{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":1211,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":1211,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"dc61c5b95bed","filters":{"topic":"Developmental Biology and Gene Regulation"}},"results":[{"id":"W2157930949","doi":"10.1038/nature05571","title":"Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis","year":2007,"lang":"en","type":"article","venue":"Nature","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1763,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Notch signaling pathway; Sprouting angiogenesis; Cell biology; Angiogenesis; Biology; Sprouting; Endothelial stem cell; Signalling; Chemistry; Neovascularization; Signal transduction; Cancer research; Genetics; In vitro; Botany","authors":[{"name":"Mats Hellström","is_ca":false},{"name":"Li‐Kun Phng","is_ca":false},{"name":"Jennifer J. Hofmann","is_ca":false},{"name":"Elisabet Wallgard","is_ca":false},{"name":"Leigh Coultas","is_ca":true},{"name":"Per Henrik Lindblom","is_ca":false},{"name":"Jackelyn A. Alva","is_ca":false},{"name":"Ann-Katrin Nilsson","is_ca":false},{"name":"Linda Karlsson","is_ca":false},{"name":"Nicholas Gaiano","is_ca":false},{"name":"Keejung Yoon","is_ca":false},{"name":"Janet Rossant","is_ca":true},{"name":"M. Luisa Iruela‐Arispe","is_ca":false},{"name":"Mattias Kalén","is_ca":false},{"name":"Holger Gerhardt","is_ca":false},{"name":"Christer Betsholtz","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004404798550353197,"gpt":0.2297969362330513,"spread":0.2253921376826981,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003080692,0.0002657337,0.0003351389,0.0004662335,0.0004330848,0.0009674476,0.0005149142,0.0004540215,0.001195116],"category_scores_gemma":[0.0003313143,0.0003821401,0.0002762279,0.0001864626,0.0003121155,0.000568986,0.0007622187,0.00122162,0.0007560059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001579858,"about_ca_system_score_gemma":0.0003776356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001296583,"about_ca_topic_score_gemma":0.002341464,"domain_scores_codex":[0.9996252,0.00006237622,0.00002393939,0.00005554447,0.00009156599,0.0001414402],"domain_scores_gemma":[0.9996234,0.00004112156,0.00009081332,0.00002823781,0.00007011543,0.000146373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002203288,0.00001098567,0.0006622729,0.00003346727,0.000004653665,0.0001414357,0.00003270148,0.0001648206,0.9960192,0.0007300883,0.0001855121,0.00179447],"study_design_scores_gemma":[0.00003066121,0.00008049666,0.02732795,0.00001643582,0.00001695237,0.0002713355,0.0001578604,0.002751452,0.9631693,0.0004617862,0.005705416,0.00001041877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800336,0.004432026,0.007711082,0.0003483825,0.00006669608,0.00003676899,0.000424499,0.0001913916,0.006755575],"genre_scores_gemma":[0.9899832,0.0007846096,0.002095657,0.0001019694,0.00002538874,0.00003221989,0.0003912769,0.00006192338,0.006523742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001579858,"threshold_uncertainty_score":0.01146269,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1963742875","doi":"10.1002/gene.10092","title":"Expression of Cre recombinase in the developing mouse limb bud driven by a <i>Prxl</i> enhancer","year":2002,"lang":"en","type":"article","venue":"genesis","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1039,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Sunnybrook Health Science Centre; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; University of Alabama","keywords":"Limb bud; Cre recombinase; Biology; Mesenchyme; Enhancer; Transgene; Limb development; Genetically modified mouse; Reporter gene; Cell biology; Molecular biology; Gene expression; Genetics; Gene; Mesenchymal stem cell","authors":[{"name":"Malcolm Logan","is_ca":false},{"name":"James F. Martin","is_ca":false},{"name":"András Nagy","is_ca":true},{"name":"Corrinne G. Lobe","is_ca":true},{"name":"Eric N. Olson","is_ca":false},{"name":"Clifford J. Tabin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01100798310570987,"gpt":0.2256621303805343,"spread":0.2146541472748244,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038614,0.0002970429,0.0002398926,0.000294594,0.0002115622,0.000391183,0.0005036519,0.0003921097,0.002044138],"category_scores_gemma":[0.0001751293,0.0004255652,0.0002754663,0.000179841,0.0003242813,0.0003467336,0.0002813613,0.0008330711,0.001702218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002709022,"about_ca_system_score_gemma":0.0002559698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004773942,"about_ca_topic_score_gemma":0.0005067301,"domain_scores_codex":[0.9997638,0.00002677567,0.00002863278,0.0000641431,0.00007320623,0.00004352724],"domain_scores_gemma":[0.9998193,0.00003250944,0.00004975612,0.00003220174,0.00002022058,0.00004601899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001931755,0.00000687384,0.00003963695,0.00001837568,0.000001012448,0.00002894423,0.000009336572,0.00002942676,0.9987774,0.0001751934,0.00002610913,0.0008682018],"study_design_scores_gemma":[0.00002713774,0.0001190657,0.0009026172,0.000009904234,0.00001020381,0.0003780889,0.00001022538,0.0003709505,0.9912065,0.00004527413,0.006917245,0.000002831409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8545334,0.004405278,0.1236196,0.0004786355,0.0001783563,0.0004239569,0.00209116,0.001656028,0.01261355],"genre_scores_gemma":[0.8697742,0.003721594,0.09766352,0.0001662498,0.00005845315,0.0002774626,0.002640192,0.0003745833,0.0253239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002044138,"threshold_uncertainty_score":0.006838322,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2062711358","doi":"10.1158/0008-5472.can-05-1069","title":"High-level Coexpression of JAG1 and NOTCH1 Is Observed in Human Breast Cancer and Is Associated with Poor Overall Survival","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":781,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"","keywords":"JAG1; Tissue microarray; Breast cancer; Medicine; Notch signaling pathway; Internal medicine; Cancer; Survival rate; Oncology; Survival analysis; Receptor; Cancer research; Pathology","authors":[{"name":"Michael Reedijk","is_ca":true},{"name":"Silvia Odorcic","is_ca":true},{"name":"Lynn Chang","is_ca":true},{"name":"Hui Zhang","is_ca":true},{"name":"Naomi Miller","is_ca":false},{"name":"David R. McCready","is_ca":false},{"name":"Gina Lockwood","is_ca":true},{"name":"Sean E. Egan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06266336039111539,"gpt":0.3559054139079137,"spread":0.2932420535167983,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002823281,0.0001769309,0.0004162405,0.0008274458,0.0002661798,0.0004750349,0.0001217075,0.0002844887,0.0006968025],"category_scores_gemma":[0.0004010975,0.0002228932,0.000153921,0.0007162081,0.0003435192,0.0001512537,0.0004003549,0.0003837102,0.0001902105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002216115,"about_ca_system_score_gemma":0.0001792447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004596182,"about_ca_topic_score_gemma":0.000639469,"domain_scores_codex":[0.9997484,0.00003800668,0.000024671,0.0000605778,0.00007001054,0.00005837912],"domain_scores_gemma":[0.9995166,0.00007379797,0.0002243948,0.00004386259,0.00002948395,0.0001118963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001248832,0.00009601529,0.5069944,0.00007459096,0.000180005,0.0009275969,0.0001591026,0.0002287676,0.4828142,0.0001096891,0.0002479659,0.006918878],"study_design_scores_gemma":[0.00001763406,0.0002427525,0.9748567,0.000006064002,0.00007234942,0.003497476,0.0001481433,0.0002138075,0.01996657,0.0001078091,0.0008626489,0.000007992134],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988433,0.0006891856,0.0001280241,0.00002498384,0.000002260998,0.000003086225,0.00007220179,0.00000952657,0.0002272698],"genre_scores_gemma":[0.9991041,0.000323718,0.0001714149,0.00002831234,0.000006847426,0.00000577918,0.0001860107,0.000002791204,0.0001710442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008274458,"threshold_uncertainty_score":0.002331078,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044484847","doi":"10.1016/s0092-8674(00)80860-0","title":"Transient Notch Activation Initiates an Irreversible Switch from Neurogenesis to Gliogenesis by Neural Crest Stem Cells","year":2000,"lang":"en","type":"article","venue":"Cell","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":720,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Gliogenesis; Neuroblast; Neurogenesis; Biology; Neural stem cell; Neural crest; Notch signaling pathway; Stem cell; Cell biology; Neuroscience; Neuroepithelial cell; Subventricular zone; Multipotent Stem Cell; Anatomy; Progenitor cell; Signal transduction","authors":[{"name":"Sean J. Morrison","is_ca":false},{"name":"Sharon E. Perez","is_ca":false},{"name":"Qiao Zhou","is_ca":false},{"name":"Joseph M. Verdi","is_ca":true},{"name":"Carol Hicks","is_ca":false},{"name":"Gerry Weinmaster","is_ca":false},{"name":"David J. Anderson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008901608636467048,"gpt":0.2110567445178149,"spread":0.2021551358813478,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001769573,0.0003271904,0.0004658601,0.0003209723,0.0002021048,0.0008624019,0.0003656015,0.0003040837,0.002106899],"category_scores_gemma":[0.0002361772,0.0003793377,0.0003273015,0.000246913,0.0003442843,0.0003830644,0.0005410265,0.0009870125,0.0008772596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005362577,"about_ca_system_score_gemma":0.0003611455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005319884,"about_ca_topic_score_gemma":0.001313387,"domain_scores_codex":[0.9997175,0.00002129776,0.00002495704,0.00005969733,0.00008542754,0.00009109772],"domain_scores_gemma":[0.9997638,0.00006835972,0.00003688248,0.00004779064,0.00001974736,0.00006340101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001489571,0.00001079926,0.0001720895,0.00002554581,0.000005619945,0.00009598122,0.00001475774,0.00003352731,0.9975616,0.0004699302,0.00004944517,0.001411721],"study_design_scores_gemma":[0.00001195499,0.00005367299,0.003206062,0.000004276241,0.000009488594,0.0001224546,0.00002152082,0.0002462862,0.994742,0.00008472244,0.001493784,0.000003669955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854225,0.002734748,0.006156159,0.0001007952,0.0001195515,0.00004442421,0.0005497014,0.0003416888,0.004530443],"genre_scores_gemma":[0.9900299,0.0007622751,0.001664978,0.00007587998,0.00003318285,0.00004856846,0.0006992125,0.0001034408,0.006582572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002106899,"threshold_uncertainty_score":0.007048309,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124109473","doi":"10.1101/gad.14.1.67","title":"A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons","year":2000,"lang":"en","type":"article","venue":"Genes & Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":624,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Institut National de la Santé et de la Recherche Médicale; Centre National de la Recherche Scientifique; Association pour la Recherche sur le Cancer","keywords":"Biology; Cerebrum; Ganglionic eminence; Forebrain; Neurogenesis; Neuroscience; Ectopic expression; Mutant; Cell biology; Gene; Anatomy; Genetics; Central nervous system","authors":[{"name":"Carol Fode","is_ca":false},{"name":"Qiufu Ma","is_ca":false},{"name":"Simona Casarosa","is_ca":false},{"name":"Siew-Lan Ang","is_ca":false},{"name":"David J. Anderson","is_ca":false},{"name":"François Guillemot","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01116497481747061,"gpt":0.2553912290387884,"spread":0.2442262542213178,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009653437,0.0003087946,0.0001220331,0.0001994163,0.000195969,0.0003470605,0.000245395,0.0002522719,0.000638473],"category_scores_gemma":[0.00008036411,0.0001325732,0.0001200176,0.00007756746,0.0004372502,0.000336106,0.0003459931,0.0002128017,0.0002455747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004718695,"about_ca_system_score_gemma":0.0003518315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007712271,"about_ca_topic_score_gemma":0.001343784,"domain_scores_codex":[0.9999018,0.00001087531,0.000005850298,0.00003485863,0.00003118447,0.00001546431],"domain_scores_gemma":[0.9999356,0.000008709336,0.00001728402,0.000007710776,0.000008283903,0.00002239518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004092703,0.000007429152,0.0004872872,0.0000227534,0.000001623079,0.0001524608,0.00001429539,0.00008170895,0.9966314,0.0007336787,0.00002173775,0.001804685],"study_design_scores_gemma":[0.00002201907,0.000167039,0.03480812,0.00001572804,0.00001457825,0.001309996,0.00009255252,0.001614808,0.9522312,0.0004989071,0.009213611,0.00001157797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782576,0.007038377,0.006925264,0.0002202224,0.00004540867,0.0000276687,0.0002453117,0.00006836479,0.007171857],"genre_scores_gemma":[0.9846051,0.002149655,0.005294035,0.00006559727,0.00001770654,0.00002695258,0.000262359,0.00001418114,0.007564456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007712271,"threshold_uncertainty_score":0.003423691,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1657005131","doi":"10.1038/35001072","title":"The organizer factors Chordin and Noggin are required for mouse forebrain development","year":2000,"lang":"en","type":"article","venue":"Nature","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":530,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Whitehead Foundation","keywords":"Chordin; Noggin; Endoderm; Ectoderm; Biology; Forebrain; Gastrulation; Cell biology; Anatomy; Bone morphogenetic protein; Mesoderm; Hedgehog; Embryonic stem cell; Embryo; Genetics; Endocrinology; Embryogenesis; Central nervous system; Gene; Signal transduction","authors":[{"name":"Daniel Bachiller","is_ca":false},{"name":"John Klingensmith","is_ca":false},{"name":"Caroline Kemp","is_ca":false},{"name":"José António Belo","is_ca":false},{"name":"Ryan M. Anderson","is_ca":false},{"name":"S. Randolph May","is_ca":false},{"name":"Jill A. McMahon","is_ca":false},{"name":"Andrew P. McMahon","is_ca":false},{"name":"Richard M. Harland","is_ca":false},{"name":"Janet Rossant","is_ca":true},{"name":"Edward M. De Robertis","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005128563606628236,"gpt":0.2291942925781225,"spread":0.2240657289714942,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001603315,0.0005049745,0.0002913623,0.0005385767,0.0003696109,0.0006978865,0.0004386989,0.0003690475,0.0006536788],"category_scores_gemma":[0.0002813527,0.000543764,0.000219518,0.0001792485,0.0005439381,0.0003333932,0.0004883796,0.0007730011,0.0004311413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006375922,"about_ca_system_score_gemma":0.0004310072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001378887,"about_ca_topic_score_gemma":0.004178585,"domain_scores_codex":[0.9997495,0.00001577878,0.00001724266,0.00004088546,0.0001177439,0.00005887438],"domain_scores_gemma":[0.9995416,0.00003660544,0.0001982101,0.00004072633,0.00003842273,0.0001444936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007167795,0.000002700694,0.0003734077,0.00001094098,0.00000349813,0.0001198538,0.000007317323,0.00006290041,0.998123,0.0003635974,0.00002868656,0.0008325138],"study_design_scores_gemma":[0.00002035408,0.00005756608,0.02150002,0.00000609248,0.0000304439,0.0008014924,0.00004943201,0.0006789093,0.9708985,0.0003864573,0.00556198,0.000008736659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840592,0.003010476,0.00789778,0.0001627359,0.00005932391,0.00001641939,0.0005472307,0.000368485,0.003878346],"genre_scores_gemma":[0.9875801,0.001109026,0.004610781,0.00006349086,0.00001691133,0.00002023697,0.0007399024,0.0001435414,0.005715955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001378887,"threshold_uncertainty_score":0.004626095,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1507923114","doi":"10.1038/35017617","title":"Initiation of neural induction by FGF signalling before gastrulation","year":2000,"lang":"en","type":"article","venue":"Nature","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":525,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Merck Canada","keywords":"Gastrulation; Neural development; Fibroblast growth factor; Embryonic Induction; Biology; Embryo; Neural plate; Cell biology; Embryogenesis; Epiblast; Neural tube; Neuroscience; Gene; Mesoderm; Genetics; Embryonic stem cell","authors":[{"name":"Andrea Streit","is_ca":false},{"name":"Alyson J. Berliner","is_ca":false},{"name":"Costis Papanayotou","is_ca":false},{"name":"Andres Sirulnik","is_ca":false},{"name":"Claudio D. Stern","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003714388312304319,"gpt":0.2278501272758331,"spread":0.2241357389635288,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002788281,0.0003489462,0.00045156,0.0004539034,0.0003735215,0.0007550533,0.0002754429,0.0004720094,0.003417439],"category_scores_gemma":[0.0006491764,0.0005915242,0.0004050182,0.0001746974,0.0002870719,0.0006211047,0.0005979591,0.001056457,0.001613695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008369105,"about_ca_system_score_gemma":0.0004676883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001830072,"about_ca_topic_score_gemma":0.00358801,"domain_scores_codex":[0.999728,0.00003148601,0.00001648294,0.00004460693,0.00007386097,0.0001055673],"domain_scores_gemma":[0.9995535,0.0001643121,0.00004216899,0.00005638355,0.00008235764,0.0001012214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004254013,0.00001158779,0.0004542476,0.000073119,0.000004166825,0.0001251616,0.00003384558,0.00009280691,0.9937919,0.001413834,0.000254464,0.003319443],"study_design_scores_gemma":[0.00002338563,0.0001037029,0.01739675,0.00002711467,0.000008871124,0.0001368508,0.00004655386,0.0006192606,0.9726654,0.0003655774,0.008597833,0.000008553232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9248608,0.0131347,0.02480808,0.0007602141,0.000532132,0.0001506367,0.00130935,0.001210945,0.03323314],"genre_scores_gemma":[0.9777882,0.001515706,0.003556028,0.0002146642,0.00008582791,0.00007591461,0.001172962,0.0001593172,0.01543147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003417439,"threshold_uncertainty_score":0.01143247,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2135740919","doi":"10.1101/gr.073676.107","title":"The amphioxus genome illuminates vertebrate origins and cephalochordate biology","year":2008,"lang":"en","type":"article","venue":"Genome Research","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":511,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Victoria; University of Toronto; Sunnybrook Health Science Centre","funders":"Biotechnology and Biological Sciences Research Council; Centre National de la Recherche Scientifique; Ministero dell’Istruzione, dell’Università e della Ricerca; National Institute of Allergy and Infectious Diseases; European Commission; Wellcome Trust; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; National Institutes of Health; National Science Foundation","keywords":"Chordate; Biology; Hox gene; Genome; Homeobox; Vertebrate; Genetics; Evolutionary biology; Gene; Enhancer; Gene duplication; Transcription factor","authors":[{"name":"Linda Z. Holland","is_ca":false},{"name":"Ricard Albalat","is_ca":false},{"name":"Kaoru Azumi","is_ca":false},{"name":"Èlia Benito‐Gutiérrez","is_ca":false},{"name":"Matthew J. Blow","is_ca":false},{"name":"Marianne Bronner‐Fraser","is_ca":false},{"name":"Frédéric Brunet","is_ca":false},{"name":"Thomas Butts","is_ca":false},{"name":"Simona Candiani","is_ca":false},{"name":"Larry J. Dishaw","is_ca":false},{"name":"David Ferrier","is_ca":false},{"name":"Jordi García‐Fernàndez","is_ca":false},{"name":"Jeremy J. Gibson‐Brown","is_ca":false},{"name":"Carmela Gissi","is_ca":false},{"name":"Adam Godzik","is_ca":false},{"name":"Finn Hallböök","is_ca":false},{"name":"Dan Hirose","is_ca":false},{"name":"Kazuyoshi Hosomichi","is_ca":false},{"name":"Tetsuro Ikuta","is_ca":false},{"name":"Hidetoshi Inoko","is_ca":false},{"name":"Masanori Kasahara","is_ca":false},{"name":"Jun Kasamatsu","is_ca":false},{"name":"Takeshi Kawashima","is_ca":false},{"name":"Ayuko Kimura","is_ca":false},{"name":"Masaaki Kobayashi","is_ca":false},{"name":"Zbyněk Kozmík","is_ca":false},{"name":"Kaoru Kubokawa","is_ca":false},{"name":"Vincent Laudet","is_ca":false},{"name":"Gary W. Litman","is_ca":false},{"name":"Alice C. McHardy","is_ca":false},{"name":"Daniel Meulemans","is_ca":false},{"name":"Masaru Nonaka","is_ca":false},{"name":"Robert P. Olinski","is_ca":false},{"name":"Zeev Pancer","is_ca":false},{"name":"L Pennacchio","is_ca":false},{"name":"Mario Pestarino","is_ca":false},{"name":"Jonathan P. Rast","is_ca":true},{"name":"Isidore Rigoutsos","is_ca":false},{"name":"Marc Robinson‐Rechavi","is_ca":false},{"name":"Graeme J. Roch","is_ca":true},{"name":"Hidetoshi Saiga","is_ca":false},{"name":"Yasunori Sasakura","is_ca":false},{"name":"Masanobu Satake","is_ca":false},{"name":"Yutaka Satou","is_ca":false},{"name":"Michael Schubert","is_ca":false},{"name":"Nancy M. Sherwood","is_ca":true},{"name":"Takashi Shiina","is_ca":false},{"name":"Naohito Takatori","is_ca":false},{"name":"Javier A. Tello","is_ca":true},{"name":"Pavel Vopálenský","is_ca":false},{"name":"Shuichi Wada","is_ca":false},{"name":"Anlong Xu","is_ca":false},{"name":"Yuzhen Ye","is_ca":false},{"name":"Keita Yoshida","is_ca":false},{"name":"Fumiko Yoshizaki","is_ca":false},{"name":"J-R Yu","is_ca":false},{"name":"Qing Zhang","is_ca":false},{"name":"Christian M. Zmasek","is_ca":false},{"name":"Pieter J. de Jong","is_ca":false},{"name":"Kazutoyo Osoegawa","is_ca":false},{"name":"Nicholas H. Putnam","is_ca":false},{"name":"Daniel S. Rokhsar","is_ca":false},{"name":"Noriyuki Satoh","is_ca":false},{"name":"Peter W. H. Holland","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03640453326177989,"gpt":0.3225527918107469,"spread":0.286148258548967,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002705434,0.0004203073,0.0003017529,0.001146482,0.0004449488,0.000551976,0.0001997122,0.0003574094,0.002640131],"category_scores_gemma":[0.0003778477,0.0002070803,0.0003824208,0.001285824,0.000148129,0.0004842966,0.0005810764,0.0005989076,0.0005942564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002358858,"about_ca_system_score_gemma":0.0004010809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001806367,"about_ca_topic_score_gemma":0.003207085,"domain_scores_codex":[0.9998831,0.00001334211,0.000007084226,0.00005524121,0.0000268827,0.00001435694],"domain_scores_gemma":[0.9997947,0.00004560991,0.00003995413,0.00002474287,0.00005378339,0.00004135266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004450923,0.00007605785,0.07488003,0.002428191,0.0002888484,0.000906712,0.001096961,0.001159135,0.6918513,0.006348069,0.02180318,0.1987164],"study_design_scores_gemma":[0.00008804889,0.0001906928,0.5967587,0.0005312288,0.0004881161,0.001391314,0.0006005973,0.002866689,0.04432055,0.004458532,0.3482391,0.0000664247],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.777664,0.04789598,0.02037837,0.002541475,0.0005437194,0.0001032213,0.116546,0.001565302,0.03276198],"genre_scores_gemma":[0.8082286,0.02242574,0.04174753,0.001440457,0.0004528865,0.0001837933,0.1138029,0.0004122525,0.01130586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002640131,"threshold_uncertainty_score":0.008832097,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1573866353","doi":"10.1038/90081","title":"Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail","year":2001,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":499,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta; McGill University","funders":"National Cancer Institute","keywords":"Neural tube; Biology; Dishevelled; Frizzled; Convergent extension; Neuroectoderm; Genetics; Genetic screen; Neural plate; Mutant; Axon guidance; Gene; Cell biology; Embryo; Embryogenesis; Wnt signaling pathway; Embryonic stem cell; Mesoderm","authors":[{"name":"Zoha Kibar","is_ca":true},{"name":"Kyle Vogan","is_ca":false},{"name":"Normand Groulx","is_ca":true},{"name":"Monica J. Justice","is_ca":false},{"name":"D. Alan Underhill","is_ca":true},{"name":"Philippe Gros","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008209169283375431,"gpt":0.2491343677827318,"spread":0.2409251984993564,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001469229,0.000965748,0.0004021892,0.001293226,0.0005604516,0.0006927176,0.001042551,0.001109962,0.003072582],"category_scores_gemma":[0.0003373679,0.0005374338,0.0004029069,0.0004665002,0.0009947025,0.0004026668,0.0007799214,0.001003703,0.001773792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005264804,"about_ca_system_score_gemma":0.0003540303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00138514,"about_ca_topic_score_gemma":0.002001644,"domain_scores_codex":[0.9996561,0.00003493402,0.00003854344,0.00007566017,0.0001350525,0.00005986297],"domain_scores_gemma":[0.9991727,0.00009004563,0.0003913504,0.00005333333,0.00004642247,0.0002459553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001208905,0.00001024384,0.0002112197,0.00002265692,0.00000764175,0.000485663,0.00001765516,0.00007489298,0.9983566,0.0001826417,0.00003511459,0.0004747679],"study_design_scores_gemma":[0.00005761669,0.0001108078,0.02010241,0.00001706399,0.00007230246,0.004187272,0.0001118488,0.001460617,0.9700114,0.0002896863,0.003553775,0.00002519116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910327,0.001018612,0.004609665,0.000148193,0.00007452579,0.00002357849,0.001018743,0.0004032735,0.001670624],"genre_scores_gemma":[0.9918829,0.0003622127,0.001513026,0.00007330758,0.0000155007,0.00003661244,0.0009880388,0.0002157823,0.004912607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003072582,"threshold_uncertainty_score":0.01027882,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2001957066","doi":"10.1182/blood-2005-08-3329","title":"Recent insights into the role of Notch signaling in tumorigenesis","year":2005,"lang":"en","type":"review","venue":"Blood","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":494,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Notch signaling pathway; Carcinogenesis; Hes3 signaling axis; Biology; Cell biology; Signal transduction; Angiogenesis; Cancer research; Notch proteins; Transmembrane protein; Cell fate determination; Receptor; Genetics; Cancer; Transcription factor","authors":[{"name":"Kevin G. Leong","is_ca":true},{"name":"Aly Karsan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01204633314042057,"gpt":0.2670608608485547,"spread":0.2550145277081342,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004271717,0.0005893054,0.0007102015,0.001260161,0.0002304349,0.0007885874,0.0005352104,0.0006306166,0.002174848],"category_scores_gemma":[0.0003691102,0.0002153402,0.0002253856,0.001673879,0.0003448504,0.001067697,0.0005516178,0.0009224087,0.001636137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006574779,"about_ca_system_score_gemma":0.0006516693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007477372,"about_ca_topic_score_gemma":0.001316677,"domain_scores_codex":[0.999887,0.00001672627,0.0000189338,0.00002193228,0.000044125,0.00001122882],"domain_scores_gemma":[0.9998637,0.00004227846,0.00001927025,0.000006973821,0.00004557776,0.00002217096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001221245,0.0000456441,0.0002449965,0.009104941,0.00008101577,0.0006843717,0.0001270217,0.0008412724,0.01031675,0.006784559,0.0208376,0.9508097],"study_design_scores_gemma":[0.00001111788,0.00005660342,0.0008697229,0.001078699,0.00007227663,0.001713064,0.00007513904,0.0001229989,0.001603848,0.003156858,0.9912257,0.00001398718],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003218118,0.9975886,0.0002813958,0.0002563382,0.0001783025,0.000001928597,0.00001099914,0.000007735745,0.001352829],"genre_scores_gemma":[0.001098357,0.997485,0.0002578306,0.0001427944,0.0001634681,0.000002292097,0.00001521979,9.327314e-7,0.0008340142],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002174848,"threshold_uncertainty_score":0.007275641,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1976021347","doi":"10.1038/sj.onc.1210760","title":"Hox genes in hematopoiesis and leukemogenesis","year":2007,"lang":"en","type":"review","venue":"Oncogene","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":484,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Hox gene; Biology; Haematopoiesis; Stem cell; Gene; Fusion gene; Genetics; Cancer research; Gene expression","authors":[{"name":"Bob Argiropoulos","is_ca":true},{"name":"R. Keith Humphries","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03899869364219685,"gpt":0.3467502869512398,"spread":0.3077515933090429,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005781639,0.001082226,0.001267325,0.001207128,0.0004030039,0.001000289,0.001368779,0.001077252,0.003218143],"category_scores_gemma":[0.0004620069,0.0003754384,0.0002792173,0.002659844,0.001061357,0.001168733,0.0007342222,0.002203152,0.002409189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008493767,"about_ca_system_score_gemma":0.001073029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001137302,"about_ca_topic_score_gemma":0.002573813,"domain_scores_codex":[0.9998415,0.00001828178,0.00001756535,0.00002691986,0.00007537214,0.00002045174],"domain_scores_gemma":[0.9998459,0.00006046699,0.00001780538,0.000008055939,0.00004678136,0.00002112957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001057585,0.00006330866,0.0002000153,0.004788995,0.00005006609,0.0003483058,0.00006703507,0.0006101044,0.005419973,0.01022133,0.06629054,0.9118345],"study_design_scores_gemma":[0.00001438982,0.00001808618,0.0003876061,0.0004221882,0.00003583162,0.0006829594,0.00003478794,0.00006474299,0.0007818961,0.001837925,0.9957123,0.000007478866],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002558998,0.9941289,0.001018061,0.0004989592,0.0009651466,0.000009171247,0.00003223969,0.00002345543,0.003068223],"genre_scores_gemma":[0.001501921,0.9925098,0.001050306,0.0003229136,0.0006146948,0.0000173961,0.00006427905,0.000005259206,0.003913332],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003218143,"threshold_uncertainty_score":0.01076579,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1974096298","doi":"10.1074/jbc.m302827200","title":"Mammalian Numb Proteins Promote Notch1 Receptor Ubiquitination and Degradation of the Notch1 Intracellular Domain","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":459,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"NUMB; HES1; Notch signaling pathway; Cell biology; Ubiquitin; Ubiquitin ligase; Biology; Cell fate determination; Signal transduction; Intracellular; Transcription factor; Biochemistry; Gene","authors":[{"name":"Melanie A. McGill","is_ca":true},{"name":"C. Jane McGlade","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008899818116244587,"gpt":0.2175603644696943,"spread":0.2086605463534497,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001549144,0.0002716304,0.0001921223,0.0001753934,0.0002311247,0.0003514666,0.0001001859,0.0001514684,0.001587966],"category_scores_gemma":[0.0001741909,0.0001663375,0.000161645,0.000105081,0.0002059104,0.0002219687,0.0004588311,0.0002354777,0.0007243328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004294145,"about_ca_system_score_gemma":0.0001418338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002329197,"about_ca_topic_score_gemma":0.0006719499,"domain_scores_codex":[0.9998424,0.00003244344,0.00001206098,0.00002815484,0.00005358582,0.0000313377],"domain_scores_gemma":[0.9998955,0.00001239093,0.00003522185,0.00001314945,0.000009172191,0.00003465955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006676983,0.000009510595,0.0004732817,0.0000383915,0.000009003033,0.00008757874,0.00001556603,0.00004333974,0.9971979,0.0002591521,0.00003999733,0.001759418],"study_design_scores_gemma":[0.0000112618,0.0000839747,0.007912722,0.00001010424,0.000008863294,0.0006311827,0.00003736993,0.0008663069,0.9860268,0.0001567232,0.004251936,0.000002759281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900545,0.004000667,0.002711168,0.00007655327,0.00001685911,0.000009454171,0.0001220157,0.00005952311,0.002949335],"genre_scores_gemma":[0.9931753,0.0009634771,0.001589465,0.00002744401,0.000005803172,0.00001048101,0.0002413856,0.00001341929,0.003973254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001587966,"threshold_uncertainty_score":0.005312264,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1971221092","doi":"10.1038/nature02796","title":"Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation","year":2004,"lang":"en","type":"article","venue":"Nature","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":415,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"University of British Columbia","keywords":"Gastrulation; Zebrafish; Cell biology; Dishevelled; Cell division; Wnt signaling pathway; Biology; Asymmetric cell division; Cell polarity; Convergent extension; Frizzled; Mitosis; Xenopus; Caenorhabditis elegans; Cell fate determination; Cell; Genetics; Signal transduction; Embryo; Embryogenesis","authors":[{"name":"Ying Gong","is_ca":false},{"name":"Chunhui Mo","is_ca":false},{"name":"Scott E. Fraser","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.002682233579789708,"gpt":0.2128086131309181,"spread":0.2101263795511285,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001725673,0.0004381404,0.0004249397,0.0004499157,0.0005419496,0.001129899,0.0005141062,0.0005990712,0.002030453],"category_scores_gemma":[0.0003734922,0.0007886393,0.0002317447,0.000224273,0.0007911896,0.0008606956,0.0007575694,0.001145561,0.0009642853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002074533,"about_ca_system_score_gemma":0.0007540862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006749991,"about_ca_topic_score_gemma":0.02086689,"domain_scores_codex":[0.9997342,0.00001623596,0.000008676315,0.00004859544,0.00008749473,0.0001047403],"domain_scores_gemma":[0.9997032,0.00003122976,0.00009213324,0.00002196609,0.00005427594,0.0000972339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001272253,0.000003088562,0.000428116,0.0000181942,0.000002138654,0.00005881388,0.00003660393,0.0001038221,0.9972631,0.0007340362,0.00009151224,0.001133365],"study_design_scores_gemma":[0.00006782997,0.0001218177,0.08611777,0.00002805377,0.00002879545,0.0001696078,0.0002189161,0.002845597,0.9037889,0.0005842941,0.005997654,0.00003070467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827488,0.002570944,0.004681007,0.0003080196,0.00008375471,0.00001801589,0.0003703454,0.0001652136,0.009053902],"genre_scores_gemma":[0.9869226,0.0006721429,0.001170549,0.000125674,0.00002143786,0.00002397467,0.0002841725,0.0001131109,0.01066643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006749991,"threshold_uncertainty_score":0.0150519,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2035422545","doi":"10.1242/dev.00669","title":"Spatial and temporal patterns of ERK signaling during mouse embryogenesis","year":2003,"lang":"en","type":"article","venue":"Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":390,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; MAPK/ERK pathway; Cell biology; Fibroblast growth factor; Receptor tyrosine kinase; Signal transduction; FGF8; Fibroblast growth factor receptor; Receptor; Genetics","authors":[{"name":"Laura Corson","is_ca":true},{"name":"Yojiro Yamanaka","is_ca":true},{"name":"Ka‐Man Venus Lai","is_ca":true},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006842307217697827,"gpt":0.2067283904297293,"spread":0.1998860832120315,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001861015,0.0002438196,0.0001655875,0.0008837294,0.0001755982,0.00036347,0.0002148081,0.000271463,0.001244853],"category_scores_gemma":[0.0001627438,0.0002944865,0.00022406,0.0002862574,0.0002425076,0.0002582963,0.0002411088,0.0006946913,0.0006442432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000326414,"about_ca_system_score_gemma":0.000133653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004657985,"about_ca_topic_score_gemma":0.0008013013,"domain_scores_codex":[0.9997659,0.00002095161,0.0000230315,0.00007679679,0.00006334737,0.00004989472],"domain_scores_gemma":[0.9998475,0.00002347894,0.00004970482,0.00001495381,0.00002393152,0.00004039918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002191555,0.00001747336,0.0008323861,0.00003082469,0.000004428039,0.00009137566,0.00004965706,0.00006764886,0.9958858,0.0001951965,0.00004799338,0.002558136],"study_design_scores_gemma":[0.0000279978,0.0002956078,0.05122579,0.00002966608,0.00002597386,0.0008322273,0.00006363242,0.0009768772,0.9419972,0.0002536445,0.004253056,0.00001829865],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797713,0.004952234,0.008257058,0.00009135372,0.00002126544,0.00006579817,0.001597867,0.0002587614,0.004984384],"genre_scores_gemma":[0.9826096,0.001930945,0.006611092,0.00009253731,0.00001378131,0.0001464121,0.001655935,0.00008534754,0.006854387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001244853,"threshold_uncertainty_score":0.004164398,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2162184748","doi":"10.1158/0008-5472.can-04-1446","title":"<b> <i>Notch1</i> </b> and <b> <i>Notch2</i> </b> Have Opposite Effects on Embryonal Brain Tumor Growth","year":2004,"lang":"en","type":"article","venue":"Cancer Research","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":383,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"HES1; Biology; Notch signaling pathway; Carcinogenesis; Medulloblastoma; Cancer research; Progenitor cell; Cell growth; Oncogene; Cell; Signal transduction; Cell cycle; Cell biology; Gene; Stem cell; Genetics","authors":[{"name":"Xing Fan","is_ca":false},{"name":"Irina Mikolaenko","is_ca":false},{"name":"Ihab O. Elhassan","is_ca":false},{"name":"XingZhi Ni","is_ca":false},{"name":"Yunyue Wang","is_ca":true},{"name":"Douglas W. Ball","is_ca":true},{"name":"Daniel J. Brat","is_ca":false},{"name":"Arie Perry","is_ca":false},{"name":"Charles G. Eberhart","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01676653878781147,"gpt":0.3286821687583751,"spread":0.3119156299705636,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119395,0.0002810999,0.0001625464,0.0002381928,0.0001008148,0.0002865684,0.0001065936,0.0001536052,0.0009709695],"category_scores_gemma":[0.0001283176,0.0001264189,0.0001670894,0.0001012206,0.0001759364,0.000141566,0.0001445596,0.0003545626,0.0003381862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000200247,"about_ca_system_score_gemma":0.0001476263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005990455,"about_ca_topic_score_gemma":0.0006802742,"domain_scores_codex":[0.9998593,0.00001889111,0.00001803458,0.00003009557,0.00004709601,0.00002663232],"domain_scores_gemma":[0.9998633,0.00002619891,0.00003788781,0.00001829673,0.00001182958,0.00004249596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003926831,0.000004111763,0.00029247,0.000006816707,0.000003032885,0.00001724901,0.00000304835,0.00001815659,0.9991424,0.00004130086,0.000009711871,0.0004223942],"study_design_scores_gemma":[0.000008305219,0.0001783004,0.01243038,0.000003285428,0.00001646574,0.0005919323,0.00002766878,0.0005122962,0.9848995,0.00005200588,0.001276287,0.000003615877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954006,0.0007967089,0.001428085,0.00003340265,0.000009728516,0.000008584395,0.0002391059,0.0000410322,0.002042712],"genre_scores_gemma":[0.9947919,0.0006622325,0.00202761,0.0000459921,0.000004087204,0.00001798667,0.0005109498,0.00002326471,0.001916066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009709695,"threshold_uncertainty_score":0.003248155,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1947231608","doi":"10.1523/jneurosci.20-02-00709.2000","title":"A Highly Conserved Enhancer in the<i>Dlx5/Dlx6</i>Intergenic Region is the Site of Cross-Regulatory Interactions between<i>Dlx</i>Genes in the Embryonic Forebrain","year":2000,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":367,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Deutscher Akademischer Austauschdienst; March of Dimes Foundation","keywords":"DLX5; Zebrafish; Biology; Forebrain; Homeobox; Enhancer; Genetics; Gene; Homeotic gene; Gene expression; Neuroscience","authors":[{"name":"Ted Zerucha","is_ca":true},{"name":"Thorsten Stühmer","is_ca":false},{"name":"Gary Hatch","is_ca":true},{"name":"Byung K. Park","is_ca":true},{"name":"Qiaoming Long","is_ca":true},{"name":"Guoying Karen Yu","is_ca":false},{"name":"Adrianna Gambarotta","is_ca":true},{"name":"Joshua R. Schultz","is_ca":false},{"name":"John L.R. Rubenstein","is_ca":false},{"name":"Marc Ekker","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01989790505758063,"gpt":0.2966665563937543,"spread":0.2767686513361737,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001082832,0.0002947879,0.0002003461,0.0002243821,0.0002206333,0.0002146842,0.0002936658,0.0002753836,0.001564396],"category_scores_gemma":[0.0001511906,0.0002394473,0.0003758347,0.0001065537,0.0003288246,0.0001507705,0.0003940984,0.0007441672,0.0008658536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002507821,"about_ca_system_score_gemma":0.0001879886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002991097,"about_ca_topic_score_gemma":0.0006070377,"domain_scores_codex":[0.9998387,0.00001458879,0.000009568294,0.00006680883,0.00004384975,0.00002649927],"domain_scores_gemma":[0.9998493,0.00002320522,0.00005432375,0.00001639391,0.000009536301,0.00004715194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003365576,0.00001047998,0.0002121382,0.00001501526,0.000002189091,0.00004685576,0.00001221228,0.00002743994,0.9984797,0.0001520042,0.00001461224,0.0009937315],"study_design_scores_gemma":[0.00003914747,0.0002231029,0.03338273,0.00002852924,0.0000229673,0.001130782,0.00003390669,0.0007348125,0.9565534,0.000220329,0.00761999,0.0000103057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9730158,0.001144375,0.02148769,0.00009726297,0.0000486606,0.00005391319,0.0004437006,0.000312205,0.003396278],"genre_scores_gemma":[0.9787815,0.0002927504,0.01519694,0.0001199637,0.00001709583,0.00004490141,0.00136956,0.00005883201,0.004118305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001564396,"threshold_uncertainty_score":0.005233407,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2087274355","doi":"10.3389/fncel.2014.00293","title":"Motor neurons and the generation of spinal motor neuron diversity","year":2014,"lang":"en","type":"review","venue":"Frontiers in Cellular Neuroscience","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":357,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"European Bioinformatics Institute","keywords":"Neuroscience; Biology; Motor neuron; Nervous system; Anatomy; Spinal cord","authors":[{"name":"Nicolas Stifani","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02822995921665938,"gpt":0.2582317694007263,"spread":0.2300018101840669,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003333414,0.0002947862,0.0004951023,0.0007572442,0.0003524919,0.001027827,0.0006091711,0.001009077,0.001609316],"category_scores_gemma":[0.0003162584,0.0001538234,0.0003433676,0.0004558629,0.0008323416,0.001043419,0.0008195029,0.001044107,0.0006882193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007578983,"about_ca_system_score_gemma":0.0007843269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007465485,"about_ca_topic_score_gemma":0.001092049,"domain_scores_codex":[0.9997404,0.00003546799,0.00002956765,0.00007098089,0.00007210912,0.00005141944],"domain_scores_gemma":[0.9998724,0.00002969172,0.0000329407,0.000005906612,0.00003419892,0.00002485691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000349117,0.00006637885,0.00378816,0.01663602,0.0002069643,0.002576689,0.001655921,0.001904269,0.1132198,0.1557637,0.018535,0.685298],"study_design_scores_gemma":[0.00002464941,0.0004272281,0.01827811,0.002908483,0.0001476507,0.005079831,0.0007470778,0.0008275145,0.02606819,0.0422013,0.9032095,0.00008042309],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01524694,0.963001,0.005453321,0.002343511,0.0006925965,0.00002715149,0.0001562639,0.00006639754,0.01301283],"genre_scores_gemma":[0.1168335,0.8693072,0.003344721,0.00106966,0.0008875755,0.00006798087,0.0003021858,0.00002392389,0.008163176],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001609316,"threshold_uncertainty_score":0.005499005,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2076118717","doi":"10.1126/science.1226804","title":"<i>Hox</i> Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism","year":2012,"lang":"en","type":"article","venue":"Science","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":355,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Hox gene; Numerical digit; Turing; Biology; Mechanism (biology); Genetics; Phenotype; Gene; Evolutionary biology; Computer science; Mathematics; Physics; Arithmetic; Transcription factor","authors":[{"name":"Rushikesh Sheth","is_ca":false},{"name":"Luciano Marcon","is_ca":false},{"name":"María Félix Bastida","is_ca":false},{"name":"Marisa Junco","is_ca":false},{"name":"Laura Quintana","is_ca":false},{"name":"Randall D. Dahn","is_ca":false},{"name":"Marie Kmita","is_ca":true},{"name":"James Sharpe","is_ca":false},{"name":"María A. Ros","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007108342425190282,"gpt":0.2284783064269197,"spread":0.2213699640017294,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001089335,0.0001932568,0.0001477445,0.0001453648,0.0001471773,0.0003505614,0.0002008927,0.0001355967,0.0005840701],"category_scores_gemma":[0.0001567934,0.000181884,0.0001503207,0.0001071085,0.0005026186,0.0001438715,0.0002840041,0.0003328599,0.0002039261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002711549,"about_ca_system_score_gemma":0.0001373588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002761805,"about_ca_topic_score_gemma":0.0004754091,"domain_scores_codex":[0.9999208,0.00001001748,0.000006502336,0.0000225798,0.00002367731,0.00001623362],"domain_scores_gemma":[0.9998709,0.0000309352,0.00004947921,0.00001881378,0.000009960243,0.00001980874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002213224,0.000003049056,0.0005316946,0.000009123223,0.000001529213,0.00001885602,0.00001162495,0.0001903745,0.9976143,0.000613793,0.00001337302,0.0009702044],"study_design_scores_gemma":[0.00001223828,0.00005439162,0.0131297,0.000003289102,0.000009788107,0.0001740225,0.00002036992,0.002040778,0.9830022,0.0004137555,0.001133339,0.000006082619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98812,0.0002032791,0.009088448,0.00004539128,0.000005768983,0.00001020517,0.00007535896,0.000131199,0.002320235],"genre_scores_gemma":[0.9940891,0.0001677016,0.004517399,0.00002567819,0.000002892482,0.00001458747,0.00003825842,0.00002877601,0.001115637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005840701,"threshold_uncertainty_score":0.001967371,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2063093796","doi":"10.1038/ncb1058","title":"The large Maf factor Traffic Jam controls gonad morphogenesis in Drosophila","year":2003,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":335,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Somatic cell; Germline; Biology; Cell biology; Drosophila melanogaster; Transcription factor; Soma; Gonad; Morphogenesis; Genetics; Germ cell; Gene; Anatomy; Neuroscience","authors":[{"name":"Michelle A. Li","is_ca":true},{"name":"Jeffrey D. Alls","is_ca":true},{"name":"Rita M. Avancini","is_ca":true},{"name":"Karen Koo","is_ca":true},{"name":"Dorothea Godt","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003518904465587845,"gpt":0.2275611072972792,"spread":0.2240422028316913,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001058854,0.000331016,0.0001784888,0.0005669408,0.0004574254,0.0006470932,0.0003184082,0.0004341897,0.001127796],"category_scores_gemma":[0.000267557,0.0003464067,0.00016133,0.0001650818,0.0004051157,0.0005294643,0.0006276425,0.0008165062,0.0006528849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009054811,"about_ca_system_score_gemma":0.0002628922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0013913,"about_ca_topic_score_gemma":0.004209873,"domain_scores_codex":[0.9998801,0.00001235351,0.000006078153,0.00002649542,0.00003545692,0.00003958078],"domain_scores_gemma":[0.9997424,0.0000419526,0.00006565868,0.0000248717,0.00002852147,0.00009657958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007623745,0.000005497431,0.0003887782,0.00001459801,0.0000028261,0.00007073205,0.00001890974,0.00015125,0.996515,0.0008010506,0.00008548863,0.001869426],"study_design_scores_gemma":[0.00004527993,0.0001249535,0.04496948,0.00002082407,0.00003567619,0.0005263506,0.000193411,0.01025311,0.9332774,0.001502514,0.009020456,0.00003053089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901178,0.001597092,0.003791781,0.0001760577,0.00006089847,0.000008611226,0.0001757686,0.0002117281,0.00386027],"genre_scores_gemma":[0.9942889,0.0003548951,0.0009549064,0.00006767779,0.00001198897,0.000008598564,0.0001313834,0.00007897468,0.004102672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013913,"threshold_uncertainty_score":0.006569803,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1996468220","doi":"10.1016/j.cell.2009.02.025","title":"Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":330,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Ubiquitin; Wnt signaling pathway; Cell biology; Convergent extension; Ubiquitin-Protein Ligases; Neural tube; Deubiquitinating enzyme; Morphogenesis; Dishevelled; Cell polarity; Signal transduction; Cell; Ubiquitin ligase; Frizzled; Genetics; Gene; Embryogenesis; Embryo","authors":[{"name":"Masahiro Narimatsu","is_ca":true},{"name":"Rohit Bose","is_ca":true},{"name":"Melanie Pye","is_ca":true},{"name":"Liang Zhang","is_ca":true},{"name":"Bryan W. Miller","is_ca":true},{"name":"Peter V. Ching","is_ca":true},{"name":"Rui Sakuma","is_ca":true},{"name":"Valbona Luga","is_ca":true},{"name":"Luba Roncari","is_ca":true},{"name":"Liliana Attisano","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004390668221088379,"gpt":0.2074421868849088,"spread":0.2030515186638204,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002897526,0.0003745081,0.00025909,0.0003953848,0.0003205726,0.0006341644,0.0002121037,0.0002748019,0.0008872062],"category_scores_gemma":[0.0002389795,0.0001592881,0.0002295697,0.0001680248,0.0002975304,0.0003692436,0.0003803411,0.0002939235,0.0005493802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008184278,"about_ca_system_score_gemma":0.0002099616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008987606,"about_ca_topic_score_gemma":0.00191943,"domain_scores_codex":[0.9997891,0.00003862636,0.000009311217,0.00003046643,0.00004632269,0.00008615613],"domain_scores_gemma":[0.9998785,0.00001317557,0.00003691898,0.0000147211,0.00002639402,0.00003032526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003387491,0.00001309979,0.001098437,0.00004574735,0.0000137331,0.0001784996,0.00002656511,0.0002282591,0.9882514,0.002266835,0.0002770395,0.007261625],"study_design_scores_gemma":[0.00002174837,0.00008264373,0.009736555,0.000005514763,0.00001379008,0.000422658,0.00008618925,0.002701994,0.9793628,0.0005633457,0.006991917,0.00001084513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833236,0.006880519,0.004440968,0.000370338,0.0000378865,0.0000133871,0.0001845557,0.0001507226,0.00459805],"genre_scores_gemma":[0.9947214,0.00109694,0.001361311,0.00004530259,0.00001074062,0.000007258055,0.0001585177,0.00001462731,0.002583825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008987606,"threshold_uncertainty_score":0.005938172,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2990650992","doi":"10.1242/dev.182154","title":"Establishing neuronal diversity in the spinal cord: a time and a place","year":2019,"lang":"en","type":"review","venue":"Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":319,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"H2020 European Research Council; Wellcome Trust; Francis Crick Institute; Medical Research Council Canada; Cancer Research UK; Human Frontier Science Program","keywords":"Biology; Neuroscience; Spinal cord; Morphogen; Progenitor cell; Embryonic stem cell; Zebrafish; Vertebrate; Cell type; Floor plate; Progenitor; Anatomy; Gene; Cell; Stem cell; Cell biology; Genetics","authors":[{"name":"Andreas Sagner","is_ca":false},{"name":"James Briscoe","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04315496007722808,"gpt":0.2961015657021361,"spread":0.2529466056249081,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000349914,0.0007631664,0.001076623,0.002141184,0.0003156023,0.001189333,0.0008157215,0.001003532,0.002715032],"category_scores_gemma":[0.0004541364,0.0002612414,0.0002548402,0.002734734,0.0007029873,0.001868818,0.0008617669,0.001630746,0.002824079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007348186,"about_ca_system_score_gemma":0.001331262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008390121,"about_ca_topic_score_gemma":0.001300546,"domain_scores_codex":[0.9998921,0.00001289125,0.00001523272,0.00002351405,0.00004515285,0.00001102344],"domain_scores_gemma":[0.9998373,0.00006519741,0.00002292345,0.00000668778,0.00004221119,0.00002572564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004600277,0.00003518839,0.0001394809,0.01309172,0.00004176698,0.0001980275,0.00009112486,0.0003121981,0.003018799,0.01217033,0.02397856,0.9468767],"study_design_scores_gemma":[0.00000426184,0.00003609966,0.0004914924,0.001705848,0.00003215489,0.0005751321,0.00005591374,0.00003874406,0.0003995775,0.002933399,0.9937161,0.00001123043],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000131146,0.9971443,0.0002477541,0.0003109466,0.0001910321,0.000003613378,0.00002270734,0.00001380369,0.001934752],"genre_scores_gemma":[0.0004528612,0.9985455,0.0002231461,0.0001062664,0.00008878689,0.000004977299,0.00002174358,0.000001968396,0.0005547698],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002715032,"threshold_uncertainty_score":0.009082675,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2153293603","doi":"10.1200/jco.2011.39.1540","title":"Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":317,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre","funders":"Daiichi Sankyo Europe; American Society of Clinical Oncology","keywords":"Notch signaling pathway; Pharmacodynamics; Medicine; Pharmacokinetics; Dosing; Nausea; Pharmacology; Vomiting; Toxicity; Internal medicine; Oncology; Receptor","authors":[{"name":"Ian E. Krop","is_ca":true},{"name":"Tim Demuth","is_ca":true},{"name":"Tina Guthrie","is_ca":true},{"name":"Patrick Y. Wen","is_ca":true},{"name":"Warren Mason","is_ca":true},{"name":"Prakash Chinnaiyan","is_ca":true},{"name":"Nicholas Butowski","is_ca":true},{"name":"Morris D. Groves","is_ca":true},{"name":"Santosh Kesari","is_ca":true},{"name":"Steven J. Freedman","is_ca":true},{"name":"Samuel C. Blackman","is_ca":true},{"name":"James Watters","is_ca":true},{"name":"Andrey Loboda","is_ca":true},{"name":"Alexei A. Podtelezhnikov","is_ca":true},{"name":"Jared Lunceford","is_ca":true},{"name":"Cong Chen","is_ca":true},{"name":"Maxine Giannotti","is_ca":true},{"name":"Jeremy Hing","is_ca":true},{"name":"Robert A. Beckman","is_ca":true},{"name":"Patricia LoRusso","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02453945521365022,"gpt":0.4088820948697082,"spread":0.384342639656058,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005728452,0.0008624135,0.001232015,0.0002667725,0.000241491,0.0004461057,0.00043877,0.0005041172,0.001728265],"category_scores_gemma":[0.0004746355,0.0002729222,0.0005570265,0.0002620341,0.0004402786,0.000341325,0.0001829365,0.001589806,0.0005327195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005959075,"about_ca_system_score_gemma":0.0008937296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006524505,"about_ca_topic_score_gemma":0.001434423,"domain_scores_codex":[0.9998116,0.0000750782,0.00001267126,0.000028478,0.00002739384,0.00004478004],"domain_scores_gemma":[0.9996879,0.00004817293,0.00007073463,0.00002584469,0.00003221544,0.000135157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.303335,0.06730539,0.03803476,0.001085062,0.001653706,0.0007430297,0.0004905991,0.007369637,0.2987417,0.0005117174,0.008752755,0.2719766],"study_design_scores_gemma":[0.1503132,0.7430692,0.06532864,0.00005708283,0.0007065362,0.001440779,0.0001018804,0.004273607,0.02827303,0.000174842,0.006215459,0.00004574062],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960099,0.001436908,0.0005001687,0.0001677774,0.000028482,0.0005253761,0.000450796,0.00008833098,0.000792187],"genre_scores_gemma":[0.9950134,0.001021764,0.001239248,0.0003263276,0.00005485309,0.0005248817,0.001042775,0.00001562651,0.0007611099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001728265,"threshold_uncertainty_score":0.005781651,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2149186578","doi":"10.1002/dvdy.10248","title":"Old questions, new tools, and some answers to the mystery of fin regeneration","year":2003,"lang":"en","type":"review","venue":"Developmental Dynamics","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":312,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; Junta de Andalucía; Centre National de la Recherche Scientifique","keywords":"Blastema; Biology; Regeneration (biology); Zebrafish; Fish fin; Danio; Fin; Evolutionary biology; Fish <Actinopterygii>; Anatomy; Vertebrate; Mechanism (biology); Cell biology; Genetics; Gene; Epistemology; Fishery","authors":[{"name":"Marie‐Andrée Akimenko","is_ca":false},{"name":"Manuel Marí‐Beffa","is_ca":false},{"name":"José Becerra","is_ca":false},{"name":"Jacqueline Géraudie","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01942467635262474,"gpt":0.2683589457669533,"spread":0.2489342694143286,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001489337,0.001126142,0.001456008,0.002274248,0.0007750774,0.002025253,0.001705289,0.002300164,0.004742017],"category_scores_gemma":[0.001338093,0.0003933659,0.000404733,0.001972989,0.003377765,0.004924999,0.001062811,0.003295638,0.004965257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001257244,"about_ca_system_score_gemma":0.001491015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001265049,"about_ca_topic_score_gemma":0.00208689,"domain_scores_codex":[0.9996209,0.00007915384,0.00004868353,0.00007293378,0.0001453056,0.00003293401],"domain_scores_gemma":[0.9992455,0.0003952265,0.00005391676,0.0000469857,0.000162851,0.00009547113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001093902,0.00006631438,0.0002849807,0.008159172,0.0000471148,0.0007290901,0.000328827,0.0006070414,0.004588774,0.03279627,0.04802156,0.9042614],"study_design_scores_gemma":[0.000008190797,0.00003686008,0.0002831666,0.001221001,0.00001513373,0.001167556,0.000239696,0.00006144516,0.0004531528,0.01199556,0.9845006,0.00001762782],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009756257,0.9964503,0.0004881361,0.001138793,0.0004419374,0.000002056196,0.000008431021,0.00001352402,0.001359269],"genre_scores_gemma":[0.0009676403,0.9951357,0.0006782566,0.0007742986,0.00055364,0.000006698272,0.00001759424,0.000004817668,0.001861305],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004742017,"threshold_uncertainty_score":0.01586366,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2168524476","doi":"10.1017/s1464793102006097","title":"Descent with modification: the unity underlying homology and homoplasy as seen through an analysis of development and evolution","year":2003,"lang":"en","type":"review","venue":"Biological reviews/Biological reviews of the Cambridge Philosophical Society","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":303,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"","keywords":"Homology (biology); Ancestor; Evolutionary biology; Common descent; Biology; Parallel evolution; Similarity (geometry); Convergent evolution; Most recent common ancestor; Genetics; Phylogenetics; Gene; Phylogenetic tree; Geography; Computer science; Artificial intelligence","authors":[{"name":"Brian K. Hall","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1939148466713693,"gpt":0.3659942414104055,"spread":0.1720793947390362,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001979891,0.0005448524,0.001105023,0.002190205,0.001232856,0.004070283,0.001277591,0.001102496,0.001862744],"category_scores_gemma":[0.002940797,0.0002460625,0.000601223,0.003172238,0.01277636,0.008010774,0.002280269,0.002094836,0.0006613283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001524926,"about_ca_system_score_gemma":0.001889896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00126943,"about_ca_topic_score_gemma":0.00122743,"domain_scores_codex":[0.9978345,0.0007571815,0.0001877188,0.0005283773,0.0005498289,0.0001424183],"domain_scores_gemma":[0.9983189,0.001040394,0.0002382079,0.0001714727,0.0001581325,0.000072846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001848135,0.00002905948,0.005795334,0.005667767,0.0003247437,0.001877651,0.01275379,0.0008046649,0.008591209,0.5479268,0.009460149,0.4065841],"study_design_scores_gemma":[0.00001447512,0.000217112,0.01097526,0.00223862,0.0002045605,0.005687779,0.004693186,0.0006418875,0.002885208,0.4000876,0.5722556,0.00009876708],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04220154,0.8133028,0.06433441,0.01107086,0.00384135,0.0001163762,0.000323729,0.0003562235,0.06445277],"genre_scores_gemma":[0.4531836,0.4869174,0.03136511,0.008027786,0.003941651,0.0002480201,0.0005691877,0.000290269,0.01545703],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004070283,"threshold_uncertainty_score":0.01106417,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2043982544","doi":"10.1016/s0960-9822(01)00458-4","title":"Positional cloning of heart and soul reveals multiple roles for PKCλ in zebrafish organogenesis","year":2001,"lang":"en","type":"article","venue":"Current Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":287,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Heart, Lung, and Blood Institute","keywords":"Adherens junction; Biology; Cell biology; Neuroblast; Cell polarity; Zebrafish; Morphogenesis; Endoderm; Positional cloning; Genetic screen; Neural tube; Embryonic stem cell; Genetics; Phenotype; Embryo; Cadherin; Neurogenesis; Cell; Gene","authors":[{"name":"Sally Horne‐Badovinac","is_ca":false},{"name":"Dan Lin","is_ca":true},{"name":"Steve Waldron","is_ca":false},{"name":"Mónica Schwarz","is_ca":false},{"name":"Geraldine Mbamalu","is_ca":true},{"name":"Tony Pawson","is_ca":true},{"name":"Yuh Nung Jan","is_ca":false},{"name":"Didier Y. R. Stainier","is_ca":false},{"name":"Salim Abdelilah‐Seyfried","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01506277886204734,"gpt":0.2877113727124223,"spread":0.272648593850375,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000228132,0.0005657061,0.0002899618,0.001002752,0.0006500559,0.0007514016,0.0005812451,0.0004952066,0.002181726],"category_scores_gemma":[0.0002155797,0.0007257267,0.0004743822,0.0002327186,0.0008591613,0.0006417603,0.000584746,0.001163959,0.001307783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001293535,"about_ca_system_score_gemma":0.0007917213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004155062,"about_ca_topic_score_gemma":0.008489842,"domain_scores_codex":[0.9998097,0.000008673916,0.00001326755,0.0000613805,0.0000469068,0.00006010387],"domain_scores_gemma":[0.9995815,0.00005438632,0.0001321644,0.00004450607,0.00004197802,0.0001454649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001325983,0.00001040845,0.0005743008,0.00002221865,0.000003224227,0.0001155981,0.00003113279,0.00009887775,0.996107,0.001079222,0.0000438538,0.001781435],"study_design_scores_gemma":[0.00004928229,0.0000514124,0.0190862,0.00002162654,0.0000327962,0.0002774622,0.0001005236,0.001180313,0.9760605,0.0004137519,0.002711329,0.00001472615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830073,0.00134792,0.0103375,0.0003016976,0.00004880501,0.0000311542,0.0005449523,0.0001655906,0.004215152],"genre_scores_gemma":[0.9746052,0.0008685003,0.007525596,0.0001245478,0.00001887996,0.00004756926,0.0006737253,0.00009974507,0.01603625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004155062,"threshold_uncertainty_score":0.009385347,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1965963514","doi":"10.1073/pnas.091584598","title":"Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium","year":2001,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":287,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Medical Research and Materiel Command; U.S. Army; National Heart, Lung, and Blood Institute; American Heart Association; Medical Research Council; National Cancer Institute; National Institutes of Health","keywords":"Notch signaling pathway; Cell biology; Embryonic stem cell; Biology; Yolk sac; Endothelium; Cell fate determination; Hes3 signaling axis; Mutant; Embryogenesis; Embryo; Anatomy; Signal transduction; Genetics; Gene; Transcription factor","authors":[{"name":"Hendrik Uyttendaele","is_ca":true},{"name":"J.J.David Ho","is_ca":true},{"name":"Janet Rossant","is_ca":true},{"name":"Jan Kitajewski","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01653472756049089,"gpt":0.2591023641920046,"spread":0.2425676366315137,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001458851,0.000283539,0.0001660437,0.0003201945,0.000135946,0.0003116671,0.0002060606,0.0003025889,0.0009616517],"category_scores_gemma":[0.0003047222,0.0002107667,0.0001794763,0.0001282466,0.0003758142,0.0001373168,0.0002713486,0.000459008,0.0002243749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574604,"about_ca_system_score_gemma":0.0001586042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003516241,"about_ca_topic_score_gemma":0.0004682076,"domain_scores_codex":[0.9998263,0.00004111072,0.00002027436,0.00002888944,0.00005014044,0.00003332361],"domain_scores_gemma":[0.999637,0.00007584658,0.0001390207,0.00004923579,0.00002079086,0.00007812639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009002532,0.00001631636,0.0004462774,0.00001149014,0.000004763393,0.0004312305,0.00001336074,0.0001052173,0.9980647,0.0001982837,0.00001604095,0.0006022728],"study_design_scores_gemma":[0.00004375503,0.0002839863,0.01421339,0.000008070467,0.00003712238,0.003636061,0.00004168141,0.001266538,0.9790637,0.0002367711,0.00115939,0.000009532506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981304,0.0001913609,0.0009771769,0.00001910091,0.000004024022,0.000004710094,0.00007590941,0.0000382919,0.0005591252],"genre_scores_gemma":[0.9971193,0.0002042437,0.001112033,0.00001508152,0.000003175066,0.000008981538,0.0001468882,0.00001969742,0.001370651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009616517,"threshold_uncertainty_score":0.003217101,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2008081938","doi":"10.1016/s0301-472x(01)00757-3","title":"Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny","year":2002,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":283,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Medical Research Council; National Institutes of Health; Medical Research Council Canada","keywords":"Hox gene; Biology; Haematopoiesis; Stem cell; Progenitor cell; Embryonic stem cell; Homeobox; Cell biology; Gene expression; Molecular biology; Gene; Genetics","authors":[{"name":"Nicolas Pineault","is_ca":true},{"name":"Cheryl D. Helgason","is_ca":true},{"name":"H. Jeffrey Lawrence","is_ca":false},{"name":"R. Keith Humphries","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0104522765905947,"gpt":0.2559183114727622,"spread":0.2454660348821675,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001942228,0.0001638212,0.0002372328,0.0006213742,0.0002861425,0.0004395669,0.0001811087,0.0002313246,0.0006535623],"category_scores_gemma":[0.0002793241,0.0002859906,0.0001310291,0.000287392,0.0003586193,0.0003015849,0.0003013915,0.0005501861,0.0002525546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003094406,"about_ca_system_score_gemma":0.0002024761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005729598,"about_ca_topic_score_gemma":0.0008739058,"domain_scores_codex":[0.9998494,0.00002063695,0.00001159272,0.00003729805,0.00003228059,0.00004876507],"domain_scores_gemma":[0.999645,0.00009733083,0.00007242041,0.00003927948,0.00004951032,0.00009651815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000336381,0.00001174753,0.002003459,0.00002123642,0.000003355092,0.00005740499,0.0001045546,0.00007115961,0.9942865,0.0006112945,0.00002820335,0.002464802],"study_design_scores_gemma":[0.00001875044,0.0002871607,0.05879953,0.00001914741,0.00002685818,0.0003241897,0.0001247973,0.0005706071,0.9364268,0.0002420519,0.003151134,0.00000898622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937361,0.002088513,0.001852506,0.00002727637,0.000008010394,0.000009265602,0.000332175,0.00004478119,0.00190118],"genre_scores_gemma":[0.9904793,0.001076062,0.001739195,0.00004164602,0.00001103151,0.00003719805,0.0007249026,0.00004326216,0.005847442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006535623,"threshold_uncertainty_score":0.002245128,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1994245587","doi":"10.1038/nature01682","title":"Involvement of Notch and Delta genes in spider segmentation","year":2003,"lang":"en","type":"article","venue":"Nature","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":280,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Genetics","funders":"Deutsche Forschungsgemeinschaft","keywords":"Arthropod; Somitogenesis; Biology; Vertebrate; Evolutionary biology; Segmentation; Gene; Genetics; Notch signaling pathway; Artificial intelligence; Ecology; Computer science","authors":[{"name":"Angelika Stollewerk","is_ca":true},{"name":"Michael Schoppmeier","is_ca":false},{"name":"Wim G.M. Damen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005993069578850497,"gpt":0.2514903182624863,"spread":0.2454972486836358,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001491893,0.0002064987,0.0001956555,0.0003880223,0.0003415563,0.0008088131,0.0003304594,0.0004544734,0.0009471835],"category_scores_gemma":[0.000220517,0.0002734014,0.0001613814,0.0001661747,0.0005451875,0.0007135512,0.0004774275,0.000517901,0.0003228533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007157841,"about_ca_system_score_gemma":0.0003316588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006707358,"about_ca_topic_score_gemma":0.001248304,"domain_scores_codex":[0.9998746,0.0000152558,0.000008101358,0.00002637082,0.00004309743,0.00003248464],"domain_scores_gemma":[0.9998406,0.00002843942,0.00003212953,0.0000212072,0.00002600545,0.00005157965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002469924,0.0000120447,0.001413043,0.00004111008,0.000004491985,0.0002230861,0.00004071593,0.0002745715,0.9875728,0.004340712,0.00005738046,0.005773035],"study_design_scores_gemma":[0.0000420353,0.0001415118,0.03303533,0.00001658988,0.00002963267,0.00116851,0.0002508294,0.004040568,0.9494201,0.002913925,0.008923416,0.00001755041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816293,0.004051233,0.005425076,0.0002228605,0.00003220475,0.00001424936,0.0001750634,0.00006136279,0.008388687],"genre_scores_gemma":[0.9877694,0.001105299,0.00277692,0.00006642012,0.00001009618,0.00001006473,0.0002224128,0.00001928487,0.008019995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009471835,"threshold_uncertainty_score":0.005193353,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1985705162","doi":"10.1073/pnas.0806791105","title":"SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons","year":2008,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":275,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"RIKEN; March of Dimes Foundation; National Institutes of Health; Cincinnati Children's Hospital Medical Center; RIKEN Brain Science Institute; Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; Whitehall Foundation","keywords":"Subplate; Biology; Neocortex; Neuroscience; Cell biology; Cortex (anatomy)","authors":[{"name":"Kenneth Y. Kwan","is_ca":false},{"name":"Mandy M. Lam","is_ca":false},{"name":"Željka Krsnik","is_ca":false},{"name":"Yuka Imamura Kawasawa","is_ca":false},{"name":"Véronique Lefèbvre","is_ca":false},{"name":"Nenad Šestan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01940587372917321,"gpt":0.2596479532623122,"spread":0.240242079533139,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006573388,0.0002221025,0.00009363199,0.0001395956,0.0001323299,0.0002831228,0.0001103315,0.0001166088,0.0007925006],"category_scores_gemma":[0.0000854782,0.0001236837,0.0001175264,0.0000561502,0.0001994787,0.0001457764,0.0002236794,0.0002381356,0.0002678774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003607274,"about_ca_system_score_gemma":0.0001932657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001411904,"about_ca_topic_score_gemma":0.003679622,"domain_scores_codex":[0.9999083,0.0000069094,0.000006527679,0.00002068455,0.00002913842,0.00002848056],"domain_scores_gemma":[0.9999393,0.000005909216,0.00001672622,0.000005685288,0.000007857101,0.00002450157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004320691,0.000004549764,0.0009901773,0.00001212548,0.000002021519,0.00005716762,0.00002233764,0.00003099367,0.99714,0.0001941677,0.0000132102,0.001490045],"study_design_scores_gemma":[0.000008714583,0.00008511018,0.04160612,0.000008939776,0.00001373762,0.0002785146,0.0001147926,0.0007489985,0.9539465,0.000114809,0.003070484,0.000003161476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949198,0.0008377293,0.002202431,0.00002850743,0.0000117198,0.000004148555,0.0001009867,0.00003082925,0.001863756],"genre_scores_gemma":[0.9950913,0.000354688,0.0007701276,0.00001669884,0.000002903046,0.000004136935,0.0001904494,0.00001094491,0.003558682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001411904,"threshold_uncertainty_score":0.002807379,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2053219805","doi":"10.1016/j.cub.2005.01.048","title":"Smaug Recruits the CCR4/POP2/NOT Deadenylase Complex to Trigger Maternal Transcript Localization in the Early Drosophila Embryo","year":2005,"lang":"en","type":"article","venue":"Current Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":263,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Drosophila (subgenus); Embryo; Genetics; Repressor; Cell biology; Gene; Gene expression","authors":[{"name":"Jennifer L. Semotok","is_ca":true},{"name":"Ramona L. Cooperstock","is_ca":true},{"name":"Benjamin D. Pinder","is_ca":true},{"name":"Heli K. Vari","is_ca":true},{"name":"Howard D. Lipshitz","is_ca":true},{"name":"Craig A. Smibert","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04319004776998273,"gpt":0.3101400728947354,"spread":0.2669500251247527,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002193061,0.0003819007,0.000265358,0.0002463101,0.0003160965,0.000641348,0.0003303744,0.0003776845,0.001917255],"category_scores_gemma":[0.0002236696,0.0004216905,0.0002262278,0.0001043736,0.0003020099,0.0003952267,0.0005412568,0.001030608,0.001224715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009564133,"about_ca_system_score_gemma":0.0003786525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009166176,"about_ca_topic_score_gemma":0.003146533,"domain_scores_codex":[0.9998055,0.00002115731,0.0000115652,0.00004662768,0.00005800817,0.00005717265],"domain_scores_gemma":[0.999824,0.00002726264,0.00003313359,0.0000264406,0.00001929958,0.00006985249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009791389,0.000005038255,0.0002001096,0.00002314441,0.000002539293,0.00007727933,0.000006565987,0.00006258969,0.9983357,0.0002848111,0.00008073694,0.0008236009],"study_design_scores_gemma":[0.00001671,0.00003090861,0.004661414,0.000004279451,0.00000463878,0.0001384208,0.00001836732,0.001020294,0.9913327,0.00006669362,0.002701778,0.000003867309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820386,0.002238866,0.009748065,0.0003013852,0.0001050861,0.00003228388,0.0004663476,0.0003920306,0.004677313],"genre_scores_gemma":[0.9857319,0.0005247655,0.004120568,0.0001402662,0.00001636057,0.0000187009,0.000709788,0.0001799255,0.008557777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001917255,"threshold_uncertainty_score":0.006939292,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2125917793","doi":"10.1017/s1464793106007068","title":"Human cell type diversity, evolution, development, and classification with special reference to cells derived from the neural crest","year":2006,"lang":"en","type":"review","venue":"Biological reviews/Biological reviews of the Cambridge Philosophical Society","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":260,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cell type; Biology; Neural crest; Evolutionary biology; Computational biology; Cell; Genetics; Embryo","authors":[{"name":"Matthew K. Vickaryous","is_ca":true},{"name":"Brian K. Hall","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1539633258843227,"gpt":0.3151006902833715,"spread":0.1611373643990488,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005500491,0.0001298911,0.0002829881,0.002100708,0.0002928039,0.0008357912,0.0002312761,0.0003223003,0.004232819],"category_scores_gemma":[0.001252517,0.0001049125,0.0001985604,0.003718289,0.0005953665,0.0005004451,0.0004041381,0.000304622,0.00138049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004489941,"about_ca_system_score_gemma":0.0004196963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00274056,"about_ca_topic_score_gemma":0.002912061,"domain_scores_codex":[0.999638,0.00008072617,0.00003583343,0.00009596293,0.0001161782,0.0000332837],"domain_scores_gemma":[0.9996278,0.0001786266,0.00006503386,0.00004318478,0.00006647217,0.00001880818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001948316,0.00002067495,0.05133339,0.00145295,0.0001098889,0.001053472,0.001867638,0.0007577062,0.01047159,0.01657223,0.02896227,0.8872033],"study_design_scores_gemma":[0.00001209364,0.0001558738,0.2600763,0.0009057403,0.000145151,0.01629692,0.001156031,0.001566082,0.007984035,0.01911546,0.6925209,0.000065394],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1899361,0.6347162,0.05007278,0.004479384,0.0008444154,0.0001899867,0.009140478,0.0003792476,0.1102414],"genre_scores_gemma":[0.6491368,0.274495,0.03544011,0.001764425,0.0009446942,0.0002017933,0.008078682,0.0001187555,0.02981965],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004232819,"threshold_uncertainty_score":0.01416022,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1997450219","doi":"10.1242/dev.007567","title":"Hox patterning of the vertebrate rib cage","year":2007,"lang":"en","type":"article","venue":"Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":258,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre hospitalier de l'Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; March of Dimes Foundation","keywords":"Hox gene; Somite; Biology; Paraxial mesoderm; Homeotic gene; Anatomy; Axial skeleton; Lateral plate mesoderm; Mesoderm; Rib cage; NODAL; Intermediate mesoderm; Genetics; Embryogenesis; Phenotype; Embryo; Embryonic stem cell; Gene","authors":[{"name":"Daniel C. McIntyre","is_ca":false},{"name":"Sabita Rakshit","is_ca":false},{"name":"Alisha R. Yallowitz","is_ca":false},{"name":"Luke C. Loken","is_ca":false},{"name":"Lucie Jeannotte","is_ca":true},{"name":"Mario R. Capecchi","is_ca":false},{"name":"Deneen M. Wellik","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004949100094699063,"gpt":0.2132749602897776,"spread":0.2083258601950785,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006444227,0.0001636815,0.0001797853,0.0003480416,0.000284684,0.0003384223,0.0002048012,0.0002564784,0.001616044],"category_scores_gemma":[0.000160867,0.0002254856,0.0002240377,0.0001381313,0.0004852557,0.0001344349,0.0003829739,0.000340859,0.001076823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002894684,"about_ca_system_score_gemma":0.000248638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001281721,"about_ca_topic_score_gemma":0.002509506,"domain_scores_codex":[0.9998128,0.00001685415,0.000009568885,0.0000512132,0.00007441344,0.00003523476],"domain_scores_gemma":[0.9998842,0.00001237185,0.00002540012,0.00002028209,0.00003022827,0.00002736489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004053598,0.000003750137,0.001489196,0.00002479333,0.000004451911,0.0001387768,0.00004783577,0.000345428,0.9910386,0.001720542,0.0002263172,0.00491963],"study_design_scores_gemma":[0.00003619324,0.0005514556,0.2274665,0.00008083613,0.0000392414,0.004046934,0.0002526117,0.005899461,0.7284455,0.001666842,0.03145997,0.00005437115],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9321947,0.001412974,0.0257549,0.0001273973,0.00003306403,0.00004680596,0.0009361513,0.0005920658,0.0389019],"genre_scores_gemma":[0.9817857,0.0003402277,0.005585383,0.00005318338,0.000006424461,0.00002090695,0.0006161927,0.0001077964,0.0114841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001616044,"threshold_uncertainty_score":0.005406141,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2152274458","doi":"10.1242/dev.128.18.3623","title":"The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm","year":2001,"lang":"en","type":"article","venue":"Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":250,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Gastrulation; Epiblast; Biology; Primitive streak; Mesoderm; Notochord; Germ layer; Cell biology; Lateral plate mesoderm; Population; Histogenesis; Embryo; Intermediate mesoderm; Anatomy; Embryogenesis; Embryonic stem cell; Genetics; Induced pluripotent stem cell; Immunology","authors":[{"name":"Simon J. Kinder","is_ca":false},{"name":"Tania E. Tsang","is_ca":false},{"name":"Maki Wakamiya","is_ca":false},{"name":"Hiroshi Sasaki","is_ca":false},{"name":"Richard R. Behringer","is_ca":false},{"name":"András Nagy","is_ca":true},{"name":"Patrick Tam","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005339918224596452,"gpt":0.2242195514560185,"spread":0.218879633231422,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008881206,0.0004235223,0.0001985894,0.0006927882,0.0002711986,0.0003662928,0.0001753071,0.0001957893,0.0031829],"category_scores_gemma":[0.00007670692,0.00024731,0.0002366066,0.000185363,0.000217058,0.0001393082,0.0003192194,0.0003776174,0.001166527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002127116,"about_ca_system_score_gemma":0.0002630808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000859649,"about_ca_topic_score_gemma":0.001573595,"domain_scores_codex":[0.9998922,0.000007929058,0.000004348406,0.000030836,0.0000469156,0.00001771648],"domain_scores_gemma":[0.9999267,0.000002798101,0.00001884948,0.00001061933,0.000009426,0.0000316868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001029031,0.00001339044,0.001367952,0.00004279742,0.00001205525,0.00009334516,0.00004525338,0.00003901784,0.9884418,0.00074966,0.0005045186,0.008587373],"study_design_scores_gemma":[0.0001371591,0.001051837,0.2721346,0.0001303158,0.0001662808,0.003106694,0.0001735565,0.001702294,0.5313258,0.001130255,0.1889079,0.00003328295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9421673,0.008129436,0.02420557,0.0002077835,0.0001637232,0.0001615572,0.00397728,0.001627117,0.01936021],"genre_scores_gemma":[0.9294601,0.002470356,0.01199668,0.0001603886,0.00006142458,0.0002296098,0.00743088,0.0002209682,0.04796959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0031829,"threshold_uncertainty_score":0.01064783,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029189567","doi":"10.1242/dev.02271","title":"Wnt signals mediate a fate decision between otic placode and epidermis","year":2006,"lang":"en","type":"article","venue":"Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":244,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute on Deafness and Other Communication Disorders","keywords":"Biology; Wnt signaling pathway; Cell biology; Epidermis (zoology); Inner ear; Cell fate determination; Transcription factor; Anatomy; Signal transduction; Genetics; Gene","authors":[{"name":"Takahiro Ohyama","is_ca":false},{"name":"Othman A. Mohamed","is_ca":true},{"name":"Makoto M. Taketo","is_ca":false},{"name":"Daniel Dufort","is_ca":true},{"name":"Andrew K. Groves","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007930258390642944,"gpt":0.2343460630281129,"spread":0.22641580463747,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014172,0.0003498439,0.0001501542,0.0002186149,0.0002808783,0.0007739526,0.0001850568,0.0002836428,0.001131918],"category_scores_gemma":[0.000180198,0.0002665366,0.0001361752,0.0001226277,0.0003241947,0.0004597288,0.0003781039,0.0003111582,0.0005097934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004129026,"about_ca_system_score_gemma":0.0002801226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009788778,"about_ca_topic_score_gemma":0.002292168,"domain_scores_codex":[0.9998502,0.00001833279,0.000006766481,0.00002389737,0.00005431545,0.00004648519],"domain_scores_gemma":[0.9999328,0.000009475512,0.00001372703,0.000004812518,0.00001310676,0.00002615557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001034643,0.000005832051,0.0008267688,0.00002141208,0.00000352992,0.0001810564,0.00003033387,0.000092287,0.9950449,0.001317077,0.00007365408,0.002299563],"study_design_scores_gemma":[0.0000501943,0.0001313261,0.0176656,0.00001709786,0.00001958245,0.0006443923,0.0002076753,0.002358553,0.9720858,0.0007068177,0.006102087,0.00001088868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97478,0.002655555,0.00717556,0.0001767841,0.00005137591,0.00003485613,0.0001682323,0.0001150316,0.01484255],"genre_scores_gemma":[0.9916193,0.0007810545,0.001681379,0.00002735024,0.00001106775,0.000008946131,0.00009517791,0.00001128122,0.005764339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001131918,"threshold_uncertainty_score":0.003786683,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2007271403","doi":"10.1016/s0378-1119(01)00485-1","title":"Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development","year":2001,"lang":"en","type":"review","venue":"Gene","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":235,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Biology; Transcription factor; Cell biology; Homeobox; Genetics; Histone deacetylase; Histone; Gene; Molecular biology","authors":[{"name":"Alain Nepveu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01497307650260604,"gpt":0.231202760571364,"spread":0.2162296840687579,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006857942,0.001096772,0.001467881,0.001235027,0.0003658595,0.0009443581,0.001459559,0.001210185,0.00255223],"category_scores_gemma":[0.0004719578,0.0003163956,0.0002660037,0.00185876,0.0007848645,0.001441326,0.0006073435,0.001661262,0.002766239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008755536,"about_ca_system_score_gemma":0.0009878691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001221075,"about_ca_topic_score_gemma":0.002360226,"domain_scores_codex":[0.9998715,0.00001200465,0.00001700799,0.00003336111,0.0000503624,0.00001563079],"domain_scores_gemma":[0.9997321,0.000104978,0.00003091371,0.00001217065,0.00007685874,0.00004304823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000160559,0.00005263336,0.0001905859,0.005812329,0.00005263822,0.0004857562,0.00005868143,0.0004715932,0.01169094,0.005052696,0.0360711,0.9399006],"study_design_scores_gemma":[0.00002556078,0.00006016522,0.0004882544,0.0005244918,0.00006610567,0.001394397,0.00004864125,0.00009184676,0.002426192,0.001673638,0.9931858,0.00001487842],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002927039,0.9962512,0.0008893191,0.0002964774,0.0005774187,0.000006265101,0.00002674544,0.0000202598,0.001639678],"genre_scores_gemma":[0.00171982,0.9939956,0.001100198,0.0003164199,0.0003696402,0.00001155048,0.00007105587,0.000004422046,0.00241138],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00255223,"threshold_uncertainty_score":0.008538067,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1976813254","doi":"10.1111/j.1469-7580.2008.01043.x","title":"The integumentary skeleton of tetrapods: origin, evolution, and development","year":2009,"lang":"en","type":"review","venue":"Journal of Anatomy","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":221,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Guelph","funders":"Core Research for Evolutional Science and Technology","keywords":"Integumentary system; Biology; Tetrapod (structure); Anatomy; Neural crest; Evolutionary biology; Vertebrate; Body plan; Axial skeleton; Paleontology; Cell biology; Genetics","authors":[{"name":"Matthew K. Vickaryous","is_ca":true},{"name":"Jean‐Yves Sire","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0128546347733257,"gpt":0.3086860625084182,"spread":0.2958314277350925,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475697,0.0002426661,0.0001965974,0.0006914911,0.0003285078,0.0006043043,0.0002670636,0.0003115331,0.001307168],"category_scores_gemma":[0.0001438498,0.0001152018,0.0001138994,0.0007424548,0.0005001354,0.0005827848,0.0004637761,0.000298152,0.0004511175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002998418,"about_ca_system_score_gemma":0.0002560072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002019122,"about_ca_topic_score_gemma":0.002410008,"domain_scores_codex":[0.9999217,0.000005808784,0.000007433092,0.00003711524,0.00002012558,0.000007908548],"domain_scores_gemma":[0.9999251,0.000007223413,0.00002234162,0.00000969466,0.00001982913,0.00001589876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002900901,0.00006001633,0.1773877,0.0009940927,0.00007388135,0.0008078422,0.0009356497,0.001002863,0.4388495,0.003207028,0.0004797453,0.3759116],"study_design_scores_gemma":[0.000004887373,0.0002810729,0.9737801,0.0001090682,0.00004440099,0.002167141,0.0003521641,0.0008045945,0.006839278,0.001114074,0.01448262,0.00002063704],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9478698,0.03665599,0.006217938,0.0002328038,0.00002965442,0.00003493945,0.0007294152,0.00008003052,0.008149427],"genre_scores_gemma":[0.9555955,0.02435877,0.01351728,0.000148146,0.00006078966,0.00002987289,0.001383435,0.00003256015,0.004873538],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002019122,"threshold_uncertainty_score":0.004372895,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109179142","doi":"10.1128/mcb.24.20.8813-8822.2004","title":"Notch Activation Induces Endothelial Cell Cycle Arrest and Participates in Contact Inhibition: Role of p21 <sup>Cip1</sup> Repression","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Michael Smith Health Research BC; Fondazione Italiana per la Ricerca sul Cancro; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Notch signaling pathway; Cell biology; Downregulation and upregulation; Biology; Cyclin A; Retinoblastoma protein; Phosphorylation; Angiogenesis; Cyclin D; Cell cycle; Cyclin A2; Psychological repression; Endothelial stem cell; Cyclin; Signal transduction; Cancer research; Cell; Cyclin-dependent kinase 2; Protein kinase A; Biochemistry; Gene expression","authors":[{"name":"Michela Noseda","is_ca":true},{"name":"Linda Chang","is_ca":false},{"name":"Graeme W. McLean","is_ca":false},{"name":"Jonathan E. Grim","is_ca":false},{"name":"Bruce E. Clurman","is_ca":false},{"name":"Laura L. Smith","is_ca":false},{"name":"Aly Karsan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00512924131541998,"gpt":0.2189044565390726,"spread":0.2137752152236526,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008396264,0.0002682139,0.000158653,0.0003078193,0.0003131662,0.0004268869,0.0001979528,0.0001970439,0.002245684],"category_scores_gemma":[0.0001470204,0.0001113637,0.0001619678,0.0001622307,0.0001788534,0.0002208326,0.0002432071,0.0003670249,0.0005739094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000555033,"about_ca_system_score_gemma":0.0001920613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008526882,"about_ca_topic_score_gemma":0.00123697,"domain_scores_codex":[0.999881,0.00001645489,0.00000913393,0.00001818575,0.00003636577,0.00003880167],"domain_scores_gemma":[0.9998777,0.00002446994,0.00002810146,0.00001822789,0.00001890146,0.00003251288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001975958,0.00004642737,0.0003704445,0.00004644597,0.000004461345,0.0001710716,0.00001736238,0.00008911449,0.9955141,0.0005530229,0.0001335742,0.002856417],"study_design_scores_gemma":[0.00001547252,0.00008954921,0.00926716,0.000003799214,0.000006101763,0.0003304484,0.00001435304,0.00121555,0.9857445,0.0001331084,0.003177514,0.000002397524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876899,0.00303739,0.002956415,0.0001600673,0.00002805738,0.0000385557,0.0004919815,0.0001307521,0.005466961],"genre_scores_gemma":[0.9940102,0.0008323085,0.0007314047,0.00003287038,0.0000127636,0.00003402868,0.0004882232,0.00001277291,0.00384536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002245684,"threshold_uncertainty_score":0.007512569,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2082983359","doi":"10.1074/jbc.m109.014845","title":"Numb Regulates Post-endocytic Trafficking and Degradation of Notch1","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Hospital for Sick Children","keywords":"NUMB; Endocytic cycle; Cell biology; Degradation (telecommunications); Chemistry; Endocytosis; Biology; Biochemistry; Computer science; Cell","authors":[{"name":"Melanie A. McGill","is_ca":true},{"name":"Sascha E. Dho","is_ca":true},{"name":"Gerry Weinmaster","is_ca":false},{"name":"C. Jane McGlade","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0109313053960882,"gpt":0.2404798941111409,"spread":0.2295485887150527,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000134708,0.0001885494,0.0001838826,0.0001651845,0.000343103,0.0004758216,0.0001535136,0.0001498558,0.0008998335],"category_scores_gemma":[0.0001883129,0.0001568803,0.0001142319,0.00009746711,0.0002467781,0.0002417746,0.0003269706,0.0002556323,0.0004501581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007585139,"about_ca_system_score_gemma":0.0002301803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008495472,"about_ca_topic_score_gemma":0.001371327,"domain_scores_codex":[0.9998765,0.00002177022,0.00001014357,0.00002347666,0.00003777683,0.00003038199],"domain_scores_gemma":[0.9999101,0.000008258877,0.00002726021,0.000007157557,0.00001303433,0.00003412004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001283638,0.00001145949,0.0005331808,0.00002788275,0.00000373272,0.00008792288,0.00001805064,0.0001091384,0.9969261,0.0003607135,0.00006066693,0.001732759],"study_design_scores_gemma":[0.00001996021,0.000071667,0.01986453,0.00002005856,0.00001301732,0.0004019629,0.0000756204,0.002986773,0.9713002,0.0002673785,0.004973113,0.000005795278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897042,0.005402629,0.001729158,0.0001246869,0.00002498753,0.000007506138,0.0001294011,0.00005054726,0.00282681],"genre_scores_gemma":[0.9946248,0.001295368,0.0006493556,0.00002739397,0.000004181831,0.000009287181,0.0001098126,0.00001778729,0.00326206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008998335,"threshold_uncertainty_score":0.005503416,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2100898236","doi":"10.1038/nature11804","title":"Scaling of embryonic patterning based on phase-gradient encoding","year":2012,"lang":"en","type":"article","venue":"Nature","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":217,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Biology; Embryo; Mesoderm; Cell biology; Embryonic stem cell; Morphogenesis; Vertebrate; Developmental biology; Ex vivo; Genetics; Gene; In vivo","authors":[{"name":"Volker M. Lauschke","is_ca":false},{"name":"Charisios D. Tsiairis","is_ca":false},{"name":"Paul François","is_ca":true},{"name":"Alexander Aulehla","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007758067268760218,"gpt":0.273967362136383,"spread":0.2662092948676228,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001931299,0.0003251989,0.0002729722,0.0003453066,0.0001971675,0.0008518323,0.0002980678,0.0002377878,0.002144067],"category_scores_gemma":[0.001031385,0.0003264081,0.0001438917,0.0002186426,0.0002924055,0.0005152814,0.0004526011,0.0004855481,0.0005623059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004494649,"about_ca_system_score_gemma":0.0001848848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002717724,"about_ca_topic_score_gemma":0.0005261374,"domain_scores_codex":[0.9998629,0.00001974028,0.00000925526,0.00003501744,0.0000531586,0.00001980016],"domain_scores_gemma":[0.999333,0.0002071169,0.0001473381,0.0001338464,0.00008404591,0.0000947126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007572985,0.00001646277,0.0003877325,0.00001346975,0.000002862417,0.00001469739,0.00001143898,0.0004331213,0.9898621,0.002668501,0.0001184832,0.006395358],"study_design_scores_gemma":[0.0000519211,0.0001612522,0.0202345,0.00001629783,0.00001862792,0.0002155089,0.00004403794,0.03236752,0.9381243,0.00551251,0.003214474,0.00003907075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9597182,0.001042335,0.0282729,0.0003813668,0.0001225654,0.00002740282,0.0002846595,0.0004474316,0.009703075],"genre_scores_gemma":[0.9930111,0.0004104795,0.004486107,0.00008328469,0.0000327024,0.00001936884,0.0001519997,0.0001749599,0.001630074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002144067,"threshold_uncertainty_score":0.007172644,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4320300899","doi":"10.1523/jneurosci.22-17-07627.2002","title":"Distinct Actions of<i>Emx1</i>,<i>Emx2</i>, and<i>Pax6</i>in Regulating the Specification of Areas in the Developing Neocortex","year":2002,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":215,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; McKnight Foundation","keywords":"EMX2; Neocortex; PAX6; Neuroscience; Biology; Cell biology; Transcription factor; Homeobox; Genetics; Gene","authors":[{"name":"Kathie M. Bishop","is_ca":false},{"name":"John L.R. Rubenstein","is_ca":false},{"name":"Dennis D.M. O’Leary","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03959389497917874,"gpt":0.2725273621050643,"spread":0.2329334671258856,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002111356,0.0002454228,0.0001949164,0.0004000463,0.0002332755,0.000488723,0.0002876041,0.0002448817,0.000789067],"category_scores_gemma":[0.0002229748,0.0001859091,0.0003184167,0.0001980029,0.0005098371,0.0004892066,0.000429178,0.0004383365,0.0001581033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002262645,"about_ca_system_score_gemma":0.0002104393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006263321,"about_ca_topic_score_gemma":0.001302157,"domain_scores_codex":[0.9998164,0.00001885221,0.00001587572,0.00004852033,0.00005513743,0.00004526091],"domain_scores_gemma":[0.9998993,0.00001893822,0.00002207672,0.00001144576,0.00001103726,0.00003717076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001948099,0.00001908352,0.002798002,0.0000539911,0.00001042292,0.0001227256,0.00006537816,0.0003143849,0.990954,0.0007882582,0.00003454877,0.00464433],"study_design_scores_gemma":[0.00005162401,0.0004221665,0.1339114,0.00004102493,0.00007341745,0.0007964743,0.0005003122,0.002631694,0.8560384,0.0006581107,0.004848568,0.00002676798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906591,0.00270593,0.002171815,0.00007303964,0.00001397313,0.00002244735,0.000202298,0.00002219426,0.004129234],"genre_scores_gemma":[0.9920663,0.002161415,0.002481814,0.0001491234,0.00001144658,0.00004994505,0.0003627239,0.00001245395,0.002704706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000789067,"threshold_uncertainty_score":0.002639711,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2788408124","doi":"10.1016/j.cell.2018.01.026","title":"Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation","year":2018,"lang":"en","type":"article","venue":"Cell","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":209,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"European Research Council; Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Marie Curie; European Molecular Biology Laboratory; Simons Foundation","keywords":"Biology; Mesoderm; Wnt signaling pathway; Notch signaling pathway; Cell biology; Modulation (music); FGF and mesoderm formation; Signal transduction; Neuroscience; Genetics; Gene; Embryonic stem cell; Physics","authors":[{"name":"Katharina F. Sonnen","is_ca":false},{"name":"Volker M. Lauschke","is_ca":false},{"name":"Julia Uraji","is_ca":false},{"name":"Henning J. Falk","is_ca":false},{"name":"Yvonne Petersen","is_ca":false},{"name":"Maja C. Funk","is_ca":false},{"name":"Mathias Beaupeux","is_ca":true},{"name":"Paul François","is_ca":true},{"name":"Christoph A. Merten","is_ca":false},{"name":"Alexander Aulehla","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01207099118825714,"gpt":0.2739742461205284,"spread":0.2619032549322713,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001349801,0.0001858045,0.0001587051,0.0002313855,0.000147341,0.000626559,0.0002771761,0.0002522276,0.001815746],"category_scores_gemma":[0.0004297378,0.0002651319,0.0001280981,0.0001236183,0.0002327447,0.0004160106,0.0003375275,0.0003258071,0.0004771111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003843628,"about_ca_system_score_gemma":0.0001863343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002408033,"about_ca_topic_score_gemma":0.0005875338,"domain_scores_codex":[0.9998949,0.00001619358,0.000005570357,0.00002986237,0.00002526833,0.00002814593],"domain_scores_gemma":[0.9998407,0.00003441492,0.00004390407,0.00001325242,0.00002380192,0.00004392253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001923986,0.000008677173,0.0004312629,0.00001065872,0.000002636861,0.0000170347,0.00001560068,0.00008151626,0.9962316,0.0006698895,0.00004124253,0.002297544],"study_design_scores_gemma":[0.0001377896,0.0002184158,0.0581788,0.00002450204,0.00004061529,0.0001738976,0.0001822115,0.01495024,0.9198101,0.001636065,0.004620642,0.00002670519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850954,0.0009003207,0.009632465,0.0001861801,0.000106128,0.00001557048,0.0001726573,0.0001290091,0.003762163],"genre_scores_gemma":[0.9963554,0.0003175585,0.00121067,0.00004702294,0.00002603519,0.00001393558,0.0001018422,0.00004002586,0.001887596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001815746,"threshold_uncertainty_score":0.00607425,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2148498486","doi":"10.1186/jbiol130","title":"Conservation of core gene expression in vertebrate tissues","year":2009,"lang":"en","type":"article","venue":"Journal of Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":196,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto","funders":"National Institute of General Medical Sciences; Howard Hughes Medical Institute","keywords":"Biology; Gene; Conserved sequence; Vertebrate; Gene expression; Genetics; Regulatory sequence; Regulation of gene expression; Evolutionary biology; Body plan; Peptide sequence","authors":[{"name":"Esther T. Chan","is_ca":true},{"name":"Gerald Quon","is_ca":true},{"name":"Gordon Chua","is_ca":true},{"name":"Tomas Babak","is_ca":true},{"name":"Miles Trochesset","is_ca":true},{"name":"Ralph Zirngibl","is_ca":true},{"name":"Jane E. Aubin","is_ca":true},{"name":"Michael J. H. Ratcliffe","is_ca":true},{"name":"Andrew Wilde","is_ca":true},{"name":"Michael Brudno","is_ca":true},{"name":"Quaid Morris","is_ca":true},{"name":"Timothy R. Hughes","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01408293672775333,"gpt":0.2801367255944027,"spread":0.2660537888666493,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002760658,0.0002059085,0.0002929771,0.0007475502,0.0002214569,0.0004015761,0.0002836907,0.0002380233,0.001218472],"category_scores_gemma":[0.0006628471,0.0001284392,0.000163739,0.00038095,0.0004240284,0.0002254398,0.0003124644,0.0002020612,0.0003854779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002471737,"about_ca_system_score_gemma":0.0001942604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005455527,"about_ca_topic_score_gemma":0.0006771235,"domain_scores_codex":[0.9996599,0.00002858403,0.00002869929,0.000173811,0.00006193169,0.00004701837],"domain_scores_gemma":[0.9991304,0.0002173014,0.0002643197,0.0001031014,0.0001548128,0.0001300313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001758006,0.00001665246,0.03662711,0.0001172593,0.00003412148,0.00009955874,0.000115001,0.0001892681,0.956313,0.0002687079,0.00004406443,0.005999553],"study_design_scores_gemma":[0.0000124623,0.0004277334,0.8130642,0.00004722219,0.00009956701,0.001899118,0.0001654229,0.001603337,0.1799599,0.0005698689,0.002134016,0.00001716295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945877,0.000916718,0.002813392,0.00002311049,0.000003830045,0.00000860004,0.0004284112,0.00004919913,0.001169156],"genre_scores_gemma":[0.9959944,0.0001915423,0.00247685,0.0000281044,0.000005869099,0.00001700564,0.00082611,0.00001985106,0.0004402412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001218472,"threshold_uncertainty_score":0.004076183,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2047483387","doi":"10.1046/j.1525-142x.2000.00032.x","title":"The neural crest as a fourth germ layer and vertebrates as quadroblastic not triploblastic","year":2000,"lang":"en","type":"article","venue":"Evolution & Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Dalhousie University","funders":"","keywords":"Nova scotia; Demise; Neural crest; Biology; Classics; Art history; Library science; Zoology; Art; History; Computer science; Genetics; Law; Archaeology; Political science; Embryo","authors":[{"name":"Brian K. Hall","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00616614953004755,"gpt":0.2253534847796179,"spread":0.2191873352495703,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001900718,0.0001415194,0.0001648319,0.0003592823,0.0004585266,0.001341806,0.0004571468,0.000439196,0.001474586],"category_scores_gemma":[0.0003012501,0.0002060589,0.0001490834,0.0002691736,0.00128253,0.0007664747,0.0005851581,0.0006703677,0.000561008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003774286,"about_ca_system_score_gemma":0.0004004055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001198572,"about_ca_topic_score_gemma":0.003527172,"domain_scores_codex":[0.9997956,0.00002679663,0.00001759514,0.0000604334,0.00006303532,0.00003643167],"domain_scores_gemma":[0.9997,0.00002663532,0.00008857102,0.00006901379,0.00005133494,0.00006450251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000383422,0.000009581658,0.01158866,0.0002071604,0.00003344818,0.000991158,0.0004928385,0.0004815264,0.8757682,0.07272239,0.0006624247,0.03665914],"study_design_scores_gemma":[0.00008953447,0.0009771212,0.223883,0.0002460138,0.0003579408,0.02067539,0.00211903,0.004366503,0.4362223,0.03811493,0.2728132,0.0001351151],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9252309,0.010463,0.02246161,0.0007015981,0.0003218249,0.00002321193,0.000232872,0.0002088152,0.04035615],"genre_scores_gemma":[0.9707946,0.002019895,0.009588998,0.0002001288,0.00003211906,0.00001252067,0.0002029851,0.00004312404,0.01710555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001474586,"threshold_uncertainty_score":0.004933,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044766358","doi":"10.1016/s1074-7613(01)00189-3","title":"Subversion of the T/B Lineage Decision in the Thymus by Lunatic Fringe-Mediated Inhibition of Notch-1","year":2001,"lang":"en","type":"article","venue":"Immunity","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"University of British Columbia","keywords":"Biology; Notch signaling pathway; Cell biology; Lineage (genetic); Lunatic; Function (biology); Notch 1; Progenitor cell; Stem cell; Signal transduction; Genetics; Gene; Law","authors":[{"name":"Ute Koch","is_ca":true},{"name":"Tyler A Lacombe","is_ca":true},{"name":"Dianne Holland","is_ca":true},{"name":"Jennifer L Bowman","is_ca":true},{"name":"Brenda Cohen","is_ca":true},{"name":"Sean E. Egan","is_ca":true},{"name":"Cynthia J. Guidos","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005540430872924887,"gpt":0.2261364390394341,"spread":0.2205960081665092,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000216349,0.0002018406,0.000250991,0.0002574908,0.00024383,0.0005421325,0.0003113018,0.000209358,0.001717121],"category_scores_gemma":[0.0001965434,0.0001668705,0.0001987815,0.0001028917,0.0003453515,0.0001930051,0.0003042015,0.0008885387,0.0004877093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004939231,"about_ca_system_score_gemma":0.0003132752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009072626,"about_ca_topic_score_gemma":0.002086173,"domain_scores_codex":[0.9998438,0.00002830862,0.00001104025,0.00002147255,0.0000250795,0.00007026934],"domain_scores_gemma":[0.9998376,0.00002119737,0.00003583297,0.00002147,0.0000101163,0.00007365859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004425036,0.00002338383,0.00008918335,0.00002134833,0.000004651637,0.00003762815,0.00001023545,0.00008231476,0.9978305,0.0002731875,0.00004093502,0.001144145],"study_design_scores_gemma":[0.00007047525,0.0002368372,0.002743355,0.000005020949,0.00001652354,0.0001452769,0.00004890774,0.001119701,0.9934502,0.0001386115,0.00201827,0.000006804938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946814,0.001734593,0.001558185,0.0001265832,0.00003409897,0.00001093093,0.000144045,0.00008572586,0.001624385],"genre_scores_gemma":[0.996285,0.0003954526,0.0008749761,0.00004107481,0.00001213592,0.00001244422,0.0001306887,0.00002115173,0.00222706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001717121,"threshold_uncertainty_score":0.005744338,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2069014283","doi":"10.1016/j.devcel.2007.10.016","title":"Live Imaging and Genetic Analysis of Mouse Notochord Formation Reveals Regional Morphogenetic Mechanisms","year":2007,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":190,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Notochord; Biology; Convergent extension; Vertebrate; Cell biology; Morphogenesis; FOXA2; Anatomy; Embryo; Zebrafish; Genetics; Embryogenesis; Embryonic stem cell; Gastrulation; Gene","authors":[{"name":"Yojiro Yamanaka","is_ca":true},{"name":"Owen J. Tamplin","is_ca":true},{"name":"Anja Beckers","is_ca":false},{"name":"Achim Gossler","is_ca":false},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006414356460333184,"gpt":0.2150669700657776,"spread":0.2086526136054444,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003908926,0.0005066328,0.0004508106,0.0008349677,0.000671997,0.0007492304,0.000978358,0.0007759436,0.001901596],"category_scores_gemma":[0.0003737131,0.0006875631,0.0004053388,0.0002927567,0.0008128285,0.0007921642,0.0006033237,0.001834187,0.0008755444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001018806,"about_ca_system_score_gemma":0.0004951596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002659391,"about_ca_topic_score_gemma":0.005704633,"domain_scores_codex":[0.9996557,0.00002946416,0.00001902066,0.0001111332,0.00009670033,0.00008801676],"domain_scores_gemma":[0.9995659,0.00009368449,0.0001243702,0.0000872181,0.00004937654,0.00007946313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003934476,0.00001059627,0.0000909107,0.00001594507,0.000001855091,0.00003643884,0.00001341772,0.00006147303,0.9982096,0.000669715,0.00003347319,0.0008171698],"study_design_scores_gemma":[0.00001568037,0.00002940182,0.00329595,0.000005668967,0.000006947234,0.0002934608,0.0000276611,0.001167127,0.9932536,0.0002080727,0.001691376,0.000005062392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.89441,0.004492019,0.08576433,0.001078866,0.00017528,0.0001526494,0.001223724,0.0005309262,0.01217215],"genre_scores_gemma":[0.9413626,0.001931514,0.04167406,0.0002231123,0.00003891231,0.0001661241,0.0007381323,0.0003838127,0.01348173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002659391,"threshold_uncertainty_score":0.007391989,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2152695624","doi":"10.1186/1471-2148-10-374","title":"Conservation, loss, and redeployment of Wnt ligands in protostomes: implications for understanding the evolution of segment formation","year":2010,"lang":"en","type":"article","venue":"BMC Evolutionary Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Los Alamos National Laboratory; Lawrence Berkeley National Laboratory; Lawrence Livermore National Laboratory; Biological and Environmental Research; National Cancer Institute; Office of Science; Centre National de la Recherche Scientifique; Agence Nationale de la Recherche; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Department of Energy; European Commission; Joint Genome Institute; Lilly Endowment; National Institutes of Health; Terry Fox Foundation; Deutsche Forschungsgemeinschaft; Eli Lilly and Company; National Science Foundation","keywords":"Biology; Wnt signaling pathway; Evolutionary biology; Genetics; Gene; Annelid; Zoology","authors":[{"name":"Ralf Janßen","is_ca":false},{"name":"Martine Le Gouar","is_ca":false},{"name":"Matthias Pechmann","is_ca":false},{"name":"Francis Poulin","is_ca":false},{"name":"Renata Bolognesi","is_ca":false},{"name":"Evelyn E. Schwager","is_ca":false},{"name":"Corinna Hopfen","is_ca":false},{"name":"John K. Colbourne","is_ca":false},{"name":"Graham E. Budd","is_ca":false},{"name":"Susan J. Brown","is_ca":false},{"name":"Nikola-Michael Prpíc","is_ca":false},{"name":"Carolin Kosiol","is_ca":false},{"name":"Michel Vervoort","is_ca":false},{"name":"Wim G.M. Damen","is_ca":false},{"name":"Guillaume Balavoine","is_ca":false},{"name":"Alistair P. McGregor","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02247016794489827,"gpt":0.2749408588409123,"spread":0.2524706908960141,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002043646,0.0001415019,0.0002489281,0.0005589701,0.0002804486,0.0004315745,0.0002107456,0.0004673091,0.0006771781],"category_scores_gemma":[0.0002337297,0.0001335404,0.0001805335,0.0004152429,0.0005267572,0.0005142015,0.000300978,0.0003337742,0.0001740614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003584985,"about_ca_system_score_gemma":0.000184174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008548932,"about_ca_topic_score_gemma":0.001941131,"domain_scores_codex":[0.9999039,0.000008204117,0.000008444749,0.00004219163,0.00001882329,0.00001841947],"domain_scores_gemma":[0.99967,0.00006270121,0.0001606825,0.00002798027,0.00002773398,0.00005091877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000243297,0.00001051524,0.05404279,0.0001006021,0.00001616309,0.0001338784,0.0001987964,0.0001474254,0.9383918,0.000303087,0.00002585484,0.00638593],"study_design_scores_gemma":[0.000008545678,0.0001118652,0.9560058,0.00002718752,0.00003499463,0.001031535,0.0003230905,0.0006139919,0.03909799,0.0003181514,0.002416287,0.00001060286],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962597,0.001987866,0.0009428965,0.00005398931,0.000002397593,0.000005451328,0.0002687906,0.00001211934,0.0004667424],"genre_scores_gemma":[0.9965425,0.001112472,0.001344925,0.00003962187,0.000005547003,0.000008133335,0.000408436,0.000005686643,0.0005327404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008548932,"threshold_uncertainty_score":0.002601027,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2018339347","doi":"10.1016/s1534-5807(04)00098-x","title":"High Commitment of Embryonic Keratinocytes to Terminal Differentiation through a Notch1-caspase 3 Regulatory Mechanism","year":2004,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Cancer Institute; Ministry of Education, Culture, Sports, Science and Technology; Japan Society for the Promotion of Science; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Biology; Embryonic stem cell; Cell biology; Keratinocyte; Cellular differentiation; Morphogenesis; Notch signaling pathway; Epidermis (zoology); Signal transduction; Cell culture; Anatomy; Genetics","authors":[{"name":"Ryuhei Okuyama","is_ca":false},{"name":"Bach-Cuc Nguyen","is_ca":false},{"name":"Claudio Talora","is_ca":false},{"name":"Eisaku Ogawa","is_ca":false},{"name":"Alice Tommasi di Vignano","is_ca":false},{"name":"Maria Lioumi","is_ca":false},{"name":"Giovanna Chiorino","is_ca":false},{"name":"Hachiro Tagami","is_ca":false},{"name":"Minna Woo","is_ca":true},{"name":"G. Paolo Dotto","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00800373067113496,"gpt":0.2171462744940267,"spread":0.2091425438228917,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001847708,0.0001394362,0.0002154226,0.0003595047,0.0001885862,0.0005745345,0.0002160501,0.0002212663,0.00165275],"category_scores_gemma":[0.0001615552,0.0001575831,0.0002295365,0.0002030526,0.0001766538,0.0002696315,0.0004334939,0.0007857554,0.0006911189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003970804,"about_ca_system_score_gemma":0.000235039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003962823,"about_ca_topic_score_gemma":0.0007171486,"domain_scores_codex":[0.9997798,0.00002520799,0.00002372412,0.00003732242,0.00008222143,0.00005179393],"domain_scores_gemma":[0.9997482,0.00003379658,0.00003505806,0.00006941111,0.00005247688,0.0000611248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006393161,0.000007269227,0.0004193097,0.00001123543,0.000002690245,0.00004041478,0.000008333001,0.00002180249,0.9982002,0.0001459484,0.00003178319,0.001047094],"study_design_scores_gemma":[0.000008145156,0.00005377726,0.0195959,0.000005423526,0.00001161942,0.0004126672,0.0000455864,0.000320283,0.9775276,0.0001510885,0.001863416,0.000004465621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987397,0.001895404,0.006120832,0.0001443708,0.00003220322,0.00002756424,0.0004589657,0.0001875996,0.003736047],"genre_scores_gemma":[0.9933845,0.0004618446,0.002012483,0.00005098273,0.0000082383,0.00002232174,0.000330418,0.00003376215,0.003695317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00165275,"threshold_uncertainty_score":0.005528986,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2008711375","doi":"10.1101/gr.716103","title":"Regulatory Roles of Conserved Intergenic Domains in Vertebrate <i>Dlx</i> Bigene Clusters","year":2003,"lang":"en","type":"article","venue":"Genome Research","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":182,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"Université Libanaise; Canadian Institutes of Health Research; March of Dimes Foundation","keywords":"Biology; Genetics; Intergenic region; Enhancer; DLX5; Homeobox; Evolutionary biology; Regulatory sequence; Zebrafish; Vertebrate; Conserved sequence; Chordate; Gene; Genome; Regulation of gene expression; Transcription factor; Peptide sequence","authors":[{"name":"Noël Ghanem","is_ca":true},{"name":"Olga Jarinova","is_ca":true},{"name":"Angel Amores","is_ca":true},{"name":"Qiaoming Long","is_ca":true},{"name":"Gary Hatch","is_ca":true},{"name":"Byung Keon Park","is_ca":true},{"name":"John L.R. Rubenstein","is_ca":true},{"name":"Marc Ekker","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02546888739867591,"gpt":0.3043488715129963,"spread":0.2788799841143204,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201811,0.0002327907,0.0002085356,0.0004976983,0.0002626509,0.000318329,0.0002637282,0.0002009114,0.0007716116],"category_scores_gemma":[0.0002047916,0.0001909593,0.000234587,0.0002256809,0.0002567495,0.0002221898,0.0004886804,0.000330501,0.000274706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00030191,"about_ca_system_score_gemma":0.0001479681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008960903,"about_ca_topic_score_gemma":0.001838927,"domain_scores_codex":[0.9997781,0.00002298522,0.00001190822,0.0001075153,0.00004020072,0.00003936722],"domain_scores_gemma":[0.9998003,0.00004187484,0.0000631211,0.00001669181,0.00001773016,0.00006029402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002131301,0.00001568198,0.004610241,0.00005003565,0.00001015851,0.0001451033,0.0001284934,0.0001521694,0.9910472,0.0003549458,0.00003394944,0.00323886],"study_design_scores_gemma":[0.00008388887,0.0003762971,0.5504475,0.00007704114,0.000100035,0.001335826,0.0004845526,0.00394096,0.4329263,0.0009281579,0.009250359,0.00004919294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956868,0.001105471,0.001771984,0.00002179687,0.000006446676,0.000008224841,0.000147801,0.00003866114,0.001212771],"genre_scores_gemma":[0.9970137,0.0001955973,0.001328084,0.0000391039,0.000004268189,0.00001090249,0.0005013305,0.0000128051,0.0008942623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008960903,"threshold_uncertainty_score":0.002581298,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2152302317","doi":"10.2353/ajpath.2006.050416","title":"Overexpression of Activated Murine Notch1 and Notch3 in Transgenic Mice Blocks Mammary Gland Development and Induces Mammary Tumors","year":2006,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Mammary gland; Genetically modified mouse; Transgene; Mammary tumor; Cancer research; Cell biology; Biology; Internal medicine; Medicine; Gene; Cancer; Breast cancer; Genetics","authors":[{"name":"Chunyan Hu","is_ca":true},{"name":"Anne Diévart","is_ca":false},{"name":"Mathieu Lupien","is_ca":false},{"name":"Ézéquiel Calvo","is_ca":false},{"name":"Gilles Tremblay","is_ca":true},{"name":"Paul Jolicoeur","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004152489704758382,"gpt":0.2150726977107213,"spread":0.2109202080059629,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004316527,0.001059686,0.0005482937,0.001862785,0.0004545433,0.0008703811,0.0009522258,0.00102329,0.003635101],"category_scores_gemma":[0.000302883,0.0008067579,0.0006962642,0.0006295315,0.0009922133,0.000528188,0.0004893664,0.002075477,0.001431053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001243627,"about_ca_system_score_gemma":0.0007986074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00175416,"about_ca_topic_score_gemma":0.004095099,"domain_scores_codex":[0.9992481,0.00009294954,0.00008217394,0.0001468526,0.0002092364,0.0002206429],"domain_scores_gemma":[0.9987954,0.000222521,0.0004365925,0.0001250745,0.00004740656,0.0003730154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002184239,0.00005851335,0.0001045793,0.00001881389,0.000007826991,0.00005861014,0.00001333386,0.00007903187,0.9986899,0.0002995417,0.0000480412,0.0004032559],"study_design_scores_gemma":[0.00005370343,0.0001396997,0.0009219163,0.000006610251,0.00002519258,0.0002234969,0.0000274603,0.0008730722,0.996614,0.00008813995,0.001020705,0.00000607852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838346,0.001706561,0.006610846,0.0004746509,0.0001503113,0.0001219487,0.002279234,0.00088945,0.003932192],"genre_scores_gemma":[0.980545,0.001107364,0.004372364,0.0001535187,0.00005829716,0.0001347322,0.00153817,0.0003544915,0.01173605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003635101,"threshold_uncertainty_score":0.01216066,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2073274309","doi":"10.1210/en.2002-0216","title":"Six Novel Gonadotropin-Releasing Hormones Are Encoded as Triplets on Each of Two Genes in the Protochordate,<i>Ciona intestinalis</i>","year":2003,"lang":"en","type":"article","venue":"Endocrinology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Victoria","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; China Scholarship Council; National Institutes of Health; University of Victoria","keywords":"Ciona intestinalis; Tunicate; Ciona; Biology; Chordate; Gene; Intron; In silico; Gonadotropin-releasing hormone; Genetics; Minigene; Cell biology; Internal medicine; Vertebrate; Endocrinology; Exon; Hormone; Alternative splicing; Luteinizing hormone","authors":[{"name":"Bruce A. Adams","is_ca":true},{"name":"Javier A. Tello","is_ca":true},{"name":"Judit Érchegyi","is_ca":false},{"name":"C. Warby","is_ca":true},{"name":"Doley J. Hong","is_ca":false},{"name":"Karen Akinsanya","is_ca":false},{"name":"G. O. Mackie","is_ca":true},{"name":"Wylie Vale","is_ca":false},{"name":"Jean Rivier","is_ca":false},{"name":"Nancy M. Sherwood","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01938681434981864,"gpt":0.2856500084096846,"spread":0.2662631940598659,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007504441,0.0003585264,0.0001741701,0.000236566,0.0002234515,0.0002873503,0.000245918,0.0002686298,0.0009158969],"category_scores_gemma":[0.0001531329,0.0001709838,0.0003322493,0.0001773519,0.0002985655,0.0001632121,0.0001982037,0.0003844218,0.0002754781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002675027,"about_ca_system_score_gemma":0.0002994316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009477485,"about_ca_topic_score_gemma":0.001554417,"domain_scores_codex":[0.9999062,0.000004448171,0.000006524604,0.00003391506,0.00003208538,0.00001683017],"domain_scores_gemma":[0.9998717,0.00001946557,0.00004514801,0.000009886632,0.00001599414,0.0000377446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001340347,0.00001745873,0.00296572,0.00006589357,0.00000679917,0.0002780511,0.0000374906,0.0000884047,0.9915297,0.0001696363,0.00005389907,0.004652864],"study_design_scores_gemma":[0.0001112787,0.0010503,0.3077756,0.0000845854,0.0001657404,0.003641811,0.0002873303,0.003103737,0.6563483,0.0004481246,0.02691731,0.00006602034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941175,0.0006953257,0.002526138,0.00007147477,0.00005312689,0.00004449925,0.00060998,0.00006828787,0.001813799],"genre_scores_gemma":[0.9816983,0.00049343,0.01141134,0.0001329812,0.00002871124,0.00005012359,0.002734617,0.00002400575,0.003426519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009477485,"threshold_uncertainty_score":0.003063917,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}