{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":746,"total_is_capped":false,"direct_labels_cover":1,"predictions_cover":746,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"9a0bf038503e","filters":{"topic":"TGF-β signaling in diseases"}},"results":[{"id":"W2009396278","doi":"10.1016/s1097-2765(00)00134-9","title":"Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation","year":2000,"lang":"en","type":"article","venue":"Molecular Cell","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1332,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Ubiquitin ligase; Ubiquitin; Biology; Receptor; Ubiquitin-Protein Ligases; Signal transducing adaptor protein; Cell biology; Proteolysis; Transforming growth factor; Signal transduction; Molecular biology; Biochemistry; Gene; Enzyme","authors":[{"name":"Peter A. Kavsak","is_ca":true},{"name":"Richele K. Rasmussen","is_ca":true},{"name":"Carrie G. Causing","is_ca":true},{"name":"Shirin Bonni","is_ca":true},{"name":"Haitao Zhu","is_ca":false},{"name":"Gerald H. Thomsen","is_ca":false},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01127296510522331,"gpt":0.2482977596931472,"spread":0.2370247945879239,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002099955,0.0002383007,0.0001415483,0.00005196837,0.0001724236,0.00007890781,0.0004509455,0.0001368088,0.0001823257],"category_scores_gemma":[0.00006745265,0.0002050044,0.0001460432,0.0001260143,0.00003079711,0.000007361588,0.00007837905,0.00006577133,0.0001344489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002639998,"about_ca_system_score_gemma":0.00008169555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002522656,"about_ca_topic_score_gemma":0.00003360206,"domain_scores_codex":[0.9985685,0.00006965824,0.0002117155,0.000528632,0.0002038288,0.0004177083],"domain_scores_gemma":[0.9988815,0.00001593275,0.00005402149,0.0006709254,0.00009090905,0.0002867054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002405303,0.0001428235,0.000110861,0.00002164959,0.00002434294,0.00000408113,0.0001778147,0.000676515,0.9700029,0.00001613452,0.0108,0.01778229],"study_design_scores_gemma":[0.0002901775,0.0003780372,0.0001193774,0.00000958136,0.00002247228,0.00000120406,0.00004150975,0.0000359805,0.7056301,0.00003186294,0.293223,0.0002166501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839659,0.0005402052,0.01287686,0.0005421269,0.0001088947,0.000880306,0.00009983832,0.00003805197,0.0009478549],"genre_scores_gemma":[0.9829085,0.00001759666,0.009008145,0.003762107,0.0002129957,0.0002968029,0.0008110033,0.00007543612,0.00290735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.282423,"threshold_uncertainty_score":0.8359838,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1994738588","doi":"10.1126/science.1071809","title":"Signal Transduction by the TGF-β Superfamily","year":2002,"lang":"en","type":"review","venue":"Science","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1270,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"SMAD; R-SMAD; Signal transduction; Cell biology; Transforming growth factor; Biology; Transmembrane protein; Transforming growth factor beta; Receptor; Intracellular; TGF beta signaling pathway; Cell surface receptor; ACVRL1; Endoglin; TGF alpha; Genetics; Growth factor","authors":[{"name":"Liliana Attisano","is_ca":false},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03329286762415178,"gpt":0.3078014522742157,"spread":0.2745085846500639,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003673328,0.0002296794,0.000267342,0.00004951903,0.0003026346,0.00008597603,0.001040781,0.0001431194,0.0001351606],"category_scores_gemma":[0.00006268005,0.0001488423,0.0002041846,0.0003664764,0.0007791211,0.000005352223,0.00008514206,0.0001505827,0.00008317681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002938682,"about_ca_system_score_gemma":0.0004056854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003060783,"about_ca_topic_score_gemma":9.728249e-7,"domain_scores_codex":[0.9984285,0.00007984698,0.000237871,0.0005861768,0.0003493651,0.0003182885],"domain_scores_gemma":[0.9992086,0.0000190155,0.00009359505,0.0005186586,0.00006044938,0.00009962861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002053951,0.00004787333,0.000001835107,0.0005064107,0.00002296068,0.000001166903,0.00002325615,0.000004910789,0.01297353,0.000006007097,0.008192662,0.9782174],"study_design_scores_gemma":[0.00003756551,0.00004630482,0.000001760539,0.0003000044,0.00008137873,0.00002512506,0.000008437562,0.000004100274,0.004050182,0.000003886986,0.9952424,0.0001988897],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002982212,0.9984587,0.0001772206,0.00001542386,0.000268915,0.0002523373,0.00004606634,0.00001540035,0.0004676562],"genre_scores_gemma":[0.0009048281,0.9972125,0.00005792784,0.0000679296,0.0003078971,0.00004925692,0.00007163906,0.00002317767,0.001304859],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9870497,"threshold_uncertainty_score":0.6069613,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2028919524","doi":"10.1126/science.1105718","title":"Regulation of the Polarity Protein Par6 by TGFß Receptors Controls Epithelial Cell Plasticity","year":2005,"lang":"en","type":"article","venue":"Science","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":867,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Cell biology; Epithelial–mesenchymal transition; Ubiquitin ligase; Biology; Cell polarity; Morphogenesis; Regulator; Mesenchyme; Transforming growth factor; Cell; Mesenchymal stem cell; Ubiquitin; Downregulation and upregulation; Biochemistry","authors":[{"name":"Barish Ozdamar","is_ca":true},{"name":"Rohit Bose","is_ca":true},{"name":"Miriam Barrios‐Rodiles","is_ca":true},{"name":"Hongrui Wang","is_ca":true},{"name":"Yue Zhang","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00432439228698253,"gpt":0.2163730258819412,"spread":0.2120486335949586,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002493843,0.00006782491,0.00006075367,0.00001477557,0.0001428989,0.00001832416,0.0003709281,0.00004846978,0.00002341411],"category_scores_gemma":[0.0003146833,0.00004989449,0.00003927906,0.0001281243,0.0004793545,0.000007780664,0.00009356759,0.00004614006,0.000005775154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001719159,"about_ca_system_score_gemma":0.000190872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001261937,"about_ca_topic_score_gemma":0.00001021612,"domain_scores_codex":[0.9991876,0.00004321001,0.000132825,0.000225493,0.0002467574,0.0001640386],"domain_scores_gemma":[0.9995252,0.00001018391,0.0001027384,0.0002208394,0.00008521033,0.00005586154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002582247,0.00004877461,0.001868104,0.00000428026,0.000001476616,1.435074e-8,0.00001832331,0.0001359978,0.9972069,0.00001939179,0.0001497157,0.0005211657],"study_design_scores_gemma":[0.0001963347,0.00004409091,0.01508511,0.000008468777,0.000004099232,2.765137e-7,0.000006574987,0.0001607645,0.9754165,0.00003998079,0.008974075,0.00006367386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985453,0.0001423213,0.0006492102,0.0001176511,0.00008075943,0.0001918813,0.00002992003,0.000006343076,0.0002366293],"genre_scores_gemma":[0.9987813,0.000001174979,0.0005797225,0.00006340397,0.00008829044,0.000007608917,0.000004287553,0.000004203297,0.0004699685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02179039,"threshold_uncertainty_score":0.2034638,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2047259732","doi":"10.1002/wdev.86","title":"The TGFbeta Superfamily Signaling Pathway","year":2012,"lang":"en","type":"review","venue":"Wiley Interdisciplinary Reviews Developmental Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":554,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell biology; SMAD; Growth differentiation factor; Signal transduction; Morphogenesis; Bone morphogenetic protein; BMPR2; Decapentaplegic; R-SMAD; Transforming growth factor; Transforming growth factor beta; Stem cell; Transcription factor; Genetics; Gene; Endoglin","authors":[{"name":"Alexander Weiß","is_ca":true},{"name":"Liliana Attisano","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06362887582068782,"gpt":0.3483737385697017,"spread":0.2847448627490139,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001368167,0.001175435,0.002070179,0.0001284824,0.0008294853,0.00008645246,0.001809718,0.0008269509,0.0001544953],"category_scores_gemma":[0.0001422816,0.000723777,0.0012215,0.0002651284,0.0005195945,0.00001187417,0.00344284,0.0005880605,0.001442875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002124788,"about_ca_system_score_gemma":0.0006885279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001584226,"about_ca_topic_score_gemma":0.00001719846,"domain_scores_codex":[0.9944184,0.001123224,0.002013895,0.001170639,0.0001774075,0.001096415],"domain_scores_gemma":[0.9975588,0.0002230749,0.0008167475,0.001012238,0.00007482919,0.0003143495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002773991,0.00009699745,0.00005260787,0.00280098,0.0004323074,0.000005381445,0.0000986478,1.709698e-7,0.001189114,0.00002597224,0.005187111,0.990083],"study_design_scores_gemma":[0.0001306979,0.000158236,0.000002818669,0.005736067,0.0003526626,0.0002189436,0.00007376786,2.284143e-7,0.0003910624,0.00002698874,0.9919789,0.0009295744],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001533654,0.9953101,0.0001093684,0.00001750759,0.001544417,0.001614331,0.0001469614,0.00004896884,0.001054953],"genre_scores_gemma":[0.0002364113,0.9914213,0.001052845,0.0001252432,0.001340467,0.001104915,0.003446834,0.0001539567,0.001118022],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9891534,"threshold_uncertainty_score":0.9995213,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2033887719","doi":"10.1016/s0955-0674(99)00081-2","title":"Smads as transcriptional co-modulators","year":2000,"lang":"en","type":"review","venue":"Current Opinion in Cell Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":521,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Biology; SMAD; Repressor; Cell biology; R-SMAD; Nucleus; Transforming growth factor; Transcriptional regulation; Transcription factor; Gene; Genetics; Stem cell; Endoglin","authors":[{"name":"Liliana Attisano","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07569489515038297,"gpt":0.4038422095131525,"spread":0.3281473143627695,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000172449,0.0005420659,0.0008779709,0.0002370435,0.00006320533,0.00001879431,0.000556228,0.0008068985,0.0004812787],"category_scores_gemma":[0.00003268657,0.0004983119,0.000533081,0.0001630008,0.0001944856,0.000002660554,0.00007113515,0.0004094012,0.0003815159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005341997,"about_ca_system_score_gemma":0.000616523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004716285,"about_ca_topic_score_gemma":8.486002e-7,"domain_scores_codex":[0.9973596,0.0003654823,0.0007683387,0.0009228691,0.0001202086,0.0004634726],"domain_scores_gemma":[0.9990208,0.00004772554,0.0002330006,0.0005124133,0.00003293161,0.0001531728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004648312,0.0004410993,0.0001674148,0.008277091,0.00008131548,0.00000107289,0.00001809339,0.0000157071,0.0003067637,0.0001564385,0.006495595,0.9839929],"study_design_scores_gemma":[0.0003541081,0.0001466125,0.00001178209,0.00174184,0.00005212464,0.00001102888,0.000002392844,0.000001475748,0.0001468695,0.00005505541,0.9969659,0.0005108479],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003498525,0.9939637,0.00003777801,0.000005210547,0.003936786,0.0005040288,0.0003528433,0.00002613965,0.0008236224],"genre_scores_gemma":[0.0003325394,0.9849826,0.00003450413,0.00001734585,0.001393896,0.0002033736,0.01277196,0.00006201165,0.0002017359],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9904703,"threshold_uncertainty_score":0.9997469,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2093271566","doi":"10.1016/j.cellsig.2003.08.011","title":"Signal transduction of bone morphogenetic protein receptors","year":2003,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":515,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Bone morphogenetic protein; Crosstalk; BMPR2; Signal transduction; SMAD; Bone morphogenetic protein receptor; Cell biology; Biology; Receptor; Bone morphogenetic protein 5; Bone morphogenetic protein 7; Genetics","authors":[{"name":"Anja Nohe","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02591716545969939,"gpt":0.2623711255416749,"spread":0.2364539600819755,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005320989,0.0006353828,0.001253116,0.0002019148,0.000122063,0.00003002859,0.0003891703,0.0006896132,0.0004631251],"category_scores_gemma":[0.00005461877,0.0006328986,0.0009440706,0.0002820469,0.0001513753,0.000003928711,0.00005635029,0.00036789,0.00004038058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000427955,"about_ca_system_score_gemma":0.0005271307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000444505,"about_ca_topic_score_gemma":0.000001036713,"domain_scores_codex":[0.9967198,0.0005136341,0.001113996,0.0008492099,0.0003620056,0.0004413773],"domain_scores_gemma":[0.9984019,0.00003008224,0.0006758294,0.0005773391,0.0001369673,0.0001778421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003815584,0.0002586955,0.000001595516,0.0155746,0.0005291571,0.00002522187,0.00003465268,0.000335518,0.7651668,0.00002020235,0.0002108379,0.2178046],"study_design_scores_gemma":[0.0001588384,0.0001387648,2.959808e-8,0.003400663,0.0005127251,0.00001610965,0.00001021391,0.000004478446,0.3300669,0.0000119917,0.6651868,0.0004924483],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002836974,0.9841174,0.01154397,9.656711e-7,0.000263757,0.001036998,0.00003752173,0.00002768961,0.0001346502],"genre_scores_gemma":[0.004292795,0.9898297,0.002437731,0.000008680535,0.0005751778,0.0002207384,0.00111991,0.0002215828,0.00129366],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6649759,"threshold_uncertainty_score":0.9996122,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2997221406","doi":"10.1016/j.semcdb.2019.12.010","title":"TGF-β1 – A truly transforming growth factor in fibrosis and immunity","year":2019,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":454,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Fibrosis; Extracellular matrix; Transforming growth factor; Cytokine; Biology; Immunology; Immunity; Cell biology; Growth factor; Receptor; Transforming growth factor beta; Cancer research; Medicine; Pathology","authors":[{"name":"Monika Lodyga","is_ca":true},{"name":"Boris Hinz","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02049711860749236,"gpt":0.2793200452306517,"spread":0.2588229266231593,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001766961,0.0004378564,0.000868445,0.0002044377,0.000057876,0.0000186274,0.0002342422,0.0006490098,0.00002301631],"category_scores_gemma":[0.00005209209,0.0003852555,0.0001079783,0.0001391053,0.0001590808,0.000005747477,0.0002651648,0.0002814925,0.000009816762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006699112,"about_ca_system_score_gemma":0.0003351734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004885884,"about_ca_topic_score_gemma":0.00005449545,"domain_scores_codex":[0.9982266,0.0001624343,0.0005345226,0.0006331799,0.00005622872,0.0003870544],"domain_scores_gemma":[0.9994895,0.0001225495,0.0001248886,0.0001591695,0.00001456794,0.00008930085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001138373,0.0001945024,0.01616678,0.01152833,0.0001091963,0.00002393468,0.0008160152,1.48651e-7,0.01857649,0.000009130676,0.0001204008,0.9523413],"study_design_scores_gemma":[0.001413079,0.0004762587,0.0009957235,0.006758789,0.0001170981,0.0001479238,0.0005516526,0.000001079139,0.01775458,0.00006370089,0.970175,0.001545161],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1976353,0.8013221,0.000004402389,0.000002489703,0.00009446132,0.0003935855,0.0001042786,0.000006835559,0.0004365719],"genre_scores_gemma":[0.02636622,0.9717458,0.0007765457,0.00003681719,0.00003059228,0.00007371644,0.0007211795,0.00003630381,0.0002128523],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9700546,"threshold_uncertainty_score":0.9998599,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2059030354","doi":"10.1073/pnas.150152697","title":"Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-β and Wnt pathways","year":2000,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":444,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Enhancer; Wnt signaling pathway; Transcription factor; Biology; SMAD; Transforming growth factor; Cell biology; Signal transduction; Molecular biology; Genetics; Gene","authors":[{"name":"Étienne Labbé","is_ca":true},{"name":"Ainhoa Letamendı́a","is_ca":true},{"name":"Liliana Attisano","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01718407824465438,"gpt":0.242371109326331,"spread":0.2251870310816767,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003666164,0.0001205024,0.0001456742,0.00006055322,0.0001578744,0.00002660198,0.0003657194,0.0001003658,0.00003234427],"category_scores_gemma":[0.0001265568,0.00007053246,0.00004580177,0.0002891794,0.0003463118,0.00004823005,0.00002989544,0.00009277261,2.412707e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003996348,"about_ca_system_score_gemma":0.0000603543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005579176,"about_ca_topic_score_gemma":3.182606e-7,"domain_scores_codex":[0.9986342,0.00001423121,0.0002880413,0.0002409603,0.0006632,0.0001593654],"domain_scores_gemma":[0.9993114,0.0001217043,0.0003192746,0.000009066249,0.0002082451,0.00003035176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003600496,0.00003622378,0.02358332,0.00003422047,0.00002087139,3.113075e-9,0.0007793983,0.00005432958,0.9750743,0.00008622222,0.00005655796,0.0002385337],"study_design_scores_gemma":[0.0002741808,0.00008106409,0.01077719,0.00006488302,0.000007665773,8.813275e-7,0.0003427524,0.0000337601,0.9880782,0.0001701021,0.00007758493,0.00009168094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998404,0.0008159503,0.000002979973,0.0002001622,0.000008005792,0.0001752133,0.0001318726,0.000003550177,0.0002582308],"genre_scores_gemma":[0.9995064,0.0002135083,0.0001084254,0.00003075354,0.00003969246,0.00001161673,0.000001592058,0.000006255944,0.00008174004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01300394,"threshold_uncertainty_score":0.287623,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2150091603","doi":"10.1073/pnas.0932636100","title":"Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":427,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre","funders":"National Center for Research Resources; National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center; Damon Runyon Cancer Research Foundation; Howard Hughes Medical Institute","keywords":"Cancer research; Mammary tumor; Extravasation; Carcinogenesis; Metastasis; Transforming growth factor; Transforming growth factor beta; Biology; ACVRL1; Signal transduction; Endocrinology; Internal medicine; Endoglin; Medicine; Breast cancer; Cancer; Immunology; Cell biology","authors":[{"name":"Peter M. Siegel","is_ca":true},{"name":"Weiping Shu","is_ca":true},{"name":"Robert D. Cardiff","is_ca":true},{"name":"William J. Muller","is_ca":true},{"name":"Joan Massagué","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03639651933287697,"gpt":0.2806454038550757,"spread":0.2442488845221987,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009656323,0.0001550337,0.0001674484,0.0001214927,0.0002757658,0.0000319407,0.0007470848,0.0001008341,0.00001011077],"category_scores_gemma":[0.0006681115,0.0001166777,0.0001574517,0.0004967025,0.0002358352,0.0000656521,0.00008671109,0.0001070277,4.327528e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000019521,"about_ca_system_score_gemma":0.0001194364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000259014,"about_ca_topic_score_gemma":3.752115e-8,"domain_scores_codex":[0.9982154,0.00001979944,0.0003846399,0.0003688865,0.000770538,0.0002406701],"domain_scores_gemma":[0.9992309,0.00004803689,0.0003492009,0.00001531409,0.0002906561,0.00006587771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001072072,0.00006225027,0.005036746,0.00009973998,0.00003245007,2.349416e-8,0.0000980261,0.0000322088,0.9927423,0.0014708,0.00002164853,0.0003930917],"study_design_scores_gemma":[0.0001013897,0.0000619539,0.004418402,0.00006504909,0.00002035309,0.00001518147,0.0001480819,0.00008344575,0.9927512,0.002092087,0.0001068228,0.0001360197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977315,0.0004220448,0.00001502127,0.0002398703,0.00002152046,0.0002153645,0.00001939951,0.00001253605,0.001322738],"genre_scores_gemma":[0.9976012,0.00001738669,0.002155708,0.00009470477,0.00007120345,0.00001980378,7.145573e-7,0.00001062686,0.00002868839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002140686,"threshold_uncertainty_score":0.475798,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2025083720","doi":"10.1038/labinvest.3700669","title":"Pathobiology of transforming growth factor β in cancer, fibrosis and immunologic disease, and therapeutic considerations","year":2007,"lang":"en","type":"review","venue":"Laboratory Investigation","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":421,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Cancer Institute; Krembil Foundation; Ontario Institute for Cancer Research; Canadian Diabetes Association","keywords":"Medicine; Immunology; Cancer research; Cytokine; Fibrosis; Immune system; Transforming growth factor beta; Cancer; Angiogenesis; Transforming growth factor; Pathology; Internal medicine","authors":[{"name":"Gérald J. Prud’homme","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04959151117280902,"gpt":0.3194207341682454,"spread":0.2698292229954364,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001229785,0.0002342046,0.0004433834,0.0001240738,0.0000578643,0.00001549778,0.00006419058,0.0003051765,0.000007576783],"category_scores_gemma":[0.0001472213,0.0002115986,0.00005238442,0.0001607427,0.0003130635,0.000006815936,0.0000286186,0.0001234229,3.667958e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002424976,"about_ca_system_score_gemma":0.0005863118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001751218,"about_ca_topic_score_gemma":0.00004740253,"domain_scores_codex":[0.998831,0.0002014707,0.0004169522,0.000336802,0.00006156027,0.0001521982],"domain_scores_gemma":[0.9993423,0.00009150834,0.0002165504,0.0001617958,0.00009720336,0.00009063213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001553822,0.0003079172,0.05797956,0.04732681,0.001127448,0.00003036462,0.001235225,0.00002456056,0.2780422,0.003187991,0.000132603,0.61045],"study_design_scores_gemma":[0.003920399,0.001606276,0.07712332,0.03186357,0.004210396,0.0000453175,0.0003743741,0.0000423626,0.1287396,0.006498426,0.7402543,0.005321656],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1704961,0.8286328,0.00001381189,0.00001239513,0.0000474188,0.0003494826,0.0004360683,0.000009151891,0.000002784035],"genre_scores_gemma":[0.08528811,0.9139906,0.0001640593,0.000104543,0.0000512191,0.0001128833,0.0002590314,0.00002502125,0.000004503239],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7401217,"threshold_uncertainty_score":0.862874,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2082429467","doi":"10.1016/s0092-8674(00)81556-1","title":"Regulation of Smad Activity","year":2000,"lang":"en","type":"review","venue":"Cell","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":419,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"SMAD; Biology; Receptor; Signal transduction; Cell biology; Genetics","authors":[{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02415006552055851,"gpt":0.2945461893870074,"spread":0.2703961238664489,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004883188,0.0001584793,0.0003652594,0.00003218787,0.00001812448,0.000005312178,0.0001593379,0.000251903,0.0001119897],"category_scores_gemma":[0.00001298691,0.0001453185,0.0002480171,0.00005083621,0.00003698295,7.477121e-7,0.00004140465,0.00006131834,0.00003769112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009288419,"about_ca_system_score_gemma":0.0001698646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002447,"about_ca_topic_score_gemma":5.833073e-7,"domain_scores_codex":[0.9993345,0.00006806952,0.0001827003,0.0002409833,0.00007307412,0.0001007409],"domain_scores_gemma":[0.9993508,0.00001226537,0.0001820149,0.0003946344,0.00002145208,0.00003876693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001195015,0.00009450802,0.000001551565,0.006135204,0.00004083182,6.967439e-7,0.000003760207,0.000006163296,0.00829001,7.263332e-7,0.001391242,0.9840233],"study_design_scores_gemma":[0.00005626589,0.00002996779,0.000009988957,0.0005912105,0.0001470186,0.00000143004,3.027331e-7,7.723489e-7,0.03541569,0.000004090295,0.9636067,0.0001365471],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001075829,0.9942775,0.00004268228,4.255919e-7,0.00006120765,0.0001655698,0.00003002668,0.000007098437,0.004339663],"genre_scores_gemma":[0.002835714,0.9935224,0.00009756702,0.000003939218,0.0001655348,0.00001477795,0.0003984935,0.00002996566,0.002931621],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9838868,"threshold_uncertainty_score":0.5925916,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2797460017","doi":"10.1038/s41413-017-0005-4","title":"Transforming growth factor-β in stem cells and tissue homeostasis","year":2018,"lang":"en","type":"article","venue":"Bone Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":398,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Sichuan University; West China Hospital, Sichuan University; Department of Science and Technology of Sichuan Province; National Natural Science Foundation of China; York University","keywords":"Context (archaeology); Stem cell; Biology; Extracellular matrix; Progenitor cell; Homeostasis; Transforming growth factor; Regeneration (biology); Cell biology; Neuroscience; Immunology","authors":[{"name":"Xin Xu","is_ca":false},{"name":"Liwei Zheng","is_ca":false},{"name":"Quan Yuan","is_ca":false},{"name":"Gehua Zhen","is_ca":false},{"name":"Janet L. Crane","is_ca":false},{"name":"Xuedong Zhou","is_ca":false},{"name":"Xu Cao","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04736795356684593,"gpt":0.348846968881362,"spread":0.3014790153145161,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003888345,0.00008926544,0.0001028032,0.0001280399,0.0001014399,0.00003724899,0.0001386973,0.000104487,0.00003708557],"category_scores_gemma":[0.00004246899,0.0000863028,0.00002130348,0.0001641381,0.0002078047,0.00000459748,0.0001012574,0.0001190372,0.00003286026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001830431,"about_ca_system_score_gemma":0.0001027862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000927727,"about_ca_topic_score_gemma":0.0001251364,"domain_scores_codex":[0.998827,0.00011325,0.0001396648,0.0003035153,0.0002452659,0.0003713192],"domain_scores_gemma":[0.9994956,0.00003716232,0.00001433366,0.0002021809,0.0001306523,0.0001201324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007902861,0.00005049105,0.002880658,0.0000548168,0.00001034536,0.0000132349,0.0002161233,3.18048e-7,0.9704467,0.00002708218,0.0006184916,0.02560269],"study_design_scores_gemma":[0.0003099143,0.0002603849,0.002478299,0.00002546096,0.000001788223,0.000003785829,0.000137707,0.000005737293,0.9747677,0.00003748364,0.02186734,0.0001043982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965275,0.002464734,0.0001214502,0.00007194909,0.00002827682,0.0002045082,0.00002700457,0.000008476012,0.0005460961],"genre_scores_gemma":[0.9987916,0.0002713291,0.0001245139,0.00001719107,0.0001525942,0.00001992274,0.000008884625,0.0000196414,0.0005943728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02549829,"threshold_uncertainty_score":0.3519326,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2099137652","doi":"10.1161/atvbaha.109.189522","title":"Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus","year":2009,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":383,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Allele; Biology; Locus (genetics); Gene; Genetics; Enhancer; Gene expression; Genome-wide association study; Cancer research; Single-nucleotide polymorphism; Genotype","authors":[{"name":"Olga Jarinova","is_ca":true},{"name":"Alexandre F.R. Stewart","is_ca":true},{"name":"Robert Roberts","is_ca":true},{"name":"George A. Wells","is_ca":true},{"name":"Paulina Lau","is_ca":true},{"name":"Thet Naing","is_ca":true},{"name":"Christine Buerki","is_ca":true},{"name":"Bradley W. McLean","is_ca":true},{"name":"Richard Cook","is_ca":true},{"name":"Joel S. Parker","is_ca":true},{"name":"Ruth McPherson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01738629590450444,"gpt":0.2446808908834206,"spread":0.2272945949789162,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002021175,0.000248441,0.000400274,0.0001067355,0.0002333415,0.00002323879,0.0002596833,0.000159654,0.00009235426],"category_scores_gemma":[0.00007094384,0.0001859087,0.0005724619,0.000307805,0.0003343293,0.000008345638,0.0001103661,0.00009443078,0.000004964616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001242439,"about_ca_system_score_gemma":0.00006077361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001294666,"about_ca_topic_score_gemma":0.00002679924,"domain_scores_codex":[0.9983822,0.0002426466,0.0003684954,0.0005698176,0.000150106,0.0002867404],"domain_scores_gemma":[0.9987596,0.00002982241,0.0002070632,0.0007656176,0.00008064684,0.0001572638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000167759,0.0002270946,0.4624562,0.000007753862,0.001615494,5.218595e-8,0.00003817114,0.0001834374,0.5346173,0.00007280364,0.0002034105,0.000561533],"study_design_scores_gemma":[0.0004795369,0.0002299237,0.9928896,0.00002138512,0.001444274,2.992747e-7,0.00002223289,0.0001153006,0.003633153,0.00008399086,0.0008544812,0.0002258014],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978307,0.0007257388,0.0007251313,0.0001907275,0.000143206,0.000177882,0.0001663971,0.00001835021,0.00002190091],"genre_scores_gemma":[0.9977311,0.001216572,0.00008254458,0.0005763576,0.0001142145,0.00002241116,0.0002338402,0.00001553196,0.000007440851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5309841,"threshold_uncertainty_score":0.7581138,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2037787006","doi":"10.1038/ncb1113","title":"PKB/Akt modulates TGF-β signalling through a direct interaction with Smad3","year":2004,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":366,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Protein kinase B; Cell biology; PI3K/AKT/mTOR pathway; Signal transduction; AKT1; Transforming growth factor; Activator (genetics); Phosphorylation; Biology; Growth factor; Kinase; Transcription factor; Chemistry; Biochemistry; Receptor; Gene","authors":[{"name":"Ingrid Remy","is_ca":true},{"name":"Annie Montmarquette","is_ca":true},{"name":"Stephen W. Michnick","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005687106103401496,"gpt":0.2496104459186818,"spread":0.2439233398152803,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008200667,0.0002602699,0.0002128403,0.00004877749,0.0001061534,0.00002276951,0.0002438262,0.0006519358,0.00003559047],"category_scores_gemma":[0.00006668941,0.0002061898,0.0001014485,0.000115142,0.000122817,0.000007806366,0.00007822033,0.0003913377,0.00002749937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003626836,"about_ca_system_score_gemma":0.0001108901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003619974,"about_ca_topic_score_gemma":0.00004686476,"domain_scores_codex":[0.9987219,0.00006838989,0.0001988159,0.0005845612,0.00008556399,0.0003407784],"domain_scores_gemma":[0.9993328,0.00003513013,0.0001282575,0.0003185509,0.0001115432,0.0000736464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003194214,0.0001469841,0.00110916,0.00002834296,0.00009388987,0.00001147178,0.00008221492,0.005007685,0.9923501,0.0001035133,0.0002505456,0.0004966977],"study_design_scores_gemma":[0.0008078442,0.0005121939,0.0001703838,0.00003692302,0.00003835384,0.00001625825,0.0000488696,0.00001997299,0.95143,0.0003771821,0.04624427,0.0002978047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860986,0.006392196,0.002319935,0.0001242959,0.000384739,0.0001965505,0.00002273237,0.00006849928,0.004392392],"genre_scores_gemma":[0.9952443,0.00009623437,0.0028898,0.0006297475,0.000438882,0.00002498998,0.0004369435,0.00003882106,0.0002003164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04599373,"threshold_uncertainty_score":0.8408177,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1966857167","doi":"10.5402/2012/381428","title":"The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer Metastasis","year":2012,"lang":"en","type":"review","venue":"ISRN Molecular Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":337,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Royal Victoria Hospital; Royal Victoria Regional Health Centre","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Biology; Cancer research; Transforming growth factor; Metastasis; Cell growth; Signal transduction; Cancer; Cancer cell; Transforming growth factor beta; Tumor progression; Cell biology; Immunology; Genetics","authors":[{"name":"Jean-Charles Neel","is_ca":true},{"name":"Laure Humbert","is_ca":true},{"name":"Jean‐Jacques Lebrun","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02502861803931816,"gpt":0.3757535393398466,"spread":0.3507249213005285,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002685896,0.0005164125,0.001121707,0.0001305094,0.0001023863,0.00001872896,0.0007936796,0.0004704799,0.00009032353],"category_scores_gemma":[0.0001082252,0.0003693874,0.0004562694,0.0002031617,0.0001935566,0.000002552566,0.0005696645,0.0002735536,0.00001323297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006729639,"about_ca_system_score_gemma":0.0004274559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001300157,"about_ca_topic_score_gemma":0.001272272,"domain_scores_codex":[0.9970419,0.0006639659,0.000759065,0.0007500495,0.0001560301,0.000628935],"domain_scores_gemma":[0.9982902,0.00007598648,0.000454846,0.0009130762,0.00008975981,0.0001761327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007204415,0.0001481866,0.0006722706,0.0006526184,0.0008175577,0.00001390024,0.00004287877,0.00002959886,0.4357274,0.0001342204,0.0004170252,0.5612723],"study_design_scores_gemma":[0.000202684,0.00009644836,0.0000588717,0.0009263357,0.0005686405,0.000003931987,0.00001808278,5.124442e-7,0.09675466,0.00008869155,0.900873,0.0004081266],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02811696,0.9695753,0.00006040617,0.00002600718,0.0003530392,0.0006483967,0.001156399,0.00001176106,0.00005176481],"genre_scores_gemma":[0.0356298,0.9608019,0.0002466512,0.0001618643,0.0005342198,0.001033997,0.00139454,0.0001244406,0.00007259399],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.900456,"threshold_uncertainty_score":0.9998758,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2162291763","doi":"10.1038/35078562","title":"TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation","year":2001,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":310,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Ubiquitin ligase; Ubiquitin; Cell biology; SMAD; Smad2 Protein; Repressor; Transforming growth factor; Proteasome; Signal transduction; Ubiquitin-Protein Ligases; Transcription factor; Chemistry; WW domain; Biology; Biochemistry; Gene","authors":[{"name":"Shirin Bonni","is_ca":true},{"name":"Hongrui Wang","is_ca":true},{"name":"Carrie G. Causing","is_ca":true},{"name":"Peter A. Kavsak","is_ca":true},{"name":"Shannon L. Stroschein","is_ca":false},{"name":"Kunxin Luo","is_ca":false},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02354200213501783,"gpt":0.2953489773695344,"spread":0.2718069752345165,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001969312,0.0002202845,0.0002574418,0.00008264105,0.0000816566,0.0000116805,0.0003171731,0.0007892756,0.00005059874],"category_scores_gemma":[0.0001995439,0.0001996948,0.0001477755,0.00009333043,0.0001113222,0.000004684252,0.00009033911,0.0001907317,0.000006461618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001505982,"about_ca_system_score_gemma":0.0001021921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001277485,"about_ca_topic_score_gemma":0.00002703802,"domain_scores_codex":[0.9987478,0.0001016133,0.0002661555,0.0004602726,0.00008769552,0.0003364701],"domain_scores_gemma":[0.9990895,0.00007246574,0.0002367203,0.0003268799,0.0001846815,0.00008974075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002713628,0.0001535584,0.003577081,0.00005207344,0.00004376455,0.000002175813,0.00002027021,0.00002299051,0.9890358,0.00008516493,0.004875221,0.001860502],"study_design_scores_gemma":[0.000647545,0.0003844347,0.002247706,0.00001118119,0.00003144184,0.000005385325,0.00003844502,0.00004439172,0.8550633,0.00009993438,0.1412289,0.0001973303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920433,0.004704397,0.00122735,0.0001752271,0.0002970807,0.0003555765,0.0001512294,0.00002598934,0.001019919],"genre_scores_gemma":[0.9936723,0.0001294116,0.002352725,0.0004302891,0.000318408,0.00004712941,0.002589384,0.00002852538,0.0004318398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1363537,"threshold_uncertainty_score":0.8143317,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2074883939","doi":"10.1073/pnas.061358098","title":"Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type β signaling","year":2001,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":296,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"","keywords":"MEN1; Carcinogenesis; Cancer research; Biology; Multiple endocrine neoplasia; Tumor suppressor gene; Gene product; Suppressor; Transforming growth factor; Gene; Cell biology; Genetics; Gene expression","authors":[{"name":"Hiroshi Kaji","is_ca":true},{"name":"Lucie Canaff","is_ca":true},{"name":"Jean‐Jacques Lebrun","is_ca":true},{"name":"David Goltzman","is_ca":true},{"name":"Geoffrey N. Hendy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03380248144388581,"gpt":0.3012506254440875,"spread":0.2674481440002017,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004327446,0.00008679199,0.0001108167,0.00009331755,0.0001139083,0.00001185614,0.0004160875,0.00007805861,0.00001153533],"category_scores_gemma":[0.0009450328,0.00006506069,0.00006722815,0.0003832325,0.0002371891,0.00004247974,0.00006055134,0.00008738585,1.716801e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001500091,"about_ca_system_score_gemma":0.00005453663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005828819,"about_ca_topic_score_gemma":6.30255e-8,"domain_scores_codex":[0.99882,0.000006201017,0.0003120396,0.0001933442,0.0005487164,0.0001197216],"domain_scores_gemma":[0.9990081,0.00004018491,0.0004404123,0.000008333509,0.0004775721,0.00002535376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006498194,0.00004012838,0.00435408,0.00005645325,0.00001993735,3.674159e-9,0.0001382911,0.00008319512,0.994386,0.0005602556,0.00002511277,0.0002715819],"study_design_scores_gemma":[0.0001272421,0.00008798279,0.002213655,0.0001803849,0.000008764544,0.000003560102,0.0001632776,0.0001383741,0.9953359,0.001541768,0.0001279532,0.00007115927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998365,0.0001262887,0.00001740358,0.0001889789,0.00001292917,0.0001731501,0.000005568328,0.000005162939,0.001105549],"genre_scores_gemma":[0.9986523,0.00000972449,0.00113728,0.00003895015,0.00007883776,0.000007491987,5.662401e-7,0.000005297701,0.00006956518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002140425,"threshold_uncertainty_score":0.2653098,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2036472425","doi":"10.1126/science.287.5450.92","title":"Structural Basis of Smad2 Recognition by the Smad Anchor for Receptor Activation","year":2000,"lang":"en","type":"article","venue":"Science","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":295,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Mount Sinai Hospital","funders":"National Cancer Institute","keywords":"SMAD; Receptor; Coiled coil; Phosphorylation; Serine; Signal transduction; Biophysics; Cell biology; Chemistry; Biology; Biochemistry","authors":[{"name":"Geng Wu","is_ca":false},{"name":"Ye‐Guang Chen","is_ca":false},{"name":"Barish Ozdamar","is_ca":true},{"name":"Cassie A. Gyuricza","is_ca":false},{"name":"P. Andrew Chong","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Joan Massagué","is_ca":false},{"name":"Yigong Shi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01601040951627019,"gpt":0.2642535300747919,"spread":0.2482431205585217,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000203251,0.00004930187,0.0000382503,0.00001415633,0.000141243,0.00001817773,0.0002037552,0.00002863145,0.0001177517],"category_scores_gemma":[0.0002073074,0.00003613205,0.00002897833,0.00012213,0.0002346246,0.000008696989,0.00001549044,0.00001945496,0.000004150651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000886945,"about_ca_system_score_gemma":0.00007380711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006042351,"about_ca_topic_score_gemma":0.000001412518,"domain_scores_codex":[0.9994794,0.00001861661,0.00008739404,0.0001823618,0.0001151259,0.0001171501],"domain_scores_gemma":[0.999657,0.00002028906,0.00004662679,0.0001536513,0.00009271896,0.00002970363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005823873,0.000008236119,0.0001556342,0.000004505249,0.000002561469,3.961704e-9,0.00002736355,0.00001715639,0.9290989,0.000001718749,0.001320059,0.06930562],"study_design_scores_gemma":[0.0001204657,0.00007162065,0.002524359,0.000007733282,0.000003865115,3.371152e-7,0.00002747115,0.00006357494,0.9888055,0.00009981261,0.00821991,0.00005531622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991567,0.00009449993,0.0001999615,0.0001086971,0.00006512846,0.0001390817,0.00006108793,0.000005121473,0.0001697053],"genre_scores_gemma":[0.998515,0.000008392513,0.0009096835,0.0001085912,0.00007695953,0.0000203148,0.00008269849,0.000004264736,0.0002741486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06925031,"threshold_uncertainty_score":0.1473422,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101417810","doi":"10.1681/asn.2004060436","title":"Transient Overexpression of TGF-β1 Induces Epithelial Mesenchymal Transition in the Rodent Peritoneum","year":2004,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":292,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"American Society of Nephrology","keywords":"Peritoneum; Epithelial–mesenchymal transition; Rodent; Mesenchymal stem cell; Transforming growth factor; Transient (computer programming); Rodent model; Cell biology; Transition (genetics); Pathology; Chemistry; Cancer research; Biology; Medicine; Internal medicine; Gene; Computer science; Biochemistry","authors":[{"name":"Peter J. Margetts","is_ca":true},{"name":"Philippe Bonniaud","is_ca":false},{"name":"Limin Liu","is_ca":false},{"name":"Catherine M. Hoff","is_ca":false},{"name":"Clifford J. Holmes","is_ca":false},{"name":"Judith A. West‐Mays","is_ca":false},{"name":"Margaret M. Kelly","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009886124390482575,"gpt":0.2597634745509204,"spread":0.2498773501604378,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003541452,0.0001144982,0.0002835112,0.00002716984,0.00005250336,0.000004581339,0.0004608865,0.00008236678,0.000005422719],"category_scores_gemma":[0.00002599528,0.00006986113,0.0004688775,0.0001356546,0.0006328129,0.000007125359,0.0000395779,0.0002082032,1.778722e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002277745,"about_ca_system_score_gemma":0.0001859966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009160608,"about_ca_topic_score_gemma":0.00001025135,"domain_scores_codex":[0.9987507,0.0002339071,0.000437222,0.0001240804,0.0002898364,0.0001642652],"domain_scores_gemma":[0.9989433,0.00003775186,0.0006592574,0.000226125,0.00009781102,0.00003575356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003870466,0.0002751971,0.0002166906,0.00001733121,0.00008847596,0.000001612162,0.003147853,0.004352702,0.9904552,0.00000493964,0.0006195604,0.0004334057],"study_design_scores_gemma":[0.001959001,0.002092392,0.1183259,0.0001340581,0.0001190345,0.0002051611,0.006319281,0.00003518651,0.8667748,0.0002684998,0.003599602,0.0001671546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955559,0.0003953454,0.0004189772,0.003442035,0.00006259479,0.00009750937,0.00001525517,0.000001303882,0.0000110609],"genre_scores_gemma":[0.9966613,0.0001736352,0.0009297302,0.001993593,0.0002244764,0.000002717654,0.000002633365,0.000009413304,0.000002521687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1236804,"threshold_uncertainty_score":0.2848854,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2153203105","doi":"10.1016/j.molcel.2007.11.039","title":"Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding","year":2008,"lang":"en","type":"article","venue":"Molecular Cell","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":286,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Cell biology; Receptor; Signal transduction; SMAD; Bone morphogenetic protein; Transforming growth factor; BMPR2; Avidity; Extracellular; Ligand (biochemistry); Biochemistry; Genetics","authors":[{"name":"Jay C. Groppe","is_ca":false},{"name":"Cynthia S. Hinck","is_ca":false},{"name":"Payman Samavarchi‐Tehrani","is_ca":true},{"name":"Chloé Zubieta","is_ca":false},{"name":"Jonathan P. Schuermann","is_ca":false},{"name":"Alexander B. Taylor","is_ca":false},{"name":"Patricia M. Schwarz","is_ca":false},{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Andrew P. Hinck","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01230160891213645,"gpt":0.2355035759219078,"spread":0.2232019670097714,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001255223,0.0002565295,0.000337044,0.00005849186,0.0001068342,0.00001354053,0.000211471,0.0001168284,0.00003936261],"category_scores_gemma":[0.00007236744,0.0002524942,0.0001008312,0.000131902,0.0002243319,0.000007102768,0.0001283942,0.00007984649,0.000007144702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001038894,"about_ca_system_score_gemma":0.00008900345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004811201,"about_ca_topic_score_gemma":0.000002920533,"domain_scores_codex":[0.9985504,0.0001363814,0.0003783643,0.0004301602,0.0002444806,0.0002602483],"domain_scores_gemma":[0.9991895,0.00004493436,0.0001861372,0.0002820637,0.0001719441,0.0001254405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000091358,0.0001563593,0.0009549557,0.00006548355,0.0000858219,0.000007795788,0.0001486379,0.0004147533,0.9973692,0.00002821086,0.0006518348,0.00002553068],"study_design_scores_gemma":[0.0008356307,0.0003016771,0.00007364171,0.00004080726,0.00004401975,0.000003091797,0.0001062547,0.0005815862,0.9974204,0.00001494362,0.0003094298,0.00026857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980363,0.002329674,0.01638105,0.00001349727,0.00003176934,0.0002019747,0.0004374497,0.00001424246,0.0002274139],"genre_scores_gemma":[0.9961994,0.00009290963,0.002773591,0.00008656664,0.00001668254,0.00001492053,0.0006374524,0.00004468517,0.0001338182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01583644,"threshold_uncertainty_score":0.9999927,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2050331605","doi":"10.1074/jbc.m107081200","title":"Transforming Growth Factor-β Repression of Matrix Metalloproteinase-1 in Dermal Fibroblasts Involves Smad3","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":283,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"University of California, San Francisco; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Ludwig Institute for Cancer Research; Hospital for Sick Children; Dartmouth College; Johns Hopkins University","keywords":"Psychological repression; Transforming growth factor; Matrix metalloproteinase; Cell biology; Matrix (chemical analysis); Growth factor; Chemistry; Cancer research; Biology; Biochemistry; Gene expression; Gene","authors":[{"name":"Weihua Yuan","is_ca":false},{"name":"John Varga","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02057410844919435,"gpt":0.2717128039867407,"spread":0.2511386955375464,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002187058,0.0001811965,0.0003322772,0.00004013251,0.00003028329,0.00001088651,0.0003222902,0.0003072451,0.0001102327],"category_scores_gemma":[0.0004076271,0.0001317078,0.0002495109,0.0001086514,0.0001192312,0.00001101351,0.00007413021,0.000216662,7.618628e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000208576,"about_ca_system_score_gemma":0.00009068589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004135577,"about_ca_topic_score_gemma":0.000001069436,"domain_scores_codex":[0.99864,0.00005786962,0.0006543436,0.0002259323,0.0001880611,0.0002338094],"domain_scores_gemma":[0.9991396,0.00004054969,0.0003785386,0.0001698551,0.0001388011,0.0001326636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004938229,0.0001808901,0.02551014,0.00008701487,0.0000436004,0.0000596818,0.0000243035,0.00009560856,0.9729259,0.000001513128,0.00003311707,0.0005444164],"study_design_scores_gemma":[0.000668924,0.0002315195,0.007580452,0.000154423,0.00001392601,0.0001441777,0.00007156244,0.000008130304,0.9900506,0.00008411116,0.0008363359,0.0001558669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964792,0.002776639,0.0003943385,0.00003959938,0.0000317248,0.00007374655,0.00001135904,0.000006100213,0.0001872613],"genre_scores_gemma":[0.9985321,0.0002965241,0.0008518178,0.00002252503,0.000193673,0.000003604958,0.00002137016,0.00001140171,0.00006703558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01792969,"threshold_uncertainty_score":0.5370889,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1991714991","doi":"10.1016/j.molcel.2005.06.028","title":"Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain","year":2005,"lang":"en","type":"article","venue":"Molecular Cell","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":279,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Ubiquitin ligase; Ubiquitin; Biology; Ubiquitin-Protein Ligases; DNA ligase; Cell biology; Ubiquitin-conjugating enzyme; NEDD4; Signal transduction; HEK 293 cells; Receptor; Enzyme; Biochemistry; Gene","authors":[{"name":"Abiodun A. Ogunjimi","is_ca":true},{"name":"Douglas J. Briant","is_ca":true},{"name":"Nadia Pece-Barbara","is_ca":true},{"name":"Christine Le Roy","is_ca":true},{"name":"Gianni M. Di Guglielmo","is_ca":true},{"name":"Peter A. Kavsak","is_ca":true},{"name":"Richele K. Rasmussen","is_ca":true},{"name":"Bruce T. Seet","is_ca":true},{"name":"Frank Sicheri","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004501579249315568,"gpt":0.2205846257243096,"spread":0.216083046474994,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002615857,0.0001392705,0.00009856445,0.00001994308,0.0001059694,0.00002468612,0.0003144169,0.0000761503,0.00001963279],"category_scores_gemma":[0.00005469485,0.00009917006,0.0001063828,0.0001039014,0.00005674197,0.00000335703,0.0001326425,0.00007962864,0.00001693388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001773417,"about_ca_system_score_gemma":0.00004455903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000200438,"about_ca_topic_score_gemma":0.00002037201,"domain_scores_codex":[0.9990233,0.0001418456,0.0001574948,0.0002720119,0.0001924144,0.0002128992],"domain_scores_gemma":[0.9991722,0.00001951283,0.00009184673,0.0005977587,0.00004940157,0.00006933328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000539437,0.00007371764,0.0001213026,0.00001144797,0.00001871687,0.000001147096,0.00008496835,0.002388487,0.9880925,0.00001616711,0.005458405,0.003679126],"study_design_scores_gemma":[0.0001854856,0.00006332021,0.0004612181,0.000009503317,0.000017584,0.000001367983,0.00002603157,0.00007270023,0.9037485,0.00002234699,0.09527983,0.0001121447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861352,0.001320988,0.01020737,0.0008953987,0.00004641519,0.0002731871,0.00002018366,0.0000122895,0.001089008],"genre_scores_gemma":[0.9980093,0.000009566327,0.0007172957,0.0005471976,0.0001919055,0.00003243993,0.00003346119,0.00002558493,0.0004332423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08982143,"threshold_uncertainty_score":0.4044038,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2084294723","doi":"10.1016/s1359-6101(99)00024-6","title":"The Smad pathway","year":2000,"lang":"en","type":"review","venue":"Cytokine & Growth Factor Reviews","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":257,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"SMAD; Cell biology; Signal transduction; Phosphorylation; Intracellular; Smad2 Protein; Receptor; Biology; Proteasome; Serine; R-SMAD; Cytoplasm; Chemistry; Biochemistry; Growth factor; TGF alpha","authors":[{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Liliana Attisano","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04767777068088849,"gpt":0.3213252303561003,"spread":0.2736474596752118,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005246169,0.0009170204,0.001903236,0.00006653356,0.0002996626,0.0001314929,0.001388647,0.0004863498,0.0002208202],"category_scores_gemma":[0.0007060432,0.0005366326,0.001612822,0.0002534479,0.0001679311,0.000004681654,0.0002519605,0.000422478,0.000950923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005451631,"about_ca_system_score_gemma":0.0004527336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003780717,"about_ca_topic_score_gemma":0.000007116845,"domain_scores_codex":[0.9960252,0.0008500121,0.001333754,0.0009088086,0.0002668973,0.0006153223],"domain_scores_gemma":[0.9971885,0.0001368043,0.0007048206,0.001640808,0.00007943372,0.0002496224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001151424,0.00004484206,0.000005359655,0.004984032,0.000123439,0.000006309202,0.000005477924,3.860232e-8,0.00004775186,0.00001935744,0.01268308,0.9820688],"study_design_scores_gemma":[0.0001330213,0.00007812804,0.000004928751,0.00392783,0.0003061999,0.00002768551,8.508511e-7,6.554863e-8,0.0002778995,0.000009057723,0.9946166,0.0006177879],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002236452,0.996415,0.00002177872,0.00001260421,0.0003790641,0.001590664,0.0003211196,0.0000439333,0.001193482],"genre_scores_gemma":[0.00001443974,0.9942794,0.00006177677,0.0001499927,0.001288581,0.0005739947,0.001099286,0.0001574103,0.002375079],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9819335,"threshold_uncertainty_score":0.999827,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2058733924","doi":"10.1038/sj.onc.1207412","title":"Regulation of the TGFβ signalling pathway by ubiquitin-mediated degradation","year":2004,"lang":"en","type":"review","venue":"Oncogene","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":253,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"SMAD; Ubiquitin; Biology; Cell biology; Smad2 Protein; Signal transduction; Ubiquitin ligase; R-SMAD; Transforming growth factor; Phosphorylation; Ubiquitin-Protein Ligases; Receptor; Biochemistry; TGF alpha; Growth factor","authors":[{"name":"Luisa Izzi","is_ca":true},{"name":"Liliana Attisano","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02053849545046072,"gpt":0.2764596920785505,"spread":0.2559211966280898,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002150249,0.0002839674,0.0004728294,0.00003939771,0.00009029992,0.0000156463,0.0003737383,0.0003852719,0.0000404122],"category_scores_gemma":[0.0001989825,0.000211826,0.0003730516,0.0001610541,0.00007447004,0.000002499726,0.0001048342,0.0001352071,0.00001677058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006694777,"about_ca_system_score_gemma":0.0007402194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008228848,"about_ca_topic_score_gemma":0.000004706982,"domain_scores_codex":[0.9984524,0.0002112251,0.0005301491,0.0003767213,0.0002429437,0.000186531],"domain_scores_gemma":[0.9987133,0.0000475888,0.0006010143,0.0004730768,0.0001033885,0.0000616152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001897445,0.0001861852,0.000008750373,0.006212284,0.0003031944,0.000001438042,0.00001832926,0.0001662571,0.4953968,0.00002973766,0.001336949,0.4963211],"study_design_scores_gemma":[0.000170377,0.00005056919,0.000002811264,0.00313093,0.0002408301,0.000005487414,0.000003421085,0.000002911592,0.1808955,0.00001821698,0.8152389,0.0002400276],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001461316,0.9968925,0.0005815547,0.000006715932,0.0001551947,0.0004446032,0.0002911253,0.0000156603,0.0001513185],"genre_scores_gemma":[0.007306913,0.9851634,0.0003570858,0.00003136006,0.0003110812,0.00007200016,0.005799209,0.00008677334,0.0008722119],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.813902,"threshold_uncertainty_score":0.8638012,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2126527070","doi":"10.1074/jbc.m909580199","title":"Placental Transforming Growth Factor-β Is a Downstream Mediator of the Growth Arrest and Apoptotic Response of Tumor Cells to DNA Damage and p53 Overexpression","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":253,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; McMaster University; University of Toronto; Ontario Institute for Cancer Research","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Biology; Carcinogenesis; Cancer research; Transforming growth factor; Cell cycle; Apoptosis; Cell growth; Cell cycle checkpoint; Tumor suppressor gene; Cell biology; Molecular biology; Cancer; Genetics","authors":[{"name":"Pei-Xiang Li","is_ca":true},{"name":"J. Tze‐Fei Wong","is_ca":true},{"name":"Ayeda Ayed","is_ca":true},{"name":"Duc Ngo","is_ca":true},{"name":"Anthony Brade","is_ca":true},{"name":"C.H. Arrowsmith","is_ca":true},{"name":"Richard C. Austin","is_ca":true},{"name":"Henry J. Klamut","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007284609627809201,"gpt":0.2223675427625997,"spread":0.2150829331347905,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001847727,0.0001627929,0.0002609016,0.00001823577,0.00004579525,0.00001227979,0.0002423514,0.0001570598,0.0001159368],"category_scores_gemma":[0.0002771954,0.00009923137,0.0001303833,0.00006280188,0.0002291184,0.000008220554,0.00007688134,0.0001405242,3.209629e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001242311,"about_ca_system_score_gemma":0.00007608281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002307126,"about_ca_topic_score_gemma":1.602991e-7,"domain_scores_codex":[0.9989766,0.00007755245,0.000409689,0.0001956859,0.0001786457,0.0001618021],"domain_scores_gemma":[0.9992527,0.00009725285,0.0002376394,0.0001443866,0.00008074816,0.0001872176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001910631,0.0001161961,0.006706145,0.0000950437,0.00003224408,0.000005332141,0.00009532109,0.00000271934,0.9907337,2.732303e-7,0.000145006,0.0001573396],"study_design_scores_gemma":[0.0006358616,0.0003126015,0.01784771,0.0001815981,0.00002188022,0.00004287225,0.000133315,0.000002218659,0.980479,0.00001471977,0.0002128401,0.0001154117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992049,0.0003939339,0.000005878615,0.00008689847,0.00002731925,0.00008547016,0.0001469003,0.000002591049,0.00004610917],"genre_scores_gemma":[0.9994763,0.0001224109,0.0001639586,0.0001011094,0.00009533123,0.000001581295,0.000004976725,0.000008539215,0.00002581417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01114156,"threshold_uncertainty_score":0.4046538,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2129115386","doi":"10.1158/0008-5472.can-04-3272","title":"Effect of Conditional Knockout of the Type II <i>TGF-β</i> Receptor Gene in Mammary Epithelia on Mammary Gland Development and Polyomavirus Middle T Antigen Induced Tumor Formation and Metastasis","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":249,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Immunovaccine (Canada); McGill University","funders":"National Cancer Institute; Vanderbilt-Ingram Cancer Center; Vanderbilt University","keywords":"Carcinogenesis; Biology; Mammary tumor; Mammary gland; Cancer research; Transforming growth factor; Conditional gene knockout; Metastasis; Mouse mammary tumor virus; Internal medicine; Cancer; Endocrinology; Pathology; Breast cancer; Immunology; Medicine; Phenotype; Gene; Virus","authors":[{"name":"Elizabeth Forrester","is_ca":false},{"name":"Anna Chytil","is_ca":false},{"name":"Brian Bierie","is_ca":false},{"name":"Mary Aakre","is_ca":false},{"name":"Agnieszka E. Gorska","is_ca":false},{"name":"Ali‐Reza Sharif‐Afshar","is_ca":false},{"name":"William J. Muller","is_ca":true},{"name":"Harold L. Moses","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03813312648499063,"gpt":0.3346635005458449,"spread":0.2965303740608543,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005242229,0.00009168786,0.0001307107,0.00008485516,0.00009231115,0.00001045554,0.0001621928,0.00005748308,0.00001493579],"category_scores_gemma":[0.00009713614,0.00006894957,0.00002354829,0.0001386465,0.00009307624,0.00001148918,0.0002138685,0.00009964025,0.00000123871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004009452,"about_ca_system_score_gemma":0.0002494823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003503924,"about_ca_topic_score_gemma":0.00004004757,"domain_scores_codex":[0.9989955,0.000212137,0.000190968,0.0001890363,0.000242628,0.000169772],"domain_scores_gemma":[0.999541,0.00005257784,0.00006565628,0.0001865592,0.0001000593,0.00005418212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004643604,0.00005230196,0.005582557,0.0001538743,0.00004484496,0.000001093437,0.0001517246,0.00001831108,0.972027,0.00001490847,0.0003274383,0.02116157],"study_design_scores_gemma":[0.0006417877,0.0003132577,0.02309493,0.00009291273,0.000005100585,0.00000320095,0.00001030966,0.00001493172,0.9723898,0.00001014352,0.003353666,0.00006998859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955391,0.0039099,0.00001449308,0.0001150085,0.00002922483,0.0002793866,0.00006323562,0.000002555237,0.0000471066],"genre_scores_gemma":[0.9991507,0.000275591,0.0002857003,0.00005129343,0.00004717592,0.00005464159,0.00006082883,0.000009516641,0.00006454613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02109159,"threshold_uncertainty_score":0.2811682,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2037838520","doi":"10.1016/s0002-9440(10)63970-3","title":"Evidence that Furin Is an Authentic Transforming Growth Factor-β1-Converting Enzyme","year":2001,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":242,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Montreal Clinical Research Institute; Université de Sherbrooke","funders":"Medical Research Council; Medical Research Council Canada; Arthritis Society","keywords":"Furin; Enzyme; Transforming growth factor; Chemistry; Biochemistry; Biology; Cell biology","authors":[{"name":"Claire M. Dubois","is_ca":true},{"name":"François Blanchette","is_ca":true},{"name":"Marie‐Hélène Laprise","is_ca":true},{"name":"Richard Leduc","is_ca":true},{"name":"Francine Grondin","is_ca":true},{"name":"Nabil G. Seidah","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03255472035222865,"gpt":0.2897995962665573,"spread":0.2572448759143287,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003065957,0.000185291,0.0003142948,0.0001111246,0.00008197884,0.00002142574,0.0004073447,0.00007839082,0.0000937232],"category_scores_gemma":[0.0002403509,0.0001669213,0.000181686,0.0001202131,0.0002510232,0.00002761423,0.00004297881,0.0001832491,0.000007867335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002261559,"about_ca_system_score_gemma":0.0001408482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001598728,"about_ca_topic_score_gemma":0.00000655631,"domain_scores_codex":[0.9985359,0.0002219283,0.0004190628,0.0002732654,0.000199932,0.0003499557],"domain_scores_gemma":[0.9987321,0.00005435706,0.0005972721,0.00025391,0.0001570606,0.0002052947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003312507,0.000129908,0.08407292,0.000018137,0.00008485482,0.0005803445,0.002112542,0.00001854515,0.8639942,0.000009270477,0.00006184001,0.04858623],"study_design_scores_gemma":[0.000993101,0.004628951,0.0471198,0.000238237,0.0001674852,0.005731104,0.002825573,0.00005826874,0.9351253,0.0001965793,0.002288763,0.000626836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987327,0.0017459,0.01044624,0.0002163787,0.0001514425,0.00005841365,0.000005701777,0.00001041869,0.00003845978],"genre_scores_gemma":[0.9974579,0.000424282,0.001015378,0.0007289813,0.0002931787,0.000002879978,0.000003759897,0.00002927409,0.00004432609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07113114,"threshold_uncertainty_score":0.6806855,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988824186","doi":"10.1152/ajprenal.00183.2002","title":"Central role for Rho in TGF-β<sub>1</sub>-induced α-smooth muscle actin expression during epithelial-mesenchymal transition","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Renal Physiology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":241,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Canadian Institutes of Health Research; Toronto General Hospital; University Health Network","funders":"National Institute of General Medical Sciences","keywords":"Stress fiber; Cytoskeleton; Cell biology; Epithelial–mesenchymal transition; Actin; RAC1; Rho-associated protein kinase; Biology; Transforming growth factor; Myosin; Signal transduction; Myosin light-chain kinase; Focal adhesion; Chemistry; Downregulation and upregulation; Cell; Biochemistry","authors":[{"name":"András Masszi","is_ca":true},{"name":"Caterina Di Ciano","is_ca":true},{"name":"Gábor Sirokmány","is_ca":true},{"name":"William T. Arthur","is_ca":false},{"name":"Ori D. Rotstein","is_ca":true},{"name":"Jiaxu Wang","is_ca":true},{"name":"Christopher A. McCulloch","is_ca":true},{"name":"László Rosivall","is_ca":false},{"name":"István Mucsi","is_ca":false},{"name":"András Kapùs","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005407745264797044,"gpt":0.2272117787373563,"spread":0.2218040334725592,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002376521,0.0003693204,0.0006933329,0.0001843311,0.0001437064,0.00001179995,0.0003585454,0.0002012176,0.00002044192],"category_scores_gemma":[0.0002194065,0.0003353173,0.0004079302,0.0001965893,0.0003318248,0.0000286135,0.00005434422,0.0003579322,0.000004207812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006434299,"about_ca_system_score_gemma":0.0002750576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001468069,"about_ca_topic_score_gemma":0.00001061076,"domain_scores_codex":[0.9972365,0.0005640886,0.0007073861,0.0005597744,0.0001649103,0.0007673255],"domain_scores_gemma":[0.9983912,0.0001130188,0.0007369349,0.0003461846,0.0001821302,0.0002305499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001934919,0.0003665877,0.00007966346,0.00003305279,0.00008637113,0.000005273977,0.0002236594,0.004151227,0.9903778,0.000009439209,0.00006868929,0.002663309],"study_design_scores_gemma":[0.001908901,0.001622835,0.07551581,0.0000758107,0.00003795031,0.0000271402,0.000457277,0.0000401321,0.9191054,0.0004551997,0.0004209138,0.0003325981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988188,0.000221768,0.000317491,0.00005365671,0.0002848322,0.000239038,0.00003489882,0.00001349731,0.00001597498],"genre_scores_gemma":[0.9980867,0.0000762669,0.0007381444,0.0002099069,0.0007285162,0.0000382454,0.0000640638,0.00005430956,0.000003835774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07543615,"threshold_uncertainty_score":0.9999099,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2164672043","doi":"10.1158/1078-0432.ccr-11-0544","title":"TGFβ1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells<i>In Vitro</i>and Promotes Tumor Control by Radiation<i>In Vivo</i>","year":2011,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":240,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; York University; U.S. Department of Defense","keywords":"Clonogenic assay; In vivo; Cancer research; Radiosensitivity; Growth inhibition; Cancer cell; Transforming growth factor; Radiation sensitivity; Cancer; Biology; In vitro; Chemistry; Medicine; Radiation therapy; Internal medicine; Endocrinology; Biochemistry; Irradiation","authors":[{"name":"Fanny Bouquet","is_ca":false},{"name":"Anupama Pal","is_ca":false},{"name":"Karsten A. Pilones","is_ca":false},{"name":"Sandra Demaria","is_ca":false},{"name":"Byron Hann","is_ca":false},{"name":"Rosemary J. Akhurst","is_ca":false},{"name":"Scott Lonning","is_ca":false},{"name":"J. Keith DeWyngaert","is_ca":false},{"name":"Silvia C. Formenti","is_ca":false},{"name":"Mary Helen Barcellos‐Hoff","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04347169386366349,"gpt":0.3680141626137282,"spread":0.3245424687500647,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001958153,0.0001358291,0.0002795162,0.00006714652,0.00007515105,0.0000191216,0.0001865275,0.0001303981,0.00007982442],"category_scores_gemma":[0.0004604869,0.0001073165,0.0000835875,0.0002050227,0.0007414287,0.00001098827,0.0001162296,0.0003680882,0.000001987606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004666477,"about_ca_system_score_gemma":0.0004500217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004905995,"about_ca_topic_score_gemma":0.0009538879,"domain_scores_codex":[0.9974378,0.0009505147,0.0004848111,0.0004583482,0.0002969447,0.0003715999],"domain_scores_gemma":[0.9987758,0.0004488504,0.0001255108,0.0003120697,0.000195328,0.0001424846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002243975,0.0006180755,0.08032631,0.00006663181,0.00004313455,0.00001278048,0.00007381738,0.00001231958,0.9093992,0.000006788401,0.003255488,0.003941527],"study_design_scores_gemma":[0.002147277,0.0001756418,0.09319974,0.00009469237,0.00001830427,0.000004349123,0.00004627334,0.0001314984,0.9029181,0.00006844191,0.001045623,0.0001500529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938859,0.00426452,0.00001297563,0.0004097245,0.00006400365,0.0005121164,0.000771896,0.000006125068,0.00007279338],"genre_scores_gemma":[0.9982121,0.0009149452,0.00002322832,0.0003152806,0.0002361865,0.0002122228,0.0000188668,0.00002193039,0.00004525798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01287343,"threshold_uncertainty_score":0.741643,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2150873412","doi":"10.1074/jbc.m410034200","title":"DRAGON, a Bone Morphogenetic Protein Co-receptor","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":237,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Bone morphogenetic protein; BMPR2; Noggin; Cell biology; Receptor; Biology; Bone morphogenetic protein 2; Transforming growth factor; Bone morphogenetic protein 10; Bone morphogenetic protein receptor; Bone morphogenetic protein 5; Bone morphogenetic protein 7; Chemistry; Biochemistry","authors":[{"name":"Tarek A. Samad","is_ca":false},{"name":"Anuradha Rebbapragada","is_ca":true},{"name":"Esther Bell","is_ca":false},{"name":"Ying E. Zhang","is_ca":false},{"name":"Yisrael Sidis","is_ca":false},{"name":"Sung‐Jin Jeong","is_ca":false},{"name":"Jason Campagna","is_ca":false},{"name":"Stephen Perusini","is_ca":true},{"name":"David Fabrizio","is_ca":false},{"name":"Alan L. Schneyer","is_ca":false},{"name":"Herbert Y. Lin","is_ca":false},{"name":"Ali H. Brivanlou","is_ca":false},{"name":"Liliana Attisano","is_ca":true},{"name":"Clifford J. Woolf","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01338566687119864,"gpt":0.2564324906395082,"spread":0.2430468237683096,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002972971,0.0001991616,0.0002593774,0.0000201179,0.00006790724,0.00002483731,0.0003508125,0.0002942116,0.0005912278],"category_scores_gemma":[0.0004256403,0.0001495296,0.000241574,0.00005835948,0.0001597816,0.000004182202,0.00007599182,0.0002549864,0.00005097967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003229275,"about_ca_system_score_gemma":0.0001381157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":3.832386e-7,"about_ca_topic_score_gemma":1.780205e-7,"domain_scores_codex":[0.9986976,0.00006201482,0.0005229296,0.0002450905,0.000200824,0.0002715222],"domain_scores_gemma":[0.9989905,0.0000206797,0.0003581471,0.0002342651,0.0001607599,0.0002356646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002402279,0.0002308332,0.001167706,0.00002225571,0.00005399307,0.00001524103,0.000008294261,0.00005691382,0.992361,7.301184e-7,0.004073288,0.0017695],"study_design_scores_gemma":[0.0005295851,0.0002326755,0.000517718,0.00003253654,0.00001239357,0.0001456121,0.00002506827,0.000003858803,0.8686749,0.00001149523,0.129636,0.0001780504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950454,0.003872709,0.0002046198,0.0001915862,0.0000401427,0.00008530344,0.0000299741,0.00001220476,0.0005180148],"genre_scores_gemma":[0.9943283,0.00007793251,0.003143852,0.0001888061,0.001508847,0.000009507136,0.00006545934,0.00001702567,0.0006602649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1255628,"threshold_uncertainty_score":0.6473529,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1917301047","doi":"10.1242/jcs.113.12.2221","title":"Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBFα/AML/PEBP2α) dependent activation of tissue-specific gene transcription","year":2000,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":232,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Biology; Transcription factor; Gene; Genetics; Transcription (linguistics); Cell biology; Nuclear matrix; Chromatin","authors":[{"name":"Amjad Javed","is_ca":false},{"name":"Bo Guo","is_ca":false},{"name":"Scott W. Hiebert","is_ca":false},{"name":"Je‐Yong Choi","is_ca":false},{"name":"Jack Green","is_ca":false},{"name":"Shan-Chuan Zhao","is_ca":false},{"name":"Mark A. Osborne","is_ca":false},{"name":"Stefano Stifani","is_ca":true},{"name":"Janet L. Stein","is_ca":false},{"name":"Jane B. Lian","is_ca":false},{"name":"André J. van Wijnen","is_ca":false},{"name":"Gary S. Stein","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00695805999695492,"gpt":0.227413032906287,"spread":0.2204549729093321,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005346927,0.00008820862,0.0001107663,0.0000449501,0.0001574922,0.00006412275,0.0003149286,0.00005047384,0.00004746742],"category_scores_gemma":[0.00002155612,0.00005867294,0.00004036941,0.0001424468,0.0002370958,0.00003385456,0.00002227086,0.00009895373,0.000001609713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003013757,"about_ca_system_score_gemma":0.0001012187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008896292,"about_ca_topic_score_gemma":0.000003155624,"domain_scores_codex":[0.998929,0.00005597562,0.0002292298,0.0001840741,0.0004468879,0.0001548009],"domain_scores_gemma":[0.9992539,0.00001085368,0.0003006757,0.0001861607,0.0001690689,0.00007939198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002099672,0.00007479956,0.0001457606,0.00001039961,0.000009920089,0.0000028161,0.0002645987,0.00055917,0.9958149,0.000006408306,0.00008776621,0.002813467],"study_design_scores_gemma":[0.0004142149,0.0003817889,0.006662219,0.00002917907,0.00002002725,0.00002979524,0.000102613,0.0000278037,0.9862946,0.00002105458,0.00593557,0.00008112918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978924,0.0007608593,0.0007219763,0.0001551283,0.00003722008,0.0001483376,0.00000342444,0.000003098725,0.0002775024],"genre_scores_gemma":[0.9981182,0.0001939818,0.001173889,0.00002926118,0.0001006178,0.000001899891,0.000001153148,0.000009862989,0.0003711735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009520321,"threshold_uncertainty_score":0.2392613,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2053009900","doi":"10.1038/modpathol.3800785","title":"High-level JAG1 mRNA and protein predict poor outcome in breast cancer","year":2007,"lang":"en","type":"article","venue":"Modern Pathology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":224,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children; Mount Sinai Hospital","funders":"National Cancer Institute; Society of University Surgeons","keywords":"JAG1; Medicine; Messenger RNA; Immunohistochemistry; Breast cancer; Pathology; Survival analysis; Internal medicine; Notch signaling pathway; Oncology; Receptor; Cancer; Gastroenterology; Biology; Gene","authors":[{"name":"Brendan C. Dickson","is_ca":true},{"name":"Anna Marie Mulligan","is_ca":true},{"name":"Hui Zhang","is_ca":true},{"name":"Gina Lockwood","is_ca":true},{"name":"Frances P. O’Malley","is_ca":true},{"name":"Sean E. Egan","is_ca":true},{"name":"Michael Reedijk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01611456480889427,"gpt":0.2698407135056422,"spread":0.2537261486967479,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002774361,0.0001704177,0.0001944538,0.00007432605,0.00004353481,0.00001025297,0.0001546886,0.0002310139,0.00002461034],"category_scores_gemma":[0.00004670399,0.0001629398,0.0000396031,0.00005102416,0.0001276679,0.000003856927,0.0001363687,0.0001210497,0.00000531671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002376281,"about_ca_system_score_gemma":0.00006235422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001033644,"about_ca_topic_score_gemma":0.0003193135,"domain_scores_codex":[0.9987471,0.00005825669,0.0002857153,0.0004466965,0.00009587166,0.0003663422],"domain_scores_gemma":[0.9995065,0.00001063994,0.00007519295,0.0002618851,0.00004437682,0.0001014609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002693771,0.0001170237,0.2512482,0.00003621742,0.00002039401,0.0001434074,0.00007917154,0.0001245437,0.7388532,0.00003755087,0.0001231614,0.00894777],"study_design_scores_gemma":[0.001611124,0.0001324094,0.8758335,0.00003492151,0.0000226832,0.0001796305,0.00002448392,0.0001775192,0.1203559,0.0004609139,0.0008124806,0.0003545475],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932806,0.001033134,0.004774111,0.000296646,0.0001091898,0.0002339265,0.0001750868,0.00002200515,0.00007523778],"genre_scores_gemma":[0.9974875,0.00001865867,0.001201034,0.0004412816,0.0001851762,0.00006434401,0.00005130149,0.00003007071,0.0005205633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6245852,"threshold_uncertainty_score":0.664449,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1984065470","doi":"10.1371/journal.pone.0012093","title":"ADAM10 Releases a Soluble Form of the GPNMB/Osteoactivin Extracellular Domain with Angiogenic Properties","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":224,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; McGill University Health Centre","funders":"Association Neurofibromatoses et Recklinghause; Canadian Breast Cancer Research Alliance; Canadian Institutes of Health Research; McGill University Health Centre; Celldex Therapeutics; McGill University","keywords":"Ectodomain; Cancer research; Breast cancer; Angiogenesis; Metastasis; Cell migration; Cancer; Cancer cell; Biology; Tumor microenvironment; Medicine; Internal medicine; Cell; Receptor","authors":[{"name":"April A. N. Rose","is_ca":true},{"name":"Matthew G. Annis","is_ca":true},{"name":"Zhifeng Dong","is_ca":true},{"name":"François Pépin","is_ca":false},{"name":"Michael Hallett","is_ca":true},{"name":"Morag Park","is_ca":true},{"name":"Peter M. Siegel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01675306367905038,"gpt":0.1819372128462171,"spread":0.1651841491671668,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008814378,0.0001419634,0.0001513033,0.00002286445,0.00009703841,0.00001750885,0.0002995477,0.0001031831,0.00004170283],"category_scores_gemma":[0.0001060944,0.00009200732,0.00009465156,0.00007804877,0.0001977103,0.000006400879,0.0001161345,0.0001153928,0.000005790658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006442366,"about_ca_system_score_gemma":0.0001621445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002372425,"about_ca_topic_score_gemma":0.0001835865,"domain_scores_codex":[0.9990866,0.00003528411,0.00016366,0.0002403626,0.0002586389,0.0002155004],"domain_scores_gemma":[0.9991025,0.00001179963,0.0001153069,0.0005958933,0.0001091836,0.00006535013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001994582,0.0007789946,0.007693429,0.00008137313,0.0002147435,0.000001457972,0.00009827012,0.000004366877,0.9907027,0.00002433057,0.0001087614,0.00009212123],"study_design_scores_gemma":[0.0003888684,0.0002413815,0.001534216,0.0001049779,0.0001170196,0.0000053174,0.00006772934,0.00001731949,0.9963579,0.00005463623,0.0009583227,0.0001522653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976177,0.001640961,0.00004070833,0.00009100558,0.00003663006,0.0003289539,0.00001476521,0.00001848482,0.0002108534],"genre_scores_gemma":[0.9965279,0.00001195239,0.001817708,0.00003773889,0.0001288155,0.0000609334,0.00001709781,0.00003317946,0.001364716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006159212,"threshold_uncertainty_score":0.375195,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1937225926","doi":"10.1101/gad.912901","title":"Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN","year":2001,"lang":"en","type":"article","venue":"Genes & Development","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":218,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"Tobacco-Related Disease Research Program; U.S. Department of Defense; National Cancer Institute; National Science Foundation; National Institutes of Health; American Cancer Society","keywords":"Ubiquitin; Cell biology; Biology; Ubiquitin ligase; Deubiquitinating enzyme; Regulator; Signal transduction; Transforming growth factor; Proteasome; Ubiquitin-conjugating enzyme; Biochemistry; Gene","authors":[{"name":"Shannon L. Stroschein","is_ca":false},{"name":"Shirin Bonni","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Kunxin Luo","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04437715544709919,"gpt":0.291446078508454,"spread":0.2470689230613548,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002217268,0.00008551265,0.00007306078,0.00002643493,0.00013454,0.00001503058,0.00009298189,0.00004261466,0.000007623414],"category_scores_gemma":[0.00005714411,0.00007066012,0.00002354407,0.00005188907,0.0000331264,0.000002859651,0.00005077284,0.00001561779,7.174211e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001197912,"about_ca_system_score_gemma":0.0000807001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000347035,"about_ca_topic_score_gemma":0.00003003141,"domain_scores_codex":[0.9993774,0.00002817814,0.0001970244,0.0001781163,0.0000923708,0.0001268625],"domain_scores_gemma":[0.9996306,0.00002096917,0.0001016179,0.0001162402,0.00009942173,0.00003116528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005076366,0.00004696779,0.005844937,0.00004987141,0.00004244981,3.905947e-7,0.0002471857,0.00003584115,0.6771293,0.00003677987,0.0002936782,0.3162219],"study_design_scores_gemma":[0.0003766655,0.00007101788,0.03775872,0.00002550617,0.00001495445,0.000006577347,0.0001011456,0.0001774488,0.8706258,0.00005694785,0.09066207,0.0001231683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899931,0.001028287,0.008434443,0.000108111,0.0000467207,0.0002958262,0.000006211247,0.000008851121,0.00007845232],"genre_scores_gemma":[0.986779,0.00008775304,0.01235311,0.00008831193,0.00006642724,0.00007036923,0.0003666096,0.00001186463,0.0001766002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3160987,"threshold_uncertainty_score":0.2881436,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2121765586","doi":"10.1158/0008-5472.can-05-1522","title":"Transforming Growth Factor-β Activation of Phosphatidylinositol 3-Kinase Is Independent of Smad2 and Smad3 and Regulates Fibroblast Responses via p21-Activated Kinase-2","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":213,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"National Institute of General Medical Sciences; Mayo Foundation for Medical Education and Research","keywords":"Phosphatidylinositol; Kinase; Cell biology; Fibroblast growth factor; Cancer research; Chemistry; Biology; Biochemistry; Receptor","authors":[{"name":"Mark C. Wilkes","is_ca":false},{"name":"Hugh Mitchell","is_ca":false},{"name":"Sumedha G. Penheiter","is_ca":false},{"name":"Jules J.E. Doré","is_ca":true},{"name":"Kaori Suzuki","is_ca":false},{"name":"Maryanne Edens","is_ca":false},{"name":"Deepak Sharma","is_ca":false},{"name":"Richard E. Pagano","is_ca":false},{"name":"Edward B. Leof","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03106387104976036,"gpt":0.3337636538396633,"spread":0.3026997827899029,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002304241,0.0001417312,0.0001803986,0.0001441154,0.0001064377,0.00002162919,0.000143257,0.0001482517,0.00005955597],"category_scores_gemma":[0.0001436701,0.0001368246,0.00004209673,0.0001764695,0.0002889092,0.00002232813,0.00009288608,0.0001392539,4.43314e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004220561,"about_ca_system_score_gemma":0.0002045028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002795413,"about_ca_topic_score_gemma":0.00002758684,"domain_scores_codex":[0.9986676,0.0001220781,0.0002574963,0.0003464675,0.0003403563,0.0002660142],"domain_scores_gemma":[0.9991336,0.0001018496,0.00009383645,0.0002203647,0.0003329423,0.0001174371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001042132,0.00008534927,0.005858056,0.000246887,0.00006428774,0.000001001324,0.0004533639,0.00002241653,0.9818525,0.00001029375,0.0001075369,0.01025616],"study_design_scores_gemma":[0.0006983675,0.0003402195,0.01777439,0.0002100256,0.000009424144,0.00000188537,0.0001200234,0.00003136955,0.9799234,0.0000375828,0.0007224116,0.0001309553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968649,0.002383882,0.0001183877,0.0001807643,0.00001308446,0.0003079856,0.00009316134,0.000007821794,0.00003005122],"genre_scores_gemma":[0.9990997,0.0004130386,0.000152637,0.0000205904,0.00007373327,0.00003946979,0.00002642027,0.00002452528,0.0001498272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01191633,"threshold_uncertainty_score":0.5579546,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3217209761","doi":"10.3389/fcell.2021.786728","title":"TGF-β Signaling and Resistance to Cancer Therapy","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":196,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"State Key Laboratory of Membrane Biology","keywords":"Cancer; Transforming growth factor; Carcinogenesis; Cancer research; Immunotherapy; Targeted therapy; Medicine; Drug resistance; Cancer cell; Transforming growth factor beta; Signal transduction; Clinical trial; Oncology; Biology; Internal medicine; Cell biology","authors":[{"name":"Maoduo Zhang","is_ca":false},{"name":"Ying Yi Zhang","is_ca":true},{"name":"Yongze Chen","is_ca":false},{"name":"Jia Wang","is_ca":false},{"name":"Qiang Wang","is_ca":false},{"name":"Hezhe Lu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0204164021815464,"gpt":0.291317286246124,"spread":0.2709008840645776,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001337064,0.0003520325,0.000783836,0.0001225603,0.00007852579,0.00002632903,0.0001814237,0.0003815843,0.00002298339],"category_scores_gemma":[0.00003024107,0.0003108599,0.00008111214,0.0001418524,0.0001128406,0.000002251734,0.0002189131,0.00013921,0.000002728275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005522115,"about_ca_system_score_gemma":0.0004135801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000871689,"about_ca_topic_score_gemma":0.00002822174,"domain_scores_codex":[0.998373,0.0001383627,0.0003736478,0.0007442248,0.00005592146,0.0003148993],"domain_scores_gemma":[0.9995649,0.00002804752,0.0001035402,0.0001471904,0.00002631163,0.0001299521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008889312,0.0000755912,0.003994704,0.002163587,0.0002686886,0.00002578887,0.0001777972,8.172467e-7,0.004325149,0.000008615778,0.02404851,0.9648219],"study_design_scores_gemma":[0.0002596187,0.00003814916,0.00002656599,0.001099566,0.00002869649,0.000006444529,0.00008664007,9.987526e-8,0.00335929,0.00002334774,0.9946563,0.0004153138],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004633227,0.9939649,0.0001955642,0.0000119419,0.0004146305,0.0003332531,0.00006961592,0.000008005121,0.0003688596],"genre_scores_gemma":[0.0002564728,0.9817331,0.01600794,0.0002303917,0.0001148472,0.0001759873,0.0003846497,0.00003577961,0.001060789],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9706078,"threshold_uncertainty_score":0.9999344,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2095911832","doi":"10.1158/1078-0432.ccr-09-1611","title":"Glycoprotein Nonmetastatic B Is an Independent Prognostic Indicator of Recurrence and a Novel Therapeutic Target in Breast Cancer","year":2010,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Institute for Research in Immunology and Cancer; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Celldex Therapeutics","keywords":"Breast cancer; Medicine; Cancer; Triple-negative breast cancer; Oncology; CA15-3; Tissue microarray; Internal medicine; Metastasis; Antibody-drug conjugate; Cancer research; Targeted therapy; Population; Clinical significance; Antibody; Immunology; Monoclonal antibody","authors":[{"name":"April A. N. Rose","is_ca":true},{"name":"Andrée‐Anne Grosset","is_ca":true},{"name":"Zhifeng Dong","is_ca":true},{"name":"Caterina Russo","is_ca":true},{"name":"Patricia MacDonald","is_ca":true},{"name":"Nicholas Bertos","is_ca":true},{"name":"Yves St‐Pierre","is_ca":true},{"name":"Ronit Simantov","is_ca":true},{"name":"Michael Hallett","is_ca":true},{"name":"Morag Park","is_ca":true},{"name":"Louis Gaboury","is_ca":true},{"name":"Peter M. Siegel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1077294702145665,"gpt":0.4723734196999974,"spread":0.3646439494854308,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001737677,0.0001434815,0.0002548624,0.0001112883,0.00006410123,0.00003135168,0.0004494877,0.0002247773,0.0003415052],"category_scores_gemma":[0.000430065,0.0001263037,0.00005902603,0.000228103,0.0007149435,0.00001007343,0.0002346844,0.000752416,0.000004954258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002005733,"about_ca_system_score_gemma":0.001023007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005551496,"about_ca_topic_score_gemma":0.0007763566,"domain_scores_codex":[0.9977279,0.0002624776,0.0004897105,0.0006370698,0.0004741502,0.0004086659],"domain_scores_gemma":[0.9987319,0.0001730491,0.0001284451,0.0004633128,0.000229169,0.0002741915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006682951,0.0008155489,0.7177712,0.0001354856,0.00006555083,0.000004483855,0.0001243964,0.000008395026,0.2590586,0.00003141503,0.0001359403,0.02118074],"study_design_scores_gemma":[0.001846417,0.0006071197,0.9294434,0.0001724847,0.00002602904,0.000007685277,0.00009218944,0.0002805467,0.06497048,0.0003764238,0.001897828,0.0002793572],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963605,0.002118183,0.00008821254,0.0004388324,0.0001320598,0.0005521369,0.000289398,0.000005471332,0.00001516153],"genre_scores_gemma":[0.9982592,0.0003750671,0.0004974006,0.0001844723,0.0002253898,0.0003722477,0.00002101104,0.00002659081,0.00003855603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2116723,"threshold_uncertainty_score":0.5150515,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2001321108","doi":"10.1073/pnas.97.9.4820","title":"Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor β signaling by targeting Smads to the ubiquitin–proteasome pathway","year":2000,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":193,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"SMAD; Ubiquitin; Smad2 Protein; Biology; ACVRL1; Signal transduction; R-SMAD; Phosphorylation; Cell biology; Transforming growth factor; TGF beta receptor 2; Ubiquitin ligase; Cancer research; Receptor; Genetics; TGF alpha; Growth factor; Endoglin; Gene","authors":[{"name":"Jing Xu","is_ca":true},{"name":"Liliana Attisano","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01714602914091193,"gpt":0.2662303891942374,"spread":0.2490843600533254,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001042268,0.0001037135,0.0001003769,0.00007480515,0.000225944,0.0000398909,0.0006844698,0.00005263948,0.00001024693],"category_scores_gemma":[0.0004994302,0.0000592063,0.00004471315,0.0004458373,0.0003327153,0.00004046827,0.00005181973,0.0001437939,3.358719e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001368353,"about_ca_system_score_gemma":0.00003802035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001925892,"about_ca_topic_score_gemma":6.162484e-7,"domain_scores_codex":[0.9987471,0.00002445694,0.0002894785,0.000246949,0.0005035229,0.0001884934],"domain_scores_gemma":[0.9996341,0.0001062009,0.000135477,0.00001177846,0.00008274945,0.00002964652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002192247,0.00003975146,0.005670595,0.00003251125,0.000005943647,1.706507e-8,0.001203087,0.000417941,0.9917859,0.0003445604,0.00008874419,0.000389014],"study_design_scores_gemma":[0.0001508281,0.00004523081,0.01340236,0.00006903784,0.000004379072,0.000003520738,0.0008929141,0.0001430929,0.9829605,0.001716668,0.0005239578,0.00008746974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968178,0.0002741622,0.000002399562,0.00216787,0.000005639258,0.0003252073,0.00004505722,0.000003522078,0.0003583558],"genre_scores_gemma":[0.9991873,0.000009658288,0.0002585299,0.0004059143,0.00005011255,0.00005131453,0.000001503761,0.000005537236,0.00003011064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00882537,"threshold_uncertainty_score":0.2414363,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2894166779","doi":"10.1016/j.cels.2018.08.010","title":"A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily","year":2018,"lang":"en","type":"article","venue":"Cell Systems","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; National Institute on Alcohol Abuse and Alcoholism; Novo Nordisk Fonden; National Cancer Institute; National Institute for Academic Anaesthesia; Merck; U.S. Department of Veterans Affairs","keywords":"Biology; Transforming growth factor; ACVRL1; SMAD; R-SMAD; Gene; Genetics; Signal transduction; Cancer research; Mutation; DNA methylation; Cancer; Smad2 Protein; Receptor; Gene expression; Cell biology; Endoglin; Growth factor; TGF alpha","authors":[{"name":"Sobia Zaidi","is_ca":false},{"name":"Rupa S. Kanchi","is_ca":false},{"name":"Shuyun Rao","is_ca":false},{"name":"Nancy R. Gough","is_ca":false},{"name":"André Schultz","is_ca":false},{"name":"Xubin Li","is_ca":false},{"name":"Philip L. Lorenzi","is_ca":false},{"name":"Ashton C. Berger","is_ca":false},{"name":"Gordon Robertson","is_ca":true},{"name":"Lawrence N. Kwong","is_ca":false},{"name":"Mike Datto","is_ca":false},{"name":"Jason Roszik","is_ca":false},{"name":"Shiyun Ling","is_ca":false},{"name":"Visweswaran Ravikumar","is_ca":false},{"name":"Ganiraju C. Manyam","is_ca":false},{"name":"Arvind Rao","is_ca":false},{"name":"Simon Shelley","is_ca":false},{"name":"Yuexin Liu","is_ca":false},{"name":"Zhenlin Ju","is_ca":false},{"name":"Donna E. Hansel","is_ca":false},{"name":"Guillermo de Velasco","is_ca":false},{"name":"Arjun Pennathur","is_ca":false},{"name":"Jesper B. Andersen","is_ca":false},{"name":"Colm J. O’Rourke","is_ca":false},{"name":"Kazufumi Ohshiro","is_ca":false},{"name":"Wilma Jogunoori","is_ca":false},{"name":"Bao‐Ngoc Nguyen","is_ca":false},{"name":"Shulin Li","is_ca":false},{"name":"Hatice U. Osmanbeyoglu","is_ca":false},{"name":"Jaffer A. Ajani","is_ca":false},{"name":"Sendurai A. Mani","is_ca":false},{"name":"Andres Houseman","is_ca":false},{"name":"Maciej Wiznerowicz","is_ca":false},{"name":"Jian Chen","is_ca":false},{"name":"Shoujun Gu","is_ca":false},{"name":"Wencai Ma","is_ca":false},{"name":"Jiexin Zhang","is_ca":false},{"name":"Pan Tong","is_ca":false},{"name":"Andrew D. Cherniack","is_ca":false},{"name":"Linda Resar","is_ca":false},{"name":"Rory Johnson","is_ca":false},{"name":"John A. Demchok","is_ca":false},{"name":"Ina Felau","is_ca":false},{"name":"Melpomeni Kasapi","is_ca":false},{"name":"Martin L. Ferguson","is_ca":false},{"name":"Carolyn M. Hutter","is_ca":false},{"name":"Heidi J. Sofia","is_ca":false},{"name":"Roy Tarnuzzer","is_ca":false},{"name":"Liming Yang","is_ca":false},{"name":"Jean C. Zenklusen","is_ca":false},{"name":"Jiashan Zhang","is_ca":false},{"name":"Sudha Chudamani","is_ca":false},{"name":"Jia Liu","is_ca":false},{"name":"Laxmi Lolla","is_ca":false},{"name":"Rashi Naresh","is_ca":false},{"name":"Todd Pihl","is_ca":false},{"name":"Qiang Sun","is_ca":false},{"name":"Yunhu Wan","is_ca":false},{"name":"Ye Wu","is_ca":false},{"name":"Juok Cho","is_ca":false},{"name":"Timothy Defreitas","is_ca":false},{"name":"Scott Frazer","is_ca":false},{"name":"Nils Gehlenborg","is_ca":false},{"name":"Gad Getz","is_ca":false},{"name":"David I. Heiman","is_ca":false},{"name":"Michael S. Lawrence","is_ca":false},{"name":"Pei Lin","is_ca":false},{"name":"Michael S. Noble","is_ca":false},{"name":"Gordon Saksena","is_ca":false},{"name":"Doug Voet","is_ca":false},{"name":"Hailei Zhang","is_ca":false},{"name":"Brady Bernard","is_ca":true},{"name":"Nyasha Chambwe","is_ca":false},{"name":"Varsha Dhankani","is_ca":false},{"name":"Theo Knijnenburg","is_ca":false},{"name":"Roger Kramer","is_ca":false},{"name":"Kalle Leinonen","is_ca":false},{"name":"Michael B. Miller","is_ca":false},{"name":"Sheila M. Reynolds","is_ca":false},{"name":"Ilya Shmulevich","is_ca":false},{"name":"Vésteinn Thórsson","is_ca":false},{"name":"Wei Zhang","is_ca":false},{"name":"Rehan Akbani","is_ca":false},{"name":"Bradley M. Broom","is_ca":false},{"name":"Apurva M. Hegde","is_ca":false},{"name":"Jun Li","is_ca":false},{"name":"Han Liang","is_ca":false},{"name":"Wenbin Liu","is_ca":false},{"name":"Yiling Lu","is_ca":false},{"name":"Gordon B. Mills","is_ca":false},{"name":"Kwok-Shing Ng","is_ca":false},{"name":"Michaël Ryan","is_ca":false},{"name":"Jing Wang","is_ca":false},{"name":"John N. Weinstein","is_ca":false},{"name":"Adam Abeshouse","is_ca":false},{"name":"Joshua Armenia","is_ca":false},{"name":"Debyani Chakravarty","is_ca":false},{"name":"Walid K. Chatila","is_ca":false},{"name":"Ino de Bruijn","is_ca":false},{"name":"Jianjiong Gao","is_ca":false},{"name":"Benjamin Groß","is_ca":false},{"name":"Zachary Heins","is_ca":false},{"name":"Ritika Kundra","is_ca":false},{"name":"Konnor La","is_ca":false},{"name":"Marc Ladanyi","is_ca":false},{"name":"Augustin Luna","is_ca":false},{"name":"Moriah G. Nissan","is_ca":false},{"name":"Angelica Ochoa","is_ca":false},{"name":"Sarah Phillips","is_ca":false},{"name":"Ed Reznik","is_ca":false},{"name":"Francisco Sánchez-Vega","is_ca":false},{"name":"Chris Sander","is_ca":false},{"name":"Nikolaus Schultz","is_ca":false},{"name":"Robert P. Sheridan","is_ca":false},{"name":"S. Onur Sumer","is_ca":false},{"name":"Yichao Sun","is_ca":false},{"name":"Barry S. Taylor","is_ca":true},{"name":"Jioajiao Wang","is_ca":false},{"name":"Hongxin Zhang","is_ca":false},{"name":"Pavana Anur","is_ca":false},{"name":"Myron Peto","is_ca":false},{"name":"Paul T. Spellman","is_ca":false},{"name":"Christopher C. Benz","is_ca":false},{"name":"Joshua M. Stuart","is_ca":false},{"name":"Christopher K. Wong","is_ca":false},{"name":"Christina Yau","is_ca":false},{"name":"D. Neil Hayes","is_ca":false},{"name":"Joel S. Parker","is_ca":false},{"name":"Matthew D. Wilkerson","is_ca":false},{"name":"Adrian Ally","is_ca":false},{"name":"Miruna Balasundaram","is_ca":false},{"name":"Reanne Bowlby","is_ca":false},{"name":"Denise Brooks","is_ca":false},{"name":"Rebecca Carlsen","is_ca":false},{"name":"Eric Chuah","is_ca":false},{"name":"Noreen Dhalla","is_ca":false},{"name":"Robert A. Holt","is_ca":false},{"name":"Steven J.M. Jones","is_ca":false},{"name":"Darlene Lee","is_ca":true},{"name":"Yussanne Ma","is_ca":false},{"name":"Marco A. Marra","is_ca":false},{"name":"Michael Mayo","is_ca":false},{"name":"Richard A. Moore","is_ca":false},{"name":"Andrew J. Mungall","is_ca":false},{"name":"Karen Mungall","is_ca":false},{"name":"A. Gordon Robertson","is_ca":false},{"name":"Sara Sadeghi","is_ca":false},{"name":"Jacqueline E. Schein","is_ca":false},{"name":"Payal Sipahimalani","is_ca":true},{"name":"Angela Tam","is_ca":false},{"name":"Nina Thiessen","is_ca":false},{"name":"Kane Tse","is_ca":false},{"name":"Tina Wong","is_ca":false},{"name":"Rameen Beroukhim","is_ca":false},{"name":"Carrie Cibulskis","is_ca":false},{"name":"Stacey B. Gabriel","is_ca":false},{"name":"Galen F. Gao","is_ca":false},{"name":"Gavin Ha","is_ca":false},{"name":"Matthew Meyerson","is_ca":false},{"name":"Steven E. Schumacher","is_ca":false},{"name":"Juliann Shih","is_ca":false},{"name":"Melanie H. Kucherlapati","is_ca":false},{"name":"Raju Kucherlapati","is_ca":false},{"name":"Stephen B. Baylin","is_ca":false},{"name":"Leslie Cope","is_ca":false},{"name":"Ludmila Danilova","is_ca":false},{"name":"Moiz Bootwalla","is_ca":false},{"name":"Phillip H. Lai","is_ca":false},{"name":"Dennis T. Maglinte","is_ca":false},{"name":"David Van Den Berg","is_ca":false},{"name":"Daniel J. Weisenberger","is_ca":false},{"name":"J. Todd Auman","is_ca":false},{"name":"Saianand Balu","is_ca":false},{"name":"Tom Bodenheimer","is_ca":false},{"name":"Katherine A. Hoadley","is_ca":false},{"name":"Alan P. Hoyle","is_ca":false},{"name":"Corbin D. Jones","is_ca":false},{"name":"Shaowu Meng","is_ca":false},{"name":"Piotr A. Mieczkowski","is_ca":false},{"name":"Lisle E. Mose","is_ca":false},{"name":"Amy H. Perou","is_ca":false},{"name":"Charles M. Perou","is_ca":false},{"name":"Jeffrey Roach","is_ca":false},{"name":"Yan Shi","is_ca":false},{"name":"Janae V. Simons","is_ca":false},{"name":"Tara Skelly","is_ca":false},{"name":"Matthew G. Soloway","is_ca":false},{"name":"Donghui Tan","is_ca":false},{"name":"Umadevi Veluvolu","is_ca":false},{"name":"Huihui Fan","is_ca":false},{"name":"Toshinori Hinoue","is_ca":false},{"name":"Peter W. Laird","is_ca":false},{"name":"Hui Shen","is_ca":false},{"name":"Wanding Zhou","is_ca":false},{"name":"Michelle Bellair","is_ca":false},{"name":"Kyle Chang","is_ca":false},{"name":"Kyle R. Covington","is_ca":false},{"name":"Chad J. Creighton","is_ca":false},{"name":"Huyen Dinh","is_ca":false},{"name":"HarshaVardhan Doddapaneni","is_ca":false},{"name":"Lawrence A. Donehower","is_ca":false},{"name":"Jennifer Drummond","is_ca":false},{"name":"Richard A. Gibbs","is_ca":false},{"name":"Robert Glenn","is_ca":false},{"name":"Walker Hale","is_ca":false},{"name":"Yi Han","is_ca":false},{"name":"Hai Hu","is_ca":true},{"name":"Viktoriya Korchina","is_ca":false},{"name":"Lora Lewis","is_ca":false},{"name":"Wei Li","is_ca":false},{"name":"Xiuping Liu","is_ca":false},{"name":"Margaret Morgan","is_ca":false},{"name":"Donna Morton","is_ca":false},{"name":"Donna M. Muzny","is_ca":false},{"name":"Jireh Santibanez","is_ca":false},{"name":"Margi Sheth","is_ca":false},{"name":"Eve Shinbrot","is_ca":false},{"name":"Linghua Wang","is_ca":false},{"name":"Min Wang","is_ca":false},{"name":"David A. Wheeler","is_ca":false},{"name":"Liu Xi","is_ca":false},{"name":"Fengmei Zhao","is_ca":false},{"name":"Julian M. Hess","is_ca":false},{"name":"Elizabeth L. Appelbaum","is_ca":false},{"name":"Matthew H. Bailey","is_ca":false},{"name":"Matthew G. Cordes","is_ca":false},{"name":"Li Ding","is_ca":false},{"name":"Catrina C. Fronick","is_ca":false},{"name":"Lucinda A. Fulton","is_ca":false},{"name":"Robert S. Fulton","is_ca":false},{"name":"Cyriac Kandoth","is_ca":false},{"name":"Elaine R. Mardis","is_ca":false},{"name":"Michael D. McLellan","is_ca":true},{"name":"Christopher A. Miller","is_ca":false},{"name":"Heather K. Schmidt","is_ca":false},{"name":"Richard K. Wilson","is_ca":false},{"name":"Daniel Crain","is_ca":false},{"name":"Erin Curley","is_ca":false},{"name":"Johanna Gardner","is_ca":false},{"name":"Kevin Lau","is_ca":false},{"name":"David Mallery","is_ca":false},{"name":"Scott Morris","is_ca":false},{"name":"Joseph Paulauskis","is_ca":false},{"name":"Robert Penny","is_ca":false},{"name":"Candace Shelton","is_ca":false},{"name":"Troy Shelton","is_ca":false},{"name":"Mark E. Sherman","is_ca":true},{"name":"Eric M. Thompson","is_ca":false},{"name":"Peggy Yena","is_ca":false},{"name":"Jay Bowen","is_ca":false},{"name":"Julie M. Gastier‐Foster","is_ca":false},{"name":"Mark Gerken","is_ca":false},{"name":"Kristen Leraas","is_ca":false},{"name":"Tara M. Lichtenberg","is_ca":false},{"name":"Nilsa C. Ramirez","is_ca":false},{"name":"Lisa Wise","is_ca":false},{"name":"Erik Zmuda","is_ca":false},{"name":"Niall M. Corcoran","is_ca":false},{"name":"Tony Costello","is_ca":false},{"name":"Christopher M. Hovens","is_ca":false},{"name":"André Lopes Carvalho","is_ca":false},{"name":"Ana Carolina de Carvalho","is_ca":false},{"name":"José Humberto Tavares Guerreiro Fregnani","is_ca":false},{"name":"Adhemar Longatto‐Filho","is_ca":false},{"name":"Rui Manuel Reis","is_ca":false},{"name":"Cristovam Scapulatempo‐Neto","is_ca":false},{"name":"Henrique C.S. Silveira","is_ca":false},{"name":"Daniel Onofre Vidal","is_ca":false},{"name":"Andrew Burnette","is_ca":false},{"name":"Jennifer Eschbacher","is_ca":false},{"name":"Beth Hermes","is_ca":false},{"name":"Ardene Noss","is_ca":false},{"name":"Rosy Singh","is_ca":false},{"name":"Matthew L. Anderson","is_ca":false},{"name":"Patricia D. Castro","is_ca":false},{"name":"Michael Ittmann","is_ca":false},{"name":"David G. Huntsman","is_ca":false},{"name":"Bernard Kohl","is_ca":false},{"name":"Xuan Le","is_ca":false},{"name":"Richard Thorp","is_ca":false},{"name":"Chris Andry","is_ca":false},{"name":"Elizabeth R. Duffy","is_ca":false},{"name":"Vladimir Lyadov","is_ca":false},{"name":"Oxana Paklina","is_ca":false},{"name":"Galiya Setdikova","is_ca":false},{"name":"Shabunin Av","is_ca":false},{"name":"Mikhail Tavobilov","is_ca":false},{"name":"Christopher McPherson","is_ca":false},{"name":"Ronald E. Warnick","is_ca":false},{"name":"Ross S. Berkowitz","is_ca":false},{"name":"Daniel W. Cramer","is_ca":false},{"name":"Colleen M. Feltmate","is_ca":false},{"name":"Neil S. Horowitz","is_ca":false},{"name":"Adam S. Kibel","is_ca":false},{"name":"Michael G. Muto","is_ca":false},{"name":"Chandrajit P. Raut","is_ca":false},{"name":"Andrei Malykh","is_ca":false},{"name":"Jill S. Barnholtz‐Sloan","is_ca":false},{"name":"Wendi Barrett","is_ca":false},{"name":"Karen Devine","is_ca":false},{"name":"Jordonna Fulop","is_ca":false},{"name":"Quinn T. Ostrom","is_ca":false},{"name":"Kristen Shimmel","is_ca":false},{"name":"Yingli Wolinsky","is_ca":false},{"name":"Andrew E. Sloan","is_ca":false},{"name":"Agostino Maria De Rose","is_ca":false},{"name":"Felice Giuliante","is_ca":false},{"name":"Marc T. Goodman","is_ca":false},{"name":"Beth Y. Karlan","is_ca":false},{"name":"Curt H. Hagedorn","is_ca":false},{"name":"John Eckman","is_ca":false},{"name":"Jodi Harr","is_ca":false},{"name":"Jerome Myers","is_ca":false},{"name":"Kelinda Tucker","is_ca":false},{"name":"Leigh Anne Zach","is_ca":false},{"name":"Brenda Deyarmin","is_ca":false},{"name":"Leonid Kvecher","is_ca":false},{"name":"Caroline Larson","is_ca":false},{"name":"Richard Mural","is_ca":false},{"name":"Stella Somiari","is_ca":false},{"name":"Aleš Vícha","is_ca":false},{"name":"Tomáš Zelinka","is_ca":false},{"name":"Mary Iacocca","is_ca":false},{"name":"Brenda Rabeno","is_ca":false},{"name":"Patricia Swanson","is_ca":false},{"name":"Mathieu Latour","is_ca":false},{"name":"Louis Lacombe","is_ca":false},{"name":"Bernard Têtu","is_ca":false},{"name":"Alain Bergeron","is_ca":false},{"name":"Mary McGraw","is_ca":false},{"name":"Susan M. Staugaitis","is_ca":false},{"name":"John A. Chabot","is_ca":false},{"name":"Hanina Hibshoosh","is_ca":false},{"name":"Antonia R. Sepulveda","is_ca":false},{"name":"Tao Su","is_ca":false},{"name":"Timothy C. Wang","is_ca":false},{"name":"Olga Potapova","is_ca":false},{"name":"Olga L. Voronina","is_ca":false},{"name":"Laurence Desjardins","is_ca":false},{"name":"Odette Mariani","is_ca":false},{"name":"Sergio Roman‐Roman","is_ca":false},{"name":"Xavier Sastre","is_ca":false},{"name":"Marc‐Henri Stern","is_ca":false},{"name":"Feixiong Cheng","is_ca":false},{"name":"Sabina Signoretti","is_ca":false},{"name":"Andrew Berchuck","is_ca":false},{"name":"Darell D. Bigner","is_ca":false},{"name":"Eric Lipp","is_ca":false},{"name":"Jeffrey S. Marks","is_ca":false},{"name":"Shannon J. McCall","is_ca":false},{"name":"Roger E. McLendon","is_ca":false},{"name":"Angeles Alvarez Secord","is_ca":false},{"name":"Alexis Sharp","is_ca":false},{"name":"Madhusmita Behera","is_ca":false},{"name":"Daniel J. Brat","is_ca":false},{"name":"Amy Chen","is_ca":false},{"name":"Keith A. Delman","is_ca":false},{"name":"Seth Force","is_ca":false},{"name":"Fadlo R. Khuri","is_ca":false},{"name":"Kelly R. Magliocca","is_ca":false},{"name":"Shishir K. Maithel","is_ca":false},{"name":"Jeffrey J. Olson","is_ca":false},{"name":"Taofeek K. Owonikoko","is_ca":false},{"name":"Alan Pickens","is_ca":false},{"name":"Suresh S. Ramalingam","is_ca":false},{"name":"Dong Min Shin","is_ca":false},{"name":"Gabriel Sica","is_ca":false},{"name":"Erwin G. Van Meir","is_ca":false},{"name":"Hongzheng Zhang","is_ca":false},{"name":"Wil Eijckenboom","is_ca":false},{"name":"Ad Gillis","is_ca":false},{"name":"Esther Korpershoek","is_ca":false},{"name":"Leendert H. J. Looijenga","is_ca":false},{"name":"Wolter Oosterhuis","is_ca":false},{"name":"Hans Stoop","is_ca":false},{"name":"Kim E. van Kessel","is_ca":false},{"name":"Ellen C. Zwarthoff","is_ca":false},{"name":"Chiara Calatozzolo","is_ca":false},{"name":"Lucia Cuppini","is_ca":false},{"name":"Stefania Cuzzubbo","is_ca":false},{"name":"Francesco DiMeco","is_ca":false},{"name":"Gaetano Finocchiaro","is_ca":false},{"name":"Luca Mattei","is_ca":false},{"name":"Alessandro Perin","is_ca":false},{"name":"Bianca Pollo","is_ca":false},{"name":"Chen Chu","is_ca":false},{"name":"J. C. Houck","is_ca":false},{"name":"Pawadee Lohavanichbutr","is_ca":false},{"name":"Arndt Hartmann","is_ca":false},{"name":"Robert Stoehr","is_ca":false},{"name":"Helge Täubert","is_ca":false},{"name":"Sven Wach","is_ca":false},{"name":"Bernd Wullich","is_ca":true},{"name":"Witold Kycler","is_ca":false},{"name":"Dawid Murawa","is_ca":false},{"name":"Ki Wung Chung","is_ca":false},{"name":"W. Jeffrey Edenfield","is_ca":false},{"name":"Julie Martin","is_ca":false},{"name":"Éric Baudin","is_ca":false},{"name":"Glenn J. Bubley","is_ca":false},{"name":"Raphael Bueno","is_ca":false},{"name":"Assunta De Rienzo","is_ca":false},{"name":"William G. Richards","is_ca":false},{"name":"Steven N. Kalkanis","is_ca":false},{"name":"Tom Mikkelsen","is_ca":false},{"name":"Houtan Noushmehr","is_ca":false},{"name":"Lisa Scarpace","is_ca":false},{"name":"Nicolas Girard","is_ca":false},{"name":"Marta Aymerich","is_ca":false},{"name":"Elı́as Campo","is_ca":false},{"name":"Eva Giné","is_ca":false},{"name":"Armando López Guillermo","is_ca":false},{"name":"Nguyen Van Bang","is_ca":false},{"name":"Phan Thi Hanh","is_ca":false},{"name":"Bùi Đức Phú","is_ca":false},{"name":"Yufang Tang","is_ca":false},{"name":"Howard Colman","is_ca":false},{"name":"Kimberley Evason","is_ca":false},{"name":"Peter R. Dottino","is_ca":false},{"name":"John A. Martignetti","is_ca":false},{"name":"Hani Gabra","is_ca":false},{"name":"Hartmut Juhl","is_ca":false},{"name":"Teniola Akeredolu","is_ca":false},{"name":"Serghei Stepa","is_ca":false},{"name":"Dave S.�B. Hoon","is_ca":false},{"name":"Keunsoo Ahn","is_ca":false},{"name":"Koo Jeong Kang","is_ca":false},{"name":"Felix Beuschlein","is_ca":false},{"name":"Anne Breggia","is_ca":false},{"name":"Michael J. Birrer","is_ca":false},{"name":"Debra Bell","is_ca":false},{"name":"Mitesh J. Borad","is_ca":false},{"name":"Alan H. Bryce","is_ca":false},{"name":"Erik P. Castle","is_ca":false},{"name":"Vishal S. Chandan","is_ca":false},{"name":"John C. Cheville","is_ca":false},{"name":"John A. Copland","is_ca":false},{"name":"Michael B. Farnell","is_ca":false},{"name":"Thomas J. Flotte","is_ca":false},{"name":"Nasra H. Giama","is_ca":false},{"name":"Thai H. Ho","is_ca":false},{"name":"Michael L. Kendrick","is_ca":false},{"name":"Jean‐Pierre Kocher","is_ca":false},{"name":"Karla Kopp","is_ca":false},{"name":"Catherine D. Moser","is_ca":false},{"name":"David M. Nagorney","is_ca":false},{"name":"Daniel J. O’Brien","is_ca":false},{"name":"Brian Patrick O’Neill","is_ca":false},{"name":"Tushar Patel","is_ca":false},{"name":"Gloria Petersen","is_ca":false},{"name":"Florencia G. Que","is_ca":false},{"name":"Michael Rivera","is_ca":false},{"name":"Lewis R. Roberts","is_ca":false},{"name":"Robert C. Smallridge","is_ca":false},{"name":"Thomas C. Smyrk","is_ca":false},{"name":"Melissa Stanton","is_ca":true},{"name":"R. Houston Thompson","is_ca":true},{"name":"Michael Torbenson","is_ca":false},{"name":"Ju Dong Yang","is_ca":false},{"name":"Lizhi Zhang","is_ca":false},{"name":"Fadi Brimo","is_ca":false},{"name":"Ana Maria Angulo Gonzalez","is_ca":false},{"name":"Carmen Behrens","is_ca":false},{"name":"Jolanta Bondaruk","is_ca":false},{"name":"Russell R. Broaddus","is_ca":false},{"name":"Bogdan Czerniak","is_ca":false},{"name":"Bita Esmaeli","is_ca":false},{"name":"Junya Fujimoto","is_ca":false},{"name":"Charles Guo","is_ca":false},{"name":"Alexander J. Lazar","is_ca":false},{"name":"Christopher J. Logothetis","is_ca":false},{"name":"Funda Meric‐Bernstam","is_ca":false},{"name":"César A. Moran","is_ca":false},{"name":"Lois M. Ramondetta","is_ca":false},{"name":"David Rice","is_ca":false},{"name":"Anil K. Sood","is_ca":false},{"name":"Pheroze Tamboli","is_ca":false},{"name":"Timothy Thompson","is_ca":false},{"name":"Patricia Troncoso","is_ca":false},{"name":"Anne S. Tsao","is_ca":false},{"name":"Ignacio Wistuba","is_ca":false},{"name":"Candace Carter","is_ca":false},{"name":"Lauren E. Haydu","is_ca":false},{"name":"Peter Hersey","is_ca":false},{"name":"Valerie Jakrot","is_ca":false},{"name":"Hojabr Kakavand","is_ca":false},{"name":"Richard Kefford","is_ca":false},{"name":"Kenneth Lee","is_ca":false},{"name":"Georgina V. Long","is_ca":false},{"name":"Graham J. Mann","is_ca":false},{"name":"Michael Quinn","is_ca":false},{"name":"Robyn P.M. Saw","is_ca":false},{"name":"Richard A. Scolyer","is_ca":false},{"name":"Kerwin F. Shannon","is_ca":false},{"name":"Andrew J. Spillane","is_ca":false},{"name":"Jonathan R. Stretch","is_ca":false},{"name":"Maria Synott","is_ca":false},{"name":"John Thompson","is_ca":false},{"name":"James S. Wilmott","is_ca":false},{"name":"Hikmat Al‐Ahmadie","is_ca":false},{"name":"Timothy A. Chan","is_ca":false},{"name":"Ronald Ghossein","is_ca":false},{"name":"Anuradha Gopalan","is_ca":false},{"name":"Douglas A. Levine","is_ca":false},{"name":"Victor Reuter","is_ca":false},{"name":"Samuel Singer","is_ca":false},{"name":"Bhuvanesh Singh","is_ca":false},{"name":"Nguyen Viet Tien","is_ca":false},{"name":"Thomas Broudy","is_ca":false},{"name":"Cyrus Mirsaidi","is_ca":false},{"name":"Praveen Nair","is_ca":false},{"name":"Paul Drwiega","is_ca":false},{"name":"Jennifer R. Smith","is_ca":false},{"name":"Howard Zaren","is_ca":false},{"name":"Joong‐Won Park","is_ca":false},{"name":"Nguyễn Phi Hùng","is_ca":false},{"name":"Electron Kebebew","is_ca":false},{"name":"W. Marston Linehan","is_ca":false},{"name":"Adam R. Metwalli","is_ca":false},{"name":"Karel Pacák","is_ca":false},{"name":"Peter A. Pinto","is_ca":false},{"name":"Mark Schiffman","is_ca":false},{"name":"Laura S. Schmidt","is_ca":false},{"name":"Cathy D. Vocke","is_ca":false},{"name":"Nicolas Wentzensen","is_ca":false},{"name":"Robert Worrell","is_ca":false},{"name":"Hannah Yang","is_ca":false},{"name":"Marc Moncrieff","is_ca":false},{"name":"Chandra Goparaju","is_ca":true},{"name":"Jonathan Melamed","is_ca":false},{"name":"Harvey I. Pass","is_ca":false},{"name":"Natalia Botnariuc","is_ca":false},{"name":"Irina Caraman","is_ca":false},{"name":"Mircea Cernat","is_ca":false},{"name":"Inga Chemencedji","is_ca":false},{"name":"Adrian Clipca","is_ca":false},{"name":"Serghei Doruc","is_ca":false},{"name":"Ghenadie Gorincioi","is_ca":false},{"name":"Sergiu Mura","is_ca":false},{"name":"Maria Pirtac","is_ca":false},{"name":"Irina Stancul","is_ca":false},{"name":"Diana Tcaciuc","is_ca":false},{"name":"Monique Albert","is_ca":false},{"name":"Iakovina Alexopoulou","is_ca":false},{"name":"Angel Arnaout","is_ca":false},{"name":"John Bartlett","is_ca":false},{"name":"Jay Engel","is_ca":false},{"name":"Sébastien Gilbert","is_ca":false},{"name":"Jeremy Parfitt","is_ca":false},{"name":"Harman Sekhon","is_ca":false},{"name":"George Thomas","is_ca":false},{"name":"Doris M. Rassl","is_ca":false},{"name":"Robert C. Rintoul","is_ca":false},{"name":"Carlo Bifulco","is_ca":false},{"name":"Raina Tamakawa","is_ca":false},{"name":"Walter J. Urba","is_ca":false},{"name":"Nicholas K. Hayward","is_ca":false},{"name":"Henri Timmers","is_ca":false},{"name":"Anna Antenucci","is_ca":false},{"name":"Francesco Facciolo","is_ca":false},{"name":"Gian Luca Grazi","is_ca":false},{"name":"Mirella Marino","is_ca":false},{"name":"Roberta Merola","is_ca":false},{"name":"Ronald R. de Krijger","is_ca":false},{"name":"Anne‐Paule Gimenez‐Roqueplo","is_ca":false},{"name":"Alain Piché","is_ca":false},{"name":"Simone Chevalier","is_ca":false},{"name":"Ginette McKercher","is_ca":false},{"name":"Kıvanç Birsoy","is_ca":false},{"name":"Gene H. Barnett","is_ca":false},{"name":"Cathy Brewer","is_ca":false},{"name":"Carol Farver","is_ca":false},{"name":"Theresa Naska","is_ca":false},{"name":"Nathan A. Pennell","is_ca":false},{"name":"Daniel Raymond","is_ca":false},{"name":"Cathy Schilero","is_ca":false},{"name":"Kathy Smolenski","is_ca":false},{"name":"Quaid Morris","is_ca":false},{"name":"Jeffrey A. Borgia","is_ca":false},{"name":"Mark Pool","is_ca":false},{"name":"Christopher W. Seder","is_ca":false},{"name":"Kerstin Junker","is_ca":false},{"name":"Larsson Omberg","is_ca":false},{"name":"Mikhail Dinkin","is_ca":false},{"name":"George Manikhas","is_ca":false},{"name":"Domenico Alvaro","is_ca":false},{"name":"Maria Consiglia Bragazzi","is_ca":false},{"name":"Vincenzo Cardinale","is_ca":false},{"name":"Guido Carpino","is_ca":false},{"name":"Eugenio Gaudio","is_ca":false},{"name":"David Chesla","is_ca":false},{"name":"Sandra Cottingham","is_ca":false},{"name":"Michael Dubina","is_ca":false},{"name":"Fedor Moiseenko","is_ca":false},{"name":"Renumathy Dhanasekaran","is_ca":false},{"name":"Karl‐Friedrich Becker","is_ca":false},{"name":"Klaus‐Peter Janssen","is_ca":false},{"name":"Julia Slotta‐Huspenina","is_ca":false},{"name":"Mohamed H. Abdel‐Rahman","is_ca":false},{"name":"Dina Aziz","is_ca":false},{"name":"Sue Bell","is_ca":false},{"name":"Colleen M. Cebulla","is_ca":false},{"name":"Amy Davis","is_ca":false},{"name":"Rebecca Duell","is_ca":false},{"name":"J. Bradley Elder","is_ca":false},{"name":"Joe Hilty","is_ca":false},{"name":"Bahavna Kumar","is_ca":false},{"name":"James C. Lang","is_ca":false},{"name":"Norman L. Lehman","is_ca":false},{"name":"Randy Mandt","is_ca":false},{"name":"Phuong Nguyen","is_ca":false},{"name":"Robert Pilarski","is_ca":false},{"name":"Karan Rai","is_ca":false},{"name":"Lynn Schoenfield","is_ca":false},{"name":"Kelly Senecal","is_ca":true},{"name":"Paul E. Wakely","is_ca":false},{"name":"Paul Hansen","is_ca":false},{"name":"Ronald M. Lechan","is_ca":false},{"name":"James F. Powers","is_ca":false},{"name":"Arthur S. Tischler","is_ca":false},{"name":"William E. Grizzle","is_ca":false},{"name":"Katherine C. Sexton","is_ca":false},{"name":"Alison Kastl","is_ca":false},{"name":"Joel Henderson","is_ca":false},{"name":"Sima P. Porten","is_ca":false},{"name":"Jens Waldmann","is_ca":false},{"name":"Martin Faßnacht","is_ca":false},{"name":"L. Sylvia","is_ca":false},{"name":"Dirk Schadendorf","is_ca":false},{"name":"Marta Couce","is_ca":false},{"name":"Markus Graefen","is_ca":false},{"name":"Hartwig Huland","is_ca":false},{"name":"Guido Sauter","is_ca":false},{"name":"Thorsten Schlomm","is_ca":false},{"name":"Ronald Simon","is_ca":false},{"name":"Pierre Tennstedt","is_ca":false},{"name":"Oluwole Olabode","is_ca":false},{"name":"Mark A. Nelson","is_ca":false},{"name":"Oliver F. Bathe","is_ca":false},{"name":"Peter R. Carroll","is_ca":false},{"name":"June M. Chan","is_ca":false},{"name":"Philip J. DiSaia","is_ca":false},{"name":"Pat Glenn","is_ca":false},{"name":"Robin Kate Kelley","is_ca":false},{"name":"Charles N. Landen","is_ca":false},{"name":"Joanna Phillips","is_ca":false},{"name":"Michael D. Prados","is_ca":false},{"name":"Jeffry Simko","is_ca":false},{"name":"Karen Smith‐McCune","is_ca":false},{"name":"Scott Vandenberg","is_ca":false},{"name":"Kevin K. Roggin","is_ca":false},{"name":"Ashley Fehrenbach","is_ca":false},{"name":"Ady Kendler","is_ca":false},{"name":"Suzanne Sifri","is_ca":false},{"name":"Ruth Steele","is_ca":false},{"name":"Antonio Jimeno","is_ca":false},{"name":"Francis A. Carey","is_ca":false},{"name":"Ian Forgie","is_ca":false},{"name":"Massimo Mannelli","is_ca":false},{"name":"Michael E. Carney","is_ca":false},{"name":"Brenda Hernandez","is_ca":false},{"name":"Benito Campos","is_ca":false},{"name":"Christel Herold‐Mende","is_ca":false},{"name":"Christin Jungk","is_ca":false},{"name":"Andreas Unterberg","is_ca":false},{"name":"Andreas von Deimling","is_ca":false},{"name":"Aaron Bossler","is_ca":false},{"name":"Joseph Galbraith","is_ca":false},{"name":"Laura Jacobus","is_ca":false},{"name":"Michael Knudson","is_ca":false},{"name":"Tina Knutson","is_ca":false},{"name":"Deqin Ma","is_ca":false},{"name":"Mohammed Milhem","is_ca":false},{"name":"Rita Sigmund","is_ca":false},{"name":"Andrew K. Godwin","is_ca":false},{"name":"Rashna Madan","is_ca":false},{"name":"Howard G. Rosenthal","is_ca":false},{"name":"Clement Adebamowo","is_ca":false},{"name":"Sally N. Adebamowo","is_ca":false},{"name":"Alex Boussioutas","is_ca":false},{"name":"David G. Beer","is_ca":false},{"name":"Thomas J. Giordano","is_ca":false},{"name":"Anne‐Marie Mes‐Masson","is_ca":false},{"name":"Fred Saad","is_ca":false},{"name":"Thèrése Bocklage","is_ca":false},{"name":"Lisa M. Landrum","is_ca":false},{"name":"Robert S. Mannel","is_ca":false},{"name":"Kathleen Moore","is_ca":false},{"name":"Katherine Moxley","is_ca":false},{"name":"Russel Postier","is_ca":true},{"name":"Joan Walker","is_ca":false},{"name":"Rosemary E. Zuna","is_ca":false},{"name":"Michael D. Feldman","is_ca":false},{"name":"Federico Valdivieso","is_ca":false},{"name":"Rajiv Dhir","is_ca":false},{"name":"James D. Luketich","is_ca":false},{"name":"Edna M. Mora Pinero","is_ca":false},{"name":"Mario Quintero-Aguilo","is_ca":false},{"name":"Carlos Gilberto Carlotti","is_ca":false},{"name":"José Sebastião dos Santos","is_ca":false},{"name":"Rafael Kemp","is_ca":false},{"name":"Ajith Sankarankuty","is_ca":false},{"name":"Daniela Pretti da Cunha Tirapelli","is_ca":false},{"name":"James W.F. Catto","is_ca":false},{"name":"Kathy Agnew","is_ca":false},{"name":"Elizabeth M. Swisher","is_ca":false},{"name":"Jenette Creaney","is_ca":false},{"name":"Bruce Robinson","is_ca":false},{"name":"Carl Simon Shelley","is_ca":false},{"name":"Eryn M. Godwin","is_ca":false},{"name":"Sara Kendall","is_ca":false},{"name":"Cassaundra Shipman","is_ca":false},{"name":"Carol R. Bradford","is_ca":false},{"name":"Thomas E. Carey","is_ca":false},{"name":"Jeffey Moyer","is_ca":false},{"name":"Lisa A. Peterson","is_ca":false},{"name":"Mark E. Prince","is_ca":false},{"name":"Laura S. Rozek","is_ca":false},{"name":"Gregory T. Wolf","is_ca":false},{"name":"Rayleen Bowman","is_ca":false},{"name":"Kwun M. Fong","is_ca":false},{"name":"Ian A. Yang","is_ca":false},{"name":"Robert J. Korst","is_ca":false},{"name":"W. Kimryn Rathmell","is_ca":false},{"name":"J. Leigh Fantacone-Campbell","is_ca":false},{"name":"Jeffrey A. Hooke","is_ca":true},{"name":"Albert J. Kovatich","is_ca":false},{"name":"Craig D. Shriver","is_ca":false},{"name":"John F. DiPersio","is_ca":false},{"name":"Bettina F. Drake","is_ca":false},{"name":"Ramaswamy Govindan","is_ca":false},{"name":"Sharon E. Heath","is_ca":false},{"name":"Timothy J. Ley","is_ca":false},{"name":"Brian A. Van Tine","is_ca":false},{"name":"Peter Westervelt","is_ca":false},{"name":"Mark A. Rubin","is_ca":false},{"name":"Jung Il Lee","is_ca":false},{"name":"Natália D. Aredes","is_ca":false},{"name":"Armaz Mariamidze","is_ca":false},{"name":"Lopa Mishra","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00782757285774283,"gpt":0.2412351292604774,"spread":0.2334075564027346,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002666288,0.0001367823,0.0002475556,0.000111707,0.00005201536,0.00002470243,0.0002847478,0.0001100306,0.0000329673],"category_scores_gemma":[0.00004925381,0.0001097212,0.00008738525,0.0004511988,0.0001055533,0.000003629566,0.00003861735,0.00005898493,0.00000703018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002993921,"about_ca_system_score_gemma":0.00009593477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001731847,"about_ca_topic_score_gemma":0.0004932633,"domain_scores_codex":[0.9985948,0.0002099133,0.0004916374,0.0003136723,0.0001667872,0.000223192],"domain_scores_gemma":[0.9992235,0.00004732956,0.0001514343,0.0004240616,0.0001019667,0.00005167134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001309276,0.00006100354,0.12798,0.00005488088,0.00009596926,0.000001380207,0.0002212385,0.002643919,0.8683462,0.000007134142,0.0005276769,0.00004756086],"study_design_scores_gemma":[0.001042158,0.0001979451,0.06640814,0.0001877937,0.0003957327,0.000001719941,0.000704036,0.001226219,0.9284633,0.00004844614,0.000832398,0.0004921091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985425,0.01332009,0.0005535499,0.0000173241,0.0001985037,0.0002629638,0.0000656458,0.000005726777,0.0001512269],"genre_scores_gemma":[0.999074,0.00009955218,0.00009584503,0.00004407231,0.0002693313,0.0001247988,0.00007162861,0.00001781584,0.0002029611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06157184,"threshold_uncertainty_score":0.4474299,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1969619516","doi":"10.1158/0008-5472.can-06-3117","title":"The Type III Transforming Growth Factor-β Receptor as a Novel Tumor Suppressor Gene in Prostate Cancer","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Prostate cancer; Prostate; Cancer research; Biology; Cancer; Internal medicine; Tumor progression; Endocrinology; Medicine","authors":[{"name":"Ryan S. Turley","is_ca":true},{"name":"Elizabeth Finger","is_ca":false},{"name":"Nadine Hempel","is_ca":false},{"name":"Tam How","is_ca":false},{"name":"Timothy A. Fields","is_ca":false},{"name":"Gerard C. Blobe","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04101904145204979,"gpt":0.3809138062298688,"spread":0.339894764777819,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007636315,0.000146313,0.0001240202,0.00008705802,0.0002516476,0.00005878022,0.0004312245,0.000080138,0.0001583714],"category_scores_gemma":[0.0002481618,0.0001128263,0.00005245121,0.0003518487,0.0002253968,0.000007898242,0.0001082845,0.0003058291,0.000015572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001495985,"about_ca_system_score_gemma":0.0008368086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001478051,"about_ca_topic_score_gemma":0.002166481,"domain_scores_codex":[0.9980894,0.00006875626,0.0002461349,0.0004027926,0.0004287343,0.0007641515],"domain_scores_gemma":[0.9990264,0.00008594213,0.00004161456,0.0002976931,0.0003822881,0.0001661302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001186811,0.0000560938,0.003578093,0.00004035192,0.00003852048,0.000009548558,0.0003427732,0.00002858361,0.9909465,0.00002983478,0.001301171,0.002441675],"study_design_scores_gemma":[0.0007453376,0.0001217198,0.002701588,0.00005662013,0.000003778519,0.000002532045,0.0001816575,0.000005422376,0.9375721,0.00002443815,0.05843105,0.0001537509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909641,0.007553097,0.00004206776,0.0002782946,0.0002255412,0.0005397736,0.00009155885,0.00001252697,0.0002930625],"genre_scores_gemma":[0.9964038,0.001078885,0.00005632062,0.0001032505,0.0003712095,0.0002665615,0.00003277284,0.00004270967,0.001644453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05712987,"threshold_uncertainty_score":0.4600922,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2107942632","doi":"10.1242/dev.127.14.3079","title":"Formation of the definitive endoderm in mouse is a Smad2-dependent process","year":2000,"lang":"en","type":"article","venue":"Development","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Biology; Epiblast; Gastrulation; Endoderm; Nodal signaling; Primitive streak; Cell biology; NODAL; Fate mapping; Cell fate determination; Ectoderm; Germ layer; Population; Embryo; Embryonic stem cell; Genetics; Embryogenesis; Stem cell; Gene; Induced pluripotent stem cell; Transcription factor; Progenitor cell","authors":[{"name":"Kimberly D. Tremblay","is_ca":false},{"name":"Pamela A. Hoodless","is_ca":true},{"name":"Elizabeth K. Bikoff","is_ca":false},{"name":"Elizabeth J. Robertson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01078655319527891,"gpt":0.2332938430875395,"spread":0.2225072898922606,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006865811,0.00007843762,0.00006497157,0.00002156084,0.00003853784,0.000006553539,0.0001430475,0.00004725901,0.00006684591],"category_scores_gemma":[0.00001897938,0.00006205776,0.00002575357,0.00005439941,0.00002311323,0.000003427683,0.00003759113,0.00003552565,0.00001307421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002337251,"about_ca_system_score_gemma":0.0001666541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004911128,"about_ca_topic_score_gemma":0.00003990761,"domain_scores_codex":[0.9993886,0.00002206683,0.0001979785,0.0001330521,0.0001395434,0.0001186967],"domain_scores_gemma":[0.9997486,0.000004301708,0.00005361535,0.0001317248,0.00003809571,0.00002360131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009203749,0.001851666,0.06815726,0.0006809991,0.0002667692,0.00001543347,0.03813109,0.002812316,0.7364841,0.00008878189,0.002392911,0.1481983],"study_design_scores_gemma":[0.000332137,0.00001381593,0.009504329,0.00002963291,0.000003026501,0.000002618787,0.0001394883,0.00001613221,0.9864228,0.00002651296,0.003423362,0.00008617683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998272,0.0001419775,0.0000928044,0.00003019796,0.00001721846,0.000161485,0.00001170793,0.000004958583,0.001267649],"genre_scores_gemma":[0.9986938,0.00001802441,0.0002930957,0.0002251186,0.00001050392,0.00005646951,0.00003746929,0.000007707256,0.0006578358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2499387,"threshold_uncertainty_score":0.2530642,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2100075044","doi":"10.1007/s00018-011-0751-1","title":"BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain","year":2011,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Mount Sinai Hospital","funders":"Leids Universitair Medisch Centrum; Ludwig Institute for Cancer Research","keywords":"Cell biology; Biology; Furin; Phosphorylation; Receptor; Hepatocyte; Cytokine; Serine; Endogeny; Internal medicine; Endocrinology; Molecular biology; Immunology; Biochemistry; In vitro; Medicine","authors":[{"name":"Marie Bidart","is_ca":false},{"name":"Nicolas Ricard","is_ca":false},{"name":"Sandrine Levet","is_ca":false},{"name":"Michel Samson","is_ca":false},{"name":"Christine Mallet","is_ca":false},{"name":"Laurent David","is_ca":true},{"name":"Mariela Subileau","is_ca":false},{"name":"Emmanuelle Tillet","is_ca":false},{"name":"Jean‐Jacques Feige","is_ca":false},{"name":"Sabine Bailly","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02357641168254837,"gpt":0.2547252251154413,"spread":0.231148813432893,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002816043,0.0002206516,0.000187484,0.0000889998,0.0001725765,0.00006396846,0.0002877837,0.0001171482,0.00001678462],"category_scores_gemma":[0.000124821,0.0001995818,0.00004003876,0.0001789703,0.000257492,0.00002465771,0.0001632947,0.00007695092,0.000003403932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008017998,"about_ca_system_score_gemma":0.000113031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002580636,"about_ca_topic_score_gemma":0.00001461434,"domain_scores_codex":[0.9983729,0.00008420458,0.0001936175,0.0007785,0.000204671,0.0003660732],"domain_scores_gemma":[0.9993111,0.000007948379,0.00005140644,0.0002627079,0.00006601646,0.0003007971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007254913,0.00008804201,0.005695405,0.00003230581,0.00001759864,0.00001091995,0.0008281575,0.00000281965,0.9927039,0.00007982223,0.0001525243,0.0003159522],"study_design_scores_gemma":[0.0003158898,0.0003617741,0.004619155,0.00002733547,0.00001563386,0.000005656654,0.0003248247,0.0001103706,0.9929779,0.0002167386,0.0007249691,0.0002997286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938139,0.005079252,0.0002425726,0.0001208488,0.00004191675,0.0004942836,0.00003076416,0.00001697178,0.0001594837],"genre_scores_gemma":[0.9977626,0.00004436696,0.001173185,0.0008557831,0.00003418255,0.00004415209,0.00003881804,0.00001982495,0.00002711488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005034885,"threshold_uncertainty_score":0.8138711,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2108697952","doi":"10.1074/jbc.m107983200","title":"Early Endosomal Regulation of Smad-dependent Signaling in Endothelial Cells","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":182,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Endosome; SMAD; Cell biology; Endocytic cycle; Phosphorylation; Smad2 Protein; Signal transduction; Endocytosis; Biology; Signal transducing adaptor protein; Receptor; Biochemistry; Intracellular","authors":[{"name":"Ekaterini Panopoulou","is_ca":false},{"name":"David J. Gillooly","is_ca":false},{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Marino Zerial","is_ca":false},{"name":"Harald Stenmark","is_ca":false},{"name":"Carol Murphy","is_ca":false},{"name":"Theodore Fotsis","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01924513801417407,"gpt":0.2281003788293128,"spread":0.2088552408151387,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002306233,0.0001422706,0.0002490506,0.00003282626,0.00002297668,0.00001178416,0.0002681882,0.0002467435,0.0003021839],"category_scores_gemma":[0.0002073694,0.0001143942,0.00017786,0.00006506181,0.0000974519,0.00000554185,0.00006161263,0.0001803037,0.000003601682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002340161,"about_ca_system_score_gemma":0.00003324805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002105537,"about_ca_topic_score_gemma":2.673429e-7,"domain_scores_codex":[0.9987484,0.00006113782,0.0006021454,0.0001894003,0.0002045968,0.0001943202],"domain_scores_gemma":[0.9991482,0.00004767179,0.0004337915,0.0001574419,0.0001141766,0.00009872155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001945497,0.0002142861,0.009703667,0.00002557992,0.00003067738,0.00002077067,0.00002774843,0.0003205111,0.9888597,0.000001685002,0.00006380547,0.000537095],"study_design_scores_gemma":[0.0008233078,0.0002372981,0.006467517,0.00004789222,0.00001251148,0.00004223865,0.00003843866,0.0000317548,0.9917045,0.0000531221,0.0004183999,0.0001230296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982756,0.0009745691,0.0001048632,0.00001746929,0.00007228251,0.00004870305,0.00001990242,0.000004358249,0.0004822784],"genre_scores_gemma":[0.9987182,0.00008008948,0.000574589,0.00002341866,0.0004299087,0.00000200412,0.000008504641,0.00001015705,0.0001531223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003236151,"threshold_uncertainty_score":0.4664861,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2998177202","doi":"10.1016/j.semcdb.2019.11.013","title":"Non-canonical (non-SMAD2/3) TGF-β signaling in fibrosis: Mechanisms and targets","year":2019,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Biology; Signal transduction; Transforming growth factor; Non canonical; Fibrosis; Pathogenesis; Transforming growth factor beta; Cell biology; Computational biology; Cancer research; Immunology; Internal medicine","authors":[{"name":"Kenneth W. Finnson","is_ca":true},{"name":"Yasser Almadani","is_ca":true},{"name":"Anie Philip","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01493523307263504,"gpt":0.2748910162168538,"spread":0.2599557831442187,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003404612,0.0005663122,0.001141702,0.0002217724,0.00006397853,0.00002698778,0.0003080792,0.000931755,0.00003194587],"category_scores_gemma":[0.00004229437,0.0005103719,0.0001298417,0.0001514041,0.0001658777,0.000005405572,0.0006197084,0.0003368314,0.0000307606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008425018,"about_ca_system_score_gemma":0.0006518987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002022812,"about_ca_topic_score_gemma":0.00002460029,"domain_scores_codex":[0.9974715,0.0001245749,0.0007222604,0.001043885,0.00008721535,0.0005505312],"domain_scores_gemma":[0.999297,0.000113285,0.0002017915,0.0002265773,0.00001884957,0.0001424444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000356153,0.0006983184,0.009357398,0.02436339,0.0004072614,0.0002141454,0.0007990853,0.00001225125,0.2608605,0.00005466699,0.001962134,0.7009147],"study_design_scores_gemma":[0.002183829,0.0008113195,0.0003404044,0.01328026,0.0002306169,0.0002203713,0.0005207572,0.00001459215,0.04845948,0.0002598769,0.9311119,0.002566637],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03538655,0.9631495,0.00004820747,0.000003855288,0.0002312996,0.0006217156,0.00005540765,0.000008757736,0.0004946586],"genre_scores_gemma":[0.01908299,0.9734998,0.005723628,0.00009566536,0.00007265786,0.0001538445,0.0008808238,0.00006148395,0.0004291021],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9291497,"threshold_uncertainty_score":0.9997348,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124360065","doi":"10.1128/mcb.20.24.9346-9355.2000","title":"Hgs (Hrs), a FYVE Domain Protein, Is Involved in Smad Signaling through Cooperation with SARA","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Institute of Cancer Research","funders":"Core Research for Evolutional Science and Technology; Japan Science and Technology Agency; Japan Society for the Promotion of Science; Japan Science and Technology Corporation","keywords":"SMAD; Biology; Cell biology; Smad2 Protein; Mutant; Receptor; Signal transduction; Activin receptor; TGF beta receptor 2; Embryonic stem cell; Effector; Molecular biology; Genetics; Gene; TGF alpha; Growth factor","authors":[{"name":"Shigeto Miura","is_ca":false},{"name":"Toshikazu Takeshita","is_ca":false},{"name":"Hironobu Asao","is_ca":false},{"name":"Yutaka Kimura","is_ca":false},{"name":"Kazuko Murata","is_ca":false},{"name":"Yoshiteru Sasaki","is_ca":false},{"name":"Jun‐ichi Hanai","is_ca":true},{"name":"Hideyuki Beppu","is_ca":true},{"name":"Tomoo Tsukazaki","is_ca":false},{"name":"Jeffrey L. Wrana","is_ca":true},{"name":"Kohei Miyazono","is_ca":true},{"name":"Kazuo Sugamura","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006182701957217271,"gpt":0.2163737492495854,"spread":0.2101910472923682,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001673448,0.0002936041,0.000262603,0.00004302672,0.000107293,0.00003872765,0.0001814774,0.0002990698,0.0003900977],"category_scores_gemma":[0.00001625009,0.0002608712,0.00007337536,0.0001522902,0.0002170879,0.000008066529,0.00004827258,0.0001439044,0.00002542063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001565524,"about_ca_system_score_gemma":0.00009530596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000093612,"about_ca_topic_score_gemma":0.0000490099,"domain_scores_codex":[0.9982987,0.0002226068,0.0003016518,0.0006775677,0.0001018791,0.0003976194],"domain_scores_gemma":[0.9993981,0.000007751068,0.00006013855,0.0003785053,0.00006229209,0.00009324896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003105978,0.0001097783,0.001374018,0.00002950287,0.00006992727,0.00005883195,0.0002069872,0.0001754773,0.9948906,0.0001975642,0.00004738967,0.002529322],"study_design_scores_gemma":[0.001350438,0.0005878915,0.00007970566,0.00005031058,0.00002592135,0.00001412496,0.00006928612,0.00007136919,0.977854,0.0005644418,0.01893129,0.0004012208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884,0.004808408,0.005570613,0.0001402503,0.00001848046,0.0004764303,0.00001877132,0.00002348832,0.0005435289],"genre_scores_gemma":[0.9952832,0.00006537025,0.00260999,0.0009880872,0.00007580952,0.0001032651,0.0004441413,0.0000419376,0.0003882028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0188839,"threshold_uncertainty_score":0.9999843,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2974740020","doi":"10.1186/s13058-019-1194-0","title":"Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression","year":2019,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":175,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Beijing Key Laboratory of Green Recycling and Extraction of Metals; China Scholarship Council; China Sponsorship Council; Leids Universitair Medisch Centrum; Queen's University; Universiteit Leiden; Queen's University Belfast","keywords":"Breast cancer; Cancer research; Bone morphogenetic protein; Cancer; Epithelial–mesenchymal transition; Stromal cell; Biology; Medicine; Pathology; Metastasis; Internal medicine","authors":[{"name":"Jiang Ren","is_ca":false},{"name":"Marcel Smid","is_ca":false},{"name":"Josephine Iaria","is_ca":false},{"name":"Daniela Salvatori","is_ca":false},{"name":"Hans van Dam","is_ca":false},{"name":"Hong‐Jian Zhu","is_ca":false},{"name":"John W.M. Martens","is_ca":false},{"name":"Peter ten Dijke","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02457127677557405,"gpt":0.3699466645685853,"spread":0.3453753877930112,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005374293,0.0003472925,0.0003282814,0.0001503408,0.0002963984,0.0001271013,0.0006912751,0.0003239705,0.002245853],"category_scores_gemma":[0.00007371257,0.0003086878,0.0001478537,0.0005079022,0.0002782659,0.00002103911,0.0004890368,0.00044796,0.0001075478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003467108,"about_ca_system_score_gemma":0.001793317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003107531,"about_ca_topic_score_gemma":0.001358719,"domain_scores_codex":[0.9961879,0.0003611516,0.0003452665,0.0009834034,0.0009922313,0.001130076],"domain_scores_gemma":[0.9977959,0.00004648995,0.0001665479,0.0006567655,0.0009737553,0.0003604771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001067452,0.0003391474,0.112884,0.0002231497,0.0002329456,0.000008331056,0.0001002688,0.0002387879,0.8519168,0.000004788619,0.006049155,0.02693513],"study_design_scores_gemma":[0.002744088,0.0003656421,0.4105291,0.002215856,0.00004822537,0.00004874687,0.0001387783,0.0003918688,0.5756125,0.00004021653,0.006993012,0.0008719228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911766,0.003950482,0.000005195478,0.00181373,0.0002568967,0.001030129,0.001482939,0.00007469473,0.00020935],"genre_scores_gemma":[0.9949153,0.0004673377,0.00004699573,0.0001072553,0.0008082408,0.001030028,0.0001964304,0.0001124932,0.002315905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2976451,"threshold_uncertainty_score":0.9999365,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2114644843","doi":"10.1152/ajpheart.2000.279.6.h3020","title":"Interaction between angiotensin II and Smad proteins in fibroblasts in failing heart and in vitro","year":2000,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":175,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Losartan; SMAD; Angiotensin II; Internal medicine; Endocrinology; Fibrosis; Renin–angiotensin system; Cardiac fibrosis; Medicine; Chemistry; Transforming growth factor; Receptor; Blood pressure","authors":[{"name":"Jianming Hao","is_ca":true},{"name":"Baiqiu Wang","is_ca":true},{"name":"Stephen C. Jones","is_ca":true},{"name":"Davinder S. Jassal","is_ca":true},{"name":"Ian Dixon","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00805003301427569,"gpt":0.2434331874340249,"spread":0.2353831544197492,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002077641,0.0001999836,0.0005689377,0.0001962358,0.00005919248,0.000008398831,0.00008308792,0.0001296704,0.00001095818],"category_scores_gemma":[0.00003959434,0.0001945762,0.00006864129,0.0001483672,0.0004736699,0.00002553362,0.0000736577,0.0003145654,0.000001112276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002348299,"about_ca_system_score_gemma":0.00007287698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008282636,"about_ca_topic_score_gemma":0.00002834579,"domain_scores_codex":[0.9984772,0.0002844629,0.000446758,0.0004166157,0.00006540868,0.0003095574],"domain_scores_gemma":[0.9994581,0.00006105907,0.0001691996,0.0001646983,0.00003665169,0.0001103304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005967431,0.00008297284,0.02298628,0.00001858474,0.00002952352,9.45935e-7,0.000173439,0.0003475636,0.9738642,6.118701e-7,0.00001803966,0.001881068],"study_design_scores_gemma":[0.0008428362,0.000712814,0.9516749,0.0000852924,0.00001162155,0.00006433681,0.0001835343,0.00008622924,0.0454022,0.0001490557,0.0005982117,0.0001889207],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987384,0.0009407497,7.371734e-7,0.0001394004,0.00003657299,0.0001316683,0.000003825772,0.000004073089,0.000004588748],"genre_scores_gemma":[0.9991083,0.00009890483,0.0002717272,0.0002818647,0.00019563,0.000006816419,0.00001434632,0.00001794923,0.000004475122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9286886,"threshold_uncertainty_score":0.7934586,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2107944268","doi":"10.1139/o02-161","title":"TGF-β and the Smad signal transduction pathway","year":2002,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"R-SMAD; SMAD; Cell biology; Signal transduction; Biology; Transcription factor; Transforming growth factor beta; Transmembrane protein; Transforming growth factor; TGF beta signaling pathway; Cell surface receptor; Intracellular; Receptor; Endoglin; Genetics; Gene","authors":[{"name":"Arun Mehra","is_ca":true},{"name":"Jeffrey L. Wrana","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01614195581238684,"gpt":0.2467790544821025,"spread":0.2306370986697156,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000280816,0.0004747125,0.0007252223,0.000029501,0.0001762501,0.00003636616,0.0002855156,0.0008886317,0.0001087998],"category_scores_gemma":[0.00005060559,0.0003193186,0.0002908528,0.00006843585,0.0007840721,0.000001766508,0.0001395285,0.0002712763,0.000009865833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001094064,"about_ca_system_score_gemma":0.0001229703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000398788,"about_ca_topic_score_gemma":5.99371e-7,"domain_scores_codex":[0.9981467,0.0002852014,0.0004175778,0.0007703665,0.00006594803,0.0003142493],"domain_scores_gemma":[0.9990674,0.0001008926,0.0002344566,0.0004309332,0.00003506139,0.0001313177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001711876,0.0001249948,0.000008900713,0.007356315,0.0003039503,0.000007062927,0.00003851537,4.340277e-7,0.05749233,0.00004775728,0.001104156,0.9333444],"study_design_scores_gemma":[0.0006077063,0.00007956755,4.010149e-7,0.0002909449,0.0003106287,0.00008827718,0.00001727128,0.000002288675,0.0507393,0.00002286453,0.9474556,0.0003851318],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00238767,0.9957179,0.00004208417,0.000022351,0.0001234271,0.0003120054,0.0001303611,0.00001987561,0.001244323],"genre_scores_gemma":[0.008840417,0.9875233,0.00005035972,0.00006565129,0.000718159,0.0001123213,0.0008087746,0.00003872034,0.001842268],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9463515,"threshold_uncertainty_score":0.9999259,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2080754894","doi":"10.1002/jcb.10515","title":"Phenotype discovery by gene expression profiling: Mapping of biological processes linked to BMP‐2‐mediated osteoblast differentiation","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Genetics; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health","keywords":"RUNX2; Osteoblast; Bone morphogenetic protein 2; Biology; Bone morphogenetic protein; Cell biology; Phenotype; Gene expression profiling; SMAD; Cellular differentiation; Gene; Transcription factor; Signal transduction; Gene expression; C2C12; Genetics; In vitro","authors":[{"name":"Éva Bálint","is_ca":false},{"name":"David Lapointe","is_ca":false},{"name":"Hicham Drissi","is_ca":false},{"name":"Caroline van der Meijden","is_ca":false},{"name":"Daniel Young","is_ca":false},{"name":"André J. van Wijnen","is_ca":false},{"name":"Janet L. Stein","is_ca":false},{"name":"Gary S. Stein","is_ca":false},{"name":"Jane B. Lian","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01211180974874958,"gpt":0.2260588940356639,"spread":0.2139470842869143,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002474299,0.0002325762,0.0002999821,0.00006194972,0.00005814338,0.00004241036,0.0003087611,0.0002739169,0.0000230744],"category_scores_gemma":[0.001337252,0.0001915126,0.0001468451,0.0001843001,0.00007386001,0.000012678,0.00008018132,0.0001523781,0.00000246146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002665485,"about_ca_system_score_gemma":0.0003253842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.160643e-7,"about_ca_topic_score_gemma":8.4711e-8,"domain_scores_codex":[0.9983957,0.00008264387,0.0006593021,0.0003082788,0.0003094664,0.000244651],"domain_scores_gemma":[0.9984506,0.00003954709,0.0006324148,0.0002733081,0.0004154509,0.0001886778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002290687,0.0002928864,0.003368905,0.0002315049,0.00006615255,0.000005109236,0.00003655743,0.00004499331,0.9951856,0.000001074846,0.0004928763,0.00004534256],"study_design_scores_gemma":[0.0005986917,0.0002455794,0.0001683942,0.0001640469,0.00002858961,0.00001276664,0.0001317958,0.000002932545,0.9975342,0.00001621618,0.000876972,0.0002197919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761769,0.003914197,0.01950561,0.0000198141,0.0001202099,0.0001466356,0.00004778769,0.000008206104,0.00006071293],"genre_scores_gemma":[0.9957194,0.00007165478,0.003424854,0.00004060477,0.0002393642,0.000008424397,0.0003159556,0.00002681976,0.0001528746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01954261,"threshold_uncertainty_score":0.7809657,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2119505108","doi":"10.1091/mbc.e06-07-0602","title":"Cell Contact–dependent Regulation of Epithelial–Myofibroblast Transition via the Rho-Rho Kinase-Phospho-Myosin Pathway","year":2007,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":172,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"Myocardin; Myofibroblast; Cell biology; Biology; Serum response factor; Transdifferentiation; Myosin; Coactivator; Actin; Myosin light-chain kinase; Phosphorylation; Transcription factor; Fibrosis; Biochemistry; Stem cell; Internal medicine","authors":[{"name":"Lingzhi Fan","is_ca":true},{"name":"Attila Sebe","is_ca":true},{"name":"Zalán Péterfi","is_ca":true},{"name":"András Masszi","is_ca":true},{"name":"Ana C.P. Thirone","is_ca":true},{"name":"Ori D. Rotstein","is_ca":true},{"name":"Hiroyasu Nakano","is_ca":false},{"name":"Christopher A. McCulloch","is_ca":true},{"name":"Katalin Szászi","is_ca":true},{"name":"István Mucsi","is_ca":false},{"name":"András Kapùs","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003840864620141658,"gpt":0.2074921969670868,"spread":0.2036513323469451,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005624273,0.0002403493,0.0002406639,0.00005031444,0.0001117263,0.000007245349,0.0005442122,0.0003018626,0.00003283285],"category_scores_gemma":[0.00004288091,0.0001682138,0.0002983774,0.0001243533,0.0003244697,0.000003517247,0.000132218,0.0001374643,0.000007489817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002254054,"about_ca_system_score_gemma":0.00009250083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006686946,"about_ca_topic_score_gemma":0.00002192132,"domain_scores_codex":[0.9983345,0.0002878906,0.0004870672,0.000381998,0.0001908309,0.0003176934],"domain_scores_gemma":[0.9985679,0.00005177729,0.0003852021,0.0007804388,0.000148479,0.00006613636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002678603,0.0001920088,0.0003616738,0.00005456397,0.00005328498,0.00000233499,0.0001105743,0.0007100577,0.9975011,0.00007787181,0.0001112149,0.0005574203],"study_design_scores_gemma":[0.0007319363,0.0003340468,0.002601933,0.00003026153,0.00007250493,0.000006095287,0.00005927013,0.00004861674,0.9939317,0.0003702157,0.001627485,0.0001859277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9618062,0.002367428,0.03438838,0.0001348086,0.000235735,0.0004055412,0.00008105196,0.00001281053,0.0005679865],"genre_scores_gemma":[0.998708,0.0000204868,0.0005321542,0.0002540814,0.00007240575,0.00001079262,0.0001489143,0.00003420928,0.0002189331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03690176,"threshold_uncertainty_score":0.6859561,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}