0002310494],"domain_scores_gemma":[0.9995146,0.00001786293,0.00008704028,0.000189327,0.00006533564,0.0001257891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008108363,0.000506439,0.08745038,0.0006934597,0.0001078182,0.00004207486,0.004464244,7.25575e-7,0.8260388,0.004152795,0.0001392821,0.07559312],"study_design_scores_gemma":[0.004688796,0.0008675687,0.09939691,0.0003531924,0.0001916992,0.00001078922,0.0009071966,0.004941626,0.8835496,0.003580577,0.001123184,0.0003888068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817538,0.0002795396,0.01552349,0.0001689945,0.000327475,0.0003727122,0.00001357187,0.00004656928,0.001513838],"genre_scores_gemma":[0.9976423,0.0001264928,0.0004070243,0.0003317524,0.0003389776,0.00001842163,0.00004192513,0.00002402081,0.001069103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07520431,"threshold_uncertainty_score":0.5184805,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2566301136","doi":"10.1016/j.bbamcr.2016.12.018","title":"Phosphorylation of Tudor-SN, a novel substrate of JNK, is involved in the efficient recruitment of Tudor-SN into stress granules","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"Tianjin Research Program of Application Foundation and Advanced Technology of China; China National Funds for Distinguished Young Scientists; Canadian Institutes of Health Research; Ministry of Education of the People's Republic of China; National Natural Science Foundation of China","keywords":"Phosphorylation; Cell biology; Substrate (aquarium); Stress (linguistics); Chemistry; Materials science; Biology; Philosophy; Ecology; Linguistics","retraction":null,"screen_n_in":null,"score":{"opus":0.07908803463700623,"gpt":0.3596583133167151,"spread":0.2805702786797089,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001277202,0.0002754923,0.0005694545,0.0003982486,0.00005913064,0.00001980224,0.000524624,0.0001564028,0.00004369877],"category_scores_gemma":[0.000062484,0.0001755902,0.0002837071,0.000975408,0.000462004,0.00004529185,0.0001574495,0.0003354323,0.000005522366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001349263,"about_ca_system_score_gemma":0.000382716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008377922,"about_ca_topic_score_gemma":0.00005188312,"domain_scores_codex":[0.996449,0.0003380104,0.0006815233,0.0005451032,0.001501946,0.0004844015],"domain_scores_gemma":[0.997774,0.0002747054,0.0003197498,0.0009773026,0.0005276714,0.0001265727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00113453,0.001846601,0.00003587938,0.0003688276,0.0001083291,0.00001030591,0.003089568,0.00000758216,0.989665,0.002142391,0.00005089179,0.001540123],"study_design_scores_gemma":[0.002926357,0.001277735,0.002814732,0.0005959526,0.00005270652,8.567301e-7,0.0008293379,0.0001972156,0.9902883,0.0007504582,0.00009808753,0.0001682811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945517,0.0005191125,0.0004793868,0.002072739,0.00004960618,0.001755189,0.0001287187,0.00001137351,0.0004321731],"genre_scores_gemma":[0.9984635,0.0005829333,0.0005351347,0.0001086001,0.00003470916,0.0001358523,0.00003835585,0.00004559826,0.00005537541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003911739,"threshold_uncertainty_score":0.7160359,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4251977418","doi":"10.1002/ange.200503468","title":"Ruthenium Half‐Sandwich Complexes Bound to Protein Kinase Pim‐1","year":2006,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institutes of Health; Canadian Institutes of Health Research; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Ruthenium; Chemistry; Stereochemistry; Kinase; Biochemistry; Catalysis","retraction":null,"screen_n_in":null,"score":{"opus":0.01679678274641951,"gpt":0.2629626218363856,"spread":0.2461658390899661,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009997945,0.0001910993,0.0002954502,0.00007129289,0.00009356757,0.00004469151,0.00009385189,0.00008292959,0.001006506],"category_scores_gemma":[0.00001207808,0.0001654237,0.0001057193,0.0002029338,0.00004223289,0.00004687758,0.00003529599,0.0001239813,0.0001073703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009590491,"about_ca_system_score_gemma":0.00007131229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009598315,"about_ca_topic_score_gemma":0.000197423,"domain_scores_codex":[0.9988977,0.000008076746,0.0002034906,0.00030517,0.0002486,0.0003369465],"domain_scores_gemma":[0.9993414,0.00001286578,0.00004781946,0.0003472971,0.00008357341,0.0001670289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002291352,0.0001404778,0.0001376761,0.00005526297,0.00002815583,0.00004793478,0.0001028734,7.41259e-7,0.9806484,0.002038387,0.01596173,0.0006092048],"study_design_scores_gemma":[0.001349958,0.0001906406,0.0005441688,0.00008625719,0.00002998548,0.00001949785,0.00003804899,0.000001597472,0.825664,0.002531911,0.1693751,0.0001688347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683732,0.0009870258,0.0003302145,0.003476525,0.0001529289,0.0007610363,0.0000276985,0.0001481618,0.02574325],"genre_scores_gemma":[0.9819276,0.00001091177,0.001162092,0.001402139,0.0008550304,0.0001226404,0.00007281381,0.00004487677,0.01440194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1549844,"threshold_uncertainty_score":0.9999067,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988455775","doi":"10.2174/187152007784111340","title":"Oncogenic Fusion Tyrosine Kinases as Molecular Targets for Anti-Cancer Therapy","year":2007,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Tyrosine kinase; Kinase; Receptor tyrosine kinase; Cancer research; Cancer therapy; Cancer; Protein-Tyrosine Kinases; Targeted therapy; Fusion protein; Biology; Computational biology; Cell biology; Signal transduction; Genetics; Gene; Recombinant DNA","retraction":null,"screen_n_in":null,"score":{"opus":0.09394851989409721,"gpt":0.4398776877529862,"spread":0.345929167858889,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006602726,0.001178126,0.003540243,0.0002895469,0.0001413804,0.00003573806,0.0005925547,0.000979593,0.004177839],"category_scores_gemma":[0.00007779044,0.0009563024,0.001121812,0.0008010576,0.0002145206,0.00007692355,0.0001106644,0.001125931,0.00003036623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008873914,"about_ca_system_score_gemma":0.001468243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003440599,"about_ca_topic_score_gemma":0.000007030156,"domain_scores_codex":[0.9949088,0.00005827279,0.001385945,0.001408966,0.001116367,0.00112172],"domain_scores_gemma":[0.9975012,0.0001154857,0.0007563205,0.0009143645,0.000266312,0.0004463134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004877952,0.0005813984,0.0001001302,0.02084755,0.0009913268,0.0005289244,0.00007330767,0.000003876892,0.03268324,0.00001473589,0.003774619,0.9399131],"study_design_scores_gemma":[0.00494643,0.0002845812,0.00002730525,0.0223974,0.0009943635,0.0001089624,0.0000435416,0.00001118207,0.1105326,0.00003870929,0.8597969,0.0008179736],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01450456,0.9803017,0.0001904687,0.0002146459,0.001090124,0.002519647,0.0002732482,0.00009222607,0.0008134205],"genre_scores_gemma":[0.001175356,0.9884956,0.0001993757,0.002036369,0.002288405,0.001110928,0.0006862609,0.0002840562,0.003723624],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9390951,"threshold_uncertainty_score":0.9992887,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}