{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":251,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":251,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"40c92d18b9fe","filters":{"topic":"Synthesis and Biological Evaluation"}},"results":[{"id":"W2258138802","doi":"10.1002/anie.201510675","title":"Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere","year":2016,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":187,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre for Drug Research and Development","funders":"Australian Research Council; State Government of Victoria","keywords":"Cubane; Bioisostere; Geology; Chemistry; Crystallography","retraction":null,"screen_n_in":null,"score":{"opus":0.04138783950913441,"gpt":0.2751303973813545,"spread":0.2337425578722201,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002101909,0.000173416,0.0001489089,0.00005433219,0.00007449945,0.00005808358,0.0002574863,0.0001730668,0.01589286],"category_scores_gemma":[0.001052393,0.0001134857,0.0001242552,0.00005889829,0.00005650368,0.0002677281,0.00006644056,0.0000780076,0.0004286229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001932232,"about_ca_system_score_gemma":0.0000291771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002063953,"about_ca_topic_score_gemma":0.00000394418,"domain_scores_codex":[0.9986732,0.00001649615,0.0003025635,0.0003633111,0.0004434927,0.0002009426],"domain_scores_gemma":[0.9989616,0.0003831756,0.0001958554,0.0001859636,0.0001976595,0.00007578871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005355411,0.00007294237,0.001057122,0.00001212591,0.00005543714,0.000005101635,0.00002641783,3.800656e-7,0.9526018,0.0002551354,0.003044223,0.04281577],"study_design_scores_gemma":[0.0005265957,0.00002487859,0.0006971337,0.0002227786,0.00002386512,0.00002249605,0.00007120548,0.00001351957,0.9745617,0.004513761,0.01913254,0.0001895209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8783932,0.00009946043,0.0009963261,0.007226103,0.0007548797,0.00008955967,0.0002306975,0.0002397634,0.11197],"genre_scores_gemma":[0.9938816,0.0001267572,0.0003167271,0.0003876227,0.002256307,0.00006543409,0.0001935102,0.00001896643,0.002753068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1154884,"threshold_uncertainty_score":0.9850067,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2004355958","doi":"10.1021/ja017136x","title":"Practical and Highly Regio- and Stereoselective Synthesis of 2-Substituted Dihydropyridines and Piperidines:  Application to the Synthesis of (−)-Coniine","year":2001,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":167,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Université de Montréal","funders":"","keywords":"Citation; Stereoselectivity; Computer science; Information retrieval; Library science; World Wide Web; Chemistry; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02000445509544524,"gpt":0.2833552908580588,"spread":0.2633508357626135,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004447685,0.0001401871,0.0004571342,0.00001763889,0.0000858694,0.00003095975,0.0001798016,0.00007650277,0.00001104266],"category_scores_gemma":[0.002723397,0.00007262809,0.0001658712,0.0002647652,0.0007669499,0.000090523,0.0001147952,0.0001835455,1.794431e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005381133,"about_ca_system_score_gemma":0.00004719285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000126273,"about_ca_topic_score_gemma":0.000004020246,"domain_scores_codex":[0.9988933,0.00007677579,0.0004298092,0.0001852197,0.0002774567,0.0001374522],"domain_scores_gemma":[0.9964574,0.002192414,0.0008621187,0.0001944448,0.0002078438,0.00008580046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002764653,0.00009257712,0.009205233,0.00003795864,0.0001486943,4.046198e-7,0.0001414809,0.000003872418,0.9689185,0.00003150553,0.0003581785,0.02078513],"study_design_scores_gemma":[0.0001850101,0.00006185143,0.01761106,0.0001393275,0.0003206092,0.0001362521,0.0008734228,0.0008891025,0.9783006,0.0001409087,0.001211208,0.0001306069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903904,0.0001511146,0.0002562643,0.009036332,0.00001088787,0.00008712613,0.00001149245,0.000005758807,0.00005067654],"genre_scores_gemma":[0.9961224,0.00121941,0.002348142,0.0001598256,0.0001173116,0.000013871,3.699043e-7,0.000009192931,0.000009506062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02065452,"threshold_uncertainty_score":0.3260358,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2100648759","doi":"10.3998/ark.5550190.0013.108","title":"Synthesis of heterocyclic compounds based on isatin through 1,3-dipolar cycloaddition reactions","year":2012,"lang":"en","type":"article","venue":"ARKIVOC","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":145,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"","keywords":"Isatin; Chemistry; Cycloaddition; 1,3-Dipolar cycloaddition; Combinatorial chemistry; Organic chemistry; Computational chemistry; Catalysis","retraction":null,"screen_n_in":null,"score":{"opus":0.04804641978259167,"gpt":0.2842232967319141,"spread":0.2361768769493224,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002086838,0.0001300839,0.0001870725,0.00003142657,0.00009512648,0.00001062194,0.0001041751,0.0001391834,0.002527292],"category_scores_gemma":[0.0004902698,0.0001023507,0.0001273863,0.00008207464,0.00006597002,0.0001217696,0.00001521297,0.000104903,0.0001276024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006400898,"about_ca_system_score_gemma":0.000007045422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006546277,"about_ca_topic_score_gemma":0.000002376,"domain_scores_codex":[0.9990175,0.00007885091,0.000282508,0.0001686575,0.000240449,0.0002119786],"domain_scores_gemma":[0.9985273,0.0009107513,0.0001804871,0.0002912541,0.00003576159,0.00005442903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001045324,0.0009274918,0.01236413,0.00009449628,0.00005141907,4.629381e-7,0.0001031981,0.00005776298,0.9618831,0.0005977383,0.002000595,0.02181504],"study_design_scores_gemma":[0.0001963363,0.00003703662,0.01498029,0.0001461848,0.00005281252,0.000002178914,0.000102052,0.000793569,0.9517856,0.0003475292,0.0313888,0.000167579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8754073,0.0001079502,0.0002416186,0.0004127707,0.0001252111,0.0000748752,0.00009107003,0.00009942526,0.1234397],"genre_scores_gemma":[0.9985406,0.00002722679,0.000774989,0.0002252619,0.0002157482,0.00005052901,0.00006618841,0.00001242999,0.00008702142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1233527,"threshold_uncertainty_score":0.9983845,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2165648585","doi":"10.1016/j.plipres.2005.04.002","title":"Biochemistry, biology and chemistry of the 5-lipoxygenase product 5-oxo-ETE","year":2005,"lang":"en","type":"review","venue":"Progress in Lipid Research","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":138,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Christie (Canada); McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Lipoxygenase; Chemistry; Biochemistry; Enzyme","retraction":null,"screen_n_in":null,"score":{"opus":0.186708237593418,"gpt":0.4766432646981967,"spread":0.2899350271047787,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002484465,0.0003790606,0.001078555,0.00008567121,0.0001181524,0.00004526543,0.001100305,0.0007639813,0.0007514987],"category_scores_gemma":[0.00186245,0.0002118837,0.0002751835,0.0005912181,0.001478567,0.0000254451,0.0008512959,0.001348592,0.00001439504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001809688,"about_ca_system_score_gemma":0.0004741923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008707573,"about_ca_topic_score_gemma":0.000001704998,"domain_scores_codex":[0.9966178,0.0004360774,0.0008215561,0.0009204114,0.0005632375,0.0006409057],"domain_scores_gemma":[0.9976554,0.0006459277,0.0003701196,0.0009989036,0.0002246729,0.0001049754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001364755,0.000157776,0.0007495351,0.01545051,0.00005057328,0.000001281781,0.00001178038,4.079946e-8,0.001421818,0.000008774258,0.0001370317,0.9819973],"study_design_scores_gemma":[0.0001934275,0.00001982495,0.00002861,0.006850239,0.00006902681,0.00003156104,0.00002012272,0.00001117808,0.02625977,0.00005600494,0.9661577,0.0003025596],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004085573,0.9929764,5.071023e-8,0.000233521,0.00005985315,0.0004804175,0.0001176577,0.00002266575,0.002023821],"genre_scores_gemma":[0.005612257,0.9918449,0.00007651671,0.000002904227,0.001147323,0.0005580888,0.0001159026,0.00002992736,0.0006121646],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9816947,"threshold_uncertainty_score":0.8640367,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1983316037","doi":"10.1074/jbc.m503076200","title":"Structure and Mechanism of the Alkyl Hydroperoxidase AhpC, a Key Elementof the Mycobacterium tuberculosis Defense System against OxidativeStress","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":98,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo; European Commission","keywords":"Mycobacterium tuberculosis; Mechanism (biology); Tuberculosis; Alkyl; Microbiology; Chemistry; Key (lock); Biology; Medicine; Pathology; Organic chemistry; Ecology; Philosophy","retraction":null,"screen_n_in":null,"score":{"opus":0.01744183420795121,"gpt":0.2296794038372884,"spread":0.2122375696293372,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005004085,0.0002294387,0.0003902005,0.00001082127,0.0001295085,0.00003958323,0.0004773341,0.0003117756,0.0004761351],"category_scores_gemma":[0.0004538938,0.00009151186,0.000245791,0.00009065183,0.0002373128,0.00005859782,0.000173195,0.0004084128,0.000001090889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009481684,"about_ca_system_score_gemma":0.0000383542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002364039,"about_ca_topic_score_gemma":7.3647e-7,"domain_scores_codex":[0.9983975,0.0001283151,0.0006974924,0.0002203941,0.0003336197,0.0002227221],"domain_scores_gemma":[0.9983797,0.0002485832,0.0008018899,0.0002820757,0.0001824598,0.0001052943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000869443,0.00007008408,0.001791726,0.0001025892,0.00009437024,0.00000361537,0.00006321475,0.00001712305,0.9950435,0.00006668917,0.00004481929,0.002615319],"study_design_scores_gemma":[0.0004148298,0.0000477578,0.002429122,0.000203202,0.00007949252,0.0001319816,0.0006296985,0.0002066401,0.9948073,0.0001385635,0.0007740488,0.000137374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970759,0.0006797807,0.00001059193,0.0007651153,0.00004410748,0.0000688791,0.00008061629,0.00001308214,0.001261898],"genre_scores_gemma":[0.9989417,0.0002445139,0.0001839923,0.000143906,0.0004154939,0.000004188845,0.000008509386,0.000007994852,0.00004969041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002477945,"threshold_uncertainty_score":0.5213345,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1985634736","doi":"10.1021/jo801411p","title":"Povarov Reactions Involving 3-Aminocoumarins: Synthesis of 1,2,3,4-Tetrahydropyrido[2,3-<i>c</i>]coumarins and Pyrido[2,3-<i>c</i>]coumarins","year":2008,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":77,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Tautomer; Diastereomer; Chemistry; Cycloaddition; Condensation; Medicinal chemistry; Stereochemistry; Organic chemistry; Catalysis; Physics","retraction":null,"screen_n_in":null,"score":{"opus":0.02434862651169116,"gpt":0.2242580305217309,"spread":0.1999094040100398,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001145294,0.0003484614,0.0006622518,0.00006111183,0.0003398836,0.00002815373,0.0006852311,0.0002964714,0.004824895],"category_scores_gemma":[0.002282989,0.0002350801,0.0002544683,0.0002852439,0.000533935,0.0002119582,0.0002236666,0.0006807618,0.000009758845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001948885,"about_ca_system_score_gemma":0.000269965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007028255,"about_ca_topic_score_gemma":0.00001028841,"domain_scores_codex":[0.9973909,0.00009258635,0.001216925,0.0002717191,0.0006715617,0.0003562838],"domain_scores_gemma":[0.9959682,0.001537153,0.001324386,0.0005861226,0.0003883605,0.0001957314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001397129,0.0002590588,0.005916626,0.0002239751,0.0002285613,0.00002460023,0.0002870101,0.00001563118,0.9886847,0.000008122724,0.0003721755,0.003839848],"study_design_scores_gemma":[0.0006236521,0.00005671812,0.005692798,0.0002956984,0.0003897221,0.002886623,0.001025526,0.0001426641,0.9863321,0.0002305829,0.002006447,0.0003174498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878272,0.001580073,0.00006703889,0.0003768452,0.00008250894,0.00006588143,0.00001939699,0.00003919117,0.009941847],"genre_scores_gemma":[0.9924361,0.005835361,0.0003150069,0.00005806985,0.0004096508,0.000004759504,0.000004246914,0.00004268637,0.0008940785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009047769,"threshold_uncertainty_score":0.9960848,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029365371","doi":"10.1007/s00253-009-2427-4","title":"Biotransformation of nicotine by microorganism: the case of Pseudomonas spp.","year":2010,"lang":"en","type":"review","venue":"Applied Microbiology and Biotechnology","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":77,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Key Research and Development Program of China; McMaster University","keywords":"Nicotine; Arthrobacter; Biotransformation; Pseudomonas; Catabolism; Alkaloid; Biology; Biodegradation; Microorganism; Metabolic pathway; Bacteria; Microbiology; Chemistry; Biochemistry; Enzyme; Botany; Genetics; Ecology","retraction":null,"screen_n_in":null,"score":{"opus":0.01604320450691055,"gpt":0.2563588043202272,"spread":0.2403155998133166,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000393203,0.0003599204,0.001293521,0.0001012756,0.00009479892,0.000004773936,0.0004004696,0.003599698,0.0002972148],"category_scores_gemma":[0.00005184747,0.0001993693,0.0001896401,0.0001903659,0.001349345,0.00001122784,0.0001455488,0.0008327273,0.00001804825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001608175,"about_ca_system_score_gemma":0.00005305713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001929749,"about_ca_topic_score_gemma":0.00001898459,"domain_scores_codex":[0.9984049,0.0000569138,0.0008546548,0.0004092917,0.00002421371,0.0002500242],"domain_scores_gemma":[0.9983497,0.0003574834,0.0007846589,0.0004466605,0.00003854886,0.00002294067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007847491,0.00004079024,3.040368e-7,0.001184458,0.00006749093,0.000001649087,0.000006407452,3.370185e-9,0.57162,0.001323547,0.000120352,0.4256272],"study_design_scores_gemma":[0.0001400673,0.00003377009,3.913337e-8,0.0001763291,0.0002926019,0.001394922,0.00004051653,2.256633e-7,0.4955448,0.0001260484,0.5021088,0.0001419458],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01476229,0.9832558,0.00004623466,0.0002371478,0.00005766098,0.0004048206,0.0006411249,0.00005661701,0.0005382939],"genre_scores_gemma":[0.02373111,0.9753167,0.0002551619,0.00003227125,0.00002902707,0.00004034185,0.0005417131,0.00001985528,0.00003382719],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5019884,"threshold_uncertainty_score":0.9976938,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3013159324","doi":"10.1038/s41467-020-14949-y","title":"A lipophilic cation protects crops against fungal pathogens by multiple modes of action","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":66,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; University of Exeter; Research Councils UK; Canadian Institute for Advanced Research","keywords":"Fungicide; Biology; Septoria; Mycosphaerella graminicola; Reactive oxygen species; Blast disease; Magnaporthe grisea; Crop; Pesticide; Antifungal; Singlet oxygen; Fungal pathogen; Microbiology; Chemistry; Pathogen; Oryza sativa; Biochemistry; Botany; Agronomy; Oxygen; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.08268203531999636,"gpt":0.3135228908770711,"spread":0.2308408555570748,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001422347,0.0001087691,0.0001458706,0.0000209468,0.0001690788,0.00001719008,0.0005207602,0.0003538163,0.00006365178],"category_scores_gemma":[0.001329844,0.00009284235,0.00007995251,0.0001988077,0.00007896503,0.00007615221,0.0001255641,0.0005278487,0.00001177906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004753371,"about_ca_system_score_gemma":0.00003819708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001755372,"about_ca_topic_score_gemma":0.00005764038,"domain_scores_codex":[0.9991726,0.0001044871,0.0002505785,0.0001887745,0.000177565,0.0001059509],"domain_scores_gemma":[0.9985595,0.0002676867,0.0002004682,0.0007188098,0.0001918023,0.00006172831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002595438,0.0001356322,0.002134645,0.0000343788,0.00001912394,7.360732e-8,0.0001473479,0.00003182244,0.9786215,0.0001925553,0.0006228905,0.01803405],"study_design_scores_gemma":[0.000408194,0.0000428827,0.004620421,0.00004905431,0.00004160163,0.00000126924,0.0003855884,0.04090291,0.9347793,0.0001052678,0.01844882,0.0002146317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838701,0.003671467,0.0002342536,0.007530114,0.00002415267,0.0003097788,0.0002467514,0.0001506569,0.003962751],"genre_scores_gemma":[0.9968721,0.0005121922,0.001592924,0.0003119155,0.0000647812,0.0001030821,0.0004960517,0.00001169699,0.00003520502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04384217,"threshold_uncertainty_score":0.3786001,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2055075583","doi":"10.1016/j.bmc.2013.12.024","title":"Synthesis of novel indenoquinoxaline derivatives as potent α-glucosidase inhibitors","year":2013,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":64,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Winnipeg","funders":"","keywords":"Chemistry; Carbon-13 NMR; Mass spectrometry; Stereochemistry; Proton NMR; Elemental analysis; Chemical synthesis; Combinatorial chemistry; In vitro; Organic chemistry; Biochemistry; Chromatography","retraction":null,"screen_n_in":null,"score":{"opus":0.02308128710649296,"gpt":0.2513034637131077,"spread":0.2282221766066148,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002967629,0.0002999611,0.0004390658,0.00002899639,0.00007358845,0.00002121863,0.0003632939,0.0003540752,0.01502691],"category_scores_gemma":[0.002402354,0.0002202619,0.0001413381,0.0001956278,0.0002885679,0.00008109416,0.0001196477,0.0002435457,0.00009135151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067608,"about_ca_system_score_gemma":0.0001340738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001577725,"about_ca_topic_score_gemma":6.741377e-7,"domain_scores_codex":[0.9979644,0.00002093863,0.00064242,0.000443144,0.0005938138,0.0003352305],"domain_scores_gemma":[0.9983995,0.0003818364,0.0003656494,0.0003998682,0.0002324738,0.0002206965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003199105,0.0003224869,0.001265267,0.0002250064,0.00006400423,0.000003365881,0.00006715831,5.537019e-7,0.9860701,0.000009870734,0.0003870211,0.01155319],"study_design_scores_gemma":[0.0005063973,0.00003438883,0.002688445,0.0003329586,0.00008036437,0.00003773264,0.001101137,0.00008855477,0.9943667,0.00009715844,0.0004115626,0.0002545926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882542,0.0004844366,0.00005561692,0.0009959291,0.00005325432,0.0001024935,0.00002483915,0.00007959674,0.009949659],"genre_scores_gemma":[0.9984034,0.0000702367,0.0002779169,0.0001409693,0.0005083766,0.00005603837,0.00003872328,0.00002701881,0.0004773542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01493555,"threshold_uncertainty_score":0.9858735,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2075375774","doi":"10.1016/j.aca.2008.09.016","title":"A determinative and confirmatory method for residues of the metabolites of carbadox and olaquindox in porcine tissues","year":2008,"lang":"en","type":"article","venue":"Analytica Chimica Acta","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":62,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canadian Food Inspection Agency","funders":"","keywords":"Chemistry; Determinative; Chromatography","retraction":null,"screen_n_in":null,"score":{"opus":0.03287154179967883,"gpt":0.3044613058480031,"spread":0.2715897640483242,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002913828,0.00009281893,0.0003361973,0.00003965563,0.00003400853,0.000003765239,0.00009840656,0.00007651324,0.00004544258],"category_scores_gemma":[0.0007294745,0.0000551561,0.00005779,0.00007623835,0.0002128605,0.00003452558,0.00005125369,0.00005799823,6.469974e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006841478,"about_ca_system_score_gemma":0.00002384898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003183355,"about_ca_topic_score_gemma":0.00002034369,"domain_scores_codex":[0.9992851,0.00006600779,0.0002778414,0.0001661733,0.0001063647,0.00009849428],"domain_scores_gemma":[0.9987656,0.0008150938,0.0001687362,0.0001518042,0.00007230064,0.00002645247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008149636,0.00005699739,0.04671066,0.000111385,0.00005926438,4.93537e-7,0.0006685978,7.260769e-8,0.9506297,0.0002764188,0.00005225834,0.00135273],"study_design_scores_gemma":[0.0004359282,0.0000395061,0.1166291,0.0000675927,0.000105375,0.000007908009,0.0002307297,0.001723158,0.8793012,0.001117258,0.0002637803,0.00007846611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983593,0.0002448248,0.000004199975,0.0003578217,0.000005564011,0.0001032016,0.00003100847,0.000004517699,0.0008895163],"genre_scores_gemma":[0.9980128,0.0002446707,0.001565933,0.00003325116,0.00001898122,0.00001002387,0.000003345443,0.000005109143,0.0001058824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07132839,"threshold_uncertainty_score":0.22492,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3176631466","doi":"10.1039/d1nj01442k","title":"Recent advances in the transition metal catalyzed synthesis of quinoxalines: a review","year":2021,"lang":"en","type":"review","venue":"New Journal of Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":61,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Acadia University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Delhi; Mitacs; Beatrice Hunter Cancer Research Institute","keywords":"Chemistry; Quinoxaline; Combinatorial chemistry; Catalysis; Transition metal; Organic synthesis; Nanotechnology; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.06746999148067057,"gpt":0.3551378149311372,"spread":0.2876678234504666,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001411614,0.0003239426,0.00232763,0.00003147268,0.0000215187,0.00001701066,0.0006072107,0.0003540647,0.002444973],"category_scores_gemma":[0.002208619,0.0001755988,0.001139002,0.0003347205,0.00005535111,0.00009378599,0.00002276562,0.000578694,0.000002066016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001040928,"about_ca_system_score_gemma":0.0006394407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001776158,"about_ca_topic_score_gemma":0.000001049042,"domain_scores_codex":[0.9969285,0.0002315139,0.00182774,0.0002310159,0.0006146886,0.000166499],"domain_scores_gemma":[0.9963738,0.0009604422,0.001998585,0.000344328,0.0002492151,0.00007360101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001111083,0.0001173661,2.979413e-7,0.04171528,0.0001155135,0.00002566315,0.00001868702,7.715828e-7,0.001198591,6.405136e-7,0.0004003576,0.9563957],"study_design_scores_gemma":[0.0001392051,0.000007047361,1.387695e-7,0.1291994,0.001914588,0.0004763612,0.00009875305,3.467994e-7,0.01145817,0.00002208928,0.8565161,0.0001678092],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006621009,0.9976889,0.00000526885,0.0003975804,0.00004761455,0.00009748475,0.00003491508,0.00000374222,0.001658227],"genre_scores_gemma":[0.00003332535,0.999209,0.00008174409,0.00005921336,0.0004683088,0.00002104348,0.00007870256,0.00001635546,0.0000322925],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9562279,"threshold_uncertainty_score":0.9984669,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2003989644","doi":"10.1016/j.bmc.2005.02.034","title":"Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents","year":2005,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":61,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Oxadiazole; Structural isomer; Sodium nitrite; Stereochemistry; Sodium azide; Furoxan; Nitric oxide; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03616452904586519,"gpt":0.2719973252454984,"spread":0.2358327961996332,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001677056,0.0005378886,0.0007335441,0.00008416074,0.0002048351,0.00005878319,0.0003611843,0.0005282466,0.005048743],"category_scores_gemma":[0.002881671,0.0004242811,0.0001590824,0.0002153166,0.0006434783,0.0001531579,0.0002227319,0.0003826137,0.00003172775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002362853,"about_ca_system_score_gemma":0.0002323348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000724897,"about_ca_topic_score_gemma":0.000002557331,"domain_scores_codex":[0.9962851,0.0001577915,0.0009394871,0.000914918,0.001143531,0.0005591907],"domain_scores_gemma":[0.9977743,0.0004962687,0.000510567,0.0004525651,0.0003429299,0.000423345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001594716,0.0002240645,0.008219538,0.0002053934,0.0001274452,0.00001151517,0.00004791243,0.000006499741,0.9405626,0.000009186165,0.0002965184,0.05012985],"study_design_scores_gemma":[0.001514303,0.00005013875,0.02882812,0.0002857523,0.0006386752,0.000260833,0.0007109358,0.001887344,0.9639583,0.0003100378,0.001030049,0.000525468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917423,0.004897596,0.00002122406,0.0004506772,0.0000550366,0.0002324673,0.00007571272,0.000111285,0.002413728],"genre_scores_gemma":[0.997305,0.001050207,0.0002724215,0.0002118431,0.0008827461,0.0000693951,0.00008218598,0.00003937793,0.0000867858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04960438,"threshold_uncertainty_score":0.9998209,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2179461628","doi":"10.1016/j.bmcl.2004.01.028","title":"Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA–FtsZ interaction","year":2004,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":60,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Women's Health Research Institute","funders":"Zhejiang Pharmaceutical Association","keywords":"FtsZ; Chemistry; Stereochemistry; Biochemistry; Cytoskeleton; Cell","retraction":null,"screen_n_in":null,"score":{"opus":0.03170809101371981,"gpt":0.2379478597943535,"spread":0.2062397687806337,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003815739,0.0001928354,0.0003318226,0.00002410298,0.00005971091,0.000008440154,0.0002650626,0.0001919837,0.0004742691],"category_scores_gemma":[0.0008282369,0.0001307481,0.00009644008,0.0001708014,0.0003950435,0.00005033048,0.00008346642,0.0002227324,0.000002903885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001239555,"about_ca_system_score_gemma":0.00006996711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005321684,"about_ca_topic_score_gemma":6.968751e-7,"domain_scores_codex":[0.9985639,0.00004623025,0.0004853969,0.0002905033,0.000414815,0.0001991132],"domain_scores_gemma":[0.9987992,0.0003429908,0.0004141825,0.0003059613,0.00006576461,0.00007192099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001033834,0.0001102097,0.0007418431,0.000246118,0.0000610192,0.000001543961,0.0001316434,0.00001336746,0.995611,0.00000247717,0.00007599999,0.002901454],"study_design_scores_gemma":[0.000514059,0.00001914868,0.002207143,0.0005949268,0.000124787,0.00003126473,0.0003463239,0.00001336189,0.9958964,0.00005881546,0.00005932973,0.0001344186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956357,0.0002166517,0.0002501945,0.003385102,0.00007441224,0.00009078237,0.000006402649,0.00002617978,0.000314598],"genre_scores_gemma":[0.9991759,0.00006618416,0.0003005531,0.0001960469,0.0002168883,0.00001336297,0.000004315507,0.00001508569,0.0000116477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00354024,"threshold_uncertainty_score":0.5331755,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W198746999","doi":"10.1007/978-3-540-69248-5_9","title":"Molecular Genetics of Nicotine Metabolism","year":2009,"lang":"en","type":"review","venue":"Handbook of experimental pharmacology","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":60,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"CYP2A6; Nicotine; Cytochrome P450; Genetics; Drug metabolism; Biology; Metabolism; Genetic variation; Enzyme; Catechol-O-methyl transferase; Flavin-containing monooxygenase; Molecular genetics; Monooxygenase; Biochemistry; Gene; Allele; Neuroscience; CYP1A2","retraction":null,"screen_n_in":null,"score":{"opus":0.07214904974916038,"gpt":0.4050955057408523,"spread":0.3329464559916919,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013455,0.0003556103,0.001708342,0.00007856482,0.00002140177,0.000003730781,0.0003679582,0.0004134724,0.005123036],"category_scores_gemma":[0.00001695596,0.0002720318,0.0005822205,0.00008027911,0.0001791947,0.00001662324,0.0001204291,0.0001802059,0.00001765463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005282298,"about_ca_system_score_gemma":0.00009465197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003379504,"about_ca_topic_score_gemma":4.662746e-8,"domain_scores_codex":[0.9982018,0.0001397246,0.0008672068,0.000352158,0.0002114123,0.0002276716],"domain_scores_gemma":[0.9988067,0.0001243677,0.0007185105,0.0002187085,0.00005744194,0.00007423814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000218269,0.0003220714,2.353248e-7,0.0009501252,0.000207897,0.000003270024,0.00001405319,9.417552e-7,0.700043,0.00003252583,0.000169045,0.298235],"study_design_scores_gemma":[0.0003527159,0.00007144992,1.423679e-7,0.001088629,0.0007235743,0.000007594373,0.000007848708,0.000006907019,0.6957833,0.00001742671,0.3017762,0.0001641809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001736966,0.9945365,0.000008408897,0.000002985197,0.0001628092,0.0002554207,0.00004852756,0.00001915102,0.003229196],"genre_scores_gemma":[0.00284178,0.9962491,0.000425728,0.0000473549,0.0001881472,0.000074657,0.00009238464,0.00002760944,0.0000532842],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3016071,"threshold_uncertainty_score":0.9999732,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1980613884","doi":"10.1016/j.talanta.2012.10.059","title":"Novel hapten synthesis for antibody production and development of an enzyme-linked immunosorbent assay for determination of furaltadone metabolite 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ)","year":2012,"lang":"en","type":"article","venue":"Talanta","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":59,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Queen's University; National Natural Science Foundation of China; China Postdoctoral Science Foundation; Queen's University Belfast","keywords":"Hapten; Chemistry; Acetic acid; Chromatography; Combinatorial chemistry; Metabolite; Heterologous; Antibody; Stereochemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.06485444105398101,"gpt":0.3156303592319727,"spread":0.2507759181779917,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001380611,0.000181881,0.0004005058,0.00008517905,0.00009429481,0.00001241967,0.0001267534,0.000153425,0.00005705978],"category_scores_gemma":[0.0009203992,0.0001418095,0.00008370493,0.000069561,0.00006773655,0.0002091246,0.00004228209,0.00004769022,0.000001048818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003886017,"about_ca_system_score_gemma":0.00003774549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001745717,"about_ca_topic_score_gemma":0.000004950065,"domain_scores_codex":[0.9986393,0.0000376093,0.0005742915,0.0002791605,0.0002084132,0.0002612426],"domain_scores_gemma":[0.9986367,0.0003973104,0.0004509286,0.0002281709,0.0002187848,0.00006813011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001933921,0.0004042604,0.001113738,0.0003077562,0.00005372606,3.005896e-8,0.0003780789,0.000001097299,0.8887305,0.00006892533,0.000002031836,0.1087465],"study_design_scores_gemma":[0.0004387962,0.00004812453,0.03506674,0.00007506703,0.0001514116,0.000008330475,0.0002773745,0.0007143273,0.9624677,0.00003599367,0.0005292888,0.0001868421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923841,0.0005277867,0.006179171,0.00004453188,0.0001047727,0.0004568388,0.0001974682,0.000025324,0.00008003234],"genre_scores_gemma":[0.9737248,0.00006485227,0.02536282,0.000006911685,0.0001979167,0.0002039522,0.0003394621,0.00001956186,0.00007973192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1085597,"threshold_uncertainty_score":0.5782824,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2065599740","doi":"10.1021/jo0056287","title":"Evaluation of the Extent of Conjugation in Symmetrical and Asymmetrical Aryl-Substituted Acetophenone Azines Using Electrochemical Methods","year":2001,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Substituent; Acetophenone; Aryl; Protonation; Electrochemistry; Acetonitrile; Cyclic voltammetry; Dimethylformamide; Medicinal chemistry; Nitro; Ion; Crystallography; Photochemistry; Physical chemistry; Organic chemistry; Solvent; Electrode","retraction":null,"screen_n_in":null,"score":{"opus":0.06601627000910473,"gpt":0.3451744930935366,"spread":0.2791582230844318,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004483048,0.0001224337,0.0003317286,0.00004730458,0.00004061579,0.0000076763,0.0002853617,0.0001729933,0.0004905603],"category_scores_gemma":[0.00634671,0.000067138,0.0000968867,0.0007570218,0.0001527012,0.00005092497,0.00007605768,0.0003205062,1.855465e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002252576,"about_ca_system_score_gemma":0.0002037986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006668074,"about_ca_topic_score_gemma":8.567866e-7,"domain_scores_codex":[0.9979746,0.0002323099,0.0007455174,0.0001157916,0.0007921202,0.000139704],"domain_scores_gemma":[0.9975829,0.000781863,0.0007883487,0.0002042365,0.0005965311,0.0000461452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000124099,0.0001394718,0.003502587,0.00003464656,0.00005220549,4.447728e-7,0.00005258083,0.00004299724,0.9862021,0.000004026951,0.000003404487,0.009841423],"study_design_scores_gemma":[0.0009081321,0.00001938569,0.008890789,0.0001047251,0.0004028887,0.0002180866,0.0001688528,0.006053796,0.9823396,0.0008104122,0.000009872596,0.0000734737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961038,0.002082453,0.001195802,0.0002229379,0.00003071507,0.00006334026,0.000001055711,0.00000307436,0.0002968679],"genre_scores_gemma":[0.998485,0.0002803183,0.001092003,0.00001074727,0.0001149041,9.401983e-7,0.000001336123,0.000007699478,0.000007013898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009767949,"threshold_uncertainty_score":0.7598062,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2283631536","doi":"10.1039/c6ra02596j","title":"One-pot synthesis of highly functionalized pyrimido[1,2-b]indazoles via 6-endo-dig cyclization","year":2016,"lang":"en","type":"article","venue":"RSC Advances","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":52,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto Metropolitan University","funders":"Science and Engineering Research Board; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Dig; Ring (chemistry); Chemistry; Combinatorial chemistry; Computer science; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02953131996795849,"gpt":0.2676050733498444,"spread":0.2380737533818859,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001995781,0.0001500474,0.0002756731,0.00004439463,0.00007780267,0.00001105213,0.000161314,0.0001249236,0.003918483],"category_scores_gemma":[0.0008061808,0.00009462281,0.0001108226,0.00009888222,0.0001292247,0.0002370777,0.00003319471,0.00004115813,0.00007883248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007379923,"about_ca_system_score_gemma":0.00002559594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009256592,"about_ca_topic_score_gemma":0.000008589285,"domain_scores_codex":[0.9987223,0.00005295529,0.0003820236,0.000304055,0.0003492449,0.0001894249],"domain_scores_gemma":[0.9984162,0.0008832639,0.0002897403,0.0002226996,0.0001350975,0.00005299973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001233494,0.00009756382,0.003030004,0.00005180978,0.00003150948,2.719531e-7,0.000008126683,0.0000220036,0.6535061,0.0007184261,0.00002188962,0.3423889],"study_design_scores_gemma":[0.0004257683,0.00002950132,0.005716509,0.0002099322,0.00005793661,0.000001419698,0.00003873504,0.0000832438,0.9625249,0.006267275,0.02444885,0.0001959166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9600949,0.002670987,0.01119017,0.001078353,0.0002466881,0.0001592342,0.0001174665,0.0002433693,0.02419882],"genre_scores_gemma":[0.9974349,0.001003226,0.0007300557,0.00003967036,0.0002303633,0.00005661893,0.00001980895,0.00001435435,0.0004709872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.342193,"threshold_uncertainty_score":0.9969921,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1973237225","doi":"10.1016/j.jsbmb.2013.05.004","title":"Steroid-linked nitrogen mustards as potential anticancer therapeutics: A review","year":2013,"lang":"en","type":"review","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":51,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Université du Québec à Trois-Rivières","keywords":"Nitrogen mustard; Steroid; Chemistry; Nitrogen; Selectivity; Toxicity; Pharmacology; Biochemistry; Hormone; Biology; Organic chemistry; Medicine; Internal medicine; Chemotherapy","retraction":null,"screen_n_in":null,"score":{"opus":0.04171592107105342,"gpt":0.3537084488177067,"spread":0.3119925277466533,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001013901,0.0005289862,0.001681439,0.00004168499,0.0001002681,0.00004100454,0.0007550709,0.000716294,0.0007195573],"category_scores_gemma":[0.000184725,0.0002679364,0.0006889986,0.00009978282,0.000372004,0.00003084379,0.000207915,0.000720605,0.00002003205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006848742,"about_ca_system_score_gemma":0.0002490101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005753943,"about_ca_topic_score_gemma":1.210562e-7,"domain_scores_codex":[0.9973873,0.0004538259,0.001209182,0.0003348039,0.0002668074,0.0003480026],"domain_scores_gemma":[0.9973482,0.0002092616,0.001560802,0.0004843725,0.000260139,0.0001371599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005284608,0.00005942271,0.000001955449,0.01075797,0.0009424166,0.00002001174,0.000009415677,7.065584e-8,0.2601788,0.000005028512,0.0001800779,0.727792],"study_design_scores_gemma":[0.0008282288,0.000438448,7.504901e-7,0.02736593,0.008450009,0.003439931,0.0001027006,0.000004612607,0.08024731,0.001040171,0.8771406,0.0009412809],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008286655,0.9905388,0.00009129739,0.0003825994,0.00009610762,0.0002658016,0.00004384071,0.00001106085,0.0002838362],"genre_scores_gemma":[0.002718649,0.9955377,0.0001001664,0.0009889191,0.0004084517,0.00002518794,0.0000757548,0.00003353072,0.000111648],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8769606,"threshold_uncertainty_score":0.9999773,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988182123","doi":"10.1021/jo020750m","title":"Bis(pyridine)-Based Bromonium Ions. Molecular Structures of Bis(2,4,6-collidine)bromonium Perchlorate and Bis(pyridine)bromonium Triflate and the Mechanism of the Reactions of 1,2-Bis(2'-pyridylethynyl)benzenebrominum Triflate and Bis(pyridine)bromonium Triflate with Acceptor Olefins","year":2003,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Pyridine; Trifluoromethanesulfonate; Medicinal chemistry; Denticity; Nucleophile; Reaction mechanism; Perchlorate; Photochemistry; Crystal structure; Catalysis; Organic chemistry; Ion","retraction":null,"screen_n_in":null,"score":{"opus":0.01003689132240178,"gpt":0.2078034581065684,"spread":0.1977665667841666,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003338315,0.001120967,0.002016071,0.0001584143,0.0006012861,0.0001597294,0.001339105,0.0008414935,0.0008737657],"category_scores_gemma":[0.001546582,0.0006068496,0.000632541,0.001174477,0.001589768,0.0002860802,0.0003517769,0.001615769,0.000001004008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001968011,"about_ca_system_score_gemma":0.001181376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001053491,"about_ca_topic_score_gemma":0.00001816732,"domain_scores_codex":[0.9935672,0.0007602861,0.002563419,0.0008377701,0.001420025,0.0008512584],"domain_scores_gemma":[0.9918269,0.001422646,0.003871677,0.001452719,0.00101719,0.0004088697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002584524,0.0003037614,0.0003235169,0.000668487,0.0007508883,0.00001800131,0.0003350936,0.0004116812,0.9938752,0.0002740699,0.0002849217,0.0001698243],"study_design_scores_gemma":[0.007665572,0.0004276821,0.0007598564,0.000613834,0.001805265,0.0008303695,0.001402793,0.0007704269,0.9832749,0.0007672104,0.0009839198,0.0006981734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902513,0.00332344,0.0002083881,0.004115981,0.0002382937,0.0006717214,0.0001991645,0.00004994572,0.0009417556],"genre_scores_gemma":[0.9954314,0.003156708,0.0004222095,0.0002000587,0.0002148531,0.00002316802,0.00002102197,0.0001447006,0.0003858839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01060033,"threshold_uncertainty_score":0.9996383,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988897112","doi":"10.1016/j.yrtph.2007.10.018","title":"Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action","year":2007,"lang":"en","type":"article","venue":"Regulatory Toxicology and Pharmacology","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":50,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; Electric Power Research Institute","keywords":"Mechanism (biology); Metabolism; Mechanism of action; Naphthalene; Cytotoxicity; Action (physics); Relation (database); Chemistry; Physiology; Pharmacology; Biology; Cell biology; Biochemistry; In vitro; Computer science; Philosophy; Epistemology","retraction":null,"screen_n_in":null,"score":{"opus":0.02838965512337903,"gpt":0.3352783722099659,"spread":0.3068887170865869,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009925421,0.0001716731,0.0003978513,0.0001718133,0.00008175118,0.000002748053,0.00008914731,0.0004981207,0.001794196],"category_scores_gemma":[0.0000715022,0.0001560396,0.00003583279,0.0001522494,0.0002012952,0.00008545323,0.00007642167,0.0002309014,0.000004971512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006121062,"about_ca_system_score_gemma":0.0000337283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000121948,"about_ca_topic_score_gemma":0.00002033954,"domain_scores_codex":[0.9986123,0.0001843581,0.0004072525,0.0003993703,0.00008995162,0.0003068111],"domain_scores_gemma":[0.9992153,0.0003234714,0.0001821292,0.0001094406,0.00005054848,0.0001191307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003838946,0.0001263055,0.002001652,0.00005163983,0.00004065162,0.0000100854,0.00009704033,0.00003418639,0.9900663,0.003479497,0.00002535904,0.003683324],"study_design_scores_gemma":[0.0006350895,0.000109575,0.2253686,0.000006169919,0.00003893044,0.0000401761,0.00005450908,0.0002671214,0.7691875,0.002971459,0.001193602,0.0001272459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979951,0.0005529262,0.0002151277,0.0002468527,0.0002306462,0.0002125653,0.00001086035,0.00003027979,0.0005056527],"genre_scores_gemma":[0.9986781,0.0001798281,0.0005216748,0.0003321465,0.0001706095,0.00003166809,0.00001184714,0.00001007207,0.00006398863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.223367,"threshold_uncertainty_score":0.9991183,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2953010304","doi":"10.1021/ol048249z","title":"Synthesis of α-Fluorosulfonamides by Electrophilic Fluorination","year":2004,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":48,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Electrophile; Electrophilic fluorination; Sulfonamide; Group (periodic table); Primary (astronomy); Fluorine; Combinatorial chemistry; Halogenation; Organic chemistry; Medicinal chemistry; Catalysis","retraction":null,"screen_n_in":null,"score":{"opus":0.008888397908879117,"gpt":0.2109652004984202,"spread":0.2020768025895411,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001264983,0.0001029016,0.000144831,0.00002256405,0.0000407532,0.00001144811,0.0001415376,0.00008085644,0.001252575],"category_scores_gemma":[0.0003120391,0.00008346511,0.00005971175,0.0001061286,0.00005204236,0.0000568112,0.00001776819,0.00006722107,0.00004415741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001473718,"about_ca_system_score_gemma":0.00002258407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002267537,"about_ca_topic_score_gemma":0.000001437871,"domain_scores_codex":[0.9992385,0.00001730363,0.0002008109,0.0001879514,0.0001966856,0.000158754],"domain_scores_gemma":[0.999565,0.0001080138,0.0001053544,0.0001628863,0.00002886454,0.00002989971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009200189,0.00005543219,0.0002984404,0.00001905645,0.00001853795,7.38456e-7,0.00002097525,0.000005417141,0.9921854,0.0001234644,0.0002955215,0.006967877],"study_design_scores_gemma":[0.00018129,0.00001613647,0.0008722557,0.00002401405,0.00002303854,0.000003080614,0.00001651698,0.000007224342,0.9982014,0.0002956722,0.000256642,0.0001027638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995734,0.00009821627,0.0002734304,0.003315034,0.00002288185,0.00003351696,0.00000973113,0.00005194987,0.0004612231],"genre_scores_gemma":[0.9992802,0.00004400499,0.000190156,0.0003544246,0.00006874965,0.00001165263,0.00001699591,0.00001304988,0.00002077344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006865113,"threshold_uncertainty_score":0.9996604,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1970069945","doi":"10.1371/journal.pgen.1000284","title":"Chemical–Genetic Profiling of Imidazo[1,2-a]pyridines and -Pyrimidines Reveals Target Pathways Conserved between Yeast and Human Cells","year":2008,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; The Academy of Sciences for the Developing World","keywords":"Saccharomyces cerevisiae; Biology; Yeast; Pyrimidine; Biochemistry; Mutagenesis; Mechanism of action; DNA; Mitochondrion; DNA fragmentation; DNA damage; Cell biology; Mutant; In vitro; Apoptosis; Gene; Programmed cell death","retraction":null,"screen_n_in":null,"score":{"opus":0.0913608743036533,"gpt":0.252404454984638,"spread":0.1610435806809847,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001223453,0.0001922529,0.0003684718,0.00002914176,0.00009846691,0.00001428703,0.0001266985,0.0001851997,0.00009035994],"category_scores_gemma":[0.0001325265,0.000158931,0.00005015186,0.00006106443,0.0002532481,0.00001844425,0.000104926,0.00008900218,0.000002719447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001164786,"about_ca_system_score_gemma":0.00002479615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003512244,"about_ca_topic_score_gemma":3.9323e-7,"domain_scores_codex":[0.9987769,0.00003683716,0.000429432,0.0003253015,0.0002042694,0.0002272927],"domain_scores_gemma":[0.9992143,0.0001484439,0.0001879212,0.0002158335,0.0001195848,0.0001139151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007323732,0.00005100084,0.2036479,0.0001784131,0.00002934215,0.000001713504,0.00005821564,0.000008501225,0.7957975,0.000008008632,0.00002634436,0.0001857491],"study_design_scores_gemma":[0.0002771094,0.0000419465,0.0184963,0.00006383837,0.00007575609,0.000005849512,0.00004599376,0.0008456188,0.9794171,0.0005052861,0.00003038807,0.0001947844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980837,0.001237876,0.000005313768,0.00003363732,0.00001260857,0.0001347816,0.00009341136,0.00003660786,0.0003621178],"genre_scores_gemma":[0.9962399,0.0003276719,0.003127789,0.00001976541,0.000191999,0.0000149756,0.00003942537,0.00001973403,0.00001872141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1851516,"threshold_uncertainty_score":0.6481019,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2120703037","doi":"10.1375/1369052042335269","title":"Pharmacogenetics of Nicotine Metabolism in Twins: Methods and Procedures","year":2004,"lang":"en","type":"article","venue":"Twin Research","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"National Center for Research Resources; National Institute on Drug Abuse","keywords":"Zygosity; CYP2A6; Cotinine; Nicotine; Pharmacogenetics; Metabolite; Genotype; Drug metabolism; Medicine; Pharmacology; Pharmacokinetics; Twin study; Physiology; Metabolism; Drug; Genetics; Biology; Internal medicine; Heritability; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.1912067421631342,"gpt":0.5130750607108627,"spread":0.3218683185477286,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002295074,0.000068831,0.0001627743,0.00009117156,0.00003169871,0.00001286111,0.0001504652,0.00008878586,0.0005741722],"category_scores_gemma":[0.001543437,0.00005002562,0.00002672594,0.0002449958,0.0001502496,0.00002428913,0.0001026336,0.0002058622,0.000005486329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002668566,"about_ca_system_score_gemma":0.0001009095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001005223,"about_ca_topic_score_gemma":0.00001500409,"domain_scores_codex":[0.9988495,0.0001799016,0.0002158423,0.0002020097,0.0003240038,0.0002287031],"domain_scores_gemma":[0.9992938,0.0003614638,0.00003326708,0.0001296682,0.0001270801,0.00005472424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004788895,0.0001216738,0.003680847,0.0001215402,0.00001097714,0.000001089175,0.0001739615,0.00003193835,0.9571632,0.0003826801,0.00001804105,0.03824612],"study_design_scores_gemma":[0.0006333251,0.00002455198,0.02091074,0.00005437651,0.000007087932,0.000001916486,0.0001876821,0.0001509979,0.971534,0.005208299,0.001224505,0.00006249716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924558,0.003580824,0.00003711913,0.0002952275,0.0000103637,0.00009222921,0.000004065234,0.00001063294,0.003513713],"genre_scores_gemma":[0.9913384,0.0008214915,0.007598337,0.00001922667,0.00006813263,0.00002739799,0.000002767542,0.000007112984,0.0001170825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03818363,"threshold_uncertainty_score":0.6286783,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1968744900","doi":"10.1021/ol005519e","title":"Synthetic Studies of the Formation of Oxazoles and Isoxazoles from <i>N</i>-Acetoacetyl Derivatives: Scope and Limitations","year":2000,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Chemistry; Steric effects; Moiety; Scope (computer science); Combinatorial chemistry; Organic chemistry; Stereochemistry; Computational chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.04482459370831596,"gpt":0.2485142458664197,"spread":0.2036896521581037,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008882149,0.00007963942,0.0001505043,0.00001156188,0.00006772837,0.00000925051,0.00007429238,0.00003826747,0.0002190949],"category_scores_gemma":[0.0002534978,0.00004877187,0.00002660377,0.00006298799,0.0002392647,0.0000843259,0.00003376374,0.00004334271,0.000002075571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001360222,"about_ca_system_score_gemma":0.000007156144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008223827,"about_ca_topic_score_gemma":0.00001220675,"domain_scores_codex":[0.9994653,0.00004141179,0.0002064432,0.0001140068,0.0001040737,0.00006878449],"domain_scores_gemma":[0.9993137,0.0003970893,0.0001175978,0.000128348,0.00002902128,0.00001421743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009597418,0.00001682748,0.0007992613,0.00004919125,0.00003297146,5.380228e-8,0.001465694,0.000004673534,0.9791192,0.00001534097,0.00009006402,0.01839706],"study_design_scores_gemma":[0.0002254219,0.00001163639,0.013008,0.0001696048,0.00005719566,0.000001522531,0.002073153,0.00009212165,0.9839729,0.0001810048,0.0001366169,0.00007078655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954646,0.001383508,0.00002706787,0.002796704,0.0000110027,0.00005629592,0.00001522546,0.00001000457,0.0002356383],"genre_scores_gemma":[0.9975422,0.001899008,0.0002171693,0.0002995136,0.00001813831,0.000005073,0.000004345537,0.000005182068,0.000009361155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01832628,"threshold_uncertainty_score":0.2398936,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2952909594","doi":"10.1021/ol101454x","title":"Practical Synthesis of Quinoxalinones via Palladium-Catalyzed Intramolecular N-Arylations","year":2010,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Intramolecular force; Palladium; Chemistry; Yield (engineering); Catalysis; Bicyclic molecule; Microwave irradiation; Combinatorial chemistry; Organic chemistry; Materials science","retraction":null,"screen_n_in":null,"score":{"opus":0.01751641830651879,"gpt":0.2601327363314102,"spread":0.2426163180248914,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002468859,0.0001306509,0.0001961971,0.00003289723,0.0000611001,0.00002074058,0.0001659121,0.0001697769,0.006809582],"category_scores_gemma":[0.001388904,0.0001037138,0.00009530356,0.000112622,0.0001295823,0.00007178932,0.00004160358,0.0002204854,0.0001163639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002247204,"about_ca_system_score_gemma":0.00004217045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001943346,"about_ca_topic_score_gemma":0.000012806,"domain_scores_codex":[0.9990159,0.00003910119,0.0002909919,0.0002401533,0.000230061,0.0001838215],"domain_scores_gemma":[0.9988532,0.0005207824,0.0001542218,0.0003480144,0.00005375786,0.00007002689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001453919,0.00008562652,0.001498672,0.00001978443,0.00004423262,0.000005395445,0.00002448869,6.861898e-7,0.9954699,0.0001528244,0.0002689782,0.002414828],"study_design_scores_gemma":[0.0001369626,0.000005498111,0.002438175,0.00001183488,0.00008379615,0.0000196233,0.00002424984,0.0001643193,0.9965602,0.00008414676,0.0003305518,0.0001405998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889661,0.000007738305,0.001921331,0.008327087,0.00009509569,0.00005299936,0.00000862159,0.00005636032,0.0005646825],"genre_scores_gemma":[0.9964811,0.000006581854,0.002916915,0.0003563865,0.000176406,0.00001459091,0.00002297536,0.00001770845,0.000007394315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007970701,"threshold_uncertainty_score":0.9940983,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3016150871","doi":"10.1016/j.cplett.2020.137469","title":"Gas-phase UV absorption spectra of pyrazine, pyrimidine and pyridazine","year":2020,"lang":"en","type":"article","venue":"Chemical Physics Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":42,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Providence Health Care","keywords":"Pyridazine; Pyrazine; Chemistry; Absorption spectroscopy; Monochromator; Pyrimidine; Absorption (acoustics); Photodissociation; Analytical Chemistry (journal); Photochemistry; Spectral line; Disproportionation; Wavelength; Materials science; Organic chemistry; Optics; Stereochemistry; Catalysis","retraction":null,"screen_n_in":null,"score":{"opus":0.03528512478180896,"gpt":0.2629518455612624,"spread":0.2276667207794535,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000051,0.0001445919,0.0002376055,0.000006960925,0.00001890069,0.00001239807,0.0001097762,0.00007433985,0.000302897],"category_scores_gemma":[0.0001149552,0.0001199241,0.0000867767,0.00009467187,0.0001427591,0.00005664467,0.00004770105,0.0001420056,0.00001821499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002136685,"about_ca_system_score_gemma":0.000006488996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002568828,"about_ca_topic_score_gemma":3.248214e-8,"domain_scores_codex":[0.9991501,0.000007883705,0.0002327852,0.0002772691,0.0001768809,0.000155093],"domain_scores_gemma":[0.99954,0.00008406196,0.0001119659,0.0001298506,0.00003048627,0.0001036191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008370775,0.0001030179,0.00017614,0.00009651588,0.00002118038,0.00000162607,0.00005187638,0.000007702432,0.9866793,0.0001393606,0.001157507,0.01148209],"study_design_scores_gemma":[0.0007352837,0.00002861927,0.0001067068,0.00002335028,0.00003684005,9.589412e-7,0.00001386543,0.0020043,0.9960747,0.0005324566,0.0002981212,0.000144835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921142,0.00004825218,0.0004901156,0.006207834,0.00001336284,0.00004617381,0.00002101679,0.00005519058,0.00100386],"genre_scores_gemma":[0.9974406,0.0000237512,0.000350671,0.001500515,0.0005788389,0.00000585907,0.00008256865,0.00001366995,0.000003559227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01133725,"threshold_uncertainty_score":0.4890361,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2045687388","doi":"10.1039/c3ob41539b","title":"Synthesis and anti-toxoplasmosis activity of 4-arylquinoline-2-carboxylate derivatives","year":2013,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":42,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Stanley Medical Research Institute","keywords":"Chemistry; Triflic acid; Trifluoromethanesulfonate; Antiprotozoal; Quinoline; Brønsted–Lowry acid–base theory; Toxoplasma gondii; Catalysis; Lewis acids and bases; Prenylation; Carboxylate; Combinatorial chemistry; Organic chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01258039376027466,"gpt":0.2243960942267866,"spread":0.2118157004665119,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001255759,0.0002497605,0.000355374,0.00001969554,0.00006681745,0.00003803855,0.0002148666,0.0002872161,0.006291547],"category_scores_gemma":[0.0005285667,0.0002081491,0.000109279,0.0001665356,0.0002058265,0.0000856616,0.0001413047,0.000129728,0.00002661679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003672573,"about_ca_system_score_gemma":0.00004160111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003854573,"about_ca_topic_score_gemma":4.031886e-7,"domain_scores_codex":[0.9987552,0.0000317344,0.0002828601,0.0004341528,0.0002320118,0.0002640972],"domain_scores_gemma":[0.9990274,0.0001581382,0.0002137395,0.0003799917,0.0001070179,0.0001137246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001004365,0.000109023,0.002072841,0.0002271562,0.00008803439,0.000002928317,0.00002386259,6.958663e-8,0.9893824,0.000002345236,0.00002400104,0.008057263],"study_design_scores_gemma":[0.0001879222,0.000008691392,0.004865654,0.00008532024,0.00006267891,0.00001526417,0.00006791688,0.0002065632,0.994106,0.00007813026,0.00006729281,0.0002485626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954032,0.0003021587,0.000888571,0.0002916328,0.00001262452,0.0000732695,0.00001717068,0.00006758357,0.002943756],"genre_scores_gemma":[0.999272,0.0001973915,0.0002779662,0.00003076698,0.00004586868,0.00003396054,0.00001133826,0.00002683936,0.0001038901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0078087,"threshold_uncertainty_score":0.9946169,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2939434783","doi":"10.1038/s41598-019-42816-4","title":"Examination of novel 4-aminoquinoline derivatives designed and synthesized by a hybrid pharmacophore approach to enhance their anticancer activities","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":42,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa; Laurentian University; Health Sciences North","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Ontario","keywords":"Pharmacophore; Cancer cell; Cancer; Cytotoxicity; Breast cancer; Cancer research; Chemistry; Cell cycle; Pharmacology; Medicine; Biochemistry; In vitro; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02847618399306277,"gpt":0.2825807442693987,"spread":0.2541045602763359,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001184355,0.0001496162,0.0002712798,0.00006242157,0.00008505116,0.00007409843,0.0001041957,0.00005399553,0.0002945324],"category_scores_gemma":[0.0002951976,0.0001081638,0.00004924672,0.0001603528,0.000199929,0.0001370567,0.00005989369,0.00005542033,0.000001910373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003474803,"about_ca_system_score_gemma":0.00004433924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005426438,"about_ca_topic_score_gemma":2.497153e-7,"domain_scores_codex":[0.9984002,0.00004440261,0.0003675159,0.0006473741,0.0003501757,0.0001903797],"domain_scores_gemma":[0.998952,0.0001973494,0.0003292614,0.0003452844,0.0001135829,0.00006255349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002980664,0.0002029714,0.000485629,0.0000850623,0.00001931545,7.535847e-7,0.0003396977,0.000009744514,0.9706417,0.00000546685,0.0002134419,0.02796636],"study_design_scores_gemma":[0.0001195637,0.00002027009,0.001240757,0.00006830967,0.00001409147,0.00001563381,0.0003551987,0.001388379,0.9958739,0.00005441919,0.0007044131,0.0001450612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942723,0.0002043154,0.001748732,0.0000279692,0.0002532036,0.0002672244,0.00002177281,0.00003121681,0.0031733],"genre_scores_gemma":[0.9970865,0.00001486705,0.00128027,0.00001738795,0.00002750434,0.00005165754,0.00004911447,0.00001010958,0.001462588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0278213,"threshold_uncertainty_score":0.4410793,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2083974470","doi":"10.1016/s0960-894x(00)00400-5","title":"Synthesis and 5-Hydroxytryptamine (5-HT) activity of 2,3,4,4a-Tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-Hexahydro-1H-pyrazino[1,2-a]quinoxalines","year":2000,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":40,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Stereochemistry; Chemical synthesis; In vitro; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01364525367809682,"gpt":0.2265792113874799,"spread":0.2129339577093831,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008015022,0.0009418754,0.001288577,0.0001036676,0.0002999779,0.00008699909,0.0006318523,0.0007585638,0.008839074],"category_scores_gemma":[0.0009981317,0.0008006322,0.0002712597,0.0004053597,0.001393534,0.0002590707,0.0002004312,0.0006708814,0.00004338683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611091,"about_ca_system_score_gemma":0.0001107448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001920054,"about_ca_topic_score_gemma":0.000008891516,"domain_scores_codex":[0.9953267,0.0001167799,0.001125108,0.001427421,0.001055683,0.0009483068],"domain_scores_gemma":[0.9970596,0.000762481,0.0005728698,0.0009194344,0.0001342251,0.0005513779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003135174,0.0002737829,0.004525199,0.0008314783,0.0001522741,0.00005512479,0.0001681479,0.000006166371,0.9541516,0.000005107273,0.0006810494,0.03883652],"study_design_scores_gemma":[0.001329372,0.00007405398,0.01057525,0.0005346811,0.0004790659,0.000287844,0.0002499081,0.0005956581,0.9825374,0.00006670104,0.002361891,0.0009081051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914836,0.002130518,0.00001960459,0.0036453,0.0001112407,0.0002153357,0.0001241472,0.0002145413,0.002055772],"genre_scores_gemma":[0.9960763,0.001504545,0.0001865823,0.0006199434,0.001068623,0.00005729356,0.00007244971,0.00009443155,0.0003198347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03792842,"threshold_uncertainty_score":0.9994445,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2333517888","doi":"10.1097/00001813-200301000-00004","title":"In vitro studies on the lymphoma growth-inhibitory activity of sulfasalazine","year":2003,"lang":"en","type":"article","venue":"Anti-Cancer Drugs","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Sulfasalazine; In vitro; Inhibitory postsynaptic potential; Lymphoma; Cancer research; Pharmacology; Chemistry; Medicine; Immunology; Internal medicine; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.04701858184242599,"gpt":0.3052550081109162,"spread":0.2582364262684902,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004712766,0.0001257435,0.0002502213,0.00002530676,0.00005396318,0.000006535292,0.0001109245,0.00007814656,0.0003592892],"category_scores_gemma":[0.0004361456,0.00007312679,0.00007947795,0.0001308272,0.0001221879,0.00005274361,0.00002644741,0.00007699326,0.00001419535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009499241,"about_ca_system_score_gemma":0.00004635222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006853328,"about_ca_topic_score_gemma":0.000007730823,"domain_scores_codex":[0.9991074,0.0001020848,0.0002023818,0.0002162743,0.0002098442,0.0001620761],"domain_scores_gemma":[0.9990939,0.0004801741,0.0001422599,0.0001903256,0.00007430201,0.00001897632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007422797,0.0002102674,0.002089498,0.00004678413,0.00004725346,9.581798e-7,0.0002356665,0.000004804809,0.9900983,0.0006123608,0.0005393869,0.006040481],"study_design_scores_gemma":[0.0003795928,0.00001271336,0.003091109,0.00005649854,0.00001334488,2.857619e-7,0.0003865045,0.00002755681,0.9946653,0.0004488463,0.0008212241,0.00009706359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991242,0.0006018227,6.190023e-7,0.001005052,0.0001397593,0.00006106366,0.00001184266,0.00001453481,0.006923302],"genre_scores_gemma":[0.9985268,0.0006387436,0.00001114746,0.0002838904,0.000100985,0.00004573939,0.00000116925,0.000008098769,0.0003834627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00728476,"threshold_uncertainty_score":0.3933965,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2950414791","doi":"10.1055/s-2006-948176","title":"A Facile Synthesis of Fluorophores Based on 5-Phenylethynyluracils","year":2006,"lang":"en","type":"article","venue":"Synlett","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Sonogashira coupling; Yield (engineering); Combinatorial chemistry; Fluorescence; Oligonucleotide; Nucleic acid; Uracil; Peptide nucleic acid; Coupling reaction; Catalysis; Organic chemistry; Palladium","retraction":null,"screen_n_in":null,"score":{"opus":0.01404211910633125,"gpt":0.2296420167229749,"spread":0.2155998976166437,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002228412,0.0001368308,0.0002198466,0.00003928023,0.00004786198,0.00001304901,0.0001514305,0.0001379961,0.006087166],"category_scores_gemma":[0.0005176816,0.00009837986,0.0001326499,0.00008240301,0.00007424982,0.00002125175,0.00001570842,0.00007565383,0.0001350952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003605356,"about_ca_system_score_gemma":0.00002436419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009781087,"about_ca_topic_score_gemma":0.000004281915,"domain_scores_codex":[0.9989555,0.00004700837,0.0002725861,0.0002339399,0.0003087156,0.0001822116],"domain_scores_gemma":[0.9988286,0.0006760337,0.0001193727,0.0002919036,0.00005257093,0.00003153564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000933235,0.0002617736,0.003140129,0.00008281212,0.00001392434,0.000004766029,0.000007453139,0.0003847968,0.9573534,0.0002756705,0.002721068,0.03566087],"study_design_scores_gemma":[0.0001643535,0.00003692088,0.004173669,0.00008705218,0.0000253873,6.992722e-7,0.00002342751,0.002213,0.986678,0.000439745,0.006002976,0.0001547772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8767819,0.0001101912,0.0001394884,0.0005201363,0.00003707551,0.00007092086,0.0001075038,0.00008712339,0.1221457],"genre_scores_gemma":[0.9987297,0.000003988131,0.0005450702,0.0001033451,0.0001201883,0.0000416374,0.00002185482,0.00001029777,0.0004239399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1219478,"threshold_uncertainty_score":0.9948214,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2131650698","doi":"10.1039/b909153j","title":"Synthesis and DNA-binding affinity studies of glycosylated intercalators designed as functional mimics of the anthracycline antibiotics","year":2009,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":38,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre","keywords":"Chemistry; Linker; DNA; Aminosugar; Doxorubicin; Anthracycline; Stereochemistry; Moiety; Daunorubicin; Biochemistry; Combinatorial chemistry; Cancer; Chemotherapy; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.02787023561749149,"gpt":0.2708432407384606,"spread":0.2429730051209691,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002873448,0.0002046162,0.0003518502,0.00001905145,0.0000901655,0.00001234493,0.0002145827,0.0002455275,0.0005976595],"category_scores_gemma":[0.001912781,0.0001415997,0.000140824,0.0002402279,0.0002842139,0.00003005111,0.0001111681,0.0001295625,0.000002519475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005917401,"about_ca_system_score_gemma":0.00006561029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002060468,"about_ca_topic_score_gemma":3.629661e-7,"domain_scores_codex":[0.9987544,0.00004122666,0.0004497179,0.0002972934,0.0002823914,0.0001749702],"domain_scores_gemma":[0.9988574,0.0002509386,0.0003440615,0.0003284077,0.0001647948,0.00005443359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006329333,0.0001701289,0.0008461216,0.000159817,0.0001347977,0.00000286612,0.00003927281,4.248795e-7,0.9971691,0.00000969175,0.00001979237,0.001384722],"study_design_scores_gemma":[0.0002536327,0.00003006566,0.001038867,0.0002455941,0.000162241,0.00002335164,0.0004107981,0.00006377841,0.9974378,0.000166289,0.00001301223,0.0001546172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983655,0.0004540389,0.0003653541,0.0002638407,0.00003564959,0.00005260357,0.00002155535,0.00002834527,0.0004131642],"genre_scores_gemma":[0.9994726,0.0002092427,0.0001648417,0.00003761446,0.00003828869,5.704483e-7,0.00001344843,0.0000128986,0.00005054038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001625436,"threshold_uncertainty_score":0.6543952,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2023049214","doi":"10.1021/jf103194k","title":"Dimerization of Azomethine Ylides: An Alternate Route to Pyrazine Formation in the Maillard Reaction","year":2010,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":38,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Maillard reaction; Pyrazine; Chemistry; Azomethine ylide; Organic chemistry; Combinatorial chemistry; Cycloaddition; Catalysis","retraction":null,"screen_n_in":null,"score":{"opus":0.01921045376535226,"gpt":0.2478497610280635,"spread":0.2286393072627112,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003178412,0.00008634328,0.0001452324,0.00001595649,0.00003319206,0.00002947132,0.0001329119,0.0001079299,0.00004261766],"category_scores_gemma":[0.0001679974,0.00003960238,0.00005253092,0.0001073096,0.00001922171,0.0002300006,0.00001534489,0.0002269276,4.48265e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001772562,"about_ca_system_score_gemma":0.000006069904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006570485,"about_ca_topic_score_gemma":0.00001052853,"domain_scores_codex":[0.9992335,0.00001470889,0.0003739397,0.00007826045,0.0002195854,0.00007995062],"domain_scores_gemma":[0.9993017,0.00004800323,0.0003645351,0.00007296324,0.0001610469,0.0000517152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003248615,0.00005620211,0.0008351301,0.00003994873,0.0000108601,4.893876e-7,0.0002184524,0.00001767639,0.9946755,0.00001244482,0.00002010814,0.004080715],"study_design_scores_gemma":[0.0002655181,0.0001080804,0.103496,0.00005353284,0.00002594952,0.0002381435,0.0009219865,0.00003134073,0.8944097,0.0001784856,0.0001959066,0.0000753959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985612,0.00004008087,0.00001214647,0.0006509784,0.00004105575,0.00003158949,0.000007056374,0.000004589703,0.0006512858],"genre_scores_gemma":[0.9993478,0.00006452769,0.0002061418,0.00003392014,0.0002835245,0.000002301867,0.00002941163,0.0000022481,0.00003009877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1026609,"threshold_uncertainty_score":0.1614938,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2081016768","doi":"10.1016/j.bmcl.2008.12.089","title":"Syntheses and potential anti-prostate cancer activities of ionone-based chalcones","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":37,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Jewish General Hospital; McGill University","funders":"","keywords":"LNCaP; Chemistry; Chalcone; Transactivation; Prostate cancer; Androgen receptor; Ionone; Antagonist; In vitro; Pharmacology; Prostate; Androgen Receptor Antagonists; Cancer research; Stereochemistry; Receptor; Biochemistry; Cancer; Internal medicine; Biology; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.02677286193921963,"gpt":0.2387827053106248,"spread":0.2120098433714052,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001342962,0.0002112044,0.0003339796,0.0000224591,0.0001102555,0.0000092428,0.0001474231,0.0001375777,0.002045006],"category_scores_gemma":[0.0001858609,0.0001631801,0.00007630281,0.00007831343,0.0005392302,0.00004980415,0.00003744318,0.0001432167,0.000002143639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005011461,"about_ca_system_score_gemma":0.00008802614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007026552,"about_ca_topic_score_gemma":6.970474e-7,"domain_scores_codex":[0.9987779,0.00002028415,0.0002883379,0.0003267014,0.0003424388,0.0002443846],"domain_scores_gemma":[0.9992988,0.0001669809,0.0002024532,0.0001929269,0.00004389281,0.00009496002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000746284,0.00005208817,0.00914017,0.0002764497,0.00004827644,0.00002480594,0.00009867437,0.000005507825,0.9882446,6.156944e-7,0.0001678267,0.001866384],"study_design_scores_gemma":[0.0004239553,0.00001180057,0.006128721,0.0002236902,0.00007386546,0.0000574114,0.0003101693,0.00008698997,0.992287,0.000003177576,0.0002004329,0.0001927502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956182,0.0008720975,0.00002780593,0.002971092,0.00005778184,0.0000465208,0.00004737198,0.00005080315,0.0003082824],"genre_scores_gemma":[0.9986204,0.0005333929,0.00005363212,0.0003160593,0.0003530055,0.00001634708,0.00002124839,0.00001708462,0.00006883019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004042464,"threshold_uncertainty_score":0.9988673,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1977620138","doi":"10.1016/j.bmc.2004.05.008","title":"Synthesis and biological evaluation of 1,4-dihydropyridine calcium channel modulators having a diazen-1-ium-1,2-diolate nitric oxide donor moiety for the potential treatment of congestive heart failure","year":2004,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":36,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Substituent; Moiety; Aryl; Stereochemistry; Calcium channel; Context (archaeology); Medicinal chemistry; Calcium; Organic chemistry; Alkyl","retraction":null,"screen_n_in":null,"score":{"opus":0.05380220856828151,"gpt":0.2843832076593303,"spread":0.2305809990910488,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008660285,0.0003102047,0.0005661517,0.00002804762,0.0001354859,0.00001183584,0.0001855659,0.0003600054,0.0003286531],"category_scores_gemma":[0.001410691,0.0001809067,0.0002142428,0.0001612823,0.0003482409,0.00003896207,0.00005184197,0.0001154211,0.000001171906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002688692,"about_ca_system_score_gemma":0.0001861425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001526204,"about_ca_topic_score_gemma":0.000002495069,"domain_scores_codex":[0.998139,0.00005662605,0.0005469781,0.0004797621,0.0004805934,0.0002970605],"domain_scores_gemma":[0.9982606,0.0006008358,0.0003637379,0.0003156743,0.0003351185,0.0001240663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001892279,0.0002420019,0.001442936,0.0001235144,0.0001805041,0.000001043019,0.00006791743,0.0001848584,0.9947777,0.000005725018,0.00001565136,0.002768969],"study_design_scores_gemma":[0.001766156,0.000151371,0.01377522,0.0001649296,0.0007898983,0.0000403195,0.000773731,0.00484453,0.9771777,0.0002700994,0.000046958,0.0001991301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958038,0.002397813,0.000371875,0.0008179208,0.00003710328,0.0003877082,0.0001099133,0.00003375396,0.00004007735],"genre_scores_gemma":[0.9989815,0.0002501788,0.0001962058,0.00002010231,0.0003107949,0.0001604473,0.00004850046,0.00001956066,0.00001274492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01759999,"threshold_uncertainty_score":0.7377161,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2097851755","doi":"10.1038/clpt.2013.114","title":"CYP2A6 Genotype but not Age Determines Cotinine Half-Life in Infants and Children","year":2013,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; National Institute on Drug Abuse; U.S. Public Health Service","keywords":"CYP2A6; Cotinine; Genotype; Medicine; Pediatrics; Biology; Genetics; Nicotine; Internal medicine; Gene; Metabolism","retraction":null,"screen_n_in":null,"score":{"opus":0.1188213191833654,"gpt":0.4010143497930177,"spread":0.2821930306096523,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005175287,0.0002193278,0.0004672625,0.00003684593,0.00006632042,0.00002958154,0.0002643477,0.0004455216,0.003016072],"category_scores_gemma":[0.0001717223,0.0001649436,0.00009757186,0.00007713278,0.0004125228,0.00006465186,0.0001337032,0.0004580978,0.0001538285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001971165,"about_ca_system_score_gemma":0.00004826468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005067993,"about_ca_topic_score_gemma":0.00001378668,"domain_scores_codex":[0.9981005,0.0002220675,0.0007666839,0.0004344653,0.0001307998,0.000345536],"domain_scores_gemma":[0.9980634,0.001297896,0.0002046306,0.0001900699,0.00007467894,0.0001693596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004088846,0.0006228976,0.4971032,0.00001934214,0.0003424853,0.0000146468,0.00006676363,0.000006524946,0.396509,0.000005469318,0.001282341,0.1036185],"study_design_scores_gemma":[0.00348402,0.0002010401,0.9534278,0.00002112716,0.0003271097,0.00001192951,0.00002910141,0.003640543,0.03403873,0.0002802564,0.004140073,0.000398265],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951091,0.0005337928,0.000005914252,0.003286501,0.0003131526,0.0002362317,0.00001149524,0.00006142913,0.0004424234],"genre_scores_gemma":[0.966805,0.001337321,0.0002080565,0.03069532,0.0006540811,0.00004750005,0.00002410168,0.00001998037,0.0002086368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4563246,"threshold_uncertainty_score":0.9978953,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1970649495","doi":"10.1081/ncn-100001435","title":"SYNTHESIS OF 1-(2-DEOXY-β-<scp>D</scp>- RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENE THYMIDINE MIMICS,<sup>*</sup>SOME RELATED α-ANOMERS, AND THEIR EVALUATION AS ANTIVIRAL AND ANTICANCER AGENTS","year":2001,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Anomer; Chemistry; Stereochemistry; Cytotoxicity; Nucleoside; Thymidine; Biochemistry; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.02210800549271585,"gpt":0.2548201975568576,"spread":0.2327121920641418,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001641323,0.0008907506,0.001276432,0.0003050487,0.0004742171,0.0002180587,0.0005985451,0.0007264329,0.001787388],"category_scores_gemma":[0.003299828,0.0007306437,0.0003516485,0.0005565241,0.0009792052,0.0009346056,0.0003541835,0.0004932989,0.000111114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000210527,"about_ca_system_score_gemma":0.0001075976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00017659,"about_ca_topic_score_gemma":0.00001064665,"domain_scores_codex":[0.9949989,0.0003547384,0.001408215,0.001359878,0.0009343286,0.0009439852],"domain_scores_gemma":[0.9960285,0.001559487,0.0007582272,0.0008903369,0.0004040471,0.0003593661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000353028,0.0008182556,0.07006162,0.0004267162,0.001039709,0.0000462223,0.002667766,0.0003097323,0.7288651,0.002774896,0.0007222269,0.1919147],"study_design_scores_gemma":[0.006275499,0.0006950137,0.1975542,0.001995488,0.002411006,0.0004064717,0.01059815,0.1321079,0.6141857,0.01782408,0.01390807,0.002038361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860157,0.00233329,0.00001061184,0.0005333701,0.0001488324,0.0005841026,0.0001339972,0.0003007588,0.009939303],"genre_scores_gemma":[0.9933962,0.004998403,0.0005758543,0.0002866398,0.0002349434,0.00006673262,0.00008599665,0.0001452404,0.0002100227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1898763,"threshold_uncertainty_score":0.9995145,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012212383","doi":"10.1016/j.ijms.2003.08.012","title":"A tandem mass spectrometric study of the N-oxides, quinoline N-oxide, carbadox, and olaquindox, carried out at high mass accuracy using electrospray ionization","year":2003,"lang":"en","type":"article","venue":"International Journal of Mass Spectrometry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Trent University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Mass spectrometry; Mass spectrum; Collision-induced dissociation; Fragmentation (computing); Tandem mass spectrometry; Analytical Chemistry (journal); Electrospray ionization; Ion; Electrospray; Quinoline; Protonation; Oxide; Atmospheric-pressure chemical ionization; Molecule; Ionization; Chemical ionization; Chromatography; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02752710892573556,"gpt":0.2883080755056,"spread":0.2607809665798644,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001069193,0.0003071062,0.0005523154,0.0005699437,0.0001415342,0.0001133929,0.0006829703,0.0001923399,0.000806621],"category_scores_gemma":[0.002766497,0.0002129284,0.0002421039,0.0007329113,0.00009050766,0.0002447423,0.00009382936,0.0004766944,0.000002740919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001033606,"about_ca_system_score_gemma":0.0001684233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003710303,"about_ca_topic_score_gemma":0.00001820179,"domain_scores_codex":[0.9963055,0.0002653103,0.001161995,0.0003577758,0.001570038,0.0003394186],"domain_scores_gemma":[0.996542,0.0005376514,0.001692587,0.0003048397,0.0008020345,0.0001209013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001615026,0.0002611904,0.2211259,0.00001212378,0.0004199399,0.00002547871,0.00007872692,0.0001517006,0.7771378,0.0004003223,0.0000199877,0.0002052574],"study_design_scores_gemma":[0.003887473,0.0005337829,0.1032412,0.0001378173,0.0003503928,0.0003142804,0.0008177912,0.0004348445,0.8859305,0.003738337,0.0002235388,0.0003900976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948776,0.0009851252,0.00247374,0.0001688477,0.0005455667,0.0001803786,0.00002036003,0.00001722524,0.0007311591],"genre_scores_gemma":[0.9954963,0.0002287991,0.003640648,0.00005978605,0.0003854699,0.000003985647,0.000006450417,0.00003009755,0.000148414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1178848,"threshold_uncertainty_score":0.8831935,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2013063519","doi":"10.1016/j.molstruc.2006.09.032","title":"Interaction of zanamivir with DNA and RNA: Models for drug–DNA and drug–RNA bindings","year":2006,"lang":"en","type":"article","venue":"Journal of Molecular Structure","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Iran National Science Foundation","keywords":"Zanamivir; Chemistry; RNA; DNA; Neuraminidase; Base pair; Binding constant; Polynucleotide; Stereochemistry; Enzyme; Binding site; Molecular biology; Biochemistry; Biology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.008237405808863665,"gpt":0.2319622483550877,"spread":0.223724842546224,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001472544,0.0001206019,0.0002340695,0.00005546683,0.00004059595,0.00003022661,0.00007057995,0.00009097528,0.00003397361],"category_scores_gemma":[0.00004617314,0.00007588247,0.00007011952,0.00004657273,0.00004973466,0.0001149875,0.00001728957,0.0001411517,3.573297e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002655183,"about_ca_system_score_gemma":0.00002153211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001178739,"about_ca_topic_score_gemma":0.000006771694,"domain_scores_codex":[0.999252,0.00002220642,0.0002905182,0.0001268205,0.0002072908,0.0001011228],"domain_scores_gemma":[0.9991935,0.00006656899,0.0004675711,0.00007399103,0.0001550539,0.00004329839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001860024,0.00001766963,0.00028627,0.00006620821,0.00005819514,0.000006410939,0.00008743128,0.0004186887,0.9911581,0.0001450561,0.0001294034,0.007440575],"study_design_scores_gemma":[0.0008417483,0.00008955973,0.0009533252,0.0001424098,0.0001089221,0.0001170599,0.000251782,0.001466368,0.9861626,0.009530007,0.000220422,0.0001157987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977815,0.0004400132,0.00102129,0.0002435419,0.00004158764,0.00005719916,0.00001788145,0.000003942079,0.0003930239],"genre_scores_gemma":[0.9982173,0.00003452909,0.001536876,0.00003530643,0.0001174897,0.000001111938,0.000006561992,0.00001062907,0.00004021408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009384951,"threshold_uncertainty_score":0.3094397,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2180171621","doi":"10.1039/c5ob01650a","title":"Synthesis and anti-cancer activity of 1,4-disubstituted imidazo[4,5-c]quinolines","year":2015,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":31,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Innovation Initiatives Ontario North; Nipissing University","funders":"","keywords":"Chemistry; Quinoline; Imidazole; Isocyanide; Combinatorial chemistry; Ring (chemistry); Catalysis; Stereochemistry; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03437288535784227,"gpt":0.2745903807481297,"spread":0.2402174953902875,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001925918,0.0002152043,0.0003285233,0.00001687578,0.00004360405,0.00002412536,0.0002035566,0.0002720981,0.001566135],"category_scores_gemma":[0.0006911017,0.0001788532,0.00008620631,0.0001627712,0.0001851045,0.00005648974,0.0001146357,0.0001063191,0.000008797262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006192523,"about_ca_system_score_gemma":0.0001170395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003433297,"about_ca_topic_score_gemma":0.000001318821,"domain_scores_codex":[0.9988429,0.00002407539,0.0002422898,0.0003873311,0.0002812078,0.0002221786],"domain_scores_gemma":[0.9990934,0.0000630916,0.0001909503,0.0003410986,0.0001534946,0.0001580008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003722184,0.0001238605,0.001918584,0.0001940698,0.00007027729,0.000005703846,0.00002068078,5.59027e-7,0.9929652,0.000002716351,0.00004653975,0.004614613],"study_design_scores_gemma":[0.0003319687,0.000005602157,0.0005450495,0.00007793758,0.00008896817,0.00001396096,0.00006512945,0.0002054095,0.9980826,0.00003107928,0.0003258166,0.0002265087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960293,0.000938481,0.0007673369,0.0002126637,0.00002907883,0.0000425399,0.00004413412,0.00006894834,0.001867545],"genre_scores_gemma":[0.9993919,0.0002126118,0.0001016948,0.00002093839,0.0001122613,0.00001886473,0.00001766516,0.00002187247,0.0001021572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005117395,"threshold_uncertainty_score":0.9993466,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2088396801","doi":"10.1002/jhet.5570440610","title":"Synthesis of novel coumarin and benzocoumarin derivatives and their biological and photophysical studies","year":2007,"lang":"en","type":"article","venue":"Journal of Heterocyclic Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke; University of Winnipeg; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Chemistry; Coumarin; Nucleophile; Ring (chemistry); Methylene; Fluorescence; Proton NMR; Medicinal chemistry; Nucleophilic substitution; Stereochemistry; Organic chemistry; Catalysis","retraction":null,"screen_n_in":null,"score":{"opus":0.06500361640655801,"gpt":0.3098766330391521,"spread":0.2448730166325941,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003946333,0.0001818519,0.0005161719,0.00002191291,0.00005634149,0.00001655074,0.00009426215,0.0001653577,0.00006410307],"category_scores_gemma":[0.0008220643,0.000108183,0.00008405218,0.000036952,0.0004299304,0.00005777129,0.0001239221,0.0001842002,9.349392e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002833637,"about_ca_system_score_gemma":0.000007398816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000236443,"about_ca_topic_score_gemma":7.301243e-7,"domain_scores_codex":[0.9989691,0.00001546213,0.0005225113,0.0001942192,0.0001395688,0.0001591277],"domain_scores_gemma":[0.9979553,0.001315795,0.0004290149,0.00009386433,0.0001033965,0.0001026471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001606769,0.0001453806,0.01302018,0.0001444472,0.0001468513,0.000003798378,0.0001595855,2.924279e-7,0.9572989,0.000003489358,0.000004707621,0.02891173],"study_design_scores_gemma":[0.000510971,0.00005893523,0.02236633,0.0001895624,0.00003865896,0.0001683121,0.001593304,0.00004034039,0.9745356,0.0002505662,0.0001214939,0.0001258993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973944,0.001992282,0.00005273379,0.00009804786,0.00001269926,0.00002724159,0.000009737872,0.000005144237,0.0004076846],"genre_scores_gemma":[0.9980047,0.001338997,0.0004798284,0.00002231902,0.0001296119,0.000002203072,9.262976e-7,0.000006282401,0.00001507269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02878583,"threshold_uncertainty_score":0.4411574,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1972108472","doi":"10.1073/pnas.1203451109","title":"Electron transfer-based combination therapy of cisplatin with tetramethyl- <i>p</i> -phenylenediamine for ovarian, cervical, and lung cancers","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; University of Waterloo","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Cisplatin; Medicine; Cancer research; Cervical carcinoma; Oncology; Lung; Internal medicine; Cervical cancer; Urology; Chemistry; Chemotherapy; Cancer","retraction":null,"screen_n_in":null,"score":{"opus":0.05105792087978486,"gpt":0.3113916392533875,"spread":0.2603337183736026,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001117854,0.00007808294,0.000139386,0.00004787319,0.00008693283,0.000008330105,0.0002165651,0.00008857632,0.0000259869],"category_scores_gemma":[0.0003002179,0.00004343476,0.00004370861,0.0002573556,0.0004046119,0.0001882658,0.000009715436,0.00006992786,2.42585e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000349133,"about_ca_system_score_gemma":0.00003818815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006764911,"about_ca_topic_score_gemma":9.29721e-8,"domain_scores_codex":[0.9989163,0.000005053098,0.0002290273,0.000138957,0.0005809502,0.0001296865],"domain_scores_gemma":[0.9990948,0.0004241386,0.0002161565,0.00000616172,0.0002335233,0.00002524694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001314845,0.0000888056,0.0202834,0.0001168914,0.00001710764,1.498619e-10,0.00008437833,0.0000237185,0.9667512,0.0107189,0.00001836512,0.001765722],"study_design_scores_gemma":[0.0005428256,0.0001304972,0.04040415,0.00006421603,0.00001733154,5.050005e-7,0.00005950591,0.002631348,0.9526805,0.00334951,0.0000590947,0.00006051422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973469,0.000321792,0.00003189656,0.001216694,0.000005072005,0.0001650826,0.00001897276,0.000005815908,0.0008877625],"genre_scores_gemma":[0.997822,0.00005905707,0.001911556,0.0001188963,0.00004184305,0.00002957604,6.952583e-7,0.000003193886,0.0000132252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02012075,"threshold_uncertainty_score":0.1771218,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2074688003","doi":"10.1016/j.bmc.2009.04.021","title":"2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: A novel cluster of tumor-specific cytotoxins which reverse multidrug resistance","year":2009,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Aryl; Multiple drug resistance; Cytotoxicity; Efflux; Cell culture; Quinoxaline; Transfection; P-glycoprotein; Stereochemistry; In vitro; Biochemistry; Gene; Biology; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02760237183412785,"gpt":0.2570870981901068,"spread":0.2294847263559789,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008616273,0.0004831736,0.0007298704,0.00004217991,0.0001261739,0.00002978123,0.000731557,0.0004065622,0.004739758],"category_scores_gemma":[0.001360796,0.0003790203,0.0002024605,0.0004815303,0.0002269262,0.0001096143,0.0001021849,0.000535852,0.00004918156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002431951,"about_ca_system_score_gemma":0.0002030525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002072239,"about_ca_topic_score_gemma":0.00000695726,"domain_scores_codex":[0.9966307,0.00003373117,0.001034146,0.0008545422,0.0008882597,0.0005586075],"domain_scores_gemma":[0.9975828,0.0002443821,0.0005802223,0.0009052511,0.0004087348,0.0002786101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003661683,0.0003722205,0.0001620586,0.0002946146,0.00004087295,0.00001782623,0.0001337903,0.000001920629,0.9946134,0.00002423605,0.002861532,0.001111333],"study_design_scores_gemma":[0.001812786,0.00005777853,0.001690449,0.0006406243,0.00008535519,0.00005956583,0.0005941968,0.0001114843,0.9834559,0.0001129349,0.01090972,0.0004692232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806681,0.001580545,0.000250861,0.001934053,0.0001022826,0.0002195566,0.00009650059,0.0001647282,0.01498338],"genre_scores_gemma":[0.9944906,0.0001900642,0.001607578,0.0005169467,0.000802502,0.00001689364,0.0001038985,0.00003859889,0.002232984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01382244,"threshold_uncertainty_score":0.9998662,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2979999702","doi":"10.3390/molecules24203673","title":"Cinnamil- and Quinoxaline-Derivative Indicator Dyes for Detecting Volatile Amines in Fish Spoilage","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Guelph","funders":"Ministry of Agriculture, Food and Rural Affairs; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Quinoxaline; Chemistry; Trimethylamine; Food spoilage; Dimethylamine; Food packaging; Organic chemistry; Food science","retraction":null,"screen_n_in":null,"score":{"opus":0.01707494176718202,"gpt":0.2557122426810847,"spread":0.2386373009139026,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001373401,0.0001003595,0.0001521153,0.00003522198,0.00003429048,0.00002265209,0.0000719548,0.0001026043,0.0002076124],"category_scores_gemma":[0.0003210479,0.00007851079,0.00003412744,0.00005258415,0.00002874447,0.00003906324,0.0000382183,0.00006068045,0.000005850861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001873411,"about_ca_system_score_gemma":0.000008487448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001979588,"about_ca_topic_score_gemma":0.00005153488,"domain_scores_codex":[0.9993582,0.00001875543,0.0001714649,0.0002284739,0.00008050927,0.0001426178],"domain_scores_gemma":[0.9994951,0.0002704243,0.00008352567,0.00009947413,0.00002579148,0.00002570131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004878023,0.00002453307,0.04728852,0.00007102283,0.000008768113,8.691397e-7,0.0001412065,0.000005059214,0.9365019,0.0000460133,0.00003361547,0.01582966],"study_design_scores_gemma":[0.0006232596,0.00008106002,0.05221112,0.0000855898,0.0000110415,0.000001499604,0.0006106702,0.004661447,0.9397834,0.0007079514,0.001017091,0.0002059001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984941,0.0001164681,0.00009057219,0.0001601208,0.00002135782,0.0001263361,0.00002523957,0.00002993315,0.0009358981],"genre_scores_gemma":[0.9991405,0.00001437713,0.0004584136,0.0001406841,0.00004919057,0.0000430985,0.00002563529,0.00001048335,0.0001176149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01562376,"threshold_uncertainty_score":0.3201577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2951582670","doi":"10.1021/ol035859a","title":"Synthesis of β-Cyclopropylalanines by Photolysis of Diacyl Peroxides","year":2003,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Photodissociation; Photochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01021154406394323,"gpt":0.210360978725357,"spread":0.2001494346614138,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001990704,0.0001146633,0.0002659808,0.00002410525,0.00002514334,0.000005895392,0.0001397515,0.00008140576,0.006099218],"category_scores_gemma":[0.0008883171,0.00008422406,0.0001033354,0.0001197982,0.00008414387,0.0000327111,0.00001549706,0.00004946806,0.00001375221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002901749,"about_ca_system_score_gemma":0.00001532635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000279314,"about_ca_topic_score_gemma":0.000001397364,"domain_scores_codex":[0.9991494,0.00004978696,0.000287763,0.0001838662,0.0001924005,0.000136802],"domain_scores_gemma":[0.9992239,0.0003003504,0.000183637,0.0002228052,0.00003780902,0.00003143821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000799443,0.00006788168,0.0107078,0.00005132899,0.0000513447,4.911692e-7,0.00004048991,5.250893e-7,0.9864591,0.00001796831,0.001010066,0.001585023],"study_design_scores_gemma":[0.0001056841,0.000008571965,0.0008427207,0.00003055659,0.00006290286,0.000001781156,0.000110311,0.000006425255,0.9981846,0.00002246754,0.0005221012,0.000101833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978266,0.0001363643,0.00004876011,0.0004258853,0.00002181927,0.00003166621,0.00001838838,0.00002053512,0.001469999],"genre_scores_gemma":[0.9994231,0.00005563482,0.0002729596,0.0001473698,0.00001984521,0.000009867178,0.000005875437,0.00001311194,0.00005225238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01172556,"threshold_uncertainty_score":0.9948093,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1993658423","doi":"10.1016/j.bmcl.2007.04.052","title":"Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors","year":2007,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"Chemistry; Small molecule; Potency; Molecule; Pyrimidine; Stereochemistry; Combinatorial chemistry; Diamine; Drug discovery; Renin inhibitor; Renin–angiotensin system; IC50; High-throughput screening; In vitro; Biochemistry; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02216215381107691,"gpt":0.2380939689361161,"spread":0.2159318151250392,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007293314,0.0003140308,0.0003834968,0.00004244419,0.00006211358,0.00001993924,0.0003705721,0.0002933217,0.000924864],"category_scores_gemma":[0.0006400612,0.0002527748,0.0001877771,0.0002373572,0.0003085678,0.00005122775,0.00006148773,0.0003037737,0.00001137223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001699454,"about_ca_system_score_gemma":0.0001020165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005781648,"about_ca_topic_score_gemma":0.000003819408,"domain_scores_codex":[0.997808,0.00002384406,0.0006728626,0.0004874738,0.0005508645,0.0004569981],"domain_scores_gemma":[0.9986445,0.0003358415,0.0003544878,0.0004319226,0.0000794422,0.000153856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000137153,0.0001253294,0.002941457,0.0002093086,0.00003618518,0.00003627067,0.00003559418,0.000001622316,0.9943101,0.000002798846,0.0006139805,0.001550243],"study_design_scores_gemma":[0.0007214775,0.00002696647,0.001952661,0.0002022294,0.00008322854,0.00001289787,0.0001776833,0.00003587854,0.9961356,0.000008036678,0.0003546994,0.0002886725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943202,0.000311496,0.001019101,0.001707161,0.0001033959,0.00006756394,0.00001853426,0.00008397887,0.002368571],"genre_scores_gemma":[0.9980097,0.00001133766,0.0002876062,0.0007431851,0.0006301482,0.000006926907,0.0001150864,0.00003089813,0.0001651315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003689483,"threshold_uncertainty_score":0.9999924,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2088596854","doi":"10.1016/j.bmcl.2008.07.118","title":"Design, synthesis, and antibacterial activities of novel 3,6-bicyclolide oximes: Length optimization and zero carbon linker oximes","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Ryerson University","keywords":"Chemistry; Linker; Antibacterial activity; Combinatorial chemistry; Stereochemistry; Broad spectrum; Oxime; Zero (linguistics); Organic chemistry; Bacteria","retraction":null,"screen_n_in":null,"score":{"opus":0.03305665717636026,"gpt":0.2268447399122735,"spread":0.1937880827359133,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000269829,0.0002900799,0.0004370075,0.00003145051,0.0001065877,0.00001770907,0.0001467212,0.0003405546,0.0003365553],"category_scores_gemma":[0.0004679473,0.0002357065,0.00004901701,0.00008790936,0.0004827177,0.00007994252,0.00006635465,0.0002224889,3.530874e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005705989,"about_ca_system_score_gemma":0.0000646578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004250069,"about_ca_topic_score_gemma":2.14701e-7,"domain_scores_codex":[0.9985393,0.00003928812,0.0003959094,0.0004302069,0.000329269,0.0002659925],"domain_scores_gemma":[0.9988889,0.0004592102,0.0002635362,0.0002248318,0.0000445817,0.0001190131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001264394,0.0000747132,0.001764547,0.0002061312,0.0000719794,0.000008438045,0.0001667001,0.00002823296,0.9968456,5.320578e-7,0.00006350711,0.0006431991],"study_design_scores_gemma":[0.0007172765,0.00002341053,0.001269496,0.0001900574,0.0001263215,0.0001466447,0.0001735735,0.001517803,0.9955326,0.000003134346,0.00003752915,0.0002621376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963559,0.0004496632,0.001966743,0.0007759759,0.00005115686,0.00008604807,0.00001649379,0.00005844188,0.0002395585],"genre_scores_gemma":[0.9966478,0.000619488,0.00210628,0.0001590796,0.000369705,0.00001279118,0.00002215259,0.00002700751,0.00003574376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00148957,"threshold_uncertainty_score":0.9611832,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2770594517","doi":"10.1007/s00216-017-0756-1","title":"A fluorescent immunochromatographic strip test using a quantum dot-antibody probe for rapid and quantitative detection of 1-aminohydantoin in edible animal tissues","year":2017,"lang":"en","type":"article","venue":"Analytical and Bioanalytical Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":28,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"","keywords":"Detection limit; Chemistry; Fluorescence; Chromatography; Primary and secondary antibodies; Metabolite; Correlation coefficient; Linear range; Quantum dot; Coefficient of variation; Analytical Chemistry (journal); Antibody; Materials science; Nanotechnology; Biochemistry; Mathematics; Immunology","retraction":null,"screen_n_in":null,"score":{"opus":0.0552566081496628,"gpt":0.3404084784569829,"spread":0.28515187030732,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004700693,0.0002622697,0.0005687037,0.00006336447,0.0002171193,0.0001240364,0.0001991011,0.0003082014,0.0001091313],"category_scores_gemma":[0.001911778,0.0001982007,0.0001595724,0.0001366994,0.0008256759,0.0001175875,0.0001375339,0.0002034845,7.83994e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003605054,"about_ca_system_score_gemma":0.00004402493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001767767,"about_ca_topic_score_gemma":0.00001502079,"domain_scores_codex":[0.998245,0.00002021508,0.0005753204,0.0005414865,0.0002529715,0.0003650013],"domain_scores_gemma":[0.9986112,0.0005133016,0.000266136,0.0003085228,0.0001452499,0.000155554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002886022,0.0003034471,0.02687811,0.0005261321,0.00008574162,0.000006648378,0.00001632658,3.344889e-7,0.9692047,0.0003446245,0.000002005402,0.002343317],"study_design_scores_gemma":[0.001198039,0.000295148,0.02609425,0.0003681731,0.000314071,0.00002441612,0.0003149293,0.1762105,0.7934266,0.001324522,0.00006117864,0.0003681135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980021,0.0008061887,0.0003441887,0.0002569647,0.00001215151,0.000141682,0.00006338136,0.00001977322,0.0003536043],"genre_scores_gemma":[0.9989023,0.0002973692,0.0006292954,0.000008812943,0.00008245625,0.00001255581,0.00002329475,0.00001314037,0.00003080898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1762102,"threshold_uncertainty_score":0.8082392,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2052006422","doi":"10.1021/ma801123d","title":"“One-Pot” Synthesis of a Thermally Stable Blue Emitter: Poly[spiro(fluorene-9,9′-(2′-phenoxy-xanthene)]","year":2008,"lang":"en","type":"article","venue":"Macromolecules","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Citation; Fluorene; Xanthene; Computer science; Social media; Library science; World Wide Web; Information retrieval; Nanotechnology; Chemistry; Materials science; Organic chemistry; Polymer","retraction":null,"screen_n_in":null,"score":{"opus":0.03144748675556444,"gpt":0.2390988378677035,"spread":0.207651351112139,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002773694,0.000297961,0.0005039353,0.00006611524,0.0002294997,0.00003859449,0.0004802253,0.0002490511,0.003291952],"category_scores_gemma":[0.000411663,0.0002478602,0.0002465398,0.000161944,0.0003397387,0.0000738038,0.0001393514,0.0001500361,0.0001066937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005368289,"about_ca_system_score_gemma":0.00009738636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001825395,"about_ca_topic_score_gemma":0.000012708,"domain_scores_codex":[0.9979113,0.0001074827,0.0005533388,0.0004803622,0.0004871066,0.0004604223],"domain_scores_gemma":[0.9985623,0.0003538608,0.0002800776,0.0005597225,0.000125377,0.0001186123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000898592,0.0003326872,0.006222496,0.00009111322,0.0001225974,0.00003208307,0.0002710219,0.00001045468,0.9525318,0.0001156587,0.0001137467,0.04006651],"study_design_scores_gemma":[0.000291575,0.00005132642,0.008872096,0.0001262237,0.00008158384,0.00003309155,0.0001755098,0.0002306426,0.9882098,0.000292974,0.001287975,0.0003472051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777409,0.0009852365,0.0002250868,0.0002212845,0.00004114461,0.00009598338,0.000109307,0.0001210941,0.02045996],"genre_scores_gemma":[0.9968439,0.0002013522,0.001925046,0.0001654889,0.0001400635,0.00006597993,0.00002710544,0.00004219976,0.0005888559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03971931,"threshold_uncertainty_score":0.9999974,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2052087352","doi":"10.3390/md10081711","title":"Evaluation of Pseudopteroxazole and Pseudopterosin Derivatives against Mycobacterium tuberculosis and Other Pathogens","year":2012,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Nautilus Biosciences (Canada); University of Prince Edward Island","funders":"University of Prince Edward Island; Canada Research Chairs","keywords":"Mycobacterium tuberculosis; Antimicrobial; Cytotoxicity; Tuberculosis; Bacteria; Microbiology; In vitro; Biology; Antibiotics; Mycobacterium; Chemistry; Biochemistry; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03291976965589821,"gpt":0.2704292487154927,"spread":0.2375094790595945,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001078607,0.0001385612,0.0001823483,0.0000311871,0.00004733723,0.00002000406,0.00004855375,0.00009401606,0.00100278],"category_scores_gemma":[0.0001875166,0.0001065035,0.00003702554,0.00005159917,0.00008538333,0.0001064219,0.00009721486,0.00005635336,0.000004631196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003132639,"about_ca_system_score_gemma":0.00001102521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003471705,"about_ca_topic_score_gemma":0.000003411401,"domain_scores_codex":[0.9989978,0.0001032779,0.0002253,0.0001872623,0.0003076737,0.0001786877],"domain_scores_gemma":[0.9994579,0.00009608455,0.0001170187,0.0001543972,0.0001035128,0.00007107596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001957509,0.00009612396,0.332691,0.00005762512,0.00004481832,5.767136e-8,0.0006110556,0.000001262271,0.4144756,0.00005215959,0.00001575747,0.251935],"study_design_scores_gemma":[0.0008827181,0.00003365071,0.6901625,0.00006593095,0.0002590794,0.000005267357,0.0006642141,0.002075928,0.3035811,0.0003366532,0.001640272,0.0002926996],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682162,0.0003193858,0.000004951135,0.00008151915,0.00003447087,0.00008642556,0.00002235696,0.00002112596,0.03121353],"genre_scores_gemma":[0.9992186,0.0001199692,0.0003199765,0.0001112327,0.0001111211,0.00002993182,0.00002422277,0.00001169891,0.00005327521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3574715,"threshold_uncertainty_score":0.9999104,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}