{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":4101,"total_is_capped":false,"direct_labels_cover":8,"predictions_cover":4101,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"f12170854b05","filters":{"topic":"Epigenetics and DNA Methylation"}},"results":[{"id":"W2076154138","doi":"10.1038/nature14248","title":"Integrative analysis of 111 reference human epigenomes","year":2015,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7110,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Simon Fraser University; University of British Columbia; Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Common Fund; National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Deafness and Other Communication Disorders; National Institute on Drug Abuse; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Institute on Aging; Tsinghua National Laboratory for Information Science and Technology; National Center for Advancing Translational Sciences; National Human Genome Research Institute; Tsinghua University; National Natural Science Foundation of China; National Institutes of Health; National Science Foundation; Washington University in St. Louis; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Massachusetts General Hospital; Howard Hughes Medical Institute","keywords":"Epigenomics; DNA methylation; Computational biology; Biology; Human genome; Genetics; Epigenome; Chromatin; Genome; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.02391063745499477,"gpt":0.3307579090249536,"spread":0.3068472715699588,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000154289,0.00007712889,0.0001387569,0.0000890908,0.00002192027,0.000006434847,0.0001193205,0.0005274245,0.00001365541],"category_scores_gemma":[0.00009553396,0.00006142269,0.00007382799,0.0002634433,0.00003464847,0.000001441735,0.00004050631,0.0002680354,0.000001531503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009007427,"about_ca_system_score_gemma":0.00003815666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002174122,"about_ca_topic_score_gemma":0.0002557041,"domain_scores_codex":[0.9994711,0.00004071129,0.000122068,0.0001697656,0.0001155384,0.00008079295],"domain_scores_gemma":[0.9993855,0.000006313109,0.00007912346,0.0002243146,0.0002531841,0.00005160884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004971063,0.00006358589,0.04000991,0.000006598205,0.0006351972,0.000001062436,0.0003610896,0.0003509286,0.9528093,0.002473089,0.001393805,0.001845768],"study_design_scores_gemma":[0.0003672725,0.0005076217,0.05918531,0.00000744079,0.0003572023,2.32314e-7,0.0003470963,0.00007641126,0.8650302,0.001668649,0.07222164,0.0002309662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831893,0.005690446,0.0005716069,0.00004617797,0.00006964136,0.00005046007,0.00002896136,0.000004090432,0.01034932],"genre_scores_gemma":[0.9979972,0.0001030448,0.0005653528,0.00005633297,0.00006400581,0.000002631334,0.0004118019,0.000005606458,0.0007939781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08777911,"threshold_uncertainty_score":0.4067981,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2060608189","doi":"10.1038/nature09784","title":"The Polycomb complex PRC2 and its mark in life","year":2011,"lang":"en","type":"review","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3366,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; Institute of Cancer Research; Howard Hughes Medical Institute","keywords":"PRC2; Polycomb-group proteins; Chromatin; Histone H3; Cell biology; Biology; Histone; Genetics; Gene; Gene expression; Repressor","retraction":null,"screen_n_in":null,"score":{"opus":0.0359584793311401,"gpt":0.3292322941449638,"spread":0.2932738148138237,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002338252,0.0001973953,0.0003241668,0.00003745806,0.00006382502,0.0000255458,0.000220328,0.001806338,0.000007955555],"category_scores_gemma":[0.0001728652,0.0001276713,0.0001069136,0.00008482015,0.00003007341,9.030476e-7,0.0001272685,0.0009233691,0.000006106744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007771244,"about_ca_system_score_gemma":0.00009755497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003150492,"about_ca_topic_score_gemma":0.00003851955,"domain_scores_codex":[0.9991287,0.0001234109,0.0002248133,0.0002799761,0.00007317672,0.0001699335],"domain_scores_gemma":[0.9994686,0.00003479106,0.0001280676,0.000267975,0.00003827311,0.0000622735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001961072,0.0000295559,0.00005285229,0.001384054,0.0001019952,0.000002809634,0.00001639366,1.552373e-7,0.0004612411,0.001062178,0.002931425,0.9939377],"study_design_scores_gemma":[0.00008468117,0.0000355896,0.0002278017,0.000247813,0.00003301588,0.000002638748,0.000002129413,0.000001724737,0.00008526747,0.00007602166,0.9990515,0.0001518242],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002569939,0.9976448,0.000002396682,0.00004804913,0.0001893556,0.0003090562,0.00002537529,0.000003720654,0.001520252],"genre_scores_gemma":[0.001450455,0.997378,0.00004997542,0.0001009571,0.0002297688,0.00002290584,0.0001904935,0.00002828257,0.0005491432],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9961201,"threshold_uncertainty_score":0.9994895,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2084160423","doi":"10.1038/nbt1010-1045","title":"The NIH Roadmap Epigenomics Mapping Consortium","year":2010,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2046,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"National Human Genome Research Institute","keywords":"Epigenomics; Computational biology; Ex vivo; Human disease; Biology; Genetics; In vivo; Gene; DNA methylation; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.00389924591743176,"gpt":0.2358489717402764,"spread":0.2319497258228446,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003190333,0.0001411839,0.0001053369,0.00005971214,0.0002462821,0.00003044879,0.0004152298,0.001772398,0.000008746417],"category_scores_gemma":[0.0004314282,0.0001074501,0.00007112233,0.0001286509,0.0002779622,0.000001522509,0.0001716902,0.0009599407,0.00001956267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008135509,"about_ca_system_score_gemma":0.00006293757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005595435,"about_ca_topic_score_gemma":0.0001847682,"domain_scores_codex":[0.9990537,0.00002815702,0.0001931596,0.0003416403,0.00008521611,0.0002981502],"domain_scores_gemma":[0.9990534,0.00003047055,0.0001039007,0.0006827354,0.00008258773,0.00004696463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001418264,0.00001184197,0.0008976039,0.000002054168,0.00002209473,0.000001242723,0.000006446074,0.000002306301,0.9676455,0.007676712,0.0005231262,0.0231969],"study_design_scores_gemma":[0.0001000533,0.00004043857,0.001595011,8.342586e-7,0.000003401698,0.000005462201,0.00001964504,0.00001830722,0.5114151,0.001112424,0.4856024,0.00008701816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983542,0.006846772,0.00165546,0.004617197,0.001435455,0.0001874316,0.000009237638,0.00005384266,0.001652628],"genre_scores_gemma":[0.9951677,0.00133845,0.002291728,0.0002414084,0.0003688736,0.00001271077,0.00003703617,0.00002159579,0.0005205245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4850792,"threshold_uncertainty_score":0.9995235,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2055237453","doi":"10.1038/nrg3142","title":"Epigenetics and the environment: emerging patterns and implications","year":2012,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1926,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Ligue Contre le Cancer; Agence Nationale de la Recherche","keywords":"Epigenetics; Biology; DNA methylation; Epigenesis; Chromatin; Disease; Phenotype; Epigenomics; Genetics; Evolutionary biology; Computational biology; Ecology; Gene expression; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.03102289477500049,"gpt":0.3299062737325293,"spread":0.2988833789575288,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008480819,0.0005252601,0.001040224,0.00006304583,0.0001941411,0.00006127679,0.0003264249,0.0009200927,0.00001511266],"category_scores_gemma":[0.00008201497,0.0003412206,0.0003226776,0.000102563,0.000207587,0.000002500648,0.0004097892,0.0005906001,0.00001323914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001745425,"about_ca_system_score_gemma":0.00004289987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001978299,"about_ca_topic_score_gemma":0.000007971184,"domain_scores_codex":[0.9976822,0.0004853535,0.0007392014,0.000593952,0.0001485031,0.0003508516],"domain_scores_gemma":[0.9982376,0.00008437791,0.0005240008,0.0009542817,0.00003540671,0.0001643972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001485343,0.00001387096,0.0001653363,0.002249498,0.00007671311,1.350145e-7,0.00002213218,6.946543e-7,0.00005949294,0.0001546406,0.00005070841,0.9972053],"study_design_scores_gemma":[0.0002075648,0.00003248771,0.0001995641,0.0005365163,0.001211586,0.00001490587,0.000003213224,0.000002752956,0.0000532478,0.0001090773,0.997254,0.0003751591],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009599248,0.9969112,0.000949882,0.00008675519,0.0001736254,0.001502149,0.00008423735,0.00000580813,0.0001903405],"genre_scores_gemma":[0.0003238758,0.9970618,0.001063164,0.0001148578,0.0005848332,0.000223186,0.0003760491,0.00008146693,0.000170741],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9972032,"threshold_uncertainty_score":0.999904,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2065498897","doi":"10.1038/nature09165","title":"Conserved role of intragenic DNA methylation in regulating alternative promoters","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1765,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Douglas Mental Health University Institute; University of British Columbia; BC Cancer Agency","funders":"National Institute of Environmental Health Sciences; Howard Hughes Medical Institute","keywords":"Promoter; DNA methylation; Biology; Epigenetics of physical exercise; CpG site; Methylation; Genetics; Gene; Differentially methylated regions; Molecular biology; RNA-Directed DNA Methylation; Transcription (linguistics); Regulation of gene expression; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.004945052448378222,"gpt":0.2580452265444578,"spread":0.2531001740960796,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000254473,0.00007966658,0.00009126442,0.00005251561,0.00001890067,0.000007183927,0.00009932433,0.000666047,0.00001214686],"category_scores_gemma":[0.0002229306,0.00007706966,0.00004219389,0.00009340535,0.00003413806,0.000003420346,0.00003549078,0.0005565417,6.773644e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005491016,"about_ca_system_score_gemma":0.00003292723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002149794,"about_ca_topic_score_gemma":0.00020157,"domain_scores_codex":[0.999391,0.00004891978,0.0001703459,0.000186244,0.00009958279,0.0001039743],"domain_scores_gemma":[0.9995728,0.00001708378,0.0001107378,0.0001826991,0.0000894498,0.00002726724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002565296,0.00002063456,0.006709323,0.000006699298,0.00001154551,3.176329e-7,0.0001087213,0.0000793197,0.9844269,0.000257993,0.000005488846,0.008347435],"study_design_scores_gemma":[0.0003016699,0.00005958125,0.02649705,0.000007647986,0.000004882821,6.511991e-7,0.00003215515,0.0005395573,0.9688125,0.002599639,0.001064606,0.00008002143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977852,0.0008687112,0.0001025648,0.00009135862,0.0001549833,0.0001413517,0.000006979935,0.000004019608,0.0008448645],"genre_scores_gemma":[0.9976887,0.00002920025,0.002006631,0.00002965371,0.0001133662,0.000005428204,0.00006947613,0.00001080562,0.00004680756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01978773,"threshold_uncertainty_score":0.5137164,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101259235","doi":"10.1038/ng1598","title":"Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells","year":2005,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1754,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; DNA methylation; CpG site; Epigenetics; Methylation; Promoter; Differentially methylated regions; Epigenetics of physical exercise; Genetics; Illumina Methylation Assay; RNA-Directed DNA Methylation; Gene; Human genome; Molecular biology; Epigenomics; Chromosome; Genome; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.01811698372051576,"gpt":0.3116644724781628,"spread":0.2935474887576471,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001479886,0.000164488,0.0001918992,0.0001199104,0.00005284941,0.00003051243,0.00009000269,0.0004130122,0.00001500637],"category_scores_gemma":[0.00001648992,0.0001593799,0.00005206966,0.0001102312,0.00008310752,0.000007353475,0.00005096247,0.0001891785,4.270697e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009689982,"about_ca_system_score_gemma":0.00001684457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003905194,"about_ca_topic_score_gemma":0.0001565478,"domain_scores_codex":[0.9989514,0.00005889207,0.000323857,0.0003135965,0.0001734955,0.0001787652],"domain_scores_gemma":[0.9995492,0.00001807209,0.0001028259,0.00018688,0.00008016353,0.00006293765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002447806,0.00005437029,0.01841166,0.00003749377,0.00002452458,5.839166e-7,0.0001469694,0.0001009147,0.9737988,0.000007581977,0.00001643216,0.007376246],"study_design_scores_gemma":[0.0005490683,0.000155347,0.1737994,0.00001037989,0.00002722454,8.136382e-7,0.0000168845,0.0001285654,0.8236535,0.0001178714,0.001400542,0.0001404855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817114,0.01699224,0.0008411178,0.00004657823,0.0000601012,0.0002050258,0.00002149066,0.000004544912,0.0001174391],"genre_scores_gemma":[0.9945923,0.003288373,0.001698781,0.0000206058,0.0001823877,0.000005020789,0.0001539934,0.00001623549,0.00004230031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1553877,"threshold_uncertainty_score":0.6499322,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1975528145","doi":"10.4161/epi.23470","title":"Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray","year":2013,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1719,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; Toronto General Hospital; University Health Network; University of Toronto; SickKids Foundation; Hospital for Sick Children; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; DNA methylation; Illumina Methylation Assay; Genetics; Methylation; Epigenetics; Microarray; DNA microarray; Differentially methylated regions; Computational biology; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.01179436864305644,"gpt":0.2683694433457032,"spread":0.2565750747026468,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002995607,0.0001552099,0.0001501819,0.00006516657,0.00006770122,0.00008166546,0.0001924159,0.0001523505,0.000009971319],"category_scores_gemma":[0.00009704529,0.0001220742,0.00005490016,0.0001222014,0.0002685336,0.00001447916,0.00006803503,0.0001030969,0.000004557618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007274769,"about_ca_system_score_gemma":0.00004053763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001677,"about_ca_topic_score_gemma":0.00009797767,"domain_scores_codex":[0.9989166,0.0001144613,0.0003306913,0.0002795893,0.0001533567,0.0002052845],"domain_scores_gemma":[0.9992778,0.00005791222,0.0001467543,0.0003627666,0.0001221309,0.00003258222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001275166,0.000065917,0.0986236,0.00001990905,0.00001629891,4.331825e-7,0.0006272668,0.0001035192,0.8984492,0.0001581156,0.0000280935,0.001894835],"study_design_scores_gemma":[0.0002512081,0.000177213,0.4049841,0.00000892269,0.000009174055,0.00000127568,0.0001761088,0.00003095814,0.5917637,0.00138733,0.001083629,0.0001262975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927337,0.004533773,0.001077807,0.0001573508,0.00007583122,0.0003969884,0.00001431295,0.00000316738,0.001007048],"genre_scores_gemma":[0.9977431,0.0009118897,0.0007267701,0.00007471302,0.0001112436,0.00004319128,0.00005149608,0.00001888876,0.0003187053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3066855,"threshold_uncertainty_score":0.497804,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2024373518","doi":"10.1038/ng.518","title":"Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin","year":2010,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1650,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"EZH2; Histone H3; Biology; PRC2; Histone methyltransferase; Germinal center; Cancer research; Diffuse large B-cell lymphoma; Histone methylation; Histone; Molecular biology; B cell; Genetics; DNA methylation; Gene; Gene expression; Antibody","retraction":null,"screen_n_in":null,"score":{"opus":0.004996011660939228,"gpt":0.2618415122544837,"spread":0.2568455005935444,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001725848,0.0001582436,0.0001596915,0.00008963099,0.00004563736,0.00002056388,0.0001338505,0.0004042915,0.000009187689],"category_scores_gemma":[0.00005269346,0.0001573232,0.00006082973,0.00009457129,0.00005152071,0.000003542257,0.00009835532,0.0002382093,0.000001967247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007473089,"about_ca_system_score_gemma":0.00004815231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005052938,"about_ca_topic_score_gemma":0.0001356682,"domain_scores_codex":[0.9990245,0.00003716322,0.0002745363,0.0002872278,0.0001449874,0.0002315719],"domain_scores_gemma":[0.9993844,0.00001778431,0.0001093374,0.0003383971,0.00007176414,0.00007833684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001498823,0.0003486444,0.06059377,0.00005968837,0.00001365789,0.000005330352,0.0001127712,0.00003203455,0.9374065,0.00004524226,0.00001134276,0.001356076],"study_design_scores_gemma":[0.002812461,0.0001241515,0.03930787,0.00001722028,0.0000289513,0.00001070039,0.00004319078,0.000993592,0.9436722,0.0004509124,0.012302,0.0002366871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944406,0.004105594,0.0005822096,0.00003344991,0.0002536744,0.0001865651,0.00003899186,0.000005809367,0.000353098],"genre_scores_gemma":[0.9941621,0.0006549644,0.004766033,0.00005506491,0.0001231574,0.00001125649,0.0001020942,0.00002658737,0.00009872019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0212859,"threshold_uncertainty_score":0.6415454,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1905278501","doi":"10.1016/j.cell.2015.07.056","title":"DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1524,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital; University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute","keywords":"Biology; IRF7; Cancer research; Gene knockdown; Colorectal cancer; RNA silencing; Small interfering RNA; Virology; RNA; Druggability; Transfection; Innate immune system; RNA interference; Cancer; Genetics; Cell culture; Gene; Immune system","retraction":null,"screen_n_in":null,"score":{"opus":0.02669207330958193,"gpt":0.2508067011173336,"spread":0.2241146278077516,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002400935,0.0002031116,0.0001658607,0.00002719676,0.00009158838,0.00003402027,0.0001758098,0.0002225629,0.00003605415],"category_scores_gemma":[0.00002218789,0.0002138455,0.00008028749,0.00007066002,0.00004347302,0.000006059865,0.00005196363,0.0001252459,0.00001436335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004298616,"about_ca_system_score_gemma":0.0001018001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001902919,"about_ca_topic_score_gemma":0.00001526807,"domain_scores_codex":[0.9987103,0.00009888421,0.0002512968,0.000401178,0.0001812165,0.0003571492],"domain_scores_gemma":[0.9994204,0.00001029733,0.0001139401,0.0001791231,0.00008210617,0.0001941516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003085735,0.00007742939,0.001051642,0.00001462836,0.00002279197,0.00000209602,0.0003366977,0.0003132532,0.9881871,2.991726e-7,0.0093274,0.0006357942],"study_design_scores_gemma":[0.0006969494,0.0002187348,0.0000668581,0.000005190867,0.00002069871,7.069747e-7,0.00008494067,0.0001777917,0.95595,0.0000273583,0.04250167,0.0002491621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98182,0.01211506,0.001672324,0.00002833387,0.0005113049,0.0002087023,0.0001636199,0.00001615054,0.003464541],"genre_scores_gemma":[0.9970486,0.0003990018,0.0008085211,0.0001415776,0.0002081784,0.00002582613,0.0004187869,0.0000448587,0.0009046947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03317427,"threshold_uncertainty_score":0.8720368,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2092015913","doi":"10.1038/nature01572","title":"Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells","year":2003,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1457,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hôpital Maisonneuve-Rosemont; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Leukemia and Lymphoma Society","keywords":"Stem cell; Progenitor cell; Biology; Cancer research; Cell biology; Population; Cancer stem cell; BMI1; Immunology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.009255410419489126,"gpt":0.2359062615112588,"spread":0.2266508510917697,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315588,0.0000704546,0.00006689232,0.00001090534,0.00004535769,0.000008212094,0.00005812841,0.0003777191,0.000002805956],"category_scores_gemma":[0.00002824933,0.00004700311,0.00002822416,0.00003698354,0.00005766107,0.000001807228,0.00001968173,0.0002357344,4.209155e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002711731,"about_ca_system_score_gemma":0.00002403184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002173644,"about_ca_topic_score_gemma":0.00001733849,"domain_scores_codex":[0.9995775,0.00006121251,0.00008791136,0.0001243166,0.00006745244,0.00008166311],"domain_scores_gemma":[0.9997004,0.00001340148,0.00005096148,0.0001387749,0.00007373369,0.00002275732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000116371,0.000009995067,0.00655415,0.00001239201,0.00001186003,2.311366e-7,0.00007593799,0.00002019265,0.9922259,0.000223377,0.0001236563,0.0007306784],"study_design_scores_gemma":[0.0001459498,0.00007938314,0.002329886,0.000003615115,0.000008156052,0.000002694098,0.00003534132,0.00001938648,0.9870064,0.0001270291,0.01018357,0.00005861347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995243,0.00358148,0.0001457468,0.00003747145,0.0000956822,0.0001131915,0.00001164229,0.000001851118,0.0007699585],"genre_scores_gemma":[0.9990541,0.0001961561,0.0003166157,0.00009565872,0.00005534396,0.000004516278,0.000004032973,0.000005795601,0.0002677896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01005992,"threshold_uncertainty_score":0.2913316,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2591367881","doi":"10.1038/nmeth.4184","title":"Detecting DNA cytosine methylation using nanopore sequencing","year":2017,"lang":"en","type":"article","venue":"Nature Methods","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1257,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Minion; Nanopore sequencing; Nanopore; 5-Methylcytosine; DNA sequencer; DNA methylation; Cytosine; DNA; Computational biology; DNA sequencing; Hidden Markov model; Sequencing by ligation; genomic DNA; Human genome; Computer science; Biology; Genetics; Genome; Genomic library; Nanotechnology; Gene; Base sequence; Materials science; Artificial intelligence","retraction":null,"screen_n_in":null,"score":{"opus":0.04533398034043244,"gpt":0.41577286745941,"spread":0.3704388871189775,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001647982,0.0001720335,0.0001725713,0.00006118816,0.0005822048,0.0001125895,0.0002727402,0.0005739398,0.000009552516],"category_scores_gemma":[0.001961928,0.0001646009,0.0001047527,0.00006336345,0.0000594132,0.00001168212,0.0001607203,0.0003272513,0.000001176453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004685235,"about_ca_system_score_gemma":0.00008351327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000359331,"about_ca_topic_score_gemma":0.00002529331,"domain_scores_codex":[0.9987282,0.000270593,0.0002207942,0.0003926392,0.0001504229,0.0002374126],"domain_scores_gemma":[0.9986717,0.00004497364,0.0003100224,0.0007312885,0.0001720603,0.00006991579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000151932,0.00000500712,0.001333448,0.00001137295,0.00002408918,0.000001548862,0.00003109981,0.0001903566,0.9462127,0.0000568544,0.000005521733,0.05211282],"study_design_scores_gemma":[0.0002320905,0.00005627139,0.002880396,0.00001788238,0.0000330576,0.000005599891,0.00002712997,0.002319819,0.9870489,0.001056779,0.006120665,0.0002014648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.758453,0.003296594,0.235416,0.00006392464,0.0005964694,0.0001273858,0.000003920445,0.00001590838,0.002026799],"genre_scores_gemma":[0.6688136,0.00005669969,0.3304488,0.00005157686,0.0004530618,0.000003069985,0.00001949651,0.0000246149,0.0001290397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09503283,"threshold_uncertainty_score":0.6712229,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2028630156","doi":"10.1242/dev.033183","title":"The maternal-to-zygotic transition: a play in two acts","year":2009,"lang":"en","type":"review","venue":"Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1249,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Biology; Maternal to zygotic transition; Zygote; Embryo; Gene; Evolutionary biology; Genome; Genetics; Embryogenesis; Cell biology","retraction":null,"screen_n_in":null,"score":{"opus":0.02587045014523557,"gpt":0.3360144041020196,"spread":0.310143953956784,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003460988,0.000240488,0.0003607619,0.0000724894,0.0000865299,0.00004999975,0.0002357163,0.0001295964,0.000006163486],"category_scores_gemma":[0.0000210537,0.0001704075,0.00009847347,0.0001315847,0.00001309949,0.000001003832,0.0000508999,0.0001118312,0.00006300369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006093239,"about_ca_system_score_gemma":0.000301442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003760575,"about_ca_topic_score_gemma":0.0001236613,"domain_scores_codex":[0.9987351,0.00008991171,0.0004415246,0.0003238807,0.000151585,0.000257984],"domain_scores_gemma":[0.9995205,0.0000148354,0.00009716746,0.0002589474,0.0000308222,0.00007772793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005785463,0.00001684126,0.000004952197,0.0002351939,0.00003576594,0.000007076522,0.00008138901,0.00001985944,0.00009959414,0.00001783731,0.00007061767,0.9994051],"study_design_scores_gemma":[0.0001238708,0.00003220187,0.0002941131,0.0009460351,0.00002290212,0.000005141517,0.000002912581,7.444957e-7,0.001311735,0.00002322979,0.9970146,0.0002225234],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001406512,0.9967173,0.0004021878,0.00006206874,0.0001751868,0.0005178382,0.000004779394,0.000005782774,0.0007083787],"genre_scores_gemma":[0.001190593,0.9965398,0.001180092,0.00008806322,0.0001378805,0.0001072604,0.0001933742,0.00002580581,0.000537103],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9991826,"threshold_uncertainty_score":0.6949016,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2055986128","doi":"10.1016/j.ccr.2014.07.028","title":"Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer","year":2014,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1246,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Institutes of Health; National Cancer Institute; Princess Margaret Cancer Foundation","keywords":"DNA methylation; Methylation; Biology; Gene; Promoter; Gene expression; Epigenetics; Carcinogenesis; Regulation of gene expression; Epigenetics of physical exercise; RNA-Directed DNA Methylation; Demethylation; Cancer research; Genetics; Molecular biology","retraction":null,"screen_n_in":null,"score":{"opus":0.01302609287177919,"gpt":0.278225427895976,"spread":0.2651993350241968,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001470804,0.0001336586,0.0001238688,0.00002961944,0.0000467718,0.00001786538,0.00007521299,0.000130035,0.00008819519],"category_scores_gemma":[0.000006005758,0.000123699,0.00003286562,0.00005271712,0.00002743946,0.000004513333,0.00004491835,0.00005952027,0.000001178203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003642028,"about_ca_system_score_gemma":0.00005214358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005715423,"about_ca_topic_score_gemma":0.0003526376,"domain_scores_codex":[0.9991433,0.00007356785,0.0001612577,0.0003394706,0.00009284064,0.0001895551],"domain_scores_gemma":[0.999586,0.000009060773,0.00007755599,0.0002113916,0.00004838555,0.00006759664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002299013,0.00001936042,0.01496731,0.00001724898,0.000008270625,2.187259e-7,0.0001663344,0.0003827223,0.9780706,0.000002704686,0.00008303527,0.006259241],"study_design_scores_gemma":[0.0005114288,0.00007609715,0.007028714,0.00001097326,0.0000126368,1.70114e-7,0.0000117729,0.0008918825,0.975576,0.0002736489,0.01544314,0.0001634677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634891,0.03144374,0.004007997,0.0001879644,0.0001769846,0.0001576925,0.00002908521,0.000005550288,0.0005018822],"genre_scores_gemma":[0.9904317,0.007109377,0.001038248,0.0005415129,0.0002862778,0.00007483707,0.00005986294,0.0000244745,0.0004337234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02694258,"threshold_uncertainty_score":0.50443,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2990428470","doi":"10.1186/s13059-019-1824-y","title":"DNA methylation aging clocks: challenges and recommendations","year":2019,"lang":"en","type":"review","venue":"Genome biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1103,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Genetics; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Institute of Mental Health; National Institute for Health and Care Research; National Institute on Aging; Department of Health and Social Care; Medical Research Council; National Institutes of Health; RWTH Aachen University; Economic and Social Research Council; University College London Hospitals NHS Foundation Trust; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Alzheimer’s Research UK; Cancer Research UK; Biotechnology and Biological Sciences Research Council; ZonMw; Joint Programming Initiative A healthy diet for a healthy life; Deutsche Krebshilfe; National Natural Science Foundation of China; National Cancer Institute; University of Bristol; Deutsche Forschungsgemeinschaft; Diabetes UK; Bundesministerium für Bildung und Forschung; National Science Foundation; UCLH Biomedical Research Centre; American Association for Cancer Research","keywords":"Biology; Epigenomics; DNA methylation; Epigenetics; Human genetics; Evolutionary biology; Computational biology; Longevity; Biomarker; Molecular clock; Population; Genetics; CpG site; Gene; Gene expression; Demography","retraction":null,"screen_n_in":null,"score":{"opus":0.0875488202517343,"gpt":0.3625280585721039,"spread":0.2749792383203696,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003938087,0.0003092623,0.0006811682,0.0001493828,0.00007204486,0.00001680535,0.0001780619,0.0006302081,0.00002351101],"category_scores_gemma":[0.00006337611,0.0002767998,0.0001755592,0.00006513657,0.00005773445,0.000002499168,0.0002033635,0.0001565337,0.00004588133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000248477,"about_ca_system_score_gemma":0.00009383978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002635763,"about_ca_topic_score_gemma":0.00001056976,"domain_scores_codex":[0.9983186,0.0003248516,0.0004129392,0.0006406436,0.00004312568,0.000259838],"domain_scores_gemma":[0.999075,0.00006851471,0.000292702,0.0004401386,0.00005595432,0.00006768597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001431027,0.00001074946,0.000003744208,0.000983925,0.0001167769,2.048174e-7,0.00002715468,6.159827e-7,0.002696797,0.000341181,0.00001480525,0.9958026],"study_design_scores_gemma":[0.0001084068,0.0001617298,0.00003289261,0.000179813,0.0001696467,0.000005326161,0.00001419121,9.583033e-7,0.0001223155,0.0003113226,0.9985911,0.0003022455],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001147747,0.9971684,0.0004287712,0.000113724,0.000397702,0.0004322088,0.00008088211,0.00001350663,0.001250006],"genre_scores_gemma":[0.0002172407,0.9954649,0.0005328389,0.00002737112,0.0005107323,0.00005912737,0.002750477,0.00004650242,0.0003908448],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9985763,"threshold_uncertainty_score":0.9999684,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1982315838","doi":"10.1016/s1097-2765(02)00741-4","title":"MLL Targets SET Domain Methyltransferase Activity to Hox Gene Promoters","year":2002,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1054,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Biology; Hox gene; Histone methyltransferase; Histone H3; Regulation of gene expression; Histone; Genetics; Histone methylation; DNA methylation; Gene; Promoter; Gene expression; Molecular biology","retraction":null,"screen_n_in":null,"score":{"opus":0.0116939321585763,"gpt":0.2323722370282718,"spread":0.2206783048696954,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002097894,0.0002407982,0.000174429,0.00007180246,0.00008265238,0.00003694126,0.0002075094,0.000182138,0.00008413856],"category_scores_gemma":[0.00002889561,0.0002538663,0.0001478901,0.0001542361,0.00003442069,0.000003796768,0.00007958572,0.0001100509,0.00008844923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002100214,"about_ca_system_score_gemma":0.00001856854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002382517,"about_ca_topic_score_gemma":0.00001275925,"domain_scores_codex":[0.998516,0.0001550501,0.0001822246,0.0005497575,0.0002172843,0.0003796994],"domain_scores_gemma":[0.999114,0.000007001001,0.00004740641,0.0005352802,0.00006300594,0.0002333265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002911401,0.0001177581,0.0001102653,0.00001616288,0.00002740795,0.00004549429,0.0001375099,0.000377464,0.9945533,0.000006182619,0.0003888825,0.004190461],"study_design_scores_gemma":[0.0004669025,0.0003509663,0.0002360678,0.000003478407,0.00001892829,0.000001923611,0.00000938122,0.0001184603,0.9501536,0.000107946,0.04822266,0.0003096161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8869293,0.001784615,0.1071589,0.0003810577,0.0001186792,0.0003708006,0.00003726609,0.00001916465,0.003200239],"genre_scores_gemma":[0.9898374,0.0001710936,0.008669257,0.0004460341,0.00008962402,0.00003755419,0.00008396155,0.00005085127,0.0006142267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1029081,"threshold_uncertainty_score":0.9999914,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2129915465","doi":"10.1186/s13059-014-0503-2","title":"Functional normalization of 450k methylation array data improves replication in large cancer studies","year":2014,"lang":"en","type":"article","venue":"Genome biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1009,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Jewish General Hospital; University of Toronto; Ontario Institute for Cancer Research; Ottawa Hospital; McGill University; Douglas Mental Health University Institute","funders":"National Institute of Dental and Craniofacial Research; National Institute of General Medical Sciences; National Cancer Institute","keywords":"Biology; Human genetics; Methylation; Computational biology; Normalization (sociology); Replication (statistics); DNA methylation; Genetics; Cancer; Epigenetics; Bioinformatics; Evolutionary biology; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.05226886351996257,"gpt":0.3455371985945553,"spread":0.2932683350745928,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006203512,0.00009390758,0.0001516143,0.00007537071,0.00004045765,0.000003706404,0.0001583763,0.0001381489,0.0000134427],"category_scores_gemma":[0.0003329236,0.00008775579,0.00002452867,0.0001142949,0.00005288624,0.000007074492,0.0001167019,0.00004213786,0.000001850929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001742941,"about_ca_system_score_gemma":0.00003885645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004082853,"about_ca_topic_score_gemma":0.0002401134,"domain_scores_codex":[0.9989484,0.0001292817,0.0002957241,0.0004237466,0.00005505107,0.0001478281],"domain_scores_gemma":[0.9989948,0.00002677887,0.0001867622,0.0006229334,0.0001465649,0.00002210756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003136972,0.0000280143,0.02333702,0.00001860622,0.00003468178,1.530223e-8,0.00005834522,0.0003158309,0.9713203,0.0005423431,0.0000251739,0.004288304],"study_design_scores_gemma":[0.0009600652,0.0003772965,0.2295415,0.00001132917,0.00003788307,5.913712e-7,0.0001204848,0.001372733,0.705328,0.003155758,0.05881368,0.0002806829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8931601,0.01289354,0.09299666,0.0001795139,0.0002765068,0.000195811,0.0001042367,0.000007782236,0.0001858295],"genre_scores_gemma":[0.9935068,0.002224205,0.0008446136,0.00006993875,0.000275982,0.00003099493,0.002949828,0.00001021436,0.00008744943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2659923,"threshold_uncertainty_score":0.3578577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2074750860","doi":"10.1038/nn.3786","title":"Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci","year":2014,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1006,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; National Human Genome Research Institute; National Institute on Aging","keywords":"CpG site; DNA methylation; Methylation; Biology; Gene; Genetics; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.01172674519452725,"gpt":0.2809473099680377,"spread":0.2692205647735104,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002793575,0.0001113901,0.00007617208,0.00006557585,0.0001201064,0.00005254729,0.000128685,0.0001453358,0.000004002805],"category_scores_gemma":[0.0004166549,0.0001052906,0.00002791449,0.0001884704,0.00007314454,0.00001110172,0.0000832295,0.0001339804,0.000002334615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001195634,"about_ca_system_score_gemma":0.00002419838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001327809,"about_ca_topic_score_gemma":0.0001012542,"domain_scores_codex":[0.9989684,0.0001186905,0.0001344229,0.0004337207,0.0001688306,0.0001759075],"domain_scores_gemma":[0.9995176,0.0000365437,0.000060029,0.0002457997,0.00003658075,0.0001034679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002305263,0.00002057189,0.01672451,0.00000298468,0.000001273175,8.317954e-7,0.00003250914,0.0002639104,0.9801553,0.0004384046,0.0001642423,0.002172337],"study_design_scores_gemma":[0.0004637672,0.0002221319,0.3694102,0.00001018257,0.00001536014,0.000002147577,0.000002998243,0.004081635,0.4834841,0.0008815241,0.1411346,0.0002913133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939007,0.002226996,0.001859436,0.001155408,0.0001924644,0.0001588524,0.0000159213,0.000009972995,0.0004803146],"genre_scores_gemma":[0.9973887,0.00006137969,0.0001846681,0.001836851,0.0001034437,0.000009791794,0.00002048838,0.00001301683,0.0003816471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4966713,"threshold_uncertainty_score":0.4293627,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2053758959","doi":"10.1016/j.molcel.2010.12.011","title":"Genome-wide Identification of Polycomb-Associated RNAs by RIP-seq","year":2010,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":983,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Ministry of Education, Science and Technology; Howard Hughes Medical Institute","keywords":"PRC2; Biology; Polycomb-group proteins; Genetics; Transcriptome; Genome; Gene; RNA; Computational biology; Chromatin; Histone H3; Gene expression; Repressor","retraction":null,"screen_n_in":null,"score":{"opus":0.003292284781495733,"gpt":0.2106623298510377,"spread":0.207370045069542,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002722846,0.000133499,0.0001255133,0.00004443104,0.00004697422,0.00002235814,0.0002085133,0.0002180464,0.00002833735],"category_scores_gemma":[0.0001279459,0.0001472343,0.0001063837,0.0001064226,0.00005920579,0.000002664073,0.00006254092,0.0001185114,0.00001600812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008165695,"about_ca_system_score_gemma":0.00003863397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002784651,"about_ca_topic_score_gemma":0.00001635501,"domain_scores_codex":[0.9989664,0.00006112442,0.0003141399,0.0002934174,0.000172381,0.0001925597],"domain_scores_gemma":[0.9991169,0.000009904391,0.0002207519,0.0004480526,0.0001288089,0.000075572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008786737,0.0001088117,0.003262608,0.000009589603,0.00002278034,0.000001224552,0.00002279774,0.00003758858,0.9960116,0.000018222,0.0001442382,0.0003518129],"study_design_scores_gemma":[0.0003231994,0.00008454935,0.008854116,0.000001493228,0.00002264187,2.499974e-7,0.000008119679,0.00004542496,0.9763847,0.0002663,0.01385379,0.0001554314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847938,0.001231166,0.01094484,0.00006101794,0.0001893688,0.0001611185,0.00003655134,0.00001044574,0.002571626],"genre_scores_gemma":[0.9973455,0.0001016268,0.0003180539,0.00007343084,0.00003416284,0.000009916715,0.0005982272,0.0000306277,0.001488453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01962685,"threshold_uncertainty_score":0.6004041,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2146794662","doi":"10.1186/gb-2014-15-2-r24","title":"Aging of blood can be tracked by DNA methylation changes at just three CpG sites","year":2014,"lang":"en","type":"article","venue":"Genome biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":958,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Heinz Nixdorf Stiftung; RWTH Aachen University; Stem Cell Network","keywords":"Biology; DNA methylation; CpG site; Human genetics; Genome Biology; Evolutionary biology; Methylation; DNA; Computational biology; Genetics; Ancient DNA; Genomics; Genome; Gene; Demography; Gene expression; Population","retraction":null,"screen_n_in":null,"score":{"opus":0.02237749524620415,"gpt":0.2612908318895717,"spread":0.2389133366433676,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003182437,0.0001548636,0.0002076197,0.00006100679,0.00007819432,0.00000630476,0.0001539993,0.000241437,0.00004843996],"category_scores_gemma":[0.00008114294,0.0001473692,0.00006331527,0.00007455752,0.0001066972,0.000001462071,0.0001067749,0.00005198491,0.00000347045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001090104,"about_ca_system_score_gemma":0.00001795776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004287079,"about_ca_topic_score_gemma":0.0006872666,"domain_scores_codex":[0.9989905,0.0001166523,0.0002241162,0.0003520684,0.00006410573,0.0002525074],"domain_scores_gemma":[0.9993403,0.00003123235,0.0001755784,0.0003056431,0.00008192458,0.0000653123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001678391,0.00002762863,0.0081602,0.00001627334,0.00005709191,1.263126e-7,0.00006007935,0.0000127579,0.9885249,0.0001734439,0.00004673183,0.002903961],"study_design_scores_gemma":[0.0004268728,0.0005121549,0.007604439,0.000002250599,0.0000548791,0.000001259072,0.0000135367,0.00003037696,0.9459172,0.0004547593,0.04480577,0.0001765329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912271,0.005028251,0.00247111,0.0004680962,0.0001170857,0.0001445478,0.000116921,0.00001131903,0.0004155964],"genre_scores_gemma":[0.9968477,0.0004756188,0.0004803665,0.0001603539,0.0002546292,0.00002115969,0.00145832,0.00002068977,0.0002811804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04475904,"threshold_uncertainty_score":0.6009541,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2062927905","doi":"10.1038/nature11262","title":"A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response","year":2012,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":958,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; Versus Arthritis; Wellcome Trust","keywords":"Demethylase; Subfamily; Epigenetics; Histone; Biology; Chromatin; Proinflammatory cytokine; Context (archaeology); Small molecule; Biochemistry; Cell biology; Inflammation; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.005100822089425351,"gpt":0.2542507990759661,"spread":0.2491499769865408,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007869219,0.0001586167,0.00009852642,0.00003747539,0.0001472082,0.00002364692,0.0001589461,0.0009294074,0.00001153792],"category_scores_gemma":[0.0005021582,0.0001113301,0.00008904147,0.0001379955,0.00006162583,0.000006729523,0.00008945822,0.000781253,0.00001953871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002379119,"about_ca_system_score_gemma":0.00006781216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002450731,"about_ca_topic_score_gemma":0.000006280485,"domain_scores_codex":[0.9988681,0.0002667464,0.0001519884,0.0002314922,0.0001765734,0.0003050803],"domain_scores_gemma":[0.9992903,0.00005584299,0.00008034326,0.0003477247,0.0001244548,0.0001013372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003611187,0.00004263942,0.004204937,0.000009047299,0.00003459756,0.000001422096,0.0001630568,0.00003090864,0.9913952,0.00004729956,0.002092555,0.001617231],"study_design_scores_gemma":[0.0002445061,0.0001072809,0.0356665,0.000005415514,0.00001473848,0.000003827561,0.00003403695,0.00003009412,0.8767131,0.0001200277,0.08691593,0.000144558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759246,0.02242748,0.0001390301,0.0003691016,0.0003360768,0.0002896653,0.00001510236,0.00001700283,0.0004819294],"genre_scores_gemma":[0.9972826,0.0001296321,0.0004036064,0.0003007195,0.0008122173,0.00003428309,0.00003332877,0.00002856274,0.0009750495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1146821,"threshold_uncertainty_score":0.7168441,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2150170782","doi":"10.1038/ng.465","title":"SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":952,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"Biology; Cancer research; SOX2; Ectopic expression; Esophagus; Oncogene; Cellular differentiation; Transcription factor; Cell; Cell culture; Gene; Genetics; Cell cycle","retraction":null,"screen_n_in":null,"score":{"opus":0.01017174342488764,"gpt":0.2744493561528173,"spread":0.2642776127279297,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002354092,0.0002456644,0.0002050211,0.00008233784,0.00007855539,0.00004648929,0.0002034211,0.0007068408,0.00001009018],"category_scores_gemma":[0.00003719458,0.0002557165,0.00006127967,0.0001404366,0.00004131162,0.000004285612,0.00006935061,0.0003502559,0.000002016209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000194543,"about_ca_system_score_gemma":0.00008267014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001273903,"about_ca_topic_score_gemma":0.00007809447,"domain_scores_codex":[0.9985232,0.00008225437,0.0002844922,0.0005650866,0.0002093284,0.0003356197],"domain_scores_gemma":[0.9991645,0.00001519708,0.00008674266,0.0004663693,0.0001017711,0.0001654778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001047403,0.0002058242,0.06296417,0.00003177196,0.00001055774,0.00002190651,0.0003057534,0.0004876705,0.9281814,0.00003626108,0.0002518871,0.007398095],"study_design_scores_gemma":[0.00114885,0.0006799087,0.1215268,0.000004254717,0.00003123266,0.000003721379,0.00004553073,0.001598774,0.8687499,0.0002312671,0.005624247,0.000355464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646088,0.03314276,0.0005679861,0.0001067515,0.0002120206,0.0002210886,0.00003035585,0.00001265362,0.001097625],"genre_scores_gemma":[0.994186,0.00113968,0.002976274,0.0006460275,0.0005436666,0.000004258904,0.0001751351,0.00003083255,0.0002981579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05943146,"threshold_uncertainty_score":0.9999895,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2036284273","doi":"10.1111/acel.12349","title":"<scp>DNA</scp> methylation and healthy human aging","year":2015,"lang":"en","type":"review","venue":"Aging Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":947,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Learning Partnership; Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Child and Family Research Institute; Canadian Institute for Advanced Research","keywords":"Epigenetics; DNA methylation; Biology; Epigenome; CpG site; Genetics; Methylation; Telomere; Epigenomics; Epigenetics of physical exercise; Senescence; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.04676490933599096,"gpt":0.3534713865845835,"spread":0.3067064772485926,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007343864,0.0003438258,0.0005984346,0.0001281127,0.0001450173,0.0000706035,0.0001752984,0.0003682865,0.000002265054],"category_scores_gemma":[0.00006271518,0.0003302762,0.0001599729,0.0001275234,0.00004503768,0.000004267876,0.0001702592,0.0002240867,0.00001703637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003824453,"about_ca_system_score_gemma":0.0001588714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002833051,"about_ca_topic_score_gemma":0.00001092913,"domain_scores_codex":[0.9982647,0.0002305832,0.0004320127,0.000579937,0.0001747234,0.0003181017],"domain_scores_gemma":[0.9988959,0.00005603569,0.0003597051,0.0004257121,0.00009192375,0.000170665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001348985,0.00007751834,0.0001907812,0.009581683,0.0001333842,0.000007923617,0.0002681615,0.00001534703,0.01089612,0.00006765693,0.002916281,0.9758438],"study_design_scores_gemma":[0.0001851321,0.0001149157,0.00001173996,0.0003945593,0.0001798477,0.000003260176,0.00002053147,0.000005621529,0.003083376,0.0001459719,0.9957056,0.0001494207],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003731621,0.9906555,0.0003891645,0.00001102207,0.0002128994,0.00034732,0.00001482116,0.00002206758,0.004615576],"genre_scores_gemma":[0.001430207,0.9946532,0.0004915218,0.00004946666,0.0005571104,0.00002347026,0.0008451761,0.00007887744,0.001870917],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9927893,"threshold_uncertainty_score":0.9999149,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1981259598","doi":"10.1016/j.cell.2007.10.039","title":"New Nomenclature for Chromatin-Modifying Enzymes","year":2007,"lang":"en","type":"letter","venue":"Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":937,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; Acetyltransferases; Chromatin; Histone Acetyltransferases; Methyltransferase; Lysine; Enzyme; Biochemistry; Genetics; Histone; Nomenclature; Computational biology; Acetylation; DNA; Methylation; Gene; Ecology; Amino acid; Taxonomy (biology)","retraction":null,"screen_n_in":null,"score":{"opus":0.0165519727382418,"gpt":0.2660670371208258,"spread":0.249515064382584,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001328898,0.0002491667,0.0001931521,0.00006270705,0.000066489,0.00003891729,0.0002165839,0.001203588,0.00004399476],"category_scores_gemma":[0.00002757882,0.0002476892,0.0001773032,0.00004644029,0.00001976321,0.00000122726,0.0000587991,0.0003578276,0.00001839322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001794938,"about_ca_system_score_gemma":0.0001195962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001011738,"about_ca_topic_score_gemma":0.000004586745,"domain_scores_codex":[0.9988567,0.00002053955,0.0002193796,0.0004284009,0.0001368508,0.000338136],"domain_scores_gemma":[0.9992899,0.00003290588,0.0001548079,0.0003893303,0.00007009585,0.00006296007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008175328,0.000005531562,0.000007743754,0.0001312557,0.0000191688,0.000004417003,0.0000179054,0.000005164653,0.2165719,0.000002911969,0.7815511,0.001674805],"study_design_scores_gemma":[0.0002040481,0.00008223658,0.000009830288,0.00001054721,0.00002080918,6.038171e-7,0.000001586108,0.000003958409,0.4041488,0.0002645555,0.5950713,0.0001818373],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"methods","genre_gemma":"commentary","genre_scores_codex":[0.02823129,0.1405993,0.5587345,0.1761866,0.006604475,0.004025255,0.0005387287,0.0001656151,0.0849143],"genre_scores_gemma":[0.00918911,0.00189383,0.131408,0.5565925,0.06158804,0.0001170981,0.0160704,0.0005003428,0.2226407],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4273265,"threshold_uncertainty_score":0.9999976,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2113833115","doi":"10.1038/nature04835","title":"ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression","year":2006,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":927,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"H3K4me3; Histone H3; Histone; Effector; Biology; Cell biology; Histone methylation; Chromatin; Histone deacetylase 2; Chromatin immunoprecipitation; Histone code; Promoter; Chemistry; Genetics; Histone deacetylase; DNA methylation; Gene; Gene expression; Nucleosome","retraction":null,"screen_n_in":null,"score":{"opus":0.006637168087479237,"gpt":0.2857316571902206,"spread":0.2790944891027414,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002001158,0.0001479334,0.0001292058,0.00007546929,0.00009528602,0.0000192321,0.000119513,0.001603762,0.00001827469],"category_scores_gemma":[0.0001015848,0.000138194,0.00007360984,0.000173809,0.00002076746,0.000004606486,0.00007862429,0.00065123,0.000010226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004267468,"about_ca_system_score_gemma":0.0000330385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003912249,"about_ca_topic_score_gemma":0.00004641702,"domain_scores_codex":[0.9989593,0.00006767572,0.0001882321,0.0004076609,0.0001961841,0.0001809293],"domain_scores_gemma":[0.9993106,0.00001303287,0.0001028169,0.0003511824,0.0001569653,0.00006541053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009432327,0.00004178216,0.0004316728,0.00000469081,0.00001358417,0.000001983713,0.00004018495,0.0007378895,0.9894774,0.00009437732,0.001827122,0.00723499],"study_design_scores_gemma":[0.0003092327,0.00009762915,0.01476763,0.00000886176,0.00001346274,0.000001222466,0.00000952536,0.00003356807,0.8778604,0.001337805,0.1053975,0.000163182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821141,0.004958573,0.008502077,0.0007113428,0.0002798827,0.0002148348,0.00002332264,0.00002025009,0.003175567],"genre_scores_gemma":[0.9869292,0.00008954747,0.009775949,0.0003994293,0.0007834357,0.00001518632,0.0006270479,0.00002537314,0.001354849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.111617,"threshold_uncertainty_score":0.9996924,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2013245174","doi":"10.1523/jneurosci.3652-05.2005","title":"Reversal of Maternal Programming of Stress Responses in Adult Offspring through Methyl Supplementation: Altering Epigenetic Marking Later in Life","year":2005,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":902,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Douglas Mental Health University Institute; Douglas College","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Offspring; Epigenetics; Psychology; Developmental psychology; Biology; Pregnancy; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.02472442163877084,"gpt":0.3136909905470572,"spread":0.2889665689082863,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005102993,0.00008216781,0.0001629465,0.0001386134,0.00001913316,0.00001685736,0.0002040889,0.00004055291,0.000003196557],"category_scores_gemma":[0.0002722308,0.00007747898,0.00005256653,0.000173201,0.00006575294,0.00002663995,0.00005854779,0.00009132569,6.759532e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000157857,"about_ca_system_score_gemma":0.00007685579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003229102,"about_ca_topic_score_gemma":0.00007835751,"domain_scores_codex":[0.9986806,0.0001137728,0.0006419276,0.000151479,0.000246731,0.000165469],"domain_scores_gemma":[0.9992781,0.00002851158,0.0004364098,0.0001118531,0.0001051774,0.00003993536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001215243,0.00004678225,0.1490577,0.0000283089,0.00000230261,0.000006837992,0.0001988125,0.004169689,0.8418351,0.000004553998,8.793089e-7,0.00452751],"study_design_scores_gemma":[0.0004103397,0.0002415149,0.2672279,0.00009029733,0.000004190844,0.000006418402,0.00007071098,0.0002414918,0.731414,0.00001150933,0.0002298208,0.00005188846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976591,0.0003751886,0.001594936,0.0001282707,0.0001328776,0.00007836073,0.000004443394,7.679376e-7,0.00002606673],"genre_scores_gemma":[0.9897772,0.0006686206,0.009416075,0.00004827539,0.00006969819,0.000001581671,7.457337e-7,0.000006583734,0.00001118982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1181701,"threshold_uncertainty_score":0.3159501,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016923091","doi":"10.1038/nature12362","title":"Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells","year":2013,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":882,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"DNA demethylation; DNA methylation; Epigenetics; Biology; Molecular biology; 5-Hydroxymethylcytosine; Demethylation; Methylation; Chemistry; DNA; Gene; Gene expression; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.00455691203124772,"gpt":0.2320055858160686,"spread":0.2274486737848209,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552863,0.0001190624,0.00009633518,0.00006693705,0.00003347567,0.00004053573,0.00007828504,0.0006438178,0.00001493791],"category_scores_gemma":[0.00004171027,0.0001081724,0.00002445113,0.00007700005,0.00002636925,0.000008307095,0.00006224656,0.0003951829,0.00000915059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001132733,"about_ca_system_score_gemma":0.0000241845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006233573,"about_ca_topic_score_gemma":0.0001790284,"domain_scores_codex":[0.9992337,0.00005567508,0.0001533933,0.0002689465,0.0001242192,0.0001641139],"domain_scores_gemma":[0.9996401,0.00001789195,0.00006323502,0.0001533151,0.00006907462,0.00005634719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001112689,0.0000222426,0.003095469,0.00001063638,0.000009484069,9.5711e-7,0.00008368753,0.00007243222,0.9844871,0.00001042406,0.0001533709,0.0120431],"study_design_scores_gemma":[0.0004141378,0.0001182878,0.04919937,0.000009992516,0.000005602011,9.273248e-7,0.00005127543,0.0001037296,0.9455888,0.001006835,0.00334028,0.0001607518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957485,0.003223277,0.0002709533,0.0001144251,0.000158055,0.0002451555,0.000009878218,0.000006690645,0.0002231162],"genre_scores_gemma":[0.9981234,0.0004809282,0.0006768059,0.000170485,0.00007350351,0.00002220678,0.000043326,0.00001455912,0.0003947757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0461039,"threshold_uncertainty_score":0.4965712,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2010711123","doi":"10.1016/j.ccr.2013.04.011","title":"EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation","year":2013,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":841,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"EZH2; Germinal center; Histone methyltransferase; Biology; Somatic cell; Somatic hypermutation; B cell; Chromatin; Cancer research; Gene silencing; Histone; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01273970078456645,"gpt":0.2634424101023659,"spread":0.2507027093177994,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006953368,0.0001030464,0.00008254419,0.00002337984,0.00009763244,0.00004515462,0.0000521886,0.00008958964,0.00006438193],"category_scores_gemma":[0.000007106671,0.00009921591,0.00004793976,0.00003365015,0.00002503404,0.00003564866,0.00001171295,0.00002083938,0.00001151801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003169064,"about_ca_system_score_gemma":0.00003824093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004544236,"about_ca_topic_score_gemma":0.00002706321,"domain_scores_codex":[0.9993815,0.00001704016,0.0002130271,0.0001595453,0.00007219285,0.0001566329],"domain_scores_gemma":[0.9996073,0.000006753276,0.00009151111,0.000120924,0.000115613,0.00005786452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000185573,0.00003707318,0.0004161517,0.0002135218,0.00001173199,5.949428e-8,0.001054618,0.00003947459,0.9663092,0.00001744381,0.0006334884,0.03124862],"study_design_scores_gemma":[0.001070965,0.0001721793,0.0008632392,0.0000218392,0.00003013761,0.000002511379,0.0001784772,0.007553382,0.9690921,0.0007978551,0.02004886,0.0001683946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646778,0.001710727,0.03100765,0.0003208885,0.000106582,0.0007495484,0.00006903189,0.00000987323,0.001347919],"genre_scores_gemma":[0.9960331,0.0008303532,0.001617463,0.000165922,0.0001074043,0.0003267225,0.0003630792,0.00001592332,0.000540062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0313553,"threshold_uncertainty_score":0.4045908,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2099562966","doi":"10.1016/s0140-6736(13)62674-4","title":"DNA methylation and body-mass index: a genome-wide analysis","year":2014,"lang":"en","type":"article","venue":"The Lancet","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":793,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Public Health Ontario","funders":"Helmholtz Zentrum München; Fondation pour la Recherche Médicale; Bundesministerium für Bildung und Forschung; European Commission; King's College London; Canadian Institutes of Health Research; National Institute for Health and Care Research; British Heart Foundation; Wellcome Trust; NIHR BioResource; Heart and Stroke Foundation of Canada","keywords":"DNA methylation; Methylation; Cohort; Body mass index; Epigenetics; CpG site; Genetics; Genome-wide association study; Genetic association; Biology; Oncology; Medicine; Internal medicine; Gene; Genotype; Single-nucleotide polymorphism; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.01223471946487438,"gpt":0.2553138061754293,"spread":0.2430790867105549,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004915259,0.00007660452,0.0001570306,0.00003610364,0.00007199983,0.00003150184,0.0001214734,0.00006692969,0.00001017355],"category_scores_gemma":[0.0001114801,0.00005566715,0.00004993224,0.0001333827,0.00003834719,0.000001857293,0.00004353318,0.00005037877,0.000003870472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003948939,"about_ca_system_score_gemma":0.000007396401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001272556,"about_ca_topic_score_gemma":0.00004121041,"domain_scores_codex":[0.9993957,0.0001082106,0.0001088198,0.0001742519,0.00007951626,0.0001334987],"domain_scores_gemma":[0.9994668,0.00003458252,0.00006290562,0.0003667717,0.00003490185,0.00003399359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005067469,0.00001011184,0.2425818,0.00000974597,0.0002743279,1.844142e-7,0.00005800152,0.001532292,0.7511855,0.000298947,0.0001665528,0.003831764],"study_design_scores_gemma":[0.000487133,0.00009230389,0.8142084,0.000001893813,0.0001879116,2.738351e-7,0.00001547373,0.003740353,0.0966796,0.003226867,0.08119813,0.0001616261],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9429687,0.0009328045,0.05285364,0.0006080192,0.00003227958,0.00006932129,0.000006617226,0.000008393222,0.002520243],"genre_scores_gemma":[0.9981126,0.0003702936,0.000501975,0.000287044,0.0004253776,0.000006799693,0.00008263834,0.000008120655,0.0002051224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.654506,"threshold_uncertainty_score":0.2270041,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2505539351","doi":"10.1186/s13059-016-1030-0","title":"An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease","year":2016,"lang":"en","type":"article","venue":"Genome biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":789,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Center for Advancing Translational Sciences; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Institute on Aging; University at Buffalo; MedStar Health Research Institute; Wake Forest University; University of Pittsburgh; U.S. Department of Health and Human Services; National Institutes of Health; Ohio State University; National Heart, Lung, and Blood Institute; Brigham and Women's Hospital; National Cancer Institute","keywords":"Epigenetics; Demography; Biology; Mortality rate; Disease; Physiology; Ethnic group; Life expectancy; Medicine; Gerontology; Internal medicine; Genetics; Population; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01204599034083154,"gpt":0.2815035904373481,"spread":0.2694576000965165,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002493548,0.0001330575,0.0002560562,0.0001247031,0.00004584137,0.000004875803,0.0001357394,0.0001477616,0.0000550178],"category_scores_gemma":[0.00004973122,0.00009999366,0.00009238964,0.0001362954,0.0001949816,0.000002535417,0.0001059517,0.00002840077,0.000003636476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000893425,"about_ca_system_score_gemma":0.00004821454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002023491,"about_ca_topic_score_gemma":0.00003485196,"domain_scores_codex":[0.9988643,0.0001791888,0.0002425055,0.0004235811,0.00005556874,0.0002348454],"domain_scores_gemma":[0.9991774,0.0000328618,0.00009109682,0.0004483688,0.00006662635,0.0001836611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005989326,0.00003680071,0.2737233,0.000004152255,0.0001318181,5.495704e-7,0.00001442208,0.00005350529,0.7224293,0.00007337234,0.000003852359,0.003469072],"study_design_scores_gemma":[0.0003349235,0.0006513564,0.9215695,0.000002281197,0.0002294173,8.789173e-7,0.00001050259,0.00005580989,0.06837489,0.0007004611,0.007883498,0.0001865469],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859798,0.007588236,0.005851954,0.0001866974,0.00005086695,0.0001191688,0.0001637073,0.00000727243,0.00005231594],"genre_scores_gemma":[0.9972785,0.001604025,0.0004339559,0.0001201957,0.00009308752,0.00001077915,0.0002597666,0.00001346486,0.0001862821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6540544,"threshold_uncertainty_score":0.4077623,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2553059833","doi":"10.1016/j.cell.2016.10.026","title":"Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells","year":2016,"lang":"en","type":"article","venue":"Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":779,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Instituto de Salud Carlos III; Medical Research Council; Canadian Institutes of Health Research; Max-Planck-Gesellschaft; Lundbeckfonden; Ministerio de Economía y Competitividad; NIHR Cambridge Biomedical Research Centre; European Commission; University of Cambridge; European Molecular Biology Laboratory; University of Oxford; NHS Blood and Transplant; McGill University; European Bioinformatics Institute; National Institute for Health and Care Research; Genome Canada; British Heart Foundation; Wellcome Trust","keywords":"Biology; Epigenetics; Quantitative trait locus; DNA methylation; Expression quantitative trait loci; Epigenome; Genetics; Genome-wide association study; Epigenomics; Allele; Histone; Genetic variation; Computational biology; Gene; Gene expression; Genotype; Single-nucleotide polymorphism","retraction":null,"screen_n_in":null,"score":{"opus":0.006209911734211974,"gpt":0.2096002954075117,"spread":0.2033903836732998,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001026561,0.00007532956,0.00008492202,0.00004825457,0.00002237044,0.00000414998,0.00006271023,0.00008819304,0.00003217644],"category_scores_gemma":[0.000006432118,0.00006450462,0.00003425954,0.00003980116,0.00005405873,0.000002099901,0.00002042247,0.00002237827,0.000002426358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007830753,"about_ca_system_score_gemma":0.00001972152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002685173,"about_ca_topic_score_gemma":0.00001962309,"domain_scores_codex":[0.999398,0.00004207361,0.0001984745,0.000184039,0.00007073591,0.0001066792],"domain_scores_gemma":[0.9997188,0.000009190667,0.00006395725,0.0001411567,0.00003433255,0.00003253197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009098837,0.0000359314,0.00389182,0.00001232071,0.000004610413,3.219557e-7,0.00008149771,0.00008092734,0.9947928,0.00005148003,0.000003773455,0.001035418],"study_design_scores_gemma":[0.0005252348,0.0001153284,0.2526426,0.000007963656,0.000006568167,1.814026e-7,0.000006871206,0.00001224214,0.7456805,0.00039036,0.0005432544,0.00006894062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885435,0.001913503,0.008841032,0.00002451081,0.00006253338,0.00009715804,0.00001126765,0.000002129884,0.0005043425],"genre_scores_gemma":[0.9977554,0.0008936903,0.0009341422,0.000007548532,0.00003857864,0.000004347716,0.00001044696,0.000009861552,0.0003459781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2491123,"threshold_uncertainty_score":0.2630422,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2121471393","doi":"10.1016/j.ajhg.2008.01.008","title":"Epigenomic Profiling Reveals DNA-Methylation Changes Associated with Major Psychosis","year":2008,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":776,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health","keywords":"Epigenomics; DNA methylation; Psychosis; Profiling (computer programming); Computational biology; Biology; Genetics; Medicine; Psychiatry; Computer science; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.02233375735204721,"gpt":0.2790641784117239,"spread":0.2567304210596766,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005780658,0.0001678969,0.0002743499,0.0000880052,0.0002529341,0.00002018172,0.000299306,0.00005186932,0.000006804115],"category_scores_gemma":[0.00006473952,0.0001178974,0.00009414021,0.0001893843,0.0002646771,0.00000340697,0.00004096275,0.0001494279,0.000001825115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003041137,"about_ca_system_score_gemma":0.00006394136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000608001,"about_ca_topic_score_gemma":0.00003170151,"domain_scores_codex":[0.9987129,0.0002366587,0.0003737091,0.0001740991,0.0002698617,0.0002327732],"domain_scores_gemma":[0.9982585,0.00004026444,0.0009943844,0.0003090697,0.0003102935,0.0000874972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000102366,0.00005436776,0.02469736,0.000003201774,0.0001661016,0.000004777821,0.0002498381,0.000387949,0.9710109,0.000009260968,0.0001079698,0.003205887],"study_design_scores_gemma":[0.0008343673,0.005472532,0.1861196,0.00004304612,0.0001590646,0.00006059491,0.0002834806,0.00003144226,0.8053657,0.0004314668,0.0008717744,0.0003268796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958709,0.002285003,0.001248947,0.0002298368,0.00007252959,0.0001498762,0.000007366402,0.000005180013,0.0001303966],"genre_scores_gemma":[0.9961836,0.001446627,0.001601167,0.0001521127,0.0003965238,0.00000498357,0.00002168271,0.00003815009,0.000155124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1656452,"threshold_uncertainty_score":0.4807716,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2173367702","doi":"10.1038/ncomms9570","title":"The transcriptional landscape of age in human peripheral blood","year":2015,"lang":"en","type":"review","venue":"Nature Communications","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":760,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Discovery Centre","funders":"National Center for Advancing Translational Sciences; National Institute on Aging; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; European Commission; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute for Health and Care Research","keywords":"Transcriptome; Epigenetics; DNA methylation; CpG site; Ageing; Biology; Methylation; Gene; Gene expression; Genetics; Regulation of gene expression; Computational biology; Bioinformatics","retraction":null,"screen_n_in":null,"score":{"opus":0.04821631296329774,"gpt":0.371852450536134,"spread":0.3236361375728362,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004341642,0.0001484295,0.0003274176,0.0000543223,0.0001282767,0.00002033705,0.0009920257,0.0005669052,0.000003086449],"category_scores_gemma":[0.00007048511,0.000108597,0.0001945866,0.000161672,0.0001279497,0.00000152366,0.0001635062,0.0006000691,7.666096e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001372945,"about_ca_system_score_gemma":0.0001743531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004644305,"about_ca_topic_score_gemma":0.0008029716,"domain_scores_codex":[0.9989352,0.0002909704,0.0003779581,0.0001589295,0.0001241952,0.0001127795],"domain_scores_gemma":[0.9982965,0.00005246367,0.0001803148,0.00131657,0.0001202388,0.00003394146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003312658,0.001357764,0.001215066,0.002654264,0.001107276,0.000005219568,0.0004405444,0.00003638917,0.01511894,0.04754855,0.004096031,0.9263868],"study_design_scores_gemma":[0.0001526206,0.00004282384,0.000113085,0.0002078109,0.0001140592,0.000001745123,0.0000112068,0.000001715196,0.00004378918,0.0001672491,0.9990337,0.0001102149],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002367447,0.9959785,0.000007034565,0.00004919419,0.00007362149,0.0002661648,0.00005679818,0.000003630308,0.003328338],"genre_scores_gemma":[0.01123988,0.985934,0.0004105923,0.000009227419,0.00008098009,0.00007147454,0.001933175,0.00002137823,0.0002993035],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9949377,"threshold_uncertainty_score":0.4428459,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109715726","doi":"10.1038/nbt.1682","title":"Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications","year":2010,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":739,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; National Institute of General Medical Sciences; National Institute on Drug Abuse; National Institute of Environmental Health Sciences; University of Waterloo","keywords":"Methylated DNA immunoprecipitation; Bisulfite sequencing; Illumina Methylation Assay; DNA methylation; Biology; Epigenetics; CpG site; Genomic imprinting; Genetics; Computational biology; DNA sequencing; Differentially methylated regions; Deep sequencing; Genome; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.01877695010311142,"gpt":0.3687117673703512,"spread":0.3499348172672398,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005114263,0.0001214694,0.0002153135,0.0002438989,0.00004960304,0.0000066559,0.0002045894,0.001041494,0.000005644781],"category_scores_gemma":[0.0006766138,0.0001233336,0.00004903007,0.0002951201,0.0001536455,0.000002969624,0.0000645265,0.0003100752,0.000001301873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001044122,"about_ca_system_score_gemma":0.00008369475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001171084,"about_ca_topic_score_gemma":0.00005126053,"domain_scores_codex":[0.9988737,0.00008400565,0.0004508461,0.000353816,0.0001058264,0.0001318435],"domain_scores_gemma":[0.998789,0.00004578388,0.000314157,0.0005645353,0.0002394997,0.00004698805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001852163,0.00004662371,0.00117219,0.00002593973,0.00001570385,3.526063e-8,0.00004109721,0.0002470119,0.9701722,0.00191562,0.0000145866,0.02633051],"study_design_scores_gemma":[0.0001586477,0.000207041,0.009443649,0.000004739287,0.00002444012,4.78355e-7,0.00004125053,0.003292863,0.983885,0.0007005656,0.002130542,0.0001107683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8255298,0.001318068,0.1720512,0.0005229867,0.0001476899,0.0003184401,0.00002953907,0.0000172982,0.00006494646],"genre_scores_gemma":[0.9029913,0.00004942463,0.09676006,0.00002087586,0.000029706,0.00003096787,0.00008044943,0.00001414076,0.00002309227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07746146,"threshold_uncertainty_score":0.8032959,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136691282","doi":"10.1371/journal.pgen.1002629","title":"Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population","year":2012,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":718,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"Wellcome Trust","keywords":"Differentially methylated regions; Biology; DNA methylation; Epigenome; Epigenetics; Methylation; CpG site; Genetics; Longevity; Ageing; Phenotype; Genome-wide association study; Genotype; Gene; Single-nucleotide polymorphism; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.03064955705384771,"gpt":0.2963573792235284,"spread":0.2657078221696807,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000307486,0.0002186851,0.0002563403,0.0001373408,0.0001414317,0.00004785332,0.0001233876,0.0002856401,0.000006916976],"category_scores_gemma":[0.0001738048,0.0002339815,0.00007977952,0.0001624959,0.00005974032,0.000009017515,0.00009036234,0.0001224177,0.000002552975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003502603,"about_ca_system_score_gemma":0.00003036988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005409932,"about_ca_topic_score_gemma":0.0005598579,"domain_scores_codex":[0.9984065,0.0001428367,0.0004617934,0.0003687773,0.0001505539,0.0004695683],"domain_scores_gemma":[0.9992212,0.00006064622,0.0001648219,0.0003042066,0.00007151716,0.0001776291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001583855,0.0002928854,0.1302091,0.0001333094,0.0001465495,0.000007398695,0.0008493809,0.0006281542,0.864163,0.0005105793,0.00002742448,0.00287382],"study_design_scores_gemma":[0.002548122,0.0007628695,0.7987679,0.00008206686,0.0002485836,0.000001619902,0.0001185695,0.00197263,0.181514,0.01064776,0.002466205,0.0008697346],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833168,0.009451568,0.006061885,0.0001155495,0.0002238192,0.0006274432,0.00002180906,0.00002070663,0.0001603544],"genre_scores_gemma":[0.9953482,0.001310838,0.00220642,0.00008797886,0.0001842547,0.00005567932,0.000617636,0.000056701,0.0001323122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6826491,"threshold_uncertainty_score":0.9541488,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2069200751","doi":"10.1016/s1097-2765(03)00091-1","title":"The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation","year":2003,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":713,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"Biology; Histone methylation; Histone methyltransferase; Histone code; Histone H3; Histone; EZH2; Compass; Methylation; Histone H2A; Cell biology; Genetics; DNA methylation; Nucleosome; DNA; Gene expression; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.02069138108277099,"gpt":0.290317183190774,"spread":0.2696258021080031,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006567385,0.0002041315,0.0001650681,0.00005871944,0.0003701067,0.00006905264,0.0001187385,0.0001716306,0.00001086117],"category_scores_gemma":[0.00008634224,0.0001962872,0.0001083568,0.00012798,0.00006826521,0.000009402372,0.00002345942,0.00007892796,0.000004112285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000594915,"about_ca_system_score_gemma":0.00004461563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000171592,"about_ca_topic_score_gemma":0.00001864142,"domain_scores_codex":[0.9984785,0.0001993561,0.0003625989,0.0004465452,0.0002463711,0.0002665839],"domain_scores_gemma":[0.9991742,0.00005417299,0.0001549844,0.0002989655,0.0002074552,0.0001101871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005927409,0.00003733408,0.00007726918,0.00002148499,0.00002689111,2.892272e-7,0.0001612711,0.0003479552,0.9923592,0.0009610546,0.0009638916,0.004984147],"study_design_scores_gemma":[0.0006256718,0.0001777255,0.0003737724,0.000004852918,0.00003727097,6.896427e-7,0.00003058406,0.0008473711,0.7274401,0.001581462,0.2686791,0.0002014327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4395584,0.008635042,0.548869,0.000906756,0.000189427,0.0006972729,0.00004976013,0.00001528107,0.001079045],"genre_scores_gemma":[0.9856006,0.0002442446,0.01186844,0.00048991,0.00006035603,0.00009136947,0.0008392787,0.00004145234,0.0007643287],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5460422,"threshold_uncertainty_score":0.8004362,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2008978345","doi":"10.1038/nature09230","title":"Epigenetics as a unifying principle in the aetiology of complex traits and diseases","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":693,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Epigenetics; Germline; Biology; Phenotype; Histone; Epigenesis; Somatic cell; Genetics; DNA methylation; Heritability; Epigenetic regulation of neurogenesis; Evolutionary biology; Computational biology; DNA; Gene; Gene expression; Chromatin remodeling","retraction":null,"screen_n_in":null,"score":{"opus":0.01066196089556333,"gpt":0.3034593601017241,"spread":0.2927973992061608,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001444748,0.00007070463,0.00008127531,0.00002813589,0.00003317276,0.000007803893,0.0001286876,0.0004917451,0.00001087482],"category_scores_gemma":[0.0001827204,0.00005223919,0.00002741942,0.00006432659,0.00008318856,0.000001084833,0.00004363165,0.0004196196,4.624152e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001305235,"about_ca_system_score_gemma":0.00003055832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000715641,"about_ca_topic_score_gemma":0.0001598374,"domain_scores_codex":[0.9995033,0.00005500223,0.0001132155,0.000151063,0.00007541293,0.0001020461],"domain_scores_gemma":[0.9997113,0.00003225601,0.00004870837,0.0001335267,0.00004555173,0.00002865254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000021295,0.00003995298,0.02736783,0.00001394067,0.000007115723,0.000001272519,0.00009157935,0.00001725629,0.9656559,0.001957354,0.00004870782,0.004777813],"study_design_scores_gemma":[0.0003722438,0.0001683166,0.8226982,0.000004735586,0.00001352463,0.000006195122,0.00006426302,0.0000613767,0.08824826,0.002297325,0.08595918,0.0001063205],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956317,0.003029943,0.00005592485,0.0002870258,0.00005394661,0.0001209913,0.00002024159,0.000002142724,0.0007980852],"genre_scores_gemma":[0.9985723,0.0003035236,0.0006572679,0.000270317,0.00009317111,0.000005420024,0.0000555178,0.000006608992,0.00003588983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8774076,"threshold_uncertainty_score":0.3792788,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2170634666","doi":"10.1038/ng.286","title":"DNA methylation profiles in monozygotic and dizygotic twins","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":670,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression","keywords":"Biology; DNA methylation; Epigenetics; Genetics; Monozygotic twin; CpG site; Buccal swab; Epigenomics; Twin study; Heritability; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.007357303786291861,"gpt":0.2684199468283932,"spread":0.2610626430421014,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002157138,0.000162414,0.0001369123,0.00009381936,0.00004656721,0.00003391762,0.0001213673,0.0004437948,0.000004183188],"category_scores_gemma":[0.0001023929,0.0001606569,0.00003980085,0.0001514427,0.00003448869,0.0000036187,0.0000429672,0.0002208909,0.000002481043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001461012,"about_ca_system_score_gemma":0.00003858498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002190419,"about_ca_topic_score_gemma":0.00002958472,"domain_scores_codex":[0.9989864,0.00005934013,0.0002190108,0.0003549663,0.0001573978,0.0002229221],"domain_scores_gemma":[0.9995133,0.00001378832,0.00006682565,0.0002642426,0.00006738214,0.00007446024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004058494,0.0000810038,0.02608377,0.00001740332,0.00001408819,0.000004100523,0.0001054456,0.0006088162,0.9268485,0.000187523,0.0001168319,0.04589198],"study_design_scores_gemma":[0.0005580211,0.0004022511,0.3685057,0.00001489466,0.00001983033,0.000003500777,0.00002604382,0.0007394672,0.6193364,0.00338279,0.006743161,0.0002678956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793274,0.018392,0.0007413379,0.0002680461,0.0001363384,0.0002414119,0.00000604551,0.00001086657,0.0008765222],"genre_scores_gemma":[0.9944329,0.001640205,0.003191197,0.0002808344,0.0002263487,0.00000556206,0.00007865855,0.00001654737,0.0001277795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3424219,"threshold_uncertainty_score":0.6551397,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1995652309","doi":"10.1016/j.stem.2010.08.002","title":"Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer","year":2010,"lang":"en","type":"review","venue":"Cell stem cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":668,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Biology; Somatic cell; Polycomb-group proteins; Stem cell; Cell biology; Cancer stem cell; Cancer research; Computational biology; Genetics; Transcription factor; Gene; Repressor","retraction":null,"screen_n_in":null,"score":{"opus":0.02277004561347768,"gpt":0.2729988263881582,"spread":0.2502287807746805,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002756929,0.000518705,0.001045224,0.0001042432,0.00007357549,0.00003548089,0.0003200793,0.0009111353,0.00001714084],"category_scores_gemma":[0.000002470424,0.0004449317,0.000326138,0.0001399083,0.0001045371,0.000003699721,0.0001955382,0.0002984196,0.00001139268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002612011,"about_ca_system_score_gemma":0.0001737138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003890386,"about_ca_topic_score_gemma":0.00002541361,"domain_scores_codex":[0.9978295,0.0002044899,0.0007629275,0.0006720593,0.0001956342,0.0003353951],"domain_scores_gemma":[0.9981471,0.00003349942,0.0008216639,0.0007486735,0.00008281675,0.000166239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007799766,0.0001620993,0.00003558778,0.02160578,0.00007146295,0.000002052493,0.00005624915,0.000006647613,0.3704444,0.000002726528,0.00004408233,0.6075611],"study_design_scores_gemma":[0.0003734092,0.0001383325,0.000005189208,0.001011878,0.0002793192,0.000001054391,0.00002052309,0.00002547444,0.4048354,0.000002277111,0.5928994,0.0004077566],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02500758,0.9724429,0.0002469955,0.000001666925,0.0004093263,0.001470237,0.0001236712,0.0000128711,0.0002847697],"genre_scores_gemma":[0.003961027,0.9904112,0.0009251052,0.000005794164,0.0001441807,0.0001558459,0.0001163345,0.000112154,0.00416835],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6071534,"threshold_uncertainty_score":0.9998003,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3022131036","doi":"10.7554/elife.54870","title":"Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":661,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences; Economic and Social Research Council; Canadian Institute for Advanced Research; Medical Research Council; National Institute on Aging; Jacobs Foundation; Lundbeckfonden; Wellcome Trust","keywords":"Pace; Biomarker; Biological age; DNA methylation; Healthy aging; Cohort; Biology; Medicine; Bioinformatics; Gerontology; Internal medicine; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.04125398878145298,"gpt":0.2906202980546099,"spread":0.2493663092731569,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003137161,0.00007548804,0.0001062461,0.00001093198,0.00004372096,0.000005840615,0.000173719,0.00008766578,0.000004957455],"category_scores_gemma":[0.0004541014,0.00004623469,0.0000676268,0.0001817038,0.00008562709,0.000002976023,0.00007302024,0.00007260062,8.6855e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002993834,"about_ca_system_score_gemma":0.00002919431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002641784,"about_ca_topic_score_gemma":0.00001198818,"domain_scores_codex":[0.9992083,0.0001185917,0.0002665469,0.0001798204,0.0001364457,0.00009026907],"domain_scores_gemma":[0.9994333,0.00006151104,0.0001773387,0.0002284511,0.00008237178,0.00001702653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000574897,0.00004779416,0.02335464,0.000008197242,0.00001240921,1.068986e-7,0.0003588068,0.0002020103,0.9745601,0.0001602931,0.00003936907,0.001250489],"study_design_scores_gemma":[0.0002184803,0.0001287313,0.06007166,0.000008891169,0.00001421364,1.634545e-7,0.0001327685,0.0004810364,0.936833,0.000174176,0.001880632,0.0000562298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846506,0.002007215,0.01157302,0.001298857,0.00005316219,0.0001958465,0.00001623425,0.000004312784,0.0002007162],"genre_scores_gemma":[0.99786,0.0004822349,0.001343084,0.000143642,0.0001107378,0.000008202232,0.00002751189,0.000006944906,0.00001760707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03772712,"threshold_uncertainty_score":0.1885396,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011180717","doi":"10.1016/j.molcel.2005.12.007","title":"ING Tumor Suppressor Proteins Are Critical Regulators of Chromatin Acetylation Required for Genome Expression and Perpetuation","year":2006,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":654,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Chromatin; Acetylation; Epigenetics; Histone; Cell biology; Cell cycle; Chromatin remodeling; Helicase; DNA; Genetics; Cancer research; Cancer; Gene; RNA","retraction":null,"screen_n_in":null,"score":{"opus":0.007361827146455905,"gpt":0.2377627062011319,"spread":0.2304008790546759,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822421,0.0001267494,0.0001387626,0.00004952575,0.00007553492,0.00002249593,0.00006709575,0.0001202722,0.000005028276],"category_scores_gemma":[0.0001341563,0.0001311155,0.00006612108,0.00005278111,0.00006000877,0.000007268377,0.00005257224,0.00003605819,5.613762e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001109377,"about_ca_system_score_gemma":0.00002463194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000010574,"about_ca_topic_score_gemma":0.000003922593,"domain_scores_codex":[0.9990616,0.00006487493,0.0002713807,0.0002965126,0.0001411271,0.0001644876],"domain_scores_gemma":[0.9994177,0.00001872961,0.0001586225,0.0002244021,0.0001368954,0.00004360171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003989803,0.00005209406,0.0003939232,0.000132301,0.000003953232,0.000001032043,0.00003004901,0.0004679322,0.9986333,0.0001138171,0.00001862409,0.0001130838],"study_design_scores_gemma":[0.000529065,0.0001836114,0.00462879,0.00003074009,0.0000203318,8.058366e-7,0.00003036809,0.0008727482,0.9918485,0.0009048404,0.0008021743,0.0001480752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9088863,0.001564328,0.08870263,0.00006373598,0.00003417979,0.0004545107,0.00002565019,0.000008637885,0.0002599983],"genre_scores_gemma":[0.9842382,0.00001150976,0.01525597,0.00001742011,0.00008810416,0.00006120841,0.000230148,0.00002797397,0.00006945682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07535189,"threshold_uncertainty_score":0.5346733,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2579054962","doi":"10.1016/j.cmet.2016.12.011","title":"Serine Is an Essential Metabolite for Effector T Cell Expansion","year":2017,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":652,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Medical Research Council; Terry Fox Research Institute; Canada Foundation for Innovation","keywords":"Serine; Effector; Biology; Cell biology; T cell; Glycine; Serine hydroxymethyltransferase; Biochemistry; Immune system; Amino acid; Phosphorylation; Immunology","retraction":null,"screen_n_in":null,"score":{"opus":0.01321585532168183,"gpt":0.2811000500560864,"spread":0.2678841947344046,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002999651,0.0002232185,0.0002511645,0.00004128776,0.0003623799,0.0001372877,0.0003976348,0.0001963079,0.00003597731],"category_scores_gemma":[0.00005664792,0.0002093781,0.0001830476,0.000025079,0.00006244745,0.00001614737,0.0001443027,0.00006976278,0.00002221047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003376988,"about_ca_system_score_gemma":0.0000447258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003524365,"about_ca_topic_score_gemma":0.000009267268,"domain_scores_codex":[0.9987551,0.00006375867,0.0002216097,0.0005072408,0.0001418877,0.0003104258],"domain_scores_gemma":[0.9983985,0.00001051839,0.0002154539,0.00106658,0.0001475744,0.0001613123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007043878,0.00009913163,0.0002454783,0.00004340043,0.00001628004,6.326212e-7,0.00006219132,0.00001685313,0.9938526,0.00004342062,0.0003073272,0.005242223],"study_design_scores_gemma":[0.001011516,0.0001004646,0.006895954,0.000002093817,0.00007768986,2.848747e-7,0.000009942401,0.0001467717,0.7784228,0.0001881229,0.2129329,0.0002115309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827608,0.007037416,0.007180886,0.00007235898,0.001046135,0.0004112073,0.0001134347,0.00001450664,0.00136329],"genre_scores_gemma":[0.9890372,0.001121904,0.004659617,0.0001217845,0.001435181,0.00006193161,0.0003168259,0.00005387959,0.0031917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2154298,"threshold_uncertainty_score":0.8538193,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4313544615","doi":"10.1038/s41586-022-05580-6","title":"A DNA methylation atlas of normal human cell types","year":2023,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":627,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Leibniz-Gemeinschaft; Stichting Diabetes Onderzoek Nederland; Israel Science Foundation; Human Islet Research Network; National Institute of Diabetes and Digestive and Kidney Diseases; Hadassah Medical Organization; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"DNA methylation; Biology; Chromatin; Epigenetics; Epigenomics; CpG site; Genetics; Epigenetics of physical exercise; Methylation; Enhancer; Differentially methylated regions; Computational biology; Regulation of gene expression; DNA; Gene; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.007973071136316333,"gpt":0.2760977527922245,"spread":0.2681246816559082,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001401529,0.00006372581,0.00006686839,0.0000489059,0.00003862806,0.000005702689,0.00008009873,0.0005730591,0.00001970782],"category_scores_gemma":[0.00003617697,0.00006006792,0.00005070704,0.000148654,0.00001745053,0.000001698276,0.00004311263,0.0002078234,0.00001295446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003172302,"about_ca_system_score_gemma":0.00001723547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004796017,"about_ca_topic_score_gemma":0.0000134499,"domain_scores_codex":[0.9995266,0.00002595908,0.0001064145,0.0001374534,0.0001046286,0.00009896641],"domain_scores_gemma":[0.9996898,0.000006632168,0.0000584842,0.0001557448,0.00006446908,0.00002491446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009172792,0.00001255301,0.002038373,0.00001616206,0.000009179767,4.909277e-7,0.00003180156,0.0001703245,0.9955305,0.0001190238,0.001166772,0.0008956706],"study_design_scores_gemma":[0.0001677174,0.00009315722,0.03022728,0.000003135514,0.000008832909,1.337248e-7,0.00001004113,0.0000441587,0.9477443,0.0003666747,0.02126653,0.0000680694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920474,0.001432133,0.00009183517,0.00007160605,0.0001167173,0.00006338263,0.00001278444,0.00001215367,0.006151997],"genre_scores_gemma":[0.9974611,0.0001180954,0.0002024131,0.00002608102,0.0001518044,0.000002944902,0.0003260858,0.00001105757,0.001700416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04778621,"threshold_uncertainty_score":0.4419957,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2020016210","doi":"10.1016/j.molcel.2011.04.005","title":"Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells","year":2011,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":625,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institute on Drug Abuse; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; University of Pennsylvania","keywords":"Biology; Embryonic stem cell; Gene; Cell biology; Stem cell; Gene expression; Genome; Regulation of gene expression; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.007868205985788402,"gpt":0.193723213323455,"spread":0.1858550073376666,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001875634,0.0001646058,0.0001611812,0.00007287732,0.00002959975,0.000009483029,0.0001240902,0.0001856432,0.00001589368],"category_scores_gemma":[0.000008230695,0.0001720779,0.00005869558,0.00007686555,0.00005031592,0.000005221746,0.0001036998,0.00007021426,0.000003952715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001281648,"about_ca_system_score_gemma":0.00002311027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002541289,"about_ca_topic_score_gemma":0.000006349119,"domain_scores_codex":[0.998915,0.0001064551,0.0002727795,0.0003703916,0.0001326544,0.0002027651],"domain_scores_gemma":[0.9993334,0.000008145319,0.0001458497,0.0003804814,0.00004725203,0.00008486801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004640329,0.00009525647,0.002467314,0.0000333608,0.000007681351,0.000003862878,0.0001053669,0.0002316947,0.9966675,0.000002869757,0.00002861833,0.0003100678],"study_design_scores_gemma":[0.0005740005,0.000178465,0.00211551,0.000007662646,0.00001144253,4.310445e-7,0.00002604973,0.000113995,0.995551,0.00006757223,0.001169051,0.0001847887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843284,0.005574858,0.008845871,0.000007207354,0.00003662585,0.0002250249,0.00001920625,0.000006594125,0.0009562293],"genre_scores_gemma":[0.9966438,0.0004815689,0.001960255,0.00003868878,0.00001386294,0.00001175614,0.00009554562,0.00003346624,0.0007211042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01231537,"threshold_uncertainty_score":0.7017134,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2298824325","doi":"10.1073/pnas.1519286113","title":"Identification of tissue-specific cell death using methylation patterns of circulating DNA","year":2016,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":621,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Israel Science Foundation; Juvenile Diabetes Research Foundation International; Deutsche Forschungsgemeinschaft; Teva Pharmaceutical Industries","keywords":"Programmed cell death; DNA methylation; Pancreas; Cell type; Biology; Pathological; Pathology; Cell; Pancreatic cancer; Cancer research; Cancer; Medicine; Apoptosis; Endocrinology; Biochemistry; Gene expression; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.05474880091073432,"gpt":0.3213297548903827,"spread":0.2665809539796484,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001003105,0.00006145365,0.0001015369,0.00009322319,0.00005807865,0.000005600716,0.0002818769,0.00008028834,0.000004311082],"category_scores_gemma":[0.0002083444,0.00004101419,0.00005456912,0.0002035824,0.0001754601,0.00002455332,0.00006857873,0.00002769174,1.339783e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001204891,"about_ca_system_score_gemma":0.00002056691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004385495,"about_ca_topic_score_gemma":4.450303e-8,"domain_scores_codex":[0.998795,0.00001074436,0.000435351,0.0001791516,0.0005030322,0.00007670293],"domain_scores_gemma":[0.998663,0.00003763401,0.0008788909,0.00001506449,0.0003905076,0.00001489744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000005346133,0.00001965737,0.02308694,0.00004560022,0.000005445308,4.775433e-10,0.00004239189,0.0001809598,0.9740097,0.001720311,0.000002594877,0.0008810491],"study_design_scores_gemma":[0.0001068759,0.00003608747,0.0636382,0.00004832394,0.000008024684,3.70712e-7,0.00003761031,0.0002816327,0.9307777,0.004985538,0.00003448371,0.00004518257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983785,0.0002776204,0.0007530572,0.00009078968,0.00001740938,0.0001097783,0.00002080046,0.000001339934,0.0003506615],"genre_scores_gemma":[0.9983773,0.0001054794,0.001413074,0.000004905859,0.00004884066,0.00000179041,4.946183e-7,0.000004000181,0.00004412697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04323203,"threshold_uncertainty_score":0.167251,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2013785611","doi":"10.1038/nature10805","title":"Enhancer decommissioning by LSD1 during embryonic stem cell differentiation","year":2012,"lang":"en","type":"article","venue":"Nature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":614,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Human Genome Research Institute; Medical Research Council; Canadian Institutes of Health Research","keywords":"Enhancer; Biology; Chromatin; Cell biology; Demethylase; Histone; Cellular differentiation; Chromatin remodeling; Reprogramming; Transcription factor; Genetics; Cell; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.004034507270765506,"gpt":0.2424457868316482,"spread":0.2384112795608827,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008886204,0.0001017665,0.00006882679,0.00002080657,0.00009368033,0.00001772806,0.00008352903,0.0006918542,0.00003290674],"category_scores_gemma":[0.00001088087,0.00009261224,0.00004812347,0.00004781952,0.000007924916,0.000005410021,0.00005149996,0.0003713843,0.000009926554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001640325,"about_ca_system_score_gemma":0.00001167932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001029381,"about_ca_topic_score_gemma":0.000001675601,"domain_scores_codex":[0.9993892,0.0000369831,0.00009470481,0.0001621789,0.0001088004,0.0002081586],"domain_scores_gemma":[0.9996344,0.000006391487,0.00006687783,0.000176509,0.00003616851,0.0000796591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001132523,0.00003347108,0.008587894,0.00001600742,0.000008354737,7.657674e-8,0.00003968755,0.000009273293,0.9883832,0.000007879554,0.000918255,0.001984589],"study_design_scores_gemma":[0.0002176247,0.00002258752,0.01842674,0.000007193794,0.000009420072,4.379161e-7,0.0000189999,0.00001450211,0.9441694,0.00000909912,0.03698798,0.0001160238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9624283,0.03522248,0.0007101389,0.00005687362,0.00033722,0.00006846218,0.000007542396,0.00001027169,0.00115876],"genre_scores_gemma":[0.9953396,0.0005285958,0.0001813561,0.00005174426,0.0003368584,0.000006846693,0.0001352167,0.0000182154,0.003401618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0442138,"threshold_uncertainty_score":0.5336213,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1989421786","doi":"10.1038/ng1068","title":"DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells","year":2002,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":611,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Parks Canada","funders":"","keywords":"DNMT1; DNA methylation; Biology; Methylation; DNA methyltransferase; Gene silencing; Methyltransferase; Cancer research; CpG site; Tumor suppressor gene; Molecular biology; Cancer epigenetics; Cancer; Carcinogenesis; Gene expression; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01544785194000415,"gpt":0.2888930901438567,"spread":0.2734452382038526,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002335038,0.0001986537,0.0001716002,0.000117025,0.00008865441,0.00003472431,0.0001428465,0.0004791315,0.00006565636],"category_scores_gemma":[0.00003382664,0.0002089175,0.00004830635,0.0002009189,0.00003336434,0.000003692914,0.0001009947,0.0002241582,0.00000511882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004251198,"about_ca_system_score_gemma":0.00001997747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004848217,"about_ca_topic_score_gemma":0.0002304535,"domain_scores_codex":[0.9986517,0.00006553876,0.000288434,0.000491743,0.000197322,0.0003052414],"domain_scores_gemma":[0.9993487,0.00001202272,0.00008395028,0.0003333103,0.00009658421,0.000125408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001133638,0.0000282041,0.003294643,0.0000142478,0.00001614913,0.000002585003,0.0003062384,0.001136404,0.9866717,0.00001949978,0.0005415825,0.007957452],"study_design_scores_gemma":[0.0004305051,0.000172779,0.009112878,0.00001861671,0.00001882105,0.000001079948,0.00003515953,0.001017169,0.9800721,0.0004096107,0.008445429,0.0002658097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768552,0.02042037,0.001482493,0.0003484183,0.0002379462,0.0002782595,0.00003511191,0.000008906597,0.0003332492],"genre_scores_gemma":[0.9919408,0.003211123,0.003336665,0.0007183033,0.0003150625,0.0000329566,0.00003460911,0.00003475269,0.0003757599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01720924,"threshold_uncertainty_score":0.8519409,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2107766358","doi":"10.1038/ng.501","title":"Genome-wide association study identifies five loci associated with lung function","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":598,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Biocenter, University of Oulu; National Heart, Lung, and Blood Institute; NIHR Cambridge Biomedical Research Centre; Helmholtz Zentrum München; Wellcome Trust; Cancer Research UK; Asthma and Lung UK; Biotechnology and Biological Sciences Research Council; Medical Research Council; Directorate for Biological Sciences; National Institutes of Health; Oulun Yliopisto; European Commission; University of Bristol; Vetenskapsrådet; Healthway; British Lung Foundation; National Institute of Mental Health; International Osteoporosis Foundation; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; Genome Canada; British Heart Foundation; Scottish Government; AstraZeneca; Tays; King's College London; Juvenile Diabetes Research Foundation International","keywords":"Genome-wide association study; Biology; Genotyping; COPD; Vital capacity; Locus (genetics); Genetics; Pulmonary function testing; Genetic association; In silico; Lung function; Internal medicine; Bioinformatics; Single-nucleotide polymorphism; Genotype; Medicine; Lung; Gene; Diffusing capacity","retraction":null,"screen_n_in":null,"score":{"opus":0.004644334868257112,"gpt":0.2422298275555708,"spread":0.2375854926873137,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004152856,0.0002167513,0.0001801928,0.00007087391,0.0001582507,0.00008145276,0.0001635545,0.0005610208,0.00001186113],"category_scores_gemma":[0.0004336349,0.0002028623,0.00007199755,0.0002320355,0.00001754064,0.000006000031,0.00004107622,0.0003270236,0.000005570511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001057858,"about_ca_system_score_gemma":0.00006151073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002865593,"about_ca_topic_score_gemma":0.000183466,"domain_scores_codex":[0.9984672,0.000127468,0.0002517432,0.0004339052,0.0004219939,0.000297689],"domain_scores_gemma":[0.998861,0.00004089226,0.0002490871,0.0003399206,0.0004341858,0.00007497804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001847872,0.0005332387,0.8500711,0.000008347109,0.0004771647,0.000007138416,0.0003447384,0.002953118,0.1413707,0.000004560353,0.002778295,0.001266727],"study_design_scores_gemma":[0.0009057774,0.001371638,0.9612676,0.000007122683,0.0001765308,2.663597e-7,0.0001405304,0.00009084275,0.03196515,0.000241303,0.003543883,0.0002893746],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928009,0.004306128,0.001231667,0.0001617933,0.0002531033,0.0004555151,0.00001572599,0.00003106379,0.0007441259],"genre_scores_gemma":[0.9958677,0.0002704,0.000174479,0.0004378033,0.0003208729,0.00001164578,0.0005115853,0.00002705235,0.002378429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1111964,"threshold_uncertainty_score":0.8272483,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2061846271","doi":"10.1182/blood-2010-11-321208","title":"Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":597,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Ontario Institute for Cancer Research; University of Toronto; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Genomics; Terry Fox Foundation; GlaxoSmithKline; Ontario Innovation Trust; Deutsche Forschungsgemeinschaft; Ontario Genomics Institute; BC Cancer Foundation; Wellcome Trust; Leukemia and Lymphoma Society; Genome Canada; Pfizer","keywords":"EZH2; Biology; Histone H3; Histone methyltransferase; Molecular biology; PRC2; Methyltransferase; Histone; Methylation; Histone methylation; Mutation; Cancer research; DNA methylation; Genetics; Gene expression; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01067644703807115,"gpt":0.2680245912378236,"spread":0.2573481441997524,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000260301,0.0001823184,0.0002157147,0.00008118915,0.0001179996,0.00002015935,0.0001571231,0.000189708,0.00001990948],"category_scores_gemma":[0.000365074,0.0001828813,0.0001030007,0.0001786307,0.00004372172,0.00001257987,0.0001243506,0.00011044,0.00001875707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001610283,"about_ca_system_score_gemma":0.000141825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002136482,"about_ca_topic_score_gemma":0.0003708645,"domain_scores_codex":[0.998853,0.00009034283,0.0002732449,0.0003704536,0.0001859973,0.000226984],"domain_scores_gemma":[0.9990786,0.00006234776,0.0002015674,0.0004044948,0.0001460928,0.0001069265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006803522,0.0003530628,0.001289228,0.00002743507,0.00007680139,0.000001076891,0.0002704371,0.00002402918,0.9967928,0.0001328537,0.00001002894,0.0009542438],"study_design_scores_gemma":[0.0013068,0.0004004347,0.01130557,0.00001043396,0.000110543,0.000008094758,0.00001725255,0.0001221407,0.984229,0.002005135,0.0002823789,0.0002022286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912415,0.00009340444,0.00702305,0.00006510516,0.0001355327,0.0005220332,0.00005087438,0.0000158126,0.0008527254],"genre_scores_gemma":[0.9943562,0.00002706065,0.00503028,0.00002220834,0.0001458899,0.00005504809,0.0001349543,0.00003228534,0.0001961058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01256378,"threshold_uncertainty_score":0.7457683,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2138566050","doi":"10.1101/cshperspect.a000935","title":"Transcriptional Regulation by P53","year":2010,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":578,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; RNA polymerase II; Transcription factor; Chromatin; Gene; Mediator; Histone; Transcription (linguistics); Cell biology; Transcriptional regulation; Transcription preinitiation complex; Genetics; Regulation of gene expression; Promoter; Gene expression","retraction":null,"screen_n_in":null,"score":{"opus":0.02398937737902362,"gpt":0.3277406867659321,"spread":0.3037513093869085,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002999186,0.0003341225,0.0005998049,0.0001691829,0.00006336059,0.00002162669,0.0002826883,0.0009850293,0.00003844788],"category_scores_gemma":[0.0001266413,0.000327703,0.0002606932,0.000148999,0.0001764095,0.000003468841,0.0000692546,0.0004431795,0.00001322689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009507293,"about_ca_system_score_gemma":0.0001519229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001987464,"about_ca_topic_score_gemma":0.0000285005,"domain_scores_codex":[0.9982566,0.0001961189,0.000414935,0.000755439,0.0000783189,0.0002986292],"domain_scores_gemma":[0.9991882,0.00003959009,0.0001982431,0.0004304979,0.00007687009,0.00006652929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003660026,0.0002948752,0.0003722127,0.0008970829,0.0001998428,0.000002853869,0.00007906205,0.000006728697,0.8054124,0.0656372,0.0001294046,0.1269318],"study_design_scores_gemma":[0.0002079188,0.000103412,0.0003307563,0.0002243515,0.00005386111,5.836175e-7,0.000007726575,0.000004801094,0.002331794,0.0001070611,0.9962749,0.0003528613],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001790581,0.9956535,0.001183161,0.00002445524,0.0003992316,0.0004360223,0.00008506206,0.00001674771,0.0004112433],"genre_scores_gemma":[0.008765749,0.9895533,0.0006910014,0.00001082085,0.0004825465,0.0001155449,0.0001408281,0.00005513745,0.0001850811],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9961455,"threshold_uncertainty_score":0.9999175,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2560510482","doi":"10.1038/ng.3721","title":"Disease variants alter transcription factor levels and methylation of their binding sites","year":2016,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":564,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw","keywords":"Biology; DNA methylation; Genetics; Methylation; Single-nucleotide polymorphism; DNA binding site; CpG site; Expression quantitative trait loci; Quantitative trait locus; Differentially methylated regions; Transcription factor; CTCF; Genome-wide association study; Computational biology; Gene; Promoter; Gene expression; Genotype; Enhancer","retraction":null,"screen_n_in":null,"score":{"opus":0.02096819672398866,"gpt":0.2761229753333763,"spread":0.2551547786093877,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001219055,0.0001327713,0.0001094123,0.00005773005,0.00004190612,0.0000124652,0.00008341107,0.0002598727,0.00002007062],"category_scores_gemma":[0.00007882293,0.00009279436,0.00005683853,0.00006144634,0.00005470861,0.000005467573,0.00003412223,0.00007009562,0.000001360504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007870126,"about_ca_system_score_gemma":0.00003176003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.046917e-7,"about_ca_topic_score_gemma":0.000005147518,"domain_scores_codex":[0.9992243,0.00005757693,0.0001837676,0.000267126,0.0001255106,0.0001417239],"domain_scores_gemma":[0.9994642,0.00002474812,0.00009112681,0.0002251281,0.000106078,0.0000887539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003915305,0.00001788412,0.02126935,0.00001872674,0.00002528946,2.737088e-7,0.00004736714,0.000007845733,0.9608522,0.00003159348,0.00001503036,0.01767528],"study_design_scores_gemma":[0.0003507973,0.00009234847,0.1493774,0.0000176193,0.00002042367,3.65674e-7,0.0000065234,0.00004280357,0.8469135,0.0006772933,0.002379471,0.0001214629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825291,0.007926751,0.008790025,0.0001352319,0.0001615229,0.0001426006,0.0002559524,0.000006354248,0.00005248544],"genre_scores_gemma":[0.9970766,0.001222829,0.001265636,0.00003940502,0.0001657105,0.000003902723,0.00006269215,0.00001941571,0.0001437655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1281081,"threshold_uncertainty_score":0.3784044,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}