{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":1849,"total_is_capped":false,"direct_labels_cover":1,"predictions_cover":1849,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"ed79dd1cdf3d","filters":{"topic":"Regulation of Appetite and Obesity"}},"results":[{"id":"W2147311167","doi":"10.1038/ng.686","title":"Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index","year":2010,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":2979,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; McMaster University; Montreal Heart Institute","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Human Genome Research Institute; National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; National Institute on Aging; Cambridge Institute for Medical Research, University of Cambridge; Medical Research Council; Goddard Space Flight Center; National Institutes of Health; Diabetesforeningen; Diabetestutkimussäätiö; H. Lundbeck A/S; Hjartavernd; Institut de Cardiologie de Montréal; Fondation Institut de Cardiologie de Montréal; Paavo Nurmen Säätiö; Svenska Kulturfonden; National Health and Medical Research Council; Oulun Yliopisto; Sydäntutkimussäätiö; National Institute of Mental Health; Göteborgs Läkaresällskap; Technische Universität Dresden; Augustinus Fonden; Vetenskapsrådet; National Institute on Alcohol Abuse and Alcoholism; Stockholms Läns Landsting; GlaxoSmithKline; Signe ja Ane Gyllenbergin Säätiö; Fondation Leenaards; Päivikki ja Sakari Sohlbergin Säätiö; National Institute of Diabetes and Digestive and Kidney Diseases; Norwegian Institute of Public Health; Helsingin ja Uudenmaan Sairaanhoitopiiri; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Juho Vainion Säätiö; British Heart Foundation; Bundesministerium für Bildung und Forschung; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Institut National de la Santé et de la Recherche Médicale; AstraZeneca; European Commission; Finska Läkaresällskapet; Yrjö Jahnssonin Säätiö; Cancerfonden; Juvenile Diabetes Research Foundation International; Diabetes UK; Lastentautien Tutkimussäätiö; National Institute for Health and Care Research; Wellcome Trust; Cancer Research UK; Erasmus Medisch Centrum; Stiftelsen för Strategisk Forskning; Healthway; Scottish Government; National Cancer Institute; Lundbeckfonden; Foundation for Cardiovascular Research; National Science Foundation; Fondation Leducq; Centre for Medical Systems Biology; Novo Nordisk; Hjärt-Lungfonden; Agency for Science, Technology and Research; Jalmari ja Rauha Ahokkaan Säätiö; Kela; Svenska Läkaresällskapet; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Deutsche Forschungsgemeinschaft; Hjerteforeningen; Biomedicum Helsinki-säätiö; Donald W. Reynolds Foundation; Chinese Society of Clinical Oncology; Amgen","keywords":"Biology; Body mass index; Genetics; Genome-wide association study; Single-nucleotide polymorphism; Obesity; Genetic association; Quantitative trait locus; SNP; Gene; Genotype; Endocrinology","retraction":null,"screen_n_in":null,"score":{"opus":0.0230115211810428,"gpt":0.3045985023804711,"spread":0.2815869811994284,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003148712,0.0001638322,0.000247898,0.0001316566,0.0001015098,0.00006126655,0.0003184072,0.0006600855,0.000147],"category_scores_gemma":[0.001270389,0.0001406373,0.00007551705,0.0006461398,0.00006200916,0.00009295066,0.00004832674,0.0008050406,0.00001233016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000541823,"about_ca_system_score_gemma":0.0001531443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001345647,"about_ca_topic_score_gemma":0.0000658734,"domain_scores_codex":[0.9981385,0.0001043169,0.0002804076,0.00032178,0.0008894058,0.0002655292],"domain_scores_gemma":[0.9985984,0.0002444907,0.0005123031,0.0003134958,0.0002182656,0.0001130506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0000142457,0.00006382065,0.6057373,0.000006065676,0.00004351039,0.000002541078,0.00005188695,0.0001989869,0.3845299,0.00006581067,0.008914422,0.0003715608],"study_design_scores_gemma":[0.0003777781,0.00005908385,0.5504283,0.00001009556,0.00005287073,0.000001019154,0.000004736567,0.0001808441,0.4444974,0.0006176353,0.003654154,0.0001161249],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965159,0.00006853105,0.0001417601,0.0004238185,0.0002713727,0.0001722332,0.00004697923,0.00004913332,0.002310318],"genre_scores_gemma":[0.9942241,0.00003346117,0.001195965,0.0004450182,0.0002110974,0.00000151087,0.00002848272,0.00001997539,0.00384037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05996751,"threshold_uncertainty_score":0.5735024,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1990095603","doi":"10.1016/s0896-6273(03)00063-1","title":"The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis","year":2003,"lang":"en","type":"article","venue":"Neuron","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":1664,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; Merck; National Institute of Mental Health; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Ghrelin; Energy homeostasis; Mechanism (biology); Neuroscience; Homeostasis; Hypothalamus; Action (physics); Mechanism of action; Biology; Cell biology; Endocrinology; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.04038572855942681,"gpt":0.2480156516681326,"spread":0.2076299231087058,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002735125,0.00007054117,0.00008759691,0.00003131053,0.0001341325,0.0000226888,0.0001073395,0.00004011856,0.000002460141],"category_scores_gemma":[0.0003321685,0.00004745865,0.0000308717,0.0002424683,0.00008922394,0.00008772687,0.00001499545,0.00007500733,3.263963e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001150213,"about_ca_system_score_gemma":0.00001881039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003511291,"about_ca_topic_score_gemma":0.00002873902,"domain_scores_codex":[0.9991392,0.0001783911,0.0002100624,0.0001610551,0.0001937128,0.000117543],"domain_scores_gemma":[0.9992514,0.0003821929,0.0001584393,0.0001718006,0.00002208917,0.00001410798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001014621,0.00004385219,0.0004739915,0.000008613345,7.91125e-7,5.216266e-7,0.00007056004,0.00008920673,0.8226109,0.1713934,0.000006032316,0.00529203],"study_design_scores_gemma":[0.0002252208,0.00006865302,0.03421155,0.00001486599,0.000005978486,0.00002033813,0.0001533904,0.001805243,0.9551694,0.007970079,0.0003066216,0.00004864357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972824,0.00003267999,0.001914387,0.0002044477,0.00006167204,0.00009024269,0.00001084934,0.000007648241,0.0003957111],"genre_scores_gemma":[0.9997119,0.0001847011,0.00001821713,0.00004640841,0.000008933258,0.000003968798,0.00000187528,0.000004979641,0.00001897943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1634233,"threshold_uncertainty_score":0.1935308,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2039663505","doi":"10.1017/s0954422410000168","title":"High-fat diet-induced obesity in animal models","year":2010,"lang":"en","type":"review","venue":"Nutrition Research Reviews","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":1084,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Obesity; Ghrelin; Leptin; Endocrinology; Adipose tissue; Internal medicine; Hormone; Dietary fat; Biology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.3923176459499846,"gpt":0.463150933193719,"spread":0.07083328724373439,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004140885,0.0005589488,0.002553677,0.001082523,0.0003916019,0.0002591723,0.001287203,0.000842184,0.0005012554],"category_scores_gemma":[0.001732055,0.0004540445,0.0007259653,0.002401106,0.0002527998,0.0005934528,0.0003810671,0.003411337,0.003059715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003290542,"about_ca_system_score_gemma":0.0002389842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007115062,"about_ca_topic_score_gemma":0.00008585309,"domain_scores_codex":[0.9905316,0.004229563,0.001495517,0.001380613,0.0013859,0.0009767984],"domain_scores_gemma":[0.9968225,0.0009419561,0.000440668,0.001254354,0.0001993184,0.0003412187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005307686,0.001204337,0.00000149666,0.0332602,0.000004192689,0.00009604636,0.00002224313,2.802597e-7,0.001719822,0.0153321,0.009575661,0.9387305],"study_design_scores_gemma":[0.0003301966,0.0002232387,0.000005597891,0.01860505,0.00002459561,0.00001536827,0.00000220279,0.00003146287,0.0006776602,0.003162494,0.9765289,0.0003932459],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007732672,0.9902797,0.00001087671,0.0002345587,0.0002416962,0.00597188,0.00006059657,0.00007260635,0.002354805],"genre_scores_gemma":[0.0001650471,0.9964753,0.0003862361,0.00007608279,0.0006725953,0.001382661,0.00008079316,0.00006753307,0.0006937636],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9669532,"threshold_uncertainty_score":0.9997911,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4211061743","doi":"10.1016/j.molmet.2015.03.005","title":"Ghrelin","year":2015,"lang":"en","type":"review","venue":"Molecular Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":1008,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Deutsches Zentrum für Diabetesforschung; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Drug Abuse; National Institute of General Medical Sciences; National Institute of Mental Health; National Institute on Aging; Science Foundation Ireland; National Institutes of Health; Novo Nordisk Fonden; Wellcome Trust; Alexander von Humboldt-Stiftung","keywords":"Ghrelin; Endocrinology; Internal medicine; Medicine; Biology; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.07526801418775958,"gpt":0.3460793995375132,"spread":0.2708113853497536,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003183799,0.0004202226,0.001388139,0.0002303343,0.00007198085,0.00009478391,0.0006437645,0.0002331496,0.0001291284],"category_scores_gemma":[0.000324134,0.0003394904,0.0006042551,0.0005567007,0.00008247089,0.00008761826,0.0001922027,0.0003602618,0.002463862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003631865,"about_ca_system_score_gemma":0.0002524902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004587524,"about_ca_topic_score_gemma":2.386599e-7,"domain_scores_codex":[0.9974391,0.0004845255,0.0004686255,0.0006696853,0.0006033506,0.0003347273],"domain_scores_gemma":[0.9986306,0.00005903795,0.0002719487,0.0007706606,0.00005688767,0.0002108899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001200616,0.00003175683,1.877472e-8,0.0007765465,0.00001322309,0.0001177303,0.00001160134,0.000002128811,0.000236243,0.01376691,0.001437073,0.9836056],"study_design_scores_gemma":[0.0001145363,0.00000507104,4.242318e-7,0.0004849893,0.0003075674,0.00004973794,5.306163e-7,0.00000373172,0.001796133,0.0009499164,0.99594,0.0003473164],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001488072,0.9883351,0.0002487383,0.00003004425,0.0006540053,0.00048564,0.00003007947,0.0001201158,0.01008139],"genre_scores_gemma":[0.000005399731,0.9970792,0.0002987261,0.0003659584,0.0002547333,0.00004246905,0.00002619022,0.00007941471,0.001847898],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.994503,"threshold_uncertainty_score":0.9999057,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2114496307","doi":"10.1152/physrev.2000.80.3.979","title":"Corticotropin Releasing Hormone and Proopiomelanocortin Involvement in the Cutaneous Response to Stress","year":2000,"lang":"en","type":"review","venue":"Physiological Reviews","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":771,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"","keywords":"Proopiomelanocortin; Receptor; Corticotropin-releasing hormone; Endocrinology; Internal medicine; Melanocyte-stimulating hormone; Hormone; Immune system; Adrenocorticotropic hormone; Neuropeptide; Downregulation and upregulation; Proinflammatory cytokine; Biology; Chemistry; Immunology; Gene; Inflammation; Medicine; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.133702160114989,"gpt":0.3629632379649478,"spread":0.2292610778499587,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000267939,0.0004152058,0.001577661,0.0001176547,0.0001323287,0.00009038813,0.0005912555,0.0001604136,0.00006234494],"category_scores_gemma":[0.001429338,0.000208083,0.0002693394,0.0006836634,0.0001224301,0.00005184592,0.0001669453,0.0004412338,0.0003453446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006987095,"about_ca_system_score_gemma":0.00004785183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006410894,"about_ca_topic_score_gemma":0.000002364143,"domain_scores_codex":[0.994714,0.002795345,0.001022992,0.0007927369,0.0002922811,0.0003826474],"domain_scores_gemma":[0.9980882,0.0008105612,0.0003773104,0.0005934106,0.00001071154,0.0001198523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001240023,0.0001622202,0.000001332457,0.001787892,0.000002598023,0.00008016948,0.0001001105,0.00000271353,0.001548953,0.0001236735,0.001548051,0.9945183],"study_design_scores_gemma":[0.00007042169,0.0003540961,0.0004187073,0.004239956,0.0000412997,0.00004161994,0.000004640593,0.000004103364,0.00001886121,0.0001147072,0.9944307,0.0002608536],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01757397,0.9786541,0.000003113179,0.0001490824,0.00003302039,0.003441243,0.00001893925,0.00002852713,0.00009801662],"genre_scores_gemma":[0.0003994139,0.997865,0.00008184056,0.0009840692,0.00009159918,0.0004075392,0.00001388466,0.00001756333,0.0001391102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9942575,"threshold_uncertainty_score":0.848538,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144489715","doi":"10.1073/pnas.0305930101","title":"Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":748,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging; Canadian Institutes of Health Research; Curtis and Doris K. Hankamer Foundation; Yale University","keywords":"Ghrelin; Endocrinology; Internal medicine; Growth hormone secretagogue receptor; Appetite; Leptin; Receptor; Hormone; Secretagogue; Agonist; Biology; Insulin; Stimulation; Medicine; Obesity","retraction":null,"screen_n_in":null,"score":{"opus":0.03595600838744865,"gpt":0.2802989323521637,"spread":0.2443429239647151,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009295132,0.0001385571,0.000197381,0.0001359228,0.0003553194,0.00003495761,0.0007408029,0.0001087437,0.00001142602],"category_scores_gemma":[0.001857843,0.00008395276,0.00008029789,0.001309084,0.001722282,0.0008911604,0.0001679807,0.0001936995,0.000003991834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003136906,"about_ca_system_score_gemma":0.00004996488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004029321,"about_ca_topic_score_gemma":9.525388e-8,"domain_scores_codex":[0.9974104,0.00001856655,0.0004764469,0.0003566121,0.001562073,0.0001758956],"domain_scores_gemma":[0.9985358,0.0002953236,0.0007081051,0.00001894145,0.0003949286,0.00004693466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006136221,0.00005979741,0.001251301,0.00004242015,0.000006048829,7.407586e-9,0.000763384,0.0001704975,0.8928617,0.1041623,0.0005678243,0.00005336465],"study_design_scores_gemma":[0.0004938468,0.0001133657,0.06829628,0.00007821663,0.00001274913,0.00000480912,0.0001256382,0.001014609,0.8166164,0.1129825,0.000161611,0.0001000157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831511,0.0002952277,0.00001496918,0.01443352,0.00001902544,0.0003029325,0.00004191037,0.00001850865,0.001722783],"genre_scores_gemma":[0.9972457,0.0007979267,0.0009769112,0.0008396315,0.00006428982,0.000005946061,5.087649e-7,0.000006391742,0.00006269264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07624531,"threshold_uncertainty_score":0.6345819,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2048717385","doi":"10.1210/jc.2004-0165","title":"Metabolic and Body Composition Factors in Subgroups of Obesity: What Do We Know?","year":2004,"lang":"en","type":"review","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":728,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Obesity; Adipose tissue; Medicine; Metabolic syndrome; Body mass index; Endocrinology; Internal medicine; Disease; Insulin resistance; Diabetes mellitus; Etiology; Physiology","retraction":null,"screen_n_in":null,"score":{"opus":0.08235053056369938,"gpt":0.3911686843696742,"spread":0.3088181538059748,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001991476,0.0004898384,0.004542295,0.0006014648,0.0001163272,0.00006872453,0.001059183,0.0004433636,0.00005243231],"category_scores_gemma":[0.0008867893,0.0002891665,0.001078416,0.0005419787,0.001000491,0.0006144037,0.0002834317,0.002029417,0.00001751621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002738204,"about_ca_system_score_gemma":0.0003597203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001862488,"about_ca_topic_score_gemma":0.000004195955,"domain_scores_codex":[0.9914386,0.003497027,0.003604149,0.0004168052,0.0005670905,0.0004763255],"domain_scores_gemma":[0.9914177,0.00413299,0.003548622,0.0005533347,0.0001483733,0.0001989647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000191046,0.000851831,0.0003949202,0.001463623,0.0002513304,0.0001246878,0.0002908309,0.00002662107,0.000273945,0.01873094,0.00002785437,0.9773723],"study_design_scores_gemma":[0.001694544,0.0002194239,0.00854987,0.007954127,0.002025779,0.0009665155,0.00008025243,0.000002606301,0.001964434,0.003808226,0.9723997,0.0003345862],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1284265,0.8693159,0.0000180446,0.0004821147,0.001332052,0.0003756982,0.00001074824,0.00001133668,0.00002753712],"genre_scores_gemma":[0.0188604,0.9803795,0.00007909562,0.0001241407,0.0004819726,0.000002794295,0.000001896386,0.00003465875,0.00003559197],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9770378,"threshold_uncertainty_score":0.9999561,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1987555746","doi":"10.1016/j.cmet.2008.03.007","title":"Ghrelin Modulates Brain Activity in Areas that Control Appetitive Behavior","year":2008,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":683,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Ghrelin; Endocrinology; Internal medicine; Neuroscience; Hypothalamus; Feeding behavior; Medicine; Biology; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.02754085374881158,"gpt":0.2442697742335529,"spread":0.2167289204847414,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963693,0.0002140679,0.0003420705,0.0001651824,0.0001804573,0.00003267618,0.0002523457,0.000120829,0.0001373116],"category_scores_gemma":[0.0001545301,0.0002017287,0.0001233777,0.0002849051,0.0001917791,0.0003469855,0.00005529551,0.0002472817,0.0001927853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002811479,"about_ca_system_score_gemma":0.00004739978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009027407,"about_ca_topic_score_gemma":0.00001706151,"domain_scores_codex":[0.9983159,0.0002520555,0.0001958327,0.0005117814,0.0003517008,0.0003727292],"domain_scores_gemma":[0.9990978,0.0002788999,0.0001245309,0.0003381153,0.00003242068,0.000128298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001005291,0.0005613162,0.03809084,0.00001053389,0.000002817149,0.0001667715,0.0005480621,0.0002544903,0.9559594,0.001045658,0.0003546514,0.002904914],"study_design_scores_gemma":[0.0009661097,0.00001134002,0.463762,0.000005555649,0.000009219665,0.0000120246,0.00001276496,0.0003933072,0.5297773,0.0001679472,0.00473034,0.0001520631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949309,0.000204715,0.0003316068,0.0005207051,0.0003056675,0.0004502106,0.00002321332,0.000081197,0.003151754],"genre_scores_gemma":[0.9966807,0.000178946,0.00007240788,0.0007665667,0.0001203067,0.00004659345,0.000002579855,0.00002357593,0.002108368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4261821,"threshold_uncertainty_score":0.8226256,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2135340140","doi":"10.1128/mcb.23.22.7973-7981.2003","title":"Deletion of Ghrelin Impairs neither Growth nor Appetite","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":638,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute on Aging; National Institutes of Health; Canadian Institutes of Health Research; Curtis and Doris K. Hankamer Foundation","keywords":"Ghrelin; Endocrinology; Appetite; Internal medicine; Leptin; Biology; Energy homeostasis; Hormone; Insulin; Obesity; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.008736081649454103,"gpt":0.2200785618679255,"spread":0.2113424802184714,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001652182,0.0001035264,0.0001437561,0.00007490569,0.00005531868,0.000009763591,0.0000886085,0.0001055065,0.00008508353],"category_scores_gemma":[0.0001208296,0.00009048782,0.0000654769,0.0001500192,0.0001537561,0.0000287855,0.00002862001,0.00006696107,0.00002583422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005708371,"about_ca_system_score_gemma":0.00001587488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001641646,"about_ca_topic_score_gemma":0.000001374651,"domain_scores_codex":[0.9990966,0.0002056583,0.0001661584,0.000273824,0.0000823385,0.0001754612],"domain_scores_gemma":[0.9996423,0.00003270659,0.00007137558,0.000160752,0.00003540506,0.0000575105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001160756,0.00003244908,0.003204894,0.00001157675,0.000003315203,0.000007763819,0.00002277257,0.000007275374,0.904977,0.09139759,0.00001247601,0.0003112891],"study_design_scores_gemma":[0.0002898603,0.0001434025,0.0005249373,0.000006581984,0.000007440553,0.00001317706,0.00000977833,0.00007656026,0.9865529,0.006558092,0.00571556,0.0001017383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975638,0.0003182263,0.01858791,0.0001271265,0.00007359871,0.0001081584,0.000004620175,0.00001894139,0.005123377],"genre_scores_gemma":[0.9990268,0.00007444968,0.000369599,0.0003581735,0.00001286205,0.000003365519,0.000006468993,0.00001019453,0.00013811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0848395,"threshold_uncertainty_score":0.3689986,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2050684182","doi":"10.1016/j.neuron.2006.09.006","title":"Leptin Regulation of the Mesoaccumbens Dopamine Pathway","year":2006,"lang":"en","type":"article","venue":"Neuron","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":628,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Leptin; Ventral tegmental area; Nucleus accumbens; Internal medicine; Leptin receptor; Endocrinology; Dopamine; Amphetamine; Hypothalamus; Receptor; Chemistry; Neuroscience; Biology; Dopaminergic; Medicine; Obesity","retraction":null,"screen_n_in":null,"score":{"opus":0.01707171886931706,"gpt":0.2248764249208574,"spread":0.2078047060515403,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000615623,0.00006654054,0.0000715831,0.00002841785,0.00008807184,0.0000141633,0.0001600302,0.00003063693,0.00007345555],"category_scores_gemma":[0.00007760512,0.00004761646,0.00005696099,0.0002004647,0.00007344481,0.00008585219,0.00004640206,0.00006065152,0.00002757758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009411577,"about_ca_system_score_gemma":0.00001335387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003066632,"about_ca_topic_score_gemma":0.00001836875,"domain_scores_codex":[0.9992208,0.00008405823,0.0001645161,0.0001765226,0.0002483141,0.0001057981],"domain_scores_gemma":[0.9994917,0.00007145821,0.0001160443,0.000284788,0.00002109362,0.00001492474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007052478,0.00003566885,0.003155319,0.000004653092,1.688936e-7,7.165935e-7,0.00001045149,0.0006016712,0.9854854,0.009292751,0.0005254282,0.0008807175],"study_design_scores_gemma":[0.00009827438,0.00001754464,0.3539113,0.000004223445,0.000001537781,0.000002802466,9.497703e-7,0.0003790367,0.6320845,0.0006974913,0.01277025,0.00003215398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779899,0.000005536966,0.00004274241,0.0005744439,0.0001760938,0.0001187593,0.000004486858,0.00003432515,0.02105371],"genre_scores_gemma":[0.9953684,0.000002159639,0.00002923151,0.0001662347,0.00008624777,0.000001589394,0.000001285959,0.000008051823,0.00433676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3534009,"threshold_uncertainty_score":0.1941743,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2075182826","doi":"10.1016/j.ygcen.2004.11.001","title":"Neuropeptides and the control of food intake in fish","year":2004,"lang":"en","type":"review","venue":"General and Comparative Endocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":579,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"York University; University of Guelph; University of Alberta; University of British Columbia; Memorial University of Newfoundland","funders":"Killam Trusts; Natural Sciences and Engineering Research Council of Canada; Ministerio de Educación, Cultura y Deporte; University of Alberta","keywords":"Orexigenic; Internal medicine; Endocrinology; Ghrelin; Neuropeptide Y receptor; Biology; Hypothalamus; Orexin; Cart; Neuropeptide; Appetite; Leptin; Cocaine and amphetamine regulated transcript; Cholecystokinin; Bombesin; Galanin; Melanin-concentrating hormone; Hormone; Receptor; Medicine; Obesity","retraction":null,"screen_n_in":null,"score":{"opus":0.09145048074080933,"gpt":0.3159993260407539,"spread":0.2245488452999445,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005973535,0.0002161748,0.001131346,0.0001008174,0.00007159642,0.00001966826,0.0001819546,0.00005815379,0.000008928815],"category_scores_gemma":[0.00003935625,0.0001267634,0.00009894276,0.0001430165,0.0007822439,0.00004221534,0.0001104958,0.0002459557,0.000003007692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001112759,"about_ca_system_score_gemma":0.00004546396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000237263,"about_ca_topic_score_gemma":0.00007290683,"domain_scores_codex":[0.998414,0.0005871141,0.0003796112,0.0003440156,0.00006722838,0.0002079846],"domain_scores_gemma":[0.9991665,0.000416779,0.0002139002,0.0001532562,0.00001729997,0.00003219676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001969131,0.0001215047,0.0001110191,0.002108768,0.00008625206,0.00004832763,0.0005101307,0.0001102088,0.0002427947,0.771637,0.0001116791,0.2247155],"study_design_scores_gemma":[0.004169349,0.0004675143,0.001267639,0.0009709133,0.0001440391,0.0003894132,0.00002857667,0.00008112206,0.001699369,0.005138067,0.9852864,0.0003575975],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06079469,0.9370022,0.00002267128,0.0002127337,0.0001094779,0.0006651859,0.0000427758,0.00001289751,0.001137363],"genre_scores_gemma":[0.1154135,0.8840879,0.00001503133,0.0002372782,0.00004784996,0.00004279842,0.000003783048,0.000004489617,0.0001474258],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9851747,"threshold_uncertainty_score":0.5169261,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1985475058","doi":"10.1172/jci17490","title":"The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":575,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsches Krebsforschungszentrum; U.S. Public Health Service; Amgen","keywords":"Leptin; Endocrinology; Internal medicine; Hypothalamic–pituitary–thyroid axis; Starvation; Hormone; Medicine; Leptin receptor; Hypothalamus; Appetite; Obesity; Adipokine; Biology; Thyroid hormones","retraction":null,"screen_n_in":null,"score":{"opus":0.1463855366373734,"gpt":0.3830263003065387,"spread":0.2366407636691654,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003076966,0.00006972937,0.0002115847,0.0001160503,0.00007537334,0.00004475255,0.0001541784,0.00002963595,0.00000218823],"category_scores_gemma":[0.004446415,0.00004390725,0.00004891047,0.0003739613,0.0001044222,0.0003101923,0.00001347695,0.0002838905,9.360569e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001280743,"about_ca_system_score_gemma":0.0001050785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001874518,"about_ca_topic_score_gemma":0.0001021116,"domain_scores_codex":[0.9970753,0.00104569,0.001251899,0.0001316923,0.0003739111,0.0001215753],"domain_scores_gemma":[0.9976746,0.001529276,0.0005135445,0.0001146073,0.00009035065,0.00007758579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007055538,0.0003264959,0.678948,0.00003012317,0.00001092882,0.00001924171,0.004921926,0.01361666,0.141013,0.05864846,0.00007674135,0.101683],"study_design_scores_gemma":[0.0005540715,0.0003348801,0.9310153,0.00004229727,0.000008301765,0.00001557839,0.0004965732,0.004553147,0.04455469,0.01669462,0.001677224,0.00005336556],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954097,0.0001038904,0.0002315205,0.003801086,0.00009684829,0.0002089958,8.191109e-7,0.000002242034,0.0001448882],"genre_scores_gemma":[0.9979945,0.0003715999,0.0007060175,0.0008454304,0.00006672616,0.000002781954,3.653018e-7,0.000004785493,0.000007770872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2520673,"threshold_uncertainty_score":0.5323095,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2108823659","doi":"10.1210/jc.2002-021309","title":"Plasma Acylation-Stimulating Protein, Adiponectin, Leptin, and Ghrelin before and after Weight Loss Induced by Gastric Bypass Surgery in Morbidly Obese Subjects","year":2003,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":505,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Royal Victoria Hospital; McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Adiponectin; Ghrelin; Internal medicine; Endocrinology; Leptin; Weight loss; Medicine; Insulin; Apolipoprotein B; Insulin resistance; Gastric bypass surgery; Obesity; Gastric bypass; Hormone; Cholesterol","retraction":null,"screen_n_in":null,"score":{"opus":0.03629193529285671,"gpt":0.3139125196178096,"spread":0.2776205843249528,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002280847,0.000253647,0.0008405086,0.000279763,0.0001651651,0.00004385073,0.0002371287,0.0001940476,0.0000733919],"category_scores_gemma":[0.006916066,0.0001745355,0.0001574773,0.0004060132,0.0004154487,0.0003938451,0.00009868306,0.001098906,0.00001085039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001625852,"about_ca_system_score_gemma":0.0001374937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002513393,"about_ca_topic_score_gemma":0.00005237263,"domain_scores_codex":[0.9953876,0.001757623,0.001617317,0.0003492585,0.0003836813,0.0005045666],"domain_scores_gemma":[0.9951366,0.0033003,0.0009399234,0.0002645815,0.000149328,0.0002093108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002461197,0.0006586011,0.8604475,0.00005687456,0.0001150635,0.0004503132,0.0006170967,0.0001598181,0.09677022,0.003135023,0.000298829,0.03482941],"study_design_scores_gemma":[0.003342742,0.0002653136,0.9484958,0.00008291307,0.0001063213,0.001003858,0.00004407137,0.0002472838,0.0397109,0.002069155,0.004387441,0.0002442223],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963598,0.0009764169,0.00004807797,0.00184723,0.0004164058,0.0002192628,0.000003488186,0.00001603331,0.0001133457],"genre_scores_gemma":[0.9976658,0.001098236,0.0002714701,0.0005843993,0.0002490678,0.000007191156,4.841236e-7,0.00002314133,0.0001001656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08804823,"threshold_uncertainty_score":0.8279677,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2024734221","doi":"10.1038/nm1072","title":"Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3","year":2004,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":491,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"","keywords":"SOCS3; Leptin; Leptin receptor; Endocrinology; Internal medicine; Biology; Haploinsufficiency; Receptor; Hormone; Mediator; Signal transduction; Medicine; Obesity; STAT3; Cell biology; Phenotype; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01238488439257713,"gpt":0.2628228227293928,"spread":0.2504379383368157,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003749414,0.0001035009,0.0002611818,0.0001263464,0.00003902933,0.000002190734,0.00006400274,0.0001305448,0.000006336216],"category_scores_gemma":[0.0005372575,0.00007503219,0.00001679498,0.0004606748,0.0002345889,0.0001032792,0.00002344141,0.000276302,9.066964e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000294961,"about_ca_system_score_gemma":0.00004887134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001412567,"about_ca_topic_score_gemma":0.0002761944,"domain_scores_codex":[0.9989333,0.00007223032,0.0002228292,0.0002585489,0.000388104,0.0001250071],"domain_scores_gemma":[0.999361,0.0001772444,0.0001853893,0.000139778,0.00009502532,0.00004154094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001489465,0.0001391896,0.002844515,0.00004860506,0.00000137582,0.000008353573,0.0008250606,0.0001187556,0.9939457,0.001360238,0.000002495732,0.0005567468],"study_design_scores_gemma":[0.001098842,0.0004483414,0.2551857,0.0001904911,0.000007168681,0.000005510076,0.00008490463,0.00008623376,0.7426366,0.0001941707,0.000006391976,0.00005562241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969303,0.00006492514,0.0007676482,0.001249317,0.00006290868,0.0001994366,0.000002667537,0.00001473504,0.0007080554],"genre_scores_gemma":[0.999477,0.00003110325,0.0002113125,0.0002161781,0.00003916367,0.000001111363,0.000002081317,0.00000575272,0.00001632222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2523412,"threshold_uncertainty_score":0.3059724,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2141917858","doi":"10.1172/jci15595","title":"Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":473,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Endocrinology; Internal medicine; Glucagon-like peptide-1; Catecholamine; Adrenal medulla; Receptor; Biology; Medicine; Type 2 diabetes; Diabetes mellitus","retraction":null,"screen_n_in":null,"score":{"opus":0.06906751738822468,"gpt":0.3158117500609002,"spread":0.2467442326726755,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000990062,0.0001356765,0.0003328515,0.0001088835,0.0001632701,0.0001056485,0.0001004394,0.00013587,0.00007513475],"category_scores_gemma":[0.002902019,0.0001183311,0.00009113662,0.0001240071,0.0003902066,0.0008517217,0.00004760498,0.0003223276,0.000009954952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006614183,"about_ca_system_score_gemma":0.00005383023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007413365,"about_ca_topic_score_gemma":0.000001290282,"domain_scores_codex":[0.997818,0.0005983334,0.0009289989,0.0002770427,0.0002431802,0.0001344648],"domain_scores_gemma":[0.9971102,0.001542096,0.0007999617,0.0001592367,0.00009390366,0.0002946347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002397519,0.0004358125,0.2138038,0.00007121656,0.00008315557,0.00001053582,0.00028366,0.002106697,0.7704567,0.00105126,0.007093719,0.004363681],"study_design_scores_gemma":[0.001295285,0.000481602,0.8878717,0.0001104808,0.0001865706,0.00006469504,0.00001133602,0.0115873,0.0882367,0.001798942,0.008198126,0.0001572482],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971495,0.000295023,0.00001494365,0.002030475,0.0002798779,0.0001369659,0.000004221938,0.00002521079,0.00006376434],"genre_scores_gemma":[0.9966352,0.0005037899,0.0009052848,0.00122017,0.0003669127,0.000001125703,0.000001375044,0.00001396606,0.0003521646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.68222,"threshold_uncertainty_score":0.4825401,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2043381283","doi":"10.1007/s40263-013-0076-8","title":"Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence","year":2013,"lang":"en","type":"review","venue":"CNS Drugs","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":469,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"RWTH Aachen University; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Alzheimer Society; National Institute on Aging; Eli Lilly and Company; Deutsche Forschungsgemeinschaft; National Institutes of Health; John Simon Guggenheim Memorial Foundation","keywords":"Insulin; Insulin resistance; Insulin receptor; Medicine; Neuroprotection; Neuroscience; Internal medicine; Endocrinology; Psychology","retraction":null,"screen_n_in":null,"score":{"opus":0.4543022185407687,"gpt":0.5255115660076726,"spread":0.07120934746690388,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001587204,0.000325994,0.001562611,0.0001641141,0.0001510413,0.00005825272,0.0004994847,0.0001729028,0.0001896005],"category_scores_gemma":[0.002790572,0.0002285758,0.0005934433,0.0004755729,0.0005877332,0.0001691064,0.0001660232,0.0002867477,0.0002514519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007629277,"about_ca_system_score_gemma":0.0009100367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000225605,"about_ca_topic_score_gemma":0.000001461063,"domain_scores_codex":[0.9961995,0.0009535452,0.001059193,0.0008782923,0.0005450952,0.0003643859],"domain_scores_gemma":[0.9933532,0.00484605,0.0004138665,0.000800106,0.0002154137,0.0003713907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002759311,0.0001956116,0.000005056838,0.03646408,0.00003808258,0.000005741764,0.0000206694,1.369554e-8,7.561357e-7,0.0009818241,0.003047333,0.9592133],"study_design_scores_gemma":[0.0002106986,0.0004444816,0.00002178199,0.1011273,0.0006533386,0.000005557814,0.000002591562,0.000008642165,0.00003190109,0.0003203959,0.896992,0.0001813395],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001283279,0.994141,0.000004152199,0.0007678678,0.0001372789,0.004346521,0.00009875707,0.00002426302,0.0003518195],"genre_scores_gemma":[0.000028064,0.9977043,0.000101513,0.0002027335,0.0002225495,0.0005736676,0.00002502702,0.00003752545,0.001104571],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9590319,"threshold_uncertainty_score":0.9321049,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4252795044","doi":"10.1172/jci0215595","title":"Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":430,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"National Institutes of Health","keywords":"Endocrinology; Internal medicine; Glucagon-like peptide-1; Adrenal medulla; Catecholamine; Receptor; Biology; Medicine; Diabetes mellitus; Type 2 diabetes","retraction":null,"screen_n_in":null,"score":{"opus":0.06906751738822468,"gpt":0.3158117500609002,"spread":0.2467442326726755,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000990062,0.0001356765,0.0003328515,0.0001088835,0.0001632701,0.0001056485,0.0001004394,0.00013587,0.00007513475],"category_scores_gemma":[0.002902019,0.0001183311,0.00009113662,0.0001240071,0.0003902066,0.0008517217,0.00004760498,0.0003223276,0.000009954952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006614183,"about_ca_system_score_gemma":0.00005383023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007413365,"about_ca_topic_score_gemma":0.000001290282,"domain_scores_codex":[0.997818,0.0005983334,0.0009289989,0.0002770427,0.0002431802,0.0001344648],"domain_scores_gemma":[0.9971102,0.001542096,0.0007999617,0.0001592367,0.00009390366,0.0002946347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002397519,0.0004358125,0.2138038,0.00007121656,0.00008315557,0.00001053582,0.00028366,0.002106697,0.7704567,0.00105126,0.007093719,0.004363681],"study_design_scores_gemma":[0.001295285,0.000481602,0.8878717,0.0001104808,0.0001865706,0.00006469504,0.00001133602,0.0115873,0.0882367,0.001798942,0.008198126,0.0001572482],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971495,0.000295023,0.00001494365,0.002030475,0.0002798779,0.0001369659,0.000004221938,0.00002521079,0.00006376434],"genre_scores_gemma":[0.9966352,0.0005037899,0.0009052848,0.00122017,0.0003669127,0.000001125703,0.000001375044,0.00001396606,0.0003521646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.68222,"threshold_uncertainty_score":0.4825401,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2062977162","doi":"10.1126/science.287.5450.125","title":"Modulation of Brain Reward Circuitry by Leptin","year":2000,"lang":"en","type":"article","venue":"Science","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":418,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Concordia University","funders":"","keywords":"Leptin; Brain stimulation reward; Stimulation; Hormone; Endocrinology; Internal medicine; Food intake; Brain stimulation; Neuroscience; Hypothalamus; Medicine; Central nervous system; Biology; Psychology; Obesity; Nucleus accumbens","retraction":null,"screen_n_in":null,"score":{"opus":0.01756237407964172,"gpt":0.2625871706358281,"spread":0.2450247965561864,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003639472,0.00005354272,0.00006701537,0.00006371277,0.0001678303,0.00003442334,0.0003371295,0.00002367369,0.0005577274],"category_scores_gemma":[0.0002230426,0.0000502527,0.00002455109,0.0007149853,0.0005330481,0.0004233152,0.00002316762,0.00004442944,0.0001404577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002075004,"about_ca_system_score_gemma":0.00005516062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009501222,"about_ca_topic_score_gemma":7.682845e-7,"domain_scores_codex":[0.9988822,0.00003093581,0.0001403724,0.000297865,0.0004725692,0.0001760419],"domain_scores_gemma":[0.999563,0.00005834266,0.0000533994,0.0002340319,0.00002905739,0.00006212253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003244136,0.00002004949,0.0007661841,0.000002282582,9.181727e-8,3.562295e-7,0.00009775804,0.0002912429,0.9764852,0.0007001791,0.0005613606,0.02107206],"study_design_scores_gemma":[0.0001105505,0.00003273397,0.06000128,0.000009022562,6.355651e-7,0.000003412659,0.000008200374,0.003096378,0.9229856,0.001314706,0.01235935,0.00007813956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802568,0.000007261052,0.000227573,0.0006440114,0.0000614774,0.00007074083,0.000004630042,0.00003234763,0.01869515],"genre_scores_gemma":[0.9955285,0.00000965556,0.000121549,0.0004621694,0.00001789221,0.000001055949,5.787438e-7,0.000003112787,0.003855445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05923509,"threshold_uncertainty_score":0.6106724,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2123857763","doi":"10.1152/ajpendo.2000.278.1.e1","title":"The adipoinsular axis: effects of leptin on pancreatic β-cells","year":2000,"lang":"en","type":"review","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":416,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Leptin; Endocrinology; Internal medicine; Hyperinsulinemia; Insulin; Adipose tissue; Hormone; Obesity; Diabetes mellitus; Secretion; Medicine; Biology; Insulin resistance","retraction":null,"screen_n_in":null,"score":{"opus":0.01457347203597788,"gpt":0.2765387068993166,"spread":0.2619652348633388,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002106732,0.0004280762,0.002635528,0.0002946804,0.0002430939,0.00001664026,0.0006727788,0.0001278509,0.00002484057],"category_scores_gemma":[0.0003250678,0.0002461336,0.0006147777,0.0003587575,0.00195452,0.00008113599,0.00008697537,0.0008842066,0.00003753778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001610777,"about_ca_system_score_gemma":0.0001535904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008480618,"about_ca_topic_score_gemma":3.273311e-7,"domain_scores_codex":[0.9961585,0.001774889,0.0009495461,0.0004037024,0.0002249665,0.0004883584],"domain_scores_gemma":[0.9943926,0.00294871,0.002002605,0.000466488,0.00006203266,0.0001275401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001275163,0.0001150286,7.582492e-7,0.00064425,0.0002127818,0.0000393745,0.00005254147,0.000004498903,0.01283283,0.002861851,0.0001496915,0.9829589],"study_design_scores_gemma":[0.00049184,0.0008518114,0.0006145124,0.001184029,0.0009361299,0.0004143629,0.00002089311,9.103047e-7,0.01088117,0.0007696201,0.983601,0.0002336569],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06786002,0.9307855,0.000003288356,0.00007812079,0.0007064565,0.0003125752,0.00001140953,0.00001357582,0.0002290261],"genre_scores_gemma":[0.01095173,0.9881546,0.00006480278,0.0002562753,0.000356657,0.00001316571,0.000001090393,0.00002966248,0.0001720186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9834514,"threshold_uncertainty_score":0.9999991,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1527986744","doi":"10.1038/35102112","title":"Partial leptin deficiency and human adiposity","year":2001,"lang":"en","type":"article","venue":"Nature","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":407,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital","funders":"","keywords":"Leptin; Endocrinology; Internal medicine; Appetite; Obesity; Hormone; Energy homeostasis; Adipocyte; Biology; Homeostasis; Adipose tissue; Human obesity; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01619013087329525,"gpt":0.279775935780475,"spread":0.2635858049071798,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006836646,0.00006398357,0.00006123982,0.00003085831,0.0002365524,0.00004016352,0.0001047536,0.0002937381,0.0001114691],"category_scores_gemma":[0.00006738578,0.0000554213,0.00002302001,0.0001392994,0.00006560736,0.000109507,0.00003908941,0.0005184919,0.00003741186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008251283,"about_ca_system_score_gemma":0.000007015696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007536373,"about_ca_topic_score_gemma":0.00001242303,"domain_scores_codex":[0.9993789,0.00003011943,0.00006952528,0.0002197026,0.0001645274,0.0001372373],"domain_scores_gemma":[0.9997479,0.00002735258,0.00002880827,0.0001280267,0.0000142915,0.00005362134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003770339,0.0001470952,0.08699175,0.00001315821,0.000001520248,0.00006177958,0.0001881227,0.00001735543,0.8189339,0.08539678,0.003934079,0.004276756],"study_design_scores_gemma":[0.0004158233,0.00008949523,0.4597049,0.00001177084,0.000009327568,0.00007151158,0.000009649789,0.0001326771,0.3899005,0.002310478,0.1471447,0.0001991315],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816308,0.0001289287,0.00002348266,0.0007333494,0.00009586163,0.00006277145,0.000001908765,0.00005280198,0.01727011],"genre_scores_gemma":[0.9974938,0.00002122234,0.00004514828,0.001076237,0.00009661641,9.785778e-7,0.000001146387,0.000004266046,0.001260584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4290334,"threshold_uncertainty_score":0.2265577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2346183877","doi":"10.1042/cs20160136","title":"Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity","year":2016,"lang":"en","type":"review","venue":"Clinical Science","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":404,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"","keywords":"Biology; Epigenetics; Obesity; Missing heritability problem; Genome-wide association study; Genetics; Bioinformatics; Candidate gene; Gene; Endocrinology; Single-nucleotide polymorphism; Genotype","retraction":null,"screen_n_in":null,"score":{"opus":0.1635801732574872,"gpt":0.4445205017109977,"spread":0.2809403284535105,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.002585095,0.0002226687,0.001012562,0.0001084311,0.0002415489,0.00004848684,0.001403739,0.0002186724,0.00002666799],"category_scores_gemma":[0.001079907,0.0001198035,0.0001904613,0.0006478481,0.006077308,0.00006492561,0.000728732,0.0002532804,0.00003207619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004707514,"about_ca_system_score_gemma":0.0003375767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001218303,"about_ca_topic_score_gemma":0.000003822108,"domain_scores_codex":[0.9965277,0.0007216228,0.001159951,0.0008793952,0.0003429647,0.0003683478],"domain_scores_gemma":[0.9971119,0.001174492,0.0007271507,0.0007541528,0.00008068811,0.0001516862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001954176,0.0001002337,0.0007463571,0.0002130057,0.00000203665,0.000002908401,0.0000146085,3.339061e-7,0.0001922592,0.0009125432,0.00001057305,0.9978032],"study_design_scores_gemma":[0.000221847,0.0003154405,0.01865005,0.001365819,0.00006918637,0.000005540031,0.000003358206,0.00003513572,0.0009998011,0.004476053,0.9735178,0.0003399211],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07718512,0.9214264,0.000006766289,0.0001210404,0.0003678978,0.0006598121,0.00002106816,0.00001149578,0.0002003791],"genre_scores_gemma":[0.002619743,0.9969611,0.000131575,0.0001063404,0.000103181,0.000009965438,0.000001016135,0.00001190261,0.00005514654],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9974633,"threshold_uncertainty_score":0.9966276,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2171857877","doi":"10.1053/j.gastro.2004.04.063","title":"Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure","year":2004,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":374,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Mount Sinai Hospital; Diabetes Canada; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Toronto General Hospital","funders":"","keywords":"Peptide YY; Endocrinology; Internal medicine; Energy homeostasis; Glucagon receptor; Receptor; Anorectic; Cholecystokinin; Ghrelin; Glucagon; Glucagon-like peptide-1; Agonist; Biology; Chemistry; Neuropeptide Y receptor; Neuropeptide; Food intake; Medicine; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.01183528104821466,"gpt":0.2142438873235569,"spread":0.2024086062753422,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005936229,0.000204304,0.0002441625,0.0001125968,0.0001355413,0.00005006053,0.0001596223,0.00009915269,0.00005939896],"category_scores_gemma":[0.00002265608,0.0001869713,0.00004711348,0.00005214897,0.0002707271,0.0001468678,0.0002099235,0.0001284911,0.0000062648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002015469,"about_ca_system_score_gemma":0.0000101321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003260899,"about_ca_topic_score_gemma":0.0003966412,"domain_scores_codex":[0.9986044,0.00009347396,0.0002324059,0.0005383224,0.0001494803,0.0003818812],"domain_scores_gemma":[0.9994429,0.00002761728,0.0001046409,0.0002508959,0.00001741782,0.0001565434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002242179,0.0008921714,0.07658481,0.00009631301,0.0001108802,0.0002641329,0.001304114,0.0006003758,0.8685133,0.03903657,0.0009795987,0.009375522],"study_design_scores_gemma":[0.007559785,0.003918005,0.8077739,0.00006401809,0.00005198748,0.001373074,0.00006821241,0.0003537391,0.1553833,0.01033068,0.01270182,0.0004213835],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955587,0.00004615278,0.001984288,0.001829502,0.0002795686,0.0000717232,0.00001236274,0.00006545665,0.0001522198],"genre_scores_gemma":[0.9971645,0.0001594504,0.0004089569,0.001764406,0.0001210648,0.000009900331,0.000009592057,0.00001826525,0.000343843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7311892,"threshold_uncertainty_score":0.7624468,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2024156402","doi":"10.1002/1096-9861(20000724)423:2<261::aid-cne6>3.0.co;2-6","title":"Chemical characterization of leptin-activated neurons in the rat brain","year":2000,"lang":"en","type":"article","venue":"The Journal of Comparative Neurology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":359,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Leptin; Nucleus; Hypothalamus; Endocrinology; Internal medicine; Biology; Arcuate nucleus; Arc (geometry); Solitary tract; Galanin; Parabrachial Nucleus; In situ hybridization; Neuropeptide; Lateral parabrachial nucleus; Area postrema; Central nervous system; Leptin receptor; Neuroscience; Messenger RNA; Medicine; Receptor; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03941402901242166,"gpt":0.2928108615996823,"spread":0.2533968325872606,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040014,0.00009110769,0.0002320355,0.00006965009,0.000061507,0.00001145602,0.0004477117,0.00003980017,0.0001807734],"category_scores_gemma":[0.00008507448,0.00005077067,0.00005470479,0.0003119881,0.000261685,0.0001512455,0.0000198389,0.0003864701,0.00001432501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004753645,"about_ca_system_score_gemma":0.0000278551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001659145,"about_ca_topic_score_gemma":0.000001557256,"domain_scores_codex":[0.9977708,0.001398237,0.0003911823,0.00009116014,0.0002171174,0.0001314329],"domain_scores_gemma":[0.9984062,0.001024404,0.0003384305,0.0001589728,0.00004733124,0.00002460071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008283446,0.0001020862,0.0003766653,0.000001323781,0.000001966851,0.000009033348,0.001292105,0.000467048,0.9962105,0.0002981192,0.0002002692,0.000212589],"study_design_scores_gemma":[0.0005067319,0.0004282936,0.09216949,0.000005388899,0.000007834402,0.000304906,0.00002177881,0.0005059119,0.8982692,0.0002985481,0.007433681,0.00004821257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885108,0.000005072207,0.00004299866,0.01033268,0.00008555812,0.0001262061,0.000001668402,0.000004082302,0.0008909688],"genre_scores_gemma":[0.9962168,0.00003472036,0.00000377558,0.003600545,0.00006888202,8.464178e-7,7.307019e-7,0.000004464967,0.00006923049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09794122,"threshold_uncertainty_score":0.2070368,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2112947586","doi":"10.1210/jc.2003-031964","title":"Non-Acylated Ghrelin Counteracts the Metabolic But Not the Neuroendocrine Response to Acylated Ghrelin in Humans","year":2004,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":354,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Theratechnologies (Canada)","funders":"","keywords":"Endocrinology; Ghrelin; Internal medicine; Secretagogue; Chemistry; Stimulation; Receptor; Prolactin; Endocrine system; Enteroendocrine cell; Hormone; Biology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.05571986870809981,"gpt":0.3693617831619505,"spread":0.3136419144538506,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.005012198,0.000442879,0.001247061,0.0003550788,0.0005475702,0.0001107369,0.002707253,0.0001231007,0.0001238723],"category_scores_gemma":[0.009471626,0.0002153683,0.0005561636,0.001067017,0.0009790274,0.0003705703,0.000466685,0.002778808,0.0003988424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003735612,"about_ca_system_score_gemma":0.0004129131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001960009,"about_ca_topic_score_gemma":0.0001034687,"domain_scores_codex":[0.9906475,0.003961644,0.002950168,0.000513163,0.0009510923,0.000976447],"domain_scores_gemma":[0.990254,0.006477809,0.001384092,0.001254674,0.0003442583,0.0002851466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.05460267,0.002965997,0.004117485,0.00002031355,0.0005163598,0.003732934,0.005675233,0.07345182,0.8147455,0.01766365,0.004284642,0.01822334],"study_design_scores_gemma":[0.007063096,0.0005291973,0.5922249,0.00005877475,0.0002983994,0.001415146,0.0002194036,0.0002097896,0.1784335,0.002397631,0.2168216,0.0003284703],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9029152,0.0007146195,0.00009407578,0.09345633,0.002035446,0.0006109808,0.00001073005,0.00003928703,0.0001233615],"genre_scores_gemma":[0.9686297,0.004954687,0.00009517016,0.02482576,0.0009484143,0.0000118764,7.422953e-7,0.00004713961,0.0004865262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.636312,"threshold_uncertainty_score":0.9995219,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2170821866","doi":"10.1186/1297-9686-34-1-105","title":"Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels","year":2002,"lang":"en","type":"article","venue":"Genetics Selection Evolution","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":343,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Ministry of Agriculture - Saskatchewan","keywords":"Biology; Allele; Leptin; Genotype; Genetics; Allele frequency; Missense mutation; Exon; Population; Gene; Endocrinology; Mutation; Obesity","retraction":null,"screen_n_in":null,"score":{"opus":0.04465582315722953,"gpt":0.2360903615675867,"spread":0.1914345384103572,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003467857,0.000114401,0.0001467571,0.0001452552,0.0001490079,0.0000373685,0.00006929172,0.00008672363,0.00003090137],"category_scores_gemma":[0.0001999308,0.00009119827,0.00003318864,0.0005147004,0.00005279572,0.0001200024,0.00001209066,0.0001214973,0.000008534255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001990574,"about_ca_system_score_gemma":0.00001709296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009406935,"about_ca_topic_score_gemma":0.0003833044,"domain_scores_codex":[0.998547,0.0002930041,0.0002963055,0.0002549303,0.0004211685,0.0001876093],"domain_scores_gemma":[0.9992744,0.0001359579,0.0002858716,0.0001161354,0.0001560796,0.00003159111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00009545141,0.0001372925,0.04770949,0.00001865283,0.000009695028,0.000003698148,0.001129186,0.003507799,0.9451605,0.0003339731,0.0003763568,0.001517906],"study_design_scores_gemma":[0.001519253,0.0005104247,0.5064611,0.00002381076,0.00004175307,0.0001090012,0.0002271899,0.0528633,0.4373781,0.000290259,0.0003994595,0.0001763246],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940102,0.0001328762,0.004319269,0.0007545839,0.00006711873,0.0003752173,0.000007982999,0.00002518766,0.0003076158],"genre_scores_gemma":[0.9983531,0.0001003674,0.0005211145,0.00009223278,0.00006830542,0.0000139954,0.000003800177,0.000009689862,0.0008373607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5077824,"threshold_uncertainty_score":0.3718958,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2557610606","doi":"10.3389/fnins.2016.00540","title":"The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge","year":2016,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":337,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fish <Actinopterygii>; Biology; Endocrine system; Vertebrate; Hormone; Fish Proteins; Physiology; Fish physiology; Zoology; Endocrinology; Fishery","retraction":null,"screen_n_in":null,"score":{"opus":0.06662276355238071,"gpt":0.3421512367504377,"spread":0.275528473198057,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007096657,0.0003377952,0.00127098,0.0005028378,0.00009115522,0.00002474942,0.001474415,0.00005467744,0.00000632577],"category_scores_gemma":[0.002768032,0.0002147759,0.0003122629,0.002376517,0.0007324907,0.0002500982,0.0003117548,0.0003806452,0.000004331512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001046272,"about_ca_system_score_gemma":0.0003372218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001016058,"about_ca_topic_score_gemma":0.000009015415,"domain_scores_codex":[0.9958934,0.0008424898,0.001458464,0.0008064841,0.0005727094,0.000426476],"domain_scores_gemma":[0.9973908,0.0005268012,0.001101817,0.0008436022,0.00006355542,0.00007340834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007761366,0.0001216587,0.00007982153,0.02493592,8.114297e-7,0.000004068247,0.00001413723,0.000001411088,0.0001619395,0.001400701,0.002897864,0.9703739],"study_design_scores_gemma":[0.0001497486,0.00009392865,0.0004646989,0.06591952,0.00001877832,0.00001633443,0.000001057532,0.00005654968,0.0008058287,0.0003369285,0.9319589,0.0001777336],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008480381,0.9949428,0.0001883644,0.000133061,0.002836243,0.001198716,0.00005458715,0.00001577694,0.0005456731],"genre_scores_gemma":[0.0003402593,0.9992177,0.00002908345,0.00008810838,0.0000404467,0.00006054463,0.000002174295,0.00002387741,0.0001978173],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9701962,"threshold_uncertainty_score":0.8758307,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144392815","doi":"10.1093/hmg/10.14.1465","title":"Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus","year":2001,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":330,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Medical Research Council","keywords":"Endocrinology; Internal medicine; Hypothalamus; Biology; Hyperinsulinemia; Leptin; Obesity; Haploinsufficiency; Appetite; Melanocortin 4 receptor; Melanocortin; Medicine; Hormone; Insulin resistance; Gene; Phenotype; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.02146270502291036,"gpt":0.2408815310206081,"spread":0.2194188259976977,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009887848,0.0001158686,0.0001355597,0.00003984015,0.0002436317,0.00001982182,0.0003477863,0.00006174385,0.00001971232],"category_scores_gemma":[0.00008923162,0.00007873423,0.0001138062,0.000340035,0.0004339591,0.00003001848,0.0001727471,0.00009471786,0.000002226643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001487396,"about_ca_system_score_gemma":0.00002960776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002005755,"about_ca_topic_score_gemma":0.000004435267,"domain_scores_codex":[0.9987898,0.0001568768,0.0002499091,0.0002471834,0.0003980153,0.0001581727],"domain_scores_gemma":[0.9991164,0.00002295597,0.0002063332,0.0005507386,0.00006464378,0.0000389559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003740467,0.0001475031,0.01185461,0.00001418527,0.000004411886,0.000005445709,0.0001500516,0.001491014,0.9836754,0.002411266,0.00001737261,0.0002249999],"study_design_scores_gemma":[0.0001601135,0.00004486712,0.2957102,0.00001635394,0.0000272783,0.000046437,0.00002445253,0.0002142565,0.7019278,0.001196869,0.000562562,0.00006882093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983558,0.0003142828,0.0001304512,0.0001018705,0.0001138876,0.0002697746,0.000005179806,0.00001209741,0.0006966678],"genre_scores_gemma":[0.9994703,0.0001568521,0.00009252589,0.00008454309,0.00002246783,0.000001797565,3.666402e-7,0.00001252563,0.0001586016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2838556,"threshold_uncertainty_score":0.3210689,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2025378252","doi":"10.1016/j.neurobiolaging.2005.08.017","title":"High-fat diets, insulin resistance and declining cognitive function","year":2005,"lang":"en","type":"review","venue":"Neurobiology of Aging","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":329,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Trent University; Baycrest Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Insulin resistance; Endocrinology; Ingestion; Insulin; Type 2 diabetes; Internal medicine; Diabetes mellitus; Cognition; Medicine; Psychology; Biology; Neuroscience","retraction":null,"screen_n_in":null,"score":{"opus":0.05622008878719609,"gpt":0.3202875868970871,"spread":0.2640674981098911,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001816234,0.0002955402,0.0009634036,0.0002035749,0.0001614607,0.0000208318,0.0001798573,0.000249695,0.000044801],"category_scores_gemma":[0.0002972524,0.0002614344,0.0001521871,0.0002461819,0.0003347481,0.0001162784,0.0001341353,0.0004065997,0.0000514849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001606992,"about_ca_system_score_gemma":0.00004423054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002732872,"about_ca_topic_score_gemma":0.000007553023,"domain_scores_codex":[0.9979689,0.0004282623,0.0005565815,0.0006998417,0.00009770349,0.0002486737],"domain_scores_gemma":[0.997809,0.001282395,0.0006042534,0.0002079756,0.00004261707,0.00005376589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005500225,0.00005446357,0.00007231198,0.002735923,0.00003474598,0.00001367024,0.00005735329,0.000004063817,0.0002719434,0.00122412,0.0002393023,0.9952371],"study_design_scores_gemma":[0.0004462296,0.0001567087,0.0009697531,0.006349971,0.0004075841,0.00002895161,0.000008063079,0.000002569586,0.001420941,0.0002066435,0.9896195,0.0003830721],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00979861,0.9882976,0.00004881984,0.00008561077,0.000508496,0.0003533257,0.00004577069,0.0000734737,0.0007883173],"genre_scores_gemma":[0.009278411,0.9893687,0.0001334491,0.0003200273,0.000249761,0.00001158718,0.00003072235,0.0000306004,0.0005767732],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.994854,"threshold_uncertainty_score":0.9999838,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2095461204","doi":"10.1016/s0304-3940(02)00241-0","title":"Peripheral ghrelin selectively increases Fos expression in neuropeptide Y – synthesizing neurons in mouse hypothalamic arcuate nucleus","year":2002,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":324,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Orexigenic; Ghrelin; Internal medicine; Endocrinology; Arcuate nucleus; Arc (geometry); Neuropeptide Y receptor; Growth hormone secretagogue receptor; Hypothalamus; Neuropeptide; Biology; Receptor; Chemistry; Hormone; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03370464390478367,"gpt":0.2355017254117095,"spread":0.2017970815069259,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002447224,0.0003238117,0.0002939634,0.0005059738,0.0002867089,0.0002153414,0.0007206961,0.00006554779,0.00005656703],"category_scores_gemma":[0.001364746,0.0003228476,0.00009150008,0.001227576,0.0003861604,0.001017623,0.0001922548,0.0005225224,0.00006963231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001183314,"about_ca_system_score_gemma":0.00002186684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000900722,"about_ca_topic_score_gemma":0.00004664803,"domain_scores_codex":[0.9962875,0.0006038834,0.0004759498,0.001188624,0.0006225117,0.0008215224],"domain_scores_gemma":[0.9988214,0.0003752036,0.0001681455,0.000458205,0.00001550413,0.0001614989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002710418,0.0002158578,0.01900707,0.00000788699,1.239597e-7,0.0003227537,0.0002125968,0.005726713,0.9735775,0.00002742701,0.0002009396,0.0006740246],"study_design_scores_gemma":[0.0006253111,0.00009875475,0.1957124,0.00006756534,0.000002070756,0.00007941326,0.00002005164,0.03429265,0.7675112,0.00002658761,0.001169293,0.0003947141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961598,0.000009632871,0.0001129833,0.002472761,0.0002098514,0.0003724197,0.00001084798,0.0001551258,0.0004966109],"genre_scores_gemma":[0.9849399,0.00008778581,0.0001900713,0.0144056,0.0000545564,0.00002682009,3.688929e-7,0.00004636071,0.0002485414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2060663,"threshold_uncertainty_score":0.9999223,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2156796753","doi":"10.1172/jci43134","title":"Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":313,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; University of Aberdeen; McGill University","keywords":"Arcuate nucleus; Leptin; Neurogenesis; Hypothalamus; Endocrinology; Biology; Internal medicine; Nucleus; Protein turnover; Neuroscience; Medicine; Obesity; Protein biosynthesis","retraction":null,"screen_n_in":null,"score":{"opus":0.1838916083516747,"gpt":0.3358793078396632,"spread":0.1519876994879885,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001316419,0.00008517012,0.0002789351,0.00009882771,0.00004655345,0.00001464943,0.0003426342,0.0001168383,0.00002767537],"category_scores_gemma":[0.00248856,0.00006047964,0.0001832261,0.0004078603,0.0002747625,0.0003405402,0.00004781778,0.0003496961,0.000005391912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002085814,"about_ca_system_score_gemma":0.0001431739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003674853,"about_ca_topic_score_gemma":0.00001133878,"domain_scores_codex":[0.9974638,0.0003821566,0.001457612,0.000164978,0.000410163,0.0001213309],"domain_scores_gemma":[0.9977238,0.0003670664,0.001407982,0.0002075133,0.0001857966,0.0001078323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002732116,0.0004143454,0.3779131,0.00004892877,0.00001441109,0.00001864363,0.002448679,0.0008362499,0.597681,0.01232291,0.0006566902,0.00737179],"study_design_scores_gemma":[0.0007775933,0.0001223341,0.2755816,0.0003462752,0.00001576361,0.00001824633,0.00002758253,0.009360842,0.6459453,0.06728811,0.0004259077,0.00009050455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971991,0.00002522593,0.0003697379,0.0008705071,0.0003383589,0.00005329381,0.000001881884,0.000005836216,0.001136022],"genre_scores_gemma":[0.9962705,0.0001342849,0.0008316481,0.002525272,0.0001318859,3.971233e-7,2.050039e-7,0.000008176718,0.00009765867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1023315,"threshold_uncertainty_score":0.2979218,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2971451438","doi":"10.1016/j.cmet.2019.08.005","title":"Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy","year":2019,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":309,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Fonds de Recherche du Québec - Santé; National Institutes of Health; University of Texas Southwestern Medical Center; Canadian Institutes of Health Research; Welch Foundation","keywords":"Weight loss; Leptin; Sensitization; Insulin; Medicine; Reduction (mathematics); Endocrinology; Internal medicine; Diabetes mellitus; Obesity; Immunology; Mathematics","retraction":null,"screen_n_in":null,"score":{"opus":0.01319144926524907,"gpt":0.2399090344219824,"spread":0.2267175851567333,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000125272,0.0001144931,0.0001384528,0.0000670228,0.0001068232,0.00008158368,0.00007652795,0.00008367316,0.0003210849],"category_scores_gemma":[0.00002634691,0.0001086025,0.00002786882,0.000165408,0.00006840465,0.0004810622,0.00002919087,0.00009670736,0.0005113867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007255981,"about_ca_system_score_gemma":0.00002920523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002428696,"about_ca_topic_score_gemma":0.000001010497,"domain_scores_codex":[0.9989455,0.0001467657,0.0001639536,0.0003853407,0.0001894423,0.0001690358],"domain_scores_gemma":[0.9995229,0.00002527972,0.00008957271,0.0002255754,0.00003715967,0.00009952681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004194899,0.00006015614,0.0003561652,0.00001184274,0.000001063889,0.000003715397,0.0002305399,0.0003696925,0.982698,0.01305079,0.00005296626,0.003123133],"study_design_scores_gemma":[0.0005519644,0.00004792462,0.01754541,0.000004494718,0.0000123197,0.00002754115,0.00003683318,0.002136321,0.9570854,0.002726814,0.01966985,0.0001551338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928511,0.0001034084,0.00007742673,0.0002326488,0.0005558721,0.0001868652,0.0000032856,0.00005242059,0.005936991],"genre_scores_gemma":[0.9959094,0.0002908274,0.0001281251,0.0001349496,0.0003901426,0.000002234603,0.000009885754,0.00001441559,0.003120011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0256126,"threshold_uncertainty_score":0.6573012,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1983901940","doi":"10.1210/en.2005-0473","title":"Peripheral Exendin-4 and Peptide YY3–36 Synergistically Reduce Food Intake through Different Mechanisms in Mice","year":2005,"lang":"en","type":"article","venue":"Endocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":309,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Diabetes Canada; University of Toronto","funders":"University of Toronto; University of Cincinnati","keywords":"Peptide YY; Internal medicine; Endocrinology; Agonist; Antagonist; Chemistry; Receptor; Ingestion; Taste; Glucagon-like peptide-1; Receptor antagonist; Gastric emptying; Neuropeptide Y receptor; Medicine; Neuropeptide; Stomach","retraction":null,"screen_n_in":null,"score":{"opus":0.02930411401455717,"gpt":0.2721597883181906,"spread":0.2428556743036334,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000391373,0.0001928256,0.0002545732,0.00008474362,0.0001109015,0.00003565361,0.0002281916,0.00007866512,0.0002676786],"category_scores_gemma":[0.0001563527,0.0001764869,0.00004505783,0.0001124059,0.0002044943,0.0001709474,0.000161329,0.0002456232,0.00005889386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007354125,"about_ca_system_score_gemma":0.00001945998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002507693,"about_ca_topic_score_gemma":0.0002141169,"domain_scores_codex":[0.9983825,0.0001340331,0.000285481,0.0005308486,0.0001613788,0.0005057249],"domain_scores_gemma":[0.9994548,0.0001650644,0.00006720934,0.0002199665,0.00001502313,0.00007795225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001183391,0.0002109808,0.0005893454,0.00001510521,0.000006933973,0.00008314045,0.0005838713,0.00009437469,0.5494624,0.4431879,0.0002521591,0.005395402],"study_design_scores_gemma":[0.00143458,0.0004976409,0.05324378,0.00002408877,0.00001232217,0.0003633767,0.0001452349,0.0006270203,0.8977907,0.02214186,0.02334811,0.0003712375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881393,0.00007719747,0.001479109,0.003024805,0.0002395838,0.0001753161,0.000007468866,0.00008455401,0.006772717],"genre_scores_gemma":[0.9953163,0.0001951074,0.00220173,0.001032899,0.0001256205,0.00002153912,0.000002527828,0.00001725318,0.001087082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.421046,"threshold_uncertainty_score":0.7196928,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2731104443","doi":"10.1016/j.molmet.2017.06.015","title":"Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency","year":2017,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":300,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Fondation pour la Recherche Médicale; National Institute of Diabetes and Digestive and Kidney Diseases; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institute for Health and Care Research; NIHR Cambridge Biomedical Research Centre; Wellcome Trust; Medical Research Council; Wellcome; Assistance publique-Hôpitaux de Paris; Agence Nationale de la Recherche; National Science Foundation","keywords":"Melanocortin 4 receptor; Melanocortin; Agonist; Endocrinology; Melanocortin 3 receptor; Receptor; Chemistry; Internal medicine; G protein-coupled receptor; Medicine; Melanocortin receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.04290079788074629,"gpt":0.3140348440028317,"spread":0.2711340461220854,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001634569,0.0001710226,0.0002984706,0.0001706816,0.0002628758,0.0001114559,0.0006186777,0.00007777921,0.000211586],"category_scores_gemma":[0.002520675,0.0001643172,0.0001283686,0.0002022207,0.0002070534,0.0002649762,0.0001439654,0.0001383987,0.0001090129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000417659,"about_ca_system_score_gemma":0.0001551109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001526055,"about_ca_topic_score_gemma":0.00004182912,"domain_scores_codex":[0.9971622,0.0004391628,0.0004273789,0.000467653,0.001214196,0.0002894439],"domain_scores_gemma":[0.9982895,0.00004155595,0.0004490105,0.0009340461,0.0002102313,0.00007564723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001899417,0.0001264272,0.001514487,0.00001129746,0.000004115549,0.00001028292,0.0001620488,0.0003305644,0.9700314,0.01373712,0.00005198325,0.01400124],"study_design_scores_gemma":[0.0009294878,0.00001835543,0.1342748,0.00002333799,0.00006039481,0.000003444814,0.00001327652,0.001248089,0.8556564,0.00399318,0.003609118,0.0001700801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803053,0.0004828379,0.0002970138,0.0003865264,0.0004046757,0.0004523071,0.00001441091,0.00002429911,0.0176327],"genre_scores_gemma":[0.9990454,0.00005779177,0.000486504,0.0001430192,0.00004488934,0.00003042385,0.000004958012,0.0000191186,0.0001678394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1327603,"threshold_uncertainty_score":0.670066,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2024138018","doi":"10.1038/nature06852","title":"Upper intestinal lipids trigger a gut–brain–liver axis to regulate glucose production","year":2008,"lang":"en","type":"article","venue":"Nature","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":294,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University of Alberta; Toronto General Hospital; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Small intestine; Endogeny; Glucose homeostasis; Internal medicine; Homeostasis; Endocrinology; Biology; Blood sugar; Nutrient sensing; Digestion (alchemy); Biochemistry; Diabetes mellitus; Chemistry; Medicine; Signal transduction; Insulin resistance","retraction":null,"screen_n_in":null,"score":{"opus":0.01895023975721056,"gpt":0.2598931690434289,"spread":0.2409429292862184,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001581564,0.0001703853,0.0001538492,0.0001643297,0.0002861176,0.00003276239,0.0002483712,0.0004435542,0.0002514212],"category_scores_gemma":[0.001496545,0.0001457747,0.00009036851,0.0006614439,0.0001099175,0.0002906801,0.00008055018,0.0009575476,0.0004613491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005853672,"about_ca_system_score_gemma":0.00004957535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006032909,"about_ca_topic_score_gemma":0.000003755585,"domain_scores_codex":[0.9984249,0.00008476631,0.0001783402,0.0005800861,0.0004562785,0.0002755563],"domain_scores_gemma":[0.9991815,0.00008689241,0.00006686257,0.000406636,0.0001232684,0.0001348478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002598833,0.0001726176,0.002006617,0.00002417343,0.000004453765,0.0000851453,0.0006657403,0.0001677028,0.7677852,0.00144571,0.2212525,0.006130261],"study_design_scores_gemma":[0.0002320212,0.00009516427,0.06303089,0.00003335127,0.000004100798,0.000317909,0.000006331068,0.0001101965,0.5579825,0.000206443,0.3777921,0.0001889223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808432,0.0001285484,0.00008722199,0.01509577,0.0007697757,0.000329863,0.000004679108,0.0001628789,0.002578077],"genre_scores_gemma":[0.9678686,0.00005232625,0.001107505,0.006094156,0.0007486336,0.00001142105,0.000004299791,0.00002199718,0.02409104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2098027,"threshold_uncertainty_score":0.5944518,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2037039366","doi":"10.1016/j.cbpb.2011.07.006","title":"Glucosensing and glucose homeostasis: From fish to mammals","year":2011,"lang":"en","type":"review","venue":"Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":293,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Victoria","funders":"","keywords":"Glucose homeostasis; Homeostasis; Fish <Actinopterygii>; Energy homeostasis; Biology; Endocrinology; Diabetes mellitus; Fishery; Obesity; Insulin resistance","retraction":null,"screen_n_in":null,"score":{"opus":0.0635238265097309,"gpt":0.3333202922190002,"spread":0.2697964657092693,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001181979,0.0007951296,0.001718796,0.00006499016,0.0002783518,0.00005825297,0.0003191091,0.0009213858,0.00005548177],"category_scores_gemma":[0.0001622812,0.0007084861,0.0001917216,0.0001921881,0.001150411,0.00004115048,0.0005741426,0.0004565538,0.00001794629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002586495,"about_ca_system_score_gemma":0.00009568351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008671048,"about_ca_topic_score_gemma":6.590627e-7,"domain_scores_codex":[0.9967153,0.0003422996,0.0005717085,0.001794563,0.00007431603,0.000501781],"domain_scores_gemma":[0.9982128,0.0003537118,0.0003801139,0.0005903102,0.00005768338,0.0004053997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008839802,0.00006833636,0.000004074876,0.001309143,0.000120281,0.00001900838,0.00008004279,9.278452e-8,0.9485072,0.0001976895,0.0004120636,0.04919363],"study_design_scores_gemma":[0.0002014569,0.00008042122,0.00001285612,0.0006752926,0.0001537907,0.00007504205,0.0000227467,0.000002162382,0.6595635,0.0004335736,0.3382402,0.0005390172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.368999,0.6297094,0.00002565341,0.00005041551,0.00009216891,0.0002874355,0.0004968666,0.00003804429,0.0003009653],"genre_scores_gemma":[0.1012955,0.8966792,0.0002193359,0.0006331055,0.0002789621,0.00006174133,0.0006886804,0.00003139773,0.0001120154],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3378281,"threshold_uncertainty_score":0.9995366,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2015037392","doi":"10.1523/jneurosci.3890-09.2009","title":"Ghrelin Promotes and Protects Nigrostriatal Dopamine Function via a UCP2-Dependent Mitochondrial Mechanism","year":2009,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":291,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Carleton University","funders":"National Health and Medical Research Council; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; Medical Research Council; Michael J. Fox Foundation for Parkinson's Research","keywords":"Ghrelin; Substantia nigra; Dopamine; Endocrinology; Pars compacta; Internal medicine; Growth hormone secretagogue receptor; MPTP; Biology; Neurodegeneration; Tyrosine hydroxylase; Chemistry; Dopaminergic; Hormone; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02059956253117653,"gpt":0.2461172490755692,"spread":0.2255176865443926,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003540235,0.0001604363,0.0002143064,0.0002262612,0.0002626824,0.0001902032,0.0003340795,0.0000641913,0.000009696448],"category_scores_gemma":[0.0008649694,0.0001273036,0.00008001221,0.0004146555,0.0001188469,0.0008592506,0.00005826281,0.0003009173,0.000007104775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002742363,"about_ca_system_score_gemma":0.00007262692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002086553,"about_ca_topic_score_gemma":9.929197e-7,"domain_scores_codex":[0.9979666,0.0001286093,0.0004414868,0.0003717458,0.0008232145,0.0002682914],"domain_scores_gemma":[0.9989813,0.00007546761,0.0004712218,0.0001785403,0.00009765953,0.0001958179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001753346,0.0001200259,0.00002384129,0.000004520999,4.357893e-7,0.00007909223,0.00003734237,0.00003913881,0.9948419,0.0005602904,0.00003074242,0.004087321],"study_design_scores_gemma":[0.001090591,0.003066475,0.01503084,0.00004106663,0.0000134184,0.001401321,0.000008902231,0.002274962,0.9682471,0.007897974,0.0007518283,0.0001755542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789438,0.00003146827,0.01790183,0.001380215,0.00128405,0.0003337252,0.000002877348,0.00003085821,0.00009119679],"genre_scores_gemma":[0.997987,0.00005171186,0.0005430951,0.000856766,0.0003518057,0.000001562484,1.188036e-7,0.000007651705,0.0002003403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02659485,"threshold_uncertainty_score":0.519129,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2080867987","doi":"10.1523/jneurosci.2584-06.2007","title":"Serotonin Activates the Hypothalamic-Pituitary-Adrenal Axis via Serotonin 2C Receptor Stimulation","year":2007,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":288,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging; Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression; National Institutes of Health; National Institute of Mental Health; Medical Research Council; Giannini Foundation of Agricultural Economics; Wellcome Trust; Ellison Medical Foundation","keywords":"Endocrinology; Internal medicine; Serotonin; Hypothalamus; Agonist; 5-HT receptor; Receptor; Corticotropin-releasing hormone; Stimulation; In situ hybridization; Downregulation and upregulation; Chemistry; Corticosterone; Biology; Hormone; Gene expression; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03130247747209652,"gpt":0.2809862103230612,"spread":0.2496837328509647,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001497564,0.0002106586,0.0002365874,0.0002456139,0.0005537929,0.0001727743,0.0009628937,0.0000773526,0.00007059977],"category_scores_gemma":[0.001087266,0.000141078,0.0001656263,0.0009341243,0.0004144577,0.001164328,0.0001174115,0.0004992469,0.00003796863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008578656,"about_ca_system_score_gemma":0.0001042534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007492264,"about_ca_topic_score_gemma":0.000003382744,"domain_scores_codex":[0.9971114,0.0002086236,0.0006773168,0.0003774236,0.001158584,0.0004666575],"domain_scores_gemma":[0.9978538,0.0006794672,0.0007449577,0.0003418565,0.0001758185,0.0002040788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001160826,0.0001023087,0.004577235,0.000005001802,0.000001149363,0.00004278303,0.0001708806,0.002115145,0.9893649,0.0002237226,0.0001892304,0.003091561],"study_design_scores_gemma":[0.0003384257,0.000321041,0.2116114,0.00002815047,0.000006823468,0.0003909315,0.00002921623,0.002957473,0.7771105,0.0004490141,0.006617865,0.0001392154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884592,0.00002102125,0.007986224,0.001658052,0.001087985,0.0003192404,0.000003474477,0.00003225944,0.0004325875],"genre_scores_gemma":[0.9970904,0.0000502911,0.0006637189,0.001500808,0.0002886463,0.000002040772,2.673151e-7,0.00001782383,0.0003859919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2122544,"threshold_uncertainty_score":0.5752994,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1986199235","doi":"10.1210/jc.2004-1251","title":"Ghrelin, Peptide YY, Glucose-Dependent Insulinotropic Polypeptide, and Hunger Responses to a Mixed Meal in Anorexic, Obese, and Control Female Adolescents","year":2005,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":280,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Children's Hospital; LMC Diabetes & Endocrinology (Canada)","funders":"University of British Columbia","keywords":"Ghrelin; Peptide YY; Meal; Endocrinology; Internal medicine; Medicine; Appetite; Obesity; Hormone; Neuropeptide Y receptor; Neuropeptide; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.04273820261589793,"gpt":0.3424868920982285,"spread":0.2997486894823305,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001716094,0.0002444959,0.000907221,0.0002897844,0.0001497728,0.00004543648,0.0005119647,0.0001468705,0.00002823346],"category_scores_gemma":[0.003372636,0.0001664536,0.0001576606,0.0002056789,0.0004981108,0.0002733466,0.0002224111,0.0009222231,0.00004631271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002082108,"about_ca_system_score_gemma":0.0001089688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004467154,"about_ca_topic_score_gemma":0.000145873,"domain_scores_codex":[0.9951623,0.001874386,0.001607649,0.0003694785,0.0004667856,0.0005193785],"domain_scores_gemma":[0.9968969,0.001710433,0.0006106854,0.0003493461,0.0001409516,0.0002916851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02230218,0.001739845,0.6606401,0.00005041861,0.0001623979,0.0006823251,0.001329017,0.0004612464,0.1539444,0.002747116,0.001018994,0.1549219],"study_design_scores_gemma":[0.005824888,0.0003121532,0.9593982,0.00006197456,0.00009622935,0.0004642949,0.00006957356,0.00008304192,0.01957442,0.0003820873,0.01357516,0.0001580338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852312,0.00321626,0.0001502987,0.01049917,0.0004854741,0.0003093064,0.000007107162,0.00001871932,0.00008252173],"genre_scores_gemma":[0.9850857,0.006441949,0.000555218,0.006800595,0.000790964,0.000003675638,1.384807e-7,0.00002036665,0.0003014455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.298758,"threshold_uncertainty_score":0.6787781,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049454720","doi":"10.1073/pnas.1834402100","title":"Hypothalamic malonyl-CoA as a mediator of feeding behavior","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":279,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Nutrasource","funders":"","keywords":"Orexigenic; Malonyl-CoA; Internal medicine; Endocrinology; Neuropeptide Y receptor; Proopiomelanocortin; Fatty acid synthase; Acetyl-CoA carboxylase; Hypothalamus; Chemistry; Neuropeptide; Biology; Pyruvate carboxylase; Enzyme; Biochemistry; Metabolism; Medicine; Beta oxidation; Lipid metabolism; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.05400702607584989,"gpt":0.3103480020519291,"spread":0.2563409759760792,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001095381,0.00009667705,0.0001690373,0.0002039499,0.0001896786,0.00002032275,0.0007735724,0.00007879917,0.00006237719],"category_scores_gemma":[0.002273238,0.00006839922,0.0000969383,0.0009669014,0.001053118,0.0005201285,0.00008856993,0.0001257219,0.000004731176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002404945,"about_ca_system_score_gemma":0.0000542067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002839266,"about_ca_topic_score_gemma":2.385517e-8,"domain_scores_codex":[0.997609,0.00001217992,0.0003827544,0.000276461,0.00155478,0.0001648326],"domain_scores_gemma":[0.998954,0.0002115816,0.0005864627,0.0000107654,0.0001943439,0.00004284165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004796691,0.00005243921,0.01340208,0.0000238313,0.000001431512,7.980383e-9,0.0000800961,0.00001301402,0.8490905,0.1371738,0.00009584837,0.00006222046],"study_design_scores_gemma":[0.0001347857,0.00003910685,0.07052662,0.00004341818,0.000009079117,0.00001567846,0.0000810565,0.00007503046,0.9028757,0.02591513,0.0002201833,0.00006419244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780863,0.00003318894,3.26136e-7,0.0007091401,0.00003691429,0.0001807953,0.000008542512,0.00001077433,0.02093405],"genre_scores_gemma":[0.9987635,0.00003114755,0.0006685792,0.0001863075,0.00003346303,0.000007958515,2.400999e-8,0.000004391214,0.0003046169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1112587,"threshold_uncertainty_score":0.3880256,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2082181174","doi":"10.1210/jc.2004-0376","title":"Congenital Leptin Deficiency Due to Homozygosity for the Δ133G Mutation: Report of Another Case and Evaluation of Response to Four Years of Leptin Therapy","year":2004,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":276,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Alberta Children's Hospital","funders":"Health Research Board; Wellcome Trust","keywords":"Leptin; Missense mutation; Internal medicine; Medicine; Endocrinology; Frameshift mutation; Hyperinsulinemia; Mutation; Obesity; Biology; Genetics; Gene; Insulin resistance","retraction":null,"screen_n_in":null,"score":{"opus":0.1403618685461349,"gpt":0.4148122683175677,"spread":0.2744503997714327,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00718333,0.0001055263,0.0005283902,0.0001395034,0.00009512992,0.000008061003,0.0003291332,0.00006723042,0.00002738132],"category_scores_gemma":[0.007729965,0.00006573204,0.0002227858,0.0002546705,0.0004669095,0.00009870148,0.00006586212,0.0001996651,0.000002023327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001156857,"about_ca_system_score_gemma":0.0002735617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000057661,"about_ca_topic_score_gemma":0.00002775218,"domain_scores_codex":[0.9964998,0.001203042,0.001396017,0.0001793288,0.0005425502,0.0001792428],"domain_scores_gemma":[0.9940132,0.003650561,0.001214438,0.0003684964,0.0006833705,0.00006987117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02788589,0.001558253,0.002980528,0.00003415856,0.0003383691,0.001707589,0.008435369,0.0220046,0.6878597,0.005597461,0.0003035462,0.2412945],"study_design_scores_gemma":[0.007104875,0.001932461,0.6134372,0.00003269255,0.0004842327,0.01582581,0.0005765331,0.00013726,0.3527171,0.004223196,0.003375172,0.0001534599],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920776,0.000501696,0.002090488,0.00436114,0.0003265688,0.0005852475,0.00001253467,0.000003985638,0.00004069147],"genre_scores_gemma":[0.9978657,0.0001836087,0.001297595,0.0004693158,0.0001259177,0.000005813629,1.407604e-7,0.000009878673,0.00004205934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6104567,"threshold_uncertainty_score":0.9254049,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1979093310","doi":"10.1016/s0006-8993(03)02507-1","title":"Role of leptin in the control of feeding of goldfish Carassius auratus: interactions with cholecystokinin, neuropeptide Y and orexin A, and modulation by fasting","year":2003,"lang":"en","type":"article","venue":"Brain Research","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":276,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Endocrinology; Internal medicine; Leptin; Cholecystokinin; Neuropeptide Y receptor; Orexin; Neuropeptide; Orexin-A; Orexigenic; Chemistry; Hypothalamus; Receptor; Biology; Medicine; Obesity","retraction":null,"screen_n_in":null,"score":{"opus":0.03988527088225177,"gpt":0.3205023425149268,"spread":0.280617071632675,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001089422,0.00005980998,0.0001303983,0.0001635683,0.00008541621,0.00002981812,0.0001063918,0.00002612927,0.000007868959],"category_scores_gemma":[0.001395417,0.00004394843,0.00001262938,0.0004906186,0.0002878172,0.0001550997,0.00002784276,0.0002015905,2.932627e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001062926,"about_ca_system_score_gemma":0.00003163485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001626815,"about_ca_topic_score_gemma":0.00005739162,"domain_scores_codex":[0.9984838,0.0005717247,0.0002187948,0.0001889093,0.0003806386,0.0001561353],"domain_scores_gemma":[0.9982466,0.001371447,0.0001105235,0.000134558,0.0001056278,0.00003126118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006383809,0.00004734238,0.03276494,0.0000261634,0.000001966493,0.000001182668,0.0008392609,0.0001757571,0.9624685,0.001367172,0.0001099931,0.002133882],"study_design_scores_gemma":[0.001624274,0.0004144667,0.5212896,0.0001731767,0.000004825183,0.00002415306,0.002365355,0.01405476,0.4582504,0.000384916,0.001311066,0.0001030269],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995798,0.00003964275,0.0001115943,0.0004821052,0.000006758321,0.0002488756,0.00001022272,0.000003425282,0.003299366],"genre_scores_gemma":[0.9997531,0.00001341663,0.00006513389,0.00003882946,0.000007441458,0.000006991453,9.101286e-7,0.000006644373,0.0001075969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5042181,"threshold_uncertainty_score":0.1792165,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2162826365","doi":"10.2337/diabetes.52.2.252","title":"Role of Leptin in the Regulation of Glucagon-Like Peptide-1 Secretion","year":2003,"lang":"en","type":"article","venue":"Diabetes","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":268,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Leptin; Internal medicine; Endocrinology; Leptin receptor; Secretion; Glucagon-like peptide-1; Hyperinsulinemia; Enteroendocrine cell; Biology; Receptor; Hormone; Adipose tissue; Insulin resistance; Chemistry; Medicine; Insulin; Obesity; Endocrine system; Diabetes mellitus; Type 2 diabetes","retraction":null,"screen_n_in":null,"score":{"opus":0.01356133090188929,"gpt":0.229038528198058,"spread":0.2154771972961687,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003277627,0.000054888,0.000096292,0.00006596324,0.00003119969,0.000008427623,0.0001128609,0.00003597339,0.00006064196],"category_scores_gemma":[0.0002224916,0.00004218298,0.0000400354,0.0002709926,0.00007428441,0.0001072015,0.000009692774,0.00004444259,0.000008777834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007306499,"about_ca_system_score_gemma":0.00001286051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007196323,"about_ca_topic_score_gemma":0.000003822287,"domain_scores_codex":[0.9992191,0.0001705835,0.0001893431,0.0001212961,0.0001951007,0.0001045945],"domain_scores_gemma":[0.9994817,0.000180262,0.0001183828,0.0001812114,0.00002627634,0.00001220687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000002990925,0.00004669702,0.04407025,0.00001254256,6.638016e-7,4.733674e-8,0.0003875299,0.0001941969,0.9416153,0.01301023,0.00004114463,0.0006184078],"study_design_scores_gemma":[0.0001035355,0.00002846979,0.25548,0.00001623151,0.000002221345,1.576166e-7,0.00009888778,0.000584223,0.7375913,0.004682986,0.001377717,0.00003428496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919713,0.00004265683,0.00001123753,0.00006044916,0.00003478535,0.0001186569,0.000002501281,0.000007714038,0.007750743],"genre_scores_gemma":[0.9996979,0.000008681473,0.00008614417,0.00008232257,0.00001028734,0.000004481953,0.00000292833,0.000004172146,0.0001031015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2114097,"threshold_uncertainty_score":0.1720172,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2060896332","doi":"10.1038/nm.2421","title":"Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity","year":2011,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":266,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Mental Health; National Institutes of Health","keywords":"Internal medicine; Endocrinology; Leptin; Melanocortin; Peroxisome; Reactive oxygen species; Neuropeptide Y receptor; Hypothalamus; Biology; Peroxisome proliferator-activated receptor; Receptor; Agonist; Neuropeptide; Chemistry; Hormone; Cell biology; Medicine; Obesity","retraction":null,"screen_n_in":null,"score":{"opus":0.03165849255524136,"gpt":0.2820514523419473,"spread":0.2503929597867059,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004381453,0.0001428148,0.0003636088,0.0001705726,0.00008770074,0.000006617639,0.0001242423,0.0002285357,0.00007882778],"category_scores_gemma":[0.001750014,0.0001096018,0.00002771889,0.0003403404,0.0001499303,0.0001763754,0.00003299128,0.0004267403,0.000002113323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005486665,"about_ca_system_score_gemma":0.00002791261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005825016,"about_ca_topic_score_gemma":0.00009665659,"domain_scores_codex":[0.9986826,0.0001169503,0.0003253253,0.0003030167,0.0003786494,0.0001934872],"domain_scores_gemma":[0.9992245,0.0002027037,0.0002404432,0.0001447229,0.0001109671,0.00007659397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003065234,0.000145967,0.09671232,0.00002122093,0.00001061972,0.00001824137,0.002807457,5.687905e-7,0.8968733,0.002849548,0.00007361061,0.0001806039],"study_design_scores_gemma":[0.001324201,0.0003136206,0.6531827,0.0000854221,0.00001483695,0.00000381847,0.0001520961,0.0001296579,0.3440043,0.0006456301,0.00006457821,0.00007906926],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934537,0.000138227,0.00001709155,0.001179061,0.0001636431,0.000401092,0.00000952159,0.00003296812,0.004604714],"genre_scores_gemma":[0.9991284,0.00004292729,0.00003540535,0.0004962705,0.00009755616,0.000007279258,0.000006929501,0.000009328704,0.0001758801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5564704,"threshold_uncertainty_score":0.4469431,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2605514848","doi":"10.3389/fendo.2017.00073","title":"Appetite-Controlling Endocrine Systems in Teleosts","year":2017,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":265,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"FP7 Food, Agriculture and Fisheries, Biotechnology; Seventh Framework Programme; Japan Society for the Promotion of Science; Norges Forskningsråd; Japan Fisheries Research and Education Agency; Natural Sciences and Engineering Research Council of Canada; Göteborgs Universitet; Fisheries Agency","keywords":"Appetite; Endocrine system; Medicine; Endocrinology; Biology; Physiology; Internal medicine; Bioinformatics; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.07927857146275034,"gpt":0.3430925495158059,"spread":0.2638139780530556,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002570202,0.000628095,0.003117927,0.001519151,0.0001604492,0.0001305168,0.001473513,0.0003819005,0.00002346211],"category_scores_gemma":[0.0008053002,0.0005823507,0.000370414,0.0003880343,0.0003406031,0.000230263,0.0002938857,0.001087088,0.0001827419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003542357,"about_ca_system_score_gemma":0.0002068836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000162474,"about_ca_topic_score_gemma":0.00005745195,"domain_scores_codex":[0.995282,0.0007554702,0.001235873,0.001213068,0.0002999177,0.001213664],"domain_scores_gemma":[0.9975666,0.000360845,0.0007760247,0.001159204,0.00002505998,0.0001122975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003130383,0.0001125391,0.001224608,0.004035962,0.00002842843,0.00188478,0.00002924063,0.00009267151,0.000008042836,0.003393061,0.00120772,0.9879516],"study_design_scores_gemma":[0.0008814135,0.00004024721,0.0000781779,0.004493793,0.0000483279,0.0003614156,0.00001434622,0.0002158232,0.00003037081,0.000237969,0.9931215,0.0004766052],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001048375,0.9862508,0.0002148678,0.00006517073,0.005447069,0.001441138,0.00003762946,0.00009143865,0.006347062],"genre_scores_gemma":[0.0004018658,0.9965077,0.0002959574,0.00004527565,0.0003611896,0.0002815099,0.00002296981,0.000071004,0.002012507],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9919138,"threshold_uncertainty_score":0.9996628,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1983518876","doi":"10.1017/s0007114509991863","title":"Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-α","year":2009,"lang":"en","type":"article","venue":"British Journal Of Nutrition","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":265,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"Institute of Nutrition, Metabolism and Diabetes; Canadian Institutes of Health Research","keywords":"Ghrelin; Peptide YY; Internal medicine; Endocrinology; Adiponectin; Saline; Peptide hormone; Medicine; Glucagon; Glucagon-like peptide-1; Chemistry; Insulin; Hormone; Receptor; Neuropeptide; Neuropeptide Y receptor; Diabetes mellitus; Insulin resistance; Type 2 diabetes","retraction":null,"screen_n_in":null,"score":{"opus":0.01005896448783237,"gpt":0.2341140285537786,"spread":0.2240550640659462,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000191032,0.0001543907,0.0003615512,0.0001787425,0.0001739056,0.0001458829,0.0001221647,0.00009383368,0.000008939168],"category_scores_gemma":[0.0002924617,0.0001734814,0.000111274,0.0001780338,0.0001046137,0.0004311189,0.00002338967,0.0002987552,0.000002613469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003792303,"about_ca_system_score_gemma":0.00002464334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002351172,"about_ca_topic_score_gemma":0.000009124152,"domain_scores_codex":[0.9985507,0.0001555139,0.0004572786,0.0002501491,0.0003657647,0.0002205824],"domain_scores_gemma":[0.9989442,0.0002479092,0.0004190789,0.00008487648,0.0001380466,0.0001658579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003734321,0.000709339,0.0001769114,0.0001269917,0.00002050076,0.0006821182,0.0002239298,0.000008471781,0.9532695,0.0000480892,0.001296455,0.04306421],"study_design_scores_gemma":[0.003343202,0.002983151,0.2666088,0.001853697,0.00007655859,0.007544747,0.00003462462,0.00005476311,0.7146341,0.002077031,0.0005570488,0.0002322525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979732,0.0008750744,0.00009401031,0.0004614512,0.0002009205,0.0002366137,0.00002427104,0.00001880674,0.0001156408],"genre_scores_gemma":[0.9906899,0.008241266,0.0004950365,0.0003310957,0.0001556136,0.000001746581,0.000002362686,0.00001380135,0.00006913437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2664319,"threshold_uncertainty_score":0.7074367,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4247302633","doi":"10.1016/s0898-6568(02)00006-2","title":"Leptin signalling","year":2002,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":265,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"York University","funders":"","keywords":"Leptin; Signal transduction; Leptin receptor; Receptor; Biology; Gene isoform; Cell biology; Adipose tissue; Cytokine; SOCS3; Signalling pathways; Endocrinology; Gene; Obesity; Immunology; Genetics; STAT3","retraction":null,"screen_n_in":null,"score":{"opus":0.1048689460254172,"gpt":0.2960784465790585,"spread":0.1912095005536413,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004053219,0.0006676735,0.00148157,0.000333965,0.0003807017,0.0002479388,0.0008925457,0.0004877125,0.001634829],"category_scores_gemma":[0.0001595793,0.0006051589,0.0009383674,0.0006549376,0.0001126912,0.0001793006,0.0001490375,0.0007850832,0.003524307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001074465,"about_ca_system_score_gemma":0.00009546945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002292063,"about_ca_topic_score_gemma":2.790606e-7,"domain_scores_codex":[0.996271,0.0004002142,0.0009533338,0.00111263,0.0006308204,0.0006319622],"domain_scores_gemma":[0.9979853,0.0006405623,0.0006067182,0.0005065645,0.00004316821,0.000217668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002933818,0.0001241079,3.873277e-7,0.007767275,0.00003968463,0.0003504817,0.00009065885,0.0003350976,0.0162413,0.001572964,0.0003693887,0.9731057],"study_design_scores_gemma":[0.00009390337,0.00002741273,1.698635e-8,0.005882843,0.000223551,0.00002581934,0.000003233825,0.0009643515,0.01921651,0.0001372988,0.9727768,0.0006482274],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005144429,0.9853872,0.006574982,0.00001115053,0.000391551,0.0006198507,0.00001200256,0.0002424807,0.006709332],"genre_scores_gemma":[0.0002748064,0.9928156,0.0003983572,0.00007703114,0.0007802072,0.00003234088,0.00003617776,0.0001401493,0.005445382],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9724575,"threshold_uncertainty_score":0.99964,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1989130418","doi":"10.1210/jc.2004-0363","title":"Administration of Acylated Ghrelin Reduces Insulin Sensitivity, Whereas the Combination of Acylated Plus Unacylated Ghrelin Strongly Improves Insulin Sensitivity","year":2004,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":259,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Theratechnologies (Canada)","funders":"Roche Nederland","keywords":"Ghrelin; Endocrinology; Internal medicine; Insulin; Insulin resistance; Pancreatic hormone; Insulin sensitivity; Medicine; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.04591199200300388,"gpt":0.3428239258441968,"spread":0.2969119338411929,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00495703,0.0003642392,0.001359951,0.0002513321,0.0002642829,0.0000382892,0.0006182815,0.0003539472,0.00002600899],"category_scores_gemma":[0.006390955,0.0002288723,0.0005058564,0.0007371519,0.001580999,0.0004957615,0.0002238934,0.001515693,0.00001850649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004835581,"about_ca_system_score_gemma":0.0008270169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003075236,"about_ca_topic_score_gemma":0.0001373785,"domain_scores_codex":[0.9910048,0.004122817,0.003119623,0.0003959944,0.000872912,0.0004838441],"domain_scores_gemma":[0.9901619,0.004115317,0.003881277,0.0006369507,0.001035604,0.0001689771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007655479,0.002065107,0.0004100494,0.00003856942,0.0003304432,0.0001975298,0.0009951059,0.01423667,0.9427997,0.008714967,0.000117161,0.02243925],"study_design_scores_gemma":[0.007376603,0.001105957,0.1906493,0.0001122766,0.0004295557,0.0007462191,0.0002559242,0.00297612,0.7902277,0.005317905,0.0005530405,0.0002494465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891003,0.0005836703,0.0005336576,0.008080014,0.0009940295,0.0004864978,0.00003603426,0.00004010342,0.0001456595],"genre_scores_gemma":[0.9961234,0.002766559,0.0002873583,0.0003498704,0.000363566,0.000001802759,0.00000729961,0.00002938863,0.00007071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1902392,"threshold_uncertainty_score":0.9333141,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1976860473","doi":"10.1096/fj.02-0158rev","title":"Analysis of paradoxical observations on the association between leptin and insulin resistance","year":2002,"lang":"en","type":"review","venue":"The FASEB Journal","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":258,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"York University","funders":"","keywords":"Leptin; Insulin resistance; Internal medicine; Endocrinology; Insulin; Diabetes mellitus; Obesity; Mediator; Glucose homeostasis; Leptin receptor; Lipoatrophy; Hormone; Homeostasis; Medicine; Biology; Immunology","retraction":null,"screen_n_in":null,"score":{"opus":0.1312652113836405,"gpt":0.3186828554956023,"spread":0.1874176441119618,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001196751,0.0001679788,0.0007234528,0.0001916403,0.0004853854,0.0001178671,0.0004364573,0.0001315846,0.000149513],"category_scores_gemma":[0.001057575,0.00008238661,0.0004465233,0.001179999,0.00009580852,0.00007318553,0.000042335,0.0006221955,0.00002545646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001185502,"about_ca_system_score_gemma":0.00004968892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000180172,"about_ca_topic_score_gemma":0.000006175698,"domain_scores_codex":[0.9975643,0.0009348042,0.0005861578,0.0001849119,0.0005676983,0.0001621052],"domain_scores_gemma":[0.9952353,0.003198369,0.001146896,0.0003043715,0.00005842681,0.00005669679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007387425,0.0005428509,0.01386864,0.001729012,0.006018932,0.000039542,0.001493585,0.0003526813,0.000797221,0.03700168,0.01709424,0.9209877],"study_design_scores_gemma":[0.0001624407,0.00004796722,0.02806684,0.001435489,0.005737924,0.000008254205,0.00002140585,0.0001022165,0.0003725825,0.0005104711,0.9632927,0.0002417593],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05084639,0.9412084,0.00009199359,0.004113074,0.0001604422,0.0005548166,0.0002854827,0.00002411038,0.002715323],"genre_scores_gemma":[0.01190826,0.9859982,0.00001821552,0.000137133,0.0002100568,0.000004453088,0.000007608463,0.00001066748,0.001705423],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9461984,"threshold_uncertainty_score":0.3733242,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144661178","doi":"10.1136/jmg.2004.027698","title":"Melanocortin-1 receptor gene variants affect pain and μ-opioid analgesia in mice and humans","year":2005,"lang":"en","type":"article","venue":"Journal of Medical Genetics","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":255,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse; Canada Research Chairs; Children's Miracle Network Hospitals","keywords":"Opioid; μ-opioid receptor; Morphine; Melanocortin; Melanocortin 1 receptor; Analgesic; Opioid receptor; Pharmacogenetics; Pharmacology; Medicine; Receptor; Nociception; Genotype; Internal medicine; Biology; Endocrinology; Allele; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0180463517563162,"gpt":0.2787956066750193,"spread":0.2607492549187032,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001689384,0.00009549718,0.0002057174,0.0001182718,0.000052796,0.00003699066,0.0001935021,0.0001242721,0.0001606509],"category_scores_gemma":[0.0009287497,0.00007736652,0.00003441705,0.0001301382,0.0001230826,0.00007256773,0.00005822265,0.0002731236,0.000004956873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002173556,"about_ca_system_score_gemma":0.00007715484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002874506,"about_ca_topic_score_gemma":0.00001810006,"domain_scores_codex":[0.998269,0.0002857627,0.0004343686,0.0001574758,0.0006801953,0.0001731618],"domain_scores_gemma":[0.9990988,0.0003082855,0.0002035082,0.0000798391,0.00003084539,0.0002787082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001697423,0.0004301853,0.06943365,0.00009085474,0.00002387782,0.0004154708,0.001368181,0.000159489,0.626065,0.0005287316,0.003728453,0.2975864],"study_design_scores_gemma":[0.00433007,0.001474053,0.6305174,0.0004040543,0.00005392681,0.0009639409,0.0001385469,0.01347979,0.2774254,0.00102923,0.069709,0.0004746295],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945837,0.001078856,0.0009068964,0.003123657,0.0001099071,0.00006976655,0.000001544856,0.00000442765,0.0001212806],"genre_scores_gemma":[0.9905658,0.004878195,0.002772776,0.001271501,0.0004297384,5.257913e-7,3.207779e-7,0.000008691907,0.00007240443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5610837,"threshold_uncertainty_score":0.3154915,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2055212297","doi":"10.1017/s0007114509990729","title":"Experimental rat models to study the metabolic syndrome","year":2009,"lang":"en","type":"review","venue":"British Journal Of Nutrition","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":254,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Metabolic syndrome; Endocrinology; Internal medicine; Medicine; Hyperinsulinism; Diabetes mellitus; Context (archaeology); Insulin resistance; Spontaneously hypertensive rat; Obesity; Genetic model; Leptin; Insulin; Genetically modified mouse; Transgene; Biology; Blood pressure; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.0909239812516042,"gpt":0.337661406386151,"spread":0.2467374251345468,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004935725,0.0002322777,0.00108261,0.0002238793,0.0002740532,0.0003350923,0.0006212626,0.0001045545,0.00005076092],"category_scores_gemma":[0.00006951762,0.0001936271,0.0005331003,0.0004742948,0.00003970116,0.0004615178,0.00006287955,0.0004449796,0.00003445248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007117668,"about_ca_system_score_gemma":0.00006352758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006302027,"about_ca_topic_score_gemma":0.000001330208,"domain_scores_codex":[0.9973056,0.0006452489,0.0008669286,0.0002849714,0.000684108,0.0002131928],"domain_scores_gemma":[0.9988392,0.0001223952,0.0005875753,0.0002107453,0.00009428112,0.0001457975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001611994,0.003193715,1.070858e-7,0.0002358136,0.0000376176,0.002022796,0.0001108545,0.00001799624,0.000152502,0.0001612504,0.002182304,0.9918689],"study_design_scores_gemma":[0.0009462786,0.0009317293,0.00003802824,0.009239614,0.0004081724,0.04749944,0.0001419726,0.00000465435,0.001128246,0.0006694773,0.9386531,0.0003393158],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01314107,0.9849868,0.00006859267,0.00007012096,0.0003697076,0.001218305,0.00001839042,0.00001643501,0.000110622],"genre_scores_gemma":[0.01699104,0.9821467,0.000153757,0.0001932482,0.0003702492,0.00003806661,0.000002975941,0.00002706153,0.00007687556],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9915296,"threshold_uncertainty_score":0.7895885,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}