{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":1121,"total_is_capped":false,"direct_labels_cover":2,"predictions_cover":1121,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"ccd2d4ff3e79","filters":{"topic":"Thyroid Disorders and Treatments"}},"results":[{"id":"W2124173888","doi":"10.1210/jc.2011-2803","title":"Management of Thyroid Dysfunction during Pregnancy and Postpartum: An Endocrine Society Clinical Practice Guideline","year":2012,"lang":"en","type":"review","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":1863,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"U.S. Food and Drug Administration","keywords":"Guideline; Medicine; Thyroid; Pregnancy; Endocrine system; Family medicine; Pediatrics; Gynecology; Obstetrics; Internal medicine; Pathology; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.09891133833274282,"gpt":0.4557273593187856,"spread":0.3568160209860428,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002965044,0.0006300669,0.00508041,0.0001647506,0.0001391941,0.00001520944,0.0005078979,0.0004351142,0.00007068998],"category_scores_gemma":[0.0008081628,0.0003560854,0.00214354,0.0002583192,0.0006284747,0.0003808239,0.0003931975,0.002283748,0.00002166201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003654491,"about_ca_system_score_gemma":0.0002908106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001737812,"about_ca_topic_score_gemma":0.000001447332,"domain_scores_codex":[0.9894016,0.00209854,0.006694426,0.0004766403,0.0006522844,0.0006765372],"domain_scores_gemma":[0.9905108,0.001688607,0.005645162,0.001022834,0.0006437903,0.0004888143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001236297,0.002720981,0.0003484881,0.002710167,0.008056735,0.0005787973,0.00006425158,4.667975e-7,0.000001214589,0.0005407888,0.0007252085,0.9830166],"study_design_scores_gemma":[0.008597975,0.001524516,0.005729261,0.003910424,0.04995452,0.0093721,0.0002741911,0.000001858123,0.000002709327,0.0001300642,0.9202451,0.0002573533],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002870284,0.9922389,0.00009271527,0.001255966,0.001896142,0.0009940383,0.000019456,0.00002704584,0.0006054277],"genre_scores_gemma":[0.0008307457,0.9875718,0.008650657,0.0003618893,0.002031242,0.00001706653,0.00003123417,0.00008243215,0.0004229468],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9827592,"threshold_uncertainty_score":0.9998891,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1747119434","doi":"10.1089/thy.2014.0028","title":"Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement","year":2014,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":1857,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network","funders":"National Center for Advancing Translational Sciences","keywords":"Task force; Thyroid; Medicine; Hormone; Hormone replacement; Task (project management); Internal medicine; Endocrinology; Engineering; Political science","retraction":null,"screen_n_in":null,"score":{"opus":0.02405625970207743,"gpt":0.3059367189588494,"spread":0.281880459256772,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000761581,0.0005536707,0.0008918006,0.00009804706,0.0004651443,0.00005448458,0.0003434044,0.0001161135,0.0000140052],"category_scores_gemma":[0.0007310198,0.0002943943,0.0005335083,0.0003627591,0.0002041667,0.00007774765,0.00004777277,0.0001426396,0.00005083138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005830632,"about_ca_system_score_gemma":0.00009760998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005499762,"about_ca_topic_score_gemma":0.00007468593,"domain_scores_codex":[0.9967318,0.0001827802,0.0008835975,0.0006728127,0.0008357581,0.0006932234],"domain_scores_gemma":[0.9957328,0.001214949,0.0009969757,0.001398852,0.0004825779,0.0001737876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008697509,0.003580031,0.003816307,0.00003022692,0.002246635,0.000003105085,0.002034392,0.0002119597,0.1084848,0.0006791041,0.8297591,0.04045679],"study_design_scores_gemma":[0.06531759,0.1284113,0.03664412,0.0001261274,0.005604744,0.00006229147,0.004926132,0.01267891,0.08765527,0.003044114,0.6536868,0.001842655],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9381977,0.02175961,0.002942601,0.02635997,0.0003663567,0.005447726,0.0004935269,0.0002384096,0.004194106],"genre_scores_gemma":[0.9710943,0.005959433,0.0008144117,0.003119602,0.0005104601,0.00107316,0.0003279329,0.0001138916,0.01698679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1760723,"threshold_uncertainty_score":0.9999508,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2052693888","doi":"10.1111/j.1365-2826.2004.01243.x","title":"Timing of Thyroid Hormone Action in the Developing Brain: Clinical Observations and Experimental Findings","year":2004,"lang":"en","type":"review","venue":"Journal of Neuroendocrinology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":596,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Institutes of Health; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; March of Dimes Foundation","keywords":"Neuropsychology; Offspring; Pregnancy; Thyroid; Psychology; Hormone; Developmental psychology; Action (physics); Congenital hypothyroidism; Endocrinology; Neuroscience; Medicine; Internal medicine; Physiology; Cognition; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.2556455228386608,"gpt":0.4521336632795108,"spread":0.1964881404408501,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012082,0.0002037775,0.001249821,0.0003092762,0.00004771176,0.00001017854,0.0001463638,0.00009106172,0.00000369984],"category_scores_gemma":[0.000310079,0.0001282291,0.0003194457,0.0002089357,0.0001109854,0.00008492391,0.00005483449,0.0006821039,0.000001266659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001288774,"about_ca_system_score_gemma":0.000439629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009517148,"about_ca_topic_score_gemma":0.000003230705,"domain_scores_codex":[0.9980481,0.0002134104,0.00115375,0.0001717451,0.0002136582,0.0001993096],"domain_scores_gemma":[0.9985657,0.000443068,0.0007158426,0.0001511215,0.00007513489,0.00004914002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001026372,0.004357177,0.00747292,0.009111621,0.002238751,0.01240024,0.001554359,0.000005671579,0.0005155811,0.002406796,0.008484588,0.9504259],"study_design_scores_gemma":[0.01227404,0.007907179,0.06734454,0.009216877,0.00223348,0.05691954,0.0009999834,0.000002873586,0.00005435525,0.0002742689,0.8423684,0.0004044211],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08292796,0.9146554,0.00001073703,0.001831868,0.0002136617,0.0003190537,0.000003646727,0.000003985436,0.00003362805],"genre_scores_gemma":[0.01459517,0.984502,0.0004263032,0.0003337821,0.000089742,0.000008896299,0.000005750937,0.00002052346,0.00001781712],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9500215,"threshold_uncertainty_score":0.522903,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2096524107","doi":"10.1001/archinte.160.11.1573","title":"American Thyroid Association Guidelines for Detection of Thyroid Dysfunction","year":2000,"lang":"en","type":"article","venue":"Archives of Internal Medicine","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":588,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"","keywords":"Thyroid dysfunction; Medicine; Thyroid; Association (psychology); Internal medicine; Psychology","retraction":null,"screen_n_in":null,"score":{"opus":0.01711328047045975,"gpt":0.3070943796543622,"spread":0.2899810991839025,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001390434,0.0001344101,0.0004378223,0.0001699397,0.00003005479,0.00000174081,0.00007158603,0.00003110295,0.00009836475],"category_scores_gemma":[0.0006491065,0.00009689767,0.0001521687,0.0001266596,0.000150029,0.00004340149,0.00001059608,0.00008274158,0.000004956789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003972138,"about_ca_system_score_gemma":0.00002311698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001485814,"about_ca_topic_score_gemma":0.00008031828,"domain_scores_codex":[0.9988146,0.00002980877,0.0005461911,0.0001809912,0.0002685743,0.0001598423],"domain_scores_gemma":[0.998915,0.0002656144,0.000379096,0.0001701074,0.0001946812,0.00007548612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.004101275,0.0002958147,0.02811957,0.00009090199,0.0004584547,0.000002916108,0.0006943351,0.00001850798,0.355632,0.00005045737,0.002490156,0.6080456],"study_design_scores_gemma":[0.03502108,0.04395558,0.5835962,0.002117582,0.001737757,0.0001152344,0.002542973,0.005569055,0.2926477,0.005575593,0.02663957,0.0004816513],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792343,0.001100105,0.007479146,0.002774877,0.0001996606,0.0004174528,0.00002244102,0.00003218868,0.008739851],"genre_scores_gemma":[0.9931699,0.0006637159,0.001710069,0.000453579,0.000296555,0.00002392556,0.00002962427,0.00001809702,0.003634507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.607564,"threshold_uncertainty_score":0.3951372,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144142907","doi":"10.1210/jc.2013-1891","title":"European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism","year":2014,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":565,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Universitas Padjadjaran; Università di Pisa; Università di Bologna; Christian Medical College, Vellore; University of Toronto; Newcastle University; Universiteit van Amsterdam; Universität Basel; Radboud Universiteit; University of Pittsburgh","keywords":"Congenital hypothyroidism; Medicine; Pediatrics; Newborn screening; Pediatric endocrinology; Guideline; Family medicine; Grading (engineering); MEDLINE; Quality of evidence; Intensive care medicine; Randomized controlled trial; Thyroid; Internal medicine; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.09362674467231519,"gpt":0.38569639279996,"spread":0.2920696481276448,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001563408,0.0002599693,0.001144159,0.0001140955,0.0001138281,0.00000738966,0.0002720715,0.00009378628,0.00001471981],"category_scores_gemma":[0.001095111,0.000157515,0.0007911372,0.0001049076,0.0006006492,0.00003134612,0.0001466269,0.0004583723,0.000008205871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006915036,"about_ca_system_score_gemma":0.00004166739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001291543,"about_ca_topic_score_gemma":0.000002345964,"domain_scores_codex":[0.9967074,0.0005276706,0.001791373,0.0002551206,0.0002700908,0.0004482839],"domain_scores_gemma":[0.9958969,0.00204017,0.001070286,0.0003833641,0.000419846,0.0001894354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.008352512,0.00327675,0.08390755,0.0002485354,0.01363518,0.0004780951,0.000335033,0.0001111139,0.0003945674,0.03077454,0.08836025,0.7701259],"study_design_scores_gemma":[0.04255605,0.005242918,0.5952434,0.0001148535,0.008813821,0.001463727,0.0006496468,0.0001375369,0.0008167544,0.002964836,0.341669,0.0003275046],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9546469,0.03003813,0.000817426,0.01219012,0.0006915877,0.0005726762,0.00002230714,0.00002224086,0.000998618],"genre_scores_gemma":[0.924659,0.05782547,0.01308236,0.002982809,0.001100706,0.00001553357,0.000004672566,0.00004217844,0.0002872804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7697983,"threshold_uncertainty_score":0.6423275,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2117317136","doi":"10.1210/edrv.22.2.0427","title":"The Effects of Amiodarone on the Thyroid*","year":2001,"lang":"en","type":"review","venue":"Endocrine Reviews","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":487,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Amiodarone; Medicine; Thyroid; Thyroiditis; Internal medicine; Endocrinology; Iodothyronine deiodinase; Thyroid function tests; Anti-thyroid autoantibodies; Wolff–Chaikoff effect; Thyroid function; Hormone; Gastroenterology; Deiodinase; Autoantibody; Immunology; Triiodothyronine; Atrial fibrillation; Antibody","retraction":null,"screen_n_in":null,"score":{"opus":0.04366476531443681,"gpt":0.3591307418720594,"spread":0.3154659765576226,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003884324,0.0005979722,0.002912229,0.00007827971,0.0001712878,0.00002065407,0.0003950823,0.0000760581,0.00007923044],"category_scores_gemma":[0.001101958,0.0002141167,0.001439918,0.0005081295,0.0001284405,0.00001857371,0.00009857273,0.000518603,0.0008036397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008617259,"about_ca_system_score_gemma":0.0001075574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002453502,"about_ca_topic_score_gemma":0.000006538692,"domain_scores_codex":[0.9972804,0.0005788537,0.001013657,0.0003780929,0.0003315404,0.0004175105],"domain_scores_gemma":[0.996085,0.001528521,0.0007157522,0.001528554,0.00003775876,0.000104409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001038264,0.0001930419,0.000002934838,0.01482979,0.0003049684,0.00007615094,0.000007934314,3.859278e-9,3.510075e-7,0.0009881259,0.03395293,0.9496334],"study_design_scores_gemma":[0.0005398921,0.0005288491,0.00000700789,0.02402335,0.002358532,0.0001713117,0.000004527562,8.741956e-8,0.000004155515,0.00006202532,0.9721431,0.0001571681],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003039129,0.9808917,0.000002223097,0.0004627489,0.0003296953,0.005424092,0.000008781063,0.00002723817,0.0128505],"genre_scores_gemma":[0.000003519449,0.9870159,0.00002740884,0.0002229049,0.0002476766,0.0009761055,0.00005129335,0.00006879134,0.01138641],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9494762,"threshold_uncertainty_score":0.9999744,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3108540964","doi":"10.1089/thy.2020.0333","title":"Congenital Hypothyroidism: A 2020–2021 Consensus Guidelines Update—An ENDO-European Reference Network Initiative Endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology","year":2020,"lang":"en","type":"review","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":446,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Newborn Screening Ontario","funders":"Medical Research Council","keywords":"Pediatric endocrinology; Congenital hypothyroidism; Levothyroxine; Medicine; Newborn screening; Pediatrics; Family medicine; Guideline; Grading (engineering); MEDLINE; Harmonization; Expert opinion; Quality of evidence; Intensive care medicine; Thyroid; Internal medicine; Randomized controlled trial; Pathology; Political science","retraction":null,"screen_n_in":null,"score":{"opus":0.0751705707744276,"gpt":0.3270732993274015,"spread":0.2519027285529739,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001919174,0.001517162,0.003038076,0.00006636326,0.001107427,0.0001775971,0.001109404,0.0002378759,0.00003399201],"category_scores_gemma":[0.0008384772,0.0009062074,0.002710252,0.0005038661,0.001281651,0.0000947079,0.0008482844,0.001345469,0.0001829918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001254115,"about_ca_system_score_gemma":0.0004685853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003700049,"about_ca_topic_score_gemma":0.00001963762,"domain_scores_codex":[0.990508,0.003643042,0.001985872,0.001809008,0.0003892075,0.001664836],"domain_scores_gemma":[0.9937044,0.002709839,0.001361671,0.001279823,0.0005105273,0.0004337586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006028033,0.0003583235,0.00003363636,0.001543418,0.00601922,0.000518699,0.001229431,0.000002545114,0.00002790645,0.001335207,0.5641096,0.4242193],"study_design_scores_gemma":[0.0151938,0.001157519,0.00004337667,0.0001959225,0.01062859,0.001426328,0.001030257,0.00006440431,0.000002513745,0.000304118,0.969139,0.0008141379],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001806247,0.9752638,0.0004390648,0.003876848,0.0005210967,0.006830471,0.003148304,0.000248974,0.009490835],"genre_scores_gemma":[0.001929599,0.9816062,0.002723658,0.003315232,0.004472059,0.0006715198,0.003977996,0.0004832194,0.0008204877],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4234051,"threshold_uncertainty_score":0.9997577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1972291506","doi":"10.1089/thy.2013.0128","title":"Global Iodine Nutrition: Where Do We Stand in 2013?","year":2013,"lang":"en","type":"review","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":443,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Iodised salt; Iodine deficiency; Iodine; Medicine; Environmental health; Goiter; Population; Developing country; Pregnancy; Thyroid; Pediatrics; Endocrinology; Economic growth; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.03474539047596092,"gpt":0.3364982140636256,"spread":0.3017528235876646,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008056174,0.0005488654,0.001928786,0.0001625437,0.00004576066,0.00005046683,0.0001753216,0.0004035905,0.0008960037],"category_scores_gemma":[0.00001412337,0.0004024516,0.0004180344,0.0005153249,0.00006423607,0.0000884792,0.00007649563,0.0002988038,0.001683021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004313735,"about_ca_system_score_gemma":0.0002826618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001543378,"about_ca_topic_score_gemma":0.0001039061,"domain_scores_codex":[0.9980494,0.00007863399,0.0005969342,0.0005226482,0.0003108661,0.0004414518],"domain_scores_gemma":[0.9988894,0.00003832914,0.0001998189,0.0005869605,0.00006117366,0.0002242813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004222045,0.0008942927,0.000109305,0.01649482,0.0002263625,0.0002788024,0.00002105283,6.142569e-8,1.810309e-7,0.0001786583,0.1921818,0.7895724],"study_design_scores_gemma":[0.003603843,0.000327266,0.0000315758,0.02217838,0.0006933508,0.0002064184,0.00004326185,6.277317e-7,1.158705e-7,0.0004393472,0.9721666,0.0003091879],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003387304,0.9898577,0.000003637205,0.0006140709,0.0001945864,0.002229487,0.0002681799,0.0000733202,0.006725129],"genre_scores_gemma":[0.00001781575,0.9953229,0.0002975049,0.00001976659,0.0002795414,0.000405823,0.0001685204,0.00005456507,0.003433512],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7892632,"threshold_uncertainty_score":0.9998428,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1651572921","doi":"10.1001/jama.2015.5161","title":"Subclinical Thyroid Dysfunction and Fracture Risk","year":2015,"lang":"en","type":"review","venue":"JAMA","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":333,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Norwegian Institute of Public Health; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Alexion Pharmaceuticals; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Commission; Fonterra Co-Operative Group; National Osteoporosis Society; National Institute on Aging; National Institute for Health and Care Research; National Institute of Nursing Research; International Osteoporosis Foundation; Cancer Research UK; Amgen; Radius Health; Schweizerische Herzstiftung; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Norges Teknisk-Naturvitenskapelige Universitet; GlaxoSmithKline; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb; National Institute of Neurological Disorders and Stroke; University of Pittsburgh; Pfizer; ZonMw; Alere; American Heart Association; National Science Foundation","keywords":"Subclinical infection; Medicine; Prospective cohort study; Thyroid; Thyroid function; Hazard ratio; Cohort study; Internal medicine; Thyroid function tests; Pediatrics; Surgery; Confidence interval","retraction":null,"screen_n_in":null,"score":{"opus":0.04314738198995324,"gpt":0.3592069520200826,"spread":0.3160595700301294,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002204282,0.0003002324,0.001313885,0.00008101221,0.00004838868,0.00003353163,0.00005141935,0.000598686,0.00005460255],"category_scores_gemma":[0.0002507541,0.000186466,0.000290817,0.0001111328,0.00004486261,0.00005170629,0.00004272573,0.0006459797,0.0003140816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007247017,"about_ca_system_score_gemma":0.0001943737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004101967,"about_ca_topic_score_gemma":0.000004408432,"domain_scores_codex":[0.9987965,0.00009914302,0.0003461122,0.0003703045,0.0002152297,0.0001727174],"domain_scores_gemma":[0.9989709,0.0001235485,0.0002488071,0.0003598963,0.000069384,0.0002275115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004784674,0.0001311085,0.0003504414,0.001275941,0.0002526452,0.00005298578,0.00001514776,2.282488e-8,7.396043e-9,0.000008001482,0.04646319,0.9514027],"study_design_scores_gemma":[0.002570946,0.0004412164,0.0004837955,0.001414914,0.003166977,0.0001367672,0.00001253755,0.000001425575,3.012573e-8,0.0001711631,0.9914493,0.0001509441],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007079728,0.9948286,0.00001545242,0.0001982801,0.0002162385,0.0006005843,0.00005579545,0.00005411147,0.003960175],"genre_scores_gemma":[0.00006040758,0.9967141,0.0001121909,0.0003640606,0.000583208,0.00003892785,0.000383819,0.00004663451,0.001696622],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9512517,"threshold_uncertainty_score":0.7603864,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2922677918","doi":"10.1111/nyas.14041","title":"Excess iodine intake: sources, assessment, and effects on thyroid function","year":2019,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":324,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Stem Cell Network","funders":"World Health Organization","keywords":"Iodine; Thyroid function; Thyroid; Endocrinology; Population; Goiter; Iodine deficiency; Internal medicine; Medicine; Physiology; Chemistry; Environmental health","retraction":null,"screen_n_in":null,"score":{"opus":0.05033399204357641,"gpt":0.3438516425927489,"spread":0.2935176505491724,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003501046,0.0001160715,0.0002574138,0.0000954359,0.00009748896,0.0000139954,0.0002019006,0.00007367822,0.00002514262],"category_scores_gemma":[0.00003026205,0.00006544271,0.00008223022,0.0003418013,0.0002530874,0.0001082873,0.00006226429,0.0001421593,0.000008864902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005812617,"about_ca_system_score_gemma":0.00005692255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007156863,"about_ca_topic_score_gemma":0.000001217095,"domain_scores_codex":[0.9989184,0.0000417203,0.0001858489,0.0002381493,0.0004383728,0.0001775441],"domain_scores_gemma":[0.9994679,0.0001228666,0.0002138699,0.00009667069,0.00001741211,0.00008128853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007410964,0.000542968,0.7600894,0.0003576408,0.000316201,6.871423e-7,0.000624603,0.0001325907,0.07255413,0.009829782,0.04810438,0.1067065],"study_design_scores_gemma":[0.002148625,0.002584846,0.8941365,0.0004302792,0.00009879259,0.000006106717,0.000236806,0.00009863979,0.08818267,0.008004933,0.003952269,0.0001194834],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806393,0.003301357,0.000005934497,0.01211086,0.0001067752,0.0003313059,0.000002516293,0.00001158515,0.003490308],"genre_scores_gemma":[0.9961079,0.0002726298,0.000102815,0.002267819,0.00005788669,0.000002684292,6.598044e-7,0.000005325563,0.001182251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1340472,"threshold_uncertainty_score":0.2668676,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2896468934","doi":"10.1038/s41467-018-06356-1","title":"Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation","year":2018,"lang":"en","type":"review","venue":"Nature Communications","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":289,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Jewish General Hospital","funders":"National Heart, Lung, and Blood Institute; Steno Diabetes Center Copenhagen; Medical Research Council; National Institute for Health and Care Research; Biotechnology and Biological Sciences Research Council; Novo Nordisk Fonden","keywords":"Computational biology; Thyroid; Genome; Hormone; Bioinformatics; Biology; Medicine; Genetics; Endocrinology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.07822393935250292,"gpt":0.4297350484913113,"spread":0.3515111091388084,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002133071,0.0003016517,0.001007441,0.0004169831,0.0002043372,0.00004596809,0.0004612573,0.0006320056,0.000006999901],"category_scores_gemma":[0.00029698,0.0002432553,0.0002931363,0.0005275339,0.000133865,0.00009670258,0.0002643807,0.0005465903,0.00001903051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001593261,"about_ca_system_score_gemma":0.0001610534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003669467,"about_ca_topic_score_gemma":0.0005796785,"domain_scores_codex":[0.9986424,0.0001324663,0.0005151511,0.0003541334,0.0001517464,0.0002041228],"domain_scores_gemma":[0.9970349,0.0004308777,0.0003040806,0.001981252,0.0001598563,0.0000890269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003699764,0.004293157,0.006196954,0.01161401,0.006166732,0.0000199553,0.001529705,0.000001445625,0.0003090136,0.003490656,0.03925063,0.9267578],"study_design_scores_gemma":[0.0009699233,0.0001182307,0.0167565,0.001187592,0.001965106,0.00001963746,0.00004687008,0.00002188436,0.000001052564,0.0005485134,0.9781594,0.0002053222],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002009869,0.9962362,0.00002915286,0.0004255346,0.0000380517,0.00183954,0.0001364561,0.00004053908,0.001053534],"genre_scores_gemma":[0.01066242,0.980334,0.003438876,0.00008836248,0.00006502463,0.0004662065,0.004421334,0.00005255645,0.0004711575],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9389088,"threshold_uncertainty_score":0.9919664,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1992227666","doi":"10.1089/thy.2006.16.949","title":"Iodine Supplementation for Pregnancy and Lactation—United States and Canada: Recommendations of the American Thyroid Association","year":2006,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":246,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Pregnancy; Medicine; Thyroid function; Fetus; Lactation; Iodine deficiency; Thyroid; Iodine; Endocrinology; Gestation; Physiology; Internal medicine; Hormone; Obstetrics; Biology; Chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.007637973648382667,"gpt":0.2543523689903729,"spread":0.2467143953419903,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005672292,0.00008629078,0.0001517418,0.0000540114,0.0001218813,0.00001167847,0.00002515154,0.0000169813,0.000005741646],"category_scores_gemma":[0.00005051259,0.00006521329,0.0000238554,0.0001537829,0.00003666645,0.00004972292,0.00001452266,0.00003837631,2.227638e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000126111,"about_ca_system_score_gemma":0.00008148752,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.262946,"about_ca_topic_score_gemma":0.302704,"domain_scores_codex":[0.9993924,0.00003044167,0.0001944877,0.0001207503,0.0001349924,0.0001269282],"domain_scores_gemma":[0.9993775,0.0001400132,0.0002477251,0.00009180812,0.0001109067,0.00003206306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002608663,0.0003781324,0.8598126,0.00009828778,0.0002408523,0.000001260816,0.0006153737,0.00003294774,0.007567931,0.001446554,0.1219784,0.007566794],"study_design_scores_gemma":[0.006565392,0.0006297224,0.9751132,0.00007969416,0.000339997,0.000004730415,0.00163371,0.0006079373,0.005570673,0.001658517,0.007641984,0.0001545094],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875633,0.0005232911,0.00009405179,0.01048441,0.00003890813,0.0005957554,0.0004470965,0.00001318036,0.0002400444],"genre_scores_gemma":[0.9956933,0.0005305057,0.0008492318,0.0003039911,0.00002159882,0.0000593805,0.001224179,0.00001178787,0.001306003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1153006,"threshold_uncertainty_score":0.7419621,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2765818361","doi":"10.1161/circulationaha.117.028753","title":"Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation","year":2017,"lang":"en","type":"review","venue":"Circulation","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":246,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Institute for Health and Care Research; National Institute of Nursing Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Medical Research Council; National Institute on Aging; Schweizerische Herzstiftung; National Heart, Lung, and Blood Institute; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Commission; National Center for Advancing Translational Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Cancer Research UK","keywords":"Medicine; Subclinical infection; Atrial fibrillation; Cardiology; Internal medicine; Thyroid; Thyroid function; Thyroid function tests","retraction":null,"screen_n_in":null,"score":{"opus":0.06520820878022651,"gpt":0.3401438202923369,"spread":0.2749356115121104,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001074665,0.0002799358,0.001155324,0.00008030526,0.000385264,0.00005466135,0.0001107571,0.0003162035,0.00001010771],"category_scores_gemma":[0.0007979008,0.0001351279,0.0008829226,0.0001187056,0.0003238195,0.0001078853,0.00004951469,0.0003357401,0.00002271105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004561278,"about_ca_system_score_gemma":0.0001762972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001093858,"about_ca_topic_score_gemma":0.00002215185,"domain_scores_codex":[0.9979769,0.0004545678,0.0007805402,0.0003184645,0.0003318969,0.0001376535],"domain_scores_gemma":[0.9968922,0.0007039896,0.001538811,0.0007170594,0.00009338855,0.00005454915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001120732,0.00003079654,0.02392611,0.001247573,0.001342911,0.000002476266,0.0002074386,0.0000863833,4.541346e-7,0.00127942,0.000133648,0.9706221],"study_design_scores_gemma":[0.0352936,0.000746511,0.3589977,0.004509245,0.05939994,0.0002975358,0.0001299759,0.003023263,7.274549e-7,0.006099274,0.5306279,0.0008743777],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005693967,0.9909288,0.0001611004,0.00008636741,0.0004967705,0.001989687,0.00003296126,0.00002470756,0.0005856132],"genre_scores_gemma":[0.1303634,0.8684077,0.00001987357,0.00001135427,0.0008570028,0.00002016876,0.0002046232,0.00003274332,0.00008324038],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9697477,"threshold_uncertainty_score":0.5510358,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2158533218","doi":"10.1542/peds.2005-0227","title":"Neonatal Effects of Maternal Hypothyroxinemia During Early Pregnancy","year":2006,"lang":"en","type":"article","venue":"PEDIATRICS","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Medicine; Gestation; Thyroid function; Pregnancy; Percentile; Obstetrics; Thyroid; Thyroid function tests; Pediatrics; Endocrinology","retraction":null,"screen_n_in":null,"score":{"opus":0.002756334633725709,"gpt":0.1977341138657235,"spread":0.1949777792319978,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001398229,0.0001177508,0.0001868604,0.0001023717,0.00003231493,0.000007759284,0.00005115075,0.00006247011,0.00001556543],"category_scores_gemma":[0.00002626526,0.0001013728,0.00008190901,0.0001623208,0.00002003504,0.00005308429,0.00002972833,0.00007427275,0.0000359511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002814507,"about_ca_system_score_gemma":0.00002941176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000256035,"about_ca_topic_score_gemma":0.000005625397,"domain_scores_codex":[0.9992346,0.000008020394,0.0001857465,0.0001523314,0.0002203553,0.0001990098],"domain_scores_gemma":[0.9996167,0.0000355563,0.00008332403,0.0001626486,0.00003971834,0.00006204515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006761274,0.000199329,0.9940072,0.0004992834,0.00001867729,0.0003252206,0.00005313173,0.000003876293,0.002827902,0.00008080873,0.0001506904,0.001766283],"study_design_scores_gemma":[0.003345337,0.0001817523,0.9788141,0.00005296885,0.0001658078,0.00002885633,0.000003529332,0.000004544352,0.01708035,0.0002035151,0.00003754913,0.00008171294],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989654,0.008643208,0.00005746228,0.00002095561,0.0001525278,0.000241779,0.00001078395,0.00004803306,0.001171275],"genre_scores_gemma":[0.9974169,0.0002414855,0.0004263626,0.000006515553,0.0002387414,0.00001263141,0.00001232011,0.00002144708,0.00162364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01519311,"threshold_uncertainty_score":0.4133864,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2161021796","doi":"10.1210/jc.2011-1073","title":"Is the Incidence of Congenital Hypothyroidism Really Increasing? A 20-Year Retrospective Population-Based Study in Québec","year":2011,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":233,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Centre hospitalier de l'Université Laval; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"CHU Sainte-Justine Foundation; Centre hospitalier universitaire Sainte-Justine; Canadian Child Health Clinician Scientist Program","keywords":"Etiology; Incidence (geometry); Medicine; Goiter; Congenital hypothyroidism; Population; Thyroid; Pediatrics; Retrospective cohort study; Dysgenesis; Gastroenterology; Internal medicine; Anatomy; Physics","retraction":null,"screen_n_in":null,"score":{"opus":0.05107400494089474,"gpt":0.3541067253655246,"spread":0.3030327204246299,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001884822,0.000194472,0.001067534,0.0001660125,0.00008424755,0.000005219,0.000412098,0.0001006522,0.00007542822],"category_scores_gemma":[0.002407857,0.00009978293,0.0003504548,0.0002529172,0.0003616208,0.0000922206,0.0000792191,0.0008610314,0.00001941968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000484787,"about_ca_system_score_gemma":0.0005196447,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03359549,"about_ca_topic_score_gemma":0.007823915,"domain_scores_codex":[0.9962844,0.001158206,0.001643746,0.0001928657,0.000432817,0.0002879279],"domain_scores_gemma":[0.9965621,0.001325728,0.001120258,0.0005135795,0.0003636104,0.0001146931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003993006,0.001786975,0.990806,0.000002641686,0.0005303116,0.0001263444,0.001562754,0.000003041841,0.00006788725,0.0002536202,0.0001038414,0.0007636162],"study_design_scores_gemma":[0.008603533,0.001566564,0.9854745,0.00002212546,0.001031466,0.0001668595,0.001210708,0.00001087569,0.0001137021,0.001637194,0.00008596646,0.00007647413],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993636,0.002754854,0.00001137388,0.002248731,0.0002721577,0.0004972859,0.000008300078,0.000009014584,0.0005623538],"genre_scores_gemma":[0.99826,0.0003145215,0.0003508137,0.0007925151,0.0001734115,0.000006398969,9.850925e-7,0.00001942008,0.00008195256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02577157,"threshold_uncertainty_score":0.9728399,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2097650598","doi":"10.1371/journal.pgen.1003266","title":"A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function","year":2013,"lang":"en","type":"review","venue":"PLoS Genetics","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":230,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland; McGill University; Jewish General Hospital","funders":"National Institute on Aging; Medical Research Council; Canadian Institutes of Health Research; Geriatric Research Education and Clinical Center; National Institutes of Health; National Heart, Lung, and Blood Institute; Ministero della Salute; Erasmus Medisch Centrum; National Institute on Minority Health and Health Disparities; National Center for Research Resources; Radboud Universiteit; National Institute of Diabetes and Digestive and Kidney Diseases; Biotechnology and Biological Sciences Research Council; ZonMw; Johns Hopkins University; European Commission; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; NIH Clinical Center; Provincia autonoma di Bolzano - Alto Adige; National Center for Advancing Translational Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust","keywords":"Biology; Thyroid; Endocrinology; Internal medicine; Hypothalamic–pituitary–thyroid axis; Euthyroid; Thyroid function; Endocrine system; Hormone; Medicine; Triiodothyronine","retraction":null,"screen_n_in":null,"score":{"opus":0.246904504344327,"gpt":0.3214015852191857,"spread":0.07449708087485868,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000255161,0.0004058021,0.003374084,0.0005401453,0.00003678934,0.00001835398,0.0001626246,0.0003224421,0.0001508268],"category_scores_gemma":[0.00002780141,0.0002258999,0.00108869,0.001142757,0.000114868,0.00003124923,0.0000366956,0.0002126165,0.000005239585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003233923,"about_ca_system_score_gemma":0.00005964046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001296329,"about_ca_topic_score_gemma":0.00001661898,"domain_scores_codex":[0.9974267,0.0002447313,0.001171949,0.0004315406,0.0005293699,0.0001956522],"domain_scores_gemma":[0.9981461,0.0002525516,0.0008671023,0.0005256938,0.0001486118,0.00005999334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0001398772,0.005780137,0.002631104,0.01756432,0.7723642,0.00000906659,0.005307513,0.00007528657,0.004167308,0.001535378,0.0009632302,0.1894626],"study_design_scores_gemma":[0.001451241,0.0007304562,0.02898158,0.0003444141,0.9623529,0.00001390616,0.00023074,0.0003408799,0.00003027365,0.0008048939,0.004341552,0.0003771989],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0199173,0.9780309,0.00005917228,0.0000299643,0.00001883419,0.001536959,0.0001422871,0.000009566129,0.0002550074],"genre_scores_gemma":[0.1363952,0.8626484,0.0002585046,0.00001578019,0.0000175723,0.0001214407,0.0003192504,0.00003089539,0.0001929751],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1899887,"threshold_uncertainty_score":0.9211929,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2945825315","doi":"10.1136/bmj.l2006","title":"Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline","year":2019,"lang":"en","type":"article","venue":"BMJ","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":230,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; Impact","funders":"","keywords":"Medicine; Guideline; Subclinical infection; Hormone; Thyroid; Quality of life (healthcare); Internal medicine; Pediatrics; Endocrinology; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.06696142142583308,"gpt":0.4419864920078653,"spread":0.3750250705820323,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008147536,0.0002783253,0.0007192582,0.00006182012,0.00006848011,0.00002541615,0.0001004379,0.0002179173,0.0001128044],"category_scores_gemma":[0.001476465,0.0001976887,0.0005504958,0.0001149526,0.00006016684,0.0001318211,0.00003973858,0.0001368371,0.0009940313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009270667,"about_ca_system_score_gemma":0.0002868554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007342293,"about_ca_topic_score_gemma":0.00001242001,"domain_scores_codex":[0.9974436,0.00009614503,0.001185969,0.0005788908,0.0003052848,0.0003900821],"domain_scores_gemma":[0.9973164,0.001084047,0.0003121217,0.0007468881,0.0002655127,0.0002750082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01199863,0.009249992,0.08087846,0.00004201582,0.001667723,0.0002633549,0.0001880817,0.000009746146,0.0009399746,0.001560899,0.8321381,0.06106308],"study_design_scores_gemma":[0.02613616,0.01180426,0.02187646,0.00002624603,0.0009252806,0.0001958715,0.0004024685,0.0004833446,0.0001707649,0.0004544879,0.9372292,0.0002954846],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8134652,0.008813482,0.001522117,0.1168745,0.00168588,0.009576485,0.0001111053,0.0003468356,0.04760434],"genre_scores_gemma":[0.8335123,0.001978442,0.1166442,0.01667979,0.002511188,0.0006806267,0.0005326438,0.0001541333,0.02730672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1151221,"threshold_uncertainty_score":0.9997838,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2789751709","doi":"10.1089/thy.2017.0681","title":"An Online Survey of Hypothyroid Patients Demonstrates Prominent Dissatisfaction","year":2018,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":229,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Medicine; Levothyroxine; Interquartile range; Quality of life (healthcare); Depression (economics); Computer-assisted web interviewing; Patient satisfaction; Internal medicine; Pediatrics; Family medicine; Thyroid; Surgery","retraction":null,"screen_n_in":null,"score":{"opus":0.04434371723863416,"gpt":0.3086823537976346,"spread":0.2643386365590004,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001244362,0.0001859272,0.0003147305,0.00009746951,0.00007345351,0.00001072658,0.00008437045,0.00008136841,0.00009413069],"category_scores_gemma":[0.00009944887,0.0001485268,0.00005710827,0.0002300376,0.0001631154,0.0001356311,0.00002268512,0.00008427954,0.00006156834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004710638,"about_ca_system_score_gemma":0.00007215521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363821,"about_ca_topic_score_gemma":0.001179767,"domain_scores_codex":[0.9987932,0.00007580545,0.0003335948,0.0002878725,0.0002709152,0.0002385909],"domain_scores_gemma":[0.9988871,0.00003700615,0.0001476904,0.0003965367,0.0003629856,0.0001686866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005719371,0.001829942,0.9643292,0.00001508595,0.00007746714,0.000002737486,0.0001441875,4.506754e-7,0.02160615,0.00001597328,0.0007746313,0.01063217],"study_design_scores_gemma":[0.003013124,0.003947422,0.9791662,0.00002219372,0.00007744099,0.000005060244,0.00006272215,0.0001431648,0.01329514,0.00008450895,0.00005447061,0.0001285564],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980074,0.0002260709,0.00005528365,0.00005741616,0.0001386889,0.000444247,0.0002321229,0.00006243666,0.0007762946],"genre_scores_gemma":[0.9976576,0.00004438659,0.0009933729,0.00006661198,0.00007786324,0.000009723854,0.0009555157,0.00003050178,0.0001644341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01483694,"threshold_uncertainty_score":0.6056745,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3096099429","doi":"10.3389/fendo.2020.596585","title":"The Role of the Thyroid Axis in Fish","year":2020,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":226,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fish <Actinopterygii>; Thyroid; Biology; Hypothalamic–pituitary–thyroid axis; Medicine; Internal medicine; Endocrinology; Computational biology; Bioinformatics; Fishery; Thyroid hormones","retraction":null,"screen_n_in":null,"score":{"opus":0.01218122225917746,"gpt":0.2740965791139368,"spread":0.2619153568547594,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005739024,0.0002865541,0.001510345,0.0001605586,0.00004739305,0.000005542374,0.0004508847,0.0001883405,0.00000915576],"category_scores_gemma":[0.0001534884,0.0001511716,0.0003872384,0.0004532992,0.0002486218,0.0000169441,0.0001932411,0.0006591607,0.00001142212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779729,"about_ca_system_score_gemma":0.0002568768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001065097,"about_ca_topic_score_gemma":0.0002175027,"domain_scores_codex":[0.9982572,0.0002417302,0.0005726612,0.0003383377,0.0001458552,0.0004442358],"domain_scores_gemma":[0.9990235,0.0001037732,0.0002345598,0.000575765,0.00001667331,0.00004572955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004015166,0.0001145892,0.0139963,0.0004961556,0.0002352972,0.0001061749,0.00008917721,2.170896e-7,1.916408e-7,0.0004477747,0.006012836,0.9784611],"study_design_scores_gemma":[0.0009378239,0.0001182802,0.001096033,0.0007340091,0.0002794624,0.00007774925,0.0002765583,0.000004196643,0.000003839522,0.001200381,0.9951679,0.0001037976],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006902344,0.9930329,0.000003179739,0.0007675709,0.0007998666,0.001001173,0.00003452094,0.00001435236,0.004277426],"genre_scores_gemma":[0.0005368834,0.9984779,0.0001342435,0.0001201869,0.00005173591,0.0001692767,0.00002289364,0.00003434236,0.0004525085],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9891551,"threshold_uncertainty_score":0.6164598,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2132565983","doi":"10.1136/adc.2010.190280","title":"Prevention of intellectual disability through screening for congenital hypothyroidism: how much and at what level?","year":2011,"lang":"en","type":"review","venue":"Archives of Disease in Childhood","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"European Society of Endocrinology; European Society for Paediatric Endocrinology","keywords":"Medicine; Intellectual disability; Newborn screening; Intelligence quotient; Pediatrics; Subclinical infection; Congenital hypothyroidism; Population; Borderline intellectual functioning; Psychiatry; Cognition; Thyroid; Environmental health; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.0972393208840912,"gpt":0.3323005211797314,"spread":0.2350612002956402,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007383656,0.0004135978,0.001507537,0.0001264282,0.00005554363,0.00001588301,0.000150552,0.0001054538,0.00002350387],"category_scores_gemma":[0.0004132963,0.0003295181,0.0008134357,0.0001220943,0.0004779103,0.0002156213,0.0002023879,0.0001624493,0.000001188262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002964156,"about_ca_system_score_gemma":0.0001813404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002485542,"about_ca_topic_score_gemma":0.00003924097,"domain_scores_codex":[0.9982732,0.0001352724,0.0006012596,0.00055456,0.000160536,0.0002752011],"domain_scores_gemma":[0.9981132,0.0008459794,0.0003637665,0.0004630951,0.00002399473,0.0001899795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.000787573,0.002684302,0.003234136,0.01055286,0.0009328951,0.000004617224,0.003012309,1.000023e-7,0.000001252237,0.0001646587,0.00004414128,0.9785811],"study_design_scores_gemma":[0.06439491,0.01407756,0.4262388,0.2147625,0.05072362,0.000183033,0.009739841,0.00009195899,0.0003117025,0.09981213,0.1144717,0.005192323],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04406504,0.9519678,0.0002504297,0.00004912724,0.00005059832,0.002697636,0.0007701698,0.0000143937,0.0001348007],"genre_scores_gemma":[0.1200414,0.8766878,0.002088196,0.000007517313,0.000038626,0.0001916479,0.000764532,0.0000533303,0.0001270173],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9733889,"threshold_uncertainty_score":0.9999157,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2083578935","doi":"10.1172/jci15990","title":"Thyroid functions of mouse cathepsins B, K, and L","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":223,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Shriners Hospitals for Children; McGill University","keywords":"Thyroglobulin; Cathepsin; Cathepsin B; Chemistry; Proteolytic enzymes; Thyroid; Cathepsin D; Cathepsin H; Biochemistry; Proteolysis; Molecular biology; Endocrinology; Internal medicine; Biology; Enzyme; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.0756598671017931,"gpt":0.3674383006342089,"spread":0.2917784335324158,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005339346,0.00005844864,0.0002970984,0.00006604842,0.00002590283,0.000005414198,0.00002101962,0.0000737223,0.00002175479],"category_scores_gemma":[0.001484143,0.00004159384,0.0001222077,0.00008872662,0.0001459437,0.00009242761,0.000004599545,0.0001702528,0.000004717426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001019818,"about_ca_system_score_gemma":0.000168605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007017984,"about_ca_topic_score_gemma":0.000003676307,"domain_scores_codex":[0.9988781,0.00008761422,0.0007436136,0.00006923942,0.0001605792,0.00006086213],"domain_scores_gemma":[0.998871,0.0001689186,0.0004898577,0.00009240802,0.0001913963,0.0001864335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002293528,0.0007752582,0.9796972,0.00003411926,0.0002471474,0.00001571497,0.000207857,0.00001446567,0.008795317,0.002325931,0.004250548,0.003407063],"study_design_scores_gemma":[0.01416138,0.006366587,0.9362708,0.0002042935,0.00101973,0.0003819071,0.0006728244,0.0001081333,0.01755372,0.01413537,0.00895199,0.0001732208],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970564,0.0006197029,0.0002236565,0.0008162615,0.0001623792,0.00007160004,0.000002325414,0.000003839822,0.001043886],"genre_scores_gemma":[0.9953169,0.0002932729,0.003189326,0.0002983799,0.00006829623,6.13423e-7,0.000002546247,0.000006725896,0.0008238953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04342639,"threshold_uncertainty_score":0.1776765,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1995526292","doi":"10.1016/j.neuro.2011.11.005","title":"Developmental thyroid hormone disruption: Prevalence, environmental contaminants and neurodevelopmental consequences","year":2011,"lang":"en","type":"article","venue":"NeuroToxicology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Ministry of Environment; UNICEF; U.S. Environmental Protection Agency","keywords":"Thyroid; Pediatrics; Congenital hypothyroidism; Medicine; Thyroid function; Iodine deficiency; Pregnancy; Incidence (geometry); Endocrinology; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.02781524134077695,"gpt":0.2428669763475574,"spread":0.2150517350067804,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005588638,0.0002436609,0.0002880442,0.00009499949,0.0001555659,0.00001071803,0.00008657632,0.0001085966,0.0004659976],"category_scores_gemma":[0.00002101477,0.0002127722,0.00004638773,0.00007128187,0.0005579394,0.0001203699,0.0001146389,0.0001555137,0.0001368224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006635617,"about_ca_system_score_gemma":0.00008098353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001405686,"about_ca_topic_score_gemma":0.000008471423,"domain_scores_codex":[0.9986637,0.00006290116,0.0002780802,0.000476233,0.0001702648,0.0003488436],"domain_scores_gemma":[0.999561,0.00003139582,0.00008393593,0.0001139207,0.000009022906,0.0002007208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006784537,0.00101828,0.6699228,0.00003250812,0.00008838112,0.001136893,0.0009675785,1.817405e-8,0.3202592,0.0001943037,0.0003811429,0.005320512],"study_design_scores_gemma":[0.003122057,0.001953377,0.9818178,0.00001042112,0.00007175239,0.002629864,0.0002843247,0.000003827391,0.008892635,0.0000878287,0.0009380658,0.0001880405],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930627,0.0007711891,0.00000836343,0.0001288341,0.0001152652,0.0009292694,0.00002731871,0.00006199503,0.004895098],"genre_scores_gemma":[0.9956127,0.0009788475,0.001236161,0.0009191494,0.00001674839,0.0001577829,0.00001779071,0.00002515828,0.001035655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.311895,"threshold_uncertainty_score":0.8676597,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2007264239","doi":"10.1371/journal.pgen.1004123","title":"Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease","year":2014,"lang":"en","type":"review","venue":"PLoS Genetics","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":218,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; National Health and Medical Research Council; Cedars-Sinai Medical Center; Deutsche Forschungsgemeinschaft; National Cancer Institute; Healthway; National Center for Research Resources; Newcastle University; Fonds Wetenschappelijk Onderzoek; Medical Research Council; Cardiff University; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Vlaamse regering; National Center for Advancing Translational Sciences; National Human Genome Research Institute; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust; Helsingin Yliopisto","keywords":"Biology; Thyroid; Identification (biology); Disease; Genetics; Thyroid peroxidase; Thyroid disease; Graves' disease; Computational biology; Internal medicine; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.05348059015993399,"gpt":0.3472213711093122,"spread":0.2937407809493782,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001936912,0.0005158972,0.002007493,0.0001564469,0.00008061475,0.00003637982,0.0001678563,0.0003105421,0.00001193799],"category_scores_gemma":[0.0003904111,0.0003711155,0.0003914486,0.0002167649,0.0003418336,0.00002432639,0.00009508774,0.0002760492,0.00002016087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005775684,"about_ca_system_score_gemma":0.0003325603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002925387,"about_ca_topic_score_gemma":0.00001060167,"domain_scores_codex":[0.9971734,0.000156546,0.001234019,0.0006594178,0.0004702182,0.0003064296],"domain_scores_gemma":[0.9974318,0.000236489,0.0009591624,0.00076506,0.0002526465,0.0003548381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0006171847,0.02572336,0.1237634,0.06482165,0.01764091,0.0003033156,0.0003538862,0.00001888356,0.0004709265,0.0001035497,0.001612569,0.7645704],"study_design_scores_gemma":[0.05409535,0.01873306,0.3307066,0.09066954,0.2952688,0.0003117118,0.0002815727,0.009669587,0.0004658416,0.0003531533,0.1916782,0.007766634],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07023638,0.9278601,0.00009846986,0.00002679509,0.00005855321,0.001333039,0.0002931986,0.0000422881,0.00005121643],"genre_scores_gemma":[0.02939754,0.9689653,0.0003651275,0.0000389744,0.0001147464,0.00005400779,0.0006273668,0.0001118256,0.0003251423],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7568038,"threshold_uncertainty_score":0.9998741,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1661646150","doi":"10.1073/pnas.242322099","title":"Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice","year":2002,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":207,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; National Institute on Aging; York University; U.S. Department of Veterans Affairs","keywords":"Thyrotropin receptor; Sodium-iodide symporter; Internal medicine; Endocrinology; Symporter; Thyroid; Thyroglobulin; Chemistry; Hormone; Receptor; Biology; Graves' disease; Medicine; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03208433033077889,"gpt":0.2788962654814607,"spread":0.2468119351506818,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004707979,0.0001659548,0.0003394363,0.0001974323,0.0001906321,0.00001906477,0.0003485739,0.0001129959,0.00003043032],"category_scores_gemma":[0.0003764568,0.0001129161,0.0001026197,0.0004795041,0.0005896344,0.0003017299,0.0001437633,0.0001696929,0.000002359738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006940324,"about_ca_system_score_gemma":0.00002416125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005077879,"about_ca_topic_score_gemma":1.650265e-7,"domain_scores_codex":[0.9975863,0.00001160883,0.0004591666,0.0003340034,0.001389691,0.0002192416],"domain_scores_gemma":[0.9989876,0.0001339251,0.0005936217,0.0000168588,0.000195491,0.00007257668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000095273,0.0003821874,0.02180925,0.0001136471,0.0001155468,3.052226e-8,0.0003196857,0.00002037265,0.9672995,0.005453876,0.002757751,0.001632926],"study_design_scores_gemma":[0.003032327,0.0009031493,0.07729492,0.0005897343,0.0003441056,0.00008060248,0.00151357,0.002563396,0.9064901,0.006420784,0.0003762014,0.0003910559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861292,0.007200301,0.000001945874,0.002180979,0.00001576014,0.0003359226,0.00005230677,0.00001189893,0.004071634],"genre_scores_gemma":[0.9961204,0.001260699,0.002255993,0.0001484746,0.00002708166,0.0000131947,2.72712e-7,0.00001001354,0.0001638714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0608093,"threshold_uncertainty_score":0.4604586,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4251049851","doi":"10.1159/000358198","title":"European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism","year":2014,"lang":"en","type":"article","venue":"Hormone Research in Paediatrics","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Istituto Superiore di Sanità; European Society for Paediatric Endocrinology","keywords":"Congenital hypothyroidism; Medicine; Pediatrics; Pediatric endocrinology; Newborn screening; Guideline; MEDLINE; Family medicine; Grading (engineering); Expert opinion; Intensive care medicine; Thyroid; Internal medicine; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.1260650494995859,"gpt":0.3812406994920275,"spread":0.2551756499924416,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00157099,0.000202011,0.000369315,0.000424318,0.0001215528,0.00001898142,0.000139697,0.00009189111,0.000002636511],"category_scores_gemma":[0.0004961052,0.0001754381,0.0001912991,0.0006074847,0.0002235661,0.00002667183,0.0002067753,0.0002860347,0.00001418031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005629595,"about_ca_system_score_gemma":0.00004373163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006335492,"about_ca_topic_score_gemma":0.000006422526,"domain_scores_codex":[0.9976078,0.0001914222,0.0005122603,0.0004608486,0.0005530242,0.0006746887],"domain_scores_gemma":[0.9980479,0.0009510592,0.0001025884,0.0003464701,0.0003439927,0.0002079251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.002119716,0.002999592,0.2884705,0.0009740539,0.001093324,0.0006006286,0.0004105031,0.00007233033,0.0003949175,0.008443646,0.3673147,0.3271061],"study_design_scores_gemma":[0.06146124,0.01440457,0.7754198,0.0001742108,0.000864468,0.0001100481,0.00289044,0.003656076,0.0008076362,0.004559079,0.1346119,0.001040585],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9334841,0.05663169,0.0003662499,0.00322387,0.00008232699,0.001937575,0.00008676456,0.00004893655,0.004138466],"genre_scores_gemma":[0.9215277,0.06659547,0.01088804,0.0001484254,0.0002815246,0.0002201242,0.00004844129,0.00005021752,0.0002400577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4869493,"threshold_uncertainty_score":0.7154158,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136386868","doi":"10.1210/jc.2002-020805","title":"A Randomized Comparison of Radioiodine Doses in Graves’ Hyperthyroidism","year":2003,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":204,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Euthyroid; Medicine; Iodine; Thyroid; Nuclear medicine; Randomized controlled trial; Graves' disease; Radioiodine therapy; Radioactive iodine; Internal medicine; Thyroid cancer; Chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.07596975595735603,"gpt":0.419662693245019,"spread":0.3436929372876629,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002588968,0.0002138067,0.003199192,0.0002392336,0.00004299539,0.000004429934,0.000241463,0.0001328641,0.00008663008],"category_scores_gemma":[0.004312801,0.0001124515,0.000772621,0.0002367081,0.0007346771,0.00006203786,0.00003330203,0.0008558894,0.0000120265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001214112,"about_ca_system_score_gemma":0.0002003521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005620997,"about_ca_topic_score_gemma":0.00001300301,"domain_scores_codex":[0.9943972,0.001977225,0.002777816,0.0001531715,0.0003361456,0.0003584587],"domain_scores_gemma":[0.9952939,0.002682878,0.001300533,0.0003609206,0.0002002916,0.0001614741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4817265,0.0137296,0.3943978,0.0000819854,0.006262774,0.0007761813,0.003256186,0.0002047511,0.002904542,0.06247468,0.004411298,0.02977378],"study_design_scores_gemma":[0.7948877,0.001058724,0.1652117,0.0000801905,0.003104028,0.001407825,0.000851303,0.00005680495,0.004105351,0.01065042,0.01839766,0.0001883304],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9429485,0.05185444,0.0001199531,0.002348287,0.0006725637,0.0003797606,0.000001903905,0.000007654442,0.001666888],"genre_scores_gemma":[0.9872897,0.01077274,0.001072507,0.0004931387,0.0001703371,0.000005074779,0.000001232753,0.00001710098,0.0001781326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3131612,"threshold_uncertainty_score":0.5163137,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012703397","doi":"10.3390/nu5041384","title":"Iodine and Mental Development of Children 5 Years Old and Under: A Systematic Review and Meta-Analysis","year":2013,"lang":"en","type":"review","venue":"Nutrients","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":204,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Nutrition International; McGill University","funders":"","keywords":"Iodine deficiency; Medicine; Randomized controlled trial; Cohort; Iodised salt; Cohort study; Confounding; Pediatrics; Iodine; Meta-analysis; Prospective cohort study; Internal medicine; Thyroid","retraction":null,"screen_n_in":null,"score":{"opus":0.05390994149178271,"gpt":0.3255129874281051,"spread":0.2716030459363225,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001800069,0.0003695757,0.005761479,0.0002411402,0.00004409793,0.00002040644,0.00006474511,0.0001123694,0.00007698837],"category_scores_gemma":[0.00002084452,0.0002254973,0.0005051202,0.0003242574,0.00005602084,0.00003821463,0.0001071129,0.00009431107,0.00001320966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004295497,"about_ca_system_score_gemma":0.00004399749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002253467,"about_ca_topic_score_gemma":0.00000307679,"domain_scores_codex":[0.9982634,0.00008514208,0.0008182185,0.0004036185,0.0002720231,0.000157619],"domain_scores_gemma":[0.9989573,0.00003642818,0.000484365,0.0003234089,0.00003761023,0.0001609251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.000003480041,0.0002850209,0.00035742,0.7325595,0.2587939,0.000004371615,0.0001108105,2.141592e-9,5.148512e-8,0.00001769923,0.0002206881,0.007647035],"study_design_scores_gemma":[0.0009036792,0.0000691326,0.0003847485,0.02306255,0.9708031,0.00006912707,0.00001636497,1.891968e-7,3.498657e-7,0.0000064715,0.004477428,0.000206815],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001018615,0.9947641,0.000002407273,0.00003192312,0.000007934949,0.004046264,0.00009570352,0.000009577157,0.00002345249],"genre_scores_gemma":[0.0003343379,0.9978147,0.0004114681,0.00009780593,0.000003171284,0.0003293567,0.0002870307,0.00002456451,0.0006975722],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7120092,"threshold_uncertainty_score":0.9195512,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1585231636","doi":"10.1159/000363153","title":"The Role of Thyroid Hormones for Brain Development and Cognitive Function","year":2014,"lang":"en","type":"review","venue":"Endocrine development","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Mental Health Research Canada; Hospital for Sick Children","funders":"","keywords":"Neuropsychology; Brain development; Offspring; Hormone; Thyroid; Neuroimaging; Physiology; Human brain; Brain function; Cognition; Medicine; Brain size; Thyroid function; Pregnancy; Psychology; Developmental psychology; Neuroscience; Endocrinology; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.01894177773949219,"gpt":0.3044301800502247,"spread":0.2854884023107325,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002512995,0.0004388104,0.001193406,0.0001420744,0.0002673639,0.00002363504,0.00009054534,0.00008602844,0.00000804886],"category_scores_gemma":[0.0001624707,0.0002655213,0.0001841765,0.0001287872,0.0000673663,0.00002713875,0.0001043218,0.0001413651,0.00002750161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008721102,"about_ca_system_score_gemma":0.0006221417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004475296,"about_ca_topic_score_gemma":0.00001740998,"domain_scores_codex":[0.9981514,0.00005148998,0.000765131,0.0004047018,0.0002622946,0.0003650225],"domain_scores_gemma":[0.9986529,0.0005348342,0.0003619966,0.0001899824,0.0001414586,0.0001188739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001175528,0.000117096,0.00005229969,0.002536651,0.001173719,0.000004025642,0.0001866629,9.38244e-9,0.000001552868,0.0002474496,0.0006801205,0.9948829],"study_design_scores_gemma":[0.00171352,0.0002814798,0.000474705,0.002622956,0.001053511,0.00005615731,0.0001846736,7.651857e-7,0.0001891448,0.00009233168,0.9930728,0.0002579468],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002655931,0.9961121,0.0003141572,0.00006377647,0.0001245249,0.002133006,0.00001561532,0.00003282606,0.0009383825],"genre_scores_gemma":[0.0009478584,0.9903904,0.002683533,0.00006612005,0.00008548911,0.00158529,0.00069132,0.00007468792,0.003475283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9946249,"threshold_uncertainty_score":0.9999797,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2086555083","doi":"10.1210/jc.2003-030139","title":"Does a Combination Regimen of Thyroxine (T<sub>4</sub>) and 3,5,3′-Triiodothyronine Improve Depressive Symptoms Better Than T<sub>4</sub>Alone in Patients with Hypothyroidism? Results of a Double-Blind, Randomized, Controlled Trial","year":2003,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Joseph’s Healthcare Hamilton; Hamilton Health Sciences; McMaster University","funders":"McMaster University","keywords":"Levothyroxine; Medicine; Triiodothyronine; Depression (economics); Regimen; Internal medicine; Placebo; Mood; Depressive symptoms; Randomized controlled trial; Thyroid; Pediatrics; Psychiatry; Anxiety","retraction":null,"screen_n_in":null,"score":{"opus":0.01347938651753591,"gpt":0.2839964814620206,"spread":0.2705170949444846,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003415416,0.0005044373,0.005198795,0.0005085458,0.0000795809,0.00001519222,0.0002840822,0.0003036342,0.000004159279],"category_scores_gemma":[0.003212153,0.0002288025,0.0007947516,0.0003353974,0.001100166,0.0002350787,0.00008913717,0.001002726,0.000001835203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000325321,"about_ca_system_score_gemma":0.0002802818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004121148,"about_ca_topic_score_gemma":0.00003012702,"domain_scores_codex":[0.9916243,0.002266471,0.004289279,0.0004373372,0.0008126827,0.0005699554],"domain_scores_gemma":[0.9899149,0.003641688,0.004757561,0.0006061555,0.0008376823,0.0002420312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9714969,0.004165293,0.01045523,0.00002342475,0.003276182,0.00004768385,0.0002742654,0.00001132674,0.006087967,0.0004507504,0.00005144815,0.00365952],"study_design_scores_gemma":[0.8952337,0.004602564,0.04035899,0.000112807,0.004196851,0.00005390285,0.0000667342,0.00001093738,0.05379121,0.001346547,0.00003022164,0.0001955515],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879642,0.004666731,0.00005595394,0.001580297,0.0007340968,0.004818689,0.0000268098,0.00001290782,0.0001402744],"genre_scores_gemma":[0.9951647,0.004056981,0.0001360396,0.0002125548,0.0002257637,0.0001094294,0.00001648232,0.0000475553,0.00003052019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07626323,"threshold_uncertainty_score":0.9330295,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3106666427","doi":"10.1089/thy.2020.0720","title":"Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document","year":2020,"lang":"en","type":"review","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"Levothyroxine; Medicine; Clinical trial; Pediatrics; Guideline; Family medicine; Internal medicine; Thyroid; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.1524173530393768,"gpt":0.3578536281375196,"spread":0.2054362750981428,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002928931,0.001001498,0.004051408,0.0009201741,0.00009670886,0.00007059006,0.0003069527,0.0004430413,0.0001223708],"category_scores_gemma":[0.001216571,0.0008298446,0.001049363,0.001587911,0.0002480294,0.0001851489,0.0001433515,0.000733921,0.0001406111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007002495,"about_ca_system_score_gemma":0.00153683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006013589,"about_ca_topic_score_gemma":0.00009050634,"domain_scores_codex":[0.9953865,0.0004342506,0.00190888,0.0009913462,0.0006178959,0.000661122],"domain_scores_gemma":[0.995671,0.001720302,0.001027272,0.00101755,0.0001864515,0.0003774343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006851068,0.004048296,0.001189705,0.01873985,0.001528304,0.001905083,0.0004150172,0.000048755,0.0001646896,0.001481051,0.009322537,0.9604716],"study_design_scores_gemma":[0.01842234,0.004838846,0.0006571163,0.07900451,0.008261715,0.0003570354,0.0001517896,0.0003224071,0.0001538442,0.0002901994,0.8856669,0.001873263],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009955883,0.9940097,0.00004520224,0.0009013819,0.0001210442,0.003092485,0.0001949978,0.0001444033,0.0004951509],"genre_scores_gemma":[0.003336874,0.9912143,0.003334603,0.0001999642,0.00008657753,0.0003745269,0.0003881614,0.0001826879,0.0008822583],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9585984,"threshold_uncertainty_score":0.9994152,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2505565526","doi":"10.17925/ee.2013.09.01.40","title":"A Review of the Pharmacokinetics of Levothyroxine for the Treatment of Hypothyroidism","year":2010,"lang":"en","type":"review","venue":"touchREVIEWS in Endocrinology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Levothyroxine; Medicine; Pharmacokinetics; Dosing; Hormone; Thyroid hormones; Pediatrics; Pharmacology; Endocrinology","retraction":null,"screen_n_in":null,"score":{"opus":0.080055810424067,"gpt":0.4014444245827009,"spread":0.3213886141586339,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002139821,0.0005465217,0.004823199,0.0001505327,0.00003160296,0.000001321168,0.0005385861,0.0001939747,0.0001237367],"category_scores_gemma":[0.0003149083,0.0002405504,0.001956763,0.0004876423,0.0004272976,0.00001408333,0.00008570738,0.0003217404,0.000006286642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008540431,"about_ca_system_score_gemma":0.0003268829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000583867,"about_ca_topic_score_gemma":0.00003461864,"domain_scores_codex":[0.9967128,0.0002692111,0.00206988,0.0003851802,0.0001695636,0.0003933637],"domain_scores_gemma":[0.9958605,0.000812153,0.001652493,0.001469963,0.0001548984,0.00005000478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002580287,0.00102081,0.00003746416,0.1061284,0.000461551,0.000004684588,0.00003613585,5.850583e-8,0.00002591586,0.0003605606,0.001298624,0.8906],"study_design_scores_gemma":[0.002121588,0.0008118811,0.00002473416,0.04517524,0.007206406,0.00012665,0.000005516405,8.841395e-7,0.0003350661,0.00004467736,0.9440109,0.0001364196],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003097171,0.9900742,0.000007947941,0.0003684884,0.0004349084,0.008376543,0.0002190992,0.000007522951,0.0004802825],"genre_scores_gemma":[0.00002582616,0.9975461,0.0003655392,0.0001900252,0.00009605598,0.001398296,0.00005827917,0.00005623023,0.000263679],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9427123,"threshold_uncertainty_score":0.9809361,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2157934726","doi":"10.4021/jocmr2010.03.281w","title":"Prevalence of Thyroid Dysfunction Among Greek Type 2 Diabetic Patients Attending an Outpatient Clinic","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Medicine Research","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"","funders":"","keywords":"Medicine; Thyroid dysfunction; Internal medicine; Diabetes mellitus; Outpatient clinic; Thyroid; Type 2 diabetes; Endocrinology; Body mass index; Cholesterol; Thyroid disorder; Gastroenterology","retraction":null,"screen_n_in":null,"score":{"opus":0.1325389332949292,"gpt":0.4840102755509083,"spread":0.351471342255979,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.007285344,0.0001680855,0.0009122837,0.0004594507,0.00009009861,0.00001199761,0.0003057533,0.0002626712,0.0005396153],"category_scores_gemma":[0.01551065,0.0001054454,0.0002365298,0.0004865764,0.0009024285,0.0003024062,0.00008454653,0.002315468,0.00003516987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004608892,"about_ca_system_score_gemma":0.0003377406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005351447,"about_ca_topic_score_gemma":0.0000173399,"domain_scores_codex":[0.9944851,0.0005964453,0.002218862,0.0003111199,0.001978135,0.0004102857],"domain_scores_gemma":[0.9932098,0.001912817,0.0009768126,0.0005230987,0.002675247,0.0007022017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001964426,0.002637072,0.9704233,0.0001929369,0.000135145,0.00006459033,0.0001631508,4.029571e-7,0.0007545703,0.00001713948,0.002351638,0.02129561],"study_design_scores_gemma":[0.008539381,0.03854186,0.9508407,0.0006106162,0.0002537791,0.00002245026,0.0002429507,0.0000482525,0.00015225,0.0002610809,0.0004099309,0.00007680913],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947592,0.0004956194,0.00001569244,0.0007269235,0.002055211,0.0004712396,0.000003551365,0.000008461743,0.001464114],"genre_scores_gemma":[0.9963579,0.001070856,0.0002785955,0.00008465772,0.001079929,0.000004082,0.00000849704,0.0000246921,0.001090839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03590479,"threshold_uncertainty_score":0.9999862,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2085438574","doi":"10.1016/j.ygcen.2014.03.015","title":"Mechanisms of crosstalk between endocrine systems: Regulation of sex steroid hormone synthesis and action by thyroid hormones","year":2014,"lang":"en","type":"review","venue":"General and Comparative Endocrinology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Genomics; University of Ottawa","funders":"","keywords":"Biology; Hormone; Gonad; Endocrine system; Endocrinology; Internal medicine; Sexual differentiation; Thyroid; Steroid hormone; Sex hormone receptor; Sex steroid; Vertebrate; Steroid; Estrogen receptor; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.07094166196304667,"gpt":0.3386222121628067,"spread":0.26768055019976,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006604481,0.0004656763,0.003093547,0.0002226909,0.00008234522,0.00001443696,0.00008386691,0.0001756602,0.00000799508],"category_scores_gemma":[0.00001307847,0.0003441171,0.0001813189,0.0001261659,0.0002508286,0.00006082947,0.00009980855,0.0001768343,0.000003617114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000403644,"about_ca_system_score_gemma":0.0000436367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00018982,"about_ca_topic_score_gemma":0.000006017029,"domain_scores_codex":[0.9979331,0.0002827861,0.0007996347,0.0004856592,0.0001813498,0.0003174814],"domain_scores_gemma":[0.9986213,0.0002103032,0.0006828718,0.0002864283,0.00009310578,0.0001059459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005354176,0.0007017648,0.0008540018,0.01798241,0.005555034,0.00003008903,0.0003764848,0.000005637181,0.02333717,0.009148889,0.00274837,0.9387248],"study_design_scores_gemma":[0.01358511,0.01380778,0.01492108,0.006203559,0.01791838,0.002407161,0.001532259,0.0002618733,0.03446007,0.002250111,0.8901088,0.002543825],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05993991,0.9379352,0.0005757025,0.00002338568,0.00007263453,0.0008739674,0.000286104,0.00002613686,0.0002669101],"genre_scores_gemma":[0.2976818,0.7010236,0.0001624449,0.000004149212,0.00006087175,0.000128598,0.0002726232,0.00002016965,0.0006457894],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9361809,"threshold_uncertainty_score":0.9999011,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012868945","doi":"10.1016/j.atherosclerosis.2013.07.056","title":"Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist","year":2013,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Agonist; Internal medicine; Endocrinology; Medicine; Thyroid hormone receptor; Thyroid; Receptor; Hormone","retraction":null,"screen_n_in":null,"score":{"opus":0.01368847017811,"gpt":0.2233280165257992,"spread":0.2096395463476892,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000816414,0.0003395694,0.0006079315,0.0001746541,0.00009782737,0.0000290334,0.0001261306,0.0001420754,0.0001912838],"category_scores_gemma":[0.00005555095,0.0002625877,0.000130241,0.000524993,0.0001506555,0.0001830894,0.00004341572,0.0001861984,0.0001592966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001776415,"about_ca_system_score_gemma":0.00007527873,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01421455,"about_ca_topic_score_gemma":0.0007139057,"domain_scores_codex":[0.9982485,0.00004587562,0.000445094,0.0004532567,0.0002949761,0.0005122737],"domain_scores_gemma":[0.9989514,0.00007977211,0.0001674542,0.0004486737,0.0001279014,0.0002248293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00185635,0.00186402,0.6902421,0.00008051292,0.0002314602,0.000006871282,0.00128807,0.00002209002,0.2993757,0.000006283905,0.001438196,0.003588402],"study_design_scores_gemma":[0.01395546,0.005324265,0.9506747,0.000284607,0.0001154402,0.000006119963,0.0008230297,0.0004277719,0.02766946,0.0000045695,0.0003600417,0.0003545257],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962528,0.001751256,0.00003345732,0.000304731,0.00004938883,0.001074271,0.00004150196,0.0001131637,0.0003793834],"genre_scores_gemma":[0.9966465,0.001350682,0.001078811,0.0002031864,0.00003670219,0.0002021106,0.00008155705,0.00007641967,0.0003240023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2717062,"threshold_uncertainty_score":0.9999827,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2000975299","doi":"10.1159/000182549","title":"Comparison of Epidemiological Data on Congenital Hypothyroidism in Europe with Those of Other Parts in the World","year":2008,"lang":"en","type":"article","venue":"Hormone Research","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":156,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Incidence (geometry); Demography; Epidemiology; Geography; Ethnic group; Medicine; Political science; Sociology; Law","retraction":null,"screen_n_in":null,"score":{"opus":0.4109151682761346,"gpt":0.4813697364533603,"spread":0.07045456817722567,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001339397,0.000103642,0.0004227445,0.0002408291,0.00003869383,0.000003042327,0.0003051592,0.00004472961,0.00001884724],"category_scores_gemma":[0.000590933,0.00005312903,0.00002302719,0.0009357461,0.000426683,0.00004114758,0.0001147821,0.0004460288,0.00002191373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002126236,"about_ca_system_score_gemma":0.000091889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006170598,"about_ca_topic_score_gemma":0.0005484342,"domain_scores_codex":[0.9979525,0.0005599379,0.0003389443,0.0002696158,0.0005649454,0.0003140668],"domain_scores_gemma":[0.9980807,0.001002654,0.00005978337,0.0007074086,0.0000910017,0.0000584667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002681012,0.00387042,0.9697778,0.00001195817,0.00005224513,0.0003663831,0.0009744668,0.00001847688,0.001220937,0.0009778081,0.0191105,0.0009379673],"study_design_scores_gemma":[0.0034349,0.00243019,0.9909239,0.00004709445,0.00001197844,0.00001841231,0.0005041658,0.0002561307,0.0005992291,0.0001262308,0.001583442,0.000064319],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777747,0.006093227,0.000003699364,0.0008901209,0.000004269635,0.0005309893,0.00002440295,0.000004941962,0.0146736],"genre_scores_gemma":[0.9988622,0.0004073637,0.0001638302,0.00005885058,0.00001642517,0.000023338,0.000036543,0.0000127456,0.0004186739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02114609,"threshold_uncertainty_score":0.2166539,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1611526734","doi":"10.1089/105072501300176471","title":"The Various Effects of Amiodarone on Thyroid Function","year":2001,"lang":"en","type":"review","venue":"Thyroid","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":154,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Alberta Innovates - Health Solutions","keywords":"Amiodarone; Medicine; Levothyroxine; Triiodothyronine; Thyroiditis; Internal medicine; Thyroid; Deiodinase; Iodothyronine deiodinase; Endocrinology; Thyroid function; Autoimmune thyroiditis; Thyroid function tests; Hormone; Thyroidectomy; Gastroenterology; Atrial fibrillation","retraction":null,"screen_n_in":null,"score":{"opus":0.01746868107633487,"gpt":0.29605502982231,"spread":0.2785863487459752,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000194089,0.0006111508,0.001851529,0.0001910838,0.000208425,0.00002647535,0.0002319564,0.000355215,0.00002504808],"category_scores_gemma":[0.000144547,0.0003406506,0.0007709684,0.0004995376,0.0001373498,0.00003476774,0.0000688142,0.0005342354,0.0005633874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000188636,"about_ca_system_score_gemma":0.0002274434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000568595,"about_ca_topic_score_gemma":0.000009732184,"domain_scores_codex":[0.9977102,0.0001791605,0.0006520685,0.0004945723,0.0004963106,0.0004676981],"domain_scores_gemma":[0.9976254,0.0005798767,0.0004932625,0.00107301,0.00007088594,0.0001576101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002033489,0.000594155,0.000009659789,0.004633939,0.0008966255,0.0001137105,0.00002680247,2.63321e-7,0.000008384517,0.0005294755,0.007558017,0.9854256],"study_design_scores_gemma":[0.002186598,0.003838511,0.0001600178,0.005061207,0.004235934,0.0001228617,0.00001117051,0.000001446269,0.00001227775,0.0003000859,0.9837827,0.0002871919],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009069745,0.9847484,0.00004799529,0.00006079908,0.0006444952,0.002001886,0.00001791689,0.00009994642,0.0122879],"genre_scores_gemma":[0.0005497996,0.9914175,0.00002666256,0.0001099842,0.0002831262,0.0002101718,0.0001760231,0.0001107637,0.007115937],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9851384,"threshold_uncertainty_score":0.9999046,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2020444746","doi":"10.1159/000124741","title":"Thyroid Hormones Influence the Development of Hippocampal Glucocorticoid Receptors in the Rat: A Mechanism for the Effects of Postnatal Handling on the Development of the Adrenocortical Stress Response","year":2008,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Endocrinology; Internal medicine; Glucocorticoid; Glucocorticoid receptor; Corticosterone; Hippocampal formation; Propylthiouracil; Hypothalamus; Hormone; Antiglucocorticoid; Thyroid; Hippocampus; Receptor; Biology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.0188314688653026,"gpt":0.2594739586760038,"spread":0.2406424898107012,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001481346,0.0002525223,0.0003913723,0.00008804361,0.0003654831,0.000006373578,0.0006226539,0.00005160299,0.000005248091],"category_scores_gemma":[0.001342244,0.00009692096,0.0001463125,0.0003013358,0.0004594255,0.00002859324,0.0001895952,0.0003457795,0.000003597807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004431077,"about_ca_system_score_gemma":0.0004593287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002492301,"about_ca_topic_score_gemma":0.00008644425,"domain_scores_codex":[0.9976449,0.0004725684,0.000709698,0.0002892893,0.0004538297,0.0004297288],"domain_scores_gemma":[0.9951206,0.003715806,0.0003122733,0.0006835551,0.000134059,0.00003374098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.04126993,0.006327753,0.1876293,0.0009976542,0.002002571,0.0005370651,0.1026187,0.0003859512,0.6070856,0.02233614,0.0006597369,0.02814966],"study_design_scores_gemma":[0.003120251,0.00131381,0.5071716,0.0001251485,0.0001199135,0.0001765119,0.001921679,0.0000384523,0.485532,0.0001534386,0.0002237944,0.0001034498],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937372,0.0006178991,0.00006185795,0.002791414,0.0002781123,0.002471146,0.000007085977,0.00001108028,0.00002421621],"genre_scores_gemma":[0.9985035,0.0002002401,0.0002362043,0.0005707413,0.0000148484,0.0004082108,0.000003237547,0.00002157781,0.00004142661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3195423,"threshold_uncertainty_score":0.3952322,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2156140430","doi":"10.1136/bmj.d2238","title":"Levothyroxine dose and risk of fractures in older adults: nested case-control study","year":2011,"lang":"en","type":"article","venue":"BMJ","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Institute for Clinical Evaluative Sciences; Women's College Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Levothyroxine; Odds ratio; Confidence interval; Cohort; Population; Nested case-control study; Cohort study; Internal medicine; Surgery; Pediatrics; Physical therapy; Thyroid","retraction":null,"screen_n_in":null,"score":{"opus":0.0127793447737243,"gpt":0.2861601589046503,"spread":0.273380814130926,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001302087,0.0001055679,0.0002596444,0.00008305708,0.00002032484,0.000002613829,0.00002396975,0.00004820108,0.0001223773],"category_scores_gemma":[0.00008790993,0.00007358556,0.00003239807,0.00008276809,0.00002716966,0.00003691981,0.00001219228,0.00008124927,0.000004585082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008586161,"about_ca_system_score_gemma":0.00001658211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003973146,"about_ca_topic_score_gemma":0.001916785,"domain_scores_codex":[0.9993446,0.00006046204,0.0002245266,0.0001626814,0.00009186469,0.0001158915],"domain_scores_gemma":[0.9995516,0.00004855215,0.00009449807,0.0002116472,0.00003352955,0.00006017556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001114103,0.001978153,0.9812762,0.000017077,0.000181301,0.001854303,0.005224876,6.21994e-7,0.0000165227,0.000003342478,0.0002610228,0.008072487],"study_design_scores_gemma":[0.02064237,0.0008286056,0.974857,0.00004295081,0.0002653948,0.0001762495,0.002988725,0.00004217436,0.00005557785,0.00002595131,0.0000106926,0.00006435003],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965259,0.001372434,0.000009244314,0.00007589754,0.00002607324,0.001367857,0.00001975475,0.0000152092,0.0005875844],"genre_scores_gemma":[0.9995447,0.00003701149,0.0001706563,0.00008259961,0.00002409861,0.00004995597,0.000002273665,0.00001194242,0.00007674365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01952827,"threshold_uncertainty_score":0.6006235,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2123696673","doi":"10.1210/jc.2012-2556","title":"Diiodothyropropionic Acid (DITPA) in the Treatment of MCT8 Deficiency","year":2012,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Pediatric Endocrine Society","keywords":"Thyroid; Internal medicine; Endocrinology; Medicine; Hormone; Psychomotor retardation; Hypermetabolism; Triiodothyronine","retraction":null,"screen_n_in":null,"score":{"opus":0.07372430416543763,"gpt":0.4003137198487616,"spread":0.3265894156833239,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001118655,0.0001843828,0.0009633749,0.0001264559,0.00006641276,0.000004383129,0.0003184239,0.00009800857,0.00007040884],"category_scores_gemma":[0.0003925355,0.00007552595,0.0004867752,0.0002146978,0.000393729,0.00009726331,0.00002805218,0.0004349058,0.00003277124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002539649,"about_ca_system_score_gemma":0.0001303852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000053397,"about_ca_topic_score_gemma":0.0000112167,"domain_scores_codex":[0.9970418,0.0006962881,0.001336943,0.0001086695,0.0003503552,0.0004659039],"domain_scores_gemma":[0.9978096,0.000801456,0.0006888607,0.0004645066,0.0001107659,0.0001248313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004810734,0.02867169,0.7158241,0.00003534832,0.001412749,0.0003511471,0.007629628,0.00001806791,0.002056192,0.01321664,0.001508068,0.2244656],"study_design_scores_gemma":[0.009669265,0.00270162,0.9422235,0.00001818746,0.001383745,0.00112868,0.0008911548,0.000002899577,0.001383575,0.001010328,0.03950609,0.00008090662],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9194893,0.07440124,0.00002888981,0.004092252,0.0007830531,0.0002725684,0.000002951662,0.000005387439,0.0009243941],"genre_scores_gemma":[0.9733354,0.02500606,0.0002413552,0.0006111444,0.0006721345,0.000006811151,0.000001245255,0.00001272506,0.0001130615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2263994,"threshold_uncertainty_score":0.3079859,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2005144296","doi":"10.1542/peds.105.3.515","title":"Psychoeducational Outcome in Children With Early-Treated Congenital Hypothyroidism","year":2000,"lang":"en","type":"article","venue":"PEDIATRICS","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Pediatrics; Spelling; Congenital hypothyroidism; Learning disability; Cognition; Developmental psychology; Comprehension; Audiology; Thyroid; Psychiatry; Psychology; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01051258871890946,"gpt":0.2584581853592673,"spread":0.2479455966403579,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003639524,0.000151443,0.000185101,0.0001409176,0.00004043088,0.00001580614,0.00005703005,0.00006811057,0.0004529812],"category_scores_gemma":[0.00001306235,0.0001181051,0.00004902906,0.0003969702,0.00003220878,0.00007158188,0.000006127595,0.0001340204,0.0003790347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005296825,"about_ca_system_score_gemma":0.00007597336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003680259,"about_ca_topic_score_gemma":0.00003068759,"domain_scores_codex":[0.9990883,0.00001285749,0.0002028792,0.0002410715,0.000219292,0.0002356053],"domain_scores_gemma":[0.9995843,0.00002117388,0.00003586477,0.0001929007,0.00003486084,0.000130934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001288588,0.0006222663,0.9961768,0.000002655813,0.00004450021,0.00001636672,0.00009643161,0.000004083045,0.000002584133,0.00002189067,0.0005880278,0.002295534],"study_design_scores_gemma":[0.004286038,0.000231539,0.9948516,0.000001744105,0.0001479079,0.00006705106,0.0000156929,0.00000368366,0.000005776735,0.00006394345,0.0001983126,0.0001267235],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920053,0.001010038,0.000002231578,0.0002872719,0.00003260291,0.0003829193,0.00003248841,0.00004941369,0.006197723],"genre_scores_gemma":[0.9956594,0.0002039046,0.0003430351,0.0001725664,0.0001623629,0.00003316295,0.0001376944,0.00002514641,0.003262701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004157179,"threshold_uncertainty_score":0.4959826,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2037962057","doi":"10.1159/000242547","title":"Regional Variations of Iodine Nutrition and Thyroid Function during the Neonatal Period in Europe","year":2009,"lang":"en","type":"article","venue":"Biology of the Neonate","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Iodine deficiency; Iodine; Congenital hypothyroidism; Medicine; Thyroid function; Goiter; Thyroid; Pediatrics; Endocrinology; Newborn screening; Physiology; Internal medicine; Chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.009941727630041077,"gpt":0.2352213254404744,"spread":0.2252795978104333,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000599118,0.00005950833,0.0001167,0.00004654829,0.00005752452,0.000001509956,0.00004905988,0.00004408656,0.000008853172],"category_scores_gemma":[0.00003622578,0.00003278036,0.00003519248,0.000147416,0.0001079302,0.00002153176,0.00002053723,0.0000611652,9.014747e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001169464,"about_ca_system_score_gemma":0.00002205999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003845821,"about_ca_topic_score_gemma":0.00001918181,"domain_scores_codex":[0.9995944,0.00004694109,0.0001370384,0.00009692628,0.00004833222,0.00007630283],"domain_scores_gemma":[0.99971,0.00002168118,0.00007879236,0.0001248444,0.00005100234,0.00001367501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004792678,0.001755357,0.333931,0.0001455105,0.0003516857,0.00002059272,0.002078317,0.00004375217,0.5855376,0.03222874,0.0007486782,0.03836602],"study_design_scores_gemma":[0.003063726,0.0004030721,0.9910752,0.00003520561,0.00004426079,0.00006000405,0.00005380066,0.00004279426,0.001108109,0.002507596,0.001572189,0.00003402174],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900286,0.003291202,0.00002082812,0.006186563,0.00005606392,0.0002077041,0.00001252173,0.00000644173,0.0001900649],"genre_scores_gemma":[0.9992302,0.0003635648,0.00007219646,0.0001313118,0.00002508922,0.000005415444,0.00001672368,0.000002964533,0.0001525412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6571442,"threshold_uncertainty_score":0.1336744,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3198926211","doi":"10.1001/jamapsychiatry.2021.2506","title":"Association of Hypothyroidism and Clinical Depression","year":2021,"lang":"en","type":"review","venue":"JAMA Psychiatry","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Medicine; Depression (economics); Odds ratio; Subclinical infection; Population; Psychiatry; PsycINFO; Meta-analysis; Internal medicine; MEDLINE","retraction":null,"screen_n_in":null,"score":{"opus":0.03188240282713642,"gpt":0.3818279958665081,"spread":0.3499455930393717,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002644023,0.0002419712,0.001728462,0.0000859756,0.00003569542,0.00001806244,0.00006055219,0.0007268247,0.00004825844],"category_scores_gemma":[0.0002334677,0.0001786173,0.0006753042,0.0001634534,0.00002456747,0.000038462,0.00006252814,0.0004435797,0.00002294842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005750408,"about_ca_system_score_gemma":0.000393296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001027536,"about_ca_topic_score_gemma":0.000008736862,"domain_scores_codex":[0.9982634,0.0001727939,0.0007667287,0.0003869979,0.0002491636,0.0001609615],"domain_scores_gemma":[0.9985757,0.0001997274,0.0006690628,0.0003651522,0.00006656594,0.0001238244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001576751,0.0005932689,0.08507466,0.003499017,0.0009929568,0.000009084328,0.000007685279,3.125438e-9,3.962155e-8,0.00005105269,0.04103285,0.8687236],"study_design_scores_gemma":[0.002897789,0.0001598468,0.01595463,0.01074176,0.005339741,0.00005055872,0.00002099706,5.575534e-7,1.092493e-7,0.00008823041,0.9645852,0.0001605592],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005002557,0.9954522,0.000003647955,0.0004044719,0.0009762757,0.0004214117,0.00004612383,0.00002202477,0.002173602],"genre_scores_gemma":[0.00003440837,0.9961542,0.001174167,0.0001392159,0.0004432473,0.00001753755,0.0002150073,0.00003988964,0.001782288],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9235524,"threshold_uncertainty_score":0.7283802,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1946010634","doi":"10.1034/j.1399-0004.2003.00107.x","title":"Development of the thyroid gland: lessons from congenitally hypothyroid mice and men","year":2003,"lang":"en","type":"review","venue":"Clinical Genetics","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Thyroid; Congenital hypothyroidism; Endocrinology; Medicine; Internal medicine; Dysgenesis; PAX8; Ectopic thyroid; Follicular cell; Biology; Anatomy; Transcription factor; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.1320650139202368,"gpt":0.4130134858708299,"spread":0.2809484719505931,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002679886,0.0004075914,0.001834155,0.0000410646,0.00008310679,0.00001675839,0.0002572253,0.0004872784,0.00003226758],"category_scores_gemma":[0.0001675858,0.0002433339,0.00050861,0.0001432689,0.0002542525,0.000009194799,0.0002148732,0.0004160205,0.00004311461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004132125,"about_ca_system_score_gemma":0.0008744353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005590881,"about_ca_topic_score_gemma":0.00002728418,"domain_scores_codex":[0.9973108,0.0002190603,0.001402737,0.0005304424,0.0002839577,0.0002530557],"domain_scores_gemma":[0.998027,0.0004697453,0.0005369884,0.0006664633,0.00007699974,0.0002227777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002480071,0.0006097577,0.001071664,0.0008940953,0.001197093,0.00001228083,0.0001001627,4.7202e-8,0.000005672761,0.00001840684,0.001308831,0.9947572],"study_design_scores_gemma":[0.001913599,0.0002031319,0.002654843,0.001445686,0.003307134,0.00001935649,0.00005001282,0.000001109939,0.00001259684,0.00009552494,0.990041,0.0002560505],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005275638,0.9903234,0.00001335676,0.00005280928,0.0002744856,0.0009423859,0.0001457809,0.00001336813,0.002958759],"genre_scores_gemma":[0.0002656689,0.9904538,0.007654149,0.0001523629,0.0001011809,0.00003380524,0.0001186206,0.00006067101,0.001159714],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9945011,"threshold_uncertainty_score":0.9922869,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2891134498","doi":"10.1530/ec-18-0309","title":"Association between PCOS and autoimmune thyroid disease: a systematic review and meta-analysis","year":2018,"lang":"en","type":"review","venue":"Endocrine Connections","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Medicine; Meta-analysis; Systematic review; Autoimmune disease; MEDLINE; Disease; Graves' disease; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.06424997855928212,"gpt":0.3581950795294299,"spread":0.2939451009701478,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000294386,0.0005062452,0.007286977,0.0003943947,0.0002234799,0.00005811629,0.00008235414,0.00009253089,0.0003671945],"category_scores_gemma":[0.0008716303,0.000333533,0.002040701,0.0008789532,0.0000434821,0.00007489431,0.0000905952,0.000239387,0.00008227189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001705106,"about_ca_system_score_gemma":0.0001015845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000485388,"about_ca_topic_score_gemma":0.00002795563,"domain_scores_codex":[0.9975597,0.00035845,0.0009527692,0.0005718915,0.0002765289,0.0002806158],"domain_scores_gemma":[0.9976196,0.0005279992,0.0007461794,0.0006974706,0.0001559918,0.0002527029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.000001237942,0.00008927911,0.0001250331,0.5434147,0.4538346,0.00002014267,0.00000950722,1.682719e-8,8.177767e-9,0.00006517435,0.002059416,0.000380899],"study_design_scores_gemma":[0.0002544917,0.00006868822,0.0001547533,0.01075073,0.8394431,0.00004715217,0.000004976467,9.264232e-7,1.902957e-8,0.00002266727,0.1490448,0.0002077328],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000002125576,0.994292,0.00002865751,0.001229265,0.00003608925,0.003521081,0.0005733352,0.0000987155,0.000218746],"genre_scores_gemma":[0.00007717199,0.9827884,0.00005059531,0.0001571501,0.00006045191,0.001419734,0.000744243,0.00004630888,0.01465595],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5326639,"threshold_uncertainty_score":0.9999117,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2508313279","doi":"10.1210/jc.2016-1506","title":"Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus","year":2016,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Gestational diabetes; Medicine; Pregnancy; Obstetrics; Thyroid function; Incidence (geometry); Body mass index; Diabetes mellitus; Thyroid; Gestation; Endocrinology","retraction":null,"screen_n_in":null,"score":{"opus":0.02217787476987441,"gpt":0.3123666049308786,"spread":0.2901887301610042,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009443683,0.0001957878,0.001113008,0.0001655799,0.00004640666,0.000004800912,0.0002466821,0.0001327807,0.00004715229],"category_scores_gemma":[0.001667173,0.00008837321,0.0002402366,0.0001908771,0.0004772286,0.0001907072,0.00003520733,0.0005185881,0.000008941507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002111962,"about_ca_system_score_gemma":0.0002391638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009483912,"about_ca_topic_score_gemma":0.00002552459,"domain_scores_codex":[0.9967269,0.0009720726,0.001320509,0.0001814884,0.0004177384,0.0003813347],"domain_scores_gemma":[0.9957352,0.00197373,0.001373379,0.0003391975,0.0003843557,0.0001941972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006099129,0.004205295,0.9401197,0.000009798664,0.002545832,0.0002270888,0.0004635152,0.000005671371,0.003208156,0.0007262924,0.0001634429,0.04222612],"study_design_scores_gemma":[0.02070319,0.003327062,0.9686444,0.0002283844,0.001115468,0.00004519169,0.00004895556,0.000008166275,0.001990647,0.003711117,0.00008465693,0.00009272515],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851438,0.01322875,0.00004462493,0.001093818,0.00009683772,0.0002210841,0.00005042445,0.00001075538,0.0001099306],"genre_scores_gemma":[0.9856876,0.01347001,0.0003391416,0.0002776918,0.0001212729,0.000005476016,0.000003913574,0.00002204092,0.00007282708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04213339,"threshold_uncertainty_score":0.3603755,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2120705054","doi":"10.1210/jc.2005-1209","title":"Intellectual and Motor Development of Young Adults with Congenital Hypothyroidism Diagnosed by Neonatal Screening","year":2006,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital","funders":"","keywords":"Congenital hypothyroidism; Pediatrics; Intelligence quotient; Medicine; Cognition; Motor skill; Population; Balance (ability); Internal medicine; Physical therapy; Thyroid; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.01974938822243267,"gpt":0.2917407267217503,"spread":0.2719913384993176,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004303665,0.0002160881,0.000903518,0.0001099236,0.00009787147,0.00000790438,0.0001742194,0.00009826051,0.00004347258],"category_scores_gemma":[0.0005738942,0.0001201065,0.0001652474,0.0001051302,0.0005383255,0.00009094185,0.00007382086,0.0005283373,0.000005879805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009714819,"about_ca_system_score_gemma":0.0001649208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001073118,"about_ca_topic_score_gemma":0.00006654425,"domain_scores_codex":[0.9976662,0.0001930273,0.001302031,0.0001754599,0.0003403144,0.0003230088],"domain_scores_gemma":[0.9975651,0.001232533,0.0006390918,0.0001840236,0.0002266985,0.0001525411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.06640357,0.006007298,0.2691016,0.00008980855,0.009975347,0.002073637,0.01093269,0.00002627374,0.009942785,0.0007251552,0.01302863,0.6116932],"study_design_scores_gemma":[0.03697283,0.002639246,0.9220826,0.000102759,0.001682879,0.003293434,0.002332669,0.00003842632,0.006269729,0.0001710042,0.02413544,0.00027898],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751858,0.02203504,0.001692241,0.0004681865,0.000179078,0.0002417092,0.00001238511,0.00001132171,0.0001743087],"genre_scores_gemma":[0.99152,0.00178396,0.006037345,0.000152774,0.000233436,0.000004641746,0.000008315347,0.00002265997,0.0002368609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.652981,"threshold_uncertainty_score":0.4897802,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2067463727","doi":"10.1016/j.jpeds.2004.02.021","title":"Cognition and behavior at school entry in children with congenital hypothyroidism treated early with high-dose levothyroxine","year":2004,"lang":"en","type":"article","venue":"The Journal of Pediatrics","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Medicine; Levothyroxine; Congenital hypothyroidism; Pediatrics; Anxiety; Cognition; Internal medicine; Hormone; Thyroid; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.006165340312946315,"gpt":0.2107954433218215,"spread":0.2046301030088751,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118994,0.0001782411,0.0002669523,0.000186635,0.00008065692,0.0000200867,0.00006396318,0.0000664066,0.00001777388],"category_scores_gemma":[0.00002313162,0.00009480686,0.0000360815,0.0002444561,0.00008848779,0.0001572101,0.00002151832,0.0002815569,0.00001204996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001296371,"about_ca_system_score_gemma":0.0001407071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002718035,"about_ca_topic_score_gemma":0.0001255175,"domain_scores_codex":[0.9990407,0.000034995,0.0002685453,0.0001116648,0.0003432283,0.0002008727],"domain_scores_gemma":[0.999275,0.0000356749,0.0002426493,0.0001253345,0.0001263648,0.0001949753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002524209,0.0008393163,0.9946863,0.000007376658,0.0001047536,0.0003370884,0.0002488401,0.00002235851,0.000930329,0.000005942905,0.0000720358,0.0002214455],"study_design_scores_gemma":[0.02536481,0.003291783,0.9646697,0.00001922879,0.002920411,0.002640246,0.0001222658,2.104282e-7,0.0008069308,0.00004995795,0.000001241862,0.0001132129],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959077,0.003265426,0.00001584777,0.0002232635,0.00002311526,0.0004560646,0.00002367918,0.0000113984,0.00007348043],"genre_scores_gemma":[0.9978586,0.001446785,0.0002879213,0.00006080282,0.0001679527,0.000005744278,0.00001725999,0.00002726326,0.0001276328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0300166,"threshold_uncertainty_score":0.3866112,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2064815058","doi":"10.1080/10408440591007313","title":"Mode of Action: Developmental Thyroid Hormone Insufficiency—Neurological Abnormalities Resulting From Exposure to Propylthiouracil","year":2005,"lang":"en","type":"review","venue":"Critical Reviews in Toxicology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Health Canada; U.S. Environmental Protection Agency","keywords":"Propylthiouracil; Thyroid; Hormone; Medicine; Endocrinology; Internal medicine; Thyroid function; Antithyroid agent; Mode of action; Physiology; Graves' disease; Biology; Toxicology","retraction":null,"screen_n_in":null,"score":{"opus":0.1298748917620394,"gpt":0.4258648565760135,"spread":0.2959899648139741,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005065753,0.0006341033,0.003905397,0.0003073287,0.00008729424,0.00001818994,0.000331633,0.0007755971,0.0002427917],"category_scores_gemma":[0.003894372,0.0004514201,0.0005101314,0.0005184815,0.0003102003,0.00008960614,0.0002518605,0.00098124,0.0002718892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003274714,"about_ca_system_score_gemma":0.0005092327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002694589,"about_ca_topic_score_gemma":0.0000463832,"domain_scores_codex":[0.9951507,0.0007022487,0.002213652,0.0008814856,0.000346804,0.0007050353],"domain_scores_gemma":[0.9978639,0.0009353152,0.0002949497,0.0004658813,0.0001004168,0.0003394719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001641278,0.001971044,0.00007830394,0.004662806,0.00006631786,0.0002046088,0.0002254283,9.724066e-7,0.00004096305,0.0005016567,0.001459676,0.9906241],"study_design_scores_gemma":[0.0009455833,0.002889471,0.0002824979,0.005541427,0.0005587336,0.0003018135,0.00009577326,0.000007310249,0.000007745403,0.0001055482,0.9888638,0.0004002833],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002543271,0.9924738,0.00007183908,0.0006645049,0.0002131526,0.002293973,0.0001261952,0.00004490261,0.001568345],"genre_scores_gemma":[0.002872781,0.9862207,0.008649808,0.0009258848,0.0002339373,0.0007132271,0.0001391163,0.00004798869,0.000196541],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9902238,"threshold_uncertainty_score":0.9997938,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2145176955","doi":"10.1016/s0009-9120(02)00406-x","title":"Controversies in urinary iodine determinations","year":2002,"lang":"en","type":"review","venue":"Clinical Biochemistry","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Center for Research Resources","keywords":"Iodine; Iodine deficiency; Urinary system; Medicine; Pregnancy; Goiter; Population; Pediatrics; Physiology; Internal medicine; Endocrinology; Environmental health; Thyroid; Chemistry; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.1179473590813401,"gpt":0.4525693386165467,"spread":0.3346219795352066,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001248397,0.0003180525,0.001698833,0.00007109206,0.00002954286,0.00001168653,0.0001402025,0.0006573988,0.0002601081],"category_scores_gemma":[0.001328318,0.0002540058,0.0007981288,0.0001827108,0.0001630265,0.00001315174,0.00007951782,0.0005674268,0.0002466078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001163456,"about_ca_system_score_gemma":0.0001843591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000229267,"about_ca_topic_score_gemma":4.672537e-7,"domain_scores_codex":[0.998151,0.00004536855,0.0009132701,0.0005162212,0.0001359146,0.0002382131],"domain_scores_gemma":[0.9980822,0.0009262988,0.0002414799,0.0005275863,0.00003442652,0.0001879783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002788472,0.002336689,0.0009417796,0.006721123,0.0002552064,0.0007774717,0.000003724884,5.387101e-9,6.511905e-7,0.000004379759,0.01157435,0.9773567],"study_design_scores_gemma":[0.002354415,0.0002271723,0.0001171558,0.005919908,0.001109317,0.000177555,0.000009168485,0.000002223543,0.000003394675,0.00001334545,0.9898359,0.0002304954],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004184321,0.9912685,3.953299e-7,0.0001493327,0.0001308219,0.0004109422,0.00008082508,0.00002942571,0.007511306],"genre_scores_gemma":[0.0006815313,0.9921959,0.00009565307,0.0001681945,0.0002364054,0.00006535459,0.0003087713,0.00003070817,0.006217506],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9782615,"threshold_uncertainty_score":0.9999912,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2063569860","doi":"10.1016/s0828-282x(09)70512-4","title":"Amiodarone-induced thyrotoxicosis: A review","year":2009,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false},"ca_institutions":"Queen's University; University of Toronto","funders":"","keywords":"Medicine; Amiodarone; Subacute thyroiditis; Goiter; Prednisone; Thyroid; Thyroiditis; Graves' disease; Thyroid disease; Internal medicine; Atrial fibrillation","retraction":null,"screen_n_in":null,"score":{"opus":0.05976371839434685,"gpt":0.3475121519791163,"spread":0.2877484335847695,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000368947,0.0004210808,0.004888907,0.00055463,0.00006443463,0.00001364532,0.0002724844,0.0004476394,0.00004483506],"category_scores_gemma":[0.0002615596,0.0002955211,0.001904382,0.0002944364,0.00006754686,0.00004195513,0.000008717419,0.0007682622,0.00009741683],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004935508,"about_ca_system_score_gemma":0.006447064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001428618,"about_ca_topic_score_gemma":0.0001989166,"domain_scores_codex":[0.9977821,0.0002992423,0.001024734,0.0002414994,0.0001638443,0.0004886274],"domain_scores_gemma":[0.9974769,0.00005352226,0.0006920982,0.0004516559,0.0002127847,0.001113016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005162684,0.000004255352,0.00002215025,0.005633031,0.001120444,0.002078456,0.000005053002,1.996936e-7,1.155009e-7,0.00002679055,0.05856425,0.9325401],"study_design_scores_gemma":[0.0005624579,0.0007024332,0.00007002529,0.0455124,0.00633843,0.01062471,0.000004592602,1.460762e-8,1.037452e-7,0.00003923899,0.9359557,0.0001899164],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003453778,0.9879056,0.00001369726,0.0005475086,0.0004795815,0.0008820792,0.00003456086,0.000006395511,0.01012714],"genre_scores_gemma":[0.0002039862,0.9975488,0.00005393874,0.0008949463,0.0009935352,0.00002438518,0.00004560369,0.00004598794,0.0001888322],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9323502,"threshold_uncertainty_score":0.9999497,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}