{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":405,"total_is_capped":false,"direct_labels_cover":1,"predictions_cover":405,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"02525cb222a6","filters":{"topic":"Histiocytic Disorders and Treatments"}},"results":[{"id":"W2295097092","doi":"10.1182/blood-2016-01-690636","title":"Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages","year":2016,"lang":"en","type":"review","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":1561,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute","keywords":"Histiocyte; Histiocytosis; Pathology; Hemophagocytic lymphohistiocytosis; Mucocutaneous zone; Medicine; Langerhans cell histiocytosis; Erdheim–Chester disease; Macrophage activation syndrome; Rosai–Dorfman disease; Phenotype; Biology; Disease","authors":[{"name":"Jean‐François Emile","is_ca":false},{"name":"Oussama Abla","is_ca":true},{"name":"Sylvie Fraitag","is_ca":false},{"name":"AnnaCarin Horne","is_ca":false},{"name":"Julien Haroche","is_ca":false},{"name":"Jean Donadieu","is_ca":false},{"name":"Luis Requena‐Caballero","is_ca":false},{"name":"Michael B. Jordan","is_ca":false},{"name":"Omar Abdel‐Wahab","is_ca":false},{"name":"Carl E. Allen","is_ca":false},{"name":"Frédéric Charlotte","is_ca":false},{"name":"Eli L. Diamond","is_ca":false},{"name":"R. Maarten Egeler","is_ca":true},{"name":"Alain Fischer","is_ca":false},{"name":"Juana Gil Herrera","is_ca":false},{"name":"Jan‐Inge Henter","is_ca":false},{"name":"Filip Jankú","is_ca":false},{"name":"Miriam Mérad","is_ca":false},{"name":"Jennifer Picarsic","is_ca":false},{"name":"Carlos Rodríguez‐Galindo","is_ca":false},{"name":"Barret J. Rollins","is_ca":false},{"name":"Abdellatif Tazi","is_ca":false},{"name":"Robert Vassallo","is_ca":false},{"name":"Lawrence M. Weiss","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02818478818619571,"gpt":0.298116358553177,"spread":0.2699315703669813,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007680778,0.0002061533,0.001024901,0.00007308428,0.00003572349,0.00000450335,0.000106587,0.0001555897,0.00006704046],"category_scores_gemma":[0.000130362,0.0001076001,0.0002628384,0.0001322601,0.0001670655,0.00001473999,0.00003674082,0.00009966891,0.00002286805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002861595,"about_ca_system_score_gemma":0.0002556034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007465528,"about_ca_topic_score_gemma":0.000001211901,"domain_scores_codex":[0.9989036,0.00007333505,0.0005029103,0.0002260921,0.0001805356,0.0001134727],"domain_scores_gemma":[0.9988064,0.0001496029,0.000460632,0.0004530997,0.0000750458,0.00005520582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001726431,0.001528438,0.000428174,0.06895659,0.0005369441,0.00002735172,0.00005774421,1.044578e-8,0.0001703899,0.0002937255,0.0004523731,0.927531],"study_design_scores_gemma":[0.004855497,0.0003496328,0.0008103108,0.04796436,0.01163837,0.0001338426,0.00001937305,0.000001284934,0.000643362,0.00003489063,0.9333134,0.0002356354],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001151432,0.9941009,0.000006308797,0.00002475988,0.00008473224,0.0007128172,0.0001197191,0.000009167645,0.003790175],"genre_scores_gemma":[0.008645372,0.9867746,0.0001435442,0.000007067705,0.00004493594,0.0000368263,0.00002761985,0.00003043703,0.004289635],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9328611,"threshold_uncertainty_score":0.4387805,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2069035104","doi":"10.1002/pbc.24367","title":"Langerhans cell histiocytosis (LCH): Guidelines for diagnosis, clinical work‐up, and treatment for patients till the age of 18 years","year":2012,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":686,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Universitaire Ziekenhuizen Leuven, KU Leuven; Association Histiocytose France; Johns Hopkins University; University Hospitals of Leicester NHS Trust; Karolinska Institutet; Newcastle University; Hospital for Sick Children; Histiocytosis Association","keywords":"Medicine; Langerhans cell histiocytosis; Blood cancer; Histiocytosis; Childhood cancer; Consensus conference; Pediatrics; Evidence-based practice; Intensive care medicine; Cancer; Family medicine; Pathology; Internal medicine; Alternative medicine; Disease","authors":[{"name":"Riccardo Haupt","is_ca":false},{"name":"Milen Minkov","is_ca":false},{"name":"Itziar Astigarraga","is_ca":false},{"name":"Eva Schäfer","is_ca":false},{"name":"Vasanta Nanduri","is_ca":false},{"name":"Rima Jubran","is_ca":false},{"name":"R. Maarten Egeler","is_ca":true},{"name":"Gritta Janka","is_ca":false},{"name":"Dragan Mićić","is_ca":false},{"name":"Carlos Rodríguez‐Galindo","is_ca":false},{"name":"Stefaan Van Gool","is_ca":false},{"name":"Johannes Visser","is_ca":false},{"name":"Sheila Weitzman","is_ca":true},{"name":"Jean Donadieu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1055601833109898,"gpt":0.3842427229725791,"spread":0.2786825396615892,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000157737,0.0001643295,0.0003757743,0.00005081877,0.00006482341,0.000007272771,0.00005913156,0.0000910164,0.0000614251],"category_scores_gemma":[0.0001964453,0.0001066245,0.0001972849,0.0001195212,0.00005281591,0.00003419197,0.00002081966,0.00004398446,0.000004366368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006103919,"about_ca_system_score_gemma":0.00009951802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002389737,"about_ca_topic_score_gemma":0.0000497791,"domain_scores_codex":[0.9989023,0.00002114831,0.0004200838,0.0002203957,0.0001509159,0.0002851589],"domain_scores_gemma":[0.9989313,0.0003701816,0.0001716511,0.0002075005,0.000191067,0.0001282746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002145225,0.001635837,0.9121914,0.0001091553,0.0001908675,9.66177e-7,0.0002859802,7.379692e-7,8.508801e-7,0.00000650664,0.05018071,0.03518246],"study_design_scores_gemma":[0.0251949,0.002319987,0.5041323,0.00007824181,0.01076193,0.000001367843,0.00009069347,0.00001626039,0.000163404,0.00003064778,0.4568873,0.0003229646],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748128,0.02180737,0.00003554931,0.0004188661,0.0007498576,0.001518307,0.0004083912,0.00001961269,0.0002292207],"genre_scores_gemma":[0.9758177,0.0167399,0.001649446,0.0004456427,0.00148549,0.001632042,0.000148144,0.00004046311,0.002041168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4080591,"threshold_uncertainty_score":0.434802,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2127524795","doi":"10.1046/j.1365-2559.2002.01418.x","title":"Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases","year":2002,"lang":"en","type":"article","venue":"Histopathology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":664,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Histiocyte; CD68; Histiocytic sarcoma; Pathology; S100 protein; Dendritic cell; Langerhans cell; Immunohistochemistry; Lymphoma; Follicular dendritic cells; Histiocytosis; Biology; Medicine; Antigen; T cell; Antigen-presenting cell; Immunology; Immune system; Disease","authors":[{"name":"Stefano Pileri","is_ca":false},{"name":"Thomas M. Grogan","is_ca":false},{"name":"Nancy L. Harris","is_ca":false},{"name":"Peter M. Banks","is_ca":false},{"name":"Elı́as Campo","is_ca":false},{"name":"John K. C. Chan","is_ca":false},{"name":"Riccardo Dalla Favera","is_ca":false},{"name":"Georges Delsol","is_ca":false},{"name":"Christiane De Wolf‐Peeters","is_ca":false},{"name":"Brunangelo Falini","is_ca":false},{"name":"R. D. Gascoyne","is_ca":true},{"name":"Philippe Gaulard","is_ca":false},{"name":"Kevin C. Gatter","is_ca":false},{"name":"P G Isaacson","is_ca":false},{"name":"Elaine S. Jaffe","is_ca":false},{"name":"P.M. Kluin","is_ca":false},{"name":"Dan Knowles","is_ca":false},{"name":"David Y. Mason","is_ca":false},{"name":"Shunsuke Mori","is_ca":false},{"name":"H‐K Müller‐Hermelink","is_ca":false},{"name":"Miguel Á. Piris","is_ca":false},{"name":"Elisabeth Ralfkiær","is_ca":false},{"name":"H. Stein","is_ca":false},{"name":"I‐J Su","is_ca":false},{"name":"Roger A. Warnke","is_ca":false},{"name":"Lawrence M. Weiss","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04930996441627916,"gpt":0.2818571400540263,"spread":0.2325471756377472,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001173984,0.0001414514,0.0002484339,0.0001026327,0.0001118787,0.00001435448,0.000172235,0.00006536469,0.00009058921],"category_scores_gemma":[0.0001381204,0.0001105378,0.00004313758,0.00008158037,0.0002209185,0.00003775914,0.00003047976,0.00007548959,0.00001884422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002614045,"about_ca_system_score_gemma":0.00003524169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002811846,"about_ca_topic_score_gemma":0.00002808877,"domain_scores_codex":[0.9989323,0.0001012927,0.0002485747,0.0003734614,0.0002141152,0.0001302582],"domain_scores_gemma":[0.9992182,0.0001654648,0.00008943123,0.0003863889,0.00005959358,0.00008098008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004624871,0.07188669,0.6298373,0.0001568304,0.0001568796,0.002051499,0.02559418,0.0001034744,0.1887569,0.003423005,0.01490301,0.05850539],"study_design_scores_gemma":[0.005553121,0.002153812,0.9790453,0.00004608498,0.000347453,0.0001811734,0.001775128,0.007989116,0.0005175694,0.00005332719,0.002121469,0.0002164015],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943359,0.000491638,0.0002776235,0.000315078,0.0002170128,0.0004254021,0.00004145283,0.00002837563,0.003867459],"genre_scores_gemma":[0.9978793,0.000009568605,0.00103326,0.0005559441,0.00005100072,0.0001080873,0.000110671,0.00001749924,0.0002346361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.349208,"threshold_uncertainty_score":0.4507602,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2802582740","doi":"10.1182/blood-2018-03-839753","title":"Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease","year":2018,"lang":"en","type":"review","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":624,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center; Hospital for Sick Children; American Society of Hematology","keywords":"Histiocyte; Medicine; Histiocytosis; Neuroblastoma RAS viral oncogene homolog; Rosai–Dorfman disease; Disease; Langerhans cell histiocytosis; Dermatology; Consensus conference; Pathology; KRAS; Intensive care medicine; Internal medicine; Cancer","authors":[{"name":"Oussama Abla","is_ca":true},{"name":"Eric D. Jacobsen","is_ca":false},{"name":"Jennifer Picarsic","is_ca":false},{"name":"Zdenka Křenová","is_ca":false},{"name":"Ronald Jaffe","is_ca":false},{"name":"Jean‐François Emile","is_ca":false},{"name":"Benjamin H. Durham","is_ca":false},{"name":"Jorge Braier","is_ca":false},{"name":"Frédéric Charlotte","is_ca":false},{"name":"Jean Donadieu","is_ca":false},{"name":"Fleur Cohen‐Aubart","is_ca":false},{"name":"Carlos Rodríguez‐Galindo","is_ca":false},{"name":"Carl E. Allen","is_ca":false},{"name":"James A. Whitlock","is_ca":true},{"name":"Sheila Weitzman","is_ca":true},{"name":"Kenneth L. McClain","is_ca":false},{"name":"Julien Haroche","is_ca":false},{"name":"Eli L. Diamond","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1621480870825569,"gpt":0.4446205446533409,"spread":0.282472457570784,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002019523,0.0001901289,0.0007644164,0.00004542138,0.00009537598,0.0000109484,0.00008246696,0.0000795442,0.00005041219],"category_scores_gemma":[0.0001229817,0.0001125969,0.0003940036,0.00008398071,0.0001951765,0.000006839898,0.0000562001,0.00007648709,0.00001848243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000160555,"about_ca_system_score_gemma":0.0001123547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009220214,"about_ca_topic_score_gemma":0.000005132167,"domain_scores_codex":[0.9989056,0.00005256053,0.0005287348,0.0002807853,0.0001003047,0.0001320306],"domain_scores_gemma":[0.9983908,0.0007968413,0.0002239049,0.0004071546,0.0000543773,0.0001269205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002630453,0.002093253,0.001206515,0.01219552,0.003645288,0.00003412071,0.00001082973,4.840105e-9,2.944948e-10,0.0005890956,0.01496637,0.9652327],"study_design_scores_gemma":[0.002317234,0.0002546023,0.000503346,0.008339317,0.03299383,0.000009838662,0.00002217265,0.000001966883,4.884226e-8,0.000100383,0.9553618,0.00009549325],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009097074,0.9959068,0.00001373235,0.000543363,0.0001931742,0.002271844,0.0004158238,0.00001579902,0.0005484493],"genre_scores_gemma":[0.00007852839,0.9963906,0.001423829,0.00005337673,0.00009910834,0.0007590068,0.0002245027,0.00002888873,0.0009421537],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9651372,"threshold_uncertainty_score":0.4591568,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2009347177","doi":"10.1182/blood-2012-09-455774","title":"Therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":450,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Histiocytosis; Chemotherapy; Immunology; Langerhans cell; Internal medicine; Antigen; Disease","authors":[{"name":"Helmut Gadner","is_ca":false},{"name":"Milen Minkov","is_ca":false},{"name":"Nicole Grois","is_ca":false},{"name":"Ulrike Pötschger","is_ca":false},{"name":"Elfriede Thiem","is_ca":false},{"name":"Maurizio Aricò","is_ca":false},{"name":"Itziar Astigarraga","is_ca":false},{"name":"Jorge Braier","is_ca":false},{"name":"Jean Donadieu","is_ca":false},{"name":"Jan‐Inge Henter","is_ca":false},{"name":"Gritta Janka‐Schaub","is_ca":false},{"name":"Kenneth L. McClain","is_ca":false},{"name":"Sheila Weitzman","is_ca":true},{"name":"Kevin Windebank","is_ca":false},{"name":"Stephan Ladisch","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01745170102691342,"gpt":0.2504116046467612,"spread":0.2329599036198477,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004705056,0.0001041809,0.0001900416,0.00007229955,0.00002863278,0.00001379804,0.00003839865,0.00006356419,0.00009830601],"category_scores_gemma":[0.00001722015,0.000079076,0.0000472956,0.00008921744,0.00001564353,0.00005745801,0.000007407935,0.00006441526,0.0002537149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004825851,"about_ca_system_score_gemma":0.00002437421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008036194,"about_ca_topic_score_gemma":0.00003891742,"domain_scores_codex":[0.9993413,0.00001907541,0.0002000505,0.0001664766,0.0001159727,0.000157132],"domain_scores_gemma":[0.9996635,0.00001831518,0.00005239314,0.0001700072,0.00003699625,0.0000588336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000351518,0.002804515,0.9515482,0.0001359376,0.00007688145,0.00004552335,0.0007765391,8.508875e-7,0.02370684,0.00002261836,0.0002452223,0.0206017],"study_design_scores_gemma":[0.02198137,0.0006611957,0.95787,0.00007677671,0.0001394185,0.00002058516,0.0002428957,0.0003016639,0.01687747,0.00006472855,0.001541179,0.000222695],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931775,0.0005418296,0.00001274833,0.0002539584,0.00005820326,0.0008752586,0.000003677155,0.00004950972,0.00502733],"genre_scores_gemma":[0.9964741,0.00003281686,0.0004454973,0.0001436167,0.00003289158,0.0002541212,0.00002517915,0.00001652857,0.002575221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02194622,"threshold_uncertainty_score":0.3261076,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2770975168","doi":"10.1001/jamaoncol.2017.5029","title":"Vemurafenib for <i>BRAF</i> V600–Mutant Erdheim-Chester Disease and Langerhans Cell Histiocytosis","year":2017,"lang":"en","type":"article","venue":"JAMA Oncology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":405,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Roche (Canada)","funders":"National Cancer Institute","keywords":"Vemurafenib; Medicine; V600E; Langerhans cell histiocytosis; Internal medicine; Progression-free survival; Melanoma; Oncology; Adverse effect; Positron emission tomography; Dermatology; Cancer research; Radiology; Chemotherapy; Disease; Mutation; Metastatic melanoma","authors":[{"name":"Eli L. Diamond","is_ca":false},{"name":"Vivek Subbiah","is_ca":false},{"name":"A. Craig Lockhart","is_ca":false},{"name":"Jean‐Yves Blay","is_ca":false},{"name":"Igor Puzanov","is_ca":false},{"name":"Ian Chau","is_ca":false},{"name":"Noopur Raje","is_ca":false},{"name":"Jürgen Wolf","is_ca":false},{"name":"Joseph P. Erinjeri","is_ca":false},{"name":"Jean Torrisi","is_ca":false},{"name":"Mario E. Lacouture","is_ca":false},{"name":"Elena Élez","is_ca":false},{"name":"Benjamin H. Durham","is_ca":false},{"name":"Maria E. Arcila","is_ca":false},{"name":"Gary A. Ulaner","is_ca":false},{"name":"Omar Abdel‐Wahab","is_ca":false},{"name":"Bethany Pitcher","is_ca":true},{"name":"Martina Makrutzki","is_ca":false},{"name":"Todd Riehl","is_ca":false},{"name":"José Baselga","is_ca":false},{"name":"David M. Hyman","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0307705264303714,"gpt":0.3246722442241393,"spread":0.2939017177937679,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001024276,0.0001653706,0.0003651594,0.00004924671,0.0003126628,0.00005447945,0.0001100964,0.0001496857,0.00008421057],"category_scores_gemma":[0.0002013403,0.0001358591,0.0001036864,0.00002007951,0.0001950639,0.00009742996,0.00006457149,0.0001044044,0.00006529544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001792757,"about_ca_system_score_gemma":0.0002305938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008693938,"about_ca_topic_score_gemma":0.00007665849,"domain_scores_codex":[0.9990714,0.00002334552,0.0001872261,0.0003253462,0.0001062063,0.0002865108],"domain_scores_gemma":[0.9988885,0.0001219812,0.0001465556,0.0004631882,0.00007062799,0.0003091822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007134652,0.005110798,0.1496293,0.001097482,0.0007688157,0.002796629,0.001889915,0.000002466601,0.006887501,0.00219223,0.0808091,0.7416811],"study_design_scores_gemma":[0.01590699,0.001433643,0.07934411,0.00007240094,0.0009927317,0.00006201601,0.0001109398,0.0002392779,0.0008826839,0.0008788519,0.8998377,0.0002386954],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.948798,0.0008388961,0.000211968,0.01731509,0.0004345622,0.0009195135,0.0001681944,0.00005569261,0.03125806],"genre_scores_gemma":[0.9897346,0.000161866,0.00111845,0.002346581,0.0002430956,0.0001911964,0.00006959761,0.00003051975,0.006104101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8190286,"threshold_uncertainty_score":0.5540173,"prediction_status":"machine_predicted_unvalidated"},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"split"},{"id":"W2079511675","doi":"10.1007/s00247-004-1262-0","title":"Langerhans? cell histiocytosis: pathology, imaging and treatment of skeletal involvement","year":2004,"lang":"en","type":"review","venue":"Pediatric Radiology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":348,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Eosinophilic granuloma; Skull; Pathology; Soft tissue; Histiocytosis; Metaphysis; Neuroradiology; Cranial vault; Anatomy; Disease","authors":[{"name":"E. Michel Azouz","is_ca":false},{"name":"Gaurav Saigal","is_ca":true},{"name":"Maria M. Rodríguez","is_ca":false},{"name":"Antonello Podda","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02577080050966428,"gpt":0.2976146311958829,"spread":0.2718438306862186,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008666379,0.0004743274,0.002271783,0.0003875912,0.00005213073,0.000004842709,0.00007976834,0.0002829942,0.00005574585],"category_scores_gemma":[0.00002274063,0.0003437471,0.0004083517,0.0001913035,0.000168928,0.00001949988,0.00003370363,0.0001347311,0.00004568852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006008376,"about_ca_system_score_gemma":0.0005718485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009912538,"about_ca_topic_score_gemma":0.000004304793,"domain_scores_codex":[0.998216,0.0001061357,0.0006534049,0.0005544095,0.0001142101,0.0003558489],"domain_scores_gemma":[0.9989156,0.000119465,0.0004056553,0.0003649504,0.00003818029,0.0001561817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002145986,0.001163668,0.003974273,0.01595114,0.0003614779,0.001107883,0.0002354736,4.649181e-7,5.682327e-7,0.00006770145,0.0004885458,0.9766273],"study_design_scores_gemma":[0.005328426,0.002149885,0.0003733858,0.0009474607,0.01444184,0.001864027,0.00005011589,0.000003126645,0.000001339137,0.00007784998,0.9742987,0.0004638441],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001472247,0.9961396,0.00002168196,0.00003252372,0.0002903074,0.0009848903,0.0001043227,0.00003774587,0.000916716],"genre_scores_gemma":[0.001092296,0.9968393,0.0004946601,0.00002236992,0.0003663386,0.0002257187,0.0004640571,0.00005045306,0.0004448428],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9761635,"threshold_uncertainty_score":0.9999015,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2104261840","doi":"10.1002/pbc.20246","title":"Uncommon histiocytic disorders: The non‐Langerhans cell histiocytoses","year":2004,"lang":"en","type":"review","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":311,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Histiocyte; Juvenile xanthogranuloma; Langerhans cell histiocytosis; Histiocytosis; Rosai–Dorfman disease; Medicine; Immunophenotyping; Pathology; Sinus Histiocytosis with Massive Lymphadenopathy; Dermatology; Disease; Immunology; Antigen","authors":[{"name":"Sheila Weitzman","is_ca":true},{"name":"Ronald Jaffe","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02311984253446864,"gpt":0.3170324429608383,"spread":0.2939126004263696,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001530872,0.0009554754,0.002199415,0.0003326593,0.0003113756,0.00006130118,0.0004756001,0.000467789,0.0006403229],"category_scores_gemma":[0.00005340169,0.0006049213,0.001031067,0.001017764,0.0001496173,0.00006782157,0.0001174064,0.0008245063,0.0004958885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001057874,"about_ca_system_score_gemma":0.003588833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001740836,"about_ca_topic_score_gemma":0.0002579444,"domain_scores_codex":[0.9967414,0.0000882214,0.0008877955,0.0008849379,0.0006498837,0.0007477969],"domain_scores_gemma":[0.997707,0.0002225718,0.0006316374,0.001039338,0.00009636676,0.0003030875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005338951,0.003294956,0.001889052,0.1131705,0.001745649,0.0003900896,0.0004338573,0.00002629346,8.500781e-8,0.000105402,0.01952727,0.8593634],"study_design_scores_gemma":[0.002978842,0.0002986474,0.00006833876,0.00441676,0.03872558,0.0000695718,0.00001875701,0.00000346943,4.5649e-7,0.00008323725,0.9527016,0.0006347712],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001152724,0.9875512,0.00002765459,0.0001758882,0.001049002,0.002144701,0.0002765416,0.0001359959,0.008523752],"genre_scores_gemma":[0.0009565362,0.9873995,0.0001635872,0.0001538385,0.001405229,0.001344954,0.000334833,0.0002009561,0.00804056],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9331743,"threshold_uncertainty_score":0.9996402,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2123420272","doi":"10.1016/j.ctrv.2010.02.012","title":"Langerhans cell histiocytosis: Current concepts and treatments","year":2010,"lang":"en","type":"review","venue":"Cancer Treatment Reviews","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":274,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; SickKids Foundation","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Malignancy; Histiocytosis; Immunotherapy; Salvage therapy; Disease; Immune system; Pathology; Immunology; Chemotherapy; Internal medicine","authors":[{"name":"Oussama Abla","is_ca":true},{"name":"R. Maarten Egeler","is_ca":false},{"name":"Sheila Weitzman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.11609083667682,"gpt":0.4510513757680648,"spread":0.3349605390912448,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008716989,0.001211253,0.00449239,0.000187962,0.0001570655,0.00004554074,0.0001310271,0.0003769481,0.0005524492],"category_scores_gemma":[0.00001610816,0.0007242393,0.0011108,0.0002561799,0.0001497862,0.00006120457,0.00004403687,0.0003608087,0.0006718906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001570754,"about_ca_system_score_gemma":0.0007770034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001615812,"about_ca_topic_score_gemma":0.00006378617,"domain_scores_codex":[0.9971259,0.0001462571,0.0009600146,0.001026031,0.000228828,0.0005129651],"domain_scores_gemma":[0.9978806,0.00006627275,0.0006422746,0.0008752156,0.00004779532,0.0004878593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001038337,0.0009512514,0.0001390493,0.01447625,0.0004831229,0.00006212418,0.00009159033,7.199984e-9,3.948126e-7,0.00000911891,0.002336259,0.9814404],"study_design_scores_gemma":[0.002514287,0.0005075943,0.00001090352,0.01937831,0.01929349,0.00006894877,0.000004779381,6.145725e-7,0.000003306073,0.000004419783,0.957746,0.0004673163],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002829764,0.9879268,0.000003306259,0.00003295935,0.0007598001,0.005344622,0.00041311,0.00007740631,0.005413742],"genre_scores_gemma":[0.000004197698,0.9812019,0.0002474006,0.00005513519,0.0003618457,0.00612919,0.001057396,0.0001209015,0.01082199],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9809731,"threshold_uncertainty_score":0.9995209,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1967246357","doi":"10.1002/pbc.20021","title":"Permanent consequences in Langerhans cell histiocytosis patients: A pilot study from the Histiocyte Society—Late Effects Study Group","year":2004,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":238,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Diabetes insipidus; Histiocytosis; Histiocyte; Pediatrics; Retrospective cohort study; Incidence (geometry); Disease; Surgery; Internal medicine; Pathology","authors":[{"name":"Riccardo Haupt","is_ca":false},{"name":"Vasanta Nanduri","is_ca":false},{"name":"Maria Grazia Calevo","is_ca":false},{"name":"Cecilia Bernstrand","is_ca":false},{"name":"Jorge Braier","is_ca":false},{"name":"Valerie Broadbent","is_ca":false},{"name":"Guadalupe Rey","is_ca":false},{"name":"Kenneth L. McClain","is_ca":false},{"name":"Gritta Janka‐Schaub","is_ca":false},{"name":"R. Maarten Egeler","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01343198507281703,"gpt":0.249889195202346,"spread":0.236457210129529,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001709377,0.000347432,0.0005040757,0.00008313009,0.0002057822,0.00003674924,0.0001997191,0.00005548579,0.00007999715],"category_scores_gemma":[0.00004338689,0.0002435064,0.0001201424,0.0004903472,0.00009118969,0.00007905326,0.00007052934,0.0002925264,0.00005620188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005625953,"about_ca_system_score_gemma":0.0003230023,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03791438,"about_ca_topic_score_gemma":0.005676241,"domain_scores_codex":[0.9978307,0.0001191477,0.0004351241,0.0006035283,0.0005947726,0.0004167175],"domain_scores_gemma":[0.9989983,0.0001787891,0.0001805847,0.0004086368,0.00008858504,0.0001450384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002414825,0.02257334,0.968223,0.00009401335,0.0003555306,0.0002071106,0.007036012,0.00005988551,0.00004241283,0.000002915658,0.000630693,0.0005335431],"study_design_scores_gemma":[0.03458897,0.008594736,0.9501043,0.00007767529,0.004634107,0.000001764985,0.0013119,0.000008840643,0.00004695632,0.00006862829,0.0002185147,0.0003436034],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887475,0.007135781,0.000006635919,0.0002891087,0.0004407324,0.002892984,0.00008935274,0.00007333977,0.0003245231],"genre_scores_gemma":[0.9966523,0.001092036,0.00007934413,0.0005216921,0.0003500763,0.0009556942,0.00005883833,0.00004251627,0.0002475074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03434749,"threshold_uncertainty_score":0.9929901,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2161616892","doi":"10.1136/adc.2008.144527","title":"Incidence and clinical features of Langerhans cell histiocytosis in the UK and Ireland","year":2008,"lang":"en","type":"article","venue":"Archives of Disease in Childhood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":207,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Incidence (geometry); Epidemiology; Pediatrics; Langerhans cell histiocytosis; Histiocytosis; Cancer registry; Disease; Pathology","authors":[{"name":"Jane A Salotti","is_ca":false},{"name":"Vasanta Nanduri","is_ca":false},{"name":"Mark S. Pearce","is_ca":false},{"name":"Louise Parker","is_ca":true},{"name":"Richard Lynn","is_ca":false},{"name":"Kevin Windebank","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01106209557141609,"gpt":0.2702386650632781,"spread":0.259176569491862,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006251431,0.00007973673,0.0002183509,0.0000816934,0.00002590482,0.000001925803,0.000058199,0.00002256077,0.000004660575],"category_scores_gemma":[0.0001211543,0.0000536993,0.00005054114,0.00006853849,0.0003013272,0.00001897811,0.00003102638,0.0001032421,3.978748e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004007738,"about_ca_system_score_gemma":0.00007807443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00024219,"about_ca_topic_score_gemma":0.000128141,"domain_scores_codex":[0.9993567,0.00005781236,0.0002223163,0.0001549022,0.0001151765,0.00009307286],"domain_scores_gemma":[0.9993538,0.000337818,0.00005785099,0.0001595301,0.000005729946,0.00008524512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002370851,0.0009587266,0.9917086,0.00006398305,0.00002004074,0.00008340386,0.003107638,0.000001318589,0.00001096601,0.00006145788,0.00005759137,0.003689176],"study_design_scores_gemma":[0.00271307,0.000224003,0.9957848,0.0001846239,0.00007739153,0.00001198661,0.0001539867,0.00001949528,0.00002256723,0.0007437899,0.00001845427,0.00004588971],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933032,0.003297645,0.000002786607,0.0003017105,0.00001053871,0.0002264394,0.00003072379,0.000002946092,0.002823958],"genre_scores_gemma":[0.9973227,0.002233414,0.0002514307,0.00010721,0.00001229952,0.000007262635,0.000013811,0.000005205355,0.0000466032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004076128,"threshold_uncertainty_score":0.2189794,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124794993","doi":"10.1002/gcc.22247","title":"<i>MAP2K1</i> and <i>MAP3K1</i> mutations in langerhans cell histiocytosis","year":2015,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":201,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Histiocytosis Association","keywords":"Trametinib; MAPK/ERK pathway; Biology; Protein kinase A; Mutation; Kinase; Cancer research; Somatic cell; Langerhans cell histiocytosis; Molecular biology; Genetics; Gene; Medicine; Pathology","authors":[{"name":"David Nelson","is_ca":false},{"name":"Astrid G. S. van Halteren","is_ca":false},{"name":"Willemijn T. Quispel","is_ca":false},{"name":"Cor van den Bos","is_ca":false},{"name":"Judith V.M.G. Bovée","is_ca":false},{"name":"Bhumi Patel","is_ca":false},{"name":"Gayane Badalian‐Very","is_ca":false},{"name":"Paul Van Hummelen","is_ca":false},{"name":"Matthew D. Ducar","is_ca":false},{"name":"Ling Lin","is_ca":false},{"name":"Laura E. MacConaill","is_ca":false},{"name":"R. Maarten Egeler","is_ca":true},{"name":"Barrett J. Rollins","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02321877149226033,"gpt":0.2733697518558874,"spread":0.2501509803636271,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004079625,0.0001185949,0.0002068491,0.00005957239,0.00004533405,0.00001664069,0.00002366026,0.00005201954,0.00006485204],"category_scores_gemma":[0.000005673786,0.0000998435,0.0000233778,0.000122525,0.00006892119,0.00005232487,0.00002270839,0.00005072463,0.00001103248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000940341,"about_ca_system_score_gemma":0.0001368591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008301362,"about_ca_topic_score_gemma":0.0004660551,"domain_scores_codex":[0.9993647,0.0000115042,0.0001268982,0.0002129979,0.0001162718,0.0001676773],"domain_scores_gemma":[0.9996398,0.00001340765,0.00003151436,0.0001052268,0.00003858174,0.0001714765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002620268,0.0008657313,0.6438473,0.0005811577,0.00019147,0.0003393506,0.00659784,0.00009216332,0.0050916,0.0002966244,0.01917879,0.3226559],"study_design_scores_gemma":[0.02662678,0.001150309,0.07371429,0.0004842272,0.0009093069,0.0002568427,0.004371724,0.001027495,0.01059289,0.001234574,0.878613,0.001018545],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9449891,0.046705,0.00001352188,0.001170746,0.0001261672,0.0002103274,0.00005066679,0.00002567596,0.006708834],"genre_scores_gemma":[0.9892377,0.006439794,0.0002873617,0.0006725474,0.00007641334,0.0001002726,0.00004102381,0.00001725571,0.003127606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8594342,"threshold_uncertainty_score":0.40715,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2166134395","doi":"10.1354/vp.43-5-632","title":"Canine Hemophagocytic Histiocytic Sarcoma: A Proliferative Disorder of CD11d+ Macrophages","year":2006,"lang":"en","type":"article","venue":"Veterinary Pathology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Histiocytic sarcoma; Histiocyte; Pathology; Sarcoma; Medicine; Biology","authors":[{"name":"Peter F. Moore","is_ca":false},{"name":"Verena K. Affolter","is_ca":false},{"name":"William Vernau","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01301531083194828,"gpt":0.2690738752498287,"spread":0.2560585644178804,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000773272,0.0002499329,0.0005585747,0.0001810345,0.00008374169,0.000005964753,0.00008537665,0.000118848,0.0002543076],"category_scores_gemma":[0.00003754677,0.0002130402,0.0001211045,0.0002239214,0.0002966577,0.00004943021,0.00006186465,0.000126989,0.00007770471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001344816,"about_ca_system_score_gemma":0.0001513047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002871084,"about_ca_topic_score_gemma":0.00002666859,"domain_scores_codex":[0.9986173,0.00008477434,0.0004051407,0.0003763067,0.0001721334,0.0003443498],"domain_scores_gemma":[0.9992846,0.00004897108,0.000135218,0.0003572352,0.00009364925,0.00008037543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0118158,0.02508538,0.3925443,0.003936312,0.001446105,0.1261875,0.00345791,0.000753992,0.3652646,0.02079446,0.008288139,0.04042547],"study_design_scores_gemma":[0.04947401,0.04391028,0.8107487,0.000539102,0.00176583,0.03875826,0.0006325454,0.003047201,0.008784077,0.004578707,0.03595581,0.001805476],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988185,0.002049819,0.0002751443,0.000214558,0.00013594,0.0004982265,0.00005351288,0.0000678549,0.00851994],"genre_scores_gemma":[0.993248,0.0000366532,0.001687342,0.0001238367,0.00006094103,0.00008935379,0.0001128497,0.00003727358,0.004603773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4182044,"threshold_uncertainty_score":0.8687527,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2041958591","doi":"10.1182/blood-2013-06-511139","title":"Somatic activating ARAF mutations in Langerhans cell histiocytosis","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":173,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Leids Universitair Medisch Centrum; Histiocytosis Association","keywords":"Vemurafenib; Langerhans cell histiocytosis; Cancer research; Somatic cell; Mutation; Exome sequencing; Biology; Exome; Genetics; Medicine; Internal medicine; Melanoma; Gene","authors":[{"name":"David Nelson","is_ca":false},{"name":"Willemijn T. Quispel","is_ca":false},{"name":"Gayane Badalian‐Very","is_ca":false},{"name":"Astrid G. S. van Halteren","is_ca":false},{"name":"Cor van den Bos","is_ca":false},{"name":"Judith V.M.G. Bovée","is_ca":false},{"name":"Sara Y. Tian","is_ca":false},{"name":"Paul Van Hummelen","is_ca":false},{"name":"Matthew Ducar","is_ca":false},{"name":"Laura E. MacConaill","is_ca":false},{"name":"R. Maarten Egeler","is_ca":true},{"name":"Barrett J. Rollins","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009873138923125727,"gpt":0.2357646111329434,"spread":0.2258914722098177,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005241581,0.00007669952,0.0001477793,0.00007813695,0.000043531,0.000007665651,0.00002928733,0.00003639067,0.00007471863],"category_scores_gemma":[0.00007452034,0.00006842364,0.00003537054,0.0001216354,0.00001644659,0.000029798,0.000005742187,0.00006190525,0.0001104911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003767306,"about_ca_system_score_gemma":0.00002833893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009896528,"about_ca_topic_score_gemma":0.00004570422,"domain_scores_codex":[0.9994841,0.00001909127,0.0001355636,0.0001247502,0.000101502,0.0001350211],"domain_scores_gemma":[0.9996844,0.00006588272,0.00004039951,0.0001387433,0.0000169675,0.00005360891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000981265,0.0201157,0.8386472,0.001334783,0.0004828308,0.0003916935,0.01389547,0.0001522041,0.04708228,0.001187199,0.0009059348,0.07570656],"study_design_scores_gemma":[0.08272963,0.002225041,0.7380503,0.001625665,0.002456114,0.0002092176,0.003237073,0.009212838,0.1388627,0.004961224,0.01502865,0.001401509],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9561225,0.00007056565,0.0001870355,0.0001700302,0.00002829677,0.0001545568,0.00000278326,0.00003957401,0.04322464],"genre_scores_gemma":[0.9966486,0.000005628578,0.002036058,0.00009029084,0.00003112887,0.00003672481,0.00003010492,0.00001290635,0.001108521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1005969,"threshold_uncertainty_score":0.2790235,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2531520225","doi":"10.1182/blood-2016-08-733790","title":"Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":169,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pediatric Oncology Group","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; Plexxikon; National Cancer Institute; National Institutes of Health; Lester and Sue Smith Foundation; Dan L. Duncan Cancer Center, Baylor College of Medicine; Howard Hughes Medical Institute; St. Baldrick's Foundation; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"MAPK/ERK pathway; Langerhans cell histiocytosis; Cancer research; Fusion gene; Mutation; V600E; Biology; Gene; Medicine; Genetics; Signal transduction; Pathology; Disease","authors":[{"name":"Rikhia Chakraborty","is_ca":true},{"name":"Thomas M. Burke","is_ca":true},{"name":"Oliver Hampton","is_ca":false},{"name":"Daniel Zinn","is_ca":true},{"name":"Karen Phaik Har Lim","is_ca":false},{"name":"Harshal Abhyankar","is_ca":false},{"name":"Brooks Scull","is_ca":false},{"name":"Vijetha Kumar","is_ca":false},{"name":"Nipun Kakkar","is_ca":false},{"name":"David A. Wheeler","is_ca":false},{"name":"Angshumoy Roy","is_ca":true},{"name":"Poulikos I. Poulikakos","is_ca":false},{"name":"Miriam Mérad","is_ca":false},{"name":"Kenneth L. McClain","is_ca":true},{"name":"D. Williams Parsons","is_ca":true},{"name":"Carl E. Allen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01079877551096688,"gpt":0.2289851962762662,"spread":0.2181864207652994,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002683772,0.00006717386,0.0001358122,0.00007956492,0.000009959195,0.000001448203,0.00003301809,0.00003594522,0.0001181233],"category_scores_gemma":[0.00002544461,0.00004559165,0.00003246661,0.00007375187,0.00001810701,0.00002572215,0.000009808938,0.00002267594,0.00003296408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004793373,"about_ca_system_score_gemma":0.00003219027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001879988,"about_ca_topic_score_gemma":0.0000240532,"domain_scores_codex":[0.999523,0.00001302184,0.0001258808,0.0001235186,0.0001191065,0.00009547722],"domain_scores_gemma":[0.9997277,0.00003072921,0.00005697802,0.0001189913,0.00003046073,0.0000351463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002228926,0.006687202,0.05856699,0.0001838878,0.0002835389,0.0001687041,0.001153985,0.000005556993,0.8919249,0.002640706,0.000185812,0.03797586],"study_design_scores_gemma":[0.01166896,0.0005301077,0.05113991,0.0002263118,0.0001669451,0.000008371533,0.00005909541,0.00001981886,0.932173,0.00379475,0.0001137641,0.00009899266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884711,0.00003811657,0.006335998,0.0001166727,0.00003485378,0.0001772964,0.000009866159,0.00001255561,0.004803558],"genre_scores_gemma":[0.9973642,0.00002695355,0.001524058,0.00004348905,0.00001619185,0.0000191503,0.000005196637,0.00001019433,0.0009906138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04024811,"threshold_uncertainty_score":0.1859173,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W992317070","doi":"10.1182/blood-2015-03-635151","title":"Cladribine and cytarabine in refractory multisystem Langerhans cell histiocytosis: results of an international phase 2 study","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":168,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Association Histiocytose France","keywords":"Cladribine; Medicine; Cytarabine; Internal medicine; Gastroenterology; Cytopenia; Refractory (planetary science); Langerhans cell histiocytosis; Toxicity; Surgery; Chemotherapy; Disease; Bone marrow","authors":[{"name":"Jean Donadieu","is_ca":false},{"name":"Frédéric Bernard","is_ca":false},{"name":"Max M. van Noesel","is_ca":false},{"name":"Mohamed Barkaoui","is_ca":false},{"name":"Odile Bardet","is_ca":false},{"name":"Rosamaria Mura","is_ca":false},{"name":"Maurizio Aricò","is_ca":false},{"name":"Christophe Piguet","is_ca":false},{"name":"Virginie Gandemer","is_ca":false},{"name":"Corinne Armari Alla","is_ca":false},{"name":"Niels Clausen","is_ca":false},{"name":"Éric Jeziorski","is_ca":false},{"name":"Anne Lambilliote","is_ca":false},{"name":"Sheila Weitzman","is_ca":true},{"name":"Jan‐Inge Henter","is_ca":false},{"name":"Cor van den Bos","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03326927811821148,"gpt":0.3170181235733548,"spread":0.2837488454551433,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001897027,0.0001016847,0.0002428096,0.0001253415,0.00001239077,0.000006050021,0.00005720227,0.00004397118,0.000008709281],"category_scores_gemma":[0.00008810948,0.00008611467,0.00001986177,0.00008227645,0.00002616143,0.00007872566,0.00002154722,0.00006914992,0.000006435337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006315835,"about_ca_system_score_gemma":0.00006838518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006411762,"about_ca_topic_score_gemma":0.0002280131,"domain_scores_codex":[0.9991058,0.00004375276,0.0003058715,0.0002218797,0.0002221463,0.0001005369],"domain_scores_gemma":[0.9994487,0.00001987695,0.0000953214,0.0002197591,0.00008653626,0.0001298432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.011044,0.2321472,0.6871173,0.0003406428,0.0009893576,0.003866801,0.025582,0.00002983416,0.01243689,0.0000399568,0.001041612,0.02536434],"study_design_scores_gemma":[0.7119953,0.02800446,0.2250775,0.0005521086,0.001495065,0.0001963472,0.01063233,0.00181914,0.009184344,0.00003528195,0.01040644,0.0006016254],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945344,0.0003135157,0.000003415737,0.00005539396,0.00008816581,0.0004074811,0.00008043661,0.00002156103,0.004495668],"genre_scores_gemma":[0.9988085,0.00002105116,0.0003296813,0.0000170525,0.00004741029,0.00002281302,0.0001248548,0.00001206445,0.0006165848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7009513,"threshold_uncertainty_score":0.3511654,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3209573575","doi":"10.1182/blood.2021013338","title":"ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; Children's Hospital of Eastern Ontario; University of Saskatchewan","funders":"Servier; Leids Universitair Medisch Centrum; National Cancer Institute; National Institutes of Health; Cincinnati Children's Hospital Medical Center; Universiteit Leiden; Cancer Research UK; Applebaum Foundation","keywords":"Anaplastic lymphoma kinase; Histiocyte; Histiocytosis; Pathology; Langerhans cell histiocytosis; Medicine; Disease","authors":[{"name":"Paul G. Kemps","is_ca":false},{"name":"Jennifer Picarsic","is_ca":false},{"name":"Benjamin H. Durham","is_ca":false},{"name":"Zofia Hélias‐Rodzewicz","is_ca":false},{"name":"Laura S. Hiemcke‐Jiwa","is_ca":false},{"name":"Cor van den Bos","is_ca":false},{"name":"Marianne D. van de Wetering","is_ca":false},{"name":"Carel J.M. van Noesel","is_ca":false},{"name":"Jan van Laar","is_ca":false},{"name":"Robert M. Verdijk","is_ca":false},{"name":"Uta Flucke","is_ca":false},{"name":"Pancras C.W. Hogendoorn","is_ca":false},{"name":"Feng Jung Sherida H. Woei-A-Jin","is_ca":false},{"name":"Raf Sciot","is_ca":false},{"name":"Friedrich Feuerhake","is_ca":false},{"name":"Martin Ebinger","is_ca":false},{"name":"Robert Möhle","is_ca":false},{"name":"Falko Fend","is_ca":false},{"name":"Antje Bornemann","is_ca":false},{"name":"Verena Wiegering","is_ca":false},{"name":"Karen Ernestus","is_ca":false},{"name":"Tina Méry","is_ca":false},{"name":"Olga Gryniewicz–Kwiatkowska","is_ca":false},{"name":"Bożenna Dembowska–Bagińska","is_ca":false},{"name":"D. A. Evseev","is_ca":false},{"name":"В. Г. Потапенко","is_ca":false},{"name":"V. V. Baykov","is_ca":false},{"name":"Stefania Gaspari","is_ca":false},{"name":"Sabrina Rossi","is_ca":false},{"name":"Marco Gessi","is_ca":false},{"name":"Gianpiero Tamburrini","is_ca":false},{"name":"Sébastien Héritier","is_ca":false},{"name":"Jean Donadieu","is_ca":false},{"name":"Jacinthe Bonneau‐Lagacherie","is_ca":false},{"name":"Claire Lamaison","is_ca":false},{"name":"Laure Farnault","is_ca":false},{"name":"Sylvie Fraitag","is_ca":false},{"name":"Marie‐Laure Jullié","is_ca":false},{"name":"Julien Haroche","is_ca":false},{"name":"Matthew Collin","is_ca":false},{"name":"Jackie Allotey","is_ca":false},{"name":"Majid Madni","is_ca":false},{"name":"Kerry Turner","is_ca":false},{"name":"Susan Picton","is_ca":false},{"name":"Pasquale Barbaro","is_ca":false},{"name":"Alysa Poulin","is_ca":true},{"name":"Ingrid S. Tam","is_ca":true},{"name":"Dina El Demellawy","is_ca":true},{"name":"Brianna Empringham","is_ca":true},{"name":"James A. Whitlock","is_ca":true},{"name":"Aditya Raghunathan","is_ca":false},{"name":"Amy A. Swanson","is_ca":false},{"name":"Mariko Suchi","is_ca":false},{"name":"Jon M. Brandt","is_ca":false},{"name":"Nabeel R. Yaseen","is_ca":false},{"name":"Joanna Weinstein","is_ca":false},{"name":"İrem Eldem","is_ca":false},{"name":"Bryan A. Sisk","is_ca":false},{"name":"Vaishnavi Sridhar","is_ca":false},{"name":"Mandy Atkinson","is_ca":false},{"name":"Lucas R. Massoth","is_ca":false},{"name":"Jason L. Hornick","is_ca":false},{"name":"Sanda Alexandrescu","is_ca":false},{"name":"Kee Kiat Yeo","is_ca":false},{"name":"Kseniya Petrova‐Drus","is_ca":false},{"name":"Stephen Peeke","is_ca":false},{"name":"Laura Muñoz-Arcos","is_ca":false},{"name":"Daniel Leino","is_ca":false},{"name":"David D. Grier","is_ca":false},{"name":"Robert B. Lorsbach","is_ca":false},{"name":"Somak Roy","is_ca":false},{"name":"Shipra Garg","is_ca":false},{"name":"Nishant Tiwari","is_ca":false},{"name":"Kristian T. Schafernak","is_ca":false},{"name":"M M Henry","is_ca":false},{"name":"Astrid G. S. van Halteren","is_ca":false},{"name":"Oussama Abla","is_ca":true},{"name":"Eli L. Diamond","is_ca":false},{"name":"Jean‐François Emile","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02434983270436161,"gpt":0.2731335024151223,"spread":0.2487836697107607,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001447458,0.0001835236,0.0003116717,0.0001014253,0.0001257594,0.00003441776,0.00003197468,0.00008646362,0.00008075872],"category_scores_gemma":[0.000337099,0.0001594676,0.00007216258,0.00022208,0.00004206175,0.00004499568,0.0000889679,0.0001241954,0.00007287011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000532456,"about_ca_system_score_gemma":0.0001971619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007355159,"about_ca_topic_score_gemma":0.00004851563,"domain_scores_codex":[0.9986538,0.0001039344,0.0002872182,0.0004963749,0.0001879614,0.00027077],"domain_scores_gemma":[0.9992902,0.0001009618,0.0000770303,0.000238686,0.00005786991,0.0002352695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00677733,0.02372317,0.6759748,0.0006596388,0.001567692,0.06713536,0.00982962,0.0000203999,0.1464281,0.006898677,0.01308219,0.04790298],"study_design_scores_gemma":[0.04271774,0.01632546,0.6888979,0.001069107,0.004062087,0.003669289,0.001398808,0.00005532169,0.2111818,0.005935929,0.02345876,0.001227853],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985051,0.001570244,0.0001297483,0.009064169,0.0001071801,0.0003884651,0.00001880285,0.00008625632,0.003584126],"genre_scores_gemma":[0.990198,0.0001962481,0.002317108,0.004668073,0.0001240263,0.00003605736,0.00005686975,0.00001901256,0.002384603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06475362,"threshold_uncertainty_score":0.6502899,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1990412304","doi":"10.1097/mop.0b013e3282f45ba4","title":"Langerhans cell histiocytosis: update for the pediatrician","year":2008,"lang":"en","type":"review","venue":"Current Opinion in Pediatrics","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":146,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Disease; Histiocytosis; Etiology; Histiocyte; Intensive care medicine; Pediatrics; Pathology","authors":[{"name":"Sheila Weitzman","is_ca":true},{"name":"R. Maarten Egeler","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1118962498753786,"gpt":0.3970625473982042,"spread":0.2851662975228256,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001555191,0.0005390501,0.001331993,0.0005119301,0.0001815165,0.00002809904,0.0003060267,0.0003187107,0.00003594435],"category_scores_gemma":[0.0001601575,0.0003589254,0.000773112,0.0008871536,0.00005931147,0.00004412734,0.00007397533,0.0005747922,0.0002399089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004539699,"about_ca_system_score_gemma":0.001078478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001343106,"about_ca_topic_score_gemma":0.000001844516,"domain_scores_codex":[0.9976261,0.0000646125,0.0008580543,0.0005628601,0.0004002782,0.0004880881],"domain_scores_gemma":[0.9981945,0.0005098491,0.0004600709,0.0005643764,0.0001055892,0.0001655796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001602642,0.0006762606,0.0002601057,0.02825019,0.00004011553,0.000005442321,0.00006634286,0.000001407249,4.88628e-10,0.00006124042,0.1723775,0.7982453],"study_design_scores_gemma":[0.001393114,0.0001185253,0.00001649059,0.001498533,0.001562871,0.00002915373,0.00001530946,0.00002565636,1.155137e-8,0.00001829047,0.995003,0.0003189968],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000001323694,0.9873362,0.0003473512,0.00007936187,0.008639153,0.00270131,0.0004749201,0.00005852268,0.0003618867],"genre_scores_gemma":[0.000003748776,0.9926918,0.0001699423,0.0000206443,0.003830701,0.0009741875,0.001864151,0.0000922965,0.0003525364],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8226255,"threshold_uncertainty_score":0.9998863,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1769545231","doi":"10.1002/pbc.25017","title":"Updates on histiocytic disorders","year":2014,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Medicine; Histiocyte; Hemophagocytic lymphohistiocytosis; Langerhans cell histiocytosis; Blood cancer; Histiocytosis; Hematology; Disease; Rosai–Dorfman disease; Cancer; Malignant histiocytosis; Rare disease; Pathology; Immunology; Internal medicine","authors":[{"name":"Sarah R. Vaiselbuh","is_ca":false},{"name":"Yenan T. Bryceson","is_ca":false},{"name":"Carl E. Allen","is_ca":false},{"name":"James A. Whitlock","is_ca":true},{"name":"Oussama Abla","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006082887544727716,"gpt":0.2514721183204458,"spread":0.2453892307757181,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006887377,0.0001935002,0.0002713369,0.0001264765,0.0000971657,0.00001388076,0.00007722967,0.00007286629,0.0007041036],"category_scores_gemma":[0.00007469657,0.0001584201,0.0001036393,0.000251343,0.00003927878,0.00003643529,0.00001793953,0.0001339043,0.0003694989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008127719,"about_ca_system_score_gemma":0.0001413091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003307444,"about_ca_topic_score_gemma":0.0000786678,"domain_scores_codex":[0.998872,0.00002160368,0.0001930956,0.0003344288,0.0002737755,0.0003050306],"domain_scores_gemma":[0.9993538,0.00006444677,0.00007334491,0.0002951984,0.00004110129,0.0001721694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002969824,0.002891547,0.8771475,0.0005173034,0.0004709689,0.00004002898,0.0002918766,0.0001581947,0.00002820506,0.004764806,0.040581,0.0728116],"study_design_scores_gemma":[0.047019,0.005608767,0.3964687,0.000303403,0.01412682,0.00005595924,0.00009566153,0.002100651,0.0005376514,0.00781639,0.5238455,0.002021454],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.947947,0.004104355,0.000120209,0.001811554,0.0006679048,0.0004258751,0.00002701576,0.0001710862,0.04472503],"genre_scores_gemma":[0.9923667,0.002128274,0.0002098004,0.0009705467,0.000745929,0.0001079426,0.00003040647,0.00003672044,0.003403687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4832645,"threshold_uncertainty_score":0.7709441,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2078626081","doi":"10.1016/j.jpeds.2008.05.002","title":"Reactivations in Multisystem Langerhans Cell Histiocytosis: Data of the International LCH Registry","year":2008,"lang":"en","type":"article","venue":"The Journal of Pediatrics","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Context (archaeology); Histiocytosis; Retrospective cohort study; Disease; Pediatrics; Internal medicine","authors":[{"name":"Milen Minkov","is_ca":false},{"name":"Manuel Steiner","is_ca":false},{"name":"Ulrike Pötschger","is_ca":false},{"name":"Maurizio Aricò","is_ca":false},{"name":"Jorge Braier","is_ca":false},{"name":"Jean Donadieu","is_ca":false},{"name":"Nicole Grois","is_ca":false},{"name":"Jan‐Inge Henter","is_ca":false},{"name":"Gritta Janka","is_ca":false},{"name":"Kenneth L. McClain","is_ca":false},{"name":"Sheila Weitzman","is_ca":true},{"name":"Kevin Windebank","is_ca":false},{"name":"Stephan Ladisch","is_ca":false},{"name":"Helmut Gadner","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05797719139960438,"gpt":0.2842653459637862,"spread":0.2262881545641818,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003230292,0.00006117638,0.0001521299,0.0000893766,0.00005307427,0.00000311975,0.0004393116,0.00003776501,0.00001233394],"category_scores_gemma":[0.0003149523,0.00003299112,0.00004951552,0.0002131717,0.00004817233,0.00007325326,0.00007263324,0.0001984149,0.000003568245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001258322,"about_ca_system_score_gemma":0.0003073102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001488712,"about_ca_topic_score_gemma":0.00003282686,"domain_scores_codex":[0.9990838,0.00004267827,0.0003571346,0.00005905942,0.0003837383,0.0000735969],"domain_scores_gemma":[0.9988422,0.0001419177,0.000442231,0.0003943805,0.0001460393,0.00003324143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004922851,0.001988384,0.8780738,0.000263157,0.0001109313,0.0002316071,0.004130257,0.0003296408,0.002188233,0.00009183027,0.1108879,0.001212005],"study_design_scores_gemma":[0.0224798,0.0007628579,0.9162225,0.0006606253,0.003211948,0.004287316,0.005745967,0.001590353,0.003692943,0.0003034895,0.04057928,0.0004629312],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924495,0.001019604,0.0001705564,0.001495572,0.00039549,0.00012338,0.00005286486,0.000003196911,0.004289876],"genre_scores_gemma":[0.9971594,0.001062241,0.0003142146,0.00006270636,0.0002332118,7.426992e-7,0.00001056569,0.000006834249,0.001150148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0703086,"threshold_uncertainty_score":0.1345339,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2039618433","doi":"10.1002/ijc.11004","title":"Childhood cancer registries in Ontario, Canada: Lessons learned from a comparison of two registries","year":2003,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; McMaster University Medical Centre; Pediatric Oncology Group","funders":"University of Toronto","keywords":"Cancer registry; Medicine; Pediatrics; Cancer; Incidence (geometry); Medical diagnosis; Population; Family medicine; Pathology; Environmental health; Internal medicine","authors":[{"name":"Mark Greenberg","is_ca":true},{"name":"Ronald D. Barr","is_ca":true},{"name":"Bruna DiMonte","is_ca":true},{"name":"Eva McLaughlin","is_ca":true},{"name":"Corin Greenberg","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05349409845651917,"gpt":0.3727096897882942,"spread":0.319215591331775,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007320035,0.0001080685,0.0003862694,0.00009944766,0.00002122951,0.0000133517,0.0001368331,0.00003562581,0.0009952519],"category_scores_gemma":[0.0001244938,0.00009105643,0.00007895618,0.00007741794,0.00006343494,0.00007149125,0.00001150192,0.0002397738,5.836457e-7],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001592801,"about_ca_system_score_gemma":0.006118215,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9658987,"about_ca_topic_score_gemma":0.9938042,"domain_scores_codex":[0.9986478,0.00002513192,0.0005068589,0.000114367,0.0005878848,0.000117972],"domain_scores_gemma":[0.9988855,0.00005619317,0.0004958886,0.00009616095,0.0003896005,0.00007666468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005274836,0.000441823,0.9723716,0.000006453689,0.001103331,0.0002054638,0.001455707,0.0008445928,0.0001102121,0.00113619,0.008055801,0.01374135],"study_design_scores_gemma":[0.01366886,0.0001907038,0.745292,0.001265818,0.0003941407,0.0000571609,0.001009987,0.00003530559,0.005048749,0.002706497,0.2301345,0.0001962278],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830876,0.006190056,0.00005823397,0.006353875,0.0009639933,0.00007791245,0.00009683457,0.00000241354,0.003169096],"genre_scores_gemma":[0.9976791,0.0004897417,0.0002176689,0.0002025216,0.00008579926,0.000006971897,0.00001350084,0.00000944302,0.00129521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2270796,"threshold_uncertainty_score":0.999918,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2027889680","doi":"10.1002/pbc.22229","title":"2′‐chlorodeoxyadenosine (2‐CdA) as salvage therapy for Langerhans cell histiocytosis (LCH). results of the LCH‐S‐98 protocol of the histiocyte society","year":2009,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Histiocyte; Histiocytosis; Salvage therapy; Surgery; Internal medicine; Gastroenterology; Disease; Chemotherapy; Pathology","authors":[{"name":"Sheila Weitzman","is_ca":true},{"name":"Jorge Braier","is_ca":false},{"name":"Jean Donadieu","is_ca":false},{"name":"R. Maarten Egeler","is_ca":false},{"name":"Nicole Grois","is_ca":false},{"name":"Stephan Ladisch","is_ca":false},{"name":"Ulrike Pötschger","is_ca":false},{"name":"David C. Webb","is_ca":false},{"name":"James A. Whitlock","is_ca":false},{"name":"R.J. Arceci","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01399810976776813,"gpt":0.2879838772006084,"spread":0.2739857674328403,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002154134,0.0002855494,0.0005007765,0.00005165445,0.0001866132,0.00001041544,0.0003289033,0.000163971,0.00009810534],"category_scores_gemma":[0.00009137508,0.0001638247,0.0005551649,0.0005523356,0.0001332875,0.0000481302,0.00004144226,0.000205718,0.000003812376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001496356,"about_ca_system_score_gemma":0.0007693761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00105206,"about_ca_topic_score_gemma":0.00005997071,"domain_scores_codex":[0.9980351,0.00005075181,0.0005954054,0.0003973721,0.0005719468,0.0003494691],"domain_scores_gemma":[0.9982353,0.000112717,0.0005861483,0.0006999274,0.0002737817,0.0000920993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01492108,0.02501159,0.2524791,0.00625101,0.002761514,0.00003406029,0.01533481,0.0004732428,0.02590773,0.0005668266,0.5976621,0.05859689],"study_design_scores_gemma":[0.1415889,0.00833683,0.2913299,0.0008699917,0.01196301,0.00004966678,0.000707545,0.0004122784,0.2273882,0.001286261,0.3144706,0.00159691],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.855738,0.01032311,0.0001024334,0.008860323,0.0008612599,0.1113625,0.000987369,0.0001371346,0.01162778],"genre_scores_gemma":[0.9722586,0.001021945,0.0005358918,0.001215956,0.0006957867,0.01686615,0.00002061106,0.00005021587,0.007334809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2831915,"threshold_uncertainty_score":0.6680579,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2756862815","doi":"10.1002/pbc.26784","title":"Evaluation and treatment of Langerhans cell histiocytosis patients with central nervous system abnormalities: Current views and new vistas","year":2017,"lang":"en","type":"review","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"St. Baldrick's Foundation","keywords":"Medicine; Langerhans cell histiocytosis; Choroid plexus; Central nervous system; Cerebrum; Magnetic resonance imaging; Pons; Cerebellum; Pathology; Basal ganglia; Histiocytosis; Radiology; Anatomy; Disease; Internal medicine","authors":[{"name":"E. Ann Yeh","is_ca":true},{"name":"Jay Greenberg","is_ca":false},{"name":"Oussama Abla","is_ca":true},{"name":"Giulia Longoni","is_ca":true},{"name":"Eli L. Diamond","is_ca":false},{"name":"Michelle L. Hermiston","is_ca":false},{"name":"Brandon Tran","is_ca":false},{"name":"Carlos Rodríguez‐Galindo","is_ca":false},{"name":"Carl E. Allen","is_ca":false},{"name":"Kenneth L. McClain","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1089634494752405,"gpt":0.3625666259293076,"spread":0.2536031764540672,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001087754,0.0004937339,0.00169485,0.0001710985,0.0001156871,0.00003603987,0.00007201508,0.0001408878,0.0000505235],"category_scores_gemma":[0.00001625769,0.0003232361,0.0001861545,0.0001163366,0.00005384059,0.00006113888,0.00002474483,0.0000970304,0.000004648069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006441778,"about_ca_system_score_gemma":0.001651296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001537897,"about_ca_topic_score_gemma":0.0001555668,"domain_scores_codex":[0.9979863,0.00009454138,0.0005471427,0.0004886045,0.0005629276,0.0003205286],"domain_scores_gemma":[0.9982604,0.00004680489,0.0007988304,0.0004059151,0.0001889383,0.0002990614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003928871,0.0006406595,0.01669329,0.02507728,0.0005314149,0.00001017666,0.000340711,3.809214e-7,4.509936e-9,0.000003258633,0.0003016795,0.9563618],"study_design_scores_gemma":[0.009791848,0.001433981,0.005783469,0.006791879,0.09211583,0.00002060663,0.00003289603,0.00001101799,4.480733e-7,0.000001381815,0.883576,0.0004406742],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007653506,0.9882794,0.000003788747,0.0000055839,0.0003191862,0.002477825,0.0005494763,0.00002234725,0.0006889076],"genre_scores_gemma":[0.003778532,0.9941888,0.00006040162,0.000002968776,0.0005065991,0.0004483453,0.0004065548,0.00005220373,0.0005556304],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9559212,"threshold_uncertainty_score":0.999922,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2158332141","doi":"10.1002/pbc.20479","title":"Cutaneous Langerhans cell histiocytosis in children under one year","year":2005,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Histiocytosis Association","keywords":"Medicine; Langerhans cell histiocytosis; Histiocytosis; Incidence (geometry); Disease; Dermatology; Retrospective cohort study; Pediatrics; Surgery; Pathology","authors":[{"name":"Loretta M. S. Lau","is_ca":true},{"name":"Bernice R. Krafchik","is_ca":true},{"name":"Monika Trebo","is_ca":false},{"name":"Sheila Weitzman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00876582203288006,"gpt":0.2373931678408771,"spread":0.228627345807997,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003540875,0.0001578633,0.0002634295,0.0001530305,0.0000400745,0.00001012034,0.00006990742,0.00009418753,0.001106618],"category_scores_gemma":[0.000009430474,0.0001501269,0.00007190293,0.0002951482,0.00002193311,0.00003973617,0.00002116963,0.0001560104,0.0003079678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001974116,"about_ca_system_score_gemma":0.0001962672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001252833,"about_ca_topic_score_gemma":0.0003622475,"domain_scores_codex":[0.9989805,0.00001357631,0.00021014,0.0002495119,0.0002408933,0.0003053412],"domain_scores_gemma":[0.9995456,0.00002030938,0.00006118697,0.0002094562,0.00003260317,0.0001308919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006646679,0.001742467,0.9900777,0.00006339271,0.000129315,0.00002951159,0.0002456509,0.0001264158,0.00005529798,0.00003361805,0.003272343,0.00415778],"study_design_scores_gemma":[0.03493846,0.001116725,0.9309593,0.000161867,0.008898363,0.0002848714,0.0002287652,0.0001587936,0.002309704,0.0002305925,0.01928686,0.001425634],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816356,0.007619804,0.00001169026,0.0006587747,0.00007746668,0.0003314642,0.00005091188,0.0000610271,0.009553224],"genre_scores_gemma":[0.9897795,0.003752794,0.0005331598,0.0005040028,0.0008636129,0.00006452447,0.00003856857,0.00003465925,0.004429156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05911838,"threshold_uncertainty_score":0.9998065,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1744607539","doi":"10.1182/blood-2015-01-620377","title":"Sirolimus plus prednisone for Erdheim-Chester disease: an open-label trial","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Workers Compensation Board of British Columbia","funders":"","keywords":"Erdheim–Chester disease; Prednisone; Sirolimus; Medicine; Histiocyte; PI3K/AKT/mTOR pathway; Histiocytosis; Internal medicine; Disease; Pathology; Chemistry; Signal transduction","authors":[{"name":"Davide Gianfreda","is_ca":false},{"name":"Maria Nicastro","is_ca":false},{"name":"Maricla Galetti","is_ca":true},{"name":"Federico Alberici","is_ca":false},{"name":"Domenico Corradi","is_ca":false},{"name":"G Becchi","is_ca":false},{"name":"Giorgio Baldari","is_ca":false},{"name":"Massimo De Filippo","is_ca":false},{"name":"Stefania Ferretti","is_ca":false},{"name":"Gabriella Moroni","is_ca":false},{"name":"Rosario Foti","is_ca":false},{"name":"Marcella Di Gangi","is_ca":false},{"name":"Guido Jeannin","is_ca":false},{"name":"Raphaël Saffroy","is_ca":false},{"name":"Jean‐François Emile","is_ca":false},{"name":"Carlo Buzio","is_ca":false},{"name":"Augusto Vaglio","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1382107749685668,"gpt":0.3699909789274466,"spread":0.2317802039588798,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001280421,0.0001484478,0.0002995036,0.00003550392,0.000067655,0.00005848605,0.0001506597,0.00006266221,0.00003202902],"category_scores_gemma":[0.000149662,0.0001200118,0.00004034471,0.00006572144,0.00003779484,0.0001384845,0.00005916525,0.00004829088,0.00006312925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005443092,"about_ca_system_score_gemma":0.0004899297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004202509,"about_ca_topic_score_gemma":0.00001321987,"domain_scores_codex":[0.9990315,0.00002391612,0.0001936929,0.0003013191,0.0002080062,0.0002415848],"domain_scores_gemma":[0.9988911,0.00002667988,0.0000553464,0.0003998567,0.00008696177,0.0005400539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6653758,0.1843148,0.01228136,0.0008252965,0.004139196,0.001718174,0.005337884,0.00002565431,0.000549058,0.004727819,0.05956629,0.06113874],"study_design_scores_gemma":[0.9367578,0.00951827,0.001242011,0.00006979235,0.002177755,0.00002440362,0.0001359719,0.0005682867,0.0001131945,0.001470756,0.04764421,0.0002775229],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882873,0.0009116801,0.0001698021,0.000610261,0.0003250228,0.003149548,0.0001155128,0.00007960061,0.006351281],"genre_scores_gemma":[0.9870098,0.00001124373,0.002839371,0.0004510035,0.0004037291,0.0005359467,0.0003117205,0.00004924687,0.008387923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2713821,"threshold_uncertainty_score":0.489394,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2262586465","doi":"10.1182/asheducation-2015.1.571","title":"Uncommon histiocytic disorders: Rosai–Dorfman, juvenile xanthogranuloma, and Erdheim–Chester disease","year":2015,"lang":"en","type":"article","venue":"Hematology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Erdheim–Chester disease; Medicine; Juvenile xanthogranuloma; Histiocytosis; Juvenile myelomonocytic leukemia; Rosai–Dorfman disease; Histiocyte; Langerhans cell histiocytosis; Vemurafenib; Pathology; Anakinra; Sinus Histiocytosis with Massive Lymphadenopathy; Cladribine; Immunology; Disease; Internal medicine; Cancer; Haematopoiesis; Biology","authors":[{"name":"Julien Haroche","is_ca":false},{"name":"Oussama Abla","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02601474508566295,"gpt":0.2796982929659326,"spread":0.2536835478802697,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009018239,0.0002232726,0.0004941591,0.0001099739,0.00008139085,0.00001654393,0.00006634816,0.000108613,0.00009580048],"category_scores_gemma":[0.000136251,0.0001883645,0.00008196233,0.0001267561,0.0002362972,0.0000734542,0.00006085979,0.0001204737,0.0002265019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008541528,"about_ca_system_score_gemma":0.0001935695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001052119,"about_ca_topic_score_gemma":0.0001464841,"domain_scores_codex":[0.9987773,0.00005176845,0.0002778754,0.0003717253,0.0001841925,0.0003371059],"domain_scores_gemma":[0.9988706,0.0000611084,0.00007535409,0.0003814415,0.00005541479,0.0005561426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001156841,0.001981201,0.9214126,0.0006078834,0.0003011581,0.001717033,0.00132267,0.000008838711,0.00001598337,0.02179825,0.0329857,0.01669188],"study_design_scores_gemma":[0.05901692,0.003632208,0.2432111,0.0009788787,0.003714395,0.004093282,0.001956465,0.006182868,0.0002677291,0.08814245,0.5864856,0.002318173],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9692213,0.01078628,0.000442002,0.004688527,0.0004337043,0.0006802137,0.00002689123,0.0001962933,0.01352481],"genre_scores_gemma":[0.9968267,0.00008398203,0.0005853735,0.0004813307,0.00003876203,0.00007258304,0.00008848642,0.0000347937,0.001788003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6782015,"threshold_uncertainty_score":0.768128,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2023462735","doi":"10.2350/09-03-0622-oa.1","title":"Clinicopathologic Features of Histiocytic Lesions following ALL, with a Review of the Literature","year":2009,"lang":"en","type":"review","venue":"Pediatric and Developmental Pathology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Histiocyte; Pathology; Medicine; Histiocytosis; Disease","authors":[{"name":"Eumenia Castro","is_ca":false},{"name":"Cristina González","is_ca":false},{"name":"J. Barry Boyd","is_ca":false},{"name":"Hernán Correa","is_ca":false},{"name":"J-P. de Chadarevian","is_ca":false},{"name":"Raymond E. Felgar","is_ca":false},{"name":"Nicole Graf","is_ca":false},{"name":"Eric Lowe","is_ca":false},{"name":"John T. Manning","is_ca":false},{"name":"Maria Proytcheva","is_ca":false},{"name":"Christof Senger","is_ca":true},{"name":"Katayoon Shayan","is_ca":false},{"name":"Jaroslav Štěrba","is_ca":false},{"name":"A Werner","is_ca":false},{"name":"Urvashi Surti","is_ca":false},{"name":"Ronald Jaffe","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02908953275814409,"gpt":0.3261691961333056,"spread":0.2970796633751615,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002530306,0.0003835279,0.002098126,0.0001694688,0.00007066649,0.00000475916,0.0001521579,0.0003118636,0.00001626826],"category_scores_gemma":[0.0002553117,0.0001931171,0.0004530264,0.0005872264,0.0001242868,0.00002625889,0.00009806653,0.0003747985,0.000005416889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009046627,"about_ca_system_score_gemma":0.0008319751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002152126,"about_ca_topic_score_gemma":0.000001243638,"domain_scores_codex":[0.9981858,0.0001563499,0.0007843509,0.0004046993,0.0002444049,0.0002244119],"domain_scores_gemma":[0.9988379,0.0001525739,0.0005745513,0.0002835576,0.00006554458,0.00008584472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004194416,0.0004546918,0.002435977,0.1261091,0.0002780423,0.001294403,0.0003120888,1.612564e-8,3.369286e-7,0.0000689464,0.00261956,0.8663849],"study_design_scores_gemma":[0.00480648,0.002153817,0.02091482,0.3103639,0.0324934,0.01844585,0.0001282998,1.148209e-7,0.000001600964,0.0001968311,0.6093421,0.001152745],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009824842,0.9961038,0.000003218104,0.0000557861,0.0001279774,0.001037582,0.00005112099,0.00001451936,0.0016235],"genre_scores_gemma":[0.0005493763,0.9959346,0.002134628,0.0004175692,0.0000428414,0.00005344973,0.0001846683,0.00002382735,0.0006590164],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8652322,"threshold_uncertainty_score":0.7875087,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2971014165","doi":"10.1007/s12519-019-00304-9","title":"Childhood Langerhans cell histiocytosis: a disease with many faces","year":2019,"lang":"en","type":"review","venue":"World Journal of Pediatrics","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Hepatosplenomegaly; Dermatology; Histiocytosis; Pathology; Rash; Skin biopsy; Biopsy; Disease","authors":[{"name":"Alexander K. C. Leung","is_ca":true},{"name":"Joseph M. Lam","is_ca":true},{"name":"Kin Fon Leong","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02311642870118905,"gpt":0.2860552188515478,"spread":0.2629387901503588,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001544849,0.0004561626,0.001970035,0.0008480872,0.00005940153,0.0000399261,0.0002253995,0.000111672,0.0001884247],"category_scores_gemma":[0.00005430673,0.0002817507,0.0007207578,0.0006797562,0.00003794525,0.00007727482,0.00003454131,0.0006345203,0.0001869475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003383655,"about_ca_system_score_gemma":0.002031522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004469766,"about_ca_topic_score_gemma":0.000004791909,"domain_scores_codex":[0.9979137,0.00006101229,0.0007863625,0.0002653057,0.0006702944,0.000303326],"domain_scores_gemma":[0.9976103,0.0001240527,0.001238886,0.0003614764,0.000179803,0.0004854351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003247544,0.00359251,0.004500896,0.07264184,0.001127719,0.005361954,0.0002552442,0.00001167783,3.508261e-8,0.00006935888,0.06283563,0.8492784],"study_design_scores_gemma":[0.001984662,0.0004360937,0.0002188071,0.005687693,0.02207587,0.0002324535,0.00002148897,6.291345e-7,5.514308e-8,0.000009057737,0.969056,0.0002772041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000721927,0.9942157,0.00004577549,0.00008889593,0.0004225589,0.0006195556,0.0001017164,0.0000171733,0.004416396],"genre_scores_gemma":[0.0003192016,0.985079,0.0005958598,0.00006597795,0.0009200656,0.00001312722,0.000069416,0.0000869022,0.01285047],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9062204,"threshold_uncertainty_score":0.9999635,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2077344703","doi":"10.1046/j.1365-2141.2002.03232.x","title":"THE LANGERHANS CELL HISTIOCYTOSIS X FILES REVEALED","year":2002,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary; Alberta Children's Hospital","funders":"Louisiana State University; Yale University","keywords":"Langerhans cell histiocytosis; Histiocytosis X; Histiocytosis; Medicine; Dermatology; Pathology","authors":[{"name":"Arty R. Coppes‐Zantinga","is_ca":true},{"name":"R. Maarten Egeler","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01381003149728896,"gpt":0.2260560722221078,"spread":0.2122460407248188,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276317,0.00007823573,0.0003636157,0.00004817446,0.0001653752,0.00002496774,0.0001028832,0.00006612509,0.0006207724],"category_scores_gemma":[0.000177641,0.00006059218,0.0001409906,0.00007596292,0.0001170602,0.00003800227,0.00001358668,0.0001810999,0.00009647285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005162409,"about_ca_system_score_gemma":0.00003977578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004204388,"about_ca_topic_score_gemma":0.00004927592,"domain_scores_codex":[0.9991254,0.00005899167,0.0003687375,0.00008499307,0.000167474,0.0001944481],"domain_scores_gemma":[0.9993024,0.0001290617,0.0002161057,0.0001135319,0.0001337254,0.0001052147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"case_report","study_design_scores_codex":[0.0001760693,0.001293685,0.007698704,0.0001615751,0.0004468669,0.1303351,0.0005132101,0.000002937675,0.000162248,0.0003959886,0.7152441,0.1435695],"study_design_scores_gemma":[0.007590182,0.0009204962,0.005405299,0.0005953386,0.0006252513,0.6313886,0.0006102929,0.0001357862,0.0005097103,0.0007663834,0.3512305,0.0002221149],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93048,0.03967629,0.00008921496,0.003533838,0.0004005562,0.0001537592,0.00001263028,0.00001710569,0.02563661],"genre_scores_gemma":[0.9874977,0.004829655,0.0006011912,0.000322197,0.00007780879,0.000004756138,0.000002761044,0.00001439062,0.006649579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5010535,"threshold_uncertainty_score":0.6797023,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012056039","doi":"10.1016/j.ijporl.2008.02.001","title":"Langerhans’ cell histiocytosis of the temporal bone in children","year":2008,"lang":"en","type":"article","venue":"International Journal of Pediatric Otorhinolaryngology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Temporal bone; Histiocytosis; Pathology; Dermatology; Anatomy; Disease","authors":[{"name":"Issam Saliba","is_ca":true},{"name":"K. Sidani","is_ca":true},{"name":"Fouad El Fata","is_ca":false},{"name":"P Arcand","is_ca":true},{"name":"Marie‐Claude Quintal","is_ca":true},{"name":"Anthony Abela","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01042144507692738,"gpt":0.2399087452746726,"spread":0.2294873001977452,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001081414,0.00009587574,0.0002823625,0.0003370183,0.0000242259,0.000002680345,0.0002441834,0.00008197953,0.0001021623],"category_scores_gemma":[0.0001021708,0.00006605061,0.0001825948,0.0001666302,0.00007400068,0.00006686422,0.00004648979,0.0002207474,0.00001047287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00014794,"about_ca_system_score_gemma":0.0003078201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002300229,"about_ca_topic_score_gemma":0.00001140866,"domain_scores_codex":[0.9988117,0.00004945317,0.0005194929,0.00009662494,0.0004040278,0.0001186899],"domain_scores_gemma":[0.9990892,0.00004758265,0.0004523102,0.0001176624,0.0002369286,0.0000563009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001440114,0.0005676709,0.9963555,0.000006684856,0.0001003339,0.0003140329,0.0001769811,0.000009778802,0.0002096493,0.00002674891,0.00189392,0.0001946956],"study_design_scores_gemma":[0.003561704,0.0002363083,0.9925742,0.00001280323,0.0001226507,0.002360725,0.00001279846,0.000009788199,0.000374229,0.00006773752,0.0006123952,0.00005465543],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964097,0.001386451,0.0000273122,0.0004941748,0.0005881606,0.0001240264,0.00001505734,0.000004105803,0.0009510127],"genre_scores_gemma":[0.9980351,0.0005100805,0.0003999041,0.0001527792,0.0004828375,0.000002205872,0.000007829884,0.000009883281,0.0003994119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003781287,"threshold_uncertainty_score":0.2693466,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2094780851","doi":"10.1097/pat.0000000000000256","title":"Langerhans cell histiocytosis: a comprehensive review","year":2015,"lang":"en","type":"review","venue":"Pathology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"Langerin; Langerhans cell histiocytosis; Pathology; Immunohistochemistry; Disease; Biology; Somatic cell; Population; Histiocytosis; Immunology; Medicine; Immune system; Dendritic cell; Gene; Genetics","authors":[{"name":"Dina El Demellawy","is_ca":true},{"name":"James Lee Young","is_ca":true},{"name":"Joseph de Nanassy","is_ca":true},{"name":"Elizaveta Chernetsova","is_ca":true},{"name":"Ahmed Nasr","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1251912044109295,"gpt":0.4026368262713085,"spread":0.2774456218603791,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001282091,0.0004271131,0.003105009,0.0001357565,0.00003679415,0.000004675113,0.0001309048,0.000327218,0.0002955513],"category_scores_gemma":[0.00006221348,0.0003100782,0.0004916863,0.0002152403,0.00009439766,0.00001404091,0.00006572727,0.0003281584,0.00303783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002762646,"about_ca_system_score_gemma":0.0005954941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001021654,"about_ca_topic_score_gemma":0.000001356367,"domain_scores_codex":[0.9982899,0.000205714,0.0005228309,0.0004812118,0.0001914609,0.0003088556],"domain_scores_gemma":[0.9986778,0.00006115132,0.0002870207,0.0006068985,0.0001605211,0.0002066373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004702883,0.0002195449,0.000002144381,0.1031571,0.0001187287,0.002070592,0.00002902656,6.421246e-9,9.736981e-8,0.00001603311,0.0575751,0.836807],"study_design_scores_gemma":[0.0006200497,0.0002371109,0.00000113236,0.03043385,0.005769898,0.001741353,0.000007125981,1.954088e-7,7.780628e-8,0.00001629331,0.96096,0.0002129139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000001007487,0.9719265,0.000008536304,0.00009321341,0.0002917145,0.001379638,0.0001164642,0.0000745543,0.02610845],"genre_scores_gemma":[6.18858e-7,0.9919761,0.0003785265,0.001010238,0.0001079663,0.0003750157,0.001011888,0.00006716602,0.005072491],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9033849,"threshold_uncertainty_score":0.9999352,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2054256245","doi":"10.1002/pbc.20676","title":"Pulmonary Langerhans cell histiocytosis: A variable disease in childhood","year":2005,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Hospital for Sick Children; McMaster University Medical Centre","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Histiocytosis; Pediatrics; Context (archaeology); Medical record; Retrospective cohort study; Lung; High-resolution computed tomography; Radiological weapon; Pathological; Disease; Surgery; Internal medicine","authors":[{"name":"Isaac Odame","is_ca":true},{"name":"Patricia Li","is_ca":true},{"name":"Loretta M. S. Lau","is_ca":true},{"name":"Wendy Doda","is_ca":true},{"name":"Mary Noseworthy","is_ca":true},{"name":"Paul Babyn","is_ca":true},{"name":"Sheila Weitzman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005665682556804923,"gpt":0.2279476388907165,"spread":0.2222819563339116,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006165287,0.0001935731,0.0002717628,0.0001695053,0.00005755803,0.00001196942,0.00008263183,0.00007145815,0.0009359482],"category_scores_gemma":[0.00002381967,0.0001765039,0.00008159274,0.0004429997,0.00001842215,0.0000847304,0.0000282306,0.0001624732,0.0001321137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001641223,"about_ca_system_score_gemma":0.0005304824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007768784,"about_ca_topic_score_gemma":0.0000645272,"domain_scores_codex":[0.9987586,0.00001869088,0.0002506135,0.0003586048,0.0002479089,0.0003655721],"domain_scores_gemma":[0.999324,0.00002504887,0.00006839343,0.0002654222,0.00003341223,0.0002837874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001959209,0.006931351,0.9789298,0.0003865593,0.00009412685,0.0004862181,0.0003982814,0.0003403762,0.00004903487,0.00006065857,0.004305361,0.007822357],"study_design_scores_gemma":[0.02021371,0.0003759005,0.8939299,0.0002871301,0.007048927,0.00006564504,0.00009257752,0.001338321,0.0001874938,0.0003411701,0.07508318,0.001036072],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9166617,0.05074102,0.00002105079,0.001045434,0.0002169989,0.0006253558,0.0001507399,0.0001156235,0.03042206],"genre_scores_gemma":[0.9893097,0.0035694,0.0006312549,0.0006340083,0.001023929,0.0002829375,0.00006031542,0.00003676574,0.004451687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08499988,"threshold_uncertainty_score":0.9999774,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2328668136","doi":"10.1097/bor.0b013e32834db53e","title":"Langerhans cell histiocytosis and Erdheim–Chester disease","year":2011,"lang":"en","type":"review","venue":"Current Opinion in Rheumatology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; SickKids Foundation","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Histiocytosis; Histiocyte; Immune dysregulation; Erdheim–Chester disease; Disease; Pathogenesis; Immunology; Pathology","authors":[{"name":"Marta Wilejto","is_ca":true},{"name":"Oussama Abla","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1347452296144722,"gpt":0.3895773932899747,"spread":0.2548321636755025,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007486164,0.0004248694,0.001651223,0.0003400562,0.00004266089,0.00001098335,0.0001102689,0.0002505644,0.0001994192],"category_scores_gemma":[0.00005513769,0.000339266,0.0002394541,0.0001599162,0.0001414274,0.00003576944,0.00008838642,0.0003460867,0.0002968342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001427311,"about_ca_system_score_gemma":0.0003677246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003857876,"about_ca_topic_score_gemma":0.000001293147,"domain_scores_codex":[0.9982703,0.0001149737,0.0006223174,0.0005564477,0.0001049562,0.0003310457],"domain_scores_gemma":[0.9989502,0.00009846798,0.0002419036,0.0003961817,0.00002894437,0.0002843199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004669576,0.0008453511,0.008265877,0.1579047,0.0001094089,0.00002059148,0.0001876846,1.723198e-8,3.091043e-9,0.0009408785,0.006922597,0.8247561],"study_design_scores_gemma":[0.001145812,0.00006493515,0.0002602737,0.03069435,0.0004703112,0.0001185758,0.000009314104,0.000004518352,1.944192e-8,0.00007983492,0.9668914,0.0002606266],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006892878,0.9957885,0.00002082296,0.00003527823,0.002746188,0.0008022652,0.00007807615,0.00004280034,0.0004172096],"genre_scores_gemma":[0.0001379909,0.998469,0.00005077454,0.000003852766,0.00002396591,0.0003061838,0.0007274654,0.00005149455,0.0002292905],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9599688,"threshold_uncertainty_score":0.9999059,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1992672718","doi":"10.1111/bjh.13347","title":"Haematopoietic stem cell transplantation for refractory Langerhans cell histiocytosis: outcome by intensity of conditioning","year":2015,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; BC Children's Hospital","funders":"National Cancer Institute","keywords":"Medicine; Transplantation; Internal medicine; Chemotherapy; Langerhans cell histiocytosis; Refractory (planetary science); Total body irradiation; Hematopoietic stem cell transplantation; Surgery; Cytarabine; Oncology; Alemtuzumab; Stem cell; Gastroenterology; Cyclophosphamide; Disease; Biology","authors":[{"name":"Paul Veys","is_ca":false},{"name":"Vasanta Nanduri","is_ca":false},{"name":"K. Scott Baker","is_ca":false},{"name":"Wensheng He","is_ca":false},{"name":"Giuseppe Bandini","is_ca":false},{"name":"Andrea Biondi","is_ca":false},{"name":"Arnaud Dalissier","is_ca":false},{"name":"Jeffrey Davis","is_ca":true},{"name":"Gretchen Eames","is_ca":false},{"name":"R. Maarten Egeler","is_ca":true},{"name":"Alexandra H. Filipovich","is_ca":false},{"name":"Alain Fischer","is_ca":false},{"name":"H. Jürgens","is_ca":false},{"name":"Robert A. Krance","is_ca":false},{"name":"Edoardo Lanino","is_ca":false},{"name":"Wing Leung","is_ca":false},{"name":"Susanne Matthes","is_ca":false},{"name":"Gérard Michel","is_ca":false},{"name":"Paul J. Orchard","is_ca":false},{"name":"Anna Pieczonka","is_ca":false},{"name":"Olle Ringdén","is_ca":false},{"name":"Paul G. Schlegel","is_ca":false},{"name":"Anne Sîrvent","is_ca":false},{"name":"Kim Vettenranta","is_ca":false},{"name":"Mary Eapen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02907452498472599,"gpt":0.2787062183879791,"spread":0.2496316934032531,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002452402,0.0001110237,0.0007447056,0.0001005705,0.00004899364,0.00001055215,0.00007507236,0.0001171409,0.00002778096],"category_scores_gemma":[0.00005063731,0.0001158724,0.0001603736,0.00005898746,0.00009464702,0.0000918014,0.000006806707,0.0001577583,0.000007270659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009533328,"about_ca_system_score_gemma":0.0001590918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007657767,"about_ca_topic_score_gemma":0.00001924352,"domain_scores_codex":[0.9987486,0.0000529898,0.0006925136,0.0001253852,0.0002072056,0.0001733156],"domain_scores_gemma":[0.9986323,0.00009040096,0.0005340202,0.0000886023,0.0004905481,0.0001641229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"case_report","study_design_scores_codex":[0.01203768,0.01635431,0.1844352,0.01952836,0.00248774,0.1429803,0.01830919,0.0001456303,0.02693096,0.0008346009,0.543829,0.03212699],"study_design_scores_gemma":[0.0973713,0.01280961,0.01165388,0.005288055,0.008583993,0.6735045,0.01844736,0.0003910525,0.1403204,0.002694178,0.02745594,0.001479763],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890006,0.004521384,0.004693892,0.0002385267,0.0003136673,0.0002399621,0.0001127301,0.00001232849,0.0008668685],"genre_scores_gemma":[0.9976828,0.0001813364,0.001334502,0.0001517443,0.0000258027,0.000008669154,0.00007429033,0.00001952406,0.0005212971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5305241,"threshold_uncertainty_score":0.4725139,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1984562089","doi":"10.1038/eye.2000.151","title":"Erdheim-Chester disease: Two cases of orbital involvement","year":2000,"lang":"en","type":"article","venue":"Eye","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Erdheim–Chester disease; Medicine; Diabetes insipidus; Exophthalmos; Diplopia; Exophthalmus; Histiocyte; Pathology; Retroperitoneal fibrosis; Histiocytosis; Orbital Diseases; Dermatology; Eye disease; Fibrosis; Surgery; Disease; Internal medicine","authors":[{"name":"Tom Sheidow","is_ca":true},{"name":"David A. Nicolle","is_ca":true},{"name":"J.G. Heathcote","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01959813110942236,"gpt":0.2940498289264014,"spread":0.274451697816979,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002244568,0.00007439524,0.0001332574,0.00002394548,0.0000250702,0.000003888614,0.00002606446,0.0000135446,0.003059888],"category_scores_gemma":[0.00001309789,0.00005798155,0.00005950772,0.00005281221,0.00004601198,0.00002843284,0.000007840235,0.00002789606,0.0002620476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003078246,"about_ca_system_score_gemma":0.0000531253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001410214,"about_ca_topic_score_gemma":0.00001590277,"domain_scores_codex":[0.999501,0.000007752994,0.0001268997,0.0001149847,0.0001415123,0.0001078566],"domain_scores_gemma":[0.9996575,0.00001337945,0.00002051884,0.0001779076,0.00001905537,0.0001117149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001648533,0.005224221,0.8033577,0.0003869747,0.0007200292,0.004595355,0.001544703,0.00004433969,0.0003061756,0.0009432675,0.01611792,0.1651108],"study_design_scores_gemma":[0.01661306,0.001560852,0.7864019,0.0005821692,0.001225406,0.00007068666,0.0003740191,0.0003022259,0.001581194,0.0008637615,0.1899337,0.0004910262],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818587,0.0007756589,0.000003613044,0.0002739645,0.00003944958,0.0001596549,0.00002336048,0.00001921357,0.01684641],"genre_scores_gemma":[0.9844581,0.00002449084,0.000138964,0.0001928112,0.00003851955,0.00001321143,0.0000497401,0.00000959778,0.01507456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1738157,"threshold_uncertainty_score":0.9978514,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W590952344","doi":"10.1017/cbo9780511545252","title":"Histiocytic Disorders of Children and Adults","year":2005,"lang":"en","type":"book","venue":"Cambridge University Press eBooks","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Histiocyte; Histiocytosis; Langerhans cell histiocytosis; Medicine; Juvenile xanthogranuloma; Hemophagocytic lymphohistiocytosis; Presentation (obstetrics); Pathology; Disease","authors":[{"name":"Sheila Weitzman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005801633122045674,"gpt":0.1860945124693242,"spread":0.1802928793472786,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00003023469,0.0003056227,0.0005565486,0.0001815037,0.00007728479,0.000006616665,0.000130686,0.0002685796,0.000005792525],"category_scores_gemma":[0.00001064733,0.0003306174,0.0001724202,0.00001283441,0.0003508341,0.00003497645,0.0001181018,0.0002381474,0.000006049136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000353568,"about_ca_system_score_gemma":0.0003592782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003998182,"about_ca_topic_score_gemma":0.000009579771,"domain_scores_codex":[0.9989341,0.00002022143,0.0001872943,0.0004228581,0.0002256857,0.0002098453],"domain_scores_gemma":[0.9991283,0.00003125027,0.0001879522,0.000384002,0.00008087017,0.0001875801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003594262,0.001001958,0.001883128,0.002625798,0.004572453,0.000662474,0.0006651536,0.000006525218,0.00001331179,0.2990075,0.4895021,0.1964653],"study_design_scores_gemma":[0.01376691,0.0006340523,0.008174106,0.001615691,0.003350107,0.00009897875,0.00004413774,0.0001009127,0.00005246249,0.000008089164,0.9714349,0.0007196787],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.01014854,0.001081659,0.00003421193,0.00001576124,0.00005775349,0.0007445237,0.0003950114,0.00005988897,0.9874626],"genre_scores_gemma":[0.01571401,0.0006824855,0.0001318146,0.0000306572,0.00006254046,8.670187e-7,0.000341995,0.00003981676,0.9829958],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.4819328,"threshold_uncertainty_score":0.9999146,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2070136930","doi":"10.2310/7070.2003.35266","title":"Langerhans' Cell Histiocytosis in the Paediatric Population: Presentation and Treatment of Head and Neck Manifestationsy","year":2003,"lang":"en","type":"article","venue":"The Journal of Otolaryngology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"Health Sciences Centre; Dalhousie University","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Cervical lymphadenopathy; Etiology; Eosinophilic granuloma; Dermatology; Otitis; Histiocytosis; Presentation (obstetrics); Rash; Otorhinolaryngology; Population; Surgery; Disease; Pathology","authors":[{"name":"Lesley‐Ann Cochrane","is_ca":true},{"name":"Mark E. Prince","is_ca":false},{"name":"Kevin Clarke","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01874406360235126,"gpt":0.2786194904848757,"spread":0.2598754268825245,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001757478,0.0000622837,0.0001725578,0.00009271778,0.00004377781,0.00000377149,0.00002663209,0.00003164079,0.00001807266],"category_scores_gemma":[0.0000357301,0.00003249133,0.00002714604,0.0001017284,0.00004388916,0.00003928726,0.000003000834,0.00005071039,0.000001003402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003845482,"about_ca_system_score_gemma":0.00003391491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002175689,"about_ca_topic_score_gemma":0.00008626849,"domain_scores_codex":[0.9993924,0.0001697971,0.0002269274,0.00004727147,0.0000936273,0.00006997061],"domain_scores_gemma":[0.9995263,0.0001739985,0.0001572867,0.00007912787,0.00003644521,0.00002689839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002518229,0.0005568729,0.9913493,0.0000384077,0.00005976564,0.00008613793,0.00390207,0.00001924105,0.0001587588,0.0004300124,0.00009611077,0.003051499],"study_design_scores_gemma":[0.003542217,0.001427397,0.9918604,0.00001442558,0.0003120324,0.0009980585,0.0006184448,0.0000369056,0.0001136643,0.0004471232,0.0005988006,0.00003056942],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949121,0.003318815,0.00003683758,0.0006127688,0.00003744661,0.0002198829,0.00000172238,0.000001258469,0.0008591997],"genre_scores_gemma":[0.9980295,0.001397167,0.000381293,0.00006500467,0.00002186955,0.000004294958,0.000004400696,0.000004208135,0.00009220341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003290394,"threshold_uncertainty_score":0.1324958,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2051700063","doi":"10.1016/s0959-8049(00)00296-3","title":"Abundant expression of CD40 and CD40-ligand (CD154) in paediatric Langerhans cell histiocytosis lesions","year":2000,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary; Alberta Children's Hospital","funders":"Histiocytosis Association","keywords":"CD154; CD40; Langerhans cell histiocytosis; Antigen-presenting cell; Cell adhesion molecule; Biology; T cell; Pathology; Immunology; Medicine; Immune system; Cytotoxic T cell; In vitro","authors":[{"name":"R. Maarten Egeler","is_ca":true},{"name":"Blaise E. Favara","is_ca":false},{"name":"Jon D. Laman","is_ca":false},{"name":"Eric Claassen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01182003127344445,"gpt":0.2533380794896822,"spread":0.2415180482162377,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001996155,0.0001003052,0.000263407,0.0001405769,0.0000339561,0.000007316321,0.00005893795,0.00001925144,0.0004965113],"category_scores_gemma":[0.0000197485,0.00007265136,0.00006913126,0.0001327782,0.00004569298,0.00005528758,0.0000130804,0.0001388232,0.00001514515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006564193,"about_ca_system_score_gemma":0.00009076284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004361033,"about_ca_topic_score_gemma":0.0000165773,"domain_scores_codex":[0.999112,0.0000827464,0.0003692175,0.0001030896,0.0002081329,0.0001248008],"domain_scores_gemma":[0.9995002,0.00002759675,0.0001788301,0.0001002599,0.00006565494,0.0001274608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002582322,0.002294607,0.2206466,0.0005221516,0.0001943923,0.004555854,0.006751351,0.0005373496,0.05843373,0.00001289181,0.02547747,0.6779913],"study_design_scores_gemma":[0.02787548,0.002677471,0.6666089,0.002294686,0.0009909177,0.0003787504,0.0007032991,0.0000998812,0.03514047,0.00005007717,0.2626893,0.0004908337],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739147,0.009286235,0.00002171922,0.0002365483,0.00009630491,0.00009617624,0.0000123179,0.000004245048,0.01633169],"genre_scores_gemma":[0.9919016,0.004483923,0.0003663106,0.00008686488,0.0001244358,0.000001277939,0.000001688993,0.00002043697,0.003013416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6775005,"threshold_uncertainty_score":0.543645,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2620137631","doi":"10.1302/0301-620x.84b6.12585","title":"Eosinophilic granuloma","year":2002,"lang":"en","type":"article","venue":"Journal of Bone and Joint Surgery - British Volume","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; SickKids Foundation; Mount Sinai Hospital","funders":"","keywords":"Eosinophilic granuloma; Granuloma; Medicine; Dermatology; Pathology","authors":[{"name":"Frank Plasschaert","is_ca":true},{"name":"C. Samuel Craig","is_ca":true},{"name":"Randall Bell","is_ca":true},{"name":"W. G. Cole","is_ca":true},{"name":"J.S. Wunder","is_ca":true},{"name":"Benjamin A. Alman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02457723948855662,"gpt":0.2048617623983612,"spread":0.1802845229098046,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002725198,0.0001074046,0.0007110107,0.0002008571,0.0000863509,0.00005436559,0.00001294612,0.00006471884,0.001047344],"category_scores_gemma":[0.0001551157,0.0001092732,0.000319842,0.0001273515,0.00008188825,0.0001621675,0.00001259534,0.0001621067,0.00005100528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003918234,"about_ca_system_score_gemma":0.00004131975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001211322,"about_ca_topic_score_gemma":0.00001200141,"domain_scores_codex":[0.998675,0.00002554624,0.000681216,0.0001231594,0.0002850338,0.0002099762],"domain_scores_gemma":[0.9991965,0.00004158523,0.0002797118,0.0001005206,0.0001330219,0.000248701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0001027244,0.001354027,0.1811252,0.0001944616,0.0003319499,0.01829389,0.0002236998,9.50103e-7,0.0002005363,0.00001403391,0.4532853,0.3448732],"study_design_scores_gemma":[0.004116131,0.0007653667,0.7790295,0.00165079,0.0004719649,0.06134192,0.0001028494,0.0003663029,0.00004341339,0.0004596444,0.15132,0.0003320168],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758195,0.01881857,0.00002791296,0.001731367,0.0002819671,0.00007578057,0.000007523911,0.0000140282,0.003223312],"genre_scores_gemma":[0.987952,0.005139121,0.0002713904,0.0004544344,0.0001568489,0.000001560383,0.000003793704,0.00001816423,0.006002708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5979043,"threshold_uncertainty_score":0.9998658,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2563952912","doi":"10.1016/j.clim.2016.12.006","title":"The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus","year":2017,"lang":"en","type":"letter","venue":"Clinical Immunology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital; Native Mental Health Association of Canada; University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Allergy, Asthma and Immunology Foundation","keywords":"Autoimmunity; Medicine; Immunology; Disease; Autoimmune disease; Etiology; Germline mutation; Immune system; Mutation; Genetics; Biology; Pathology","authors":[{"name":"Robert J. Ragotte","is_ca":true},{"name":"Anita Dhanrajani","is_ca":true},{"name":"Julian Pleydell-Pearce","is_ca":true},{"name":"Kate L. Del Bel","is_ca":true},{"name":"Maja Tarailo‐Graovac","is_ca":true},{"name":"Clara van Karnebeek","is_ca":true},{"name":"Jefferson Terry","is_ca":true},{"name":"Christof Senger","is_ca":true},{"name":"Margaret L. McKinnon","is_ca":true},{"name":"Michael Seear","is_ca":true},{"name":"Julie Prendiville","is_ca":true},{"name":"Lori B. Tucker","is_ca":true},{"name":"Kristin Houghton","is_ca":true},{"name":"David A. Cabral","is_ca":true},{"name":"Jaime Guzmán","is_ca":true},{"name":"Ross E. Petty","is_ca":true},{"name":"Kelly L. Brown","is_ca":true},{"name":"Jenny Tekano","is_ca":true},{"name":"John K. Wu","is_ca":true},{"name":"Kimberly Morishita","is_ca":true},{"name":"Stuart E. Turvey","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04585637707085322,"gpt":0.3350315253953539,"spread":0.2891751483245007,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005854599,0.0002925197,0.001570098,0.0002159481,0.000156079,0.00001908695,0.0001932401,0.0007688107,0.000009765381],"category_scores_gemma":[0.001562311,0.0002206864,0.0002114429,0.0001107371,0.000932916,0.00005300622,0.0001467698,0.001109855,0.000007505572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001008916,"about_ca_system_score_gemma":0.0004321141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002001609,"about_ca_topic_score_gemma":0.00008568861,"domain_scores_codex":[0.9970193,0.0003116851,0.00177463,0.0003671797,0.0001809051,0.0003463041],"domain_scores_gemma":[0.9952732,0.001932741,0.001634574,0.001001514,0.0001237758,0.00003424659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002673007,0.0004531779,0.9751557,0.003710762,0.002584319,0.01278524,0.0007386376,0.000004057239,0.00009468537,0.00006612681,0.002583545,0.001556478],"study_design_scores_gemma":[0.03636488,0.005892993,0.760041,0.01222265,0.01217476,0.1563079,0.002242629,0.0007389332,0.00009763975,0.008222264,0.003848504,0.001845798],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9689557,0.02310587,0.000006197777,0.00637487,0.0007598309,0.0006926378,0.00001769025,0.00002218986,0.00006502008],"genre_scores_gemma":[0.994166,0.003721065,0.00009092285,0.001407804,0.00008813132,0.00005258194,0.00006443926,0.00004809725,0.000360953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2151147,"threshold_uncertainty_score":0.8999332,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2995014832","doi":"10.1038/s41590-019-0558-z","title":"The coming of age of Langerhans cell histiocytosis","year":2019,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Cancer Research UK","keywords":"Langerhans cell histiocytosis; Histiocytosis; Disease; Medicine; Langerhans cell; Immunology; Pathology; Dermatology; Antigen","authors":[{"name":"Carl E. Allen","is_ca":false},{"name":"Peter C. L. Beverley","is_ca":false},{"name":"Matthew Collin","is_ca":false},{"name":"Eli L. Diamond","is_ca":false},{"name":"R. Maarten Egeler","is_ca":true},{"name":"Florent Ginhoux","is_ca":false},{"name":"Christopher K. Glass","is_ca":false},{"name":"Milen Minkov","is_ca":false},{"name":"Barrett J. Rollins","is_ca":false},{"name":"Astrid G. S. van Halteren","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003881155020941465,"gpt":0.2380519551710227,"spread":0.2341708001500812,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005972582,0.00006649793,0.0002293015,0.00004414392,0.00002705443,0.000001332471,0.00008604945,0.0001895702,0.00008301543],"category_scores_gemma":[0.00004540286,0.00004220402,0.00006898685,0.00008217192,0.0001081313,0.000009760739,0.00002439679,0.0002295092,0.0000326567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003577954,"about_ca_system_score_gemma":0.00004666798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006071447,"about_ca_topic_score_gemma":0.00001329409,"domain_scores_codex":[0.9995366,0.00002184074,0.0001515124,0.000089993,0.0000858468,0.0001141955],"domain_scores_gemma":[0.9994418,0.0001191429,0.00009407938,0.0002722839,0.00006025434,0.00001244904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002327986,0.001685392,0.1173277,0.0005756494,0.001781123,0.0001375113,0.002308383,0.000005570651,0.7986217,0.02146193,0.005409452,0.04835768],"study_design_scores_gemma":[0.01671231,0.003173367,0.2302424,0.0003575435,0.000756117,0.00009867128,0.001760264,0.00006370934,0.2448173,0.001351098,0.5003085,0.0003587893],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9490398,0.01141175,0.000008704184,0.0003335158,0.0003459814,0.0001958405,0.000008743038,0.00001058878,0.03864511],"genre_scores_gemma":[0.9942984,0.0002040366,0.0001666813,0.00007023871,0.000009219232,0.000003833942,0.00002420938,0.000008093227,0.005215309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5538043,"threshold_uncertainty_score":0.172103,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2431678509","doi":"10.1002/pbc.26104","title":"Langerhans cell histiocytosis is a neoplasm and consequently its recurrence is a relapse: In memory of Bob Arceci","year":2016,"lang":"en","type":"review","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Neoplasm; Histiocytosis; Oncology; Pathology; Disease","authors":[{"name":"R. Maarten Egeler","is_ca":true},{"name":"Satyendra Katewa","is_ca":false},{"name":"Pieter J. M. Leenen","is_ca":false},{"name":"Peter C. L. Beverley","is_ca":false},{"name":"Matthew Collin","is_ca":false},{"name":"Florent Ginhoux","is_ca":false},{"name":"R.J. Arceci","is_ca":false},{"name":"Barrett J. Rollins","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03520222709381768,"gpt":0.3230786033169723,"spread":0.2878763762231547,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001413577,0.0005043711,0.001893639,0.0004450179,0.0000429077,0.00001116569,0.0001568419,0.0003671311,0.0007326505],"category_scores_gemma":[0.00007736579,0.0003752818,0.0003076966,0.0005779602,0.0000965061,0.00005250991,0.00007352777,0.0003511764,0.0001094532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002407004,"about_ca_system_score_gemma":0.001642905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006325279,"about_ca_topic_score_gemma":0.00007148429,"domain_scores_codex":[0.9976457,0.00007624197,0.0007915786,0.0007022863,0.0003712469,0.000412966],"domain_scores_gemma":[0.9984441,0.0002143205,0.0005719408,0.0004315267,0.000116003,0.0002220723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008380045,0.001042878,0.005214588,0.07868263,0.0006794194,0.0003900435,0.001200706,5.1771e-8,0.000003106061,0.00001174236,0.03451772,0.8781733],"study_design_scores_gemma":[0.004933584,0.0002910985,0.0001044503,0.01490743,0.0111012,0.0001059398,0.00002177631,0.000001470806,0.00004192429,0.00002227659,0.9679059,0.0005629651],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002288826,0.9910384,0.00000155182,0.0001879099,0.0003047019,0.001082103,0.00121558,0.00002484902,0.003856045],"genre_scores_gemma":[0.0007560806,0.991859,0.0001056373,0.000170256,0.0002859562,0.0004093848,0.00003934172,0.0000655726,0.006308827],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9333882,"threshold_uncertainty_score":0.9998699,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2908043940","doi":"10.1002/cam4.1844","title":"Langerhans cell histiocytosis in adults is associated with a high prevalence of hematologic and solid malignancies","year":2018,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute; National Institutes of Health; Lymphoma Foundation","keywords":"Medicine; Langerhans cell histiocytosis; Malignancy; Cohort; Hematologic malignancy; Etoposide; Histiocyte; Internal medicine; Histiocytosis; Pediatrics; Chemotherapy; Disease; Pathology","authors":[{"name":"Jennifer Ma","is_ca":false},{"name":"J. Laird","is_ca":false},{"name":"Karen Chau","is_ca":false},{"name":"Monica Chelius","is_ca":false},{"name":"Benjamin H. Lok","is_ca":true},{"name":"Joachim Yahalom","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01364256015879931,"gpt":0.2698038136967363,"spread":0.256161253537937,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008160112,0.0001355122,0.0004367141,0.00009059892,0.00002969774,0.000001317307,0.00004659166,0.00006465666,0.0005195446],"category_scores_gemma":[0.00008842742,0.00008739671,0.00001596516,0.0002300352,0.000443038,0.00002744588,0.00001410906,0.00006454941,0.000003841843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001213054,"about_ca_system_score_gemma":0.0001021189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027851,"about_ca_topic_score_gemma":0.0003933055,"domain_scores_codex":[0.9991298,0.00001708648,0.0002199529,0.0002367132,0.0002082285,0.0001881799],"domain_scores_gemma":[0.9994219,0.00004554158,0.0001297696,0.0001603432,0.0001591262,0.00008332613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0015003,0.0007570885,0.9648066,0.003375204,0.0002542574,0.0003113662,0.01371164,0.000001104494,0.003368712,0.0001376918,0.008223563,0.003552448],"study_design_scores_gemma":[0.03196399,0.008271842,0.9062846,0.02151963,0.001259559,0.00007855572,0.001548171,0.0002808112,0.02696377,0.0003118868,0.001088264,0.000428884],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917885,0.0046558,0.00001835455,0.001107507,0.00006919025,0.0002890996,0.0000414561,0.00002088996,0.002009197],"genre_scores_gemma":[0.9964933,0.001125841,0.00007562896,0.0005415655,0.00004900319,0.00005145057,0.00001261193,0.00001259724,0.001638041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.058522,"threshold_uncertainty_score":0.5688649,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2023658695","doi":"10.1097/00043426-200101000-00013","title":"Treatment of Langerhans Cell Histiocytosis With Pamidronate","year":2001,"lang":"en","type":"article","venue":"˜The œAmerican journal of pediatric hematology/oncology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Pathophysiology; Bone pain; Chemotherapy; Narcotic; Histiocytosis; Surgery; Dermatology; Internal medicine; Disease","authors":[{"name":"R. Peter Farran","is_ca":true},{"name":"Eldon Zaretski","is_ca":true},{"name":"R. Maarten Egeler","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01536932824164713,"gpt":0.2862169924532224,"spread":0.2708476642115752,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001721578,0.000240891,0.001274422,0.0002986348,0.0000777338,0.000004131322,0.0001616291,0.00009533809,0.0001123748],"category_scores_gemma":[0.00002033515,0.0001342692,0.0002349232,0.0005524185,0.000452083,0.00003750925,0.00001737016,0.0001902567,0.00003234558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004997274,"about_ca_system_score_gemma":0.0009590435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001601576,"about_ca_topic_score_gemma":0.00005866868,"domain_scores_codex":[0.9982867,0.0001805533,0.0006972124,0.0001973535,0.000276494,0.0003616619],"domain_scores_gemma":[0.9975433,0.0003745116,0.001320573,0.0002787723,0.000254761,0.000228066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008438307,0.01047251,0.7336729,0.0001284942,0.001790207,0.01424622,0.004027413,0.00006312763,0.0003087305,0.00018927,0.004192949,0.2224699],"study_design_scores_gemma":[0.05589912,0.218274,0.05812551,0.00009624366,0.01761956,0.1035105,0.01277252,0.0002960143,0.001264942,0.0005728386,0.5303975,0.001171262],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866359,0.002816026,0.0006867285,0.001709647,0.0001748174,0.0002703623,0.000008973874,0.00001619218,0.007681406],"genre_scores_gemma":[0.9934776,0.003230483,0.002147276,0.0002002368,0.000252592,0.00001888664,0.000005091137,0.0000280561,0.0006397435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6755474,"threshold_uncertainty_score":0.5475337,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2791616704","doi":"10.1212/cpj.0000000000000422","title":"Neuroradiologic manifestations of Erdheim-Chester disease","year":2018,"lang":"en","type":"article","venue":"Neurology Clinical Practice","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Erdheim–Chester disease; Diabetes insipidus; Histiocytosis; Spinal cord; Multiple sclerosis; Magnetic resonance imaging; Pathology; Internal medicine; Radiology; Disease","authors":[{"name":"Natalie Parks","is_ca":true},{"name":"Gaurav Goyal","is_ca":true},{"name":"Ronald S. Go","is_ca":true},{"name":"Jay Mandrekar","is_ca":true},{"name":"W. Oliver Tobin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07938285287384386,"gpt":0.4516046344625654,"spread":0.3722217815887215,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0003454324,0.0001075875,0.0002823192,0.00004470635,0.00006592138,0.000004506263,0.00008123031,0.0001191107,0.0002287721],"category_scores_gemma":[0.009316076,0.00008679293,0.0001182925,0.0001080124,0.0005968597,0.0001081062,0.00004246829,0.0003231982,0.0005012618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005080795,"about_ca_system_score_gemma":0.0001463674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001327511,"about_ca_topic_score_gemma":0.000003246536,"domain_scores_codex":[0.9984644,0.0003691512,0.000507086,0.0003427076,0.0001401109,0.0001765639],"domain_scores_gemma":[0.9966273,0.002270077,0.0002473693,0.0004163835,0.0002203869,0.000218431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01706405,0.008792457,0.9070147,0.00007945488,0.0005495479,0.01020256,0.0001622297,0.000006696313,0.00007028376,0.003198076,0.02100034,0.03185961],"study_design_scores_gemma":[0.002656284,0.005785907,0.8364052,0.000007612334,0.0008820196,0.0005870894,0.00001572048,0.0003413104,0.000003911052,0.0008641163,0.1523671,0.00008378576],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9370567,0.000109328,0.0002446335,0.02546575,0.0007421232,0.0003169349,0.00001034468,0.00005484434,0.03599932],"genre_scores_gemma":[0.9721097,0.0001081959,0.001607997,0.02545216,0.0002288409,0.00001023216,0.00001305109,0.00001531295,0.0004544779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1313668,"threshold_uncertainty_score":0.9990289,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1989090309","doi":"10.1002/pbc.21322","title":"Skeletal Langerhans cell histiocytosis in children: Permanent consequences and health‐related quality of life in long‐term survivors","year":2007,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Quality of life (healthcare); Histiocytosis; Pediatrics; Internal medicine; Disease","authors":[{"name":"Loretta M. S. Lau","is_ca":true},{"name":"Kyra E. Stuurman","is_ca":true},{"name":"Sheila Weitzman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.021449366279353,"gpt":0.3071749950434479,"spread":0.2857256287640949,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005145979,0.00016093,0.0005204819,0.0002570581,0.00003232403,0.000004634957,0.0000540429,0.00009818741,0.0001021374],"category_scores_gemma":[0.00003193389,0.000146325,0.00005794949,0.0004172274,0.0001241103,0.0000383552,0.00002043867,0.0001706895,0.000003918987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001423725,"about_ca_system_score_gemma":0.0004202827,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.05411419,"about_ca_topic_score_gemma":0.0182959,"domain_scores_codex":[0.9983909,0.00005907864,0.0006927633,0.0002884735,0.000245307,0.0003235406],"domain_scores_gemma":[0.9993333,0.00005773825,0.0002437206,0.0001430453,0.00003565146,0.0001864948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000685462,0.0007329984,0.9963202,0.0003888575,0.00005048309,0.0000340514,0.0007160184,0.000004245846,0.00002300572,0.00001765327,0.00004346304,0.001600506],"study_design_scores_gemma":[0.005011519,0.0001792227,0.9943178,0.00005078365,0.0001442672,0.00001124657,0.00007434014,0.000002498007,0.00006169237,0.0000159342,0.000007203806,0.0001234868],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9598694,0.0385889,0.000003269908,0.0004218964,0.00009085481,0.0004380254,0.00005360701,0.00001772031,0.0005163489],"genre_scores_gemma":[0.9933873,0.006128306,0.00004248735,0.0001596425,0.00007109682,0.00002328149,0.00004931033,0.00001443847,0.0001240805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03581829,"threshold_uncertainty_score":0.9996176,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4323532429","doi":"10.1182/bloodadvances.2022008414","title":"Dabrafenib, alone or in combination with trametinib, in <i>BRAF</i> V600–mutated pediatric Langerhans cell histiocytosis","year":2023,"lang":"en","type":"article","venue":"Blood Advances","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children; National Cancer Institute; National Institute for Health and Care Research; National Institutes of Health; Novartis Pharmaceuticals Corporation","keywords":"Trametinib; Dabrafenib; Medicine; Combination therapy; MEK inhibitor; Internal medicine; Adverse effect; Vomiting; Tolerability; Oncology; Langerhans cell histiocytosis; Gastroenterology; Vemurafenib; MAPK/ERK pathway; Cancer; Biology","authors":[{"name":"James A. Whitlock","is_ca":true},{"name":"Birgit Geoerger","is_ca":false},{"name":"Ira J. Dunkel","is_ca":false},{"name":"Sy Ha","is_ca":false},{"name":"Jeea Choi","is_ca":false},{"name":"Lisa Osterloh","is_ca":false},{"name":"Mark W. Russo","is_ca":false},{"name":"Darren Hargrave","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01175182767218733,"gpt":0.2581150176213485,"spread":0.2463631899491612,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001254343,0.000182372,0.0003607639,0.0004007765,0.00004307108,0.00001289262,0.00007137614,0.00006589581,0.00005991441],"category_scores_gemma":[0.0000753317,0.000135287,0.00003503489,0.001596239,0.00004204199,0.000143679,0.000014854,0.0001320207,0.00008309574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006815134,"about_ca_system_score_gemma":0.0001275655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001604131,"about_ca_topic_score_gemma":0.0009986461,"domain_scores_codex":[0.9987318,0.00004103499,0.0003042501,0.0003338067,0.0002737058,0.0003154399],"domain_scores_gemma":[0.9994778,0.0001385237,0.00009466148,0.000167521,0.00003880964,0.00008267349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001631631,0.009716426,0.959762,0.0008271897,0.00009220903,0.00394594,0.002127628,0.0005858418,0.0005906615,0.00006296737,0.001154472,0.01950304],"study_design_scores_gemma":[0.195338,0.01013077,0.73085,0.001114751,0.002015646,0.0002464899,0.005095002,0.001553824,0.01774043,0.001130212,0.03279385,0.00199111],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936886,0.001320721,0.00001802357,0.000459013,0.00007559094,0.0005450746,0.0000229974,0.0001390192,0.003730936],"genre_scores_gemma":[0.9949257,0.001267797,0.0008061336,0.0001254056,0.00003426736,0.0001285505,0.0001852294,0.00003177064,0.002495173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.228912,"threshold_uncertainty_score":0.5516843,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W175157959","doi":"","title":"Treatment and outcome of vertebral Langerhans cell histiocytosis at the Children's Hospital of Eastern Ontario.","year":2005,"lang":"en","type":"article","venue":"PubMed","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Eosinophilic granuloma; Histiocytosis; Pediatrics; Vertebral osteomyelitis; Surgery; Disease; Osteomyelitis; Pathology","authors":[{"name":"Chris W. Brown","is_ca":true},{"name":"James Jarvis","is_ca":false},{"name":"Mervyn Letts","is_ca":false},{"name":"Blair Carpenter","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01357934087104587,"gpt":0.208044417320802,"spread":0.1944650764497562,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003678557,0.0001149027,0.000255559,0.00003408951,0.00003490795,0.000003515818,0.00004039163,0.0000367027,0.00008524423],"category_scores_gemma":[0.000009087845,0.00006943048,0.00008915382,0.00003868532,0.00008520146,0.00002618535,0.00002665422,0.00003406509,0.00001168687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003273884,"about_ca_system_score_gemma":0.00002694985,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007555344,"about_ca_topic_score_gemma":0.006919959,"domain_scores_codex":[0.999343,0.00001010042,0.0002121484,0.0001419636,0.0001230212,0.0001697033],"domain_scores_gemma":[0.9995848,0.00001801006,0.00009318565,0.0002009669,0.00002028756,0.0000827401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006773877,0.0005993522,0.9463075,0.00001356724,0.0001469598,0.000003189082,0.0007805357,0.000001136884,0.000005742368,0.00001042875,0.0001764531,0.05188738],"study_design_scores_gemma":[0.003698636,0.00026973,0.9906131,0.000005106519,0.0003513704,0.00001008426,0.00003834723,0.000008663432,0.001183967,0.000003711691,0.003754716,0.00006257942],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910447,0.0005870867,0.000002415221,0.0006798342,0.0000498877,0.0006765825,0.00003705738,0.000009572454,0.006912851],"genre_scores_gemma":[0.9794417,0.00002780794,0.00006195418,0.00004885321,0.00002647427,0.0001708269,0.00003016151,0.00001024963,0.020182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0518248,"threshold_uncertainty_score":0.9990534,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1852564354","doi":"10.1177/229255030801600309","title":"Juvenile Xanthogranuloma: Case Report and Review of the Literature","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Plastic Surgery","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Juvenile xanthogranuloma; Medicine; Papule; Head and neck; Trunk; Surgery; Lesion; Resection; Juvenile; Girl; Dermatology; Pathology","authors":[{"name":"Tatiana Karine Simon Cypel","is_ca":true},{"name":"Ronald M. Zuker","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01649150108077188,"gpt":0.2308873375952946,"spread":0.2143958365145228,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002391472,0.00008233998,0.0003855237,0.0001477428,0.00009902524,0.00000508286,0.00002950484,0.00004018671,0.0001007994],"category_scores_gemma":[0.002459504,0.00005066921,0.0002052326,0.0002399207,0.0001372129,0.00003867918,0.000003523571,0.0001344475,0.000001102587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005096797,"about_ca_system_score_gemma":0.002190526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006465297,"about_ca_topic_score_gemma":0.0006855712,"domain_scores_codex":[0.9991834,0.00003277242,0.0004406863,0.00007065245,0.0001405045,0.0001319478],"domain_scores_gemma":[0.9986098,0.0003710468,0.0002820995,0.0001447885,0.0002131722,0.000379076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00002222329,0.00005156757,0.2377423,0.001196066,0.0001476089,0.6969336,0.0002644038,5.964815e-7,0.000003569698,0.00001014067,0.0623047,0.001323207],"study_design_scores_gemma":[0.0004193564,0.00006841651,0.08364468,0.01315505,0.0003317098,0.8836145,0.00004948126,0.000002076467,0.00001329052,0.00001178729,0.01862236,0.00006725275],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.924289,0.07388045,0.000006238384,0.0004016392,0.0008493303,0.00007805332,0.00003117273,0.000001445418,0.0004626485],"genre_scores_gemma":[0.9967448,0.002653173,0.00003625809,0.0002114498,0.00006400591,9.441774e-7,0.000005198616,0.000008069065,0.000276069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1866809,"threshold_uncertainty_score":0.3885899,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4295084519","doi":"10.1182/bloodadvances.2022007947","title":"Clinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Universiteit Leiden; Leids Universitair Medisch Centrum; Histiocytosis Association","keywords":"Langerhans cell histiocytosis; Histiocytosis; Cohort; Medicine; Cohort study; Internal medicine; Disease","authors":[{"name":"Paul G. Kemps","is_ca":false},{"name":"Timo C. E. Zondag","is_ca":false},{"name":"Helga B. Arnardóttir","is_ca":false},{"name":"Nienke Solleveld‐Westerink","is_ca":false},{"name":"Jelske Borst","is_ca":false},{"name":"Eline C. Steenwijk","is_ca":false},{"name":"Demi van Egmond","is_ca":false},{"name":"Joost F. Swennenhuis","is_ca":false},{"name":"Ellen Stelloo","is_ca":false},{"name":"Irene Trambusti","is_ca":false},{"name":"Robert M. Verdijk","is_ca":false},{"name":"Carel J.M. van Noesel","is_ca":false},{"name":"Arjen H.G. Cleven","is_ca":false},{"name":"Marijn A. Vermeulen","is_ca":false},{"name":"Marco J. Koudijs","is_ca":false},{"name":"Lenka Krsková","is_ca":false},{"name":"Cynthia Hawkins","is_ca":true},{"name":"R. Maarten Egeler","is_ca":false},{"name":"Jesper Brok","is_ca":false},{"name":"Tatiana von Bahr Greenwood","is_ca":false},{"name":"Karel Švojgr","is_ca":false},{"name":"Auke Beishuizen","is_ca":false},{"name":"Jan van Laar","is_ca":false},{"name":"Ulrike Pötschger","is_ca":false},{"name":"Caroline Hutter","is_ca":false},{"name":"Elena Sieni","is_ca":false},{"name":"Milen Minkov","is_ca":false},{"name":"Oussama Abla","is_ca":true},{"name":"Tom van Wezel","is_ca":false},{"name":"Cor van den Bos","is_ca":false},{"name":"Astrid G. S. van Halteren","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01135229235169421,"gpt":0.2951635525546391,"spread":0.2838112602029448,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001860243,0.00009923879,0.0002140315,0.0001173035,0.000143526,0.00001166324,0.0001246523,0.00001828306,0.0003387883],"category_scores_gemma":[0.00003808475,0.000100505,0.00005026353,0.0001467704,0.00001407954,0.0001168156,0.00004710507,0.0001404981,0.00002002621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001978024,"about_ca_system_score_gemma":0.0001022912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001453505,"about_ca_topic_score_gemma":0.0002960981,"domain_scores_codex":[0.9989628,0.00006355115,0.0002529108,0.00028299,0.0002936063,0.0001441448],"domain_scores_gemma":[0.9995919,0.00003310298,0.0001044017,0.0001862921,0.00002730993,0.0000570339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00002831943,0.01010101,0.9865434,0.000002717758,0.0001307123,0.00007189246,0.0008733699,0.0001286281,0.00002471248,0.00002255271,0.00003992581,0.002032822],"study_design_scores_gemma":[0.00515048,0.0008413932,0.9838642,0.000005134006,0.0002614817,0.00001014246,0.001979038,0.00003323436,0.00003142002,0.00007834456,0.007639608,0.0001055653],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861678,0.0007159183,0.000002807168,0.0001220429,0.0003000256,0.0006452844,0.0001328016,0.00004381027,0.01186947],"genre_scores_gemma":[0.9976421,0.0001091727,0.0002403908,0.0001655742,0.00007002139,0.0003068935,0.0003047207,0.00001588562,0.00114525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01147425,"threshold_uncertainty_score":0.4098473,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}