{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":985,"total_is_capped":false,"direct_labels_cover":1,"predictions_cover":985,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"1d6b1ea9b2ad","filters":{"topic":"Inflammasome and immune disorders"}},"results":[{"id":"W2748400555","doi":"10.1056/nejmoa1707914","title":"Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease","year":2017,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9109,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Canakinumab; Medicine; Placebo; Myocardial infarction; Hazard ratio; Internal medicine; Confidence interval; Randomized controlled trial; Clinical endpoint; C-reactive protein; Surgery; Gastroenterology; Inflammation; Disease; Pathology; Anakinra","retraction":null,"screen_n_in":null,"score":{"opus":0.01683589248186131,"gpt":0.2681017057267959,"spread":0.2512658132449346,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002986351,0.0001078003,0.000179074,0.00003328044,0.0001417775,0.00001760222,0.0002519776,0.0000361432,0.00002143985],"category_scores_gemma":[0.0001955795,0.00006454015,0.00006098013,0.00001171725,0.0001246612,0.000008519128,0.00001435838,0.00007266302,5.255757e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005730426,"about_ca_system_score_gemma":0.0002234674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003849007,"about_ca_topic_score_gemma":0.00006738611,"domain_scores_codex":[0.9994026,0.00002113371,0.0001976905,0.00009471545,0.000139824,0.000144022],"domain_scores_gemma":[0.9990832,0.00001273461,0.0003144704,0.0002955302,0.0001489591,0.000145152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01858122,0.0001452844,0.08391861,0.00008395752,0.0007846315,0.0001457396,0.0008856225,0.0001334965,0.366823,0.0003026088,0.0247571,0.5034388],"study_design_scores_gemma":[0.1145646,0.005776859,0.1209334,0.0003302728,0.0001457265,0.000147184,0.0001906524,0.00002723747,0.02590198,0.000488817,0.7311745,0.0003187736],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932047,0.002300543,0.0008967363,0.002740923,0.0003060211,0.0001376475,0.000002259016,0.000001858882,0.000409379],"genre_scores_gemma":[0.9956403,0.001068992,0.0001484896,0.0002866451,0.002196807,0.000002368472,0.000008594316,0.00001737806,0.0006303759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7064174,"threshold_uncertainty_score":0.2631871,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2788640168","doi":"10.1038/s41418-017-0012-4","title":"Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018","year":2018,"lang":"en","type":"review","venue":"Cell Death and Differentiation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6498,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Sunnybrook Hospital; University of Toronto","funders":"Institut Universitaire de France; National Institute on Drug Abuse; Weill Cornell Medical College; National Institute on Aging; Medical Research Council; Genentech; Institut National Du Cancer; National Heart, Lung, and Blood Institute; Francis Crick Institute; National Institute of General Medical Sciences; Ligue Contre le Cancer; National Cancer Institute; Labex Immuno-Oncology; Ministero dell’Istruzione, dell’Università e della Ricerca; Fondation pour la Recherche Médicale; Cancer Research UK; Wellcome Trust; National Institute of Allergy and Infectious Diseases; Fondation Leducq; Agence Nationale de la Recherche; E-Rare; European Commission; Associazione Italiana per la Ricerca sul Cancro; Association pour la Recherche sur le Cancer","keywords":"Programmed cell death; Necroptosis; Pyroptosis; Autophagy; Biology; Mitotic catastrophe; Cell biology; Apoptosis; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01656449216402441,"gpt":0.2511560553466172,"spread":0.2345915631825927,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001327655,0.0004136334,0.0006187864,0.0001096644,0.0001410816,0.00002559745,0.0003716498,0.0005317673,0.00003094253],"category_scores_gemma":[0.00001891089,0.0003048526,0.0004566207,0.0001165012,0.00004858045,0.000006605481,0.0001989159,0.0002297535,0.00001019326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002249131,"about_ca_system_score_gemma":0.0001113445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001239847,"about_ca_topic_score_gemma":0.00000372261,"domain_scores_codex":[0.9983591,0.0002026168,0.0005650915,0.0004357854,0.0001800439,0.0002573497],"domain_scores_gemma":[0.9983726,0.00002961601,0.0006972243,0.0007210933,0.0001183069,0.00006122525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00041468,0.006026296,0.0009654473,0.0586935,0.001871011,0.000007404608,0.001089983,0.00002902677,0.7647391,0.01434121,0.02070245,0.1311199],"study_design_scores_gemma":[0.001464408,0.0009883939,0.0003078824,0.0016973,0.001564831,0.000003959244,0.00007105358,0.00004100004,0.6067145,0.00161306,0.3846399,0.0008937267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04250961,0.9394127,0.004453722,0.00003659266,0.0008369035,0.001449674,0.0003335892,0.00001478353,0.01095238],"genre_scores_gemma":[0.08428498,0.9114102,0.0004879271,0.00008977698,0.00008367708,0.00005528779,0.002036088,0.000064951,0.001487102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3639375,"threshold_uncertainty_score":0.9999403,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2986700515","doi":"10.1056/nejmoa1912388","title":"Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction","year":2019,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2967,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Abbott Vascular; Esperion Therapeutics; Heart Research Institute; Bausch Health; Duke Clinical Research Institute; Eisai; Daiichi Sankyo Europe; Gilead Sciences; Servier; University of Glasgow; AstraZeneca; Amarin Corporation; Singulex; Ionis Pharmaceuticals; TG Therapeutics; Massachusetts Medical Society; Boston Scientific Corporation; Kowa Company; Sanofi; Institut de Cardiologie de Montréal; Celgene; Pfizer; Biogen; GlaxoSmithKline; Amgen; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Colchicine; Gout; Medicine; Pericarditis; Myocardial infarction; Inflammation; Pharmacology; Internal medicine; Cardiology","retraction":null,"screen_n_in":null,"score":{"opus":0.003206773287188557,"gpt":0.219258100176237,"spread":0.2160513268890485,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003545088,0.00008852856,0.000238476,0.000064935,0.00001357205,0.000002469007,0.00006233183,0.00006559057,0.00008802671],"category_scores_gemma":[0.0001163597,0.00006142801,0.00004694702,0.0000509317,0.00006614474,0.000005615405,0.00002454064,0.0001161102,0.000001822491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004558914,"about_ca_system_score_gemma":0.00006292222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000139676,"about_ca_topic_score_gemma":0.000005226529,"domain_scores_codex":[0.999302,0.00004528861,0.0003275851,0.00008264412,0.0001453052,0.00009715296],"domain_scores_gemma":[0.9994999,0.00002409262,0.0001767096,0.0001191646,0.0001112671,0.0000689336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01506946,0.00005792663,0.03716619,0.00007134086,0.0002919977,0.00001121314,0.0007080433,0.0001148318,0.8671423,0.00002828326,0.002245246,0.07709321],"study_design_scores_gemma":[0.1687282,0.009286051,0.4929043,0.0006336583,0.000236667,0.0005036209,0.0004030564,0.00002011283,0.03647372,0.0001323258,0.2903888,0.0002895489],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945936,0.003113579,0.00009456429,0.0008537219,0.0004224936,0.0000992233,0.000001239622,0.000001057644,0.0008204833],"genre_scores_gemma":[0.9965156,0.001728232,0.0000453772,0.0002744197,0.001149526,3.780256e-7,0.00001063466,0.000008186731,0.000267692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8306685,"threshold_uncertainty_score":0.2504962,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2118403357","doi":"10.4049/jimmunol.0901363","title":"Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2899,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institute on Aging","keywords":"Inflammasome; Cell biology; Receptor; Proinflammatory cytokine; Pattern recognition receptor; Transcription factor; Signal transduction; Priming (agriculture); Extracellular; Chemistry; Biology; Immunology; Innate immune system; Inflammation; Biochemistry; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.008729979862670994,"gpt":0.2226491614457145,"spread":0.2139191815830435,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000653105,0.0001919749,0.0002239483,0.00009354697,0.0002135413,0.00002925105,0.0002075644,0.000214506,0.00001988712],"category_scores_gemma":[0.0003725088,0.0001463767,0.00007648145,0.0001083277,0.00008845088,0.00005054306,0.00008696599,0.0003887976,0.000003411615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002813443,"about_ca_system_score_gemma":0.00003788343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001358914,"about_ca_topic_score_gemma":0.000001081743,"domain_scores_codex":[0.9985944,0.0002943063,0.0005413701,0.0001588728,0.0001326998,0.0002783363],"domain_scores_gemma":[0.9986562,0.00008183426,0.0007983412,0.0002188917,0.0002106898,0.00003411613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003619444,0.00002916156,0.0002002852,0.000005670322,0.00005103796,6.007944e-7,0.0005576576,0.0000166119,0.8119845,5.282765e-7,0.0005980216,0.186194],"study_design_scores_gemma":[0.001123972,0.0007822534,0.002114031,0.0001530467,0.00002557843,0.0001257522,0.001304749,0.00002319483,0.9897044,0.0001353378,0.004325624,0.000182009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962009,0.001352784,0.001189476,0.0007271786,0.0001854579,0.0001225163,0.000002568115,0.000009442788,0.000209657],"genre_scores_gemma":[0.9978198,0.001102084,0.0003128491,0.0003145716,0.0002735892,0.000002249712,0.00005975005,0.0000212308,0.00009386085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.186012,"threshold_uncertainty_score":0.5969068,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2140637559","doi":"10.1038/nm.3806","title":"A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases","year":2015,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2784,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trinity College","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Inflammasome; Pyrin domain; Experimental autoimmune encephalomyelitis; NALP3; Medicine; AIM2; Immunology; Nod; In vivo; NLRC4; Receptor; Inflammation; Caspase 1; Biology; Diabetes mellitus; Internal medicine; Endocrinology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01149896473672759,"gpt":0.2514125145929787,"spread":0.2399135498562511,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429521,0.0001504295,0.0002067826,0.00003224321,0.00005145502,0.000002506421,0.0002593297,0.000183633,0.000005393618],"category_scores_gemma":[0.0004040388,0.00007163083,0.0001590255,0.0001084517,0.0002933737,0.000002297737,0.00004668379,0.0000857006,5.300474e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001643329,"about_ca_system_score_gemma":0.0001551864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001536662,"about_ca_topic_score_gemma":0.00004169799,"domain_scores_codex":[0.9991958,0.0000426754,0.0002646648,0.0001585838,0.0001821623,0.0001561599],"domain_scores_gemma":[0.9989857,0.00005382316,0.0001712967,0.0004957757,0.0002426957,0.00005072925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001478187,0.0004039808,0.01663827,0.0001761463,0.0005855804,0.000003167031,0.001621739,0.00008623804,0.9528741,0.0008429975,0.01623264,0.009056978],"study_design_scores_gemma":[0.004105138,0.001802964,0.008189064,0.0000617779,0.0002164766,0.000003812722,0.0007425203,0.00002659189,0.756827,0.000124926,0.2277721,0.0001275987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967671,0.02923607,0.00005466918,0.001455299,0.0005704294,0.0006318277,0.00002677721,0.000005438736,0.0003484812],"genre_scores_gemma":[0.9979544,0.000498705,0.00002558257,0.0002587515,0.0005618639,0.00007130356,0.000064347,0.00001763154,0.0005474749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2115395,"threshold_uncertainty_score":0.292102,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3142080073","doi":"10.1038/s41392-021-00507-5","title":"Pyroptosis: mechanisms and diseases","year":2021,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2308,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"Project 211; Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Pyroptosis; Medicine; Immunology; Inflammasome; Inflammation","retraction":null,"screen_n_in":null,"score":{"opus":0.01677021942760649,"gpt":0.2687090103631539,"spread":0.2519387909355474,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006526936,0.0003127433,0.0005435246,0.00006620964,0.0001215297,0.0000465966,0.00007323386,0.0002691226,0.0002085533],"category_scores_gemma":[0.000004069535,0.0002612272,0.000268269,0.0001001774,0.00008041267,0.000005499046,0.00001657864,0.0001342731,0.000002366654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004357015,"about_ca_system_score_gemma":0.00008726412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003058346,"about_ca_topic_score_gemma":9.190243e-7,"domain_scores_codex":[0.9989192,0.0001360902,0.0002397673,0.0004350544,0.00008524099,0.0001846771],"domain_scores_gemma":[0.9996284,0.000007110664,0.00007702105,0.0001698301,0.00004197246,0.00007567386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000337092,0.00005509951,0.000001419934,0.0006689975,0.0004649835,0.000002689836,0.0000383243,4.947605e-7,0.008028551,0.0002044364,0.0001322799,0.990369],"study_design_scores_gemma":[0.0004567213,0.0002184348,0.000004204803,0.000398082,0.0001935424,0.00003284701,0.00009338863,7.466947e-7,0.004115161,0.0001377458,0.9940013,0.0003477739],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003070452,0.9984177,0.0006525572,0.00002917351,0.000176474,0.0002940682,0.00005470728,0.00001750627,0.00005073003],"genre_scores_gemma":[0.0005396699,0.997911,0.00009965737,0.00009266848,0.0001566734,0.00007047439,0.0008715385,0.00004529174,0.0002130002],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9938691,"threshold_uncertainty_score":0.999984,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2068619092","doi":"10.1038/nature13683","title":"Inflammatory caspases are innate immune receptors for intracellular LPS","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2214,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"University of British Columbia; Tsinghua University; National Key Research and Development Program of China; Howard Hughes Medical Institute","keywords":"Innate immune system; Caspase; Receptor; Intracellular; Cell biology; Immune system; Inflammation; Immune receptor; Apoptosis; Biology; Immunology; Programmed cell death; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.00303833343496352,"gpt":0.2130092418197969,"spread":0.2099709083848334,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002249671,0.0001795844,0.0001611529,0.00004771058,0.0001169642,0.00002329545,0.0002281671,0.001144197,0.00003099299],"category_scores_gemma":[0.000342951,0.0001683354,0.0001459065,0.00006869775,0.00005700046,0.00000574453,0.00006901837,0.0005284003,0.00001924142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009962333,"about_ca_system_score_gemma":0.00003553015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003022037,"about_ca_topic_score_gemma":0.00001751147,"domain_scores_codex":[0.9991033,0.00004543781,0.0001960788,0.0002819771,0.00009821221,0.0002749869],"domain_scores_gemma":[0.9992955,0.00001672939,0.0001194864,0.000374217,0.0001496228,0.00004446085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001900657,0.00004227852,0.001756145,0.00008127313,0.00009223419,0.000001912216,0.00006806178,0.00004601105,0.9603207,0.0006811766,0.02988501,0.006835161],"study_design_scores_gemma":[0.0004721387,0.00009682407,0.000971713,0.00001400076,0.00001136917,0.000002595936,0.00008025648,0.00002720012,0.4507502,0.0001096188,0.5472968,0.0001673494],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888474,0.00759456,0.0004480565,0.0005991551,0.0008811892,0.0003083295,0.00002026865,0.00003150029,0.001269546],"genre_scores_gemma":[0.9955029,0.0002141475,0.0003111586,0.0008355481,0.0004332972,0.0000394866,0.0003923726,0.00003975484,0.002231274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5174118,"threshold_uncertainty_score":0.8825092,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3081761942","doi":"10.1056/nejmoa2021372","title":"Colchicine in Patients with Chronic Coronary Disease","year":2020,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2097,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"ZonMw","keywords":"Colchicine; Medicine; Myocardial infarction; Internal medicine; Cardiology; Coronary heart disease; Disease; Coronary disease","retraction":null,"screen_n_in":null,"score":{"opus":0.004761406684979297,"gpt":0.2031713182112391,"spread":0.1984099115262598,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001048108,0.00008885455,0.0001664376,0.00003525923,0.00001486355,0.000002285713,0.0001032309,0.00002733239,0.00006432308],"category_scores_gemma":[0.0001148122,0.00005637549,0.00002533917,0.00007437925,0.00004888225,0.000004855972,0.00001830571,0.0001250703,0.000001483962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001059515,"about_ca_system_score_gemma":0.0001722717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007104884,"about_ca_topic_score_gemma":0.00001906713,"domain_scores_codex":[0.9993716,0.00003317507,0.0002291077,0.00008794825,0.0001652294,0.0001129298],"domain_scores_gemma":[0.9995389,0.000007651794,0.000116242,0.00008054655,0.0000775533,0.0001790884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0131103,0.0001139804,0.8984952,0.00005281541,0.0001220239,0.0001403054,0.0004499312,0.0005969401,0.01652894,0.00001651743,0.01116655,0.05920649],"study_design_scores_gemma":[0.1014958,0.01032868,0.7887064,0.0001847126,0.00007024997,0.00001821937,0.0000677472,0.00002519887,0.0009085904,0.00002931928,0.09801453,0.0001505376],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919122,0.002773753,0.0001492005,0.00480898,0.00009725794,0.00008493116,0.000001544613,0.000001426761,0.0001706467],"genre_scores_gemma":[0.99734,0.0002747731,0.00002999339,0.00108969,0.001156801,4.627271e-7,0.000038812,0.000009885745,0.00005959622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1097888,"threshold_uncertainty_score":0.2298926,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2899885364","doi":"10.1056/nejmoa1809798","title":"Low-Dose Methotrexate for the Prevention of Atherosclerotic Events","year":2018,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1294,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; University of Ottawa; Canadian Respiratory Research Network; McMaster University","funders":"National Heart, Lung, and Blood Institute","keywords":"Methotrexate; Medicine; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01802809714885287,"gpt":0.296314901893154,"spread":0.2782868047443011,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007986541,0.00006874534,0.0001477578,0.00003202654,0.00003935853,0.000001775643,0.000149698,0.00004149224,0.00004413337],"category_scores_gemma":[0.0003150318,0.0000378743,0.00008677218,0.00004694299,0.0000859206,0.000003621364,0.00001638754,0.00005724866,8.795763e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003419787,"about_ca_system_score_gemma":0.00006587848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007901082,"about_ca_topic_score_gemma":0.00001358671,"domain_scores_codex":[0.9993716,0.00005825787,0.0002920233,0.00006110745,0.0001203421,0.00009669106],"domain_scores_gemma":[0.9993034,0.00004385061,0.0002775917,0.0001315153,0.0002063527,0.00003726031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00121537,0.00004992983,0.000588459,0.00002561893,0.0002163053,5.712327e-7,0.0004970785,0.00002355019,0.8112078,0.00003797798,0.004309998,0.1818274],"study_design_scores_gemma":[0.06288891,0.01322707,0.013458,0.0005239274,0.0004343734,0.0001127296,0.0006157157,0.000100481,0.6995943,0.003016163,0.2058391,0.0001892974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756485,0.001991885,0.02008937,0.001250657,0.0006202549,0.0001717385,0.000001255297,0.000001059078,0.0002252902],"genre_scores_gemma":[0.9958603,0.0006125849,0.000440078,0.000148318,0.002101183,0.000001511755,0.000005380924,0.000009005609,0.0008216126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2015291,"threshold_uncertainty_score":0.1544469,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2275879522","doi":"10.1016/j.cell.2015.12.057","title":"NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria","year":2016,"lang":"en","type":"article","venue":"Cell","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1152,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research","keywords":"Biology; Inflammasome; Mitochondrion; Cell biology; NF-κB; NFKB1; Signal transduction; Inflammation; Genetics; Immunology; Transcription factor; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.004892384596637963,"gpt":0.2031330918135887,"spread":0.1982407072169508,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007858484,0.00009688362,0.00008495062,0.00005771174,0.00003743447,0.000005682804,0.000124922,0.0001239215,0.00003574525],"category_scores_gemma":[0.00009171908,0.00007660935,0.0000571637,0.00008184846,0.00004565073,0.00001051313,0.00004676518,0.00003714309,0.00003005716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001100424,"about_ca_system_score_gemma":0.00003891149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006530124,"about_ca_topic_score_gemma":0.000003212354,"domain_scores_codex":[0.9993605,0.00003999201,0.0001840695,0.0001758203,0.00009462135,0.0001449707],"domain_scores_gemma":[0.9994419,0.00001580496,0.0001251451,0.00028012,0.0001106143,0.00002643473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006843879,0.00003397404,0.0004849794,0.00001514826,0.00001035407,3.367605e-7,0.00004136523,0.000004826792,0.9924776,0.00003017748,0.001042569,0.005790243],"study_design_scores_gemma":[0.0007760275,0.000150988,0.009686086,0.00001514634,0.000007842015,5.16981e-7,0.00003518316,0.000005129796,0.9733182,0.00009681725,0.01579581,0.0001122039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908028,0.0001002847,0.003949863,0.0001803254,0.0001288342,0.0001388512,0.000003402261,0.000008594468,0.004687058],"genre_scores_gemma":[0.9966581,0.0001328904,0.0002206066,0.00004312399,0.00008903974,0.00001134859,0.00007374514,0.00001465249,0.002756418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01915934,"threshold_uncertainty_score":0.3124039,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2060198845","doi":"10.1111/j.1365-2249.2006.03261.x","title":"Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1β generation","year":2006,"lang":"en","type":"review","venue":"Clinical & Experimental Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1070,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Augustinus Fonden; Hertz Foundation","keywords":"NALP3; NOD2; Inflammasome; Inflammation; Immunology; Immune system; Autoimmunity; Medicine; Pattern recognition receptor; Interleukin; Biology; Cytokine; Innate immune system","retraction":null,"screen_n_in":null,"score":{"opus":0.04575590370097715,"gpt":0.3911161515768337,"spread":0.3453602478758566,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002795917,0.0003239903,0.001048331,0.00009801158,0.00003651885,0.00001330343,0.0002631865,0.0007437613,0.00004244439],"category_scores_gemma":[0.00006670374,0.0003062881,0.0003389597,0.00009753289,0.000418427,0.000009262836,0.000276338,0.0003160093,0.00001519116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006636899,"about_ca_system_score_gemma":0.0002168907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001896566,"about_ca_topic_score_gemma":0.00006766861,"domain_scores_codex":[0.99735,0.0002704425,0.001534389,0.0005234804,0.00006771118,0.0002539204],"domain_scores_gemma":[0.9988632,0.0000366446,0.0005697958,0.0004639104,0.00003960825,0.00002680226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001234084,0.0004069087,0.0011363,0.001347391,0.0006472127,0.0000217843,0.00007991504,0.00000332246,0.1200513,0.0003873344,0.0008621223,0.8749331],"study_design_scores_gemma":[0.001291492,0.001180081,0.000238714,0.000628606,0.00007811435,0.00003550583,0.00004945762,0.000005820413,0.0257703,0.00001287657,0.9702759,0.0004331735],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1153043,0.8835697,0.000006259554,0.00001303866,0.0003913417,0.0003851921,0.00000797649,0.000005930801,0.0003162283],"genre_scores_gemma":[0.01918247,0.9787515,0.00006500194,0.00002794083,0.0005316117,0.0001184737,0.001066835,0.00003854891,0.000217557],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9694138,"threshold_uncertainty_score":0.9999389,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2113978145","doi":"10.1016/j.jacc.2012.10.027","title":"Low-Dose Colchicine for Secondary Prevention of Cardiovascular Disease","year":2012,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1032,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Internal medicine; Hazard ratio; Colchicine; Clinical endpoint; Acute coronary syndrome; Gastroenterology; Aspirin; Myocardial infarction; Surgery; Cardiology; Randomized controlled trial; Confidence interval","retraction":null,"screen_n_in":null,"score":{"opus":0.007192892760954147,"gpt":0.2403223275636797,"spread":0.2331294348027256,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006037765,0.0001019991,0.0005538707,0.00005604558,0.00003744777,9.665472e-7,0.0002507861,0.00004516484,0.00000274556],"category_scores_gemma":[0.0002024655,0.00007365164,0.001136089,0.0001110529,0.000287045,0.000007613175,0.00007722421,0.00008404026,2.371003e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000120798,"about_ca_system_score_gemma":0.0002193021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002207746,"about_ca_topic_score_gemma":4.711676e-7,"domain_scores_codex":[0.9989634,0.0002271641,0.0004055883,0.00008607102,0.0001354206,0.0001823392],"domain_scores_gemma":[0.9986663,0.00002858266,0.0006123368,0.0003728058,0.0002601834,0.00005980361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01077791,0.0004409578,0.05284652,0.0004612804,0.01485669,0.00001691317,0.0001115704,0.01379365,0.8579694,0.0004180536,0.02546159,0.02284549],"study_design_scores_gemma":[0.007846035,0.005626142,0.193704,0.0001584332,0.002972166,0.0004755102,0.001603793,0.00003296366,0.3619447,0.0005909167,0.4245203,0.0005250639],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899,0.006974029,0.001968073,0.0001407398,0.0004193181,0.0002361304,0.00009354947,8.868548e-7,0.0002672633],"genre_scores_gemma":[0.9984676,0.0006131178,0.0002827324,0.00006646116,0.0004095201,0.000007666707,0.000008034222,0.0000137042,0.0001311577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4960246,"threshold_uncertainty_score":0.3003427,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3033829306","doi":"10.1038/s41421-020-0167-x","title":"Inflammasome activation and regulation: toward a better understanding of complex mechanisms","year":2020,"lang":"en","type":"review","venue":"Cell Discovery","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1001,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Clalit Health Services; Canadian Institute for Advanced Research; Leona M. and Harry B. Helmsley Charitable Trust; Bill and Melinda Gates Foundation; Deutsche Forschungsgemeinschaft; Howard Hughes Medical Institute","keywords":"Inflammasome; AIM2; Caspase; Pyroptosis; Cell biology; Signal transducing adaptor protein; Caspase 1; Effector; Secretion; Multiprotein complex; Signal transduction; Biology; Programmed cell death; Neuroscience; Apoptosis; Inflammation; Immunology; Gene; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.05195290428637296,"gpt":0.2693595755914847,"spread":0.2174066713051118,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007070172,0.0002758616,0.0005992775,0.00007098002,0.00005262019,0.00004878163,0.0001476148,0.000264297,0.00002337583],"category_scores_gemma":[0.00001755314,0.0002528079,0.0002464023,0.0001092622,0.0000745819,0.00001753391,0.0001731905,0.0001208018,0.00000510872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003155798,"about_ca_system_score_gemma":0.0001386171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000252106,"about_ca_topic_score_gemma":8.172168e-7,"domain_scores_codex":[0.9989191,0.00006636362,0.0003824482,0.0003502279,0.0001198623,0.0001620102],"domain_scores_gemma":[0.9993539,0.00001785255,0.0003163894,0.0002536659,0.00002201892,0.00003617401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002835037,0.0001988615,0.00003331985,0.06151577,0.001583951,0.00001697991,0.0006414001,0.00002712567,0.3633324,0.0155883,0.007176473,0.5496019],"study_design_scores_gemma":[0.0003647547,0.0001606465,0.00001523078,0.001046207,0.0002423926,0.000005204969,0.0001879581,0.000007966657,0.01365246,0.001031364,0.9828576,0.0004282381],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003636627,0.970485,0.02594313,0.00007396089,0.0001238648,0.0005496834,0.00004859871,0.00001091466,0.002401133],"genre_scores_gemma":[0.008518459,0.9892826,0.0002333776,0.0000875855,0.0001337088,0.00002314843,0.001262585,0.00004958564,0.0004089487],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9756811,"threshold_uncertainty_score":0.9999924,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2159587574","doi":"10.1056/nejmoa0807865","title":"An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist","year":2009,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":992,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"University of Toronto; Memorial University of Newfoundland","funders":"National Institutes of Health","keywords":"Medicine; Interleukin 1 receptor antagonist; Anakinra; Receptor antagonist; Antagonist; Disease; Immunology; Receptor; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.004121501510238166,"gpt":0.226170194514612,"spread":0.2220486930043738,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002753508,0.000101999,0.000163729,0.00004240491,0.0000470444,0.000005522247,0.0002675689,0.00003461885,0.00003380081],"category_scores_gemma":[0.00008546052,0.00005194839,0.00006124583,0.00007168779,0.0001422351,0.000008135878,0.00001221861,0.0001175505,5.24814e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007187936,"about_ca_system_score_gemma":0.0002343262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006978153,"about_ca_topic_score_gemma":0.000009150627,"domain_scores_codex":[0.9992234,0.00005878979,0.0002971993,0.00008763126,0.000212535,0.0001204357],"domain_scores_gemma":[0.9992506,0.000007306946,0.0002603373,0.0002342073,0.0001263051,0.0001212307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002276947,0.0001329144,0.01560605,0.00002032068,0.00004913254,0.00002015958,0.000710882,0.0001795918,0.899582,0.000146305,0.003919568,0.0773561],"study_design_scores_gemma":[0.07111301,0.02268087,0.2856281,0.001008081,0.0004548945,0.0006626802,0.001986747,0.00005955798,0.3922302,0.0007407688,0.2227755,0.000659651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948549,0.001968887,0.000512926,0.00182771,0.0002327848,0.00006198628,0.00000176251,0.000002125418,0.0005369767],"genre_scores_gemma":[0.9983975,0.0001938435,0.0001179533,0.0003722543,0.0007460265,2.428601e-7,0.000007711872,0.000007033307,0.0001574041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5073519,"threshold_uncertainty_score":0.2118394,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2088164523","doi":"10.1016/j.immuni.2008.02.005","title":"The NLR Gene Family: A Standard Nomenclature","year":2008,"lang":"en","type":"article","venue":"Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":968,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke; Canada Research Chairs; Children's Hospital of Eastern Ontario; University of Ottawa; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Biology; Nomenclature; Gene nomenclature; Computational biology; Gene; Genetics; Gene family; Evolutionary biology; Zoology; Taxonomy (biology); Genome","retraction":null,"screen_n_in":null,"score":{"opus":0.008669964012133448,"gpt":0.2219972532593982,"spread":0.2133272892472648,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001744225,0.0001112406,0.00008556362,0.00001362818,0.0006622974,0.00001763668,0.0002944127,0.0001029466,0.00001112891],"category_scores_gemma":[0.00005329262,0.00008096744,0.00008607463,0.0000730864,0.0001807009,0.000003040985,0.0001338892,0.000176109,0.00002706453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001034562,"about_ca_system_score_gemma":0.00009124139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003732132,"about_ca_topic_score_gemma":0.00002450065,"domain_scores_codex":[0.999342,0.0000730463,0.000129986,0.0001219149,0.0001029636,0.0002300352],"domain_scores_gemma":[0.9992883,0.00001094013,0.00004319104,0.0005434203,0.00008412162,0.00002999236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002761957,0.0000349635,0.001536009,0.000003751404,0.00006874877,0.000005877886,0.0002963091,0.000008217972,0.9822017,0.00009981776,0.0117652,0.003703188],"study_design_scores_gemma":[0.0006659116,0.000257216,0.02422197,0.000002650587,0.000008977392,0.00002927909,0.000349949,0.000003517862,0.3230044,0.0001836951,0.6510643,0.0002082103],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851609,0.005840393,0.0001750326,0.0001519905,0.0001707339,0.0001030094,0.00001310361,0.00001367287,0.008371186],"genre_scores_gemma":[0.9951724,0.001920104,0.0001417661,0.0003109938,0.00007970373,0.00001375646,0.00008559032,0.00001446114,0.002261255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6591974,"threshold_uncertainty_score":0.5093923,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1970436087","doi":"10.1038/nature06664","title":"The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response","year":2008,"lang":"en","type":"article","venue":"Nature","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":927,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Alberta Heritage Foundation for Medical Research; Heart and Stroke Foundation of Canada","keywords":"Innate immune system; Inflammasome; AIM2; NALP3; TLR3; TLR7; MDA5; Biology; Cell biology; TLR9; Interferon; Pattern recognition receptor; Interferon regulatory factors; Toll-like receptor; Immune system; Virology; Inflammation; Immunology; RNA; RNA interference; Gene; Gene expression; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.004492449969380776,"gpt":0.2209103385902936,"spread":0.2164178886209128,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003354131,0.0001729049,0.0001395103,0.00004455404,0.0004381589,0.000045522,0.0001708843,0.0007563675,0.000004059206],"category_scores_gemma":[0.0002403646,0.0001296966,0.00005296037,0.00009223892,0.0002887173,0.00001258041,0.0001092629,0.0006039704,0.000003523853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000623043,"about_ca_system_score_gemma":0.00007404945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000868567,"about_ca_topic_score_gemma":0.00002729728,"domain_scores_codex":[0.9990504,0.0001421659,0.0001755898,0.0002842081,0.00008590066,0.0002617326],"domain_scores_gemma":[0.9994413,0.00003602762,0.00006903082,0.0003126725,0.00008209411,0.0000588552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001734555,0.00001503838,0.0005225592,0.000005438367,0.00004355275,0.000009108823,0.0003023888,2.599074e-7,0.9938665,0.0000163889,0.001013448,0.002470736],"study_design_scores_gemma":[0.001744445,0.0004394579,0.06123303,0.00001251158,0.00001791721,0.0001850864,0.0002648824,0.000004837827,0.7017764,0.00003650262,0.2339691,0.0003157934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838757,0.01451845,0.00000127258,0.0009989551,0.0001814265,0.0001647254,0.00001387633,0.00001361853,0.0002319872],"genre_scores_gemma":[0.992028,0.006109372,0.00005381155,0.0005504488,0.000134717,0.00001001515,0.00005123673,0.00002335545,0.001039066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2920901,"threshold_uncertainty_score":0.5833799,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1605844554","doi":"10.1111/j.1600-065x.2011.01046.x","title":"The inflammasome: an integrated view","year":2011,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":776,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Louis-Jeantet Foundation","keywords":"Inflammasome; Secretion; Cell biology; Proinflammatory cytokine; Biology; Caspase 1; Multiprotein complex; Priming (agriculture); Caspase; Immunology; Inflammation; Programmed cell death; Biochemistry; Apoptosis","retraction":null,"screen_n_in":null,"score":{"opus":0.06380262104007342,"gpt":0.3363025197367327,"spread":0.2724998986966592,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001224827,0.0007829088,0.001824809,0.00005287533,0.0003380805,0.000105751,0.001733219,0.0008868643,0.000190225],"category_scores_gemma":[0.0008630274,0.0003802109,0.001215344,0.000309878,0.0003940716,0.000009065671,0.0004397759,0.0007702981,0.001128834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003317516,"about_ca_system_score_gemma":0.0002193311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008581473,"about_ca_topic_score_gemma":0.00001594914,"domain_scores_codex":[0.9957633,0.001388535,0.001388606,0.0007216473,0.0001075547,0.0006303581],"domain_scores_gemma":[0.9972591,0.00005516905,0.000689528,0.001799042,0.0001067181,0.00009048165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001681191,0.00004742021,2.015889e-7,0.0007318386,0.0001436041,0.00000235499,0.000007400205,1.161243e-8,0.00004139381,0.0003602786,0.0006727606,0.9979759],"study_design_scores_gemma":[0.0001101545,0.0004243075,0.000001887388,0.002092115,0.0002400934,0.00003802369,0.00001496172,8.59653e-8,0.00001926792,0.00004966332,0.9964791,0.0005303699],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00000523323,0.9954829,0.00004052317,0.00001182411,0.0004159635,0.001567866,0.00001270973,0.00003573481,0.002427218],"genre_scores_gemma":[4.928819e-7,0.9953945,0.0001334893,0.0001170233,0.0001690753,0.0007894613,0.000865173,0.00006773468,0.002463007],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9974456,"threshold_uncertainty_score":0.999865,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2028368428","doi":"10.1038/ng.3089","title":"An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome","year":2014,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":735,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; Alberta Children's Hospital; University of Calgary","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Inflammasome; NLRC4; Pyroptosis; AIM2; Caspase 1; Biology; Missense mutation; Innate immune system; Pyrin domain; Mutant; Mutation; Cell biology; Immunology; Inflammation; Genetics; Immune system; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.003831232270680707,"gpt":0.2366487913321476,"spread":0.2328175590614668,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002174982,0.0002579979,0.0001615158,0.00009815546,0.0001830101,0.00007578696,0.0002138556,0.0004618843,0.00001552012],"category_scores_gemma":[0.0001271491,0.0002374422,0.00005319285,0.0001859513,0.00005644973,0.00003127642,0.00004477661,0.0003416598,0.000009905445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003277129,"about_ca_system_score_gemma":0.00007801448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004206693,"about_ca_topic_score_gemma":0.00003094053,"domain_scores_codex":[0.9986023,0.0001140122,0.0002723301,0.0004268881,0.0002790304,0.0003054014],"domain_scores_gemma":[0.9989639,0.00001702318,0.0002244873,0.0004878228,0.0002308138,0.00007593321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002321296,0.00008208073,0.003867759,0.00006396378,0.00007835536,0.000006115621,0.0002784412,0.004126446,0.926639,0.0001409795,0.0001055587,0.06437919],"study_design_scores_gemma":[0.001172199,0.001592671,0.09337205,0.0000583316,0.00003417012,0.0000590706,0.0001654937,0.002269233,0.8862844,0.000188088,0.0142759,0.0005284578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939248,0.0002940853,0.004546032,0.00008721848,0.0002007932,0.0003182847,0.000005810239,0.00004828625,0.0005746807],"genre_scores_gemma":[0.9957129,0.00007778007,0.002810273,0.0001907867,0.0002688011,0.00003445846,0.0007607018,0.00005256836,0.00009169148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0895043,"threshold_uncertainty_score":0.9682611,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1968182403","doi":"10.1016/j.coi.2007.09.002","title":"The inflammasome: a danger sensing complex triggering innate immunity","year":2007,"lang":"en","type":"review","venue":"Current Opinion in Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":699,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Inflammasome; NALP3; Innate immune system; AIM2; Proinflammatory cytokine; Caspase 1; Biology; Interleukin 18; Inflammation; Immunology; Immunity; Cell biology; Immune system; Cytokine","retraction":null,"screen_n_in":null,"score":{"opus":0.08772629359527882,"gpt":0.3806428360255477,"spread":0.2929165424302689,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009173341,0.0006068207,0.001027799,0.0003440906,0.0003659111,0.00007010278,0.0008241251,0.0006870099,0.00001285237],"category_scores_gemma":[0.0002555152,0.0004779946,0.0005068661,0.0004811749,0.0004367841,0.00000815238,0.0007346929,0.001203049,0.00006869945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000107528,"about_ca_system_score_gemma":0.0003369346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002031028,"about_ca_topic_score_gemma":0.0000162646,"domain_scores_codex":[0.9966192,0.0006248862,0.001202723,0.0005601087,0.0001544254,0.0008386523],"domain_scores_gemma":[0.998056,0.0001586263,0.000546894,0.001088362,0.0001053505,0.00004474352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005121638,0.00004159312,0.000004715515,0.001451214,0.000192249,0.000001223396,0.00005016408,0.000001265363,0.000274764,0.0001134328,0.0009680918,0.9968501],"study_design_scores_gemma":[0.0005542908,0.00009006717,0.00007930933,0.002443179,0.00004041938,0.00005516868,0.00007027208,0.000005999857,0.00005383204,0.00002898486,0.9960644,0.0005140412],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003323523,0.9915381,0.0000768028,0.000026953,0.006847143,0.0007321279,0.00001634951,0.00002643717,0.0004037071],"genre_scores_gemma":[0.0000592234,0.9976382,0.00003360278,0.00001099867,0.000501774,0.00006624181,0.001501299,0.00007871616,0.0001100061],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.996336,"threshold_uncertainty_score":0.9997672,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1981649246","doi":"10.1038/nrn3638","title":"Inflammasomes in the CNS","year":2014,"lang":"en","type":"review","venue":"Nature reviews. Neuroscience","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":648,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary; University of Alberta","funders":"","keywords":"Inflammasome; Microglia; Pyroptosis; Neuroscience; Intracellular; Biology; Caspase 1; Programmed cell death; Disease; Immunology; Caspase; Cell biology; Medicine; Inflammation; Apoptosis; Pathology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.02382137407480874,"gpt":0.3464444542648267,"spread":0.322623080190018,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001405684,0.0004903922,0.001127,0.0001305579,0.0001281504,0.00008899552,0.001889807,0.0006858262,0.000007055213],"category_scores_gemma":[0.001215942,0.0002810339,0.0006471399,0.0007883757,0.0001956279,0.000008068148,0.0002309299,0.001236094,0.00007000801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001399751,"about_ca_system_score_gemma":0.0002065478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000152019,"about_ca_topic_score_gemma":0.0000121431,"domain_scores_codex":[0.9969872,0.0007657844,0.0007118562,0.000782876,0.0002881657,0.0004641652],"domain_scores_gemma":[0.9982606,0.00005273605,0.00041148,0.001194123,0.00003368224,0.00004733371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001495343,0.00002503866,0.000006641746,0.003050679,0.000003302527,0.000006647738,0.00001443759,3.76122e-7,0.0001340754,0.0001716684,0.005380576,0.991205],"study_design_scores_gemma":[0.00007127336,0.00007287392,0.00002880669,0.001756115,0.00006180468,0.00006394652,0.000003211235,6.806162e-7,0.00001531029,0.000009648656,0.9975979,0.0003184742],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001313196,0.9958369,0.00001700341,0.00008142584,0.0006425659,0.001151606,0.000007176908,0.000007920717,0.002242284],"genre_scores_gemma":[0.00005787588,0.9965648,0.00002326257,0.00230259,0.0002807885,0.0002068008,0.00008342148,0.00003415469,0.0004463209],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9922173,"threshold_uncertainty_score":0.9999642,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2804559696","doi":"10.1161/circulationaha.118.035202","title":"Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation","year":2018,"lang":"en","type":"article","venue":"Circulation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":641,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Montreal Heart Institute","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Heart, Lung, and Blood Institute","keywords":"Medicine; Inflammasome; Atrial fibrillation; Cardiology; Internal medicine; Signal transduction; Cell biology; Inflammation","retraction":null,"screen_n_in":null,"score":{"opus":0.00936081521459657,"gpt":0.2398318216469826,"spread":0.2304710064323861,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001446381,0.0001236929,0.0001100337,0.00005337052,0.0001480704,0.00003521641,0.00007582741,0.0001473845,0.00003804103],"category_scores_gemma":[0.0001100063,0.0001336689,0.0001464978,0.0001174841,0.00006297498,0.00001434167,0.00003662915,0.00004127801,0.00006745132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001871494,"about_ca_system_score_gemma":0.00005474581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000734518,"about_ca_topic_score_gemma":0.000005724402,"domain_scores_codex":[0.9991429,0.00004956451,0.0002175757,0.000269141,0.0001270282,0.0001937227],"domain_scores_gemma":[0.9994293,0.000007189364,0.0001022536,0.0002502918,0.0001796447,0.0000313282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008543497,0.000002134876,0.00607468,0.000008603779,0.00005251652,2.309714e-7,0.0001702004,0.001649346,0.9817582,0.00006331919,0.00002947206,0.01010583],"study_design_scores_gemma":[0.000823441,0.0001364759,0.0276545,0.00001617063,0.00003384834,0.000004039948,0.00005849717,0.001050838,0.9601471,0.0002824106,0.0095211,0.0002715612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881116,0.0004296952,0.009102419,0.00003551249,0.0003393308,0.0002504618,0.000002280176,0.00002943152,0.001699309],"genre_scores_gemma":[0.9969922,0.0000229222,0.0001841926,0.00002840245,0.002418714,0.000004285829,0.0002551639,0.00002084501,0.00007332648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02161112,"threshold_uncertainty_score":0.545086,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2111586778","doi":"10.1016/j.cell.2012.03.036","title":"DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88","year":2012,"lang":"en","type":"article","venue":"Cell","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":594,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Eye Institute; National Heart, Lung, and Blood Institute","keywords":"Inflammasome; Biology; Macular degeneration; RNA; Alu element; Cell biology; AIM2; Caspase 1; Ribonuclease III; Immunology; Genetics; RNA interference; Gene; Inflammation; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.005257614715215924,"gpt":0.2015955656352339,"spread":0.196337950920018,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001861055,0.0001359204,0.00009034046,0.0000219636,0.000146585,0.00003357864,0.0000871567,0.0001613245,0.00001901726],"category_scores_gemma":[0.00001565726,0.000104716,0.00003699585,0.00005261409,0.0001292656,0.00001239641,0.0001020935,0.000106109,0.00001784233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005050538,"about_ca_system_score_gemma":0.00001487148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001523632,"about_ca_topic_score_gemma":0.000008132301,"domain_scores_codex":[0.9993103,0.00005778841,0.000149081,0.0001746686,0.00007008667,0.0002381138],"domain_scores_gemma":[0.9996187,0.000007599703,0.00005817086,0.0002260495,0.00002814158,0.00006135455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001544795,0.00002371579,0.002748393,0.00001419654,0.00002894552,0.000002580038,0.0003271119,0.000008915047,0.9937178,0.00007056347,0.0003435844,0.002698727],"study_design_scores_gemma":[0.0007382313,0.0000808342,0.01373096,0.000005199874,0.00004515141,0.00002495924,0.0001376939,0.00005457988,0.9377569,0.0001242002,0.0470701,0.0002311831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885892,0.00847382,0.0001097337,0.000183138,0.000148275,0.0001570998,0.000002065475,0.000008087237,0.002328595],"genre_scores_gemma":[0.997565,0.0008385812,0.00005778849,0.0002445585,0.0001474418,0.00001305033,0.0001005318,0.00001850399,0.001014565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05596092,"threshold_uncertainty_score":0.4270194,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2146730043","doi":"10.3109/15563650.2010.495348","title":"Colchicine poisoning: the dark side of an ancient drug","year":2010,"lang":"en","type":"review","venue":"Clinical Toxicology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":593,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Colchicine; Medicine; Pharmacology; Toxicity; Gout; Oral administration; Familial Mediterranean fever; Ketoconazole; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.04621640056165069,"gpt":0.4031584029538672,"spread":0.3569420023922165,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001601293,0.0003328862,0.001359892,0.00004907017,0.00009990345,0.00001217623,0.0008950985,0.001113681,0.00004592881],"category_scores_gemma":[0.001341183,0.0002130868,0.0007771704,0.0001330339,0.0007473108,0.000002460606,0.0003373188,0.0009506317,0.00003535107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008211214,"about_ca_system_score_gemma":0.0005281721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003932031,"about_ca_topic_score_gemma":0.0001039897,"domain_scores_codex":[0.9967937,0.0008403448,0.001295978,0.0005865757,0.0001107492,0.0003726749],"domain_scores_gemma":[0.9975347,0.0003605847,0.0007002217,0.001184639,0.0001123146,0.000107542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005778277,0.0003524781,0.00004931444,0.0005225467,0.0002044967,0.000006654066,0.00001884909,0.000001156943,0.0009340186,0.0001283783,0.005483659,0.9922407],"study_design_scores_gemma":[0.0003902425,0.0008887948,0.00009194428,0.0002038535,0.0002814979,0.00003014192,0.00002948019,0.000001863285,0.000347913,0.0000458231,0.9974496,0.0002388062],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01931537,0.9757016,0.000007183854,0.0001387474,0.001502577,0.0006654469,0.00003144505,0.000009897683,0.002627758],"genre_scores_gemma":[0.0008307122,0.9960729,0.0001319891,0.0008490528,0.0006823937,0.00006994544,0.0003833589,0.00004952292,0.0009301048],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9920018,"threshold_uncertainty_score":0.8689427,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2111994713","doi":"10.1681/asn.2010020143","title":"The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD","year":2010,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":584,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Inflammasome; Inflammation; Kidney disease; Medicine; Kidney; Fibrosis; Acute kidney injury; Caspase 1; Proinflammatory cytokine; Renal function; Immunology; Internal medicine; Pathology; Cancer research","retraction":null,"screen_n_in":null,"score":{"opus":0.003947715916898248,"gpt":0.2299030427523924,"spread":0.2259553268354942,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005399414,0.0001027269,0.0002127995,0.00002106958,0.000168341,0.00001953662,0.0003607536,0.0000790883,0.000002277833],"category_scores_gemma":[0.0002132145,0.00006041393,0.0002200529,0.0001290895,0.000800324,0.000007501532,0.0001664788,0.0002593092,7.802605e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006528868,"about_ca_system_score_gemma":0.00009620186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001472027,"about_ca_topic_score_gemma":0.00004455921,"domain_scores_codex":[0.9991565,0.00008646449,0.0003533658,0.00009641464,0.0001162505,0.0001909523],"domain_scores_gemma":[0.9987511,0.00007269689,0.0006392811,0.0002491252,0.0002475026,0.0000403018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002061421,0.00001177226,0.002509748,0.000003873379,0.0001822706,2.400604e-7,0.0001611262,0.0000161641,0.9804921,0.00008596706,0.008328538,0.008002056],"study_design_scores_gemma":[0.0008819973,0.0009793071,0.1433345,0.0000117779,0.00006462049,0.00009910895,0.000698778,0.00004473249,0.4088583,0.000829135,0.4440677,0.0001300984],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827387,0.0003223846,0.0001789052,0.01646604,0.0001276333,0.0001269835,0.00000220345,0.000001825657,0.00003534993],"genre_scores_gemma":[0.996356,0.0004521673,0.0008736444,0.001909659,0.0002995526,0.000004399563,0.000001548756,0.00001020633,0.00009288827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5716338,"threshold_uncertainty_score":0.2948827,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2566478676","doi":"10.1016/j.bbi.2016.12.014","title":"Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice","year":2016,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":568,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trinity College","funders":"","keywords":"Inflammasome; Pyroptosis; Neuroinflammation; Microglia; Inflammation; Caspase 1; Amyloid (mycology); In vivo; Pathogenesis; Alzheimer's disease; Immunology; Cell biology; In vitro; Neuroscience; Biology; Medicine; Disease; Internal medicine; Biochemistry; Genetics; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.007473376932701372,"gpt":0.2281143568817722,"spread":0.2206409799490708,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002977598,0.0001469453,0.0001476506,0.0000437134,0.0001310803,0.00001709808,0.00008620631,0.00009968782,0.000005965429],"category_scores_gemma":[0.0001671482,0.00009071887,0.00002930566,0.00009384989,0.0003950925,0.00001767441,0.0001031992,0.000130356,0.000001148416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000460168,"about_ca_system_score_gemma":0.00003505696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001495684,"about_ca_topic_score_gemma":0.0001940151,"domain_scores_codex":[0.9992225,0.0001045845,0.0002025194,0.0002029967,0.00007370962,0.0001937451],"domain_scores_gemma":[0.9995327,0.00007854243,0.0001066432,0.0001696573,0.00008585001,0.00002659009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004620554,0.00007583001,0.05577471,0.00002994368,0.00002182506,0.000002082371,0.000294078,3.399166e-7,0.9175632,0.000018872,0.00001154695,0.02574552],"study_design_scores_gemma":[0.001822289,0.0006655395,0.8259271,0.0001535164,0.00005813889,0.00001983572,0.0009975265,0.000002834724,0.1699996,0.00003138475,0.0001442614,0.000177982],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985088,0.0005716156,0.0001947628,0.0001382556,0.00002310659,0.0003624405,0.0000158024,0.000006293455,0.0001789976],"genre_scores_gemma":[0.9995102,0.0001284414,0.00002084574,0.00007624378,0.00002093316,0.00005733021,0.00002735336,0.00001494544,0.0001436917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7701524,"threshold_uncertainty_score":0.3699408,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2791444686","doi":"10.1084/jem.20172222","title":"Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity","year":2018,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":562,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Health and Medical Research Council; Australian Research Council; University of Queensland; Australian Cancer Research Foundation; Fonds de Recherche du Québec - Santé; Kennedy Trust for Rheumatology Research","keywords":"Inflammasome; Tetramer; Caspase; Cell biology; Caspase 1; Caspase 3; Chemistry; AIM2; Caspase 8; Cleavage (geology); Apoptosis; Biophysics; Biology; Programmed cell death; Biochemistry; Enzyme; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.01200095223394119,"gpt":0.2882331801390687,"spread":0.2762322279051275,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000499639,0.000165176,0.0002061293,0.00007961009,0.0001331414,0.000009564224,0.0003621543,0.00007272366,0.0001190197],"category_scores_gemma":[0.00004292157,0.0001046753,0.00005811512,0.00009818721,0.0001587801,0.00001824963,0.0001283093,0.0001353593,0.00002284137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003039917,"about_ca_system_score_gemma":0.00004497933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003176918,"about_ca_topic_score_gemma":0.00000782756,"domain_scores_codex":[0.9990217,0.0001120734,0.0002808855,0.0001325841,0.0002305582,0.0002222175],"domain_scores_gemma":[0.9991903,0.00001088024,0.0001990083,0.0003403854,0.0001207055,0.0001387233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005839776,0.0001219975,0.0000269652,0.000002978881,0.00006669795,0.00001134412,0.004376509,2.368412e-7,0.9898699,0.00003267403,0.002653019,0.002253702],"study_design_scores_gemma":[0.001304262,0.007144165,0.0006310099,0.00003379901,0.00003954871,0.0001968273,0.00271332,0.000007420114,0.9808406,0.00006218038,0.006899242,0.0001276914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964998,0.0005941075,0.0001434454,0.001057705,0.0004574216,0.0001554749,0.00000164082,0.000006480218,0.001083902],"genre_scores_gemma":[0.9965714,0.0001158598,0.0001520549,0.001800164,0.00115429,0.000003077186,0.000002467315,0.000021313,0.000179342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009029363,"threshold_uncertainty_score":0.4268536,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2940679238","doi":"10.1136/annrheumdis-2019-215048","title":"Classification criteria for autoinflammatory recurrent fevers","year":2019,"lang":"en","type":"review","venue":"Annals of the Rheumatic Diseases","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":561,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; Children's Hospital of Western Ontario; SickKids Foundation; Western University","funders":"Executive Agency for Health and Consumers; Rosetrees Trust; Swedish Orphan Biovitrum; E-Rare; Novartis Pharmaceuticals Corporation","keywords":"Medicine; Familial Mediterranean fever; Pharyngitis; Consensus conference; Internal medicine; Disease","retraction":null,"screen_n_in":null,"score":{"opus":0.1213833594175385,"gpt":0.3950284691247774,"spread":0.2736451097072389,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000191388,0.0002847873,0.0007136244,0.00005520856,0.00007315123,0.00002512196,0.0005824851,0.0001782652,0.00002789166],"category_scores_gemma":[0.0003878807,0.000195957,0.001122083,0.00008005133,0.00009536409,0.000005759105,0.0001373571,0.00006439688,0.00002480417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008833433,"about_ca_system_score_gemma":0.000379876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001687151,"about_ca_topic_score_gemma":7.936665e-7,"domain_scores_codex":[0.9985911,0.0001545434,0.0005958631,0.0002891489,0.0001436242,0.0002257555],"domain_scores_gemma":[0.9982334,0.00005851861,0.000663475,0.0008661195,0.0001331233,0.00004535578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000328775,0.00007891638,0.000004961787,0.02098099,0.0004091061,5.113463e-8,0.00001688993,0.000001322812,0.00002125694,0.0001681257,0.03985297,0.9384325],"study_design_scores_gemma":[0.0001707224,0.00008738002,0.0001283789,0.005875648,0.0005186083,0.000001211994,0.00003638971,0.00002483972,0.00007673317,0.0001241871,0.9927031,0.0002527768],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000316644,0.9971615,0.0000332381,0.00008691228,0.0006103947,0.00120427,0.0003479918,0.000008591564,0.0002304674],"genre_scores_gemma":[0.0004042361,0.9974567,0.00002337205,0.00006200485,0.0000597759,0.0002412564,0.0008242757,0.00004522514,0.0008831766],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9528502,"threshold_uncertainty_score":0.7990894,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2808342347","doi":"10.1073/pnas.1722041115","title":"Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":532,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Pyroptosis; Inflammasome; Caspase 1; Microglia; Experimental autoimmune encephalomyelitis; Proinflammatory cytokine; Cell biology; Programmed cell death; Caspase; Neuroinflammation; Multiple sclerosis; Inflammation; Immunology; Biology; Chemistry; Apoptosis; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03839383352469446,"gpt":0.265059864369738,"spread":0.2266660308450435,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004250717,0.00005768186,0.0000803368,0.00009663092,0.00006662239,0.000006070407,0.0001594508,0.00008009315,0.000001814656],"category_scores_gemma":[0.0002204976,0.00004523144,0.00003243192,0.000253381,0.0005274412,0.0000571377,0.0001025032,0.0000450215,1.039257e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007933095,"about_ca_system_score_gemma":0.00001943343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001592787,"about_ca_topic_score_gemma":5.937143e-7,"domain_scores_codex":[0.9992455,0.000005414744,0.0002228695,0.0001460923,0.0002964196,0.00008371846],"domain_scores_gemma":[0.9995444,0.00001237459,0.0002424053,0.00000728276,0.0001827694,0.00001069872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004844217,0.00002686068,0.008591576,0.0000246412,0.000006485687,2.984712e-10,0.0001438871,0.00007785384,0.989709,0.0009965434,0.00003864749,0.0003360545],"study_design_scores_gemma":[0.0003121071,0.00008993436,0.05784985,0.00008260425,0.000003208446,4.012754e-7,0.000127114,0.0007640881,0.9350387,0.005672013,0.00001373494,0.00004617696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988186,0.00004446677,0.000004323917,0.0002307006,0.000007149814,0.000124387,0.000007044632,0.000001290211,0.0007619919],"genre_scores_gemma":[0.9995139,0.00006286026,0.0003055577,0.00005067039,0.00003775755,0.000007389251,7.135322e-7,0.000002620439,0.00001849373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05467024,"threshold_uncertainty_score":0.1943379,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2527001605","doi":"10.1016/j.immuni.2016.08.010","title":"K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria","year":2016,"lang":"en","type":"article","venue":"Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":523,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Graduate School, Technische Universität München; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; National Health and Medical Research Council; Natural Sciences and Engineering Research Council of Canada; European Research Council; Elitenetzwerk Bayern; Tehran University of Medical Sciences and Health Services; Australian Research Council; Deutsches Zentrum für Infektionsforschung; European Synchrotron Radiation Facility; Deutsche Forschungsgemeinschaft; TUM Universitätsstiftung; Bayerisches Staatsministerium für Wissenschaft, Forschung und Kunst","keywords":"Inflammasome; Efflux; Biology; Mitochondrion; Cell biology; Biochemistry; Immunology; Inflammation","retraction":null,"screen_n_in":null,"score":{"opus":0.005861632127103591,"gpt":0.2096041229239265,"spread":0.2037424907968229,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002343738,0.0002218727,0.0001510303,0.00004913382,0.0001931226,0.00003486843,0.0003493294,0.0002148355,0.00008148079],"category_scores_gemma":[0.0003137999,0.0001759333,0.0001204555,0.00008046033,0.00008607168,0.00001590777,0.0002044799,0.0001474863,0.00007824488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003377425,"about_ca_system_score_gemma":0.00006190572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001040611,"about_ca_topic_score_gemma":0.00002336013,"domain_scores_codex":[0.998757,0.0001552407,0.0002861283,0.0002950889,0.0001412604,0.0003653003],"domain_scores_gemma":[0.9991308,0.00003186068,0.0001373297,0.0005128795,0.0001236569,0.00006340573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008863826,0.00005867806,0.001752508,0.00000923992,0.00005852028,6.43055e-7,0.00006323286,0.000006549442,0.9889004,0.00004404509,0.003641063,0.005376435],"study_design_scores_gemma":[0.001022229,0.0001425026,0.004739262,0.00002767285,0.00001050247,0.000002491921,0.0001525211,0.000005598081,0.9277148,0.0001124161,0.06578127,0.0002887811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912969,0.0004819799,0.00560796,0.0003667842,0.0002077099,0.0002152232,0.00001823341,0.00003581317,0.001769375],"genre_scores_gemma":[0.9967003,0.0002098105,0.0003848288,0.0001934968,0.0001395553,0.00003966671,0.0003028663,0.00003852252,0.001990905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0621402,"threshold_uncertainty_score":0.7174352,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2122621644","doi":"10.1038/ng.285","title":"Common variants in the NLRP3 region contribute to Crohn's disease susceptibility","year":2008,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":523,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Montreal Heart Institute; Toronto Western Hospital; Centre Hospitalier Universitaire de Sherbrooke; Royal Victoria Regional Health Centre; Université de Montréal; Université du Québec à Chicoutimi; Mount Sinai Hospital; McGill University Health Centre; Royal Victoria Hospital; University of Toronto; Ontario Institute for Cancer Research; McGill University and Génome Québec Innovation Centre; Jewish General Hospital; Montreal General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases","keywords":"Single-nucleotide polymorphism; Biology; Odds ratio; Genetics; Crohn's disease; Disease; ATG16L1; Genome-wide association study; Case-control study; Inflammatory bowel disease; Genotype; Gene; Medicine; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.007972779966945884,"gpt":0.249411480508178,"spread":0.2414387005412322,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001938224,0.0001582537,0.0001317962,0.00003813444,0.0001406602,0.00001704974,0.0003927841,0.0002796327,0.000005917591],"category_scores_gemma":[0.000167054,0.0001251206,0.00008674925,0.0001774527,0.00007739343,0.000002661988,0.0001039907,0.0003051548,0.00001268986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001514284,"about_ca_system_score_gemma":0.00008639693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001267144,"about_ca_topic_score_gemma":0.0001545276,"domain_scores_codex":[0.9988831,0.0001242283,0.0001965421,0.0003210763,0.0001756268,0.0002993938],"domain_scores_gemma":[0.9990617,0.00001511732,0.00004561887,0.0007022839,0.00009297717,0.00008232678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002121663,0.0008532893,0.8319555,0.00007118331,0.0001051026,0.00112445,0.001301704,0.0009476884,0.06651918,0.0002635967,0.08739188,0.007344746],"study_design_scores_gemma":[0.0006738517,0.0001391716,0.9344243,0.000008389104,0.00001353171,0.00002501964,0.00006147401,0.00002598208,0.007064094,0.0001697552,0.0571916,0.0002027787],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939359,0.003677356,0.0001590371,0.001101523,0.0002024755,0.0004149822,0.0000239549,0.000007672952,0.000477089],"genre_scores_gemma":[0.9952812,0.0006447799,0.0001035903,0.003409226,0.0001714399,0.0000219194,0.0001556876,0.00001551312,0.000196663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1024688,"threshold_uncertainty_score":0.5102268,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2018983895","doi":"10.1016/j.immuni.2010.02.012","title":"Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases","year":2010,"lang":"en","type":"article","venue":"Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":510,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital; University of British Columbia; McGill University","funders":"Canadian Institutes of Health Research; Canada Research Chairs; McGill University Health Centre","keywords":"Azoxymethane; Inflammasome; Colitis; Inflammation; Caspase; Cancer research; Biology; Colorectal cancer; Apoptosis; Cancer; Immune system; Intestinal mucosa; Immunology; Programmed cell death; Medicine; Internal medicine; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.004571074976026062,"gpt":0.2279315943475893,"spread":0.2233605193715633,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002829776,0.000133319,0.0001617301,0.00001941118,0.0001903472,0.00002059014,0.0002091498,0.0001392097,0.00004701469],"category_scores_gemma":[0.0003686567,0.0001109799,0.00005713221,0.00006112405,0.0004463826,0.000005950544,0.00009846882,0.0002726879,0.000001411299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001004392,"about_ca_system_score_gemma":0.0001379028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002264514,"about_ca_topic_score_gemma":0.003973867,"domain_scores_codex":[0.9991966,0.0001518704,0.000207324,0.0001288021,0.0000885066,0.0002268244],"domain_scores_gemma":[0.9993342,0.00007111639,0.0001398572,0.0002331344,0.0001783198,0.00004332661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003787978,0.00009368784,0.03920235,0.00001875655,0.0001468557,0.0000015002,0.000158219,0.000001686682,0.9542143,0.0001269845,0.002147413,0.003509384],"study_design_scores_gemma":[0.001742698,0.0003136007,0.4612352,0.00002434879,0.0000517519,0.00002457415,0.000480208,0.00002659635,0.5219924,0.00005432351,0.01382962,0.0002247104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966504,0.002248658,0.00001005124,0.0001271471,0.0001465139,0.0002277065,0.0002559986,0.000009679384,0.0003238294],"genre_scores_gemma":[0.9991701,0.0003311069,0.000006970316,0.0001529015,0.00003494217,0.00005621157,0.0001478823,0.00001424628,0.00008564827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.432222,"threshold_uncertainty_score":0.452563,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2913004193","doi":"10.1016/j.abb.2019.02.008","title":"NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways","year":2019,"lang":"en","type":"review","venue":"Archives of Biochemistry and Biophysics","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":476,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada; University of Calgary","keywords":"Inflammasome; Pyrin domain; Pyroptosis; Innate immune system; Signal transducing adaptor protein; Cell biology; Pattern recognition receptor; Receptor; AIM2; Biology; Signal transduction; Caspase 1; Effector; Nod; Non canonical; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01443494681458776,"gpt":0.2521266863066043,"spread":0.2376917394920165,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001527729,0.0004961073,0.001404054,0.000042286,0.00005579296,0.00001452489,0.0002740461,0.0003416127,0.000004429855],"category_scores_gemma":[0.00005678386,0.0003934947,0.0004061813,0.000108195,0.0006676834,0.000006443986,0.0004656119,0.0002759321,6.920753e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004589937,"about_ca_system_score_gemma":0.0004107443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006329383,"about_ca_topic_score_gemma":5.63856e-7,"domain_scores_codex":[0.9981982,0.00007905679,0.000716769,0.0006090333,0.0001193189,0.000277668],"domain_scores_gemma":[0.9986699,0.0001257303,0.000526464,0.0005224214,0.00004743818,0.0001081045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006576658,0.00008986525,0.00003881048,0.1797125,0.0005233251,0.000002003644,0.00008777312,1.011274e-7,0.2647693,0.00003144112,0.0001182972,0.5545608],"study_design_scores_gemma":[0.001127982,0.0008312573,0.0000248989,0.1016333,0.001314897,0.00007771258,0.0002149902,0.00000785985,0.2851958,0.0001170845,0.6079532,0.001501034],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03102772,0.9677895,0.00000935264,0.00001531956,0.00006636218,0.0004015013,0.0001517322,0.000004373313,0.0005341129],"genre_scores_gemma":[0.007101513,0.9917039,0.0001943506,0.00005490156,0.000109047,0.00002324798,0.000635514,0.00003887862,0.0001386541],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6078349,"threshold_uncertainty_score":0.9998517,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2326861977","doi":"10.1097/00005792-200209000-00002","title":"The TNF Receptor-Associated Periodic Syndrome (TRAPS)","year":2002,"lang":"en","type":"review","venue":"Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":454,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Missense mutation; Medicine; Familial Mediterranean fever; Mutation; Genetics; Penetrance; Tumor necrosis factor receptor 1; Point mutation; Amyloidosis; Phenotype; Tumor necrosis factor receptor; Receptor; Biology; Internal medicine; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.0198821506229412,"gpt":0.2786565662404933,"spread":0.2587744156175521,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004340378,0.0003904699,0.0008768165,0.00006290296,0.0002704913,0.00002087823,0.0005153687,0.0004502336,0.0003630103],"category_scores_gemma":[0.0003708879,0.0002258076,0.0003393111,0.000227972,0.0003101178,0.000001482119,0.00009254779,0.0003392102,0.0002427495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003598848,"about_ca_system_score_gemma":0.0001010233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001202046,"about_ca_topic_score_gemma":0.000010372,"domain_scores_codex":[0.998267,0.0001933817,0.0005366024,0.000375716,0.0002211603,0.0004061609],"domain_scores_gemma":[0.998889,0.00004532096,0.0002866224,0.0006422727,0.00006717828,0.00006961006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004423205,0.00002704437,0.000002696747,0.0006336996,0.0003545665,0.00001134195,0.00004039965,4.048005e-8,0.00005053186,0.00001383523,0.0807914,0.91807],"study_design_scores_gemma":[0.000330136,0.0003835653,0.000007218942,0.00208645,0.0002750382,0.00006352057,0.00005123955,3.9301e-7,0.000005464631,0.000004196521,0.9965332,0.000259617],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001179498,0.9944867,0.000003154504,0.0003250669,0.000756154,0.0004067986,0.0000161355,0.00001882764,0.003869215],"genre_scores_gemma":[0.0001294402,0.9848341,0.000002855593,0.000137108,0.0003150206,0.00008718018,0.001089568,0.00006058755,0.01334412],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9178104,"threshold_uncertainty_score":0.9208169,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2120052164","doi":"10.4049/jimmunol.1200312","title":"Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1β Production","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":451,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity; Trinity College","funders":"Versus Arthritis","keywords":"Inflammasome; Untranslated region; microRNA; Microvesicles; Cell biology; Three prime untranslated region; Downregulation and upregulation; Inflammation; Endogeny; Biology; Messenger RNA; Chemistry; Immunology; Gene; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.006829105092810557,"gpt":0.2198570316355719,"spread":0.2130279265427613,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001077992,0.0001430595,0.0001700373,0.00004882739,0.0002543754,0.0000195322,0.0002123223,0.0001301609,0.000008012181],"category_scores_gemma":[0.0002059766,0.00008319812,0.00005928914,0.00006714672,0.0003730663,0.00002605529,0.0001635508,0.0002835514,0.000005020454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009581076,"about_ca_system_score_gemma":0.00003601565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009825081,"about_ca_topic_score_gemma":0.000004200484,"domain_scores_codex":[0.9989337,0.0002492496,0.0003282721,0.0001010568,0.00008460176,0.0003030752],"domain_scores_gemma":[0.9992025,0.00003696759,0.0003183081,0.0002868218,0.0001211927,0.00003418806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002589617,0.00003509905,0.001898683,0.00001004424,0.0002123486,9.882746e-7,0.0009092863,0.000007615985,0.9845517,0.00008064442,0.001105046,0.01092953],"study_design_scores_gemma":[0.001848896,0.000809089,0.1159231,0.00005339419,0.0002239602,0.003324817,0.003050142,0.000007320428,0.6651432,0.0005731035,0.2087124,0.0003305949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9591506,0.03749805,0.00002608051,0.002445834,0.0005427236,0.0001208588,0.000001020049,0.000003737206,0.0002111042],"genre_scores_gemma":[0.9926903,0.006078412,0.00006333254,0.0001578316,0.0004713638,0.000002942516,0.000003805553,0.00001666554,0.0005154005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3194086,"threshold_uncertainty_score":0.3392721,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1970837608","doi":"10.1016/j.chom.2014.07.002","title":"Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens","year":2014,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":440,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Inflammasome; Biology; Salmonella enterica; Innate immune system; Intestinal epithelium; Caspase 1; Microbiology; Proinflammatory cytokine; Caspase; Cell biology; Intracellular; Pyroptosis; Epithelium; Salmonella; Programmed cell death; Immune system; Apoptosis; Immunology; Inflammation; Bacteria","retraction":null,"screen_n_in":null,"score":{"opus":0.00434469465684373,"gpt":0.1958256616587479,"spread":0.1914809670019042,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002052699,0.0002902297,0.0003071524,0.00007976747,0.00009807113,0.00003079421,0.0002812089,0.0002802939,0.0000788367],"category_scores_gemma":[0.0001343516,0.0002865575,0.0002131827,0.0001087524,0.0001667248,0.00001354189,0.0001823724,0.0001171066,0.00004789352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002100406,"about_ca_system_score_gemma":0.0001323998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004142737,"about_ca_topic_score_gemma":0.00005392138,"domain_scores_codex":[0.9984582,0.0001368263,0.0004520726,0.000414815,0.0001306924,0.000407366],"domain_scores_gemma":[0.9989912,0.00003866948,0.0002614544,0.0004719814,0.0001481692,0.00008850908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002068316,0.0001163127,0.001414575,0.00005349797,0.00003462705,0.000002843259,0.0001460442,0.00002000402,0.9959145,0.00001035307,0.0007508873,0.001329494],"study_design_scores_gemma":[0.001324596,0.0003030016,0.002361318,0.00002709132,0.0000317036,0.000004872319,0.00009145265,0.00001381226,0.9169131,0.000005281623,0.07862141,0.000302373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977813,0.0002281758,0.000269786,0.00007192753,0.0004399013,0.0002328671,0.0001051827,0.00001820638,0.0008526001],"genre_scores_gemma":[0.9971997,0.0003033611,0.0002720302,0.0002708944,0.0005202974,0.00002021546,0.001073793,0.00005109345,0.0002885936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07900144,"threshold_uncertainty_score":0.9999586,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2593240146","doi":"10.1164/rccm.201609-1830oc","title":"Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma","year":2017,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":435,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Inflammasome; Medicine; Immunology; Pyrin domain; Asthma; Caspase 1; Pathogenesis; Inflammation","retraction":null,"screen_n_in":null,"score":{"opus":0.01059722569309658,"gpt":0.2923876950684552,"spread":0.2817904693753586,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006883955,0.0001871134,0.0004180513,0.0001339029,0.000200099,0.00003900065,0.0003149614,0.00009130174,0.00001425262],"category_scores_gemma":[0.002800907,0.0001497784,0.0000972778,0.00004936138,0.0010043,0.00002477962,0.00008806697,0.0002244589,0.000001007393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002297486,"about_ca_system_score_gemma":0.0001648525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002628974,"about_ca_topic_score_gemma":0.00009186465,"domain_scores_codex":[0.9985241,0.0001635983,0.0005140203,0.0002371162,0.0002475574,0.0003136381],"domain_scores_gemma":[0.9986154,0.0001647533,0.0002832737,0.0003538797,0.0003946209,0.0001880941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01030561,0.0001188685,0.04768144,0.0002110193,0.0001352724,0.0002665791,0.001328658,0.000007625799,0.775475,0.0003843009,0.0006209498,0.1634646],"study_design_scores_gemma":[0.01985559,0.06364284,0.2710716,0.001022464,0.0003000484,0.0004144741,0.07149465,0.00001444359,0.09349272,0.0007760266,0.4764636,0.001451571],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900453,0.007851303,0.0001129231,0.001205173,0.0001738439,0.000130601,0.00003483345,0.000002837576,0.0004432007],"genre_scores_gemma":[0.9980227,0.000269392,0.0001226183,0.001088735,0.0004091926,0.00001225415,0.000008284317,0.00002055865,0.00004631454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6819823,"threshold_uncertainty_score":0.6107786,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2142145460","doi":"10.1002/ibd.21478","title":"NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis","year":2010,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":430,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Alberta Heritage Foundation for Medical Research; Crohn's and Colitis Foundation of America","keywords":"Inflammasome; Innate immune system; Immunology; Colitis; Nod; Immune system; Cytokine; Biology; Inflammation; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.004644563360345754,"gpt":0.2144857959045641,"spread":0.2098412325442184,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002612771,0.0002092788,0.0001658916,0.000120954,0.0000900682,0.00003535691,0.0004376378,0.0001475146,0.00007771116],"category_scores_gemma":[0.000353346,0.0001726818,0.0001535797,0.0001476952,0.0002341844,0.00002337337,0.0001042616,0.0001989296,0.00002092273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007960507,"about_ca_system_score_gemma":0.0001504002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002283897,"about_ca_topic_score_gemma":0.0002271221,"domain_scores_codex":[0.9986707,0.0001029429,0.0004195623,0.0002789504,0.0002401168,0.0002877449],"domain_scores_gemma":[0.9989805,0.0000446284,0.0001789501,0.0006154754,0.000115637,0.00006481526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003783046,0.0001723621,0.290268,0.00007342797,0.00004177137,0.00001355868,0.0005856606,0.0001965955,0.7025388,0.001309356,0.0007874448,0.0036347],"study_design_scores_gemma":[0.0008046639,0.0001153018,0.9290463,0.00003234267,0.00003398264,0.00001433301,0.0007101758,0.00009488443,0.05592889,0.0008173616,0.01213341,0.0002683],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971482,0.0006918709,0.00001549909,0.0001179589,0.0001255205,0.0002989758,0.0000329391,0.00001790826,0.001551158],"genre_scores_gemma":[0.9992107,0.00006065737,0.00007945138,0.000119342,0.0001827184,0.00007856409,0.0001762184,0.00002418396,0.00006814495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6466099,"threshold_uncertainty_score":0.7041758,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2884318134","doi":"10.1016/j.atherosclerosis.2018.07.014","title":"Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions","year":2018,"lang":"en","type":"review","venue":"Atherosclerosis","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":426,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; University of Ottawa; McGill University Health Centre; University of Alberta","funders":"Genentech; Lantheus Medical Imaging; Novo Nordisk; University of Ottawa; Sanofi; Amgen; Pfizer; Heart and Stroke Foundation of Canada","keywords":"Inflammation; Medicine; Disease; Pathogenesis; Coronary artery disease; Randomized controlled trial; Observational study; Clinical trial; Systemic inflammation; Bioinformatics; Immunology; Internal medicine; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.03943232081782089,"gpt":0.300189999059256,"spread":0.2607576782414351,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005369404,0.0002928864,0.0006963169,0.0001216699,0.00005510465,0.0000181566,0.0004318366,0.0003265698,0.00001666617],"category_scores_gemma":[0.00005028723,0.000211566,0.0006233079,0.0002714272,0.0002280782,0.000005398845,0.000129849,0.000109162,0.000005229239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001057634,"about_ca_system_score_gemma":0.00005744004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003822504,"about_ca_topic_score_gemma":0.00006485979,"domain_scores_codex":[0.9982016,0.0003375298,0.0007977104,0.0003150381,0.0001478888,0.0002001979],"domain_scores_gemma":[0.9986863,0.00005043357,0.0005693397,0.0005952403,0.00007880747,0.00001987338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001986231,0.0002538006,0.001603811,0.006371969,0.0004674016,5.013965e-8,0.001195131,0.000002146325,0.1453491,0.0002232055,0.00004948869,0.844464],"study_design_scores_gemma":[0.001949373,0.002375745,0.04813901,0.02788527,0.002951666,0.00001402573,0.00271159,0.00002356258,0.02948176,0.0004528572,0.8822607,0.001754421],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08658303,0.912566,0.00002119062,0.000008780363,0.0000437521,0.000569463,0.00006290209,0.00000422926,0.0001406687],"genre_scores_gemma":[0.06206299,0.9374776,0.00005064921,0.00001471835,0.00005627724,0.0001589589,0.0001001268,0.00004415277,0.00003447336],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8822112,"threshold_uncertainty_score":0.8627412,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2096317294","doi":"10.4049/jimmunol.0904145","title":"NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":424,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Canadian Institutes of Health Research; Multiple Sclerosis Society; National Multiple Sclerosis Society","keywords":"Experimental autoimmune encephalomyelitis; NALP3; Astrogliosis; Inflammasome; Immunology; Multiple sclerosis; Pyrin domain; Innate immune system; Caspase 1; Encephalomyelitis; Acquired immune system; Myelin oligodendrocyte glycoprotein; Myelin; CD8; Interleukin 17; Biology; Medicine; Inflammation; Immune system; Neuroscience; Central nervous system","retraction":null,"screen_n_in":null,"score":{"opus":0.005552694106910372,"gpt":0.2559756261178948,"spread":0.2504229320109844,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001004653,0.00009865403,0.0001597256,0.00004716521,0.0001124672,0.0000100093,0.0003669938,0.0001100603,0.00002007403],"category_scores_gemma":[0.0003986424,0.00005973611,0.00004261093,0.00004882367,0.0003586792,0.000009343592,0.0001112599,0.0003197491,0.000001032867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006001741,"about_ca_system_score_gemma":0.0001235059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001692436,"about_ca_topic_score_gemma":0.000017009,"domain_scores_codex":[0.9989516,0.000249295,0.0004328745,0.00007367428,0.0001083669,0.0001841875],"domain_scores_gemma":[0.9993804,0.0001812015,0.0001756808,0.000182153,0.00006662094,0.00001393473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003965571,0.00006579673,0.0004562411,0.000002615733,0.00004561498,0.000001843979,0.006187714,4.999356e-7,0.9900749,0.00008923817,0.00005325907,0.002625683],"study_design_scores_gemma":[0.0007867338,0.0005016223,0.03398276,0.00001535524,0.00001342876,0.0002744631,0.01456659,0.000004729944,0.945166,0.0001029882,0.004493362,0.00009197309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850566,0.01402133,0.0000316711,0.0004474501,0.0001425613,0.0000627488,0.000002818098,0.000001133023,0.0002336895],"genre_scores_gemma":[0.9990723,0.0003222676,0.0004385722,0.00009199644,0.00003844048,0.000004887554,0.000004754154,0.000007362812,0.00001938667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04490894,"threshold_uncertainty_score":0.2435968,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1954263225","doi":"10.4049/jimmunol.1002046","title":"IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":417,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Biotechnology Research Institute","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Takeda Oncology; National Cancer Institute; Yale University; National Institutes of Health; American Lebanese Syrian Associated Charities; National Institute of Allergy and Infectious Diseases; Vlaamse regering; St. Jude Children's Research Hospital","keywords":"Inflammasome; Azoxymethane; Inflammation; Proinflammatory cytokine; Carcinogenesis; Colorectal cancer; Cancer research; Nod; Effector; Immunology; Cancer; Medicine; Internal medicine; Endocrinology","retraction":null,"screen_n_in":null,"score":{"opus":0.005786981260014884,"gpt":0.2029850456915568,"spread":0.1971980644315419,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005576268,0.000110785,0.0001460617,0.00006544573,0.0001441503,0.000008605868,0.0003327055,0.0001240929,0.00001378928],"category_scores_gemma":[0.0003304691,0.00006480655,0.0001255838,0.0001124441,0.0003152391,0.0000228492,0.00007807034,0.0004151646,0.000003762386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001498275,"about_ca_system_score_gemma":0.0001263681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001003444,"about_ca_topic_score_gemma":0.00005207839,"domain_scores_codex":[0.9990619,0.0001745721,0.0004158765,0.00007442077,0.0001159222,0.0001572766],"domain_scores_gemma":[0.9986808,0.00001109542,0.0006725926,0.0002877162,0.0003340817,0.00001376804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000562197,0.00004233604,0.0001999177,0.000008579355,0.00009352092,4.098553e-7,0.0002393807,0.0001086757,0.99101,0.00002330653,0.0002298298,0.007481921],"study_design_scores_gemma":[0.0006119988,0.0005365816,0.009443234,0.00001659825,0.00003565709,0.0004464053,0.0005877202,0.00002046959,0.9781908,0.00007956334,0.00995456,0.00007643617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970943,0.0003000791,0.00005747566,0.0006471997,0.001183019,0.0002903345,0.000002537503,0.000003682695,0.0004214002],"genre_scores_gemma":[0.99928,0.0003478354,0.00002756423,0.0000508269,0.00018346,0.000007543632,0.00000630863,0.00001030813,0.00008611421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01281915,"threshold_uncertainty_score":0.2642735,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2058493175","doi":"10.1038/cdd.2008.91","title":"Cell death in the host response to infection","year":2008,"lang":"en","type":"review","venue":"Cell Death and Differentiation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":403,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Thomas Jefferson University","keywords":"Pyroptosis; Programmed cell death; Autophagy; Immune system; Biology; Effector; Innate immune system; Apoptosis; Immunology; Pathogen; Inflammation; Cell; Cell biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01583532494273296,"gpt":0.2613312882517104,"spread":0.2454959633089774,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001539028,0.0002604772,0.0003206347,0.000141621,0.0001108242,0.00004562809,0.000128869,0.0002849636,0.000007181013],"category_scores_gemma":[0.00004203396,0.0001892445,0.0001684935,0.0001248377,0.00001319495,0.000004577736,0.00006266457,0.0001531881,0.00002811813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002059463,"about_ca_system_score_gemma":0.00008055238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003252455,"about_ca_topic_score_gemma":0.00001535181,"domain_scores_codex":[0.9987932,0.00029645,0.0002784801,0.0003234206,0.00009871249,0.0002097224],"domain_scores_gemma":[0.9994711,0.00003312963,0.0001230947,0.0003000206,0.00002906912,0.00004353772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002180047,0.002325003,0.02389448,0.01744285,0.0003583497,0.00007121137,0.003747181,0.0000314172,0.04538067,0.0001753395,0.01401001,0.8903834],"study_design_scores_gemma":[0.0004289254,0.0002272005,0.01759002,0.0002331736,0.0001012504,0.0000142099,0.00001940225,0.000003975571,0.0007957428,0.000007388082,0.9802632,0.0003155204],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.214509,0.7836769,0.0001689178,0.000009718062,0.0001229662,0.0005496944,0.00001092156,0.000006150628,0.0009458289],"genre_scores_gemma":[0.050427,0.948025,0.00001660094,0.00008611548,0.00008541191,0.00009788819,0.0006213682,0.00002360535,0.0006170182],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9662532,"threshold_uncertainty_score":0.7717168,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2164450207","doi":"10.1002/art.10509","title":"Association of mutations in the <i>NALP3/CIAS1/PYPAF1</i> gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis","year":2002,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":374,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Medicine; Family history; Genetics; Compound heterozygosity; Dermatology; Internal medicine; Gene; Phenotype; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.009880114101742004,"gpt":0.2146785582802718,"spread":0.2047984441785298,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002885514,0.0001439521,0.0001892168,0.00005260757,0.0001431265,0.00003681096,0.00007240403,0.00008841558,0.00001535318],"category_scores_gemma":[0.0001004497,0.000127548,0.00004564098,0.00017423,0.00007054656,0.000020932,0.00005923466,0.0001182047,0.000006483665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001894117,"about_ca_system_score_gemma":0.00001756436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002866036,"about_ca_topic_score_gemma":0.002163122,"domain_scores_codex":[0.9989154,0.0001786216,0.0002694946,0.0002135459,0.0001945531,0.0002284253],"domain_scores_gemma":[0.9994523,0.00006690283,0.0001738487,0.0001873902,0.00009353325,0.00002603756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001508715,0.000690872,0.154496,0.0001310246,0.0004377045,0.00005515675,0.008987891,0.0004874029,0.6029375,0.0008686114,0.008546364,0.2222106],"study_design_scores_gemma":[0.02239843,0.002322233,0.5634838,0.002059032,0.0003279926,0.000686679,0.005492289,0.005642372,0.3683381,0.0009590087,0.02532773,0.00296229],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936255,0.0049438,0.00009233423,0.0006104936,0.0000706202,0.0002343671,0.00002965567,0.000008708997,0.0003845077],"genre_scores_gemma":[0.9914166,0.007937196,0.0002561291,0.000174338,0.00002492447,0.00002866302,0.00006912133,0.00001566952,0.00007731378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4089878,"threshold_uncertainty_score":0.5201258,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2995981280","doi":"10.1016/j.tins.2019.11.005","title":"Fiery Cell Death: Pyroptosis in the Central Nervous System","year":2019,"lang":"en","type":"review","venue":"Trends in Neurosciences","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":359,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta; Women and Children’s Health Research Institute","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Pyroptosis; Central nervous system; Neuroscience; Nervous system; Programmed cell death; Psychology; Biology; Apoptosis; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.04983649402700782,"gpt":0.315787087286854,"spread":0.2659505932598462,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002819691,0.000291372,0.0005163203,0.0002388597,0.00006500772,0.00007294821,0.001016674,0.0002129798,0.000006642607],"category_scores_gemma":[0.00002541621,0.0001856642,0.0002833128,0.0006401317,0.00009707194,0.000006451911,0.0001270151,0.0002470118,0.0000133363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002234219,"about_ca_system_score_gemma":0.0001232134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005366471,"about_ca_topic_score_gemma":0.00004200016,"domain_scores_codex":[0.9980535,0.0002985087,0.0004131372,0.0005493828,0.0001998189,0.0004856716],"domain_scores_gemma":[0.9992548,0.00003397474,0.0001686441,0.0005066785,0.000008522733,0.00002733189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001255039,0.0001856656,0.0009066057,0.003913411,0.00001136668,0.00005698361,0.0002020985,0.00006493137,0.0006445902,0.00009753571,0.001162345,0.9927419],"study_design_scores_gemma":[0.0001721835,0.0001912709,0.0008924838,0.0006127664,0.00005591202,0.00002830022,0.0002153007,0.00002025032,0.0001299741,0.000001065124,0.9973482,0.0003322144],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00718876,0.9824614,0.000001766036,0.00002019041,0.001302953,0.0002606504,0.00001963046,0.000008226356,0.008736431],"genre_scores_gemma":[0.02912766,0.9689415,0.000007359349,0.00008465917,0.00008892914,0.00006057916,0.00007560726,0.00002038075,0.001593324],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.996186,"threshold_uncertainty_score":0.7571168,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2069360787","doi":"10.1371/journal.ppat.1000559","title":"Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases","year":2009,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":358,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; McGill University; Institut National de la Recherche Scientifique; McGill University Health Centre","funders":"National Institutes of Health; Conselho Nacional de Desenvolvimento Científico e Tecnológico; McGill University Health Centre; National Heart, Lung, and Blood Institute; McGill University; Bill and Melinda Gates Foundation; Howard Hughes Medical Institute","keywords":"LYN; Inflammasome; Syk; Hemozoin; Cell biology; Kinase; Biology; Proto-oncogene tyrosine-protein kinase Src; Tyrosine kinase; Kinome; Inflammation; Signal transduction; Immunology; Plasmodium falciparum; Malaria","retraction":null,"screen_n_in":null,"score":{"opus":0.00865399617519145,"gpt":0.2171232675473914,"spread":0.2084692713721999,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009055454,0.0002011031,0.0001564093,0.00002171615,0.0002042676,0.00005074726,0.0001937237,0.0001469448,0.00002928374],"category_scores_gemma":[0.0001290342,0.0001484593,0.00009387457,0.00008228764,0.0001063061,0.00001201128,0.00009167576,0.0001172812,0.00001846319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006754113,"about_ca_system_score_gemma":0.0000378586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006802756,"about_ca_topic_score_gemma":0.000005690635,"domain_scores_codex":[0.9989991,0.0000639029,0.0001854639,0.0003089524,0.0001269132,0.0003156927],"domain_scores_gemma":[0.9994228,0.00002075684,0.00007079639,0.0003904715,0.00005421952,0.00004091186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000984575,0.0000765962,0.001478151,0.000008541777,0.00005687218,0.000009960816,0.0001922042,0.000006929974,0.9940893,0.0003243928,0.000563101,0.003095494],"study_design_scores_gemma":[0.0008172642,0.0004123249,0.02042955,0.00001929715,0.0000632489,0.00002832583,0.0003543562,0.00001959925,0.9511039,0.001102848,0.02531226,0.0003369979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945198,0.001284035,0.00003618339,0.001168379,0.00009153539,0.0002311528,0.0000223204,0.00002375256,0.002622892],"genre_scores_gemma":[0.9972619,0.0007107413,0.0002292016,0.0009935872,0.0003474391,0.0000192978,0.00008976137,0.00002029929,0.0003278167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04298537,"threshold_uncertainty_score":0.6053994,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2623847043","doi":"10.1161/atvbaha.117.309575","title":"NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice—Brief Report","year":2017,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":347,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Innovation Cluster (Canada)","funders":"","keywords":"Inflammasome; Interleukin; Lipopolysaccharide; Cell adhesion molecule; Inflammation; In vivo; Lesion; Secretion; Medicine; Pathology; Immunology; Biology; Cytokine; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02584423629051996,"gpt":0.2776240289265715,"spread":0.2517797926360515,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006071915,0.000356736,0.0004249349,0.00009564499,0.0006031396,0.0001372522,0.0002964572,0.0003704384,0.00002315594],"category_scores_gemma":[0.0001064889,0.0003373928,0.0001532105,0.00006181651,0.0003551384,0.00003330936,0.0003696209,0.0001509303,0.00001598602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003727466,"about_ca_system_score_gemma":0.00006898713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002266204,"about_ca_topic_score_gemma":0.000231655,"domain_scores_codex":[0.9977486,0.0001332769,0.000610674,0.0008199068,0.0001446436,0.0005429444],"domain_scores_gemma":[0.9986732,0.00000826043,0.0003466369,0.0007963785,0.00007636978,0.00009914395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000008716102,0.0001373584,0.04004817,0.00002008427,0.0000813125,4.25668e-7,0.0001722629,0.000002168478,0.9576704,0.00005401371,0.0001999028,0.001605204],"study_design_scores_gemma":[0.001411357,0.0002673108,0.6974674,0.0001049203,0.00002314093,0.000003052687,0.0001283845,0.0000101278,0.2818852,0.00003064007,0.01821567,0.0004527094],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980579,0.0003024745,0.0001975846,0.0004870432,0.0002004251,0.0004734534,0.00001256568,0.00001968498,0.0002488911],"genre_scores_gemma":[0.9965574,0.002210199,0.0003261619,0.0001999626,0.00007898071,0.000156489,0.000390927,0.00003913448,0.00004074628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6757851,"threshold_uncertainty_score":0.9999078,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016741118","doi":"10.1681/asn.2010080798","title":"The Inflammasomes in Kidney Disease","year":2011,"lang":"en","type":"review","venue":"Journal of the American Society of Nephrology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":346,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Inflammasome; Innate immune system; Proinflammatory cytokine; Inflammation; Immunology; Chemokine; Kidney disease; Immune system; Pattern recognition receptor; Medicine; Secretion; Biology; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01519106243617516,"gpt":0.2805700657883698,"spread":0.2653790033521946,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005147544,0.0002517972,0.0009556196,0.00004067778,0.00009147925,0.000009247598,0.001129792,0.0001517536,0.000007165278],"category_scores_gemma":[0.0001668115,0.0001337075,0.00184255,0.0002378227,0.001135529,0.000004416539,0.0002987117,0.0004819965,0.000002346229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002817628,"about_ca_system_score_gemma":0.0008888009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002097994,"about_ca_topic_score_gemma":0.000007968049,"domain_scores_codex":[0.9981991,0.0003918433,0.0008157963,0.0001601052,0.0001381659,0.0002950066],"domain_scores_gemma":[0.9968958,0.00007190539,0.002268322,0.0005570685,0.0001167378,0.00009020176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005243543,0.0001685832,0.0006429561,0.001586954,0.002282883,0.000006967215,0.0003058163,0.000007177191,0.001993304,0.00008660716,0.1514212,0.8409732],"study_design_scores_gemma":[0.0002445537,0.0002293668,0.0008768897,0.000453376,0.0002848349,0.00003876339,0.0001368517,7.210279e-7,0.00002400363,0.00008390235,0.9974928,0.0001339522],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004487277,0.9942111,0.0000082282,0.0007970991,0.0002024805,0.0001983354,0.00001272291,0.000001281583,0.00008151153],"genre_scores_gemma":[0.0002530382,0.9972174,0.00009569847,0.001855884,0.0002732853,0.00001007338,0.000008151887,0.00002953175,0.0002569734],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8460716,"threshold_uncertainty_score":0.5452434,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1953948364","doi":"10.1016/j.immuni.2015.08.013","title":"The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity","year":2015,"lang":"en","type":"article","venue":"Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":342,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; Genentech","keywords":"Colorectal cancer; Inflammasome; Biology; Cancer research; Natural killer cell; Immunology; Cancer; Cytotoxicity; Biochemistry; Genetics; Inflammation; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.01015282025203651,"gpt":0.2443813523014139,"spread":0.2342285320493774,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009311213,0.0001952119,0.0001479545,0.00002437101,0.0002920032,0.00008311813,0.0005589008,0.00007271407,0.000008158816],"category_scores_gemma":[0.0003594977,0.0001200659,0.00008343822,0.0001679568,0.0001749315,0.00002301521,0.000211034,0.0004355387,0.000008268875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003446517,"about_ca_system_score_gemma":0.000152076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001722692,"about_ca_topic_score_gemma":0.0007913775,"domain_scores_codex":[0.9983382,0.0006851539,0.0002022703,0.0001934087,0.0002021182,0.0003788453],"domain_scores_gemma":[0.999293,0.0001201223,0.0001214482,0.0003069704,0.0001175047,0.00004090289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006336465,0.0004452247,0.008735115,0.00006432624,0.0001412436,0.0000187892,0.004743783,0.00003933013,0.965739,0.00004258316,0.01276235,0.006634622],"study_design_scores_gemma":[0.001568063,0.0003458217,0.02895832,0.00001503216,0.00004325475,0.00002101376,0.002380144,0.0003463359,0.9480645,0.0001162164,0.01774688,0.0003944154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919193,0.006003607,0.000007522603,0.0004635396,0.0003415545,0.0003511616,0.00001074483,0.00000972622,0.0008928166],"genre_scores_gemma":[0.9987798,0.0004557182,0.00001448006,0.0001202185,0.00006098889,0.000109262,0.00006539004,0.00001832554,0.0003758321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0202232,"threshold_uncertainty_score":0.4896146,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1664996601","doi":"10.4049/jimmunol.1003597","title":"Caspase-1–Processed Cytokines IL-1β and IL-18 Promote IL-17 Production by γδ and CD4 T Cells That Mediate Autoimmunity","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":341,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trinity College","funders":"Irish Research Council; Science Foundation Ireland; Health Research Board","keywords":"Experimental autoimmune encephalomyelitis; Inflammasome; Immunology; Caspase 1; Interleukin 12; Autoimmunity; Interleukin 17; Interleukin; T cell; Biology; Cytokine; Cytotoxic T cell; Inflammation; Immune system; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.01373252813189039,"gpt":0.2150011025369827,"spread":0.2012685744050923,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006571696,0.0002079755,0.0002694047,0.00007369694,0.0002045965,0.00002104157,0.0003080604,0.0001943057,0.00003074196],"category_scores_gemma":[0.0001056265,0.0001450785,0.00006008336,0.00007801956,0.0004655551,0.00003316131,0.0001622728,0.000331633,0.000003510667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001015396,"about_ca_system_score_gemma":0.00007640407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006141426,"about_ca_topic_score_gemma":0.00001367353,"domain_scores_codex":[0.9988945,0.0002038226,0.0003495245,0.000170525,0.0001027875,0.0002788368],"domain_scores_gemma":[0.9989871,0.00001680328,0.000428762,0.0003260848,0.0002003403,0.0000409385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006434972,0.00008011994,0.0002222619,0.00002332115,0.0002281222,0.000004616982,0.00127141,0.000001660051,0.9918761,0.000003725852,0.00165084,0.003994376],"study_design_scores_gemma":[0.000900281,0.001021178,0.006093837,0.00002542026,0.0001048441,0.000525581,0.001109978,0.000003906051,0.9732348,0.0002323476,0.01656039,0.0001873878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894049,0.00922569,0.00004803613,0.0004955422,0.0003781411,0.0001641948,0.0000150615,0.000007625224,0.0002608635],"genre_scores_gemma":[0.9859439,0.01317819,0.0001177039,0.0001265841,0.00009072613,0.0000045006,0.00001799326,0.0000234035,0.0004969885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01864119,"threshold_uncertainty_score":0.591613,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2795137969","doi":"10.1161/circulationaha.117.032636","title":"Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis","year":2018,"lang":"en","type":"article","venue":"Circulation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":325,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Universiteit van Amsterdam; Rijksuniversiteit Groningen; York University; Universitair Medisch Centrum Groningen; National Center for Research Resources; University of Ottawa","keywords":"Medicine; Inflammasome; Efflux; Cholesterol; Cell biology; Inflammation; Immunology; Internal medicine; Biochemistry; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.009581525615327987,"gpt":0.2190161140785476,"spread":0.2094345884632196,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009276511,0.0001137607,0.00007946961,0.00004017341,0.0001314944,0.0000346549,0.00007471364,0.0001268231,0.00002041425],"category_scores_gemma":[0.00003605886,0.0001189081,0.00003763901,0.00006919396,0.00007995489,0.00001482538,0.00004549787,0.000033714,0.00001941803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008996459,"about_ca_system_score_gemma":0.00002169283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008855151,"about_ca_topic_score_gemma":0.00000753022,"domain_scores_codex":[0.999336,0.00003787879,0.0001484705,0.0002420623,0.00008184944,0.0001537125],"domain_scores_gemma":[0.9995348,0.000005933633,0.00006612142,0.0002426944,0.0001143956,0.00003601339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001489632,0.00001305981,0.1432983,0.000009532531,0.00002622363,3.877107e-8,0.0001893299,0.0000309459,0.8525523,0.00007944452,0.00009559837,0.003690399],"study_design_scores_gemma":[0.0003837673,0.00004359435,0.5632051,0.000008554885,0.000009652788,0.000002796369,0.00004429114,0.000163556,0.4310794,0.0000493465,0.004887011,0.000122924],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974577,0.0000869061,0.001540072,0.00006698303,0.00008510442,0.0001573801,0.0000031032,0.00001807539,0.000584621],"genre_scores_gemma":[0.9991727,0.00004075364,0.0000567184,0.0001976262,0.0003014873,0.00002116231,0.000156241,0.00002018704,0.00003310754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4214729,"threshold_uncertainty_score":0.4848932,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2023710365","doi":"10.1074/jbc.m708182200","title":"The Caspase-1 Digestome Identifies the Glycolysis Pathway as a Target during Infection and Septic Shock","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":324,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Pyroptosis; Glycolysis; Biology; Glyceraldehyde 3-phosphate dehydrogenase; Caspase 1; Cell biology; Caspase; Inflammasome; Heat shock protein; Biochemistry; Dehydrogenase; Enzyme; Apoptosis","retraction":null,"screen_n_in":null,"score":{"opus":0.005880344113618233,"gpt":0.2266939575244735,"spread":0.2208136134108553,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000604626,0.0001235348,0.0001299634,0.00001309026,0.0002966101,0.00005720518,0.0001775362,0.0001701559,0.00002409544],"category_scores_gemma":[0.0003731419,0.00006214889,0.0001606184,0.00007472177,0.0002076402,0.000006583184,0.0001030009,0.0002294636,0.000002662533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001659705,"about_ca_system_score_gemma":0.00003449267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005338426,"about_ca_topic_score_gemma":0.000005026251,"domain_scores_codex":[0.999164,0.0000371209,0.0003271249,0.0001302169,0.0001170269,0.000224507],"domain_scores_gemma":[0.999382,0.00005986196,0.000229963,0.0001628015,0.0001063562,0.00005905653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002186246,0.00002547908,0.007579613,0.00001110788,0.00008235034,0.0000192517,0.00003863947,0.000009958912,0.9912632,0.000003859453,0.00009572158,0.0006522713],"study_design_scores_gemma":[0.0003299259,0.0001596167,0.03203117,0.0000112609,0.00001725542,0.0004330073,0.0004331078,0.00000168876,0.9539664,0.0001586884,0.01235041,0.0001075076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958476,0.003008818,0.00004761175,0.0002040348,0.0000967271,0.00005193215,0.00000158132,0.000004320534,0.0007373948],"genre_scores_gemma":[0.9975119,0.001495435,0.00001452753,0.00007304158,0.0002900658,0.000002803044,0.000006315322,0.000006612067,0.0005993306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03729676,"threshold_uncertainty_score":0.2534358,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}