{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":873,"total_is_capped":false,"direct_labels_cover":2,"predictions_cover":873,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"32c08eb5d9d0","filters":{"topic":"Neuroblastoma Research and Treatments"}},"results":[{"id":"W2132546867","doi":"10.1038/ng.2529","title":"The genetic landscape of high-risk neuroblastoma","year":2013,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":1219,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; National Human Genome Research Institute; National Institute on Minority Health and Health Disparities; Canadian Institutes of Health Research; National Institutes of Health","keywords":"ATRX; Biology; Neuroblastoma RAS viral oncogene homolog; PTPN11; Neuroblastoma; Germline mutation; Germline; Exome sequencing; CHEK2; Genetics; Somatic cell; Cancer research; Mutation; Exome; Gene; KRAS","authors":[{"name":"Trevor J. Pugh","is_ca":false},{"name":"Olena Morozova","is_ca":true},{"name":"Edward F. Attiyeh","is_ca":false},{"name":"Shahab Asgharzadeh","is_ca":false},{"name":"Jun S. Wei","is_ca":false},{"name":"Daniel Auclair","is_ca":false},{"name":"Scott L. Carter","is_ca":false},{"name":"Kristian Cibulskis","is_ca":false},{"name":"Megan Hanna","is_ca":false},{"name":"Adam Kieżun","is_ca":false},{"name":"Jaegil Kim","is_ca":false},{"name":"Michael S. Lawrence","is_ca":false},{"name":"Lee Lichenstein","is_ca":false},{"name":"Aaron McKenna","is_ca":false},{"name":"Chandra Sekhar Pedamallu","is_ca":false},{"name":"Alex H. Ramos","is_ca":false},{"name":"Erica Shefler","is_ca":false},{"name":"Andrey Sivachenko","is_ca":false},{"name":"Carrie Sougnez","is_ca":false},{"name":"Chip Stewart","is_ca":false},{"name":"Adrian Ally","is_ca":true},{"name":"İnanç Birol","is_ca":true},{"name":"Readman Chiu","is_ca":true},{"name":"Richard Corbett","is_ca":true},{"name":"Martin Hirst","is_ca":true},{"name":"Shaun D. Jackman","is_ca":true},{"name":"Baljit Kamoh","is_ca":true},{"name":"Alireza Hadj Khodabakshi","is_ca":true},{"name":"Martin Krzywinski","is_ca":true},{"name":"Allan Lo","is_ca":true},{"name":"Richard A. Moore","is_ca":true},{"name":"Karen Mungall","is_ca":true},{"name":"Jenny Q. Qian","is_ca":true},{"name":"Angela Tam","is_ca":true},{"name":"Nina Thiessen","is_ca":true},{"name":"Yongjun Zhao","is_ca":true},{"name":"Kristina A. Cole","is_ca":false},{"name":"Maura Diamond","is_ca":false},{"name":"Sharon J. Diskin","is_ca":false},{"name":"Yaël P. Mossé","is_ca":false},{"name":"Andrew Wood","is_ca":false},{"name":"Lingyun Ji","is_ca":false},{"name":"Richard Sposto","is_ca":false},{"name":"Thomas Badgett","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"Yvonne Moyer","is_ca":false},{"name":"Julie M. Gastier‐Foster","is_ca":false},{"name":"Malcolm A. Smith","is_ca":false},{"name":"Jaime M. Guidry Auvil","is_ca":false},{"name":"Daniela S. Gerhard","is_ca":false},{"name":"Michael D. Hogarty","is_ca":false},{"name":"Steven J.M. Jones","is_ca":true},{"name":"Eric S. Lander","is_ca":false},{"name":"Stacey Gabriel","is_ca":false},{"name":"Gad Getz","is_ca":false},{"name":"Robert C. Seeger","is_ca":false},{"name":"Javed Khan","is_ca":false},{"name":"Marco A. Marra","is_ca":true},{"name":"Matthew Meyerson","is_ca":false},{"name":"John M. Maris","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005299584076040456,"gpt":0.2492781974386105,"spread":0.2439786133625701,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002881937,0.0002309509,0.0002771819,0.001012964,0.0004973285,0.0007023364,0.0004430694,0.0006459038,0.00324228],"category_scores_gemma":[0.002171354,0.0001594577,0.0001861276,0.001103213,0.0004338297,0.0004484081,0.0005535993,0.0005451415,0.0002553283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000432258,"about_ca_system_score_gemma":0.0004590744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003782628,"about_ca_topic_score_gemma":0.003994302,"domain_scores_codex":[0.9995204,0.0001475805,0.00003265743,0.00009762342,0.0001219948,0.00007977036],"domain_scores_gemma":[0.9993912,0.0002260837,0.000177943,0.00003150589,0.00006878533,0.0001044664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007824718,0.00009545189,0.8957937,0.0001047935,0.0002543767,0.01046131,0.0007791095,0.001452011,0.03050644,0.007062417,0.002508861,0.05019905],"study_design_scores_gemma":[0.00003413516,0.0001753307,0.9441224,0.0001487467,0.0003466511,0.02608582,0.001678085,0.001650979,0.004285083,0.01487067,0.006554089,0.00004794243],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871071,0.003664813,0.0005087141,0.002602452,0.00003054405,0.000008902688,0.0003880947,0.00001881386,0.005670501],"genre_scores_gemma":[0.9976615,0.001354927,0.0002749702,0.0001229764,0.00004307994,0.000002936468,0.0001521507,0.000009833462,0.0003777337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003782628,"threshold_uncertainty_score":0.0108465,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029883816","doi":"10.1172/jci8829","title":"Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":1175,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; University of Toronto; Hospital for Sick Children","funders":"National Institutes of Health; National Cancer Institute; Cancer Care Ontario","keywords":"Medicine; Vinblastine; Pharmacology; Angiogenesis; Chemotherapy; In vivo; Cancer research; Toxicity; Combination therapy; Oncology; Internal medicine; Biology","authors":[{"name":"Giannoula Klement","is_ca":false},{"name":"Sylvain Baruchel","is_ca":true},{"name":"Janusz Rak","is_ca":true},{"name":"Shan Man","is_ca":true},{"name":"Katherine Clark","is_ca":true},{"name":"Daniel J. Hicklin","is_ca":false},{"name":"Peter Böhlen","is_ca":false},{"name":"Robert S. Kerbel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04590777157183174,"gpt":0.3935550668225939,"spread":0.3476472952507622,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001719335,0.0002936695,0.0004911225,0.0002322932,0.0001411699,0.0003246175,0.0003219039,0.0002100451,0.001248461],"category_scores_gemma":[0.0001311613,0.0001098123,0.0001436941,0.0001896275,0.0002441432,0.0001621107,0.0001727107,0.0007214008,0.0002722257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004544198,"about_ca_system_score_gemma":0.0004103982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001021639,"about_ca_topic_score_gemma":0.003849312,"domain_scores_codex":[0.9998087,0.00003217837,0.00001535754,0.00004001678,0.00005299061,0.00005064745],"domain_scores_gemma":[0.9998695,0.00002706467,0.00002639557,0.00001926945,0.000008795053,0.00004905131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006306881,0.0006747306,0.0004962378,0.00006183792,0.0000157483,0.00004472129,0.00002307644,0.0001819246,0.9890705,0.0001465426,0.0003649205,0.008289021],"study_design_scores_gemma":[0.0002561912,0.00508869,0.007522353,0.00001063911,0.00003780151,0.0003167313,0.00002221662,0.001673321,0.9782914,0.00003855622,0.006734498,0.000007712812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919668,0.00269878,0.002082917,0.0000873816,0.0000708471,0.00009854361,0.0003144554,0.0001655942,0.002514696],"genre_scores_gemma":[0.9933311,0.0007497476,0.002748604,0.00004211366,0.00002555473,0.00008341344,0.0005119226,0.00002079232,0.002486659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001248461,"threshold_uncertainty_score":0.004176497,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2286322195","doi":"10.1016/j.cell.2016.01.015","title":"New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs","year":2016,"lang":"en","type":"article","venue":"Cell","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":1009,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; McGill University and Génome Québec Innovation Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"School of Medicine, University of Missouri; National Center for Advancing Translational Sciences; Heidelberger Zentrum für Personalisierte Onkologie Deutsches Krebsforschungszentrum In Der Helmholtz-Gemeinschaft; National Institutes of Health; Hospital for Sick Children; Deutsche Krebshilfe; Bundesministerium für Bildung und Forschung; Deutsche Kinderkrebsstiftung; Institut National Du Cancer; Cancer Research UK; Brain Tumour Charity; Rosetrees Trust; National Cancer Institute; Making Headway Foundation; Deutsches Krebsforschungszentrum; St. Jude Children's Research Hospital","keywords":"Biology; Neuroepithelial cell; Central nervous system; Neuroblastoma; Pathology; Brain tumor; Neuroscience; Stem cell; Medicine; Neural stem cell; Genetics; Cell culture","authors":[{"name":"Dominik Sturm","is_ca":false},{"name":"Brent A. Orr","is_ca":false},{"name":"Umut H. Toprak","is_ca":false},{"name":"Volker Hovestadt","is_ca":false},{"name":"David Jones","is_ca":false},{"name":"David Capper","is_ca":false},{"name":"Martin Sill","is_ca":false},{"name":"Ivo Buchhalter","is_ca":false},{"name":"Paul A. Northcott","is_ca":false},{"name":"Irina Leis","is_ca":false},{"name":"Marina Ryzhova","is_ca":false},{"name":"Christian Koelsche","is_ca":false},{"name":"Elke Pfaff","is_ca":false},{"name":"Sariah J. Allen","is_ca":false},{"name":"Gnanaprakash Balasubramanian","is_ca":false},{"name":"Barbara C. Worst","is_ca":false},{"name":"Kristian W. Pajtler","is_ca":false},{"name":"Sebastian Brabetz","is_ca":false},{"name":"Pascal D. Johann","is_ca":false},{"name":"Felix Sahm","is_ca":false},{"name":"Jüri Reimand","is_ca":true},{"name":"Alan Mackay","is_ca":false},{"name":"Diana Carvalho","is_ca":false},{"name":"Marc Remke","is_ca":true},{"name":"Joanna J. Phillips","is_ca":false},{"name":"Arie Perry","is_ca":false},{"name":"Cynthia Cowdrey","is_ca":false},{"name":"Rachid Drissi","is_ca":false},{"name":"Maryam Fouladi","is_ca":false},{"name":"Felice Giangaspero","is_ca":false},{"name":"Maria Łastowska","is_ca":false},{"name":"Wiesława Grajkowska","is_ca":false},{"name":"Wolfram Scheurlen","is_ca":false},{"name":"Torsten Pietsch","is_ca":false},{"name":"Christian Hagel","is_ca":false},{"name":"Johannes Gojo","is_ca":false},{"name":"Daniela Lötsch","is_ca":false},{"name":"Walter Berger","is_ca":false},{"name":"Irene Slavc","is_ca":false},{"name":"Christine Haberler","is_ca":false},{"name":"Anne Jouvet","is_ca":false},{"name":"Stefan Holm","is_ca":false},{"name":"Silvia Höfer","is_ca":false},{"name":"Marco Prinz","is_ca":false},{"name":"Catherine Keohane","is_ca":false},{"name":"Iris Fried","is_ca":false},{"name":"Christian Mawrin","is_ca":false},{"name":"David Scheie","is_ca":false},{"name":"Bret C. Mobley","is_ca":false},{"name":"Matthew Schniederjan","is_ca":false},{"name":"Mariarita Santi","is_ca":false},{"name":"Anna Maria Buccoliero","is_ca":false},{"name":"Sonika Dahiya","is_ca":false},{"name":"Christof M. Kramm","is_ca":false},{"name":"André O. von Bueren","is_ca":false},{"name":"Katja von Hoff","is_ca":false},{"name":"Stefan Rutkowski","is_ca":false},{"name":"Christel Herold‐Mende","is_ca":false},{"name":"Michael C. Frühwald","is_ca":false},{"name":"Till Milde","is_ca":false},{"name":"Martin Hasselblatt","is_ca":false},{"name":"Pieter Wesseling","is_ca":false},{"name":"Jochen Rößler","is_ca":false},{"name":"Ulrich Schüller","is_ca":false},{"name":"Martin Ebinger","is_ca":false},{"name":"Jens Schittenhelm","is_ca":false},{"name":"Stephan Frank","is_ca":false},{"name":"Rainer Grobholz","is_ca":false},{"name":"István Vajtai","is_ca":false},{"name":"Volkmar Hans","is_ca":false},{"name":"Reinhard Schneppenheim","is_ca":false},{"name":"Karel Zitterbart","is_ca":false},{"name":"V. Peter Collins","is_ca":false},{"name":"Eleonora Aronica","is_ca":false},{"name":"Pascale Varlet","is_ca":false},{"name":"Stéphanie Puget","is_ca":false},{"name":"Christelle Dufour","is_ca":false},{"name":"Jacques Grill","is_ca":false},{"name":"Dominique Figarella‐Branger","is_ca":false},{"name":"Marietta Wolter","is_ca":false},{"name":"Martin U. Schuhmann","is_ca":false},{"name":"Tarek Shalaby","is_ca":false},{"name":"Michael A. Grotzer","is_ca":false},{"name":"Timothy Van Meter","is_ca":false},{"name":"Camelia‐Maria Monoranu","is_ca":false},{"name":"Jörg Felsberg","is_ca":false},{"name":"Guido Reifenberger","is_ca":false},{"name":"Matija Snuderl","is_ca":false},{"name":"Lynn Ann Forrester","is_ca":false},{"name":"Jan Köster","is_ca":false},{"name":"Rogier Versteeg","is_ca":false},{"name":"Richard Volckmann","is_ca":false},{"name":"Peter van Sluis","is_ca":false},{"name":"Stephan Wolf","is_ca":false},{"name":"Tom Mikkelsen","is_ca":false},{"name":"Amar Gajjar","is_ca":false},{"name":"Kenneth Aldape","is_ca":false},{"name":"Andrew S. Moore","is_ca":false},{"name":"Michael D. Taylor","is_ca":true},{"name":"Chris Jones","is_ca":false},{"name":"Nada Jabado","is_ca":true},{"name":"Matthias A. Karajannis","is_ca":false},{"name":"Roland Eils","is_ca":false},{"name":"Matthias Schlesner","is_ca":false},{"name":"Peter Lichter","is_ca":false},{"name":"Andreas von Deimling","is_ca":false},{"name":"Stefan M. Pfister","is_ca":false},{"name":"David W. Ellison","is_ca":false},{"name":"Andrey Korshunov","is_ca":false},{"name":"Marcel Kool","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01894804525880438,"gpt":0.2740198097670117,"spread":0.2550717645082073,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007743318,0.0005707619,0.0007780679,0.001681771,0.000458628,0.0016907,0.0006998019,0.0005825307,0.001724728],"category_scores_gemma":[0.001068107,0.0001336878,0.0004575863,0.001204161,0.0009184495,0.001467775,0.001135743,0.001115157,0.0007522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009162412,"about_ca_system_score_gemma":0.001129988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001708448,"about_ca_topic_score_gemma":0.004550328,"domain_scores_codex":[0.999612,0.00005555958,0.00005241306,0.00005777629,0.0001529876,0.00006919383],"domain_scores_gemma":[0.9994552,0.0001021158,0.000155938,0.0000479396,0.0001431907,0.00009561527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001235824,0.0001808947,0.262387,0.001714079,0.0002768168,0.01908674,0.001077113,0.002695206,0.1401813,0.07675201,0.01644603,0.4779669],"study_design_scores_gemma":[0.0002110434,0.0008170261,0.3172972,0.001505769,0.0009219351,0.127881,0.005407469,0.01137345,0.06342471,0.1041147,0.3668919,0.0001536806],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.756096,0.1147428,0.03899622,0.01522049,0.001796532,0.0003641257,0.002135876,0.0007428398,0.06990503],"genre_scores_gemma":[0.9121028,0.04548129,0.02977176,0.00192326,0.00114659,0.0001289207,0.003211926,0.00009937501,0.006134141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001724728,"threshold_uncertainty_score":0.006647825,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2060275730","doi":"10.1038/nature07397","title":"Activating mutations in ALK provide a therapeutic target in neuroblastoma","year":2008,"lang":"en","type":"article","venue":"Nature","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":892,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pediatric Oncology Group","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute","keywords":"Neuroblastoma; Anaplastic lymphoma kinase; Cancer research; Biology; Gene knockdown; Molecular biology; Small hairpin RNA; Mutation; Tyrosine kinase; Cell culture; Gene; Signal transduction; Cell biology; Genetics; Medicine; Pathology","authors":[{"name":"Rani E. George","is_ca":true},{"name":"Takaomi Sanda","is_ca":true},{"name":"Megan Hanna","is_ca":false},{"name":"Stefan Fröhling","is_ca":false},{"name":"William Luther","is_ca":true},{"name":"Jianming Zhang","is_ca":false},{"name":"Yebin Ahn","is_ca":true},{"name":"Wenjun Zhou","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"Patrick McGrady","is_ca":false},{"name":"Liquan Xue","is_ca":false},{"name":"Sergey Zozulya","is_ca":false},{"name":"V. Gregor","is_ca":false},{"name":"Thomas R. Webb","is_ca":false},{"name":"Nathanael S. Gray","is_ca":false},{"name":"D. Gary Gilliland","is_ca":false},{"name":"Lisa Diller","is_ca":true},{"name":"Heidi Greulich","is_ca":false},{"name":"Stephan W. Morris","is_ca":false},{"name":"Matthew Meyerson","is_ca":false},{"name":"A. Thomas Look","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01921542182137839,"gpt":0.3121136169284821,"spread":0.2928981951071037,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002761045,0.000237903,0.0003518558,0.0004076265,0.0003760555,0.0007461047,0.0002813608,0.0006018609,0.004588241],"category_scores_gemma":[0.0002760023,0.0001883223,0.0002168354,0.0003302752,0.0003659965,0.0008309329,0.0004318303,0.00101192,0.001217126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004922342,"about_ca_system_score_gemma":0.0005015231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004014954,"about_ca_topic_score_gemma":0.001202023,"domain_scores_codex":[0.9999106,0.00001476043,0.000007597242,0.000009259657,0.00003385043,0.00002384004],"domain_scores_gemma":[0.9999373,0.00001534135,0.000009836991,0.000005855987,0.0000147547,0.000016873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00233543,0.0003887152,0.006485566,0.0008191774,0.00009769609,0.002546925,0.0002883011,0.003490422,0.4576048,0.04908098,0.04148232,0.4353796],"study_design_scores_gemma":[0.0009231537,0.002543636,0.01336157,0.0002519897,0.0005354549,0.01498735,0.0008818696,0.003854244,0.3117636,0.03587852,0.6149504,0.0000681743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5738459,0.2121646,0.01398654,0.05682081,0.003644121,0.0001746447,0.0009374066,0.0007492701,0.1376767],"genre_scores_gemma":[0.8811078,0.07719825,0.006271728,0.003506807,0.001119426,0.00006296824,0.0004032268,0.00008439504,0.0302454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004588241,"threshold_uncertainty_score":0.01534921,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124343455","doi":"10.3332/ecancer.2014.463","title":"ecancermedicalscience","year":2016,"lang":"en","type":"article","venue":"ecancermedicalscience","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":679,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Clinical trial; Repurposing; Cancer; Clinical Practice; Oncology; Intensive care medicine; Internal medicine; Family medicine","authors":[{"name":"Gauthier Bouche","is_ca":false},{"name":"Nicolás André","is_ca":false},{"name":"Shripad Banavali","is_ca":false},{"name":"Frank Berthold","is_ca":false},{"name":"Alfredo Berruti","is_ca":false},{"name":"Guido Bocci","is_ca":false},{"name":"Giovanni Brandi","is_ca":false},{"name":"Ugo Cavallaro","is_ca":false},{"name":"Saverio Cinieri","is_ca":false},{"name":"Marco Colleoni","is_ca":false},{"name":"Giuseppe Curigliano","is_ca":false},{"name":"Teresa Di Desidero","is_ca":false},{"name":"Alexandru Eniu","is_ca":false},{"name":"Nicola Fazio","is_ca":false},{"name":"Robert S. Kerbel","is_ca":true},{"name":"Lisa Hutchinson","is_ca":false},{"name":"Urszula Ledzewicz","is_ca":false},{"name":"Elisabetta Munzone","is_ca":false},{"name":"Eddy Pasquier","is_ca":false},{"name":"O. Graciela Scharovsky","is_ca":false},{"name":"Yuval Shaked","is_ca":false},{"name":"Jaroslav Štěrba","is_ca":false},{"name":"Martín Villalba","is_ca":false},{"name":"Francesco Bertolini","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01494786441112387,"gpt":0.3209219483150048,"spread":0.3059740839038809,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0008135856,0.001163531,0.000629114,0.00197724,0.0008085677,0.003871194,0.001149724,0.003523221,0.7517061],"category_scores_gemma":[0.003225946,0.0004330299,0.0007120174,0.001142937,0.0006593808,0.001832272,0.002233596,0.003256471,0.6264804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001182458,"about_ca_system_score_gemma":0.00183815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001661046,"about_ca_topic_score_gemma":0.002631495,"domain_scores_codex":[0.9991042,0.0001203949,0.00005254139,0.0002367615,0.0003503236,0.0001358402],"domain_scores_gemma":[0.9984066,0.0002842562,0.0001057931,0.00017875,0.0003769283,0.0006476695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007050647,0.00005049232,0.0004134599,0.0004752989,0.00001179759,0.0003384482,0.00005564971,0.0000725414,0.0007194633,0.004699127,0.6806328,0.3124603],"study_design_scores_gemma":[0.00001300796,0.00001242379,0.0002105805,0.0001148997,0.000002184599,0.0005021507,0.00002384987,0.00002940679,0.00009623339,0.0004920217,0.9984995,0.000003774256],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001496202,0.02339511,0.001953671,0.01412066,0.01576355,0.0002234293,0.002873135,0.002287738,0.9378865],"genre_scores_gemma":[0.008716085,0.01665419,0.002102483,0.006833701,0.003531186,0.0001559511,0.0034741,0.0006547215,0.9578776],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.2482939,"threshold_uncertainty_score":0.354161,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101042741","doi":"10.1200/jco.2005.05.571","title":"Evidence for an Age Cutoff Greater Than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":587,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute","keywords":"Medicine; Cutoff; Neuroblastoma; Stage (stratigraphy); Internal medicine; Pediatric oncology; Risk stratification; Cancer; Oncology; Pediatrics","authors":[{"name":"Wendy B. London","is_ca":false},{"name":"R P Castleberry","is_ca":true},{"name":"Katherine K. Matthay","is_ca":true},{"name":"A. Thomas Look","is_ca":true},{"name":"Robert C. Seeger","is_ca":true},{"name":"Hiroyuki Shimada","is_ca":true},{"name":"Paul S. Thorner","is_ca":true},{"name":"G M Brodeur","is_ca":true},{"name":"John M. Maris","is_ca":true},{"name":"C. Patrick Reynolds","is_ca":true},{"name":"Susan L. Cohn","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2710879266510203,"gpt":0.512960278752268,"spread":0.2418723521012477,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01340954,0.0004024501,0.0005851698,0.001376285,0.0003974696,0.0009491931,0.0007923164,0.0009847836,0.001517284],"category_scores_gemma":[0.04420716,0.0002024317,0.001041223,0.001729602,0.000758223,0.0006788439,0.0007062932,0.0007362689,0.0002652751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005431385,"about_ca_system_score_gemma":0.001034001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002593303,"about_ca_topic_score_gemma":0.003265993,"domain_scores_codex":[0.9940229,0.003508326,0.0005990273,0.0004656694,0.001120147,0.0002839263],"domain_scores_gemma":[0.9271843,0.04992415,0.01464279,0.003152814,0.002955339,0.002140693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009904692,0.00001520983,0.9902163,0.00005587709,0.0001293697,0.00004691012,0.00005445168,0.0001952543,0.00009654934,0.00007486057,0.0002926159,0.007832156],"study_design_scores_gemma":[0.000146084,0.0004860449,0.9951372,0.0001693573,0.0004434363,0.0003909876,0.0001718236,0.001434856,0.0003306114,0.000350181,0.0009268742,0.00001268843],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867144,0.009262374,0.001309678,0.00110844,0.00009672973,0.00003793189,0.0003516655,0.00002746332,0.001091354],"genre_scores_gemma":[0.9975375,0.0006581213,0.001185557,0.0001799249,0.0000793637,0.00002115409,0.0002689221,0.00001063553,0.00005891777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01340954,"threshold_uncertainty_score":0.07091725,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2213548494","doi":"10.1038/ng.3333","title":"Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations","year":2015,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":555,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"National Human Genome Research Institute; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services; Universiteit van Amsterdam; Fondation Nelia et Amadeo Barletta; Agence Nationale de la Recherche; National Institute on Minority Health and Health Disparities; Annenberg Foundation","keywords":"Biology; Neuroblastoma; MAPK/ERK pathway; Cancer research; Somatic cell; Phenotype; Mutation; In vivo; Germline mutation; Genotype; Genetics; Cell culture; Signal transduction; Gene","authors":[{"name":"Thomas F. Eleveld","is_ca":false},{"name":"Derek A. Oldridge","is_ca":false},{"name":"Virginie Bernard","is_ca":false},{"name":"Jan Köster","is_ca":false},{"name":"Léo Colmet‐Daage","is_ca":false},{"name":"Sharon J. Diskin","is_ca":false},{"name":"Linda Schild","is_ca":false},{"name":"Nadia Bessoltane Bentahar","is_ca":false},{"name":"Angela Bellini","is_ca":false},{"name":"Mathieu Chicard","is_ca":false},{"name":"Eve Lapouble","is_ca":false},{"name":"Valérie Combaret","is_ca":false},{"name":"Patricia Legoix-Né","is_ca":false},{"name":"Jean Michon","is_ca":false},{"name":"Trevor J. Pugh","is_ca":true},{"name":"Lori S. Hart","is_ca":false},{"name":"JulieAnn Rader","is_ca":false},{"name":"Edward F. Attiyeh","is_ca":false},{"name":"Jun S. Wei","is_ca":false},{"name":"Shile Zhang","is_ca":false},{"name":"Arlene Naranjo","is_ca":false},{"name":"Julie M. Gastier‐Foster","is_ca":false},{"name":"Michael D. Hogarty","is_ca":false},{"name":"Shahab Asgharzadeh","is_ca":false},{"name":"Malcolm A. Smith","is_ca":false},{"name":"Jaime M. Guidry Auvil","is_ca":false},{"name":"Thomas B.K. Watkins","is_ca":false},{"name":"Danny A. Zwijnenburg","is_ca":false},{"name":"Marli E. Ebus","is_ca":false},{"name":"Peter van Sluis","is_ca":false},{"name":"Anne Hakkert","is_ca":false},{"name":"Esther van Wezel","is_ca":false},{"name":"C. Ellen van der Schoot","is_ca":false},{"name":"Ellen M. Westerhout","is_ca":false},{"name":"Johannes H. Schulte","is_ca":false},{"name":"Godelieve A.M. Tytgat","is_ca":false},{"name":"M. Emmy M. Dolman","is_ca":false},{"name":"Isabelle Janoueix‐Lerosey","is_ca":false},{"name":"Daniela S. Gerhard","is_ca":false},{"name":"Huib N. Caron","is_ca":false},{"name":"Olivier Delattre","is_ca":false},{"name":"Javed Khan","is_ca":false},{"name":"Rogier Versteeg","is_ca":false},{"name":"Gudrun Schleiermacher","is_ca":false},{"name":"Jan J. Molenaar","is_ca":false},{"name":"John M. Maris","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02693391353906878,"gpt":0.3070803402388448,"spread":0.280146426699776,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002458458,0.0004158149,0.0004037311,0.001016405,0.000352508,0.0006550064,0.0003714683,0.0006710546,0.004005128],"category_scores_gemma":[0.0007627996,0.0002130313,0.0003877701,0.0009849886,0.0003232848,0.0004226863,0.0004803091,0.0003541707,0.001546562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003243462,"about_ca_system_score_gemma":0.0002156638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001510455,"about_ca_topic_score_gemma":0.002130066,"domain_scores_codex":[0.9997107,0.00002498878,0.00003640752,0.00006027367,0.0001143167,0.0000533596],"domain_scores_gemma":[0.9995549,0.00008763284,0.0001345508,0.00007124296,0.00008823244,0.00006351739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001017015,0.00007349391,0.3112758,0.0002190736,0.0002072346,0.09648342,0.000631798,0.0006119019,0.5285891,0.001141821,0.002994678,0.05675463],"study_design_scores_gemma":[0.00004159268,0.0002557125,0.5385693,0.0000541495,0.0003009113,0.355637,0.001120762,0.0009926198,0.08670666,0.001594638,0.01468066,0.00004597664],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844723,0.002337236,0.001154448,0.0003064699,0.0000552694,0.00002110242,0.001104044,0.0002115311,0.01033761],"genre_scores_gemma":[0.9963636,0.0006097293,0.0008916463,0.00005564707,0.00002384051,0.000007086581,0.0005704126,0.0000374952,0.001440691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004005128,"threshold_uncertainty_score":0.01339853,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3184057816","doi":"10.1200/jco.21.00278","title":"Revised Neuroblastoma Risk Classification System: A Report From the Children's Oncology Group","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":474,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute","keywords":"Neuroblastoma; Medicine; Cog; Oncology; Histology; Internal medicine; Stage (stratigraphy); Disease; Pathology; Biology","authors":[{"name":"Meredith S. Irwin","is_ca":true},{"name":"Arlene Naranjo","is_ca":false},{"name":"Fan F. Zhang","is_ca":false},{"name":"Susan L. Cohn","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"Julie M. Gastier‐Foster","is_ca":false},{"name":"Nilsa C. Ramirez","is_ca":false},{"name":"Ruthann Pfau","is_ca":false},{"name":"Shalini C. Reshmi","is_ca":false},{"name":"Elizabeth M. Wagner","is_ca":false},{"name":"Jed G. Nuchtern","is_ca":false},{"name":"Shahab Asgharzadeh","is_ca":false},{"name":"Hiroyuki Shimada","is_ca":false},{"name":"John M. Maris","is_ca":false},{"name":"Rochelle Bagatell","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Michael D. Hogarty","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1226237096784024,"gpt":0.4633957730206369,"spread":0.3407720633422346,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003526584,0.0008433497,0.0005560684,0.003171053,0.0003578238,0.0007523291,0.001004646,0.0004303979,0.0009493483],"category_scores_gemma":[0.007949094,0.0002145407,0.0007081443,0.003091983,0.0002210763,0.0005133993,0.0009161631,0.00113264,0.0007557801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002568848,"about_ca_system_score_gemma":0.004050441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04847639,"about_ca_topic_score_gemma":0.03273985,"domain_scores_codex":[0.9981735,0.0002526324,0.0003022371,0.0002364052,0.0008837167,0.0001514628],"domain_scores_gemma":[0.9945326,0.0004916346,0.0008088253,0.0002023918,0.0035167,0.0004479318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001788356,0.00004694063,0.7256246,0.0002477191,0.0002022289,0.0002350682,0.0001725347,0.002073917,0.000647775,0.0009146124,0.1505443,0.1191114],"study_design_scores_gemma":[0.00009637976,0.00009616437,0.8608873,0.0005211522,0.0002958164,0.001641655,0.0002438363,0.003331418,0.001293963,0.0004904707,0.131032,0.00006983348],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5614562,0.04227555,0.03936211,0.01994554,0.004471292,0.004390132,0.2641441,0.001641779,0.06231323],"genre_scores_gemma":[0.5469932,0.02867763,0.0793175,0.002964146,0.00087725,0.005413378,0.3255788,0.0005146828,0.009663395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04847639,"threshold_uncertainty_score":0.09638846,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W145418528","doi":"10.1016/j.pcl.2014.09.015","title":"Neuroblastoma","year":2014,"lang":"en","type":"review","venue":"Pediatric Clinics of North America","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":396,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Hospital for Sick Children; SickKids Foundation","funders":"","keywords":"Medicine; Neuroblastoma; Radiation therapy; Chemotherapy; Pediatric cancer; Oncology; Clinical trial; Internal medicine; Cancer; Surgery","authors":[{"name":"Meredith S. Irwin","is_ca":true},{"name":"Julie R. Park","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04734969217714067,"gpt":0.3865380495766112,"spread":0.3391883573994705,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001861297,0.0005019935,0.0005239994,0.001685417,0.0003625197,0.0007333988,0.0004344547,0.0005958842,0.02050526],"category_scores_gemma":[0.0007709916,0.0001587414,0.0002620144,0.001229162,0.0002736971,0.0007472923,0.000786777,0.000935556,0.007841538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004335447,"about_ca_system_score_gemma":0.001245037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002175767,"about_ca_topic_score_gemma":0.006166051,"domain_scores_codex":[0.9998864,0.00001460761,0.00001414744,0.0000232389,0.00004079465,0.00002079079],"domain_scores_gemma":[0.9998443,0.00003958518,0.00002876252,0.000009997863,0.00004602518,0.00003129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000451787,0.00002042026,0.0007669988,0.003373682,0.00002628789,0.001150578,0.0000536841,0.000188007,0.001182133,0.003036743,0.1145087,0.8756475],"study_design_scores_gemma":[0.00001685697,0.0000226151,0.0009665182,0.002515773,0.00005937865,0.009193195,0.00006736675,0.00005201997,0.0006113324,0.0009025063,0.9855835,0.000008993557],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001129626,0.9408419,0.0009290203,0.001273238,0.001794385,0.00004086742,0.0003368948,0.0001544518,0.05349978],"genre_scores_gemma":[0.01339356,0.950708,0.001777137,0.002361477,0.0009560562,0.00003802579,0.0009781005,0.00002458888,0.02976299],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02050526,"threshold_uncertainty_score":0.0685969,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1995294036","doi":"10.1056/nejmoa012387","title":"Screening of Infants and Mortality Due to Neuroblastoma","year":2002,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":356,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Montreal Children's Hospital; Centre Hospitalier Universitaire de Sherbrooke; Canadian Medical Association; Hospital for Sick Children; SickKids Foundation; Centre Hospitalier Universitaire Sainte-Justine; Statistics Canada","funders":"National Cancer Institute","keywords":"Neuroblastoma; Medicine; Confidence interval; Cohort; Incidence (geometry); Standardized mortality ratio; Pediatrics; Rate ratio; Mortality rate; Demography; Cohort study; Surgery; Internal medicine","authors":[{"name":"William G. Woods","is_ca":false},{"name":"Ru‐Nie Gao","is_ca":true},{"name":"Jonathan J. Shuster","is_ca":false},{"name":"Leslie L. Robison","is_ca":false},{"name":"Mark L. Bernstein","is_ca":true},{"name":"Sheila Weitzman","is_ca":true},{"name":"Greta R. Bunin","is_ca":false},{"name":"Isra Levy","is_ca":true},{"name":"Josée Brossard","is_ca":true},{"name":"Geoffrey Dougherty","is_ca":true},{"name":"Mendel Tuchman","is_ca":false},{"name":"Bernard Lemieux","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04688130828961368,"gpt":0.319993884786906,"spread":0.2731125764972923,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005632301,0.0001807718,0.000163733,0.0005427431,0.0003074888,0.0002658262,0.0002628674,0.0002642497,0.0008460247],"category_scores_gemma":[0.003835678,0.00008810215,0.000182738,0.0003656606,0.0001897022,0.0001230846,0.0002087274,0.0003531373,0.00009373463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001454246,"about_ca_system_score_gemma":0.001026258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1605764,"about_ca_topic_score_gemma":0.1380803,"domain_scores_codex":[0.999553,0.0001182463,0.00002083143,0.0000409064,0.0001437724,0.0001231783],"domain_scores_gemma":[0.9986739,0.0002278495,0.00044622,0.00003091942,0.0003983446,0.0002228356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003041222,0.000007569565,0.9968933,0.000009416901,0.000008653714,0.000118861,0.00005219629,0.00004302198,0.0000666584,0.00001307508,0.0002681639,0.002488601],"study_design_scores_gemma":[0.000001638667,0.00005555143,0.9987966,0.00002543652,0.00001024053,0.0004236757,0.0000616239,0.0001355044,0.00009473989,0.00001149008,0.0003815981,0.00000184789],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959066,0.00170191,0.00009886397,0.0002430631,0.00001239342,0.00001105988,0.0004276422,0.00001328672,0.001585186],"genre_scores_gemma":[0.9989094,0.000474611,0.0000888482,0.00003908555,0.000005249521,0.000004745556,0.0002734654,0.000001320577,0.0002032358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1605764,"threshold_uncertainty_score":0.3192835,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4206379059","doi":"10.1038/s41591-021-01625-x","title":"Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication","year":2022,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":255,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Deutsche Krebshilfe; Wellcome Trust; Alex's Lemonade Stand Foundation for Childhood Cancer; University of Southern California; National Cancer Institute; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"CD47; Blockade; Calreticulin; Cancer research; Monoclonal antibody; Neuroblastoma; Medicine; Macrophage; Immunotherapy; Tumor microenvironment; Immunology; Cancer; Antibody; Biology; Receptor; Immune system; Internal medicine; Cell culture; Cell biology; Tumor cells","authors":[{"name":"Johanna Theruvath","is_ca":false},{"name":"Marie Ménard","is_ca":false},{"name":"Benjamin Smith","is_ca":false},{"name":"Miles H. Linde","is_ca":false},{"name":"Garry L. Coles","is_ca":false},{"name":"Guillermo Nicolás Dalton","is_ca":false},{"name":"Wei Wu","is_ca":false},{"name":"Louise Kiru","is_ca":false},{"name":"Alberto Delaidelli","is_ca":true},{"name":"Elena Sotillo","is_ca":false},{"name":"John L. Silberstein","is_ca":false},{"name":"Anna C. Geraghty","is_ca":false},{"name":"Allison Banuelos","is_ca":false},{"name":"Molly Radosevich","is_ca":false},{"name":"Shaurya Dhingra","is_ca":false},{"name":"Sabine Heitzeneder","is_ca":false},{"name":"Aidan M. Tousley","is_ca":false},{"name":"John Lattin","is_ca":false},{"name":"Peng Xu","is_ca":false},{"name":"Jing Huang","is_ca":false},{"name":"Nicole Nasholm","is_ca":false},{"name":"Andy He","is_ca":false},{"name":"Tracy C. Kuo","is_ca":false},{"name":"Emma Sangalang","is_ca":false},{"name":"Jaume Pons","is_ca":false},{"name":"Amira Barkal","is_ca":false},{"name":"Rachel Brewer","is_ca":false},{"name":"Kristopher D. Marjon","is_ca":false},{"name":"José G. Vilches-Moure","is_ca":false},{"name":"Payton L. Marshall","is_ca":false},{"name":"Ricardo A. Fernandes","is_ca":false},{"name":"Michelle Monje","is_ca":false},{"name":"Jennifer R. Cochran","is_ca":false},{"name":"Poul H. Sorensen","is_ca":true},{"name":"Heike E. Daldrup‐Link","is_ca":false},{"name":"Irving L. Weissman","is_ca":false},{"name":"Julien Sage","is_ca":false},{"name":"Ravindra Majeti","is_ca":false},{"name":"Carolyn R. Bertozzi","is_ca":false},{"name":"William A. Weiss","is_ca":false},{"name":"Crystal L. Mackall","is_ca":false},{"name":"Robbie G. Majzner","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006035995999071824,"gpt":0.2871763778405188,"spread":0.281140381841447,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002078682,0.0005245651,0.0005268551,0.0003706469,0.0002250547,0.0005184613,0.0003093347,0.0004934088,0.003638404],"category_scores_gemma":[0.0001097139,0.000168007,0.0004820224,0.0002780904,0.0002790768,0.0003367598,0.0003261406,0.001288081,0.0008253154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004579146,"about_ca_system_score_gemma":0.0007162225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009711666,"about_ca_topic_score_gemma":0.002984948,"domain_scores_codex":[0.9997895,0.00003326872,0.000009845682,0.00002168441,0.00003675484,0.0001089695],"domain_scores_gemma":[0.9999346,0.0000118242,0.00000923774,0.000009410474,0.000004834465,0.00003018044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005277753,0.002293854,0.0007641747,0.0002606612,0.0001231515,0.0002430156,0.00005378582,0.00118059,0.9613183,0.001367696,0.004255022,0.02286207],"study_design_scores_gemma":[0.0011825,0.007962035,0.006474144,0.00002360504,0.00009566107,0.0007073689,0.0001154052,0.00284004,0.9596043,0.000362089,0.02061037,0.00002255556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815709,0.002885431,0.001538553,0.0007424389,0.0003762609,0.0001589037,0.001107623,0.0003576183,0.0112623],"genre_scores_gemma":[0.9915397,0.001356978,0.001192464,0.0001878244,0.00005774345,0.0001180813,0.0008591561,0.00003195887,0.004656016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003638404,"threshold_uncertainty_score":0.01217175,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2122250312","doi":"10.1200/jco.2011.37.9990","title":"Outcome After Surgery Alone or With Restricted Use of Chemotherapy for Patients With Low-Risk Neuroblastoma: Results of Children's Oncology Group Study P9641","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":239,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital","funders":"National Cancer Institute; National Institutes of Health; Children’s Oncology Group","keywords":"Medicine; Asymptomatic; Chemotherapy; Neuroblastoma; Stage (stratigraphy); Surgery; Disease; Internal medicine; Oncology","authors":[{"name":"Douglas Strother","is_ca":true},{"name":"Wendy B. London","is_ca":true},{"name":"Mary Lou Schmidt","is_ca":true},{"name":"Garrett M. Brodeur","is_ca":true},{"name":"Hiroyuki Shimada","is_ca":true},{"name":"Paul S. Thorner","is_ca":true},{"name":"Margaret H. Collins","is_ca":true},{"name":"Edward P. Tagge","is_ca":true},{"name":"Stanton Adkins","is_ca":true},{"name":"C. Patrick Reynolds","is_ca":true},{"name":"Kevin Murray","is_ca":true},{"name":"Robert S. Lavey","is_ca":true},{"name":"Katherine K. Matthay","is_ca":true},{"name":"Robert P. Castleberry","is_ca":true},{"name":"John M. Maris","is_ca":true},{"name":"Susan L. Cohn","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08496636381527489,"gpt":0.41899630753716,"spread":0.3340299437218851,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001188978,0.0003579071,0.0005336908,0.0003890659,0.0002973217,0.0005199547,0.0003083704,0.0005381105,0.0008204905],"category_scores_gemma":[0.002332795,0.0001353774,0.0009481122,0.000593696,0.0002849477,0.0004857372,0.0004250953,0.0006189591,0.0001539122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007153858,"about_ca_system_score_gemma":0.0006412272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002682988,"about_ca_topic_score_gemma":0.003795211,"domain_scores_codex":[0.9993376,0.0002515753,0.0000566124,0.0001245557,0.0001095112,0.0001202175],"domain_scores_gemma":[0.9975917,0.0006415111,0.0007867481,0.0001747216,0.0001767264,0.0006285874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01200983,0.00037076,0.9768739,0.00005725999,0.0004961809,0.0003551553,0.0001134839,0.0008627481,0.0005012758,0.00004152228,0.0007727995,0.007545053],"study_design_scores_gemma":[0.0006603163,0.005094047,0.9925563,0.00002229377,0.0002291583,0.0003623146,0.0000870361,0.0002662548,0.0001689738,0.00003595863,0.0005036118,0.00001384052],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985418,0.000384666,0.0000319925,0.00005986758,0.000008026902,0.00001665907,0.0005688423,0.000002336695,0.00038585],"genre_scores_gemma":[0.9974679,0.0002057473,0.00003964717,0.00006733427,0.00001746068,0.00002530416,0.002027751,0.000002969978,0.0001458784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002682988,"threshold_uncertainty_score":0.006287992,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1969402650","doi":"10.1158/0008-5472.can-06-2117","title":"Targeting Liposomal Chemotherapy via Both Tumor Cell–Specific and Tumor Vasculature–Specific Ligands Potentiates Therapeutic Efficacy","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":231,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Neuroblastoma; Doxorubicin; Cancer research; Medicine; Angiogenesis; Cancer; Pharmacology; Chemotherapy; Biology; Internal medicine; Cell culture","authors":[{"name":"Fabio Pastorino","is_ca":false},{"name":"Chiara Brignole","is_ca":false},{"name":"Daniela Di Paolo","is_ca":false},{"name":"Bice Nico","is_ca":false},{"name":"Annalisa Pezzolo","is_ca":false},{"name":"Danilo Marimpietri","is_ca":false},{"name":"Gabriella Pagnan","is_ca":false},{"name":"Federica Piccardi","is_ca":false},{"name":"Michele Cilli","is_ca":false},{"name":"Renato Longhi","is_ca":false},{"name":"Doménico Ribatti","is_ca":false},{"name":"Angelo Corti","is_ca":false},{"name":"Theresa M. Allen","is_ca":true},{"name":"Mirco Ponzoni","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02772456210869785,"gpt":0.3278074989992909,"spread":0.3000829368905931,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001402185,0.0002784331,0.0002587565,0.0001812635,0.00005791146,0.0002382194,0.0001020499,0.00018178,0.0008746735],"category_scores_gemma":[0.0001031681,0.00007941526,0.0001052229,0.0001126648,0.000157061,0.0002257161,0.0002065877,0.0003720488,0.0002709329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002615137,"about_ca_system_score_gemma":0.0001494988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001860039,"about_ca_topic_score_gemma":0.0003521471,"domain_scores_codex":[0.9999183,0.00001877796,0.000006938808,0.00001633309,0.00001744014,0.00002218245],"domain_scores_gemma":[0.9999495,0.00001285028,0.00001345396,0.000005652432,0.000007664044,0.00001095601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001417392,0.00007231403,0.0001085061,0.00006034905,0.000006069532,0.00003226981,0.00001790116,0.000327339,0.9913242,0.0002042345,0.00009566193,0.007609561],"study_design_scores_gemma":[0.00005565872,0.001092046,0.00131484,0.00001026349,0.00003340009,0.0001594174,0.00001000173,0.001883928,0.9896641,0.00005652072,0.005713578,0.000006211883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857423,0.004936414,0.005578012,0.0001531355,0.0000478932,0.0000970978,0.0001220349,0.0001674445,0.003155613],"genre_scores_gemma":[0.9933866,0.00219734,0.002511056,0.00005701188,0.00002399593,0.00005674662,0.0001422768,0.00001741987,0.001607616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008746735,"threshold_uncertainty_score":0.002926052,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2725857922","doi":"10.1158/1078-0432.ccr-17-0652","title":"Retinoblastoma and Neuroblastoma Predisposition and Surveillance","year":2017,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":230,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; American Association for Cancer Research","keywords":"Retinoblastoma; Neuroblastoma; Medicine; Genetic predisposition; Pathology; Biology; Cancer research; Genetics; Gene; Disease; Cell culture","authors":[{"name":"Junne Kamihara","is_ca":false},{"name":"Franck Bourdeaut","is_ca":false},{"name":"William D. Foulkes","is_ca":true},{"name":"Jan J. Molenaar","is_ca":false},{"name":"Yaël P. Mossé","is_ca":false},{"name":"Akira Nakagawara","is_ca":false},{"name":"Andreu Parareda","is_ca":false},{"name":"Sarah Scollon","is_ca":false},{"name":"Kami Wolfe Schneider","is_ca":false},{"name":"Alison H. Skalet","is_ca":false},{"name":"Lisa J. States","is_ca":false},{"name":"Michael F. Walsh","is_ca":false},{"name":"Lisa Diller","is_ca":false},{"name":"Garrett M. Brodeur","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.5637842129581868,"gpt":0.6469697183172912,"spread":0.0831855053591044,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007359585,0.0004655913,0.0008449306,0.002525849,0.0002668661,0.0007561165,0.0006929002,0.0008550651,0.003818961],"category_scores_gemma":[0.001233796,0.0001805687,0.0004688766,0.001992053,0.0003052607,0.0007440746,0.0005341985,0.001285467,0.001582234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009074817,"about_ca_system_score_gemma":0.001631303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003125184,"about_ca_topic_score_gemma":0.00483503,"domain_scores_codex":[0.9997461,0.00005605842,0.00003918468,0.00003673254,0.00009927816,0.00002257917],"domain_scores_gemma":[0.9995459,0.0001894928,0.00007063217,0.000009961507,0.000147145,0.00003679691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000434641,0.00003555131,0.0004697133,0.01480945,0.00008123362,0.0002607543,0.00005877256,0.0002084596,0.0004028288,0.003414813,0.05741184,0.9228032],"study_design_scores_gemma":[0.0000154085,0.00004862221,0.001647174,0.01382955,0.0001566253,0.00232409,0.00007111146,0.00005582619,0.0002329934,0.001731048,0.9798728,0.00001481001],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005757045,0.9983504,0.00003471994,0.0003967478,0.0001154885,0.000002629449,0.00001428731,0.000003535956,0.001024737],"genre_scores_gemma":[0.0007069347,0.9984554,0.0000804056,0.0002335973,0.0001162367,0.000005227446,0.00002938178,8.231127e-7,0.0003719215],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003818961,"threshold_uncertainty_score":0.01277572,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2754294524","doi":"10.1016/j.ccell.2017.08.003","title":"Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma","year":2017,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":228,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Cancer Agency; SickKids Foundation; Hospital for Sick Children","funders":"National Institutes of Health; National Institute of General Medical Sciences; Alex's Lemonade Stand Foundation for Childhood Cancer; National Cancer Institute; Damon Runyon Cancer Research Foundation","keywords":"Neuroblastoma; Identification (biology); Cancer research; Biology; Computational biology; Cell culture; Genetics","authors":[{"name":"Kristopher R. Bosse","is_ca":false},{"name":"Pichai Raman","is_ca":false},{"name":"Zhongyu Zhu","is_ca":false},{"name":"Maria Lane","is_ca":false},{"name":"Daniel Martínez","is_ca":false},{"name":"Sabine Heitzeneder","is_ca":false},{"name":"Komal S. Rathi","is_ca":false},{"name":"Nathan M. Kendsersky","is_ca":false},{"name":"Michael P. Randall","is_ca":false},{"name":"Laura Donovan","is_ca":true},{"name":"A. Sorana Morrissy","is_ca":true},{"name":"Robyn T. Sussman","is_ca":false},{"name":"Doncho V. Zhelev","is_ca":false},{"name":"Yang Feng","is_ca":false},{"name":"Yanping Wang","is_ca":false},{"name":"Jennifer Hwang","is_ca":false},{"name":"Gonzalo López","is_ca":false},{"name":"Jo Lynne Harenza","is_ca":false},{"name":"Jun S. Wei","is_ca":false},{"name":"Bruce Pawel","is_ca":false},{"name":"Tricia Bhatti","is_ca":false},{"name":"Mariarita Santi","is_ca":false},{"name":"Arupa Ganguly","is_ca":false},{"name":"Javed Khan","is_ca":false},{"name":"Marco A. Marra","is_ca":true},{"name":"Michael D. Taylor","is_ca":true},{"name":"Dimiter S. Dimitrov","is_ca":false},{"name":"Crystal L. Mackall","is_ca":false},{"name":"John M. Maris","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01165331880939907,"gpt":0.3126967280895578,"spread":0.3010434092801587,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001946711,0.0002280972,0.0003181499,0.0003965939,0.0002834555,0.0005920184,0.0002527758,0.0004827828,0.001432002],"category_scores_gemma":[0.0001893552,0.000129123,0.0002439526,0.0003819122,0.0002201695,0.0002926613,0.0002857407,0.0005751501,0.0002877698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006222892,"about_ca_system_score_gemma":0.0004549245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00109715,"about_ca_topic_score_gemma":0.001247727,"domain_scores_codex":[0.9999186,0.00001179482,0.000004551794,0.00001393464,0.00002754723,0.00002360295],"domain_scores_gemma":[0.9999528,0.000008203227,0.000006905636,0.000005222201,0.00001156913,0.00001534381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007471799,0.0001868331,0.008908605,0.0001890246,0.00004613048,0.001355697,0.00007743141,0.0006291919,0.9615805,0.001564773,0.001056507,0.02365822],"study_design_scores_gemma":[0.0002064318,0.001535934,0.05087609,0.00006138645,0.0001915114,0.008440207,0.0003516982,0.008967998,0.8929727,0.001141082,0.0352264,0.00002853682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853913,0.007159014,0.002124165,0.0006870134,0.00005267381,0.0001050761,0.0003605738,0.00004414218,0.004076091],"genre_scores_gemma":[0.9920189,0.003214717,0.002207319,0.0001169157,0.00002431324,0.00004900327,0.0006873914,0.000008392166,0.001672961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001432002,"threshold_uncertainty_score":0.004790545,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2126177906","doi":"10.1093/jnci/djp230","title":"Long-term Outcomes in Survivors of Neuroblastoma: A Report From the Childhood Cancer Survivor Study","year":2009,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University of Alberta; Université de Montréal","funders":"National Cancer Institute","keywords":"Medicine; Cumulative incidence; Neuroblastoma; Confidence interval; Cohort; Incidence (geometry); Pediatrics; Sibling; Poisson regression; Cancer; Cohort study; Internal medicine; Population; Environmental health","authors":[{"name":"Caroline Laverdière","is_ca":true},{"name":"Qi Liu","is_ca":true},{"name":"Yutaka Yasui","is_ca":true},{"name":"Paul C. Nathan","is_ca":true},{"name":"James G. Gurney","is_ca":false},{"name":"Marilyn Stovall","is_ca":false},{"name":"Lisa Diller","is_ca":false},{"name":"Nai‐Kong V. Cheung","is_ca":false},{"name":"Suzanne L. Wolden","is_ca":false},{"name":"Leslie L. Robison","is_ca":false},{"name":"Charles A. Sklar","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05643377881008291,"gpt":0.3854253000697375,"spread":0.3289915212596546,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009426016,0.0001632491,0.0002603003,0.0005946868,0.0002832545,0.000337815,0.0002111587,0.0002118993,0.0006629791],"category_scores_gemma":[0.002779942,0.0001161917,0.0002893172,0.0009770581,0.0001610601,0.0002381173,0.0004096858,0.0003096794,0.0001091956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002706455,"about_ca_system_score_gemma":0.0005199044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02422648,"about_ca_topic_score_gemma":0.02880492,"domain_scores_codex":[0.999694,0.00007916665,0.0000465712,0.00004180204,0.00008950879,0.00004898731],"domain_scores_gemma":[0.9983606,0.0002441037,0.0007226187,0.00007718911,0.0003232714,0.0002722348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00002059684,0.000006169597,0.9985299,0.00001325245,0.00003852826,0.00006011631,0.0001097775,0.00001631344,0.00002133442,0.00000876054,0.000310318,0.0008648781],"study_design_scores_gemma":[0.000003200021,0.00001921723,0.9992707,0.00001334048,0.00003113713,0.0001198368,0.0001767509,0.0000178554,0.00001528812,0.000006959058,0.0003235911,0.000002127558],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939857,0.00132341,0.00007710994,0.0001990138,0.00001348018,0.00001505377,0.003794763,0.000004676591,0.000586732],"genre_scores_gemma":[0.9952077,0.001062552,0.0000663163,0.00004408279,0.00001339545,0.00002665037,0.003394957,0.000002148294,0.0001821031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02422648,"threshold_uncertainty_score":0.04817092,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2168659791","doi":"10.1158/0008-5472.can-07-0718","title":"Neuroblastoma Cells Isolated from Bone Marrow Metastases Contain a Naturally Enriched Tumor-Initiating Cell","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":180,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health","keywords":"Neuroblastoma; Bone marrow; Neural crest; Pathology; Cancer research; Primary tumor; Minimal residual disease; Biology; Cancer; Medicine; Metastasis; Internal medicine; Cell culture; Cell biology; Embryo","authors":[{"name":"Loen M. Hansford","is_ca":false},{"name":"Amy E. McKee","is_ca":false},{"name":"Libo Zhang","is_ca":false},{"name":"Rani E. George","is_ca":false},{"name":"J. Ted Gerstle","is_ca":false},{"name":"Paul S. Thorner","is_ca":false},{"name":"Kristen M. Smith","is_ca":false},{"name":"A. Thomas Look","is_ca":false},{"name":"Herman Yeger","is_ca":false},{"name":"Freda D. Miller","is_ca":true},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Carol J. Thiele","is_ca":false},{"name":"David R. Kaplan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04306065587262296,"gpt":0.3702739728556713,"spread":0.3272133169830483,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001435179,0.0001571415,0.0002639249,0.0001859323,0.0001724503,0.0002184401,0.0001041749,0.0001362642,0.001292802],"category_scores_gemma":[0.0002587563,0.00007524368,0.0001060698,0.0001563933,0.0001274879,0.0001019403,0.0001973882,0.0003237401,0.0006373188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000110861,"about_ca_system_score_gemma":0.0002213193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001403401,"about_ca_topic_score_gemma":0.003504558,"domain_scores_codex":[0.9998802,0.00001305856,0.00001340393,0.00002056313,0.00005750629,0.00001534009],"domain_scores_gemma":[0.9998304,0.00005972058,0.00001434839,0.00002838385,0.00003295065,0.0000342466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008440865,0.00002762402,0.004482822,0.00003944475,0.000009402731,0.000163428,0.00007432405,0.00005758696,0.9911959,0.0002286728,0.00009896437,0.003537377],"study_design_scores_gemma":[0.00004768277,0.0006849442,0.06526289,0.00002620226,0.00005304413,0.004718788,0.000155307,0.001520871,0.9121311,0.0003298427,0.01505163,0.00001761161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829845,0.002444225,0.01008574,0.00006208349,0.0000259807,0.0001317205,0.0009878241,0.00007218087,0.003205688],"genre_scores_gemma":[0.9790703,0.001115885,0.01323555,0.00004219144,0.00001166188,0.00007429835,0.003693781,0.00002601301,0.002730333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001403401,"threshold_uncertainty_score":0.004324853,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2143660636","doi":"10.1111/j.1365-3016.2008.00983.x","title":"The epidemiology of neuroblastoma: a review","year":2008,"lang":"en","type":"review","venue":"Paediatric and Perinatal Epidemiology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":171,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Environmental Health Sciences","keywords":"Medicine; Epidemiology; Neuroblastoma; Disease; Cohort study; Pregnancy; Population; Environmental health; Pediatrics; Internal medicine","authors":[{"name":"Julia E. Heck","is_ca":false},{"name":"Beate Ritz","is_ca":false},{"name":"Mia Hashibe","is_ca":false},{"name":"Paolo Boffetta","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1132450901244594,"gpt":0.4206397767962182,"spread":0.3073946866717588,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009160838,0.0009347305,0.002730854,0.006003832,0.0003305413,0.001274475,0.0009354735,0.000977066,0.002814254],"category_scores_gemma":[0.002765015,0.0004877346,0.001034879,0.008335247,0.000406389,0.001464386,0.0005916354,0.0007622264,0.0006059671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001142169,"about_ca_system_score_gemma":0.003336038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00535257,"about_ca_topic_score_gemma":0.009380118,"domain_scores_codex":[0.9993055,0.0001556378,0.0002204795,0.000086712,0.0001967838,0.00003490698],"domain_scores_gemma":[0.9986081,0.0008339811,0.0002702654,0.0000186227,0.0002302132,0.00003887409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001062267,0.00005683468,0.001902104,0.2713569,0.0008023425,0.0008981693,0.0003079752,0.0003926894,0.0007416971,0.001317531,0.02115771,0.7009599],"study_design_scores_gemma":[0.00005786818,0.0002658676,0.0189766,0.2585475,0.003705245,0.009544473,0.0008771256,0.0001550873,0.0004496209,0.001786048,0.7055617,0.00007296516],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009800575,0.9995621,0.00002169143,0.00008994233,0.00005208731,0.000004843899,0.00001736266,0.000001540324,0.0001523199],"genre_scores_gemma":[0.0003383151,0.999485,0.00005982842,0.00003912333,0.00002371093,0.000003829184,0.00001186645,2.450836e-7,0.00003816106],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006003832,"threshold_uncertainty_score":0.01064283,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2961969123","doi":"10.1038/s41568-019-0169-x","title":"Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours","year":2019,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research; Princess Margaret Cancer Centre; University Health Network","funders":"World Health Organization","keywords":"Computational biology; Medicine; Cancer research; Biology; Intensive care medicine","authors":[{"name":"David Jones","is_ca":false},{"name":"Ana Banito","is_ca":false},{"name":"Thomas G. P. Grünewald","is_ca":false},{"name":"Michelle Haber","is_ca":false},{"name":"Natalie Jäger","is_ca":false},{"name":"Marcel Kool","is_ca":false},{"name":"Till Milde","is_ca":false},{"name":"Jan J. Molenaar","is_ca":false},{"name":"Arash Nabbi","is_ca":true},{"name":"Trevor J. Pugh","is_ca":true},{"name":"Gudrun Schleiermacher","is_ca":false},{"name":"Malcolm A. Smith","is_ca":false},{"name":"Frank Westermann","is_ca":false},{"name":"Stefan M. Pfister","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04916384748397009,"gpt":0.4341655619739588,"spread":0.3850017144899887,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004490784,0.0006992616,0.001111603,0.001674803,0.0002105226,0.0009252936,0.0007536752,0.0008212238,0.003772405],"category_scores_gemma":[0.0006895941,0.0002401838,0.0004469749,0.00172605,0.0005668279,0.001020364,0.0008752421,0.001780657,0.001351263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009023512,"about_ca_system_score_gemma":0.0008356598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001090452,"about_ca_topic_score_gemma":0.002655887,"domain_scores_codex":[0.9998272,0.00003169899,0.00002411742,0.00003189902,0.00005819655,0.00002700495],"domain_scores_gemma":[0.9997292,0.0001422485,0.00004756256,0.000008131378,0.00004968217,0.00002310609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001239926,0.00002967647,0.0002640372,0.01361738,0.0000904117,0.0002668575,0.00005376369,0.000543594,0.002802999,0.007386173,0.03289657,0.9419245],"study_design_scores_gemma":[0.00001548749,0.00007297262,0.0009708485,0.00433467,0.00011703,0.001879951,0.00005385613,0.00007584183,0.0006726074,0.003008523,0.9887812,0.00001700433],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009576439,0.9986873,0.00006092051,0.0003150339,0.0001304786,0.000001687603,0.00001986758,0.000004281511,0.0006846636],"genre_scores_gemma":[0.0005569716,0.998752,0.00006132171,0.0001641489,0.0001009478,0.000002656299,0.00002800047,8.648324e-7,0.0003330862],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003772405,"threshold_uncertainty_score":0.01261997,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2810818134","doi":"10.1007/s00259-018-4070-8","title":"Guidelines on nuclear medicine imaging in neuroblastoma","year":2018,"lang":"en","type":"article","venue":"European Journal of Nuclear Medicine and Molecular Imaging","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Medicine; Neuroblastoma; Nuclear medicine imaging; Medical physics; Nuclear medicine; Clinical Practice; Radiology; Family medicine","authors":[{"name":"Zvi Bar‐Sever","is_ca":false},{"name":"Lorenzo Biassoni","is_ca":false},{"name":"Barry L. Shulkin","is_ca":false},{"name":"Grace Kong","is_ca":false},{"name":"Michael S. Hofman","is_ca":false},{"name":"Egesta Lopci","is_ca":false},{"name":"Irina Manea","is_ca":false},{"name":"Jacek Koziorowski","is_ca":false},{"name":"Maria Rita Castellani","is_ca":false},{"name":"Ariane Boubaker","is_ca":false},{"name":"Bieke Lambert","is_ca":false},{"name":"Thomas Pfluger","is_ca":false},{"name":"Helen Nadel","is_ca":true},{"name":"Susan E. Sharp","is_ca":false},{"name":"Francesco Giammarile","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03276467106406806,"gpt":0.3307028953573262,"spread":0.2979382242932581,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008671041,0.001318406,0.002226841,0.004684338,0.00185981,0.002755754,0.003744117,0.01175604,0.004765139],"category_scores_gemma":[0.02636567,0.001051945,0.003361091,0.00293674,0.002659794,0.001968695,0.002827435,0.0126308,0.003689432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004156775,"about_ca_system_score_gemma":0.01106312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01621392,"about_ca_topic_score_gemma":0.02419708,"domain_scores_codex":[0.9906551,0.003261666,0.003492655,0.0003780985,0.00168584,0.0005266672],"domain_scores_gemma":[0.9742129,0.01294159,0.002963263,0.0006997511,0.007916484,0.001266021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002414204,0.0002392028,0.003128608,0.009310292,0.0002510195,0.002518189,0.0007325462,0.002267587,0.002972472,0.01887843,0.6604021,0.2990582],"study_design_scores_gemma":[0.0001360688,0.0001067918,0.005118332,0.02200204,0.0003794361,0.004937094,0.0002508572,0.0004294783,0.0009065225,0.0108034,0.9548385,0.00009164306],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.003433323,0.577486,0.02092505,0.2781799,0.01704999,0.0009201584,0.002511967,0.0009547897,0.09853886],"genre_scores_gemma":[0.04660669,0.5342453,0.110405,0.2401234,0.02272481,0.003808997,0.009471318,0.0005998343,0.03201462],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.01621392,"threshold_uncertainty_score":0.04585743,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2735902464","doi":"10.1002/cncr.30873","title":"Association of <i>MYCN</i> copy number with clinical features, tumor biology, and outcomes in neuroblastoma: A report from the Children's Oncology Group","year":2017,"lang":"en","type":"article","venue":"Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Institutes of Health; National Cancer Institute; St. Baldrick's Foundation","keywords":"Neuroblastoma; Medicine; Oncology; Internal medicine; Stage (stratigraphy); Disease; Chemotherapy; Cancer; Genetics; Biology; Cell culture","authors":[{"name":"Kevin Campbell","is_ca":false},{"name":"Julie M. Gastier‐Foster","is_ca":false},{"name":"Meegan Mann","is_ca":false},{"name":"Arlene Naranjo","is_ca":false},{"name":"Collin Van Ryn","is_ca":false},{"name":"Rochelle Bagatell","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Hiroyuki Shimada","is_ca":false},{"name":"Meaghan Granger","is_ca":false},{"name":"Michael D. Hogarty","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Steven G. DuBois","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01967968440705006,"gpt":0.3996647990397395,"spread":0.3799851146326895,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007666211,0.0002258214,0.0002400153,0.0009422743,0.0002642872,0.000351889,0.0001997872,0.0002257893,0.0005186672],"category_scores_gemma":[0.001939098,0.0001537403,0.0002393126,0.0009901054,0.000316576,0.0002049395,0.0002104418,0.0002738702,0.0001001182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004129404,"about_ca_system_score_gemma":0.0004611111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00803736,"about_ca_topic_score_gemma":0.007278758,"domain_scores_codex":[0.999668,0.0000467199,0.00004099859,0.00008026675,0.0001260766,0.00003795158],"domain_scores_gemma":[0.9984993,0.0005691178,0.0004303053,0.00008410033,0.0002951981,0.0001219845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007274813,0.000007872992,0.9965641,0.00001748241,0.00003504359,0.0002452261,0.0000535391,0.00004130963,0.0003002047,0.000005568887,0.0001982509,0.002458593],"study_design_scores_gemma":[0.000008589446,0.00008606284,0.9959436,0.00001214978,0.00007748423,0.002556705,0.00008536199,0.0000705019,0.0004446912,0.00000889075,0.0006987624,0.000007026747],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996771,0.001648973,0.0001185212,0.00008901138,0.00001009931,0.00001115472,0.0006997405,0.000007069562,0.0006443869],"genre_scores_gemma":[0.9979606,0.000987986,0.0002109994,0.00003230292,0.00002412566,0.000008855459,0.0006600338,0.000004443574,0.0001105972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00803736,"threshold_uncertainty_score":0.01598114,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2121699071","doi":"10.1158/0008-5472.can-06-3607","title":"Tumor-Targeted Enzyme/Prodrug Therapy Mediates Long-term Disease-Free Survival of Mice Bearing Disseminated Neuroblastoma","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia Hospital","funders":"National Cancer Institute; National Science Council","keywords":"Prodrug; Neuroblastoma; Progenitor cell; Carboxylesterase; Pharmacology; In vivo; Cancer research; Suicide gene; Cell culture; Genetic enhancement; Cytotoxicity; Medicine; Stem cell; Enzyme; Biology; In vitro; Biochemistry; Cell biology; Gene","authors":[{"name":"Mary K. Danks","is_ca":false},{"name":"Karina J. Yoon","is_ca":false},{"name":"Rebecca A. Bush","is_ca":false},{"name":"Joanna S. Remack","is_ca":false},{"name":"Monika Wierdl","is_ca":false},{"name":"Lyudmila Tsurkan","is_ca":false},{"name":"Seung Up Kim","is_ca":true},{"name":"Elizabeth Garcia","is_ca":false},{"name":"Marianne Z. Metz","is_ca":false},{"name":"Joseph Najbauer","is_ca":false},{"name":"Philip M. Potter","is_ca":false},{"name":"Karen S. Aboody","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05281070467650965,"gpt":0.3901860075831745,"spread":0.3373753029066648,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002588913,0.0004840543,0.0005188024,0.0003210072,0.0001974439,0.0002831174,0.0002835185,0.0003872241,0.0008691082],"category_scores_gemma":[0.0001330342,0.0001675187,0.0002576672,0.0001296684,0.0002379588,0.0002705418,0.0001550566,0.0009310064,0.0002810624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004903976,"about_ca_system_score_gemma":0.0003909656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001468979,"about_ca_topic_score_gemma":0.002751827,"domain_scores_codex":[0.9998063,0.00002503079,0.00001457789,0.00003561418,0.00004395706,0.00007449681],"domain_scores_gemma":[0.9998411,0.00002796657,0.00004426767,0.00002532207,0.00001413509,0.00004720401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003193424,0.0002513614,0.0001760456,0.00002918112,0.000009680551,0.00005202667,0.00003843413,0.0002248484,0.995418,0.000130247,0.000079647,0.003271133],"study_design_scores_gemma":[0.0001118582,0.00347679,0.003589929,0.00001438767,0.00003870553,0.0002609181,0.00002479144,0.002169873,0.9887236,0.00005319777,0.001529332,0.000006647322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966525,0.0006533591,0.001249972,0.0000602568,0.00002040302,0.00004413202,0.0003036956,0.00008787787,0.0009277352],"genre_scores_gemma":[0.9952609,0.0005421214,0.001242139,0.00003613916,0.00001072958,0.00006558189,0.000573431,0.00002391967,0.002245161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001468979,"threshold_uncertainty_score":0.003558099,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1967063990","doi":"10.1073/pnas.0904606106","title":"HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Neuroblastoma; Neural crest; Biology; Cancer research; Angiogenesis; Gene knockdown; Tumor progression; Pathology; Endocrinology; Cell biology; Cell culture; Embryo; Medicine; Cancer; Genetics","authors":[{"name":"Alexander Pietras","is_ca":false},{"name":"Loen M. Hansford","is_ca":true},{"name":"A. Johnsson","is_ca":false},{"name":"Esther Bridges","is_ca":false},{"name":"Jonas Sjölund","is_ca":false},{"name":"David Gisselsson","is_ca":false},{"name":"Matilda Rehn","is_ca":false},{"name":"Siv Beckman","is_ca":false},{"name":"Rosa Noguera","is_ca":false},{"name":"Samuel Navarro","is_ca":false},{"name":"Jörg Cammenga","is_ca":false},{"name":"Erik Fredlund","is_ca":false},{"name":"David R. Kaplan","is_ca":true},{"name":"Sven Påhlman","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05309707766879466,"gpt":0.3520599657054491,"spread":0.2989628880366544,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000935233,0.00006193545,0.0001069148,0.0001133828,0.0001573503,0.0002896727,0.00007207906,0.00007560395,0.0004266011],"category_scores_gemma":[0.0001182275,0.00007877994,0.00006448991,0.00008767205,0.0001081541,0.00007608586,0.0001055613,0.0001544417,0.0002493447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002525941,"about_ca_system_score_gemma":0.0002057016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002443333,"about_ca_topic_score_gemma":0.003192726,"domain_scores_codex":[0.9999317,0.000007268654,0.000006049026,0.00001424475,0.00002589368,0.00001483746],"domain_scores_gemma":[0.9999485,0.000004932852,0.00001061716,0.000007820482,0.00001337443,0.00001481225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005529191,0.00001060507,0.001458777,0.00001366716,0.000003619634,0.00005082093,0.00003393566,0.00008724658,0.9953808,0.0001310571,0.00008429787,0.002689964],"study_design_scores_gemma":[0.00001545351,0.0002088888,0.04754401,0.00001069799,0.00002298643,0.00070228,0.0001027864,0.001946975,0.9409253,0.0001334293,0.008379906,0.00000724259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953083,0.001225754,0.001549716,0.0000358092,0.000008317343,0.000008630806,0.0002953101,0.00002521725,0.001542962],"genre_scores_gemma":[0.9962295,0.0004791402,0.0009605628,0.00002704141,0.000003712895,0.000007821801,0.0007281243,0.000006207081,0.00155801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002443333,"threshold_uncertainty_score":0.004858196,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2571353014","doi":"10.1016/j.ccell.2016.12.002","title":"Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma","year":2017,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health; Fundação de Amparo à Pesquisa do Estado de São Paulo; Ontario Genomics Institute; Canada Foundation for Innovation; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; Eshelman Institute for Innovation, University of North Carolina at Chapel Hill; St. Baldrick's Foundation; Ministero dell’Istruzione, dell’Università e della Ricerca; AbbVie; Janssen Biotech; Innovative Medicines Initiative; Associazione Italiana per la Ricerca sul Cancro; Wellcome; Merck; Takeda Pharmaceuticals U.S.A.; Pfizer; Boehringer Ingelheim","keywords":"Epigenetics; Druggability; Chromatin; Biology; Small interfering RNA; Cancer research; Methyltransferase; Genetics; Bioinformatics; Cell biology; RNA; Gene; Methylation","authors":[{"name":"Veronica Veschi","is_ca":false},{"name":"Zhihui Liu","is_ca":false},{"name":"Ty C. Voss","is_ca":false},{"name":"Laurent Ozbun","is_ca":false},{"name":"Berkley E. Gryder","is_ca":false},{"name":"Chunhua Yan","is_ca":false},{"name":"Ying Hu","is_ca":false},{"name":"Anqi Ma","is_ca":false},{"name":"Jian Jin","is_ca":false},{"name":"Sharlyn J. Mazur","is_ca":false},{"name":"Norris Lam","is_ca":false},{"name":"Bárbara Kunzler Souza","is_ca":false},{"name":"Giuseppe Giannini","is_ca":false},{"name":"Gordon L. Hager","is_ca":false},{"name":"C.H. Arrowsmith","is_ca":true},{"name":"Javed Khan","is_ca":false},{"name":"Ettore Appella","is_ca":false},{"name":"Carol J. Thiele","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03744754336170057,"gpt":0.3529582167922486,"spread":0.3155106734305481,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001919573,0.0003233696,0.0003332295,0.0003065957,0.000234289,0.0003515147,0.0003352702,0.0004077849,0.003562337],"category_scores_gemma":[0.0001683435,0.0001620367,0.000365874,0.0001523054,0.0002143285,0.0001809434,0.0002247583,0.0006615805,0.0004778639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004169102,"about_ca_system_score_gemma":0.0002817825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006106409,"about_ca_topic_score_gemma":0.002664015,"domain_scores_codex":[0.9998521,0.00001780297,0.00001416586,0.00002726684,0.00006029203,0.0000283152],"domain_scores_gemma":[0.9999425,0.000015476,0.00001225047,0.00000858066,0.0000101854,0.00001099066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002749526,0.0001215605,0.0005473386,0.00008576951,0.00003048826,0.0001264055,0.00001514469,0.0004005805,0.9874601,0.0005010304,0.0005208615,0.009915707],"study_design_scores_gemma":[0.00006111798,0.0004823533,0.002408166,0.000007565724,0.00005736205,0.0003550484,0.00002917248,0.001271936,0.9900619,0.0001183565,0.005139837,0.000007211461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748724,0.003205233,0.007923932,0.0006477537,0.0001906553,0.0001484471,0.001519908,0.00037328,0.01111834],"genre_scores_gemma":[0.9892558,0.001477753,0.003619789,0.0001773371,0.00001199993,0.00007907172,0.0007646249,0.00003379146,0.004579756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003562337,"threshold_uncertainty_score":0.01191717,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4362522571","doi":"10.1038/s41591-023-02297-5","title":"Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results","year":2023,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Ignyta; Y-mAbs Therapeutics; Varian Medical Systems; St. Baldrick's Foundation; Pfizer; Actuate Therapeutics; Bristol-Myers Squibb; Eli Lilly and Company; Alex's Lemonade Stand Foundation for Childhood Cancer; V Foundation for Cancer Research","keywords":"Medicine; Internal medicine; Refractory (planetary science); Neuroblastoma; Chemotherapy; Cyclophosphamide; Adverse effect; Clinical trial; Gastroenterology; Oncology","authors":[{"name":"Kelly C. Goldsmith","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Kimberly Kayser","is_ca":false},{"name":"Jemily Malvar","is_ca":false},{"name":"Yueh‐Yun Chi","is_ca":false},{"name":"Susan Groshen","is_ca":false},{"name":"Judith G. Villablanca","is_ca":false},{"name":"Kateryna Krytska","is_ca":false},{"name":"Lillian M. Lai","is_ca":false},{"name":"Patricia T. Acharya","is_ca":false},{"name":"Fariba Goodarzian","is_ca":false},{"name":"Bruce Pawel","is_ca":false},{"name":"Hiroyuki Shimada","is_ca":false},{"name":"Susan Ghazarian","is_ca":false},{"name":"Lisa J. States","is_ca":false},{"name":"Lynley V. Marshall","is_ca":false},{"name":"Louis Chesler","is_ca":false},{"name":"Meaghan Granger","is_ca":false},{"name":"Ami V. Desai","is_ca":false},{"name":"Rajen Mody","is_ca":false},{"name":"Daniel A. Morgenstern","is_ca":true},{"name":"Suzanne Shusterman","is_ca":false},{"name":"Margaret E. Macy","is_ca":false},{"name":"Navin Pinto","is_ca":false},{"name":"Gudrun Schleiermacher","is_ca":false},{"name":"Kieuhoa T. Vo","is_ca":false},{"name":"Holger Thurm","is_ca":false},{"name":"Joseph Chen","is_ca":false},{"name":"Marlon Liyanage","is_ca":false},{"name":"Gerson Peltz","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false},{"name":"Esther R. Berko","is_ca":false},{"name":"John M. Maris","is_ca":false},{"name":"Araz Marachelian","is_ca":false},{"name":"Yaël P. Mossé","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03487887887345568,"gpt":0.3942430159057496,"spread":0.3593641370322939,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001441696,0.001005058,0.001463633,0.0002486335,0.0002771695,0.0007355508,0.0005660825,0.0008721448,0.00242659],"category_scores_gemma":[0.0009308632,0.0002550383,0.0009336508,0.0002408589,0.0006130852,0.0006667036,0.0002562702,0.002026514,0.0003734142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007973091,"about_ca_system_score_gemma":0.0009681511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008330175,"about_ca_topic_score_gemma":0.002673534,"domain_scores_codex":[0.9996062,0.0002247694,0.00002437329,0.00005398779,0.00003651934,0.0000542316],"domain_scores_gemma":[0.9995315,0.0001081886,0.0001124798,0.0000244729,0.00003150034,0.0001919557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7868476,0.02565572,0.007389355,0.002153538,0.00215756,0.0005771678,0.0003154418,0.004980044,0.03496205,0.0004650261,0.009550875,0.1249456],"study_design_scores_gemma":[0.664944,0.3080051,0.01294371,0.0001428889,0.0009638734,0.0007026111,0.00008013979,0.002433846,0.004726184,0.0002836261,0.00472301,0.00005104836],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897187,0.005241134,0.0003392679,0.0006082613,0.0001024228,0.001099092,0.001194897,0.00009138005,0.001604989],"genre_scores_gemma":[0.9874362,0.004271889,0.001138084,0.0006977516,0.0001425424,0.001335633,0.002625367,0.00002709931,0.002325392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00242659,"threshold_uncertainty_score":0.008117795,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2131690391","doi":"10.1158/0008-5472.can-15-0423","title":"WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; Structural Genomics Consortium; Ontario Institute for Cancer Research","funders":"Cancer Council NSW; Medical Research Council; Ministero dello Sviluppo Economico; University of New South Wales; Ontario Ministry of Economic Development and Innovation; Ontario Genomics Institute; Ontario Genomics; Genome Canada; Wellcome Trust; GlaxoSmithKline; Pfizer; Eli Lilly and Company","keywords":"Neuroblastoma; Biology; Cancer research; Promoter; Histone; Molecular biology; Carcinogenesis; RNA interference; Mdm2; Gene expression; Regulation of gene expression; Gene; Cell culture; Genetics; RNA","authors":[{"name":"Yuting Sun","is_ca":false},{"name":"Jessica L. Bell","is_ca":false},{"name":"Daniel R. Carter","is_ca":false},{"name":"Samuele Gherardi","is_ca":false},{"name":"Rebecca C. Poulos","is_ca":false},{"name":"Giorgio Milazzo","is_ca":false},{"name":"Jason W.H. Wong","is_ca":false},{"name":"Rima Al‐awar","is_ca":true},{"name":"Andrew E. Tee","is_ca":false},{"name":"Pei Y. Liu","is_ca":false},{"name":"Bing Liu","is_ca":false},{"name":"Bernard Atmadibrata","is_ca":false},{"name":"Matthew Wong","is_ca":false},{"name":"Toby N. Trahair","is_ca":false},{"name":"Quan Zhao","is_ca":false},{"name":"Jason M. Shohet","is_ca":false},{"name":"Ygal Haupt","is_ca":false},{"name":"Johannes H. Schulte","is_ca":false},{"name":"Peter J. Brown","is_ca":true},{"name":"C.H. Arrowsmith","is_ca":true},{"name":"Masoud Vedadi","is_ca":true},{"name":"Karen L. MacKenzie","is_ca":false},{"name":"Stefan Hüttelmaier","is_ca":false},{"name":"Giovanni Perini","is_ca":false},{"name":"Glenn M. Marshall","is_ca":false},{"name":"Antony W. Braithwaite","is_ca":false},{"name":"Tao Liu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1975364755830004,"gpt":0.4374035864360187,"spread":0.2398671108530183,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330709,0.0001776462,0.0001926155,0.0001891806,0.0002153969,0.0002332172,0.0001818065,0.0001805313,0.000833915],"category_scores_gemma":[0.00008203854,0.0001539591,0.0002142525,0.0001210211,0.0002001069,0.0001225771,0.0002117143,0.0003711329,0.0002812237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005872748,"about_ca_system_score_gemma":0.0003262261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00318116,"about_ca_topic_score_gemma":0.007770202,"domain_scores_codex":[0.9998272,0.00001803318,0.0000266757,0.00003479442,0.00006144641,0.00003182494],"domain_scores_gemma":[0.9999278,0.00000756535,0.00001806374,0.00001125525,0.000009614993,0.00002565755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001965292,0.000004934634,0.0001471811,0.00001390169,0.000001847141,0.00003124137,0.000008297638,0.00002252941,0.9994609,0.00006113975,0.00001654604,0.000211751],"study_design_scores_gemma":[0.000008992709,0.0001129124,0.009321206,0.000007076037,0.00001533015,0.0002239695,0.00004559138,0.0008735573,0.9870239,0.00003490895,0.002328915,0.000003611274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957253,0.000905328,0.001633422,0.00005509614,0.00001528445,0.0000170141,0.0004207172,0.00004444435,0.001183392],"genre_scores_gemma":[0.9937009,0.0004303824,0.001873351,0.00004034681,0.000002827598,0.00002427729,0.0009584702,0.00001135818,0.002957965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00318116,"threshold_uncertainty_score":0.006325305,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3015602128","doi":"10.1158/0008-5472.can-19-3068","title":"Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk Neuroblastoma","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Institute on Minority Health and Health Disparities; National Cancer Institute; National Institutes of Health; CANDU Owners Group; Cancer Prevention and Research Institute of Texas","keywords":"Neuroblastoma; ATRX; Telomere; Biology; Cancer research; Oncology; Cancer; Internal medicine; Exome sequencing; Medicine; Gene; Cell culture; Genetics; Mutation","authors":[{"name":"Balakrishna Koneru","is_ca":false},{"name":"Gonzalo López","is_ca":false},{"name":"Ahsan Farooqi","is_ca":false},{"name":"Karina L. Conkrite","is_ca":false},{"name":"Thinh H. Nguyen","is_ca":false},{"name":"Shawn J. Macha","is_ca":false},{"name":"Apexa Modi","is_ca":false},{"name":"Jo Lynne Rokita","is_ca":false},{"name":"Eduardo Urias","is_ca":false},{"name":"Ashly Hindle","is_ca":false},{"name":"Heather L. Davidson","is_ca":false},{"name":"Kristyn McCoy","is_ca":false},{"name":"Jonas Nance","is_ca":false},{"name":"Vanda Yazdani","is_ca":false},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Shengping Yang","is_ca":false},{"name":"David A. Wheeler","is_ca":false},{"name":"John M. Maris","is_ca":false},{"name":"Sharon J. Diskin","is_ca":false},{"name":"C. Patrick Reynolds","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1679903595228826,"gpt":0.4605438150124882,"spread":0.2925534554896057,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004286279,0.0001388866,0.0001767736,0.0003247407,0.0001815074,0.0003475114,0.0001638537,0.0002646683,0.001198335],"category_scores_gemma":[0.001127638,0.00006483307,0.0001452265,0.000259798,0.0001868798,0.0002510853,0.0003564022,0.0002648033,0.0001999913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002069425,"about_ca_system_score_gemma":0.0001325557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006445703,"about_ca_topic_score_gemma":0.0009869157,"domain_scores_codex":[0.9998698,0.00004082792,0.00001560382,0.00002667394,0.00002226798,0.00002477869],"domain_scores_gemma":[0.999248,0.0001981725,0.0002745646,0.00003697217,0.00006340868,0.0001788747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004510872,0.00001853629,0.9930789,0.000008104642,0.00002109993,0.0001002088,0.000046592,0.0001396275,0.003653423,0.0000264161,0.00005314543,0.002402791],"study_design_scores_gemma":[0.000006010092,0.0001334869,0.9978789,0.000005698234,0.00001795323,0.0004413256,0.0001095497,0.0003633409,0.0007894984,0.00009431881,0.0001563228,0.000003598839],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992674,0.0002058602,0.00009847174,0.00001244483,0.000001869505,0.000002960736,0.0001364529,0.000002533829,0.0002719577],"genre_scores_gemma":[0.9996284,0.00004702262,0.00005750135,0.000006896053,0.000002620364,0.000003119773,0.0001871845,9.696964e-7,0.00006629748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198335,"threshold_uncertainty_score":0.00400877,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2056621958","doi":"10.1200/jco.2013.51.2038","title":"Ototoxicity in Children With High-Risk Neuroblastoma: Prevalence, Risk Factors, and Concordance of Grading Scales—A Report From the Children's Oncology Group","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Children's Hospital of Pittsburgh; National Cancer Institute; University of Texas Health Science Center at San Antonio; University of California, Los Angeles; York University; City of Hope; Cedars-Sinai Medical Center; Children's Hospitals and Clinics of Minnesota; Seattle Children's Research Institute; Cincinnati Children's Hospital Medical Center; Tulane University; Virginia Commonwealth University; McGill University Health Centre; College of Engineering, Michigan State University; Children's National Hospital; Children's Mercy Hospital; University of South Carolina; Loma Linda University; McGill University; Dartmouth College; BC Children's Hospital; Children's Hospital Los Angeles; Louisiana State University; Children's Hospital of Philadelphia; Hospital for Sick Children; Georgetown University; West Virginia University; Kaiser Permanente; University of Illinois at Urbana-Champaign; Michigan State University; Cleveland Clinic; University of Minnesota; Bunning Food Allergy Institute, Ann and Robert H. Lurie Children's Hospital of Chicago","keywords":"Medicine; Ototoxicity; Common Terminology Criteria for Adverse Events; Concordance; Hearing loss; Carboplatin; Neuroblastoma; Grading (engineering); Population; Internal medicine; Cisplatin; Pediatrics; Audiology; Adverse effect; Chemotherapy","authors":[{"name":"Wendy Landier","is_ca":false},{"name":"Kristin R. Knight","is_ca":false},{"name":"F. Lennie Wong","is_ca":false},{"name":"Jin Lee","is_ca":false},{"name":"Ola Thomas","is_ca":false},{"name":"Heeyoung Kim","is_ca":false},{"name":"Susan G. Kreissman","is_ca":false},{"name":"Mary Lou Schmidt","is_ca":false},{"name":"Lu Chen","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"James G. Gurney","is_ca":false},{"name":"Ravi Bhatia","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02927050104966246,"gpt":0.3657615924739496,"spread":0.3364910914242871,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001612786,0.0002740867,0.0003129814,0.001111143,0.0002526156,0.000420552,0.0002734882,0.000396356,0.0003664187],"category_scores_gemma":[0.005091778,0.0001535423,0.0004220798,0.001162115,0.0003778769,0.0003050731,0.0004269905,0.0003887061,0.000107048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006253315,"about_ca_system_score_gemma":0.0004460882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007283022,"about_ca_topic_score_gemma":0.007957767,"domain_scores_codex":[0.9985558,0.0002957266,0.0002609696,0.0001930211,0.0006047014,0.00008980888],"domain_scores_gemma":[0.9954953,0.001539043,0.001858451,0.0001545805,0.0007480254,0.0002046258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003133604,0.00000561384,0.9973858,0.00001762967,0.00002385087,0.00008517799,0.00005117827,0.00002670704,0.00006594215,0.00000410731,0.0001292128,0.002173413],"study_design_scores_gemma":[0.000005885121,0.00005658525,0.9977043,0.00002168519,0.00003507298,0.001510289,0.0001319182,0.00007430198,0.0001702259,0.000006313507,0.0002793806,0.000003957894],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99626,0.002302275,0.0002010164,0.00008395744,0.0000091659,0.00002196802,0.00059264,0.00001121757,0.0005177472],"genre_scores_gemma":[0.9983801,0.0008685887,0.0001887598,0.00003093834,0.000008460369,0.00001967701,0.000461476,0.000002688455,0.00003942172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007283022,"threshold_uncertainty_score":0.01448131,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2027625542","doi":"10.1038/sj.onc.1206160","title":"A human brain tumor-derived PDGFR-α deletion mutant is transforming","year":2003,"lang":"en","type":"article","venue":"Oncogene","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Platelet-derived growth factor receptor; Mutant; Receptor tyrosine kinase; Cancer research; Molecular biology; Growth factor receptor; Transfection; Signal transduction; Cell biology; Cell growth; Receptor; Tyrosine kinase; Cell culture; Growth factor; Gene; Genetics","authors":[{"name":"Ian D. Clarke","is_ca":false},{"name":"Peter Dirks","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02806177110473869,"gpt":0.3188180201856512,"spread":0.2907562490809125,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002145213,0.0004982451,0.0002918307,0.000363773,0.0003086289,0.0004105741,0.0002874317,0.0003392906,0.002899047],"category_scores_gemma":[0.0002319214,0.0001972632,0.0003092672,0.0003485137,0.0002503328,0.0001895086,0.0001892127,0.0006976307,0.001407985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003286147,"about_ca_system_score_gemma":0.0003778637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001877007,"about_ca_topic_score_gemma":0.001262219,"domain_scores_codex":[0.9997752,0.00003070768,0.0000293095,0.00003865048,0.00006243677,0.00006367842],"domain_scores_gemma":[0.9997099,0.0001111748,0.00005159756,0.00005031441,0.00002161504,0.00005538551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001499413,0.00003881857,0.0002060297,0.00001973345,0.000008541013,0.0003805438,0.00002869452,0.00009558921,0.997663,0.0005373935,0.00009218412,0.0007794513],"study_design_scores_gemma":[0.00003151948,0.0001917669,0.002880515,0.000007901912,0.00002521825,0.001959664,0.00008318815,0.0008615822,0.9886417,0.0001525505,0.005157989,0.000006472372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897836,0.0006565517,0.003043603,0.0001622657,0.0001079671,0.00004416532,0.001502365,0.00009744828,0.00460199],"genre_scores_gemma":[0.9910107,0.0004989988,0.001798589,0.00003080113,0.00001295821,0.00002559486,0.002249071,0.00004278386,0.004330517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002899047,"threshold_uncertainty_score":0.009698272,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012716786","doi":"10.1016/s1476-5586(03)80017-9","title":"Chromosomal Localization of DNA Amplifications in Neuroblastoma Tumors Using cDNA Microarray Comparative Genomic Hybridization","year":2003,"lang":"en","type":"article","venue":"Neoplasia","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Comparative genomic hybridization; Amplicon; Biology; Copy number analysis; Copy-number variation; Complementary DNA; Microarray; Genetics; Gene duplication; Microarray analysis techniques; Gene expression profiling; Gene; Gene dosage; Neuroblastoma; Chromosome; Computational biology; Molecular biology; Genome; Polymerase chain reaction; Gene expression","authors":[{"name":"Ben Beheshti","is_ca":true},{"name":"Ilan Braude","is_ca":true},{"name":"Paula Marrano","is_ca":true},{"name":"Paul S. Thorner","is_ca":true},{"name":"Maria Zieleńska","is_ca":true},{"name":"Jeremy A. Squire","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03972326601490615,"gpt":0.3088302847914496,"spread":0.2691070187765435,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004229517,0.0003387815,0.0004183446,0.001256971,0.0003934932,0.0003648018,0.0003062437,0.0003167224,0.001795219],"category_scores_gemma":[0.0007449868,0.0002708771,0.0003176659,0.00103136,0.0002665793,0.0002280905,0.0002276312,0.000511217,0.0006759845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000558427,"about_ca_system_score_gemma":0.0003991357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00148398,"about_ca_topic_score_gemma":0.002472437,"domain_scores_codex":[0.9995448,0.00006399342,0.00003650996,0.0001719994,0.0001264961,0.00005622074],"domain_scores_gemma":[0.9997122,0.0001309323,0.00003740356,0.00003614324,0.00006168193,0.0000216254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00009449421,0.00001555341,0.0007230879,0.0000663099,0.000007603914,0.0000520324,0.00003942592,0.000465555,0.9930374,0.0001332825,0.00007280336,0.005292507],"study_design_scores_gemma":[0.00002964314,0.0002829333,0.03455155,0.00001990742,0.00007596354,0.0005742016,0.0001229531,0.01144503,0.945691,0.0004213166,0.006757336,0.00002807664],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8191366,0.002814223,0.1600796,0.0002934173,0.00009557897,0.0007394672,0.008901344,0.00194959,0.005990164],"genre_scores_gemma":[0.6968701,0.003179352,0.2809306,0.0001524354,0.00003542717,0.001626011,0.01105211,0.0002002944,0.00595358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001795219,"threshold_uncertainty_score":0.006005645,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1529762244","doi":"10.1002/pbc.24777","title":"Neuroblastoma in older children, adolescents and young adults: A report from the International Neuroblastoma Risk Group project","year":2013,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"William Guy Forbeck Research Foundation; St. Baldrick's Foundation","keywords":"Medicine; Neuroblastoma; Disease; Internal medicine; Stage (stratigraphy); Oncology; Proportional hazards model; Pediatrics","authors":[{"name":"Yaël P. Mossé","is_ca":false},{"name":"Rebecca Deyell","is_ca":true},{"name":"Frank Berthold","is_ca":false},{"name":"Akira Nagakawara","is_ca":false},{"name":"Peter F. Ambros","is_ca":false},{"name":"Tom Monclair","is_ca":false},{"name":"Susan L. Cohn","is_ca":false},{"name":"Andrew D.J. Pearson","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006112650145269083,"gpt":0.2484073045570639,"spread":0.2422946544117948,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006735107,0.0002501584,0.0002507585,0.0009721822,0.0003055875,0.0002860223,0.000208738,0.0002123683,0.000422617],"category_scores_gemma":[0.001110014,0.0001177895,0.0002388014,0.001188201,0.00012664,0.0002379391,0.0004340993,0.0002739893,0.0001312252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003231431,"about_ca_system_score_gemma":0.0007542723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02110999,"about_ca_topic_score_gemma":0.01858202,"domain_scores_codex":[0.999757,0.00003799066,0.00003410554,0.00003587162,0.00009173619,0.00004332988],"domain_scores_gemma":[0.9992563,0.00009635686,0.0003082164,0.0000351992,0.0001484837,0.0001555304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000155454,0.000008233761,0.9975713,0.0000106161,0.00001218823,0.00009430431,0.00008732792,0.00002138396,0.00003123593,0.00001092107,0.0004804136,0.001656513],"study_design_scores_gemma":[0.000004200377,0.0000233376,0.9983538,0.00001704109,0.00002079334,0.0003476967,0.0002780511,0.00003997943,0.00002698753,0.000009830137,0.0008759205,0.000002318646],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922236,0.001024732,0.000131586,0.0002247825,0.0000167341,0.00005397826,0.004764674,0.00001081912,0.001549026],"genre_scores_gemma":[0.9911282,0.00158986,0.0002689211,0.00012704,0.00003115899,0.0001030246,0.006403193,0.00000481538,0.0003437517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02110999,"threshold_uncertainty_score":0.04197425,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011386610","doi":"10.1093/jnci/92.3.253","title":"Delivery of c-myb Antisense Oligodeoxynucleotides to Human Neuroblastoma Cells Via Disialoganglioside GD2-Targeted Immunoliposomes: Antitumor Effects","year":2000,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Neuroblastoma; Liposome; Molecular biology; Biology; Monoclonal antibody; Western blot; Cationic liposome; In vitro; In vivo; Antibody; Cell culture; Biochemistry; Immunology; Transfection","authors":[{"name":"Gabriella Pagnan","is_ca":true},{"name":"Darrin D. Stuart","is_ca":true},{"name":"Fabio Pastorino","is_ca":true},{"name":"Lizzia Raffaghello","is_ca":true},{"name":"Paolo G. Montaldo","is_ca":true},{"name":"Theresa M. Allen","is_ca":true},{"name":"Bruno Calabretta","is_ca":true},{"name":"Mirco Ponzoni","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01836404277908087,"gpt":0.3112103005800679,"spread":0.2928462578009871,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001996082,0.000381948,0.0002380203,0.0001018579,0.00008414138,0.0002161923,0.0001623322,0.0003524341,0.0003873771],"category_scores_gemma":[0.0000902008,0.000125113,0.0001533274,0.00007995866,0.0001718953,0.0001735015,0.0001670598,0.000315442,0.0002009313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004326688,"about_ca_system_score_gemma":0.0002665887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008435542,"about_ca_topic_score_gemma":0.001357459,"domain_scores_codex":[0.9999117,0.00001527287,0.000008994895,0.00002655122,0.00002031593,0.00001726632],"domain_scores_gemma":[0.9999564,0.00001028281,0.00001053024,0.000003669423,0.000008831868,0.000010315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006118797,0.00001481232,0.00006809061,0.00003977061,0.000003760516,0.00001562477,0.000009450194,0.00008091152,0.9986896,0.00003856998,0.00002512649,0.0009531588],"study_design_scores_gemma":[0.00002837739,0.0002731296,0.0007450694,0.00000343725,0.00001541253,0.00009086083,0.000005106116,0.0006916515,0.996632,0.000009783787,0.00150209,0.000002967623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888666,0.002995926,0.006494206,0.00009022641,0.00003180363,0.00009399598,0.0002412315,0.00008191262,0.001104081],"genre_scores_gemma":[0.9879004,0.001864136,0.0078092,0.00006642,0.00001383803,0.00009924857,0.0003593247,0.00002184594,0.001865541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008435542,"threshold_uncertainty_score":0.003139257,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1972000776","doi":"10.1158/0008-5472.can-10-2484","title":"Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"PLK1; Cancer research; Neuroblastoma; Cytotoxic T cell; Kinase; Polo-like kinase; Biology; PI3K/AKT/mTOR pathway; Protein kinase B; Aurora kinase; Stem cell; Cancer; Medicine; Internal medicine; Cell cycle; Signal transduction; Cell biology; Cell culture; In vitro; Biochemistry","authors":[{"name":"Natalie Grinshtein","is_ca":true},{"name":"Alessandro Datti","is_ca":true},{"name":"Mayumi Fujitani","is_ca":true},{"name":"David Uehling","is_ca":true},{"name":"Michaël Prakesch","is_ca":true},{"name":"Methvin Isaac","is_ca":true},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Rima Al‐awar","is_ca":true},{"name":"David R. Kaplan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1219783853322647,"gpt":0.3743966627450988,"spread":0.2524182774128341,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001825557,0.0004417712,0.0007751121,0.0004729958,0.0002108786,0.0004164207,0.0003025774,0.0002752119,0.00197988],"category_scores_gemma":[0.0001465536,0.0001872021,0.0002861303,0.000380716,0.0001332369,0.0001232354,0.0001528142,0.0003882833,0.0005813645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003983061,"about_ca_system_score_gemma":0.0004224477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007891674,"about_ca_topic_score_gemma":0.003711739,"domain_scores_codex":[0.9998893,0.00001616711,0.0000105884,0.00002457002,0.00004091356,0.00001854783],"domain_scores_gemma":[0.9999257,0.00002252981,0.00001309212,0.000005407903,0.00001228859,0.00002088778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002892625,0.0001588405,0.0007954212,0.0001413834,0.00003053687,0.0001786192,0.00001303932,0.0005073042,0.9901274,0.000103643,0.0002915037,0.007362946],"study_design_scores_gemma":[0.0002958911,0.002978925,0.01013641,0.00002694632,0.0002431227,0.001094962,0.00004006177,0.002502884,0.9742113,0.00007519458,0.008375521,0.0000187899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706524,0.01262265,0.005305455,0.0003252632,0.00006041488,0.0005801828,0.002796166,0.0003144571,0.007342998],"genre_scores_gemma":[0.97216,0.009916754,0.00759001,0.0002040154,0.00001779076,0.0002640826,0.004487905,0.00003845662,0.005320962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00197988,"threshold_uncertainty_score":0.006623387,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2095202886","doi":"10.1038/cdd.2010.187","title":"CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression","year":2011,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Office of Science; National Cancer Institute; National Institutes of Health; Newcastle University; University of Oregon; McGill University","keywords":"Biology; Carcinogenesis; Neural crest; Neuroblastoma; Loss of heterozygosity; Cancer research; Epigenetics; Reprogramming; Transcription factor; Cell fate determination; Zinc finger; Gene expression; Enhancer; Zinc finger transcription factor; Tumor suppressor gene; Gene expression profiling; Cell biology; Gene; Genetics; Cell culture","authors":[{"name":"Z Liu","is_ca":false},{"name":"Xinyun Yang","is_ca":false},{"name":"Z Li","is_ca":false},{"name":"C. Geraldine McMahon","is_ca":false},{"name":"Caroline Sizer","is_ca":false},{"name":"Linda Barenboim‐Stapleton","is_ca":false},{"name":"Val Bliskovsky","is_ca":false},{"name":"Beverly A. Mock","is_ca":false},{"name":"Thomas Ried","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"John M. Maris","is_ca":false},{"name":"Javed Khan","is_ca":false},{"name":"Carol J. Thiele","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02753566293484423,"gpt":0.2549909809669525,"spread":0.2274553180321083,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232479,0.0003541389,0.0003382333,0.0004702423,0.0002444814,0.0003391215,0.0003288829,0.0002732281,0.001327398],"category_scores_gemma":[0.0001413545,0.0001320473,0.0002092461,0.0002149658,0.0003429959,0.0001573417,0.0001655925,0.0005746938,0.0003204009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005699875,"about_ca_system_score_gemma":0.0003818432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001077194,"about_ca_topic_score_gemma":0.002039331,"domain_scores_codex":[0.9998658,0.00001184819,0.00001081258,0.00003394744,0.00004891524,0.00002875573],"domain_scores_gemma":[0.9999195,0.00001881124,0.00002386489,0.000008516295,0.000007316909,0.00002202648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001191738,0.00002147151,0.0002034279,0.00001993536,0.000004213179,0.00005737006,0.000007963294,0.00007815546,0.9973347,0.0002416326,0.00009514745,0.00181696],"study_design_scores_gemma":[0.00002504665,0.00008755815,0.001699643,0.000002254727,0.00001566356,0.0002772172,0.00001870966,0.001145226,0.9937597,0.00006938115,0.002896116,0.000003527291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876719,0.002128458,0.00445308,0.0003309947,0.0001102401,0.00004057643,0.0006803165,0.000337388,0.004247081],"genre_scores_gemma":[0.9932933,0.0006498935,0.001639396,0.000046697,0.000009798413,0.00002026234,0.0004888913,0.00003924665,0.00381256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001327398,"threshold_uncertainty_score":0.004440606,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2165240249","doi":"10.1523/jneurosci.20-20-07648.2000","title":"Evidence That Helix-Loop-Helix Proteins Collaborate with Retinoblastoma Tumor Suppressor Protein to Regulate Cortical Neurogenesis","year":2000,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Killam Trusts","keywords":"Neurogenesis; Biology; Retinoblastoma protein; Progenitor cell; Transcription factor; Cell biology; Retinoblastoma; Basic helix-loop-helix; Mitosis; Progenitor; Cell cycle; Neuroscience; Gene; Genetics; DNA-binding protein; Stem cell","authors":[{"name":"Jean G. Toma","is_ca":true},{"name":"H. El‐Bizri","is_ca":true},{"name":"Fanie Barnabé‐Heider","is_ca":true},{"name":"Raquel Aloyz","is_ca":true},{"name":"Freda D. Miller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04309086530758606,"gpt":0.3023009492542991,"spread":0.2592100839467131,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003609735,0.0004476671,0.0002382635,0.0003610565,0.0002664855,0.0004070489,0.0003438468,0.0003779075,0.0008317307],"category_scores_gemma":[0.0003259957,0.0001962637,0.0001940939,0.0001839755,0.0004187985,0.0004101739,0.0004680811,0.0003393548,0.0005254957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003148913,"about_ca_system_score_gemma":0.000286244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004634406,"about_ca_topic_score_gemma":0.0007406973,"domain_scores_codex":[0.9997556,0.00004335288,0.00001704693,0.00004846651,0.0000794554,0.00005603254],"domain_scores_gemma":[0.9996533,0.00009176028,0.0000747363,0.00005716242,0.00004147185,0.00008150579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002475804,0.00002750067,0.002107305,0.00009465721,0.00001588243,0.0002614647,0.00002641503,0.0001016972,0.9944677,0.0006248627,0.00008408893,0.001940831],"study_design_scores_gemma":[0.00008504661,0.0002567955,0.0220689,0.00001491855,0.0000501422,0.001937815,0.00009361704,0.001053648,0.9689214,0.0005964118,0.004913509,0.000007848654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778932,0.0107881,0.005369151,0.0002968536,0.00003728458,0.0000236166,0.0002097817,0.0001070937,0.005274924],"genre_scores_gemma":[0.9938731,0.002459839,0.002181107,0.00006664623,0.00001683693,0.00001331447,0.0001928217,0.0000132347,0.001183127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008317307,"threshold_uncertainty_score":0.002782404,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2493582367","doi":"10.1016/j.ejca.2016.06.005","title":"Prognostic significance of pattern and burden of metastatic disease in patients with stage 4 neuroblastoma: A study from the International Neuroblastoma Risk Group database","year":2016,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute for Clinical Evaluative Sciences; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Sick Kids Foundation; William Guy Forbeck Research Foundation; Super Jake Foundation; Children's Neuroblastoma Cancer Foundation","keywords":"Neuroblastoma; Medicine; Oncology; Stage (stratigraphy); Disease; Internal medicine; Database; Computer science; Biology","authors":[{"name":"Daniel A. Morgenstern","is_ca":true},{"name":"Wendy B. London","is_ca":false},{"name":"Derek Stephens","is_ca":true},{"name":"Samuel L. Volchenboum","is_ca":false},{"name":"Thorsten Simon","is_ca":false},{"name":"Akira Nakagawara","is_ca":false},{"name":"Hiroyuki Shimada","is_ca":false},{"name":"Gudrun Schleiermacher","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false},{"name":"Susan L. Cohn","is_ca":false},{"name":"Andrew D.J. Pearson","is_ca":false},{"name":"Meredith S. Irwin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01454905375888124,"gpt":0.2666189714566038,"spread":0.2520699176977226,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003499555,0.000234959,0.0005015102,0.001122744,0.0003506112,0.0005731889,0.0005731256,0.0003916994,0.001373348],"category_scores_gemma":[0.002031488,0.0002117904,0.0006022626,0.002167273,0.0001743883,0.0006290487,0.0007509044,0.0004177012,0.000170178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004920109,"about_ca_system_score_gemma":0.0005107297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01369263,"about_ca_topic_score_gemma":0.02083868,"domain_scores_codex":[0.9996471,0.00006153475,0.00006604642,0.00009749083,0.00006616077,0.00006171157],"domain_scores_gemma":[0.998982,0.0001404895,0.0005359486,0.00008865136,0.00009889859,0.000154088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008368046,0.000005567889,0.9990973,0.000007862045,0.0000643586,0.00004088915,0.00002659483,0.00003396691,0.00005397481,0.0000130091,0.0001345877,0.0004382603],"study_design_scores_gemma":[0.000006425673,0.00001700893,0.9992132,0.000006738731,0.00005166092,0.0002137175,0.0001114606,0.0001133823,0.00002320723,0.00002236332,0.0002173167,0.000003495318],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950826,0.0003689329,0.00003982431,0.00005082689,0.000004591488,0.000005876383,0.004013308,0.000003349958,0.0004306718],"genre_scores_gemma":[0.9927126,0.0002823754,0.00007715872,0.00002642767,0.000008103731,0.00001383282,0.006720956,0.000003242978,0.0001553307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01369263,"threshold_uncertainty_score":0.02722585,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2017530122","doi":"10.1210/jcem.85.5.6589","title":"Pediatric Adrenocortical Tumors: Molecular Events Leading to Insulin-Like Growth Factor II Gene Overexpression*","year":2000,"lang":"en","type":"review","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Loss of heterozygosity; Endocrinology; Internal medicine; Virilization; Biology; Insulin-like growth factor 2; Locus (genetics); DNA methylation; Cancer research; Medicine; Gene expression; Gene; Genetics; Allele; Androgen","authors":[{"name":"Françoise Wilkin","is_ca":true},{"name":"Nancy Gagné","is_ca":true},{"name":"Jean Paquette","is_ca":true},{"name":"Luc L. Oligny","is_ca":true},{"name":"Cheri Deal","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08955589143194263,"gpt":0.4380596241869682,"spread":0.3485037327550256,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001325343,0.000333247,0.0001722132,0.0005140246,0.0002811854,0.0003767003,0.0001637541,0.0004855743,0.0009033711],"category_scores_gemma":[0.0005354061,0.0002599447,0.0002013431,0.0003925831,0.0002777769,0.0002898976,0.0002144019,0.0004608999,0.0002814694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003244346,"about_ca_system_score_gemma":0.0001703517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001006059,"about_ca_topic_score_gemma":0.001458809,"domain_scores_codex":[0.9999009,0.00001313101,0.00001017333,0.00001885276,0.00002217517,0.0000347605],"domain_scores_gemma":[0.999486,0.0001244852,0.0002131537,0.00002271043,0.00003912833,0.000114574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003961761,0.00006075452,0.6640028,0.00009921956,0.00003341841,0.1918537,0.0004537247,0.0004517466,0.1324612,0.0003840544,0.0003863443,0.009416883],"study_design_scores_gemma":[0.00003796642,0.0003235402,0.5943445,0.00002833954,0.0000714812,0.3705476,0.0004256972,0.00101848,0.02981666,0.0002092968,0.003160125,0.00001641578],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9970595,0.0007841753,0.001016541,0.00006118954,0.000008416793,0.00001226282,0.00008548184,0.00004067241,0.0009316314],"genre_scores_gemma":[0.9984971,0.0003457123,0.0008025669,0.00002358052,0.00001597911,0.000007757189,0.0001139534,0.00000684683,0.0001865022],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001006059,"threshold_uncertainty_score":0.003022075,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109781325","doi":"10.1093/aje/154.2.106","title":"Parental Occupational Exposures to Chemicals and Incidence of Neuroblastoma in Offspring","year":2001,"lang":"en","type":"article","venue":"American Journal of Epidemiology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Cancer Institute; National Institutes of Health","keywords":"Medicine; Odds ratio; Incidence (geometry); Confidence interval; Offspring; Neuroblastoma; Logistic regression; Occupational medicine; Environmental health; Demography; Toxicology; Occupational exposure; Pediatrics; Pregnancy; Internal medicine; Biology","authors":[{"name":"Anneclaire J. De Roos","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04013415342199754,"gpt":0.3809091050698951,"spread":0.3407749516478976,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006920604,0.0002353666,0.0002187838,0.0009320852,0.0002197926,0.00045206,0.0002712992,0.0002684828,0.0007462679],"category_scores_gemma":[0.003194154,0.0003381527,0.0003154393,0.0005309512,0.0002457324,0.0002184921,0.000252231,0.0003077712,0.00009226483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002924507,"about_ca_system_score_gemma":0.0001590555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007294269,"about_ca_topic_score_gemma":0.005593788,"domain_scores_codex":[0.9994246,0.000191239,0.0000446723,0.0001314986,0.0001471385,0.00006094345],"domain_scores_gemma":[0.9980683,0.0004966059,0.0008567591,0.0001736805,0.0002086327,0.0001960428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009115141,0.00001375401,0.9980873,0.000003966024,0.00003822454,0.000139829,0.0000474696,0.00003311906,0.0006014642,0.000009320498,0.0000185664,0.0009157893],"study_design_scores_gemma":[0.000004363576,0.000102228,0.9987782,0.000003560592,0.00003315213,0.0005733287,0.00003578725,0.00008150133,0.0002833815,0.000008994901,0.00009351973,0.000002016537],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990553,0.0004946304,0.0001114839,0.0000128474,0.000003216024,0.000002340187,0.0001062137,0.000004069116,0.0002098479],"genre_scores_gemma":[0.9993165,0.0002972604,0.000131098,0.000006266812,0.000004380847,0.000002979253,0.0001317153,0.000001766564,0.0001080811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007294269,"threshold_uncertainty_score":0.0145036,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2019034957","doi":"10.1097/00001648-200101000-00005","title":"Residential Pesticide Exposure and Neuroblastoma","year":2001,"lang":"en","type":"article","venue":"Epidemiology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Institute of Environmental Health Sciences; National Cancer Institute","keywords":"Neuroblastoma; Odds ratio; Confidence interval; Pesticide; Medicine; Cancer; Case-control study; Telephone interview; Pediatric oncology; Pediatrics; Environmental health; Internal medicine; Oncology; Biology","authors":[{"name":"Julie L. Daniels","is_ca":false},{"name":"Andrew F. Olshan","is_ca":false},{"name":"Kay Teschke","is_ca":true},{"name":"Irva Hertz‐Picciotto","is_ca":false},{"name":"David A. Savitz","is_ca":false},{"name":"Julie Blatt","is_ca":false},{"name":"Melissa L. Bondy","is_ca":false},{"name":"Joseph P. Neglia","is_ca":false},{"name":"Brad H. Pollock","is_ca":false},{"name":"Susan L. Cohn","is_ca":false},{"name":"A. Thomas Look","is_ca":false},{"name":"Robert C. Seeger","is_ca":false},{"name":"Robert P. Castleberry","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0510018118282187,"gpt":0.3560353324641762,"spread":0.3050335206359575,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003491734,0.000134982,0.0001923056,0.0007415903,0.000267194,0.0002636435,0.0001517383,0.0002498354,0.001586559],"category_scores_gemma":[0.002638685,0.0001518079,0.0002589152,0.001142743,0.0001446213,0.0002121797,0.0002786852,0.0002542393,0.000121682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002845896,"about_ca_system_score_gemma":0.0003762761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00927737,"about_ca_topic_score_gemma":0.01343437,"domain_scores_codex":[0.9995458,0.0001679261,0.00003669077,0.00007608407,0.0001269786,0.00004643444],"domain_scores_gemma":[0.9984367,0.0003625326,0.0008992848,0.00004493667,0.0001337461,0.0001226309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009379912,0.00002385648,0.9902809,0.0000748521,0.00009145559,0.0002059679,0.00006155704,0.00006193449,0.0002810204,0.00004793276,0.0002363569,0.008540377],"study_design_scores_gemma":[0.000004085829,0.0001069548,0.9977157,0.00002652062,0.00004357986,0.0009058229,0.00005279186,0.00004436711,0.0001327321,0.00005669998,0.0009083438,0.000002345878],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829807,0.0139197,0.0003093677,0.0002635861,0.00001493553,0.00001481443,0.0008325768,0.00001199791,0.001652395],"genre_scores_gemma":[0.9930987,0.005647176,0.0002827591,0.00003873639,0.00002433291,0.000009960535,0.0004413306,0.000001979845,0.0004551341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00927737,"threshold_uncertainty_score":0.01844674,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2758777848","doi":"10.1007/s00259-017-3829-7","title":"Validation of the mIBG skeletal SIOPEN scoring method in two independent high-risk neuroblastoma populations: the SIOPEN/HR-NBL1 and COG-A3973 trials","year":2017,"lang":"en","type":"article","venue":"European Journal of Nuclear Medicine and Molecular Imaging","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital","funders":"National Cancer Institute; Children's Neuroblastoma Cancer Foundation; Cancer Research UK; Alex's Lemonade Stand Foundation for Childhood Cancer; Cancer Research Institute","keywords":"Cog; Neuroblastoma; Medicine; Oncology; Internal medicine; Clinical trial; Computer science; Biology; Artificial intelligence; Genetics","authors":[{"name":"Ruth Ladenstein","is_ca":false},{"name":"Bieke Lambert","is_ca":false},{"name":"Ulrike Pötschger","is_ca":false},{"name":"Maria Rita Castellani","is_ca":false},{"name":"Valerie Lewington","is_ca":false},{"name":"Zvi Bar‐Sever","is_ca":false},{"name":"A. Oudoux","is_ca":false},{"name":"Anna Śliwińska","is_ca":false},{"name":"Kateřina Táborská","is_ca":false},{"name":"Lorenzo Biassoni","is_ca":false},{"name":"Gregory A. Yanik","is_ca":false},{"name":"Arlene Naranjo","is_ca":false},{"name":"Marguerite T. Parisi","is_ca":false},{"name":"Barry L. Shulkin","is_ca":false},{"name":"Helen Nadel","is_ca":true},{"name":"Michael J. Gelfand","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Susan G. Kreissman","is_ca":false},{"name":"Dominique Valteau‐Couanet","is_ca":false},{"name":"Ariane Boubaker","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05543207068529071,"gpt":0.3852522822265522,"spread":0.3298202115412615,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01145385,0.001734627,0.001965659,0.0005887339,0.0007136515,0.001620474,0.001224844,0.001333478,0.002002371],"category_scores_gemma":[0.007993907,0.0004719509,0.001624704,0.0007823693,0.001041156,0.001075446,0.001324242,0.001675978,0.001029083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009894964,"about_ca_system_score_gemma":0.001458696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003873753,"about_ca_topic_score_gemma":0.009706116,"domain_scores_codex":[0.9959452,0.002241167,0.000328636,0.0006934732,0.0005737206,0.0002179127],"domain_scores_gemma":[0.9966072,0.001067035,0.0006062905,0.0005784367,0.0007608329,0.0003802948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2435852,0.003316297,0.5155925,0.001219853,0.01604766,0.0005537899,0.001236426,0.007301996,0.04058536,0.001366532,0.01070644,0.158488],"study_design_scores_gemma":[0.04159947,0.02466105,0.8595258,0.0002233615,0.01375967,0.001466524,0.0005877961,0.00774257,0.01458769,0.002030226,0.03356399,0.0002519441],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836509,0.003309178,0.002790002,0.0006000579,0.0001587127,0.0009472617,0.003888912,0.00009307583,0.004561928],"genre_scores_gemma":[0.9796082,0.001080804,0.004166935,0.0005177599,0.000117345,0.001061491,0.01155727,0.000142392,0.001747804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01145385,"threshold_uncertainty_score":0.06057447,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1966169774","doi":"10.1159/000336483","title":"Metronomic Chemotherapy with the COMBAT Regimen in Advanced Pediatric Malignancies: A Multicenter Experience","year":2012,"lang":"en","type":"article","venue":"Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Medicine; Internal medicine; Regimen; Mitoxantrone; Progressive disease; Chemotherapy; Refractory (planetary science); Etoposide; Surgery","authors":[{"name":"Danica Zapletalová","is_ca":true},{"name":"Nicolás André","is_ca":false},{"name":"L. Deak","is_ca":false},{"name":"Michal Kýr","is_ca":true},{"name":"Viera Bajčiová","is_ca":true},{"name":"Peter Múdrý","is_ca":true},{"name":"Lenka Zdražilová Dubská","is_ca":false},{"name":"Regina Demlová","is_ca":false},{"name":"Zdeněk Pavelka","is_ca":true},{"name":"Karel Zitterbart","is_ca":true},{"name":"Jarmila Skotáková","is_ca":false},{"name":"K Husek","is_ca":false},{"name":"A. Martincekova","is_ca":true},{"name":"Pavel Mazánek","is_ca":true},{"name":"Tomáš Kepák","is_ca":true},{"name":"M. Doubek","is_ca":false},{"name":"Lucia Kútniková","is_ca":true},{"name":"Dalibor Valík","is_ca":false},{"name":"Jaroslav Štěrba","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01711074645537189,"gpt":0.3305496907564193,"spread":0.3134389443010475,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008453731,0.0003629079,0.0003519462,0.0002194199,0.0003016945,0.0004012645,0.0002507458,0.0002247836,0.0009710731],"category_scores_gemma":[0.0008880926,0.000116742,0.0003119403,0.0006030379,0.0003068045,0.000321458,0.0003530995,0.0004288273,0.0001957491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004940936,"about_ca_system_score_gemma":0.0005794485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008678094,"about_ca_topic_score_gemma":0.0008761754,"domain_scores_codex":[0.9995325,0.0002414612,0.00003988712,0.00006058274,0.00005337889,0.00007218163],"domain_scores_gemma":[0.9994987,0.0001075413,0.0001689227,0.00005003632,0.00003915235,0.0001355529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009342913,0.006013937,0.7487741,0.0004812042,0.0004529141,0.007102282,0.00234025,0.001928055,0.01519567,0.00073131,0.004415383,0.203222],"study_design_scores_gemma":[0.006187568,0.07193174,0.8059924,0.0002898014,0.0007940339,0.05299535,0.002201456,0.002430016,0.01511139,0.0003137409,0.04169013,0.00006241568],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961745,0.002457839,0.0002772032,0.0001069926,0.000008925012,0.00007036145,0.000137585,0.000008602612,0.0007579568],"genre_scores_gemma":[0.9950837,0.003048271,0.0009795249,0.00009353455,0.00004843724,0.00007756853,0.0004899973,0.000009589133,0.000169503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009710731,"threshold_uncertainty_score":0.004470825,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3179702411","doi":"10.1200/jco.21.00703","title":"Randomized Phase II Trial of MIBG Versus MIBG, Vincristine, and Irinotecan Versus MIBG and Vorinostat for Patients With Relapsed or Refractory Neuroblastoma: A Report From NANT Consortium","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute","keywords":"Medicine; Vincristine; Neuroblastoma; Refractory (planetary science); Irinotecan; Clinical endpoint; Internal medicine; Surgery; Vorinostat; Randomized controlled trial; Chemotherapy; Cyclophosphamide; Oncology; Cancer","authors":[{"name":"Steven G. DuBois","is_ca":false},{"name":"Meaghan Granger","is_ca":false},{"name":"Susan Groshen","is_ca":false},{"name":"Denice Tsao‐Wei","is_ca":false},{"name":"Lingyun Ji","is_ca":false},{"name":"Anasheh Shamirian","is_ca":false},{"name":"Scarlett Czarnecki","is_ca":false},{"name":"Fariba Goodarzian","is_ca":false},{"name":"Rachel Berkovich","is_ca":false},{"name":"Hiroyuki Shimada","is_ca":false},{"name":"Judith G. Villablanca","is_ca":false},{"name":"Kieuhoa T. Vo","is_ca":false},{"name":"Navin Pinto","is_ca":false},{"name":"Yaël P. Mossé","is_ca":false},{"name":"John M. Maris","is_ca":false},{"name":"Suzanne Shusterman","is_ca":false},{"name":"Susan L. Cohn","is_ca":false},{"name":"Kelly C. Goldsmith","is_ca":false},{"name":"Brian Weiss","is_ca":false},{"name":"Gregory A. Yanik","is_ca":false},{"name":"Clare J. Twist","is_ca":false},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Daphne A. Haas‐Kogan","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Araz Marachelian","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1137092475981462,"gpt":0.4651826797140354,"spread":0.3514734321158892,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002943382,0.001399315,0.002123328,0.0003744915,0.000408739,0.0008393596,0.0007791102,0.001880131,0.004354118],"category_scores_gemma":[0.001853756,0.0005553007,0.001272939,0.0003187964,0.001179868,0.0007141304,0.0003481791,0.00255595,0.0006303609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008987701,"about_ca_system_score_gemma":0.001734935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001096394,"about_ca_topic_score_gemma":0.002857302,"domain_scores_codex":[0.9988532,0.0008251642,0.0000427791,0.0001166918,0.00006114933,0.0001010264],"domain_scores_gemma":[0.998773,0.0004342267,0.0002271358,0.0000725971,0.0000536893,0.0004391967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9703541,0.00699083,0.001260786,0.0002623856,0.0005485761,0.00005846067,0.00007121733,0.0006026119,0.003528736,0.0001807779,0.001647575,0.01449395],"study_design_scores_gemma":[0.9390723,0.05782508,0.001086,0.00001954339,0.0001851118,0.00002965033,0.00001695704,0.0004973477,0.0003453257,0.0001383648,0.0007755443,0.00000872193],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814656,0.00310792,0.0008878651,0.002122231,0.0006973959,0.007353673,0.001415721,0.0001153819,0.002834261],"genre_scores_gemma":[0.973777,0.002059343,0.002583696,0.004076463,0.0007383393,0.008776266,0.002160085,0.00004020405,0.005788682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004354118,"threshold_uncertainty_score":0.01556629,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2168240861","doi":"10.1002/pbc.20777","title":"Evaluation of semi‐quantitative scoring system for metaiodobenzylguanidine (mIBG) scans in patients with relapsed neuroblastoma","year":2006,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Center for Research Resources; National Cancer Institute; Frank A. Campini Foundation; University of California, San Francisco; Dougherty Foundation; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Medicine; Concordance; Scoring system; Neuroblastoma; Soft tissue; Correlation; Concordance correlation coefficient; Internal medicine; Nuclear medicine; Radiology; Surgery; Statistics","authors":[{"name":"Julia A. Messina","is_ca":false},{"name":"Su‐Chun Cheng","is_ca":false},{"name":"Benjamin L. Franc","is_ca":false},{"name":"Martin Charron","is_ca":true},{"name":"Barry L. Shulkin","is_ca":false},{"name":"Bao To","is_ca":false},{"name":"John M. Maris","is_ca":false},{"name":"Gregory A. Yanik","is_ca":false},{"name":"Randall A. Hawkins","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02344335902251954,"gpt":0.2967891252404305,"spread":0.273345766217911,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004287632,0.0003917972,0.0003444451,0.001454433,0.0001941752,0.0005585489,0.0004202928,0.0004680161,0.0006829922],"category_scores_gemma":[0.01373891,0.0001784303,0.0002592794,0.0004902556,0.0003014153,0.000417656,0.0004458077,0.0002798612,0.0003428887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002478316,"about_ca_system_score_gemma":0.0002057069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005929218,"about_ca_topic_score_gemma":0.0008705984,"domain_scores_codex":[0.9975345,0.001120442,0.0003074867,0.0002837541,0.0006557672,0.0000979069],"domain_scores_gemma":[0.9924068,0.003137337,0.001643077,0.0005279541,0.001971707,0.0003131766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00145743,0.0000958116,0.9563407,0.00009811149,0.0001331167,0.000158828,0.0003163941,0.0006566394,0.01213947,0.00004735805,0.0003226541,0.02823352],"study_design_scores_gemma":[0.0001002893,0.001237896,0.9710761,0.00002943514,0.0001271293,0.001685674,0.0003323142,0.01484631,0.009452759,0.0001044598,0.0009697914,0.00003766421],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942879,0.0005054584,0.004102323,0.00003238081,0.00001828966,0.0000617511,0.0001540231,0.00005789323,0.0007800686],"genre_scores_gemma":[0.9956294,0.00007054476,0.003825946,0.00001593022,0.00001225164,0.00005204274,0.0002412551,0.000007812379,0.0001447646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004287632,"threshold_uncertainty_score":0.02267545,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2156902079","doi":"10.1158/1078-0432.ccr-11-0078","title":"Metronomic Oral Topotecan with Pazopanib Is an Active Antiangiogenic Regimen in Mouse Models of Aggressive Pediatric Solid Tumor","year":2011,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; Hospital for Sick Children; University of Toronto; Sunnybrook Health Science Centre","funders":"National Cancer Institute","keywords":"Pazopanib; Topotecan; Medicine; Pharmacology; Angiogenesis; In vivo; Neuroblastoma; Cancer research; Pharmacokinetics; Rhabdomyosarcoma; Cancer; Chemotherapy; Oncology; Sarcoma; Internal medicine; Cell culture; Biology; Sunitinib; Pathology","authors":[{"name":"Sushil Kumar","is_ca":true},{"name":"Reza Bayat Mokhtari","is_ca":true},{"name":"Reihaneh Sheikh","is_ca":true},{"name":"Bing Wu","is_ca":true},{"name":"Libo Zhang","is_ca":true},{"name":"Ping Xu","is_ca":true},{"name":"Shan Man","is_ca":true},{"name":"Indhira Dias Oliveira","is_ca":true},{"name":"Herman Yeger","is_ca":true},{"name":"Robert S. Kerbel","is_ca":true},{"name":"Sylvain Baruchel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3053773045261252,"gpt":0.4944461548165539,"spread":0.1890688502904287,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003843848,0.0009351564,0.0008192179,0.0007003696,0.000241847,0.0004262855,0.000462574,0.0004592109,0.0008837878],"category_scores_gemma":[0.0001197792,0.0002994738,0.0004496021,0.0004486108,0.0004160849,0.0005148572,0.000160884,0.001748105,0.0002448065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007356573,"about_ca_system_score_gemma":0.0006597234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00138063,"about_ca_topic_score_gemma":0.003439634,"domain_scores_codex":[0.9995641,0.00008672162,0.0000297233,0.0000700439,0.0001441438,0.0001052651],"domain_scores_gemma":[0.9998023,0.00001990737,0.00005907756,0.00002894206,0.00001403932,0.00007575775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002418363,0.002105912,0.0009960186,0.000130641,0.0000521124,0.0001378502,0.00005241325,0.0009127095,0.9835821,0.0002415546,0.0003705474,0.008999867],"study_design_scores_gemma":[0.0005215789,0.02245087,0.00662609,0.00001426495,0.00009164147,0.0004231628,0.00003777699,0.002533101,0.9636387,0.00005074508,0.003597564,0.00001458164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942759,0.001410172,0.002016525,0.0001374861,0.00006527419,0.000244552,0.0006740784,0.0001650185,0.001011091],"genre_scores_gemma":[0.9912007,0.001559068,0.003843115,0.00005320766,0.00003069457,0.0003574032,0.0009973763,0.00002718494,0.001931194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00138063,"threshold_uncertainty_score":0.005337596,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012687605","doi":"10.1097/mph.0b013e318299d637","title":"Current and Future Strategies for Relapsed Neuroblastoma","year":2013,"lang":"en","type":"review","venue":"Journal of Pediatric Hematology/Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Topotecan; Irinotecan; Oncology; Temozolomide; Immunotherapy; Internal medicine; Refractory (planetary science); Chemotherapy; Disease; Targeted therapy; Intensive care medicine; Cancer","authors":[{"name":"Daniel A. Morgenstern","is_ca":true},{"name":"Sylvain Baruchel","is_ca":true},{"name":"Meredith S. Irwin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06367707080064555,"gpt":0.4141367188244433,"spread":0.3504596480237978,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004756409,0.0007106263,0.0009723966,0.002292825,0.0003042984,0.0007043472,0.00081511,0.00101566,0.00494873],"category_scores_gemma":[0.0004953045,0.0002133334,0.0005714987,0.001361354,0.0003690123,0.001335224,0.0006350662,0.00183907,0.002683566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005578926,"about_ca_system_score_gemma":0.001019584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071523,"about_ca_topic_score_gemma":0.002601149,"domain_scores_codex":[0.9998622,0.00002535846,0.00002347662,0.00002210678,0.00005281973,0.00001403714],"domain_scores_gemma":[0.99983,0.00006522703,0.00002973994,0.000006232653,0.00004583539,0.00002286516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004754403,0.00008828456,0.0001405992,0.01096446,0.00005166475,0.0003566068,0.00006468653,0.0003242639,0.001150891,0.002962473,0.02565652,0.9581921],"study_design_scores_gemma":[0.00002400538,0.00008321794,0.0007341612,0.004282479,0.00008263651,0.002434093,0.00009083785,0.00008925513,0.0002990281,0.002528337,0.9893363,0.00001571202],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009675299,0.9980001,0.0001371324,0.0004587913,0.0001702824,0.000006990333,0.00001350544,0.000009305199,0.001107027],"genre_scores_gemma":[0.0005062533,0.9980469,0.0003481433,0.0003029427,0.0001405957,0.00001048176,0.00003222605,0.00000148252,0.0006109184],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00494873,"threshold_uncertainty_score":0.01655519,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2128653564","doi":"","title":"Targeted liposomal c-myc antisense oligodeoxynucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"In vivo; Melanoma; In vitro; Cancer research; Liposome; Oncogene; Neuroblastoma; Cationic liposome; Apoptosis; Monoclonal antibody; Medicine; Pharmacology; Biology; Immunology; Cell culture; Antibody; Transfection; Biochemistry; Cell cycle","authors":[{"name":"Fabio Pastorino","is_ca":false},{"name":"Chiara Brignole","is_ca":false},{"name":"Danilo Marimpietri","is_ca":false},{"name":"Gabriella Pagnan","is_ca":false},{"name":"Adriana Morando","is_ca":false},{"name":"Doménico Ribatti","is_ca":false},{"name":"Sean C. Semple","is_ca":false},{"name":"Claudio Gambini","is_ca":false},{"name":"Theresa M. Allen","is_ca":true},{"name":"Mirco Ponzoni","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02716445340812738,"gpt":0.2434002716511696,"spread":0.2162358182430422,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001045895,0.0004091694,0.0002134723,0.0001573188,0.0000789055,0.0001145479,0.0001278674,0.0002377531,0.0007554654],"category_scores_gemma":[0.00006259196,0.0000997306,0.000138223,0.00007624536,0.0001569171,0.0001198756,0.0001042531,0.0004154356,0.0002262846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002681587,"about_ca_system_score_gemma":0.0001908882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008661812,"about_ca_topic_score_gemma":0.001215577,"domain_scores_codex":[0.9999439,0.000009326542,0.000003990295,0.00001619397,0.00001537288,0.00001129989],"domain_scores_gemma":[0.9999665,0.000007105305,0.000008394305,0.000003698812,0.000006962927,0.000007485628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001761598,0.00007820794,0.00008224003,0.00005245913,0.000005494407,0.00001738903,0.0000109822,0.0001147182,0.9976113,0.00004824804,0.00005350859,0.001749392],"study_design_scores_gemma":[0.00006324175,0.00109418,0.0007808762,0.000004927177,0.00001477552,0.0001055462,0.000006710547,0.0009481206,0.9955419,0.00002086327,0.001416698,0.000002123065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883099,0.003787303,0.005314474,0.00009207052,0.00006702536,0.0001401826,0.0003116447,0.0001438411,0.001833566],"genre_scores_gemma":[0.991422,0.001715386,0.002925537,0.00005071158,0.000009992828,0.000107549,0.0003720906,0.0000200699,0.003376595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008661812,"threshold_uncertainty_score":0.002527237,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2752019124","doi":"10.2967/jnumed.117.195883","title":"Validation of Postinduction Curie Scores in High-Risk Neuroblastoma: A Children’s Oncology Group and SIOPEN Group Report on SIOPEN/HR-NBL1","year":2017,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital","funders":"National Cancer Institute","keywords":"Medicine; Neuroblastoma; Internal medicine; Group (periodic table); Oncology; Pediatric oncology; Medical physics; Cancer; Physics; Biology","authors":[{"name":"Gregory A. Yanik","is_ca":false},{"name":"Marguerite T. Parisi","is_ca":false},{"name":"Arlene Naranjo","is_ca":false},{"name":"Helen Nadel","is_ca":true},{"name":"Michael J. Gelfand","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Ruth Ladenstein","is_ca":false},{"name":"Ulrike Pöetschger","is_ca":false},{"name":"Ariane Boubaker","is_ca":false},{"name":"Dominique Valteau‐Couanet","is_ca":false},{"name":"Bieke Lambert","is_ca":false},{"name":"Maria Rita Castellani","is_ca":false},{"name":"Zvi Bar‐Sever","is_ca":false},{"name":"A. Oudoux","is_ca":false},{"name":"Anna Kamińska","is_ca":false},{"name":"Susan G. Kreissman","is_ca":false},{"name":"Barry L. Shulkin","is_ca":false},{"name":"Katherine K. Matthay","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02286401340540922,"gpt":0.327347591184418,"spread":0.3044835777790088,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004843017,0.000502314,0.0003838694,0.0006639466,0.0002896967,0.0008476885,0.0006905507,0.0003496975,0.0008463358],"category_scores_gemma":[0.007202855,0.0001710271,0.00033078,0.0009023516,0.0004357186,0.000338772,0.0007757103,0.0005291967,0.0003044211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001063811,"about_ca_system_score_gemma":0.001361949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009106823,"about_ca_topic_score_gemma":0.01716901,"domain_scores_codex":[0.9975944,0.0008916765,0.0001632478,0.0004446597,0.0007616642,0.0001441924],"domain_scores_gemma":[0.9941666,0.001642431,0.001491556,0.001232462,0.001077474,0.0003894985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003468104,0.0001085769,0.9658296,0.00007708713,0.00030298,0.0002003267,0.0002783368,0.001271386,0.006001299,0.000178634,0.003601537,0.01868228],"study_design_scores_gemma":[0.0002689434,0.0007410712,0.9833984,0.00002379036,0.0001454447,0.0006809693,0.00013727,0.001887961,0.0047213,0.00006249167,0.007910781,0.00002147455],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916855,0.000374567,0.0008138891,0.00009186191,0.00001808533,0.0001401138,0.00489116,0.00003220949,0.001952607],"genre_scores_gemma":[0.9746503,0.0002500206,0.002206418,0.00008448467,0.00002376282,0.0001898706,0.02188393,0.00005195338,0.0006594143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009106823,"threshold_uncertainty_score":0.02561259,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3016358793","doi":"10.1200/jco.19.03285","title":"Age, Diagnostic Category, Tumor Grade, and Mitosis-Karyorrhexis Index Are Independently Prognostic in Neuroblastoma: An INRG Project","year":2020,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; William Guy Forbeck Research Foundation; Bear Necessities Pediatric Cancer Foundation; Super Jake Foundation; Children’s Oncology Group; American Society of Clinical Oncology; St. Baldrick's Foundation; Rally Foundation; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Medicine; Karyorrhexis; Neuroblastoma; Mitotic index; Oncology; Pathology; Internal medicine; Mitosis","authors":[{"name":"Elizabeth Sokol","is_ca":false},{"name":"Ami V. Desai","is_ca":false},{"name":"Mark A. Applebaum","is_ca":false},{"name":"Dominique Valteau‐Couanet","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Andrew D.J. Pearson","is_ca":false},{"name":"Gudrun Schleiermacher","is_ca":false},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Michael D. Hogarty","is_ca":false},{"name":"Arlene Naranjo","is_ca":false},{"name":"Samuel L. Volchenboum","is_ca":false},{"name":"Susan L. Cohn","is_ca":false},{"name":"Wendy B. London","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1623469264939458,"gpt":0.4551598175571616,"spread":0.2928128910632158,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002095237,0.0003250352,0.0002524733,0.0006692391,0.0002714611,0.0005140621,0.0003887539,0.0001950845,0.0009331044],"category_scores_gemma":[0.002897428,0.0001107623,0.0005527789,0.0006219181,0.0002468245,0.0001898741,0.0005008987,0.0002870155,0.0002136293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006291643,"about_ca_system_score_gemma":0.0009810022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01604779,"about_ca_topic_score_gemma":0.01766707,"domain_scores_codex":[0.9993794,0.0002391239,0.00004111438,0.0001173767,0.0001203145,0.0001025993],"domain_scores_gemma":[0.9984562,0.0004273758,0.000443659,0.0002255882,0.0002190475,0.0002282276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002715456,0.00002194356,0.9952778,0.000006403272,0.00007375517,0.00004377783,0.00002018345,0.0001889559,0.0002126195,0.00002600016,0.0001821311,0.003675009],"study_design_scores_gemma":[0.00002557984,0.0001259569,0.9978278,0.00001106238,0.0001252829,0.0001988496,0.00005933968,0.0007958646,0.0002063027,0.0000568487,0.0005633131,0.000003643169],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997465,0.0004691641,0.0002687659,0.0001126097,0.000006091367,0.00001624958,0.001161155,0.000007069534,0.0004938191],"genre_scores_gemma":[0.9973196,0.0001995538,0.0004580587,0.00003005895,0.00001064847,0.000009116685,0.001688393,0.000004284542,0.0002801772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01604779,"threshold_uncertainty_score":0.03190881,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3042190218","doi":"10.1016/j.ejca.2020.05.010","title":"Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma","year":2020,"lang":"en","type":"review","venue":"European Journal of Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Fondation contre le Cancer; Vlaamse regering; Kom op tegen Kanker; Fonds Wetenschappelijk Onderzoek; National Cancer Institute; Cancer Research UK; Neuroblastoma UK; Oak Foundation; Olivia Fund; Instituto de Salud Carlos III; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Neuroblastoma; Medicine; Clinical trial; Drug development; Drug; ATRX; Oncology; Pharmacology; Internal medicine; Biology; Mutation; Genetics","authors":[{"name":"Lucas Moreno","is_ca":false},{"name":"Giuseppe Barone","is_ca":false},{"name":"Steven G. DuBois","is_ca":false},{"name":"Jan J. Molenaar","is_ca":false},{"name":"Matthias Fischer","is_ca":false},{"name":"Johannes H. Schulte","is_ca":false},{"name":"Angelika Eggert","is_ca":false},{"name":"Gudrun Schleiermacher","is_ca":false},{"name":"Frank Speleman","is_ca":false},{"name":"Louis Chesler","is_ca":false},{"name":"Birgit Geoerger","is_ca":false},{"name":"Michael D. Hogarty","is_ca":false},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Nick Bird","is_ca":false},{"name":"Guy B. Blanchard","is_ca":false},{"name":"Sean Buckland","is_ca":false},{"name":"Hubert Caron","is_ca":false},{"name":"Susan R. Davis","is_ca":false},{"name":"Bram De Wilde","is_ca":false},{"name":"Hedwig E. Deubzer","is_ca":false},{"name":"M. Emmy M. Dolman","is_ca":false},{"name":"Martin Eilers","is_ca":false},{"name":"Rani E. George","is_ca":false},{"name":"Sally L. George","is_ca":false},{"name":"Štěrba Jaroslav","is_ca":false},{"name":"John M. Maris","is_ca":false},{"name":"Lynley V. Marshall","is_ca":false},{"name":"Melinda S. Merchant","is_ca":false},{"name":"Peter G. Mortimer","is_ca":false},{"name":"Cormac Owens","is_ca":false},{"name":"Anna Philpott","is_ca":false},{"name":"Evon Poon","is_ca":false},{"name":"Jerry W. Shay","is_ca":false},{"name":"Roberto Tonelli","is_ca":false},{"name":"Dominique Valteau‐Couanet","is_ca":false},{"name":"Gilles Vassal","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Andrew D.J. Pearson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04454238105661854,"gpt":0.3303695918244042,"spread":0.2858272107677856,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002517712,0.0009824501,0.001525021,0.002641928,0.000287024,0.001490309,0.0008317438,0.001845447,0.004175178],"category_scores_gemma":[0.002025132,0.0003389673,0.001066893,0.002372432,0.0003050521,0.001614322,0.001084598,0.003059407,0.001532389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001795161,"about_ca_system_score_gemma":0.00531246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003258004,"about_ca_topic_score_gemma":0.009739438,"domain_scores_codex":[0.9995399,0.00007117195,0.00007106343,0.00005917323,0.0001850629,0.0000738087],"domain_scores_gemma":[0.9986909,0.0005486773,0.000193991,0.0000215677,0.0003917071,0.0001532758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001636538,0.0001187287,0.0001838443,0.02373695,0.0001269389,0.0001465963,0.00005850323,0.0004962531,0.001498505,0.005486303,0.1150381,0.8529455],"study_design_scores_gemma":[0.00006986045,0.0001491736,0.0006240832,0.008506615,0.0002072919,0.0003056418,0.0000284507,0.0001096138,0.0005007739,0.0008408328,0.9886409,0.00001679996],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001191484,0.995317,0.0001553254,0.001516515,0.001017756,0.00003047123,0.00009919491,0.00001357829,0.001731018],"genre_scores_gemma":[0.000492431,0.9967043,0.0003460281,0.001219407,0.0002866258,0.00002235562,0.0001111788,0.000003042312,0.0008146227],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004175178,"threshold_uncertainty_score":0.01396739,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2935510920","doi":"10.1016/j.ejca.2019.02.003","title":"Predictors of differential response to induction therapy in high-risk neuroblastoma: A report from the Children's Oncology Group (COG)","year":2019,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Institutes of Health; National Cancer Institute; St. Baldrick's Foundation","keywords":"Medicine; Internal medicine; Confidence interval; Odds ratio; Oncology; Neuroblastoma; Induction chemotherapy; Univariate analysis; Stage (stratigraphy); Logistic regression; Multivariate analysis; Chemotherapy; Biology","authors":[{"name":"Navin Pinto","is_ca":false},{"name":"Arlene Naranjo","is_ca":false},{"name":"Emily Hibbitts","is_ca":false},{"name":"Susan G. Kreissman","is_ca":false},{"name":"Meaghan Granger","is_ca":false},{"name":"Meredith S. Irwin","is_ca":true},{"name":"Rochelle Bagatell","is_ca":false},{"name":"Wendy B. London","is_ca":false},{"name":"Emily Greengard","is_ca":false},{"name":"Julie R. Park","is_ca":false},{"name":"Steven G. DuBois","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01246067678897274,"gpt":0.2864817174599867,"spread":0.274021040671014,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005286902,0.0001826532,0.0002975905,0.000487965,0.0003011709,0.0004465545,0.000252339,0.0003224974,0.0004508628],"category_scores_gemma":[0.002289512,0.00009657525,0.000273311,0.0009543916,0.0002062985,0.0001749152,0.0003090883,0.0004848572,0.00007871332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005900597,"about_ca_system_score_gemma":0.0007394648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01171569,"about_ca_topic_score_gemma":0.01126088,"domain_scores_codex":[0.9996866,0.0000665456,0.00003031198,0.0000489249,0.00008710136,0.00008053277],"domain_scores_gemma":[0.9987999,0.0004888824,0.0003249536,0.00004692651,0.0001578283,0.0001814806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008212579,0.000009232034,0.9981264,0.000003510286,0.00001177367,0.00008029384,0.00002355833,0.00005657551,0.0001417805,0.000007043719,0.0001244872,0.001333127],"study_design_scores_gemma":[0.00000543342,0.00003688371,0.9990004,0.000004149065,0.00003085828,0.0003270202,0.00009274305,0.00007366446,0.0001495264,0.00001025162,0.0002670711,0.000002004752],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979593,0.0006872721,0.00004967226,0.0001327268,0.000009065863,0.000006242695,0.00040723,0.000003726738,0.0007447699],"genre_scores_gemma":[0.9990298,0.0002214416,0.00008370123,0.00004845341,0.00001071662,0.000004778359,0.0005276826,0.000002368714,0.00007112328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01171569,"threshold_uncertainty_score":0.02329499,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}