{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":236,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":236,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"5062d7181c35","filters":{"topic":"Cerebrovascular and genetic disorders"}},"results":[{"id":"W4210993281","doi":"10.1016/s1474-4422(03)00305-3","title":"Vascular cognitive impairment","year":2003,"lang":"en","type":"review","venue":"The Lancet Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":1128,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"National Institute of Neurological Disorders and Stroke; European Commission","keywords":"Dementia; Apathy; Vascular dementia; Cognition; Disease; Stroke (engine); Psychology; Medicine; Dementia with Lewy bodies; Cognitive decline; Psychiatry; Pathology","authors":[{"name":"John T. O’Brien","is_ca":false},{"name":"Timo Erkinjuntti","is_ca":false},{"name":"‌Barry Reisberg","is_ca":false},{"name":"Gustavo C. Román","is_ca":false},{"name":"Tohru Sawada","is_ca":false},{"name":"Leonardo Pantoni","is_ca":false},{"name":"John V. Bowler","is_ca":false},{"name":"Clive Ballard","is_ca":false},{"name":"Charles DeCarli","is_ca":false},{"name":"Philip B. Gorelick","is_ca":false},{"name":"Kenneth Rockwood","is_ca":true},{"name":"Alistair Burns","is_ca":false},{"name":"Serge Gauthier","is_ca":false},{"name":"Steven T. DeKosky","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05159096613668682,"gpt":0.3393628152227229,"spread":0.287771849086036,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005760792,0.001495108,0.003120151,0.003065745,0.0003333786,0.0009955007,0.0009641709,0.001155187,0.006682411],"category_scores_gemma":[0.00125101,0.0002366256,0.0006310808,0.003298032,0.0004052262,0.0009050964,0.0008745844,0.001348482,0.002613921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007555154,"about_ca_system_score_gemma":0.001848008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004865672,"about_ca_topic_score_gemma":0.01242969,"domain_scores_codex":[0.999764,0.0000445198,0.00004099807,0.00003406063,0.0000843422,0.00003198294],"domain_scores_gemma":[0.9997073,0.0001105852,0.00006474396,0.00001277162,0.00007587736,0.00002876801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001014022,0.00004658655,0.0001628147,0.01165649,0.000193057,0.0002484226,0.00002277982,0.0001353474,0.000211116,0.0008040852,0.09590492,0.8905129],"study_design_scores_gemma":[0.0002150194,0.000166994,0.003186323,0.01633289,0.001101618,0.004123854,0.00009447892,0.0001270422,0.0002531296,0.003065017,0.9713003,0.00003333184],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009583794,0.9960164,0.00009358153,0.0004184049,0.0006957111,0.000008980797,0.00004302483,0.00001281762,0.002615059],"genre_scores_gemma":[0.001299202,0.994944,0.0002026393,0.0009306088,0.0006073976,0.00001565418,0.00009070495,0.000002016244,0.00190773],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006682411,"threshold_uncertainty_score":0.02235496,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2057164916","doi":"10.1016/j.jalz.2014.10.008","title":"Vascular contributions to cognitive impairment and dementia including Alzheimer's disease","year":2014,"lang":"en","type":"review","venue":"Alzheimer s & Dementia","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":615,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; National Institute on Aging; National Institute of Neurological Disorders and Stroke; Novo Nordisk Fonden","keywords":"Dementia; Vascular dementia; Cognitive impairment; Disease; Cognition; Gerontology; Alzheimer's disease; Stroke (engine); Medicine; Psychology; Psychiatry; Pathology","authors":[{"name":"Heather M. Snyder","is_ca":false},{"name":"Roderick A. Corriveau","is_ca":false},{"name":"Suzanne Craft","is_ca":false},{"name":"James E. Faber","is_ca":false},{"name":"Steven M. Greenberg","is_ca":false},{"name":"David S. Knopman","is_ca":false},{"name":"Bruce T. Lamb","is_ca":false},{"name":"Thomas J. Montine","is_ca":false},{"name":"Maiken Nedergaard","is_ca":false},{"name":"Chris B. Schaffer","is_ca":false},{"name":"Julie A. Schneider","is_ca":false},{"name":"Cheryl L. Wellington","is_ca":true},{"name":"Donna M. Wilcock","is_ca":false},{"name":"Gregory J. Zipfel","is_ca":false},{"name":"Berislav V. Zloković","is_ca":false},{"name":"Lisa J. Bain","is_ca":false},{"name":"Francesca Bosetti","is_ca":false},{"name":"Zorina S. Galis","is_ca":false},{"name":"Walter J. Koroshetz","is_ca":false},{"name":"María C. Carrillo","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03454219415530543,"gpt":0.3444946162812134,"spread":0.309952422125908,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006389843,0.0008304834,0.001373349,0.002876259,0.0003815533,0.001054887,0.0006958542,0.001160583,0.002837717],"category_scores_gemma":[0.0008432214,0.0002627163,0.0005946258,0.003063447,0.0006719288,0.001261357,0.0008843641,0.001584435,0.0009748659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006722375,"about_ca_system_score_gemma":0.001573077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001893446,"about_ca_topic_score_gemma":0.003776757,"domain_scores_codex":[0.9998037,0.0000460881,0.000035221,0.00003079055,0.00006558985,0.000018605],"domain_scores_gemma":[0.999647,0.0001851053,0.00005290823,0.000009288893,0.00007772453,0.00002803027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006755931,0.00006574405,0.0003057774,0.03094,0.0001872416,0.0002517656,0.0001089462,0.000246117,0.0006136929,0.004656026,0.03234417,0.930213],"study_design_scores_gemma":[0.00001996386,0.0000899945,0.002152226,0.01422438,0.0002798391,0.002659199,0.0001820626,0.00006204082,0.0002002191,0.004725265,0.9753751,0.00002973959],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003845584,0.999212,0.00002640471,0.0002241455,0.0001210871,0.000001720991,0.00000531667,0.000002027573,0.0003688639],"genre_scores_gemma":[0.0002781084,0.9993734,0.00003711442,0.00008545549,0.00009961199,0.000001608732,0.000005641633,2.61688e-7,0.0001188935],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002876259,"threshold_uncertainty_score":0.009493113,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1981984722","doi":"10.1038/jcbfm.2012.25","title":"Pathophysiology of the Neurovascular Unit: Disease Cause or Consequence?","year":2012,"lang":"en","type":"review","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":347,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute for Biological Sciences; University of Ottawa","funders":"","keywords":"Pathophysiology; Medicine; Pathology; Disease; Neurovascular bundle; Neuroinflammation; Neuroscience; Pathogenesis; Neurodegeneration; Vascular disease; Biology; Internal medicine","authors":[{"name":"Danica Stanimirovic","is_ca":true},{"name":"Alon Friedman","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04935916509732024,"gpt":0.3102085179041865,"spread":0.2608493528068662,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003932383,0.000937747,0.001811505,0.001781682,0.0003170321,0.001074722,0.0007891566,0.001328029,0.002447572],"category_scores_gemma":[0.0007097868,0.0001940077,0.0003876945,0.001965268,0.0009986702,0.001879973,0.0005817724,0.001384823,0.001418981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006884906,"about_ca_system_score_gemma":0.00129096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001259531,"about_ca_topic_score_gemma":0.001669287,"domain_scores_codex":[0.9998525,0.00002971427,0.00002679705,0.00003113438,0.00004371019,0.00001602306],"domain_scores_gemma":[0.9997442,0.00012923,0.00004114222,0.000007673638,0.00005683878,0.00002088519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009997919,0.00007335856,0.0006459668,0.02287966,0.0001246192,0.001576664,0.0002133976,0.0003760805,0.001923362,0.00753925,0.04097872,0.923569],"study_design_scores_gemma":[0.0000250608,0.0001193582,0.002777535,0.0112344,0.000203845,0.01669526,0.0005359694,0.0001889735,0.0007098346,0.009517752,0.957947,0.00004509022],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001107955,0.9985542,0.000108968,0.0003643128,0.0002386798,0.000002483274,0.00000700587,0.000004038663,0.0006095187],"genre_scores_gemma":[0.0008283813,0.9982468,0.0001270687,0.0001596417,0.0002596965,0.000002986678,0.00001125877,9.075721e-7,0.0003633129],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002447572,"threshold_uncertainty_score":0.00818795,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1975904615","doi":"10.1111/j.1749-6632.2000.tb06343.x","title":"Vascular Factors in Cognitive Impairment‐Where Are We Now?","year":2000,"lang":"en","type":"review","venue":"Annals of the New York Academy of Sciences","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":296,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Library science; Cognitive impairment; University hospital; Medicine; Gerontology; History; Family medicine; Cognition; Psychiatry","authors":[{"name":"Vladimir Hachinski","is_ca":true},{"name":"David G. Muñoz","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1322755887882719,"gpt":0.3916018352218067,"spread":0.2593262464335349,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000942801,0.00103737,0.002812743,0.001683972,0.0003571345,0.001166223,0.001071505,0.001701651,0.002751071],"category_scores_gemma":[0.001082594,0.0002770833,0.0004887892,0.002535137,0.0006832553,0.001736255,0.0005849623,0.002086611,0.001510455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006194072,"about_ca_system_score_gemma":0.001382057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002941203,"about_ca_topic_score_gemma":0.007103753,"domain_scores_codex":[0.9997984,0.00005173664,0.00003574995,0.00002733588,0.00006659044,0.00002020849],"domain_scores_gemma":[0.9995054,0.0002734739,0.00006715226,0.00001146172,0.0001022691,0.00004025408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001543195,0.0001018315,0.0009303732,0.01082684,0.0002071666,0.0005666967,0.00007759412,0.0002532965,0.0003362417,0.002266452,0.08470538,0.8995739],"study_design_scores_gemma":[0.00009863925,0.0001280811,0.005198402,0.009756048,0.0005347043,0.00363777,0.0003160444,0.0001831647,0.0001553655,0.004565764,0.9753845,0.0000415864],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004694471,0.9988347,0.00003103841,0.0004609508,0.0003688392,9.263901e-7,0.000004820658,0.000002272717,0.0002495568],"genre_scores_gemma":[0.0004679023,0.9981737,0.00006623409,0.0003665655,0.0006845958,0.000002198126,0.000008553514,3.78757e-7,0.0002298306],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002941203,"threshold_uncertainty_score":0.009203315,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2615387318","doi":"10.1042/cs20160607","title":"Clinical presentations and epidemiology of vascular dementia","year":2017,"lang":"en","type":"review","venue":"Clinical Science","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":251,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; University of Calgary","funders":"","keywords":"Neuropathology; Dementia; Medicine; Stroke (engine); Vascular dementia; Disease; Population; Etiology; Intensive care medicine; Cardiology; Psychiatry; Internal medicine","authors":[{"name":"Eric E. Smith","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.4225035311365417,"gpt":0.5997058906199292,"spread":0.1772023594833875,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005912554,0.0007398637,0.001312156,0.003396475,0.0002811066,0.001075816,0.0007650017,0.0007706552,0.002520062],"category_scores_gemma":[0.002089109,0.0002200138,0.0008393667,0.00302858,0.0004644005,0.0008557058,0.0005263168,0.001065812,0.0005992622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008467787,"about_ca_system_score_gemma":0.001481066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004358504,"about_ca_topic_score_gemma":0.005114736,"domain_scores_codex":[0.9996206,0.00008381009,0.00009564505,0.00006536717,0.0001042377,0.00003028848],"domain_scores_gemma":[0.9994369,0.0002451089,0.0001421155,0.0000116729,0.0001375818,0.00002657017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001029914,0.00004793584,0.003399045,0.04030982,0.0004121459,0.000418564,0.0002419431,0.0003600824,0.0002345713,0.003369713,0.03341457,0.9176885],"study_design_scores_gemma":[0.00005751922,0.0001625602,0.03171634,0.08156016,0.001658776,0.01573836,0.000673426,0.0003357453,0.0003521079,0.007805846,0.8598413,0.00009799038],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002013185,0.9988263,0.00003956626,0.0001707706,0.00007310335,0.000004342391,0.00003615867,0.000002663775,0.000645726],"genre_scores_gemma":[0.002126571,0.9973436,0.0000856866,0.000111091,0.0001239486,0.000005449624,0.0000594477,8.383388e-7,0.0001434357],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004358504,"threshold_uncertainty_score":0.008666277,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2000632540","doi":"10.1002/gps.2572","title":"Hypertension is a potential risk factor for vascular dementia: systematic review","year":2010,"lang":"en","type":"review","venue":"International Journal of Geriatric Psychiatry","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Alzheimer Society","keywords":"Medicine; Dementia; Vascular dementia; Stroke (engine); Odds ratio; Cochrane Library; Risk factor; Incidence (geometry); PsycINFO; Meta-analysis; MEDLINE; Internal medicine; Epidemiology; Population; Environmental health; Disease","authors":[{"name":"Sally I. Sharp","is_ca":false},{"name":"Dag Aarsland","is_ca":false},{"name":"Sarah Day","is_ca":false},{"name":"Hogne Sønnesyn","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01403504676898712,"gpt":0.3090538136005943,"spread":0.2950187668316072,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01128567,0.00203182,0.01311924,0.006575123,0.0005887426,0.003035106,0.002017292,0.002000041,0.003326814],"category_scores_gemma":[0.03254397,0.001392921,0.02044143,0.006687895,0.000646985,0.001593769,0.001215317,0.001251999,0.0002450492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002055196,"about_ca_system_score_gemma":0.004357473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006255352,"about_ca_topic_score_gemma":0.01331981,"domain_scores_codex":[0.9924616,0.003320418,0.002204674,0.0007375499,0.001055129,0.0002205678],"domain_scores_gemma":[0.9754009,0.0179856,0.004206071,0.0005252894,0.001638306,0.000243752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0008688508,0.00003413921,0.006005551,0.6293275,0.3423367,0.0002004952,0.0001166018,0.0003396986,0.0001825512,0.000132338,0.0007472411,0.01970832],"study_design_scores_gemma":[0.0003040942,0.0002719864,0.008203836,0.09955039,0.8876467,0.0003536099,0.00008878141,0.0001955848,0.0001434357,0.0002112627,0.002995786,0.00003447793],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001865696,0.9973869,0.0001893606,0.0001215745,0.00008769264,0.0001086193,0.0001324109,0.000009788741,0.00009791603],"genre_scores_gemma":[0.06847998,0.9287144,0.001190495,0.0004890595,0.0002423094,0.0004252641,0.0002994366,0.00001197704,0.0001470915],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01311924,"threshold_uncertainty_score":0.05968505,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1824128114","doi":"10.1111/nan.12042","title":"Review: Cerebral amyloid angiopathy, prion angiopathy, <scp>CADASIL</scp> and the spectrum of protein elimination failure angiopathies (<scp>PEFA</scp>) in neurodegenerative disease with a focus on therapy","year":2013,"lang":"en","type":"review","venue":"Neuropathology and Applied Neurobiology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":214,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Medical Research Council; Versus Arthritis; Chinese Academy of Agricultural Sciences; Alzheimer Society","keywords":"Cerebral amyloid angiopathy; Leukoencephalopathy; Angiopathy; CADASIL; Parenchyma; Pathology; Pathogenesis; Amyloid (mycology); Medicine; Neuroscience; Biology; Disease; Dementia","authors":[{"name":"Roxana O. Carare","is_ca":false},{"name":"Cheryl A. Hawkes","is_ca":false},{"name":"M. Jeffrey","is_ca":false},{"name":"Raj N. Kalaria","is_ca":false},{"name":"Roy O. Weller","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01282754542620658,"gpt":0.2426055787642212,"spread":0.2297780333380146,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005158308,0.001452768,0.002093754,0.005050386,0.0004702395,0.001719653,0.001309208,0.002059234,0.008608516],"category_scores_gemma":[0.001538869,0.0003561012,0.0008831793,0.005067989,0.0005241053,0.00241487,0.0008636206,0.002055814,0.004678022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001009997,"about_ca_system_score_gemma":0.001782795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001601173,"about_ca_topic_score_gemma":0.002209271,"domain_scores_codex":[0.9995674,0.00006155137,0.0001247496,0.00007754969,0.0001299968,0.0000386695],"domain_scores_gemma":[0.9991388,0.0002931961,0.0001811563,0.00002445633,0.0002390495,0.0001232801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001377949,0.00007346557,0.0004519721,0.05134632,0.0002997307,0.00130385,0.0001507519,0.0004013015,0.001656469,0.001961263,0.4307532,0.5114638],"study_design_scores_gemma":[0.00001489079,0.00004849193,0.001098066,0.006174087,0.0001341065,0.004284646,0.00007969511,0.00004265195,0.0001120641,0.0005834452,0.9874108,0.00001698105],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000134212,0.9934361,0.0001203097,0.001138382,0.003513969,0.00001279707,0.00007986731,0.00001802221,0.001546382],"genre_scores_gemma":[0.0008014786,0.9923548,0.0002006838,0.001286405,0.003494717,0.00001682574,0.0001953793,0.00000554774,0.001644309],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008608516,"threshold_uncertainty_score":0.02879834,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3094435518","doi":"10.1038/s41467-020-19111-2","title":"Cerebral small vessel disease genomics and its implications across the lifespan","year":2020,"lang":"en","type":"review","venue":"Nature Communications","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; McGill Genome Centre; University of Ottawa","funders":"National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Institute on Aging; Biotechnology and Biological Sciences Research Council; Lundbeckfonden; National Institutes of Health; Agence Nationale de la Recherche; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; Medical Research Council; National Institute for Health and Care Research","keywords":"Mendelian randomization; Genome-wide association study; Confounding; Dementia; Leukoaraiosis; Disease; Medicine; Stroke (engine); White matter; CADASIL; Hyperintensity; Genetic association; Brain size; Bioinformatics; Single-nucleotide polymorphism; Biology; Internal medicine; Genetics; Magnetic resonance imaging; Gene; Genetic variants","authors":[{"name":"Muralidharan Sargurupremraj","is_ca":false},{"name":"Hideaki Suzuki","is_ca":false},{"name":"Xueqiu Jian","is_ca":false},{"name":"Chloé Sarnowski","is_ca":false},{"name":"Tavia E. Evans","is_ca":false},{"name":"Joshua C. Bis","is_ca":false},{"name":"Gudny Eiriksdottir","is_ca":false},{"name":"Saori Sakaue","is_ca":false},{"name":"Natalie Terzikhan","is_ca":false},{"name":"Mohamad Habes","is_ca":false},{"name":"Wei Zhao","is_ca":false},{"name":"Nicola J. Armstrong","is_ca":false},{"name":"Edith Hofer","is_ca":false},{"name":"Lisa R. Yanek","is_ca":false},{"name":"Saskia P. Hagenaars","is_ca":false},{"name":"Erik B. van den Akker","is_ca":false},{"name":"Rebekah McWhirter","is_ca":false},{"name":"Stella Trompet","is_ca":false},{"name":"Aniket Mishra","is_ca":false},{"name":"Yasaman Saba","is_ca":false},{"name":"Claudia L. Satizábal","is_ca":false},{"name":"Grégory Beaudet","is_ca":false},{"name":"Laurent Petit","is_ca":false},{"name":"Ami Tsuchida","is_ca":false},{"name":"Laure Zago","is_ca":false},{"name":"Sabrina Schilling","is_ca":false},{"name":"Sigurður Sigurðsson","is_ca":false},{"name":"Rebecca F. Gottesman","is_ca":false},{"name":"Cora E. Lewis","is_ca":false},{"name":"Neelum T. Aggarwal","is_ca":false},{"name":"Oscar L. López","is_ca":false},{"name":"Jennifer A. Smith","is_ca":false},{"name":"Maria C. Valdés Hernández","is_ca":false},{"name":"Jeroen van der Grond","is_ca":false},{"name":"Margaret J. Wright","is_ca":false},{"name":"Maria J. Knol","is_ca":false},{"name":"Marcus Dörr","is_ca":false},{"name":"Russell Thomson","is_ca":false},{"name":"Constance Bordes","is_ca":false},{"name":"Quentin Le Grand","is_ca":false},{"name":"Marie‐Gabrielle Duperron","is_ca":false},{"name":"Albert V. Smith","is_ca":false},{"name":"David S. Knopman","is_ca":false},{"name":"Pamela J. Schreiner","is_ca":false},{"name":"Denis A. Evans","is_ca":false},{"name":"Jerome I. Rotter","is_ca":false},{"name":"Alexa Beiser","is_ca":false},{"name":"Susana Muñoz Maniega","is_ca":false},{"name":"Marian Beekman","is_ca":false},{"name":"Julian N. Trollor","is_ca":false},{"name":"David J. Stott","is_ca":false},{"name":"Meike W. Vernooij","is_ca":false},{"name":"Katharina Wittfeld","is_ca":false},{"name":"Wiro J. Niessen","is_ca":false},{"name":"Aïcha Soumaré","is_ca":false},{"name":"Eric Boerwinkle","is_ca":false},{"name":"Stephen Sidney","is_ca":false},{"name":"Stephen T. Turner","is_ca":false},{"name":"Gail Davies","is_ca":false},{"name":"Anbupalam Thalamuthu","is_ca":false},{"name":"Uwe Völker","is_ca":false},{"name":"Mark A. van Buchem","is_ca":false},{"name":"R. Nick Bryan","is_ca":false},{"name":"Josée Dupuis","is_ca":false},{"name":"Mark E. Bastin","is_ca":false},{"name":"David Ames","is_ca":false},{"name":"Alexander Teumer","is_ca":false},{"name":"Philippe Amouyel","is_ca":false},{"name":"John B. Kwok","is_ca":false},{"name":"Robin Bülow","is_ca":false},{"name":"Ian J. Deary","is_ca":false},{"name":"Peter R. Schofield","is_ca":false},{"name":"Henry Brodaty","is_ca":false},{"name":"Jiyang Jiang","is_ca":false},{"name":"Yasuharu Tabara","is_ca":false},{"name":"Kazuya Setoh","is_ca":false},{"name":"Susumu Miyamoto","is_ca":false},{"name":"Kazumichi Yoshida","is_ca":false},{"name":"Manabu Nagata","is_ca":false},{"name":"Yoichiro Kamatani","is_ca":false},{"name":"Fumihiko Matsuda","is_ca":false},{"name":"Bruce M. Psaty","is_ca":false},{"name":"David A. Bennett","is_ca":false},{"name":"Philip L. De Jager","is_ca":false},{"name":"Thomas H. Mosley","is_ca":false},{"name":"Perminder S. Sachdev","is_ca":false},{"name":"Reinhold Schmidt","is_ca":false},{"name":"Helen R. Warren","is_ca":false},{"name":"Εvangelos Εvangelou","is_ca":false},{"name":"David‐Alexandre Trégouët","is_ca":false},{"name":"Mariza de Andrade","is_ca":false},{"name":"Saonli Basu","is_ca":false},{"name":"Claudine Berr","is_ca":false},{"name":"Jennifer A. Brody","is_ca":false},{"name":"Daniel I. Chasman","is_ca":false},{"name":"Jean‐François Dartigues","is_ca":false},{"name":"Aaron R. Folsom","is_ca":false},{"name":"Marine Germain","is_ca":false},{"name":"Hugoline G. de Haan","is_ca":false},{"name":"John A. Heit","is_ca":false},{"name":"Jeanine Houwing-Duitermaat","is_ca":false},{"name":"Christopher Kabrhel","is_ca":false},{"name":"Peter Kraft","is_ca":false},{"name":"Grégoire Le Gal","is_ca":true},{"name":"Sara Lindström","is_ca":false},{"name":"Ramin Monajemi","is_ca":false},{"name":"Pierre‐Emmanuel Morange","is_ca":false},{"name":"P.H. Reitsma","is_ca":false},{"name":"Lynda Rose","is_ca":false},{"name":"Frits R. Rosendaal","is_ca":false},{"name":"Noémie Saut","is_ca":false},{"name":"P. Eline Slagboom","is_ca":false},{"name":"David M. Smadja","is_ca":false},{"name":"Nicholas L. Smith","is_ca":false},{"name":"Pierre Suchon","is_ca":false},{"name":"Weihong Tang","is_ca":false},{"name":"Kent D. Taylor","is_ca":false},{"name":"Christophe Tzourio","is_ca":false},{"name":"Marieke C. Visser","is_ca":false},{"name":"Astrid van Hylckama Vlieg","is_ca":false},{"name":"Lu-Chen Weng","is_ca":false},{"name":"Kerri L. Wiggins","is_ca":false},{"name":"Padhraig Gormley","is_ca":false},{"name":"Verneri Anttila","is_ca":false},{"name":"Bendik S. Winsvold","is_ca":false},{"name":"Priit Palta","is_ca":false},{"name":"Tonu Esko","is_ca":false},{"name":"Tune H. Pers","is_ca":false},{"name":"Kai-How Farh","is_ca":false},{"name":"Ester Cuenca-León","is_ca":false},{"name":"Mikko Muona","is_ca":false},{"name":"Nicholas A. Furlotte","is_ca":false},{"name":"Tobias Kurth","is_ca":false},{"name":"Andrés Ingason","is_ca":false},{"name":"George McMahon","is_ca":false},{"name":"Lannie Ligthart","is_ca":false},{"name":"Gisela M. Terwindt","is_ca":false},{"name":"Mikko Kallela","is_ca":false},{"name":"Tobias Freilinger","is_ca":false},{"name":"Caroline Ran","is_ca":false},{"name":"Anine H Stam","is_ca":false},{"name":"Stacy Steinberg","is_ca":false},{"name":"Guntram Borck","is_ca":false},{"name":"Markku Koiranen","is_ca":false},{"name":"Lydia Quaye","is_ca":false},{"name":"Hieab H.H. Adams","is_ca":false},{"name":"Terho Lehtimäki","is_ca":false},{"name":"Antti‐Pekka Sarin","is_ca":false},{"name":"Juho Wedenoja","is_ca":false},{"name":"David A. Hinds","is_ca":false},{"name":"Julie E. Buring","is_ca":false},{"name":"Markus Schürks","is_ca":false},{"name":"Maria Gudlaug Hrafnsdottir","is_ca":false},{"name":"Hreinn Stefánsson","is_ca":false},{"name":"Susan M. Ring","is_ca":false},{"name":"Jouke‐Jan Hottenga","is_ca":false},{"name":"Brenda W. J. H. Penninx","is_ca":false},{"name":"Ville Artto","is_ca":false},{"name":"Mari Kaunisto","is_ca":false},{"name":"Salli Vepsäläinen","is_ca":false},{"name":"Rainer Malik","is_ca":false},{"name":"Andrew C. Heath","is_ca":false},{"name":"Pamela A. F. Madden","is_ca":false},{"name":"Nicholas G. Martin","is_ca":false},{"name":"Grant W. Montgomery","is_ca":false},{"name":"Mitja Kurki","is_ca":false},{"name":"Mart Kals","is_ca":false},{"name":"Reedik Mägi","is_ca":false},{"name":"Kalle Pärn","is_ca":false},{"name":"Eija Hämäläinen","is_ca":false},{"name":"Hailiang Huang","is_ca":false},{"name":"Andrea Byrnes","is_ca":false},{"name":"Lude Franke","is_ca":false},{"name":"Jie Huang","is_ca":false},{"name":"Evie Stergiakouli","is_ca":false},{"name":"Cynthia Sandor","is_ca":false},{"name":"Caleb Webber","is_ca":false},{"name":"M. Zameel Cader","is_ca":false},{"name":"Bertram Müller‐Myhsok","is_ca":false},{"name":"Stefan Schreiber","is_ca":false},{"name":"Thomas Meitinger","is_ca":false},{"name":"Johan G. Eriksson","is_ca":false},{"name":"Veikko Salomaa","is_ca":false},{"name":"Kauko Heikkilä","is_ca":false},{"name":"Elizabeth Loehrer","is_ca":false},{"name":"Andre G. Uitterlinden","is_ca":false},{"name":"Albert Hofman","is_ca":false},{"name":"Cornelia M. van Duijn","is_ca":false},{"name":"Lynn Cherkas","is_ca":false},{"name":"Linda M. Pedersen","is_ca":false},{"name":"Audun Stubhaug","is_ca":false},{"name":"Christopher Sivert Nielsen","is_ca":false},{"name":"Minna Männikkö","is_ca":false},{"name":"Evelin Mihailov","is_ca":false},{"name":"Lili Milani","is_ca":false},{"name":"Hartmut Göbel","is_ca":false},{"name":"Ann-Louise Esserlind","is_ca":false},{"name":"Anne Francke Christensen","is_ca":false},{"name":"Thomas Folkmann Hansen","is_ca":false},{"name":"Thomas Werge","is_ca":false},{"name":"Jaakko Kaprio","is_ca":false},{"name":"Arpo Aromaa","is_ca":false},{"name":"Olli T. Raitakari","is_ca":false},{"name":"M. Arfan Ikram","is_ca":false},{"name":"Tim D. Spector","is_ca":false},{"name":"Marjo-Riitta Järvelin","is_ca":false},{"name":"Andres Metspalu","is_ca":false},{"name":"Christian Kubisch","is_ca":false},{"name":"David P. Strachan","is_ca":false},{"name":"Michel D. Ferrari","is_ca":false},{"name":"Andrea Carmine Belin","is_ca":false},{"name":"Martin Dichgans","is_ca":false},{"name":"Maija Wessman","is_ca":false},{"name":"Arn M. J. M. van den Maagdenberg","is_ca":false},{"name":"John‐Anker Zwart","is_ca":false},{"name":"George Davey Smith","is_ca":false},{"name":"Kari Stefansson","is_ca":false},{"name":"Nicholas Eriksson","is_ca":false},{"name":"Mark J. Daly","is_ca":false},{"name":"Benjamin M. Neale","is_ca":false},{"name":"Jes Olesen","is_ca":false},{"name":"Dale R. Nyholt","is_ca":false},{"name":"Aarno Palotie","is_ca":false},{"name":"Wei Wen","is_ca":false},{"name":"Charles DeCarli","is_ca":false},{"name":"Velandai Srikanth","is_ca":false},{"name":"J. Wouter Jukema","is_ca":false},{"name":"Sharon L. R. Kardia","is_ca":false},{"name":"Yukinori Okada","is_ca":false},{"name":"Bernard Mazoyer","is_ca":false},{"name":"Joanna M. Wardlaw","is_ca":false},{"name":"Paul Nyquist","is_ca":false},{"name":"Karen A. Mather","is_ca":false},{"name":"Hans J. Grabe","is_ca":false},{"name":"Helena Schmidt","is_ca":false},{"name":"Vilmundur Guðnason","is_ca":false},{"name":"W.T. Longstreth","is_ca":false},{"name":"Lenore J. Launer","is_ca":false},{"name":"Mark Lathrop","is_ca":true},{"name":"Sudha Seshadri","is_ca":false},{"name":"Paul M. Matthews","is_ca":false},{"name":"Myriam Fornage","is_ca":false},{"name":"Stéphanie Debette","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05484362402428115,"gpt":0.3693976342280037,"spread":0.3145540102037225,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008989992,0.0007567346,0.001692466,0.001866125,0.0001934502,0.0009760035,0.0007446379,0.001108797,0.003378048],"category_scores_gemma":[0.001314358,0.0002802126,0.0007068746,0.001847174,0.0003747547,0.0009615417,0.0006477883,0.001356193,0.001632522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007839974,"about_ca_system_score_gemma":0.001582273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002145739,"about_ca_topic_score_gemma":0.003449248,"domain_scores_codex":[0.9998214,0.00004223871,0.00003137621,0.00003393464,0.00005043071,0.00002075646],"domain_scores_gemma":[0.9994364,0.0003115731,0.00006885913,0.00001361404,0.0001279006,0.00004155786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001401607,0.00003197812,0.0001968646,0.02922905,0.0002797685,0.0001202747,0.00005474897,0.0003425618,0.0005891418,0.003093509,0.02726116,0.9386607],"study_design_scores_gemma":[0.00005503936,0.0001583792,0.002473735,0.01703359,0.0005821833,0.001015555,0.00008829957,0.0001316657,0.0002592216,0.003839053,0.9743329,0.00003040084],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006137851,0.999231,0.00003430741,0.0002678015,0.00009804835,0.000001858802,0.00001563136,0.000003540902,0.0002864577],"genre_scores_gemma":[0.0004104017,0.9990717,0.00006443408,0.0001746319,0.00007749762,0.000004017471,0.00002313995,8.711588e-7,0.0001732334],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003378048,"threshold_uncertainty_score":0.01130062,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2622764401","doi":"10.1136/svn-2017-000087","title":"Blood pressure gradients in cerebral arteries: a clue to pathogenesis of cerebral small vessel disease","year":2017,"lang":"en","type":"article","venue":"Stroke and Vascular Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Cerebral arteries; Pathogenesis; Cerebral circulation; Cardiology; Medicine; Blood pressure; Blood vessel; Disease; Internal medicine","authors":[{"name":"Pablo Blanco","is_ca":false},{"name":"Lucas O. Müller","is_ca":false},{"name":"J. David Spence","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01065018544454382,"gpt":0.2340431033804253,"spread":0.2233929179358815,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002856666,0.0005852601,0.0004275483,0.0003262245,0.0002001377,0.0007990424,0.0006189891,0.001151408,0.001205514],"category_scores_gemma":[0.0009507005,0.0002045166,0.0002391673,0.0002418484,0.00127715,0.001101587,0.000527786,0.001044158,0.0002403407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003958781,"about_ca_system_score_gemma":0.0004044498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001287822,"about_ca_topic_score_gemma":0.0008326863,"domain_scores_codex":[0.999913,0.00003056521,0.00000395489,0.00001571661,0.0000263391,0.00001047336],"domain_scores_gemma":[0.9997421,0.000131142,0.00005293269,0.00001930598,0.00002647047,0.00002809663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.0006023151,0.0002546026,0.03269293,0.001206591,0.0001444943,0.005191431,0.0009987769,0.4664269,0.06254686,0.344831,0.005448622,0.07965553],"study_design_scores_gemma":[0.00005369654,0.0004742883,0.01216964,0.000250492,0.00009050871,0.002411211,0.0002966226,0.7036637,0.006433475,0.2574217,0.01665154,0.00008312464],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5099512,0.04504296,0.4021404,0.01428253,0.001037543,0.0001394193,0.0004450076,0.0006117558,0.0263491],"genre_scores_gemma":[0.9727936,0.009359712,0.01553589,0.0002631273,0.000358836,0.00003698207,0.00003806619,0.00003434677,0.001579485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001287822,"threshold_uncertainty_score":0.004032791,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2605649001","doi":"10.1093/jnen/nlx009","title":"Collagenosis of the Deep Medullary Veins: An Underrecognized Pathologic Correlate of White Matter Hyperintensities and Periventricular Infarction?","year":2017,"lang":"en","type":"article","venue":"Journal of Neuropathology & Experimental Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":172,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; Occupational Cancer Research Centre; Heart and Stroke Foundation; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Hyperintensity; Medicine; White matter; Leukoaraiosis; Pathology; CADASIL; Pathogenesis; Autopsy; Cardiology; Neuroimaging; Magnetic resonance imaging; Disease; Radiology; Dementia","authors":[{"name":"Julia Keith","is_ca":true},{"name":"Fuqiang Gao","is_ca":true},{"name":"Raza Noor","is_ca":true},{"name":"Alex Kiss","is_ca":true},{"name":"Gayathiri Balasubramaniam","is_ca":true},{"name":"Kelvin Au","is_ca":true},{"name":"Ekaterina Rogaeva","is_ca":true},{"name":"Mario Masellis","is_ca":true},{"name":"Sandra E. Black","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01227391999660609,"gpt":0.2598510914902954,"spread":0.2475771714936894,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002337145,0.0002143447,0.0002035764,0.0004715163,0.0001442059,0.0003248336,0.0001914382,0.0002821927,0.000816661],"category_scores_gemma":[0.0007920446,0.0001288529,0.00005881232,0.0004146777,0.0004235598,0.0003174782,0.0001684379,0.0001688413,0.000152228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000108537,"about_ca_system_score_gemma":0.0001464735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008983103,"about_ca_topic_score_gemma":0.001668615,"domain_scores_codex":[0.9998903,0.00002543455,0.00001051764,0.00003962886,0.00001647793,0.00001765177],"domain_scores_gemma":[0.9994233,0.00008942467,0.0003378984,0.00004014642,0.00004283888,0.00006635749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001367896,0.00001596955,0.9860977,0.00002705066,0.00003312893,0.0008952681,0.0000833842,0.00001854866,0.006636025,0.00004266792,0.00004758975,0.00596591],"study_design_scores_gemma":[0.000004338337,0.0001078383,0.9943334,0.000006345778,0.00001767933,0.004528461,0.000153547,0.00009322367,0.0004847162,0.000102642,0.000165866,0.000002048172],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998645,0.0009910646,0.000121475,0.000035138,0.00000292277,0.000002455721,0.00003381735,0.000003365531,0.0001647997],"genre_scores_gemma":[0.9994463,0.0002805594,0.0001261082,0.00001353393,0.00001767788,0.000001019418,0.0000427469,7.574435e-7,0.00007138558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008983103,"threshold_uncertainty_score":0.002732038,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1983014877","doi":"10.1002/ana.10569","title":"The core and halo of primary progressive aphasia and semantic dementia","year":2003,"lang":"en","type":"review","venue":"Annals of Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Joseph's Hospital; Western University","funders":"U.S. Public Health Service","keywords":"Grossman; Neurology; Primary progressive aphasia; Dementia; Annals; Psychology; Gerontology; Medicine; Psychiatry; Disease; Family medicine; Frontotemporal dementia; Classics; Internal medicine; History","authors":[{"name":"M.‐Marsel Mesulam","is_ca":false},{"name":"Murray Grossman","is_ca":false},{"name":"Argye E. Hillis","is_ca":false},{"name":"Andrew Kertesz","is_ca":true},{"name":"Sandra Weıntraub","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09919271504186171,"gpt":0.3712511304729064,"spread":0.2720584154310447,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006109151,0.001214264,0.002634529,0.004260429,0.0002800187,0.001099601,0.001029653,0.001485435,0.001671959],"category_scores_gemma":[0.001347067,0.0003494181,0.0005482793,0.003175999,0.001065633,0.002119899,0.0007537984,0.001195998,0.0007863311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006401019,"about_ca_system_score_gemma":0.001527211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002256594,"about_ca_topic_score_gemma":0.00631277,"domain_scores_codex":[0.9996959,0.00006402678,0.00008349663,0.00004145953,0.00009138647,0.00002368741],"domain_scores_gemma":[0.9994847,0.0002556109,0.0001156463,0.00001369929,0.00009560186,0.00003473119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001252932,0.00004218414,0.0007659136,0.01791998,0.0001566951,0.002160536,0.0001093589,0.0002215014,0.0006993823,0.001823471,0.04293109,0.9330446],"study_design_scores_gemma":[0.0001137961,0.0001532936,0.006871654,0.01072909,0.0006559771,0.03542949,0.0004357052,0.0002024055,0.0004314179,0.004758576,0.9401554,0.00006308347],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001225017,0.9988325,0.00007536584,0.0001585319,0.0002620083,0.000003038396,0.000008776929,0.000003933552,0.0005332959],"genre_scores_gemma":[0.001808545,0.9963059,0.0002120654,0.0003893618,0.0006645828,0.000006923275,0.00002270648,0.000001558298,0.0005884217],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004260429,"threshold_uncertainty_score":0.0055933,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2099744219","doi":"10.1161/strokeaha.110.588335","title":"Gene Expression Profiling of Blood for the Prediction of Ischemic Stroke","year":2010,"lang":"en","type":"article","venue":"Stroke","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; U.S. Public Health Service; University of Cincinnati; Canadian Institutes of Health Research; MIND Institute, University of California, Davis","keywords":"Medicine; Ischemic stroke; Stroke (engine); Gene expression profiling; Profiling (computer programming); Internal medicine; Gene; Gene expression; Cardiology; Ischemia; Genetics","authors":[{"name":"Boryana Stamova","is_ca":false},{"name":"Huichun Xu","is_ca":false},{"name":"Glen C. Jickling","is_ca":false},{"name":"Cheryl Bushnell","is_ca":false},{"name":"Yingfang Tian","is_ca":false},{"name":"Bradley P. Ander","is_ca":false},{"name":"Xinhua Zhan","is_ca":false},{"name":"Dazhi Liu","is_ca":false},{"name":"Renée J. Turner","is_ca":false},{"name":"Peter G. Adamczyk","is_ca":false},{"name":"Jane Khoury","is_ca":false},{"name":"Arthur Pancioli","is_ca":false},{"name":"Edward C. Jauch","is_ca":false},{"name":"Joseph P. Broderick","is_ca":false},{"name":"Frank R. Sharp","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01013231810759898,"gpt":0.2442789527821874,"spread":0.2341466346745884,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005336161,0.0002797646,0.0003094342,0.0006865446,0.0001273603,0.0003179156,0.0001732413,0.0002798252,0.0007873519],"category_scores_gemma":[0.0008998476,0.0000832576,0.0001314301,0.000428756,0.000206881,0.0001264965,0.0001194021,0.0003224737,0.0003405614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002098219,"about_ca_system_score_gemma":0.0002248589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003839085,"about_ca_topic_score_gemma":0.0005953267,"domain_scores_codex":[0.9997377,0.00009397909,0.00001368965,0.00006948782,0.00005885926,0.00002620624],"domain_scores_gemma":[0.9996846,0.0001525385,0.0000624747,0.00001900214,0.00004606526,0.00003532923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003110817,0.0005947985,0.4078602,0.0002461827,0.0001970835,0.0002482153,0.0001376866,0.001265763,0.5075659,0.0002200883,0.001292697,0.07726061],"study_design_scores_gemma":[0.0001164029,0.002223271,0.858459,0.00006208696,0.0002822436,0.0009695656,0.0001403524,0.01024024,0.1235029,0.0009093827,0.003054504,0.00004012288],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861034,0.003149561,0.007919237,0.0002968839,0.00005904323,0.00008510401,0.001182266,0.00008854795,0.001115931],"genre_scores_gemma":[0.9893601,0.0009355524,0.0080883,0.0001400326,0.00005011231,0.00009559183,0.0008614361,0.00000878762,0.000460126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007873519,"threshold_uncertainty_score":0.002822042,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1969992283","doi":"10.1159/000108661","title":"Rethinking Vascular Dementia (Part 1 of 2)","year":2007,"lang":"en","type":"article","venue":"Cerebrovascular Diseases","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":139,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Medicine; Confusion; Dementia; Vascular dementia; Cognition; Cognitive impairment; Categorization; Stroke (engine); Population; Cognitive decline; Leukoaraiosis; Intensive care medicine; Pathology; Psychiatry; Disease; Psychology","authors":[{"name":"Timo Erkinjuntti","is_ca":true},{"name":"Vladimir Hachinski","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01263877014126427,"gpt":0.2448773246996797,"spread":0.2322385545584155,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005367716,0.0006405169,0.0007469307,0.00136551,0.001386387,0.004734468,0.001696986,0.009867534,0.007033632],"category_scores_gemma":[0.01153179,0.0003383652,0.0006660111,0.0007122681,0.008314847,0.006767764,0.002633316,0.009676772,0.002701201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001606453,"about_ca_system_score_gemma":0.002882894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003155621,"about_ca_topic_score_gemma":0.007789229,"domain_scores_codex":[0.9976172,0.0009855943,0.0002784348,0.0002915474,0.00063067,0.0001966082],"domain_scores_gemma":[0.9927805,0.003762207,0.0003863703,0.0005377986,0.001583983,0.0009491321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009439934,0.00007696667,0.0021915,0.0009293825,0.00003193877,0.001434712,0.002067403,0.0001514748,0.001338632,0.04720473,0.6935922,0.2508866],"study_design_scores_gemma":[0.00001174817,0.00004948384,0.003313152,0.0009202817,0.00002113055,0.002537119,0.0006987453,0.0001015446,0.0002181924,0.02383229,0.9682657,0.00003048061],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.004256523,0.1644847,0.003615713,0.5683126,0.2246588,0.00005274686,0.0001012726,0.0001481061,0.03436951],"genre_scores_gemma":[0.05613926,0.1448216,0.007040688,0.4472339,0.2964141,0.0002238868,0.0001860637,0.000216444,0.04772409],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.009867534,"threshold_uncertainty_score":0.02838749,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988600763","doi":"10.1002/ajmg.a.32080","title":"Cerebroretinal microangiopathy with calcifications and cysts (CRMCC)","year":2007,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part A","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Microangiopathy; Calcification; Pathology; Leukoencephalopathy; Pathogenesis; Medicine; Coats' disease; Calcinosis; Retinal; Ophthalmology; Disease","authors":[{"name":"Tracy A. Briggs","is_ca":false},{"name":"Ghada M. H. Abdel‐Salam","is_ca":false},{"name":"Maryagnes R. Balicki","is_ca":true},{"name":"Peter Baxter","is_ca":false},{"name":"Enrico Bertini","is_ca":false},{"name":"Nick Bishop","is_ca":false},{"name":"B H Browne","is_ca":false},{"name":"David Chitayat","is_ca":true},{"name":"W.K. Chong","is_ca":false},{"name":"Maha M. Eid","is_ca":false},{"name":"William Halliday","is_ca":true},{"name":"Imelda Hughes","is_ca":false},{"name":"A. Klusmann‐Koy","is_ca":false},{"name":"Mary Kurian","is_ca":false},{"name":"Ken K. Nischal","is_ca":false},{"name":"Gillian Rice","is_ca":false},{"name":"John B.P. Stephenson","is_ca":false},{"name":"R. Surtees","is_ca":false},{"name":"J F Talbot","is_ca":false},{"name":"Nasrin Tehrani","is_ca":true},{"name":"John Tolmie","is_ca":false},{"name":"Carmel Toomes","is_ca":false},{"name":"Marjo S. van der Knaap","is_ca":false},{"name":"Yanick J. Crow","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007292027274560122,"gpt":0.2801018571273221,"spread":0.272809829852762,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001739933,0.0006108769,0.000331903,0.001046043,0.0005390923,0.0003861542,0.0002650589,0.000470712,0.001528074],"category_scores_gemma":[0.00107702,0.0002094495,0.0001922689,0.000558456,0.000700635,0.0002486783,0.0005524218,0.0005371729,0.0003372406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001821965,"about_ca_system_score_gemma":0.0003051126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0023421,"about_ca_topic_score_gemma":0.003169814,"domain_scores_codex":[0.9998482,0.00001511683,0.00001815077,0.00003790792,0.00005051495,0.00003004486],"domain_scores_gemma":[0.9993941,0.0001584308,0.0002209499,0.00004556903,0.00005582984,0.0001250349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0003496754,0.0001138975,0.2169406,0.000359797,0.0001476087,0.6300827,0.001553987,0.0002629122,0.07693824,0.001346841,0.002403416,0.06950042],"study_design_scores_gemma":[0.00002299608,0.0001164862,0.08375576,0.00002171543,0.0000612455,0.9083322,0.0001524307,0.0002606676,0.005109,0.0002239092,0.001926634,0.00001687689],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871975,0.001635185,0.002293669,0.000232179,0.00003946954,0.00005386158,0.0002088309,0.0001981413,0.00814116],"genre_scores_gemma":[0.9968929,0.0005396794,0.001669402,0.0001013362,0.00004013447,0.000006719999,0.0001001415,0.00001803889,0.0006315791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0023421,"threshold_uncertainty_score":0.005111933,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3116867483","doi":"10.1016/j.semcdb.2020.12.011","title":"Role of Notch signaling in neurovascular aging and Alzheimer’s disease","year":2020,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Alzheimer's Association","keywords":"Notch signaling pathway; CADASIL; Neuroscience; Hes3 signaling axis; Neurovascular bundle; Neuropathology; Mechanism (biology); Dementia; Signal transduction; Disease; Biology; Medicine; Pathology; Genetics; Anatomy","authors":[{"name":"Arunima Kapoor","is_ca":false},{"name":"Daniel A. Nation","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01859601566947461,"gpt":0.2786955826097935,"spread":0.2600995669403189,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004470579,0.0006418105,0.0008813064,0.00184072,0.0002739911,0.0007919348,0.0006547649,0.0009448522,0.002597074],"category_scores_gemma":[0.0004687647,0.00016383,0.0003411643,0.001700045,0.0004130534,0.0009808765,0.0006845634,0.001302159,0.001416823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005704054,"about_ca_system_score_gemma":0.001137652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001008642,"about_ca_topic_score_gemma":0.001602522,"domain_scores_codex":[0.9998952,0.00001884191,0.000018559,0.00001676638,0.00003768538,0.00001294192],"domain_scores_gemma":[0.999843,0.00006003203,0.00002154023,0.000005034393,0.00004892588,0.00002151621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007838516,0.00004860223,0.0001642609,0.01198625,0.0000705224,0.0003515473,0.00007523598,0.0003854645,0.001573183,0.003895427,0.02483604,0.9565352],"study_design_scores_gemma":[0.00001784107,0.00007636369,0.001108567,0.004997495,0.0001135128,0.002452636,0.00008352094,0.00009920798,0.0004645981,0.003816586,0.9867507,0.00001908988],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008383562,0.9989901,0.00005103188,0.0001717417,0.0001167492,0.000001623933,0.00000657365,0.000003545565,0.0005747718],"genre_scores_gemma":[0.0005729211,0.9987418,0.00008573884,0.0001186248,0.0001098472,0.00000242673,0.0000134684,6.056721e-7,0.0003546336],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002597074,"threshold_uncertainty_score":0.008688033,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2566072324","doi":"10.1002/ana.24840","title":"Genetic variation at 16q24.2 is associated with small vessel stroke","year":2016,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Medical Research Council; National Institutes of Health; Vlaamse regering; Fonds Wetenschappelijk Onderzoek; Deutsche Forschungsgemeinschaft; King's College London; California Department of Fish and Game; University of Cambridge; Cambridge University Hospitals; Stroke Association; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Wellcome Trust; H2020 European Research Council; South London and Maudsley NHS Foundation Trust; Wellcome","keywords":"Genome-wide association study; Odds ratio; Stroke (engine); Medicine; Single-nucleotide polymorphism; Intracerebral hemorrhage; Population; Confidence interval; Internal medicine; Genetic association; Biology; Genetics; Genotype; Gene; Subarachnoid hemorrhage","authors":[{"name":"Matthew Traylor","is_ca":false},{"name":"Rainer Malik","is_ca":false},{"name":"Mike A. Nalls","is_ca":false},{"name":"Ioana Cotlarciuc","is_ca":false},{"name":"Farid Radmanesh","is_ca":false},{"name":"Guðmar Þorleifsson","is_ca":false},{"name":"Ken B. Hanscombe","is_ca":false},{"name":"Carl D. Langefeld","is_ca":false},{"name":"Danish Saleheen","is_ca":false},{"name":"Natalia S. Rost","is_ca":false},{"name":"İdil Yet","is_ca":false},{"name":"Tim D. Spector","is_ca":false},{"name":"Jordana T. Bell","is_ca":false},{"name":"Eilís Hannon","is_ca":false},{"name":"Jonathan Mill","is_ca":false},{"name":"Ganesh Chauhan","is_ca":false},{"name":"Stéphanie Debette","is_ca":false},{"name":"Joshua C. Bis","is_ca":false},{"name":"W.T. Longstreth","is_ca":false},{"name":"M. Arfan Ikram","is_ca":false},{"name":"Lenore J. Launer","is_ca":false},{"name":"Sudha Seshadri","is_ca":false},{"name":"Monica Anne Hamilton‐Bruce","is_ca":false},{"name":"Jordi Jiménez-Conde","is_ca":false},{"name":"John W. Cole","is_ca":false},{"name":"Reinhold Schmidt","is_ca":false},{"name":"Agnieszka Słowik","is_ca":false},{"name":"Robin Lemmens","is_ca":false},{"name":"Olle Melander","is_ca":false},{"name":"Raji P. Grewal","is_ca":false},{"name":"Ralph L. Sacco","is_ca":false},{"name":"Tatjana Rundek","is_ca":false},{"name":"Kathryn M. Rexrode","is_ca":false},{"name":"Donna K. Arnett","is_ca":false},{"name":"Julie A. Johnson","is_ca":false},{"name":"Oscar Benavente","is_ca":true},{"name":"Sylvia Wasssertheil‐Smoller","is_ca":false},{"name":"Jin‐Moo Lee","is_ca":false},{"name":"Sara L. Pulit","is_ca":false},{"name":"Quenna Wong","is_ca":false},{"name":"Stephen S. Rich","is_ca":false},{"name":"Paul I. W. de Bakker","is_ca":false},{"name":"Patrick F. McArdle","is_ca":false},{"name":"Daniel Woo","is_ca":false},{"name":"Christopher D. Anderson","is_ca":false},{"name":"Huichun Xu","is_ca":false},{"name":"Laura Heitsch","is_ca":false},{"name":"Myriam Fornage","is_ca":false},{"name":"Christina Jern","is_ca":false},{"name":"Unnur Þorsteinsdóttir","is_ca":false},{"name":"Sólveig Grétarsdóttir","is_ca":false},{"name":"Cathryn M. Lewis","is_ca":false},{"name":"Pankaj Sharma","is_ca":false},{"name":"Cathie Sudlow","is_ca":false},{"name":"Peter M. Rothwell","is_ca":false},{"name":"Giorgio B. Boncoraglio","is_ca":false},{"name":"Vincent Thijs","is_ca":false},{"name":"Christopher Levi","is_ca":false},{"name":"James F. Meschia","is_ca":false},{"name":"Jonathan Rosand","is_ca":false},{"name":"Steven J. Kittner","is_ca":false},{"name":"Braxton D. Mitchell","is_ca":false},{"name":"Martin Dichgans","is_ca":false},{"name":"Bradford B. Worrall","is_ca":false},{"name":"Hugh S. Markus","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03447953626562053,"gpt":0.2604154517572216,"spread":0.2259359154916011,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009735405,0.001175037,0.0008140834,0.001106816,0.0004032097,0.00072023,0.0006183028,0.0008083693,0.00363913],"category_scores_gemma":[0.003616377,0.0003826011,0.001402537,0.002014125,0.0004878267,0.0002078458,0.0004322701,0.0005327668,0.0003074879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000176734,"about_ca_system_score_gemma":0.0001948549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003419633,"about_ca_topic_score_gemma":0.002711881,"domain_scores_codex":[0.9992293,0.0001726581,0.00007755051,0.0003523647,0.000106942,0.00006114343],"domain_scores_gemma":[0.9979526,0.0006872999,0.0009403724,0.0001609406,0.0001006094,0.0001580292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0031735,0.00008884819,0.9483221,0.0002458348,0.00477523,0.002544248,0.0002692546,0.001543752,0.02806529,0.0002667265,0.0007760881,0.009929007],"study_design_scores_gemma":[0.0002391479,0.0002290197,0.9927376,0.00005019413,0.0012215,0.001763316,0.00005986878,0.0009428806,0.001151384,0.0006510285,0.00093163,0.00002237325],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939267,0.002695243,0.0009855647,0.0002473193,0.00005823155,0.00001746249,0.001496075,0.00006944365,0.000504045],"genre_scores_gemma":[0.9972878,0.0007985512,0.0005781385,0.00005769997,0.00007065032,0.00002240573,0.0007622337,0.00001741907,0.000405299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00363913,"threshold_uncertainty_score":0.01217413,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2233600556","doi":"10.1158/1078-0432.ccr-15-2360","title":"Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted Therapy","year":2016,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Prevention of Organ Failure; University of British Columbia","funders":"Canadian Cancer Society Research Institute; Vancouver Coastal Health Research Institute; National Health Research Institutes; Canadian Urological Association; Urology Care Foundation","keywords":"Cancer research; Notch signaling pathway; Bladder cancer; Epithelial–mesenchymal transition; Oncogene; Cancer; Metastasis; Biology; Gene silencing; Tumor progression; Carcinogenesis; Cell cycle; Medicine; Internal medicine; Signal transduction; Cell biology","authors":[{"name":"Tetsutaro Hayashi","is_ca":true},{"name":"Kilian M. Gust","is_ca":true},{"name":"Alexander W. Wyatt","is_ca":true},{"name":"Akihiro Goriki","is_ca":true},{"name":"Wolfgang Jäger","is_ca":true},{"name":"Shannon Awrey","is_ca":true},{"name":"Na Li","is_ca":true},{"name":"Htoo Zarni Oo","is_ca":true},{"name":"Manuel Altamirano-Dimas","is_ca":true},{"name":"Ralph Buttyan","is_ca":true},{"name":"Ladan Fazli","is_ca":true},{"name":"Akio Matsubara","is_ca":false},{"name":"Peter C. Black","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3062541810693193,"gpt":0.5504529491950023,"spread":0.244198768125683,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004925247,0.0002129562,0.0003156908,0.0002052432,0.0002709621,0.0009622588,0.0002894193,0.0005004053,0.002517637],"category_scores_gemma":[0.0003332893,0.0001033729,0.0002461812,0.0003179031,0.0004517559,0.0007473347,0.0004835358,0.0008954689,0.0003896572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007865588,"about_ca_system_score_gemma":0.0007495068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005289947,"about_ca_topic_score_gemma":0.0006654261,"domain_scores_codex":[0.9998459,0.00002950098,0.00001170655,0.0000313841,0.000052017,0.00002954478],"domain_scores_gemma":[0.9998388,0.00002887788,0.0000405908,0.00002040028,0.00003312511,0.00003814095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002171167,0.0001376292,0.0127264,0.001846264,0.0001535807,0.001402594,0.0002800341,0.001911152,0.6875575,0.01637623,0.00545512,0.2699822],"study_design_scores_gemma":[0.0002161318,0.002119615,0.04286862,0.0009663165,0.0004524734,0.01435024,0.001092103,0.009804252,0.642985,0.02035468,0.2646894,0.0001010553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6915801,0.2327495,0.02494955,0.02414372,0.001389289,0.0000752983,0.0006599131,0.0002580863,0.02419457],"genre_scores_gemma":[0.9462424,0.03813135,0.003088024,0.002572178,0.0002221352,0.00002691307,0.0001782265,0.00002997692,0.009508865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002517637,"threshold_uncertainty_score":0.008422375,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1986308658","doi":"10.1159/000054785","title":"The Incidence of Vascular Dementia in Canada: A Comparison with Europe and East Asia","year":2001,"lang":"en","type":"article","venue":"Neuroepidemiology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Health and Social Services Centre University Institute of Geriatrics of Sherbrooke; Université de Sherbrooke","funders":"","keywords":"Incidence (geometry); Dementia; Medicine; Vascular dementia; Disease; Demography; Gerontology; Pathology","authors":[{"name":"Marie‐France Dubois","is_ca":true},{"name":"Réjean Hébert","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01695348304834445,"gpt":0.2538728534064396,"spread":0.2369193703580952,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007571551,0.0004290747,0.0005407888,0.005644226,0.001333585,0.001746205,0.0007749493,0.0004920221,0.001670274],"category_scores_gemma":[0.002950153,0.0002415368,0.0008463564,0.01311573,0.0006142845,0.0004700137,0.0008724153,0.0005917219,0.0001799365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01817285,"about_ca_system_score_gemma":0.01901261,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9797081,"about_ca_topic_score_gemma":0.9789949,"domain_scores_codex":[0.9988812,0.0000735889,0.0001140042,0.0001283514,0.0005369099,0.0002660169],"domain_scores_gemma":[0.997468,0.0001522724,0.00053814,0.00004845024,0.001346484,0.0004466607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003192796,0.00003605253,0.9728032,0.0002717566,0.0003883293,0.0002534048,0.0006110105,0.0002920042,0.0001738982,0.0005522869,0.001543935,0.02275481],"study_design_scores_gemma":[0.00001035989,0.00002868095,0.9968778,0.0000610564,0.0001251858,0.0002185338,0.0007301117,0.0002487703,0.00005145909,0.00006411875,0.001570566,0.00001334941],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9541097,0.02819679,0.0003069549,0.001422595,0.0000890235,0.00004427215,0.006566864,0.00004491812,0.009218894],"genre_scores_gemma":[0.9853531,0.01102237,0.000364277,0.0001398887,0.00003880462,0.00001266717,0.002369665,0.00001157612,0.0006877779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02029186,"threshold_uncertainty_score":0.1318538,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2056600158","doi":"10.1007/s11916-005-0039-y","title":"Migraine and white matter hyperintensities","year":2005,"lang":"en","type":"review","venue":"Current Pain and Headache Reports","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Hyperintensity; CADASIL; Medicine; Leukoencephalopathy; White matter; Migraine; Pathology; Encephalopathy; Stroke (engine); Lactic acidosis; Magnetic resonance imaging; Cardiology; Disease; Internal medicine; Radiology","authors":[{"name":"A. J. Porter","is_ca":true},{"name":"Jonathan P. Gladstone","is_ca":true},{"name":"David W. Dodick","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04064383515770537,"gpt":0.33479881265302,"spread":0.2941549774953147,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005107007,0.001149846,0.002154212,0.005793456,0.0002625002,0.0010947,0.0008807678,0.001219354,0.003868601],"category_scores_gemma":[0.001262851,0.0004094357,0.000463508,0.005364052,0.000536839,0.001948269,0.0006734671,0.0009855889,0.001617539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004550343,"about_ca_system_score_gemma":0.001195272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002069778,"about_ca_topic_score_gemma":0.006032981,"domain_scores_codex":[0.9997255,0.00003717795,0.0000863684,0.00004520319,0.00008391055,0.00002172986],"domain_scores_gemma":[0.9993381,0.000261189,0.0002223217,0.00001795285,0.0001190181,0.00004139911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009745751,0.00006977766,0.0008127646,0.02387737,0.0002137863,0.001469401,0.00007529338,0.0002453814,0.001093837,0.000598015,0.03881844,0.9326285],"study_design_scores_gemma":[0.00008219875,0.000185836,0.008459719,0.01562502,0.001171851,0.01879881,0.0002487296,0.0001925826,0.0005878966,0.001442625,0.9531496,0.00005514633],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001949908,0.9983789,0.00006964677,0.0001872967,0.0002338571,0.000005560893,0.00002435123,0.000006510327,0.0008988712],"genre_scores_gemma":[0.001032584,0.9972882,0.0001912423,0.0002500224,0.0004774203,0.000005701513,0.00004622621,0.000001152735,0.00070737],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005793456,"threshold_uncertainty_score":0.01294178,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4291583316","doi":"10.1001/jamaneurol.2022.2262","title":"Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE)","year":2022,"lang":"en","type":"review","venue":"JAMA Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Institute on Aging; National Institutes of Health; National Institute of Neurological Disorders and Stroke; Medical Research Council; National Institute for Health and Care Research; British Heart Foundation; Wellcome Trust","keywords":"CADASIL; Medicine; Clinical trial; Cerebral amyloid angiopathy; Lacunar stroke; Randomized controlled trial; Disease; Pathology; Dementia; Bioinformatics; Intensive care medicine; Internal medicine; Ischemic stroke; Biology","authors":[{"name":"Hugh S. Markus","is_ca":false},{"name":"Wiesje M. van der Flier","is_ca":false},{"name":"Eric E. Smith","is_ca":true},{"name":"Philip M. Bath","is_ca":false},{"name":"Geert Jan Biessels","is_ca":false},{"name":"Emily M. Briceño","is_ca":false},{"name":"Amy Brodtman","is_ca":false},{"name":"Hugues Chabriat","is_ca":false},{"name":"Christopher Chen","is_ca":false},{"name":"Frank‐Erik de Leeuw","is_ca":false},{"name":"Marco Egle","is_ca":false},{"name":"Aravind Ganesh","is_ca":true},{"name":"Marios K. Georgakis","is_ca":false},{"name":"Rebecca F. Gottesman","is_ca":false},{"name":"Sun U. Kwon","is_ca":false},{"name":"Lenore J. Launer","is_ca":false},{"name":"Vincent Mok","is_ca":false},{"name":"John T. O’Brien","is_ca":false},{"name":"Lois Ottenhoff","is_ca":false},{"name":"Sarah T. Pendlebury","is_ca":false},{"name":"Edo Richard","is_ca":false},{"name":"Perminder S. Sachdev","is_ca":false},{"name":"Reinhold Schmidt","is_ca":false},{"name":"Melanie J. Springer","is_ca":false},{"name":"Stefan Tiedt","is_ca":false},{"name":"Joanna M. Wardlaw","is_ca":false},{"name":"Ana Verdelho","is_ca":false},{"name":"Alastair J.S. Webb","is_ca":false},{"name":"David J. Werring","is_ca":false},{"name":"Marco Duering","is_ca":false},{"name":"Deborah A. Levine","is_ca":false},{"name":"Martin Dichgans","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3187738034552652,"gpt":0.4913879232458689,"spread":0.1726141197906038,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.7416566,0.006899067,0.01238355,0.01421406,0.007427339,0.02416775,0.01638045,0.04146347,0.01199631],"category_scores_gemma":[0.658188,0.006060003,0.02051483,0.009149581,0.01808983,0.01048689,0.02122224,0.03703124,0.007348727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.03021278,"about_ca_system_score_gemma":0.1353494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01083175,"about_ca_topic_score_gemma":0.009498028,"domain_scores_codex":[0.1557592,0.7246221,0.06944305,0.01243367,0.03125482,0.006487001],"domain_scores_gemma":[0.2177428,0.6063794,0.04413022,0.031886,0.0805907,0.01927082],"domain_codex":"methods","domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001627172,0.0002897184,0.001631495,0.05365927,0.003527466,0.0007967414,0.005966017,0.01611001,0.000837559,0.5752725,0.1254616,0.2148204],"study_design_scores_gemma":[0.004538244,0.001190461,0.001695214,0.09458564,0.003061985,0.0004570027,0.0009350494,0.009765401,0.0007289592,0.3408689,0.5416812,0.0004918523],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"protocol","genre_scores_codex":[0.001378871,0.03707138,0.511857,0.2845572,0.01390244,0.108393,0.003655883,0.001842572,0.03734168],"genre_scores_gemma":[0.01395806,0.006871247,0.8070761,0.04970006,0.002739322,0.1148243,0.001408718,0.0002263893,0.003195777],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.7416566,"threshold_uncertainty_score":0.3185835,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2760436846","doi":"10.1212/wnl.0000000000004560","title":"<i>COL4A2</i> is associated with lacunar ischemic stroke and deep ICH","year":2017,"lang":"en","type":"review","venue":"Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute; Health Sciences Centre","funders":"National Center for Advancing Translational Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Institute on Aging; Stiftung zur Erforschung der Vaskulären Demenz; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Bundesministerium für Bildung und Forschung; National Institute of Diabetes and Digestive and Kidney Diseases; Lunds Universitet; Deutsche Forschungsgemeinschaft; Cambridge University Hospitals; Fondation Leducq; STROKE-Riksförbundet; European Commission; University of Cambridge; National Heart, Lung, and Blood Institute; Canadian Stroke Network","keywords":"Lacunar stroke; Odds ratio; Single-nucleotide polymorphism; Linkage disequilibrium; Medicine; Confidence interval; SNP; Stroke (engine); Intracerebral hemorrhage; Locus (genetics); Internal medicine; Ischemic stroke; Cardiology; Pathology; Genotype; Genetics; Biology; Gene; Ischemia","authors":[{"name":"Kristiina Rannikmäe","is_ca":true},{"name":"Vhinoth Sivakumaran","is_ca":true},{"name":"Henry Millar","is_ca":true},{"name":"Rainer Malik","is_ca":true},{"name":"Christopher D. Anderson","is_ca":true},{"name":"Tushar Dave","is_ca":true},{"name":"Guido J. Falcone","is_ca":true},{"name":"Israel Fernández‐Cadenas","is_ca":true},{"name":"Jordi Jiménez-Conde","is_ca":true},{"name":"Joan Montaner","is_ca":true},{"name":"Martin O’Donnell","is_ca":true},{"name":"Guillaume Paré","is_ca":true},{"name":"Farid Radmanesh","is_ca":true},{"name":"Natalia S. Rost","is_ca":true},{"name":"Agnieszka Słowik","is_ca":true},{"name":"Martin Söderholm","is_ca":true},{"name":"Matthew Traylor","is_ca":true},{"name":"Sara L. Pulit","is_ca":true},{"name":"Sudha Seshadri","is_ca":true},{"name":"Brad Worrall","is_ca":true},{"name":"Daniel Woo","is_ca":true},{"name":"Hugh S. Markus","is_ca":true},{"name":"Braxton D. Mitchell","is_ca":true},{"name":"Martin Dichgans","is_ca":true},{"name":"Jonathan Rosand","is_ca":true},{"name":"Cathie Sudlow","is_ca":true},{"name":"Patrick F. McArdle","is_ca":false},{"name":"Quenna Wong","is_ca":false},{"name":"Katrina Gwinn","is_ca":false},{"name":"Sefanja Achterberg","is_ca":false},{"name":"Ale Algra","is_ca":false},{"name":"Philippe Amouyel","is_ca":true},{"name":"Donna K. Arnett","is_ca":false},{"name":"Ethem Murat Arsava","is_ca":false},{"name":"John Attia","is_ca":false},{"name":"Hakan Ay","is_ca":true},{"name":"Traci M. Bartz","is_ca":false},{"name":"Thomas W.K. Battey","is_ca":false},{"name":"Oscar Benavente","is_ca":false},{"name":"Steve Bevan","is_ca":true},{"name":"Alessandro Biffi","is_ca":false},{"name":"Joshua C. Bis","is_ca":false},{"name":"Susan H. Blanton","is_ca":false},{"name":"Philip St. John","is_ca":true},{"name":"Giorgio B. Boncoraglio","is_ca":false},{"name":"Robert D. Brown","is_ca":false},{"name":"A I Burgess","is_ca":false},{"name":"Caty Carrera","is_ca":false},{"name":"Sherita N. Chapman Smith","is_ca":false},{"name":"Daniel I. Chasman","is_ca":false},{"name":"Ganesh Chauhan","is_ca":true},{"name":"France Wei-Min Chen","is_ca":false},{"name":"Yu‐Ching Cheng","is_ca":false},{"name":"Lisa Cloonan","is_ca":false},{"name":"John W. Cole","is_ca":false},{"name":"Ioana Cotlarciuc","is_ca":true},{"name":"Carlos Cruchaga","is_ca":false},{"name":"Elisa Cuadrado‐Godia","is_ca":false},{"name":"Jesse Dawson","is_ca":false},{"name":"Stéphanie Debette","is_ca":true},{"name":"Hossein Delavaran","is_ca":false},{"name":"Cameron Dell","is_ca":false},{"name":"Kimberly F. Doheny","is_ca":false},{"name":"Chuanhui Dong","is_ca":false},{"name":"David Duggan","is_ca":false},{"name":"Gunnar Engström","is_ca":false},{"name":"Michele K. Evans","is_ca":false},{"name":"Xavier Estivill Pallejà","is_ca":false},{"name":"Jessica D. Faul","is_ca":false},{"name":"Myriam Fornage","is_ca":false},{"name":"Philippe M. Frossard","is_ca":false},{"name":"Karen L. Furie","is_ca":false},{"name":"Dale M. Gamble","is_ca":false},{"name":"Christian Gieger","is_ca":false},{"name":"Anne‐Katrin Giese","is_ca":false},{"name":"Eva Giralt‐Steinhauer","is_ca":false},{"name":"Hector M. González","is_ca":false},{"name":"An Goris","is_ca":false},{"name":"Sólveig Grétarsdóttir","is_ca":false},{"name":"Raji P. Grewal","is_ca":false},{"name":"Ulrike Grittner","is_ca":false},{"name":"Stefan Gustafsson","is_ca":false},{"name":"Buhm Han","is_ca":true},{"name":"Graeme J. Hankey","is_ca":false},{"name":"Laura Heitsch","is_ca":false},{"name":"Peter Higgins","is_ca":false},{"name":"Marc C. Hochberg","is_ca":false},{"name":"Elizabeth Holliday","is_ca":false},{"name":"Jemma C. Hopewell","is_ca":false},{"name":"Richard B. Horenstein","is_ca":false},{"name":"George Howard","is_ca":false},{"name":"M. Arfan Ikram","is_ca":false},{"name":"Andreea Ilinca","is_ca":false},{"name":"Erik Ingelsson","is_ca":false},{"name":"Marguerite R. Irvin","is_ca":false},{"name":"Rebecca D. Jackson","is_ca":false},{"name":"Christina Jern","is_ca":false},{"name":"Julie A. Johnson","is_ca":false},{"name":"Katarina Jood","is_ca":false},{"name":"Muhammed S. Kahn","is_ca":false},{"name":"Robert C. Kaplan","is_ca":false},{"name":"L. Jaap Kappelle","is_ca":false},{"name":"Sharon LR Kardia","is_ca":false},{"name":"Keith L. Keene","is_ca":false},{"name":"Brett Kissela","is_ca":false},{"name":"Dawn Kleindorfer","is_ca":false},{"name":"Simon A. Koblar","is_ca":false},{"name":"Daniel Labovitz","is_ca":true},{"name":"Lenore J. Launer","is_ca":false},{"name":"Cathy C. Laurie","is_ca":false},{"name":"Cecelia Laurie","is_ca":false},{"name":"Jin‐Moo Lee","is_ca":false},{"name":"Robin Lemmens","is_ca":true},{"name":"Christopher Levi","is_ca":true},{"name":"Didier Leys","is_ca":false},{"name":"W.T. Longstreth","is_ca":true},{"name":"Jane Maguire","is_ca":false},{"name":"Ani Manichaikul","is_ca":true},{"name":"Leslie A. McClure","is_ca":false},{"name":"Caitrin W. McDonough","is_ca":false},{"name":"Christa Meisinger","is_ca":false},{"name":"Olle Melander","is_ca":false},{"name":"James F. Meschia","is_ca":false},{"name":"Marina Mola-Caminal","is_ca":false},{"name":"Thomas H. Mosley","is_ca":false},{"name":"Martina Müller‐Nurasyid","is_ca":false},{"name":"Mike A. Nalls","is_ca":true},{"name":"Jeffrey R. O’Connell","is_ca":false},{"name":"Ángel Ois","is_ca":false},{"name":"George Papanicolaou","is_ca":false},{"name":"Leema Reddy Peddareddygari","is_ca":false},{"name":"Annie Pedersén","is_ca":false},{"name":"Joanna Pera","is_ca":true},{"name":"Annette Peters","is_ca":false},{"name":"Deborah Poole","is_ca":false},{"name":"Bruce M. Psaty","is_ca":false},{"name":"Raquel Rabionet","is_ca":false},{"name":"Miriam R. Raffeld","is_ca":false},{"name":"Asif Rasheed","is_ca":false},{"name":"Petra Redfors","is_ca":false},{"name":"Alex P. Reiner","is_ca":false},{"name":"Kathryn M. Rexrode","is_ca":false},{"name":"Marta Ribasés","is_ca":false},{"name":"Stephen S. Rich","is_ca":false},{"name":"Wim Robberecht","is_ca":false},{"name":"Ana Rodríguez-Campello","is_ca":false},{"name":"Arndt Rolfs","is_ca":false},{"name":"Jaume Roquer","is_ca":false},{"name":"Lynda M. Rose","is_ca":false},{"name":"Daniel M. Rosenbaum","is_ca":true},{"name":"Peter M. Rothwell","is_ca":false},{"name":"Tatjana Rundek","is_ca":false},{"name":"Kathleen A. Ryan","is_ca":false},{"name":"Ralph L. Sacco","is_ca":false},{"name":"Michèle M. Sale","is_ca":false},{"name":"Danish Saleheen","is_ca":true},{"name":"Veikko Salomaa","is_ca":false},{"name":"Cristina Sánchez‐Mora","is_ca":false},{"name":"Carsten Oliver Schmidt","is_ca":false},{"name":"Helena Schmidt","is_ca":false},{"name":"Reinhold Schmidt","is_ca":false},{"name":"Markus Schürks","is_ca":true},{"name":"Rodney J. Scott","is_ca":false},{"name":"Helen Segal","is_ca":false},{"name":"Stephan Seiler","is_ca":false},{"name":"Pankaj Sharma","is_ca":true},{"name":"Alan R. Shuldiner","is_ca":false},{"name":"Brian Silver","is_ca":false},{"name":"Jennifer A. Smith","is_ca":false},{"name":"Carolina Soriano Bsc","is_ca":false},{"name":"Mary J. Sparks","is_ca":false},{"name":"Tara M. Stanne","is_ca":false},{"name":"O. Colin Stine","is_ca":false},{"name":"Konstantin Strauch","is_ca":false},{"name":"Jonathan Sturm","is_ca":true},{"name":"Salman M. Tajuddin","is_ca":false},{"name":"Robert L. Talbert","is_ca":false},{"name":"Turgut Tatlisumak","is_ca":true},{"name":"Vincent Thijs","is_ca":true},{"name":"Guðmar Þorleifsson","is_ca":false},{"name":"Unnur Thorsteindottir","is_ca":false},{"name":"Stella Trompet","is_ca":false},{"name":"Valerie Valant","is_ca":false},{"name":"Mélanie Waldenberger","is_ca":false},{"name":"Matthew Walters","is_ca":true},{"name":"Liyong Wang","is_ca":false},{"name":"Xin-Qun Wang","is_ca":false},{"name":"Sylvia Wassertheil‐Smoller","is_ca":false},{"name":"David R. Weir","is_ca":false},{"name":"Kerri L. Wiggins","is_ca":false},{"name":"Stephen R. Williams","is_ca":false},{"name":"Dorota Włoch-Kopeć","is_ca":false},{"name":"Rebecca Woodfield","is_ca":false},{"name":"Ona Wu","is_ca":true},{"name":"Huichun Xu","is_ca":false},{"name":"Alan B. Zonderman","is_ca":false},{"name":"Paul I. W. de Bakker","is_ca":false},{"name":"Steven J. Kittner","is_ca":false},{"name":"JC Hopewell","is_ca":false},{"name":"E.G. Holliday","is_ca":false},{"name":"Wei Zhao","is_ca":true},{"name":"Patrícia Abrantes","is_ca":true},{"name":"J. Attia","is_ca":false},{"name":"TW Battey","is_ca":false},{"name":"Klaus Berger","is_ca":true},{"name":"GB Boncoraglio","is_ca":false},{"name":"YC Cheng","is_ca":false},{"name":"Chen Wm","is_ca":false},{"name":"Robert Clarke","is_ca":true},{"name":"José M. Ferro","is_ca":false},{"name":"DM Gamble","is_ca":true},{"name":"SJ Kittner","is_ca":false},{"name":"Peter Lichtner","is_ca":true},{"name":"Jianjun Liu","is_ca":true},{"name":"JF Meschia","is_ca":true},{"name":"SA Oliveira","is_ca":true},{"name":"AP Reiner","is_ca":false},{"name":"P M Rothwell","is_ca":false},{"name":"AM Vicente","is_ca":false},{"name":"Unnur Þorsteinsdóttir","is_ca":false},{"name":"Anita L. DeStefano","is_ca":false},{"name":"Peter Donnelly","is_ca":false},{"name":"Inês Barroso","is_ca":false},{"name":"Jenefer M. Blackwell","is_ca":false},{"name":"Elvira Bramon","is_ca":false},{"name":"Matthew A. Brown","is_ca":true},{"name":"Juan P. Casas","is_ca":false},{"name":"Aiden Corvin","is_ca":false},{"name":"Panos Deloukas","is_ca":false},{"name":"Audrey Duncanson","is_ca":false},{"name":"Janusz Jankowski","is_ca":false},{"name":"Christopher G. Mathew","is_ca":false},{"name":"Robert Plomin","is_ca":false},{"name":"Anna Rautanen","is_ca":false},{"name":"S. J. Sawcer","is_ca":false},{"name":"Richard C. Trembath","is_ca":false},{"name":"Ananth C. Viswanathan","is_ca":false},{"name":"Nicholas Wood","is_ca":false},{"name":"Chris C. A. Spencer","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03253750744653255,"gpt":0.3083116632505654,"spread":0.2757741558040329,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001836134,0.0007576293,0.0009666953,0.00106462,0.0005511942,0.000981465,0.0007497286,0.000854453,0.00312103],"category_scores_gemma":[0.003224864,0.0004091637,0.005675538,0.002035683,0.0004397446,0.0002770403,0.0006536084,0.0006028248,0.0001817932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003581914,"about_ca_system_score_gemma":0.000531874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01737679,"about_ca_topic_score_gemma":0.01713595,"domain_scores_codex":[0.9986538,0.000352698,0.0001444196,0.0005436329,0.0001553124,0.0001500544],"domain_scores_gemma":[0.9977654,0.0008676208,0.0006402793,0.0003499329,0.0001829045,0.000193782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003824087,0.00003339885,0.9411157,0.0005160526,0.04229273,0.0004891867,0.00008524558,0.0007524624,0.003765035,0.000125229,0.0009709532,0.006029803],"study_design_scores_gemma":[0.0002462436,0.0002654074,0.9602517,0.0001492286,0.0332239,0.0006976209,0.0001265918,0.002266126,0.00132879,0.0002779672,0.001143227,0.00002317079],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9761041,0.01648648,0.002400437,0.0005971534,0.0001832462,0.00004078167,0.002448448,0.0001090568,0.0016303],"genre_scores_gemma":[0.9974931,0.000727051,0.0005975718,0.000127851,0.00006804426,0.00001564921,0.0005890877,0.00001500458,0.0003667075],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01737679,"threshold_uncertainty_score":0.03455126,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2100678382","doi":"10.1161/01.str.0000080939.39414.83","title":"Development and Progression of Leukoaraiosis in Patients With Brain Ischemia and Carotid Artery Disease","year":2003,"lang":"en","type":"article","venue":"Stroke","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary; Sunnybrook Health Science Centre; Western University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Medicine; Leukoaraiosis; Stroke (engine); Cardiology; Carotid endarterectomy; Risk factor; Diabetes mellitus; Internal medicine; Ischemia; Vascular disease; Disease; Atheroma; Surgery; Carotid artery disease; Carotid arteries; Dementia; Endocrinology","authors":[{"name":"Jonathan Y. Streifler","is_ca":true},{"name":"Michael Eliasziw","is_ca":true},{"name":"Oscar Benavente","is_ca":true},{"name":"Sonia Alamowitch","is_ca":true},{"name":"Allan J. Fox","is_ca":true},{"name":"Vladimir Hachinski","is_ca":true},{"name":"Henry J.M. Barnett","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004712820654851338,"gpt":0.2168024475020676,"spread":0.2120896268472163,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006141813,0.0003333999,0.0004450084,0.0006613646,0.0004575117,0.0005689423,0.0002853057,0.0006394708,0.0007155747],"category_scores_gemma":[0.003065643,0.0002314283,0.0002878332,0.0007584925,0.0003316439,0.0005234705,0.0003786269,0.000645207,0.00012469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002570814,"about_ca_system_score_gemma":0.0002792421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002397289,"about_ca_topic_score_gemma":0.003418853,"domain_scores_codex":[0.9995479,0.0001351662,0.00005989156,0.00008106944,0.00008948983,0.00008640043],"domain_scores_gemma":[0.9977978,0.0002975875,0.001251218,0.0000679005,0.0001858054,0.0003996725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001629351,0.00002598742,0.9988921,0.000005605555,0.00001800532,0.0001028436,0.0000428133,0.00001795371,0.00007832515,0.000004194889,0.00002703661,0.0006222378],"study_design_scores_gemma":[0.000008296978,0.0001223115,0.999231,0.000004231169,0.00001448768,0.0004429455,0.00005300805,0.00005447967,0.00002110663,0.00001010575,0.00003612873,0.000001981328],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991123,0.0004611994,0.00002965166,0.00003752327,0.000004179938,0.000007038516,0.00007165511,0.000002047366,0.0002742989],"genre_scores_gemma":[0.9996091,0.000119006,0.00004404258,0.00002078764,0.00001424189,0.0000058874,0.0001388137,5.873915e-7,0.00004757912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002397289,"threshold_uncertainty_score":0.004766703,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2100628038","doi":"10.1186/1742-4933-6-13","title":"Pathophysiology of vascular dementia","year":2009,"lang":"en","type":"article","venue":"Immunity & Ageing","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Università degli Studi di Palermo","keywords":"Dementia; Medicine; Cognitive impairment; Vascular dementia; Etiology; Cognition; Stroke (engine); Intensive care medicine; Psychiatry; Pathology; Disease","authors":[{"name":"Francesco Iemolo","is_ca":true},{"name":"Giovanni Duro","is_ca":false},{"name":"Claudia Rizzo","is_ca":false},{"name":"Laura Castiglia","is_ca":false},{"name":"Vladimir Hachinski","is_ca":true},{"name":"Calogero Caruso","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008536773892126728,"gpt":0.2495849541818543,"spread":0.2410481802897275,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006091232,0.0005952627,0.0009292508,0.001409886,0.0007498908,0.002265207,0.001060812,0.001844232,0.002115949],"category_scores_gemma":[0.001030266,0.000221824,0.0004231266,0.0005155524,0.002255939,0.001522924,0.001544818,0.001853756,0.0007423596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008873317,"about_ca_system_score_gemma":0.001041074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008197899,"about_ca_topic_score_gemma":0.0004820654,"domain_scores_codex":[0.999639,0.0001154979,0.00002784986,0.00006397675,0.00007501178,0.00007864385],"domain_scores_gemma":[0.9995891,0.0001039959,0.0001051233,0.00002728729,0.00008730909,0.00008712834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00103874,0.0007503535,0.03527045,0.007150476,0.0005695873,0.02540615,0.009184034,0.002069406,0.04453377,0.3898674,0.04865002,0.4355096],"study_design_scores_gemma":[0.0002840541,0.001701852,0.06594561,0.004157514,0.0002937248,0.07665627,0.004898727,0.002510897,0.00744561,0.4695915,0.3663167,0.0001975041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.106833,0.7960742,0.0138862,0.03038193,0.003955049,0.0001918457,0.0003505353,0.0002904657,0.04803673],"genre_scores_gemma":[0.6272596,0.3473741,0.005854462,0.005363997,0.004573086,0.0002650761,0.0002651999,0.00001957656,0.009024967],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002265207,"threshold_uncertainty_score":0.007078528,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2115062467","doi":"10.1152/ajpcell.00415.2006","title":"Notch signaling in the developing cardiovascular system","year":2007,"lang":"en","type":"review","venue":"American Journal of Physiology-Cell Physiology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"","keywords":"CADASIL; Notch signaling pathway; Leukoencephalopathy; Notch proteins; Biology; Hes3 signaling axis; Alagille syndrome; Neuroscience; Signal transduction; Pathology; Anatomy; Cell biology; Medicine; Endocrinology","authors":[{"name":"Kyle Niessen","is_ca":true},{"name":"Aly Karsan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03019097902234389,"gpt":0.3068091835308869,"spread":0.276618204508543,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003287491,0.0005318989,0.0007060112,0.001368253,0.0002839586,0.0007120106,0.0005970812,0.0008489395,0.002133283],"category_scores_gemma":[0.0002484342,0.0001728225,0.0001743768,0.001235079,0.0003997969,0.0009832034,0.0005053809,0.0009656519,0.002168371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005191618,"about_ca_system_score_gemma":0.0007418112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000933316,"about_ca_topic_score_gemma":0.001196014,"domain_scores_codex":[0.9999096,0.0000154032,0.00001340125,0.00001629091,0.00003702453,0.000008296939],"domain_scores_gemma":[0.999916,0.00002677822,0.00001072417,0.000003178065,0.00002867381,0.00001466461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005138878,0.00004483894,0.0002703111,0.003175945,0.00003298846,0.0006626045,0.00008383874,0.0005071425,0.003618155,0.005550156,0.01873026,0.9672724],"study_design_scores_gemma":[0.00001107988,0.00006565819,0.001230857,0.001445558,0.00004527118,0.003536589,0.00009668975,0.0001514192,0.001059806,0.003935392,0.9884064,0.00001520861],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004206629,0.9962838,0.0003463311,0.000269943,0.0001653662,0.000004453682,0.00001125978,0.00001180176,0.002486525],"genre_scores_gemma":[0.001623703,0.9964276,0.0003219717,0.0001289291,0.000189657,0.000004632216,0.00001820891,0.000001175944,0.001284144],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002133283,"threshold_uncertainty_score":0.007136524,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2989789399","doi":"10.1177/0271678x19888967","title":"Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative","year":2019,"lang":"en","type":"review","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Medical Research Council; ZonMw; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Atrophy; Context (archaeology); Neuroscience; Cognition; Medicine; Cerebral atrophy; Brain damage; Pathology; Psychology; Biology","authors":[{"name":"François De Guio","is_ca":false},{"name":"Marco Duering","is_ca":false},{"name":"Franz Fazekas","is_ca":false},{"name":"Frank‐Erik de Leeuw","is_ca":false},{"name":"Steven M. Greenberg","is_ca":false},{"name":"Leonardo Pantoni","is_ca":false},{"name":"Agnès Aghetti","is_ca":false},{"name":"Eric E. Smith","is_ca":true},{"name":"Joanna M. Wardlaw","is_ca":false},{"name":"Éric Jouvent","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06681587670754004,"gpt":0.3061942406052112,"spread":0.2393783638976712,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001659596,0.0007789573,0.001731225,0.003592508,0.0002621046,0.001496979,0.0009072112,0.001302728,0.002809894],"category_scores_gemma":[0.002944564,0.0003102279,0.001006419,0.002980362,0.0006154819,0.001735163,0.0007549749,0.001476075,0.000932051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006628715,"about_ca_system_score_gemma":0.002111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001345493,"about_ca_topic_score_gemma":0.002623799,"domain_scores_codex":[0.999563,0.00009429176,0.0001236021,0.00007397623,0.0001159064,0.00002922287],"domain_scores_gemma":[0.9977386,0.001536085,0.0002432074,0.00004090717,0.0003844895,0.00005658751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001001025,0.00003095505,0.0003951759,0.05312753,0.0002874799,0.0001736992,0.00009030957,0.0002041758,0.0006489964,0.002806311,0.02145221,0.9206831],"study_design_scores_gemma":[0.00003910591,0.000210976,0.004017382,0.04736659,0.001242206,0.003974482,0.0002221929,0.0001892649,0.0006222394,0.004645517,0.9374155,0.00005464079],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005167434,0.9993089,0.00004366689,0.0002476069,0.0001196932,0.000001833495,0.0000109954,0.000002319351,0.0002132942],"genre_scores_gemma":[0.0004277138,0.9989587,0.0001185283,0.0001738913,0.0001767583,0.000004061903,0.00001818491,0.000001186386,0.0001210057],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003592508,"threshold_uncertainty_score":0.00940001,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1912032010","doi":"10.1111/bpa.12041","title":"Quantitative Vascular Pathology and Phenotyping Familial and Sporadic Cerebral Small Vessel Diseases","year":2013,"lang":"en","type":"article","venue":"Brain Pathology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Alzheimer Society","keywords":"Pathology; Medicine","authors":[{"name":"Lucinda Craggs","is_ca":false},{"name":"Christian Hagel","is_ca":false},{"name":"Gregor Kuhlenbäeumer","is_ca":false},{"name":"Anne Börjesson‐Hanson","is_ca":false},{"name":"Oluf Andersen","is_ca":false},{"name":"Matti Viitanen","is_ca":false},{"name":"Hannu Kalimo","is_ca":false},{"name":"Catriona McLean","is_ca":false},{"name":"Janet Y. Slade","is_ca":false},{"name":"Roslyn Hall","is_ca":false},{"name":"Arthur E. Oakley","is_ca":false},{"name":"Yumi Yamamoto","is_ca":false},{"name":"Vincent Deramecourt","is_ca":false},{"name":"Raj N. Kalaria","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01246903990732489,"gpt":0.2411876393185132,"spread":0.2287185994111883,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004384968,0.0003344829,0.0001707576,0.001919809,0.0001697233,0.000282871,0.0001062804,0.0002362329,0.0007991551],"category_scores_gemma":[0.0007871545,0.0001663251,0.0001207822,0.0006242114,0.0002962315,0.0001143248,0.0001749659,0.0001319668,0.00008344708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002004369,"about_ca_system_score_gemma":0.00009670408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002127382,"about_ca_topic_score_gemma":0.003633813,"domain_scores_codex":[0.9997444,0.00006002061,0.00002366977,0.00007315323,0.00006143933,0.00003730324],"domain_scores_gemma":[0.99949,0.0001085317,0.0001806314,0.00005899842,0.00008908368,0.00007272907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001010763,0.0001010539,0.7088911,0.0001343004,0.0003486938,0.003136445,0.0009831736,0.001023353,0.260236,0.0003075439,0.0001766274,0.02365096],"study_design_scores_gemma":[0.000008893968,0.0002498643,0.9826179,0.000009003176,0.00005801089,0.004966823,0.0001579071,0.0008141263,0.01070257,0.0001534819,0.0002528793,0.000008484094],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989167,0.0001445372,0.0006068079,0.000002385966,9.7082e-7,0.000004060392,0.00007965561,0.00001447248,0.0002304173],"genre_scores_gemma":[0.9988946,0.00005759377,0.0007995946,0.00000317957,0.000001642118,0.000003416067,0.000118957,0.000003760463,0.0001171878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002127382,"threshold_uncertainty_score":0.004230022,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4407689796","doi":"10.1152/physrev.00028.2024","title":"The pathogenesis of cerebral small vessel disease and vascular cognitive impairment","year":2025,"lang":"en","type":"review","venue":"Physiological Reviews","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ste. Anne's Hospital","funders":"British Heart Foundation Centre of Regenerative Medicine; National Institute of Neurological Disorders and Stroke; National Institutes of Health; Fondation pour la Recherche Médicale; Fondation Leducq; Agence Nationale de la Recherche; British Heart Foundation; National Institute for Health and Care Research","keywords":"Hyperintensity; Neuroscience; Neuroimaging; Disease; Cognition; Medicine; Cognitive impairment; Pathology; Psychology; Magnetic resonance imaging; Radiology","authors":[{"name":"Hugh S. Markus","is_ca":false},{"name":"Anne Joutel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05688293456718264,"gpt":0.3378828478512355,"spread":0.2809999132840528,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008748073,0.0009255551,0.0008999556,0.001408689,0.0004447641,0.001522628,0.0006673396,0.00161876,0.002167281],"category_scores_gemma":[0.001089379,0.0001833636,0.0004177291,0.0009434835,0.001343686,0.001272198,0.0008976694,0.002186215,0.001077195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008165143,"about_ca_system_score_gemma":0.001498601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001733294,"about_ca_topic_score_gemma":0.00140211,"domain_scores_codex":[0.9996756,0.0001003695,0.00003999306,0.00006256693,0.00007916867,0.00004229478],"domain_scores_gemma":[0.9996576,0.00014658,0.0000576774,0.00001371753,0.00008666632,0.00003776845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002016981,0.00009644908,0.00153269,0.01122693,0.000194646,0.00115627,0.0005915388,0.0004434291,0.006027082,0.04393322,0.07397064,0.8606254],"study_design_scores_gemma":[0.00002734471,0.0002253051,0.006978992,0.005122341,0.0001502673,0.005430833,0.0004042545,0.0001995409,0.001698502,0.02994439,0.94976,0.00005823332],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004694749,0.994087,0.0004570369,0.002782268,0.0008777936,0.00000597311,0.00002180996,0.0000178818,0.001280834],"genre_scores_gemma":[0.003780105,0.9931383,0.0004013703,0.0007275914,0.001158217,0.00001088184,0.00003216787,0.000003586855,0.0007478402],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002167281,"threshold_uncertainty_score":0.007250309,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2130461216","doi":"10.1161/strokeaha.113.001857","title":"Stroke Genetics Network (SiGN) Study","year":2013,"lang":"en","type":"review","venue":"Stroke","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Bentley (Canada)","funders":"National Center for Research Resources; Instituto de Salud Carlos III; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; National Center for Advancing Translational Sciences; National Human Genome Research Institute; Wellcome Trust; National Institute of Neurological Disorders and Stroke; Massachusetts General Hospital; National Institute for Health and Care Research; National Institute on Aging; University of Washington","keywords":"Medicine; Stroke (engine); Genome-wide association study; Genotype; CADASIL; Genotyping; Bioinformatics; Single-nucleotide polymorphism; Genetics; Pathology; Gene; Biology; Leukoencephalopathy; Disease","authors":[{"name":"James F. Meschia","is_ca":false},{"name":"Donna K. Arnett","is_ca":false},{"name":"Hakan Ay","is_ca":false},{"name":"Robert D. Brown","is_ca":false},{"name":"Oscar Benavente","is_ca":false},{"name":"John W. Cole","is_ca":false},{"name":"Paul I. W. de Bakker","is_ca":false},{"name":"Martin Dichgans","is_ca":false},{"name":"Kimberly F. Doheny","is_ca":false},{"name":"Myriam Fornage","is_ca":false},{"name":"Raji P. Grewal","is_ca":false},{"name":"Katrina Gwinn","is_ca":false},{"name":"Christina Jern","is_ca":false},{"name":"Jordi Jiménez Conde","is_ca":false},{"name":"Julie A. Johnson","is_ca":false},{"name":"Katarina Jood","is_ca":false},{"name":"Cathy C. Laurie","is_ca":false},{"name":"Jin‐Moo Lee","is_ca":false},{"name":"Hugh S. Markus","is_ca":false},{"name":"Patrick F. McArdle","is_ca":false},{"name":"Leslie A. McClure","is_ca":false},{"name":"Braxton D. Mitchell","is_ca":false},{"name":"Reinhold Schmidt","is_ca":false},{"name":"Kathryn M. Rexrode","is_ca":false},{"name":"Stephen S. Rich","is_ca":false},{"name":"Jonathan Rosand","is_ca":false},{"name":"Peter M. Rothwell","is_ca":false},{"name":"Tatjana Rundek","is_ca":false},{"name":"Ralph L. Sacco","is_ca":false},{"name":"Pankaj Sharma","is_ca":false},{"name":"Alan R. Shuldiner","is_ca":false},{"name":"Agnieszka Słowik","is_ca":false},{"name":"Sylvia Wassertheil‐Smoller","is_ca":false},{"name":"Cathie Sudlow","is_ca":false},{"name":"Vincent Thijs","is_ca":false},{"name":"Daniel Woo","is_ca":false},{"name":"Bradford B. Worrall","is_ca":false},{"name":"Ona Wu","is_ca":false},{"name":"Steven J. Kittner","is_ca":false},{"name":"Christopher D. Anderson","is_ca":false},{"name":"Kerstin Andrén","is_ca":false},{"name":"Gunnar Andsberg","is_ca":false},{"name":"Ethem Murat Arsava","is_ca":false},{"name":"Kevin M. Barrett","is_ca":false},{"name":"Thomas Benner","is_ca":true},{"name":"Paul Bentley","is_ca":false},{"name":"Alessandro Biffi","is_ca":false},{"name":"David A. Brenner","is_ca":false},{"name":"Sherita Chapman","is_ca":false},{"name":"Yu‐Ching Cheng","is_ca":false},{"name":"Hossein Delavaran","is_ca":false},{"name":"Chris Deline","is_ca":false},{"name":"Tomasz Dziedzic","is_ca":false},{"name":"Dale M. Gamble","is_ca":false},{"name":"Eva Giralt","is_ca":false},{"name":"Anja Grazer","is_ca":false},{"name":"Andreas Gschwendtner","is_ca":false},{"name":"Caityln Hegge","is_ca":false},{"name":"Laura Heitsch","is_ca":false},{"name":"Johanna Helenius","is_ca":false},{"name":"Lukas Holmegaard","is_ca":false},{"name":"Mohammed Saiful Huq","is_ca":false},{"name":"Robert E. Irie","is_ca":false},{"name":"Rebecca D. Jackson","is_ca":false},{"name":"Petra Katschnig","is_ca":false},{"name":"Michael Katsnelson","is_ca":false},{"name":"Naïm Khoury","is_ca":false},{"name":"Selma Kilinc","is_ca":false},{"name":"Daniel Labovitz","is_ca":false},{"name":"Silvia Lanfranconi","is_ca":false},{"name":"Carl D. Langefeld","is_ca":false},{"name":"Robin Lemmens","is_ca":false},{"name":"Linxin Li","is_ca":false},{"name":"Shaneela Malik","is_ca":false},{"name":"Olle Melander","is_ca":false},{"name":"Sara Nordström","is_ca":false},{"name":"Bo Norrving","is_ca":false},{"name":"Ángel Ois","is_ca":false},{"name":"Raid G. Ossi","is_ca":false},{"name":"Leema Reddy Peddareddygari","is_ca":false},{"name":"Annie Pedersén","is_ca":false},{"name":"Joanna Pera","is_ca":false},{"name":"Mateusz Pucek","is_ca":false},{"name":"Kristiina Rannikmäe","is_ca":false},{"name":"Petra Redfors","is_ca":false},{"name":"J. Rhodes","is_ca":false},{"name":"Marta Ribasés","is_ca":false},{"name":"Neha Saraf","is_ca":false},{"name":"Markus Schuerks","is_ca":false},{"name":"Stephan Seiler","is_ca":false},{"name":"Huma U. Sheikh","is_ca":false},{"name":"Andrew M. Southerland","is_ca":false},{"name":"Mary J. Sparks","is_ca":false},{"name":"Eva Stoegerer","is_ca":false},{"name":"Jordi Sunyer","is_ca":false},{"name":"Ella Temple","is_ca":false},{"name":"Raffaella Valenti","is_ca":false},{"name":"David R. Weir","is_ca":false},{"name":"Darren Weissman","is_ca":false},{"name":"Rebecca Woodfield","is_ca":false},{"name":"Gabriel Yiin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04022009232736035,"gpt":0.3306494756098377,"spread":0.2904293832824774,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002486274,0.0009841514,0.002806969,0.002147916,0.0002728714,0.0006571762,0.0009346802,0.0009903314,0.005357024],"category_scores_gemma":[0.004989703,0.0001898522,0.00173969,0.00357353,0.0002022925,0.0005356878,0.0005733687,0.000940115,0.000733083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000887273,"about_ca_system_score_gemma":0.002538132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003843497,"about_ca_topic_score_gemma":0.005977629,"domain_scores_codex":[0.9989867,0.0004402639,0.0001406312,0.0001530305,0.0002229815,0.00005642826],"domain_scores_gemma":[0.9986326,0.0008567842,0.0002164475,0.00004681541,0.0001848454,0.00006243051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001699689,0.0000800522,0.007052012,0.08406734,0.01661336,0.000393433,0.00006426623,0.0006683333,0.0002028927,0.002789746,0.07913714,0.8072318],"study_design_scores_gemma":[0.003127056,0.0006968824,0.06837074,0.102985,0.07087146,0.004387572,0.000145547,0.000792658,0.0007613036,0.007892939,0.7398422,0.0001265888],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005398067,0.9964703,0.0001376169,0.0006267609,0.0001923133,0.00004841088,0.0004554793,0.00001164751,0.00151763],"genre_scores_gemma":[0.01009024,0.98695,0.0004606235,0.0005855177,0.0003245634,0.0001720573,0.0008345413,0.000005260964,0.0005773238],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005357024,"threshold_uncertainty_score":0.01792103,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2922106038","doi":"10.1093/brain/awz024","title":"Association of variants in<i>HTRA1</i>and<i>NOTCH3</i>with MRI-defined extremes of cerebral small vessel disease in older subjects","year":2019,"lang":"en","type":"article","venue":"Brain","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill Genome Centre","funders":"H2020 European Research Council; Fondation Leducq; Agence Nationale de la Recherche; National Center for Research Resources; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; Medical Research Council; Canadian Institutes of Health Research; National Institute on Aging; Diabetes Research Center; National Institutes of Health; National Health and Medical Research Council; National Institute of Diabetes and Digestive and Kidney Diseases; Fondation Claude Pompidou; Université de Bordeaux; Bundesministerium für Wissenschaft, Forschung und Wirtschaft; National Institute of Neurological Disorders and Stroke; Center for Hellenic Studies, Harvard University; Bundesministerium für Bildung und Forschung; ZonMw; National Human Genome Research Institute; European Commission; EU Joint Programme – Neurodegenerative Disease Research; Indiana Clinical and Translational Sciences Institute","keywords":"Exome; Exome sequencing; Genetics; Population; Genetic association; Linkage disequilibrium; Genome-wide association study; Candidate gene; Disease; Hyperintensity; Phenotype; Biology; Medicine; Genotype; Pathology; Gene; Magnetic resonance imaging; Single-nucleotide polymorphism","authors":[{"name":"Aniket Mishra","is_ca":false},{"name":"Ganesh Chauhan","is_ca":false},{"name":"Marie‐Hélène Violleau","is_ca":false},{"name":"Dina Vojinović","is_ca":false},{"name":"Xueqiu Jian","is_ca":false},{"name":"Shuo Li","is_ca":false},{"name":"Yasaman Saba","is_ca":false},{"name":"Benjamin Grenier‐Boley","is_ca":false},{"name":"Qiong Yang","is_ca":false},{"name":"Traci M. Bartz","is_ca":false},{"name":"Edith Hofer","is_ca":false},{"name":"Aïcha Soumaré","is_ca":false},{"name":"Fen Peng","is_ca":false},{"name":"Marie-Gabrielle Duperron","is_ca":false},{"name":"Mario Foglio","is_ca":true},{"name":"Thomas H. Mosley","is_ca":false},{"name":"Reinhold Schmidt","is_ca":false},{"name":"Bruce M. Psaty","is_ca":false},{"name":"Lenore J. Launer","is_ca":false},{"name":"Eric Boerwinkle","is_ca":false},{"name":"Yi‐Cheng Zhu","is_ca":false},{"name":"Bernard Mazoyer","is_ca":false},{"name":"Mark Lathrop","is_ca":true},{"name":"Céline Bellenguez","is_ca":false},{"name":"Cornelia M. van Duijn","is_ca":false},{"name":"M. Arfan Ikram","is_ca":false},{"name":"Helena Schmidt","is_ca":false},{"name":"W.T. Longstreth","is_ca":false},{"name":"Myriam Fornage","is_ca":false},{"name":"Sudha Seshadri","is_ca":false},{"name":"Anne Joutel","is_ca":false},{"name":"Christophe Tzourio","is_ca":false},{"name":"Stéphanie Debette","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005751130671896696,"gpt":0.2074178624895233,"spread":0.2016667318176266,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007179555,0.0004632703,0.0003945506,0.0009285587,0.0003745006,0.0004384339,0.0003527474,0.0005123006,0.00140499],"category_scores_gemma":[0.001768369,0.0001746709,0.0005874436,0.0006076003,0.0003488518,0.0001647454,0.0006211115,0.0003647458,0.0001418526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001011287,"about_ca_system_score_gemma":0.0001489313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002192443,"about_ca_topic_score_gemma":0.003068636,"domain_scores_codex":[0.9994374,0.0001427142,0.00007532378,0.000247133,0.00005771052,0.00003980441],"domain_scores_gemma":[0.9989737,0.0002917593,0.0003761371,0.000187053,0.00005513206,0.0001160971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002072297,0.00006554263,0.9632271,0.00003179907,0.000354804,0.001071093,0.0002709817,0.0004027717,0.02675795,0.0001696097,0.0001110328,0.005465086],"study_design_scores_gemma":[0.0000484472,0.0002978705,0.9950863,0.000004565123,0.0001344379,0.001740524,0.00006113383,0.0004860546,0.001665815,0.000201146,0.0002603033,0.00001343421],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99875,0.0000422354,0.0006552826,0.00001142563,0.000002136726,0.000007234684,0.0003640799,0.000007698366,0.0001599349],"genre_scores_gemma":[0.9982885,0.00002895426,0.0009211941,0.00002790943,0.000007775814,0.00001788488,0.0005632403,0.000008385166,0.000136172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002192443,"threshold_uncertainty_score":0.004700184,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2084292448","doi":"10.4997/jrcpe.2011.121","title":"Vascular cognitive impairment: epidemiology, subtypes, diagnosis and management","year":2011,"lang":"en","type":"review","venue":"The Journal of the Royal College of Physicians of Edinburgh","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; Heart and Stroke Foundation; University of Toronto; Sunnybrook Health Science Centre","funders":"H. Lundbeck A/S; Eisai; Heart and Stroke Foundation of Canada; University of Toronto; GlaxoSmithKline; Pfizer; Canadian Institutes of Health Research; Sunnybrook Research Institute; Bristol-Myers Squibb","keywords":"Dementia; Stroke (engine); Vascular dementia; Medicine; Hyperintensity; Covert; Cognition; Epidemiology; Delirium; Cognitive decline; Vascular disease; Disease; Cardiology; Magnetic resonance imaging; Physical medicine and rehabilitation; Intensive care medicine; Physical therapy; Internal medicine; Psychiatry; Radiology","authors":[{"name":"Sandra E. Black","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03361263661248459,"gpt":0.3025762788250346,"spread":0.26896364221255,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009543243,0.001056378,0.002545235,0.003597375,0.0002822662,0.001029907,0.00136883,0.001191672,0.002212402],"category_scores_gemma":[0.002196859,0.0003558736,0.0006234058,0.003951684,0.0006464103,0.00125578,0.0006067536,0.001585683,0.001109822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001104992,"about_ca_system_score_gemma":0.001575686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004668195,"about_ca_topic_score_gemma":0.006569024,"domain_scores_codex":[0.9996007,0.0000788417,0.00009648646,0.00005735604,0.0001337023,0.00003283344],"domain_scores_gemma":[0.9993039,0.0002968074,0.000147285,0.00001356914,0.0001836135,0.00005484602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00008582507,0.00006691819,0.000529053,0.02247017,0.000147952,0.0002061636,0.00005821649,0.0002954938,0.0001706987,0.0007231763,0.0395182,0.9357283],"study_design_scores_gemma":[0.0001072243,0.0002379044,0.01114223,0.04404859,0.00079051,0.006852525,0.0003618732,0.0003276762,0.00026111,0.003419062,0.9323813,0.00006991782],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006981843,0.9993842,0.00003130661,0.0001854635,0.00009690972,0.000003164513,0.00001115105,0.000003025705,0.0002148819],"genre_scores_gemma":[0.0004929593,0.999081,0.00007083463,0.00008186893,0.0001339889,0.000003962914,0.00002417167,6.205167e-7,0.0001105507],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004668195,"threshold_uncertainty_score":0.009282053,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2981453649","doi":"10.1172/jci.insight.131344","title":"ER stress and Rho kinase activation underlie the vasculopathy of CADASIL","year":2019,"lang":"en","type":"article","venue":"JCI Insight","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Neurosciences Foundation; Stroke Association; British Heart Foundation; Canadian Institutes of Health Research; Medical Research Council; University of Ottawa","keywords":"CADASIL; Leukoencephalopathy; Unfolded protein response; Vascular smooth muscle; Medicine; Internal medicine; Endoplasmic reticulum; Endocrinology; Biology; Cell biology; Disease","authors":[{"name":"Karla B Neves","is_ca":false},{"name":"Adam Harvey","is_ca":false},{"name":"Fiona Moreton","is_ca":false},{"name":"Augusto C. Montezano","is_ca":false},{"name":"Francisco J. Rios","is_ca":false},{"name":"Rhéure Alves-Lopes","is_ca":false},{"name":"Aurélie Nguyen Dinh Cat","is_ca":false},{"name":"Paul Rocchicciolli","is_ca":false},{"name":"Christian Delles","is_ca":false},{"name":"Anne Joutel","is_ca":false},{"name":"Keith W. Muir","is_ca":false},{"name":"Rhian M. Touyz","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008536266261337798,"gpt":0.2262616462024435,"spread":0.2177253799411057,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001216026,0.0004771943,0.0002211993,0.0003672451,0.0001994865,0.0002636819,0.0001775663,0.0003630373,0.0009000667],"category_scores_gemma":[0.00009006722,0.000151769,0.000256952,0.0001460988,0.0002997486,0.0001647987,0.0002139946,0.0004299841,0.0001912228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002479373,"about_ca_system_score_gemma":0.0001341274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004585305,"about_ca_topic_score_gemma":0.0009465128,"domain_scores_codex":[0.9999171,0.00001390581,0.000008385258,0.00002172812,0.00001718384,0.00002169963],"domain_scores_gemma":[0.9999367,0.000006889068,0.00002560161,0.000008409785,0.000007328844,0.00001504652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009387578,0.00007309917,0.01355221,0.0001222732,0.00005850075,0.003900712,0.0001170721,0.00015825,0.9731849,0.0005098754,0.00017399,0.007210296],"study_design_scores_gemma":[0.0001564264,0.00130855,0.4746177,0.00008899189,0.0003836531,0.02374846,0.0004747871,0.002694976,0.4892541,0.002043815,0.005200077,0.00002834317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954641,0.002099019,0.00109498,0.0001165203,0.00001134448,0.00001037842,0.0001175259,0.00004272493,0.001043339],"genre_scores_gemma":[0.9978325,0.001057117,0.0003795058,0.00005516006,0.00001373554,0.00000573539,0.0001984856,0.000003594034,0.0004542839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009000667,"threshold_uncertainty_score":0.003010988,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2786759697","doi":"10.1016/j.neurobiolaging.2018.01.015","title":"Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3","year":2018,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute on Aging; Medical Research Council; Rheinische Friedrich-Wilhelms-Universität Bonn; University of Bristol; Queen's University Belfast; University College London; University of Southampton; University of Oxford; Parkinson's UK; University of Leeds; National Institute for Health and Care Research; Alzheimer's Society; Wellcome Trust; University of Dundee; National Institutes of Health; Queen's University; U.S. Department of Health and Human Services","keywords":"Leukodystrophy; Leukoencephalopathy; Metachromatic leukodystrophy; Dementia; Pathology; White matter; Biology; Medicine; Disease; Genetics; Magnetic resonance imaging","authors":[{"name":"Celeste Sassi","is_ca":false},{"name":"Michael A. Nalls","is_ca":false},{"name":"Perry G. Ridge","is_ca":false},{"name":"J. Raphael Gibbs","is_ca":false},{"name":"Michelle K. Lupton","is_ca":false},{"name":"Claire Troakes","is_ca":false},{"name":"Katie Lunnon","is_ca":false},{"name":"Safa Al‐Sarraj","is_ca":false},{"name":"Kristelle Brown","is_ca":false},{"name":"Christopher Medway","is_ca":false},{"name":"Jenny Lord","is_ca":false},{"name":"James Turton","is_ca":false},{"name":"José Brás","is_ca":false},{"name":"Sonja Blumenau","is_ca":false},{"name":"Mareike Thielke","is_ca":false},{"name":"Christa Josties","is_ca":false},{"name":"Dorette Freyer","is_ca":false},{"name":"A. Dietrich","is_ca":false},{"name":"Monia Hammer","is_ca":false},{"name":"Michael Baier","is_ca":false},{"name":"Ulrich Dirnagl","is_ca":false},{"name":"Kevin Morgan","is_ca":false},{"name":"John Powell","is_ca":false},{"name":"John S.K. Kauwe","is_ca":false},{"name":"Carlos Cruchaga","is_ca":false},{"name":"Alison Goate","is_ca":false},{"name":"Andrew B. Singleton","is_ca":false},{"name":"Rita Guerreiro","is_ca":false},{"name":"Angela Hodges","is_ca":false},{"name":"John Hardy","is_ca":false},{"name":"Peter Passmore","is_ca":false},{"name":"David Craig","is_ca":false},{"name":"Janet M. Johnston","is_ca":false},{"name":"Bernadette McGuinness","is_ca":false},{"name":"Stephen Todd","is_ca":false},{"name":"Reinhard Heun","is_ca":false},{"name":"Heike Kölsch","is_ca":false},{"name":"Patrick G. Kehoe","is_ca":false},{"name":"Emma Vardy","is_ca":false},{"name":"Nigel M. Hooper","is_ca":false},{"name":"David Mann","is_ca":false},{"name":"Stuart Pickering‐Brown","is_ca":false},{"name":"James Lowe","is_ca":false},{"name":"A. David Smith","is_ca":false},{"name":"Gordon Wilcock","is_ca":false},{"name":"Donald Warden","is_ca":false},{"name":"Clive Holmes","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.010951963868703,"gpt":0.2821933162677545,"spread":0.2712413523990514,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270176,0.000339707,0.0001798796,0.000491039,0.0001425178,0.0001772114,0.0001919844,0.0001793762,0.001001865],"category_scores_gemma":[0.0001271839,0.0001113293,0.0001619871,0.0002457912,0.0001991149,0.00009403123,0.0001751505,0.0002220229,0.0001385813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001898997,"about_ca_system_score_gemma":0.0001589299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001166373,"about_ca_topic_score_gemma":0.002211544,"domain_scores_codex":[0.9998697,0.00001807768,0.00001453966,0.00003460086,0.00004307494,0.00002003624],"domain_scores_gemma":[0.9999081,0.00002026492,0.00003141783,0.00001064834,0.000008317492,0.00002116933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002295062,0.00001424167,0.001703105,0.00002777407,0.00001031859,0.0006481612,0.00002349923,0.00007375843,0.9949203,0.0001570003,0.00004284186,0.002149469],"study_design_scores_gemma":[0.0001199446,0.0005616532,0.2428386,0.00003860379,0.0002068182,0.01296837,0.0002180341,0.002235879,0.7311126,0.0005672358,0.009088063,0.00004426005],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950949,0.001407775,0.001792608,0.00004800834,0.00001100536,0.00001521924,0.0007182442,0.00004461179,0.000867589],"genre_scores_gemma":[0.9953899,0.001060463,0.001741435,0.00005511568,0.000006763371,0.00002659327,0.0005564353,0.00002726127,0.001136107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001166373,"threshold_uncertainty_score":0.003351569,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3201852253","doi":"10.3389/fnagi.2021.711784","title":"Increased Levels of Circulating Angiogenic Cells and Signaling Proteins in Older Adults With Cerebral Small Vessel Disease","year":2021,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Alzheimer's Association; National Science Foundation","keywords":"Medicine; Angiogenesis; Dementia; Progenitor cell; Internal medicine; Hyperintensity; CD34; Stroke (engine); Vascular endothelial growth factor; Vascular dementia; Magnetic resonance imaging; Disease; Oncology; Cardiology; Stem cell; VEGF receptors; Biology","authors":[{"name":"Arunima Kapoor","is_ca":false},{"name":"Aimée Gaubert","is_ca":false},{"name":"Anisa Marshall","is_ca":false},{"name":"Irene B. Meier","is_ca":false},{"name":"Belinda Yew","is_ca":false},{"name":"Jean K. Ho","is_ca":false},{"name":"Anna E. Blanken","is_ca":false},{"name":"Shubir Dutt","is_ca":false},{"name":"Isabel J. Sible","is_ca":false},{"name":"Yanrong Li","is_ca":false},{"name":"Jung Yun Jang","is_ca":false},{"name":"Adam M. Brickman","is_ca":false},{"name":"Kathleen E. Rodgers","is_ca":false},{"name":"Daniel A. Nation","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01075806250089898,"gpt":0.2165978780726902,"spread":0.2058398155717912,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003385152,0.0002581225,0.0003390077,0.0005073125,0.0002076396,0.0003329368,0.0001004908,0.0002575584,0.001342203],"category_scores_gemma":[0.001247564,0.000122634,0.0001983439,0.0005558446,0.0001110079,0.0002207629,0.0001886835,0.0003287356,0.0001706063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001030938,"about_ca_system_score_gemma":0.00009942389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00115838,"about_ca_topic_score_gemma":0.001265671,"domain_scores_codex":[0.9998744,0.00002594979,0.00001890978,0.00003016919,0.00003129265,0.00001916506],"domain_scores_gemma":[0.9993582,0.0001232153,0.0002947055,0.00002533041,0.0001003063,0.00009815252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002940962,0.00002693249,0.9960613,0.00001822989,0.00005372404,0.0001006665,0.00007197363,0.00003250421,0.0006896944,0.0000091774,0.00006310907,0.002578692],"study_design_scores_gemma":[0.000006340058,0.0001360908,0.9990988,0.000006477793,0.00004810232,0.0002924592,0.00006310504,0.0001188251,0.00009244012,0.00002107548,0.0001145781,0.000001748818],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991519,0.0003884181,0.00008139804,0.00001755871,0.000003978995,0.00000276942,0.0001285469,0.000002558843,0.0002228407],"genre_scores_gemma":[0.9994459,0.0001500643,0.0001137586,0.00001762203,0.00001191102,0.000005135815,0.0001464486,7.208993e-7,0.0001084717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001342203,"threshold_uncertainty_score":0.004490137,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2805001872","doi":"10.1002/acn3.574","title":"Altered dynamics of neurovascular coupling in CADASIL","year":2018,"lang":"en","type":"article","venue":"Annals of Clinical and Translational Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Concordia University","funders":"Agence Nationale de la Recherche; Fondation Leducq; Fondation de l'Avenir pour la Recherche Médicale Appliquée","keywords":"CADASIL; Medicine; Neurovascular bundle; Coupling (piping); Dynamics (music); Pathology; Leukoencephalopathy; Disease","authors":[{"name":"Clément Huneau","is_ca":false},{"name":"Marion Houot","is_ca":false},{"name":"Anne Joutel","is_ca":false},{"name":"Benoît Béranger","is_ca":false},{"name":"Christian Giroux","is_ca":false},{"name":"Habib Benali","is_ca":true},{"name":"Hugues Chabriat","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08402402951125107,"gpt":0.3951091293763663,"spread":0.3110850998651152,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003969351,0.0004139502,0.0002739945,0.001219618,0.0003056609,0.0003928411,0.0001743248,0.0004087151,0.001579516],"category_scores_gemma":[0.001270865,0.0001764833,0.0001346254,0.0003430538,0.0005828886,0.0002122202,0.0002760755,0.0003503851,0.0001494345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003389203,"about_ca_system_score_gemma":0.0001250987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001077663,"about_ca_topic_score_gemma":0.001291681,"domain_scores_codex":[0.9998529,0.00002620104,0.00001884075,0.00004302356,0.00003033423,0.0000287015],"domain_scores_gemma":[0.9994967,0.0001613823,0.0001669115,0.00004169391,0.00005321515,0.00008006647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004743142,0.0002755497,0.7089714,0.0001894656,0.0002231008,0.02438628,0.002698994,0.00165336,0.2291791,0.0002858851,0.0003543197,0.02703939],"study_design_scores_gemma":[0.00003538307,0.0009174892,0.9741921,0.00001596229,0.00007542718,0.01228799,0.0002692243,0.0008529781,0.01088568,0.0002522268,0.0001988918,0.00001660551],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993913,0.0001144868,0.000238733,0.000008120805,0.000002216688,0.00000336672,0.00004561926,0.000009302809,0.0001868052],"genre_scores_gemma":[0.9997155,0.00005221871,0.00009947101,0.000008965018,0.000004209937,0.00000241116,0.00006560365,0.000001659037,0.00004993552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001579516,"threshold_uncertainty_score":0.005284011,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4239279510","doi":"10.1176/jnp.2008.20.2.150","title":"Comparability of the Clinical Diagnostic Criteria for Vascular Dementia: A Critical Review. Part I","year":2008,"lang":"en","type":"review","venue":"Journal of Neuropsychiatry","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"","keywords":"Comparability; Dementia; Vascular dementia; Medicine; Intensive care medicine; Pathology; Disease","authors":[{"name":"Sandra Wiederkehr","is_ca":true},{"name":"Martine Simard","is_ca":false},{"name":"Claudette Fortin","is_ca":false},{"name":"Robert van Reekum","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1158296108210122,"gpt":0.4462638592315457,"spread":0.3304342484105335,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01292901,0.000946103,0.005014577,0.007777559,0.0005094276,0.00219844,0.002132877,0.001475303,0.001281843],"category_scores_gemma":[0.035772,0.0005866161,0.001566855,0.006872892,0.001414507,0.002432384,0.0009702154,0.001503816,0.0004564877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002319062,"about_ca_system_score_gemma":0.005358587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003206073,"about_ca_topic_score_gemma":0.004465274,"domain_scores_codex":[0.9934536,0.002436658,0.002314834,0.000690594,0.0009890887,0.0001152567],"domain_scores_gemma":[0.9785424,0.01540295,0.002107338,0.0003849621,0.003390739,0.0001716063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0002028987,0.00004359474,0.002012802,0.09763901,0.00106204,0.0003174979,0.0003346498,0.0001361848,0.0004199635,0.002405807,0.02208696,0.8733385],"study_design_scores_gemma":[0.0003286511,0.0008040561,0.02828998,0.2692558,0.007169547,0.008819673,0.002705336,0.0004676561,0.001339302,0.00698703,0.6736172,0.0002157214],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001599812,0.9989274,0.00008892662,0.0003533458,0.0002940948,0.00001178626,0.00002097547,0.000001963319,0.0001415036],"genre_scores_gemma":[0.004133936,0.9933402,0.00108155,0.0007452103,0.000419656,0.00007448973,0.0001346376,0.000003219536,0.00006715546],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01292901,"threshold_uncertainty_score":0.06837595,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2161791602","doi":"10.1161/01.str.0000195177.61184.49","title":"Genetics of Vascular Cognitive Impairment","year":2005,"lang":"en","type":"review","venue":"Stroke","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Baycrest Hospital; London Health Sciences Centre; Western University","funders":"","keywords":"Medicine; Gene; Disease; Cognitive impairment; Phenotype; Cognition; Neuroscience; Genetics; Pathology; Biology; Psychiatry","authors":[{"name":"Gabrielle G. Leblanc","is_ca":true},{"name":"James F. Meschia","is_ca":true},{"name":"Donald T. Stuss","is_ca":true},{"name":"Vladimir Hachinski","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02556751376101423,"gpt":0.328578917737698,"spread":0.3030114039766838,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003635754,0.0007661493,0.001298137,0.001513551,0.000222393,0.0006736622,0.0006372259,0.0008580912,0.002046425],"category_scores_gemma":[0.0007184788,0.0001280004,0.0003468729,0.001245476,0.0005439895,0.0004672233,0.0003381406,0.0006571433,0.001112044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004788821,"about_ca_system_score_gemma":0.0009788298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002129062,"about_ca_topic_score_gemma":0.001620545,"domain_scores_codex":[0.9998474,0.00003599982,0.00001881368,0.00003756879,0.00004391353,0.00001630085],"domain_scores_gemma":[0.9998083,0.00008584619,0.00003925305,0.000007677057,0.00004381212,0.00001521556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009436771,0.00005314151,0.003672358,0.008770553,0.0002678832,0.003028888,0.0001814681,0.0007907139,0.002538836,0.008665551,0.03180356,0.9401327],"study_design_scores_gemma":[0.00004945094,0.0001555125,0.02050359,0.01055495,0.0004457109,0.05240076,0.0003015358,0.0002785262,0.001740616,0.0156153,0.8978876,0.00006645302],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008371975,0.9950292,0.0003604126,0.0007445784,0.0002147273,0.000006762648,0.00003775825,0.00001634197,0.002753107],"genre_scores_gemma":[0.00614509,0.9918752,0.0003935549,0.0003085319,0.0003043952,0.00001035233,0.00006826041,0.000002286846,0.0008921956],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002129062,"threshold_uncertainty_score":0.006846011,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3039378818","doi":"10.1186/s40478-020-00972-z","title":"Disturbed balance in the expression of MMP9 and TIMP3 in cerebral amyloid angiopathy-related intracerebral haemorrhage","year":2020,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institutes of Health; Alzheimer Nederland; Hartstichting; ZonMw; Weston Brain Institute","keywords":"Cerebral amyloid angiopathy; Neurology; Medicine; Balance (ability); Amyloid (mycology); Pathology; Neuroscience; Psychology; Physical medicine and rehabilitation; Dementia; Psychiatry","authors":[{"name":"Lieke Jäkel","is_ca":false},{"name":"H. Bea Kuiperij","is_ca":false},{"name":"Lara P. Gerding","is_ca":false},{"name":"Emma E. M. Custers","is_ca":false},{"name":"E. van den Berg","is_ca":false},{"name":"Wilmar M.T. Jolink","is_ca":false},{"name":"Floris H.B.M. Schreuder","is_ca":false},{"name":"Benno Küsters","is_ca":false},{"name":"Catharina J.M. Klijn","is_ca":false},{"name":"Marcel M. Verbeek","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02580527180023072,"gpt":0.2615741560968991,"spread":0.2357688842966684,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001454487,0.0001803029,0.0002277437,0.0008117313,0.0001773789,0.0003127992,0.0001152854,0.0002291311,0.0006351029],"category_scores_gemma":[0.000289243,0.0001507392,0.0002028285,0.0004175149,0.0002765152,0.0001803591,0.0001751996,0.0002667921,0.0002021535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001580034,"about_ca_system_score_gemma":0.00008404651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006879088,"about_ca_topic_score_gemma":0.0006728952,"domain_scores_codex":[0.999915,0.00001254048,0.00001362853,0.00001718316,0.00002221593,0.00001945624],"domain_scores_gemma":[0.9998127,0.00002417865,0.00009168392,0.00001092536,0.00002704615,0.00003358637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002195911,0.0001161037,0.1318913,0.0001795368,0.0001030098,0.004908721,0.0004016249,0.00008612864,0.8524977,0.0001036257,0.0001517221,0.007364529],"study_design_scores_gemma":[0.00003349585,0.0002552636,0.9423164,0.0000138879,0.00006957262,0.008596817,0.0002967903,0.0003977809,0.04703686,0.0002110848,0.0007597884,0.00001225087],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980924,0.001163419,0.0002798255,0.00001785338,0.000006090248,0.000005914997,0.00006938861,0.00000622347,0.0003589531],"genre_scores_gemma":[0.998781,0.0005613695,0.0002739207,0.0000141727,0.000009160002,0.000007968662,0.00008825615,0.000001813102,0.0002622671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008117313,"threshold_uncertainty_score":0.002124667,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1978994585","doi":"10.1159/000051256","title":"Mutations of the Notch3 Gene in Non-Caucasian Patients with Suspected CADASIL Syndrome","year":2001,"lang":"en","type":"article","venue":"Dementia and Geriatric Cognitive Disorders","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal General Hospital","funders":"Ministry of Culture and Sport","keywords":"CADASIL; Leukoencephalopathy; Missense mutation; Mutation; Genetics; Medicine; Pathology; Disease; Biology; Gene","authors":[{"name":"Satoshi Kotorii","is_ca":false},{"name":"Keikichi Takahashi","is_ca":false},{"name":"Kohei Kamimura","is_ca":false},{"name":"Takeshi Nishio","is_ca":false},{"name":"Kunimasa Arima","is_ca":false},{"name":"Haruki Yamada","is_ca":false},{"name":"Eiichiro Uyama","is_ca":false},{"name":"Makoto Uchino","is_ca":false},{"name":"Akihito Suenaga","is_ca":false},{"name":"Masayasu Matsumoto","is_ca":false},{"name":"George A. Kuchel","is_ca":false},{"name":"Guy A. Rouleau","is_ca":true},{"name":"Takeshi Tabira","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.002567426169214851,"gpt":0.2015150855752795,"spread":0.1989476594060647,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005003161,0.0009955558,0.0005351117,0.001728935,0.001800717,0.0005476194,0.0003684317,0.0009900716,0.002565257],"category_scores_gemma":[0.002695184,0.0003956568,0.0003627908,0.0009596444,0.0006891015,0.0002513969,0.0004491748,0.0003329837,0.0004370054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003861928,"about_ca_system_score_gemma":0.0004169156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004448738,"about_ca_topic_score_gemma":0.007226401,"domain_scores_codex":[0.9995387,0.00009227572,0.00008817094,0.0001088828,0.00009565272,0.00007636864],"domain_scores_gemma":[0.9992975,0.0001939039,0.0001538754,0.00005111481,0.0001053111,0.0001982649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009551244,0.0003033977,0.8034289,0.00009135237,0.0001694481,0.1582947,0.002546564,0.000177626,0.02334836,0.0002540064,0.0008241052,0.009606475],"study_design_scores_gemma":[0.0001469139,0.0005339019,0.7241662,0.00005646517,0.0002095146,0.2675845,0.001457772,0.0006836865,0.003350275,0.0003511239,0.001416978,0.0000425842],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991787,0.0001780226,0.00008071548,0.00005115515,0.000006984892,0.000008143659,0.00004546043,0.00000746058,0.0004432847],"genre_scores_gemma":[0.9993827,0.0001229979,0.0001202349,0.00007702865,0.00001978174,0.000005324144,0.0001044141,0.000004401219,0.0001630368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004448738,"threshold_uncertainty_score":0.008845687,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3009246199","doi":"10.1161/strokeaha.119.028840","title":"Global Assessment of Mendelian Stroke Genetic Prevalence in 101 635 Individuals From 7 Ethnic Groups","year":2020,"lang":"en","type":"article","venue":"Stroke","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; Population Health Research Institute","funders":"Medical Research Council","keywords":"Nonsynonymous substitution; Medicine; Genetics; Mendelian inheritance; In silico; Ethnic group; Gene; Biology; Genome","authors":[{"name":"Nickrooz Grami","is_ca":true},{"name":"Michael Chong","is_ca":true},{"name":"Ricky Lali","is_ca":true},{"name":"Pedrum Mohammadi‐Shemirani","is_ca":true},{"name":"David Henshall","is_ca":false},{"name":"Kristiina Rannikmäe","is_ca":false},{"name":"Guillaume Paré","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02489888739982414,"gpt":0.3127142079432924,"spread":0.2878153205434682,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001367545,0.0003627628,0.0005523326,0.001674278,0.0005057472,0.0005402752,0.000359473,0.0005590117,0.001431243],"category_scores_gemma":[0.002290924,0.0002338177,0.0004086373,0.001313462,0.0002872134,0.0003285912,0.0005961515,0.0003011778,0.0003111467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000226672,"about_ca_system_score_gemma":0.0001564419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004522651,"about_ca_topic_score_gemma":0.003891219,"domain_scores_codex":[0.9991925,0.0002480642,0.0001122895,0.0002488806,0.0001339161,0.00006426217],"domain_scores_gemma":[0.9987369,0.0003125102,0.000452934,0.0001564084,0.0001852619,0.0001560444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009739084,0.00001360584,0.9968655,0.00001339125,0.00009161692,0.00009826643,0.0001237314,0.0000577058,0.0003573006,0.00001503825,0.0001146622,0.002151877],"study_design_scores_gemma":[0.000008180396,0.00007065469,0.9984571,0.000006265741,0.0000449911,0.0006332395,0.0001587662,0.0002638241,0.00009538879,0.00004069855,0.0002163952,0.000004549274],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982718,0.000215035,0.0002308792,0.00002121589,0.000003172552,0.00001595546,0.0008788675,0.00001214962,0.0003509855],"genre_scores_gemma":[0.9977086,0.000137532,0.0003548565,0.00002151355,0.00000591494,0.00002670226,0.001548571,0.00000345804,0.0001928481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004522651,"threshold_uncertainty_score":0.008992672,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4281391589","doi":"10.1212/wnl.0000000000200607","title":"Prevalence and Predictors of Vascular Cognitive Impairment in Patients With CADASIL","year":2022,"lang":"en","type":"article","venue":"Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Medical Research Council; University College London Hospitals NHS Foundation Trust; Cambridge University Hospitals; University College London; University of Cambridge; British Heart Foundation","keywords":"CADASIL; Leukoencephalopathy; Medicine; Montreal Cognitive Assessment; Dementia; Internal medicine; Stroke (engine); Cognitive impairment; Oncology; Disease","authors":[{"name":"Amy A. Jolly","is_ca":false},{"name":"Stefania Nannoni","is_ca":false},{"name":"Hayley Edwards","is_ca":false},{"name":"Robin G. Morris","is_ca":false},{"name":"Hugh S. Markus","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003223910007043476,"gpt":0.1965240784065178,"spread":0.1933001683994743,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004387232,0.0004164604,0.0004309622,0.001178699,0.0005939458,0.0007046849,0.0003247583,0.0006353135,0.001502133],"category_scores_gemma":[0.001659639,0.0002280631,0.0004738058,0.0009669349,0.0003712865,0.0003663872,0.0004063685,0.000631655,0.000174321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003293906,"about_ca_system_score_gemma":0.00024086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007345006,"about_ca_topic_score_gemma":0.007750441,"domain_scores_codex":[0.9997116,0.00003894319,0.000045762,0.00007524242,0.00007051674,0.0000578981],"domain_scores_gemma":[0.9988419,0.0001853254,0.0005322024,0.00005591358,0.0001332812,0.0002513385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001455594,0.00002278995,0.9984231,0.000006878692,0.00004441673,0.0002408981,0.00004533651,0.00003111069,0.0001560211,0.000008656775,0.00004711644,0.0008281473],"study_design_scores_gemma":[0.000005632882,0.0000630541,0.9989354,0.000004705682,0.00001971384,0.0007273646,0.0000680407,0.00009164523,0.00002925942,0.00002243113,0.00003027228,0.000002463701],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992441,0.0002673909,0.00002119653,0.00003263044,0.000004646,0.000003045989,0.0001146804,0.000003464931,0.0003088196],"genre_scores_gemma":[0.999733,0.0000558947,0.0000169854,0.00001350168,0.000009714072,0.000001126472,0.0001347003,5.561088e-7,0.00003438562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007345006,"threshold_uncertainty_score":0.01460451,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2911065305","doi":"10.3389/fpsyt.2018.00741","title":"Effects of Cerebral Blood Flow and White Matter Integrity on Cognition in CADASIL Patients","year":2019,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"CADASIL; Cerebral blood flow; Cognition; White matter; Leukoencephalopathy; Medicine; Neuroscience; Psychology; Cardiology; Internal medicine; Magnetic resonance imaging; Radiology; Disease","authors":[{"name":"Xinzhen Yin","is_ca":false},{"name":"Ying Zhou","is_ca":false},{"name":"Shenqiang Yan","is_ca":false},{"name":"Min Lou","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.001780974203658681,"gpt":0.1936217533894052,"spread":0.1918407791857465,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005519344,0.0004371335,0.000429471,0.001730146,0.0005192467,0.0005612923,0.0002101881,0.0004464741,0.001564523],"category_scores_gemma":[0.00195961,0.0001776044,0.0003750587,0.0006030173,0.0005444903,0.0003318097,0.0002550021,0.0003513595,0.0002117006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003968651,"about_ca_system_score_gemma":0.000199824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002491657,"about_ca_topic_score_gemma":0.003663877,"domain_scores_codex":[0.9997717,0.0000365851,0.00004049447,0.00006672107,0.00004619342,0.00003832503],"domain_scores_gemma":[0.9987937,0.0003129846,0.0004933221,0.00007763234,0.000128047,0.0001943825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000691755,0.00003753995,0.992977,0.00002243557,0.0001184663,0.0014137,0.000158967,0.00009368361,0.001382613,0.00002092997,0.00006324452,0.003019661],"study_design_scores_gemma":[0.00000786593,0.0001915167,0.9981592,0.000008282975,0.00004858222,0.001176113,0.00006685287,0.00009197427,0.0001676629,0.00003292285,0.00004514997,0.000003975849],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993519,0.0002635669,0.00003425866,0.00001787919,0.000003187026,0.00000324251,0.0001071236,0.000003274958,0.0002155389],"genre_scores_gemma":[0.9995995,0.0001013011,0.00004513761,0.00001425772,0.000009933136,0.000002258633,0.0001866819,9.047773e-7,0.00004010991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002491657,"threshold_uncertainty_score":0.005233884,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2059090669","doi":"10.1016/s0006-3223(03)00588-2","title":"NOTCH4 gene haplotype is associated with schizophrenia in African Americans","year":2003,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Center for Research Resources; National Institute on Drug Abuse; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism","keywords":"Haplotype; Single-nucleotide polymorphism; Linkage disequilibrium; Allele; Locus (genetics); Genetics; Allele frequency; Biology; Exact test; Genotype; Medicine; Internal medicine; Gene","authors":[{"name":"Xingguang Luο","is_ca":false},{"name":"Tim Klempan","is_ca":true},{"name":"Jaakko Lappalainen","is_ca":false},{"name":"Robert A. Rosenheck","is_ca":false},{"name":"Dennis S. Charney","is_ca":false},{"name":"Joseph Erdos","is_ca":false},{"name":"Daniël P. van Kammen","is_ca":false},{"name":"Henry R. Kranzler","is_ca":false},{"name":"James L. Kennedy","is_ca":true},{"name":"Joel Gelernter","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0226386254970031,"gpt":0.2547547008373512,"spread":0.2321160753403481,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002591921,0.0004840998,0.0003328098,0.001340395,0.001341401,0.0003613376,0.0003346963,0.0005457308,0.004961743],"category_scores_gemma":[0.001137636,0.0002523972,0.0003511109,0.0009231116,0.0004300718,0.000287171,0.0003313292,0.0004653104,0.0002319134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002073437,"about_ca_system_score_gemma":0.0002630612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005898412,"about_ca_topic_score_gemma":0.006268981,"domain_scores_codex":[0.9997593,0.0000790303,0.00002863683,0.00005214594,0.00002731746,0.00005364436],"domain_scores_gemma":[0.9994754,0.0001602986,0.0001778803,0.00003162532,0.0000380389,0.000116738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002998737,0.0003300355,0.9270888,0.00005699308,0.0003311513,0.009163157,0.001996208,0.0001191234,0.05159255,0.0007006336,0.0003901095,0.005232524],"study_design_scores_gemma":[0.0000968033,0.0003961667,0.9832644,0.0000455947,0.0002644479,0.01100161,0.001639804,0.0004868544,0.001664422,0.0004899597,0.0006214711,0.0000283849],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995391,0.00005271944,0.00005451991,0.00004659161,0.000006143817,0.000002043675,0.00005177841,0.000001502904,0.0002455429],"genre_scores_gemma":[0.9994202,0.00005703676,0.0001421836,0.00004334058,0.00001027622,0.00000330584,0.00004232908,0.000003407866,0.0002779823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005898412,"threshold_uncertainty_score":0.01659864,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4399327057","doi":"10.1161/circresaha.124.324327","title":"Cerebrovascular Effects of Sildenafil in Small Vessel Disease: The OxHARP Trial","year":2024,"lang":"en","type":"article","venue":"Circulation Research","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"NIHR Oxford Biomedical Research Centre; Alzheimer's Society; University of Oxford; National Institute for Health and Care Research; Alzheimer Society; Wellcome Trust","keywords":"Sildenafil; Cilostazol; Medicine; Cardiology; cGMP-specific phosphodiesterase type 5; Internal medicine; Perfusion; Vascular disease; Cerebral circulation; Aspirin","authors":[{"name":"Alastair J.S. Webb","is_ca":false},{"name":"Jacqueline Birks","is_ca":false},{"name":"Karolina A Feakins","is_ca":false},{"name":"Amy Lawson","is_ca":false},{"name":"Jesse Dawson","is_ca":false},{"name":"Alexander Rothman","is_ca":false},{"name":"David J. Werring","is_ca":false},{"name":"Osian Llwyd","is_ca":false},{"name":"Catriona Stewart","is_ca":false},{"name":"James Thomas","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04877477208549517,"gpt":0.3613949066562788,"spread":0.3126201345707836,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001275868,0.0007358312,0.001419511,0.000149809,0.0003062673,0.0008675837,0.0004168986,0.0007869817,0.003761062],"category_scores_gemma":[0.001142123,0.0002208187,0.0007971929,0.000267404,0.0004218631,0.0004273329,0.0002857064,0.001406291,0.0002106969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003256518,"about_ca_system_score_gemma":0.0005855195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008784679,"about_ca_topic_score_gemma":0.002186232,"domain_scores_codex":[0.9996452,0.0001914818,0.00001810557,0.00005205678,0.00003310963,0.00006000642],"domain_scores_gemma":[0.9995733,0.0001258177,0.0001127444,0.00002918983,0.00002859617,0.0001303368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9120594,0.002784655,0.01198494,0.004056466,0.004332251,0.0002482795,0.0001524033,0.0009363565,0.003290429,0.0007475148,0.007132623,0.05227463],"study_design_scores_gemma":[0.8638596,0.04720515,0.0666779,0.0007577158,0.01043496,0.000278695,0.0001363442,0.001807271,0.0008962851,0.001254468,0.006639624,0.0000520481],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756063,0.01840034,0.0002457091,0.0009935335,0.0003866732,0.0003685134,0.0009228273,0.00003422355,0.003042025],"genre_scores_gemma":[0.986484,0.00730589,0.0004892831,0.001202578,0.0005800896,0.0006566384,0.001080132,0.00001057577,0.002190733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003761062,"threshold_uncertainty_score":0.012582,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3153603374","doi":"10.1016/j.ajpath.2021.03.015","title":"Notch3 Signaling and Aggregation as Targets for the Treatment of CADASIL and Other NOTCH3-Associated Small-Vessel Diseases","year":2021,"lang":"en","type":"review","venue":"American Journal Of Pathology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute on Aging; Universitätsklinikum Hamburg-Eppendorf; National Institutes of Health; Fonds de Recherche du Québec - Santé; Massachusetts General Hospital; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"CADASIL; Leukoencephalopathy; Notch signaling pathway; Biology; Medicine; Signal transduction; Pathology; Disease; Genetics","authors":[{"name":"Dorothée Schoemaker","is_ca":false},{"name":"Joseph F. Arboleda‐Velásquez","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02769430025592395,"gpt":0.3270190432231895,"spread":0.2993247429672655,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007508215,0.00092376,0.002210781,0.002008073,0.0002122465,0.001025747,0.001193822,0.001131247,0.002897125],"category_scores_gemma":[0.0007464841,0.0002499817,0.0007178666,0.001491851,0.0003340467,0.0009543388,0.0005961887,0.002199351,0.00145057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004392944,"about_ca_system_score_gemma":0.0008125494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009362841,"about_ca_topic_score_gemma":0.002172523,"domain_scores_codex":[0.9998289,0.00003018247,0.0000301062,0.00002680266,0.00006506171,0.00001875951],"domain_scores_gemma":[0.9996951,0.0001397734,0.00005046138,0.000007819157,0.000078446,0.00002858825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002170773,0.0001088807,0.0001438294,0.01597854,0.0002543139,0.0003023257,0.00004176021,0.0004399916,0.001602119,0.001972675,0.02796033,0.9509782],"study_design_scores_gemma":[0.0001939862,0.0003448709,0.001418566,0.007853716,0.0008748086,0.00206312,0.00008095762,0.0003341186,0.001024468,0.002531027,0.9832292,0.00005110903],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000117918,0.9992131,0.00008360967,0.0001282116,0.0001301036,0.000003529372,0.00001597768,0.000005909104,0.0003015897],"genre_scores_gemma":[0.0006799944,0.9984469,0.0001715593,0.0001914435,0.0001667792,0.000005170838,0.00004421981,0.000001638501,0.0002924339],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002897125,"threshold_uncertainty_score":0.009691834,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3097942751","doi":"10.1097/cm9.0000000000001176","title":"HTRA1-related autosomal dominant cerebral small vessel disease","year":2020,"lang":"en","type":"article","venue":"Chinese Medical Journal","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"CAE (Canada)","funders":"","keywords":"Proband; Missense mutation; Leukoencephalopathy; Genetics; Medicine; CADASIL; Disease; Pathology; Mutation; Biology; Internal medicine; Gene","authors":[{"name":"Jingyi Liu","is_ca":false},{"name":"Yi‐Cheng Zhu","is_ca":true},{"name":"Lixin Zhou","is_ca":true},{"name":"Yanping Wei","is_ca":true},{"name":"Chenhui Mao","is_ca":true},{"name":"Liying Cui","is_ca":true},{"name":"Bin Peng","is_ca":true},{"name":"Ming Yao","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009781018010595187,"gpt":0.2494487737776273,"spread":0.2396677557670321,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001750073,0.0002534435,0.0002966699,0.001207555,0.0002232858,0.0002335777,0.00023086,0.0001847099,0.001723099],"category_scores_gemma":[0.000479771,0.0000883121,0.000251215,0.00122141,0.0002184428,0.0001783837,0.000177004,0.0001103282,0.0002742972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001938947,"about_ca_system_score_gemma":0.0003082528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008200001,"about_ca_topic_score_gemma":0.00093064,"domain_scores_codex":[0.9998671,0.00001341521,0.00002915767,0.00003477053,0.0000334848,0.00002198377],"domain_scores_gemma":[0.9996735,0.00008422429,0.0001672285,0.00001797498,0.00002748265,0.00002964993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"case_report","study_design_scores_codex":[0.0005298898,0.00008010385,0.7660787,0.002513055,0.0006717319,0.1315943,0.0008027121,0.0002870134,0.02949003,0.0004822089,0.001095951,0.0663743],"study_design_scores_gemma":[0.00004742893,0.0003475023,0.7150971,0.0001726605,0.0005523541,0.2711559,0.0002382018,0.0002492416,0.005811785,0.000350787,0.005958604,0.00001846225],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788776,0.01867926,0.0003185328,0.00004822227,0.00001638337,0.00002352449,0.0003044395,0.00001648739,0.001715582],"genre_scores_gemma":[0.9922218,0.006704446,0.0002385738,0.00004295289,0.00003955512,0.00001083164,0.0003935282,0.000002284268,0.0003461454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001723099,"threshold_uncertainty_score":0.005764365,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2031337122","doi":"10.1177/0883073810361382","title":"Childhood-Onset CADASIL: Clinical, Imaging, and Neurocognitive Features","year":2010,"lang":"en","type":"article","venue":"Journal of Child Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"CADASIL; Leukoencephalopathy; Neurocognitive; Hyperintensity; Dementia; Migraine with aura; Psychology; Migraine; Magnetic resonance imaging; Medicine; Family history; Disease; Neuroscience; Psychiatry; Cognition; Pathology; Aura; Internal medicine; Radiology","authors":[{"name":"Jessica N. Hartley","is_ca":true},{"name":"Robyn Westmacott","is_ca":true},{"name":"Jochen Decker","is_ca":false},{"name":"Manohar Shroff","is_ca":true},{"name":"Grace Yoon","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005449771148192714,"gpt":0.2817818173684845,"spread":0.2763320462202918,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766311,0.001328073,0.0007014588,0.001045822,0.00100884,0.0004444403,0.0003066343,0.001161528,0.002157336],"category_scores_gemma":[0.001246755,0.0003776435,0.0002193111,0.0007494825,0.0009440653,0.0006645144,0.0005022383,0.001152053,0.000393257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005617935,"about_ca_system_score_gemma":0.000709209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007922565,"about_ca_topic_score_gemma":0.01193674,"domain_scores_codex":[0.9998037,0.00001835389,0.00002220704,0.00004686691,0.00003873427,0.00007013771],"domain_scores_gemma":[0.9992113,0.0002212536,0.0001394063,0.00002770291,0.00006897716,0.0003313415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001413641,0.000144937,0.1484068,0.00009372057,0.0000206718,0.8373017,0.001507696,0.000266579,0.005628374,0.0003115878,0.000899636,0.005276921],"study_design_scores_gemma":[0.00001876614,0.0002833645,0.2337123,0.00004113968,0.00003366916,0.7627963,0.0006939251,0.0001937889,0.0008656337,0.0001504794,0.001189398,0.00002112097],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939142,0.0007526047,0.0003635919,0.0004199584,0.00004427864,0.00003871414,0.0003560234,0.00005980669,0.004050732],"genre_scores_gemma":[0.9973366,0.0007554422,0.0006051254,0.0001950672,0.00009786152,0.00001603994,0.000252378,0.00001518964,0.0007264511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007922565,"threshold_uncertainty_score":0.01575291,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2993044950","doi":"10.1097/wco.0000000000000786","title":"RNA expression studies in stroke: what can they tell us about stroke mechanism?","year":2019,"lang":"en","type":"review","venue":"Current Opinion in Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Stroke (engine); Medicine; Biomarker; Mechanism (biology); microRNA; Bioinformatics; Gene; Biology; Genetics","authors":[{"name":"Sarina Falcione","is_ca":true},{"name":"Joseph Kamtchum‐Tatuene","is_ca":true},{"name":"Gina Sykes","is_ca":true},{"name":"Glen C. Jickling","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1414369918129807,"gpt":0.417153829896162,"spread":0.2757168380831813,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001399936,0.0009514377,0.002651991,0.002291663,0.0003328463,0.001606778,0.001320236,0.002167801,0.004201633],"category_scores_gemma":[0.003893772,0.0003632317,0.0009502383,0.002448158,0.001002979,0.002891917,0.0007915107,0.002331489,0.002968438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008563272,"about_ca_system_score_gemma":0.001939758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001383952,"about_ca_topic_score_gemma":0.001417652,"domain_scores_codex":[0.9995912,0.0001098196,0.00008322556,0.0000742001,0.0001099583,0.00003163426],"domain_scores_gemma":[0.997997,0.001339866,0.0001946105,0.00004803727,0.0003435222,0.00007701375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000129418,0.00003419312,0.0003199178,0.05798285,0.0002568863,0.0002642203,0.0001298709,0.0002614872,0.0009239254,0.005406411,0.07836009,0.8559306],"study_design_scores_gemma":[0.000018717,0.00007313277,0.00121128,0.01916059,0.0003071526,0.001338666,0.0001460627,0.0000792596,0.0002804551,0.004856422,0.9724919,0.00003640839],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002517284,0.9984275,0.00005935038,0.0006989699,0.0004558989,0.00000254266,0.00001638636,0.000004411552,0.0003098279],"genre_scores_gemma":[0.0002055031,0.9987866,0.00006573029,0.0003745899,0.0003830007,0.000004550029,0.00001853499,0.000001453262,0.0001600911],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004201633,"threshold_uncertainty_score":0.01405585,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3081219311","doi":"10.1161/strokeaha.120.029517","title":"Beyond the Brain","year":2020,"lang":"en","type":"review","venue":"Stroke","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Natural Sciences and Engineering Research Council of Canada; McMaster University","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Phenotype; Medicine; Stroke (engine); Gene; Disease; Bioinformatics; Internal medicine; Pathology; Genetics; Biology","authors":[{"name":"Kristiina Rannikmäe","is_ca":false},{"name":"David Henshall","is_ca":false},{"name":"Sophie Thrippleton","is_ca":false},{"name":"Qiu Ginj Kong","is_ca":false},{"name":"Mike Chong","is_ca":true},{"name":"Nickrooz Grami","is_ca":true},{"name":"Isaac Kuan","is_ca":false},{"name":"Tim Wilkinson","is_ca":false},{"name":"Blair Wilson","is_ca":false},{"name":"Kirsty Wilson","is_ca":false},{"name":"Guillaume Paré","is_ca":true},{"name":"Cathie Sudlow","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0228113965410339,"gpt":0.3132178225605069,"spread":0.290406426019473,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001480048,0.0006702991,0.001094071,0.001568786,0.0008917694,0.005048803,0.00108367,0.002153423,0.03975286],"category_scores_gemma":[0.004938236,0.0001948702,0.000788181,0.001392654,0.002267764,0.004324643,0.002460416,0.002545956,0.01482995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001477442,"about_ca_system_score_gemma":0.004287522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002981693,"about_ca_topic_score_gemma":0.003255954,"domain_scores_codex":[0.9988021,0.0004751642,0.00009945881,0.0002314164,0.000267445,0.000124473],"domain_scores_gemma":[0.998215,0.0006175289,0.0002525407,0.000185803,0.0005134845,0.0002157876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002830277,0.00005424903,0.003911039,0.008752434,0.0005982868,0.001465405,0.00103094,0.0002995749,0.001304276,0.08761901,0.3182572,0.5764244],"study_design_scores_gemma":[0.00003766745,0.00008329422,0.003183305,0.007597607,0.0001954524,0.003217348,0.0005514285,0.00006928171,0.0003389111,0.04649589,0.9381973,0.00003246822],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005910758,0.6877167,0.005744536,0.06764542,0.009653263,0.0001061973,0.003310817,0.0004129978,0.2194992],"genre_scores_gemma":[0.1481928,0.6863017,0.00784439,0.0615999,0.01498273,0.0003983866,0.004256949,0.0004114994,0.07601172],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03975286,"threshold_uncertainty_score":0.1329866,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2965072854","doi":"10.1016/j.neuroscience.2019.07.048","title":"Altered Brain Glucose Metabolism Assessed by 18F-FDG PET Imaging Is Associated with the Cognitive Impairment of CADASIL","year":2019,"lang":"en","type":"article","venue":"Neuroscience","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Program of Shanghai Academic Research Leader; National Natural Science Foundation of China","keywords":"CADASIL; Leukoencephalopathy; Internal medicine; Medicine; Carbohydrate metabolism; Neuroscience; Positron emission tomography; Psychology; Montreal Cognitive Assessment; Endocrinology; Frontal lobe; White matter; Cognition; Cognitive impairment; Magnetic resonance imaging; Radiology","authors":[{"name":"Jingjing Su","is_ca":false},{"name":"Qi Huang","is_ca":false},{"name":"Shuhua Ren","is_ca":false},{"name":"Fang Xie","is_ca":false},{"name":"Yu Zhai","is_ca":false},{"name":"Yihui Guan","is_ca":false},{"name":"Jian‐Ren Liu","is_ca":false},{"name":"Fengchun Hua","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006788287802763951,"gpt":0.249015408413548,"spread":0.2422271206107841,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000362001,0.0008736528,0.0006200203,0.002292114,0.0006051686,0.0008911692,0.0004993306,0.0008677366,0.001758138],"category_scores_gemma":[0.001393829,0.0002829031,0.0003928122,0.001299864,0.000728514,0.0003931998,0.0003259451,0.0006284754,0.0002443521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003849611,"about_ca_system_score_gemma":0.0003016551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00402969,"about_ca_topic_score_gemma":0.003193542,"domain_scores_codex":[0.9997835,0.00002910865,0.00003801276,0.00004586736,0.00005538942,0.0000481149],"domain_scores_gemma":[0.999153,0.0001906907,0.0003825307,0.0000469779,0.00008324693,0.0001434723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001869816,0.000271807,0.9531057,0.00009496015,0.0003068938,0.02277577,0.0003470717,0.0002338214,0.01169138,0.0001579297,0.0002329658,0.008911864],"study_design_scores_gemma":[0.00001043667,0.0001721916,0.9866955,0.00001192995,0.00008589653,0.01155263,0.0001378298,0.0002531194,0.0007734021,0.0002055571,0.00009365223,0.000007882094],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979591,0.0006716001,0.0001414111,0.00006824174,0.00001238452,0.000004349794,0.0001139757,0.00001433709,0.001014506],"genre_scores_gemma":[0.9994911,0.0001862838,0.00006540945,0.00002604366,0.00002077447,0.000001610613,0.0001061579,0.000001934912,0.0001006814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00402969,"threshold_uncertainty_score":0.008012474,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3037390891","doi":"10.1002/mds.28171","title":"Parkinson's Disease, <scp><i>NOTCH3</i></scp> Genetic Variants, and White Matter Hyperintensities","year":2020,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Toronto Western Hospital; Occupational Cancer Research Centre; Ottawa Hospital; Health Sciences Centre; Queen's University; Nova Scotia Health Authority; Canadian Celiac Association; University of Ottawa; Ontario Brain Institute; Baycrest Hospital; Dalhousie University; University of Toronto; Western University; Sunnybrook Health Science Centre","funders":"Wellcome Trust; Ontario Brain Institute","keywords":"Hyperintensity; White matter; Parkinson's disease; Disease; Medicine; Magnetic resonance imaging; Psychology; Cohort; Cognitive decline; Population; Neuroscience; Cardiology; Internal medicine; Dementia; Radiology","authors":[{"name":"Joel Ramirez","is_ca":true},{"name":"Allison A. Dilliott","is_ca":true},{"name":"Malcolm A. Binns","is_ca":true},{"name":"David P. Breen","is_ca":false},{"name":"Emily C. Evans","is_ca":true},{"name":"Derek Beaton","is_ca":true},{"name":"Paula McLaughlin","is_ca":true},{"name":"Donna Kwan","is_ca":true},{"name":"Melissa F. Holmes","is_ca":true},{"name":"Miracle Ozzoude","is_ca":true},{"name":"Christopher J.M. Scott","is_ca":true},{"name":"Stephen C. Strother","is_ca":true},{"name":"Sean Symons","is_ca":true},{"name":"Richard H. Swartz","is_ca":true},{"name":"David A. Grimes","is_ca":true},{"name":"Mandar Jog","is_ca":true},{"name":"Mario Masellis","is_ca":true},{"name":"Sandra E. Black","is_ca":true},{"name":"Anne Joutel","is_ca":false},{"name":"Connie Marras","is_ca":true},{"name":"Ekaterina Rogaeva","is_ca":true},{"name":"Robert A. Hegele","is_ca":true},{"name":"Anthony E. Lang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006988260953109938,"gpt":0.1948034308509143,"spread":0.1878151698978044,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005217767,0.0002872383,0.0001872898,0.0005925236,0.0004908546,0.0004384182,0.0003397002,0.0002840496,0.002600583],"category_scores_gemma":[0.00225327,0.0001031708,0.0002779247,0.0009051498,0.0005142498,0.0001975552,0.0003461089,0.0002598513,0.0001526863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007859022,"about_ca_system_score_gemma":0.0008092792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.07496302,"about_ca_topic_score_gemma":0.1080298,"domain_scores_codex":[0.9997819,0.00004205107,0.00002424618,0.00006619569,0.00006054494,0.00002508631],"domain_scores_gemma":[0.998973,0.0002991032,0.0004903625,0.00006569417,0.00008085455,0.00009094163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001359927,0.000007813117,0.9943417,0.00001666867,0.0001021376,0.0001891216,0.0001034049,0.0001450508,0.000950938,0.00006413422,0.0001277192,0.003815423],"study_design_scores_gemma":[0.000008193579,0.00002386873,0.9978922,0.00001187186,0.00005620127,0.0005748129,0.00006602938,0.0006142211,0.0002485607,0.0002535151,0.0002473094,0.000003243055],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974524,0.0004041934,0.0004376456,0.0001185412,0.000003000225,0.000009920538,0.0006693656,0.00000967601,0.0008952205],"genre_scores_gemma":[0.9991627,0.00009016012,0.0002497729,0.00001673143,0.000003777844,0.000004531174,0.0003149269,0.000002638092,0.000154725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07496302,"threshold_uncertainty_score":0.1490534,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}