{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":464,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":464,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"be92a5f4748d","filters":{"topic":"Tuberous Sclerosis Complex Research"}},"results":[{"id":"W2147028601","doi":"10.1056/nejmoa1100391","title":"Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis","year":2011,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":1115,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"NHLBI Division of Intramural Research; National Center for Research Resources; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Cincinnati Children's Hospital Medical Center; National Institutes of Health; U.S. Food and Drug Administration; Tuberous Sclerosis Alliance; LAM Foundation; Pfizer","keywords":"Lymphangioleiomyomatosis; Sirolimus; Medicine; Placebo; Lung; Urology; Internal medicine; Vital capacity; Discontinuation; Gastroenterology; Diffusing capacity; Lung function; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.07152300693686296,"gpt":0.3049537802859522,"spread":0.2334307733490892,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001144334,0.0001195172,0.0006409072,0.0004841693,0.00001759126,0.000002005134,0.0001248266,0.00005989571,0.0003466752],"category_scores_gemma":[0.0005902413,0.00007725219,0.00005096196,0.0003012431,0.0002003995,0.00006027039,0.00003894381,0.000227955,0.000002073175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000455097,"about_ca_system_score_gemma":0.000143756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003082274,"about_ca_topic_score_gemma":0.00002886493,"domain_scores_codex":[0.9983649,0.0001020317,0.0007013372,0.0001117939,0.0005016803,0.0002182364],"domain_scores_gemma":[0.9987575,0.0003081759,0.0002330242,0.0001755017,0.0001691381,0.0003566529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01954868,0.0007226731,0.4333956,0.0003242547,0.0003522753,0.0008260204,0.01347107,0.000007026426,0.06830937,0.0006946793,0.002472489,0.4598759],"study_design_scores_gemma":[0.1131609,0.003354491,0.8741375,0.001514699,0.0001368276,0.002151497,0.0002453824,0.00003193594,0.002303496,0.0003589009,0.002526677,0.00007775029],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914331,0.002390704,0.0001547872,0.002314333,0.0001154461,0.0001666736,8.272098e-7,0.00000598311,0.00341811],"genre_scores_gemma":[0.996934,0.0009503764,0.001190633,0.0001896783,0.0006420516,5.441526e-7,0.000001002281,0.00001495722,0.00007676314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4597981,"threshold_uncertainty_score":0.379585,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3186573778","doi":"10.1016/j.pediatrneurol.2021.07.011","title":"Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations","year":2021,"lang":"en","type":"article","venue":"Pediatric Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":705,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Tuberous Sclerosis Association; Upsher-Smith; H. Lundbeck A/S; LivaNova; Depomed; Amneal Pharmaceuticals; Mallinckrodt Pharmaceuticals; Greenwich Biosciences; Tuberous Sclerosis Alliance","keywords":"Tuberous sclerosis; TSC1; Medicine; Presentation (obstetrics); Genetic testing; Pediatrics; Pathology; Surgery; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.05552967818157058,"gpt":0.3193548388332552,"spread":0.2638251606516847,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001837005,0.0001443375,0.000257648,0.0002061372,0.0001284335,0.00006048791,0.0001044165,0.00006678752,0.001001135],"category_scores_gemma":[0.0003295848,0.0001535025,0.00003108641,0.0003200959,0.0001009263,0.00006068169,0.0004177169,0.0002290077,0.0000356434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000197329,"about_ca_system_score_gemma":0.00002851158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000389306,"about_ca_topic_score_gemma":0.0000637706,"domain_scores_codex":[0.9984952,0.0002021607,0.0002779357,0.0005028356,0.0002076749,0.0003142389],"domain_scores_gemma":[0.9987529,0.0005953931,0.0000531562,0.0002702972,0.0001593841,0.0001688775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001395769,0.0002663298,0.9283656,0.0001108108,0.00009727864,0.0003994759,0.00005213828,0.000003333252,0.001583459,0.0004789786,0.05586173,0.0126413],"study_design_scores_gemma":[0.001542022,0.0001672993,0.9831434,0.000004804554,0.00005367309,0.0006393159,0.0000125731,0.0005793114,0.00001952884,0.0001153443,0.01360908,0.0001136874],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9540468,0.0005523474,0.0001030833,0.04343125,0.0003937831,0.0002858278,0.00005876656,0.00007461165,0.0010535],"genre_scores_gemma":[0.9846031,0.01007838,0.001292658,0.003196513,0.0003002879,0.00004735933,0.0002765064,0.00002555719,0.0001796335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05477777,"threshold_uncertainty_score":0.9999121,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2023259349","doi":"10.1097/pas.0000000000000248","title":"Tuberous Sclerosis–associated Renal Cell Carcinoma","year":2014,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":294,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Tuberous sclerosis; Pathology; Clear cell; Renal cell carcinoma; Angiomyolipoma; Eosinophilic; Chromophobe cell; Medicine; Clear cell carcinoma; Nephrectomy; Kidney; Carcinoma; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03493008061522505,"gpt":0.2782705947200807,"spread":0.2433405141048557,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002210306,0.0002044976,0.0009617781,0.0002033328,0.000145462,0.00002373973,0.0004698144,0.00007268405,0.0001719801],"category_scores_gemma":[0.0003190763,0.0001238994,0.0003460068,0.0005560217,0.001292359,0.00005205882,0.0001389555,0.001013691,0.00008829153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001268256,"about_ca_system_score_gemma":0.0001331455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005293185,"about_ca_topic_score_gemma":0.000003875547,"domain_scores_codex":[0.9964973,0.001303636,0.0006823022,0.0002306674,0.0006754596,0.0006106485],"domain_scores_gemma":[0.9970704,0.001019118,0.000672056,0.0004575348,0.0004127514,0.0003681004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01124971,0.003555017,0.2363822,0.00007357386,0.0004986301,0.008987224,0.002298559,0.000373665,0.4632137,0.00118762,0.01758102,0.254599],"study_design_scores_gemma":[0.006672344,0.01270995,0.9489555,0.0001136972,0.000258976,0.01949667,0.0003406993,0.0003202921,0.004763802,0.0004656265,0.005597004,0.0003054211],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910166,0.0002654792,0.000211873,0.005969659,0.0001269835,0.0001243732,0.00000365049,0.00002435778,0.002257056],"genre_scores_gemma":[0.9977727,0.00009676284,0.0004832293,0.0009295315,0.0004414675,0.000003813459,0.000002587555,0.00003711047,0.000232825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7125733,"threshold_uncertainty_score":0.505247,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029073739","doi":"10.1097/pas.0b013e3181d90370","title":"Renal Epithelioid Angiomyolipoma With Atypia: A Series of 40 Cases With Emphasis on Clinicopathologic Prognostic Indicators of Malignancy","year":2010,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":253,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Nuclear atypia; Atypia; Epithelioid cell; Malignancy; Pathology; Giant cell; Angiomyolipoma; Medicine; Biology; Immunohistochemistry; Kidney; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02620115657007056,"gpt":0.3064147578424091,"spread":0.2802136012723385,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001282892,0.0002507061,0.001288132,0.0005128986,0.00007764743,0.000007968671,0.0004152731,0.00008500971,0.0001182214],"category_scores_gemma":[0.0004236768,0.0001206309,0.0002250521,0.001057592,0.00464595,0.00006754738,0.00008567409,0.0009813544,0.000006271181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000023664,"about_ca_system_score_gemma":0.0003509645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002179022,"about_ca_topic_score_gemma":0.0000188184,"domain_scores_codex":[0.9971364,0.0006028435,0.0008560495,0.0002654563,0.0007000598,0.0004392441],"domain_scores_gemma":[0.9957929,0.001421216,0.001533132,0.0005484543,0.0004638636,0.0002404586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06251629,0.001956912,0.8113142,0.00009115267,0.0004269101,0.02820234,0.001041749,0.0000429349,0.04988698,0.0009013098,0.00009810048,0.04352114],"study_design_scores_gemma":[0.002991903,0.05412155,0.8278775,0.0004277891,0.0003154787,0.1017642,0.0006237034,0.00000250824,0.01137877,0.00009136731,0.0002298386,0.0001754072],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974552,0.0001666816,0.00004562982,0.001736103,0.00005073658,0.000307751,0.00002679692,0.00001537208,0.0001956687],"genre_scores_gemma":[0.9965283,0.0001933812,0.002931097,0.0001240588,0.0001384203,0.00001214169,0.000002541428,0.00003555281,0.00003456576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07356184,"threshold_uncertainty_score":0.9980628,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2054347313","doi":"10.1111/j.1528-1157.2000.tb00327.x","title":"Epilepsy Surgery in Children with Tuberous Sclerosis Complex: Presurgical Evaluation and Outcome","year":2000,"lang":"en","type":"article","venue":"Epilepsia","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":218,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Tuberous sclerosis; Ictal; Epilepsy surgery; Magnetic resonance imaging; Epilepsy; Electrocorticography; Medicine; Ictal-Interictal SPECT Analysis by SPM; Electroencephalography; Nuclear medicine; Radiology; Surgery","retraction":null,"screen_n_in":null,"score":{"opus":0.108691427883169,"gpt":0.3321023250145224,"spread":0.2234108971313534,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001543029,0.0002936242,0.00071082,0.0003158807,0.0001263074,0.00007067644,0.0001390109,0.0001481458,0.005013032],"category_scores_gemma":[0.0001904307,0.0002405704,0.0001035523,0.000596904,0.0002808782,0.0001798211,0.00005983279,0.000478735,0.0002248163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001868612,"about_ca_system_score_gemma":0.0001385787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005557081,"about_ca_topic_score_gemma":0.00009438872,"domain_scores_codex":[0.9965484,0.0003891047,0.0006202994,0.0006619797,0.001114667,0.0006656157],"domain_scores_gemma":[0.9985117,0.0003574986,0.00007057527,0.0005853187,0.0001369921,0.0003379498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004190901,0.0002640127,0.9165849,0.00002215854,0.00006393637,0.00001522117,0.00009326042,0.00007592473,0.0002876798,0.0000420627,0.001534265,0.08059748],"study_design_scores_gemma":[0.003229006,0.0002438894,0.9921209,0.0001604951,0.00008250949,0.0004578592,0.00001615993,0.002851654,0.00005873437,0.00004383273,0.0004765484,0.0002584731],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939488,0.0003625267,0.0000129049,0.001337426,0.00002703314,0.001438037,0.00001813016,0.0001084362,0.002746744],"genre_scores_gemma":[0.9979019,0.0001528183,0.0007255896,0.0004068074,0.000129105,0.0001636074,0.0001445768,0.00005767494,0.0003179264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08033901,"threshold_uncertainty_score":0.9958965,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2170119537","doi":"10.1016/j.pediatrneurol.2013.08.017","title":"Subependymal Giant Cell Astrocytoma: Diagnosis, Screening, and Treatment. Recommendations From the International Tuberous Sclerosis Complex Consensus Conference 2012","year":2013,"lang":"en","type":"article","venue":"Pediatric Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":211,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Tuberous sclerosis; Subependymal giant cell astrocytoma; Subependymal zone; Giant cell; Medicine; Pathology; Hydrocephalus; Astrocytoma; Radiology; Cancer research; Glioma","retraction":null,"screen_n_in":null,"score":{"opus":0.1003099853723124,"gpt":0.2906461267230273,"spread":0.1903361413507149,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001520832,0.0002890786,0.0003920516,0.000165763,0.0003000008,0.0001284431,0.0003546638,0.0001353562,0.007279784],"category_scores_gemma":[0.0001592572,0.0002169471,0.0001027318,0.000204317,0.0002666627,0.0001140731,0.0003134916,0.0004626871,0.0004809267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004888215,"about_ca_system_score_gemma":0.0001107963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003946357,"about_ca_topic_score_gemma":0.0007844916,"domain_scores_codex":[0.9977399,0.0002930026,0.0004328309,0.0006114577,0.0003559974,0.000566807],"domain_scores_gemma":[0.9969098,0.001911888,0.0001600567,0.0004793122,0.0002402895,0.0002986686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003670868,0.0006465887,0.7207257,0.000009572494,0.000133149,0.0000572045,0.0002244806,0.000005592549,0.004866474,0.00008445956,0.2472996,0.02558012],"study_design_scores_gemma":[0.003734084,0.001232467,0.9775668,0.000005668656,0.0001931448,0.0001980486,0.00006885769,0.001708528,0.0002953646,0.00007505548,0.01473486,0.0001871027],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9164923,0.0005772408,0.0001163351,0.08065593,0.0002971302,0.0008418282,0.0002469915,0.00009223569,0.0006799718],"genre_scores_gemma":[0.9913746,0.001733465,0.002301416,0.002809526,0.0007876662,0.0003634236,0.0002431708,0.0000401115,0.0003466742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2568411,"threshold_uncertainty_score":0.9936277,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2074883911","doi":"10.1371/journal.pone.0023379","title":"Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"York University; National Cancer Institute; Cincinnati Children's Hospital Medical Center; Biogen; Loma Linda University; Brigham and Women's Hospital; Pfizer","keywords":"Tuberous sclerosis; Medicine; Sirolimus; Angiomyolipoma; Gastroenterology; Renal function; Internal medicine; TSC1; Everolimus; Urology; Kidney; Pathology; PI3K/AKT/mTOR pathway","retraction":null,"screen_n_in":null,"score":{"opus":0.2899315814485079,"gpt":0.3299360887373072,"spread":0.04000450728879934,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003814109,0.0002408976,0.0006580511,0.0002173245,0.00008717882,0.00002480833,0.0001365864,0.0001119816,0.0002435841],"category_scores_gemma":[0.001087982,0.00021066,0.0001169187,0.0001444278,0.0003278425,0.0001054287,0.0001146017,0.0001656349,0.00000776586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003661414,"about_ca_system_score_gemma":0.0001193928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002648073,"about_ca_topic_score_gemma":0.0000140269,"domain_scores_codex":[0.9980499,0.00009269432,0.000454805,0.0004530622,0.0004761943,0.000473343],"domain_scores_gemma":[0.9981633,0.0001852071,0.0001403309,0.0004787032,0.0002292471,0.0008032287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.214791,0.03217168,0.02482749,0.002758715,0.002533545,0.00006047398,0.003922414,6.563882e-8,0.7074981,0.0003234959,0.001097655,0.01001541],"study_design_scores_gemma":[0.4755532,0.01756851,0.05814379,0.00539982,0.002515456,0.00007817252,0.0003822254,0.001626091,0.4372359,0.0003164542,0.0003564465,0.0008239959],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959872,0.0005289416,0.00004199755,0.0002920442,0.00003321958,0.002413965,0.0002634414,0.00006015235,0.0003790524],"genre_scores_gemma":[0.9906918,0.00004083685,0.007913612,0.0006098623,0.0001950901,0.0002462517,0.00001458167,0.00007564949,0.0002123233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2702622,"threshold_uncertainty_score":0.8590466,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2161179722","doi":"10.1067/s0022-3476(03)00494-3","title":"Fetal rhabdomyoma: prenatal diagnosis, clinical outcome, and incidence of associated tuberous sclerosis complex","year":2003,"lang":"en","type":"article","venue":"The Journal of Pediatrics","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":200,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Tuberous sclerosis; Medicine; Rhabdomyoma; Incidence (geometry); Fetal echocardiography; Heart disease; Pediatrics; Pregnancy; Prenatal diagnosis; Fetus; Gestational age; Obstetrics; Internal medicine; Cardiology; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.1389729702487261,"gpt":0.3746972511906212,"spread":0.2357242809418952,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.005534419,0.0002108909,0.0008600599,0.0002529759,0.0001461369,0.00003111756,0.0004000295,0.0001710353,0.0001029466],"category_scores_gemma":[0.008640311,0.0001407903,0.0002711925,0.0006711892,0.0004444657,0.0001638783,0.0001795095,0.001028987,0.00001035608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001218042,"about_ca_system_score_gemma":0.0003162127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005675952,"about_ca_topic_score_gemma":0.00003419153,"domain_scores_codex":[0.995639,0.0008612461,0.001654088,0.0001778443,0.001253683,0.0004141884],"domain_scores_gemma":[0.9941917,0.003198959,0.001025548,0.0003801685,0.0008463212,0.0003572677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002191022,0.0005946099,0.9912345,0.0001233167,0.00006630562,0.00003248491,0.0001608941,0.00001391092,0.0003857117,0.00006574608,0.004494469,0.002608899],"study_design_scores_gemma":[0.003349826,0.001430836,0.9929073,0.0001000052,0.0006852103,0.000611711,0.0001836452,0.00004995622,0.0003076465,0.0001030771,0.0001328923,0.0001378231],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953153,0.002880578,0.000195489,0.0007966797,0.0002693672,0.0003187257,0.00002362795,0.00001476607,0.0001855051],"genre_scores_gemma":[0.9936149,0.003931822,0.001832986,0.0002113641,0.0003155785,0.000002918152,0.000002597997,0.00003170468,0.00005609507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004361576,"threshold_uncertainty_score":0.9997103,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2146421823","doi":"10.1016/s2213-2600(13)70090-0","title":"Serum VEGF-D concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial","year":2013,"lang":"en","type":"article","venue":"The Lancet Respiratory Medicine","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":199,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Lymphangioleiomyomatosis; Medicine; Sirolimus; Lymphangiomatosis; Tuberous sclerosis; Internal medicine; Gastroenterology; Placebo; Multicenter trial; Biomarker; Pathology; Randomized controlled trial; Multicenter study; Lymphatic system","retraction":null,"screen_n_in":null,"score":{"opus":0.06807586067225029,"gpt":0.3500328225927133,"spread":0.281956961920463,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001215207,0.0002636988,0.001171484,0.0003646477,0.00009037697,0.00001249749,0.0004023364,0.0001104759,0.0004432104],"category_scores_gemma":[0.001029967,0.0001384045,0.0003204711,0.001256662,0.001057426,0.00008928964,0.0001650221,0.00009157429,0.000004820232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002750961,"about_ca_system_score_gemma":0.0002270895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007710767,"about_ca_topic_score_gemma":0.00004581863,"domain_scores_codex":[0.9967251,0.0007618431,0.0008616699,0.0003716933,0.0009396524,0.000340015],"domain_scores_gemma":[0.996824,0.0009923163,0.0005808289,0.0009325606,0.0005342834,0.0001359931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.08547287,0.001279818,0.5188476,0.0001655048,0.007198948,0.000006643038,0.005694096,0.00001935653,0.3734475,0.0002494421,0.000785578,0.006832627],"study_design_scores_gemma":[0.04836219,0.001319421,0.9190329,0.0003370605,0.00149203,0.000008039671,0.0004457961,0.001820541,0.02672026,0.00002319706,0.000337693,0.0001008821],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915583,0.0005976944,0.00001390869,0.004649232,0.0001495249,0.002384592,0.00007694146,0.00002685118,0.0005429885],"genre_scores_gemma":[0.9987063,0.0001093014,0.00004868606,0.0006208646,0.0002319023,0.0001848947,0.0000131314,0.00002234871,0.00006255211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4001853,"threshold_uncertainty_score":0.5643973,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2413544455","doi":"10.1097/pas.0000000000000508","title":"Eosinophilic, Solid, and Cystic Renal Cell Carcinoma","year":2015,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":190,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Calgary Laboratory Services; Rockyview General Hospital; University of Calgary","funders":"European Regional Development Fund; Calgary Laboratory Services; Univerzita Karlova v Praze","keywords":"Renal cell carcinoma; Medicine; Pathology; Eosinophilic; Carcinoma","retraction":null,"screen_n_in":null,"score":{"opus":0.04848766062175659,"gpt":0.3168528143632159,"spread":0.2683651537414594,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001318989,0.0001329036,0.0006394491,0.0001495534,0.00006088612,0.00001604754,0.0002230803,0.00003818745,0.00003868148],"category_scores_gemma":[0.0001603283,0.00007679029,0.0001105776,0.0002584189,0.001367402,0.00004295836,0.0001324894,0.0006097194,0.00003307645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006459777,"about_ca_system_score_gemma":0.0001952075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002605939,"about_ca_topic_score_gemma":0.000001082561,"domain_scores_codex":[0.9980468,0.0005645132,0.0004200306,0.0001582224,0.0004464247,0.0003639726],"domain_scores_gemma":[0.9981365,0.0004621874,0.0003241998,0.0002744113,0.0003092367,0.0004934881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.03633051,0.002669577,0.2671088,0.0001651399,0.0004299896,0.09400722,0.009753997,0.0004871536,0.3786337,0.001544344,0.02245924,0.1864103],"study_design_scores_gemma":[0.01413024,0.03076368,0.684338,0.0001135456,0.0004597918,0.2445763,0.002997611,0.0006902473,0.004678383,0.002574412,0.01418161,0.0004961618],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905654,0.000978208,0.0001088885,0.006921823,0.0000791312,0.00009640474,0.000002475534,0.000009260578,0.001238364],"genre_scores_gemma":[0.9981411,0.0001160666,0.0007408699,0.0004489276,0.000378952,0.000001951536,8.045353e-7,0.00001877267,0.0001525208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4172292,"threshold_uncertainty_score":0.5038249,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2020209656","doi":"10.1073/pnas.1106454108","title":"Regulable neural progenitor-specific <i>Tsc1</i> loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":179,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; University of California, Los Angeles; National Institutes of Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Tuberous Sclerosis Alliance","keywords":"TSC1; Tuberous sclerosis; Giant cell; TSC2; Biology; Cortical dysplasia; Nestin; Epilepsy; Neural stem cell; Pathology; Epileptogenesis; Progenitor cell; Cell biology; Neuroscience; Stem cell; PI3K/AKT/mTOR pathway; Genetics; Medicine; Signal transduction","retraction":null,"screen_n_in":null,"score":{"opus":0.1778198010905996,"gpt":0.2884772856417605,"spread":0.1106574845511608,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001144271,0.000156137,0.0003503062,0.0003386203,0.0001298961,0.00001633466,0.0006758738,0.0001161546,0.00004952034],"category_scores_gemma":[0.0001033148,0.0001022051,0.00008063491,0.001557849,0.001534245,0.0004347315,0.0001701674,0.0003105577,0.00000196392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008807987,"about_ca_system_score_gemma":0.00009847618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005965691,"about_ca_topic_score_gemma":9.036786e-7,"domain_scores_codex":[0.996799,0.0000131428,0.0005359796,0.0003774828,0.001959646,0.0003147779],"domain_scores_gemma":[0.998691,0.00006820301,0.000394471,0.00003093421,0.0007366636,0.0000787077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002994305,0.000279266,0.01838866,0.0001682492,0.0000194507,4.530894e-8,0.0005153136,0.0009261709,0.9755526,0.003094374,0.0004971092,0.0002593679],"study_design_scores_gemma":[0.0008954872,0.0003988379,0.1351188,0.0003368268,0.00002317715,0.00003977225,0.0002913536,0.02483547,0.8351201,0.002812479,0.000009703201,0.000117928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958878,0.00008744028,0.00001311719,0.001073169,0.0000130865,0.0005521621,0.00001541241,0.00001632626,0.002341501],"genre_scores_gemma":[0.9926863,0.0000432322,0.006963667,0.0001235275,0.0000404832,0.00001982124,3.055705e-7,0.00001340166,0.000109202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1404324,"threshold_uncertainty_score":0.5652989,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2003025495","doi":"10.1016/j.pedhc.2006.05.004","title":"Tuberous Sclerosis Complex: A Review","year":2007,"lang":"en","type":"review","venue":"Journal of Pediatric Health Care","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":168,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Tuberous sclerosis; TSC2; TSC1; Penetrance; Expressivity; Hamartoma; Gastrointestinal tract; Medicine; Pathology; Organ system; Biology; Genetics; Phenotype; Gene; Disease; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.3581088150752837,"gpt":0.5009175766824095,"spread":0.1428087616071259,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003814154,0.000753363,0.007165703,0.001714198,0.0002136628,0.0000486145,0.0007951673,0.0004796927,0.0004652283],"category_scores_gemma":[0.0009628888,0.0005581617,0.002366626,0.002503822,0.00008610365,0.0001098514,0.0002077404,0.003214027,0.0002572263],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002910963,"about_ca_system_score_gemma":0.01039924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006491025,"about_ca_topic_score_gemma":0.00001442432,"domain_scores_codex":[0.9901583,0.0008518809,0.004633241,0.0005283769,0.002553415,0.001274756],"domain_scores_gemma":[0.9911144,0.000722983,0.003477345,0.0009296347,0.001966185,0.00178944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001415674,0.00008720226,0.00002916976,0.2420417,0.000108317,0.0001485323,0.00006149607,4.097984e-8,3.147847e-8,0.000002684205,0.163323,0.5941836],"study_design_scores_gemma":[0.0007855063,0.001257549,0.0002735492,0.1033301,0.002752953,0.003633501,0.00004942216,1.038066e-7,2.700694e-8,8.789511e-7,0.8876048,0.0003115773],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000007070256,0.994732,0.0000395085,0.001444786,0.000686825,0.002523755,0.0001083368,0.00004579835,0.0004119473],"genre_scores_gemma":[0.000005915657,0.9863635,0.002647888,0.003825703,0.006727186,0.00002852017,0.0001263491,0.0001832524,0.00009165587],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7242818,"threshold_uncertainty_score":0.999687,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1978047708","doi":"10.1038/modpathol.3880360","title":"Primary Extrapulmonary Sugar Tumor (PEST): A Report of Four Cases","year":2001,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":162,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; Credit Valley Hospital","funders":"","keywords":"Pathology; Biology; Eosinophilic; Angiomyolipoma; Epithelioid cell; Mitosis; S100 protein; Immunohistochemistry; Medicine; Kidney; Cell biology; Endocrinology","retraction":null,"screen_n_in":null,"score":{"opus":0.08780094082898593,"gpt":0.3206777929784188,"spread":0.2328768521494328,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004578002,0.0001789931,0.0005547784,0.0002202872,0.00006068105,0.000005772995,0.0001677767,0.0001159663,0.0002731109],"category_scores_gemma":[0.00031756,0.0001630117,0.0001405434,0.0002105366,0.0002802018,0.00005835217,0.0001614764,0.0003036994,0.00005616209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008661047,"about_ca_system_score_gemma":0.0002135203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009428473,"about_ca_topic_score_gemma":0.00003662881,"domain_scores_codex":[0.997954,0.0001369829,0.0005063802,0.0004939353,0.000415418,0.000493267],"domain_scores_gemma":[0.998471,0.000168996,0.0001446709,0.0008479117,0.0001973665,0.000170008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.0008011193,0.0007778833,0.2540157,0.0002082149,0.00005278064,0.3908947,0.0002771511,0.00002346561,0.3297614,0.000097999,0.001704437,0.0213851],"study_design_scores_gemma":[0.001163154,0.0007877265,0.6034256,0.00008032367,0.00005993577,0.3887213,0.00004033956,0.0010211,0.00136857,0.0009624177,0.002190011,0.0001794655],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872246,0.000749262,0.001792358,0.001084291,0.00009480954,0.0004042721,0.00001284295,0.00009996967,0.008537571],"genre_scores_gemma":[0.993284,0.00006936287,0.003140641,0.0005774046,0.0001346174,0.00005124869,0.00004601024,0.00004698895,0.002649714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3494099,"threshold_uncertainty_score":0.6647426,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2743390842","doi":"10.1097/pas.0000000000000838","title":"Eosinophilic Solid and Cystic Renal Cell Carcinoma (ESC RCC)","year":2017,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Tuberous sclerosis; Renal cell carcinoma; Eosinophilic; Pathology; Medicine; Clear cell; Karyotype; Nephrectomy; Kidney; Internal medicine; Biology; Chromosome; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03823709343792856,"gpt":0.3247282274791154,"spread":0.2864911340411868,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001096758,0.0001585188,0.0007475889,0.0001324281,0.0003413585,0.00005421504,0.0005046638,0.00004694625,0.0000811956],"category_scores_gemma":[0.0002290572,0.00009376143,0.0001616613,0.00009293072,0.002634822,0.00007349816,0.0002511657,0.00075125,0.00003064246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004652481,"about_ca_system_score_gemma":0.0001239043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004720237,"about_ca_topic_score_gemma":0.000002600024,"domain_scores_codex":[0.998121,0.0004084492,0.0004401433,0.0002005548,0.0003966614,0.0004332059],"domain_scores_gemma":[0.9976518,0.000472125,0.0006845169,0.0006444971,0.0002124232,0.0003346791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01250553,0.001177418,0.2909151,0.0001365319,0.0002839733,0.0537755,0.00214167,0.00005579245,0.4676018,0.0008065791,0.003287958,0.1673121],"study_design_scores_gemma":[0.003007435,0.005034461,0.9472016,0.00005716135,0.0001447059,0.03985453,0.0002138809,0.0001251774,0.001928174,0.000494638,0.001792657,0.0001455721],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880432,0.0005788561,0.00005507532,0.00953878,0.0001005487,0.0001118749,0.000003804228,0.000007891991,0.001559987],"genre_scores_gemma":[0.9982549,0.0002801629,0.0004494689,0.0003153335,0.0004645056,0.000002398134,6.180462e-7,0.00002221006,0.0002103924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6562865,"threshold_uncertainty_score":0.9708112,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2116515545","doi":"10.1164/rccm.201305-0892oc","title":"Club Cell Protein 16 and Disease Progression in Chronic Obstructive Pulmonary Disease","year":2013,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Medicine; Pulmonary disease; Disease; Intensive care medicine; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02273417012980528,"gpt":0.3300431332208105,"spread":0.3073089630910052,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003152966,0.0002060954,0.0005485642,0.0002835875,0.00009208665,0.00002354699,0.0001120486,0.00003786657,0.0001757961],"category_scores_gemma":[0.001273819,0.0001405164,0.00006231421,0.0002972065,0.002307608,0.00021246,0.00008818778,0.0006183764,0.000003527017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002668085,"about_ca_system_score_gemma":0.0005493354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004464283,"about_ca_topic_score_gemma":0.000003302478,"domain_scores_codex":[0.9977974,0.0003071019,0.0005009194,0.0003029089,0.000693175,0.0003985545],"domain_scores_gemma":[0.9969046,0.0002568088,0.0001284738,0.0002269058,0.0005084712,0.001974728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002972866,0.0003926924,0.3730803,0.002164543,0.00002845228,0.002978315,0.0007631439,0.000001591681,0.04084741,0.000496125,0.0004280748,0.5758465],"study_design_scores_gemma":[0.002677988,0.008447347,0.9760613,0.002899404,0.0001747672,0.0001357756,0.006203391,0.00008302653,0.0004585334,0.001089703,0.001521486,0.0002472984],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660102,0.02576554,0.00004994677,0.007229017,0.00004305448,0.0005823569,0.00000519168,0.0000116409,0.0003030827],"genre_scores_gemma":[0.9981813,0.00008720682,0.0002016758,0.000989634,0.0004367694,0.00005389922,0.000002466298,0.00002519418,0.00002181733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.602981,"threshold_uncertainty_score":0.8502479,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2259186924","doi":"10.1016/j.eururo.2016.01.048","title":"Natural History of Renal Angiomyolipoma (AML): Most Patients with Large AMLs &gt;4 cm Can Be Offered Active Surveillance as an Initial Management Strategy","year":2016,"lang":"en","type":"article","venue":"European Urology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Natural history; Angiomyolipoma; Urology; Management strategy; Watchful waiting; Radiology; Kidney; Internal medicine; Cancer","retraction":null,"screen_n_in":null,"score":{"opus":0.02730242014387337,"gpt":0.2665111946564092,"spread":0.2392087745125358,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003434054,0.0002501593,0.0003954238,0.0002403073,0.00005432469,0.000007418922,0.0003437446,0.00005776267,0.0005376104],"category_scores_gemma":[0.00009770785,0.0001735452,0.00006145932,0.0001661201,0.0004064829,0.0001018386,0.0002267568,0.000269975,0.00007364211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003061961,"about_ca_system_score_gemma":0.0001659494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009268649,"about_ca_topic_score_gemma":0.0003582576,"domain_scores_codex":[0.9970862,0.0008781854,0.0003377438,0.0005524871,0.0005092882,0.0006360544],"domain_scores_gemma":[0.9984856,0.000115945,0.0001820453,0.000658196,0.0003218669,0.0002363485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.07927255,0.01003017,0.3581932,0.0005528423,0.004860644,0.008198113,0.008174965,0.00004122653,0.1952934,0.01538276,0.08666084,0.2333393],"study_design_scores_gemma":[0.007691911,0.004436784,0.9709547,0.00003440777,0.00004900983,0.00004064619,0.00003995707,0.00002447189,0.0003600364,0.00001923772,0.01612386,0.000225039],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761121,0.000081206,0.00005245327,0.0006612809,0.0002069273,0.0005202322,0.0001546872,0.00007623216,0.02213492],"genre_scores_gemma":[0.9954477,0.00001115534,0.00008249639,0.0009259468,0.0001470572,0.00001019702,0.0001884823,0.00007599944,0.003110999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6127614,"threshold_uncertainty_score":0.7076969,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1925039450","doi":"10.5858/2006-130-1219-mnopec","title":"Malignant Neoplasm of Perivascular Epithelioid Cells of the Liver","year":2006,"lang":"en","type":"article","venue":"Archives of Pathology & Laboratory Medicine","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"London Health Sciences Centre","funders":"","keywords":"Angiomyolipoma; Lymphangioleiomyomatosis; Perivascular Epithelioid Cell; Pathology; Epithelioid cell; Tuberous sclerosis; Clear cell; Immunohistochemistry; Biology; Lung; Neoplasm; Medicine; Kidney; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01404333019436243,"gpt":0.2458298286175261,"spread":0.2317864984231637,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0005643046,0.0002067423,0.0008404517,0.0002955426,0.00005398221,9.821384e-7,0.0004131444,0.00009915187,0.0001768809],"category_scores_gemma":[0.0002767179,0.0001283493,0.0001867922,0.0005205151,0.003472802,0.0000304943,0.00020122,0.0003135355,0.000006954282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001687419,"about_ca_system_score_gemma":0.0002799457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002185661,"about_ca_topic_score_gemma":0.00004271524,"domain_scores_codex":[0.9975163,0.0004784995,0.0007506546,0.0003244071,0.0005828783,0.0003472654],"domain_scores_gemma":[0.9977285,0.000510051,0.0003715252,0.00101278,0.0002765221,0.0001006675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000147107,0.0002436789,0.03125087,0.0003828485,0.00007046456,0.0001280994,0.001726375,0.00001498492,0.9627294,0.001666411,0.0006106927,0.001029088],"study_design_scores_gemma":[0.002136941,0.0008004953,0.4654513,0.0006023775,0.0001816449,0.00008956822,0.0004505063,0.00007088843,0.5283512,0.0003276361,0.001444205,0.000093198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919009,0.004429934,0.0001497632,0.00109163,0.0001626835,0.0004705282,0.00008327817,0.00001869243,0.001692635],"genre_scores_gemma":[0.9968243,0.0004993169,0.002058015,0.0001851194,0.0001404418,0.00001267602,0.00001109066,0.0000318533,0.0002371451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4343782,"threshold_uncertainty_score":0.9992391,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1486174444","doi":"10.1111/j.1750-3639.2010.00416.x","title":"Analysis of TSC Cortical Tubers by Deep Sequencing of TSC1, TSC2 and KRAS Demonstrates that Small Second‐Hit Mutations in these Genes are Rare Events","year":2010,"lang":"en","type":"article","venue":"Brain Pathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"TSC1; Tuberous sclerosis; TSC2; KRAS; Biology; Mutation; Exon; Point mutation; Coding region; Gene; Cancer research; Genetics; Pathology; Medicine; PI3K/AKT/mTOR pathway; Signal transduction","retraction":null,"screen_n_in":null,"score":{"opus":0.04662428903226076,"gpt":0.3055223138071808,"spread":0.2588980247749201,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005974105,0.0001596861,0.0006636173,0.0005828468,0.00004462587,0.000007327515,0.0001564698,0.0002171061,0.0003626334],"category_scores_gemma":[0.0008704014,0.0001460257,0.000119823,0.0006610957,0.0006106209,0.00005336977,0.00009462197,0.000435059,0.000003006248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003839638,"about_ca_system_score_gemma":0.000116963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001450938,"about_ca_topic_score_gemma":0.007858535,"domain_scores_codex":[0.9982699,0.0003088587,0.0004614096,0.0003755173,0.0002262667,0.0003580482],"domain_scores_gemma":[0.9982867,0.0008813061,0.0001697913,0.0003675103,0.0001455317,0.0001492007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003742019,0.00008928726,0.572744,0.00005007892,0.000147399,0.00007171663,0.0009411279,0.00003382572,0.4245365,0.00008282815,0.00001649239,0.001249384],"study_design_scores_gemma":[0.0009304925,0.0001536816,0.9743221,0.00004092688,0.0002895613,0.0001683776,0.002105868,0.003093646,0.01854054,0.0002218196,0.00001551103,0.0001174151],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997996,0.0003552508,0.000209203,0.0008296465,0.00003573752,0.0003029678,0.00009565733,0.0000189786,0.0001565908],"genre_scores_gemma":[0.9981902,0.00002280265,0.001359992,0.0001950895,0.00001343304,0.00002869698,0.00008451586,0.00002054657,0.00008469882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.405996,"threshold_uncertainty_score":0.5954754,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2809172769","doi":"10.1016/j.eururo.2018.06.007","title":"Somatic Bi-allelic Loss of TSC Genes in Eosinophilic Solid and Cystic Renal Cell Carcinoma","year":2018,"lang":"en","type":"article","venue":"European Urology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"National Cancer Institute; Howard Hughes Medical Institute","keywords":"Tuberous sclerosis; Renal cell carcinoma; TSC2; TSC1; Medicine; Clear cell; Somatic cell; Cancer research; Loss of heterozygosity; Kidney cancer; Pathology; Germline; PI3K/AKT/mTOR pathway; Biology; Gene; Allele; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03196774528037082,"gpt":0.2802978180835013,"spread":0.2483300728031305,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005123557,0.0001626621,0.0003789124,0.0003175747,0.00005350784,0.000009455672,0.0002083214,0.00005750081,0.0001947234],"category_scores_gemma":[0.0001680978,0.0001460448,0.00004392135,0.0002301052,0.0006379822,0.00003129302,0.0002614113,0.0002417423,0.0003462402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002486514,"about_ca_system_score_gemma":0.00006253643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005556587,"about_ca_topic_score_gemma":0.00004809521,"domain_scores_codex":[0.9979951,0.0005601756,0.0004156386,0.0003718616,0.0002039806,0.0004532172],"domain_scores_gemma":[0.9989949,0.0001784762,0.00009116002,0.0004746933,0.0001063854,0.0001543446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006530533,0.0004989809,0.2785417,0.0003867463,0.00004539375,0.001084763,0.002053858,0.00002440194,0.7106129,0.0002535282,0.0007453968,0.005099326],"study_design_scores_gemma":[0.002339279,0.002655398,0.9830215,0.00003071559,0.00004420206,0.0004240232,0.00003262621,0.001264143,0.008828704,0.0001422539,0.001079786,0.0001373514],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900055,0.0009028633,0.00007498163,0.0007239297,0.00007466313,0.0002628317,0.000003979008,0.00003218744,0.007919044],"genre_scores_gemma":[0.998551,0.00004053265,0.0003603122,0.0004129241,0.0002727594,0.000004272308,0.000006460064,0.00004974897,0.0003019666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7044799,"threshold_uncertainty_score":0.5955532,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2169878097","doi":"10.1093/cercor/bhs310","title":"Fetal Brain mTOR Signaling Activation in Tuberous Sclerosis Complex","year":2012,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; University of Pennsylvania; Perelman School of Medicine, University of Pennsylvania; Hersenstichting; Children's Hospital of Philadelphia; Congressionally Directed Medical Research Programs; Pfizer; U.S. Department of Defense","keywords":"mTORC2; mTORC1; TSC2; PI3K/AKT/mTOR pathway; Tuberous sclerosis; Biology; Cell biology; Protein kinase B; Cancer research; Neurogenesis; Signal transduction; Pathology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.1079589380246521,"gpt":0.3214117807447763,"spread":0.2134528427201242,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005408053,0.0002544906,0.0004383806,0.0003156308,0.0001353113,0.0000530915,0.0002402894,0.0001503473,0.001836574],"category_scores_gemma":[0.0004139165,0.0002445602,0.0001340559,0.000626996,0.0001289096,0.0004218906,0.0002085116,0.0005046392,0.0004186168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004036622,"about_ca_system_score_gemma":0.00009492031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004442243,"about_ca_topic_score_gemma":0.00006366781,"domain_scores_codex":[0.9974243,0.0001578587,0.0004444073,0.0003848252,0.00064521,0.0009434227],"domain_scores_gemma":[0.9986454,0.0002369727,0.000090459,0.0005097512,0.0001144069,0.0004030658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002139129,0.0004481887,0.2552527,0.00007491347,0.00004430528,0.000004357736,0.0004820294,0.000005143565,0.7167491,0.0003676316,0.006758261,0.01959938],"study_design_scores_gemma":[0.002190232,0.0002201174,0.9787694,0.0001942029,0.00002175546,0.00004387336,0.0002395714,0.001044163,0.01585587,0.00007792108,0.001079233,0.0002636468],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932812,0.00009551906,0.0004444673,0.002845768,0.000154089,0.000659823,0.00000744563,0.0001435944,0.002368047],"genre_scores_gemma":[0.9955559,0.000003081838,0.001764393,0.001408274,0.0005306535,0.00004717187,0.0001095261,0.00006502721,0.0005160091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7235167,"threshold_uncertainty_score":0.9990759,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049318603","doi":"10.1212/01.wnl.0000345365.92821.86","title":"Cyst-like tubers are associated with TSC2 and epilepsy in tuberous sclerosis complex","year":2009,"lang":"en","type":"article","venue":"Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Tuberous sclerosis; TSC1; Epilepsy; TSC2; Cyst; Medicine; Pathology; Mutation; Biology; Gene; Genetics; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.05709249351830022,"gpt":0.276812636362832,"spread":0.2197201428445318,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002833509,0.0002667292,0.0006520582,0.0003298109,0.0001142475,0.00003001474,0.0001740931,0.000228292,0.0001303066],"category_scores_gemma":[0.0002169111,0.0002348077,0.00005412352,0.0005598125,0.0003155339,0.00007618932,0.00007856384,0.0007758479,0.00003419581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000715011,"about_ca_system_score_gemma":0.0000649682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002949668,"about_ca_topic_score_gemma":0.001373764,"domain_scores_codex":[0.9975369,0.0002956316,0.0003408066,0.0006369021,0.0004107915,0.0007789789],"domain_scores_gemma":[0.9987746,0.0002967741,0.0001008568,0.0004413781,0.0001228998,0.0002634916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002652157,0.0008380426,0.9546143,0.00002882966,0.00008485789,0.001275545,0.000323441,0.0000814157,0.02924303,0.0002041271,0.003727001,0.006927195],"study_design_scores_gemma":[0.004268225,0.00460882,0.9884339,0.00007175978,0.00003682023,0.0006520268,0.00001849631,0.0009036448,0.00006032978,0.0001038596,0.0006600006,0.0001821042],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834682,0.0001299568,0.000009482478,0.01444373,0.0000596468,0.0005445493,0.00001546721,0.0001455189,0.001183413],"genre_scores_gemma":[0.9872897,0.00004621621,0.0001420268,0.01228091,0.00005366443,0.00002344587,0.00003787763,0.00004178324,0.00008443803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03381955,"threshold_uncertainty_score":0.9575181,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4291398401","doi":"10.1016/s1474-4422(22)00213-7","title":"Advances in the genetics and neuropathology of tuberous sclerosis complex: edging closer to targeted therapy","year":2022,"lang":"en","type":"review","venue":"The Lancet Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Seventh Framework Programme; ZonMw; BC Children's Hospital","keywords":"Tuberous sclerosis; TSC1; TSC2; Neuropathology; Epileptogenesis; Epilepsy; Autism; Vigabatrin; Medicine; Neuroscience; Everolimus; Megalencephaly; Disease; PI3K/AKT/mTOR pathway; Bioinformatics; Psychology; Biology; Pathology; Psychiatry; Genetics; Oncology; Anticonvulsant","retraction":null,"screen_n_in":null,"score":{"opus":0.2899669084982169,"gpt":0.4063470158097781,"spread":0.1163801073115611,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001309313,0.0004087396,0.00230817,0.0003229401,0.0001813166,0.00002122041,0.001224883,0.0001594046,0.0001759271],"category_scores_gemma":[0.0002482762,0.0002331277,0.000196956,0.0008906834,0.0004931805,0.00003259605,0.0005900682,0.001695731,0.00001525396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002555688,"about_ca_system_score_gemma":0.0001107082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000330385,"about_ca_topic_score_gemma":0.00004856806,"domain_scores_codex":[0.9941478,0.003326132,0.0006900065,0.0006519286,0.0004386368,0.0007454394],"domain_scores_gemma":[0.9962602,0.002025984,0.0002593949,0.001326251,0.00004659879,0.00008152475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003488107,0.0001301349,0.0009442421,0.001300677,0.00003946109,0.0001283596,0.0004567584,0.00002313605,0.0001922044,0.0002145026,0.0009158116,0.9953059],"study_design_scores_gemma":[0.0008228814,0.001672833,0.01682035,0.000227248,0.0001171441,0.001343155,0.00002050286,0.00003112303,0.000002555568,0.0001223049,0.9786478,0.0001721065],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0252743,0.9667511,0.000007144451,0.005131738,0.0002217886,0.002082234,0.00005515379,0.00003894643,0.0004375998],"genre_scores_gemma":[0.007746063,0.9828001,0.0001017231,0.008469502,0.0003567546,0.0003900692,0.00003835669,0.00008670262,0.00001077515],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9951338,"threshold_uncertainty_score":0.9506673,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2091535244","doi":"10.1002/pd.2590","title":"Fetal cardiac tumors: a single‐center experience of 40 cases","year":2010,"lang":"en","type":"article","venue":"Prenatal Diagnosis","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation; Mount Sinai Hospital","funders":"","keywords":"Tuberous sclerosis; Medicine; Rhabdomyoma; Fetus; Hydrops fetalis; Teratoma; Retrospective cohort study; Fetal echocardiography; Etiology; Pericardial effusion; Pregnancy; Obstetrics; Internal medicine; Cardiology; Surgery; Prenatal diagnosis; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.05100746445577049,"gpt":0.3173812719340918,"spread":0.2663738074783213,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000129489,0.0001801085,0.0003961833,0.0001430737,0.0000645998,0.00003442081,0.0002423613,0.00008428656,0.0008791503],"category_scores_gemma":[0.0009787499,0.0001577255,0.0002060904,0.0002554549,0.0003588856,0.0001799295,0.0002579194,0.0003470441,0.00008824904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004326291,"about_ca_system_score_gemma":0.00005717823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000635615,"about_ca_topic_score_gemma":0.0001005878,"domain_scores_codex":[0.9982696,0.00004820194,0.0003126722,0.000374063,0.0005759495,0.0004195785],"domain_scores_gemma":[0.9984937,0.0004020325,0.00007338272,0.0005960915,0.0001727406,0.0002620801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002561726,0.001384808,0.840464,0.0002334855,0.00008254231,0.0001745093,0.001420663,7.318058e-7,0.1364393,0.0001260987,0.001947141,0.01747056],"study_design_scores_gemma":[0.0009826192,0.0005542441,0.3409227,0.0004106486,0.00004414463,0.0002615683,0.0003108506,0.0000570443,0.6533712,0.00002044914,0.002836347,0.0002281787],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965689,0.0002618675,0.000006343556,0.0003595767,0.0002793912,0.000461759,0.0001500431,0.00007445847,0.001837665],"genre_scores_gemma":[0.9982264,0.00004425562,0.0009121575,0.00009446815,0.0001882286,0.0003400911,0.00003852497,0.00003387281,0.0001220269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5169318,"threshold_uncertainty_score":0.9626079,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2090531536","doi":"10.1002/ana.21037","title":"Unusually mild tuberous sclerosis phenotype is associated with<i>TSC2</i>R905Q mutation","year":2006,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Montreal Children's Hospital; Université de Montréal; McGill University; Montreal Neurological Institute and Hospital","funders":"U.S. Public Health Service","keywords":"Missense mutation; Tuberous sclerosis; TSC2; Phenotype; Mutation; Genetics; TSC1; Genotype-phenotype distinction; Genotype; Biology; Gene; Medicine; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.1190287504022719,"gpt":0.326980621472486,"spread":0.2079518710702141,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003467574,0.0002339827,0.0005527791,0.0002815331,0.0001058711,0.00001829512,0.000206385,0.0002113487,0.0002255818],"category_scores_gemma":[0.0002460756,0.0002108537,0.0001296936,0.0006233219,0.0003211092,0.00009800812,0.00007615324,0.0004002519,0.0000788765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001548115,"about_ca_system_score_gemma":0.0001249117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008194176,"about_ca_topic_score_gemma":0.0003333172,"domain_scores_codex":[0.9975397,0.0002346986,0.0004848701,0.0004842468,0.0006160128,0.000640469],"domain_scores_gemma":[0.9981033,0.0003636251,0.0002204383,0.0004631804,0.0007112095,0.0001382163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01238483,0.007137138,0.3114502,0.0003872077,0.001600588,0.001421134,0.001298184,0.001443472,0.3697657,0.004339719,0.2615547,0.02721711],"study_design_scores_gemma":[0.00244386,0.004476767,0.9630748,0.0000836715,0.00008909815,0.0001243199,0.00000997425,0.0005098487,0.02640744,0.0009350181,0.001629321,0.0002158699],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759345,0.0003090764,0.00004479516,0.02019426,0.00006967231,0.0003951919,0.00003582346,0.0001108644,0.00290583],"genre_scores_gemma":[0.9875282,0.000050739,0.0001174299,0.0116024,0.0001157787,0.00002419649,0.00008060698,0.00006094266,0.0004196774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6516246,"threshold_uncertainty_score":0.8598363,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2108199307","doi":"10.1007/s00415-010-5535-2","title":"MRI findings reveal three different types of tubers in patients with tuberous sclerosis complex","year":2010,"lang":"en","type":"article","venue":"Journal of Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Fluid-attenuated inversion recovery; Tuberous sclerosis; Magnetic resonance imaging; Dominance (genetics); Epilepsy; White matter; Medicine; Multiple sclerosis; Pathology; Radiology; Biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0329947950319435,"gpt":0.263154064209513,"spread":0.2301592691775695,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002829162,0.0001731676,0.0006833914,0.00045995,0.00004013141,0.00001088249,0.000285087,0.0001381487,0.0002189018],"category_scores_gemma":[0.0001814486,0.000119807,0.0001115711,0.0002572211,0.0002753943,0.00008213495,0.00009540245,0.001233532,0.000006980178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003227415,"about_ca_system_score_gemma":0.00008142119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005363575,"about_ca_topic_score_gemma":0.0003551887,"domain_scores_codex":[0.9980553,0.0001020704,0.000637866,0.0002026987,0.0006234517,0.0003786143],"domain_scores_gemma":[0.9986169,0.0002307485,0.0002753618,0.0003031563,0.0003812239,0.0001926028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00278865,0.0006348883,0.9356999,0.00003458831,0.00006770804,0.0000486942,0.00008710648,0.00002880917,0.05841529,0.00004185584,0.0008523795,0.00130012],"study_design_scores_gemma":[0.004993506,0.005787255,0.9875023,0.00006476748,0.00005377823,0.000247881,0.000004484094,0.00008820329,0.0009690906,0.00008185571,0.0001231059,0.00008376759],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960905,0.00001930363,0.00002004152,0.00324096,0.000234072,0.0002633211,0.000006181367,0.000007830451,0.000117847],"genre_scores_gemma":[0.998776,0.000009689405,0.0005774114,0.0004896246,0.00009743494,0.000002448601,0.000003442756,0.00003083811,0.00001314534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0574462,"threshold_uncertainty_score":0.5359151,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2095070946","doi":"10.1165/rcmb.2006-0372tr","title":"Molecular Pathogenesis of Lymphangioleiomyomatosis","year":2006,"lang":"en","type":"review","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Lymphangioleiomyomatosis; Pathogenesis; TSC2; Cancer research; Biology; Medicine; Genetics; Computational biology; Tuberous sclerosis; Pathology; Signal transduction","retraction":null,"screen_n_in":null,"score":{"opus":0.033638374071377,"gpt":0.3424831525332751,"spread":0.3088447784618981,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000569021,0.0004626328,0.003272293,0.0009243581,0.000036739,0.00001206883,0.000362618,0.0002681563,0.00001573508],"category_scores_gemma":[0.00008393013,0.0003470829,0.001125761,0.0006738994,0.0008919262,0.00002103149,0.0001629438,0.0003635539,0.000004986824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009210074,"about_ca_system_score_gemma":0.0008191926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003333992,"about_ca_topic_score_gemma":6.219257e-7,"domain_scores_codex":[0.9965492,0.0009129652,0.001329289,0.0004039911,0.0003554201,0.0004491083],"domain_scores_gemma":[0.9968935,0.0001705652,0.001717916,0.0005092621,0.0003796853,0.0003290865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000566005,0.0001769038,0.0003480485,0.003202047,0.0005012475,0.0005895925,0.00001010724,9.707843e-7,0.08105107,0.00007442162,0.0001217481,0.9138672],"study_design_scores_gemma":[0.001025683,0.005116036,0.0001045614,0.003441106,0.00231078,0.001178686,0.0000343529,0.000001030885,0.006768131,0.00002885754,0.9795439,0.0004469029],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03910949,0.9591852,0.0009233227,0.00002432808,0.00006299153,0.0003376767,0.00003442541,0.000009201206,0.0003133727],"genre_scores_gemma":[0.008591146,0.9887577,0.001971693,0.0004167512,0.0001110499,0.00001753414,0.00002008229,0.0001012215,0.0000128767],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9794222,"threshold_uncertainty_score":0.9998981,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2088586667","doi":"10.1371/journal.pone.0053565","title":"Predictors of Seizure Outcomes in Children with Tuberous Sclerosis Complex and Intractable Epilepsy Undergoing Resective Epilepsy Surgery: An Individual Participant Data Meta-Analysis","year":2013,"lang":"en","type":"review","venue":"PLoS ONE","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; McMaster University; University of Toronto","funders":"Stryker; Amgen","keywords":"Epilepsy surgery; Tuberous sclerosis; Epilepsy; Ictal; Medicine; Corpus callosotomy; Data extraction; Concordance; Seizure types; MEDLINE; Psychiatry; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.6469797994069294,"gpt":0.3855189138003011,"spread":0.2614608856066283,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002869527,0.001073817,0.01340952,0.002137142,0.000166281,0.0002032102,0.00122909,0.000501512,0.001013865],"category_scores_gemma":[0.001352875,0.0007353903,0.0009721399,0.002889521,0.0005746411,0.0006794003,0.001218468,0.001519121,0.00002372711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001618912,"about_ca_system_score_gemma":0.0009308945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003032449,"about_ca_topic_score_gemma":0.002551753,"domain_scores_codex":[0.9902849,0.001807567,0.002221783,0.001961344,0.002468265,0.001256131],"domain_scores_gemma":[0.9909554,0.003250391,0.001071819,0.003608882,0.0004150994,0.0006984042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00006034895,0.003911558,0.4449088,0.004840476,0.5365297,0.00001478136,0.0002190479,0.000006437627,0.0000108111,0.000007999043,0.0002270667,0.009263029],"study_design_scores_gemma":[0.0007676204,0.0006063563,0.3619247,0.003263117,0.6323761,0.0000422978,0.0001004974,0.0001349286,0.00001405525,0.000005629152,0.0001304051,0.0006343428],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2230503,0.7684422,0.000008565784,0.0001585486,0.00001384689,0.004729021,0.003459782,0.0001047721,0.00003296764],"genre_scores_gemma":[0.1733463,0.8143257,0.003366401,0.00007260554,0.0001329316,0.0009855182,0.007416484,0.000262164,0.00009181788],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.09584641,"threshold_uncertainty_score":0.9998993,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2945737519","doi":"10.1111/joa.12956","title":"New insights into a spectrum of developmental malformations related to<scp>mTOR</scp>dysregulations: challenges and perspectives","year":2019,"lang":"en","type":"review","venue":"Journal of Anatomy","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Stichting TSC Fonds; Seventh Framework Programme; Stichting Kinderen Kankervrij; Austrian Science Fund; European Commission","keywords":"Megalencephaly; Cortical dysplasia; PI3K/AKT/mTOR pathway; Epileptogenesis; Tuberous sclerosis; Neuroscience; Autism; Sirolimus; Epilepsy; Autism spectrum disorder; Zebrafish; Disease; Medicine; Bioinformatics; Biology; Pathology; Genetics; Signal transduction; Psychiatry; Internal medicine; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.09692802050373925,"gpt":0.3611498636403577,"spread":0.2642218431366185,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004007065,0.0003207021,0.001775449,0.001587424,0.00007784074,0.00003515254,0.0002843523,0.0002500502,0.00009261673],"category_scores_gemma":[0.0004106039,0.000240927,0.0003729752,0.0006299925,0.00008752245,0.000300039,0.0001629884,0.0007728616,0.00006468125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005736904,"about_ca_system_score_gemma":0.001717934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001489242,"about_ca_topic_score_gemma":0.00002080367,"domain_scores_codex":[0.9973284,0.0001443875,0.001242912,0.0002544586,0.000757388,0.0002724265],"domain_scores_gemma":[0.9977025,0.0003950991,0.0008330784,0.0002669957,0.0004024422,0.0003999326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000317373,0.0003232109,0.00009444791,0.01329203,0.002383634,0.00007860354,0.03035628,0.000003544332,0.00003854263,0.01133899,0.006485779,0.9355732],"study_design_scores_gemma":[0.001272611,0.0007704036,0.006206921,0.0213645,0.0007800716,0.001845009,0.005588609,0.00001082019,0.00002024637,0.0009602829,0.9610192,0.0001613397],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00418216,0.9907445,0.00003766147,0.0008478481,0.000116042,0.0007971409,0.00000338248,0.00001425006,0.00325697],"genre_scores_gemma":[0.00237762,0.9899464,0.006320698,0.00001444312,0.0001418256,0.000006214695,0.000008664778,0.0000488695,0.001135244],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9545334,"threshold_uncertainty_score":0.9824719,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2471465220","doi":"10.1227/neu.0000000000000875","title":"Resective Epilepsy Surgery for Tuberous Sclerosis in Children","year":2015,"lang":"en","type":"article","venue":"Neurosurgery","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Hospital for Sick Children; McMaster University; British Columbia Children's Hospital","funders":"Hospital for Sick Children","keywords":"Medicine; Tuberous sclerosis; Epilepsy surgery; Hazard ratio; Epilepsy; Confidence interval; Retrospective cohort study; Pediatrics; Surgery; Proportional hazards model; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.1565963118436571,"gpt":0.3212493141022424,"spread":0.1646530022585853,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001666211,0.00028114,0.000782162,0.000770336,0.00008576908,0.0000640574,0.0001737406,0.0001647252,0.00004519126],"category_scores_gemma":[0.003810046,0.0002748094,0.000323839,0.0009583154,0.0001651657,0.0001953311,0.0001290197,0.0004641232,0.0001053083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000260788,"about_ca_system_score_gemma":0.0005112958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003930192,"about_ca_topic_score_gemma":0.00004050485,"domain_scores_codex":[0.9967093,0.0002581181,0.0006318829,0.0007144621,0.0007561735,0.0009300971],"domain_scores_gemma":[0.9966466,0.001675404,0.0001076327,0.0006872261,0.0003471065,0.0005360593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000813549,0.0003789494,0.9273207,0.00003366395,0.00003573812,0.00004032741,0.00008156137,0.00003633223,0.002718711,0.00003679504,0.06289169,0.005611941],"study_design_scores_gemma":[0.00169091,0.0002600244,0.9932855,0.0001575159,0.00002394326,0.0002627828,0.00003323246,0.0002948934,0.002707315,0.0002002023,0.0008347519,0.0002489423],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954713,0.0003116352,0.00007886065,0.001539343,0.0005184709,0.001262098,0.0000463212,0.0001685519,0.0006034183],"genre_scores_gemma":[0.9972618,0.00005997057,0.0002799091,0.001089646,0.0004297552,0.0003411038,0.00006071404,0.0001075466,0.0003695044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06596474,"threshold_uncertainty_score":0.9999704,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2119588829","doi":"10.1136/thx.2004.035154","title":"Emerging clinical picture of lymphangioleiomyomatosis","year":2005,"lang":"en","type":"article","venue":"Thorax","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Coalition for Research in Women's Health","funders":"","keywords":"Medicine; Lymphangioleiomyomatosis; Pneumothorax; Tuberous sclerosis; Pulmonary function testing; Cross-sectional study; Chest pain; Pediatrics; Surgery; Internal medicine; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.07715793496707438,"gpt":0.4263095627401403,"spread":0.349151627773066,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005341134,0.0001018486,0.000350199,0.0001187835,0.00003828561,0.000007017457,0.0001473612,0.00009723534,0.0007475229],"category_scores_gemma":[0.000158448,0.00008354703,0.0001793359,0.0002644163,0.0001182733,0.00004894368,0.000093569,0.0001508749,0.0002437051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004405534,"about_ca_system_score_gemma":0.0000786419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001359844,"about_ca_topic_score_gemma":0.000006137006,"domain_scores_codex":[0.9986424,0.00008588587,0.0004121006,0.0002103096,0.0003717979,0.0002774732],"domain_scores_gemma":[0.9990867,0.0001154207,0.00007025337,0.0004369683,0.0001184884,0.0001721086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0004879257,0.0009581937,0.4054015,0.0002127744,0.0002884305,0.00002743554,0.0007443671,0.0000352974,0.08146795,0.001587597,0.02442055,0.4843679],"study_design_scores_gemma":[0.003559997,0.0006208243,0.8687013,0.0003698322,0.0001775929,0.0001096952,0.0002822702,0.002513772,0.03981192,0.0001713095,0.08338592,0.000295602],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866585,0.0004426716,0.0003181042,0.003064443,0.00007588747,0.0002052594,0.000004262725,0.00008041522,0.009150498],"genre_scores_gemma":[0.990905,0.0000674789,0.006970979,0.0005896209,0.0004902144,0.000007346958,0.000006982562,0.00002377724,0.0009385967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4840724,"threshold_uncertainty_score":0.8184852,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2060806258","doi":"10.1111/dmcn.12573","title":"Does vigabatrin treatment for infantile spasms cause visual field defects? An international multicentre study","year":2014,"lang":"en","type":"article","venue":"Developmental Medicine & Child Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Vigabatrin; Medicine; Tuberous sclerosis; Pediatrics; Cohort; Epilepsy; Anesthesia; Anticonvulsant; Internal medicine; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.03499858674845663,"gpt":0.354051621417028,"spread":0.3190530346685714,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003159347,0.0003439578,0.0005782976,0.0003351618,0.0002253447,0.00002015053,0.0002803766,0.0001248725,0.0006717767],"category_scores_gemma":[0.0006789145,0.0002102268,0.00008314032,0.0001667675,0.0001441553,0.0001147142,0.0001564914,0.0003234992,0.00004817568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001191544,"about_ca_system_score_gemma":0.00008020003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002575982,"about_ca_topic_score_gemma":0.001021845,"domain_scores_codex":[0.9974727,0.0001952028,0.0005117143,0.0007634525,0.0004925914,0.0005643273],"domain_scores_gemma":[0.9984344,0.0006521548,0.0001080239,0.0003366153,0.0001206826,0.0003481674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003432663,0.003059736,0.9394768,0.00003962796,0.0003470025,0.0001762089,0.002822805,0.000005617278,0.00464713,0.000101332,0.0009064459,0.04498459],"study_design_scores_gemma":[0.0200063,0.02707106,0.9092399,0.0000699333,0.0001964682,0.0004059944,0.000520091,0.001180136,0.006239923,0.00002967101,0.03472234,0.0003181479],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815261,0.00001123911,0.0001034454,0.01374026,0.001158406,0.002118155,0.000009919487,0.0001305811,0.001201921],"genre_scores_gemma":[0.9902866,0.00003651265,0.000414667,0.007531035,0.000970385,0.0002454014,0.0001712309,0.00005430038,0.0002899052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04466644,"threshold_uncertainty_score":0.8572802,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2068140255","doi":"10.1016/j.crad.2014.10.001","title":"Ten uncommon and unusual variants of renal angiomyolipoma (AML): radiologic–pathologic correlation","year":2014,"lang":"en","type":"review","venue":"Clinical Radiology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; Angiomyolipoma; Pathology; Correlation; Radiology; Kidney; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.2088807863623147,"gpt":0.4691037694563713,"spread":0.2602229830940566,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004042557,0.0005594844,0.006048721,0.0004126623,0.00008603569,0.00001251293,0.0005021322,0.002126735,0.0001456148],"category_scores_gemma":[0.006385855,0.0003839862,0.0009551984,0.000434877,0.001760746,0.0000387585,0.0004026059,0.001917086,0.0001378665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001140606,"about_ca_system_score_gemma":0.0004204669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000140797,"about_ca_topic_score_gemma":0.000004691618,"domain_scores_codex":[0.9917328,0.003533339,0.002624794,0.001136804,0.0002932362,0.0006789844],"domain_scores_gemma":[0.989823,0.007428671,0.001091856,0.001058817,0.0001777601,0.0004198635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002454756,0.0002809136,0.009729808,0.002930946,0.0005082902,0.0002779924,0.00001490149,0.000002367981,0.000009809322,0.001404771,0.005085461,0.9795092],"study_design_scores_gemma":[0.00431301,0.0108431,0.1148638,0.008074878,0.003270808,0.01193425,0.00001069913,0.0007422851,5.783382e-7,0.0009825933,0.8440947,0.0008693187],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004450552,0.9908304,0.0009628662,0.0001837786,0.0007352178,0.001393159,0.00004969854,0.00009709783,0.001297212],"genre_scores_gemma":[0.004490723,0.9916763,0.001476539,0.0002140005,0.001098001,0.00007287237,0.0004453076,0.00006920962,0.0004570107],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.97864,"threshold_uncertainty_score":0.9998612,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2040125659","doi":"10.1016/j.rmed.2008.11.007","title":"Pregnancy experiences among women with lymphangioleiomyomatosis","year":2008,"lang":"en","type":"article","venue":"Respiratory Medicine","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Women's Health Research Institute; Women's College Hospital; University of Toronto","funders":"","keywords":"Medicine; Pregnancy; Lymphangioleiomyomatosis; Miscarriage; Obstetrics; Quality of life (healthcare); DLCO; Premature birth; Pneumothorax; Pediatrics; Gestation; Lung; Internal medicine; Surgery; Lung function; Diffusing capacity","retraction":null,"screen_n_in":null,"score":{"opus":0.07895492884119386,"gpt":0.3038386841582927,"spread":0.2248837553170989,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003189203,0.0002914432,0.0006307643,0.0003645445,0.0002777773,0.000008630097,0.0002582015,0.0001056914,0.001738579],"category_scores_gemma":[0.0002120889,0.0001884447,0.00004928641,0.0008550195,0.001656585,0.0001734747,0.00007369388,0.0002036557,0.00009333903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002646577,"about_ca_system_score_gemma":0.0003117135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006313395,"about_ca_topic_score_gemma":0.000009313018,"domain_scores_codex":[0.9969314,0.0001141355,0.0004232157,0.0005313768,0.00122593,0.0007739201],"domain_scores_gemma":[0.9980989,0.0001177067,0.000115711,0.0007466148,0.0002299828,0.0006911329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001021594,0.0004936124,0.8857989,0.0003465237,0.0002927587,0.002413153,0.05407199,0.000004289957,0.02955134,0.0001154956,0.01371524,0.01217508],"study_design_scores_gemma":[0.008072869,0.006649094,0.9453732,0.002753752,0.00006025093,0.0006946122,0.01323648,0.00004295594,0.007497953,0.00001327333,0.01513254,0.0004729879],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871214,0.002611107,0.00009063218,0.0004059422,0.00008791447,0.00060053,0.000001158183,0.0002309776,0.008850338],"genre_scores_gemma":[0.9963658,0.0001047321,0.0001699125,0.001193336,0.0003943252,0.0006642818,0.000003342418,0.00005775402,0.001046457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05957431,"threshold_uncertainty_score":0.9991739,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016834366","doi":"10.1111/epi.12761","title":"Interictal high frequency oscillations correlating with seizure outcome in patients with widespread epileptic networks in tuberous sclerosis complex","year":2014,"lang":"en","type":"article","venue":"Epilepsia","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"Waksman Foundation of Japan; Ontario Brain Institute","keywords":"Ictal; Tuberous sclerosis; Epilepsy surgery; Epilepsy; Thresholding; Correlation; Electroencephalography; Cardiology; Medicine; Psychology; Neuroscience; Radiology; Mathematics; Artificial intelligence","retraction":null,"screen_n_in":null,"score":{"opus":0.02938646904827776,"gpt":0.2529273313569578,"spread":0.22354086230868,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004976176,0.0004342893,0.0008550084,0.0004974401,0.0001610673,0.00007788614,0.0002893718,0.0001900846,0.0003424633],"category_scores_gemma":[0.0003463817,0.0003438144,0.00007549016,0.001323537,0.0002816476,0.0002748311,0.0001473769,0.001037461,0.00008014574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005002287,"about_ca_system_score_gemma":0.00008468867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001518294,"about_ca_topic_score_gemma":0.001737478,"domain_scores_codex":[0.9963725,0.0003007808,0.0008650229,0.0007220895,0.0007921375,0.0009474676],"domain_scores_gemma":[0.99797,0.0005279465,0.0002163841,0.0007537515,0.000239689,0.0002922269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004171344,0.0003799691,0.9889503,0.0000455593,0.00004152176,0.00002207078,0.00030979,0.005072557,0.00017173,0.0003965253,0.0001840645,0.004008768],"study_design_scores_gemma":[0.006517531,0.001443915,0.9677222,0.0009730033,0.00004283011,0.00002462734,0.00007443633,0.02274889,0.00000540595,0.00004825068,0.00002430655,0.0003745849],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927081,0.00002891752,0.003890363,0.0005206968,0.0001428921,0.001249002,0.00001545453,0.0001330163,0.001311492],"genre_scores_gemma":[0.990992,0.000004076759,0.007974684,0.0004220713,0.0001086718,0.0001083154,0.0002061619,0.0001077056,0.00007630105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02122809,"threshold_uncertainty_score":0.9999014,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2156792909","doi":"10.1111/j.1528-1167.2005.14005.x","title":"Characterizing Magnetoencephalographic Spike Sources in Children with Tuberous Sclerosis Complex","year":2005,"lang":"en","type":"article","venue":"Epilepsia","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Ictal; Tuberous sclerosis; Magnetoencephalography; Electroencephalography; Epilepsy; Magnetic resonance imaging; Medicine; Audiology; Neuroscience; Psychology; Radiology","retraction":null,"screen_n_in":null,"score":{"opus":0.04192423217620788,"gpt":0.2691074735574591,"spread":0.2271832413812512,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003485532,0.0003384554,0.0005688522,0.000572657,0.000159671,0.00009176234,0.0003339248,0.0001222136,0.001087905],"category_scores_gemma":[0.00004105095,0.0002854924,0.0001198371,0.0009795433,0.0003462905,0.0002539472,0.0001280794,0.0005928851,0.0003174044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001383513,"about_ca_system_score_gemma":0.0000802547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004940083,"about_ca_topic_score_gemma":0.0003153466,"domain_scores_codex":[0.9971725,0.0001142118,0.0004652598,0.0006424449,0.0006997387,0.0009058077],"domain_scores_gemma":[0.9987741,0.00006862655,0.0001023741,0.000644932,0.00009243959,0.0003175575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001658016,0.000342767,0.9397177,0.00002121873,0.00006768772,0.00001553441,0.000347778,0.0000348878,0.03492453,0.0001079095,0.0005376082,0.02371659],"study_design_scores_gemma":[0.002573962,0.0005911639,0.9927275,0.0002343544,0.00004235821,0.0004094405,0.00006853502,0.000454506,0.0009749178,0.00001140314,0.001606205,0.0003056385],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936306,0.0004037826,0.00004376622,0.003318984,0.00002607823,0.0008837099,0.00001712238,0.0002027733,0.001473156],"genre_scores_gemma":[0.9929009,0.0001345002,0.004691326,0.001434677,0.0003705789,0.0000942341,0.00009846466,0.00007588065,0.0001994352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05300983,"threshold_uncertainty_score":0.9999597,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2062072434","doi":"10.1007/s00401-013-1135-4","title":"mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis","year":2013,"lang":"en","type":"article","venue":"Acta Neuropathologica","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"NIHR Great Ormond Street Hospital Biomedical Research Centre; National Institutes of Health; Great Ormond Street Hospital Charity; Vector Institute; Great Ormond Street Hospital for Children; National Institute for Health and Care Research","keywords":"Autophagy; Cortical dysplasia; Tuberous sclerosis; PI3K/AKT/mTOR pathway; Biology; Pathology; Cell biology; Population; Dysplasia; Epilepsy; Medicine; Neuroscience; Apoptosis; Signal transduction; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.09751427904435675,"gpt":0.2932840404801422,"spread":0.1957697614357855,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004755568,0.0002776055,0.0006007846,0.0002064232,0.0002169357,0.00009281043,0.0002959898,0.000167124,0.0008384954],"category_scores_gemma":[0.001018115,0.000231763,0.0000650416,0.0002318979,0.000499157,0.0004627283,0.0004586389,0.0007510847,0.0001212866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000907563,"about_ca_system_score_gemma":0.00009703576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00032747,"about_ca_topic_score_gemma":0.00004004543,"domain_scores_codex":[0.99687,0.0004439885,0.0009191975,0.0005275768,0.0006305175,0.0006087343],"domain_scores_gemma":[0.9981811,0.0007144936,0.0001451448,0.0004837366,0.0001720226,0.0003035013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000124369,0.0003585658,0.1494003,0.00007788374,0.00001828886,0.0001795554,0.001228595,8.732635e-7,0.8450427,0.0001267008,0.00006633536,0.003375861],"study_design_scores_gemma":[0.0008543045,0.0005942588,0.9783527,0.000299791,0.00003098779,0.0002923953,0.000169496,0.0003229548,0.01881792,0.0000452645,0.0000271079,0.0001928425],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998018,0.0001325043,0.00006006897,0.000684891,0.00006432051,0.0007146677,0.00002207303,0.00009833142,0.0002051606],"genre_scores_gemma":[0.9975787,0.0001365331,0.001570621,0.0003627499,0.00004615855,0.000156346,0.00003413186,0.00002960597,0.00008520258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8289524,"threshold_uncertainty_score":0.9451023,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2095191782","doi":"10.1016/s0920-1211(02)00216-4","title":"α-[11C]-Methyl-l-tryptophan PET identifies the epileptogenic tuber and correlates with interictal spike frequency","year":2003,"lang":"en","type":"article","venue":"Epilepsy Research","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council","keywords":"Ictal; Quinolinic acid; Epilepsy; Electroencephalography; Alpha (finance); Positron emission tomography; Kynurenine; Neuroscience; Nuclear medicine; Medicine; Psychology; Tryptophan; Surgery; Chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.06368178254454629,"gpt":0.3504152165015882,"spread":0.2867334339570419,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00393802,0.0003495019,0.0005188988,0.0004944337,0.0008064248,0.000337014,0.000547521,0.000131876,0.002656028],"category_scores_gemma":[0.001688824,0.000218506,0.0001376984,0.001432778,0.001933424,0.0002426817,0.0003750798,0.002064145,0.0007669402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00019712,"about_ca_system_score_gemma":0.000417719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003479684,"about_ca_topic_score_gemma":0.0002429802,"domain_scores_codex":[0.993935,0.001323906,0.0004920182,0.0008588719,0.001972412,0.001417738],"domain_scores_gemma":[0.9960252,0.001396864,0.00007268897,0.001223571,0.0007659402,0.0005157174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008164982,0.000575394,0.7990272,0.0003127384,0.0004857451,0.0008600841,0.002240082,0.000003983189,0.1594418,0.01288595,0.01952264,0.003827889],"study_design_scores_gemma":[0.006081196,0.004823965,0.9204959,0.000894176,0.0001616451,0.005132548,0.006946142,0.0003923755,0.03639263,0.008311179,0.009419411,0.0009488428],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752905,0.002646102,0.00008262776,0.00253596,0.0001915671,0.001346354,0.00001422339,0.00009582792,0.01779678],"genre_scores_gemma":[0.990739,0.0004207368,0.00104565,0.0001635334,0.0001840831,0.0002627626,0.00001859072,0.00009742921,0.007068239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1230492,"threshold_uncertainty_score":0.9982557,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2082671795","doi":"10.1111/j.1528-1167.2007.01486.x","title":"Evaluation of epileptogenic networks in children with tuberous sclerosis complex using EEG‐fMRI","year":2008,"lang":"en","type":"article","venue":"Epilepsia","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Ictal; Tuberous sclerosis; Epilepsy; Medicine; Neuroscience; Electroencephalography; Temporal lobe; Neuroimaging; Lesion; Magnetic resonance imaging; Audiology; Psychology; Pathology; Radiology","retraction":null,"screen_n_in":null,"score":{"opus":0.1797222646803345,"gpt":0.334493558754548,"spread":0.1547712940742135,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001603309,0.0002763812,0.0006437014,0.0003822969,0.0001558116,0.00001445662,0.0002332151,0.0001497642,0.0007063581],"category_scores_gemma":[0.0001645394,0.0002469289,0.0001287453,0.001079007,0.0003848024,0.0001425301,0.0001080136,0.0004261532,0.00003144705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000472161,"about_ca_system_score_gemma":0.0004610709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009719338,"about_ca_topic_score_gemma":0.0001331822,"domain_scores_codex":[0.9959525,0.0004813055,0.0006101466,0.0004496965,0.001865775,0.0006405401],"domain_scores_gemma":[0.9981542,0.0001011994,0.0001819701,0.0007107851,0.0006479886,0.000203921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002200737,0.0004117913,0.9572311,0.00001534378,0.0002171735,0.000007339072,0.0002896574,0.01937813,0.01445733,0.00003722148,0.000683007,0.007051853],"study_design_scores_gemma":[0.004472089,0.0004046305,0.8922923,0.0002232519,0.0002386586,0.0006649137,0.0000435674,0.1006979,0.0007285005,0.00002055947,0.000007548734,0.0002060629],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958516,0.0007054064,0.001101541,0.0001268077,0.00004317605,0.001499873,0.00001014794,0.00005953843,0.0006019421],"genre_scores_gemma":[0.9961537,0.0001050517,0.003265909,0.0001102563,0.000132178,0.00005857206,0.00008087415,0.00006964249,0.00002387967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08131979,"threshold_uncertainty_score":0.9999983,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4205203491","doi":"10.1038/s41379-021-00923-6","title":"Eosinophilic vacuolated tumor (EVT) of kidney demonstrates sporadic TSC/MTOR mutations: next-generation sequencing multi-institutional study of 19 cases","year":2021,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; McGill University; University of British Columbia; St. John’s Health Sciences Centre; University of Calgary","funders":"Ministerstvo Zdravotnictví Ceské Republiky","keywords":"Tuberous sclerosis; Eosinophilic; Pathology; CD117; Biology; Angiomyolipoma; Molecular pathology; Vimentin; Immunohistochemistry; Medicine; Kidney; Genetics; Stem cell","retraction":null,"screen_n_in":null,"score":{"opus":0.2331893904700749,"gpt":0.3486529196780956,"spread":0.1154635292080208,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003440098,0.0002054232,0.0005756055,0.000296753,0.0001672698,0.0000170784,0.000122951,0.0001116403,0.0001502008],"category_scores_gemma":[0.001772895,0.0001918897,0.00009715349,0.0004420486,0.0003114162,0.000136431,0.00008528342,0.0002648795,0.00001012834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002057837,"about_ca_system_score_gemma":0.00189542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003859187,"about_ca_topic_score_gemma":0.0003707424,"domain_scores_codex":[0.9977394,0.0003372324,0.0006888009,0.0005054327,0.0004176286,0.0003115446],"domain_scores_gemma":[0.9982788,0.0001606775,0.0002020907,0.0004648952,0.0006391342,0.0002543996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008785699,0.001366573,0.04957326,0.0001153322,0.00009689598,0.002499766,0.001840668,0.002047166,0.9414182,0.0001498266,0.00007084742,0.0007335986],"study_design_scores_gemma":[0.01431799,0.003655623,0.2514838,0.0004422599,0.0007004428,0.0153415,0.00546853,0.3373865,0.3698659,0.0006313544,0.00003535992,0.0006707397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942197,0.000728742,0.003650404,0.0003919716,0.0001278715,0.0006827692,0.00009485914,0.00005429055,0.00004938163],"genre_scores_gemma":[0.9930219,0.00001892273,0.006063781,0.0002759737,0.00007874052,0.0000639126,0.0003566016,0.00002613048,0.00009403382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5715523,"threshold_uncertainty_score":0.7825035,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1608451494","doi":"10.1111/j.1528-1167.2007.01112.x","title":"Surgical Outcome in Tuberous Sclerosis Complex: A Multicenter Survey","year":2007,"lang":"en","type":"article","venue":"Epilepsia","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Children's Hospital; University of British Columbia; McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Tuberous sclerosis; Ictal; Medicine; Epilepsy; Retrospective cohort study; Epilepsy surgery; Multicenter study; Pediatrics; Surgery; Radiology; Randomized controlled trial; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.1974302988272319,"gpt":0.3913609928076874,"spread":0.1939306939804555,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.003229815,0.0002951894,0.0007128511,0.0004481537,0.00009461175,0.00004907681,0.0002976234,0.0001883626,0.001462411],"category_scores_gemma":[0.0005674657,0.0002663548,0.0001807289,0.0008596159,0.0002228821,0.000105141,0.0002089803,0.0007201325,0.0009015584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003565638,"about_ca_system_score_gemma":0.00006238661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002555765,"about_ca_topic_score_gemma":0.002600719,"domain_scores_codex":[0.9961874,0.0003109728,0.0009264085,0.0005917184,0.0008409953,0.001142432],"domain_scores_gemma":[0.9975454,0.0009939029,0.00008308791,0.0006948031,0.0001949651,0.0004879056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009452531,0.000618681,0.9870433,0.00004055523,0.00003171552,0.0004362326,0.0001546414,0.000004910474,0.003221395,0.0001364818,0.002365302,0.005001509],"study_design_scores_gemma":[0.005309217,0.0002141034,0.9897393,0.0001021721,0.00001414557,0.0001347649,0.000054778,0.0006240757,0.0003735351,0.000009606957,0.003179517,0.0002447758],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932417,0.0001325276,0.0002305161,0.0008564345,0.0001871913,0.0007439025,0.00003080029,0.0001345838,0.004442361],"genre_scores_gemma":[0.9965822,0.00002249614,0.001677452,0.0006095775,0.0001767358,0.0000223606,0.0001141114,0.00006663599,0.0007284269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004756733,"threshold_uncertainty_score":0.9999788,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2268769076","doi":"10.1016/j.semcdb.2016.01.040","title":"The role of mTOR signalling in neurogenesis, insights from tuberous sclerosis complex","year":2016,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; Tuberous Sclerosis Association; Parc Geneteg Cymru; Wellcome Trust","keywords":"Neurogenesis; Tuberous sclerosis; TSC1; PI3K/AKT/mTOR pathway; Biology; Neuroscience; TSC2; Mechanistic target of rapamycin; Signal transduction; Cell biology; Psychology; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.06305530920500814,"gpt":0.3057241719922111,"spread":0.242668862787203,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002935016,0.0004196043,0.001565028,0.0003534437,0.0001042826,0.00001695509,0.0003869797,0.0003955661,0.00007946853],"category_scores_gemma":[0.00008376624,0.0002489575,0.0001480881,0.000388781,0.0004395564,0.00002777832,0.0004821406,0.000430469,0.00005361619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002772782,"about_ca_system_score_gemma":0.0004161074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002939886,"about_ca_topic_score_gemma":0.000226728,"domain_scores_codex":[0.9972097,0.0003938884,0.001013871,0.0006576051,0.0002046134,0.0005202883],"domain_scores_gemma":[0.9976054,0.001730899,0.0002231527,0.0002647023,0.0000435973,0.0001322447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000721692,0.0001226113,0.005015129,0.0007396784,0.00006522332,0.00002158463,0.0002194647,4.643522e-8,0.02263634,0.00004082458,0.00006958048,0.9709973],"study_design_scores_gemma":[0.001703646,0.0003955053,0.005671106,0.02504665,0.0001153184,0.0001207495,0.0005547818,0.00001505542,0.005779034,0.0006871798,0.9592138,0.000697204],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09727488,0.9010848,0.000001137609,0.0000222093,0.00008707283,0.0007161044,0.0000589329,0.00001363478,0.0007411993],"genre_scores_gemma":[0.03530398,0.9634675,0.0007273644,0.00003888143,0.00005320579,0.0001157461,0.0001643513,0.00004567305,0.00008322595],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9703001,"threshold_uncertainty_score":0.9999962,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1989822657","doi":"10.1016/j.braindev.2014.08.010","title":"Infantile tauopathies: Hemimegalencephaly; tuberous sclerosis complex; focal cortical dysplasia 2; ganglioglioma","year":2014,"lang":"en","type":"review","venue":"Brain and Development","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Cortical dysplasia; Biology; Tuberous sclerosis; Tauopathy; Tau protein; Neuroscience; Hemimegalencephaly; Pathology; Cell biology; Neurodegeneration; Epilepsy; Medicine; Alzheimer's disease; Disease","retraction":null,"screen_n_in":null,"score":{"opus":0.1129389095415735,"gpt":0.3528344192236026,"spread":0.2398955096820291,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001178688,0.0009540842,0.003317108,0.0007576829,0.0004384508,0.0001958186,0.0004481963,0.0006111984,0.0007121357],"category_scores_gemma":[0.0006424893,0.0007704301,0.0003697732,0.0007830129,0.0005609405,0.00008141672,0.0006659573,0.001117411,0.0008216827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003904802,"about_ca_system_score_gemma":0.001295049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002931148,"about_ca_topic_score_gemma":0.00002391246,"domain_scores_codex":[0.9944006,0.0004009374,0.001556578,0.001259359,0.001206732,0.001175845],"domain_scores_gemma":[0.9966598,0.001074912,0.0002907196,0.0008275258,0.0002105809,0.0009364859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005263119,0.0002356397,0.0001575848,0.01556189,0.0003185096,0.0001691844,0.0002847282,8.172218e-8,0.00004256635,0.0001918586,0.02962462,0.9533607],"study_design_scores_gemma":[0.001270387,0.0002940954,0.003954095,0.01631271,0.0002813389,0.001991644,0.00005027574,0.00003493961,0.00002850268,0.000009675093,0.9749609,0.0008113906],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001494992,0.9923228,0.0005192132,0.0003726878,0.0002380202,0.002287296,0.00004322398,0.0002982382,0.002423506],"genre_scores_gemma":[0.002144564,0.9840875,0.009745358,0.001129089,0.0003932893,0.0005619081,0.0004993545,0.000221299,0.001217687],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9525493,"threshold_uncertainty_score":0.9999563,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2783940554","doi":"10.1002/ana.25149","title":"Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy","year":2018,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Carleton University","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Citizens United for Research in Epilepsy","keywords":"mTORC1; mTORC2; PI3K/AKT/mTOR pathway; Protein kinase B; Mechanistic target of rapamycin; Neuroscience; Biology; Signal transduction; Epilepsy; Medicine; Cancer research; Cell biology","retraction":null,"screen_n_in":null,"score":{"opus":0.1752259130654098,"gpt":0.3967519659285001,"spread":0.2215260528630904,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003817232,0.0001121123,0.000490366,0.000284317,0.00003787511,0.000002876194,0.0001422408,0.00009389818,0.0005714933],"category_scores_gemma":[0.0001784279,0.0001060425,0.00004849404,0.0002091479,0.0006151593,0.0000293894,0.0001350225,0.0002016179,0.00001056245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002722127,"about_ca_system_score_gemma":0.00003681711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001953197,"about_ca_topic_score_gemma":0.0001209805,"domain_scores_codex":[0.9986053,0.0001881757,0.0004035918,0.0002711185,0.0002032741,0.0003286073],"domain_scores_gemma":[0.9991147,0.0001365569,0.0001167489,0.0003170182,0.000212592,0.0001024104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001284484,0.0004308003,0.3288022,0.0001567247,0.0000387546,0.00007883024,0.0001916505,0.000002731095,0.6611131,0.002561577,0.004705643,0.0006334082],"study_design_scores_gemma":[0.001235488,0.005705501,0.9560063,0.00002679583,0.000008873082,0.00006902995,0.00001250399,0.0005311625,0.03010914,0.004859226,0.001357692,0.00007821435],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940871,0.00007162955,0.00004804905,0.004138478,0.00003770535,0.0002474355,0.00001543884,0.00001439821,0.001339782],"genre_scores_gemma":[0.9973611,0.00002092064,0.0003651944,0.002101988,0.0000708802,0.000005894741,0.00001483044,0.00001784954,0.00004140074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.631004,"threshold_uncertainty_score":0.6257451,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2743228358","doi":"10.1007/s00330-017-4988-4","title":"Renal angiomyolipoma without visible fat: Can we make the diagnosis using CT and MRI?","year":2017,"lang":"en","type":"review","venue":"European Radiology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Neuroradiology; Medicine; Interventional radiology; Radiology; Angiomyolipoma; Ultrasound; Magnetic resonance imaging; Kidney; Neurology; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.2554168659932295,"gpt":0.4109629168735145,"spread":0.1555460508802851,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001208118,0.0005892384,0.002235697,0.000349044,0.0005395272,0.0001359319,0.0009167416,0.0001102321,0.0001219473],"category_scores_gemma":[0.0004076726,0.0003632259,0.0004463831,0.0002070623,0.0009276107,0.00003449997,0.0007037077,0.001141109,0.0001922898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001750643,"about_ca_system_score_gemma":0.000332101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001494186,"about_ca_topic_score_gemma":0.00005423275,"domain_scores_codex":[0.9949951,0.002347279,0.0006683332,0.0008768702,0.0002960564,0.0008163959],"domain_scores_gemma":[0.9968628,0.0005075745,0.0004654949,0.001764359,0.00007851409,0.0003212381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002095941,0.00004237327,0.001251914,0.002516603,0.0005499004,0.001702595,0.0001025125,9.660795e-7,0.00001515115,0.0001096906,0.009613018,0.9840743],"study_design_scores_gemma":[0.0005468301,0.0002488793,0.002108174,0.007079848,0.0009389849,0.01228349,0.000009459495,0.0000285477,0.000001191547,0.00001147811,0.9764123,0.0003307993],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001001474,0.991698,0.00003097376,0.0009830463,0.0003072431,0.001366554,0.00007873043,0.00008292861,0.004450995],"genre_scores_gemma":[0.0008943859,0.9944791,0.000419449,0.0002129396,0.001656312,0.00006289329,0.0000653418,0.0002170215,0.001992548],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9837435,"threshold_uncertainty_score":0.999882,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1968460841","doi":"10.1016/j.jpedsurg.2011.11.046","title":"Malignant pancreatic tumors in children: a single-institution series","year":2012,"lang":"en","type":"article","venue":"Journal of Pediatric Surgery","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Magnetic resonance imaging; Pancreatectomy; Pancreas; Retrospective cohort study; Radiology; Tuberous sclerosis; Neuroendocrine tumors; Surgery; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.05185917549314155,"gpt":0.2799727355186706,"spread":0.228113560025529,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00171308,0.0001422086,0.0005622988,0.0009696226,0.00004767129,0.0000231303,0.00008445576,0.00007332766,0.0001157887],"category_scores_gemma":[0.001022691,0.00011129,0.0002281504,0.000775429,0.00005847505,0.000513659,0.00003713938,0.0003641392,0.00003533078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002554324,"about_ca_system_score_gemma":0.0004122961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004018758,"about_ca_topic_score_gemma":0.000002935788,"domain_scores_codex":[0.9977816,0.0001475175,0.0007944286,0.000105059,0.0006610752,0.0005102598],"domain_scores_gemma":[0.9986472,0.0003426839,0.0003607399,0.0001718769,0.0001666264,0.0003108833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001892349,0.0004849192,0.9925733,0.00005608259,0.00003675479,0.0001122996,0.0001071175,0.000005646069,0.001299073,0.00002693686,0.003848573,0.001260035],"study_design_scores_gemma":[0.0005314339,0.0001608874,0.9957664,0.0001220912,0.0001213062,0.00220755,0.00007437413,0.000003223696,0.000715913,0.00001996356,0.0001661984,0.0001106551],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950002,0.003761151,0.00004180207,0.0003853249,0.0004375398,0.0001509509,0.000002154366,0.00001588634,0.000204958],"genre_scores_gemma":[0.9942083,0.0007736064,0.0004643053,0.0000720177,0.004388059,0.000003963549,0.000003056618,0.00002054442,0.00006611542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003950519,"threshold_uncertainty_score":0.4538276,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2550532449","doi":"10.1007/s00246-016-1528-y","title":"Accelerated Cardiac Rhabdomyoma Regression with Everolimus in Infants with Tuberous Sclerosis Complex","year":2016,"lang":"en","type":"article","venue":"Pediatric Cardiology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Everolimus; Tuberous sclerosis; Medicine; Rhabdomyoma; Cardiac surgery; Internal medicine; Ventricle; Cardiology; Urology; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.06739486087462356,"gpt":0.2948972194072284,"spread":0.2275023585326048,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005204456,0.0004581976,0.001382061,0.0006582112,0.0001294293,0.00002728557,0.0002987682,0.0002954383,0.0001763894],"category_scores_gemma":[0.0001966439,0.0002481885,0.0001654719,0.001349611,0.0003536504,0.0001682935,0.0002150616,0.000471549,0.0001178782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003640868,"about_ca_system_score_gemma":0.0004005808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003833332,"about_ca_topic_score_gemma":0.0000932434,"domain_scores_codex":[0.9961704,0.0004623834,0.0005194591,0.0009357225,0.0007486844,0.001163371],"domain_scores_gemma":[0.9975498,0.000569195,0.0001550508,0.0009526647,0.0003768925,0.0003964016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002782862,0.00008779852,0.9708667,0.00004755317,0.000207803,0.0003502202,0.00008499407,0.00003942623,0.01198099,0.00001642959,0.004766238,0.008768938],"study_design_scores_gemma":[0.007487757,0.001448746,0.9884714,0.0001560459,0.0002473866,0.0006330615,0.00005076382,0.00003538048,0.0003918273,0.00001386973,0.0006736245,0.0003900761],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947111,0.0007353004,0.0002851789,0.001203046,0.0001667478,0.001056397,0.00005587483,0.0001903461,0.001595991],"genre_scores_gemma":[0.996467,0.001115735,0.0007488219,0.0001701854,0.000930343,0.0002091566,0.0000403966,0.00009437175,0.0002239919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01760471,"threshold_uncertainty_score":0.999997,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2004620932","doi":"10.1007/s00428-007-0378-7","title":"Perivascular epithelioid cell neoplasms (PEComas): four malignant cases expanding the histopathological spectrum and a description of a unique finding","year":2007,"lang":"en","type":"article","venue":"Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Michael's Hospital; Mount Sinai Hospital; University of Toronto; University Health Network","funders":"","keywords":"Pathology; Perivascular Epithelioid Cell; Epithelioid cell; Medicine; Broad spectrum; Biology; Immunohistochemistry; Chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.08407848822791174,"gpt":0.3609627884824356,"spread":0.2768843002545239,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004819438,0.0006919486,0.001355446,0.000602309,0.0005743003,0.00005683858,0.0007411586,0.0004171248,0.00009456949],"category_scores_gemma":[0.002188343,0.0004297467,0.0004549985,0.0007625778,0.002519088,0.0001684111,0.0007774839,0.001706227,0.00003002387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001695473,"about_ca_system_score_gemma":0.0002813732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003195608,"about_ca_topic_score_gemma":0.0000927324,"domain_scores_codex":[0.9941404,0.001046233,0.001268438,0.001209414,0.0008651374,0.001470312],"domain_scores_gemma":[0.9941979,0.003313149,0.0005297532,0.001316683,0.0001521799,0.0004903357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001839634,0.0008174852,0.07483866,0.0004322794,0.0002806597,0.003732803,0.00302093,0.00006154682,0.901811,0.003980694,0.0004457053,0.008738601],"study_design_scores_gemma":[0.00713986,0.008067514,0.7677461,0.0009551279,0.001094765,0.0028055,0.007503649,0.001580384,0.1892491,0.0105109,0.002065762,0.001281415],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810541,0.004073726,0.008820936,0.001517453,0.0002495953,0.001353826,0.00003612085,0.0002093496,0.002684874],"genre_scores_gemma":[0.9875003,0.001965621,0.008985774,0.0007662091,0.0003277531,0.00006536213,0.00006743973,0.00007830881,0.0002432695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.712562,"threshold_uncertainty_score":0.9998154,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2098205962","doi":"10.1111/j.1365-2559.2009.03420.x","title":"Renal epithelioid angiomyolipoma: a study of six cases and a meta‐analytic study. Development of criteria for screening the entity with prognostic significance","year":2009,"lang":"en","type":"review","venue":"Histopathology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; Angiomyolipoma; Atypia; Epithelioid cell; Pathology; Malignancy; Lymph node; Internal medicine; Kidney; Immunohistochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.253091015679408,"gpt":0.419499990263539,"spread":0.166408974584131,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001618638,0.0004433702,0.003466381,0.0004761031,0.0001831476,0.00001431242,0.0003302206,0.0001113413,0.00002963313],"category_scores_gemma":[0.0005715005,0.0002551439,0.0002718578,0.000522036,0.0003700911,0.00003154096,0.0001605618,0.0003306243,0.000001266532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001061795,"about_ca_system_score_gemma":0.0005895965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001110569,"about_ca_topic_score_gemma":0.0006594807,"domain_scores_codex":[0.9964354,0.0008544187,0.001102477,0.0007069976,0.0004999182,0.0004007749],"domain_scores_gemma":[0.9969141,0.001197233,0.0006830831,0.0007275016,0.0003744697,0.0001036537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003820566,0.02742139,0.01495869,0.08285733,0.01826645,0.005075364,0.02739804,0.000007036461,0.001235274,0.000131908,0.0006055821,0.8182223],"study_design_scores_gemma":[0.01728419,0.0862746,0.3122861,0.01496164,0.3884351,0.01168609,0.006575696,0.00004471166,0.00008588615,0.00003428383,0.1597022,0.002629538],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.08754372,0.9015401,0.0006111332,0.00003244297,0.00003022361,0.01014897,0.00005010207,0.0000260773,0.00001724305],"genre_scores_gemma":[0.7345643,0.2177224,0.03721018,0.00006906883,0.0002330195,0.008916351,0.0001255888,0.00028403,0.0008751032],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.8155928,"threshold_uncertainty_score":0.9999901,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4248599381","doi":"10.5858/2009-0637-rsr.1","title":"Epithelioid Angiomyolipoma: A Morphologically Distinct Variant That Mimics a Variety of Intra-abdominal Neoplasms","year":2011,"lang":"en","type":"review","venue":"Archives of Pathology & Laboratory Medicine","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network","funders":"","keywords":"Angiomyolipoma; Pathology; Medicine; Epithelioid cell; Anatomy; Biology; Immunohistochemistry; Kidney; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.08598950653731308,"gpt":0.3341330863155765,"spread":0.2481435797782635,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.001656752,0.001036647,0.006577518,0.001181455,0.0001078424,0.000005887923,0.001163926,0.0007416639,0.0007577628],"category_scores_gemma":[0.001925978,0.0006951927,0.0008295965,0.001170387,0.005845017,0.00006561575,0.0006118249,0.001768199,0.00004343317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008809487,"about_ca_system_score_gemma":0.00168085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009036386,"about_ca_topic_score_gemma":0.00002534215,"domain_scores_codex":[0.9930838,0.00170593,0.002219638,0.001243935,0.0007425092,0.001004211],"domain_scores_gemma":[0.9926835,0.002668029,0.001676263,0.001978836,0.0003943506,0.0005990267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002311904,0.002983551,0.002146627,0.05376146,0.002972699,0.01524061,0.004812098,4.908347e-7,0.0121757,0.00883078,0.002360337,0.8924037],"study_design_scores_gemma":[0.01517905,0.02243288,0.04123206,0.09446341,0.02145915,0.02919057,0.0008073862,0.00007725797,0.0007263645,0.003065219,0.7684283,0.002938309],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004965634,0.986589,0.001931573,0.0002610928,0.0004428215,0.002047302,0.0009298343,0.000103236,0.002729562],"genre_scores_gemma":[0.00532502,0.98072,0.01231592,0.0002384565,0.0004348536,0.0002011393,0.0004366141,0.0001682376,0.0001597834],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8894655,"threshold_uncertainty_score":0.9995499,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1856585084","doi":"10.1186/1471-2490-6-20","title":"Primary PEComa of the bladder treated with primary excision and adjuvant interferon-alpha immunotherapy: a case report","year":2006,"lang":"en","type":"article","venue":"BMC Urology","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Medicine; Cystectomy; Cystoscopy; Laparotomy; Surgery; Malignancy; Dysuria; Alpha interferon; Urinary bladder; Pathology; Radiology; Urinary system; Internal medicine; Bladder cancer; Interferon; Cancer","retraction":null,"screen_n_in":null,"score":{"opus":0.02086071297320231,"gpt":0.2597456239352937,"spread":0.2388849109620914,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003128544,0.0001814531,0.0004406312,0.0001264545,0.00008484451,0.00001031854,0.0001265681,0.0001196885,0.0001192953],"category_scores_gemma":[0.00003769638,0.000107689,0.00007622931,0.0001986838,0.0004551191,0.00004490577,0.0001594331,0.0002683094,0.000004867474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007571749,"about_ca_system_score_gemma":0.0001977223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007589585,"about_ca_topic_score_gemma":0.0005770006,"domain_scores_codex":[0.9984005,0.0002001149,0.0004222108,0.000378498,0.0002802179,0.000318422],"domain_scores_gemma":[0.9986721,0.0002106837,0.0001724298,0.000748849,0.0001339952,0.00006194256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00809287,0.0009446933,0.8164505,0.0001943386,0.0001558657,0.01592326,0.0002979214,0.00002106191,0.1486073,0.0001101435,0.002957585,0.006244493],"study_design_scores_gemma":[0.003149747,0.001712159,0.8985671,0.00001757665,0.00009280185,0.09383975,0.00003129447,0.0001242259,0.001329805,0.00005257569,0.000976713,0.0001062045],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941971,0.001137821,0.0003356331,0.0006905654,0.00004073077,0.0006212379,0.000005300581,0.00004610749,0.002925501],"genre_scores_gemma":[0.9972776,0.000009923131,0.000872318,0.0004218174,0.0000664926,0.0000338352,0.00002677581,0.00004027464,0.001250942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1472774,"threshold_uncertainty_score":0.4391429,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}