{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":1834,"total_is_capped":false,"direct_labels_cover":2,"predictions_cover":1834,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"23a4b58a8523","filters":{"topic":"Pluripotent Stem Cells Research"}},"results":[{"id":"W2058521801","doi":"10.1038/nature06968","title":"The ground state of embryonic stem cell self-renewal","year":2008,"lang":"en","type":"article","venue":"Nature","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3535,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; McMaster University","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research","keywords":"Embryonic stem cell; Cell biology; Induced pluripotent stem cell; Biology; Stem cell; Kinase; Cellular differentiation; Genetics","authors":[{"name":"Qi‐Long Ying","is_ca":false},{"name":"Jason Wray","is_ca":false},{"name":"Jennifer Nichols","is_ca":false},{"name":"Laura Batlle‐Morera","is_ca":false},{"name":"Bradley W. Doble","is_ca":true},{"name":"James R. Woodgett","is_ca":true},{"name":"Philip Cohen","is_ca":false},{"name":"Austin Smith","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006992035737366256,"gpt":0.2410478230602973,"spread":0.2340557873229311,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005297101,0.0001414555,0.0002779817,0.0003297677,0.0004674827,0.002852087,0.0005053352,0.0008646293,0.003128008],"category_scores_gemma":[0.001125251,0.0002152848,0.0001527408,0.0003260333,0.001581275,0.003160178,0.0008068994,0.00154022,0.0009485721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007836713,"about_ca_system_score_gemma":0.000597392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003022723,"about_ca_topic_score_gemma":0.0002720029,"domain_scores_codex":[0.9997894,0.00002048835,0.00001505459,0.00004553587,0.00008598017,0.00004362594],"domain_scores_gemma":[0.9995789,0.0001582044,0.00004612887,0.00009639054,0.00006155167,0.00005875188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002766565,0.00006720638,0.001910527,0.0002493586,0.00003139134,0.0002244247,0.0005176013,0.001265791,0.3314369,0.5747952,0.005303159,0.08392179],"study_design_scores_gemma":[0.0000667297,0.000448192,0.01021771,0.0001383419,0.00004956964,0.0006714813,0.0006817818,0.005884424,0.28921,0.5816585,0.1109163,0.00005703085],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.78067,0.03485392,0.08242687,0.01909888,0.001659661,0.00005584215,0.001444547,0.0008516085,0.07893866],"genre_scores_gemma":[0.9848722,0.004754162,0.003134819,0.000503325,0.0002815916,0.00002523202,0.0004561663,0.00005416742,0.005918341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003128008,"threshold_uncertainty_score":0.01046425,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2158979552","doi":"10.1038/nature07863","title":"piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells","year":2009,"lang":"en","type":"article","venue":"Nature","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1797,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Wellcome Trust","keywords":"Reprogramming; Induced pluripotent stem cell; Biology; SOX2; Transposase; KLF4; Embryonic stem cell; Cell biology; Transgene; Somatic cell; Stem cell; Genetics; Molecular biology; Transposable element; Cell; Gene; Genome","authors":[{"name":"Knut Woltjen","is_ca":true},{"name":"Iacovos P. Michael","is_ca":true},{"name":"Paria Mohseni","is_ca":true},{"name":"Ridham Desai","is_ca":true},{"name":"Maria Mileikovsky","is_ca":true},{"name":"Riikka H. Hämäläinen","is_ca":true},{"name":"Rebecca Cowling","is_ca":true},{"name":"Wei Wang","is_ca":false},{"name":"Pentao Liu","is_ca":false},{"name":"Marina Gertsenstein","is_ca":true},{"name":"Keisuke Kaji","is_ca":false},{"name":"Hoon‐Ki Sung","is_ca":true},{"name":"András Nagy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00959494755396237,"gpt":0.2683907406718712,"spread":0.2587957931179088,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004760194,0.0009621891,0.0004875008,0.0008605665,0.0002668369,0.0008069347,0.0006222228,0.001028122,0.003436717],"category_scores_gemma":[0.0004245848,0.0006844326,0.0007501231,0.0003686284,0.0006350157,0.0004548006,0.0006691375,0.001693505,0.002610022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003792867,"about_ca_system_score_gemma":0.0002947379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005253805,"about_ca_topic_score_gemma":0.0008067422,"domain_scores_codex":[0.9994791,0.0001065444,0.00005774288,0.0001340656,0.0001431307,0.00007944571],"domain_scores_gemma":[0.9993972,0.0002662465,0.00009804202,0.0001352012,0.00002897475,0.00007440741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002410328,0.000007978126,0.0000524611,0.00001215807,0.000003884807,0.0001372733,0.00001756027,0.00003096856,0.9985645,0.0002902054,0.00004786743,0.0008110176],"study_design_scores_gemma":[0.00001757256,0.00008690869,0.00119428,0.000004436951,0.00001753985,0.0004856743,0.0000232308,0.0004382218,0.994087,0.0001300763,0.003509564,0.000005621898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9283461,0.002183051,0.0429862,0.0009667674,0.001132992,0.0002722343,0.00224903,0.002360014,0.0195036],"genre_scores_gemma":[0.9589052,0.001407455,0.01150301,0.00039475,0.00008456772,0.00008849842,0.001812165,0.0009210392,0.02488331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003436717,"threshold_uncertainty_score":0.01149696,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2168967248","doi":"10.1016/j.cell.2008.02.008","title":"Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development","year":2008,"lang":"en","type":"review","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1726,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Discovery Centre; University Health Network","funders":"","keywords":"Biology; Endoderm; Embryonic stem cell; Mesoderm; Cell biology; Ectoderm; Regenerative medicine; Stem cell; Gastrulation; Cellular differentiation; Progenitor cell; Embryogenesis; Genetics; Embryo","authors":[{"name":"Charles E. Murry","is_ca":false},{"name":"Gordon Keller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08043083313625862,"gpt":0.3545807796909344,"spread":0.2741499465546757,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001575297,0.001157678,0.001474768,0.001164834,0.0003013875,0.001296495,0.001607137,0.001741738,0.001522348],"category_scores_gemma":[0.001009155,0.0003517079,0.0004054993,0.001437289,0.001719601,0.001930001,0.0008111869,0.00340359,0.001911881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001160567,"about_ca_system_score_gemma":0.000937516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000972879,"about_ca_topic_score_gemma":0.00187697,"domain_scores_codex":[0.999737,0.00004054956,0.00003356263,0.00004849945,0.0001177843,0.00002261361],"domain_scores_gemma":[0.9994175,0.0003492517,0.0000319383,0.00002776743,0.0001300823,0.00004341393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008025908,0.00005977798,0.0001925163,0.00582883,0.00005400614,0.0003828493,0.00008944032,0.0008397727,0.008519488,0.01898828,0.03188254,0.9330822],"study_design_scores_gemma":[0.00002481805,0.00005148907,0.0003493262,0.0008743547,0.00004257657,0.001250871,0.00007243665,0.0001421264,0.004654195,0.008202339,0.9843131,0.0000223364],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002378189,0.9940504,0.002401258,0.0008670017,0.0006098659,0.000006331038,0.00001998133,0.00002547003,0.001781873],"genre_scores_gemma":[0.00102839,0.9952672,0.00165822,0.0005388247,0.0002444177,0.00001107784,0.00003096294,0.000006344001,0.001214727],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001741738,"threshold_uncertainty_score":0.008420527,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2141310245","doi":"10.1038/ncb0901-778","title":"Isolation of multipotent adult stem cells from the dermis of mammalian skin","year":2001,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1598,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Killam Trusts","keywords":"Stem cell; Cell biology; Biology; Multipotent Stem Cell; Adult stem cell; Dermis; Cellular differentiation; Neurosphere; Transplantation; Neural stem cell; Progenitor cell; Anatomy; Genetics; Medicine; Gene; Internal medicine","authors":[{"name":"Jean G. Toma","is_ca":true},{"name":"Mahnaz Akhavan","is_ca":true},{"name":"Karl J. L. Fernandes","is_ca":true},{"name":"Fanie Barnabé‐Heider","is_ca":true},{"name":"Abbas F. Sadikot","is_ca":true},{"name":"David R. Kaplan","is_ca":true},{"name":"Freda D. Miller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00750351923205208,"gpt":0.2475778697411711,"spread":0.240074350509119,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001732791,0.0001884458,0.0002215099,0.0004404349,0.0002279989,0.0003927924,0.000275905,0.0002187064,0.001786441],"category_scores_gemma":[0.0001836145,0.000218727,0.0002400166,0.0002105831,0.000158387,0.0003982639,0.000483886,0.0007503905,0.001249029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009780238,"about_ca_system_score_gemma":0.0001613392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002123361,"about_ca_topic_score_gemma":0.0004163859,"domain_scores_codex":[0.9998885,0.000008585132,0.00001788562,0.000023386,0.00004607346,0.00001552248],"domain_scores_gemma":[0.9998548,0.00002654622,0.00001959489,0.00002780802,0.0000323949,0.00003885994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002018282,0.000006492476,0.000264182,0.00003048744,0.000003122905,0.00009190453,0.00002319605,0.00002926094,0.9961466,0.0002599521,0.00005614176,0.003068471],"study_design_scores_gemma":[0.00001846391,0.0001018016,0.005612,0.00002344102,0.00002695216,0.0009998783,0.00007066683,0.0005449748,0.9808725,0.0003855278,0.01133999,0.000003895726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8969573,0.008573391,0.07329761,0.0005416529,0.0002739359,0.0005201944,0.002764626,0.0003649801,0.01670636],"genre_scores_gemma":[0.9330003,0.005670717,0.04076139,0.0002953607,0.0000995062,0.000152097,0.004096296,0.0001321847,0.01579197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001786441,"threshold_uncertainty_score":0.00597626,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101569447","doi":"10.1126/science.1239278","title":"Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds","year":2013,"lang":"en","type":"article","venue":"Science","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1389,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"York University; Microsoft Research","keywords":"Reprogramming; Induced pluripotent stem cell; Somatic cell; Embryonic stem cell; Biology; Stem cell; Cell biology; Regenerative medicine; Germline; Cell potency; Cellular differentiation; Induced stem cells; Epigenetics; Genetics; Cell; Gene","authors":[{"name":"Pingping Hou","is_ca":false},{"name":"Yanqin Li","is_ca":false},{"name":"Xu Zhang","is_ca":false},{"name":"Chun Liu","is_ca":false},{"name":"Jingyang Guan","is_ca":false},{"name":"Honggang Li","is_ca":false},{"name":"Ting Zhao","is_ca":false},{"name":"Junqing Ye","is_ca":false},{"name":"Weifeng Yang","is_ca":false},{"name":"Kang Liu","is_ca":false},{"name":"Jian Ge","is_ca":false},{"name":"Jun Xu","is_ca":false},{"name":"Qiang Zhang","is_ca":false},{"name":"Yang Zhao","is_ca":false},{"name":"Hongkui Deng","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01648234363146699,"gpt":0.2381447678658764,"spread":0.2216624242344093,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003248927,0.0006060532,0.0003797048,0.0004729115,0.000174165,0.0002737397,0.0001847365,0.0002993462,0.001838402],"category_scores_gemma":[0.0002069512,0.0001665891,0.0003526976,0.0002733287,0.0002320317,0.0002105686,0.0002821686,0.0005329511,0.0006642112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001574783,"about_ca_system_score_gemma":0.0002755199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000112307,"about_ca_topic_score_gemma":0.000276194,"domain_scores_codex":[0.9998087,0.00003654778,0.00003088025,0.00002685495,0.00007531866,0.00002164406],"domain_scores_gemma":[0.9998851,0.00003351981,0.00003128633,0.00001544857,0.00001514944,0.00001960504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002559983,0.000009838359,0.00006809911,0.00005427693,0.000007049427,0.00002792991,0.000004602285,0.00007912249,0.997085,0.0001647919,0.00005118231,0.00242258],"study_design_scores_gemma":[0.00001436343,0.0002196293,0.0003618534,0.000004967875,0.00001869646,0.00009030725,0.000003420021,0.0001394507,0.996192,0.00005012024,0.002901742,0.00000360767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8720683,0.01323476,0.09155976,0.0006701898,0.0003542566,0.001118771,0.003535603,0.001207505,0.01625079],"genre_scores_gemma":[0.9494739,0.007583999,0.03377123,0.0002676108,0.00006279601,0.0005085117,0.002222721,0.0001075838,0.006001594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001838402,"threshold_uncertainty_score":0.006150126,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2106485710","doi":"10.1038/nature07864","title":"Virus-free induction of pluripotency and subsequent excision of reprogramming factors","year":2009,"lang":"en","type":"article","venue":"Nature","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1234,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Reprogramming; Induced pluripotent stem cell; Biology; Regenerative medicine; Somatic cell; Cell biology; Viral vector; Embryonic stem cell; Stem cell; Genetics; Cell; Gene","authors":[{"name":"Keisuke Kaji","is_ca":false},{"name":"Katherine Norrby","is_ca":false},{"name":"Agnieszka Paca","is_ca":false},{"name":"Maria Mileikovsky","is_ca":true},{"name":"Paria Mohseni","is_ca":true},{"name":"Knut Woltjen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01242602262429036,"gpt":0.281171653684511,"spread":0.2687456310602206,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005651235,0.0006040864,0.0003926011,0.0005869139,0.0003254538,0.0007113697,0.0007171736,0.0005862528,0.002282519],"category_scores_gemma":[0.0004149104,0.0004500892,0.0007992751,0.0003624804,0.0004369042,0.0004779556,0.0006716967,0.001407015,0.001050472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000603943,"about_ca_system_score_gemma":0.0005405959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006687986,"about_ca_topic_score_gemma":0.001292502,"domain_scores_codex":[0.9995379,0.00006712,0.00005514426,0.00008494089,0.0001318375,0.000123055],"domain_scores_gemma":[0.9996852,0.00009959081,0.00004353062,0.00009467715,0.00002801792,0.00004904344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006498227,0.00002318707,0.00007172906,0.00003059937,0.00001008813,0.00003176683,0.00002280529,0.00005721657,0.9968687,0.001246599,0.00006446936,0.001507879],"study_design_scores_gemma":[0.00001037845,0.0000392106,0.0005555495,0.00000320766,0.00001060553,0.00007881028,0.000006914321,0.0001892271,0.9957939,0.0001417656,0.003165885,0.000004522504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8901596,0.004166503,0.08657114,0.0004121104,0.0006187806,0.0006020128,0.003280015,0.0007999807,0.01338988],"genre_scores_gemma":[0.9514643,0.001277718,0.02313501,0.0001610132,0.00005249405,0.0002328582,0.004563973,0.0003044772,0.01880806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002282519,"threshold_uncertainty_score":0.007635832,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2123829995","doi":"10.1016/j.cell.2005.08.040","title":"Interaction between Oct3/4 and Cdx2 Determines Trophectoderm Differentiation","year":2005,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1205,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Core Research for Evolutional Science and Technology; RIKEN; Japan Science and Technology Agency; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Biology; Psychological repression; Homeobox; CDX2; Trophoblast; Cellular differentiation; Embryonic stem cell; Transcription factor; Inner cell mass; Cell biology; Stem cell; Genetics; Lineage (genetic); Embryogenesis; Gene; Embryo; Placenta; Blastocyst; Gene expression","authors":[{"name":"Hitoshi Niwa","is_ca":false},{"name":"Yayoi Toyooka","is_ca":false},{"name":"Daisuke Shimosato","is_ca":false},{"name":"Dan Strumpf","is_ca":true},{"name":"Kadue Takahashi","is_ca":false},{"name":"Rika Yagi","is_ca":false},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0143555077617401,"gpt":0.2688909392031481,"spread":0.254535431441408,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001948052,0.0002426993,0.0001929915,0.0003622466,0.000431425,0.0008792568,0.0003244139,0.0003613414,0.002728306],"category_scores_gemma":[0.0003023931,0.0004387703,0.0002278034,0.0002006392,0.000372586,0.0004939335,0.0005949124,0.0007845606,0.0008495702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008851899,"about_ca_system_score_gemma":0.0003740594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001646858,"about_ca_topic_score_gemma":0.00415566,"domain_scores_codex":[0.9997402,0.00004784113,0.00001979482,0.00004477945,0.00005465683,0.00009273698],"domain_scores_gemma":[0.9997095,0.00009352654,0.00005393351,0.00002891551,0.00002197206,0.0000920445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001103691,0.000008111028,0.0004725131,0.000007849193,0.000002973382,0.00005887479,0.000009129047,0.00003893372,0.9985996,0.0002950392,0.00002970215,0.0003669949],"study_design_scores_gemma":[0.0000157088,0.00003568084,0.01076531,0.000003459326,0.00001108069,0.0002986717,0.00007263677,0.001035018,0.9856102,0.0001128453,0.00203442,0.000005009825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933118,0.0008919213,0.001989049,0.00009956029,0.0000276029,0.000009983977,0.000168063,0.0000424386,0.003459585],"genre_scores_gemma":[0.9903151,0.0003367817,0.001615655,0.00007084417,0.0000109534,0.00001408619,0.0005389723,0.00005860342,0.007038875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002728306,"threshold_uncertainty_score":0.00912714,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1977025496","doi":"10.1016/j.stem.2010.12.008","title":"Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines","year":2011,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1176,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Mesoderm; Nodal signaling; NODAL; Induced pluripotent stem cell; Embryonic stem cell; Cell biology; Stem cell; Cellular differentiation; Activin receptor; Signal transduction; Genetics; Gene","authors":[{"name":"Steven Kattman","is_ca":true},{"name":"Alec Witty","is_ca":true},{"name":"Mark Gagliardi","is_ca":true},{"name":"Nicole Dubois","is_ca":true},{"name":"Maryam Niapour","is_ca":true},{"name":"Akitsu Hotta","is_ca":true},{"name":"James Ellis","is_ca":true},{"name":"Gordon Keller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0232745422932977,"gpt":0.2244167893300289,"spread":0.2011422470367312,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004195519,0.000368976,0.0003008581,0.0004983038,0.000149336,0.0003840202,0.0002985374,0.0002428079,0.001919808],"category_scores_gemma":[0.0002173257,0.0002916644,0.0003794866,0.0002810969,0.0001948988,0.0001853461,0.0002439217,0.0006714368,0.0004600506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002884917,"about_ca_system_score_gemma":0.0002622456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000706099,"about_ca_topic_score_gemma":0.001886731,"domain_scores_codex":[0.9997136,0.00004343479,0.00006058245,0.00004988402,0.00007734836,0.00005516321],"domain_scores_gemma":[0.999819,0.00006073792,0.00003825432,0.00002394052,0.00001604821,0.00004204514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009914807,0.00001902173,0.00006971609,0.00001150363,0.000003885396,0.00001834753,0.00001034777,0.00007609033,0.9989628,0.0001282525,0.00003113012,0.0005696112],"study_design_scores_gemma":[0.00001414496,0.00007871623,0.0007578637,0.000002375026,0.00001333908,0.00005175656,0.000005956482,0.000341414,0.9971813,0.00001924058,0.001531797,0.000002176854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788308,0.001755901,0.01239536,0.0001369535,0.00007011376,0.0001771963,0.002108039,0.000193339,0.004332292],"genre_scores_gemma":[0.9774516,0.001212419,0.01058022,0.0001126403,0.00002455306,0.000152014,0.002800244,0.0002181019,0.007448117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001919808,"threshold_uncertainty_score":0.0064224,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1994144105","doi":"10.1242/dev.01801","title":"Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst","year":2005,"lang":"en","type":"article","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1141,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Synchrotron Light Research Institute; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Inner cell mass; Biology; Blastocyst; Homeobox protein NANOG; Cell biology; Trophoblast; Blastocoel; Nanog Homeobox Protein; Embryo; Embryonic stem cell; CDX2; Transcription factor; Genetics; Homeobox; Embryogenesis; SOX2; Placenta; Gene; Induced pluripotent stem cell","authors":[{"name":"Dan Strumpf","is_ca":true},{"name":"Chai‐An Mao","is_ca":true},{"name":"Yojiro Yamanaka","is_ca":true},{"name":"Amy Ralston","is_ca":true},{"name":"Kallayanee Chawengsaksophak","is_ca":true},{"name":"Felix Beck","is_ca":false},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02148918862219947,"gpt":0.2563346981636353,"spread":0.2348455095414358,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001409684,0.0004828962,0.0002233282,0.0002944149,0.000269836,0.0005525129,0.0002247798,0.0003756238,0.001913809],"category_scores_gemma":[0.0001962318,0.000389745,0.0001424688,0.0001409132,0.0002920793,0.0002349597,0.0003966229,0.0004445113,0.0009494757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003473255,"about_ca_system_score_gemma":0.0002830334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006030297,"about_ca_topic_score_gemma":0.0009615609,"domain_scores_codex":[0.9997606,0.00002514542,0.00003002824,0.00005838038,0.00008170116,0.00004412456],"domain_scores_gemma":[0.9998018,0.00002245122,0.00006008494,0.00002391345,0.00001854258,0.00007314865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007048068,0.00001176431,0.0003948282,0.00002569881,0.000002945539,0.0001554425,0.000009646011,0.00005160481,0.9984804,0.0001380936,0.00004111259,0.0006178968],"study_design_scores_gemma":[0.00005042106,0.0000834024,0.01722095,0.00001230562,0.00001592744,0.0008173261,0.00003312861,0.0008961675,0.9758369,0.0001000004,0.00492762,0.000005947904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890428,0.001706872,0.003505941,0.0001550422,0.00004901437,0.00002496969,0.001011902,0.0001832633,0.004320185],"genre_scores_gemma":[0.9840267,0.0007352751,0.002020279,0.00006129744,0.00001321897,0.00003883386,0.001939357,0.00009093885,0.01107413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001913809,"threshold_uncertainty_score":0.006402373,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2010672807","doi":"10.1016/j.stem.2010.04.015","title":"Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming","year":2010,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1009,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Reprogramming; Biology; Somatic cell; Mesenchymal stem cell; Cell biology; Epithelial–mesenchymal transition; Genomics; Functional genomics; Transition (genetics); Cell; Computational biology; Genome; Genetics; Evolutionary biology; Gene","authors":[{"name":"Payman Samavarchi‐Tehrani","is_ca":true},{"name":"Azadeh Golipour","is_ca":true},{"name":"Laurent David","is_ca":true},{"name":"Hoon‐Ki Sung","is_ca":true},{"name":"Tobias A. Beyer","is_ca":true},{"name":"Alessandro Datti","is_ca":true},{"name":"Knut Woltjen","is_ca":true},{"name":"András Nagy","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01471190987219746,"gpt":0.2374418828061,"spread":0.2227299729339026,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001876897,0.0002952162,0.0001921201,0.0002667918,0.0001696843,0.0004554301,0.0003392672,0.0003715175,0.0009492831],"category_scores_gemma":[0.0001611856,0.0002496325,0.0002663953,0.0001245894,0.0003205198,0.0002080929,0.000303519,0.0009491501,0.0006551463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004194709,"about_ca_system_score_gemma":0.0002920915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007000083,"about_ca_topic_score_gemma":0.0008852236,"domain_scores_codex":[0.9998146,0.00002127875,0.00001231898,0.00003737053,0.00007664724,0.00003785419],"domain_scores_gemma":[0.9998746,0.00003555817,0.00002848259,0.00001285405,0.00001500631,0.00003347327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002847205,0.00000631784,0.00005940308,0.00000688575,0.000001350219,0.00002429169,0.000004941236,0.00008579624,0.9985644,0.0005802729,0.00001356766,0.0006243553],"study_design_scores_gemma":[0.000008320279,0.00003058459,0.001177897,0.000002652543,0.000007835748,0.00009937497,0.00001025357,0.00122766,0.9962275,0.0001809072,0.00102379,0.000003322145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9519823,0.0006133954,0.0405155,0.0003935139,0.00006795526,0.00007726734,0.0008299203,0.0003367453,0.005183316],"genre_scores_gemma":[0.9866982,0.0003361986,0.008576273,0.0001059105,0.00001333121,0.00002771894,0.0004630774,0.0001055436,0.003673682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009492831,"threshold_uncertainty_score":0.003175676,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2086663462","doi":"10.1038/nature09871","title":"Copy number variation and selection during reprogramming to pluripotency","year":2011,"lang":"en","type":"article","venue":"Nature","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":949,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto; Ontario Institute for Cancer Research; Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Reprogramming; Induced pluripotent stem cell; Biology; Copy-number variation; Embryonic stem cell; Somatic cell; Genetics; Cell biology; Cell; Genome; Gene","authors":[{"name":"Samer M. I. Hussein","is_ca":true},{"name":"Nizar N. Batada","is_ca":true},{"name":"Sanna Vuoristo","is_ca":false},{"name":"Reagan W. Ching","is_ca":true},{"name":"Reija Autio","is_ca":false},{"name":"Elisa Närvä","is_ca":false},{"name":"Siemon H. S. Ng","is_ca":true},{"name":"Michel Sourour","is_ca":true},{"name":"Riikka H. Hämäläinen","is_ca":true},{"name":"Cia Olsson","is_ca":false},{"name":"Karolina Lundin","is_ca":false},{"name":"Milla Mikkola","is_ca":false},{"name":"Ras Trokovic","is_ca":false},{"name":"Michael Peitz","is_ca":false},{"name":"Oliver Brüstle","is_ca":false},{"name":"David P. Bazett‐Jones","is_ca":true},{"name":"Kari Alitalo","is_ca":false},{"name":"Riitta Lahesmaa","is_ca":false},{"name":"András Nagy","is_ca":true},{"name":"Timo Otonkoski","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008863039891250939,"gpt":0.2643158256502704,"spread":0.2554527857590195,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005258682,0.0001687218,0.0002503326,0.0004694059,0.0002301619,0.0007564281,0.0005703502,0.0003406191,0.001536297],"category_scores_gemma":[0.001300415,0.0003062314,0.0002078399,0.0004045046,0.0003400205,0.0005199047,0.000611692,0.0007045325,0.0004634221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005675561,"about_ca_system_score_gemma":0.000212133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000635306,"about_ca_topic_score_gemma":0.002180075,"domain_scores_codex":[0.9993481,0.0001414973,0.00004816524,0.0001343411,0.0002392359,0.00008876296],"domain_scores_gemma":[0.9992825,0.000377579,0.0001097331,0.0001008673,0.00006209006,0.00006723353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007746398,0.000008636083,0.001640888,0.000008546736,0.000006236346,0.00007341589,0.00003107332,0.0002671966,0.991935,0.000499468,0.00004555636,0.005406456],"study_design_scores_gemma":[0.00001420017,0.0001402606,0.02624013,0.0000064853,0.00002764992,0.0009610197,0.00007443618,0.007658619,0.9608069,0.0009180891,0.00312168,0.00003060018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864922,0.0005410882,0.009687152,0.0001425815,0.00002334681,0.00002039871,0.0001911892,0.00009281811,0.002809177],"genre_scores_gemma":[0.9933299,0.0002747331,0.003224184,0.00008111389,0.00001225915,0.00001653193,0.0002428438,0.0001663083,0.002651951],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001536297,"threshold_uncertainty_score":0.00513947,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2110737932","doi":"10.1016/j.devcel.2006.02.020","title":"Early Lineage Segregation between Epiblast and Primitive Endoderm in Mouse Blastocysts through the Grb2-MAPK Pathway","year":2006,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":920,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Epiblast; Endoderm; Lineage (genetic); Cell biology; Gastrulation; Embryo; Genetics; Embryonic stem cell; Embryogenesis; Gene","authors":[{"name":"Claire Chazaud","is_ca":true},{"name":"Yojiro Yamanaka","is_ca":true},{"name":"Tony Pawson","is_ca":true},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01079506560167067,"gpt":0.2237132121451958,"spread":0.2129181465435251,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002554235,0.000332065,0.000252716,0.000576456,0.0002791947,0.0005061849,0.0003629356,0.0003387005,0.001662225],"category_scores_gemma":[0.0001801042,0.0004750068,0.000217265,0.0001824885,0.0002201758,0.0004507283,0.0005778042,0.0008735745,0.0009075752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003717214,"about_ca_system_score_gemma":0.0003218993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007608362,"about_ca_topic_score_gemma":0.001676001,"domain_scores_codex":[0.9998087,0.00002412868,0.00001915461,0.00003887306,0.00006195816,0.00004715983],"domain_scores_gemma":[0.9997992,0.00003354725,0.00005231884,0.00002535309,0.00002694348,0.00006265694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001676717,0.000008355584,0.0004180678,0.00002128584,0.000003100551,0.0001004892,0.00002391577,0.00008071242,0.9972313,0.0006727579,0.00005005898,0.001222384],"study_design_scores_gemma":[0.00003322943,0.00006824931,0.009735567,0.00001417542,0.0000136317,0.0004313863,0.00005241401,0.001127597,0.984983,0.0001890441,0.00334671,0.00000494228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986497,0.001607926,0.006238417,0.0001011411,0.00003664167,0.00002854715,0.0005321764,0.0001400133,0.004818147],"genre_scores_gemma":[0.9798256,0.0007130227,0.00413942,0.00007394431,0.00001530757,0.00004596547,0.000866292,0.0001076011,0.01421292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001662225,"threshold_uncertainty_score":0.005560696,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2018765068","doi":"10.1242/dev.02880","title":"FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment","year":2007,"lang":"en","type":"article","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":805,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"Directorate for Biological Sciences; European Commission; National Cancer Institute; Medical Research Council; Parkinson's UK","keywords":"Biology; Cell biology; Embryonic stem cell; Fibroblast growth factor; MAPK/ERK pathway; Germ layer; Homeobox protein NANOG; Neural crest; Stem cell; Cellular differentiation; Rex1; Induced pluripotent stem cell; Signal transduction; Genetics; Embryo; Receptor","authors":[{"name":"Tilo Kunath","is_ca":false},{"name":"Marc K. Saba-El-Leil","is_ca":true},{"name":"Marwa Almousailleakh","is_ca":false},{"name":"Jason Wray","is_ca":false},{"name":"Sylvain Meloche","is_ca":true},{"name":"Austin Smith","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01495233133731103,"gpt":0.2472218426390307,"spread":0.2322695113017196,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006749492,0.0003362167,0.0001201477,0.0001426741,0.0000912999,0.0001561718,0.0001129809,0.0001131133,0.001688689],"category_scores_gemma":[0.00007799119,0.0001208016,0.0001728451,0.00006976325,0.0001091637,0.0001240053,0.0002078686,0.0002568832,0.0002917142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001603121,"about_ca_system_score_gemma":0.000128887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001989294,"about_ca_topic_score_gemma":0.0004270265,"domain_scores_codex":[0.9999188,0.00001368107,0.000007326092,0.00001141734,0.00002951275,0.00001926896],"domain_scores_gemma":[0.9999706,0.000008663803,0.000006754279,0.000003191965,0.000004228086,0.00000658584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004357116,0.000007330873,0.0001619866,0.00003108668,0.00000248294,0.00003907806,0.000004958794,0.00006466466,0.9984333,0.00009485087,0.00001934324,0.001097348],"study_design_scores_gemma":[0.000006920512,0.00006233945,0.00365455,0.000003866817,0.000006458832,0.0001654911,0.00001018989,0.0007771348,0.9937149,0.00007962016,0.001516161,0.000002493393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917983,0.001170496,0.003745155,0.00007608209,0.00002350534,0.00002842406,0.0003348775,0.0000792237,0.002743877],"genre_scores_gemma":[0.9938276,0.0008092874,0.002326881,0.00003179724,0.000008971048,0.00003018198,0.0003396611,0.00001137027,0.002614154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001688689,"threshold_uncertainty_score":0.005649209,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2097812689","doi":"10.1096/fj.01-0995fje","title":"Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells","year":2002,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":792,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; American Heart Association","keywords":"HEK 293 cells; Embryonic stem cell; Cell culture; Cell biology; Biology; Molecular biology; Transfection; Genetics; Gene","authors":[{"name":"Gerry Shaw","is_ca":false},{"name":"Silas Morse","is_ca":false},{"name":"Miguel Ararat","is_ca":false},{"name":"Frank L. Graham","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02637467796671785,"gpt":0.2661869472529805,"spread":0.2398122692862627,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008908618,0.0002673566,0.0004134201,0.0003012725,0.0002786623,0.0007987391,0.0004001248,0.0003037697,0.002210008],"category_scores_gemma":[0.0006912671,0.0002753382,0.0003305877,0.0004129896,0.0002711104,0.0003325545,0.0004442512,0.0009262419,0.001611863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003627019,"about_ca_system_score_gemma":0.0003775481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006270446,"about_ca_topic_score_gemma":0.001258181,"domain_scores_codex":[0.9991335,0.0001729663,0.0001893042,0.0001746183,0.0002255317,0.0001040819],"domain_scores_gemma":[0.9995973,0.0001226144,0.00004436345,0.0001268581,0.00008053595,0.00002844079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002393892,0.00006135695,0.0007281313,0.00009345677,0.00001621024,0.0001520044,0.0001194859,0.00012634,0.990962,0.002174231,0.0002611412,0.005066399],"study_design_scores_gemma":[0.00003491014,0.0001757888,0.002106329,0.00001877655,0.0000384697,0.001066163,0.00008887411,0.001445921,0.972578,0.0003254121,0.0221078,0.00001355571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7664669,0.005669596,0.2055915,0.0005164193,0.0007978171,0.001096275,0.004637119,0.0006437794,0.01458062],"genre_scores_gemma":[0.8749655,0.003515902,0.1049628,0.000183304,0.00005107961,0.0004610667,0.005711569,0.0001533462,0.009995364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002210008,"threshold_uncertainty_score":0.007393241,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1989920563","doi":"10.1016/s0896-6273(01)00263-x","title":"Direct Neural Fate Specification from Embryonic Stem Cells","year":2001,"lang":"en","type":"article","venue":"Neuron","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":759,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Amgen (Canada); Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Neural stem cell; Embryonic stem cell; Neural cell; Biology; Stem cell; Neural development; Precursor cell; Neuroscience; Cell biology; Cell; Genetics; Gene","authors":[{"name":"Vincent Tropepe","is_ca":true},{"name":"Seiji Hitoshi","is_ca":true},{"name":"Christian Sirard","is_ca":true},{"name":"Tak W. Mak","is_ca":true},{"name":"Janet Rossant","is_ca":true},{"name":"Derek van der Kooy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02400905668904593,"gpt":0.2554025714427481,"spread":0.2313935147537022,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003932111,0.000449118,0.0003003677,0.0004745522,0.0002809729,0.0007225058,0.0003564667,0.0003394495,0.002653087],"category_scores_gemma":[0.0003617206,0.0003457827,0.0003586846,0.0002741325,0.0002855225,0.0002992101,0.0006864713,0.0009962469,0.002039737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000374606,"about_ca_system_score_gemma":0.000452149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006980135,"about_ca_topic_score_gemma":0.002290081,"domain_scores_codex":[0.9997733,0.0000323377,0.00002176876,0.00003867105,0.00009508311,0.00003873213],"domain_scores_gemma":[0.9997588,0.0001030595,0.00002609086,0.00003860358,0.0000366742,0.00003677527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006611649,0.00001577735,0.000162098,0.0000815629,0.000008661628,0.00009855595,0.00004257889,0.00008983974,0.9903659,0.002283132,0.0002661899,0.006519713],"study_design_scores_gemma":[0.0000217538,0.00004421789,0.001095345,0.0000133927,0.00001415091,0.0001846912,0.00002643672,0.0002812447,0.9848115,0.0005595359,0.01294409,0.000003612794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8209403,0.01533847,0.09223301,0.001332634,0.0006999812,0.0003056682,0.002915554,0.0005804864,0.06565388],"genre_scores_gemma":[0.9232525,0.009156164,0.02199539,0.0003704153,0.0001268295,0.000140878,0.002955279,0.0002826065,0.04171995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002653087,"threshold_uncertainty_score":0.008875489,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2083763893","doi":"10.1016/j.ydbio.2003.12.034","title":"Differences between human and mouse embryonic stem cells","year":2004,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":715,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials; Western University","funders":"National Institute of Neurological Disorders and Stroke; Johns Hopkins University","keywords":"Biology; Lineage markers; Molecular biology; Embryonic stem cell; Stem cell marker; Stem cell; Cell biology; Cellular differentiation; Gene expression; Cell culture; Vimentin; Progenitor cell; Gene; Immunology; Genetics; Immunohistochemistry","authors":[{"name":"Irene Ginis","is_ca":false},{"name":"Yongquan Luo","is_ca":false},{"name":"Takumi Miura","is_ca":false},{"name":"Scott Thies","is_ca":false},{"name":"Ralph Brandenberger","is_ca":false},{"name":"Sharon Gerecht‐Nir","is_ca":false},{"name":"Michal Amit","is_ca":false},{"name":"Ahmet Höke","is_ca":false},{"name":"Melissa K. Carpenter","is_ca":true},{"name":"Joseph Itskovitz‐Eldor","is_ca":false},{"name":"Mahendra S. Rao","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02437748015418677,"gpt":0.2684794241863813,"spread":0.2441019440321945,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000517184,0.0001176337,0.000225863,0.0005190654,0.000161213,0.0007916964,0.0002526064,0.0002413471,0.003062601],"category_scores_gemma":[0.0006477016,0.0001052129,0.0002108179,0.0002968549,0.0002035131,0.0002871011,0.0002673612,0.0002638263,0.0008515928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001892018,"about_ca_system_score_gemma":0.0001888873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005538978,"about_ca_topic_score_gemma":0.0006683975,"domain_scores_codex":[0.9996786,0.00006548178,0.00003843928,0.00005368451,0.0001172691,0.00004646858],"domain_scores_gemma":[0.9996065,0.0001690263,0.00004052552,0.00004416824,0.00007955432,0.00006014584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003849304,0.00001761363,0.003530419,0.0001116563,0.00003143672,0.0001146022,0.0003601779,0.00009034985,0.9758694,0.003751695,0.0002790351,0.01545884],"study_design_scores_gemma":[0.00006715874,0.0008241141,0.1373227,0.00008855195,0.0001980161,0.004383159,0.000804451,0.0005504284,0.7875623,0.003169373,0.06499422,0.00003557418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634645,0.01080466,0.00770723,0.0002278999,0.0001475234,0.00003710641,0.001922439,0.0001257474,0.01556295],"genre_scores_gemma":[0.9835675,0.004009028,0.002327353,0.0002156544,0.00003957255,0.00004429984,0.003262583,0.00007216405,0.006461841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003062601,"threshold_uncertainty_score":0.01024544,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2125734502","doi":"10.1016/j.stem.2008.03.021","title":"Global Transcription in Pluripotent Embryonic Stem Cells","year":2008,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":698,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"Biology; Embryonic stem cell; Induced pluripotent stem cell; Chromatin; Gene silencing; Transcription (linguistics); Genome; Genetics; Transcription factor; Cellular differentiation; Cell biology; Gene; Epigenetics; Stem cell","authors":[{"name":"Sol Efroni","is_ca":false},{"name":"Radharani Duttagupta","is_ca":false},{"name":"Jill Cheng","is_ca":false},{"name":"Hesam Dehghani","is_ca":true},{"name":"Daniel J. Hoeppner","is_ca":false},{"name":"Chandravanu Dash","is_ca":false},{"name":"David P. Bazett‐Jones","is_ca":true},{"name":"Stuart Le Grice","is_ca":false},{"name":"Ronald D.G. McKay","is_ca":false},{"name":"Kenneth H. Buetow","is_ca":false},{"name":"T Gingeras","is_ca":false},{"name":"Tom Misteli","is_ca":false},{"name":"Eran Meshorer","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01661325676862228,"gpt":0.2299017340087323,"spread":0.21328847724011,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004433651,0.0004424959,0.000466548,0.0005420803,0.0002811537,0.001065938,0.0003958271,0.0003342592,0.002323894],"category_scores_gemma":[0.0003693344,0.0004236884,0.0004312729,0.0003917046,0.0006565906,0.000775779,0.0006956642,0.0009128412,0.0008579359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007892532,"about_ca_system_score_gemma":0.0003484003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006662069,"about_ca_topic_score_gemma":0.001288679,"domain_scores_codex":[0.9997186,0.00003674561,0.00001884918,0.0001201484,0.00006304249,0.00004262614],"domain_scores_gemma":[0.999774,0.00006458498,0.00003085916,0.0000488501,0.00003116934,0.00005039794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001923814,0.000010559,0.001030884,0.0001018573,0.00001183367,0.00006668916,0.00008565727,0.0004386397,0.9832643,0.00504513,0.0002922682,0.009459882],"study_design_scores_gemma":[0.00004867243,0.0002204348,0.01692134,0.00003956939,0.00005975158,0.0003930815,0.000150001,0.002109655,0.9598089,0.00539171,0.01483227,0.00002470907],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8503045,0.02882653,0.08772529,0.001805744,0.0004666833,0.0000769933,0.005176743,0.001397403,0.02422008],"genre_scores_gemma":[0.9726293,0.003691438,0.007610839,0.0002788545,0.0001079799,0.0000490643,0.003208162,0.0002880736,0.0121364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002323894,"threshold_uncertainty_score":0.007774234,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2058553784","doi":"10.1038/nature09591","title":"Direct conversion of human fibroblasts to multilineage blood progenitors","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":690,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Reprogramming; Haematopoiesis; Embryonic stem cell; Biology; Cell biology; Induced pluripotent stem cell; Stem cell; Progenitor cell; Embryoid body; Cellular differentiation; Immunology; Cell; Genetics","authors":[{"name":"Éva Szabó","is_ca":true},{"name":"Shravanti Rampalli","is_ca":true},{"name":"Ruth M. Risueño","is_ca":true},{"name":"Angelique Schnerch","is_ca":true},{"name":"Ryan R. Mitchell","is_ca":true},{"name":"Aline Fiebig‐Comyn","is_ca":true},{"name":"Marilyne Levadoux‐Martin","is_ca":true},{"name":"Mickie Bhatia","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005194584906254189,"gpt":0.2783124998269453,"spread":0.2731179149206911,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002951836,0.000317782,0.0001884448,0.0003129761,0.0001754675,0.0004362296,0.0002598461,0.0002544925,0.002135523],"category_scores_gemma":[0.0002240375,0.0001855023,0.0003516588,0.0001603628,0.0001393419,0.0001308541,0.0003154333,0.0006560507,0.001014097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001466202,"about_ca_system_score_gemma":0.0001996429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005853036,"about_ca_topic_score_gemma":0.001028049,"domain_scores_codex":[0.9998125,0.00002689034,0.00002320897,0.00004078207,0.00006143017,0.00003516942],"domain_scores_gemma":[0.9998503,0.00005805687,0.00001093576,0.00003947714,0.00001491325,0.0000263475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000923027,0.00002715701,0.0001641452,0.00003180986,0.000008661626,0.000124847,0.00006000474,0.00008526906,0.9950177,0.0005140144,0.0001013352,0.003772742],"study_design_scores_gemma":[0.0000142738,0.00006687223,0.0009043986,0.000003619991,0.00001232715,0.0001963099,0.00001557776,0.0001928669,0.9938207,0.0001012404,0.004669732,0.000002137368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9459572,0.00253193,0.02754707,0.0002304368,0.0003055195,0.0003134482,0.002462714,0.000315482,0.02033616],"genre_scores_gemma":[0.9697212,0.001332686,0.008449049,0.00009781098,0.00003205433,0.00009183209,0.002036598,0.00007920106,0.01815971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002135523,"threshold_uncertainty_score":0.007144034,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1964324925","doi":"10.1016/j.stem.2012.10.002","title":"Metabolic Plasticity in Stem Cell Homeostasis and Differentiation","year":2012,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":680,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Biology; Stem cell; Homeostasis; Plasticity; Cell biology; Cellular differentiation; Evolutionary biology; Genetics; Gene","authors":[{"name":"Clifford D.L. Folmes","is_ca":false},{"name":"Petras P. Dzeja","is_ca":false},{"name":"Timothy J. Nelson","is_ca":false},{"name":"André Terzic","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01439803935334645,"gpt":0.2324134839482978,"spread":0.2180154445949514,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001817382,0.0002618319,0.000255488,0.0004848278,0.0003899548,0.001212977,0.0004108854,0.0004806827,0.001382162],"category_scores_gemma":[0.0001960478,0.0001942124,0.0002478902,0.0004587976,0.0006301695,0.001306239,0.0005231909,0.0005422514,0.0003874061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006595083,"about_ca_system_score_gemma":0.0002590029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005674847,"about_ca_topic_score_gemma":0.0008463628,"domain_scores_codex":[0.9998769,0.00002278982,0.000009703052,0.00002951602,0.00003002509,0.00003114954],"domain_scores_gemma":[0.9999058,0.0000162414,0.00002035226,0.00001613567,0.0000157488,0.00002566056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005980557,0.00004090037,0.002062766,0.0002119037,0.000033276,0.0004181814,0.0001159957,0.001486137,0.9061727,0.04323893,0.0005998217,0.04502143],"study_design_scores_gemma":[0.00003456956,0.0002859124,0.02068204,0.00004590798,0.00004877619,0.001436717,0.0005830154,0.004523588,0.8981006,0.03918914,0.03500828,0.00006135445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8764724,0.05697294,0.03640304,0.004693521,0.0005558592,0.00003679373,0.0007931961,0.000271576,0.02380075],"genre_scores_gemma":[0.9865341,0.007890932,0.001964383,0.000132191,0.00007613825,0.00001369373,0.0001576329,0.00003719171,0.003193767],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001382162,"threshold_uncertainty_score":0.00478512,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2062298134","doi":"10.1016/j.stem.2011.12.013","title":"Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming","year":2012,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":674,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health","keywords":"Induced pluripotent stem cell; Reprogramming; Biology; Drug discovery; Progenitor cell; Stem cell; Cell biology; Myocyte; Cell; Bioinformatics; Embryonic stem cell; Genetics","authors":[{"name":"Paul W. Burridge","is_ca":false},{"name":"Gordon Keller","is_ca":true},{"name":"Joseph Gold","is_ca":false},{"name":"Joseph C. Wu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01594541523999913,"gpt":0.2446800585105596,"spread":0.2287346432705605,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007145848,0.0004094318,0.0004206193,0.0004063091,0.0001404111,0.0003843467,0.0003474963,0.0004167821,0.002339144],"category_scores_gemma":[0.0003947338,0.0002916483,0.0003576277,0.0002361754,0.0002010268,0.0003450715,0.0006480227,0.0008952658,0.001171098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001855959,"about_ca_system_score_gemma":0.0002789177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000119501,"about_ca_topic_score_gemma":0.0002742799,"domain_scores_codex":[0.9997,0.00004841882,0.00003185174,0.00007151062,0.0001072763,0.00004109072],"domain_scores_gemma":[0.9997894,0.00006229545,0.00002952062,0.00004578268,0.00002847386,0.00004451176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009192746,0.00003886322,0.0003218436,0.0001162606,0.00001429335,0.0001697324,0.00004740878,0.0002222328,0.9800918,0.00188367,0.0002322293,0.01676975],"study_design_scores_gemma":[0.00004073258,0.0001337831,0.0009175566,0.000009983538,0.00002179518,0.0004570481,0.00001483986,0.0005489221,0.9902377,0.0005129118,0.007098423,0.000006254776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6175687,0.01105154,0.3252885,0.000959951,0.001020067,0.0008887973,0.003220378,0.001189802,0.03881218],"genre_scores_gemma":[0.8708599,0.006469527,0.09943592,0.0003546021,0.0001768782,0.0002908561,0.0024736,0.0002934024,0.0196453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002339144,"threshold_uncertainty_score":0.007825255,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2077765163","doi":"10.1242/dev.017178","title":"Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse","year":2009,"lang":"en","type":"review","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":645,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Biology; Blastocyst; Embryo; Endoderm; Lineage (genetic); Gastrulation; Cell biology; Embryonic stem cell; Inner cell mass; Embryogenesis; Epiblast; Genetics; Gene","authors":[{"name":"Janet Rossant","is_ca":true},{"name":"Patrick Tam","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03124408196822149,"gpt":0.2985749037369061,"spread":0.2673308217686846,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004017734,0.0007606333,0.0009185033,0.001841878,0.0002996969,0.0007611815,0.0008415166,0.001014681,0.002139147],"category_scores_gemma":[0.0003561031,0.0003328695,0.0002044112,0.00202591,0.0007503583,0.001062982,0.0004529747,0.0009007581,0.002488017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006097616,"about_ca_system_score_gemma":0.0007221376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001334382,"about_ca_topic_score_gemma":0.001970455,"domain_scores_codex":[0.9998921,0.00001194661,0.00001635081,0.0000266221,0.00004576219,0.000007254807],"domain_scores_gemma":[0.9998953,0.00003401096,0.00002416762,0.000005557026,0.00002479715,0.00001609143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007867081,0.00004362767,0.0002506836,0.008326817,0.00003901915,0.0004355341,0.0001022588,0.000646794,0.01232623,0.01024887,0.01469621,0.9528053],"study_design_scores_gemma":[0.000009664956,0.00006605365,0.001287654,0.0009989126,0.00004758914,0.001447082,0.00005345522,0.00007129432,0.002227808,0.00321943,0.9905576,0.00001347454],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000316495,0.9968862,0.0004122444,0.0001450194,0.0001174527,0.000004854245,0.00002178856,0.00001410039,0.002081787],"genre_scores_gemma":[0.001058776,0.9967722,0.0003731038,0.0001072668,0.00006806164,0.000007492684,0.00003078846,0.000002298878,0.001579944],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002139147,"threshold_uncertainty_score":0.007156193,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2166791809","doi":"10.1016/j.stem.2011.07.014","title":"Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons","year":2011,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":640,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institute of Neurological Disorders and Stroke; Howard Hughes Medical Institute","keywords":"Biology; Reprogramming; Motor neuron; Embryonic stem cell; Neuroscience; Transcription factor; Progenitor cell; Cell biology; Phenotype; Nervous system; Anatomy; Stem cell; Spinal cord; Cell; Gene; Genetics","authors":[{"name":"Esther Son","is_ca":false},{"name":"Justin K. Ichida","is_ca":false},{"name":"Brian J. Wainger","is_ca":false},{"name":"Jeremy S. Toma","is_ca":true},{"name":"Victor F. Rafuse","is_ca":true},{"name":"Clifford J. Woolf","is_ca":false},{"name":"Kevin Eggan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02100821677264004,"gpt":0.2281163213835972,"spread":0.2071081046109572,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007266125,0.0006485441,0.0002504237,0.0005447413,0.0002149834,0.0004455677,0.0004531367,0.0004356835,0.003416628],"category_scores_gemma":[0.0003476935,0.0003317068,0.0006479693,0.000217224,0.0002692424,0.0002506258,0.0003191156,0.0007201754,0.001194998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002001754,"about_ca_system_score_gemma":0.0002409657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007476403,"about_ca_topic_score_gemma":0.001301404,"domain_scores_codex":[0.9996376,0.00004610264,0.00008660848,0.00007374914,0.00009843553,0.00005744991],"domain_scores_gemma":[0.999797,0.00005216762,0.00002630264,0.00005708265,0.00002584448,0.00004157662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002402482,0.0000479762,0.0002023224,0.000063482,0.00002087137,0.0002316565,0.00006003778,0.0001087148,0.9943083,0.001507223,0.0001126144,0.003096487],"study_design_scores_gemma":[0.00004549697,0.0002415966,0.001629277,0.00001394621,0.00004511601,0.0007460802,0.0000389759,0.0003949066,0.9840319,0.0002845484,0.01252041,0.000007623201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9258337,0.005635889,0.03966752,0.000327826,0.0006117828,0.0006648034,0.007180583,0.0004205012,0.01965747],"genre_scores_gemma":[0.94358,0.003054396,0.01719305,0.0001432153,0.00004564964,0.0003054459,0.007209927,0.0001601295,0.02830829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003416628,"threshold_uncertainty_score":0.01142979,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2065796189","doi":"10.1038/ng1631","title":"Genomic alterations in cultured human embryonic stem cells","year":2005,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":622,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Biology; Embryonic stem cell; Epigenetics; Genetics; Mutant; Mutation; Phenotype; Cell culture; Gene; Stem cell; DNA methylation; Cell biology; Molecular biology; Gene expression","authors":[{"name":"Anirban Maitra","is_ca":false},{"name":"Dan E. Arking","is_ca":false},{"name":"Narayan Shivapurkar","is_ca":false},{"name":"Morna Ikeda","is_ca":false},{"name":"Victor Stastny","is_ca":false},{"name":"Keyaunoosh Kassauei","is_ca":false},{"name":"Guoping Sui","is_ca":false},{"name":"David J. Cutler","is_ca":false},{"name":"Ying Liu","is_ca":false},{"name":"Sandii N. Brimble","is_ca":false},{"name":"Karin Noaksson","is_ca":false},{"name":"Johan Hyllner","is_ca":false},{"name":"Thomas C. Schulz","is_ca":false},{"name":"Xianmin Zeng","is_ca":false},{"name":"William J. Freed","is_ca":false},{"name":"Jeremy M. Crook","is_ca":false},{"name":"Suman Abraham","is_ca":false},{"name":"Alan Colman","is_ca":false},{"name":"Peter Sartipy","is_ca":false},{"name":"Sei‐Ichi Matsui","is_ca":false},{"name":"Melissa Carpenter","is_ca":true},{"name":"Adi F. Gazdar","is_ca":false},{"name":"Mahendra S. Rao","is_ca":false},{"name":"Aravinda Chakravarti","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01064463289577991,"gpt":0.2815304612595475,"spread":0.2708858283637676,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001335845,0.0001582719,0.0001667717,0.0004403802,0.0002172884,0.0003778189,0.0002048926,0.0002391755,0.002274651],"category_scores_gemma":[0.0004456074,0.0002014195,0.0002011311,0.0003316392,0.0001895619,0.0001889729,0.0002112304,0.0004210959,0.0007062592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002867053,"about_ca_system_score_gemma":0.0002046394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002000209,"about_ca_topic_score_gemma":0.002364942,"domain_scores_codex":[0.9997835,0.00004532875,0.00004221721,0.00004392911,0.00006348182,0.00002156929],"domain_scores_gemma":[0.9997247,0.0001090954,0.00003708267,0.00006624256,0.00004104841,0.00002195599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006544833,0.00001385933,0.0008045593,0.00002941908,0.00001093866,0.0002476205,0.00004609,0.0001995116,0.9960656,0.000161762,0.00009515333,0.002260196],"study_design_scores_gemma":[0.00001062641,0.000104014,0.01840659,0.000007343433,0.00003982723,0.0006375226,0.00009469459,0.0005254515,0.975073,0.0001392546,0.004956227,0.000005465239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980838,0.002336839,0.006956953,0.0002740448,0.0001267051,0.00006921818,0.003285251,0.0002136041,0.005899435],"genre_scores_gemma":[0.9897566,0.001107498,0.002358441,0.0001027361,0.00001644836,0.00005630165,0.002954339,0.00007339675,0.003574297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002274651,"threshold_uncertainty_score":0.007609487,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2022959322","doi":"10.1242/dev.043471","title":"FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst","year":2010,"lang":"en","type":"article","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":599,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Vetenskapsrådet","keywords":"Epiblast; Biology; Blastocyst; Inner cell mass; Cell biology; Nanog Homeobox Protein; Embryonic stem cell; Progenitor cell; Cell fate determination; Homeobox protein NANOG; Genetics; Endoderm; Stem cell; Embryogenesis; Transcription factor; Embryo; Gene; Gastrulation; SOX2; Induced pluripotent stem cell","authors":[{"name":"Yojiro Yamanaka","is_ca":true},{"name":"Fredrik Lanner","is_ca":true},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009835357759033285,"gpt":0.2414548609977111,"spread":0.2316195032386778,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001489109,0.0002500218,0.0002180927,0.0002816125,0.0001442102,0.0002966054,0.0002416568,0.0003368468,0.0005993696],"category_scores_gemma":[0.0001717726,0.0003098749,0.0002399883,0.00009585403,0.000155738,0.0002248484,0.0002372036,0.0004471963,0.0005135963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003013892,"about_ca_system_score_gemma":0.0002053036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001212236,"about_ca_topic_score_gemma":0.001668666,"domain_scores_codex":[0.9998621,0.00001966199,0.00001961616,0.00002979898,0.00004273154,0.0000260232],"domain_scores_gemma":[0.9998587,0.00002324354,0.00003928743,0.00002159819,0.00002022969,0.00003686014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005669059,0.000006418365,0.0004390978,0.00002129826,0.000002370562,0.00006723705,0.00002266773,0.00004715722,0.9980578,0.0002309651,0.00001993726,0.001028373],"study_design_scores_gemma":[0.00001817265,0.0001113921,0.01606262,0.00001048318,0.00001104346,0.0002676345,0.00002948452,0.001714758,0.9796872,0.00009398109,0.001987049,0.000006133458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916276,0.001238517,0.004463689,0.00003878642,0.000009485479,0.00004307849,0.0004089494,0.00007618945,0.002093804],"genre_scores_gemma":[0.9901618,0.0006815774,0.003740944,0.00003886791,0.000005910199,0.00006616815,0.0004299768,0.00002919964,0.004845467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001212236,"threshold_uncertainty_score":0.002410352,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1992838550","doi":"10.1182/blood-2003-03-0832","title":"Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":597,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Robarts Research Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Embryoid body; Haematopoiesis; Biology; Embryonic stem cell; Hemangioblast; Cell biology; Stem cell; Progenitor cell; Immunology; Mesoderm; Cellular differentiation; Hematopoietic stem cell; Adult stem cell; Genetics","authors":[{"name":"Kristin Chadwick","is_ca":true},{"name":"Lisheng Wang","is_ca":true},{"name":"Li Li","is_ca":true},{"name":"Pablo Menéndez","is_ca":true},{"name":"Barbara Murdoch","is_ca":true},{"name":"Anne Rouleau","is_ca":true},{"name":"Mickie Bhatia","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01177302468526558,"gpt":0.2436684872283096,"spread":0.231895462543044,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001425184,0.000302357,0.0001113985,0.000236073,0.00007762178,0.0001945266,0.00009425018,0.0001095492,0.0009088966],"category_scores_gemma":[0.0001182637,0.000145154,0.0001442723,0.00009669735,0.0001261308,0.00009642001,0.0002393035,0.000249608,0.0004244857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001284213,"about_ca_system_score_gemma":0.0001590003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002793188,"about_ca_topic_score_gemma":0.0005715932,"domain_scores_codex":[0.999909,0.00002198801,0.000009056312,0.00001113976,0.00003477424,0.00001400007],"domain_scores_gemma":[0.9999473,0.00001510285,0.000009992468,0.000006217645,0.000006444754,0.00001487602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000108865,0.00001546086,0.0003005807,0.00004375854,0.000003892311,0.00004789911,0.0000143713,0.00009533227,0.9959869,0.0001647318,0.00005894973,0.003159303],"study_design_scores_gemma":[0.00001813839,0.00009856385,0.0023754,0.000007766722,0.00001250905,0.0001306631,0.00001258887,0.000396875,0.9918972,0.00006271579,0.004986292,0.000001463184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798205,0.007610558,0.00563198,0.0001505028,0.00004603498,0.00008401398,0.0005742332,0.0001314783,0.005950695],"genre_scores_gemma":[0.9769909,0.005148183,0.008984616,0.00009554242,0.00003643728,0.00006296236,0.0008169247,0.00003825775,0.007826021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009088966,"threshold_uncertainty_score":0.003040612,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2279554517","doi":"10.1038/nrm.2015.27","title":"Pluripotent stem cells in disease modelling and drug discovery","year":2016,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":596,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Rosetrees Trust; New York Stem Cell Foundation","keywords":"Induced pluripotent stem cell; Drug discovery; Embryonic stem cell; Stem cell; Biology; Epigenetics; Disease; Computational biology; Neuroscience; Drug development; Human disease; Human Induced Pluripotent Stem Cells; Drug; Bioinformatics; Medicine; Cell biology; Genetics; Pharmacology; Gene; Pathology","authors":[{"name":"Yishai Avior","is_ca":false},{"name":"Ido Sagi","is_ca":false},{"name":"Nissim Benvenisty","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01983649628657849,"gpt":0.3013654564288228,"spread":0.2815289601422443,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001286013,0.000921766,0.001254262,0.001441967,0.0002345785,0.0009548718,0.001023933,0.001273265,0.00271535],"category_scores_gemma":[0.0007754778,0.000388562,0.0004144805,0.001690497,0.001040464,0.001426952,0.001232099,0.002556519,0.001441027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005138264,"about_ca_system_score_gemma":0.0007415066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004378485,"about_ca_topic_score_gemma":0.0009591316,"domain_scores_codex":[0.9997475,0.00005893353,0.00003115597,0.00003262574,0.0001075042,0.00002238123],"domain_scores_gemma":[0.9996845,0.0001902898,0.00002957503,0.0000169043,0.00005730847,0.00002151758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009678827,0.00004602604,0.0001322248,0.009971164,0.0001037981,0.0003371079,0.00007380079,0.0009641761,0.006611364,0.02821716,0.0280328,0.9254136],"study_design_scores_gemma":[0.00002483052,0.00004568587,0.0001980643,0.001611095,0.00008901484,0.0006196573,0.00003630687,0.0001611496,0.002242946,0.01176073,0.9831928,0.00001771161],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001419017,0.9960369,0.001291729,0.0005724239,0.0004627548,0.000006772965,0.00003115222,0.00001165943,0.001444669],"genre_scores_gemma":[0.001445026,0.9960583,0.0008101615,0.0003581013,0.0003338304,0.00001165214,0.00003842979,0.000002892314,0.000941625],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00271535,"threshold_uncertainty_score":0.009083748,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2082292567","doi":"10.1038/nature06027","title":"IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro","year":2007,"lang":"en","type":"article","venue":"Nature","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":590,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University; McMaster University","funders":"","keywords":"Cell biology; Induced pluripotent stem cell; Fibroblast growth factor; Embryonic stem cell; Stem cell; Biology; Insulin-like growth factor 1 receptor; Cellular differentiation; Growth factor; Receptor; Genetics","authors":[{"name":"Sean C. Bendall","is_ca":true},{"name":"Morag Stewart","is_ca":true},{"name":"Pablo Menéndez","is_ca":true},{"name":"Dustin George","is_ca":true},{"name":"Kausalia Vijayaragavan","is_ca":true},{"name":"Tamra E. Werbowetski‐Ogilvie","is_ca":true},{"name":"Verónica Ramos–Mejía","is_ca":true},{"name":"Anne Rouleau","is_ca":true},{"name":"Jiabi Yang","is_ca":true},{"name":"Marc Bossé","is_ca":true},{"name":"Gilles Lajoie","is_ca":true},{"name":"Mickie Bhatia","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007290529969855367,"gpt":0.2545845136642946,"spread":0.2472939836944392,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004203431,0.0003842972,0.0002733607,0.0004878038,0.0001987612,0.0005179578,0.0003853675,0.0002743492,0.001635724],"category_scores_gemma":[0.0004074325,0.0002317176,0.0002693507,0.0001540701,0.0003248007,0.0003298259,0.000650681,0.000403291,0.000512392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003416393,"about_ca_system_score_gemma":0.0002801559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001176163,"about_ca_topic_score_gemma":0.00245249,"domain_scores_codex":[0.9997584,0.00004593792,0.00001456713,0.00003345011,0.00009113082,0.00005642878],"domain_scores_gemma":[0.9995921,0.000188713,0.00003629083,0.00004972968,0.00005043776,0.00008274824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001412127,0.00001127226,0.0007145832,0.00003685668,0.000006432172,0.0001039911,0.00003997765,0.0001769045,0.9929749,0.001284155,0.0001621705,0.004347569],"study_design_scores_gemma":[0.00002938695,0.00007902895,0.004326772,0.000006825946,0.0000132483,0.0003250905,0.00006161012,0.0008734852,0.9871398,0.0004213774,0.006716772,0.000006630967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9552236,0.005002307,0.02319645,0.0002503574,0.0001481841,0.00005164674,0.00054413,0.0003031967,0.01528016],"genre_scores_gemma":[0.9884949,0.0004907696,0.005652501,0.00008002426,0.00003720043,0.0000292996,0.0002790935,0.00007932422,0.004856843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001635724,"threshold_uncertainty_score":0.005472064,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144578935","doi":"10.1016/j.cell.2011.08.050","title":"Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling","year":2011,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":576,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"Biology; Transcription factor; Transforming growth factor; Transcription (linguistics); Embryonic stem cell; Cell biology; Cell type; Transforming growth factor beta; Genetics; Gene; Cell","authors":[{"name":"Alan C. Mullen","is_ca":false},{"name":"David A. Orlando","is_ca":false},{"name":"Jamie J. Newman","is_ca":false},{"name":"Jakob Lovén","is_ca":false},{"name":"Roshan Kumar","is_ca":false},{"name":"Steve Bilodeau","is_ca":false},{"name":"Jessica Reddy","is_ca":false},{"name":"Matthew G. Guenther","is_ca":false},{"name":"Rodney P. DeKoter","is_ca":true},{"name":"Richard A. Young","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06964327126296888,"gpt":0.2580272797030587,"spread":0.1883840084400898,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003629212,0.0003616792,0.0003584283,0.0004266032,0.0002186284,0.0008058575,0.0002767866,0.0003095354,0.002039976],"category_scores_gemma":[0.0003841758,0.0005024107,0.0003048696,0.0002192323,0.0003442253,0.0007054267,0.0005158507,0.001018479,0.0006484783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005297862,"about_ca_system_score_gemma":0.0002778264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003783406,"about_ca_topic_score_gemma":0.0009297308,"domain_scores_codex":[0.9997082,0.00003400836,0.0000278254,0.00008624813,0.00006040155,0.00008334763],"domain_scores_gemma":[0.9997098,0.00006962034,0.00006932794,0.00003129836,0.00004151986,0.00007846092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009605147,0.000005074164,0.0005889916,0.00001489317,0.000002950743,0.00002327143,0.00003508557,0.00002701276,0.9976894,0.0004915011,0.00003496265,0.000990827],"study_design_scores_gemma":[0.00002101836,0.0000814542,0.02794893,0.00001713591,0.0000279982,0.0002033414,0.0001788381,0.001109141,0.9667284,0.0005231344,0.003150058,0.00001049595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838831,0.003473411,0.006535342,0.0002142523,0.0000919032,0.00003724865,0.0009045324,0.0001035513,0.004756515],"genre_scores_gemma":[0.9912883,0.001295199,0.00185973,0.0001090712,0.00004013455,0.00003481488,0.000780112,0.00008032045,0.00451223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002039976,"threshold_uncertainty_score":0.006824374,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2167226908","doi":"10.1038/sj.embor.7400279","title":"Oct4 is required for primordial germ cell survival","year":2004,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":565,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Embryonic stem cell; Germline; Cell biology; Stem cell; Inner cell mass; Germ cell; Genetics; Embryo; Lineage (genetic); Cellular differentiation; Null cell; Function (biology); Gene; Embryogenesis; Blastocyst","authors":[{"name":"James Kehler","is_ca":false},{"name":"Elena Tolkunova","is_ca":false},{"name":"Birgit Koschorz","is_ca":false},{"name":"Maurizio Pesce","is_ca":false},{"name":"Luca Gentile","is_ca":false},{"name":"Michele Boiani","is_ca":false},{"name":"Hilda Lomelı́","is_ca":true},{"name":"András Nagy","is_ca":true},{"name":"K. John McLaughlin","is_ca":false},{"name":"Hans R. Schöler","is_ca":false},{"name":"А. Н. Томилин","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01884365741436072,"gpt":0.2866117462480047,"spread":0.2677680888336439,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001862439,0.0004062335,0.0002962298,0.0004039682,0.0004348651,0.0009358975,0.0004061805,0.0004676014,0.00262646],"category_scores_gemma":[0.0002962069,0.000512896,0.0003371869,0.0001960529,0.0004143967,0.0004994674,0.0004809306,0.001014743,0.001109471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00080064,"about_ca_system_score_gemma":0.0006240357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002367335,"about_ca_topic_score_gemma":0.004605286,"domain_scores_codex":[0.9997764,0.00002328169,0.00001986908,0.00003596628,0.00006976621,0.00007471749],"domain_scores_gemma":[0.9995555,0.00006267526,0.0001127611,0.00005541092,0.00005687663,0.0001568249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001618719,0.000007986708,0.000486021,0.00002299916,0.000008152126,0.0001171719,0.000005278932,0.0000723648,0.9979042,0.0002040574,0.0000822717,0.0009274592],"study_design_scores_gemma":[0.00002668729,0.00004239585,0.01374004,0.000005891918,0.00002595559,0.000585938,0.00004412517,0.001127486,0.9800099,0.000230414,0.00415187,0.000009513587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842636,0.00250098,0.005626325,0.0004776154,0.0001244437,0.00001950795,0.001077611,0.0003682639,0.00554158],"genre_scores_gemma":[0.9864987,0.0006991324,0.002221429,0.0001605917,0.00002149868,0.00001257579,0.001676803,0.0001825868,0.008526746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00262646,"threshold_uncertainty_score":0.008786321,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2034862301","doi":"10.1038/nbt.2005","title":"SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells","year":2011,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":562,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Embryonic stem cell; Biology; Cell biology; Cell sorting; Stem cell; Population; Cell; Myocyte; Molecular biology; Genetics; Gene; Medicine","authors":[{"name":"Nicole Dubois","is_ca":true},{"name":"April M. Craft","is_ca":true},{"name":"Parveen Sharma","is_ca":true},{"name":"David A. Elliott","is_ca":false},{"name":"Edouard G. Stanley","is_ca":false},{"name":"Andrew G. Elefanty","is_ca":false},{"name":"Anthony O. Gramolini","is_ca":true},{"name":"Gordon Keller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01917272654380797,"gpt":0.2467523835300174,"spread":0.2275796569862094,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003220264,0.0006630101,0.0005169415,0.000784257,0.0003214013,0.0004370654,0.0005807531,0.0004413922,0.001849128],"category_scores_gemma":[0.0002555609,0.0004485054,0.0004183358,0.000581579,0.0003586188,0.0003784387,0.0004970746,0.001231433,0.00224157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000173043,"about_ca_system_score_gemma":0.0002411695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002038685,"about_ca_topic_score_gemma":0.0005378439,"domain_scores_codex":[0.9996294,0.00006589425,0.00004213059,0.00007239939,0.000149874,0.00004022469],"domain_scores_gemma":[0.9997076,0.00009052023,0.00007965985,0.00003508052,0.00003298006,0.0000541555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003830444,0.000007455976,0.00006478695,0.0000357257,0.000004754504,0.00004472442,0.00001010559,0.00001820845,0.9975816,0.0001304356,0.0001028292,0.001961098],"study_design_scores_gemma":[0.0000110445,0.00007745481,0.0009456156,0.000006684734,0.00002369711,0.0005485518,0.000008079794,0.0004192454,0.9886086,0.00006218252,0.009283565,0.000005281312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.58941,0.01208218,0.3694526,0.0007387818,0.0003156535,0.0003858761,0.004580101,0.00327233,0.01976243],"genre_scores_gemma":[0.7702019,0.01163136,0.173761,0.0003975227,0.0002345134,0.0004261479,0.01439551,0.0009953174,0.0279568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001849128,"threshold_uncertainty_score":0.006185889,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2076194888","doi":"10.1038/nbt.1580","title":"Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells","year":2009,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":490,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Reprogramming; Homeobox protein NANOG; Induced pluripotent stem cell; Biology; Embryonic stem cell; Cell biology; Stem cell; SOX2; Cellular differentiation; Rex1; Cell potency; Population; Somatic cell; Genetics; Cell; Gene","authors":[{"name":"Elayne M. Chan","is_ca":false},{"name":"Sutheera Ratanasirintrawoot","is_ca":false},{"name":"In‐Hyun Park","is_ca":false},{"name":"Philip D. Manos","is_ca":false},{"name":"Yuin‐Han Loh","is_ca":false},{"name":"Hongguang Huo","is_ca":false},{"name":"Justine D. Miller","is_ca":false},{"name":"Odelya Hartung","is_ca":false},{"name":"J. Rho","is_ca":false},{"name":"Tan A. Ince","is_ca":false},{"name":"George Q. Daley","is_ca":false},{"name":"Thorsten M. Schlaeger","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005676962884641728,"gpt":0.2567320944178668,"spread":0.2510551315332251,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003275656,0.0003549642,0.000389207,0.000411338,0.0002553159,0.0007718561,0.0004480037,0.0007994114,0.002258757],"category_scores_gemma":[0.0002602678,0.0004191452,0.00036483,0.0002705062,0.0003258742,0.0005641411,0.0004530369,0.001013207,0.00150163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002374505,"about_ca_system_score_gemma":0.0002256361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005432115,"about_ca_topic_score_gemma":0.0008341856,"domain_scores_codex":[0.9998149,0.00001805243,0.00001986041,0.00005299802,0.0000483281,0.00004582177],"domain_scores_gemma":[0.9997495,0.00009276004,0.00002761145,0.00005494372,0.00003496108,0.00004018703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005137357,0.000009117723,0.0002072182,0.00001453617,0.000004083488,0.0000797264,0.00003092671,0.00004689301,0.9973704,0.0003215288,0.00005990133,0.001804344],"study_design_scores_gemma":[0.00001051422,0.00004799774,0.004658282,0.000007154817,0.00001698732,0.0007131241,0.00004251179,0.001336184,0.9898252,0.0001616188,0.003175331,0.000005128759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.948382,0.001422468,0.04004968,0.0003912963,0.00008179305,0.00006715574,0.001092436,0.0004679675,0.008045397],"genre_scores_gemma":[0.944533,0.001421549,0.03828513,0.0002499773,0.00004905558,0.000134463,0.003868247,0.0006101163,0.01084855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002258757,"threshold_uncertainty_score":0.00755626,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1985439298","doi":"10.1073/pnas.1319738111","title":"Derivation of naïve human embryonic stem cells","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":470,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Embryonic stem cell; Endoderm; Cell culture; Cell biology; Induced pluripotent stem cell; Stem cell; Embryo; Biology; Molecular biology; Chemistry; Genetics; Gene","authors":[{"name":"Carol B. Ware","is_ca":false},{"name":"Angelique M. Nelson","is_ca":false},{"name":"Brigham H. Mecham","is_ca":false},{"name":"Jennifer Hesson","is_ca":false},{"name":"Wenyu Zhou","is_ca":false},{"name":"Erica C. Jonlin","is_ca":false},{"name":"Antonio J. Jiménez‐Caliani","is_ca":true},{"name":"Xinxian Deng","is_ca":false},{"name":"Christopher Cavanaugh","is_ca":false},{"name":"Savannah Cook","is_ca":false},{"name":"Paul J. Tesar","is_ca":false},{"name":"Jeffrey Okada","is_ca":false},{"name":"Lilyana Margaretha","is_ca":false},{"name":"Henrik Sperber","is_ca":false},{"name":"Michael Choi","is_ca":false},{"name":"C. Anthony Blau","is_ca":false},{"name":"Piper M. Treuting","is_ca":false},{"name":"R. David Hawkins","is_ca":false},{"name":"Vincenzo Cirulli","is_ca":true},{"name":"Hannele Ruohola‐Baker","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0353449108484306,"gpt":0.3086507249786091,"spread":0.2733058141301785,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004583417,0.0003415421,0.0003460393,0.0002427056,0.0003258493,0.0005860553,0.0005352295,0.0003063911,0.01055046],"category_scores_gemma":[0.0003850728,0.0003554928,0.0002494922,0.0002184003,0.000190639,0.0002752258,0.0004400765,0.0007662197,0.007201768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001570914,"about_ca_system_score_gemma":0.0005381092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004525451,"about_ca_topic_score_gemma":0.0008842554,"domain_scores_codex":[0.9996146,0.00003505117,0.00008303811,0.00008372171,0.0001495064,0.00003402862],"domain_scores_gemma":[0.9997961,0.00002237127,0.00001379361,0.00006497134,0.00006844231,0.00003429549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002443042,0.0001041681,0.0009176867,0.0001808498,0.00001119009,0.000420749,0.0001939908,0.0002289353,0.9654797,0.003687659,0.00282299,0.02570774],"study_design_scores_gemma":[0.0001147239,0.0007258344,0.003727339,0.0001047303,0.00004174718,0.002265743,0.0001534431,0.00215353,0.7800533,0.001405996,0.209213,0.00004062833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.562255,0.006611853,0.2701903,0.001089091,0.001872467,0.008530175,0.03934506,0.00276291,0.1073432],"genre_scores_gemma":[0.6023745,0.008655681,0.2230776,0.001279924,0.0002820883,0.003188167,0.04405118,0.0006210962,0.1164698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01055046,"threshold_uncertainty_score":0.03529483,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011687861","doi":"10.1038/nbt.2915","title":"Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells","year":2014,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":468,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network","funders":"National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Institutes of Health; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Wnt signaling pathway; Biology; Induced pluripotent stem cell; Haematopoiesis; Cell biology; Stem cell; Progenitor cell; Embryonic stem cell; CD34; Population; Signal transduction; Genetics; Gene; Medicine","authors":[{"name":"Christopher M. Sturgeon","is_ca":true},{"name":"Andrea Ditadi","is_ca":true},{"name":"Génève Awong","is_ca":true},{"name":"Marion Kennedy","is_ca":true},{"name":"Gordon Keller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009699612335414144,"gpt":0.2400502116427157,"spread":0.2303505993073016,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002019331,0.0002715761,0.0001981846,0.0003407042,0.0002102699,0.0009059734,0.0002081032,0.0002768705,0.001023712],"category_scores_gemma":[0.0003819169,0.0003618032,0.0001956129,0.0002383357,0.0002701143,0.0003687511,0.0003860607,0.0005395696,0.000532194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000495053,"about_ca_system_score_gemma":0.0003794126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009425689,"about_ca_topic_score_gemma":0.002443981,"domain_scores_codex":[0.9997707,0.00002732512,0.00002470286,0.00003470639,0.00008562638,0.00005698863],"domain_scores_gemma":[0.9998205,0.00004228051,0.00004611812,0.00002211556,0.00002356842,0.00004534691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000230287,0.000008956402,0.0009935689,0.00002988191,0.000004610316,0.00008379765,0.00003343929,0.0001714893,0.9926045,0.001363246,0.0001665859,0.00430965],"study_design_scores_gemma":[0.00002653471,0.00006148958,0.01149711,0.000009100369,0.00001392269,0.0002207287,0.00004765016,0.00141869,0.9817486,0.0004538773,0.004494217,0.000007969043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816949,0.003598082,0.007411535,0.0003168336,0.00004702763,0.00003137792,0.001112954,0.0002441261,0.005543159],"genre_scores_gemma":[0.988245,0.001528285,0.002590345,0.00006614179,0.00001504258,0.00001684797,0.001198671,0.00007099396,0.006268537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001023712,"threshold_uncertainty_score":0.003591835,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2141926462","doi":"10.1126/science.288.5466.665","title":"Extension of Cell Life-Span and Telomere Length in Animals Cloned from Senescent Somatic Cells","year":2000,"lang":"en","type":"article","venue":"Science","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":468,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; Terry Fox Research Institute","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute on Aging","keywords":"Telomere; Somatic cell; Biology; Cloning (programming); Population; Senescence; Genetics; Life span; Southern blot; Gene; Molecular biology; Andrology; Cell biology; Evolutionary biology; Medicine","authors":[{"name":"Robert Lanza","is_ca":false},{"name":"José B. Cibelli","is_ca":false},{"name":"Catherine Blackwell","is_ca":false},{"name":"Vincent J. Cristofalo","is_ca":false},{"name":"Mary Kay Francis","is_ca":false},{"name":"Gabriela M. Baerlocher","is_ca":true},{"name":"Jennifer Sze Man Mak","is_ca":true},{"name":"Michael Schertzer","is_ca":true},{"name":"Elizabeth A. Chavez","is_ca":true},{"name":"Nancy Sawyer","is_ca":false},{"name":"Peter M. Lansdorp","is_ca":true},{"name":"Michael D. West","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009900820868093232,"gpt":0.2466345255614412,"spread":0.236733704693348,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004023205,0.0001628216,0.0001507257,0.000321477,0.0001821115,0.0002681081,0.000198834,0.000257551,0.0006943108],"category_scores_gemma":[0.000559867,0.00009903707,0.0001514865,0.0001124044,0.0002908003,0.0002034039,0.0002988082,0.0004556889,0.0001929322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001940514,"about_ca_system_score_gemma":0.0001716414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004911207,"about_ca_topic_score_gemma":0.0006303726,"domain_scores_codex":[0.9998066,0.00003302922,0.00002228135,0.00003949455,0.00005689167,0.0000417409],"domain_scores_gemma":[0.9993961,0.0001716967,0.0001556771,0.00007081184,0.00008625344,0.0001193843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005807425,0.00001690737,0.003046301,0.0000146103,0.000006081838,0.0001387705,0.00008885483,0.00002737043,0.9943587,0.00009136571,0.000009161162,0.002143809],"study_design_scores_gemma":[0.0000258453,0.001563285,0.07282066,0.00002297781,0.00009648039,0.003459113,0.0002095557,0.0007629779,0.9164022,0.0002230926,0.004396216,0.00001764488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964105,0.0004934201,0.002715925,0.00002308434,0.000007445497,0.00001032732,0.0000670325,0.00001500852,0.0002571535],"genre_scores_gemma":[0.9949269,0.0005585703,0.002408244,0.00002181722,0.000006420566,0.00002037776,0.0005296846,0.00001204685,0.001515873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006943108,"threshold_uncertainty_score":0.002322674,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044193480","doi":"10.1634/stemcells.2008-0183","title":"Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories","year":2008,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":463,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Heart and Stroke Foundation; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Biology; Endoderm; Embryonic stem cell; Cell biology; Cellular differentiation; Embryoid body; Mesoderm; Induced pluripotent stem cell; Directed differentiation; Cell type; Cell; Genetics; Gene","authors":[{"name":"Céline L. Bauwens","is_ca":true},{"name":"Raheem Peerani","is_ca":true},{"name":"Sylvia Niebruegge","is_ca":true},{"name":"Kimberly A. Woodhouse","is_ca":true},{"name":"Eugenia Kumacheva","is_ca":true},{"name":"Mansoor Husain","is_ca":true},{"name":"Peter W. Zandstra","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0143533179970233,"gpt":0.2461354132746366,"spread":0.2317820952776133,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002843978,0.0002573951,0.0001787883,0.0001632267,0.0001044813,0.000411114,0.000135169,0.0001513408,0.0004775627],"category_scores_gemma":[0.0004436291,0.000174195,0.000134765,0.0001446502,0.0001089741,0.0001423049,0.0002748084,0.0002351623,0.0001960288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002686767,"about_ca_system_score_gemma":0.0001470511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005900425,"about_ca_topic_score_gemma":0.0009330039,"domain_scores_codex":[0.9997752,0.00004202814,0.00003100205,0.0000600488,0.00006792206,0.00002377155],"domain_scores_gemma":[0.9996451,0.0001561921,0.00007402591,0.00003863366,0.00005291272,0.00003316288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003923683,0.00001019843,0.0008920984,0.00001774019,0.000004953502,0.00002114741,0.00003155827,0.000505591,0.9965816,0.00004013407,0.00002482912,0.00183084],"study_design_scores_gemma":[0.000005011573,0.00009548823,0.01339902,0.000003396375,0.00001622571,0.00005727952,0.00002435178,0.003478671,0.9820465,0.00003046346,0.0008372045,0.000006323264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915011,0.0005799687,0.00642758,0.0000274179,0.000006986403,0.00002357569,0.000286305,0.00006838508,0.001078691],"genre_scores_gemma":[0.9950061,0.0003679944,0.00352639,0.00002297729,0.000004494414,0.00004910796,0.0003679502,0.00003693539,0.0006180156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005900425,"threshold_uncertainty_score":0.00194943,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2091790925","doi":"10.1038/nbt1102","title":"Characterization and culture of human embryonic stem cells","year":2005,"lang":"en","type":"review","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":458,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Embryonic stem cell; Cell culture; Cell biology; Induced pluripotent stem cell; Stem cell; Biology; KOSR; In vitro; Karyotype; Cellular differentiation; Genetics; Chromosome; Gene","authors":[{"name":"Lisa Hoffman","is_ca":true},{"name":"Melissa K. Carpenter","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01462281025421574,"gpt":0.3094408560201286,"spread":0.2948180457659128,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001668333,0.001232558,0.001319471,0.001908008,0.0002526115,0.001169526,0.001634628,0.001197963,0.001271561],"category_scores_gemma":[0.001296438,0.0004834973,0.0004449278,0.00191113,0.001019285,0.001587053,0.0006626137,0.002114939,0.002677944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009707041,"about_ca_system_score_gemma":0.001069586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001074603,"about_ca_topic_score_gemma":0.001511843,"domain_scores_codex":[0.9994034,0.00007169232,0.00008973864,0.00009940686,0.000296696,0.00003915152],"domain_scores_gemma":[0.9990612,0.0004009215,0.00009762444,0.00008694623,0.0003049564,0.00004826257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008196438,0.00007399034,0.0004551664,0.006099068,0.00003638507,0.0004514062,0.00009233009,0.0008519359,0.07835912,0.01155013,0.01458396,0.8873645],"study_design_scores_gemma":[0.00001866538,0.00008167684,0.001468024,0.0007696314,0.00007245642,0.001873233,0.00007835528,0.0003357141,0.0941084,0.005030125,0.8961265,0.00003735803],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00232709,0.9531841,0.03210909,0.001254204,0.001336378,0.00009511118,0.0003781124,0.0001251198,0.009190775],"genre_scores_gemma":[0.007111265,0.9602489,0.02119934,0.0009385594,0.0004283248,0.0001017527,0.001079657,0.00004477494,0.008847386],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001908008,"threshold_uncertainty_score":0.008823097,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044217732","doi":"10.1016/j.cell.2012.03.049","title":"Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells","year":2012,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":455,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Dopamine; Identification (biology); Dopamine receptor; Stem cell; Cancer stem cell; Cancer; Cancer cell; Dopamine receptor D2; Computational biology; Pharmacology; Cell biology; Neuroscience; Genetics; Ecology","authors":[{"name":"Eleftherios Sachlos","is_ca":true},{"name":"Ruth M. Risueño","is_ca":true},{"name":"Sarah Laronde","is_ca":true},{"name":"Zoya Shapovalova","is_ca":true},{"name":"Jong‐Hee Lee","is_ca":true},{"name":"Jennifer Russell","is_ca":true},{"name":"Monika Malig","is_ca":true},{"name":"Jamie McNicol","is_ca":true},{"name":"Aline Fiebig‐Comyn","is_ca":true},{"name":"Monica Graham","is_ca":true},{"name":"Marilyne Levadoux‐Martin","is_ca":true},{"name":"Jung Bok Lee","is_ca":true},{"name":"Andrew O. Giacomelli","is_ca":true},{"name":"John A. Hassell","is_ca":true},{"name":"Daniela Fischer-Russell","is_ca":true},{"name":"Michael Trus","is_ca":true},{"name":"Ronan Foley","is_ca":true},{"name":"Brian Leber","is_ca":true},{"name":"Anargyros Xenocostas","is_ca":true},{"name":"Eric D. Brown","is_ca":true},{"name":"Tony Collins","is_ca":true},{"name":"Mickie Bhatia","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02267657549456842,"gpt":0.2840677637150012,"spread":0.2613911882204328,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002141616,0.000547922,0.0006413012,0.0005270221,0.0002145741,0.0004941466,0.0003451637,0.0004818527,0.001509552],"category_scores_gemma":[0.0001812219,0.0001883747,0.0003556159,0.0002500318,0.0001976468,0.000268883,0.0002077692,0.0007435682,0.0004876751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005269997,"about_ca_system_score_gemma":0.0006275367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008080747,"about_ca_topic_score_gemma":0.002511227,"domain_scores_codex":[0.9998943,0.00001968488,0.00001159707,0.00001959299,0.00002966118,0.00002517919],"domain_scores_gemma":[0.9998941,0.00001828135,0.00003045343,0.000007264389,0.00002327519,0.00002664354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004102418,0.0002508149,0.001013816,0.0001464337,0.00005172719,0.0002646293,0.00002155977,0.0003990678,0.9630315,0.001422537,0.0006735068,0.03231426],"study_design_scores_gemma":[0.0003357342,0.003099326,0.003477755,0.00002948551,0.0002083868,0.001789866,0.00003826812,0.001731254,0.9619663,0.0002956206,0.02700186,0.00002619102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9355916,0.0229979,0.02098761,0.001669888,0.0003304223,0.0008448504,0.001418556,0.0003603016,0.01579881],"genre_scores_gemma":[0.9610828,0.01138921,0.01780387,0.0006376334,0.0000807819,0.0003530867,0.001496083,0.00003657169,0.007119976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001509552,"threshold_uncertainty_score":0.005049944,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2051433490","doi":"10.1084/jem.192.9.1365","title":"The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells","year":2000,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":429,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Medical Research Council; Medical Research Council Canada; Amgen","keywords":"Stem cell; Cell biology; Biology; Stem cell factor; Haematopoiesis; Notch signaling pathway; Induced pluripotent stem cell; Embryonic stem cell; Progenitor cell; Adult stem cell; Cellular differentiation; Immunology; Signal transduction; Genetics","authors":[{"name":"Frances N. Karanu","is_ca":true},{"name":"Barbara Murdoch","is_ca":true},{"name":"Lisa Gallacher","is_ca":true},{"name":"Dongmei Wu","is_ca":true},{"name":"Masahide Koremoto","is_ca":false},{"name":"Seiji Sakano","is_ca":false},{"name":"Mickie Bhatia","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02476536814459541,"gpt":0.3120244641585216,"spread":0.2872590960139262,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008669676,0.000299953,0.0001590887,0.0002606323,0.0001564065,0.0003305562,0.0001487958,0.0002150726,0.0006227354],"category_scores_gemma":[0.00007842697,0.0001075147,0.0001223091,0.0001526965,0.0002801867,0.0001834607,0.0002608287,0.0003299702,0.0003740125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003037372,"about_ca_system_score_gemma":0.0002200906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003998133,"about_ca_topic_score_gemma":0.0006380739,"domain_scores_codex":[0.9999471,0.000007988707,0.000005170337,0.0000125457,0.00001802434,0.000009285729],"domain_scores_gemma":[0.9999667,0.000005722613,0.000007334588,0.000003475866,0.000003406966,0.00001324146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007631692,0.00001008401,0.000757275,0.00006177316,0.000002799251,0.0001305796,0.00002232512,0.0001418442,0.9882279,0.0006629325,0.000132113,0.009774082],"study_design_scores_gemma":[0.00001346357,0.0002694982,0.005510723,0.00001245105,0.00001407689,0.001185864,0.00003349284,0.0006027022,0.9725958,0.0003396789,0.01941469,0.000007600396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9656849,0.01781763,0.011028,0.000574172,0.00009300158,0.00006237165,0.001148787,0.0001812478,0.003409956],"genre_scores_gemma":[0.9765379,0.006613498,0.009262167,0.0001460528,0.00005328279,0.00003321457,0.001857648,0.0000158687,0.005480331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006227354,"threshold_uncertainty_score":0.002203703,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2073523882","doi":"10.1002/jnr.22054","title":"Stem cell‐based cell therapy in neurological diseases: A review","year":2009,"lang":"en","type":"review","venue":"Journal of Neuroscience Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":422,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Cell therapy; Stem-cell therapy; Cell; Medicine; Stem cell; Neuroscience; Psychology; Biology; Cell biology","authors":[{"name":"Seung Up Kim","is_ca":true},{"name":"Jean de Vellis","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1575230197218003,"gpt":0.4391792422433931,"spread":0.2816562225215928,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007745702,0.001189395,0.001674614,0.00259765,0.0003157152,0.0012916,0.001112816,0.001458358,0.002299871],"category_scores_gemma":[0.0005202219,0.0002999456,0.0006167402,0.003215888,0.0006259561,0.001742075,0.0007248379,0.001644389,0.001859371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004425276,"about_ca_system_score_gemma":0.001028015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008426376,"about_ca_topic_score_gemma":0.001099612,"domain_scores_codex":[0.9997664,0.00004183071,0.00004619449,0.00004215883,0.0000829067,0.00002045408],"domain_scores_gemma":[0.9996803,0.0001839638,0.00004085086,0.000009334688,0.00005616849,0.00002939264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009365282,0.0001782546,0.0001960792,0.02559052,0.000121912,0.0003074679,0.0001540481,0.0007823461,0.005096885,0.003726933,0.0259607,0.9377913],"study_design_scores_gemma":[0.00002678805,0.0002965567,0.0009624063,0.005721924,0.0001994773,0.001618089,0.00010294,0.0001985555,0.001370595,0.002040094,0.987428,0.00003449643],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001626949,0.9986259,0.0002162694,0.0001271144,0.0002097335,0.000007996082,0.00001407178,0.000008144178,0.0006281065],"genre_scores_gemma":[0.0004778842,0.9986138,0.0003142069,0.000145599,0.0001481397,0.00001107734,0.00002312987,0.000001864978,0.0002641715],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00259765,"threshold_uncertainty_score":0.007693827,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044025778","doi":"10.1038/nrm2466","title":"The promise of human induced pluripotent stem cells for research and therapy","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":419,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"","keywords":"Induced pluripotent stem cell; Reprogramming; Embryonic stem cell; Regenerative medicine; Somatic cell; Human Induced Pluripotent Stem Cells; Stem cell; Biology; Cell therapy; Cell potency; Cell biology; Cell; Genetics","authors":[{"name":"Shin‐Ichi Nishikawa","is_ca":false},{"name":"Robert A. Goldstein","is_ca":true},{"name":"Concepcion R. Nierras","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.109004600548994,"gpt":0.4171959208418612,"spread":0.3081913202928672,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002228435,0.001197008,0.001757476,0.001287632,0.0004088253,0.001403558,0.001512935,0.002876043,0.005058998],"category_scores_gemma":[0.001185289,0.0002988318,0.0005115896,0.001421312,0.001487209,0.003195466,0.001163385,0.00447949,0.00270492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001079617,"about_ca_system_score_gemma":0.001206088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007263553,"about_ca_topic_score_gemma":0.001463648,"domain_scores_codex":[0.9996433,0.00008163356,0.00003316895,0.00004428927,0.000166586,0.00003097341],"domain_scores_gemma":[0.9992253,0.0004623914,0.00003678875,0.00003163997,0.0001642588,0.00007969039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001345616,0.00006500091,0.000131707,0.005268811,0.00007523021,0.000374864,0.00008096904,0.0006517497,0.006753011,0.03050455,0.1044019,0.8515576],"study_design_scores_gemma":[0.00003103489,0.00004310897,0.0001521097,0.0005561984,0.00003359367,0.0004385129,0.00003944306,0.00008592165,0.0007577699,0.009503067,0.9883471,0.00001215423],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001422281,0.9907323,0.001409346,0.003186997,0.002103029,0.000008846321,0.00003955092,0.00002758078,0.002350186],"genre_scores_gemma":[0.0008927863,0.9934106,0.001043872,0.0018279,0.001015499,0.00001341203,0.0000530884,0.00000479614,0.001737949],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005058998,"threshold_uncertainty_score":0.01692408,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1990180850","doi":"10.1242/dev.050146","title":"The role of FGF/Erk signaling in pluripotent cells","year":2010,"lang":"en","type":"article","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":414,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Vetenskapsrådet","keywords":"Epiblast; Biology; Cell biology; Fibroblast growth factor; Induced pluripotent stem cell; Embryonic stem cell; Stem cell; Germ layer; Endoderm; Genetics; Embryo; Gastrulation; Embryogenesis","authors":[{"name":"Fredrik Lanner","is_ca":true},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005542335622454821,"gpt":0.2254207543074829,"spread":0.2198784186850281,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001916768,0.0002532442,0.0001046681,0.0001774161,0.0002445984,0.0003425113,0.0001657899,0.0002791521,0.0007324604],"category_scores_gemma":[0.0001563576,0.0000934625,0.0001200175,0.0001058132,0.0003168502,0.0003770172,0.0003126418,0.0004284822,0.0002292819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002195999,"about_ca_system_score_gemma":0.0002007008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002377812,"about_ca_topic_score_gemma":0.0002993754,"domain_scores_codex":[0.9999186,0.00001532714,0.000007578097,0.00001376278,0.0000290792,0.00001562142],"domain_scores_gemma":[0.9999608,0.000007962013,0.000007274371,0.00000428933,0.00001045876,0.000009231763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000203533,0.00001938056,0.0009611521,0.0003855934,0.00001228047,0.0007175604,0.00007880389,0.0005634426,0.932695,0.0169821,0.0004347321,0.04694649],"study_design_scores_gemma":[0.00002362748,0.0001746873,0.008822489,0.00005163108,0.00003757505,0.002880197,0.0001020883,0.00200819,0.9365549,0.008932332,0.04038736,0.00002480882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8027668,0.1053792,0.05417708,0.003936295,0.0004364335,0.00005898724,0.0009719087,0.0003504746,0.03192277],"genre_scores_gemma":[0.962553,0.02402877,0.006867208,0.0002464288,0.0001237178,0.00002019041,0.0003284205,0.00001801707,0.005814286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007324604,"threshold_uncertainty_score":0.002450287,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2077517942","doi":"10.1074/jbc.m406467200","title":"Regulation of Embryonic Stem Cell Self-renewal by Phosphoinositide 3-Kinase-dependent Signaling","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":414,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Circulatory and Respiratory Health; Medical Research Council; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Wellcome Trust","keywords":"Embryonic stem cell; Cell biology; Phosphoinositide 3-kinase; Stem cell; Signal transduction; Biology; Kinase; PI3K/AKT/mTOR pathway; Genetics; Gene","authors":[{"name":"Nick Paling","is_ca":false},{"name":"Helen Wheadon","is_ca":false},{"name":"Heather K. Bone","is_ca":false},{"name":"Melanie J. Welham","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0119535746790586,"gpt":0.2370599908178349,"spread":0.2251064161387762,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009269448,0.0003047271,0.0001746854,0.0001804671,0.00009289756,0.0002954184,0.0001605189,0.0001532992,0.0006630342],"category_scores_gemma":[0.0000712262,0.00008105524,0.0001840389,0.0001255324,0.0001863805,0.0001570129,0.0001969441,0.0004810982,0.0002775555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002774045,"about_ca_system_score_gemma":0.0001539768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002891843,"about_ca_topic_score_gemma":0.0004959605,"domain_scores_codex":[0.9998884,0.00001460962,0.00001556655,0.00001965178,0.00004283998,0.00001884164],"domain_scores_gemma":[0.9999417,0.00001067143,0.00001882134,0.000008550192,0.000007316576,0.00001302148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004304998,0.00001688471,0.00015567,0.0000280126,0.000003187844,0.00002430497,0.000009411579,0.00004221969,0.9974384,0.0001029028,0.00002781518,0.002108123],"study_design_scores_gemma":[0.000005352632,0.00007444925,0.00400095,0.000003932724,0.000007180827,0.00006708696,0.000009545884,0.0006589202,0.9933903,0.00004297318,0.001737253,0.000002129894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861555,0.0052309,0.004728097,0.0001296981,0.00003646183,0.00003923785,0.0006563258,0.0001759976,0.002847905],"genre_scores_gemma":[0.9927531,0.002201707,0.002418335,0.00005837318,0.00001126813,0.00004467524,0.0006021696,0.0000177269,0.001892636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006630342,"threshold_uncertainty_score":0.002218068,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1965674737","doi":"10.1371/journal.pone.0001565","title":"Reproducible, Ultra High-Throughput Formation of Multicellular Organization from Single Cell Suspension-Derived Human Embryonic Stem Cell Aggregates","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":409,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Stem Cell Network","keywords":"Embryonic stem cell; Embryoid body; Germ layer; Cell biology; Regenerative medicine; Multicellular organism; Epiblast; Morphogenesis; Biology; Stem cell; Nanotechnology; Embryogenesis; Cell; Materials science; Embryo; Induced pluripotent stem cell; Genetics","authors":[{"name":"Mark Ungrin","is_ca":true},{"name":"Chirag Joshi","is_ca":true},{"name":"Andra Nica","is_ca":true},{"name":"Céline L. Bauwens","is_ca":true},{"name":"Peter W. Zandstra","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03536008210969776,"gpt":0.2163318959746378,"spread":0.18097181386494,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005773847,0.0003525888,0.0002961807,0.0003878264,0.0002274522,0.0005210551,0.0003350638,0.0003156529,0.0005619397],"category_scores_gemma":[0.0004085882,0.0002184915,0.0003139455,0.0002368436,0.0002204834,0.0002693235,0.0004837677,0.0004816589,0.0004984748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002802962,"about_ca_system_score_gemma":0.000198291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002445935,"about_ca_topic_score_gemma":0.000684174,"domain_scores_codex":[0.9996921,0.00004172482,0.00004292541,0.00007552852,0.0001212445,0.00002660774],"domain_scores_gemma":[0.9996709,0.0001115039,0.00005459198,0.00006661211,0.00006819125,0.00002831708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001505464,0.00001507275,0.0001889302,0.00002545032,0.000005783304,0.00002718436,0.00002581854,0.0003726913,0.9962193,0.00006559849,0.00009849133,0.00294053],"study_design_scores_gemma":[0.000005436331,0.0000701601,0.001198686,0.000003329596,0.000009866406,0.00006970419,0.00001094047,0.002818701,0.9945826,0.00004068001,0.001186404,0.00000347284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7110062,0.002176562,0.2782859,0.0002220069,0.00009122528,0.0006295225,0.001817127,0.001828264,0.003943233],"genre_scores_gemma":[0.8489922,0.001288962,0.1447757,0.00007541189,0.00002732103,0.0004090191,0.001798191,0.0001446236,0.002488503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005773847,"threshold_uncertainty_score":0.003053546,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2142303444","doi":"10.1242/dev.01715","title":"Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts","year":2005,"lang":"en","type":"article","venue":"Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":406,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Epiblast; Endoderm; Biology; Embryonic stem cell; Blastocyst; Inner cell mass; Cell biology; Trophoblast; Chimera (genetics); Embryo; Genetics; Embryogenesis; Placenta; Gastrulation; Gene; Fetus","authors":[{"name":"Tilo Kunath","is_ca":true},{"name":"Danielle Arnaud","is_ca":false},{"name":"Gary D. Uy","is_ca":false},{"name":"Ikuhiro Okamoto","is_ca":false},{"name":"Corinne Chureau","is_ca":false},{"name":"Yojiro Yamanaka","is_ca":true},{"name":"Édith Heard","is_ca":false},{"name":"Richard L. Gardner","is_ca":false},{"name":"Philip Avner","is_ca":false},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01299644876376796,"gpt":0.2474815055296741,"spread":0.2344850567659062,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006103305,0.0003920252,0.0002898921,0.0003921861,0.0003100162,0.000412602,0.0006018601,0.0003392992,0.001770769],"category_scores_gemma":[0.0002626359,0.0003928893,0.000320269,0.0002235883,0.0002980539,0.000213178,0.0003502881,0.000841363,0.001458268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002678825,"about_ca_system_score_gemma":0.0003203077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006072272,"about_ca_topic_score_gemma":0.001544032,"domain_scores_codex":[0.999541,0.00007981386,0.00008060818,0.00007900732,0.0001734172,0.00004615745],"domain_scores_gemma":[0.9997234,0.0000748167,0.00004105791,0.00009396081,0.00003425542,0.00003251264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004405202,0.00002459421,0.0002221439,0.00002633132,0.000004000646,0.0001011787,0.0000553316,0.00005579631,0.9981074,0.0003035586,0.00006165796,0.000993952],"study_design_scores_gemma":[0.00002984933,0.0001277073,0.003531494,0.00001414764,0.00002325071,0.0005831812,0.00002625831,0.000679874,0.9863247,0.00006641867,0.008588182,0.000004917866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9239017,0.002882585,0.05257693,0.0002641685,0.0001444827,0.001065735,0.00555918,0.0003981137,0.01320716],"genre_scores_gemma":[0.901136,0.004462133,0.04770449,0.0002000716,0.00005108942,0.001314069,0.01690097,0.0003642399,0.02786696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001770769,"threshold_uncertainty_score":0.005923808,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144120657","doi":"10.1038/nature15515","title":"Hallmarks of pluripotency","year":2015,"lang":"en","type":"review","venue":"Nature","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":405,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Howard Hughes Medical Institute","keywords":"Induced pluripotent stem cell; Biology; Stem cell; Epigenetics; Computational biology; Embryonic stem cell; Cellular differentiation; Cell biology; Cell potency; Functional genomics; Genomics; Genetics; Gene; Genome","authors":[{"name":"Alejandro De Los Angeles","is_ca":false},{"name":"Francesco Ferrari","is_ca":false},{"name":"Ruibin Xi","is_ca":false},{"name":"Yuko Fujiwara","is_ca":false},{"name":"Nissim Benvenisty","is_ca":false},{"name":"Hongkui Deng","is_ca":false},{"name":"Konrad Hochedlinger","is_ca":false},{"name":"Rudolf Jaenisch","is_ca":false},{"name":"Soohyun Lee","is_ca":false},{"name":"Harry G. Leitch","is_ca":false},{"name":"M. William Lensch","is_ca":false},{"name":"Ernesto Lujan","is_ca":false},{"name":"Duanqing Pei","is_ca":false},{"name":"Janet Rossant","is_ca":true},{"name":"Marius Wernig","is_ca":false},{"name":"Peter J. Park","is_ca":false},{"name":"George Q. Daley","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02578790651284873,"gpt":0.3503307312070522,"spread":0.3245428246942035,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007624878,0.0009720493,0.001176137,0.001521119,0.0003420731,0.001398827,0.001182334,0.001191684,0.003215073],"category_scores_gemma":[0.001172103,0.0002675325,0.0003461927,0.00164091,0.001367646,0.001708,0.001116924,0.002909551,0.001964326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008704288,"about_ca_system_score_gemma":0.001338347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008440076,"about_ca_topic_score_gemma":0.001580303,"domain_scores_codex":[0.9997399,0.00004325813,0.00004035171,0.00004137549,0.0001034972,0.00003151087],"domain_scores_gemma":[0.999643,0.0001669664,0.00004819594,0.00001527702,0.0000760726,0.0000506291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000545432,0.00002271415,0.0002416215,0.006424153,0.00003506086,0.0003209224,0.00005491409,0.000302844,0.002897547,0.01856745,0.06540077,0.9056775],"study_design_scores_gemma":[0.00000644966,0.00001570048,0.0002512898,0.0009957757,0.00002556691,0.0006386038,0.00003494816,0.00004469145,0.0005724077,0.00595636,0.9914477,0.00001052371],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001371989,0.9927202,0.0007990991,0.001283041,0.001439501,0.000008938724,0.00005708393,0.00002740777,0.003527555],"genre_scores_gemma":[0.001806886,0.9933497,0.0005815927,0.001235727,0.0008326654,0.00001606909,0.00009596249,0.000004928354,0.0020764],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003215073,"threshold_uncertainty_score":0.01075548,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2128877497","doi":"10.1172/jci41229","title":"Making the blastocyst: lessons from the mouse","year":2010,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":399,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Epiblast; Blastocyst; Biology; Embryonic stem cell; Embryo; Inner cell mass; Embryogenesis; Endoderm; Cell biology; Genetics; Andrology; Gastrulation; Gene; Medicine","authors":[{"name":"Katie Cockburn","is_ca":true},{"name":"Janet Rossant","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2590190069547085,"gpt":0.4856474473016056,"spread":0.2266284403468971,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001076002,0.0007995912,0.001013977,0.001508463,0.0002642782,0.0009905834,0.001064312,0.001374151,0.002083746],"category_scores_gemma":[0.0008141979,0.0002478411,0.00024447,0.001126277,0.001127611,0.00184293,0.0006634181,0.001779944,0.002354943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006136596,"about_ca_system_score_gemma":0.0005964623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001125148,"about_ca_topic_score_gemma":0.001842424,"domain_scores_codex":[0.9998425,0.00002478825,0.00002436764,0.00002775366,0.00007003622,0.0000105198],"domain_scores_gemma":[0.9997898,0.0000917203,0.00002148843,0.00001199775,0.00004808493,0.00003705037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008910307,0.00005769932,0.0002196023,0.005658499,0.00004137908,0.0006126502,0.0001830928,0.0004350319,0.005235932,0.01765196,0.03440771,0.9354074],"study_design_scores_gemma":[0.000021908,0.00006775598,0.0004465798,0.001313631,0.00003218272,0.001247869,0.00006867644,0.00006649731,0.001103426,0.004963678,0.9906551,0.00001255734],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002592599,0.9961494,0.0004760883,0.0006369615,0.0002979692,0.000004470792,0.000015909,0.00001525893,0.002144638],"genre_scores_gemma":[0.00122746,0.9960907,0.0007450181,0.000510287,0.0001819002,0.000008489294,0.00002096851,0.000004795472,0.001210405],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002083746,"threshold_uncertainty_score":0.006970823,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1597871117","doi":"10.1038/35093548","title":"Gene-trap mutagenesis: past, present and beyond","year":2001,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":398,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Leukemia and Lymphoma Society","keywords":"Mutagenesis; Biology; Gene; Genetics; Trap (plumbing); Embryonic stem cell; Computational biology; Function (biology); Mutation","authors":[{"name":"William L. Stanford","is_ca":true},{"name":"Jason B. Cohn","is_ca":true},{"name":"Sabine P. Cordes","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03526361935525488,"gpt":0.3542291505310795,"spread":0.3189655311758246,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003366162,0.001248418,0.001818432,0.001443955,0.0003503798,0.001439489,0.002640075,0.002112319,0.001858399],"category_scores_gemma":[0.00139665,0.0003917343,0.0004031294,0.001564141,0.00238801,0.00222857,0.0008274591,0.002690926,0.001730818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008205089,"about_ca_system_score_gemma":0.0008287055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009434323,"about_ca_topic_score_gemma":0.001814777,"domain_scores_codex":[0.9993775,0.0001619579,0.00005518254,0.0001206161,0.0002266062,0.00005818164],"domain_scores_gemma":[0.9986869,0.0008427388,0.00008100146,0.00008808202,0.0002003955,0.0001009979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001778895,0.0001139474,0.0005842727,0.007415995,0.00006777155,0.0004604972,0.0001195156,0.000675301,0.01632453,0.02143455,0.02798304,0.9246426],"study_design_scores_gemma":[0.00005225007,0.0001520021,0.001437309,0.001885626,0.0001236051,0.002729173,0.00013249,0.0004357244,0.008999605,0.01448917,0.9695052,0.00005792349],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003191369,0.9932853,0.003734982,0.0009292022,0.0003719198,0.000005848214,0.00002080419,0.00004791268,0.001284927],"genre_scores_gemma":[0.002767287,0.9917378,0.002985687,0.0008599414,0.0002598136,0.00001428315,0.00003448199,0.00001274135,0.001327865],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003366162,"threshold_uncertainty_score":0.01780218,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2010122622","doi":"10.1016/j.cell.2011.08.023","title":"An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming","year":2011,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":394,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; Howard Hughes Medical Institute","keywords":"Biology; Reprogramming; Homeobox protein NANOG; Induced pluripotent stem cell; Embryonic stem cell; Transcription factor; Cell biology; Alternative splicing; Rex1; Cellular differentiation; Somatic cell; Nanog Homeobox Protein; Cell potency; Stem cell; RNA splicing; Regulation of gene expression; Genetics; Gene isoform; Gene; RNA","authors":[{"name":"Mathieu Gabut","is_ca":true},{"name":"Payman Samavarchi‐Tehrani","is_ca":true},{"name":"Xinchen Wang","is_ca":true},{"name":"Valentina Slobodeniuc","is_ca":true},{"name":"Dave O’Hanlon","is_ca":true},{"name":"Hoon‐Ki Sung","is_ca":true},{"name":"Manuel Alvarez","is_ca":true},{"name":"Shaheynoor Talukder","is_ca":true},{"name":"Qun Pan","is_ca":true},{"name":"Esteban O. Mazzoni","is_ca":false},{"name":"Stéphane Nedelec","is_ca":false},{"name":"Hynek Wichterle","is_ca":false},{"name":"Knut Woltjen","is_ca":true},{"name":"Timothy R. Hughes","is_ca":true},{"name":"Peter W. Zandstra","is_ca":true},{"name":"András Nagy","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Benjamin J. Blencowe","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01975692129787041,"gpt":0.2519614517897785,"spread":0.2322045304919081,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004100197,0.0003385391,0.0002732148,0.0002717683,0.0003089533,0.000738972,0.0003208352,0.000469437,0.001806042],"category_scores_gemma":[0.0002908,0.0002250536,0.0004497174,0.000176657,0.0003820793,0.0005026758,0.0003059031,0.0008302456,0.0009423133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002991913,"about_ca_system_score_gemma":0.0001961507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001368692,"about_ca_topic_score_gemma":0.0003111455,"domain_scores_codex":[0.9997287,0.00004494816,0.00002606205,0.00008458216,0.00007431812,0.00004124046],"domain_scores_gemma":[0.9997937,0.00006155139,0.00004683963,0.00003390142,0.00002904802,0.00003496943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006457318,0.00001102327,0.0002332646,0.00001673005,0.000005540057,0.0001828648,0.00002037559,0.00007109258,0.9932219,0.002540157,0.0001241389,0.003508315],"study_design_scores_gemma":[0.00002261525,0.0001097396,0.001995487,0.000006845056,0.00003002853,0.00107484,0.00003298716,0.00179615,0.984736,0.001623594,0.008559376,0.00001232859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9233991,0.003594569,0.05911302,0.000877354,0.0007085166,0.0000704296,0.0006156242,0.0007744793,0.0108468],"genre_scores_gemma":[0.9812211,0.00123212,0.01035211,0.0002666362,0.0001274139,0.0000273551,0.0006344824,0.0001976899,0.005941119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001806042,"threshold_uncertainty_score":0.006041825,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2003211588","doi":"10.1038/nbt.1788","title":"Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells","year":2011,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":391,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Institute on Aging","keywords":"Endoderm; Induced pluripotent stem cell; Biology; Embryonic stem cell; Cell biology; Stem cell; Foregut; Cellular differentiation; Anatomy; Genetics; Gene","authors":[{"name":"Michael D. Green","is_ca":false},{"name":"Antonia F. Chen","is_ca":false},{"name":"M. Cristina Nostro","is_ca":true},{"name":"Sunita L. D’Souza","is_ca":false},{"name":"Christoph Schaniel","is_ca":false},{"name":"Ihor R. Lemischka","is_ca":false},{"name":"Valerie Gouon–Evans","is_ca":false},{"name":"Gordon Keller","is_ca":true},{"name":"Hans Snoeck","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03415710805227472,"gpt":0.2673115264546517,"spread":0.233154418402377,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003568242,0.000284636,0.000265696,0.0003210133,0.0002965992,0.0003256065,0.0003166654,0.000360903,0.002629472],"category_scores_gemma":[0.0001680881,0.0002924739,0.0003742752,0.0001664617,0.0001405116,0.0001969438,0.0004103919,0.0008222883,0.001336287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001337795,"about_ca_system_score_gemma":0.0002429077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002845228,"about_ca_topic_score_gemma":0.0007368722,"domain_scores_codex":[0.9998597,0.00001456144,0.0000225939,0.00002168467,0.00005848465,0.00002290182],"domain_scores_gemma":[0.9998772,0.00002448596,0.0000160455,0.0000277394,0.00002466815,0.00002983512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005962458,0.00001631805,0.0002097045,0.00005154643,0.000005995447,0.0001092021,0.00002744263,0.00006572474,0.9956097,0.0006311193,0.0001755262,0.003038151],"study_design_scores_gemma":[0.00004061726,0.0001114759,0.004257741,0.00001246972,0.00003157112,0.0005586582,0.00002490043,0.001012051,0.9727784,0.0002062013,0.02095469,0.00001123809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8457531,0.003865977,0.1166263,0.0006928282,0.0006813951,0.001809029,0.01063986,0.0005899888,0.01934165],"genre_scores_gemma":[0.869352,0.003075373,0.08810713,0.0003149829,0.00009700013,0.0006424609,0.01116215,0.0001628208,0.02708604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002629472,"threshold_uncertainty_score":0.008796394,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2775939089","doi":"10.24966/ggs-2485/100001","title":"Principles of Development","year":2016,"lang":"en","type":"article","venue":"Genetics & Genomic Sciences","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":390,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Field (mathematics); Computer science; Library science; Data science; History","authors":[{"name":"Sperber Gh","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04002624773239721,"gpt":0.2857157131938058,"spread":0.2456894654614086,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003783367,0.001163918,0.0007988898,0.001500442,0.002478084,0.00822795,0.002453864,0.002594727,0.02860257],"category_scores_gemma":[0.004709398,0.0005312529,0.0007367339,0.00121307,0.01131456,0.003838046,0.004597345,0.00452178,0.02637559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003786961,"about_ca_system_score_gemma":0.007280529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003309618,"about_ca_topic_score_gemma":0.004268603,"domain_scores_codex":[0.996254,0.001036247,0.0002722039,0.0006483248,0.001480356,0.0003089055],"domain_scores_gemma":[0.9980407,0.0005328464,0.000114292,0.0004521901,0.0006318009,0.000228182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00001087752,0.00001510912,0.000151701,0.0002295799,0.000008646038,0.00007024907,0.0008316543,0.0002643409,0.0002350565,0.8730642,0.06653891,0.05857964],"study_design_scores_gemma":[0.00000454392,0.00001317524,0.00007984086,0.0001782762,0.000003032916,0.0001356941,0.000166717,0.00007806784,0.0001426139,0.1219792,0.8772125,0.000006461299],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.0007164052,0.01610646,0.05858413,0.01510119,0.002559276,0.0003149543,0.0004292332,0.0005753805,0.905613],"genre_scores_gemma":[0.07330551,0.03880957,0.1120581,0.01222553,0.001308347,0.002264625,0.0007478229,0.0006593994,0.7586212],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02860257,"threshold_uncertainty_score":0.09568512,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}