{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":102,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":102,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"7c5b8652c8ff","filters":{"venue":"AAPS PharmSciTech"}},"results":[{"id":"W2112281258","doi":"10.1208/pt040107","title":"FIP/AAPS guidelines to dissolution/in vitro release testing of novel/special dosage forms","year":2003,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":370,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Gray (unit); Management; Corporation; Art history; Library science; Humanities; Art; Medicine; Political science; Law; Nuclear medicine; Computer science","authors":[{"name":"Martin Siewert","is_ca":false},{"name":"Jennifer Dressman","is_ca":false},{"name":"Cynthia K. Brown","is_ca":false},{"name":"Vinod P. Shah","is_ca":false},{"name":"Jean-Marc Aiache","is_ca":false},{"name":"Nobuo Aoyagi","is_ca":false},{"name":"Dennis Bashaw","is_ca":false},{"name":"William E. Brown","is_ca":false},{"name":"Diane J. Burgess","is_ca":false},{"name":"John R. Crison","is_ca":false},{"name":"Patrick P. DeLuca","is_ca":false},{"name":"R. A. Djerki","is_ca":false},{"name":"Thomas S. Foster","is_ca":false},{"name":"Kirsti Gjellan","is_ca":false},{"name":"Vivian A. Gray","is_ca":false},{"name":"Ajaz Hussain","is_ca":false},{"name":"Tom Ingallinera","is_ca":false},{"name":"James Klancke","is_ca":false},{"name":"Johannes Kraemer","is_ca":false},{"name":"Henning Gjelstrup Kristensen","is_ca":false},{"name":"Kofi Kumi","is_ca":false},{"name":"C Leuner","is_ca":false},{"name":"Jobst Limberg","is_ca":false},{"name":"Petra Loos","is_ca":false},{"name":"Lenny Margulis","is_ca":false},{"name":"Patrick Marroum","is_ca":false},{"name":"Helga Moeller","is_ca":false},{"name":"Bernd W. Mueller","is_ca":false},{"name":"Martin Mueller‐Zsigmondy","is_ca":false},{"name":"Ngozi Okafo","is_ca":false},{"name":"Larry Ouderkirk","is_ca":false},{"name":"Shravan Parsi","is_ca":false},{"name":"Saeed A. Qureshi","is_ca":true},{"name":"Joseph R. Robinson","is_ca":false},{"name":"Vinod Shah","is_ca":false},{"name":"Ramana Uppoor","is_ca":false},{"name":"Roger Williams","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2134790074663514,"gpt":0.4438465494180014,"spread":0.23036754195165,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009761731,0.002635437,0.001464975,0.007967097,0.003495744,0.002317894,0.005180042,0.006369724,0.01268214],"category_scores_gemma":[0.01602572,0.002058057,0.00312642,0.003393032,0.001885026,0.00156552,0.001945081,0.004382029,0.01999576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001468613,"about_ca_system_score_gemma":0.005649519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01294909,"about_ca_topic_score_gemma":0.02433789,"domain_scores_codex":[0.9816378,0.004670939,0.002952925,0.0005690625,0.009407558,0.0007618701],"domain_scores_gemma":[0.9811642,0.004295616,0.001608721,0.002142899,0.01046759,0.0003210076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008737217,0.001247416,0.001369723,0.005082543,0.0001294275,0.002043535,0.001195312,0.003365326,0.3384487,0.01207567,0.2964106,0.3377579],"study_design_scores_gemma":[0.0001160371,0.0004886279,0.004491574,0.001837905,0.0001535592,0.00276811,0.0003201969,0.002404897,0.1623574,0.003854297,0.8210813,0.0001262917],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.0500003,0.0571916,0.4725693,0.02255907,0.007486507,0.01054444,0.02446018,0.01122057,0.343968],"genre_scores_gemma":[0.08396693,0.0418158,0.643738,0.00827202,0.001841679,0.0116129,0.01959572,0.002824667,0.1863323],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01294909,"threshold_uncertainty_score":0.05162561,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1983612337","doi":"10.1208/s12249-013-0036-0","title":"The Effect of Moisture on the Flowability of Pharmaceutical Excipients","year":2013,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":225,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Microcrystalline cellulose; Materials science; Water content; Carboxymethyl cellulose; Lubricant; Moisture; Starch; Composite material; Chemical engineering; Food science; Chemistry; Cellulose; Organic chemistry","authors":[{"name":"Allison Crouter","is_ca":true},{"name":"Lauren Briens","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06635836512794124,"gpt":0.4085372870469199,"spread":0.3421789219189787,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004309449,0.0003226401,0.0002005864,0.0002297497,0.000225183,0.000311082,0.0002254961,0.0004148073,0.002551784],"category_scores_gemma":[0.00140485,0.0002017911,0.0003530617,0.0002102031,0.0003863802,0.0007054923,0.0002223657,0.0005553973,0.000303289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001850799,"about_ca_system_score_gemma":0.0001425666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007103058,"about_ca_topic_score_gemma":0.00060262,"domain_scores_codex":[0.999587,0.00008085711,0.00004404862,0.00009114805,0.0001142762,0.00008267928],"domain_scores_gemma":[0.9988496,0.00068139,0.0002058576,0.00008233246,0.000127223,0.0000536249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001462888,0.00008209427,0.001799393,0.0001056716,0.00003757571,0.0001313832,0.0001119616,0.0002608239,0.9882338,0.00008484202,0.00007683977,0.007612646],"study_design_scores_gemma":[0.000006685359,0.0004216608,0.003860817,0.000005171872,0.00001961209,0.00004934039,0.00002529984,0.00030634,0.9948271,0.00001537969,0.0004559632,0.000006780103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951479,0.002039474,0.001031201,0.00006882,0.00006343927,0.00002285853,0.0002091318,0.00002825183,0.001388898],"genre_scores_gemma":[0.9980186,0.0005275051,0.0005366403,0.00003336039,0.00002144384,0.000009259657,0.0001038603,0.00001823087,0.0007310633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002551784,"threshold_uncertainty_score":0.008536577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1975257946","doi":"10.1208/s12249-013-0007-5","title":"The Effect of Lubricants on Powder Flowability for Pharmaceutical Application","year":2013,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Granular flow and fluidized beds","field":"Engineering","cited_by":151,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Magnesium stearate; Materials science; Stearic acid; Lubricant; Stearate; Lactose; Magnesium; Chlorpheniramine Maleate; Dosage form; Chemical engineering; Composite material; Chromatography; Chemistry; Metallurgy; Organic chemistry","authors":[{"name":"Garett Morin","is_ca":true},{"name":"Lauren Briens","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00700114255151391,"gpt":0.2585904266001156,"spread":0.2515892840486016,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000581844,0.0002987831,0.0003488677,0.0003706591,0.0003329758,0.0007543478,0.0002276388,0.0003399324,0.001181946],"category_scores_gemma":[0.001796892,0.0002113825,0.00041823,0.0003316759,0.0003717136,0.0007335142,0.0002676053,0.0003511755,0.0002035719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002947668,"about_ca_system_score_gemma":0.0003665812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001327305,"about_ca_topic_score_gemma":0.001288345,"domain_scores_codex":[0.9995874,0.0001052027,0.00005163848,0.00004387666,0.000127625,0.00008438547],"domain_scores_gemma":[0.9991012,0.0005121796,0.0001533049,0.00003696572,0.000137245,0.00005919906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003792278,0.0001642474,0.002021551,0.000306959,0.0000474266,0.000190318,0.0001335285,0.001331332,0.9725454,0.0002948706,0.00009700146,0.01907512],"study_design_scores_gemma":[0.00002230688,0.001483323,0.003277545,0.000008965113,0.00004846503,0.0000679195,0.00004185205,0.001753199,0.992564,0.00003932645,0.0006809711,0.00001200594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952122,0.003178844,0.0009204614,0.00004398065,0.00002665278,0.00001183954,0.00005037576,0.00002066633,0.0005349289],"genre_scores_gemma":[0.9975429,0.001139269,0.0008363162,0.00001503488,0.00001132139,0.000003954496,0.00006080742,0.00001246397,0.0003780595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001327305,"threshold_uncertainty_score":0.003954053,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2009029384","doi":"10.1208/pt040454","title":"Aerodynamic particle size analysis of aerosols from pressurized metered-dose inhalers: Comparison of andersen 8-stage cascade impactor, next generation pharmaceutical impactor, and model 3321 aerodynamic particle sizer aerosol spectrometer","year":2003,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Aerosol; Geometric standard deviation; Aerodynamic diameter; Particle size; Metered-dose inhaler; Dry-powder inhaler; Particle-size distribution; Chemistry; Particle (ecology); Fluticasone propionate; Beclometasone dipropionate; Inhaler; Radiochemistry; Materials science; Analytical Chemistry (journal); Chromatography; Inhalation; Medicine; Lung; Organic chemistry; Asthma","authors":[{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Mark Nagel","is_ca":true},{"name":"Kimberly J. Wiersema","is_ca":true},{"name":"Cathy Doyle","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09697337607251257,"gpt":0.3642616703969924,"spread":0.2672882943244798,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001019095,0.0002977318,0.0004056498,0.0009683514,0.0004570656,0.0003212628,0.0005063626,0.0005538648,0.001125755],"category_scores_gemma":[0.001539831,0.0002917592,0.0003474645,0.0003534799,0.000246876,0.0005597317,0.0003456982,0.0003788025,0.0002953395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003452749,"about_ca_system_score_gemma":0.0004087984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003179153,"about_ca_topic_score_gemma":0.004244629,"domain_scores_codex":[0.9991329,0.0001155273,0.00006423432,0.0001136163,0.0005316452,0.00004206616],"domain_scores_gemma":[0.9989047,0.0004744755,0.00008181991,0.00005511185,0.0004092496,0.00007465441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002560251,0.0002208561,0.04054839,0.0002598343,0.0001220797,0.0001571381,0.0003413412,0.000621307,0.8945956,0.0003390827,0.0006698866,0.05956423],"study_design_scores_gemma":[0.0001028615,0.002919823,0.2886808,0.00001947613,0.0001493366,0.001328999,0.0002358387,0.01043013,0.6928352,0.0001936472,0.003043008,0.00006105455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736181,0.002165452,0.0196455,0.0001375577,0.0000891612,0.0002218248,0.0007198591,0.0003591811,0.003043418],"genre_scores_gemma":[0.9736495,0.001402461,0.02044316,0.0001655891,0.00005249379,0.00007776205,0.0009219839,0.00007313622,0.003213938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003179153,"threshold_uncertainty_score":0.006321311,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1973393008","doi":"10.1208/s12249-008-9060-x","title":"Effect of Drug Solubility on Polymer Hydration and Drug Dissolution from Polyethylene Oxide (PEO) Matrix Tablets","year":2008,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":104,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Solubility; Dissolution; Polyethylene oxide; Drug; Polymer; Chemistry; Matrix (chemical analysis); Chemical engineering; Polyethylene; Materials science; Organic chemistry; Chromatography; Pharmacology; Medicine","authors":[{"name":"Hongtao Li","is_ca":true},{"name":"Robert J. Hardy","is_ca":true},{"name":"Xiaochen Gu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03722234705613126,"gpt":0.3726687105876328,"spread":0.3354463635315015,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004836628,0.0002946673,0.0003035522,0.0001815971,0.0001955542,0.0003027086,0.0001698332,0.0002261983,0.001838578],"category_scores_gemma":[0.001472443,0.0002900864,0.0003206872,0.0002019965,0.0003246376,0.0006826899,0.0002401425,0.000521145,0.0003280922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001979721,"about_ca_system_score_gemma":0.0003094507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001009958,"about_ca_topic_score_gemma":0.001162109,"domain_scores_codex":[0.9996898,0.0000827996,0.0000448301,0.00004603519,0.00007219988,0.00006439124],"domain_scores_gemma":[0.9990251,0.0006513821,0.0001311993,0.00004431388,0.00007270411,0.00007528648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008243103,0.0003127917,0.001217209,0.0001717637,0.00003747676,0.0002463724,0.0002292056,0.0005107668,0.9821249,0.0000971278,0.0001170253,0.006692114],"study_design_scores_gemma":[0.0000449473,0.001315235,0.002765286,0.000004514656,0.00002818659,0.00006062914,0.00001976078,0.001460226,0.993996,0.00001026112,0.0002886351,0.000006304555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978964,0.000542562,0.0005984415,0.00003484719,0.00001694124,0.00002690724,0.00008640513,0.00003326741,0.0007641376],"genre_scores_gemma":[0.9976973,0.0003361671,0.000803403,0.00002022978,0.0000189491,0.00001265735,0.0001024543,0.00002628916,0.0009826701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001838578,"threshold_uncertainty_score":0.006150603,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044941780","doi":"10.1208/pt0804110","title":"In vitro and in vivo aspects of cascade impactor tests and inhaler performance: A review","year":2007,"lang":"en","type":"review","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Inhaler; Cascade impactor; Bioequivalence; Medicine; Respiratory tract; Computer science; Particle size; Intensive care medicine; Asthma; Pharmacology; Respiratory system; Chemistry; Internal medicine; Pharmacokinetics","authors":[{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Steve Newman","is_ca":false},{"name":"Hak‐Kim Chan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0516998025305349,"gpt":0.3814398716983147,"spread":0.3297400691677798,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001502984,0.001792109,0.003898597,0.003581965,0.0002961165,0.001187288,0.001771134,0.001411238,0.002226763],"category_scores_gemma":[0.001618358,0.0005407708,0.001090431,0.00364416,0.0006181449,0.001505961,0.0005706531,0.0009011574,0.001989581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004883019,"about_ca_system_score_gemma":0.001145415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00139816,"about_ca_topic_score_gemma":0.002179028,"domain_scores_codex":[0.9991291,0.0001117967,0.0001187856,0.0001260398,0.0004717029,0.00004264515],"domain_scores_gemma":[0.9982948,0.0009972465,0.000195837,0.0000451369,0.0004304156,0.00003651966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000167852,0.0002838887,0.0004895511,0.02668253,0.0001284432,0.000386572,0.00008427077,0.0005614086,0.02075718,0.0006868984,0.006037328,0.9437341],"study_design_scores_gemma":[0.00007191514,0.001527365,0.00637923,0.007380499,0.001204025,0.005735019,0.0004062125,0.0006846206,0.05052716,0.001689281,0.9242195,0.0001750872],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006332793,0.9973831,0.0008384649,0.0000839168,0.0001112111,0.00001765721,0.00004592074,0.00001220665,0.0008742322],"genre_scores_gemma":[0.001779048,0.9962565,0.0009797108,0.0000744413,0.0001030193,0.00001927735,0.00005780909,0.000003795501,0.0007264762],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003898597,"threshold_uncertainty_score":0.007948697,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2001838193","doi":"10.1208/s12249-012-9822-3","title":"Challenges with Developing In Vitro Dissolution Tests for Orally Inhaled Products (OIPs)","year":2012,"lang":"en","type":"review","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Dissolution; Dissolution testing; Biochemical engineering; Flow properties; Risk analysis (engineering); Computer science; Medicine; Pharmacology; Process engineering; Nanotechnology; Materials science; Engineering; Chemical engineering; Physics","authors":[{"name":"Trevor Riley","is_ca":false},{"name":"David Christopher","is_ca":false},{"name":"Jan Arp","is_ca":false},{"name":"Andrea Casazza","is_ca":false},{"name":"Agnes Colombani","is_ca":false},{"name":"Andrew Cooper","is_ca":false},{"name":"Monisha Dey","is_ca":false},{"name":"Janet Maas","is_ca":false},{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Maria Reiners","is_ca":false},{"name":"Nastaran Sigari","is_ca":false},{"name":"Terrence P. Tougas","is_ca":false},{"name":"Svetlana Lyapustina","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2017367041524933,"gpt":0.3922449231509652,"spread":0.190508218998472,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01476577,0.001490142,0.003301482,0.002882758,0.000549652,0.003756131,0.002920761,0.002523309,0.002694816],"category_scores_gemma":[0.01584381,0.001066158,0.001496792,0.001698925,0.001463591,0.00321415,0.001423565,0.004093554,0.003302179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008881577,"about_ca_system_score_gemma":0.002786732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002717243,"about_ca_topic_score_gemma":0.005046319,"domain_scores_codex":[0.9884894,0.003191465,0.001313963,0.0008207675,0.005847556,0.0003367325],"domain_scores_gemma":[0.9742381,0.01441787,0.002166411,0.0009459253,0.00785967,0.0003720317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002234447,0.0005358051,0.001706728,0.02178061,0.0002207943,0.0005287076,0.0004701937,0.001123047,0.1353429,0.00367791,0.01439337,0.8199965],"study_design_scores_gemma":[0.00007048908,0.002184612,0.007123271,0.005105356,0.0005281423,0.005137927,0.001417711,0.002538127,0.2130339,0.003960958,0.7587183,0.0001811129],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01326058,0.9112855,0.04662449,0.005968313,0.001874458,0.0006662799,0.0008856705,0.0003764539,0.01905832],"genre_scores_gemma":[0.06132371,0.8092534,0.1117608,0.003179092,0.001445376,0.0005786357,0.001329026,0.0001831073,0.01094699],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01476577,"threshold_uncertainty_score":0.07808977,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2085478646","doi":"10.1208/s12249-011-9620-3","title":"Effects of Spray Drying on Physicochemical Properties of Chitosan Acid Salts","year":2011,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Nanocomposite Films for Food Packaging","field":"Materials Science","cited_by":80,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre for Drug Research and Development","funders":"Helsingin Yliopisto","keywords":"Chitosan; Chemistry; Fourier transform infrared spectroscopy; Acetic acid; Spray drying; Nuclear chemistry; Differential scanning calorimetry; Citric acid; Solvent; Infrared spectroscopy; Organic chemistry; Chemical engineering","authors":[{"name":"Mirna Fernández Cervera","is_ca":false},{"name":"Jyrki Heinämäki","is_ca":false},{"name":"Nilia de la Paz","is_ca":true},{"name":"Sirkka Liisa Maunu","is_ca":false},{"name":"Tommi Virtanen","is_ca":false},{"name":"Timo Hatanpää","is_ca":false},{"name":"Osmo Antikainen","is_ca":false},{"name":"Nogueira Antonio","is_ca":true},{"name":"Jorge Fundora","is_ca":false},{"name":"Jouko Yliruusi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02216062649290038,"gpt":0.2292235732607649,"spread":0.2070629467678645,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003110132,0.0003904108,0.000256192,0.000176231,0.0001658116,0.0002172346,0.0001743208,0.0003261396,0.00176714],"category_scores_gemma":[0.0007284234,0.0002439319,0.0003220467,0.0002230886,0.0002580458,0.0003377705,0.0001198306,0.0005508946,0.0002461592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002211921,"about_ca_system_score_gemma":0.0002313496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220257,"about_ca_topic_score_gemma":0.001876652,"domain_scores_codex":[0.9998116,0.00002106061,0.00002608975,0.00003426092,0.00006002849,0.00004698637],"domain_scores_gemma":[0.9994397,0.0002656899,0.00008583083,0.00003921603,0.0001235072,0.00004608692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003184918,0.00002344914,0.0001380502,0.00004083037,0.00000727713,0.00005452978,0.00003072471,0.00005123845,0.9981197,0.00001605439,0.00002345294,0.001176117],"study_design_scores_gemma":[0.00001069503,0.0001827778,0.001278865,0.000002526828,0.00001172035,0.00003895547,0.00001316548,0.0002241047,0.9980024,0.00000489092,0.000225578,0.000004262849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970125,0.001138406,0.0008306218,0.00003416122,0.0000469996,0.00001569771,0.00009207306,0.00002937667,0.0008002082],"genre_scores_gemma":[0.9963499,0.0009350525,0.001262285,0.00006116722,0.00001746791,0.00001189975,0.0001563089,0.00003622224,0.001169615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00176714,"threshold_uncertainty_score":0.005911648,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2104009433","doi":"10.1208/s12249-014-0189-5","title":"Intranasal Drug Delivery of Olanzapine-Loaded Chitosan Nanoparticles","year":2014,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":77,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Bioavailability; Nasal administration; Chitosan; Chemistry; Pharmacology; Olanzapine; Absorption (acoustics); Drug delivery; Nanoparticle; Systemic administration; In vivo; Chromatography; Medicine; Materials science; Nanotechnology; Organic chemistry","authors":[{"name":"Sarah Baltzley","is_ca":false},{"name":"Mohammad Atiquzzaman","is_ca":true},{"name":"Ahmad H. Malkawi","is_ca":false},{"name":"Abeer M. Al-Ghananeem","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05590672016217323,"gpt":0.3782277501574421,"spread":0.3223210299952689,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100906,0.0003419701,0.0001699831,0.0001461158,0.0001409695,0.000194459,0.0001769537,0.0003017595,0.0009949906],"category_scores_gemma":[0.0001045249,0.0001078785,0.0002406376,0.00009175602,0.000138356,0.0002235476,0.0001325001,0.0003239784,0.0002542919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004321219,"about_ca_system_score_gemma":0.0003872588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003569039,"about_ca_topic_score_gemma":0.005189297,"domain_scores_codex":[0.9999127,0.000006855752,0.00000672124,0.00002146023,0.00002086366,0.00003134603],"domain_scores_gemma":[0.9999437,0.000009193511,0.00001695147,0.000003925644,0.00001287189,0.00001336924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002283569,0.00003031264,0.00005992665,0.00005087218,0.00000528481,0.00008449216,0.0000148913,0.00008604825,0.996549,0.00004908243,0.00008046612,0.002761342],"study_design_scores_gemma":[0.00003188703,0.0006445715,0.001038426,0.000004927321,0.00002792551,0.00009432601,0.00001897547,0.001342512,0.9955871,0.0000127708,0.001187818,0.000008705475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935849,0.001088916,0.002229842,0.0001149148,0.0001024735,0.00006130581,0.0001549539,0.00009383578,0.002568892],"genre_scores_gemma":[0.9938926,0.0005484931,0.002047511,0.00005114105,0.00001688319,0.00003284048,0.00009561296,0.00001411351,0.003300966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003569039,"threshold_uncertainty_score":0.007096529,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1979373797","doi":"10.1208/pt070241","title":"Fast-disintegrating sublingual tablets: Effect of epinephrine load on tablet characteristics","year":2006,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; University of Manitoba","funders":"Manitoba Health Research Council","keywords":"Friability; Microcrystalline cellulose; Wetting; Hydroxypropyl cellulose; Materials science; Sublingual administration; Dosage form; Composite material; Compression (physics); Excipient; Chromatography; Chemistry; Cellulose; Pharmacology; Medicine; Ethyl cellulose; Organic chemistry; Polymer","authors":[{"name":"Mutasem Rawas‐Qalaji","is_ca":true},{"name":"F. Estelle","is_ca":true},{"name":"Richard Simons","is_ca":true},{"name":"Keith J. Simons","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01016925729897246,"gpt":0.29824357527798,"spread":0.2880743179790076,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004918208,0.00036452,0.000435868,0.000278534,0.000178766,0.0004460908,0.0002067798,0.0004507377,0.002148326],"category_scores_gemma":[0.002944685,0.0002591429,0.0003820843,0.0003213903,0.0002101382,0.0009615769,0.0002049664,0.0003900147,0.0004003818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001387632,"about_ca_system_score_gemma":0.0002045602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007005993,"about_ca_topic_score_gemma":0.0006329559,"domain_scores_codex":[0.9995977,0.0001125525,0.00005716158,0.00006736308,0.0001055258,0.00005960167],"domain_scores_gemma":[0.9973677,0.001940153,0.0002500232,0.0001113164,0.0001516149,0.0001792187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.06944342,0.0009323296,0.004862399,0.0003244033,0.00009217032,0.0002756262,0.0003495523,0.0009092543,0.8798445,0.00005730101,0.0003063027,0.04260279],"study_design_scores_gemma":[0.0008664634,0.02329491,0.06680519,0.00002304614,0.0003181158,0.0005314694,0.0001364473,0.004982293,0.9016014,0.00005043778,0.001330019,0.00006002632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974794,0.001102774,0.0006775119,0.0000371455,0.0000288798,0.00004921473,0.0001531629,0.00003434896,0.0004375587],"genre_scores_gemma":[0.9970593,0.0007023755,0.001130726,0.00005603545,0.00003611367,0.00002678552,0.0002149677,0.00004642193,0.0007271349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002148326,"threshold_uncertainty_score":0.00718689,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1995557581","doi":"10.1208/s12249-011-9644-8","title":"Radiation and Ethylene Oxide Terminal Sterilization Experiences with Drug Eluting Stent Products","year":2011,"lang":"en","type":"review","venue":"AAPS PharmSciTech","topic":"Medical Device Sterilization and Disinfection","field":"Immunology and Microbiology","cited_by":71,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Abbott (Canada)","funders":"","keywords":"Sterilization (economics); Medical device; Process engineering; Computer science; Medicine; Biomedical engineering; Business; Engineering","authors":[{"name":"Byron J. Lambert","is_ca":true},{"name":"Todd A. Mendelson","is_ca":true},{"name":"Michael Craven","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0359704780312096,"gpt":0.3017537666964177,"spread":0.2657832886652081,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009565513,0.0008299944,0.0008938718,0.001546716,0.0002841341,0.0007259813,0.0007803861,0.001134488,0.002121486],"category_scores_gemma":[0.0008359561,0.0002538033,0.0004753692,0.001476011,0.0005286638,0.001176326,0.0004320732,0.00100905,0.0009784284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004096307,"about_ca_system_score_gemma":0.0007568547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007334446,"about_ca_topic_score_gemma":0.001825198,"domain_scores_codex":[0.9996923,0.00005080616,0.00003939821,0.00005371336,0.000137669,0.00002613901],"domain_scores_gemma":[0.9995522,0.0002426555,0.00007303205,0.00001345991,0.00009204801,0.00002648206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009993674,0.0001343164,0.0004049593,0.008646132,0.00005408342,0.0004848572,0.0001113465,0.0002149982,0.004445918,0.0009374255,0.01243586,0.9720303],"study_design_scores_gemma":[0.0000378283,0.0007163256,0.004744746,0.003648856,0.000208437,0.009765599,0.0002352836,0.0001369318,0.006440985,0.001152387,0.9728627,0.00004990589],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005375331,0.9982401,0.000123477,0.0000948374,0.00009872916,0.00000343262,0.000004142544,0.000003339406,0.0008943741],"genre_scores_gemma":[0.001879806,0.9965376,0.0002133654,0.0001523117,0.0001888956,0.00000491611,0.00001450016,0.000001858823,0.001006827],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002121486,"threshold_uncertainty_score":0.007097065,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2904241152","doi":"10.1208/s12249-018-1244-4","title":"Solubility Prediction of Drugs in Binary Solvent Mixtures at Various Temperatures Using a Minimum Number of Experimental Data Points","year":2018,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Crystallization and Solubility Studies","field":"Materials Science","cited_by":61,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"CNIB","keywords":"Solubility; Outlier; Data point; Binary number; Solvent; Mathematics; Statistics; Chemistry; Thermodynamics; Computer science; Organic chemistry; Physics; Arithmetic","authors":[{"name":"Sina Dadmand","is_ca":false},{"name":"Farzin Kamari","is_ca":false},{"name":"William E. Acree","is_ca":false},{"name":"Abolghasem Jouyban","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05039244259021514,"gpt":0.3460640688888448,"spread":0.2956716262986296,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007879197,0.0007281184,0.0006977282,0.0005639943,0.0003660217,0.0003954589,0.0004747004,0.0005622121,0.000897094],"category_scores_gemma":[0.002120897,0.000379689,0.0008656382,0.0004949472,0.0003004582,0.0008240062,0.0003135196,0.0007072823,0.0005398336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005421216,"about_ca_system_score_gemma":0.0007652992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002395155,"about_ca_topic_score_gemma":0.003070267,"domain_scores_codex":[0.9995586,0.00005470592,0.00005406811,0.000107346,0.0001891561,0.00003607395],"domain_scores_gemma":[0.9992655,0.0003121881,0.0001269005,0.0000598296,0.0002148277,0.00002079227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001898814,0.0003855783,0.006266278,0.0005455242,0.0000779584,0.0001241502,0.00007651415,0.06596123,0.899069,0.0006373562,0.0005818969,0.02437571],"study_design_scores_gemma":[0.00003679461,0.0004345702,0.00449801,0.00001528176,0.00004209569,0.00006940201,0.0000260031,0.1772747,0.8165781,0.0002494036,0.0007477818,0.00002775073],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9130017,0.0008058336,0.08125599,0.0001574414,0.0000383127,0.0001676737,0.001875128,0.0005877645,0.002110266],"genre_scores_gemma":[0.9516813,0.0005201314,0.0444758,0.00002801229,0.00000693407,0.0002037799,0.002039071,0.00008328637,0.0009616832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002395155,"threshold_uncertainty_score":0.004762411,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4229451525","doi":"10.1208/s12249-022-02294-w","title":"Optimization of DOTAP/chol Cationic Lipid Nanoparticles for mRNA, pDNA, and Oligonucleotide Delivery","year":2022,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Carleton University","funders":"National Institute of General Medical Sciences; Binghamton University; National Institutes of Health","keywords":"Transfection; PEGylation; Chemistry; Oligonucleotide; Nucleic acid; Gene delivery; Messenger RNA; Molecular biology; Biophysics; Biochemistry; Biology; Gene","authors":[{"name":"Mengwei Sun","is_ca":false},{"name":"Utkarsh J. Dang","is_ca":true},{"name":"Yuhao Yuan","is_ca":false},{"name":"Alexandra Maria Psaras","is_ca":false},{"name":"Ositomiwa O. Osipitan","is_ca":false},{"name":"Tracy A. Brooks","is_ca":false},{"name":"Fake Lu","is_ca":false},{"name":"Anthony J. Di Pasqua","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01172467703047005,"gpt":0.2463721332121306,"spread":0.2346474561816605,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005100408,0.0005095561,0.0003625491,0.0002387076,0.0002779976,0.0004308349,0.0002329099,0.0003682837,0.0005738463],"category_scores_gemma":[0.0003793312,0.0002533022,0.0002817089,0.0002553818,0.0002215283,0.0002547816,0.000259498,0.0003703435,0.0003755097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007256672,"about_ca_system_score_gemma":0.0004952472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001595905,"about_ca_topic_score_gemma":0.003435824,"domain_scores_codex":[0.9996138,0.00005227099,0.00004939846,0.00008058453,0.0001400342,0.00006392935],"domain_scores_gemma":[0.9998404,0.00003449073,0.00002724765,0.00001120517,0.00006442568,0.00002214002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005441091,0.0000235877,0.00005618733,0.00004094937,0.000004134482,0.00002206299,0.0000165319,0.0004546809,0.998069,0.00007538655,0.00002755857,0.001155525],"study_design_scores_gemma":[0.000006168589,0.00007328711,0.0001793502,0.000001885504,0.0000069167,0.00001988585,0.00000723333,0.001340755,0.9977034,0.00001114113,0.0006459104,0.000004044742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764374,0.0006791813,0.02027928,0.00009199779,0.00003624078,0.0002306423,0.000208459,0.0001360212,0.001900802],"genre_scores_gemma":[0.9574093,0.0007978748,0.03734105,0.0000669769,0.000009718848,0.0003262314,0.0004190726,0.0001241802,0.003505591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001595905,"threshold_uncertainty_score":0.005265117,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2048735220","doi":"10.1208/s12249-010-9402-3","title":"An Electronic Tongue: Evaluation of the Masking Efficacy of Sweetening and/or Flavoring Agents on the Bitter Taste of Epinephrine","year":2010,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Biochemical Analysis and Sensing Techniques","field":"Nursing","cited_by":59,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; University of Manitoba","funders":"Pfizer Canada; University of Manitoba; Manitoba Health Research Council; Pfizer","keywords":"Electronic tongue; Sweetening; Taste; Tongue; Sweetening agents; Masking (illustration); Epinephrine; Taste disorder; Chemistry; Bitter taste; Pharmacology; Anesthesia; Medicine; Food science","authors":[{"name":"Ousama Rachid","is_ca":true},{"name":"F. Estelle R. Simons","is_ca":true},{"name":"Mutasem Rawas-Qalaji","is_ca":false},{"name":"Keith J. Simons","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03412762610294855,"gpt":0.3354780970918144,"spread":0.3013504709888658,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000689677,0.0004779728,0.0002886318,0.0002063404,0.0002674604,0.0002220049,0.0002898153,0.0005247131,0.002753507],"category_scores_gemma":[0.001352303,0.0002601956,0.0003719559,0.0002174609,0.0004124034,0.0005116721,0.0003461618,0.0004084518,0.0002677438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000116885,"about_ca_system_score_gemma":0.0003847928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007491665,"about_ca_topic_score_gemma":0.0007130828,"domain_scores_codex":[0.9996719,0.0001155144,0.00003262564,0.00004467825,0.00007910724,0.00005605746],"domain_scores_gemma":[0.9993054,0.0003751219,0.00008875613,0.00004858858,0.00008729695,0.00009485263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03227974,0.001592517,0.003531497,0.0002980368,0.00004466272,0.0006636913,0.0003006383,0.0001780291,0.941865,0.0001312788,0.0000930219,0.01902179],"study_design_scores_gemma":[0.001216917,0.1424631,0.05557644,0.0000325679,0.000498467,0.002053573,0.0006705532,0.003221593,0.792686,0.00009799872,0.001434708,0.0000480188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984219,0.000345478,0.0005810813,0.00002285383,0.00003255261,0.00005258564,0.00002856483,0.000006972623,0.000507932],"genre_scores_gemma":[0.995434,0.0007074786,0.002203631,0.000066162,0.00003860329,0.00004176718,0.00006193971,0.000008383187,0.001438086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002753507,"threshold_uncertainty_score":0.009211361,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016781414","doi":"10.1208/pt050111","title":"Phospholipid-stabilized nanoparticles of cyclosporine a by rapid expansion from supercritical to aqueous solution","year":2004,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":56,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BioPhage Pharma (Canada)","funders":"Division of Chemistry; National Science Foundation","keywords":"Dynamic light scattering; Supercritical fluid; Aqueous solution; Particle size; Pulmonary surfactant; Solubility; Particle (ecology); Nanoparticle; Chemical engineering; Chromatography; Particle-size distribution; Dissolution; Chemistry; Micelle; Materials science; Transmission electron microscopy; Nanotechnology; Organic chemistry","authors":[{"name":"Timothy J. Young","is_ca":false},{"name":"Keith P. Johnston","is_ca":false},{"name":"Gary W. Pace","is_ca":true},{"name":"Awadhesh Kumar Mishra","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009070386301695944,"gpt":0.2415226558027779,"spread":0.2324522695010819,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000156546,0.0002562272,0.0001299053,0.0001569204,0.000134057,0.0001867753,0.0001195221,0.0002121583,0.0007088083],"category_scores_gemma":[0.0001410499,0.0001327383,0.0001655214,0.00009083591,0.0001588198,0.0002797393,0.000202124,0.0003964884,0.0003444292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002800593,"about_ca_system_score_gemma":0.000236976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006499995,"about_ca_topic_score_gemma":0.001124032,"domain_scores_codex":[0.9999225,0.00000899646,0.000006979847,0.00001793117,0.00002602326,0.00001758657],"domain_scores_gemma":[0.9999384,0.00001385234,0.000015941,0.00000664666,0.00001402848,0.00001104714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003483419,0.000004916625,0.00001938787,0.00001297801,0.000001977997,0.00001199245,0.00001013079,0.00009042327,0.9987617,0.00006650901,0.00002717934,0.0009579103],"study_design_scores_gemma":[0.000008356837,0.00004934521,0.0001617755,0.000001648296,0.000004460045,0.0000197488,0.000003326229,0.0005327961,0.9984952,0.00001514445,0.0007062627,0.000001913089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830678,0.001015612,0.0107066,0.0001698835,0.00006262562,0.00006494273,0.0001147662,0.0001895501,0.004608134],"genre_scores_gemma":[0.9933414,0.0004055811,0.003110552,0.00004596846,0.00001253946,0.00003322108,0.000101706,0.00003921297,0.00290979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007088083,"threshold_uncertainty_score":0.002371252,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016303028","doi":"10.1208/s12249-008-9175-0","title":"Formulation of Sustained-Release Dosage Form of Verapamil Hydrochloride by Solid Dispersion Technique Using Eudragit RLPO or Kollidon®SR","year":2009,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":54,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Royal College of Physicians and Surgeons of Canada","funders":"","keywords":"Dosage form; Chemistry; Differential scanning calorimetry; Chromatography; Solubility; Dispersion (optics); Fourier transform infrared spectroscopy; Polymer; Dissolution; Nuclear chemistry; Chemical engineering; Organic chemistry","authors":[{"name":"Jagannath Sahoo","is_ca":true},{"name":"P. N. Murthy","is_ca":true},{"name":"S. Biswal","is_ca":true},{"name":"Manik","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06747040006436747,"gpt":0.4102480138007174,"spread":0.34277761373635,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003721111,0.0003451866,0.0005731903,0.0003079192,0.0001887098,0.0003235392,0.0004031367,0.0004528649,0.001313684],"category_scores_gemma":[0.0002847855,0.0001922469,0.0003594244,0.0001754399,0.0001687136,0.0003804727,0.0002129229,0.0007034544,0.0006944527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760965,"about_ca_system_score_gemma":0.0001928756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002276712,"about_ca_topic_score_gemma":0.0003490506,"domain_scores_codex":[0.9997978,0.00002390984,0.00003386666,0.00005028525,0.0000686613,0.00002554084],"domain_scores_gemma":[0.9998755,0.00002914486,0.0000390459,0.00001739649,0.0000254375,0.0000134686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002504861,0.0001103866,0.00006311021,0.0001543059,0.00002152475,0.0001319741,0.00004449221,0.0001409765,0.9855698,0.0001818088,0.0001436588,0.01318751],"study_design_scores_gemma":[0.0001516694,0.002218297,0.0006426465,0.00001395929,0.00008672426,0.0003366421,0.00001322414,0.001306739,0.9900352,0.0000559524,0.005126733,0.00001223599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9196967,0.005934435,0.06702689,0.0004339465,0.0004570684,0.0007156725,0.0006619649,0.0006654456,0.004407812],"genre_scores_gemma":[0.9352466,0.003320646,0.049222,0.0001543184,0.0001529522,0.0005251007,0.0006502942,0.0001182105,0.01060991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001313684,"threshold_uncertainty_score":0.00439471,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016824776","doi":"10.1208/s12249-014-0205-9","title":"Probucol Release from Novel Multicompartmental Microcapsules for the Oral Targeted Delivery in Type 2 Diabetes","year":2014,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":48,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"Curtin University of Technology","keywords":"Swelling; Chemistry; Zeta potential; Chromatography; Drug delivery; Controlled release; Sodium alginate; Pharmacology; Chemical engineering; Materials science; Sodium; Nanotechnology; Nanoparticle; Organic chemistry; Medicine","authors":[{"name":"Armin Mooranian","is_ca":false},{"name":"Rebecca Negrulj","is_ca":false},{"name":"Hesham Al‐Sallami","is_ca":false},{"name":"Zhongxiang Fang","is_ca":false},{"name":"Momir Mikov","is_ca":false},{"name":"Svetlana Goločorbin-Kon","is_ca":false},{"name":"Marc Fakhoury","is_ca":true},{"name":"Gerald F. Watts","is_ca":false},{"name":"Vance B. Matthews","is_ca":false},{"name":"Frank Arfuso","is_ca":false},{"name":"Amanda Lambros","is_ca":false},{"name":"Hani Al‐Salami","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08985804007886793,"gpt":0.3896161416758223,"spread":0.2997581015969544,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001792162,0.0002489668,0.0002616058,0.0001697731,0.0001627898,0.000308964,0.0001925267,0.0002924711,0.0004860527],"category_scores_gemma":[0.0002086928,0.0001562816,0.0002610678,0.0001115364,0.000147381,0.0003858169,0.0002218841,0.0003498731,0.0002426068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003606885,"about_ca_system_score_gemma":0.0002728311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000903498,"about_ca_topic_score_gemma":0.001032193,"domain_scores_codex":[0.9998842,0.00001873481,0.00001086855,0.00003028387,0.00002915195,0.00002669812],"domain_scores_gemma":[0.9999357,0.00001558963,0.00001831356,0.000005958166,0.00001269752,0.00001160095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002869421,0.00005100674,0.000134518,0.0001051366,0.00001048242,0.0001255959,0.00004283042,0.0006431257,0.9874565,0.0001156748,0.0001221916,0.01090588],"study_design_scores_gemma":[0.00002415927,0.0003911761,0.0007706362,0.000007014929,0.00003047478,0.000174493,0.00001522297,0.002683011,0.9942487,0.00001959196,0.001622684,0.00001281526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853659,0.004478572,0.008708448,0.0001292001,0.00006753982,0.00004067154,0.00009669173,0.0001027993,0.001010178],"genre_scores_gemma":[0.9890957,0.001756941,0.005828217,0.00005135276,0.00002071529,0.00005574322,0.00007217927,0.00002931165,0.003089712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000903498,"threshold_uncertainty_score":0.002616942,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1976817464","doi":"10.1208/s12249-008-9045-9","title":"Minimizing Variability of Cascade Impaction Measurements in Inhalers and Nebulizers","year":2008,"lang":"en","type":"review","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Quality by Design; Computer science; Quality (philosophy); Risk analysis (engineering); Process engineering; Biochemical engineering; Medicine; Aerosol; Environmental science; Reliability engineering; Particle size; Chemistry; Engineering; Physics","authors":[{"name":"Matthew Bonam","is_ca":false},{"name":"David Christopher","is_ca":false},{"name":"David Cipolla","is_ca":false},{"name":"Brent Donovan","is_ca":false},{"name":"David A. Goodwin","is_ca":false},{"name":"Susan Holmes","is_ca":false},{"name":"Svetlana Lyapustina","is_ca":false},{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Steve Nichols","is_ca":false},{"name":"Gunilla Pettersson","is_ca":false},{"name":"Chris Quale","is_ca":false},{"name":"Nagaraja Rao","is_ca":false},{"name":"Dilraj Singh","is_ca":false},{"name":"Terrence P. Tougas","is_ca":false},{"name":"Mike Van Oort","is_ca":false},{"name":"Bernd Walther","is_ca":false},{"name":"Bruce Wyka","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1331558775492644,"gpt":0.3887463571086612,"spread":0.2555904795593968,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006375618,0.001212259,0.002526986,0.003976683,0.0003063015,0.001020125,0.001577735,0.001240621,0.001195],"category_scores_gemma":[0.009936747,0.0006362704,0.00182733,0.002997723,0.0004609828,0.00153361,0.0008446468,0.0006246,0.0005220305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007745144,"about_ca_system_score_gemma":0.001762361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001351015,"about_ca_topic_score_gemma":0.002183656,"domain_scores_codex":[0.9936404,0.001771947,0.0008789738,0.0006828026,0.002896408,0.0001294628],"domain_scores_gemma":[0.9909518,0.006421771,0.001298303,0.000205405,0.001085997,0.00003681549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001773894,0.00006839204,0.003187728,0.04590809,0.000525683,0.0002535793,0.0001546135,0.001473973,0.005502112,0.001184892,0.001305453,0.940258],"study_design_scores_gemma":[0.0002342428,0.005145297,0.09646722,0.04564996,0.01138438,0.01326974,0.00137607,0.00803484,0.1171565,0.0109033,0.6899538,0.0004246627],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003122718,0.9901432,0.005054704,0.0001569138,0.000128567,0.00006868947,0.0000573812,0.00002330332,0.001244481],"genre_scores_gemma":[0.04466254,0.9417902,0.01177221,0.0002140276,0.0002245913,0.0001389409,0.0001879095,0.00001526455,0.0009943785],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006375618,"threshold_uncertainty_score":0.03371787,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2034413448","doi":"10.1208/s12249-014-0134-7","title":"A Comparison of Granules Produced by High-Shear and Fluidized-Bed Granulation Methods","year":2014,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Granular flow and fluidized beds","field":"Engineering","cited_by":46,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Granulation; Granule (geology); Fluidized bed; Materials science; Shear (geology); Composite material; Chromatography; Chemical engineering; Chemistry; Engineering","authors":[{"name":"Garett Morin","is_ca":true},{"name":"Lauren Briens","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0140986046649488,"gpt":0.3110041433330002,"spread":0.2969055386680515,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001019335,0.0002577188,0.0004493021,0.0006011606,0.0002511952,0.0007169627,0.0002650614,0.0004389165,0.0006197914],"category_scores_gemma":[0.001072015,0.0001209491,0.0004996572,0.0005645975,0.0003300413,0.0006273139,0.0003185017,0.000352635,0.0001710174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002221999,"about_ca_system_score_gemma":0.0001818585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003050094,"about_ca_topic_score_gemma":0.0006030276,"domain_scores_codex":[0.9993655,0.0001215754,0.0000785306,0.00006594776,0.0003142857,0.00005421095],"domain_scores_gemma":[0.9994051,0.0002325717,0.0001155965,0.00006003831,0.000138188,0.00004851814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001675681,0.0001097438,0.001238341,0.000402231,0.0000297557,0.00008971478,0.0001125683,0.0004893018,0.9682054,0.0002168306,0.00006030637,0.02737008],"study_design_scores_gemma":[0.00009523453,0.001691833,0.01690339,0.00003103031,0.0001136537,0.0001884662,0.00008753542,0.002628443,0.9761727,0.00007403311,0.001991265,0.00002243585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843589,0.005298506,0.008318794,0.00007176019,0.00008045726,0.00006799803,0.0001569458,0.00007743869,0.001569259],"genre_scores_gemma":[0.9833342,0.002180839,0.01319602,0.00003395879,0.00002304433,0.00003793405,0.0002572938,0.00003092192,0.0009057706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001019335,"threshold_uncertainty_score":0.005390763,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2075633863","doi":"10.1208/pt0804103","title":"Characterization of tablet film coatings using a laser-induced breakdown spectroscopic technique","year":2007,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Laser-induced spectroscopy and plasma","field":"Engineering","cited_by":45,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"TransCanada (Canada); Merck Canada Inc. (Canada)","funders":"University of Connecticut","keywords":"Photodegradation; Coating; Materials science; Laser-induced breakdown spectroscopy; Ferric; Characterization (materials science); Film coating; Analytical Chemistry (journal); Laser; Chemical engineering; Chromatography; Composite material; Optics; Nanotechnology; Chemistry; Metallurgy; Photocatalysis; Organic chemistry","authors":[{"name":"M. Cecilia Madamba","is_ca":true},{"name":"Wayne M. Mullett","is_ca":true},{"name":"Smita Debnath","is_ca":true},{"name":"Elizabeth Kwong","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01384314734948728,"gpt":0.2538946724572221,"spread":0.2400515251077348,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001375284,0.0002359987,0.0002457,0.000294279,0.0003124582,0.0003983416,0.0002611313,0.0004242585,0.001564782],"category_scores_gemma":[0.0005177633,0.0001832072,0.0002206078,0.000274518,0.0001534655,0.0002945204,0.0001154102,0.0005096921,0.0002449361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002319459,"about_ca_system_score_gemma":0.0001660366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001851823,"about_ca_topic_score_gemma":0.002087784,"domain_scores_codex":[0.9998287,0.00001122853,0.00001045048,0.0000308336,0.00008941012,0.0000293579],"domain_scores_gemma":[0.9997504,0.00007488983,0.0000461426,0.00002289921,0.00008771614,0.00001791858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003307243,0.000007153886,0.0001283041,0.00002192037,0.000003188779,0.00002818851,0.00001450551,0.00004074601,0.9981743,0.00001284783,0.00002773977,0.001508025],"study_design_scores_gemma":[0.000005188554,0.0001237709,0.003308532,0.000002655311,0.000006717499,0.0001060495,0.00002370751,0.001066351,0.9947748,0.000009503079,0.0005694061,0.000003268831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886943,0.001322381,0.007196941,0.00007809356,0.00003300388,0.00005376836,0.0003584431,0.0000777885,0.002185287],"genre_scores_gemma":[0.9898654,0.0005890527,0.007252597,0.00003875251,0.000007951359,0.00002537122,0.0002648885,0.00003355888,0.001922491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001851823,"threshold_uncertainty_score":0.005234659,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1964272947","doi":"10.1208/s12249-014-0218-4","title":"Modified Cellulose Nanocrystal for Vitamin C Delivery","year":2014,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Advanced Cellulose Research Studies","field":"Materials Science","cited_by":45,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"CelluForce (Canada); University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; FPInnovations","keywords":"Chemistry; Antioxidant; Isothermal titration calorimetry; Titration; Nuclear chemistry; Chemical stability; Coacervate; Vitamin; Vitamin C; Chromatography; Organic chemistry; Biochemistry","authors":[{"name":"Seyedeh Parinaz Akhlaghi","is_ca":true},{"name":"Richard M. Berry","is_ca":true},{"name":"Kam Chiu Tam","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02503842622834928,"gpt":0.2924837623043704,"spread":0.2674453360760211,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001382368,0.0002083913,0.0001582282,0.0001502502,0.0001511049,0.0002464919,0.0001918823,0.000301079,0.001756552],"category_scores_gemma":[0.0001626917,0.00008872792,0.0002043068,0.0001180003,0.00008657705,0.0002076693,0.000112909,0.0003620557,0.0003855303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006763167,"about_ca_system_score_gemma":0.0003927025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004025125,"about_ca_topic_score_gemma":0.005909408,"domain_scores_codex":[0.9998996,0.000009060684,0.000006451192,0.00002694624,0.00003599532,0.00002186422],"domain_scores_gemma":[0.9999379,0.00001428584,0.00001320181,0.000006350074,0.00001597983,0.0000122845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006776215,0.00002050873,0.00004906131,0.00003976676,0.000006557529,0.00004862337,0.000008171606,0.0001457099,0.99496,0.0001968122,0.0001387074,0.004318404],"study_design_scores_gemma":[0.000006874963,0.00006226102,0.0001636219,0.000002311524,0.000007396899,0.00004545125,0.000003093093,0.0006810853,0.9972026,0.000009320277,0.00181286,0.000003157076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9588704,0.007327851,0.0193317,0.0002570116,0.0002302005,0.0001215332,0.000406844,0.0002359857,0.0132185],"genre_scores_gemma":[0.9772227,0.001654711,0.01301587,0.0001156528,0.00001615604,0.00004296805,0.0001698256,0.00003646491,0.007725536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004025125,"threshold_uncertainty_score":0.008003414,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2033386809","doi":"10.1208/s12249-012-9797-0","title":"Effect of Sampling Volume on Dry Powder Inhaler (DPI)-Emitted Aerosol Aerodynamic Particle Size Distributions (APSDs) Measured by the Next-Generation Pharmaceutical Impactor (NGI) and the Andersen Eight-Stage Cascade Impactor (ACI)","year":2012,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Aerosol; Dry-powder inhaler; Particle size; Dead space; Inhaler; Volume (thermodynamics); Aerodynamic diameter; Particle (ecology); Particle-size distribution; Cascade; Mechanics; Materials science; Environmental science; Analytical Chemistry (journal); Chemistry; Chromatography; Meteorology; Medicine; Thermodynamics; Anesthesia; Asthma; Physics; Internal medicine","authors":[{"name":"Hlack Mohammed","is_ca":false},{"name":"Daryl L. Roberts","is_ca":false},{"name":"Mark Copley","is_ca":false},{"name":"Mark Hammond","is_ca":false},{"name":"Steven C. Nichols","is_ca":false},{"name":"Jolyon P. Mitchell","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05800915737776779,"gpt":0.336852489667314,"spread":0.2788433322895462,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002109765,0.0006597976,0.000559744,0.0002531554,0.0003293888,0.001211923,0.0003477956,0.0005863495,0.001271276],"category_scores_gemma":[0.006113074,0.000595719,0.0005072419,0.0002683372,0.0006004715,0.0005302975,0.000355444,0.0004723094,0.0002751574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003153585,"about_ca_system_score_gemma":0.0006047503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002220759,"about_ca_topic_score_gemma":0.002382344,"domain_scores_codex":[0.9983062,0.0005652553,0.0001599664,0.0003296759,0.0004699934,0.0001689635],"domain_scores_gemma":[0.9943621,0.004355242,0.000300825,0.0003040021,0.000523637,0.0001541925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03013412,0.0007410592,0.02211639,0.0002797215,0.0002313953,0.0002067443,0.0004460653,0.002114868,0.9075351,0.0001412748,0.0004773404,0.03557596],"study_design_scores_gemma":[0.0002495176,0.008405549,0.06636968,0.00001928892,0.0002882664,0.0002186842,0.0001845528,0.006889773,0.9159601,0.00008615995,0.001285331,0.00004310013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908592,0.001223472,0.00612651,0.0001024209,0.0001764651,0.0001201981,0.0004538465,0.0002055921,0.0007323],"genre_scores_gemma":[0.9896119,0.0005059846,0.00800965,0.0002079646,0.00006373335,0.00009127561,0.0005364647,0.00009397608,0.0008791641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002220759,"threshold_uncertainty_score":0.01115763,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988233803","doi":"10.1208/s12249-014-0087-x","title":"Best Practices for the Development, Scale-up, and Post-approval Change Control of IR and MR Dosage Forms in the Current Quality-by-Design Paradigm","year":2014,"lang":"en","type":"review","venue":"AAPS PharmSciTech","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"Documentation; Quality (philosophy); Harmonization; Quality by Design; Good manufacturing practice; Scale (ratio); Best practice; Quality assurance; Control (management); Process (computing); Process management; Product (mathematics); Computer science; Dialog box; Engineering management; Pharmaceutical industry; New product development; Risk analysis (engineering); Manufacturing engineering; Business; Engineering; Operations management; Medicine; Pharmacology; Political science","authors":[{"name":"Glenn A. Van Buskirk","is_ca":false},{"name":"Satish Asotra","is_ca":false},{"name":"Christopher Balducci","is_ca":false},{"name":"Prabir K. Basu","is_ca":false},{"name":"Gerald C. DiDonato","is_ca":false},{"name":"Angelica Dorantes","is_ca":false},{"name":"W. Eickhoff","is_ca":false},{"name":"Tapash K. Ghosh","is_ca":false},{"name":"Mario Ángel-González","is_ca":false},{"name":"Theresa F. Henry","is_ca":false},{"name":"Matthew K. Howard","is_ca":false},{"name":"Jason Kamm","is_ca":false},{"name":"Steven Laurenz","is_ca":false},{"name":"Ryan J. MacKenzie","is_ca":false},{"name":"Patrick K. Noonan","is_ca":false},{"name":"Terrance Ocheltree","is_ca":false},{"name":"Umesh Pai","is_ca":false},{"name":"Richard Poska","is_ca":false},{"name":"Michael L. Putnam","is_ca":false},{"name":"Ramani R. Raghavan","is_ca":false},{"name":"Colleen Ruegger","is_ca":false},{"name":"Éric Sanchez","is_ca":false},{"name":"Vinod P. Shah","is_ca":false},{"name":"Zezhi Shao","is_ca":false},{"name":"Russell Somma","is_ca":false},{"name":"Vijay Tammara","is_ca":false},{"name":"Avinash G. Thombre","is_ca":false},{"name":"Bruce Thompson","is_ca":false},{"name":"Robert J. Timko","is_ca":false},{"name":"Satyam Upadrashta","is_ca":false},{"name":"Sivakumar Vaithiyalingam","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.4128121015561318,"gpt":0.5234909907803068,"spread":0.110678889224175,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0168271,0.001753911,0.001731418,0.003952164,0.0008473833,0.00363327,0.003347473,0.003332455,0.00352703],"category_scores_gemma":[0.007119521,0.0008965962,0.00143201,0.002727788,0.003715344,0.00451094,0.001760523,0.005247544,0.003756504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002432264,"about_ca_system_score_gemma":0.006315864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00220367,"about_ca_topic_score_gemma":0.0028483,"domain_scores_codex":[0.9895264,0.002369569,0.001409976,0.001059327,0.005363521,0.000271173],"domain_scores_gemma":[0.9931641,0.002911994,0.001021717,0.0006355149,0.002115563,0.000151053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004486994,0.000284245,0.0001839732,0.01292312,0.00005853605,0.0002818687,0.0004014185,0.001008847,0.00635666,0.04804866,0.01826938,0.9121383],"study_design_scores_gemma":[0.00003304967,0.0003336048,0.0006136678,0.007250008,0.00009861703,0.001488576,0.0002934675,0.0004286401,0.007797397,0.01497506,0.9666195,0.00006839352],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008163583,0.9381101,0.03614267,0.006761066,0.001349636,0.0003278422,0.00009276962,0.0001855815,0.01621389],"genre_scores_gemma":[0.009434199,0.9068063,0.07268057,0.003520354,0.0004517308,0.0003840807,0.0002118493,0.00005649188,0.006454471],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0168271,"threshold_uncertainty_score":0.08899122,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2040610001","doi":"10.1208/s12249-010-9538-1","title":"Monitoring Fluidized Bed Drying of Pharmaceutical Granules","year":2010,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Food Drying and Modeling","field":"Agricultural and Biological Sciences","cited_by":41,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fluidization; Fluidized bed; Materials science; Entrainment (biomusicology); Chromatography; Environmental science; Chemistry; Pulp and paper industry; Composite material; Analytical Chemistry (journal); Acoustics","authors":[{"name":"Lauren Briens","is_ca":true},{"name":"Megan Bojarra","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03738314577873011,"gpt":0.2884691299892524,"spread":0.2510859842105223,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000275465,0.0003555362,0.0004974287,0.0002326813,0.0002870325,0.0005077859,0.0003142962,0.0004814939,0.0008259164],"category_scores_gemma":[0.0006415329,0.0001423364,0.0002676974,0.0002113619,0.0002071267,0.0004635878,0.000210128,0.0004248599,0.000200526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004178554,"about_ca_system_score_gemma":0.0001414385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009537989,"about_ca_topic_score_gemma":0.0006704863,"domain_scores_codex":[0.9997737,0.00002643654,0.000009983781,0.00005099691,0.0001099573,0.00002883876],"domain_scores_gemma":[0.9997894,0.0001000926,0.00003263271,0.00001680948,0.00004793474,0.00001314962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0008887381,0.0001397597,0.002564204,0.0001021557,0.00001861216,0.0001251814,0.00008044584,0.004304201,0.9753417,0.0001052309,0.0001913151,0.0161384],"study_design_scores_gemma":[0.00003293004,0.000407141,0.008440905,0.000009099643,0.00001493589,0.0001090615,0.0000464086,0.05797945,0.932385,0.00007090571,0.0004905766,0.00001364396],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932172,0.0003065351,0.005467859,0.00002512551,0.00002131356,0.0000268683,0.0001134887,0.0001246515,0.0006969675],"genre_scores_gemma":[0.9965631,0.0001997359,0.00265214,0.00001340032,0.000005024564,0.00001231769,0.0001012519,0.00001663611,0.0004363762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009537989,"threshold_uncertainty_score":0.00303179,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2026674852","doi":"10.1208/s12249-012-9879-z","title":"Investigating Gabapentin Polymorphism Using Solid-State NMR Spectroscopy","year":2012,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Advanced NMR Techniques and Applications","field":"Chemistry","cited_by":38,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"U.S. Public Health Service; U.S. Food and Drug Administration; Hamilton Health Sciences Foundation; University of Kentucky","keywords":"Powder diffraction; Recrystallization (geology); Polymorphism (computer science); Ball mill; Gabapentin; Dehydration; Materials science; Crystallography; Spray drying; Chemistry; Nuclear chemistry; Analytical Chemistry (journal); Chromatography","authors":[{"name":"Kassibla Elodie Dempah","is_ca":false},{"name":"Dewey H. Barich","is_ca":false},{"name":"Aditya Mohan Kaushal","is_ca":false},{"name":"Zhixin Zong","is_ca":false},{"name":"Salil D. Desai","is_ca":false},{"name":"Raj Suryanarayanan","is_ca":false},{"name":"Lee E. Kirsch","is_ca":false},{"name":"Eric J. Munson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03770550170187359,"gpt":0.3476818232988766,"spread":0.309976321597003,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002507778,0.0002047955,0.0002495854,0.0002842463,0.0002275963,0.0003835041,0.0002324145,0.0004033254,0.001566728],"category_scores_gemma":[0.0006629204,0.0001328776,0.000158363,0.0003390837,0.0004248636,0.000277681,0.0001675759,0.0004516401,0.0002119738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001774889,"about_ca_system_score_gemma":0.0001922425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001033298,"about_ca_topic_score_gemma":0.001247462,"domain_scores_codex":[0.9998266,0.00004542557,0.00001334497,0.00004072904,0.00003850878,0.00003542862],"domain_scores_gemma":[0.9995509,0.0001869648,0.0001292084,0.00004020856,0.00005188326,0.00004097698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006410153,0.00004683294,0.002715234,0.00002948735,0.00003403739,0.0001346223,0.00006781246,0.0002216668,0.9918801,0.0001762248,0.00008793722,0.003964998],"study_design_scores_gemma":[0.00008856135,0.0007984159,0.01539701,0.00001181547,0.0001045261,0.0009599433,0.0001544882,0.0038689,0.9756162,0.000449185,0.002522272,0.00002884421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969007,0.0001914601,0.001766965,0.0001104534,0.00001254892,0.00001034342,0.0002519262,0.0000303967,0.0007252236],"genre_scores_gemma":[0.9968712,0.0002065354,0.001969941,0.00006211373,0.000008225158,0.00001585613,0.0001727176,0.00002508059,0.0006685043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001566728,"threshold_uncertainty_score":0.005241275,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2526014106","doi":"10.1208/s12249-016-0634-8","title":"Carboxymethyl Starch Excipients for Drug Chronodelivery","year":2016,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Proteins in Food Systems","field":"Agricultural and Biological Sciences","cited_by":37,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Drug; Chemistry; Starch; Chromatography; Pharmacology; Food science; Medicine","authors":[{"name":"Pompilia Ispas‐Szabo","is_ca":true},{"name":"Patrick De Koninck","is_ca":true},{"name":"Carmen Calinescu","is_ca":true},{"name":"Mircea Alexandru Mateescu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03058429373127697,"gpt":0.2484636979195414,"spread":0.2178794041882645,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003415794,0.0003780923,0.0002243783,0.0003654761,0.0001725474,0.0003869503,0.000179792,0.0004109623,0.003353028],"category_scores_gemma":[0.0003315251,0.0001312449,0.0002485842,0.0001748453,0.0001526171,0.0004564003,0.0002704598,0.0006487055,0.001138172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000254336,"about_ca_system_score_gemma":0.0002898294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004522488,"about_ca_topic_score_gemma":0.0006204188,"domain_scores_codex":[0.9998242,0.00002508211,0.00001939314,0.00003345326,0.0000715956,0.00002621968],"domain_scores_gemma":[0.999868,0.00002793843,0.0000472743,0.00001236274,0.00002756116,0.00001680699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002284147,0.00005394272,0.0001366386,0.0003082933,0.00001963695,0.0002269108,0.00003198891,0.000160794,0.9325483,0.001287016,0.001576295,0.06342165],"study_design_scores_gemma":[0.00003971509,0.0005085662,0.0007310057,0.00005409587,0.00002994463,0.0007639855,0.00001800767,0.0007508281,0.9552576,0.0001618521,0.04167086,0.00001342944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6922075,0.1215613,0.1115537,0.001917105,0.002045804,0.0009038092,0.0009478079,0.00178165,0.06708123],"genre_scores_gemma":[0.894286,0.02986857,0.03195012,0.0007587147,0.0002095271,0.0002473195,0.0005331535,0.0002509307,0.04189561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003353028,"threshold_uncertainty_score":0.011217,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2167537149","doi":"10.1208/s12249-009-9202-9","title":"The Abbreviated Impactor Measurement (AIM) Concept: Part 1—Influence of Particle Bounce and Re-Entrainment—Evaluation with a “Dry” Pressurized Metered Dose Inhaler (pMDI)-Based Formulation","year":2009,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Aerosol; Metered-dose inhaler; Inhaler; Particle (ecology); Particle size; Environmental science; Process engineering; Mechanics; Meteorology; Physics; Engineering; Medicine; Chemical engineering","authors":[{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Mark Nagel","is_ca":true},{"name":"V. Avvakoumova","is_ca":true},{"name":"H. MacKay","is_ca":true},{"name":"R. Ali","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04535938199584736,"gpt":0.3033877848075851,"spread":0.2580284028117377,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002949006,0.001023392,0.0007045211,0.0004907633,0.0004770672,0.0009410734,0.001499484,0.001032918,0.002911176],"category_scores_gemma":[0.001867069,0.0005081749,0.0008511973,0.000383022,0.0005642268,0.000990055,0.000847353,0.0009228174,0.0006419699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003978297,"about_ca_system_score_gemma":0.0008045876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007844061,"about_ca_topic_score_gemma":0.0006922246,"domain_scores_codex":[0.9975617,0.0004884324,0.0001559921,0.0003262906,0.001370332,0.00009722214],"domain_scores_gemma":[0.9992065,0.0002168343,0.0001258801,0.0001349014,0.0002520263,0.00006382235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004370427,0.0009724172,0.003563387,0.001301648,0.0001420356,0.00007855309,0.0002154206,0.001577478,0.866379,0.00124652,0.001289582,0.1188636],"study_design_scores_gemma":[0.0005106574,0.01349514,0.01952635,0.00005488954,0.0003016139,0.0004065954,0.00009227101,0.009741938,0.941024,0.0002190988,0.01453529,0.00009210248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7980403,0.008328969,0.17555,0.0006790577,0.0007917107,0.003677465,0.001441366,0.001756772,0.009734379],"genre_scores_gemma":[0.8780974,0.002595507,0.1085131,0.0005578437,0.0001791197,0.001269426,0.0009361922,0.0001714774,0.00768002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002949006,"threshold_uncertainty_score":0.01559597,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1984885145","doi":"10.1208/pt070111","title":"Quantitative measurement of indomethacin crystallinity in indomethacin-silica gel binary system using differential scanning calorimetry and X-ray powder diffractometry","year":2006,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Crystallography and molecular interactions","field":"Chemistry","cited_by":34,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Women's Health Research Institute","funders":"Pfizer","keywords":"Differential scanning calorimetry; Crystallinity; Powder diffraction; Materials science; Chromatography; Silica gel; Analytical Chemistry (journal); High-performance liquid chromatography; Binary system; Phase (matter); Chemistry; Crystallography; Binary number; Organic chemistry; Thermodynamics","authors":[{"name":"Xiaohong Pan","is_ca":true},{"name":"Thomas N. Julian","is_ca":false},{"name":"Larry L. Augsburger","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03042598185138304,"gpt":0.2882111559237286,"spread":0.2577851740723456,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004965807,0.0005180311,0.0005494711,0.0005699449,0.0005075671,0.0003435444,0.000407871,0.000361461,0.001928419],"category_scores_gemma":[0.0006971167,0.000240351,0.0002338628,0.0008623424,0.0004820011,0.0004070134,0.0002046471,0.0008288102,0.0003472127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005140035,"about_ca_system_score_gemma":0.0005262468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001539932,"about_ca_topic_score_gemma":0.002791945,"domain_scores_codex":[0.9994676,0.00009171286,0.0000468185,0.00008174525,0.0002329994,0.00007918526],"domain_scores_gemma":[0.9994581,0.0002245317,0.00007474423,0.00006250191,0.0001350449,0.00004514767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001704241,0.00002629441,0.0001444077,0.00002650841,0.000005750592,0.0000124472,0.00002322719,0.00007627431,0.9984011,0.0000502039,0.00002580977,0.001037584],"study_design_scores_gemma":[0.000007152564,0.00007001259,0.0008773975,0.000001650919,0.000006241594,0.00001372947,0.0000102346,0.0006940127,0.9980355,0.00001271192,0.0002683192,0.000003169509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754469,0.002198847,0.01677306,0.0001524256,0.0001003972,0.0001453604,0.001025369,0.0002417173,0.003915995],"genre_scores_gemma":[0.9738761,0.002010911,0.01789822,0.00005083556,0.00004703355,0.0002647022,0.001473282,0.0001020705,0.004276946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001928419,"threshold_uncertainty_score":0.00645119,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1992984293","doi":"10.1208/s12249-014-0135-6","title":"In Vitro Dissolution of Generic Immediate-Release Solid Oral Dosage Forms Containing BCS Class I Drugs: Comparative Assessment of Metronidazole, Zidovudine, and Amoxicillin Versus Relevant Comparator Pharmaceutical Products in South Africa and India","year":2014,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Pharmaceutical Quality and Counterfeiting","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Rhodes University","keywords":"Bioequivalence; Biopharmaceutics Classification System; Dissolution testing; Dissolution; Dosage form; Metronidazole; Pharmacology; Amoxicillin; Chemistry; Biopharmaceutics; Zidovudine; Immediate release; Drug; Pharmacokinetics; Medicine; Antibiotics; In vitro; Human immunodeficiency virus (HIV); Organic chemistry; Virology; Pharmacognosy; Biochemistry","authors":[{"name":"Nallagundla H. S. Reddy","is_ca":false},{"name":"Srinivas Patnala","is_ca":false},{"name":"Raimar Löbenberg","is_ca":true},{"name":"Isadore Kanfer","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08320226199680628,"gpt":0.3936810319124722,"spread":0.3104787699156659,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008655818,0.0004962384,0.0006656598,0.0004759993,0.0002557703,0.0005529317,0.0004423169,0.0004159727,0.001927894],"category_scores_gemma":[0.001885679,0.0003427026,0.0007994944,0.0008204995,0.0004721363,0.0005859989,0.0003080431,0.0006527381,0.0002956587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005477484,"about_ca_system_score_gemma":0.0005803243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00480506,"about_ca_topic_score_gemma":0.004596164,"domain_scores_codex":[0.9991611,0.0003625172,0.000100548,0.00009799587,0.0001950861,0.00008269191],"domain_scores_gemma":[0.9985641,0.0006210133,0.0004383952,0.0001144545,0.0001483401,0.0001137253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.1218374,0.004705966,0.01696614,0.002189568,0.0006611993,0.0008117845,0.001552453,0.002965693,0.7984172,0.0004939162,0.0005684984,0.0488303],"study_design_scores_gemma":[0.002607921,0.09073254,0.0909275,0.00009256248,0.001371605,0.00166913,0.001054341,0.006305394,0.8000402,0.0001164269,0.004951863,0.0001304974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960482,0.002252839,0.0003700781,0.00004952492,0.00002511623,0.0000491174,0.0003450797,0.00001030339,0.0008497056],"genre_scores_gemma":[0.9961795,0.001761702,0.0009188859,0.00001867454,0.00001653368,0.00001724558,0.0003050318,0.000009168953,0.0007733269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00480506,"threshold_uncertainty_score":0.009554207,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2115701609","doi":"10.1208/s12249-009-9312-4","title":"Improved Quality Control Metrics for Cascade Impaction Measurements of Orally Inhaled Drug Products (OIPs)","year":2009,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"AstraZeneca","keywords":"Metric (unit); Boundary (topology); Particle size; Cascade impactor; Particle (ecology); Range (aeronautics); Cascade; Critical quality attributes; Aerosol; Biological system; Chemistry; Mechanics; Mathematics; Chromatography; Physics; Aerospace engineering; Engineering; Mathematical analysis; Geology","authors":[{"name":"Terrence P. Tougas","is_ca":false},{"name":"David Christopher","is_ca":false},{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Helen Strickland","is_ca":false},{"name":"Bruce Wyka","is_ca":false},{"name":"Mike Van Oort","is_ca":false},{"name":"Svetlana Lyapustina","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06848191495371969,"gpt":0.3588641632235611,"spread":0.2903822482698414,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006368004,0.0007754018,0.0006542615,0.002963911,0.0004817512,0.001467399,0.0006275339,0.0007114045,0.0009706139],"category_scores_gemma":[0.01314993,0.0002147835,0.0005196101,0.002247175,0.0002175133,0.001079495,0.0007100293,0.0005535627,0.0002700743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001577632,"about_ca_system_score_gemma":0.001359386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008453753,"about_ca_topic_score_gemma":0.008224005,"domain_scores_codex":[0.9915351,0.001364955,0.0007133586,0.0006869331,0.00540575,0.0002939438],"domain_scores_gemma":[0.9849215,0.002152942,0.002540325,0.0007211087,0.009345876,0.0003182556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00183794,0.0007689612,0.4137753,0.0007256457,0.0002823473,0.0001646531,0.0003938087,0.02075964,0.1193154,0.001739959,0.007408906,0.4328274],"study_design_scores_gemma":[0.0001131936,0.003502498,0.4503948,0.0001516544,0.0003334991,0.0005058139,0.0002653924,0.2576171,0.2761016,0.0009015216,0.009951876,0.000161005],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7661586,0.004031831,0.2091343,0.0006188633,0.000313477,0.001025018,0.005353101,0.002874923,0.01048986],"genre_scores_gemma":[0.9293467,0.0003477357,0.066383,0.000124324,0.00004752028,0.0001980997,0.002570718,0.00006215724,0.0009197698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008453753,"threshold_uncertainty_score":0.03367758,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2092432465","doi":"10.1208/s12249-011-9615-0","title":"Dissolution Testing of Sublingual Tablets: A Novel In Vitro Method","year":2011,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":30,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Dissolution; Dissolution testing; Chromatography; Distilled water; Reproducibility; Chemistry; In vitro; Materials science; Biopharmaceutics Classification System; Biochemistry","authors":[{"name":"Ousama Rachid","is_ca":true},{"name":"Mutasem Rawas‐Qalaji","is_ca":false},{"name":"F. Estelle R. Simons","is_ca":true},{"name":"Keith J. Simons","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3134304465760461,"gpt":0.4533946183114378,"spread":0.1399641717353918,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001030307,0.001157958,0.0008100325,0.0009599379,0.0004840684,0.0005705824,0.0007539058,0.0008396227,0.002287948],"category_scores_gemma":[0.00130258,0.0006691356,0.0006755875,0.0005170957,0.0005185019,0.0008525959,0.0007519019,0.001064215,0.001546151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000210695,"about_ca_system_score_gemma":0.0006122065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001406185,"about_ca_topic_score_gemma":0.003719352,"domain_scores_codex":[0.9979773,0.0005486498,0.0002237428,0.0003215711,0.0008285677,0.0001001108],"domain_scores_gemma":[0.998689,0.0005529991,0.0001961531,0.0001565328,0.0003293485,0.0000759934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001721606,0.00008560362,0.0002984181,0.0002425284,0.00001692112,0.0001067511,0.00009357717,0.00004075219,0.9894661,0.00009620774,0.0001214336,0.00925949],"study_design_scores_gemma":[0.00004405654,0.001257907,0.003447077,0.00003040625,0.0001196795,0.0008498598,0.00009263469,0.001654042,0.9866454,0.0000587357,0.005765079,0.0000349866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5690284,0.02066354,0.3727976,0.001243392,0.0008151844,0.002730454,0.003049864,0.001373012,0.02829855],"genre_scores_gemma":[0.5966191,0.01728663,0.3526834,0.0005294628,0.0003130843,0.001557187,0.002687078,0.0003414751,0.02798265],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.002287948,"threshold_uncertainty_score":0.007653952,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2169550736","doi":"10.1208/s12249-010-9452-6","title":"Relative Precision of Inhaler Aerodynamic Particle Size Distribution (APSD) Metrics by Full Resolution and Abbreviated Andersen Cascade Impactors (ACIs): Part 1","year":2010,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Aerosol; Particle size; Inhaler; Particle (ecology); Cascade; Aerodynamics; Simulation; Mechanics; Materials science; Chemistry; Computer science; Chromatography; Physics; Engineering; Medicine; Meteorology; Chemical engineering","authors":[{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Mark Nagel","is_ca":true},{"name":"Cathy Doyle","is_ca":true},{"name":"Rubina Ali","is_ca":true},{"name":"Valentina Avvakoumova","is_ca":true},{"name":"J. David Christopher","is_ca":false},{"name":"Jorge Quiroz","is_ca":false},{"name":"Helen Strickland","is_ca":false},{"name":"Terrence P. Tougas","is_ca":false},{"name":"Svetlana Lyapustina","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01333143260900439,"gpt":0.2774737416579906,"spread":0.2641423090489862,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.007040502,0.0006999656,0.000742116,0.001314029,0.0005985581,0.001756066,0.0007503558,0.001021415,0.001463657],"category_scores_gemma":[0.01604034,0.000494856,0.000580506,0.001004854,0.0004167203,0.001510993,0.001327257,0.0005632438,0.0006109203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006945775,"about_ca_system_score_gemma":0.0008073208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004081597,"about_ca_topic_score_gemma":0.004635433,"domain_scores_codex":[0.9928974,0.0009922502,0.0006595782,0.001372825,0.003929328,0.0001485373],"domain_scores_gemma":[0.9914528,0.003360364,0.0009376645,0.001727083,0.0024223,0.00009966647],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.004807989,0.0001825118,0.2329898,0.001769347,0.0009803383,0.0002180375,0.0008566567,0.03015437,0.2431213,0.003257102,0.01054944,0.4711132],"study_design_scores_gemma":[0.000146506,0.002173678,0.4148967,0.0003090361,0.0007212423,0.001661335,0.0004528716,0.1411521,0.4139805,0.001871834,0.02224537,0.0003887124],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7112625,0.01739905,0.238089,0.0006250826,0.001009618,0.0006064104,0.00876443,0.004186285,0.01805767],"genre_scores_gemma":[0.9596913,0.001090343,0.03512052,0.0002323506,0.00009286692,0.00009293541,0.001770765,0.0002942651,0.001614576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9929595,"threshold_uncertainty_score":0.03723419,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2028289480","doi":"10.1208/s12249-011-9662-6","title":"Non-impactor-Based Methods for Sizing of Aerosols Emitted from Orally Inhaled and Nasal Drug Products (OINDPs)","year":2011,"lang":"en","type":"review","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Nasal spray; Sizing; Aerosol; Active ingredient; Process engineering; Biochemical engineering; Particle size; Medicine; Particle (ecology); Drug; Environmental science; Nanotechnology; Computer science; Risk analysis (engineering); Pharmacology; Materials science; Chemistry; Nasal administration; Chemical engineering; Engineering","authors":[{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Richard Bauer","is_ca":false},{"name":"Svetlana Lyapustina","is_ca":false},{"name":"Terrence P. Tougas","is_ca":false},{"name":"Volker Glaab","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1040977435963014,"gpt":0.4299678482216157,"spread":0.3258701046253143,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001299217,0.001250505,0.001258675,0.003040333,0.0003016686,0.0007914889,0.001254425,0.0008811577,0.00277612],"category_scores_gemma":[0.001347988,0.0004304647,0.000884135,0.001421539,0.0005408126,0.001224216,0.0006218126,0.0009759835,0.00219286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003938458,"about_ca_system_score_gemma":0.0006326257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008242429,"about_ca_topic_score_gemma":0.001855383,"domain_scores_codex":[0.9986371,0.0001547166,0.00008307947,0.0001675509,0.0009090434,0.00004848474],"domain_scores_gemma":[0.9990804,0.0004694303,0.0001495699,0.00004290275,0.0002361101,0.00002154979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009357062,0.0001455618,0.000841637,0.01541481,0.0001154634,0.000482021,0.000165006,0.0006889589,0.08769484,0.002477016,0.002923717,0.8889574],"study_design_scores_gemma":[0.00005392804,0.001471194,0.01435098,0.004140564,0.000429359,0.009283179,0.0004575616,0.003494133,0.2721518,0.003656754,0.6903262,0.000184354],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005975181,0.9531313,0.03192916,0.0002250709,0.000385684,0.0001965891,0.00008761767,0.00009391008,0.007975547],"genre_scores_gemma":[0.03050542,0.9086224,0.04776198,0.0003063388,0.000298666,0.0002303009,0.0002064754,0.00004244549,0.01202594],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003040333,"threshold_uncertainty_score":0.009287059,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2036845640","doi":"10.1208/s12249-007-9004-x","title":"Study of the RESS Process for Producing Beclomethasone-17,21-Dipropionate Particles Suitable for Pulmonary Delivery","year":2008,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; GlaxoSmithKline","keywords":"Particle size; Beclometasone dipropionate; Supercritical fluid; Nozzle; Particle (ecology); Materials science; Particle-size distribution; Inhalation; Nanoparticle; Delivery system; Chemical engineering; Chemistry; Nanotechnology; Biomedical engineering; Lung; Medicine; Thermodynamics; Physical chemistry; Organic chemistry; Respiratory disease; Anesthesia","authors":[{"name":"Paul A. Charpentier","is_ca":true},{"name":"Ming Jia","is_ca":true},{"name":"Rahima A. Lucky","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08311408746123915,"gpt":0.3380001052577039,"spread":0.2548860177964647,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002925522,0.000216723,0.0002247238,0.0001791313,0.0002473781,0.0002656038,0.0001532293,0.0002661711,0.001667892],"category_scores_gemma":[0.0003216796,0.0001184505,0.0004218656,0.0001355585,0.0001951169,0.0003324194,0.0001335948,0.0003304201,0.0005135038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002519327,"about_ca_system_score_gemma":0.0003102882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001472372,"about_ca_topic_score_gemma":0.00172818,"domain_scores_codex":[0.9998391,0.00001908725,0.000007933661,0.00002695939,0.00007706272,0.00002973082],"domain_scores_gemma":[0.9998999,0.00002959788,0.00002423958,0.000009346788,0.00002791409,0.000009083874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001235086,0.00005278652,0.0002345916,0.0001185054,0.000008860314,0.00009957649,0.00006552057,0.0004211628,0.9944754,0.0002139943,0.00006541506,0.004120694],"study_design_scores_gemma":[0.00001576144,0.0006816549,0.002452243,0.000007701477,0.00002172617,0.0001050017,0.00006841053,0.002053842,0.9924016,0.00003425666,0.002148861,0.000008894407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901958,0.001374825,0.004263139,0.00008082373,0.00004336716,0.00008548028,0.0001525364,0.00004024405,0.003763895],"genre_scores_gemma":[0.9908239,0.0009211536,0.00448173,0.00003504374,0.00002078082,0.00003336998,0.0001520435,0.00001656382,0.0035155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001667892,"threshold_uncertainty_score":0.00557965,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071280193","doi":"10.1208/s12249-014-0241-5","title":"Simulation of In Vitro Dissolution Behavior Using DDDPlus™","year":2014,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":28,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Princess Nourah Bint Abdulrahman University","keywords":"Dissolution; IVIVC; Solubility; Chemistry; Dissolution testing; Computer science; Chromatography","authors":[{"name":"May Almukainzi","is_ca":true},{"name":"Arthur Okumu","is_ca":true},{"name":"Hai Wei","is_ca":true},{"name":"Raimar Löbenberg","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1457460299338186,"gpt":0.4521753681292468,"spread":0.3064293381954282,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000166469,0.0004139687,0.0003625189,0.0002006463,0.0003397708,0.000419079,0.0005397751,0.0008117433,0.003259005],"category_scores_gemma":[0.0005843416,0.0002979167,0.0005162231,0.000215991,0.0002244699,0.0002795767,0.0002187099,0.0003663317,0.0003640309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005819541,"about_ca_system_score_gemma":0.0007774846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01275431,"about_ca_topic_score_gemma":0.004328755,"domain_scores_codex":[0.9999061,0.00001081223,0.00000684233,0.00001730194,0.00003602137,0.00002299772],"domain_scores_gemma":[0.9997236,0.0001615728,0.00003218202,0.00001683111,0.00005238183,0.00001332333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001297451,0.0000962651,0.00141221,0.0001107861,0.00002210692,0.0002154548,0.00009824151,0.965194,0.02662327,0.001226575,0.000320407,0.004551029],"study_design_scores_gemma":[0.00001702506,0.0000665734,0.0002882838,0.000005329584,0.000006555888,0.00002355594,0.00001521495,0.9865956,0.01226053,0.00008760127,0.0006262653,0.000007482662],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9365007,0.0002495459,0.04045804,0.0002725922,0.0000811295,0.0001387751,0.00119245,0.0004180753,0.02068859],"genre_scores_gemma":[0.9842762,0.000179884,0.010806,0.00003255631,0.000006222685,0.00008678091,0.0003627376,0.00003351815,0.004216048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01275431,"threshold_uncertainty_score":0.02536011,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2059871355","doi":"10.1208/pt0804090","title":"Product quality research institute evaluation of cascade impactor profiles of pharmaceutical aerosols, part 3: Final report on a statistical procedure for determining equivalence","year":2007,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"United States Pharmacopeia","keywords":"Cascade impactor; Equivalence (formal languages); Cascade; Chemistry; Process engineering; Biochemical engineering; Mathematics; Aerosol; Chromatography; Organic chemistry; Engineering","authors":[{"name":"David Christopher","is_ca":false},{"name":"Wallace P. Adams","is_ca":false},{"name":"Anthony Amann","is_ca":false},{"name":"Craig M. Bertha","is_ca":false},{"name":"Peter R. Byron","is_ca":false},{"name":"William H. Doub","is_ca":false},{"name":"Craig Dunbar","is_ca":false},{"name":"Walter W. Hauck","is_ca":false},{"name":"Svetlana Lyapustina","is_ca":false},{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Beth Morgan","is_ca":false},{"name":"Steve Nichols","is_ca":false},{"name":"Ziqing Pan","is_ca":false},{"name":"Gur Jai Pal Singh","is_ca":false},{"name":"Terrence P. Tougas","is_ca":false},{"name":"Yi Tsong","is_ca":false},{"name":"Ron Wolff","is_ca":false},{"name":"Bruce Wyka","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.4595807739014676,"gpt":0.562282606473012,"spread":0.1027018325715444,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04222883,0.0009790442,0.001145651,0.003379656,0.001654526,0.00110178,0.00204087,0.001063697,0.005180762],"category_scores_gemma":[0.0798099,0.0007190929,0.002056588,0.002966361,0.001114422,0.001348348,0.001531681,0.001618711,0.001034076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001768402,"about_ca_system_score_gemma":0.005044614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006964795,"about_ca_topic_score_gemma":0.006577482,"domain_scores_codex":[0.9479208,0.01815706,0.003478868,0.002638158,0.0269559,0.000849233],"domain_scores_gemma":[0.9400627,0.02942373,0.003917688,0.008526932,0.01724449,0.0008245727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02372177,0.005164257,0.1139509,0.001037186,0.001130783,0.0001666379,0.001390716,0.01936097,0.2326518,0.01050311,0.005439282,0.5854826],"study_design_scores_gemma":[0.001399809,0.02961591,0.2858057,0.0001209786,0.001123824,0.0003938668,0.0003608525,0.09556253,0.57086,0.003193527,0.01126941,0.0002937273],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3571621,0.0007842366,0.6158571,0.0002259995,0.0001246735,0.009652896,0.00452816,0.00135513,0.01030967],"genre_scores_gemma":[0.5580392,0.000395012,0.429701,0.000165296,0.00008039258,0.003828104,0.003994631,0.000318638,0.003477687],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.04222883,"threshold_uncertainty_score":0.2233301,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2050736304","doi":"10.1208/s12249-012-9771-x","title":"Immunomodulatory and Physical Effects of Phospholipid Composition in Vaccine Adjuvant Emulsions","year":2012,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Proteins in Food Systems","field":"Agricultural and Biological Sciences","cited_by":26,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Research & Development Corporation","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Bill and Melinda Gates Foundation","keywords":"Squalene; POPC; Phosphatidylcholine; Phosphocholine; Emulsion; Chemistry; Adjuvant; Phospholipid; Immunogenicity; Chromatography; Antigen; Biochemistry; Biology; Immunology","authors":[{"name":"Christopher B. Fox","is_ca":false},{"name":"Susan L. Baldwin","is_ca":false},{"name":"Malcolm S. Duthie","is_ca":false},{"name":"Steven G. Reed","is_ca":true},{"name":"Thomas S. Vedvick","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008421605944770984,"gpt":0.2287094533389533,"spread":0.2202878473941824,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002869632,0.0002370241,0.000122394,0.0002103122,0.0001081449,0.0002253845,0.0001253275,0.0001800539,0.001316127],"category_scores_gemma":[0.0004854998,0.0001189106,0.0001444198,0.0001045707,0.0001984847,0.0003285389,0.0001953913,0.000395392,0.0001752543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001259607,"about_ca_system_score_gemma":0.0001915277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000263604,"about_ca_topic_score_gemma":0.0002208522,"domain_scores_codex":[0.9998893,0.00002922965,0.000008296881,0.00001565297,0.00002195648,0.00003561299],"domain_scores_gemma":[0.9998335,0.00006401441,0.00003491963,0.000007505023,0.00002804983,0.00003209437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002117807,0.0001185789,0.0003091625,0.00004936562,0.000008475032,0.000041957,0.00002279222,0.0001924816,0.9925915,0.00007018504,0.00002870618,0.004448954],"study_design_scores_gemma":[0.00008126516,0.001502839,0.001229131,0.000009330804,0.00002934378,0.00005439695,0.00001944109,0.0006167687,0.9959837,0.00004394588,0.0004258532,0.000004044715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976965,0.001137313,0.0004781914,0.00003416679,0.00002081924,0.00001295945,0.00004029912,0.00000868767,0.0005711299],"genre_scores_gemma":[0.9982504,0.000612511,0.0004237426,0.00003165879,0.00001329938,0.000009823947,0.00004332099,0.000006988953,0.0006081864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001316127,"threshold_uncertainty_score":0.004402876,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2027842762","doi":"10.1208/s12249-009-9201-x","title":"The Abbreviated Impactor Measurement (AIM) Concept: Part II—Influence of Evaporation of a Volatile Component—Evaluation with a “Droplet-Producing” Pressurized Metered Dose Inhaler (pMDI)-Based Formulation Containing Ethanol as Cosolvent","year":2009,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Aerosol; Cascade impactor; Metered-dose inhaler; Propellant; Inhaler; Chemistry; Particle (ecology); Particle size; Mass fraction; Analytical Chemistry (journal); Materials science; Chromatography; Medicine; Asthma","authors":[{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Mark Nagel","is_ca":true},{"name":"V. Avvakoumova","is_ca":true},{"name":"H. MacKay","is_ca":true},{"name":"R. Ali","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0508678424140485,"gpt":0.3146902610776127,"spread":0.2638224186635642,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002171123,0.0009170544,0.0005610483,0.0004141122,0.0004326401,0.0008216336,0.001209404,0.0008827426,0.001794457],"category_scores_gemma":[0.001524049,0.0004530518,0.0007475751,0.0003060169,0.0004791374,0.0009366789,0.0007389316,0.000743129,0.0004300079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004177656,"about_ca_system_score_gemma":0.0007160604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000523358,"about_ca_topic_score_gemma":0.0004949874,"domain_scores_codex":[0.9982377,0.0003422665,0.0001090206,0.0002656935,0.0009711733,0.00007409646],"domain_scores_gemma":[0.9993679,0.0001946587,0.00008921392,0.0001080706,0.0001883214,0.00005186392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001465339,0.0002823746,0.001943074,0.0004130559,0.00004687368,0.0000457388,0.00008457444,0.0006133358,0.9540518,0.0005779609,0.0003310276,0.0401449],"study_design_scores_gemma":[0.0001245254,0.003932307,0.007625957,0.00001607658,0.00008924494,0.0002340789,0.00003807751,0.00512648,0.9786929,0.00008980544,0.003995272,0.00003524789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8197867,0.005644901,0.1642435,0.0004109294,0.0004919029,0.002410392,0.0008272076,0.0009967092,0.005187843],"genre_scores_gemma":[0.8927007,0.001886706,0.09915942,0.0003767298,0.000112447,0.0008043742,0.0005657189,0.0001066446,0.004287311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002171123,"threshold_uncertainty_score":0.01148218,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2007728975","doi":"10.1208/pt0801023","title":"Application of thermal effusivity as a process analytical technology tool for monitoring and control of the roller compaction process","year":2007,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Injection Molding Process and Properties","field":"Engineering","cited_by":25,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Thermal effusivity; Compaction; Process (computing); Process engineering; Process analytical technology; Thermal; Computer science; Materials science; Work in process; Engineering; Composite material; Thermodynamics; Physics","authors":[{"name":"Mohamed K. Ghorab","is_ca":true},{"name":"Ramarao Chatlapalli","is_ca":false},{"name":"Shamim Hasan","is_ca":false},{"name":"A. D. S. Nagi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00948062138999798,"gpt":0.2816223325364081,"spread":0.2721417111464101,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008347247,0.000384827,0.0002735307,0.0006305171,0.0003631416,0.000600032,0.0003398327,0.0005254228,0.0004703991],"category_scores_gemma":[0.001202037,0.0002906886,0.0002549094,0.0005209292,0.0005110723,0.0006106104,0.0003614372,0.0005666626,0.0001435732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003264451,"about_ca_system_score_gemma":0.0002921946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004875498,"about_ca_topic_score_gemma":0.0008641561,"domain_scores_codex":[0.9994007,0.0001281741,0.0000319282,0.0001329872,0.0002615583,0.00004461355],"domain_scores_gemma":[0.9992751,0.0003221816,0.0001354817,0.00007832605,0.0001655049,0.00002344049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001205241,0.00002794489,0.000958553,0.00003526748,0.000006868197,0.00004121637,0.00005857815,0.0002338619,0.9883317,0.0002230894,0.00002867603,0.009933729],"study_design_scores_gemma":[0.000002631944,0.00009070928,0.001651763,0.00000303917,0.000009462369,0.00008311165,0.00001208638,0.00265678,0.995076,0.00003023898,0.0003777698,0.000006374765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.871637,0.002448745,0.1211607,0.0001627491,0.0000878273,0.00009230478,0.0001347736,0.0002965294,0.003979377],"genre_scores_gemma":[0.9672705,0.0007357478,0.03031156,0.00005678891,0.00001977431,0.00003755681,0.00003999762,0.00002352122,0.001504635],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.0008347247,"threshold_uncertainty_score":0.004414439,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2981362302","doi":"10.1208/s12249-019-1508-7","title":"Dexamethasone Degradation in Aqueous Medium and Implications for Correction of In Vitro Release from Sustained Release Delivery Systems","year":2019,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Nexen (Canada)","funders":"","keywords":"Dexamethasone; Degradation (telecommunications); Chemistry; Drug; Chromatography; Drug delivery; Aqueous solution; In vitro; Liberation; Dosage form; Pharmacology; Active ingredient; Saline; Biochemistry; Medicine; Organic chemistry; Anesthesia; Internal medicine","authors":[{"name":"Brock Matter","is_ca":false},{"name":"Alireza Ghaffari","is_ca":true},{"name":"David W. A. Bourne","is_ca":false},{"name":"Yan Wang","is_ca":false},{"name":"Stephanie Choi","is_ca":false},{"name":"Uday B. Kompella","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04691072721315722,"gpt":0.3706812302169032,"spread":0.323770503003746,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009624514,0.0004690679,0.0003357977,0.0002192837,0.0003181909,0.001058129,0.0003247565,0.0006857328,0.0008302266],"category_scores_gemma":[0.001907583,0.0002001398,0.0003470338,0.0002465298,0.000651204,0.0006454521,0.0002414703,0.0006507625,0.0002893851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008835197,"about_ca_system_score_gemma":0.0005167781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003538495,"about_ca_topic_score_gemma":0.002360607,"domain_scores_codex":[0.9992272,0.0002302303,0.00008241425,0.0001095019,0.0002587303,0.00009194097],"domain_scores_gemma":[0.9990663,0.000420895,0.0002091233,0.00007573708,0.0001940073,0.00003400046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004959224,0.00002915107,0.0005647825,0.0001156381,0.000008256499,0.0001839535,0.00007484468,0.0004210768,0.9908014,0.0001614567,0.00006294283,0.00708063],"study_design_scores_gemma":[0.000004410945,0.0001153895,0.0006104384,0.000005819522,0.00001052184,0.0001140184,0.00003951742,0.000954351,0.9973812,0.00002882319,0.0007288878,0.000006720008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9383942,0.01500183,0.0412359,0.0008857945,0.0004178457,0.0001467186,0.0004136036,0.0002356999,0.003268454],"genre_scores_gemma":[0.986433,0.003251473,0.006893307,0.00006881265,0.00002807148,0.00002756079,0.0001084399,0.00005064257,0.003138639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003538495,"threshold_uncertainty_score":0.007035792,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2563063606","doi":"10.1208/s12249-016-0693-x","title":"Membrane-Loaded Doxorubicin Liposomes Based on Ion-Pairing Technology with High Drug Loading and pH-Responsive Property","year":2016,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":24,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Zeta potential; Liposome; Particle size; In vivo; Chemistry; Drug delivery; Chromatography; Membrane; Pharmacokinetics; Surface charge; Biophysics; Materials science; Chemical engineering; Nanoparticle; Nanotechnology; Organic chemistry; Pharmacology; Biochemistry","authors":[{"name":"Hang Xu","is_ca":false},{"name":"Lu Zhang","is_ca":false},{"name":"Lin Li","is_ca":false},{"name":"Yang Liu","is_ca":false},{"name":"Yanhui Chao","is_ca":false},{"name":"Xiaolin Liu","is_ca":false},{"name":"Xing Tang","is_ca":false},{"name":"Haibing He","is_ca":false},{"name":"Qiming Kan","is_ca":false},{"name":"Cuifang Cai","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009040435237252318,"gpt":0.2185235303886281,"spread":0.2094830951513758,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001396237,0.000326911,0.0002009459,0.0001667028,0.0001515661,0.0002172691,0.0001523784,0.0003098267,0.0009439934],"category_scores_gemma":[0.0001359347,0.0001458777,0.0001604243,0.0001096889,0.0001661336,0.0005056173,0.0003140883,0.0003030029,0.0005258675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002717657,"about_ca_system_score_gemma":0.0001801355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002610813,"about_ca_topic_score_gemma":0.0002988415,"domain_scores_codex":[0.9999387,0.000008403379,0.000006516731,0.00001949032,0.00001337368,0.00001345202],"domain_scores_gemma":[0.9999546,0.000007481099,0.00001286418,0.000004727522,0.000009575921,0.00001075491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004785645,0.000008451596,0.0000527902,0.00002883922,0.00000208854,0.00002327893,0.000009126485,0.00004194297,0.9982746,0.0001769748,0.00003717192,0.001296844],"study_design_scores_gemma":[0.00001033638,0.00005686255,0.0002620364,0.0000017781,0.000007662482,0.00007561531,0.000003677804,0.0006805067,0.9976113,0.00002594415,0.001259725,0.000004555288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721826,0.001388702,0.02237644,0.0002667778,0.00006436565,0.0001010801,0.00018647,0.0002667088,0.003166923],"genre_scores_gemma":[0.9863729,0.0006457188,0.009749556,0.00007170576,0.00001437563,0.0000514547,0.0001703672,0.00003884646,0.002885113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009439934,"threshold_uncertainty_score":0.003157973,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016983161","doi":"10.1208/pt060229","title":"Monitoring the fluidized bed granulation process based onS-statistic analysis of a pressure time series","year":2005,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Spectroscopy and Chemometric Analyses","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Technische Universiteit Delft","keywords":"Granulation; Granule (geology); Statistic; Fluidized bed; Fluidization; Mathematics; Chromatography; Chemistry; Biological system; Materials science; Statistics; Composite material; Organic chemistry","authors":[{"name":"Gareth Chaplin","is_ca":true},{"name":"Todd Pugsley","is_ca":true},{"name":"Conrad Winters","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01272848937830527,"gpt":0.3015199022131861,"spread":0.2887914128348808,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005049281,0.0002384887,0.0004502459,0.0007479766,0.0002531313,0.0005276625,0.0003584363,0.0004436088,0.0004196111],"category_scores_gemma":[0.001342109,0.000130743,0.0002311348,0.000857975,0.0003173466,0.0004956474,0.0001739485,0.0004020908,0.0001112949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002538999,"about_ca_system_score_gemma":0.0002773296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009067982,"about_ca_topic_score_gemma":0.0007891332,"domain_scores_codex":[0.9995796,0.00006015552,0.00001998225,0.00006427064,0.0002465045,0.00002936987],"domain_scores_gemma":[0.9991654,0.0004511313,0.0001430567,0.00004586437,0.0001576925,0.00003684993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0009347575,0.000238547,0.01891301,0.0001231523,0.00005270986,0.0001904938,0.0001886544,0.01073213,0.8891251,0.0007115265,0.0003296859,0.07846028],"study_design_scores_gemma":[0.00002166196,0.0007127829,0.07205008,0.000007042476,0.0000495053,0.0003946393,0.00008028556,0.4194793,0.5057679,0.0005499333,0.0008347825,0.00005211185],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9337887,0.0001638168,0.06441049,0.00007620741,0.00002241612,0.00002724501,0.0001818042,0.0005197509,0.0008096409],"genre_scores_gemma":[0.9867811,0.00007144771,0.01272745,0.00001458495,0.00001283065,0.0000115885,0.000123448,0.00001839467,0.0002392305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009067982,"threshold_uncertainty_score":0.002670348,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2052951306","doi":"10.1208/s12249-011-9703-1","title":"The Effect of the Chopper on Granules from Wet High-Shear Granulation Using a PMA-1 Granulator","year":2011,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Granular flow and fluidized beds","field":"Engineering","cited_by":23,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Impeller; Chopper; Agitator; Materials science; Granule (geology); Granulation; Composite material; Mechanics; Engineering; Physics; Electrical engineering","authors":[{"name":"Lauren Briens","is_ca":true},{"name":"Ryan Logan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01255753293829391,"gpt":0.205580813640299,"spread":0.1930232807020051,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004359806,0.0003283848,0.0004418254,0.000195349,0.0002889842,0.0003762121,0.0002675991,0.0004324701,0.001484254],"category_scores_gemma":[0.0005885771,0.0002088311,0.000357156,0.000216744,0.0004188234,0.0004610502,0.0002581912,0.0004465437,0.0002189728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001821251,"about_ca_system_score_gemma":0.000193933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000605378,"about_ca_topic_score_gemma":0.0009350245,"domain_scores_codex":[0.9997278,0.00005670677,0.00003000255,0.00004727849,0.00006688569,0.00007130532],"domain_scores_gemma":[0.9994301,0.0002648656,0.0001275419,0.00005121968,0.00005743689,0.00006877024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001682348,0.00006840227,0.0003551124,0.0001068043,0.00001183816,0.00008381021,0.00005629355,0.0001978974,0.9945073,0.00002218339,0.00003638767,0.002871655],"study_design_scores_gemma":[0.00001981866,0.0006592578,0.004501501,0.000005053617,0.00002022226,0.00003559377,0.00002200713,0.0005494564,0.9939622,0.000007400392,0.0002131683,0.00000426617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984667,0.0005702994,0.0004695783,0.00003245605,0.00001674516,0.00001111437,0.00005152764,0.0000228908,0.0003585703],"genre_scores_gemma":[0.9984021,0.0002331342,0.0008986598,0.00003896494,0.00001076613,0.000005053923,0.0000604961,0.00001730347,0.0003335581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001484254,"threshold_uncertainty_score":0.004965305,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1997662619","doi":"10.1208/s12249-012-9905-1","title":"Good Cascade Impactor Practice (GCIP) and Considerations for “In-Use” Specifications","year":2013,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Particle size; Cascade; Nozzle; Pressure drop; Calibration; Process engineering; Traceability; Aerodynamics; Mechanics; Statistics; Computer science; Mechanical engineering; Environmental science; Chemistry; Mathematics; Engineering; Physics; Chromatography","authors":[{"name":"Steve Nichols","is_ca":false},{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Christopher Shelton","is_ca":false},{"name":"Daryl L. Roberts","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09108240692460044,"gpt":0.3371765378743612,"spread":0.2460941309497607,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.08423135,0.001534985,0.0008139407,0.002855483,0.007646406,0.009958867,0.00836599,0.01046009,0.03394202],"category_scores_gemma":[0.1737601,0.00203562,0.001448986,0.001170616,0.005968442,0.01238088,0.005577442,0.006093754,0.01348162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006592785,"about_ca_system_score_gemma":0.0308075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01203069,"about_ca_topic_score_gemma":0.02384648,"domain_scores_codex":[0.8912556,0.02699604,0.009204866,0.004187825,0.06188108,0.006474734],"domain_scores_gemma":[0.8137798,0.05956413,0.008627669,0.02373786,0.08567228,0.008618291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000885811,0.002217014,0.03115554,0.002427515,0.0001272617,0.004037031,0.008753117,0.01535028,0.03451255,0.2154808,0.2958288,0.3892243],"study_design_scores_gemma":[0.0003502059,0.003195841,0.02575568,0.004475143,0.000149594,0.005681603,0.009718116,0.01331039,0.04563623,0.0762243,0.8148704,0.0006325753],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"methods","genre_scores_codex":[0.05525437,0.00345518,0.2123032,0.09996299,0.002560779,0.006403153,0.0006952775,0.008909822,0.6104551],"genre_scores_gemma":[0.5226352,0.002083872,0.3207943,0.03792432,0.001072897,0.003366061,0.001109721,0.003248416,0.1077652],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.08423135,"threshold_uncertainty_score":0.4454632,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2083992411","doi":"10.1208/s12249-015-0306-0","title":"Sublingual Diffusion of Epinephrine Microcrystals from Rapidly Disintegrating Tablets for the Potential First-Aid Treatment of Anaphylaxis: In Vitro and Ex Vivo Study","year":2015,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"Nova Southeastern University","keywords":"Ex vivo; In vivo; Particle size; Differential scanning calorimetry; Pharmacology; Sublingual administration; Chemistry; Materials science; Chromatography; In vitro; Medicine; Biochemistry","authors":[{"name":"Mutasem Rawas‐Qalaji","is_ca":false},{"name":"Shima Werdy","is_ca":false},{"name":"Ousama Rachid","is_ca":true},{"name":"F. Estelle R. Simons","is_ca":true},{"name":"Keith J. Simons","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03620472078288892,"gpt":0.3215639256871664,"spread":0.2853592049042774,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002103501,0.0002072201,0.0002988623,0.0001036239,0.000125648,0.0002359711,0.0001585592,0.0002068662,0.0008040679],"category_scores_gemma":[0.0002782824,0.00014298,0.0002456061,0.00009876714,0.000172441,0.0002962535,0.0001042412,0.0003806686,0.0001555676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001529972,"about_ca_system_score_gemma":0.000149787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008213135,"about_ca_topic_score_gemma":0.001259899,"domain_scores_codex":[0.999872,0.00003196825,0.000006067384,0.00002500216,0.00003938564,0.00002557667],"domain_scores_gemma":[0.9998444,0.00007780359,0.00003211251,0.00001145529,0.00001818447,0.00001594984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005284078,0.0001433124,0.0001491546,0.0001102669,0.00001212187,0.0001427088,0.00006732251,0.0002876675,0.9935088,0.00007467111,0.0001294206,0.004846104],"study_design_scores_gemma":[0.00009526485,0.002094961,0.003119697,0.000007759465,0.00005222812,0.0002897554,0.00004579715,0.002807597,0.9903373,0.00001564701,0.001123613,0.00001049029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940298,0.002787409,0.00193563,0.00006864055,0.00003829578,0.00003898375,0.00009930175,0.00001839875,0.0009836642],"genre_scores_gemma":[0.9953673,0.001652069,0.0017502,0.00003204367,0.00002419573,0.000017312,0.00007413543,0.000009978986,0.001072751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008213135,"threshold_uncertainty_score":0.002689898,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1975372021","doi":"10.1208/pt040224","title":"Evaluation of the conformity index and the mahalanobis distance as a tool for process analysis: A technical note","year":2003,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Spectroscopy and Chemometric Analyses","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Purdue Pharma (Canada)","funders":"Purdue Pharma; Purdue University","keywords":"Mahalanobis distance; Conformity; Index (typography); Process (computing); Conformity assessment; Computer science; Process engineering; Data mining; Statistics; Mathematics; Engineering; Psychology; Artificial intelligence; Operations management; World Wide Web; Social psychology","authors":[{"name":"Gary E. Ritchie","is_ca":true},{"name":"Howard Mark","is_ca":false},{"name":"Emil W. Ciurczak","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01820109273631799,"gpt":0.3447071638900421,"spread":0.3265060711537241,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006591592,0.001146402,0.001420768,0.003227131,0.000557546,0.001817106,0.001742474,0.001075479,0.002261777],"category_scores_gemma":[0.02294641,0.0005215445,0.001300577,0.002708596,0.0007850672,0.00237863,0.001134914,0.001565015,0.001596981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006229571,"about_ca_system_score_gemma":0.0009293942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001470171,"about_ca_topic_score_gemma":0.001455193,"domain_scores_codex":[0.992434,0.002073767,0.0005121563,0.0006212005,0.004234142,0.0001247147],"domain_scores_gemma":[0.9823813,0.01027536,0.0007354565,0.001840402,0.004595024,0.0001724958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000425077,0.0003234452,0.007660155,0.0003655374,0.0002391106,0.0001698322,0.0001812285,0.04516568,0.09899326,0.01996811,0.002184705,0.8243238],"study_design_scores_gemma":[0.00002474277,0.0006144707,0.005489509,0.00002982682,0.0001033022,0.0005534122,0.0001103575,0.7967485,0.1793217,0.01110236,0.005775657,0.0001262541],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.02249815,0.0004549523,0.9743341,0.0001156482,0.0000482685,0.00006352446,0.0001536686,0.001012473,0.001319236],"genre_scores_gemma":[0.1895169,0.0004507701,0.8063926,0.00003562729,0.00005753427,0.0001597978,0.0005007393,0.0004422872,0.002443825],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.006591592,"threshold_uncertainty_score":0.03486007,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2042749236","doi":"10.1208/s12249-010-9437-5","title":"Influence of Drying Procedure and of Low Degree of Substitution on the Structural and Drug Release Properties of Carboxymethyl Starch","year":2010,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Food composition and properties","field":"Nursing","cited_by":20,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Excipient; Chemistry; Starch; Solvent; Freeze-drying; Spray drying; Chromatography; Chemical engineering; Materials science; Nuclear chemistry; Organic chemistry","authors":[{"name":"Marc Lemieux","is_ca":true},{"name":"Patrick Gosselin","is_ca":false},{"name":"Mircea Alexandru Mateescu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02313907786059777,"gpt":0.2521274445211993,"spread":0.2289883666606016,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002949529,0.0003155154,0.0001905488,0.000225617,0.0001449428,0.0002736262,0.0001278969,0.0002138535,0.001085142],"category_scores_gemma":[0.0007037461,0.0001837492,0.0002617462,0.0002469563,0.000303178,0.0003613681,0.0001232484,0.0003790267,0.0001774102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001120096,"about_ca_system_score_gemma":0.0002017522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005046158,"about_ca_topic_score_gemma":0.0007326287,"domain_scores_codex":[0.9998488,0.00003176093,0.0000238605,0.00003290749,0.00003550758,0.00002710202],"domain_scores_gemma":[0.9994282,0.0002521908,0.0001448107,0.00004572945,0.00006358878,0.00006549722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000703362,0.00004792656,0.0005616967,0.00006778027,0.00001652946,0.00008500659,0.00006152823,0.0002072105,0.9955981,0.00005389,0.00002299664,0.002574055],"study_design_scores_gemma":[0.0000212609,0.0005797937,0.005071993,0.000008543761,0.00004558239,0.000112931,0.00003344395,0.0005923198,0.9930792,0.00001827617,0.0004232983,0.00001316412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981709,0.0008647139,0.0004580555,0.00001893728,0.00002265705,0.0000047729,0.00004004865,0.00001028581,0.0004097219],"genre_scores_gemma":[0.9982476,0.000577676,0.0006156826,0.00002479411,0.00001294104,0.000004393168,0.00007097764,0.00001962549,0.0004262722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085142,"threshold_uncertainty_score":0.003630102,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2581028920","doi":"10.1208/s12249-017-0721-5","title":"Enterolactone glucuronide and β-glucuronidase in antibody directed enzyme prodrug therapy for targeted prostate cancer cell treatment","year":2017,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Phytoestrogen effects and research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Saskatchewan Health Research Foundation","keywords":"Chemistry; Prodrug; In vivo; Prostate cancer; Antibody; Pharmacology; Biochemistry; Enzyme; Cancer; Immunology; Internal medicine; Biology; Medicine","authors":[{"name":"Yunyun Di","is_ca":true},{"name":"Shaoping Ji","is_ca":true},{"name":"Philipp Wolf","is_ca":false},{"name":"Ed S. Krol","is_ca":true},{"name":"Jane Alcorn","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02642777053970425,"gpt":0.3812399689674331,"spread":0.3548121984277288,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001412799,0.0002216887,0.0001414747,0.0002242132,0.00007449667,0.0002351587,0.0001498957,0.0002608198,0.0009837066],"category_scores_gemma":[0.00004809333,0.0001081246,0.0001336203,0.000140665,0.0001235681,0.0001972072,0.0001415966,0.0003858955,0.0002811101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002845687,"about_ca_system_score_gemma":0.0002253465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007529599,"about_ca_topic_score_gemma":0.001903072,"domain_scores_codex":[0.9999605,0.000008842676,0.000002103471,0.00000560794,0.00001146011,0.00001139673],"domain_scores_gemma":[0.9999876,0.000002270031,0.000002998816,0.000001344741,0.000001944744,0.000003850685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009388078,0.0002539991,0.0004005035,0.00008729721,0.00002095992,0.0002255146,0.00002244147,0.001012909,0.9437695,0.001112249,0.0003683157,0.05178752],"study_design_scores_gemma":[0.0002001981,0.0022949,0.001598764,0.00001344406,0.00006827147,0.0007169563,0.00002193031,0.001894152,0.9774031,0.0001899693,0.01559055,0.000007863571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9564742,0.02334282,0.009953799,0.0004822318,0.0001087291,0.0001002186,0.000191215,0.0001386836,0.009208047],"genre_scores_gemma":[0.9822736,0.00737389,0.002935114,0.00009027027,0.00001352484,0.00002729777,0.0001359031,0.00001552947,0.007134754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009837066,"threshold_uncertainty_score":0.003290832,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2914231058","doi":"10.1208/s12249-018-1286-7","title":"Methods to Assess Mixing of Pharmaceutical Powders","year":2019,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Spectroscopy and Chemometric Analyses","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Process engineering; Process analytical technology; Pharmaceutical manufacturing; Computer science; Quality by Design; Process (computing); Biochemical engineering; Quality (philosophy); New product development; Manufacturing engineering; Work in process; Engineering; Operations management; Business","authors":[{"name":"Allison Crouter","is_ca":true},{"name":"Lauren Briens","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07468100929846573,"gpt":0.4454709133964354,"spread":0.3707899040979696,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002574514,0.001138994,0.0005313845,0.002937131,0.0007852449,0.0009144037,0.001193392,0.001327548,0.003045539],"category_scores_gemma":[0.003636859,0.0005932191,0.000582895,0.00121642,0.0004994093,0.0008541319,0.0009670325,0.001910549,0.001970538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006107099,"about_ca_system_score_gemma":0.0007649806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007076666,"about_ca_topic_score_gemma":0.00150795,"domain_scores_codex":[0.9940634,0.0005128937,0.0002460363,0.0009760545,0.004042244,0.0001594186],"domain_scores_gemma":[0.9982705,0.0003786462,0.0003891783,0.0002238397,0.0006670433,0.00007082335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001668563,0.0001617267,0.002222634,0.0003671157,0.00007261508,0.00004440877,0.0001215299,0.0004011574,0.9301546,0.001033628,0.0008369698,0.06441678],"study_design_scores_gemma":[0.0000211631,0.000349283,0.004467436,0.00003573845,0.0000789358,0.0002860929,0.00005444553,0.01043884,0.9746697,0.0005002928,0.009064145,0.00003392314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.09858345,0.007088637,0.874866,0.0003366332,0.0004868305,0.001610624,0.001304521,0.002606742,0.01311655],"genre_scores_gemma":[0.3231082,0.004521652,0.6544973,0.0007285737,0.0001529283,0.002135266,0.001710559,0.0004406446,0.01270497],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003045539,"threshold_uncertainty_score":0.01361549,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1968402896","doi":"10.1208/s12249-010-9473-1","title":"Relative Precision of Inhaler Aerodynamic Particle Size Distribution (APSD) Metrics by Full Resolution and Abbreviated Andersen Cascade Impactors (ACIs): Part 2—Investigation of Bias in Extra-Fine Mass Fraction with AIM-HRT Impactor","year":2010,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Cascade impactor; Particle (ecology); Coating; Particle size; Materials science; Particle-size distribution; Calibration; Chemistry; Analytical Chemistry (journal); Composite material; Chromatography; Mathematics; Geology; Statistics","authors":[{"name":"Jolyon P. Mitchell","is_ca":true},{"name":"Mark Nagel","is_ca":true},{"name":"Cathy Doyle","is_ca":true},{"name":"Rubina Ali","is_ca":true},{"name":"Valentina Avvakoumova","is_ca":true},{"name":"J. David Christopher","is_ca":false},{"name":"Jorge Quiroz","is_ca":false},{"name":"Helen Strickland","is_ca":false},{"name":"Terrence P. Tougas","is_ca":false},{"name":"Svetlana Lyapustina","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02551183319408672,"gpt":0.2816151227938798,"spread":0.2561032895997931,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008712402,0.0005409118,0.0005957678,0.0009048234,0.00055958,0.001197288,0.0008910584,0.0009990247,0.001062382],"category_scores_gemma":[0.01856285,0.0004923562,0.0005343202,0.00075955,0.0004253304,0.001245009,0.0010342,0.0005028268,0.0004649371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006252886,"about_ca_system_score_gemma":0.0006506252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004291673,"about_ca_topic_score_gemma":0.004790355,"domain_scores_codex":[0.9919401,0.001479885,0.0006914281,0.001858077,0.003882613,0.0001480142],"domain_scores_gemma":[0.9884883,0.005166912,0.001192943,0.002442268,0.002581249,0.000128387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008597697,0.0002477502,0.4623552,0.001245406,0.001823568,0.0002162975,0.001273792,0.01790796,0.2487499,0.002070479,0.005000551,0.2505113],"study_design_scores_gemma":[0.0002142468,0.002544027,0.5565529,0.000156008,0.0008628233,0.001351184,0.0003482391,0.08764052,0.3399433,0.001036022,0.009109921,0.0002408371],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8640516,0.006119253,0.1158858,0.0002892804,0.000465508,0.0003480517,0.004319534,0.001793117,0.006727867],"genre_scores_gemma":[0.9770688,0.0004024349,0.02001777,0.0002359579,0.00005360322,0.00006569101,0.001009579,0.0002280742,0.0009180256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008712402,"threshold_uncertainty_score":0.04607612,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}