{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":1480,"total_is_capped":false,"direct_labels_cover":1,"predictions_cover":1480,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"e058f8d1ff42","filters":{"topic":"Nuclear Structure and Function"}},"results":[{"id":"W2133201628","doi":"10.1083/jcb.148.4.635","title":"The Yeast Nuclear Pore Complex","year":2000,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1405,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Center for Research Resources","keywords":"Nucleoporin; Nuclear pore; Nuclear transport; Yeast; Component (thermodynamics); Cell biology; Computational biology; Biology; Chemistry; Cytoplasm; Cell nucleus; Genetics; Physics","retraction":null,"screen_n_in":null,"score":{"opus":0.006358089417302744,"gpt":0.211326888771617,"spread":0.2049687993543143,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002210843,0.00006267892,0.00007472766,0.000009232626,0.0001482828,0.000009462829,0.0002518556,0.00007190379,0.0003259024],"category_scores_gemma":[0.00001111316,0.0000296637,0.00006787728,0.00002888073,0.0001388208,0.000001418773,0.00002611685,0.0001197954,0.00003368794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004349919,"about_ca_system_score_gemma":0.00001744599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000348736,"about_ca_topic_score_gemma":0.000003818998,"domain_scores_codex":[0.9995212,0.0001115703,0.0001541469,0.00005164214,0.00004316166,0.0001182759],"domain_scores_gemma":[0.9996321,0.00001451609,0.0001072225,0.0001660335,0.0000503677,0.00002971479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003868515,0.00001001117,0.00003768824,0.000001014787,0.00003095745,0.000001150418,0.00004820957,0.00002094314,0.9598444,0.0001032771,0.01151269,0.02800284],"study_design_scores_gemma":[0.0002504481,0.0004980441,0.001338032,0.00000124853,0.00002118406,0.000187606,0.00008954001,0.00001582948,0.01910062,0.0004942366,0.9779552,0.00004798438],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984107,0.0005203324,0.00002652969,0.0005898608,0.0002150669,0.00003412182,0.000002760078,0.000002202616,0.01450217],"genre_scores_gemma":[0.9969156,0.001061642,0.00007432146,0.000599601,0.0004796538,1.204783e-7,0.000005927009,0.000009013072,0.000854136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9664425,"threshold_uncertainty_score":0.3568402,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2163504716","doi":"10.1083/jcb.200509124","title":"Coupling of the nucleus and cytoplasm: Role of the LINC complex","year":2005,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1359,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Cytoplasm; Inner membrane; Biology; Nucleus; Endoplasmic reticulum; Cell biology; Cytoskeleton; Nuclear pore; Membrane protein; Biophysics; Coupling (piping); Membrane; Cell; Biochemistry; Materials science","retraction":null,"screen_n_in":null,"score":{"opus":0.005425441878660534,"gpt":0.2042863731157553,"spread":0.1988609312370947,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002024153,0.00005714813,0.0001097572,0.00001108007,0.00005820807,0.000002072683,0.0002351952,0.00007922069,0.00001710937],"category_scores_gemma":[0.00002405079,0.00002485324,0.00007458777,0.00003502645,0.0001921485,0.000001589161,0.0001014576,0.000114785,5.125177e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004067892,"about_ca_system_score_gemma":0.00002732295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006591389,"about_ca_topic_score_gemma":0.00001361109,"domain_scores_codex":[0.9995776,0.00005094005,0.0002004734,0.00004684802,0.00004908762,0.00007503827],"domain_scores_gemma":[0.9994053,0.00002443166,0.0003095199,0.0001718996,0.00007365287,0.00001525135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001044296,0.00001184359,0.001488748,0.000003731947,0.00002505073,3.082909e-8,0.00007770445,0.0003149274,0.996583,0.00007830601,0.0001543298,0.001157918],"study_design_scores_gemma":[0.000334111,0.0002579399,0.01148484,0.000006789554,0.00005044252,0.00005961705,0.0001533199,0.000268192,0.9392065,0.0002864829,0.04785343,0.00003829874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979546,0.0007863235,0.00003189276,0.0003059496,0.0001378922,0.00004338439,0.000005617857,5.710129e-7,0.0007337775],"genre_scores_gemma":[0.9991589,0.0002782012,0.0001403364,0.0001586844,0.0001962236,9.626782e-8,7.425008e-7,0.000005230054,0.00006163836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05737644,"threshold_uncertainty_score":0.1013486,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136295423","doi":"10.1093/aob/mcq243","title":"Proliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulation","year":2010,"lang":"en","type":"review","venue":"Annals of Botany","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":794,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Lethbridge","funders":"University of Lethbridge","keywords":"Proliferating cell nuclear antigen; Biology; Replication factor C; DNA replication; DNA polymerase delta; DNA clamp; DNA polymerase; Eukaryotic DNA replication; DNA repair; Cell biology; Cell cycle; Genetics; DNA; Gene; Reverse transcriptase","retraction":null,"screen_n_in":null,"score":{"opus":0.02719812639232998,"gpt":0.2986604772848399,"spread":0.2714623508925099,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169199,0.0002012452,0.0004138121,0.00006744196,0.00004773784,0.00002551801,0.0001134236,0.0004696089,0.00002657693],"category_scores_gemma":[0.00004822018,0.0001851236,0.0001322563,0.00009132072,0.0000370874,0.000007907778,0.00006518392,0.0001923734,0.00001163936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004738825,"about_ca_system_score_gemma":0.00004611106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001032821,"about_ca_topic_score_gemma":0.00001076557,"domain_scores_codex":[0.9988543,0.0000666359,0.0003840581,0.0004416654,0.00009481413,0.0001585244],"domain_scores_gemma":[0.9989793,0.000009801936,0.0003732546,0.0005152657,0.00007250554,0.00004989309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004048295,0.00007945289,0.0001088137,0.002564115,0.00003457959,0.000001355747,0.000129167,8.862613e-7,0.2610875,0.00003941202,0.001288329,0.7346259],"study_design_scores_gemma":[0.0001184424,0.0001373542,0.0007337829,0.0003286692,0.00002894195,0.000007573632,0.000008780092,0.0000197861,0.01206967,0.00004278076,0.9862928,0.0002113962],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2378947,0.7592815,0.00001749229,0.00003832993,0.0001203835,0.0006033509,0.00004759933,0.00001375656,0.00198291],"genre_scores_gemma":[0.05344754,0.9454054,0.0004564392,0.00006098687,0.0002226434,0.00001031573,0.0001057472,0.00005276905,0.0002381048],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9850045,"threshold_uncertainty_score":0.754912,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029208937","doi":"10.1091/mbc.01-06-0308","title":"Nuclear Pore Complex Is Able to Transport Macromolecules with Diameters of ∼39 nm","year":2002,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":773,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Deutsche Forschungsgemeinschaft","keywords":"Nuclear pore; Cytoplasm; Macromolecule; Nuclear transport; Cytosol; Biophysics; Nucleoporin; Nucleus; Receptor; Biology; Cell nucleus; Nuclear localization sequence; Macromolecular Substances; Cell biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.006639881713515006,"gpt":0.1921705598445637,"spread":0.1855306781310487,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005176548,0.0001560141,0.0002017822,0.00004006023,0.0000471881,0.000002778097,0.0003172544,0.0001490046,0.0001520966],"category_scores_gemma":[0.000007323634,0.0001104775,0.0001522355,0.0001228533,0.00021473,0.000001563625,0.00007216788,0.00007460861,0.000007932405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005347457,"about_ca_system_score_gemma":0.000009688776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003121005,"about_ca_topic_score_gemma":0.000006405156,"domain_scores_codex":[0.9991824,0.00005277425,0.0001903935,0.0002874694,0.00008846486,0.0001984851],"domain_scores_gemma":[0.9992632,0.00000359633,0.0001175595,0.0005015747,0.00005937419,0.00005471129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000898546,0.00004844821,0.001484462,0.00002347916,0.00006843795,0.000003127628,0.0001027412,0.00006164858,0.9959518,0.00009655012,0.001637305,0.000432121],"study_design_scores_gemma":[0.0004085751,0.0007266386,0.001686518,0.00001060241,0.00005108549,0.00001724492,0.00005209796,0.00002683255,0.9704092,0.00008311374,0.02637526,0.0001528383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937456,0.0002138097,0.001385432,0.0005023941,0.00007701576,0.0001913671,0.00004570019,0.000007012199,0.003831679],"genre_scores_gemma":[0.9948942,0.00002581608,0.003033511,0.001575268,0.00002058845,0.00000282892,0.00003695292,0.00003015896,0.0003806407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02554264,"threshold_uncertainty_score":0.4505142,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2111607030","doi":"10.1186/1471-2105-10-202","title":"NLStradamus: a simple Hidden Markov Model for nuclear localization signal prediction","year":2009,"lang":"en","type":"article","venue":"BMC Bioinformatics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":719,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Nuclear localization sequence; NLS; Hidden Markov model; Nuclear transport; Markov chain; Computational biology; Simple (philosophy); Computer science; Set (abstract data type); Markov model; Artificial intelligence; Biology; Machine learning; Genetics; Cell nucleus; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01034064885787714,"gpt":0.2196102180540038,"spread":0.2092695691961267,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008165409,0.0001213351,0.00009190753,0.00003839135,0.0001296215,0.00004304642,0.00009594805,0.0001767636,0.00001942086],"category_scores_gemma":[0.000025401,0.0001146512,0.00008266368,0.00005727396,0.00002279919,0.00001854944,0.00002033716,0.00004816871,0.000008588839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001657183,"about_ca_system_score_gemma":0.00003800949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.882262e-7,"about_ca_topic_score_gemma":0.000003858069,"domain_scores_codex":[0.9993367,0.000008112066,0.0002495621,0.0001242989,0.0001076448,0.0001736449],"domain_scores_gemma":[0.999579,0.000003961866,0.00009477082,0.000193809,0.00007029054,0.00005815989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.002598208,0.0003507094,0.001155102,0.0006926798,0.0002121502,7.429394e-7,0.002192993,0.1279342,0.06004418,0.006468222,0.3532727,0.4450782],"study_design_scores_gemma":[0.0005257229,0.0004170691,0.0003963802,0.000006337794,0.00002838573,0.000009579596,0.0001119004,0.9812803,0.0008518189,0.0007320359,0.01550229,0.0001381691],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.02341065,0.00002708068,0.9742236,0.00004301744,0.0000977616,0.0003253476,0.00008895742,0.00005539286,0.001728248],"genre_scores_gemma":[0.7820001,0.00004057433,0.2141764,0.001534693,0.0004325156,0.00000774197,0.001449674,0.00003497381,0.0003233043],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.8533461,"threshold_uncertainty_score":0.467534,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2139706576","doi":"10.1093/hmg/9.1.109","title":"Nuclear lamin A/C R482Q mutation in Canadian kindreds with Dunnigan-type familial partial lipodystrophy","year":2000,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":657,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"LMNA; Biology; Lamin; Genetics; Missense mutation; Progeria; Mutation; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.004090976467654862,"gpt":0.2053384829984289,"spread":0.201247506530774,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005396885,0.0001970814,0.0001339297,0.00009310806,0.0001218598,0.00004465257,0.0001577777,0.0002149639,0.000290523],"category_scores_gemma":[0.000007277665,0.000207115,0.00005133659,0.0001594606,0.00008620004,0.00000410664,0.00001978689,0.0001416347,0.00005732012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004252281,"about_ca_system_score_gemma":0.0001198008,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004981035,"about_ca_topic_score_gemma":0.03481481,"domain_scores_codex":[0.9987904,0.00005805731,0.0001934564,0.0003882353,0.0001653603,0.0004044452],"domain_scores_gemma":[0.9993611,0.000001350751,0.00003951277,0.0003574288,0.00005791757,0.0001826745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003266872,0.00006947672,0.003437783,0.00001590964,0.00008133927,0.0003462221,0.0003064481,0.004654383,0.9787211,0.0004071568,0.001280686,0.01035275],"study_design_scores_gemma":[0.004789528,0.005183512,0.1737311,0.00006540275,0.0001975741,0.0003440836,0.0002511261,0.001883252,0.1798308,0.0004848766,0.6312972,0.001941571],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964362,0.0002102266,0.00003935109,0.00005034474,0.0001173459,0.0001895869,0.000008811756,0.00001494106,0.002933198],"genre_scores_gemma":[0.9979723,0.00004178865,0.0006223741,0.0004502614,0.0002218586,0.000004803345,0.0002278347,0.00006324901,0.0003955489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7988904,"threshold_uncertainty_score":0.9827973,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2111073993","doi":"10.1186/1756-0500-3-294","title":"REAP: A two minute cell fractionation method","year":2010,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":528,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Cytoplasm; Cell fractionation; Centrifugation; Nucleus; Cell biology; Differential centrifugation; Nuclear export signal; Biophysics; Cell nucleus; Biology; Chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.07073439761839513,"gpt":0.4282599988773246,"spread":0.3575256012589295,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007748072,0.0000726041,0.00005944958,0.00008294451,0.0001486981,0.00004479962,0.0001316498,0.0001334491,0.0001790953],"category_scores_gemma":[0.00067825,0.00006491699,0.0000510236,0.0001288721,0.00005949016,0.000006088195,0.00008110468,0.0003224012,0.00009536014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007786824,"about_ca_system_score_gemma":0.00008590907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001809111,"about_ca_topic_score_gemma":0.0004227677,"domain_scores_codex":[0.9990092,0.0001494251,0.00009303901,0.000272634,0.0002587039,0.000216978],"domain_scores_gemma":[0.9992182,0.0001289272,0.00002908136,0.000317099,0.0002346357,0.00007206496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007398005,0.00002334746,0.001912951,0.000009013239,0.000006185047,7.354813e-7,0.00001886327,0.00001303667,0.9823886,0.0003375674,0.003707106,0.01150864],"study_design_scores_gemma":[0.0003943357,0.0001531477,0.01021777,0.000002135458,0.000004858819,0.0000131391,0.00004100964,0.0003682114,0.7652268,0.001849923,0.2216211,0.0001075383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9582429,0.0001160655,0.02666967,0.0004402389,0.0005883368,0.0002466752,0.00001037114,0.00002428477,0.01366145],"genre_scores_gemma":[0.9462258,0.00002814784,0.05021501,0.00006706313,0.001064025,0.00001898429,0.00007786988,0.00001976292,0.002283371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.217914,"threshold_uncertainty_score":0.2647238,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2220896177","doi":"10.1038/nature15381","title":"In situ structural analysis of the human nuclear pore complex","year":2015,"lang":"en","type":"article","venue":"Nature","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":447,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute on Aging","keywords":"Nucleoporin; Nuclear pore; In situ; Nuclear transport; Scaffold protein; Biophysics; Structural biology; Chemistry; Inner membrane; Nucleus; Crystallography; Biology; Cell biology; Membrane; Cell nucleus; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01012066451864074,"gpt":0.2685866231603171,"spread":0.2584659586416763,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004626608,0.00006038831,0.000097623,0.00004572493,0.00002830888,0.000005773033,0.0001426391,0.0004094599,0.00003936924],"category_scores_gemma":[0.00002244458,0.00004073415,0.00008675682,0.0002564952,0.00003832108,0.00000213917,0.00006170865,0.0003219193,7.241102e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000935531,"about_ca_system_score_gemma":0.00001098413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002038354,"about_ca_topic_score_gemma":0.0001999208,"domain_scores_codex":[0.9995899,0.00002623123,0.00008498589,0.0001228336,0.0001016933,0.00007438644],"domain_scores_gemma":[0.9996451,0.00000124263,0.00004888859,0.0002292086,0.00005116023,0.00002446343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004475577,0.000009401658,0.01715644,0.000004306626,0.0001830623,0.000001605979,0.0001694019,0.0001472134,0.9606021,0.001388219,0.0200745,0.0002189927],"study_design_scores_gemma":[0.0006009825,0.0000894711,0.8777224,0.000003586101,0.0002020922,0.000008608638,0.0002721066,0.0001769958,0.02313745,0.0006965356,0.09693258,0.0001572116],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963152,0.0001000852,0.00000108139,0.0002124608,0.0001280073,0.00004115279,0.00001008186,0.000002861867,0.003189056],"genre_scores_gemma":[0.9987673,0.000001178332,0.00008226404,0.0007799424,0.00009637789,2.679739e-7,0.00009535503,0.000006770358,0.0001705683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9374647,"threshold_uncertainty_score":0.315813,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012502527","doi":"10.1038/nrm879","title":"Life at the edge: the nuclear envelope and human disease","year":2002,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":423,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Lamin; Nuclear lamina; Biology; Envelope (radar); Housekeeping gene; Gene; Genetics; Nuclear protein; Nucleus; Cell biology; Computational biology; Gene expression; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.01475756050491338,"gpt":0.2818952250427664,"spread":0.267137664537853,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003989402,0.0006502659,0.001066356,0.00005198366,0.0004393285,0.00005005477,0.0007151546,0.001327677,0.0002276985],"category_scores_gemma":[0.0003050593,0.0003181707,0.0007897901,0.000188401,0.0003769469,0.000002467457,0.0006410796,0.001163265,0.0002072848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003206414,"about_ca_system_score_gemma":0.0000863015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002841848,"about_ca_topic_score_gemma":0.000004572618,"domain_scores_codex":[0.9970172,0.0009953724,0.0005727015,0.000900254,0.0001179233,0.0003965453],"domain_scores_gemma":[0.9978166,0.00003700796,0.0004777521,0.001366539,0.00004804038,0.0002540713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001937107,0.00003439106,0.000007319794,0.003713598,0.0002463117,0.00001719555,0.0000129787,2.055181e-7,0.002372672,0.001020605,0.09029238,0.902263],"study_design_scores_gemma":[0.0001207821,0.00009477737,0.000004661454,0.0003335002,0.000772742,0.00003644747,0.000002008993,3.713118e-7,0.00002085926,0.00003192356,0.998198,0.0003839086],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006070839,0.9939421,0.00001015923,0.0003033741,0.0004484389,0.001342432,0.00004699175,0.00001506365,0.003830774],"genre_scores_gemma":[0.0001945738,0.9928969,0.00004758984,0.003852362,0.0006374772,0.00008907683,0.0006833146,0.0001028977,0.001495826],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9079056,"threshold_uncertainty_score":0.9999688,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2113656016","doi":"10.1111/j.1365-313x.2009.04048.x","title":"Arabidopsis homolog of the yeast TREX-2 mRNA export complex: components and anchoring nucleoporin","year":2009,"lang":"en","type":"article","venue":"The Plant Journal","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":409,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University; Plant Biotechnology Institute; University of Guelph; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; Genome Prairie; RIKEN; Genome Canada","keywords":"Nucleoporin; Arabidopsis; Nuclear pore; Biology; Arabidopsis thaliana; Yeast; Karyopherin; Genetics; Saccharomyces cerevisiae; Gene; Cell biology; Computational biology; Nuclear transport; Cytoplasm; Mutant; Cell nucleus","retraction":null,"screen_n_in":null,"score":{"opus":0.01995734855481509,"gpt":0.2178763552043318,"spread":0.1979190066495167,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000125008,0.00007059838,0.00008445233,0.00001454386,0.0001574746,0.00001707071,0.0001486291,0.00004134939,0.00001770087],"category_scores_gemma":[0.000009503351,0.00003873226,0.00005349766,0.00003115183,0.00005564856,0.000002853562,0.00003755335,0.0001293732,0.000001097636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004729035,"about_ca_system_score_gemma":0.00001070133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004417224,"about_ca_topic_score_gemma":0.000002817493,"domain_scores_codex":[0.9995469,0.0000398699,0.0001299152,0.00007918388,0.0000947973,0.0001093082],"domain_scores_gemma":[0.9996842,0.000004068101,0.0001094332,0.0001461909,0.00002089214,0.00003524303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001225564,0.00002561411,0.00829075,0.000002953804,0.00004814463,0.000005475576,0.0001313006,0.00002222885,0.9789371,0.0001129532,0.004889975,0.007410938],"study_design_scores_gemma":[0.0006800782,0.0003148339,0.9176513,0.00003287217,0.00005559858,0.002531291,0.000154452,0.00009027767,0.04427462,0.001094323,0.03297745,0.0001429299],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981145,0.0001496376,0.00005639573,0.0003929029,0.0002122257,0.00004409976,0.00001578641,0.000002576892,0.001011847],"genre_scores_gemma":[0.9991019,0.0001512457,0.000111622,0.0002032446,0.000344833,2.31278e-7,0.000008479051,0.000004776952,0.00007364182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9346625,"threshold_uncertainty_score":0.1579456,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1995958002","doi":"10.1038/ng1145","title":"Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders","year":2003,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":387,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"COPII; Vesicle; Biology; Cell biology; Chylomicron; Intracellular; GTPase; Intracellular transport; COPI; Biogenesis; Transport protein; Vesicular transport protein; GTPase-activating protein; Biochemistry; Secretory pathway; Membrane; G protein; Signal transduction; Cholesterol; Gene; Golgi apparatus; Endoplasmic reticulum; Lipoprotein","retraction":null,"screen_n_in":null,"score":{"opus":0.00383106516536871,"gpt":0.2143988237202362,"spread":0.2105677585548675,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006256917,0.00009638334,0.00009605964,0.00004759131,0.00003086744,0.000006768737,0.00005588969,0.0002917487,0.00001187893],"category_scores_gemma":[0.0001092488,0.00008716923,0.00003356415,0.0001672271,0.00004854093,0.00000211335,0.0000105941,0.0001598147,0.000001148627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001277791,"about_ca_system_score_gemma":0.00003829874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002943753,"about_ca_topic_score_gemma":0.0005636957,"domain_scores_codex":[0.9994311,0.00004551565,0.0001230817,0.0001753632,0.0001031704,0.0001217166],"domain_scores_gemma":[0.99963,0.000008544935,0.00009862445,0.0001591911,0.00007497593,0.00002866189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003444588,0.0004732026,0.4358031,0.00007344867,0.0002241859,0.000006293998,0.0003881429,0.004036108,0.5470084,0.000626001,0.003217744,0.00779886],"study_design_scores_gemma":[0.002545747,0.0007230495,0.7506762,0.00007174479,0.00008811301,0.00001007646,0.0004459481,0.0001554096,0.2128342,0.001098512,0.03090708,0.0004439822],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980374,0.0008456128,0.0001820534,0.00005492988,0.0001352034,0.0001205922,0.00001961113,0.000006409162,0.0005981855],"genre_scores_gemma":[0.9986866,0.0001405045,0.0007891036,0.0001215543,0.00004655355,0.000004524697,0.0001097856,0.00001714664,0.00008427667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3341742,"threshold_uncertainty_score":0.3554658,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2158799849","doi":"10.1016/s0092-8674(01)00628-6","title":"Cytoplasmic Dynein as a Facilitator of Nuclear Envelope Breakdown","year":2002,"lang":"en","type":"article","venue":"Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":378,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences","keywords":"Prometaphase; Biology; Dynein; Cell biology; Dynactin; Prophase; Inner membrane; Nuclear membrane; Nuclear pore; Nuclear lamina; Dynein ATPase; Microtubule; Biophysics; Cytoplasm; Nuclear protein; Genetics; Meiosis; Mitochondrion","retraction":null,"screen_n_in":null,"score":{"opus":0.005054795057127939,"gpt":0.1789679532941216,"spread":0.1739131582369937,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003068995,0.00007831372,0.00007900297,0.00001971375,0.0000317788,0.000006137641,0.00008497758,0.00009684559,0.0009335733],"category_scores_gemma":[0.00001838087,0.00007349061,0.0000521397,0.00005059978,0.00004295796,0.000001920425,0.00003667674,0.00004822588,0.0004033297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005226848,"about_ca_system_score_gemma":0.000009254631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001365017,"about_ca_topic_score_gemma":0.000002722059,"domain_scores_codex":[0.9995354,0.00001546243,0.0001007658,0.0001641206,0.0000611867,0.0001230728],"domain_scores_gemma":[0.9996779,0.000002978793,0.00003694183,0.0002001483,0.00003477372,0.00004725317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000357263,0.00003191364,0.0001763131,0.0000190649,0.00001254297,0.000001980069,0.0001289123,0.000004564793,0.9723133,0.00005747191,0.02462945,0.002588759],"study_design_scores_gemma":[0.0004069528,0.0003538044,0.001014498,0.000003993232,0.00001200307,0.00001701833,0.0001071196,0.00005555211,0.3101335,0.00005236395,0.6877074,0.0001357817],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9497752,0.0002619697,0.00002684157,0.00005945528,0.0001219492,0.00005498613,0.00001149379,0.000009629034,0.04967844],"genre_scores_gemma":[0.993727,0.0001052821,0.000307591,0.0002484115,0.00007085348,0.000001102265,0.00001644373,0.00001419328,0.005509087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.663078,"threshold_uncertainty_score":0.9999797,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2145893833","doi":"10.1074/jbc.275.7.4840","title":"MAN1, an Inner Nuclear Membrane Protein That Shares the LEM Domain with Lamina-associated Polypeptide 2 and Emerin","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":337,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University; Ottawa Regional Cancer Foundation; University of Ottawa","funders":"National Cancer Institute; American Liver Foundation; National Institutes of Health; Medical Research Council Canada; National Center for Research Resources; Centre National de la Recherche Scientifique; Medical Research Council","keywords":"Emerin; Nuclear lamina; Inner membrane; Biology; Integral membrane protein; Nucleoporin; Nuclear pore; Membrane protein; Nuclear protein; Molecular biology; Nuclear localization sequence; Cell biology; Cytoplasm; Cell nucleus; Genetics; Gene; Nuclear transport; Membrane; Mitochondrion","retraction":null,"screen_n_in":null,"score":{"opus":0.008535789965267996,"gpt":0.2009891785252689,"spread":0.1924533885600009,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001867418,0.0001417133,0.0001640741,0.000007998073,0.0001007557,0.000038413,0.000185568,0.0002089065,0.0005590938],"category_scores_gemma":[0.00003108047,0.00007348361,0.0000657685,0.0000498486,0.0001595909,0.000008722016,0.00003563804,0.0002245042,0.000001764181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001086286,"about_ca_system_score_gemma":0.00001699246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005152386,"about_ca_topic_score_gemma":0.000003669018,"domain_scores_codex":[0.9992911,0.00005930091,0.0001801081,0.0001792895,0.0001218995,0.0001683061],"domain_scores_gemma":[0.9995419,0.00000803975,0.0001550576,0.0001574858,0.00004911501,0.00008837553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006468032,0.00005255396,0.001118352,0.000008757134,0.00006813075,0.00002053923,0.00003070543,0.000004764001,0.9946682,0.000006359735,0.000352875,0.003021996],"study_design_scores_gemma":[0.002159985,0.003035377,0.03616896,0.00008988366,0.00006880268,0.001118354,0.0009357747,0.00001806605,0.8422079,0.0003406064,0.1133328,0.0005234787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981863,0.0002238693,0.000005957726,0.0003404218,0.00001521281,0.00006732706,0.000009857527,0.000007766355,0.00114331],"genre_scores_gemma":[0.99843,0.0001557749,0.000309267,0.0002699062,0.0002500342,0.000001834669,0.0000236456,0.00001380218,0.0005457481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1524602,"threshold_uncertainty_score":0.6121685,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2335825911","doi":"10.1126/science.aaf0643","title":"Molecular architecture of the inner ring scaffold of the human nuclear pore complex","year":2016,"lang":"en","type":"article","venue":"Science","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":331,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"H2020 European Research Council; National Institute on Aging; Stevens Institute of Technology; European Molecular Biology Laboratory","keywords":"Nuclear pore; Nucleus; Cytoplasm; Macromolecule; Ring (chemistry); Inner membrane; Biophysics; Nucleoporin; Chemistry; Crystallography; Materials science; Cell nucleus; Membrane; Nuclear transport; Cell biology; Biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.007293110418973875,"gpt":0.2227766220520483,"spread":0.2154835116330744,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001035671,0.00004986237,0.00004800057,0.00001613791,0.0001222612,0.000005516682,0.0004617828,0.00003208485,0.00001792554],"category_scores_gemma":[0.00004296962,0.0000216725,0.00005718725,0.0001599672,0.0006820633,0.000002487774,0.0002423993,0.0000322068,6.651804e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005098593,"about_ca_system_score_gemma":0.00002884589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005418719,"about_ca_topic_score_gemma":0.000005408661,"domain_scores_codex":[0.999481,0.00002004747,0.00008107646,0.0001458633,0.0001686293,0.0001033336],"domain_scores_gemma":[0.9994503,0.000002098596,0.00007277914,0.0004048785,0.00005143185,0.00001851476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003470925,0.000004097757,0.001301604,0.000003169121,0.000002950695,7.161003e-8,0.00003760025,0.00001913372,0.9956291,0.001382829,0.00007898125,0.001537015],"study_design_scores_gemma":[0.0001085657,0.00004169858,0.07572417,0.00001855258,0.000004735215,0.000005970814,0.000023153,0.0000058599,0.9159719,0.0006433938,0.007407484,0.00004453543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971628,0.00001849093,0.00008103849,0.000335087,0.0001088139,0.00005753258,0.000004073849,0.00000239779,0.00222981],"genre_scores_gemma":[0.999575,0.000001229133,0.0001186377,0.0001750457,0.00002880991,3.658633e-7,3.45378e-7,0.000005281308,0.00009527203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0796572,"threshold_uncertainty_score":0.2513091,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124633704","doi":"10.1074/jbc.m112.441535","title":"Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":325,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"David Geffen School of Medicine, University of California, Los Angeles; Division of Materials Research; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; UCLA AIDS Institute; National Institute of Neurological Disorders and Stroke; Materials Research Science and Engineering Center, Harvard University; Center for AIDS Research, University of Washington; Jonsson Comprehensive Cancer Center; National Science Foundation; American Heart Association; National Heart, Lung, and Blood Institute; U.S. Department of Defense; National Cancer Institute; National Institutes of Health; Harvard University","keywords":"Lamin; Granulopoiesis; Nucleus; Cell biology; Biology; Neutrophil extracellular traps; Envelope (radar); Haematopoiesis; Chemistry; Stem cell; Immunology","retraction":null,"screen_n_in":null,"score":{"opus":0.01029494895405688,"gpt":0.2196609125195243,"spread":0.2093659635654674,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009443808,0.0001119546,0.0001760036,0.000008954416,0.00007456546,0.00001832764,0.0002056811,0.0001855135,0.000213062],"category_scores_gemma":[0.00004211376,0.00006676789,0.0001363115,0.00008731137,0.0001670271,0.000007200882,0.00007887537,0.0001631999,0.00001026131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001463215,"about_ca_system_score_gemma":0.00002352104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006487573,"about_ca_topic_score_gemma":2.22273e-7,"domain_scores_codex":[0.9992652,0.00004427773,0.0003308383,0.0001461454,0.00008535807,0.000128183],"domain_scores_gemma":[0.9992542,0.00002632295,0.0002177404,0.0001925461,0.0002411492,0.00006806046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001035409,0.00005448409,0.000985791,0.00001092011,0.00002736074,0.000001014763,0.00002371997,0.00001889998,0.99428,0.000003301276,0.003839312,0.0006516685],"study_design_scores_gemma":[0.0002061903,0.0004132821,0.0132202,0.00001097159,0.00002053651,0.0001103374,0.0001257581,0.000003681081,0.9694108,0.0001309051,0.0162521,0.00009521324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998262,0.0001144369,0.0001524422,0.0004827033,0.0001799045,0.00009541123,0.00001028439,0.000004412275,0.0006983364],"genre_scores_gemma":[0.9974943,0.0001439073,0.001650253,0.0003356599,0.0003270304,0.000001490262,0.00001022477,0.000007266079,0.00002985968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02486916,"threshold_uncertainty_score":0.2722716,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2261310019","doi":"10.1038/ncomms9044","title":"Loss of lamin A function increases chromatin dynamics in the nuclear interior","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":309,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Canadian Institutes of Health Research; Austrian Science Fund; National Institute of General Medical Sciences; Bar-Ilan University; U.S. Department of Defense","keywords":"Chromatin; Lamin; Biology; Nuclear lamina; Cell biology; Nucleus; Genome; Cell nucleus; Dynamics (music); Inner membrane; Scaffold/matrix attachment region; Genomic organization; Chromatin remodeling; Genetics; Nuclear protein; Gene; Transcription factor; Physics","retraction":null,"screen_n_in":null,"score":{"opus":0.01069848183300025,"gpt":0.2606969329549569,"spread":0.2499984511219567,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001880708,0.00006090633,0.00006659083,0.00003552973,0.00004805612,0.00001156746,0.0004625657,0.0001710074,0.000005078794],"category_scores_gemma":[0.0001536996,0.00004678507,0.00003598219,0.0001352134,0.00009277077,0.000004763048,0.0001563819,0.0002519082,0.000004420961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002565388,"about_ca_system_score_gemma":0.00002878017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007285603,"about_ca_topic_score_gemma":0.001590373,"domain_scores_codex":[0.9995208,0.0001277952,0.0001249698,0.00008594659,0.00007714279,0.00006336684],"domain_scores_gemma":[0.9989747,0.00002134107,0.0000664196,0.0008360474,0.00008187906,0.00001963734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002388861,0.002141198,0.1617001,0.0001591979,0.0005372233,0.00001227207,0.005323747,0.0001023576,0.3132738,0.2821473,0.1862397,0.04597434],"study_design_scores_gemma":[0.002352797,0.001415071,0.1353539,0.00009334377,0.0001455822,0.0002060132,0.01066945,0.005747908,0.00207772,0.002597253,0.8387962,0.0005448019],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899513,0.001256553,0.00008589413,0.001502034,0.0001139567,0.0001454178,0.00002209401,0.00001105833,0.006911755],"genre_scores_gemma":[0.9981447,0.0001022964,0.0009032717,0.0005212587,0.00004635605,0.000007277137,0.0002304305,0.000009470799,0.00003492738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6525565,"threshold_uncertainty_score":0.190784,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2066834513","doi":"10.1038/nrm2894","title":"The nuclear envelope in genome organization, expression and stability","year":2010,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":286,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Genome; Inner membrane; Biology; Genomic organization; Nuclear pore; Genetics; Computational biology; Cell biology; Nucleus; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.007626985008499434,"gpt":0.2565570306227205,"spread":0.2489300456142211,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006151478,0.0004505901,0.0009221299,0.00006775262,0.000161325,0.00004211594,0.0004536709,0.002487857,0.00004547271],"category_scores_gemma":[0.0004540254,0.0002738659,0.0002246247,0.0002924392,0.0001701888,0.000003332609,0.0003346371,0.001506979,0.00003167243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002771424,"about_ca_system_score_gemma":0.0001160081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000019969,"about_ca_topic_score_gemma":0.00001210194,"domain_scores_codex":[0.9975354,0.0006734194,0.0006143692,0.0007802485,0.00008209208,0.0003144646],"domain_scores_gemma":[0.9985428,0.00003414312,0.000382974,0.0008558685,0.00009913181,0.00008509015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001094844,0.0000261404,0.0000301057,0.002008597,0.00002721778,0.000004622894,0.0000158777,4.680349e-8,0.1587824,0.0002412063,0.0003739992,0.8384789],"study_design_scores_gemma":[0.0001150486,0.00006213387,0.00001065417,0.0002355632,0.00008360785,0.00002344344,0.000003424035,1.209104e-7,0.0007925141,0.00003627891,0.9983435,0.0002936765],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004695499,0.9972493,0.00004131064,0.00002862482,0.0004055631,0.0009902061,0.00001741709,0.00001119341,0.0007868559],"genre_scores_gemma":[0.000430017,0.997793,0.0005376272,0.0002394304,0.0002015012,0.00003120835,0.0006434236,0.00007970847,0.00004410954],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9979695,"threshold_uncertainty_score":0.9999713,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2084711835","doi":"10.1074/jbc.r100015200","title":"The Nuclear Pore Complex as a Transport Machine","year":2001,"lang":"en","type":"review","venue":"Journal of Biological Chemistry","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":274,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoporin; Nuclear pore; Nuclear transport; Cytoplasm; Ribonucleoprotein; Cell biology; Ran; Nucleus; Chemistry; Cell nucleus; Biology; Biophysics; RNA; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03502392545581943,"gpt":0.2932171394056743,"spread":0.2581932139498548,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002598788,0.0003183227,0.0007513933,0.00001535246,0.0001387416,0.00002726632,0.0005611141,0.0006984299,0.0002997883],"category_scores_gemma":[0.0001056813,0.0001598644,0.0008795179,0.0001033047,0.0001762352,0.000002000747,0.00007122548,0.0006095212,0.00001253371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002801701,"about_ca_system_score_gemma":0.000104694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001357158,"about_ca_topic_score_gemma":4.555088e-7,"domain_scores_codex":[0.998602,0.00006525018,0.000677742,0.000247669,0.0001682379,0.0002390617],"domain_scores_gemma":[0.9987442,0.0000317164,0.0006855212,0.000303665,0.00009812877,0.0001367312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004004753,0.0001182376,0.00003811409,0.001202731,0.0007855383,0.0003021036,0.000008739064,9.139312e-7,0.01266546,0.00003959689,0.01135756,0.9730805],"study_design_scores_gemma":[0.000169643,0.0002823413,0.00001708695,0.0002614808,0.0001805431,0.003411533,0.00001891995,3.002995e-7,0.0001032666,0.00005585305,0.9953038,0.0001952368],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001230786,0.9918793,0.000008377689,0.00006281886,0.0001857404,0.0001003425,0.000029733,0.000007735459,0.006495142],"genre_scores_gemma":[0.001707519,0.995665,0.00007937456,0.0001089989,0.001300894,0.000001942844,0.0002468879,0.00003296947,0.0008564102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9839463,"threshold_uncertainty_score":0.651908,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2115851807","doi":"10.1105/tpc.108.064519","title":"Nuclear Pore Complex Component MOS7/Nup88 Is Required for Innate Immunity and Nuclear Accumulation of Defense Regulators in<i>Arabidopsis</i>   ","year":2009,"lang":"en","type":"article","venue":"The Plant Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":264,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Brock University; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; Alexander von Humboldt-Stiftung; University of British Columbia; Arizona Biomedical Research Commission; Deutsche Forschungsgemeinschaft; International Max Planck Research School for Environmental, Cellular and Molecular Microbiology","keywords":"Biology; Nucleoporin; Nuclear pore; Cell biology; Arabidopsis; Nuclear localization sequence; Nuclear protein; Arabidopsis thaliana; Nuclear export signal; Innate immune system; Drosophila melanogaster; Nuclear transport; Mutant; Transcription factor; Genetics; Cell nucleus; Nucleus; Immune system; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.03057601533602128,"gpt":0.2470842149579965,"spread":0.2165081996219752,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000145245,0.0001120268,0.0001410132,0.0000324963,0.00009779171,0.00001354524,0.000145613,0.0001086883,0.00001222013],"category_scores_gemma":[0.000009547803,0.00008928274,0.00006441218,0.00005443965,0.00007104992,0.000005716628,0.00006324006,0.0000759568,0.000001793294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008692718,"about_ca_system_score_gemma":0.000007707841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003135429,"about_ca_topic_score_gemma":0.000008421058,"domain_scores_codex":[0.9993806,0.00004139685,0.0001914546,0.0001696626,0.00007495863,0.000141968],"domain_scores_gemma":[0.999488,0.00001467003,0.000112297,0.0003237419,0.00002894872,0.00003231966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007955407,0.00005399513,0.0002279642,0.00002684047,0.00002210525,9.782347e-7,0.0005777752,0.00003569129,0.9920582,0.0007677595,0.0042014,0.001231706],"study_design_scores_gemma":[0.008711267,0.003509582,0.1896839,0.0001521299,0.0003538537,0.0002034499,0.002133112,0.03025047,0.2806697,0.006820481,0.4759978,0.001514248],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983664,0.0001203977,0.00001631165,0.000316537,0.00005563445,0.0002237009,0.000104501,0.000009922443,0.0007865857],"genre_scores_gemma":[0.9984615,0.0001167603,0.000393785,0.0006154457,0.00005074109,9.102194e-7,0.0003088537,0.00001577937,0.00003620808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7113886,"threshold_uncertainty_score":0.3640844,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2069576927","doi":"10.2337/diabetes.51.12.3586","title":"<i>PPARG</i> F388L, a Transactivation-Deficient Mutant, in Familial Partial Lipodystrophy","year":2002,"lang":"en","type":"article","venue":"Diabetes","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":263,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Western University; Robarts Clinical Trials","funders":"Canadian Diabetes Association; Heart and Stroke Foundation of Canada","keywords":"Peroxisome proliferator-activated receptor gamma; Lipodystrophy; Transactivation; Mutant; Medicine; Genetics; Biology; Gene; Peroxisome","retraction":null,"screen_n_in":null,"score":{"opus":0.006569257441088543,"gpt":0.1857855871865881,"spread":0.1792163297454995,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000412528,0.0001040621,0.00009595774,0.00003831427,0.00004467315,0.00001683239,0.00007329155,0.00009955023,0.00009998264],"category_scores_gemma":[0.00001850695,0.00009927677,0.00005907838,0.0001033964,0.00003799325,0.000004528501,0.00001204,0.00007497534,0.00002677818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008910421,"about_ca_system_score_gemma":0.00000649211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007295044,"about_ca_topic_score_gemma":0.000005870317,"domain_scores_codex":[0.9993116,0.0000256951,0.000132344,0.0002287698,0.00008728053,0.0002143241],"domain_scores_gemma":[0.9997416,0.000006015137,0.00003035615,0.0001628596,0.00001958625,0.00003960012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002363968,0.00007493411,0.006419598,0.000007869163,0.00001617679,0.000001455512,0.00008648935,0.0001312896,0.9842319,0.0000532404,0.0009635164,0.007989851],"study_design_scores_gemma":[0.001530982,0.0006746312,0.01368152,0.00001910717,0.0000264837,0.000002954501,0.00008765423,0.002501353,0.8899678,0.0001196853,0.09096504,0.0004227997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976426,0.0003001674,0.0001546835,0.0001072779,0.0002564994,0.00009324545,0.00001393939,0.00001372034,0.001417845],"genre_scores_gemma":[0.9991212,0.00003554319,0.00008940599,0.000321658,0.0002583338,0.00001416448,0.00003267937,0.0000151498,0.0001117927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09426415,"threshold_uncertainty_score":0.4048389,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2948716817","doi":"10.1161/circulationaha.118.039410","title":"Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies","year":2019,"lang":"en","type":"article","venue":"Circulation","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":260,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"Agence Nationale de la Recherche; National Institute for Health and Care Research","keywords":"Medicine; Internal medicine; Cardiology; Risk assessment; Ventricular tachycardia","retraction":null,"screen_n_in":null,"score":{"opus":0.01213807249480837,"gpt":0.2117109941193661,"spread":0.1995729216245578,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001149719,0.0000572596,0.00007126423,0.00005283419,0.00002722646,0.000007762066,0.00001699029,0.00008518227,0.000003432296],"category_scores_gemma":[0.00005155813,0.00005838451,0.0000213224,0.00005727884,0.000006830024,0.000008289676,0.00001130346,0.00002804391,0.000001141758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001308275,"about_ca_system_score_gemma":0.00003798888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001049352,"about_ca_topic_score_gemma":0.000004370891,"domain_scores_codex":[0.9995566,0.00001474096,0.0001513366,0.0001533209,0.00005881112,0.00006520868],"domain_scores_gemma":[0.9997634,0.000004832746,0.00009530567,0.00007840538,0.00003567874,0.00002232608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001113528,0.000009696259,0.8153787,0.00005998136,0.00002543252,3.194837e-7,0.000359745,0.003649294,0.1579263,0.0001074244,0.0000292446,0.02234248],"study_design_scores_gemma":[0.0009382563,0.00007932006,0.890705,0.00003240175,0.00002265212,0.000007554511,0.00008932392,0.001894998,0.1037053,0.0002086131,0.002225668,0.0000909446],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903373,0.000248881,0.008989907,0.000008020439,0.0001110812,0.0002646778,0.000003778607,0.000005521474,0.00003088748],"genre_scores_gemma":[0.9979216,0.00001903637,0.001712702,0.000008205557,0.0001000461,0.000007308244,0.0002003494,0.000008108971,0.00002257906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07532626,"threshold_uncertainty_score":0.2380851,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2161870945","doi":"10.1529/biophysj.106.086454","title":"Mechanical Properties of the Cell Nucleus and the Effect of Emerin Deficiency","year":2006,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":257,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Danmarks Grundforskningsfond","keywords":"Emerin; Lamin; Nuclear membrane; Nuclear lamina; Nucleus; Cell nucleus; Cell biology; Inner membrane; Chemistry; Nucleolus; Cytoplasm; Biophysics; Nuclear protein; Biology; Membrane; Biochemistry; Gene; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.002860783728575531,"gpt":0.174906273596929,"spread":0.1720454898683534,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009871312,0.00005605151,0.00009174201,0.000005836521,0.00006188852,0.000008490056,0.0001020273,0.00003890778,0.000002630816],"category_scores_gemma":[0.00001765036,0.00002300427,0.0001008265,0.00004192968,0.0001869602,0.000001540402,0.00005590646,0.0000802308,5.11433e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001937369,"about_ca_system_score_gemma":0.000008110618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001184165,"about_ca_topic_score_gemma":5.99072e-7,"domain_scores_codex":[0.999576,0.00008161088,0.0001152365,0.00006427553,0.00009471033,0.0000681893],"domain_scores_gemma":[0.9997676,0.000007173594,0.00008396538,0.0001027941,0.00002460546,0.00001385171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003008684,0.00001514819,0.0002089383,0.00001157231,0.000006439801,1.470845e-7,0.000008079681,0.000007154713,0.9984125,0.0002558659,0.0001371665,0.0006361546],"study_design_scores_gemma":[0.0006142155,0.0003334676,0.00340777,0.000007252677,0.00002861568,0.00001698096,0.000008882636,0.0000246978,0.9950234,0.00006634581,0.0004362224,0.0000321901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992776,0.0001514594,0.00005709906,0.00009193634,0.00009987817,0.00006168868,0.00000113689,0.000001007209,0.0002582245],"genre_scores_gemma":[0.9997159,0.00001479324,0.00002568055,0.00001761756,0.0001757091,7.624034e-7,2.989178e-7,0.000004865215,0.00004433801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003389106,"threshold_uncertainty_score":0.0938087,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2290633618","doi":"10.1200/jco.2015.65.3949","title":"First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":247,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute; Barbara Ann Karmanos Cancer Institute","keywords":"Medicine; Tolerability; Pharmacokinetics; Nausea; Response Evaluation Criteria in Solid Tumors; Vomiting; Adverse effect; Pharmacodynamics; Dosing; Anorexia; Internal medicine; Gastroenterology; Pharmacology; Hyponatremia; Toxicity; Phases of clinical research","retraction":null,"screen_n_in":null,"score":{"opus":0.01798342769741563,"gpt":0.3535464819057588,"spread":0.3355630542083432,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007314755,0.0001317236,0.0008721871,0.0001456907,0.0000180814,0.000001835411,0.0001560861,0.0002471917,0.00002407374],"category_scores_gemma":[0.0006732338,0.0000851181,0.0001207744,0.0001452991,0.0001155775,0.00001701375,0.00005594834,0.000313675,6.344913e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006412677,"about_ca_system_score_gemma":0.0001965088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002032549,"about_ca_topic_score_gemma":0.001000692,"domain_scores_codex":[0.9973603,0.0002028733,0.001825845,0.0002331797,0.0001955843,0.0001821401],"domain_scores_gemma":[0.9978228,0.0001520006,0.001478727,0.0001704639,0.0002899024,0.00008609057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02719363,0.01396244,0.921142,0.00003377453,0.0001999074,0.0001149613,0.0004645423,0.0002520027,0.01688276,0.00001688409,0.0006415609,0.0190955],"study_design_scores_gemma":[0.04458912,0.09267167,0.8552189,0.0001868593,0.00004928527,0.000009824928,0.0003631288,0.00001639011,0.0019367,0.00007810861,0.004717997,0.0001619798],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991813,0.00002421851,0.000009944893,0.0001542602,0.0002307955,0.0002552956,0.000004207578,0.0000013893,0.0001385514],"genre_scores_gemma":[0.9993872,0.00005198626,0.0002610343,0.00008261229,0.000181033,0.000002777123,0.000001857486,0.00001851004,0.00001298088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07870923,"threshold_uncertainty_score":0.3471015,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2055522522","doi":"10.1083/jcb.200704108","title":"Functional association of Sun1 with nuclear pore complexes","year":2007,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":241,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Nuclear pore; Inner membrane; Cell biology; Lamin; Membrane; Nucleus; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.005116574371048524,"gpt":0.2017835364110637,"spread":0.1966669620400152,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005186413,0.00005715411,0.0001030932,0.00003173757,0.00004164518,0.000002393725,0.00009078237,0.0000995413,0.0000625254],"category_scores_gemma":[0.00002659665,0.00003275439,0.0000504597,0.00004472478,0.00006151342,0.000002408256,0.00001962428,0.000104604,0.000002494162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001459596,"about_ca_system_score_gemma":0.00002667206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004977524,"about_ca_topic_score_gemma":0.00001437958,"domain_scores_codex":[0.9995232,0.00005781703,0.0001896674,0.00004896862,0.00007954059,0.0001008517],"domain_scores_gemma":[0.9992891,0.00003507323,0.0003779939,0.00008337179,0.0001900952,0.00002438806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008550218,0.00002019288,0.003303047,0.000003390451,0.00006256445,7.534717e-7,0.00003959459,0.0000322376,0.9926659,0.0001540511,0.00222379,0.0006394553],"study_design_scores_gemma":[0.001396438,0.00311412,0.07562313,0.000008442477,0.0001268441,0.0002239492,0.0004266519,0.000006630842,0.771296,0.0004958115,0.1471493,0.0001326455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956421,0.0001443729,0.001312159,0.000139459,0.0002047898,0.0000288702,0.000002955865,0.000001547934,0.002523695],"genre_scores_gemma":[0.9987868,0.00006708792,0.000358964,0.0001830636,0.0003245574,4.706143e-8,0.00001314205,0.000007259003,0.0002590765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2213699,"threshold_uncertainty_score":0.1335685,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2022903909","doi":"10.1016/j.molmed.2005.02.004","title":"Prohibitin: a potential target for new therapeutics","year":2005,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":234,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Prohibitin; Apoptosis; Inflammation; Cell biology; Mitochondrion; Biology; Function (biology); Cell cycle; Regulator; Cell; Suppressor; Cancer research; Programmed cell death; Cancer; Immunology; Biochemistry; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03176987045089749,"gpt":0.3473444621612597,"spread":0.3155745917103622,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001638561,0.0004243354,0.0008476755,0.0002603842,0.00003347397,0.00001061299,0.0002522208,0.0005288363,0.0001625341],"category_scores_gemma":[0.00003154692,0.0003277636,0.0003676339,0.0002659098,0.00007460645,0.00000191928,0.00005878888,0.0002588974,0.000007610212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000332482,"about_ca_system_score_gemma":0.0001288103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000801611,"about_ca_topic_score_gemma":0.00001041424,"domain_scores_codex":[0.9983493,0.00007819618,0.0004901693,0.0005577206,0.0001853447,0.0003392659],"domain_scores_gemma":[0.999179,0.000008369022,0.0002018481,0.0004692658,0.0000394244,0.0001021131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003691052,0.0000218112,2.610354e-7,0.0004379607,0.0001471523,0.00001542697,0.00001401436,0.000005953605,0.001484397,0.00006873869,0.008200247,0.9895671],"study_design_scores_gemma":[0.0009817663,0.0006045533,0.000002348004,0.0007516028,0.0005408413,0.00007336135,0.000005429084,0.00001080357,0.0001152377,0.00008926944,0.9965143,0.0003105487],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000006602778,0.9899441,0.007342502,0.0003277115,0.0004534587,0.0004133439,0.00002159121,0.00001715594,0.001473525],"genre_scores_gemma":[0.00004043612,0.9857067,0.004494485,0.0005501731,0.002898646,0.00005979764,0.002077889,0.00012169,0.004050122],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9892566,"threshold_uncertainty_score":0.9999174,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2104319976","doi":"10.1242/jcs.114.24.4447","title":"Nuclear envelope defects associated with<i>LMNA</i>mutations cause dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy","year":2001,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":230,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Lamin; LMNA; Emerin; Muscular dystrophy; Biology; Nuclear lamina; Progeria; Dilated cardiomyopathy; Inner membrane; Genetics; Point mutation; Mutation; Cell biology; Nuclear protein; Internal medicine; Gene; Medicine; Heart failure; Mitochondrion; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.00476347731021388,"gpt":0.1988437738205406,"spread":0.1940802965103267,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002976949,0.0001015112,0.0001346456,0.00009272413,0.0002126544,0.00006770049,0.0001589559,0.00006728117,0.00001058271],"category_scores_gemma":[0.00009470471,0.0000770397,0.00005918435,0.0003576406,0.0002351454,0.00002822695,0.00004665225,0.0001257463,0.000002509501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002582902,"about_ca_system_score_gemma":0.0001129656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004337141,"about_ca_topic_score_gemma":0.000006059395,"domain_scores_codex":[0.9991209,0.00003714565,0.0001772497,0.0001815651,0.0002878096,0.0001953396],"domain_scores_gemma":[0.9992462,0.000007935116,0.0002024586,0.0001341546,0.0002750939,0.0001341286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007480686,0.00002926234,0.006133287,0.000003529171,0.00003943799,0.00006844763,0.0001169912,0.0002338383,0.9923678,0.00001259146,0.0002383433,0.0006816802],"study_design_scores_gemma":[0.005642995,0.005956216,0.5285491,0.0001556847,0.0007121593,0.003169206,0.0009811551,0.0005931158,0.3771091,0.0003470329,0.07555705,0.001227158],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981019,0.000191978,0.0002866316,0.00005751223,0.0001640904,0.00005627994,0.000001953068,0.000005199279,0.00113444],"genre_scores_gemma":[0.9989288,0.0001661934,0.0005693989,0.0001148517,0.00009581316,3.925248e-7,0.0000030304,0.00001255482,0.0001089451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6152586,"threshold_uncertainty_score":0.3141588,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2096814753","doi":"10.1016/j.molcel.2006.02.015","title":"The Conserved Transmembrane Nucleoporin NDC1 Is Required for Nuclear Pore Complex Assembly in Vertebrate Cells","year":2006,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":229,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; University of Alberta","funders":"","keywords":"Nucleoporin; Nuclear pore; Biology; Cell biology; Biogenesis; Transmembrane protein; RNA interference; Cytosol; Cytoplasm; Nuclear transport; RNA; Biochemistry; Cell nucleus; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.007620049495842346,"gpt":0.206379370336587,"spread":0.1987593208407447,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001414108,0.0002002403,0.0001651409,0.00003337992,0.000169555,0.00006593282,0.0002392344,0.0001889119,0.00003772054],"category_scores_gemma":[0.000006821945,0.0001730348,0.0001764955,0.00009994675,0.00008278247,0.000004880062,0.00004091144,0.00009635636,0.00002118088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001644409,"about_ca_system_score_gemma":0.00003039741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006460072,"about_ca_topic_score_gemma":0.00007369245,"domain_scores_codex":[0.9987961,0.00006157147,0.0002722668,0.0003857391,0.0001336521,0.0003506815],"domain_scores_gemma":[0.9993806,0.00001167217,0.00008475335,0.0004089949,0.00006081512,0.00005315531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002147668,0.00004840751,0.00004239335,0.00002718038,0.00001927196,0.00001617327,0.00002821428,0.00007370195,0.9848614,0.000454258,0.01312111,0.001093139],"study_design_scores_gemma":[0.001334961,0.0002154219,0.0003250554,0.000005290718,0.00002431385,0.000006195673,0.00005872949,0.001292928,0.6683561,0.0004133145,0.3277403,0.0002273644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880703,0.0004230811,0.001239667,0.0008803303,0.0002630103,0.0005239636,0.00004150718,0.00002964121,0.008528517],"genre_scores_gemma":[0.9966784,0.00004807852,0.0007460854,0.001166901,0.0000942406,0.00001251308,0.0002197095,0.00006793861,0.0009661298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3165053,"threshold_uncertainty_score":0.7056153,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109167239","doi":"10.2337/db14-0318","title":"Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes","year":2014,"lang":"en","type":"article","venue":"Diabetes","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":228,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Medical Research Council; Novo Nordisk Fonden; Wellcome Trust","keywords":"Internal medicine; Insulin resistance; Endocrinology; Type 2 diabetes; Adiponectin; Medicine; Diabetes mellitus; Coronary artery disease; Adipose tissue; Lipodystrophy; Allele; Metabolic syndrome; Biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.009733793714062012,"gpt":0.2099625543949475,"spread":0.2002287606808855,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279778,0.0001737825,0.0001874959,0.00003903401,0.0001346641,0.00004116298,0.0001248893,0.000117437,0.00001241608],"category_scores_gemma":[0.0003405527,0.0001535275,0.0000639198,0.00008350563,0.00008706992,0.00001210488,0.0000812513,0.00006830732,0.000008688476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005105238,"about_ca_system_score_gemma":0.00003284648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.589935e-7,"about_ca_topic_score_gemma":0.000005466244,"domain_scores_codex":[0.9989648,0.00005304229,0.000183825,0.0004022918,0.0001013188,0.0002947002],"domain_scores_gemma":[0.9992374,0.00008449346,0.00006762492,0.0003225,0.0001566001,0.0001314057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004504635,0.00005155682,0.1873501,0.0002651956,0.000147233,0.000001728479,0.0000271194,0.00002251886,0.7747473,0.0002752541,0.006182158,0.03047932],"study_design_scores_gemma":[0.0007633139,0.0004898422,0.8440075,0.0001735192,0.0002052664,0.000001247319,0.000005092284,0.001176959,0.01619372,0.002611854,0.1339191,0.0004525346],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830563,0.01588209,0.0001685112,0.0001931523,0.0003494131,0.0002056803,0.00001381693,0.00002360731,0.0001074224],"genre_scores_gemma":[0.9943624,0.000604186,0.002317653,0.001516136,0.0007561476,0.00003004897,0.00009720009,0.00003555767,0.0002807083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7585536,"threshold_uncertainty_score":0.6260669,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2021302591","doi":"10.1007/s10038-003-0025-3","title":"LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090)","year":2003,"lang":"en","type":"article","venue":"Journal of Human Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":222,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials","funders":"Heart and Stroke Foundation of Canada","keywords":"LMNA; Progeria; Proband; Genetics; Biology; Lamin; Mutation; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01265211197634203,"gpt":0.2543844584861277,"spread":0.2417323465097857,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004250234,0.0002722609,0.0003909782,0.0002355407,0.00007738933,0.00005382222,0.0002614207,0.0003020413,0.00007824616],"category_scores_gemma":[0.00005622693,0.0002543353,0.0001651294,0.0002115154,0.00008694053,0.00001388187,0.00005065737,0.000403988,0.000008907479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005644441,"about_ca_system_score_gemma":0.0001499396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000093926,"about_ca_topic_score_gemma":0.00008395604,"domain_scores_codex":[0.9980283,0.0001244766,0.0008247788,0.0003252922,0.0002929873,0.0004041428],"domain_scores_gemma":[0.9989808,0.000007955016,0.0004004232,0.0003151198,0.0001628503,0.0001328151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003033082,0.0003736128,0.02902281,0.00008205825,0.0001608278,0.0004697998,0.0005622319,0.0003611261,0.9635681,0.0001657208,0.001837507,0.003092938],"study_design_scores_gemma":[0.006930601,0.004676366,0.1449014,0.0002630799,0.0001439744,0.004811267,0.0009619194,0.0001496101,0.7917475,0.002602861,0.0416061,0.001205312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978395,0.0008620702,0.00006698957,0.0001185252,0.0003629128,0.000262647,0.000008985213,0.000006455827,0.0004719888],"genre_scores_gemma":[0.9968281,0.0002887645,0.00196633,0.0003345399,0.0001657396,0.000005191662,0.00001679578,0.00005088093,0.0003435929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1718205,"threshold_uncertainty_score":0.9999909,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071417493","doi":"10.1093/emboj/19.16.4362","title":"Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes","year":2000,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":218,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SNC-Lavalin (Canada)","funders":"","keywords":"Biology; Mediator; Nuclear export signal; Nuclear transport; Cell nucleus; Cell biology; Nuclear protein; Genetics; Computational biology; Nucleus; Gene; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.01404718096567782,"gpt":0.2193995634569433,"spread":0.2053523824912655,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002205183,0.00008114751,0.0001028391,0.00002624511,0.00005672469,0.00001294843,0.0001502056,0.00006583005,0.001771965],"category_scores_gemma":[0.0000168513,0.00005373321,0.00007357754,0.00006134305,0.00005116197,0.000004526986,0.00002334522,0.0001576341,0.00001211959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007001314,"about_ca_system_score_gemma":0.00003470629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005082828,"about_ca_topic_score_gemma":0.00000375653,"domain_scores_codex":[0.9993703,0.00003053166,0.0002374631,0.0001000599,0.0001214485,0.0001401357],"domain_scores_gemma":[0.9996481,0.00000519416,0.0001053513,0.0001667939,0.00002803687,0.00004653042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004573842,0.0001452681,0.002722472,0.000007709163,0.00006594526,0.00002278966,0.000621937,0.00006504149,0.9675606,0.0002464977,0.006714629,0.02136967],"study_design_scores_gemma":[0.005361855,0.001473016,0.1743435,0.0001005796,0.00006436248,0.001721991,0.001203258,0.0001587871,0.18923,0.001432508,0.6242131,0.0006970546],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936628,0.00020156,0.00001337089,0.0003043499,0.0002129218,0.0000460647,0.000003354172,0.000003618127,0.005551902],"genre_scores_gemma":[0.9979378,0.000100297,0.0002614686,0.0003096639,0.0005602025,0.000001108923,0.00000382503,0.00001702848,0.0008086005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7783306,"threshold_uncertainty_score":0.9991406,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124295853","doi":"10.1093/hmg/ddi040","title":"MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-β signaling","year":2004,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":216,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Center for Research Resources; University of Ottawa; National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center; Muscular Dystrophy Association","keywords":"Transforming growth factor; Cell biology; Inner membrane; Signal transduction; Integral membrane protein; Chemistry; Membrane; Membrane protein; Biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.007334815266622223,"gpt":0.2121496554506478,"spread":0.2048148401840256,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006363824,0.0001862593,0.0001448018,0.00004571487,0.0001617245,0.00004068424,0.0001548253,0.000169124,0.000009985174],"category_scores_gemma":[0.00001100211,0.0001480001,0.00006828792,0.00007277221,0.0001948851,0.000007130855,0.00008150469,0.0001348787,3.693517e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008224018,"about_ca_system_score_gemma":0.00002518361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003440852,"about_ca_topic_score_gemma":0.00003307129,"domain_scores_codex":[0.9991262,0.00004791211,0.0001985817,0.000303028,0.0001376113,0.0001866693],"domain_scores_gemma":[0.999522,0.000001649702,0.00007442511,0.0002654902,0.00006265918,0.00007376325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002615515,0.00002505768,0.0004245777,0.00004289892,0.00003652267,0.000002820558,0.0002964556,0.0000401977,0.9967984,0.001348055,0.000002193824,0.0009566442],"study_design_scores_gemma":[0.0007332318,0.0005555836,0.005783093,0.00003408673,0.0000431399,0.00002755355,0.0001875011,0.00002006995,0.9905847,0.001262961,0.0005533393,0.0002147458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984566,0.0004146801,0.000593548,0.00005718751,0.00004636071,0.0002553043,0.0000113089,0.00001104254,0.0001539507],"genre_scores_gemma":[0.9981287,0.00006075912,0.001510298,0.0001469618,0.00006388299,0.000003652997,0.00001955571,0.0000442121,0.00002204082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006213727,"threshold_uncertainty_score":0.6035268,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2134058508","doi":"10.1086/505885","title":"Sequencing of the Reannotated LMNB2 Gene Reveals Novel Mutations in Patients with Acquired Partial Lipodystrophy","year":2006,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":199,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Saint John Regional Hospital; Robarts Clinical Trials; Western University","funders":"","keywords":"Genetics; Lipodystrophy; Gene; Computational biology; Biology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.006009681986647104,"gpt":0.2120933158018782,"spread":0.2060836338152311,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001111687,0.00009112235,0.0001541021,0.00003908856,0.00007749217,0.00001044187,0.0002073971,0.00002400605,0.000003001224],"category_scores_gemma":[0.00001288472,0.00005245043,0.0000647737,0.0001694178,0.0002763498,0.000003177707,0.00003526315,0.00007668034,2.270585e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002397636,"about_ca_system_score_gemma":0.00005618765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004127044,"about_ca_topic_score_gemma":0.00002794766,"domain_scores_codex":[0.9992082,0.00007518175,0.0003263731,0.00008925619,0.0001776636,0.0001233647],"domain_scores_gemma":[0.9989522,0.000007679505,0.000602588,0.0002318926,0.0001828503,0.00002278389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002243283,0.00005301497,0.03867134,0.000002652592,0.00005007317,9.842699e-7,0.0001537698,0.005476607,0.9546326,0.00001949011,0.0001054223,0.0006097248],"study_design_scores_gemma":[0.001191307,0.001968854,0.8620294,0.00002875606,0.00009627406,0.00003102142,0.0002039037,0.00003721595,0.1338971,0.0002178804,0.0001686582,0.0001296538],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993444,0.00006223574,0.000336974,0.00005259029,0.00006297598,0.00008730832,0.00001027367,0.0000013044,0.00004192172],"genre_scores_gemma":[0.9985354,0.000005627841,0.001139995,0.00007792039,0.0001828505,7.815289e-7,0.00001134057,0.00001561431,0.00003048146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.823358,"threshold_uncertainty_score":0.2138866,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2080458584","doi":"10.1083/jcb.200304080","title":"Nup358 integrates nuclear envelope breakdown with kinetochore assembly","year":2003,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":198,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Kinetochore; Biology; Mitosis; Cell biology; Chromosome segregation; Microtubule; Spindle checkpoint; Nucleoporin; Genetics; Cell nucleus; Nuclear transport; Cytoplasm; Chromosome","retraction":null,"screen_n_in":null,"score":{"opus":0.004023483047992631,"gpt":0.1971692063391086,"spread":0.1931457232911159,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002581958,0.0001181488,0.0001443941,0.00003413146,0.00006845641,0.0000111167,0.0001978078,0.0001287956,0.00009813104],"category_scores_gemma":[0.00005084118,0.00006031927,0.00005411564,0.00008051323,0.0001095714,0.000003773071,0.00002306788,0.0001935331,0.00001440374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000963754,"about_ca_system_score_gemma":0.00006932378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006316227,"about_ca_topic_score_gemma":0.000008420305,"domain_scores_codex":[0.9993357,0.0001639921,0.0001871466,0.00009673649,0.00005880367,0.0001575974],"domain_scores_gemma":[0.9993749,0.00001982039,0.000201288,0.0001795854,0.000173848,0.0000505428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000369505,0.00001983227,0.0003268689,0.000003149548,0.0000566077,0.00000292993,0.00006393141,0.00002405137,0.9953124,0.0004066541,0.002137194,0.001276854],"study_design_scores_gemma":[0.0007713864,0.002505445,0.001370676,0.000009680052,0.0000758792,0.0007764167,0.0003567862,0.000005510229,0.5334897,0.0003989896,0.460079,0.0001605156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864513,0.0005058113,0.0007364165,0.0001562978,0.0002465254,0.00005718473,0.000001928844,0.00000351699,0.01184102],"genre_scores_gemma":[0.9975641,0.0003418738,0.001096578,0.0004449878,0.0002005818,3.568612e-7,0.000005623423,0.00001764926,0.0003282411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4618227,"threshold_uncertainty_score":0.2459749,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2107404798","doi":"10.1186/gb-2010-11-12-r120","title":"Caenorhabditis elegans chromosome arms are anchored to the nuclear membrane via discontinuous association with LEM-2","year":2010,"lang":"en","type":"article","venue":"Genome biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Center for Research Resources; National Human Genome Research Institute; Washington University in St. Louis; National Institutes of Health; University of Washington; York University; University of Minnesota","keywords":"Caenorhabditis elegans; Biology; Human genetics; Genetics; Chromosome; Caenorhabditis; Association (psychology); Computational biology; Evolutionary biology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.00233277943200904,"gpt":0.1825512044407417,"spread":0.1802184250087327,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000145346,0.0001679976,0.0001761194,0.00003555353,0.0001567467,0.0000316895,0.0002409807,0.0002838585,0.0001512863],"category_scores_gemma":[0.00005087534,0.0001112517,0.000062005,0.000108261,0.00005776484,0.000004624935,0.00007879526,0.0002280469,0.0001076364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003242883,"about_ca_system_score_gemma":0.00002355422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008857527,"about_ca_topic_score_gemma":0.001323457,"domain_scores_codex":[0.9989963,0.00005596573,0.000149614,0.0003828083,0.0000802696,0.0003351111],"domain_scores_gemma":[0.9992735,0.00001002242,0.0001374799,0.0004097174,0.00008466039,0.00008462589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009524717,0.0000175137,0.005595783,0.000003434631,0.00008066313,0.000002535931,0.0001178309,0.000009290806,0.990976,0.00006703207,0.001326319,0.001708308],"study_design_scores_gemma":[0.0005465543,0.0009118406,0.08284072,0.000002942495,0.0000453746,0.00007806407,0.0001275429,0.000007542631,0.02822002,0.00007495707,0.8868217,0.0003227698],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951305,0.00007190136,0.0003332881,0.002811278,0.0007376805,0.000255214,0.00009420544,0.00002780689,0.0005380996],"genre_scores_gemma":[0.9958178,0.00002816252,0.000428136,0.001209381,0.001471848,0.00001930869,0.0002418817,0.0000357395,0.0007477038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.962756,"threshold_uncertainty_score":0.4536712,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1891037876","doi":"10.1111/j.1399-0004.2004.00315.x","title":"Hutchinson–Gilford progeria syndrome","year":2004,"lang":"en","type":"review","venue":"Clinical Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"LMNA; Progeria; Lamin; Biology; Genetics; Premature aging; Nuclear lamina; Point mutation; Mutation; Exon; Gene; Nuclear protein; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.07006326715358303,"gpt":0.4065157341953015,"spread":0.3364524670417184,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002702948,0.0004371016,0.001103613,0.00004566062,0.00007125486,0.00004090283,0.000437497,0.001295486,0.00005985229],"category_scores_gemma":[0.0001405328,0.0003603314,0.0009219007,0.0001270666,0.0001655398,0.000001241075,0.0002565855,0.0004913906,0.0002721823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002416591,"about_ca_system_score_gemma":0.0004261016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.068497e-7,"about_ca_topic_score_gemma":0.000003001531,"domain_scores_codex":[0.9976108,0.0001557146,0.0009760822,0.0007709138,0.0001542423,0.0003322694],"domain_scores_gemma":[0.9984602,0.00002850563,0.000363265,0.0008944623,0.00005898669,0.0001945744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001289843,0.00008191001,0.00002619849,0.002442376,0.0002675479,0.00002588179,0.000002195806,0.000002485155,0.000006049838,0.00004872588,0.002043981,0.9950398],"study_design_scores_gemma":[0.0002550826,0.0006007066,0.00005224852,0.0009714243,0.0004664884,0.0002541831,0.00000157449,7.343621e-7,0.000005282718,0.0001393766,0.996838,0.0004148515],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005140626,0.9962621,0.0001469508,0.00001198565,0.001871463,0.0005652373,0.00004480461,0.00002951032,0.0005539101],"genre_scores_gemma":[0.00006174003,0.9938467,0.003027573,0.0001390202,0.0009666499,0.00002943367,0.0005172194,0.0001199733,0.001291748],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9947941,"threshold_uncertainty_score":0.9998848,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2118040139","doi":"10.1091/mbc.e02-06-0319","title":"CRM1/Ran-Mediated Nuclear Export of p27<sup>Kip1</sup>Involves a Nuclear Export Signal and Links p27 Export and Proteolysis","year":2003,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Wellcome Trust; U.S. Department of Defense","keywords":"Nuclear export signal; Biology; Ran; Nuclear transport; Cytoplasm; Cell nucleus; Cell biology; Cell cycle; Nuclear protein; Proteolysis; Nuclear localization sequence; Molecular biology; Biochemistry; Cell; Transcription factor; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.004478506929938114,"gpt":0.1922263268977217,"spread":0.1877478199677836,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002873963,0.0002932964,0.0004070242,0.00007925752,0.0001223352,0.00001260125,0.0002567286,0.0006364053,0.0001239089],"category_scores_gemma":[0.0001039954,0.0002326161,0.0002038422,0.0001344382,0.0005888841,0.000007100125,0.0002207259,0.0002719053,0.000004694608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008124461,"about_ca_system_score_gemma":0.00005489058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002305476,"about_ca_topic_score_gemma":0.000001604756,"domain_scores_codex":[0.9983585,0.0002006928,0.0004348377,0.000550768,0.0001463239,0.0003088466],"domain_scores_gemma":[0.9988906,0.00001717741,0.0003040103,0.0005655936,0.0001105514,0.0001121091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001369682,0.0000798302,0.007029062,0.00006430775,0.0001479869,0.000006939263,0.0002206207,0.000012618,0.9912094,0.00023513,0.000468165,0.0003889098],"study_design_scores_gemma":[0.001285623,0.001087712,0.004359369,0.00002961823,0.0001908602,0.00007622551,0.0005663124,0.00013639,0.9638435,0.0005157408,0.0274951,0.0004134963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963174,0.001338087,0.0001925331,0.0001087395,0.00009104571,0.0003821086,0.00002579972,0.00001603018,0.00152821],"genre_scores_gemma":[0.9975109,0.0002538205,0.001448277,0.0004241469,0.00005089215,0.000009642292,0.00005767373,0.00005386059,0.0001907975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02736591,"threshold_uncertainty_score":0.948581,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029040415","doi":"10.1016/j.mad.2009.03.001","title":"Telomere length in Hutchinson-Gilford Progeria Syndrome","year":2009,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency; University of British Columbia","funders":"","keywords":"LMNA; Progeria; Telomere; Lamin; Biology; Genetics; Premature aging; Molecular biology; Senescence; Mutant; Chromosome; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.005803642749922708,"gpt":0.2045711042893192,"spread":0.1987674615393965,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001143618,0.00009428474,0.0001140505,0.00005062116,0.00004348265,0.000009399924,0.00005295252,0.00007890214,0.000008543755],"category_scores_gemma":[0.000009750132,0.00008568704,0.00001707456,0.00004707995,0.000009803037,0.000003462376,0.00003170736,0.00004888046,0.000001942827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008086061,"about_ca_system_score_gemma":0.00003300792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006429855,"about_ca_topic_score_gemma":0.00001144376,"domain_scores_codex":[0.9994356,0.00001183847,0.0001584298,0.000185955,0.00007639314,0.0001318009],"domain_scores_gemma":[0.9998084,0.000001752576,0.00004409699,0.00009534857,0.00001624065,0.00003420142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001351884,0.00009716579,0.0008609159,0.00005427479,0.00004423669,0.00005920879,0.000463426,0.00001999791,0.817386,0.003064077,0.0001458317,0.1776697],"study_design_scores_gemma":[0.0012561,0.001101144,0.2363379,0.0001053006,0.00001074417,0.0001562162,0.0003797354,0.00002357978,0.7371865,0.007423087,0.01552474,0.0004949537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957958,0.0001156049,0.003384538,0.00005288686,0.0000802086,0.00009792917,8.866223e-7,0.000009464619,0.0004626731],"genre_scores_gemma":[0.9797706,0.00002560748,0.01992609,0.0001299192,0.00001345998,0.000003380341,0.00001572524,0.000007040011,0.0001082039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.235477,"threshold_uncertainty_score":0.3494216,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2070156993","doi":"10.1073/pnas.101329598","title":"Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis","year":2001,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Granzyme; Perforin; Cell biology; Cytotoxic T cell; Caspase; Biology; Granzyme A; Granzyme B; Cytolysin; Chemistry; Apoptosis; Programmed cell death; Biochemistry; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.01055203791890552,"gpt":0.2400222623210345,"spread":0.2294702244021289,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002647456,0.00006501348,0.00007380559,0.00004082346,0.0002399833,0.00002238745,0.0001913269,0.0000632957,0.000003721051],"category_scores_gemma":[0.0001407189,0.00003686628,0.00003320457,0.0002131914,0.0006106587,0.00001911881,0.0001109756,0.00006901082,2.830542e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003652521,"about_ca_system_score_gemma":0.00000413828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004003549,"about_ca_topic_score_gemma":3.7252e-7,"domain_scores_codex":[0.9993623,0.000005222649,0.0001151653,0.0001698972,0.0002584349,0.00008891375],"domain_scores_gemma":[0.9997649,0.0000190471,0.0001218256,0.000008196028,0.00006572876,0.00002031739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000450204,0.000009372395,0.01469646,0.00001801954,0.0000180875,9.513208e-9,0.0001458796,0.000001815336,0.9824373,0.001753537,0.000207108,0.0006673861],"study_design_scores_gemma":[0.0003586883,0.0001172071,0.7138407,0.00003169433,0.00003459507,0.00007941347,0.0005614918,0.0002737346,0.2761389,0.003815832,0.004623845,0.0001239564],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961663,0.0002352277,1.987369e-7,0.001314666,0.000009459751,0.0000694925,0.000006065398,0.000004019661,0.002194594],"genre_scores_gemma":[0.9992278,0.0003089554,0.00009249338,0.0001570255,0.00006721435,0.000001889197,2.611253e-7,0.000003846784,0.0001405156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7062985,"threshold_uncertainty_score":0.2249997,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4282925643","doi":"10.1126/science.abm9129","title":"Architecture of the cytoplasmic face of the nuclear pore","year":2022,"lang":"en","type":"article","venue":"Science","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":168,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Nucleoporin; Nuclear pore; Cytoplasm; Cell biology; Biophysics; Chemistry; Ribonucleoprotein; Transport protein; Nuclear transport; Biology; Cell nucleus; Biochemistry; RNA; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.002937702470981038,"gpt":0.186613681137429,"spread":0.183675978666448,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001077324,0.00003117061,0.00003141568,0.00001062783,0.0002023603,0.000003217675,0.0004680937,0.00001343435,0.0000292942],"category_scores_gemma":[0.00003170401,0.00001721868,0.00004308971,0.0002244765,0.0003376467,0.00000107601,0.0003851141,0.00007114281,3.080272e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005705223,"about_ca_system_score_gemma":0.00006279934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004454042,"about_ca_topic_score_gemma":0.000003157738,"domain_scores_codex":[0.9995661,0.00002301152,0.00005273545,0.0001082027,0.0001799752,0.00006995557],"domain_scores_gemma":[0.9996178,0.000001794314,0.00005667637,0.0002937222,0.00001980862,0.00001019676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009816441,0.000004792467,0.0008193102,0.000002142956,0.000001744353,4.211627e-8,0.0001475931,0.0006981181,0.9967539,0.0002509053,0.0003057293,0.001005848],"study_design_scores_gemma":[0.00015524,0.0001848802,0.06368375,0.000004707384,0.000008781739,0.00004629644,0.0006269775,0.0001041024,0.7935092,0.0006808673,0.1409166,0.00007850661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99784,0.00003603569,0.00001669699,0.0003186958,0.0002851554,0.0000561515,0.000009718739,0.000001445659,0.001436049],"genre_scores_gemma":[0.9994117,0.000001470927,0.00005788577,0.0002168838,0.00001639063,6.690985e-7,5.753025e-7,0.000002993975,0.0002914215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2032447,"threshold_uncertainty_score":0.1556412,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2143432207","doi":"10.1083/jcb.153.7.1465","title":"Nup2p Dynamically Associates with the Distal Regions of the Yeast Nuclear Pore Complex","year":2001,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":167,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Center for Research Resources","keywords":"Nucleoporin; Nuclear pore; Nucleoplasm; Ran; Nuclear transport; Cytoplasm; Cell biology; Compartment (ship); GTP'; Nucleus; Chemistry; Biology; Cell nucleus; Biophysics; Biochemistry; Nucleolus","retraction":null,"screen_n_in":null,"score":{"opus":0.005335352529553138,"gpt":0.197223957805358,"spread":0.1918886052758049,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001854755,0.00007699733,0.0001134147,0.00001108619,0.0001189161,0.000005885827,0.000344459,0.00008150493,0.00003361015],"category_scores_gemma":[0.00002240369,0.00002955464,0.00009670912,0.00006399463,0.0002984152,0.000001992573,0.00007048398,0.0001674795,0.000001547985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009027513,"about_ca_system_score_gemma":0.0000309873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001108909,"about_ca_topic_score_gemma":0.00004717105,"domain_scores_codex":[0.9994354,0.0001608115,0.000155702,0.00006026834,0.00007217258,0.0001155987],"domain_scores_gemma":[0.999325,0.0000246134,0.0003127593,0.0002105968,0.0001041473,0.00002287736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003707872,0.00002851626,0.001271974,0.000002196982,0.00008155871,0.000001287272,0.0001165926,0.00003688083,0.9939365,0.000378741,0.003337942,0.0004370448],"study_design_scores_gemma":[0.002868935,0.004983419,0.1475203,0.00004667888,0.0006186959,0.002065206,0.003392265,0.0002390596,0.07504693,0.003783166,0.7589667,0.000468597],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941955,0.000121314,0.0002158708,0.00232958,0.0001113284,0.0000570631,0.000009181549,0.000001708403,0.002958517],"genre_scores_gemma":[0.9989072,0.0001480721,0.00005773055,0.0004321649,0.0001732581,1.958032e-7,0.000007764987,0.00001011759,0.0002635054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9188895,"threshold_uncertainty_score":0.1205203,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2025059119","doi":"10.1016/j.jsb.2003.12.008","title":"A role for macromolecular crowding effects in the assembly and function of compartments in the nucleus","year":2004,"lang":"en","type":"article","venue":"Journal of Structural Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Hotel Dieu Hospital","funders":"","keywords":"Macromolecular crowding; Nucleus; Function (biology); Crowding; Macromolecular Substances; Macromolecule; Biophysics; Neuroscience; Cell biology; Biology; Chemistry; Nanotechnology; Biochemistry; Materials science","retraction":null,"screen_n_in":null,"score":{"opus":0.006086778256215227,"gpt":0.2506863992786654,"spread":0.2445996210224501,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002476156,0.00007675871,0.0001362995,0.00004832772,0.00003681611,0.00001076497,0.0001293288,0.00008801038,8.676366e-7],"category_scores_gemma":[0.00004933415,0.00004095554,0.00005988836,0.00006344687,0.00005325063,0.000005824841,0.00001776655,0.0001087647,9.80573e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001023273,"about_ca_system_score_gemma":0.00001649958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001511135,"about_ca_topic_score_gemma":0.0000284481,"domain_scores_codex":[0.9994385,0.00009528875,0.0002106415,0.00008848,0.00005453522,0.0001125192],"domain_scores_gemma":[0.9996762,0.00003389597,0.0001567275,0.00008268887,0.0000374515,0.00001306333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003974688,0.00001334455,0.007397979,0.00001736643,0.00003625792,0.000003905587,0.000257594,0.00008372832,0.9859829,0.001354913,0.0000319339,0.004422592],"study_design_scores_gemma":[0.005011404,0.004960759,0.8638824,0.00004671788,0.0000880879,0.0006394276,0.0009982723,0.00005164122,0.09210324,0.02840164,0.003641444,0.0001750038],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984514,0.0006349983,0.0003607425,0.0001828634,0.0001681427,0.0001622979,0.000003770034,5.833315e-7,0.00003518673],"genre_scores_gemma":[0.9990309,0.00002264623,0.0004847383,0.0003249129,0.0001196509,0.000002688232,0.00000925514,0.000004384019,7.575115e-7],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8938797,"threshold_uncertainty_score":0.1670118,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2091602799","doi":"10.1016/j.yjmcc.2007.11.008","title":"Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"National Heart, Lung, and Blood Institute","keywords":"LMNA; Haploinsufficiency; Lamin; Dilated cardiomyopathy; Cardiomyopathy; Internal medicine; Myocyte; Medicine; Biology; Cardiology; Endocrinology; Heart failure; Genetics; Phenotype; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.005031277581394706,"gpt":0.1996784256910227,"spread":0.194647148109628,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006390908,0.0001914983,0.0004150275,0.0001298803,0.000100472,0.00002527479,0.00008342193,0.0002137765,0.000001349699],"category_scores_gemma":[0.0000668428,0.0001660283,0.0002553198,0.0000958032,0.0001422456,0.000009976569,0.00006222876,0.0001737836,0.000001000303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002430898,"about_ca_system_score_gemma":0.0000582809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006546091,"about_ca_topic_score_gemma":5.444917e-7,"domain_scores_codex":[0.9987385,0.0001839998,0.0003736697,0.0002802313,0.0001716403,0.0002519653],"domain_scores_gemma":[0.9991487,0.00001399655,0.0002062989,0.0002187504,0.0001877943,0.0002244152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003381316,0.00001223674,0.004996113,0.00005118152,0.0003046368,0.0002030539,0.00003630829,0.00008778587,0.9918678,0.0002501792,0.0001659567,0.001686597],"study_design_scores_gemma":[0.002746057,0.002088007,0.03306365,0.00009169822,0.001538354,0.002478362,0.002109468,0.00004983537,0.9168128,0.0001470138,0.03800467,0.0008700473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736801,0.01249318,0.0124087,0.00003291502,0.0008945252,0.0001253102,0.00001036575,0.00001009561,0.0003448097],"genre_scores_gemma":[0.9987038,0.0004559428,0.0001571939,0.00005411062,0.000543902,0.000001572639,0.00002673178,0.00002499468,0.00003175496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07505498,"threshold_uncertainty_score":0.6770436,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2001971523","doi":"10.1038/ncomms2885","title":"Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model","year":2013,"lang":"en","type":"article","venue":"Nature Communications","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":161,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Aging","funders":"School of Medicine, New York University; Universität Greifswald; University of Hong Kong","keywords":"Progeria; LMNA; Lamin; Premature aging; Biology; Heterochromatin; Cell biology; EZH2; DNA repair; Cancer research; Epigenetics; Genetics; Chromatin; DNA; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.0090212509912906,"gpt":0.2564918950901989,"spread":0.2474706440989083,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001661259,0.00009718771,0.00007774515,0.00003153944,0.0001754121,0.0000355127,0.0003278209,0.0002223457,0.000004636961],"category_scores_gemma":[0.000119238,0.00007153617,0.00004901421,0.00008870399,0.0001016603,0.000009001517,0.0001761526,0.0004202371,0.000002130598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007714449,"about_ca_system_score_gemma":0.0000290785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007049698,"about_ca_topic_score_gemma":0.0006540873,"domain_scores_codex":[0.999403,0.00009754644,0.0001385248,0.0001772999,0.00005537731,0.0001282221],"domain_scores_gemma":[0.9988325,0.00003205115,0.00003485636,0.0009940999,0.00006831115,0.00003815865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001828189,0.00004088945,0.0021926,0.000007747723,0.00003087389,9.557588e-8,0.0002552193,0.00001723451,0.9895995,0.001926402,0.001571401,0.004339796],"study_design_scores_gemma":[0.00423706,0.0008656766,0.2499768,0.0000995228,0.0003141977,0.0001110222,0.00279567,0.1601084,0.3450495,0.005158915,0.2289828,0.002300326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992295,0.003208473,0.0001246573,0.003233257,0.00003607016,0.0003345033,0.000008991189,0.00003413125,0.0007248844],"genre_scores_gemma":[0.9910886,0.0005785045,0.007029541,0.0009249215,0.00004160772,0.0000894714,0.00006207084,0.00001747477,0.0001678188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6445499,"threshold_uncertainty_score":0.2917161,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2120902817","doi":"10.1136/jmg.2003.015651","title":"Novel lamin A/C gene (<i>LMNA</i>) mutations in atypical progeroid syndromes","year":2004,"lang":"en","type":"letter","venue":"Journal of Medical Genetics","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":158,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"LMNA; Lamin; Genetics; Progeria; Biology; Gene; Mutation","retraction":null,"screen_n_in":null,"score":{"opus":0.01394068568566487,"gpt":0.2606807972571064,"spread":0.2467401115714415,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003484419,0.0002506891,0.0003975887,0.0001619962,0.00003522685,0.00003182827,0.0004952605,0.001650565,0.00009705478],"category_scores_gemma":[0.0002741086,0.0002118914,0.0002288577,0.0001301227,0.000159942,0.000003157333,0.0001081968,0.001762681,0.00001014732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006026366,"about_ca_system_score_gemma":0.0007616026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004385653,"about_ca_topic_score_gemma":0.00001718152,"domain_scores_codex":[0.9975587,0.00007236878,0.0007286066,0.0002658764,0.001058392,0.0003160204],"domain_scores_gemma":[0.9990098,0.00002825034,0.0003691031,0.0002598486,0.0001637518,0.0001692522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002640086,0.0004120156,0.0009737156,0.0002813101,0.0005767395,0.003283267,0.0001412662,0.0004109778,0.09360731,0.00002479231,0.8846245,0.0154001],"study_design_scores_gemma":[0.002053658,0.0007651011,0.001953882,0.0002039717,0.0001394579,0.005221645,0.00002321513,0.00003952046,0.008983145,0.0003256977,0.979928,0.0003627098],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.4323694,0.009039813,0.01286296,0.5403433,0.004470172,0.0005447781,0.00009468534,0.00001686758,0.0002580526],"genre_scores_gemma":[0.1263097,0.00964916,0.05288671,0.7547725,0.05197117,0.00003081411,0.001650811,0.0004575898,0.002271477],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3060597,"threshold_uncertainty_score":0.9996455,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1966205440","doi":"10.1083/jcb.200205068","title":"The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint","year":2002,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleoporin; Nuclear pore; Kinetochore; Biology; Spindle checkpoint; Cell biology; G2-M DNA damage checkpoint; Cell cycle checkpoint; Saccharomyces cerevisiae; Spindle pole body; Nuclear transport; Spindle apparatus; Cell cycle; Cell nucleus; Genetics; Yeast; Cell division; Cell; Nucleus; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01409884709805902,"gpt":0.2061246253130554,"spread":0.1920257782149964,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002231801,0.00009284647,0.0001206276,0.00001637672,0.00015224,0.00000984085,0.000349664,0.00007129344,0.00007769251],"category_scores_gemma":[0.00002592461,0.00003754799,0.00009914102,0.00005233285,0.0002146912,0.000003581131,0.00008648109,0.0001892137,0.000007539496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001022156,"about_ca_system_score_gemma":0.0000165723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007482245,"about_ca_topic_score_gemma":0.00001237849,"domain_scores_codex":[0.9993054,0.0001506813,0.0002426951,0.00007235481,0.0001028799,0.0001259543],"domain_scores_gemma":[0.9991571,0.00002527126,0.0004031064,0.0002340214,0.0001501166,0.00003042121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004128869,0.00003783128,0.0002314827,0.000003479566,0.00008108846,6.823675e-7,0.00007345974,0.00004975678,0.9951355,0.00007158364,0.002781505,0.001120717],"study_design_scores_gemma":[0.002021511,0.00362996,0.08005373,0.00004582264,0.0001867222,0.001004936,0.0006313581,0.0003825272,0.3294966,0.0004154449,0.5818819,0.000249566],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948273,0.0002528201,0.00006675091,0.0008404362,0.0003694701,0.00006724847,0.000004409517,0.000001618171,0.003569951],"genre_scores_gemma":[0.998862,0.0001604967,0.0000790598,0.0003648332,0.0002256499,2.686916e-7,0.000005724312,0.00001141377,0.0002905739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.665639,"threshold_uncertainty_score":0.1531162,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1987452803","doi":"10.1016/j.celrep.2012.07.007","title":"The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation","year":2012,"lang":"en","type":"article","venue":"Cell Reports","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Cancer Institute; U.S. Public Health Service","keywords":"EIF4E; Nucleoporin; Nuclear pore; Nuclear export signal; Cell biology; Translation (biology); Biology; Eukaryotic translation; Oncogene; Messenger RNA; RNA; Cytoplasm; Cell nucleus; Nuclear transport; Genetics; Gene; Cell cycle","retraction":null,"screen_n_in":null,"score":{"opus":0.01103115351199518,"gpt":0.2310902168053845,"spread":0.2200590632933893,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003959406,0.0001122883,0.00008023591,0.00001092976,0.0002955614,0.00004803563,0.00007440188,0.00008628258,0.00001819966],"category_scores_gemma":[0.00002221496,0.00006684898,0.00006682047,0.00006092786,0.00005848607,0.000007796295,0.00005310968,0.00007686135,0.00000779912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001080771,"about_ca_system_score_gemma":0.00001861885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001066815,"about_ca_topic_score_gemma":0.000007030496,"domain_scores_codex":[0.9991674,0.00002692032,0.0002383905,0.000203129,0.0001317907,0.0002323646],"domain_scores_gemma":[0.9992732,0.000003932187,0.0001179114,0.0004544953,0.00004512405,0.000105359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008416703,0.0000459039,0.001433928,0.00001594692,0.00004460445,0.00001460266,0.001011536,0.000004143542,0.8525292,0.00006976535,0.008645076,0.1361011],"study_design_scores_gemma":[0.00008867152,0.00015498,0.005983855,0.000002811196,0.00002768767,0.0005507945,0.0002426494,0.00001030179,0.06274328,0.00005014336,0.9300366,0.000108252],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903859,0.0005895035,0.0001058913,0.0004058146,0.0003600999,0.0004011306,0.000001430935,0.00001924164,0.007730911],"genre_scores_gemma":[0.9982376,0.0001189881,0.0003055856,0.0003532722,0.0003376344,0.00001378595,0.00006403685,0.00002269428,0.0005464799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9213915,"threshold_uncertainty_score":0.2726023,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2015953599","doi":"10.1371/journal.ppat.1000741","title":"Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket","year":2010,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; Michael Smith Health Research BC","keywords":"Nuclear transport; Capsid; Nuclear pore; Nucleoporin; Genome; Importin; Biology; Virology; Cell nucleus; Cell biology; Cytoplasm; Genetics; Virus; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.005560697147061399,"gpt":0.2027088490925221,"spread":0.1971481519454607,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002459949,0.0001569981,0.0001525029,0.00003578697,0.0001256786,0.00002777715,0.0003850564,0.0001897712,0.0002416625],"category_scores_gemma":[0.00009451718,0.0001015231,0.0001172595,0.0001276211,0.0001488507,0.000006059312,0.00009908571,0.0003036318,0.00004080621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006231245,"about_ca_system_score_gemma":0.00002804017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002676466,"about_ca_topic_score_gemma":0.001118412,"domain_scores_codex":[0.9989612,0.00008644674,0.000240031,0.0002727459,0.0002076938,0.0002319061],"domain_scores_gemma":[0.9990909,0.00001720538,0.0001088857,0.0006847206,0.00005120377,0.00004711946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005131174,0.00008764493,0.018124,0.00001218719,0.00003327346,0.00001447382,0.0005209507,0.000002755743,0.9768808,0.0009022186,0.002364234,0.001006093],"study_design_scores_gemma":[0.0008702528,0.000816685,0.5601262,0.00002987439,0.0001428372,0.000156666,0.0008476856,0.0003892636,0.07918297,0.0006263817,0.3562173,0.0005938594],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959972,0.00004799583,0.000002388521,0.0002822586,0.0003405195,0.0002057645,0.00006328655,0.00001421694,0.00304638],"genre_scores_gemma":[0.9983032,0.0001624086,0.0002612483,0.0007531887,0.0003851735,0.000007539996,0.00003477101,0.00004358297,0.00004887059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8976979,"threshold_uncertainty_score":0.4139993,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109259135","doi":"10.1091/mbc.e05-09-0894","title":"UNC-83 Is a KASH Protein Required for Nuclear Migration and Is Recruited to the Outer Nuclear Membrane by a Physical Interaction with the SUN Protein UNC-84","year":2006,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences; National Institutes of Health; Universität Zürich; Pennsylvania State University","keywords":"Biology; Lamin; Nuclear lamina; Inner membrane; Cell biology; Nuclear protein; Caenorhabditis elegans; Nucleus; Genetics; Gene; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.004438343772690831,"gpt":0.2103443652039782,"spread":0.2059060214312874,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220545,0.0001839803,0.0001533205,0.00002286361,0.0001868868,0.00003188257,0.0002548844,0.0001630797,0.00001205644],"category_scores_gemma":[0.00001822116,0.00009563291,0.0001206686,0.0001072101,0.0001828806,0.000006390384,0.0001144764,0.0001268005,0.000005678016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001320073,"about_ca_system_score_gemma":0.00001452508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001618576,"about_ca_topic_score_gemma":0.00006297903,"domain_scores_codex":[0.999054,0.0001428813,0.000156638,0.00035981,0.00009283228,0.0001938822],"domain_scores_gemma":[0.9992704,0.000009001547,0.000153481,0.0004540823,0.00008357451,0.00002941328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005049041,0.00004522861,0.00001690876,0.0000198268,0.00005184383,2.964924e-7,0.0002712799,0.00001154576,0.9880542,0.0002592358,0.01020236,0.0005624277],"study_design_scores_gemma":[0.0004544925,0.0007302836,0.00005959202,0.00001551751,0.00005095074,0.000007349964,0.0001067286,0.0001874928,0.8290898,0.0003248201,0.1688448,0.0001281658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877405,0.00009132193,0.001081116,0.009414804,0.00005792069,0.001357735,0.0000471158,0.0000117982,0.0001976794],"genre_scores_gemma":[0.99621,0.000003081892,0.000599909,0.002003437,0.0001216423,0.00006425074,0.0000642583,0.00003929361,0.0008940654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1589643,"threshold_uncertainty_score":0.3899797,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124276277","doi":"10.1161/01.cir.103.18.2225","title":"Premature Atherosclerosis Associated With Monogenic Insulin Resistance","year":2001,"lang":"en","type":"article","venue":"Circulation","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"LMNA; Insulin resistance; Medicine; Hyperinsulinemia; Dyslipidemia; Internal medicine; Endocrinology; Lipodystrophy; Cardiology; Insulin; Disease; Immunology; Lamin","retraction":null,"screen_n_in":null,"score":{"opus":0.008529319357696012,"gpt":0.1979859609181235,"spread":0.1894566415604274,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005103429,0.0000787004,0.00006092813,0.00001726704,0.00007095588,0.00001685953,0.00004603584,0.0001317592,0.00002809298],"category_scores_gemma":[0.00003407704,0.00007005709,0.00003291681,0.0001151237,0.000019421,0.000004850991,0.000009410089,0.00005093886,0.000007268903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001989693,"about_ca_system_score_gemma":0.00001416785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001969908,"about_ca_topic_score_gemma":0.00007146798,"domain_scores_codex":[0.9995197,0.00002142172,0.00008145433,0.0001874257,0.00008656538,0.0001034405],"domain_scores_gemma":[0.9996687,0.000003294488,0.00006342123,0.0001770497,0.00006047411,0.00002704829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002688723,0.0000479219,0.2004857,0.00000857729,0.0001016271,0.000001508005,0.0001168118,0.000437132,0.7945638,0.0001173767,0.00178674,0.002063895],"study_design_scores_gemma":[0.00047436,0.00004583154,0.9845713,0.00002049626,0.00002304359,0.00000461145,0.00001442183,0.0001249479,0.005909864,0.0002005966,0.008478483,0.0001320798],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959806,0.0002274587,0.001472769,0.00005793524,0.00006566352,0.0001046319,0.000003672365,0.00002415226,0.002063074],"genre_scores_gemma":[0.9989554,0.00004196134,0.0001430471,0.0001148259,0.0001202235,0.000006029015,0.0001670239,0.00001779691,0.000433641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.788654,"threshold_uncertainty_score":0.2856845,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1964824076","doi":"10.1182/blood-2013-04-495374","title":"Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":146,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Cancer Institute; National Institute for Health and Care Research","keywords":"Karyopherin; Cytarabine; Internal medicine; Medicine; Cancer research; Pharmacology; Leukemia; Cell nucleus; Nuclear transport","retraction":null,"screen_n_in":null,"score":{"opus":0.01031255958674991,"gpt":0.261727777448571,"spread":0.2514152178618211,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002065219,0.00009776746,0.0001392136,0.00001332433,0.00002956084,0.00001508991,0.00007037066,0.0002218988,0.00003324743],"category_scores_gemma":[0.0001475906,0.00007116381,0.00007179688,0.00005300366,0.000138902,0.000005563773,0.00008345339,0.0001643434,0.000010811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003725743,"about_ca_system_score_gemma":0.00002746503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005595098,"about_ca_topic_score_gemma":0.00002460772,"domain_scores_codex":[0.9990982,0.00009863077,0.0003438345,0.0002520153,0.00007962873,0.0001277206],"domain_scores_gemma":[0.9995391,0.00005807382,0.00009072681,0.0002269919,0.00003481992,0.00005029279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002607099,0.0008058773,0.112407,0.00003319967,0.0001175957,0.000002735049,0.00008216025,0.000002447675,0.8339034,0.00004780528,0.02350427,0.0288328],"study_design_scores_gemma":[0.009655314,0.002106158,0.6675149,0.00005880976,0.0001287034,0.00004956625,0.000132758,0.00005651881,0.2996819,0.0003006519,0.01994593,0.0003688765],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984568,0.0004279494,0.00001765558,0.0001845435,0.0001434109,0.0002270322,0.000006060572,0.000006665096,0.0005298899],"genre_scores_gemma":[0.9989274,0.0001698338,0.0001624181,0.0002026812,0.0003536746,0.000008361018,0.00003622145,0.00001343846,0.0001259421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5551079,"threshold_uncertainty_score":0.2901976,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}