{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":74,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":74,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"c3412ecd74e6","filters":{"topic":"Synthesis of heterocyclic compounds"}},"results":[{"id":"W2952378333","doi":"10.1055/s-2000-6416","title":"Expedient Synthesis of Symmetric Aryl Ketones and of Ambient-Temperature Molten Salts of Imidazole","year":2000,"lang":"en","type":"article","venue":"Synthesis","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":88,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Chemistry; Aryl; Ketone; Yield (engineering); Alkyl; Imidazole; Methyl Ketone; Medicinal chemistry; Ionic liquid; Organic chemistry; Combinatorial chemistry; Catalysis","authors":[{"name":"Philippe Lucas","is_ca":true},{"name":"Naïma El Mehdi","is_ca":true},{"name":"Hoang Anh Ho","is_ca":true},{"name":"Daniel Bélanger","is_ca":true},{"name":"Livain Breau","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00677589746778078,"gpt":0.2121279965174869,"spread":0.2053520990497061,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001904543,0.0005197354,0.0003880399,0.0002068881,0.000185798,0.0001774843,0.0004550072,0.0001589263,0.002579511],"category_scores_gemma":[0.0001488303,0.0001933081,0.000147709,0.0002051935,0.0001203702,0.0002602576,0.0002763581,0.0003840326,0.001620219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002146827,"about_ca_system_score_gemma":0.0004034929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003676714,"about_ca_topic_score_gemma":0.001238278,"domain_scores_codex":[0.9998841,0.00001139577,0.00001573962,0.00001809077,0.00004395717,0.00002666244],"domain_scores_gemma":[0.9999222,0.000009665634,0.00001860332,0.00001460421,0.0000153871,0.00001961085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009566902,0.00003173439,0.00005757161,0.0001480526,0.000006912715,0.0001342118,0.00003433184,0.0002387192,0.9924137,0.0005822684,0.0001681183,0.00608875],"study_design_scores_gemma":[0.00002195049,0.000185339,0.0003130715,0.00000634888,0.000008500562,0.0001650974,0.00001008141,0.0003861893,0.9933083,0.00007279196,0.005514449,0.000007900298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8950815,0.006607316,0.07695771,0.0002308385,0.0003507986,0.0004701036,0.002299502,0.001435249,0.01656701],"genre_scores_gemma":[0.9369283,0.005538842,0.04178243,0.00004748193,0.00005195,0.0002808398,0.001679104,0.0002556252,0.01343537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002579511,"threshold_uncertainty_score":0.008629322,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2973226651","doi":"10.1016/j.ejmech.2019.111687","title":"Recent advances in α,β-unsaturated carbonyl compounds as mitochondrial toxins","year":2019,"lang":"en","type":"review","venue":"European Journal of Medicinal Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":87,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chemistry; Mitochondrion; Cytotoxic T cell; Organelle; Conjugated system; Cytotoxicity; Toxicity; Biochemistry; In vitro; Organic chemistry","authors":[{"name":"Mohammad Hossain","is_ca":false},{"name":"Umashankar Das","is_ca":true},{"name":"Jonathan R. Dimmock","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03409391546560629,"gpt":0.3075493383903256,"spread":0.2734554229247193,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006777783,0.0008649271,0.00101034,0.001447013,0.0002669005,0.0009494383,0.000611843,0.0007339253,0.00382213],"category_scores_gemma":[0.0005269974,0.000323323,0.0003543252,0.002193888,0.0004941635,0.001215812,0.0006775125,0.00151722,0.001842723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005709847,"about_ca_system_score_gemma":0.0007057646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005056054,"about_ca_topic_score_gemma":0.001039067,"domain_scores_codex":[0.9998573,0.00002317067,0.0000148196,0.00003090585,0.00004430479,0.00002941956],"domain_scores_gemma":[0.9997835,0.00009332576,0.00003809365,0.000008888132,0.0000473676,0.00002892862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003599152,0.0002933066,0.0002312232,0.02204911,0.0001278321,0.0003750994,0.0001452174,0.001924275,0.02217928,0.01705309,0.02380457,0.9114571],"study_design_scores_gemma":[0.00005244641,0.0004252715,0.0006132218,0.0009847239,0.0001420445,0.0004771371,0.00005043808,0.0003804328,0.005724521,0.002937744,0.9881847,0.00002727951],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001417045,0.9926294,0.0008016478,0.0002984533,0.0004191798,0.00001308603,0.00004276988,0.00002220422,0.004356073],"genre_scores_gemma":[0.00538393,0.9919205,0.0005429874,0.0002444401,0.0003190208,0.00001121006,0.00004570182,0.000003774923,0.001528477],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00382213,"threshold_uncertainty_score":0.01278627,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049491848","doi":"10.1021/jm020354w","title":"Unique Structure−Activity Relationship for 4-Isoxazolyl-1,4-dihydropyridines","year":2002,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":66,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Chemistry; Stereochemistry; Structure–activity relationship; Biochemistry; In vitro","authors":[{"name":"Gerald W. Zamponi","is_ca":true},{"name":"Stephanie C. Stotz","is_ca":true},{"name":"Richard J. Staples","is_ca":true},{"name":"Tina M. Andro","is_ca":true},{"name":"Jared K. Nelson","is_ca":true},{"name":"Victoria Hulubei","is_ca":true},{"name":"Alex Blumenfeld","is_ca":true},{"name":"Nicholas R. Natale","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03255322276391724,"gpt":0.2614518641785267,"spread":0.2288986414146094,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001850667,0.000204231,0.0003472554,0.0001887453,0.00009822306,0.0002303455,0.0002093748,0.0001163724,0.0008870186],"category_scores_gemma":[0.0002631088,0.000105057,0.0001653457,0.0001611182,0.0001803539,0.0001557036,0.0001078605,0.0003235355,0.0002600131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001834005,"about_ca_system_score_gemma":0.0001159066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002088196,"about_ca_topic_score_gemma":0.0006775192,"domain_scores_codex":[0.9999276,0.00001559218,0.000009029452,0.00001770817,0.00001655176,0.00001340883],"domain_scores_gemma":[0.9998823,0.00002793816,0.00003596326,0.00001406674,0.00001686571,0.00002279333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003520938,0.00008836522,0.0008866278,0.0001395044,0.00001632945,0.0001572069,0.00005005874,0.0007049118,0.9865586,0.0003533284,0.00008968677,0.01060332],"study_design_scores_gemma":[0.0004175548,0.008806368,0.02188565,0.00002596535,0.0001661119,0.001960303,0.00006224708,0.00252691,0.9520749,0.0003307158,0.01170187,0.00004137069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874638,0.005703361,0.002789879,0.0001162166,0.00003749105,0.00006763316,0.0004561463,0.00005469229,0.003310827],"genre_scores_gemma":[0.9925503,0.002802865,0.002722671,0.00007762403,0.00001670602,0.00002666896,0.0007398674,0.000008021813,0.00105526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008870186,"threshold_uncertainty_score":0.002967358,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2087903625","doi":"10.1016/j.bmc.2007.04.017","title":"Substituted 6-amino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-ones: Synthesis, structure–activity relationships, and cytotoxic activity on selected human cancer cell lines","year":2007,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":64,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Welichem Biotech (Canada)","funders":"National Cancer Institute; Simon Fraser University","keywords":"Chemistry; Cytotoxic T cell; Stereochemistry; Chemical synthesis; Cell culture; Cancer cell lines; Structure–activity relationship; Cytotoxicity; Cancer; Amino acid; Cancer cell; In vitro; Biochemistry; Internal medicine; Genetics","authors":[{"name":"Bin Li","is_ca":true},{"name":"Michael P. A. Lyle","is_ca":true},{"name":"Genhui Chen","is_ca":true},{"name":"Jason Li","is_ca":true},{"name":"Kaiji Hu","is_ca":true},{"name":"Liren Tang","is_ca":true},{"name":"Moulay A. Alaoui‐Jamali","is_ca":true},{"name":"John Webster","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02289875559313844,"gpt":0.2656843360398503,"spread":0.2427855804467119,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001144089,0.0002260599,0.0002671077,0.0001938272,0.0001532361,0.0001445589,0.0003695053,0.0002070432,0.002078791],"category_scores_gemma":[0.0001358203,0.0001571236,0.00009351082,0.0002187193,0.0001119612,0.0001895012,0.0001166119,0.0002805232,0.0006244861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002149953,"about_ca_system_score_gemma":0.0001642069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003565839,"about_ca_topic_score_gemma":0.001765399,"domain_scores_codex":[0.9999177,0.00001775704,0.000006549691,0.00001293786,0.00001738896,0.00002753949],"domain_scores_gemma":[0.999936,0.00001246667,0.00001796325,0.000009247608,0.000008540283,0.00001568355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006898033,0.0001445315,0.0002539133,0.000213532,0.00001110285,0.0002044831,0.00006863998,0.000568872,0.9832432,0.0006164895,0.0003170453,0.01366836],"study_design_scores_gemma":[0.0001318916,0.002041892,0.003563363,0.0000132553,0.00003338197,0.0005039457,0.00002725417,0.001052837,0.9818923,0.00009354655,0.01062807,0.00001825798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748102,0.008334649,0.005626224,0.000140772,0.0001152353,0.00009729172,0.0007110084,0.0001895257,0.009975198],"genre_scores_gemma":[0.9830291,0.0043772,0.005120489,0.00007238556,0.00003820225,0.00006622175,0.0007800728,0.00002479057,0.006491528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002078791,"threshold_uncertainty_score":0.006954312,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3047946109","doi":"10.1016/j.bbrc.2020.06.123","title":"Pharmacological profile of natural and synthetic compounds with rigid adamantane-based scaffolds as potential agents for the treatment of neurodegenerative diseases","year":2020,"lang":"en","type":"review","venue":"Biochemical and Biophysical Research Communications","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":57,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lethbridge College","funders":"Russian Science Foundation","keywords":"Memantine; Amantadine; Adamantane; Dementia; Pharmacology; Medicine; Neuroscience; Chemistry; Disease; Psychology; Internal medicine","authors":[{"name":"Valery M. Dembitsky","is_ca":true},{"name":"Tatyana A. Gloriozova","is_ca":false},{"name":"Vladimir Poroikov","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.105611669749238,"gpt":0.4049724501247068,"spread":0.2993607803754689,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003421784,0.0007308843,0.0009573381,0.0009905536,0.0001446058,0.0006244093,0.0006233969,0.0004592862,0.002990767],"category_scores_gemma":[0.0002694684,0.0002109969,0.0003489489,0.0009747108,0.0002818749,0.0006002714,0.0003021095,0.00114097,0.001206485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002956255,"about_ca_system_score_gemma":0.0003784382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004797339,"about_ca_topic_score_gemma":0.001095836,"domain_scores_codex":[0.999938,0.000009817636,0.000007739151,0.00001263885,0.00002050451,0.00001133461],"domain_scores_gemma":[0.999916,0.00003216918,0.00001757219,0.000003359665,0.0000201191,0.00001083026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005334183,0.0003072877,0.0001856847,0.01942715,0.00017968,0.0004320884,0.0001041099,0.001318547,0.04782235,0.006636937,0.01341307,0.9096396],"study_design_scores_gemma":[0.0001459518,0.001229889,0.001644965,0.001808223,0.0003508123,0.001691922,0.0000707367,0.0004618832,0.01634281,0.002149449,0.9740492,0.00005417481],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002523516,0.9937699,0.000445512,0.0001364003,0.0001396569,0.00001866636,0.00008961229,0.00001713994,0.00285954],"genre_scores_gemma":[0.007751186,0.9894047,0.0005742194,0.0001558579,0.00008979211,0.00001644912,0.0001246561,0.000003236033,0.001879986],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002990767,"threshold_uncertainty_score":0.01000506,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2138992409","doi":"10.1021/jo0611061","title":"Highly Chemoselective Formation of Aldehyde Enamines under Very Mild Reaction Conditions","year":2006,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Aldehyde; Chemoselectivity; Ketone; Amine gas treating; Chemistry; Organic chemistry; Condensation; Enamine; Condensation reaction; Catalysis","authors":[{"name":"Guillaume Bélanger","is_ca":true},{"name":"M. Doré","is_ca":true},{"name":"Fréderic Ménard","is_ca":true},{"name":"Véronique Darsigny","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00875852093463904,"gpt":0.2212977798470205,"spread":0.2125392589123814,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005193484,0.0008030303,0.0003678486,0.0002824479,0.0001783958,0.0002131778,0.0004213624,0.0003647821,0.001147774],"category_scores_gemma":[0.0003549767,0.000212423,0.0002186174,0.0002056781,0.000255367,0.0004090286,0.0004105571,0.0004584682,0.000821784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001896239,"about_ca_system_score_gemma":0.0003064943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005938596,"about_ca_topic_score_gemma":0.002465595,"domain_scores_codex":[0.9996709,0.00006831825,0.00003285789,0.00008272408,0.00007354117,0.00007170152],"domain_scores_gemma":[0.999778,0.00005251223,0.00004819211,0.00002560746,0.00005166755,0.00004409575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004531422,0.00001150231,0.00006897986,0.00008492893,0.000009374932,0.00008349668,0.00002673529,0.00009076038,0.9972702,0.0001138073,0.00004266217,0.002152302],"study_design_scores_gemma":[0.000007260341,0.0001213894,0.0004552954,0.000003441422,0.00001015731,0.0001999391,0.000007774863,0.0001597481,0.9975448,0.00002678201,0.001455511,0.000007934841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9126989,0.006862945,0.06247862,0.0001780542,0.0001823898,0.0003220793,0.0009620559,0.0006405645,0.01567447],"genre_scores_gemma":[0.9727222,0.003375002,0.01824881,0.00007704439,0.00003015336,0.00006146019,0.0006181932,0.00005738064,0.004809818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001147774,"threshold_uncertainty_score":0.003839672,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2034322191","doi":"10.1021/ol0516519","title":"Addition of Tethered Nonaromatic Carbon Nucleophiles to Chemoselectively Activated Amides","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Iminium; Chemistry; Nucleophile; Enol; Silylation; Carbon fibers; Ring (chemistry); Nitrogen; Organic chemistry; Ion; Catalysis","authors":[{"name":"Guillaume Bélanger","is_ca":true},{"name":"Robin Larouche‐Gauthier","is_ca":true},{"name":"Fréderic Ménard","is_ca":true},{"name":"Miguel Nantel","is_ca":true},{"name":"Francis Barabé","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007719461371152025,"gpt":0.2055851930559364,"spread":0.1978657316847844,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001592148,0.0004765483,0.0001701243,0.0001907613,0.0001201105,0.0001872105,0.0003254699,0.0003119248,0.001876865],"category_scores_gemma":[0.0001987534,0.0001363778,0.0001737437,0.000116712,0.0002309436,0.0002947949,0.0002984623,0.0003823489,0.0005169284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001643524,"about_ca_system_score_gemma":0.0001487936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002354151,"about_ca_topic_score_gemma":0.0007351047,"domain_scores_codex":[0.999882,0.00002091505,0.00001131954,0.00003216901,0.00002454607,0.00002902591],"domain_scores_gemma":[0.9998845,0.00002807374,0.00003501786,0.00001884534,0.00001197526,0.00002158571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001254817,0.00003211499,0.0000697123,0.00008497068,0.000008029099,0.0002254381,0.00004013516,0.0002701568,0.9951907,0.0004488472,0.00005421992,0.003450091],"study_design_scores_gemma":[0.00001370008,0.0002060942,0.0002285621,0.000003212152,0.000006805491,0.00009457354,0.000006390735,0.000248501,0.9974661,0.00003952497,0.001682197,0.000004383002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800587,0.001523427,0.008011285,0.00007716712,0.00007662533,0.0001047836,0.0001807473,0.0001491114,0.00981814],"genre_scores_gemma":[0.9877656,0.0009007298,0.007180293,0.0000584,0.00002228105,0.00004858361,0.0001791646,0.00003243219,0.003812672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001876865,"threshold_uncertainty_score":0.006278753,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2018848798","doi":"10.1139/v06-133","title":"A simple and facile solventless procedure for the cyclization of 2′-amino- and 2′-hydroxy-chalcones using silica-supported sodium hydrogen sulphate as heterogenous catalyst","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Chemistry; Catalysis; Environmentally friendly; Silica gel; Sodium; Hydrogen Sulfate; Hydrogen; Organic chemistry","authors":[{"name":"K. Hemanth Kumar","is_ca":false},{"name":"Paramasivan T. Perumal","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01322926224260336,"gpt":0.2255794900621049,"spread":0.2123502278195016,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002366741,0.0007412403,0.0003822863,0.0004205187,0.0002777734,0.0001443463,0.0004284375,0.0004398893,0.003330416],"category_scores_gemma":[0.0001839446,0.0002281196,0.0003221707,0.0001944129,0.0003861694,0.0003025249,0.0002780259,0.000817181,0.001534002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000228722,"about_ca_system_score_gemma":0.000728838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008415446,"about_ca_topic_score_gemma":0.003020165,"domain_scores_codex":[0.9998459,0.00002206889,0.00001326749,0.00003231063,0.00005877397,0.00002773904],"domain_scores_gemma":[0.9998475,0.00004044845,0.00002625525,0.00002001339,0.00002670444,0.0000390492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000439908,0.00003457718,0.00006713901,0.0001517459,0.00001572106,0.0001868337,0.00003267514,0.0001090261,0.9912565,0.0001410639,0.0002024115,0.007758383],"study_design_scores_gemma":[0.0000346762,0.000542406,0.001429974,0.000007861346,0.00002326061,0.0008492424,0.00002074482,0.0002810713,0.9895085,0.0001103912,0.007157261,0.00003454403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6884977,0.01332933,0.2725283,0.0009556449,0.0007654577,0.001121031,0.002171158,0.00272566,0.01790581],"genre_scores_gemma":[0.9169813,0.006852418,0.06213583,0.0002929985,0.0001376847,0.0003331314,0.001649601,0.0001447905,0.01147213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003330416,"threshold_uncertainty_score":0.0111413,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2055284559","doi":"10.1016/j.tet.2004.05.025","title":"A convenient one-pot synthesis of substituted 2-pyrone derivatives","year":2004,"lang":"en","type":"article","venue":"Tetrahedron","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":31,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Shahid Bahonar University of Kerman; University of Toronto","keywords":"Chemistry; Ketene; Pyrone; Pyrimidine; Diketone; Organic chemistry; Combinatorial chemistry; Medicinal chemistry; Stereochemistry","authors":[{"name":"Hassan Sheibani","is_ca":false},{"name":"Mohammad Reza Islami","is_ca":false},{"name":"Hojatollah Khabazzadeh","is_ca":false},{"name":"Kazem Saidi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02070371272615714,"gpt":0.2376544677504155,"spread":0.2169507550242583,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002352253,0.0004385219,0.0003375067,0.0002936177,0.000303394,0.00020528,0.0004938311,0.0003197204,0.00421977],"category_scores_gemma":[0.0001389112,0.0002567857,0.0002229622,0.0002727183,0.0002092421,0.0003957268,0.000371412,0.0007977707,0.001474597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002712296,"about_ca_system_score_gemma":0.0005969182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003845755,"about_ca_topic_score_gemma":0.001258514,"domain_scores_codex":[0.9998405,0.00002287587,0.00001261103,0.00003260103,0.00003931003,0.00005201915],"domain_scores_gemma":[0.9999465,0.000008629958,0.000009482169,0.00001297637,0.000007584397,0.00001479705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001797583,0.0001701231,0.00009862518,0.0003911514,0.0000161775,0.0008473389,0.0001791217,0.001186785,0.9620908,0.007549069,0.001064272,0.02622685],"study_design_scores_gemma":[0.0001142508,0.001205281,0.001065644,0.00003697538,0.00002285734,0.001108425,0.00003846379,0.001215439,0.9548705,0.001340568,0.03893043,0.00005119311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7271111,0.009697328,0.1677014,0.0007634493,0.0007830692,0.0007766263,0.003216041,0.001227319,0.08872377],"genre_scores_gemma":[0.9284082,0.006471522,0.04420195,0.0002076754,0.00007536309,0.0002417807,0.0008228483,0.0001466098,0.01942408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00421977,"threshold_uncertainty_score":0.01411653,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2320499774","doi":"10.1097/mcd.0000000000000034","title":"Hajdu–Cheney syndrome","year":2014,"lang":"en","type":"article","venue":"Clinical Dysmorphology","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Classics","authors":[{"name":"Maria Descartes","is_ca":false},{"name":"Kitiwan Rojnueangnit","is_ca":false},{"name":"Laura E. Cole","is_ca":false},{"name":"Amelia Sutton","is_ca":false},{"name":"Sarah Morgan","is_ca":false},{"name":"Lysanne Patry","is_ca":true},{"name":"Mark Samuels","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.033951586517684,"gpt":0.3203613480149011,"spread":0.2864097614972171,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002604145,0.0008982645,0.0009286604,0.002177747,0.001925755,0.0007072786,0.0008632401,0.001594683,0.03547109],"category_scores_gemma":[0.001982135,0.0001988575,0.0004301218,0.001249623,0.0006903559,0.0007151554,0.0005774125,0.001408535,0.004259905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009971438,"about_ca_system_score_gemma":0.0010546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006960149,"about_ca_topic_score_gemma":0.006879401,"domain_scores_codex":[0.9994873,0.00005493917,0.00004492308,0.0001335513,0.0001824397,0.0000968362],"domain_scores_gemma":[0.9992179,0.0002986643,0.000105655,0.00006120235,0.00009790793,0.0002186265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.001074986,0.0003647286,0.01754313,0.0005867771,0.0002182485,0.6868458,0.0009884891,0.0004699756,0.02254631,0.0243482,0.108902,0.1361115],"study_design_scores_gemma":[0.0003178742,0.000265464,0.0309057,0.0006167736,0.0002188078,0.5605752,0.0004820044,0.0008151448,0.02766794,0.01645672,0.3614814,0.0001969594],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4366393,0.05007216,0.01170366,0.04275981,0.008916564,0.0009783604,0.02008856,0.00225612,0.4265854],"genre_scores_gemma":[0.8381305,0.01718046,0.01073643,0.005554478,0.001219775,0.0003078491,0.004651544,0.0003235668,0.1218955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03547109,"threshold_uncertainty_score":0.1186626,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2074919915","doi":"10.1021/jo062090h","title":"Amino Substituted Bisketenes:  Generation, Structure, and Reactivity","year":2007,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Centers for Disease Control and Prevention","keywords":"Chemistry; Reactivity (psychology); Amino acid; Biochemistry; Medicine","authors":[{"name":"Nanyan Fu","is_ca":true},{"name":"Annette D. Allen","is_ca":true},{"name":"Shinjiro Kobayashi","is_ca":true},{"name":"Thomas T. Tidwell","is_ca":true},{"name":"Siniša Vukovič","is_ca":true},{"name":"Selvananthan Arumugam","is_ca":true},{"name":"Vladimir V. Popik","is_ca":true},{"name":"Masaaki Mishima","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01390848118611223,"gpt":0.2302821930609566,"spread":0.2163737118748443,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007571506,0.0001857,0.0001025364,0.000132077,0.00008893164,0.0002637445,0.0002231628,0.0001995319,0.001051135],"category_scores_gemma":[0.0001236861,0.00009532242,0.0001160952,0.00009795489,0.0001162518,0.0002924928,0.00009437123,0.0002719414,0.0001915701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002705532,"about_ca_system_score_gemma":0.0000727833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004173371,"about_ca_topic_score_gemma":0.0006903549,"domain_scores_codex":[0.9999435,0.000006839076,0.000003100167,0.00001462329,0.00001631897,0.00001558952],"domain_scores_gemma":[0.9999405,0.00001225549,0.00002092075,0.000006898969,0.000008449949,0.00001090744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001743525,0.00003234739,0.0005204132,0.00006506123,0.000007684632,0.00006605052,0.00002988651,0.001325093,0.9942858,0.0006677862,0.00003946724,0.002785994],"study_design_scores_gemma":[0.00001105648,0.0003465164,0.001967557,0.000004768556,0.00001246689,0.0001839945,0.00002209829,0.002431139,0.9936237,0.0001312847,0.001256463,0.00000896182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966465,0.000897894,0.0007844345,0.0000167402,0.00000479953,0.00000574975,0.00011811,0.00001377578,0.001511954],"genre_scores_gemma":[0.9980072,0.0004138252,0.0006366702,0.000006341381,0.000001275494,0.000004118073,0.0001403079,0.000004631346,0.0007856187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001051135,"threshold_uncertainty_score":0.003516376,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2013936039","doi":"10.3390/molecules181214711","title":"Design and Synthesis of Arylthiophene-2-Carbaldehydes via Suzuki-Miyaura Reactions and Their Biological Evaluation","year":2013,"lang":"en","type":"article","venue":"Molecules","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"University of Karachi","keywords":"Chemistry; Pinacol; IC50; Combinatorial chemistry; Thiophene; Carbendazim; Scavenger; Benzonitrile; Nuclear chemistry; Organic chemistry; Catalysis; Biochemistry; Fungicide; In vitro; Antioxidant","authors":[{"name":"Shaukat Ali","is_ca":false},{"name":"Nasır Rasool","is_ca":false},{"name":"Aman Ullah","is_ca":true},{"name":"Faiz‐ul‐Hassan Nasim","is_ca":false},{"name":"Asma Yaqoob","is_ca":false},{"name":"Muhammad Zubaır","is_ca":false},{"name":"Umer Rashid","is_ca":false},{"name":"Muhammad Riaz","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03105888267465078,"gpt":0.2417947567776061,"spread":0.2107358741029553,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002891082,0.0007987071,0.0003143468,0.0004342702,0.0002184711,0.0002645492,0.0005385654,0.0004087731,0.001560472],"category_scores_gemma":[0.0002099287,0.000296166,0.0003767039,0.0004757169,0.0002486961,0.0003461968,0.0003349252,0.0004647142,0.0006346445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003253341,"about_ca_system_score_gemma":0.0004697935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000880595,"about_ca_topic_score_gemma":0.002203685,"domain_scores_codex":[0.9998217,0.00002799279,0.00001719957,0.00002930572,0.00003885492,0.00006498249],"domain_scores_gemma":[0.999897,0.00001124141,0.00003105646,0.0000108181,0.00002297033,0.00002684244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001368136,0.0001011102,0.0002242214,0.0005555014,0.00004824414,0.0006581975,0.00009598556,0.0013667,0.9810245,0.001572372,0.000201684,0.01401456],"study_design_scores_gemma":[0.00006407384,0.00135811,0.001595073,0.00002784222,0.000077752,0.0006090025,0.0000475405,0.001085672,0.9798781,0.0002398384,0.01497831,0.00003868515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8899385,0.02424918,0.0675711,0.0003738683,0.0002391787,0.0009614342,0.0009187855,0.0004389839,0.01530882],"genre_scores_gemma":[0.9550912,0.01064079,0.0291789,0.0001021507,0.00004233088,0.0003817166,0.0004664565,0.00003410679,0.004062334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001560472,"threshold_uncertainty_score":0.005220294,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2949561502","doi":"10.1055/s-2003-39398","title":"Synthesis of Aminopyrazolesfrom α- Oxoketene<i>O</i>,<i>N</i>-Acetals Using MontmorilloniteK-10/Ultrasound","year":2003,"lang":"en","type":"article","venue":"Synthesis","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Simon Fraser University; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Chemistry; Acetal; Ultrasound; Medicinal chemistry; Stereochemistry","authors":[{"name":"Mara E. F. Braibante","is_ca":false},{"name":"Hugo T. S. Braibante","is_ca":false},{"name":"Juliano K. da Roza","is_ca":false},{"name":"Danielle M. Henriques","is_ca":false},{"name":"Luciana de Carvalho Tavares","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02016830261728511,"gpt":0.2425633194009867,"spread":0.2223950167837016,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009818578,0.0003200721,0.0002557542,0.0001562241,0.0001776394,0.0001387898,0.0003010532,0.0002541031,0.002207902],"category_scores_gemma":[0.0001051804,0.0001965106,0.0002029786,0.0001503287,0.0001249811,0.0001807485,0.0001616521,0.0002900547,0.0008612908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002755924,"about_ca_system_score_gemma":0.0002733383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001190005,"about_ca_topic_score_gemma":0.002961536,"domain_scores_codex":[0.9999189,0.0000088599,0.000005535402,0.00001702272,0.00002198102,0.00002772546],"domain_scores_gemma":[0.9999505,0.000005576605,0.00001412004,0.000006389836,0.000009913774,0.00001358451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006777923,0.00001789795,0.00004644425,0.000096362,0.000004592472,0.0001159996,0.00003420247,0.0001124276,0.9966486,0.0002295911,0.00008333616,0.002542815],"study_design_scores_gemma":[0.00002665562,0.0003269307,0.0008193359,0.000005271366,0.000007868843,0.000178947,0.00001600148,0.0002880386,0.9933714,0.0000360891,0.004915971,0.000007598089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732611,0.003017015,0.01055598,0.0001181752,0.00008612521,0.000245028,0.0008739005,0.0003664528,0.01147625],"genre_scores_gemma":[0.9813783,0.002077526,0.008539353,0.00004903183,0.00001512786,0.00008358122,0.0005408999,0.00003725183,0.00727893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002207902,"threshold_uncertainty_score":0.007386208,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2020372143","doi":"10.1111/j.1540-8167.2007.00985.x","title":"Azimilide for the Treatment of Atrial Fibrillation, Atrial Flutter, and Paroxysmal Supraventricular Tachycardia: Results of a Randomized Trial and Insights on the Concordance of Symptoms and Recurrent Arrhythmias","year":2007,"lang":"en","type":"article","venue":"Journal of Cardiovascular Electrophysiology","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Hamilton Health Sciences","funders":"","keywords":"Medicine; Cardiology; Torsades de pointes; Atrial fibrillation; Atrial flutter; Internal medicine; Supraventricular tachycardia; Anesthesia; Placebo; Supraventricular arrhythmia; Tachycardia; QT interval","authors":[{"name":"Richard L. Page","is_ca":false},{"name":"Edward L.C. Pritchett","is_ca":false},{"name":"Stuart J. Connolly","is_ca":true},{"name":"William E. Wilkinson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01045834519652544,"gpt":0.24113101178711,"spread":0.2306726665905846,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00466203,0.0008925935,0.002283626,0.0003925441,0.0002510037,0.0008868694,0.0005469512,0.001237833,0.003134921],"category_scores_gemma":[0.004517729,0.0003958515,0.00293978,0.000490511,0.0007057485,0.0004828329,0.0002713791,0.001301979,0.0002679315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005661988,"about_ca_system_score_gemma":0.0008810536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009581472,"about_ca_topic_score_gemma":0.001451955,"domain_scores_codex":[0.9974457,0.001791943,0.0002131363,0.0002153841,0.0001832817,0.0001506493],"domain_scores_gemma":[0.9963631,0.001643552,0.001083371,0.0002673655,0.0002346638,0.0004079478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9684581,0.002106346,0.00689943,0.0008057593,0.005389859,0.00004897143,0.00004875112,0.0002317587,0.001108097,0.0001025253,0.0003626932,0.0144377],"study_design_scores_gemma":[0.9386995,0.03668178,0.01723119,0.00008524227,0.005979331,0.00007830854,0.0000288142,0.0003359811,0.0002679673,0.00009336977,0.0005031859,0.00001521539],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810669,0.01561329,0.0002658449,0.0004620494,0.0002695821,0.0007721612,0.0004750513,0.00002539843,0.001049609],"genre_scores_gemma":[0.9911262,0.005186628,0.0005413491,0.0003998072,0.0005171009,0.000843979,0.0007098785,0.000008401672,0.0006666419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00466203,"threshold_uncertainty_score":0.02465552,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2035344693","doi":"10.1139/v06-015","title":"Synthesis of some new 1-aryl-4-formyl-3-(4-hydroxy-6-methyl-2-oxo-2<i>H</i>-pyran-3-yl)pyrazoles using the Vilsmeier–Haack reaction — Isolation of the key intermediate 1-aryl-3-(4-hydroxy-6-methyl-2-oxo-2<i>H</i>-pyran-3-yl)pyrazoles","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Chemistry; Dehydroacetic acid; Pyran; Moiety; Reagent; Aryl; Medicinal chemistry; Organic chemistry","authors":[{"name":"Ajay Kumar","is_ca":false},{"name":"Om Prakash","is_ca":false},{"name":"Mayank Kinger","is_ca":false},{"name":"Shiv P. Singh","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01018670110184684,"gpt":0.2116761216142388,"spread":0.201489420512392,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766213,0.0004654147,0.0003234251,0.0002157527,0.0002413961,0.0001578341,0.0005293511,0.0004320042,0.001439517],"category_scores_gemma":[0.0001795785,0.0002325021,0.0003043744,0.0002468694,0.0002351959,0.0003708067,0.0002876859,0.0006158187,0.0006835104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000335582,"about_ca_system_score_gemma":0.0002976788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007621203,"about_ca_topic_score_gemma":0.001323594,"domain_scores_codex":[0.9998885,0.00001476361,0.00001122216,0.00002099669,0.0000199482,0.00004452632],"domain_scores_gemma":[0.9999195,0.000007703171,0.00002386963,0.000008252191,0.00001590084,0.00002477841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001032446,0.0000733093,0.000187281,0.0003171799,0.0000141762,0.0005329194,0.0001493496,0.0003716231,0.9922714,0.0008661101,0.0003113455,0.004801977],"study_design_scores_gemma":[0.00006808933,0.001241142,0.002169183,0.0000189994,0.00002933223,0.000632684,0.00007333328,0.0009415321,0.9820043,0.0001769674,0.01261374,0.0000306404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9573029,0.008756942,0.02101842,0.000342064,0.0002088409,0.0002702382,0.001132457,0.0004344095,0.01053373],"genre_scores_gemma":[0.980141,0.004306063,0.0101056,0.0001009158,0.00003697818,0.0001287191,0.0005085405,0.00002806335,0.004644205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001439517,"threshold_uncertainty_score":0.004815638,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2736674358","doi":"10.1055/s-0036-1588466","title":"Transition-Metal-Free One-Pot Tandem Synthesis of 4-Quinolone and 4H-Thiochromen-4-one Derivatives Through Sequential Nucleophilic Addition–Elimination–SNAr Reaction","year":2017,"lang":"en","type":"article","venue":"Synthesis","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Science North","funders":"Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China","keywords":"Chemistry; Nucleophilic aromatic substitution; Intramolecular force; Quinolone; Nucleophile; Enamine; Nucleophilic substitution; Medicinal chemistry; Combinatorial chemistry; Nucleophilic addition; Sodium hydride; Organic chemistry; Catalysis","authors":[{"name":"Jinsong Peng","is_ca":true},{"name":"Chunxia Chen","is_ca":true},{"name":"Deqiang Wang","is_ca":true},{"name":"Peng Sun","is_ca":true},{"name":"Peiyun Jia","is_ca":true},{"name":"Yixia Yue","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03515850820210877,"gpt":0.2609501070064791,"spread":0.2257915988043704,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001978053,0.0005612212,0.0004011934,0.0002398775,0.000208161,0.0002029494,0.0004859264,0.0003674487,0.002518419],"category_scores_gemma":[0.0001021176,0.0002275535,0.0002967519,0.000277537,0.0001996284,0.0003299381,0.0003173272,0.0004088247,0.001111584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002656061,"about_ca_system_score_gemma":0.0004050462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006013397,"about_ca_topic_score_gemma":0.002324146,"domain_scores_codex":[0.9998595,0.00001356457,0.00001098021,0.00003417582,0.00003266975,0.00004920337],"domain_scores_gemma":[0.9999502,0.000003428785,0.00001395217,0.000005391767,0.00001126682,0.00001570905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001170399,0.00008101037,0.0001084414,0.0003128638,0.00003672921,0.0004176799,0.0000799172,0.0004480782,0.9849186,0.001163664,0.0005125958,0.01180329],"study_design_scores_gemma":[0.00007138951,0.001101639,0.0007830893,0.00001549426,0.00006359009,0.0005962627,0.00003625985,0.00158649,0.9813074,0.0001996799,0.01420184,0.00003688904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9078418,0.009643302,0.05302732,0.0003565856,0.0003461926,0.0007636847,0.001395647,0.001247486,0.02537803],"genre_scores_gemma":[0.9676635,0.002983536,0.01919142,0.00008851437,0.00002351287,0.0001507994,0.0004060195,0.00003852213,0.009454114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002518419,"threshold_uncertainty_score":0.008424938,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2064669991","doi":"10.1139/v05-184","title":"Chemoselective thioacetalization with odorless 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid as a 1,3-propanedithiol equivalent","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Chemistry; Chemoselectivity; Ketene; Chloride; Acetyl chloride; Organic chemistry; Medicinal chemistry; Catalysis","authors":[{"name":"Haifeng Yu","is_ca":false},{"name":"Dewen Dong","is_ca":false},{"name":"Yan Ouyang","is_ca":false},{"name":"Qun Liu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008775805725186318,"gpt":0.210790347486089,"spread":0.2020145417609027,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001661409,0.0005282301,0.0001691628,0.0002539193,0.0001197974,0.0001368059,0.0002001838,0.0002098977,0.00106646],"category_scores_gemma":[0.0001230792,0.0001299862,0.000193243,0.000228423,0.0001635539,0.0002090873,0.0001811502,0.0003233394,0.0003365218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002147036,"about_ca_system_score_gemma":0.000321595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000675916,"about_ca_topic_score_gemma":0.002273945,"domain_scores_codex":[0.9998698,0.00001882196,0.000009232455,0.00002600933,0.00003738703,0.00003872638],"domain_scores_gemma":[0.9999057,0.00001294425,0.00002247258,0.000009773983,0.00001895457,0.00003014465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005559228,0.00001022952,0.00007629306,0.0000423148,0.000005292583,0.00005977938,0.00001089575,0.00004263054,0.9986411,0.000107075,0.00002064238,0.0009281542],"study_design_scores_gemma":[0.000006584348,0.000159387,0.0004698229,0.000001890269,0.000005835879,0.0001119306,0.00000788392,0.00009619064,0.9983034,0.000009559498,0.0008244187,0.000003051479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859976,0.001633057,0.005708279,0.00008116705,0.0000850789,0.0000757743,0.0003706046,0.00009446294,0.005953821],"genre_scores_gemma":[0.9915819,0.00115405,0.003517384,0.00004104956,0.00001131335,0.00002636591,0.0003577814,0.00001696545,0.003293157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00106646,"threshold_uncertainty_score":0.003567636,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1966072887","doi":"10.1021/ol0066375","title":"First Rational Synthesis of the Thiothiono Analogue of an Unsymmetrically Substituted Phthalic Anhydride","year":2000,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Phthalic anhydride; Chemistry; Derivative (finance); Benzaldehyde; Organic chemistry; Catalysis","authors":[{"name":"Christopher F. Morrison","is_ca":true},{"name":"D. Jean Burnell","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008379370382611653,"gpt":0.2028344458040649,"spread":0.1944550754214533,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002671556,0.0005666083,0.0003595779,0.0002110478,0.0002739433,0.0003254116,0.0004731892,0.0002707431,0.001408219],"category_scores_gemma":[0.0002974671,0.0002126589,0.0002504947,0.0002653525,0.0002532194,0.0002908555,0.000333617,0.0006724891,0.000696919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003658395,"about_ca_system_score_gemma":0.0007700216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007628756,"about_ca_topic_score_gemma":0.002220164,"domain_scores_codex":[0.999869,0.00001802499,0.00001035212,0.00002552747,0.00003733608,0.00003981192],"domain_scores_gemma":[0.999889,0.00001228998,0.00002302046,0.00001792716,0.00003496833,0.00002280762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009047701,0.0001178663,0.0002033614,0.0002350825,0.00001814636,0.0004764587,0.0001203955,0.001965815,0.97244,0.006498404,0.0005158911,0.01731815],"study_design_scores_gemma":[0.00003302152,0.0004664229,0.0003294591,0.000008736264,0.00001444737,0.0003485081,0.0000211347,0.00154985,0.9838832,0.000396343,0.01293562,0.00001317879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.826593,0.003944994,0.1254294,0.0006525497,0.0003606116,0.00158548,0.001008079,0.0006305601,0.03979525],"genre_scores_gemma":[0.9211489,0.004127844,0.06316216,0.00009301742,0.00004353929,0.0002603618,0.0006666704,0.000104296,0.0103933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001408219,"threshold_uncertainty_score":0.004710972,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2139235619","doi":"10.5267/j.ccl.2013.07.003","title":"Vilsmeier-Haack reagent: A facile synthesis of 2-(4-chloro-3,3-dimethyl-7-phenoxyindolin-2-ylidene)malonaldehyde and transformation into different heterocyclic compounds","year":2013,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"Urmia University","keywords":"Chemistry; Reagent; Transformation (genetics); Organic chemistry; Combinatorial chemistry; Medicinal chemistry","authors":[{"name":"Laya Roohi","is_ca":false},{"name":"Arash Afghan","is_ca":false},{"name":"Mehdi M. Baradarani","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01162892468903135,"gpt":0.2275845559937916,"spread":0.2159556313047603,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000374226,0.0006047166,0.0002427984,0.0004451908,0.0002730927,0.000181393,0.0005898612,0.0004992504,0.001461745],"category_scores_gemma":[0.0001866079,0.0002130206,0.000208821,0.0002560689,0.0002868543,0.0004228512,0.0002807918,0.0005306807,0.0008236231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003539145,"about_ca_system_score_gemma":0.0005232969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008357227,"about_ca_topic_score_gemma":0.001052468,"domain_scores_codex":[0.9997368,0.00004004253,0.0000194305,0.00005962201,0.00007487417,0.00006915331],"domain_scores_gemma":[0.9998946,0.00001324985,0.00003434752,0.00001363896,0.00002244066,0.00002173153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001122761,0.00003196784,0.000209125,0.0001871198,0.00001587796,0.0001609305,0.00004659636,0.000113214,0.9904364,0.001209973,0.0003490779,0.007127514],"study_design_scores_gemma":[0.00001076178,0.0002172694,0.0007308378,0.00000365812,0.00001095197,0.0002496849,0.000007183238,0.0002719592,0.991056,0.00006055979,0.007372892,0.000008284874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7597615,0.01565059,0.1982187,0.0006284168,0.0005710372,0.0006631116,0.00127225,0.002368151,0.02086613],"genre_scores_gemma":[0.9324093,0.003515613,0.04916492,0.0001525088,0.00005821961,0.0001760357,0.001088763,0.00007352997,0.01336112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001461745,"threshold_uncertainty_score":0.004890025,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2946380152","doi":"10.3762/bjoc.16.18","title":"The reaction of arylmethyl isocyanides and arylmethylamines with xanthate esters: a facile and unexpected synthesis of carbamothioates","year":2020,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"University of Mysore; Compute Canada","keywords":"Chemistry; Xanthate; Sodium hydride; Hydride; Condensation; Condensation reaction; Organic chemistry; Combinatorial chemistry; Photochemistry; Catalysis; Metal","authors":[{"name":"Narasimhamurthy Rajeev","is_ca":false},{"name":"Toreshettahally R. Swaroop","is_ca":true},{"name":"Ahmad I. Alrawashdeh","is_ca":true},{"name":"Shofiur Rahman","is_ca":true},{"name":"Abdullah N. Alodhayb","is_ca":false},{"name":"Seegehalli M. Anil","is_ca":false},{"name":"Kuppalli R. Kiran","is_ca":false},{"name":"Manasa Chandramouli","is_ca":false},{"name":"Paris E. Georghiou","is_ca":true},{"name":"Kanchugarakoppal S. Rangappa","is_ca":false},{"name":"Maralinganadoddi P. Sadashiva","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008639071550427167,"gpt":0.1952682795505893,"spread":0.1866292080001621,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000287662,0.0004707854,0.0002937017,0.0001968251,0.0001829715,0.000246824,0.0003654677,0.000394624,0.001041154],"category_scores_gemma":[0.0002761734,0.0002018119,0.0002584695,0.0001595977,0.0002542926,0.0004771259,0.0004370444,0.0005278521,0.0003761834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001941185,"about_ca_system_score_gemma":0.0001975576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001888884,"about_ca_topic_score_gemma":0.0004368502,"domain_scores_codex":[0.9998537,0.00002927395,0.00001526798,0.00003084344,0.00002935289,0.00004159512],"domain_scores_gemma":[0.9998797,0.00002302095,0.00003546234,0.00002305179,0.00001523081,0.00002339548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008414085,0.00002371537,0.0001995311,0.0001619772,0.00002196696,0.0004147056,0.00009232644,0.0001729939,0.9931573,0.0009834957,0.00007362085,0.004614119],"study_design_scores_gemma":[0.000009491628,0.0001545767,0.00032276,0.000004738314,0.00001154123,0.0002823506,0.00000975937,0.0001697938,0.9972823,0.00005876982,0.001687746,0.000006185097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722785,0.003903905,0.01513006,0.0001755696,0.0000918642,0.00007881097,0.0001802629,0.0001208336,0.008040237],"genre_scores_gemma":[0.9877986,0.002106737,0.007002734,0.00003363511,0.0000228447,0.00003939013,0.0001091347,0.00003484584,0.002852036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001041154,"threshold_uncertainty_score":0.003482997,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2950875613","doi":"10.1139/v04-029","title":"Preparation of 4-anilino-6-aryl-2<i>H</i>-pyran-2-ones from trilithiated acetoacetanilides and aromatic esters","year":2004,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Chemistry; Lithium diisopropylamide; Pyran; Aryl; Acylation; Organic chemistry; Medicinal chemistry; Stereochemistry; Catalysis","authors":[{"name":"Jennifer R. Downs","is_ca":false},{"name":"Sally P. Grant","is_ca":false},{"name":"Jessica D. Townsend","is_ca":false},{"name":"Deborah Schady","is_ca":false},{"name":"Stefan J. Pastine","is_ca":false},{"name":"Mildred C. Embree","is_ca":false},{"name":"Clyde R. Metz","is_ca":false},{"name":"William T. Pennington","is_ca":false},{"name":"Rosa D. Bailey Walsch","is_ca":false},{"name":"Charles F. Beam","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00986598629299728,"gpt":0.2280330927590695,"spread":0.2181671064660722,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001434534,0.0003565904,0.0001788534,0.0002988367,0.0001938602,0.0001695505,0.0002108006,0.0001579698,0.0020517],"category_scores_gemma":[0.0001129218,0.0001625016,0.0001873942,0.0001911316,0.0001615862,0.0002307825,0.0002240431,0.000407336,0.0007600044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002302436,"about_ca_system_score_gemma":0.0003788861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004169378,"about_ca_topic_score_gemma":0.001768843,"domain_scores_codex":[0.999913,0.00001198455,0.000006367502,0.00001538185,0.00002092438,0.00003232506],"domain_scores_gemma":[0.99993,0.000009030809,0.00001894077,0.000009385684,0.000009363683,0.00002313468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007206502,0.00002462185,0.00007742117,0.00006807328,0.000007480892,0.0001000336,0.0000467897,0.0002050679,0.9960608,0.0003498346,0.0000596665,0.002928043],"study_design_scores_gemma":[0.00003453128,0.0004297797,0.0009209207,0.00000462868,0.00001071853,0.0002036135,0.00001847505,0.0002108386,0.9946136,0.0000623906,0.00348318,0.000007391081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9720883,0.001636563,0.009072843,0.000102077,0.00005698002,0.0002525217,0.000658522,0.0001509096,0.01598112],"genre_scores_gemma":[0.980935,0.001298749,0.007892563,0.00005598192,0.00002147041,0.0001353047,0.0007844092,0.00004230152,0.008834207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0020517,"threshold_uncertainty_score":0.006863654,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4380997693","doi":"10.3390/molecules28124771","title":"Synthesis and Receptor Binding Studies of α5 GABAAR Selective Novel Imidazodiazepines Targeted for Psychiatric and Cognitive Disorders","year":2023,"lang":"en","type":"article","venue":"Molecules","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Mental Health Research Canada","funders":"Division of Chemistry; National Institute on Drug Abuse; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; University of Wisconsin-Milwaukee; University of North Carolina at Chapel Hill; National Institutes of Health; National Science Foundation","keywords":"Cognition; Psychiatry; Neuroscience; Psychology","authors":[{"name":"Dishary Sharmin","is_ca":false},{"name":"Md Yeunus Mian","is_ca":false},{"name":"Michael Marcotte","is_ca":true},{"name":"Thomas D. Prévot","is_ca":true},{"name":"Etienne Sibille","is_ca":true},{"name":"Jeffrey M. Witkin","is_ca":false},{"name":"James M. Cook","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02244567262809257,"gpt":0.282338692358558,"spread":0.2598930197304655,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001134775,0.0003633933,0.0002739352,0.000213346,0.0001425007,0.0000972635,0.0003316945,0.0001443723,0.002550665],"category_scores_gemma":[0.0001362704,0.000115808,0.0001481775,0.000222187,0.0001025073,0.0001333437,0.00009473107,0.0002757864,0.0004950235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003347005,"about_ca_system_score_gemma":0.0003020159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002043681,"about_ca_topic_score_gemma":0.00411754,"domain_scores_codex":[0.9999434,0.000008694648,0.000004805791,0.00001059446,0.00001599961,0.00001656538],"domain_scores_gemma":[0.9999623,0.000005802941,0.000007208775,0.00000510468,0.000009993762,0.000009546179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002068759,0.0001251943,0.00007126025,0.0001909904,0.00001390864,0.0001248711,0.00004728219,0.000817375,0.9891961,0.0004771481,0.0001915353,0.008537512],"study_design_scores_gemma":[0.000147615,0.002050931,0.001888308,0.00001899887,0.00004536773,0.0002728254,0.00003837179,0.001391032,0.9793125,0.00009786261,0.01471982,0.00001635621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9621211,0.005175689,0.01351215,0.000148463,0.00008286552,0.0006258363,0.002149718,0.0001414754,0.01604269],"genre_scores_gemma":[0.9734167,0.006757833,0.01017752,0.00008945854,0.00002419162,0.0001271239,0.00140761,0.00003143346,0.007968286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002550665,"threshold_uncertainty_score":0.008532822,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1987001986","doi":"10.1139/v02-010","title":"Studies on the rearrangement of <i>ortho</i>-nitrobenzylidenemalonates and their Analogues to 2-aminobenzoate derivatives","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"Florida International University","keywords":"Chemistry; Triethylamine; Trifluoromethyl; Nitro; Tetrahydrofuran; Medicinal chemistry; Regioselectivity; Diethylamine; Ring (chemistry); Michael reaction; Double bond; Carbon–carbon bond; Stereochemistry; Organic chemistry; Catalysis; Alkyl","authors":[{"name":"Elżbieta Lewandowska","is_ca":false},{"name":"Stefan Kinastowski","is_ca":false},{"name":"Stanislaw F. Wnuk","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04322403154334306,"gpt":0.2326501254520035,"spread":0.1894260939086605,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462638,0.0003599531,0.0001557735,0.0001648575,0.000130246,0.0001067747,0.0002434686,0.000192946,0.002421092],"category_scores_gemma":[0.0001752733,0.0001017916,0.0001646899,0.0001666386,0.0002083158,0.0001962642,0.00008367219,0.0002809723,0.0003848598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002535854,"about_ca_system_score_gemma":0.0002330336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001457136,"about_ca_topic_score_gemma":0.002331292,"domain_scores_codex":[0.9998962,0.00001861746,0.000004336277,0.00001657111,0.00002053289,0.00004388105],"domain_scores_gemma":[0.9999075,0.00002017276,0.00003029454,0.000006586969,0.00001741932,0.00001805394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001338435,0.0000326228,0.0001815631,0.00008042112,0.000009154714,0.0001168205,0.00007482246,0.0002012281,0.9969763,0.0003704198,0.00003732472,0.001785568],"study_design_scores_gemma":[0.000009565382,0.0005852289,0.001219595,0.000004559945,0.00001038091,0.0001733296,0.00003394014,0.0002838683,0.9960223,0.00004024255,0.001611752,0.000005275946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915352,0.001027235,0.001628447,0.0000492355,0.00001756634,0.00003494485,0.0001359903,0.00003038575,0.005540843],"genre_scores_gemma":[0.9948259,0.001020801,0.0009762574,0.00002257609,0.000005729949,0.00001623274,0.0001853936,0.00001335193,0.002933822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002421092,"threshold_uncertainty_score":0.008099318,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2151079400","doi":"10.1139/v10-015","title":"A novel approach towards the synthesis of tricyclic systems based on pyridine, pyran, thiopyran, azepine, oxepin, thiepin, and pyrimidine rings under different solvent conditions","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Thiopyran; Chemistry; Azepine; Pyran; Pyridine; Tricyclic; Pyrimidine; Solvent; Organic chemistry; Stereochemistry","authors":[{"name":"Anand Sachar","is_ca":false},{"name":"Poonam Gupta","is_ca":false},{"name":"Shallu Gupta","is_ca":false},{"name":"Richa Sharma","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01888170385598462,"gpt":0.219806866767612,"spread":0.2009251629116274,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009925745,0.0002804178,0.0002108221,0.0002121927,0.0001953714,0.0001512812,0.0002918157,0.0001574529,0.0008634318],"category_scores_gemma":[0.00006320635,0.00009313953,0.0001313261,0.0002046003,0.0001757186,0.0002282898,0.0002120388,0.0003123962,0.0001962431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002039424,"about_ca_system_score_gemma":0.0002981668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004225759,"about_ca_topic_score_gemma":0.001433075,"domain_scores_codex":[0.9999467,0.000006919966,0.000005673035,0.00001399083,0.00001604766,0.00001056064],"domain_scores_gemma":[0.9999691,0.000003387584,0.000008002211,0.000004706173,0.000005298105,0.000009560273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004199292,0.00003789373,0.00008936286,0.0001868786,0.00001255036,0.0002472773,0.00005933443,0.0002876373,0.9857329,0.00162452,0.00008773795,0.01159185],"study_design_scores_gemma":[0.00002858399,0.000719244,0.000701742,0.00001331497,0.00002596358,0.0007229178,0.00001884703,0.0008521791,0.9871054,0.0002724734,0.00952341,0.00001598365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9296945,0.009391577,0.0416018,0.0001803611,0.0001184188,0.0002712097,0.0004636217,0.0002080121,0.01807068],"genre_scores_gemma":[0.9518132,0.005585802,0.03803937,0.00006779866,0.0000234127,0.00008630314,0.0002851187,0.00001725724,0.004081641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008634318,"threshold_uncertainty_score":0.002888441,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1973610073","doi":"10.3390/molecules171213759","title":"Palladium-Catalyzed Multicomponent Synthesis of 2-Imidazolines from Imines and Acid Chlorides","year":2012,"lang":"en","type":"article","venue":"Molecules","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Decarboxylation; Chemistry; Aromatization; Palladium; Catalysis; Yield (engineering); Carbon monoxide; Benzoic acid; Organic chemistry; Nitrogen; Materials science","authors":[{"name":"Boran Xu","is_ca":true},{"name":"Kraig Worrall","is_ca":true},{"name":"Bruce A. Arndtsen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01518143773982425,"gpt":0.2297137112790175,"spread":0.2145322735391932,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002730763,0.0009148425,0.0006335482,0.0006277218,0.0002698918,0.0004282156,0.0009567669,0.0005169223,0.00181554],"category_scores_gemma":[0.0002084641,0.0004463098,0.0004012295,0.0005248014,0.0002108077,0.0007111782,0.000631078,0.0005849788,0.001448232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005073108,"about_ca_system_score_gemma":0.0003657509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004729996,"about_ca_topic_score_gemma":0.001766339,"domain_scores_codex":[0.9997345,0.00002185949,0.0000278186,0.00008389609,0.00007639029,0.00005561261],"domain_scores_gemma":[0.9999063,0.00001292553,0.00002101161,0.00001457746,0.00001615594,0.00002895169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000132392,0.00008870645,0.0001252211,0.0002777691,0.00002950081,0.0002249327,0.00005549287,0.001431602,0.9800051,0.0008901365,0.0002057089,0.01653335],"study_design_scores_gemma":[0.00003687879,0.0004058573,0.0003511469,0.000009921523,0.00002808915,0.0002784948,0.00001406667,0.001619677,0.9891374,0.0001457049,0.007951417,0.00002136015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8727784,0.01534915,0.08222323,0.0003234977,0.0002893423,0.0006681791,0.001215579,0.001187228,0.02596549],"genre_scores_gemma":[0.8917616,0.005609156,0.08920711,0.0001094031,0.00004412527,0.0002908618,0.0006255326,0.0001443411,0.01220786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00181554,"threshold_uncertainty_score":0.006073534,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144259831","doi":"10.1139/v02-175","title":"Structural and conformational studies of 5-(1<i>H</i>-pyrrol-2-ylmethylene)-substituted imidazolidine-2,4-diones and thiazolidine-2,4-diones","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Chemistry; Conformational isomerism; Imidazolidine; Thiazolidine; Hydantoin; Intramolecular force; Substituent; Stereochemistry; Nuclear magnetic resonance spectroscopy; Hydrogen bond; Molecule; Proton NMR; Cis–trans isomerism; Organic chemistry","authors":[{"name":"Alfonso de Dios","is_ca":false},{"name":"Marı́a Luz de la Puente","is_ca":false},{"name":"Alfonso Rivera‐Sagredo","is_ca":false},{"name":"Juan F. Espinosa","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03430708103366902,"gpt":0.2384183388258099,"spread":0.2041112577921408,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004684581,0.0001336617,0.00008101977,0.00007233431,0.00007475571,0.00008151692,0.0001155663,0.00007706361,0.0006759936],"category_scores_gemma":[0.0001032549,0.00006229453,0.00008870946,0.000107755,0.0001300884,0.00008410168,0.0000317329,0.000143155,0.00009035067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001823139,"about_ca_system_score_gemma":0.00009510171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001169311,"about_ca_topic_score_gemma":0.002109895,"domain_scores_codex":[0.9999806,0.000003414172,0.00000106006,0.000003800211,0.000005252876,0.000005929795],"domain_scores_gemma":[0.9999433,0.0000100158,0.00002366648,0.000004011522,0.00000689541,0.00001209273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001634532,0.00001329114,0.0004380012,0.00003608854,0.000005145994,0.00008021649,0.00003604145,0.0006961998,0.996873,0.0001298125,0.0000220769,0.001506834],"study_design_scores_gemma":[0.00004045632,0.001011651,0.01571879,0.000006470813,0.00003056434,0.0002706819,0.00005987558,0.002477008,0.9780478,0.00006620737,0.002257031,0.00001348912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981557,0.0006145389,0.0004543623,0.00001553039,0.000004357158,0.000004655497,0.0001408535,0.000005782698,0.0006042732],"genre_scores_gemma":[0.9981543,0.0004567214,0.0006045696,0.00001021564,0.000001853432,0.000004503486,0.0002351664,0.000002698735,0.000529819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001169311,"threshold_uncertainty_score":0.002325058,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011302663","doi":"10.1016/j.bbrc.2005.08.098","title":"Synthesis and evaluation of novel dipeptidyl benzoyloxymethyl ketones as caspase inhibitors","year":2005,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Chemistry; Combinatorial chemistry; Pharmacology; Biology","authors":[{"name":"Hinyu Nedev","is_ca":true},{"name":"Guy Klaiman","is_ca":true},{"name":"Andréa C. LeBlanc","is_ca":true},{"name":"H. Uri Saragovi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.129050952327548,"gpt":0.4036340704213957,"spread":0.2745831180938477,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002556174,0.0003866479,0.0003674406,0.0003057019,0.0001952829,0.0002547622,0.0003964572,0.0002221862,0.001738771],"category_scores_gemma":[0.0001317204,0.0001705305,0.0001889882,0.000248832,0.0001769094,0.0003336953,0.0001629319,0.0004599324,0.0004041464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004229734,"about_ca_system_score_gemma":0.0003187569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006830817,"about_ca_topic_score_gemma":0.001761334,"domain_scores_codex":[0.99989,0.00001563546,0.00001488518,0.00001552403,0.00002673057,0.00003729693],"domain_scores_gemma":[0.9999262,0.00000796685,0.00001894547,0.000006370502,0.00001535874,0.00002514642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008674723,0.0002358015,0.0002190184,0.0003139293,0.00003022363,0.0002968433,0.00005464605,0.001116435,0.9744613,0.0007063997,0.0004074179,0.0212905],"study_design_scores_gemma":[0.0005705608,0.004653363,0.001731312,0.00002932848,0.00008183454,0.0006798519,0.00003699387,0.001013184,0.9776154,0.0001275349,0.01343555,0.00002515291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9600036,0.02163641,0.008259308,0.0003161322,0.0001757873,0.0003844399,0.001000588,0.0001658838,0.00805795],"genre_scores_gemma":[0.9764736,0.01317303,0.005250611,0.0001058136,0.0000309763,0.0001124836,0.0007935936,0.00001714067,0.004042802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001738771,"threshold_uncertainty_score":0.005816698,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2529913715","doi":"10.1039/c6ra23493c","title":"A facile and highly chemoselective synthesis of 1-thia-3a,6-diaza-benzo[e]azulen-3-ones by 7-exo-dig/trig halocyclizations","year":2016,"lang":"en","type":"article","venue":"RSC Advances","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Discovery Centre","funders":"University of the Punjab","keywords":"Dig; Thiazole; Chemistry; Medicinal chemistry; Halogen; Aryl; Stereochemistry; Combinatorial chemistry; Organic chemistry; Computer science","authors":[{"name":"Bilash Kuila","is_ca":false},{"name":"Dinesh Mahajan","is_ca":true},{"name":"Prabhpreet Singh","is_ca":false},{"name":"Gaurav Bhargava","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007283402793924731,"gpt":0.2295679723889475,"spread":0.2222845695950228,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001561395,0.0004750775,0.0001898348,0.0002638761,0.0002336633,0.0001769345,0.0002756557,0.0002249586,0.001993305],"category_scores_gemma":[0.00009214086,0.0001612971,0.0002168655,0.0001625585,0.0001993946,0.0002018871,0.0003781554,0.0004144927,0.001120635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001954947,"about_ca_system_score_gemma":0.0003777358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003604304,"about_ca_topic_score_gemma":0.001302281,"domain_scores_codex":[0.9998958,0.00001580083,0.000008399798,0.00001899459,0.00002071914,0.00004034499],"domain_scores_gemma":[0.9999589,0.000004857528,0.00001146952,0.000006444927,0.000006167206,0.00001221851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009948209,0.000066068,0.0001957446,0.0002411797,0.00001774525,0.0004937687,0.000144614,0.0005217633,0.9794688,0.002131537,0.0004627618,0.01615656],"study_design_scores_gemma":[0.00004673852,0.0008208645,0.00173599,0.0000162565,0.00002039412,0.0008430278,0.00004313855,0.0007515465,0.9749492,0.0003997628,0.02033765,0.00003556377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9218248,0.007297903,0.03443827,0.0003994099,0.0001992224,0.0003610922,0.001503393,0.0004897242,0.03348621],"genre_scores_gemma":[0.976989,0.004071658,0.01185069,0.000124333,0.00003874905,0.0001221125,0.0004904213,0.00004995989,0.006263038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001993305,"threshold_uncertainty_score":0.00666827,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W16906298","doi":"10.1016/b978-0-08-097742-3.00830-2","title":"8.28 Reduction of SulfurCarbon Bonds and of Other Heteroatoms Bonded to Tetrahedral Carbon","year":2014,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Carleton University","funders":"","keywords":"Reagent; Heteroatom; Chemistry; Combinatorial chemistry; Tin; Sulfur; Triple bond; Nanotechnology; Organic chemistry; Materials science; Double bond; Ring (chemistry)","authors":[{"name":"Jeffrey M. Manthorpe","is_ca":true},{"name":"Han Il Kong","is_ca":true},{"name":"John W. Palko","is_ca":true},{"name":"Monica A. Gill","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01189732469163572,"gpt":0.2249920369897253,"spread":0.2130947122980896,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007465142,0.0005561772,0.000246977,0.0003981307,0.000259621,0.0003223796,0.0004754283,0.0004116246,0.03480788],"category_scores_gemma":[0.00005040924,0.0002065274,0.0004068707,0.0003531924,0.0003557795,0.0003861825,0.0003980838,0.000769682,0.0140854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004242933,"about_ca_system_score_gemma":0.000244298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000541883,"about_ca_topic_score_gemma":0.001079336,"domain_scores_codex":[0.9999212,0.000003595319,0.000002291998,0.00001292908,0.00004594053,0.0000141597],"domain_scores_gemma":[0.9999861,0.000003152805,0.000001492681,0.000002596857,0.000004186024,0.000002523717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001213501,0.0001423224,0.00009740968,0.001329236,0.0000268459,0.0005485373,0.0003568189,0.001285237,0.327341,0.1001301,0.08128337,0.4873377],"study_design_scores_gemma":[0.00001663085,0.0001994283,0.0005094172,0.0001228645,0.00001036173,0.0006179807,0.00006320535,0.000701637,0.1568777,0.0148042,0.8260579,0.00001872522],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.02829874,0.03056352,0.02933123,0.001218511,0.002237492,0.0001312164,0.0007141831,0.0005904989,0.9069147],"genre_scores_gemma":[0.06267007,0.01983174,0.01338181,0.0005292447,0.0002606174,0.0001042085,0.000863665,0.0002567825,0.9021019],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.03480788,"threshold_uncertainty_score":0.116444,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4285296313","doi":"10.5267/j.ccl.2022.4.004","title":"Synthesis, characterization and antimicrobial activity of some new isoxazole derivatives","year":2022,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"Saurashtra University; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Chemistry; Isoxazole; Antibacterial activity; Aspergillus niger; Acetic acid; Aryl; Proton NMR; Hydroxylamine Hydrochloride; Antimicrobial; Organic chemistry; Acetic anhydride; Carbon-13 NMR; Elemental analysis; Nuclear chemistry; Catalysis; Bacteria","authors":[{"name":"M. F. Dhaduk","is_ca":false},{"name":"H. S. Joshi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01482039794069868,"gpt":0.2309246520718568,"spread":0.2161042541311581,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001172563,0.0002933454,0.0002354306,0.0003783851,0.0001105105,0.0001955385,0.0002353087,0.0002126555,0.0007565097],"category_scores_gemma":[0.0001703808,0.00009945707,0.0002044909,0.0002525513,0.0001211991,0.0001891216,0.0000928716,0.0002946805,0.0002236369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001476762,"about_ca_system_score_gemma":0.0001341693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003121328,"about_ca_topic_score_gemma":0.000615481,"domain_scores_codex":[0.9999187,0.00001277413,0.00001137872,0.00001589578,0.00002936479,0.00001196382],"domain_scores_gemma":[0.9999111,0.000007348224,0.00002643662,0.00001005667,0.00002917954,0.00001582224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007480825,0.00008963517,0.0002437594,0.0001756453,0.000009332177,0.0001290454,0.0000186199,0.0002236653,0.9926737,0.0001053351,0.00006350929,0.00619291],"study_design_scores_gemma":[0.00003001655,0.001382085,0.00475081,0.00002279485,0.00003591267,0.0004523097,0.00003923496,0.0004130503,0.9856242,0.00005484071,0.007181271,0.00001356025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646793,0.02151836,0.007848507,0.0002258771,0.00006897395,0.0001574685,0.00104207,0.00007275505,0.004386777],"genre_scores_gemma":[0.9782532,0.00831385,0.009176362,0.000114367,0.00003171848,0.00008205882,0.0009433503,0.0000120799,0.003073141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007565097,"threshold_uncertainty_score":0.002530754,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2026645013","doi":"10.1016/j.tetlet.2012.07.100","title":"Regioselective synthesis of 2-iminooxazinones from dioxinones and carbodiimides","year":2012,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Regioselectivity; Stereochemistry; Organic chemistry; Combinatorial chemistry; Catalysis","authors":[{"name":"Jeffrey R. Johnston","is_ca":true},{"name":"F. G. West","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01194131773615764,"gpt":0.2143870032430027,"spread":0.2024456855068451,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002587827,0.0005642897,0.0003026628,0.000312629,0.0002260101,0.000173795,0.000537572,0.0002208657,0.002087684],"category_scores_gemma":[0.000157973,0.0001777765,0.0002255012,0.0003038311,0.0002279561,0.0002198886,0.0003484835,0.0005376924,0.0005526435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005049218,"about_ca_system_score_gemma":0.0004760193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007095034,"about_ca_topic_score_gemma":0.002095307,"domain_scores_codex":[0.9998369,0.00001966088,0.0000155435,0.00002241973,0.00003435353,0.00007111154],"domain_scores_gemma":[0.999929,0.0000119276,0.00001398612,0.00001185916,0.00001287316,0.00002044945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001717078,0.0001350178,0.0002433469,0.000308259,0.00001693033,0.0006395543,0.0002553951,0.001304681,0.9760982,0.003227252,0.0006689486,0.0169308],"study_design_scores_gemma":[0.00004081437,0.0002968257,0.001181044,0.00001207047,0.00001469533,0.0002565678,0.00002907432,0.0004501927,0.9886349,0.0002237507,0.008847157,0.00001292983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9193578,0.004836028,0.03576232,0.0004952419,0.0002922945,0.0004085898,0.001002506,0.0004942369,0.0373509],"genre_scores_gemma":[0.9749998,0.00327195,0.01021468,0.0001189067,0.00003043734,0.0001396343,0.0006033691,0.00006733675,0.0105538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002087684,"threshold_uncertainty_score":0.006983995,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4387417581","doi":"10.5267/j.ccl.2023.7.004","title":"Convenient and versatile method of 8-amino-6-(2-R-thiazol-4-yl)-1,7-naphthyridines synthesis","year":2023,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"Enamine","keywords":"Chemistry; Thiazole; Trifluoromethanesulfonate; Halogenation; Pyrone; Aniline; Stereochemistry; Ammonia; Medicinal chemistry; Combinatorial chemistry; Organic chemistry; Catalysis","authors":[{"name":"Artem S. Konovalenko","is_ca":false},{"name":"Oleh Shablykin","is_ca":false},{"name":"Olga V. Shablykina","is_ca":false},{"name":"Andrii Kozytskyi","is_ca":false},{"name":"В. С. Броварец","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02341858931175894,"gpt":0.2805805282756306,"spread":0.2571619389638717,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001336246,0.0004260214,0.0002602656,0.0002490933,0.0002083204,0.0001256145,0.0003524336,0.0002842213,0.001243723],"category_scores_gemma":[0.00009027161,0.0001847802,0.0001607912,0.0001298028,0.0001485337,0.0002037572,0.0002519892,0.0004755101,0.0008972676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000165167,"about_ca_system_score_gemma":0.0002957532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002793936,"about_ca_topic_score_gemma":0.0008092695,"domain_scores_codex":[0.9998887,0.00001956174,0.000009186248,0.00002986857,0.00002982977,0.00002287795],"domain_scores_gemma":[0.9999558,0.00000529152,0.00001178796,0.000008278438,0.000009160304,0.000009725673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003359365,0.00002240949,0.00005594435,0.0002112824,0.000007084891,0.0001873577,0.00006492747,0.000208527,0.9899268,0.0007375463,0.0001746044,0.008369911],"study_design_scores_gemma":[0.00003213269,0.0003470877,0.0006166133,0.00001439937,0.00001449645,0.0008170482,0.00002132863,0.0007388046,0.9779599,0.0001692321,0.01924836,0.00002052145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7727378,0.0229564,0.1647936,0.0004422756,0.0003394294,0.0009162254,0.001290301,0.001361582,0.03516243],"genre_scores_gemma":[0.9129108,0.00668428,0.06923728,0.00008862514,0.0000555389,0.0003934122,0.0005820102,0.00006994391,0.009978029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001243723,"threshold_uncertainty_score":0.004160643,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3148355523","doi":"10.6023/cjoc201207046","title":"Progress in the Synthesis and Applications of 2-Imidazolines","year":2013,"lang":"en","type":"article","venue":"Chinese Journal of Organic Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Science North","funders":"","keywords":"Chemistry; Combinatorial chemistry","authors":[{"name":"Baoyue Zhou","is_ca":true},{"name":"Jin Zhang","is_ca":true},{"name":"Xiangnan Li","is_ca":true},{"name":"Mengyao She","is_ca":true},{"name":"Jing Zhang","is_ca":true},{"name":"Jianli Li","is_ca":true},{"name":"Zhen Shi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005512474882492629,"gpt":0.2320127970766105,"spread":0.2265003221941178,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005073004,0.0006174139,0.0004945846,0.0007731303,0.0002699819,0.0003756246,0.000432591,0.0004376937,0.001540621],"category_scores_gemma":[0.000271971,0.0003213587,0.0003399249,0.0006122666,0.0002765384,0.0008720979,0.0003766311,0.0006278337,0.0007569351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003528043,"about_ca_system_score_gemma":0.0005784737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004661686,"about_ca_topic_score_gemma":0.0008053174,"domain_scores_codex":[0.999799,0.00002640612,0.00002553227,0.00006090166,0.00006259845,0.00002567064],"domain_scores_gemma":[0.999912,0.00002025385,0.00002517226,0.000008040821,0.00002423154,0.00001038425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000252157,0.0002281516,0.0006869873,0.009753756,0.00007255897,0.0006879006,0.0004691275,0.002748371,0.5627291,0.01258372,0.004226314,0.4055619],"study_design_scores_gemma":[0.0000743523,0.001347671,0.002873674,0.0005358887,0.000161793,0.002590997,0.0001407425,0.003037063,0.436621,0.002989765,0.5495278,0.00009938284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05798704,0.8957986,0.02050311,0.0007757056,0.0005164086,0.00007701201,0.0001900113,0.0001594153,0.02399274],"genre_scores_gemma":[0.1943458,0.7731748,0.02470139,0.000385506,0.0005604319,0.00009172924,0.0002693738,0.00004701475,0.006424038],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001540621,"threshold_uncertainty_score":0.005153954,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4307987317","doi":"10.26434/chemrxiv-2022-9r8hl","title":"A Purification-Free Method for the Synthesis of Thiazolium Salts Using P2S5-Py2 Complex or P4S10","year":2022,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Reagent; Chemistry; Tetrafluoroborate; Salt (chemistry); Sodium tetraphenylborate; Salt metathesis reaction; Metathesis; Combinatorial chemistry; Sodium; Organic chemistry; Ion; Ionic liquid; Catalysis","authors":[{"name":"Tianqi Ji","is_ca":true},{"name":"Venkata Krishna Rao Garapati","is_ca":true},{"name":"Michel Gravel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1083449834794457,"gpt":0.3505895997859936,"spread":0.242244616306548,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002717172,0.000659406,0.0004047046,0.0004715419,0.0003940407,0.0003636147,0.0006775351,0.0005512105,0.004689263],"category_scores_gemma":[0.0002810961,0.0003702508,0.0003357206,0.0003907249,0.0002710815,0.0003722769,0.0004527811,0.001282755,0.004654222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002760055,"about_ca_system_score_gemma":0.0006069147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005949663,"about_ca_topic_score_gemma":0.0009428554,"domain_scores_codex":[0.9997333,0.00002507529,0.00002164878,0.00006302724,0.0001148497,0.00004198159],"domain_scores_gemma":[0.9998711,0.00002428294,0.00002069606,0.00004068152,0.00002572283,0.00001737787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005651716,0.00005651495,0.00007664345,0.0002560614,0.00002810913,0.000221841,0.000060608,0.0002124269,0.9796017,0.001299367,0.00110487,0.01702526],"study_design_scores_gemma":[0.00002082682,0.0001271069,0.0003191786,0.000007849422,0.00001588802,0.000489589,0.00001021491,0.0006072298,0.9855478,0.0002263089,0.01260967,0.00001852739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.433766,0.005958249,0.5136333,0.0007960843,0.0004948008,0.001116903,0.003468231,0.005019526,0.03574698],"genre_scores_gemma":[0.7583663,0.005747862,0.2018554,0.0002377253,0.00008039123,0.0007811402,0.004029804,0.000642956,0.02825842],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004689263,"threshold_uncertainty_score":0.01568717,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W7117458190","doi":"10.3389/fchem.2025.1740409","title":"Regioselective synthesis of novel spiro-isoxazolines congeners as antimicrobial agents: in vitro and in-silico assessments","year":2025,"lang":"en","type":"article","venue":"Frontiers in Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"King Saud University","keywords":"Antimicrobial; Docking (animal); Candida albicans; Steric effects; In vitro; Drug; Bioavailability; Antifungal; Bacteria","authors":[{"name":"Rachid Bouzammit","is_ca":false},{"name":"Soumia Ait Assou","is_ca":false},{"name":"M. Er-rajy","is_ca":false},{"name":"Noura Aflak","is_ca":false},{"name":"Lahoucine Bahsis","is_ca":false},{"name":"Mohammed Chalkha","is_ca":false},{"name":"Mohammed El Hassouni","is_ca":false},{"name":"Mohammed Lachkar","is_ca":false},{"name":"Taïbi Ben Hadda","is_ca":false},{"name":"Daryn Benson","is_ca":false},{"name":"Abdullah A. Alyousef","is_ca":false},{"name":"Mourad A. M. Aboul-Soud","is_ca":false},{"name":"John P. Giesy","is_ca":true},{"name":"Ghali Al Houari","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01343813294628322,"gpt":0.2833862219598977,"spread":0.2699480890136144,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003892053,0.0004904267,0.0003898959,0.0002772773,0.0001268501,0.0002789265,0.0003950497,0.0002919103,0.001359378],"category_scores_gemma":[0.0002893131,0.0001969548,0.0004011272,0.0002213714,0.000154494,0.0002799306,0.0002205778,0.0004031987,0.0005533933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002266045,"about_ca_system_score_gemma":0.0002354544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002289996,"about_ca_topic_score_gemma":0.0006304096,"domain_scores_codex":[0.9998192,0.00003887495,0.00001917235,0.00003717853,0.00005114569,0.00003439957],"domain_scores_gemma":[0.9999102,0.00001261588,0.00003282651,0.00001119279,0.00001981827,0.00001338217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002082886,0.0001855057,0.0004863652,0.0006414229,0.00003496058,0.0003617554,0.0000590918,0.002303235,0.9841729,0.0006006791,0.0002500746,0.01069563],"study_design_scores_gemma":[0.00006710341,0.003160227,0.001587016,0.00005194031,0.0000634908,0.0005420202,0.00004893134,0.002774414,0.9822234,0.000182491,0.009268293,0.00003073683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9642057,0.01167815,0.01266742,0.0002135431,0.00008443026,0.0003862962,0.001255383,0.0002085677,0.00930039],"genre_scores_gemma":[0.9836364,0.004634995,0.009079996,0.00005701684,0.00001717256,0.0001228776,0.0004991583,0.00002227337,0.001930022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001359378,"threshold_uncertainty_score":0.004547536,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4243778046","doi":"10.3762/bxiv.2019.26.v1","title":"<i>Reaction of Arylmethyl Isocyanides/Arylmethyl-amines with Xanthate Esters: A Facile and Unexpected Synthesis of Carbamothioates</i>","year":2019,"lang":"en","type":"preprint","venue":"","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"Deanship of Scientific Research, King Saud University; University of Mysore; King Saud University; Compute Canada","keywords":"Xanthate; Chemistry; Sodium hydride; Condensation; Hydride; Sodium; Condensation reaction; Medicinal chemistry; Organic chemistry; Inorganic chemistry; Catalysis; Metal","authors":[{"name":"Narasimhamurthy Rajeev","is_ca":false},{"name":"Toreshettahally R. Swaroop","is_ca":true},{"name":"Seegehalli M. Anil","is_ca":false},{"name":"Kupalli R Kiran","is_ca":false},{"name":"Chandru Chandru","is_ca":false},{"name":"Paris E. Georghiou","is_ca":true},{"name":"Ahmad I. Alrawashdeh","is_ca":true},{"name":"Shofiur Rahman","is_ca":true},{"name":"Abdullah N. Alodhayb","is_ca":false},{"name":"Kanchugarakoppal S. Rangappa","is_ca":false},{"name":"Maralinganadoddi P. Sadashiva","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01265597688975364,"gpt":0.2246415693904715,"spread":0.2119855925007179,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001630491,0.0004026011,0.0002257271,0.0001309653,0.0001424768,0.0001942639,0.0002551069,0.0002770706,0.001647721],"category_scores_gemma":[0.0002020967,0.0001147467,0.0001863565,0.0001144707,0.000163017,0.0002858026,0.0002854896,0.0003121155,0.000600638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001240984,"about_ca_system_score_gemma":0.0001096148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001838154,"about_ca_topic_score_gemma":0.0003194018,"domain_scores_codex":[0.9999119,0.00001488497,0.000007832451,0.000023254,0.00001703075,0.0000250758],"domain_scores_gemma":[0.9999286,0.00001256278,0.00002400423,0.00001322831,0.00001037565,0.00001127451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008882036,0.00001596785,0.0001478959,0.0001716578,0.00001544166,0.0002739523,0.00004905964,0.0001128309,0.9946452,0.0005730008,0.000111584,0.003794625],"study_design_scores_gemma":[0.000004266471,0.00009748709,0.0002619378,0.000003623871,0.000005664669,0.000168103,0.000005218742,0.0001300932,0.997704,0.00003319328,0.001583502,0.000002882123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746848,0.002942298,0.009078313,0.0001461011,0.00009533471,0.00005503251,0.0002850151,0.0001241359,0.01258907],"genre_scores_gemma":[0.9896311,0.001657367,0.005008211,0.00003786272,0.00002560173,0.00003259456,0.0001971353,0.00004582092,0.003364373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001647721,"threshold_uncertainty_score":0.005512118,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3148156944","doi":"10.5267/j.ccl.2021.1.003","title":"Synthesis of novel ketene dithioacetals via one pot reaction: Molecular modelling in-silico Admet studies and antimicrobial activity","year":2021,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Ketene; Chemistry; Malononitrile; Combinatorial chemistry; In silico; Lipinski's rule of five; Docking (animal); Antimicrobial; Stereochemistry; Methylene; Organic chemistry; Biochemistry","authors":[{"name":"Mohammad Arif Pasha","is_ca":false},{"name":"Sumanta Mondal","is_ca":false},{"name":"Naresh Panigrahi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04604843595781274,"gpt":0.2750082322033948,"spread":0.2289597962455821,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001888173,0.0003680608,0.0003839098,0.0002978923,0.0001248054,0.0003418142,0.0003556604,0.0003414674,0.001553884],"category_scores_gemma":[0.0002485811,0.0002363104,0.0003774051,0.0003053792,0.0001056099,0.0003258087,0.0002419118,0.0005217614,0.0004484481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000258859,"about_ca_system_score_gemma":0.0001989929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004339677,"about_ca_topic_score_gemma":0.001064913,"domain_scores_codex":[0.999912,0.00001606465,0.000008852845,0.00002222714,0.00002642523,0.0000144198],"domain_scores_gemma":[0.9999393,0.00001189564,0.00001707356,0.000006169409,0.00001287171,0.00001266025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003575681,0.0002831795,0.0007624584,0.001084992,0.0001117796,0.0005526784,0.00009975434,0.01292995,0.9596532,0.001836518,0.0005074093,0.02182045],"study_design_scores_gemma":[0.00009257789,0.00202798,0.0008906701,0.0000257868,0.0001030002,0.0004858777,0.00004455568,0.01307788,0.971965,0.0002391593,0.01100417,0.00004328867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9421136,0.009519402,0.03963106,0.0002776829,0.00008739589,0.0003313394,0.001503955,0.0004610553,0.006074609],"genre_scores_gemma":[0.9589106,0.00484259,0.03156258,0.00005625479,0.000009174903,0.0001555931,0.0007142439,0.00003386326,0.003715021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001553884,"threshold_uncertainty_score":0.0051983,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4403001351","doi":"10.1016/j.tet.2024.134286","title":"Synthesis of exocyclic enaminone-based thiohydantoins as potent antifungal agents","year":2024,"lang":"en","type":"article","venue":"Tetrahedron","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Secretaría de Investigación y Posgrado, Instituto Politécnico Nacional; Instituto Politécnico Nacional; Consejo Nacional de Ciencia y Tecnología; Swine Innovation Porc","keywords":"Chemistry; Antifungal; Combinatorial chemistry; Stereochemistry; Organic chemistry; Microbiology","authors":[{"name":"Ulises F. Reyes-González","is_ca":false},{"name":"Edson Barrera","is_ca":false},{"name":"D. Martínez-López","is_ca":false},{"name":"R. Israel Hernández‐Benitez","is_ca":false},{"name":"Julio López","is_ca":false},{"name":"Omar Gómez‐García","is_ca":false},{"name":"Dulce Andrade-Pavón","is_ca":false},{"name":"Lourdes Villa‐Tanaca","is_ca":false},{"name":"Paola Castillo-Juárez","is_ca":false},{"name":"Francisco Delgado","is_ca":false},{"name":"Joaquı́n Tamariz","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01711492237888656,"gpt":0.2678943184933396,"spread":0.250779396114453,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442586,0.000402244,0.000248883,0.0002517675,0.0001911903,0.000217184,0.0003219315,0.0002418744,0.003216597],"category_scores_gemma":[0.00009672806,0.0001334721,0.0001663415,0.0002364066,0.0001535286,0.000210139,0.0002212412,0.0003852456,0.0008153419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002412123,"about_ca_system_score_gemma":0.0003406594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004136497,"about_ca_topic_score_gemma":0.001545269,"domain_scores_codex":[0.9999272,0.00001398131,0.000006109502,0.00001038459,0.00001783051,0.00002447012],"domain_scores_gemma":[0.9999661,0.000004333855,0.00000738433,0.000003945847,0.000005735608,0.0000124199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00028836,0.0001858544,0.0001772126,0.0004190602,0.0000281077,0.0009024669,0.0001395922,0.002292454,0.9577189,0.00729976,0.0009598488,0.02958841],"study_design_scores_gemma":[0.0001653794,0.002354234,0.001582358,0.00007201015,0.000060108,0.0006525206,0.00009001826,0.002482151,0.9471589,0.001046359,0.04429943,0.00003661533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8699636,0.01469747,0.04265152,0.0005461653,0.0005534348,0.0004293454,0.001373666,0.000411484,0.06937333],"genre_scores_gemma":[0.965866,0.008877067,0.01249483,0.0001263635,0.00005956977,0.00009343564,0.0004074583,0.00003371435,0.01204159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003216597,"threshold_uncertainty_score":0.01076061,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2038256932","doi":"10.1002/chin.200731245","title":"Halogen‐Substituted Ketenes","year":2007,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Halogen; Combinatorial chemistry; Organic chemistry","authors":[{"name":"T. T. Tidwell","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01545520919468011,"gpt":0.2427725807524456,"spread":0.2273173715577655,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002108063,0.0006880348,0.0003310062,0.0006195392,0.0004716693,0.00034107,0.0005808793,0.0002440314,0.03741785],"category_scores_gemma":[0.0001376206,0.0001835471,0.0002591323,0.0004987096,0.0002259907,0.0007298051,0.00063385,0.0006933312,0.007188028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004617733,"about_ca_system_score_gemma":0.0004249466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007195573,"about_ca_topic_score_gemma":0.001175833,"domain_scores_codex":[0.999772,0.00002422274,0.00001038595,0.00003183843,0.00004724768,0.0001144066],"domain_scores_gemma":[0.9999247,0.00000772123,0.00001006854,0.00001366987,0.00001454817,0.0000293827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001544274,0.0003266976,0.0008694052,0.0024844,0.0001243056,0.002443575,0.0007221093,0.00347906,0.7897389,0.06608634,0.04544137,0.08673967],"study_design_scores_gemma":[0.0001840401,0.003097739,0.004311206,0.0002345516,0.00008756867,0.001711795,0.0003258266,0.00137513,0.7253222,0.007323289,0.255863,0.0001635641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.4655772,0.01519296,0.01733201,0.001933669,0.003234451,0.0002512597,0.005868581,0.001214835,0.4893949],"genre_scores_gemma":[0.8860213,0.01489771,0.00282968,0.0005833836,0.000230934,0.00009835712,0.001931174,0.0001456696,0.09326196],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03741785,"threshold_uncertainty_score":0.1251752,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2222257188","doi":"10.1107/s1600536808001190","title":"5,7-Di-2-pyridyl-2,3-dihydrothieno[3,4-<i>b</i>][1,4]dioxine","year":2008,"lang":"en","type":"article","venue":"Acta Crystallographica Section E Structure Reports Online","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; Brock University","funders":"Natural Sciences and Engineering Research Council of Canada; Brock University; McMaster University","keywords":"Ring (chemistry); Chemistry; Thio-; Pyridine; Stereochemistry; Medicinal chemistry; Organic chemistry","authors":[{"name":"Brandon Djukic","is_ca":true},{"name":"L.E. Harrington","is_ca":true},{"name":"James F. Britten","is_ca":true},{"name":"Martin T. Lemaire","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01040511921899975,"gpt":0.2267148586143271,"spread":0.2163097393953273,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001123641,0.0001716661,0.0003376765,0.0001155626,0.0002176691,0.0001587391,0.0004171988,0.0001442531,0.00198608],"category_scores_gemma":[0.00006603973,0.0000955186,0.00007641627,0.0001869064,0.0001485878,0.0001330858,0.000135939,0.0002148793,0.0005884725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002878777,"about_ca_system_score_gemma":0.000283211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008684492,"about_ca_topic_score_gemma":0.002858362,"domain_scores_codex":[0.9999117,0.00001315326,0.000004569481,0.00001911428,0.00001416604,0.00003730489],"domain_scores_gemma":[0.999969,0.000002852267,0.00000535727,0.000004493262,0.00000576856,0.00001253976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006123103,0.00009398377,0.0004136036,0.0001961598,0.00001001707,0.0001916914,0.00005386015,0.0004830909,0.9899997,0.001451178,0.0004884403,0.006005928],"study_design_scores_gemma":[0.0001782218,0.00149006,0.003233259,0.0000120826,0.00001845702,0.0003634542,0.00005547824,0.0011971,0.9746416,0.0001946742,0.0185972,0.00001843737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722086,0.002443587,0.006581818,0.000153957,0.0001277434,0.0001452293,0.0008665289,0.0002051291,0.01726747],"genre_scores_gemma":[0.9891077,0.001102558,0.002667274,0.00006965209,0.00001198006,0.00005573698,0.000454043,0.00001886213,0.006512117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00198608,"threshold_uncertainty_score":0.00664413,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1850612168","doi":"10.1139/v2012-067","title":"A versatile method for the synthesis of γ-pyrones","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; University of Saskatchewan","keywords":"Chemistry; Aldol reaction; Triflic acid; Dithiane; Dithiolane; Synthon; Ketone; Organic chemistry; Adduct; Methylene; Combinatorial chemistry; Catalysis","authors":[{"name":"Garrison E. Beye","is_ca":true},{"name":"Athanasios Karagiannis","is_ca":true},{"name":"Alieh Kazemeini","is_ca":true},{"name":"Dale E. Ward","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01809944525322299,"gpt":0.2533921896951917,"spread":0.2352927444419687,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002416186,0.0006299525,0.0002331245,0.0005702054,0.0003244943,0.0002171022,0.000486128,0.0002718704,0.002381681],"category_scores_gemma":[0.0001915902,0.0003142414,0.0002678465,0.0002838991,0.0002526052,0.0004301034,0.000513172,0.001160323,0.001552512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002295194,"about_ca_system_score_gemma":0.0003780226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002520487,"about_ca_topic_score_gemma":0.0007704881,"domain_scores_codex":[0.9998274,0.00002166724,0.0000163445,0.00004425178,0.00005748494,0.00003289891],"domain_scores_gemma":[0.9999093,0.00001400589,0.00001913742,0.00002353307,0.00001804529,0.00001601691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004073513,0.00003402088,0.00007411535,0.0003187663,0.00001643047,0.0002907079,0.0001143546,0.0004729224,0.9685715,0.003366628,0.0004973821,0.02620248],"study_design_scores_gemma":[0.00002187049,0.0002706355,0.0003518128,0.00002929866,0.00001630293,0.0009934951,0.00002696122,0.0005804782,0.9559349,0.0006637331,0.04108576,0.00002481871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3364342,0.0176948,0.5922469,0.0005364798,0.0005832381,0.0009139703,0.001483509,0.001658485,0.04844842],"genre_scores_gemma":[0.8102558,0.0157559,0.1534966,0.0002493291,0.00009055439,0.0004992707,0.001144411,0.0001904498,0.01831764],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002381681,"threshold_uncertainty_score":0.007967532,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2952471338","doi":"10.1002/chin.201106139","title":"ChemInform Abstract: Synthesis of Substituted Indole from 2‐Aminobenzaldehyde Through [1,2]‐Aryl Shift.","year":2011,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Aryl; Indole test; Simple (philosophy); Combinatorial chemistry; Organic chemistry","authors":[{"name":"Patrick Levesque","is_ca":true},{"name":"Pierre‐André Fournier","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03259954182119512,"gpt":0.2339743842102276,"spread":0.2013748423890324,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001007869,0.0005200377,0.0001749064,0.0003995434,0.0002886989,0.0002127429,0.0005515279,0.0003274094,0.007571904],"category_scores_gemma":[0.0000810997,0.0002492525,0.0002089351,0.0002575498,0.0001411361,0.0002712102,0.0002457851,0.0004721545,0.003767115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000361901,"about_ca_system_score_gemma":0.0006995042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001021265,"about_ca_topic_score_gemma":0.002917177,"domain_scores_codex":[0.9999185,0.00000754363,0.000003844394,0.00001733674,0.0000277383,0.00002502679],"domain_scores_gemma":[0.9999635,0.000003860645,0.000008209655,0.000004316853,0.000007937373,0.00001212755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001543644,0.0001059407,0.0001517854,0.0005143092,0.00002271715,0.0005087116,0.00007705325,0.000420821,0.9531801,0.00301552,0.005679083,0.03616954],"study_design_scores_gemma":[0.00006805181,0.0003761741,0.001610002,0.00003276554,0.00002989844,0.000597537,0.00001642942,0.0006766143,0.9445484,0.0004031054,0.05161225,0.00002875895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5188186,0.02359367,0.1691891,0.002080391,0.00175372,0.001059701,0.01187897,0.007193803,0.264432],"genre_scores_gemma":[0.887866,0.01017624,0.04532689,0.0005992523,0.0001412446,0.0002811586,0.004530902,0.0002565359,0.05082181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007571904,"threshold_uncertainty_score":0.02533054,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W6921905342","doi":"10.1021/ol901264f.s001","title":"Intramolecular Pyridine Activation−Dearomatization Reaction: Highly Stereoselective Synthesis of Polysubstituted Indolizidines and Quinolizidines","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Stantec (Canada)","funders":"","keywords":"Intramolecular force; Pyridine; Stereoselectivity; Intramolecular reaction; Bicyclic molecule","authors":[],"retraction":null,"screen_n_in":null,"score":{"opus":0.01724852197327588,"gpt":0.2254896940876405,"spread":0.2082411721143646,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001327135,0.0005185464,0.0001825505,0.0001789703,0.0001795521,0.0001505572,0.00047339,0.0001786143,0.002399313],"category_scores_gemma":[0.00007441289,0.000107735,0.0001701657,0.000179764,0.0001706883,0.0003104024,0.0002895294,0.0004550727,0.0009605633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000222364,"about_ca_system_score_gemma":0.0002804932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004162087,"about_ca_topic_score_gemma":0.001051552,"domain_scores_codex":[0.999918,0.00000879143,0.000006340253,0.0000221027,0.00002142394,0.00002329756],"domain_scores_gemma":[0.9999778,0.000002814149,0.000005797798,0.000004672945,0.000003530976,0.000005321414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006466724,0.0000624605,0.0001592981,0.0001706031,0.00001499102,0.0004368746,0.0001292441,0.0004896009,0.9736021,0.001970134,0.0003232508,0.02257686],"study_design_scores_gemma":[0.00003113331,0.0005269821,0.001122022,0.000007666268,0.00001754005,0.0007890065,0.00002430225,0.0009610155,0.9831129,0.0002424811,0.0131473,0.0000176716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8853562,0.006559291,0.06014832,0.0002811092,0.000183477,0.0002791163,0.0009100752,0.0006111089,0.04567138],"genre_scores_gemma":[0.9756918,0.002605854,0.01340757,0.00005548285,0.00002891944,0.00006744922,0.0004147025,0.000047971,0.007680288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002399313,"threshold_uncertainty_score":0.00802654,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W7132966787","doi":"","title":"The Diels-Alder reaction of transient nitrosoguanidines: a new class of N-O heterodienophiles and a novel method for the synthesis of functionalized guanidines","year":2003,"lang":"","type":"dissertation","venue":"TSpace","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Yield (engineering); Regioselectivity; Intramolecular force; Simple (philosophy); Transient (computer programming); Reaction conditions","authors":[{"name":"Craig Miller","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03364063579454284,"gpt":0.3283307288374755,"spread":0.2946900930429326,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001110161,0.0002194301,0.0001148604,0.0001245885,0.0001483494,0.0002116501,0.0001369029,0.0001695924,0.001667276],"category_scores_gemma":[0.00004928569,0.0001219058,0.0001173062,0.00009033758,0.0001730725,0.0002434233,0.0001646914,0.0004129906,0.0004199776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551124,"about_ca_system_score_gemma":0.0003050617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002645774,"about_ca_topic_score_gemma":0.001131529,"domain_scores_codex":[0.9999605,0.000005018991,0.000002309224,0.00001024652,0.00001462032,0.000007211114],"domain_scores_gemma":[0.9999837,0.000003468885,0.000004262539,0.000001505788,0.000002865267,0.000004201965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003850184,0.00002749428,0.00009098157,0.0004401149,0.000009680556,0.0002084753,0.0002633299,0.0004759226,0.9505409,0.009920266,0.0008321304,0.03715225],"study_design_scores_gemma":[0.00001492854,0.0003551322,0.0006125417,0.00004598941,0.00001453335,0.0005163891,0.00006955236,0.000623139,0.8763455,0.001033517,0.1203562,0.000012529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7216008,0.08217826,0.1150389,0.001456642,0.0008200632,0.0003098282,0.0004253191,0.0003438698,0.07782644],"genre_scores_gemma":[0.7532348,0.08674895,0.05938005,0.0003967415,0.00016583,0.0001711754,0.0004263513,0.00007208579,0.09940394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001667276,"threshold_uncertainty_score":0.005577564,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W7024080090","doi":"","title":"A regioselective approach to trisubstituted 2 (or 6)-arylaminopyrimidine-5-carbaldehydes and their application in the synthesis of structurally and electronically unique G boolean AND C base precursors","year":2008,"lang":"en","type":"article","venue":"NPARC","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Regioselectivity; Base (topology); Boolean function; Substitution (logic); Key (lock)","authors":[],"retraction":null,"screen_n_in":null,"score":{"opus":0.01572300286161717,"gpt":0.2217893410827405,"spread":0.2060663382211234,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003004533,0.0004523624,0.0002123896,0.0003155226,0.0003346185,0.0002940449,0.001008187,0.0004376232,0.003186817],"category_scores_gemma":[0.0002846124,0.0002622816,0.0002633239,0.000259588,0.0003357124,0.0004119696,0.0004280595,0.0008744081,0.00117099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003734478,"about_ca_system_score_gemma":0.0006398655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009130855,"about_ca_topic_score_gemma":0.002405906,"domain_scores_codex":[0.9998156,0.0000387409,0.00001698578,0.0000353945,0.00004043096,0.00005283768],"domain_scores_gemma":[0.9998879,0.00002119884,0.00002640444,0.00002438362,0.00001914013,0.00002081056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003146524,0.0001820784,0.0002304043,0.0004911562,0.00002968048,0.001161764,0.0003695899,0.0009907497,0.9453791,0.0119411,0.001224337,0.03768534],"study_design_scores_gemma":[0.00004493543,0.0007142519,0.000469532,0.00001434607,0.00002015623,0.001080022,0.00003682502,0.0006906878,0.9834477,0.0004604616,0.01299127,0.00002982659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8224339,0.0064973,0.1063148,0.0007635456,0.0005905033,0.0008519746,0.0007356316,0.001169907,0.06064246],"genre_scores_gemma":[0.9593385,0.00295899,0.02677291,0.0001762712,0.0000582999,0.0001525641,0.000313302,0.00008445181,0.01014468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003186817,"threshold_uncertainty_score":0.01066101,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W7132973652","doi":"","title":"A new guanidinylation procedure for the preparation of functionalized guanidines and investigation towards the synthesis of cyclic quanidine compounds","year":2003,"lang":"","type":"dissertation","venue":"TSpace","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Guanidine; Alkylation; Halide; Alkyl; Palladium","authors":[{"name":"Philip Dean Ramsden","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03864292734327032,"gpt":0.3274736252216855,"spread":0.2888306978784152,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002278499,0.000459425,0.0002371832,0.0002676673,0.0003875445,0.0001976285,0.0002885346,0.0003015389,0.0034919],"category_scores_gemma":[0.0001516909,0.0002126818,0.000202366,0.0002502249,0.0001914465,0.000389698,0.0002411893,0.0008926517,0.00139905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002508656,"about_ca_system_score_gemma":0.0006490496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003414773,"about_ca_topic_score_gemma":0.001335879,"domain_scores_codex":[0.9998422,0.0000143314,0.00001267046,0.00004651063,0.0000645653,0.0000197722],"domain_scores_gemma":[0.9999335,0.0000144175,0.00001381241,0.000009355315,0.00001853291,0.00001041894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003082082,0.00003713399,0.0000870846,0.0005278416,0.000009017486,0.0002139599,0.0002224375,0.000159478,0.9602751,0.002148002,0.0008594941,0.03542961],"study_design_scores_gemma":[0.00002553973,0.0005300362,0.00117401,0.00005766608,0.00002148684,0.001440259,0.00005978897,0.0005280307,0.8704623,0.0005759695,0.1250903,0.00003464933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4362389,0.05358028,0.4226418,0.001981941,0.002004182,0.001652167,0.001770664,0.001329516,0.0788006],"genre_scores_gemma":[0.5163271,0.05024061,0.3469693,0.000751274,0.000237901,0.001013299,0.001639549,0.0002306135,0.0825902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0034919,"threshold_uncertainty_score":0.01168162,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4250396770","doi":"10.21203/rs.3.rs-898551/v1","title":"Highly Diastereoselective Cascade [5+1] Double Michael Reaction, a Route for The Synthesis of Spiro Thio-Oxindoles","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Iran National Science Foundation; McGill University; Sharif University of Technology; National Science Foundation","keywords":"Regioselectivity; Chemistry; Thio-; Selectivity; Catalysis; Combinatorial chemistry; Cascade; Docking (animal); Reaction conditions; Michael reaction; Organic chemistry; Chromatography","authors":[{"name":"Firouz Matloubi Moghaddam","is_ca":false},{"name":"Vahid Saberi","is_ca":false},{"name":"Ashkan Karimi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06796897492646402,"gpt":0.3632407901820279,"spread":0.2952718152555639,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002515739,0.0005008254,0.0002642613,0.0002734603,0.0001778669,0.0002120088,0.0003654024,0.0002759629,0.00178106],"category_scores_gemma":[0.0001253214,0.0001532521,0.0002166905,0.0001401354,0.0001597184,0.0002795463,0.0002953545,0.000457936,0.001088075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002580615,"about_ca_system_score_gemma":0.0003265083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003101974,"about_ca_topic_score_gemma":0.0008223903,"domain_scores_codex":[0.9998682,0.00002203182,0.000008912771,0.00003294955,0.0000275522,0.00004033887],"domain_scores_gemma":[0.9999604,0.000004609289,0.00001161231,0.000005239627,0.000005922938,0.00001220998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001579942,0.000133047,0.0004134443,0.000532466,0.00005332301,0.0009899624,0.0001738957,0.002138822,0.9489326,0.009110415,0.001296486,0.03606755],"study_design_scores_gemma":[0.00007279334,0.001298679,0.001588417,0.00003645525,0.00003905848,0.001997652,0.00005946842,0.003434019,0.9612013,0.001651117,0.02856181,0.00005933761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7594358,0.01346458,0.1800389,0.000598406,0.0004247462,0.0004163535,0.001580644,0.00119565,0.0428449],"genre_scores_gemma":[0.9628453,0.003964721,0.02579166,0.0001116524,0.00004228536,0.00007472076,0.0003934529,0.00004733867,0.006728862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00178106,"threshold_uncertainty_score":0.0059582,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2153271898","doi":"10.1002/chin.200125148","title":"ChemInform Abstract: Remarkable Synthesis of 2‐(Z)‐6‐(E)‐4H‐[1,4]‐Thiazepin‐5‐ones by Zwitterionic Rhodium‐Catalyzed Chemo‐ and Regioselective Cyclohydrocarbonylative Ring Expansion of Acetylenic Thiazoles.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Regioselectivity; Rhodium; Ring (chemistry); Catalysis; Combinatorial chemistry; Stereochemistry; Organic chemistry","authors":[{"name":"Bernard G. Van den Hoven","is_ca":true},{"name":"Howard Alper","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009728139643358398,"gpt":0.2239178924089062,"spread":0.2141897527655479,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001169877,0.0005969552,0.0002225774,0.0002449366,0.0001918336,0.0002439796,0.0004898114,0.0002914779,0.00748125],"category_scores_gemma":[0.0001105035,0.0001780435,0.0002081358,0.0002622496,0.0001665592,0.0003690186,0.0002804066,0.0004338705,0.002923086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002929338,"about_ca_system_score_gemma":0.0005082379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009140449,"about_ca_topic_score_gemma":0.001538819,"domain_scores_codex":[0.9999329,0.000008001693,0.00000443567,0.00001512542,0.00001427596,0.00002524162],"domain_scores_gemma":[0.9999676,0.000003632896,0.000008601218,0.000004809667,0.000004849951,0.0000105303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000401394,0.0001121723,0.0001378121,0.0008140443,0.00004687124,0.0007946597,0.0001425707,0.001297272,0.9409285,0.003936869,0.007306154,0.04408165],"study_design_scores_gemma":[0.0001569086,0.0008120318,0.001354493,0.00002712131,0.00004795469,0.0006923996,0.00002303676,0.0009645552,0.9542518,0.0005678813,0.04106336,0.00003846461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7559358,0.02006582,0.05691485,0.001378875,0.001165885,0.0006111295,0.009310968,0.001998016,0.1526186],"genre_scores_gemma":[0.9249759,0.01049473,0.01318149,0.0002929495,0.0001580323,0.0001469095,0.002921965,0.0001814259,0.04764672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00748125,"threshold_uncertainty_score":0.02502728,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2950023042","doi":"10.1002/chin.201528170","title":"ChemInform Abstract: A Cascade Synthesis of Aminohydantoins Using in situ‐Generated N‐Substituted Isocyanates.","year":2015,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Cascade; In situ; Combinatorial chemistry; Simple (philosophy); Organic chemistry; Chromatography","authors":[{"name":"Christian Clavette","is_ca":true},{"name":"Kyle Leckett","is_ca":true},{"name":"André M. Beauchemin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03852280276743452,"gpt":0.2650221470566769,"spread":0.2264993442892423,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001182402,0.0005894498,0.0001750574,0.0002893365,0.000211342,0.0002580832,0.000426812,0.0003000071,0.009608136],"category_scores_gemma":[0.00008353937,0.000239309,0.0001559107,0.0001861038,0.00020222,0.000306803,0.000329325,0.0005579178,0.002790112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003693309,"about_ca_system_score_gemma":0.0005598787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000654862,"about_ca_topic_score_gemma":0.001300694,"domain_scores_codex":[0.9999152,0.00001024164,0.000003944393,0.00002416372,0.00002603516,0.00002038013],"domain_scores_gemma":[0.999963,0.000004580545,0.000008528663,0.000006425726,0.00000658132,0.00001076347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002026949,0.0001122888,0.0001641135,0.0005125132,0.00002394182,0.0004092283,0.00009831051,0.0005750193,0.9492866,0.007207606,0.005175218,0.0362325],"study_design_scores_gemma":[0.00004531051,0.0002540084,0.0004456865,0.00001646812,0.00001745805,0.0003437922,0.00001404294,0.0005884841,0.9676381,0.0003306933,0.030294,0.00001194319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.471991,0.007329764,0.1450834,0.00114199,0.001003042,0.001111987,0.005088791,0.004284037,0.3629659],"genre_scores_gemma":[0.9110479,0.005552593,0.0386829,0.00030859,0.00009654386,0.0001800717,0.001697364,0.0001912114,0.04224284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009608136,"threshold_uncertainty_score":0.03214246,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4409636196","doi":"10.1158/1538-7445.am2025-5641","title":"Abstract 5641: Role of ceramide synthase 2 in drug-induced ER-stress, Ca2+ release and apoptosis in triple-negative breast cancer cells","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Triple-negative breast cancer; Ceramide; Apoptosis; Cancer; Breast cancer; Cancer research; Drug; Medicine; Internal medicine; Chemistry; Pharmacology; Biochemistry","authors":[{"name":"Hissah Alatawi","is_ca":false},{"name":"Haritha Nair","is_ca":false},{"name":"G Buchman Timothy.","is_ca":false},{"name":"Sharma Arun","is_ca":true},{"name":"Satya Narayan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02583549614295738,"gpt":0.342715586553315,"spread":0.3168800904103576,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001396192,0.0002899811,0.0004819446,0.0002365874,0.0002513897,0.0002962295,0.0002033062,0.000426831,0.00193929],"category_scores_gemma":[0.00008117204,0.0001194846,0.0002966622,0.0002577507,0.0001285289,0.0002188211,0.0001995024,0.0005720148,0.0006314622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003399458,"about_ca_system_score_gemma":0.0003029087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007459905,"about_ca_topic_score_gemma":0.0006713188,"domain_scores_codex":[0.9998902,0.00001448281,0.00001513386,0.00001924435,0.00003481155,0.00002606419],"domain_scores_gemma":[0.999969,0.000004186847,0.000005455852,0.000003526849,0.000006489257,0.00001140707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001053212,0.0001009946,0.0004935006,0.0002287912,0.00001965962,0.0004017907,0.00003902958,0.00008801174,0.9927206,0.0001507413,0.0004233271,0.004280336],"study_design_scores_gemma":[0.0003211707,0.001480241,0.02408984,0.00004254981,0.00006745393,0.001705171,0.0001672366,0.002189188,0.957844,0.000338138,0.01172953,0.00002539963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9695258,0.01993148,0.001328934,0.0008675365,0.0002759181,0.0001038904,0.002088526,0.00008529767,0.005792563],"genre_scores_gemma":[0.9868268,0.004376645,0.0009308703,0.000214438,0.00004229842,0.0001222445,0.001916317,0.000009039593,0.00556123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00193929,"threshold_uncertainty_score":0.006487608,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}