{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":40,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":40,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"785d6a52a78a","filters":{"venue":"Anti-Cancer Agents in Medicinal Chemistry"}},"results":[{"id":"W3004925426","doi":"10.2174/1871520620666200203125712","title":"CDK1 in Breast Cancer: Implications for Theranostic Potential","year":2020,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Breast cancer; Cancer; Cyclin-dependent kinase; Medicine; Cyclin-dependent kinase 1; Cancer research; Palbociclib; CDK inhibitor; Tumor microenvironment; Oncology; Internal medicine; Metastatic breast cancer; Cell cycle","authors":[{"name":"Sepideh Izadi","is_ca":false},{"name":"Afshin Nikkhoo","is_ca":false},{"name":"Mohammad Hojjat‐Farsangi","is_ca":false},{"name":"Afshin Namdar","is_ca":true},{"name":"Gholamreza Azizi","is_ca":false},{"name":"Hamed Mohammadi","is_ca":false},{"name":"Mehdi Yousefi","is_ca":false},{"name":"Farhad Jadidi‐Niaragh","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05128603590659644,"gpt":0.3866158316362135,"spread":0.3353297957296171,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002038477,0.000693973,0.002421027,0.0001793824,0.00006623456,0.00002003435,0.0005009332,0.0006886462,0.0008128741],"category_scores_gemma":[0.0001080062,0.0006355128,0.0005761307,0.0009088588,0.0001730836,0.00004486648,0.0001098065,0.001359,0.00001466157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001406527,"about_ca_system_score_gemma":0.002352111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003317474,"about_ca_topic_score_gemma":0.00002819169,"domain_scores_codex":[0.9965821,0.00005345435,0.00114433,0.001078524,0.0004454895,0.0006961279],"domain_scores_gemma":[0.9983409,0.00008511265,0.0004577243,0.0006501321,0.0001304449,0.0003356979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000192198,0.0003041372,0.0008185596,0.04437278,0.0006916644,0.0003577786,0.0001258015,0.00003855445,0.002810415,0.000004264702,0.007372235,0.9429116],"study_design_scores_gemma":[0.005324468,0.00006873142,0.001962103,0.05781513,0.003581457,0.0007571454,0.0000584836,0.0001425692,0.0004596504,0.00002598561,0.9288721,0.0009321434],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005784304,0.9922858,0.0001539275,0.002431142,0.0005489047,0.002111349,0.001366035,0.00006463903,0.0004597334],"genre_scores_gemma":[0.003902735,0.9908149,0.00006250592,0.0006418459,0.001456766,0.001985513,0.0006720967,0.0001713534,0.0002923321],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9419795,"threshold_uncertainty_score":0.9996096,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2166014214","doi":"10.2174/187152006778699121","title":"Pharmacokinetics and Pharmacodynamics of Lipidic Nano-Particles in Cancer","year":2006,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":142,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Pharmacodynamics; Pharmacokinetics; Cancer; Nano-; Pharmacology; Medicine; Internal medicine; Materials science; Composite material","authors":[{"name":"Theresa M. Allen","is_ca":true},{"name":"Wilson Cheng","is_ca":false},{"name":"Jennifer I. Hare","is_ca":false},{"name":"Kimberley M. Laginha","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07840378712469968,"gpt":0.4403396305646383,"spread":0.3619358434399386,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005668637,0.0004126808,0.001240834,0.000182912,0.00002718322,0.00003042654,0.0009358343,0.0001742136,0.00005651004],"category_scores_gemma":[0.00004381373,0.0003875135,0.0001339319,0.0009652755,0.00018276,0.0001529852,0.0003778813,0.0005505129,0.000001133305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002987299,"about_ca_system_score_gemma":0.0006196981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003094512,"about_ca_topic_score_gemma":0.00001676974,"domain_scores_codex":[0.9971896,0.0001740673,0.0009874419,0.0006779153,0.0005680323,0.0004029561],"domain_scores_gemma":[0.9987377,0.0002768066,0.0004918315,0.0003233164,0.00006341109,0.0001069339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000526845,0.0001773001,0.001287006,0.01804462,0.0000840586,0.00006251282,0.0001194875,0.003558413,0.0005577898,0.0000240862,0.0004523019,0.9756272],"study_design_scores_gemma":[0.006500328,0.00007711407,0.00367545,0.07433953,0.001491395,0.0001573592,0.0000604738,0.2388304,0.02044384,0.0008378136,0.6503861,0.003200198],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02307303,0.9745318,0.001246,0.00007146258,0.0004871342,0.0003007256,0.00006578713,0.00002234581,0.0002017558],"genre_scores_gemma":[0.004928143,0.9931222,0.001338236,0.00008528892,0.000268527,0.0001096395,0.00002340969,0.00003040692,0.00009410501],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.972427,"threshold_uncertainty_score":0.9998577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2170500301","doi":"10.2174/187152012802649978","title":"Targeting Tumor Ubiquitin-Proteasome Pathway with Polyphenols for Chemosensitization","year":2012,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Flavonoids in Medical Research","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Cancer Institute","keywords":"Chemosensitizer; Pharmacology; Bortezomib; Curcumin; Proteasome; Apigenin; Proteasome inhibitor; Luteolin; Biology; Polyphenol; Resveratrol; Biochemistry; Quercetin; Chemistry; Multiple drug resistance; Drug resistance; Flavonoid; Antioxidant; Microbiology; Immunology","authors":[{"name":"Min Shen","is_ca":false},{"name":"Tak Hang Chan","is_ca":true},{"name":"Q. Ping Dou","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1032670195889138,"gpt":0.4147369078957164,"spread":0.3114698883068026,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001542318,0.0008430954,0.0028014,0.000192578,0.0001320242,0.00003272606,0.0005183967,0.000642085,0.001405748],"category_scores_gemma":[0.001529487,0.00062582,0.0003360983,0.0007803102,0.00045472,0.0001038219,0.0001811331,0.001976981,0.00003661637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009298445,"about_ca_system_score_gemma":0.002014693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000414202,"about_ca_topic_score_gemma":0.000001313061,"domain_scores_codex":[0.9944916,0.0001112274,0.001245066,0.00104893,0.001675222,0.001427936],"domain_scores_gemma":[0.997251,0.0003642239,0.0006218938,0.0007180554,0.0003249945,0.0007198061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002551178,0.0004443451,0.0004488363,0.1905075,0.0005421274,0.0005806431,0.0001804379,0.000002952719,0.004493928,0.000007787234,0.002533021,0.8000032],"study_design_scores_gemma":[0.003560736,0.0002304303,0.0000351913,0.08896132,0.001893574,0.0002497703,0.0002756776,0.0001463448,0.01917457,0.00001189905,0.8843519,0.001108599],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003197809,0.9906024,0.0003381501,0.0001716984,0.0003222787,0.003398702,0.0001302055,0.00009811552,0.001740627],"genre_scores_gemma":[0.002309447,0.9859722,0.001258607,0.0005433622,0.004083128,0.00168541,0.001095978,0.0002951985,0.00275673],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8818189,"threshold_uncertainty_score":0.9996193,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2076068021","doi":"10.2174/187152009788680000","title":"Advances in Development of Inhibitors of 17β-Hydroxysteroid Dehydrogenases","year":2009,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; Centre Hospitalier Universitaire de Québec","keywords":"Hydroxysteroid Dehydrogenases; Chemistry; Computational biology; Biology; Biochemistry; Enzyme; Dehydrogenase","authors":[{"name":"Donald Poirier","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06501002984028083,"gpt":0.393356733159098,"spread":0.3283467033188172,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003240226,0.0003831822,0.002370613,0.0002547359,0.00001866074,0.000002156434,0.0001902475,0.0003325524,0.0001771595],"category_scores_gemma":[0.000103669,0.0003006279,0.0002257189,0.0005426231,0.0001359928,0.00005750391,0.00005080039,0.0004097148,0.000003304497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002917761,"about_ca_system_score_gemma":0.0008895179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001856497,"about_ca_topic_score_gemma":0.00001289871,"domain_scores_codex":[0.9969561,0.00003816319,0.001578085,0.0004133846,0.0007253828,0.000288889],"domain_scores_gemma":[0.9988006,0.00005655977,0.0006276389,0.0002866253,0.00009574629,0.0001327804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004625523,0.0002741397,0.001275398,0.03011499,0.00006395446,0.0001275506,0.0001499671,0.000005828361,0.001569923,6.393185e-7,0.00007603312,0.9662953],"study_design_scores_gemma":[0.001978665,0.00008429227,0.001594465,0.1414722,0.000473672,0.000112999,0.0001412934,0.00002568039,0.03839028,0.000005361202,0.8152916,0.0004295654],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06638064,0.9315128,0.000002814388,0.00001961979,0.00008210307,0.0003870662,0.000009565766,0.000009624456,0.001595794],"genre_scores_gemma":[0.05598671,0.9433569,0.0001491586,0.000043354,0.0001364435,0.00003437603,0.0001008909,0.00002923014,0.0001629117],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9658657,"threshold_uncertainty_score":0.9999446,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2125040825","doi":"10.2174/1871520611313070004","title":"Hitting the Golden TORget: Curcumin’s Effects on mTOR Signaling","year":2013,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of New Brunswick","funders":"National Cancer Institute","keywords":"Curcumin; PI3K/AKT/mTOR pathway; Chemistry; Pharmacology; Signal transduction; Cell biology; Biology","authors":[{"name":"Christopher S. Beevers","is_ca":true},{"name":"Hongyu Zhou","is_ca":false},{"name":"Shile Huang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03928805179868832,"gpt":0.3640867075644925,"spread":0.3247986557658042,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004416617,0.0006398919,0.001027941,0.00005451294,0.0001388335,0.00004045981,0.001387125,0.0007123051,0.0003816291],"category_scores_gemma":[0.0003971893,0.0004392201,0.0003630072,0.0003570827,0.0002723403,0.000004404109,0.0004283297,0.0008762255,0.0000873395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001765611,"about_ca_system_score_gemma":0.0003379165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006721904,"about_ca_topic_score_gemma":0.000001951098,"domain_scores_codex":[0.9969661,0.0001224862,0.0007694709,0.0009768612,0.0005602114,0.0006049144],"domain_scores_gemma":[0.9979538,0.0001863572,0.0004782322,0.001086084,0.00006929489,0.0002262563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001174518,0.0001648945,0.0001544371,0.01617127,0.0004181344,0.00003413521,0.00006110451,0.000002189784,0.04331648,0.000004665538,0.03520621,0.9044547],"study_design_scores_gemma":[0.0003757694,0.00004336397,0.00002369378,0.007066878,0.0003129578,0.00002163621,0.00003818182,0.000006471311,0.03762624,0.000008775071,0.954012,0.0004640096],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009835042,0.9868603,0.00005701063,0.0003592418,0.0004497753,0.001148,0.00006645733,0.00002727905,0.001196878],"genre_scores_gemma":[0.004853207,0.9858689,0.00007372604,0.0006683714,0.003808237,0.00149874,0.0005412095,0.0001164583,0.002571134],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9188058,"threshold_uncertainty_score":0.999806,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2167557320","doi":"10.2174/1871520614666140608150448","title":"Deoxypodophyllotoxin Isolated from Juniperus communis Induces Apoptosis in Breast Cancer Cells","year":2014,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Biological Activity of Diterpenoids and Biflavonoids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Moncton","funders":"Canadian Institutes of Health Research","keywords":"Apoptosis; Cancer; Lignan; MAPK/ERK pathway; Natural product; Cancer cell; Breast cancer; Traditional medicine; Biology; Chemistry; Medicine; Biochemistry; Botany; Signal transduction; Internal medicine","authors":[{"name":"Sami Benzina","is_ca":false},{"name":"Jason Harquail","is_ca":false},{"name":"Stéphanie Jean","is_ca":false},{"name":"Annie‐Pier Beauregard","is_ca":false},{"name":"Caitlyn Colquhoun","is_ca":false},{"name":"Madison Carroll","is_ca":false},{"name":"Allyson Bos","is_ca":false},{"name":"Christopher H. Gray","is_ca":false},{"name":"Gilles A. Robichaud","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01656664435939113,"gpt":0.2774306142152526,"spread":0.2608639698558614,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002545943,0.0003250093,0.0004402213,0.00003246506,0.00007358699,0.00002683701,0.0005875557,0.0004896924,0.0005960616],"category_scores_gemma":[0.0000289411,0.0002803819,0.00009605625,0.0002111381,0.0002322172,0.0000118028,0.0002330081,0.0005278512,0.000007557414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007061276,"about_ca_system_score_gemma":0.00005795329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003959819,"about_ca_topic_score_gemma":0.0002297548,"domain_scores_codex":[0.9981895,0.0001173662,0.0003883705,0.0006055788,0.0002295303,0.0004696567],"domain_scores_gemma":[0.9991953,0.00003557458,0.0001479248,0.000424173,0.00005127424,0.0001457355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001429906,0.0002369845,0.05773625,0.00004983866,0.0000501955,0.000003756287,0.00007135874,0.00003657674,0.9292389,3.251366e-7,0.0007517477,0.01168107],"study_design_scores_gemma":[0.001376381,0.00008441298,0.07762291,0.0002316558,0.00002399158,0.00000266641,0.0001390958,0.0002743614,0.9172196,0.00002498725,0.002603427,0.000396464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973275,0.0006413661,0.0000398456,0.0008558929,0.000228685,0.000134116,0.0001775718,0.00001606031,0.0005789277],"genre_scores_gemma":[0.9952151,0.00236215,0.00009065092,0.001394461,0.0005456829,0.00005903401,0.0001621043,0.00002634151,0.0001444709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01988666,"threshold_uncertainty_score":0.9999648,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2132487225","doi":"10.2174/187152012798764741","title":"Impact of Oncogenic Protein Tyrosine Phosphatases in Cancer","year":2012,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Protein tyrosine phosphatase; Receptor tyrosine kinase; Phosphorylation; Phosphatase; Carcinogenesis; G protein-coupled receptor; Biology; Receptor Protein-Tyrosine Kinases; Tyrosine phosphorylation; Protein phosphorylation; Cancer; Proto-oncogene tyrosine-protein kinase Src; Kinase; Signal transduction; Cancer research; Dual-specificity phosphatase; Tyrosine kinase; PTPN11; Receptor; Tyrosine; Cell biology; Biochemistry; Protein kinase A; Genetics","authors":[{"name":"Serge Hardy","is_ca":false},{"name":"Sofi G. Julien","is_ca":false},{"name":"Michel L. Tremblay","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06572485144887852,"gpt":0.4109783406509359,"spread":0.3452534892020574,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003977059,0.0008034263,0.00188428,0.0001210694,0.00003173142,0.0000126962,0.000845445,0.0006857663,0.0008973674],"category_scores_gemma":[0.0001596206,0.0006760874,0.0005503777,0.0005758972,0.0002687217,0.00001446576,0.0003427657,0.0006263906,0.000007579089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004434708,"about_ca_system_score_gemma":0.001376503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002015109,"about_ca_topic_score_gemma":0.0000599444,"domain_scores_codex":[0.9966006,0.00009971121,0.001174032,0.0008548009,0.0004523247,0.0008185101],"domain_scores_gemma":[0.9980029,0.00002195452,0.0008046528,0.0008584043,0.00009140091,0.0002206422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003213101,0.001280348,0.01702138,0.0490092,0.001194615,0.0001265174,0.00004644756,0.00005113793,0.03890279,0.000005807032,0.004191181,0.8878493],"study_design_scores_gemma":[0.002225984,0.000241821,0.001528863,0.0318441,0.0008457619,0.00004773023,0.00001419022,0.000003477374,0.5031188,0.000005803489,0.4587689,0.001354561],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0373917,0.9596263,0.000003635232,0.000009563908,0.0001637379,0.001026333,0.001689667,0.000010141,0.0000789097],"genre_scores_gemma":[0.03342828,0.962597,0.00005778342,0.00003207662,0.0007131287,0.0009807614,0.001748418,0.000108625,0.0003339107],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8864947,"threshold_uncertainty_score":0.9995691,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144290097","doi":"10.2174/187152008784220311","title":"Polynucleotide Kinase as a Potential Target for Enhancing Cytotoxicity by Ionizing Radiation and Topoisomerase I Inhibitors","year":2008,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"DNA repair; DNA damage; Biology; Topoisomerase; Biochemistry; Cell biology; DNA; DNA polymerase beta; DNA repair protein XRCC4; DNA polymerase; Base excision repair; Nucleotide excision repair","authors":[{"name":"Nina Bernstein","is_ca":true},{"name":"Feridoun Karimi‐Busheri","is_ca":false},{"name":"Aghdass Rasouli‐Nia","is_ca":false},{"name":"Rajam S. Mani","is_ca":false},{"name":"Grigory L. Dianov","is_ca":false},{"name":"J. N. Mark Glover","is_ca":false},{"name":"Michael Weinfeld","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01999890104138465,"gpt":0.3268092932797799,"spread":0.3068103922383953,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002022039,0.0005028418,0.0008913526,0.00006521504,0.000152614,0.00003071683,0.0002459269,0.0005152716,0.00006480773],"category_scores_gemma":[0.00006498557,0.0004968098,0.0002828154,0.0001427857,0.0001109349,0.00000855159,0.0001151884,0.0003398173,0.00000156605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001633135,"about_ca_system_score_gemma":0.0004185093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001194787,"about_ca_topic_score_gemma":0.00001035091,"domain_scores_codex":[0.9977778,0.00004809272,0.0006269866,0.0007997061,0.0002721218,0.0004752914],"domain_scores_gemma":[0.9990421,0.00002068767,0.0003782824,0.0003110449,0.00005484592,0.0001930212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001216164,0.0001743539,0.00003760451,0.007753127,0.0004385623,0.0000619874,0.00009484007,0.00001299911,0.4889549,0.000002671023,0.004979007,0.4973684],"study_design_scores_gemma":[0.001072667,0.000123733,0.000002225846,0.001935979,0.0002093939,0.00008301238,0.00005351099,0.00002363051,0.3625613,0.00001230323,0.6334055,0.000516758],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03973984,0.9583141,0.0004938816,0.00004247038,0.0004027905,0.0006714431,0.0002628729,0.00001329863,0.00005936115],"genre_scores_gemma":[0.01945138,0.9772445,0.00011818,0.0002710407,0.00121009,0.0002684264,0.0008730427,0.00008451541,0.0004788448],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6284265,"threshold_uncertainty_score":0.9997483,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988455775","doi":"10.2174/187152007784111340","title":"Oncogenic Fusion Tyrosine Kinases as Molecular Targets for Anti-Cancer Therapy","year":2007,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Tyrosine kinase; Kinase; Receptor tyrosine kinase; Cancer research; Cancer therapy; Cancer; Protein-Tyrosine Kinases; Targeted therapy; Fusion protein; Biology; Computational biology; Cell biology; Signal transduction; Genetics; Gene; Recombinant DNA","authors":[{"name":"Rosalind H. Gunby","is_ca":false},{"name":"Elisa Sala","is_ca":false},{"name":"Carmen Julia Tartari","is_ca":false},{"name":"Miriam Puttini","is_ca":false},{"name":"Carlo Gambacorti‐Passerini","is_ca":true},{"name":"Luca Mologni","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09394851989409721,"gpt":0.4398776877529862,"spread":0.345929167858889,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006602726,0.001178126,0.003540243,0.0002895469,0.0001413804,0.00003573806,0.0005925547,0.000979593,0.004177839],"category_scores_gemma":[0.00007779044,0.0009563024,0.001121812,0.0008010576,0.0002145206,0.00007692355,0.0001106644,0.001125931,0.00003036623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008873914,"about_ca_system_score_gemma":0.001468243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003440599,"about_ca_topic_score_gemma":0.000007030156,"domain_scores_codex":[0.9949088,0.00005827279,0.001385945,0.001408966,0.001116367,0.00112172],"domain_scores_gemma":[0.9975012,0.0001154857,0.0007563205,0.0009143645,0.000266312,0.0004463134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004877952,0.0005813984,0.0001001302,0.02084755,0.0009913268,0.0005289244,0.00007330767,0.000003876892,0.03268324,0.00001473589,0.003774619,0.9399131],"study_design_scores_gemma":[0.00494643,0.0002845812,0.00002730525,0.0223974,0.0009943635,0.0001089624,0.0000435416,0.00001118207,0.1105326,0.00003870929,0.8597969,0.0008179736],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01450456,0.9803017,0.0001904687,0.0002146459,0.001090124,0.002519647,0.0002732482,0.00009222607,0.0008134205],"genre_scores_gemma":[0.001175356,0.9884956,0.0001993757,0.002036369,0.002288405,0.001110928,0.0006862609,0.0002840562,0.003723624],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9390951,"threshold_uncertainty_score":0.9992887,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2125858978","doi":"10.2174/18715206113136660333","title":"Intracellular Expression of Inflammatory Proteins S100A8 and S100A9 Leads to Epithelial-mesenchymal Transition and Attenuated Aggressivity of Breast Cancer Cells","year":2014,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Moncton","funders":"Canadian Institutes of Health Research","keywords":"Biology; Epithelial–mesenchymal transition; Intracellular; Extracellular; Cancer research; Cell biology; Cancer cell; S100A9; Breast cancer; Signal transduction; Cancer; Metastasis; Immunology; Inflammation","authors":[{"name":"Kévin Cormier","is_ca":false},{"name":"Jason Harquail","is_ca":false},{"name":"Rodney J. Ouellette","is_ca":false},{"name":"Philippe A. Tessier","is_ca":false},{"name":"Roxann Guérrette","is_ca":false},{"name":"Gilles A. Robichaud","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007439029434651944,"gpt":0.2556164234870761,"spread":0.2481773940524242,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002555961,0.0001955676,0.000307156,0.00004086165,0.00003851589,0.000005463743,0.0001321016,0.0001901648,0.00007982417],"category_scores_gemma":[0.00003302553,0.0001629205,0.00004285262,0.00008924628,0.0002409559,0.00001010819,0.00008461119,0.0001249964,3.806223e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000171717,"about_ca_system_score_gemma":0.00006691794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001070076,"about_ca_topic_score_gemma":0.00001319907,"domain_scores_codex":[0.9987679,0.0000539083,0.0003363614,0.0003884301,0.0002216605,0.0002317664],"domain_scores_gemma":[0.9993493,0.00001064129,0.0001892065,0.0002266762,0.00009673566,0.0001274504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002009319,0.00006132184,0.02068126,0.0005305764,0.00001933431,0.000004595346,0.0001645913,0.00005232158,0.973128,8.817068e-7,0.0000788505,0.005077385],"study_design_scores_gemma":[0.001083673,0.00009216563,0.02411283,0.001075622,0.00002217918,0.000008258219,0.00007033906,0.00008118691,0.9730215,0.000007150139,0.0002473965,0.0001776722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979797,0.0007989731,0.0004521388,0.000266736,0.00005555193,0.000251376,0.0001382449,0.000005537019,0.00005171779],"genre_scores_gemma":[0.9983052,0.001079374,0.0001068571,0.00009884693,0.0002448554,0.00005475419,0.00001679005,0.0000196036,0.00007369498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004899713,"threshold_uncertainty_score":0.6643707,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3209724471","doi":"10.2174/1871520621666211026101252","title":"Role of Natural and Synthetic Flavonoids as Potential Aromatase Inhibitors in BreastCancer: Structure-Activity Relationship Perspective","year":2021,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Aromatase; Exemestane; Pharmacophore; Breast cancer; Cancer; Estrogen; Anastrozole; Pharmacology; Chemistry; Letrozole; Computational biology; Biology; Medicine; Biochemistry; Internal medicine","authors":[{"name":"Umang Shah","is_ca":false},{"name":"Aarti A. Patel","is_ca":false},{"name":"Samir Patel","is_ca":false},{"name":"Mehul Patel","is_ca":false},{"name":"Ashish Patel","is_ca":false},{"name":"Swayamprakash Patel","is_ca":false},{"name":"Sandip Patel","is_ca":false},{"name":"Rajesh Kumar Maheshwari","is_ca":false},{"name":"Andrew G. Mtewa","is_ca":false},{"name":"Karan Gandhi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02515695026118365,"gpt":0.3290916580868433,"spread":0.3039347078256596,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002655488,0.0006088446,0.002025238,0.00009473074,0.00006704054,0.00002721934,0.0003635618,0.0007811909,0.001363183],"category_scores_gemma":[0.0005832696,0.0004894403,0.0003227552,0.0004017862,0.0003904168,0.00009836513,0.0002349479,0.001580586,0.000001503497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007184716,"about_ca_system_score_gemma":0.0004600529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001200538,"about_ca_topic_score_gemma":0.00005122951,"domain_scores_codex":[0.9971613,0.0001451108,0.0007223715,0.001016632,0.0004772303,0.0004773246],"domain_scores_gemma":[0.9984083,0.0003267675,0.0005894335,0.0004492944,0.00007526702,0.0001509698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001515059,0.0006204373,0.008284272,0.02041914,0.0004325183,0.0002839637,0.0002546799,0.000008084218,0.0657435,0.00002309823,0.00006130392,0.9037175],"study_design_scores_gemma":[0.006172315,0.0001667463,0.02375998,0.193615,0.0046265,0.00174281,0.008198943,0.0003672595,0.6691839,0.001601525,0.08372067,0.006844365],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.3906627,0.6080765,1.788347e-7,0.00002389329,0.00008427685,0.0001198675,0.0002922461,0.00001357911,0.0007268196],"genre_scores_gemma":[0.5497611,0.4497803,0.000008969876,0.000006257416,0.0002384845,0.00003878674,0.00007838765,0.00002281424,0.00006486742],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.8968731,"threshold_uncertainty_score":0.9997557,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2010856476","doi":"10.2174/187152013804487263","title":"Cytoskeletal Alterations that Confer Resistance to Anti-tubulin Chemotherapeutics","year":2012,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Wellington Medical Research Foundation; Cancer Society of New Zealand; University of Victoria","keywords":"Tubulin; Microtubule; Cytoskeleton; Biology; Cell biology; Actin; Drug resistance; Microtubule-associated protein; Cell; Genetics","authors":[{"name":"Arun Kanakkanthara","is_ca":false},{"name":"Paul Teesdale‐Spittle","is_ca":false},{"name":"John H. Miller","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02666196652308085,"gpt":0.3163023434345267,"spread":0.2896403769114458,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002233337,0.0002721732,0.0002771561,0.0000370792,0.00008585912,0.00002318957,0.0003168312,0.000228791,0.0003163558],"category_scores_gemma":[0.00003843259,0.0002733176,0.00008990605,0.0001528723,0.0001074292,0.00001252131,0.000109139,0.0002262382,0.00002118957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006472409,"about_ca_system_score_gemma":0.0001151987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002180471,"about_ca_topic_score_gemma":0.00003461313,"domain_scores_codex":[0.9984081,0.00003027421,0.0003075323,0.0004215513,0.0002622166,0.0005702621],"domain_scores_gemma":[0.9991518,0.00001006774,0.00009559772,0.0004471906,0.00006901861,0.0002263588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004538285,0.0001590731,0.0840864,0.0001178251,0.00007594059,0.000006726381,0.0001838699,0.00004887614,0.9070938,0.00001428836,0.007621654,0.0005461141],"study_design_scores_gemma":[0.0007575986,0.00002208526,0.01379674,0.0001043548,0.00003665252,0.00001383403,0.0001497366,0.00003461773,0.8708653,0.00000574365,0.1138771,0.0003361754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923591,0.001795798,0.001273951,0.0005738066,0.0003058167,0.0002279151,0.00005848266,0.00001607554,0.003389063],"genre_scores_gemma":[0.9912653,0.00115186,0.0004195287,0.002571769,0.0008967463,0.00006311166,0.0001666613,0.00004266286,0.003422354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1062554,"threshold_uncertainty_score":0.9999719,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2509845441","doi":"10.2174/1871520616666160819103249","title":"Sesamol Induces Apoptosis by Altering Expression of Bcl-2 and Bax Proteins and Modifies Skin Tumor Development in Balb/c Mice","year":2016,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Sesame and Sesamin Research","field":"Agricultural and Biological Sciences","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Windsor","funders":"","keywords":"Apoptosis; Sesamol; Protein expression; Cell biology; BALB/c; Cancer research; Biology; Immunology; Gene; Genetics; Biochemistry; Immune system; Antioxidant","authors":[{"name":"Rishi Bhardwaj","is_ca":false},{"name":"SN Sanyal","is_ca":false},{"name":"Kim Vaiphei","is_ca":false},{"name":"Vandita Kakkar","is_ca":false},{"name":"Parneet Kaur Deol","is_ca":false},{"name":"Indu Pal Kaur","is_ca":false},{"name":"Tranum Kaur","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03682372499987858,"gpt":0.287174056470793,"spread":0.2503503314709145,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000230528,0.0001324223,0.0002202232,0.00001551535,0.0000541945,0.00001417196,0.0001695432,0.00007588887,0.0002143487],"category_scores_gemma":[0.00006366588,0.00005125229,0.00001491305,0.0001477244,0.0001375249,0.00009303403,0.0001278309,0.00009655426,6.347535e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003957874,"about_ca_system_score_gemma":0.00002076865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006282187,"about_ca_topic_score_gemma":0.00005435459,"domain_scores_codex":[0.9988386,0.00003299396,0.0002623459,0.0003135336,0.0002920803,0.0002604346],"domain_scores_gemma":[0.9996652,0.0001003676,0.00007611318,0.00004260808,0.00002856823,0.00008714698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003073118,0.00005122357,0.05494703,0.00009841674,0.000004552046,0.000003481333,0.0001941759,1.833053e-7,0.9144414,2.219623e-7,0.0001297177,0.03009883],"study_design_scores_gemma":[0.0003667364,0.00003026406,0.09996118,0.0006984924,0.000002152548,0.000002417115,0.0005913283,0.000007018185,0.8977318,0.000007774152,0.00048922,0.0001116424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986863,0.0006651213,0.000002160749,0.0003231397,0.00001956315,0.0001599125,0.00001632322,0.000006697749,0.0001208421],"genre_scores_gemma":[0.9986254,0.0009307108,0.00005330262,0.00005727111,0.00005804989,0.00006334423,0.000006341014,0.000001427244,0.0002041274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04501416,"threshold_uncertainty_score":0.2346968,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2030908978","doi":"10.2174/187152011796011109","title":"Therapeutic Potential of Targeting Glypican-3 in Hepatocellular Carcinoma","year":2011,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research","keywords":"Glypican 3; Hepatocellular carcinoma; Cancer research; Monoclonal antibody; Immunohistochemistry; Oncofetal antigen; Medicine; Pathology; Antibody; Biology; Immunology","authors":[{"name":"Mark Allegretta","is_ca":false},{"name":"Jorge Filmus","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1284621606049395,"gpt":0.3375057856867938,"spread":0.2090436250818543,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005184371,0.0007569555,0.003076911,0.0002975421,0.00003826772,0.000009111753,0.0004304008,0.0007129324,0.001661327],"category_scores_gemma":[0.00005070111,0.000625424,0.0006977286,0.0007121796,0.0002286183,0.00005480942,0.0001232147,0.001074695,0.00001858021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004197777,"about_ca_system_score_gemma":0.0007940046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007059223,"about_ca_topic_score_gemma":0.000003938683,"domain_scores_codex":[0.9962059,0.0001519356,0.00152046,0.0008403608,0.000574505,0.0007068691],"domain_scores_gemma":[0.9984002,0.00005857164,0.0006072265,0.0006061643,0.00009082258,0.000237081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001285741,0.0006610912,0.6583686,0.0550507,0.0005699454,0.002682302,0.0002867942,2.779723e-7,0.0006949514,0.000003225379,0.0001950836,0.2813585],"study_design_scores_gemma":[0.01580821,0.0008333328,0.02083836,0.1420757,0.01718923,0.0007900383,0.000758054,0.001546965,0.02970467,0.00007085952,0.7665048,0.003879774],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1818662,0.8159893,0.000005924536,0.00002001966,0.0001929051,0.0009315838,0.00003532746,0.00002268715,0.0009360372],"genre_scores_gemma":[0.3984521,0.6005074,0.00004411088,0.00003495764,0.0002551787,0.000175394,0.0002213015,0.00007148554,0.0002380977],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7663097,"threshold_uncertainty_score":0.9996197,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2110761419","doi":"10.2174/187152006776119171","title":"3-Carboranyl Thymidine Analogues (3CTAs) and Other Boronated Nucleosides for Boron Neutron Capture Therapy","year":2006,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Boron Compounds in Chemistry","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"National Cancer Institute","keywords":"Thymidine kinase; Thymidine; Boron; Chemistry; Neutron capture; Molecule; Nucleoside; Radiochemistry; Enzyme; Biochemistry; Cancer research; Combinatorial chemistry; Pharmacology; Medicine; In vitro; Organic chemistry; Virology; Virus","authors":[{"name":"Youngjoo Byun","is_ca":false},{"name":"Sureshbabu Narayanasamy","is_ca":false},{"name":"Jayaseharan Johnsamuel","is_ca":false},{"name":"Achintya K. Bandyopadhyaya","is_ca":false},{"name":"Rohit Tiwari","is_ca":false},{"name":"Ashraf Al Madhoun","is_ca":true},{"name":"Rolf F. Barth","is_ca":false},{"name":"Staffan Eriksson","is_ca":false},{"name":"Werner Tjarks","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09608343717535014,"gpt":0.4039595894940675,"spread":0.3078761523187173,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004543484,0.001181289,0.003153047,0.0001350511,0.0001132665,0.00004795666,0.0005367668,0.001248395,0.0003915319],"category_scores_gemma":[0.00009130363,0.0009641345,0.0005040257,0.0004444324,0.0004689519,0.00008784412,0.0001145806,0.001412871,0.000003790166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006042179,"about_ca_system_score_gemma":0.0006193314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004323172,"about_ca_topic_score_gemma":0.00003436962,"domain_scores_codex":[0.9957208,0.00006578488,0.001271089,0.001364579,0.0006984703,0.0008792846],"domain_scores_gemma":[0.9977663,0.000217148,0.0006666851,0.000883472,0.0001594074,0.0003069514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001071417,0.001822366,0.01946167,0.2032341,0.003844579,0.0008054452,0.0004485644,0.00001125402,0.01502213,0.00001670152,0.05805447,0.6962073],"study_design_scores_gemma":[0.003831611,0.00009346211,0.000698032,0.02086899,0.001369998,0.0001944273,0.00009410448,0.00003818555,0.004173767,0.00001702367,0.9677084,0.0009120135],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01514683,0.9792991,0.000005384798,0.000268444,0.0003114635,0.001395253,0.0007047231,0.0001262598,0.002742538],"genre_scores_gemma":[0.008756691,0.9852647,0.0002222439,0.000633434,0.001828732,0.0005200056,0.001045334,0.0002780549,0.001450863],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9096539,"threshold_uncertainty_score":0.9992809,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2131397188","doi":"10.2174/187152012798764679","title":"Selective Activation of Intracellular Signalling Pathways in Dendritic Cells for Cancer Immunotherapy","year":2012,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; Versus Arthritis","keywords":"Signalling pathways; Cancer immunotherapy; Intracellular; Immunotherapy; Signalling; Signal transduction; Cell biology; Cancer research; Chemistry; Biology; Immune system; Immunology","authors":[{"name":"Frederick Arce","is_ca":false},{"name":"Grazyna Kochan","is_ca":false},{"name":"Karine Breckpot","is_ca":false},{"name":"Holly Stephenson","is_ca":false},{"name":"David Escors","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05426983162097877,"gpt":0.3343114113233641,"spread":0.2800415797023854,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000689545,0.0005713669,0.001983181,0.0002379435,0.0000726888,0.000008460752,0.0005119217,0.0009594501,0.0007714975],"category_scores_gemma":[0.00005592755,0.0005136524,0.0003671753,0.0004410157,0.0002462431,0.0001128523,0.00004555683,0.001061616,0.000007005617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005157989,"about_ca_system_score_gemma":0.0006614648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003903964,"about_ca_topic_score_gemma":0.00000739458,"domain_scores_codex":[0.9971723,0.0002947681,0.001203037,0.0005085574,0.0001085577,0.0007127861],"domain_scores_gemma":[0.9982755,0.0004985383,0.0007648663,0.0003285909,0.0001085752,0.00002392797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003789258,0.0002874882,0.00009454146,0.01051074,0.000665843,0.000003110805,0.0006987113,0.00001238133,0.628047,0.000003038585,0.00008523611,0.359213],"study_design_scores_gemma":[0.001890062,0.00006322633,0.00005113134,0.01598471,0.0002719951,0.000009601031,0.0001621972,0.000002927821,0.6729857,0.000009863054,0.3081263,0.0004422324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03476617,0.9632272,0.0001081634,0.00001225198,0.0007052908,0.0009941988,0.0001145799,0.00002682496,0.0000453774],"genre_scores_gemma":[0.05161448,0.946458,0.00002537357,0.00004711247,0.0001552761,0.0007871663,0.0002058874,0.0001099197,0.0005968219],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3587708,"threshold_uncertainty_score":0.9997315,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2091087622","doi":"10.2174/187152007781058622","title":"Harnessing Telomerase in Cancer Therapeutics","year":2007,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Jewish General Hospital; McGill University","funders":"Jewish General Hospital","keywords":"Telomerase; Telomere; Telomerase reverse transcriptase; Cancer; Biology; Cancer research; Genetic enhancement; Cancer cell; Oligonucleotide; Cancer immunotherapy; Gene; Immunotherapy; Computational biology; Genetics","authors":[{"name":"Johans Fakhoury","is_ca":true},{"name":"Graeme Nimmo","is_ca":false},{"name":"Chantal Autexier","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1147767581882077,"gpt":0.4320263965930206,"spread":0.3172496384048129,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003590194,0.0005739179,0.001116425,0.0001381413,0.00004541828,0.00002608993,0.0006175904,0.0007762611,0.0003428019],"category_scores_gemma":[0.00002907192,0.0005070741,0.0002609601,0.0003936662,0.000165091,0.000006766776,0.0001601934,0.0007656002,0.00001149625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002149127,"about_ca_system_score_gemma":0.0006418574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002709537,"about_ca_topic_score_gemma":0.0001069643,"domain_scores_codex":[0.9973453,0.00006449098,0.0008231196,0.0008178145,0.0003271372,0.000622093],"domain_scores_gemma":[0.9989665,0.00002313273,0.0003205638,0.0005051731,0.00006900321,0.0001156584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004073431,0.0001500292,0.002609194,0.007332582,0.0002345535,0.0001582384,0.00006456367,0.00001604115,0.007575011,2.001338e-7,0.001286077,0.9805328],"study_design_scores_gemma":[0.0006384705,0.00003666287,0.0001930315,0.01442183,0.00024754,0.00003001998,0.00008701881,0.00001017956,0.02106971,0.00000234823,0.9625892,0.0006739892],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05359186,0.9446087,0.00001448719,0.00002673223,0.0004382899,0.0002607888,0.0000597418,0.000008937954,0.0009904506],"genre_scores_gemma":[0.005969875,0.9902501,0.00002247752,0.0005417226,0.0009951055,0.0001515329,0.0002690345,0.00007298386,0.001727225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9798588,"threshold_uncertainty_score":0.9997381,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2319054744","doi":"10.2174/1871520614666140309231144","title":"Glycosylated Antitumor Ether Lipids: Activity and Mechanism of Action","year":2014,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Chemistry; Apoptosis; Biochemistry; Vacuole; Programmed cell death; Mechanism of action; Cancer cell; Cytotoxicity; Cytotoxic T cell; Biology; In vitro; Cancer; Cytoplasm","authors":[{"name":"Gilbert Arthur","is_ca":false},{"name":"Robert Bittman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06699024182981261,"gpt":0.4082935708201583,"spread":0.3413033289903457,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004795026,0.0003838775,0.001040059,0.00009967021,0.0000485393,0.00001528129,0.0003075096,0.0006844296,0.0003190163],"category_scores_gemma":[0.0001576973,0.0003343723,0.000183911,0.0002433745,0.0001698893,0.00000642362,0.0001816961,0.0005818845,0.00000617412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006217454,"about_ca_system_score_gemma":0.0002847802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001422585,"about_ca_topic_score_gemma":0.00002031603,"domain_scores_codex":[0.9979908,0.0001454311,0.0004841776,0.0006353608,0.0004032688,0.000340909],"domain_scores_gemma":[0.9988944,0.00002559616,0.000385735,0.0004655061,0.00009574173,0.0001330232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001553125,0.0002213616,0.0002272884,0.03991107,0.0004075411,0.00002474816,0.00002930643,0.000004383218,0.233883,0.00002195482,0.0009125379,0.7242015],"study_design_scores_gemma":[0.001148737,0.0001390581,0.00009554052,0.006344515,0.0002192633,0.00005054262,0.00002551442,0.00009277157,0.230896,0.0000251733,0.7604116,0.0005512417],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09413019,0.9030235,0.0002766379,0.00003271082,0.0002676165,0.0006904581,0.00007587505,0.00001567273,0.001487345],"genre_scores_gemma":[0.06845994,0.9295807,0.00004174714,0.00003172389,0.0004121106,0.00008646637,0.0001399711,0.0000503817,0.001196902],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7594991,"threshold_uncertainty_score":0.9999108,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2125448583","doi":"10.2174/187152007781668689","title":"Targeting Aberrant TGF-β Signaling in Pre-Clinical Models of Cancer","year":2007,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Canadian Breast Cancer Research Alliance; Cancer Research Society; Breast Cancer Alliance","keywords":"Cancer research; Signal transduction; Cancer; Metastasis; Biology; Tumor microenvironment; Transforming growth factor; Extracellular matrix; Cell signaling; Immune system; Cell biology; Immunology","authors":[{"name":"Anna Mourskaia","is_ca":true},{"name":"Jason J. Northey","is_ca":false},{"name":"Peter M. Siegel","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1060525366678882,"gpt":0.4479213180022914,"spread":0.3418687813344031,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00125585,0.0006686393,0.001986692,0.0001311105,0.00004256024,0.00001294953,0.0008854138,0.001012576,0.000325502],"category_scores_gemma":[0.0002815418,0.000622988,0.0004917706,0.0003798025,0.0003097891,0.000008652775,0.0002720761,0.0009534531,0.000002470765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001634039,"about_ca_system_score_gemma":0.001170518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003557352,"about_ca_topic_score_gemma":0.0000407861,"domain_scores_codex":[0.9951256,0.0001669147,0.002277119,0.001121664,0.0005908103,0.0007178864],"domain_scores_gemma":[0.9979601,0.0001215844,0.0009605502,0.000609157,0.0001273245,0.0002212867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006262686,0.001924233,0.03461334,0.1145489,0.002225187,0.0004653624,0.0005230396,0.01421726,0.0422514,0.000002076255,0.005471651,0.7831312],"study_design_scores_gemma":[0.005495283,0.0002146835,0.000910984,0.1267152,0.002225028,0.00003281758,0.0002365471,0.001045798,0.08831476,0.00003810448,0.771179,0.003591767],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1091501,0.8895841,0.000102328,0.000005838865,0.0003574362,0.000448783,0.0001093112,0.00001314858,0.0002289675],"genre_scores_gemma":[0.03931126,0.9580741,0.0001922485,0.00009773525,0.001254349,0.0001860204,0.0004053981,0.0001083011,0.000370624],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7795395,"threshold_uncertainty_score":0.9996222,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2031220986","doi":"10.2174/187152011797655050","title":"Hypoxia-Inducible Factors and Sphingosine 1-Phosphate Signaling","year":2011,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Cancer Research; Université de Toulouse; Institut National Du Cancer; Association pour la Recherche sur les Tumeurs de la Prostate; Ligue Contre le Cancer; Association pour la Recherche sur le Cancer","keywords":"Angiogenesis; Sphingosine-1-phosphate; Sphingosine kinase 1; Sphingosine; Cancer research; Hypoxia (environmental); Hypoxia-inducible factors; PTEN; Sphingosine kinase; Transcription factor; Biology; Signal transduction; Regulator; Kinase; Sphingolipid; Cell biology; Chemistry; PI3K/AKT/mTOR pathway; Biochemistry; Receptor; Gene","authors":[{"name":"Olivier Cuvillier","is_ca":false},{"name":"Isabelle Ader","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06283560590419697,"gpt":0.3386893520133181,"spread":0.2758537461091211,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003519516,0.0007801343,0.001609008,0.0000903848,0.00009657594,0.0000336313,0.0005358405,0.0007571547,0.0003876189],"category_scores_gemma":[0.0001038877,0.0006556453,0.0003331544,0.0002633526,0.0002299788,0.00001014296,0.0002716224,0.0006564849,0.000005962414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007339062,"about_ca_system_score_gemma":0.0004457339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000288874,"about_ca_topic_score_gemma":0.00001305019,"domain_scores_codex":[0.9971169,0.00006019253,0.0007574132,0.001118335,0.0002956541,0.0006514764],"domain_scores_gemma":[0.998537,0.00002400519,0.0004481746,0.0006376115,0.00006913293,0.0002840896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009450588,0.000307686,0.00238873,0.03271619,0.001221148,0.00005110838,0.0003813614,0.000006257296,0.04768077,0.000007877381,0.009590685,0.9055537],"study_design_scores_gemma":[0.0006439604,0.00003497734,0.0001344474,0.004433609,0.0005709418,0.00003993703,0.00005947045,0.000001043627,0.03978128,0.000005874477,0.953625,0.0006695205],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05390472,0.9435391,0.00001593949,0.000008223614,0.001263509,0.0003545914,0.00009910717,0.00001960387,0.0007951501],"genre_scores_gemma":[0.004349936,0.9904326,0.00005851971,0.0001197298,0.002854823,0.0001037609,0.0003673868,0.0001122458,0.001601049],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9440343,"threshold_uncertainty_score":0.9995895,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3130728587","doi":"10.2174/1871520621666210223095021","title":"Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential","year":2021,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Hops Chemistry and Applications","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":17,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"","keywords":"Xanthohumol; Cancer; Pharmacology; In vivo; Medicine; Cancer research; Chemistry; Biology; Biotechnology; Internal medicine","authors":[{"name":"Hardeep Singh Tuli","is_ca":false},{"name":"Vaishali Aggarwal","is_ca":false},{"name":"Gaurav Parashar","is_ca":false},{"name":"Diwakar Aggarwal","is_ca":false},{"name":"Nidarshana Chaturvedi Parashar","is_ca":false},{"name":"Muobarak J. Tuorkey","is_ca":false},{"name":"Mehmet Varol","is_ca":false},{"name":"Katrin Sak","is_ca":false},{"name":"Manoj Kumar","is_ca":false},{"name":"Harpal S. Buttar","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1820820773905198,"gpt":0.510008469362196,"spread":0.3279263919716762,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005312435,0.0008564335,0.002345374,0.00008956094,0.0002643407,0.00004788163,0.000753129,0.001070996,0.004341414],"category_scores_gemma":[0.000101931,0.0007224064,0.0003760663,0.0008658019,0.0004717561,0.00008222937,0.0001912485,0.002943074,0.0000493404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002314885,"about_ca_system_score_gemma":0.001166477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002205173,"about_ca_topic_score_gemma":0.000001829436,"domain_scores_codex":[0.9961868,0.0002624739,0.001038389,0.00114091,0.0004796049,0.0008918332],"domain_scores_gemma":[0.9980234,0.0002371472,0.0006076355,0.0005809733,0.0001342412,0.0004166075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000185565,0.002505647,0.00208014,0.1108911,0.005266023,0.005795288,0.0005843412,0.0007080851,0.02308561,0.00004381625,0.01124278,0.8376116],"study_design_scores_gemma":[0.001336914,0.00001414644,0.00003277873,0.008700564,0.003599757,0.0005431554,0.00009710413,0.00009048327,0.01613642,0.000004718755,0.9686396,0.000804347],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01221552,0.983121,0.00006827235,0.0001126603,0.0005195936,0.0006864484,0.0004349891,0.00008445463,0.002757034],"genre_scores_gemma":[0.008642927,0.9860244,0.0001138604,0.0003222117,0.001346139,0.0004946234,0.0008731347,0.0001063862,0.002076313],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9573968,"threshold_uncertainty_score":0.9995227,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2134096744","doi":"10.2174/187152011796817637","title":"Coordinated Expression of Pax-5 and FAK1 in Metastasis","year":2011,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Moncton","funders":"Canadian Institutes of Health Research","keywords":"Expression (computer science); Metastasis; Biology; Cancer research; Cancer; Computer science; Genetics","authors":[{"name":"Nicolas Crapoulet","is_ca":true},{"name":"Pierre O'Brien","is_ca":false},{"name":"Rodney J. Ouellette","is_ca":false},{"name":"Gilles A. Robichaud","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1028615886877149,"gpt":0.4026923016102898,"spread":0.299830712922575,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003535645,0.0003982359,0.002306651,0.0002895344,0.00002112665,0.00000507857,0.0001643596,0.0003746207,0.002116805],"category_scores_gemma":[0.0001157635,0.0003061572,0.0002783705,0.000661776,0.0002011808,0.00004640988,0.00009735189,0.0006825997,0.000005088081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000137865,"about_ca_system_score_gemma":0.000224782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001975792,"about_ca_topic_score_gemma":0.000006945684,"domain_scores_codex":[0.9977974,0.0000791276,0.0009718856,0.0005246921,0.000327348,0.0002995824],"domain_scores_gemma":[0.9988934,0.00005060764,0.0004479657,0.00035898,0.00006852185,0.0001805408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001333923,0.000927665,0.006691394,0.1418014,0.0006521289,0.0008971961,0.0004021488,8.10821e-7,0.006928163,0.00000378518,0.003664696,0.8378972],"study_design_scores_gemma":[0.005848311,0.0001157365,0.001100205,0.4729874,0.004121941,0.0002360379,0.0005963256,0.00003257066,0.05304842,0.00002048288,0.4607907,0.00110182],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02112405,0.9760535,0.000006411156,0.00003462094,0.00003087789,0.0003000043,0.00008254951,0.00001688097,0.00235108],"genre_scores_gemma":[0.02602168,0.9726583,0.00005724355,0.00008453745,0.00009753472,0.00007456035,0.0001999443,0.00003571751,0.0007704451],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8367954,"threshold_uncertainty_score":0.999939,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2167536742","doi":"10.2174/1871520615666141216145417","title":"Lessons from Nature: Sources and Strategies for Developing AMPK Activators for Cancer Chemotherapeutics","year":2015,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"AMPK; Phenformin; mTORC1; Metformin; Protein kinase A; AMP-activated protein kinase; Signal transduction; PI3K/AKT/mTOR pathway; Cell growth; Chemistry; Cancer cell; Cancer research; Pharmacology; Cell biology; Cancer; Kinase; Biology; Medicine; Biochemistry; Internal medicine; Endocrinology","authors":[{"name":"Richard T Arkwright","is_ca":false},{"name":"Rahul Deshmukh","is_ca":false},{"name":"Nikhil Adapa","is_ca":false},{"name":"Ryan Stevens","is_ca":false},{"name":"Emily Zonder","is_ca":false},{"name":"Zhongyu Zhang","is_ca":false},{"name":"Pershang Farshi","is_ca":false},{"name":"Reda Saber Ibrahim Ahmed","is_ca":false},{"name":"Hossny A. El-Banna","is_ca":false},{"name":"Tak Hang Chan","is_ca":false},{"name":"Q. Ping Dou","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09930168544716675,"gpt":0.4357060920519754,"spread":0.3364044066048086,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003058075,0.0006144869,0.00139473,0.0000477475,0.00009589844,0.00006262157,0.0004824709,0.001080929,0.00004320904],"category_scores_gemma":[0.00006848128,0.0005317064,0.0002468901,0.0001464688,0.0001938489,0.00001214402,0.0001094823,0.0004682838,3.622967e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001525217,"about_ca_system_score_gemma":0.001798986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009603822,"about_ca_topic_score_gemma":0.00005826479,"domain_scores_codex":[0.9976915,0.00003905226,0.0005416917,0.0009107802,0.0002737237,0.0005432517],"domain_scores_gemma":[0.9988154,0.00006275283,0.0004324575,0.0003750278,0.0001690429,0.0001452977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006495114,0.00003668905,0.0001070058,0.0122489,0.0007573825,0.000001383484,0.0001303595,0.000003878667,0.001383855,0.00001630557,0.004507859,0.9807414],"study_design_scores_gemma":[0.001084759,0.00002393356,0.00001438106,0.003713025,0.0006493187,0.000002079368,0.0002916596,0.00000832155,0.01968679,0.0001755514,0.9737412,0.0006089775],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01302037,0.9841844,0.0002606015,0.00005691277,0.0006332835,0.0007119845,0.001052129,0.00001375388,0.0000665456],"genre_scores_gemma":[0.0008576922,0.9933924,0.0004069743,0.0006027381,0.002394972,0.001105275,0.0008717866,0.0001131852,0.0002549914],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9801325,"threshold_uncertainty_score":0.9997134,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2889027857","doi":"10.2174/1871520618666180816142821","title":"Modulation of Mitochondrial and Epigenetic Targets by Polyphenols-rich Extract from Araucaria angustifolia in Larynx Carcinoma","year":2018,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Plant-Derived Bioactive Compounds","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Centre for Addiction and Mental Health","keywords":"Araucaria; Epigenetics; Biology; Botany; Polyphenol; Genetics; Biochemistry; Gene","authors":[{"name":"Cátia Santos Branco","is_ca":false},{"name":"Angela Duong","is_ca":true},{"name":"Alencar Kolinski Machado","is_ca":false},{"name":"Gustavo Scola","is_ca":true},{"name":"Ana C. Andreazza","is_ca":true},{"name":"Mirian Salvador","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01909464641687218,"gpt":0.2779783544213627,"spread":0.2588837080044905,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001005168,0.0003175597,0.0004887173,0.00006257598,0.00005112206,0.00001720517,0.0003346496,0.0003108398,0.001481841],"category_scores_gemma":[0.0001021375,0.0003307681,0.00004570994,0.0002104838,0.0003264034,0.0001081757,0.0001074329,0.0004018534,0.000003795253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002138326,"about_ca_system_score_gemma":0.0001166482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002389347,"about_ca_topic_score_gemma":0.0001194491,"domain_scores_codex":[0.9979207,0.00003053548,0.0005486162,0.0006341261,0.0004334651,0.0004325534],"domain_scores_gemma":[0.9990634,0.00009058502,0.0002622101,0.0003629227,0.000080921,0.0001399081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001664278,0.0001096925,0.2638158,0.0001058452,0.00004167693,0.00003310976,0.0003652257,0.00000568044,0.7331933,2.355302e-7,0.0007177563,0.001445319],"study_design_scores_gemma":[0.00186636,0.00002100441,0.2414297,0.0002481559,0.00004125584,0.000006680109,0.0002159033,0.001479214,0.7541108,0.00005896164,0.0002638152,0.0002580883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950005,0.002350841,0.00006669285,0.00007762979,0.0002704463,0.0001026741,0.0003470194,0.00002037988,0.001763802],"genre_scores_gemma":[0.9980859,0.0002677764,0.0002949477,0.00006324468,0.000764457,0.00002507531,0.0002615326,0.00003143136,0.0002056918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02238603,"threshold_uncertainty_score":0.9999144,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4406189900","doi":"10.2174/0118715206348821241119100134","title":"Pioneering a New Era in Oral Cancer Treatment with Electrospun Nanofibers: A Comprehensive Insight","year":2025,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Nanofiber; Drug delivery; Nanotechnology; Therapeutic modalities; Electrospinning; Cancer; Biocompatible material; Medicine; Materials science; Biomedical engineering","authors":[{"name":"Devika Tripathi","is_ca":false},{"name":"Tanya Gupta","is_ca":false},{"name":"Awani Kumar","is_ca":false},{"name":"Prashant Kumar Pandey","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03995356240811737,"gpt":0.3634472784962999,"spread":0.3234937160881826,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001663149,0.0009063868,0.002486742,0.0002591058,0.0001051585,0.00005896485,0.0008735523,0.0005329996,0.000997368],"category_scores_gemma":[0.00001442549,0.0006774853,0.000209416,0.001905127,0.000313084,0.0001063215,0.0001614348,0.0007519817,0.00002013794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002726341,"about_ca_system_score_gemma":0.003586887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002199345,"about_ca_topic_score_gemma":0.0002927201,"domain_scores_codex":[0.9957483,0.00009693507,0.001089501,0.00131348,0.0007319899,0.001019776],"domain_scores_gemma":[0.9982411,0.0002044949,0.0004670715,0.0007007316,0.00008629438,0.0003003273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001617349,0.0007998498,0.0006057009,0.03439986,0.000553785,0.0004456613,0.0006322007,0.00003089227,0.04720539,0.00002394062,0.005983569,0.9091574],"study_design_scores_gemma":[0.002548783,0.0001667146,0.00008559337,0.04649585,0.0007890725,0.00005554899,0.00003681407,0.00001874128,0.03124093,0.00003434834,0.917503,0.001024587],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002162996,0.9948355,0.0002572315,0.0002487754,0.00031503,0.001283653,0.0001299438,0.00008963253,0.0006772677],"genre_scores_gemma":[0.0001172561,0.992188,0.002223365,0.0002778491,0.0003803968,0.001954033,0.0001541954,0.00007391056,0.002630997],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9115195,"threshold_uncertainty_score":0.9999158,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2134152344","doi":"10.2174/1871520611009030250","title":"New Medical Strategies for Midgut Carcinoids","year":2010,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Kungl. Vetenskaps- och Vitterhets-Samhället i Göteborg; Royal Society; Cancer Research Society","keywords":"Cancer research; Radionuclide therapy; Somatostatin receptor; PI3K/AKT/mTOR pathway; Medicine; Angiogenesis; Receptor tyrosine kinase; Somatostatin; Neuroendocrine tumors; Tyrosine kinase; Octreotide; Chemotherapy; Receptor; Biology; Internal medicine; Signal transduction","authors":[{"name":"Ola Nilsson","is_ca":false},{"name":"Yvonne Arvidsson","is_ca":false},{"name":"Viktor Johanson","is_ca":false},{"name":"Eva Forssell‐Aronsson","is_ca":false},{"name":"Håkan Ahlman","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09080618511125982,"gpt":0.4672958888446471,"spread":0.3764897037333872,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004331133,0.0008290406,0.003006516,0.0002169225,0.00007810191,0.00004814835,0.001000574,0.0003233488,0.004005793],"category_scores_gemma":[0.001000516,0.0006470198,0.0006050405,0.0005430204,0.0003994158,0.0001270869,0.0002244279,0.003387827,0.00003159435],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003114258,"about_ca_system_score_gemma":0.007749891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002411557,"about_ca_topic_score_gemma":0.00005789629,"domain_scores_codex":[0.994528,0.00006429966,0.001193966,0.001129127,0.001912677,0.001171924],"domain_scores_gemma":[0.9971343,0.0003317066,0.0003673137,0.0008666539,0.0001557022,0.001144318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001102566,0.0001883667,0.0003858547,0.08889546,0.00023765,0.005194122,0.00003503837,4.519796e-7,0.0002179636,0.0000176091,0.02755027,0.877167],"study_design_scores_gemma":[0.002347611,0.0001292827,0.00002939985,0.02386318,0.0006556323,0.001738408,0.0001054067,0.00001140325,0.0007715467,0.00006186221,0.9698157,0.0004705095],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001018297,0.9921106,0.00005893665,0.0006431575,0.0007285284,0.001630388,0.0000916203,0.00008803086,0.003630403],"genre_scores_gemma":[0.000256443,0.9867347,0.0004245339,0.0003425377,0.003220573,0.0006109462,0.000279577,0.000162869,0.007967838],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9422655,"threshold_uncertainty_score":0.9995981,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2164253396","doi":"10.2174/1871520615666150507120801","title":"Prognostic Value and Clinicopathological Differences of Bmi1 in Gastric Cancer: A Meta-analysis","year":2016,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; BMI1; Meta-analysis; Cancer; Random effects model; Oncology; Metastasis; Gastroenterology","authors":[{"name":"Bin Yuan","is_ca":false},{"name":"Hong Zhao","is_ca":false},{"name":"Xiaofeng Xue","is_ca":false},{"name":"Jin Zhou","is_ca":false},{"name":"Xu Wang","is_ca":false},{"name":"Ye Han","is_ca":false},{"name":"Li‐Feng Zhang","is_ca":false},{"name":"Xiaobo Guo","is_ca":false},{"name":"Qiaoming Zhi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.167250318136791,"gpt":0.4515604005706547,"spread":0.2843100824338637,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009826475,0.0005466412,0.003224497,0.0002433166,0.0000312982,0.00001335935,0.0006867158,0.0005794016,0.0007311034],"category_scores_gemma":[0.0002574138,0.000351286,0.0008974869,0.000828731,0.0004424073,0.000004202666,0.0002654754,0.0005321909,0.000002044327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007656675,"about_ca_system_score_gemma":0.0005618721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009826052,"about_ca_topic_score_gemma":0.00009111627,"domain_scores_codex":[0.9963725,0.0004170473,0.001093673,0.001054999,0.0005213843,0.0005403814],"domain_scores_gemma":[0.998463,0.0001550208,0.0005416114,0.0005954615,0.00008429711,0.000160604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001069347,0.001141735,0.1838894,0.03164354,0.06375058,0.000390545,0.0001167329,0.0000569304,0.01431447,0.000002311869,0.0004275181,0.7031968],"study_design_scores_gemma":[0.01543657,0.008802982,0.04379848,0.03755859,0.6254991,0.0003286489,0.00039672,0.0002397157,0.05630497,0.0002157096,0.2019441,0.009474495],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1459288,0.8532134,0.000009692601,0.00004486908,0.00004392674,0.0004369806,0.0002455675,0.000004640755,0.00007215289],"genre_scores_gemma":[0.06787281,0.9308357,0.00002556072,0.00005490386,0.0001923964,0.0005525292,0.00009588844,0.00003457925,0.0003356113],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6937224,"threshold_uncertainty_score":0.9998939,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2789587766","doi":"10.2174/1871520618666180307130158","title":"Parallel Solid-Phase Synthesis using a New Diethylsilylacetylenic Linker and Leading to Mestranol Derivatives with Potent Antiproliferative Activities on Multiple Cancer Cell Lines","year":2018,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"LNCaP; In vivo; Linker; Chemistry; Potency; Cancer; Mestranol; Prostate cancer; Ovarian cancer; In vitro; Pancreatic cancer; Stereochemistry; Cancer research; Population; Biochemistry; Internal medicine; Medicine; Biology","authors":[{"name":"Raphaël Dutour","is_ca":true},{"name":"René Maltais","is_ca":true},{"name":"Martin Perreault","is_ca":true},{"name":"Jenny Roy","is_ca":true},{"name":"Donald Poirier","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03380921490668006,"gpt":0.3615147736018586,"spread":0.3277055586951785,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001038393,0.000337939,0.0004497708,0.00003537965,0.0001278879,0.00003288696,0.0001621679,0.0001684695,0.0001416617],"category_scores_gemma":[0.0001334294,0.0002691485,0.00008152542,0.0001710592,0.0002340485,0.00001513969,0.00008765272,0.0001628766,0.000001199968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008011069,"about_ca_system_score_gemma":0.0001515744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005902218,"about_ca_topic_score_gemma":0.0001870599,"domain_scores_codex":[0.9983699,0.0000342711,0.0002829363,0.0006562559,0.0002559542,0.0004006989],"domain_scores_gemma":[0.999269,0.00005443835,0.0001358732,0.0002476881,0.00007040016,0.0002225696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005825205,0.0001707611,0.0121292,0.000103644,0.0001893156,0.000009973318,0.0004004147,0.0003219302,0.9821633,1.388418e-7,0.0002605631,0.003668262],"study_design_scores_gemma":[0.001307437,0.0001833404,0.001274887,0.0005365809,0.0001219323,0.000005217191,0.0006685036,0.0008883014,0.9942344,0.000001879755,0.0004248267,0.0003526532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971781,0.001204295,0.0008372222,0.0003219309,0.0000383615,0.0001689549,0.00003530244,0.00001094753,0.0002049207],"genre_scores_gemma":[0.9957578,0.001722422,0.0007368884,0.0004366261,0.000768074,0.00006272995,0.00001137008,0.0000371258,0.0004670246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01207117,"threshold_uncertainty_score":0.9999761,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3199057479","doi":"10.2174/1871520621666210910101349","title":"Molecular and Metabolomic Investigation of Celecoxib Antiproliferative Activity inMono-and Combination Therapy against Breast Cancer Cell Models","year":2021,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Celecoxib; Propidium iodide; Pharmacology; Raloxifene; Cancer cell; Cancer research; Estrogen receptor; Cancer; Breast cancer; Apoptosis; MTT assay; Cell growth; Chemistry; Annexin; Programmed cell death; Medicine; Internal medicine; Biochemistry","authors":[{"name":"Sanaa K. Bardaweel","is_ca":false},{"name":"Lina A. Dahabiyeh","is_ca":false},{"name":"Bushra M. Akileh","is_ca":false},{"name":"Dana Shalabi","is_ca":false},{"name":"Afnan K. AlHiary","is_ca":false},{"name":"Judy Pawling","is_ca":true},{"name":"James W. Dennis","is_ca":true},{"name":"Anas M. Abdel Rahman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01954783460859409,"gpt":0.2824058576408613,"spread":0.2628580230322672,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002496023,0.0002115369,0.0004869044,0.00004109176,0.00004629407,0.00001002488,0.0000529819,0.0001549248,0.00006553869],"category_scores_gemma":[0.00002296682,0.0001920613,0.00004478492,0.0001858036,0.000186326,0.0001611115,0.0000394982,0.0002760832,2.27506e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001097383,"about_ca_system_score_gemma":0.0003241249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001986646,"about_ca_topic_score_gemma":0.00001056658,"domain_scores_codex":[0.9987395,0.00007941879,0.0002756237,0.0003642725,0.0003270874,0.000214145],"domain_scores_gemma":[0.9992841,0.00003799485,0.000176027,0.0001741453,0.0001763956,0.0001513662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001938222,0.0001104997,0.1136416,0.000723255,0.00008281663,0.00005913954,0.0006957268,0.00005986519,0.8789818,0.000007814017,0.00004183354,0.005401804],"study_design_scores_gemma":[0.003367042,0.00003256779,0.1442342,0.000354765,0.00007250861,0.00001794428,0.0001457098,0.004301315,0.8472769,0.00004703184,0.0000107392,0.000139308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935741,0.005234112,0.00003719025,0.0004051976,0.00009697884,0.000282164,0.0000285285,0.00001330725,0.0003284211],"genre_scores_gemma":[0.9881219,0.01108465,0.0000418822,0.0004944908,0.00009501401,0.00005896523,0.00002858478,0.00002211941,0.00005243921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03170493,"threshold_uncertainty_score":0.7832034,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044637095","doi":"10.2174/187152012799014995","title":"Bisphosphonate Anticancer Activity in Prostate Cancer and Other Genitourinary Cancers","year":2012,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Bone health and treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Novartis Pharmaceuticals Corporation","keywords":"Prostate cancer; Genitourinary system; Medicine; Oncology; Bisphosphonate; Cancer; Internal medicine; Prostate; Gynecology; Osteoporosis","authors":[{"name":"Fred Saad","is_ca":true},{"name":"Peter Mulders","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08289201756074344,"gpt":0.4138154665058993,"spread":0.3309234489451559,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003716221,0.0008551037,0.002642963,0.0002037659,0.00007875732,0.00001547839,0.0002053163,0.0005306373,0.00112141],"category_scores_gemma":[0.00002804244,0.0006886243,0.0002111474,0.0006933474,0.0003083816,0.0001176059,0.0001287466,0.001474711,0.00001650733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00218221,"about_ca_system_score_gemma":0.002114785,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02319954,"about_ca_topic_score_gemma":0.0008647213,"domain_scores_codex":[0.9962432,0.00007944612,0.0008699826,0.0009928697,0.0006223698,0.001192165],"domain_scores_gemma":[0.9982544,0.00007386704,0.0004981256,0.0005171676,0.00005328619,0.0006031625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002725205,0.00032113,0.1512873,0.0459745,0.0003651367,0.0005709569,0.000202783,0.000001236443,0.00002856456,3.433718e-7,0.0002286189,0.8007469],"study_design_scores_gemma":[0.005591665,0.0001020491,0.03333643,0.05418593,0.002284327,0.0002630075,0.00006372389,0.00002464607,0.0005377285,0.000003515754,0.902623,0.0009840041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1300703,0.8666295,2.075237e-7,0.000174121,0.0005029692,0.001342263,0.0002501626,0.00003448089,0.0009960741],"genre_scores_gemma":[0.05088513,0.9444242,0.0000271062,0.0005069281,0.0002819379,0.001197424,0.00005007283,0.0001382484,0.002489004],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9023944,"threshold_uncertainty_score":0.9997917,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3047874271","doi":"10.2174/1871520620666200807223832","title":"Therapeutic Applications of Curcumin and its Novel Formulations in the Treatment of Bladder Cancer: A Review of Current Evidence","year":2020,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Bladder cancer; Curcumin; Medicine; Cancer; Disease; Oncology; Internal medicine; Pharmacology","authors":[{"name":"Mohammad Hossein Pourhanifeh","is_ca":false},{"name":"Reza Mottaghi","is_ca":false},{"name":"Zahra Razavi","is_ca":false},{"name":"Alimohammad Shafiee","is_ca":true},{"name":"Sarah Hajighadimi","is_ca":true},{"name":"Hamed Mirzaei","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1336680552544256,"gpt":0.4526393122468229,"spread":0.3189712569923974,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002163724,0.0002889668,0.001032113,0.00004958256,0.00002230449,0.000002508077,0.0004786086,0.0001757061,0.00008070497],"category_scores_gemma":[0.0000686093,0.00020138,0.0002065833,0.0006457754,0.0002298288,0.00000447561,0.00006979636,0.0001858193,6.286783e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007311637,"about_ca_system_score_gemma":0.0005275997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005747257,"about_ca_topic_score_gemma":0.000008941522,"domain_scores_codex":[0.9980398,0.00005253781,0.0009622124,0.0004405268,0.0003274143,0.0001775279],"domain_scores_gemma":[0.9985755,0.0001065142,0.000666897,0.0004707006,0.0001113497,0.00006900645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009847294,0.0006440234,0.0002686148,0.0931628,0.0002239553,7.791728e-7,0.0001514717,0.000001052007,0.008772164,0.0000216295,0.0002258634,0.8965178],"study_design_scores_gemma":[0.0004229522,0.00008200016,0.0001388708,0.04243191,0.000866087,0.000007895251,0.00003158812,0.0000168432,0.006783854,0.000008532663,0.9490187,0.0001907261],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007295721,0.9968041,0.0002686394,0.0002618394,0.00002701497,0.001466467,0.0003983158,0.000002171135,0.00004193739],"genre_scores_gemma":[0.007681729,0.9899008,0.00002831069,0.00007747212,0.0001538251,0.001884101,0.0002289714,0.00001899994,0.00002574886],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9487929,"threshold_uncertainty_score":0.8212038,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3081134189","doi":"10.2174/1871520620666200819112632","title":"N-Terminal-Dependent Protein Degradation and Targeting Cancer Cells","year":2020,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Degron; Proteasome; Cell biology; Protein degradation; Cancer cell; Ubiquitin; Proteolysis; Autophagy; Neurodegeneration; Biology; Chemistry; Ubiquitin ligase; Cancer; Biochemistry; Apoptosis; Medicine","authors":[{"name":"Mohamed A. Eldeeb","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03278045372766937,"gpt":0.3397011886343044,"spread":0.306920734906635,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002419492,0.0005061405,0.0008826181,0.00005105217,0.00007734197,0.00003810472,0.0003584439,0.0004882184,0.0002441931],"category_scores_gemma":[0.00009855722,0.0004528521,0.0001603345,0.000192782,0.0001208302,0.000009836657,0.0002172855,0.0005420415,0.000007679465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001280578,"about_ca_system_score_gemma":0.0004275439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008715926,"about_ca_topic_score_gemma":0.000007937002,"domain_scores_codex":[0.9976236,0.00009267955,0.000684956,0.0008632332,0.0003672498,0.0003683048],"domain_scores_gemma":[0.9989941,0.00001004879,0.0004560298,0.0002881493,0.00006025679,0.0001914264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000389864,0.00008823006,0.0001628471,0.02027505,0.0002340798,0.0001292674,0.0000566274,0.000003859814,0.1683859,0.000001111117,0.006826073,0.803798],"study_design_scores_gemma":[0.0004385841,0.00003280977,0.000004609766,0.005355683,0.00016149,0.00001905902,0.00004249988,0.00001558003,0.2184351,0.000001489852,0.7750428,0.0004503031],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01306586,0.9853573,0.00003958368,0.0001026586,0.0002547677,0.0007675969,0.0001192447,0.00001817508,0.000274842],"genre_scores_gemma":[0.002397834,0.9931328,0.0001130624,0.0001543145,0.001119835,0.0004880244,0.0004762796,0.00006740796,0.002050413],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8033476,"threshold_uncertainty_score":0.9997923,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2937521850","doi":"10.2174/1871520619666190408132249","title":"Synthesis of 5-Alkynyltetrandrine Derivatives and Evaluation of their Anticancer Activity on A549 Cell Lines","year":2019,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"National Natural Science Foundation of China","keywords":"A549 cell; Chemistry; Cell culture; Pharmacology; Cell; Biology; Biochemistry; Genetics","authors":[{"name":"Nana Niu","is_ca":false},{"name":"Tingli Qu","is_ca":false},{"name":"Jinfang Xu","is_ca":false},{"name":"Xiaolin Lü","is_ca":false},{"name":"Graham J. Bodwell","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05726896788609508,"gpt":0.3780628580862254,"spread":0.3207938902001303,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005975871,0.000161645,0.0005170949,0.00008003514,0.00001667293,0.000002971587,0.0001050832,0.00009167426,0.001074835],"category_scores_gemma":[0.0001832104,0.0001224657,0.00005899597,0.0002554933,0.000200809,0.00005352027,0.00004763591,0.0002599613,0.000001974292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006401305,"about_ca_system_score_gemma":0.0001968745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001382081,"about_ca_topic_score_gemma":0.00000416097,"domain_scores_codex":[0.9984015,0.00005641063,0.0002829433,0.0002908892,0.0007632072,0.0002050165],"domain_scores_gemma":[0.9990779,0.0001937606,0.0001425716,0.0002832983,0.0002244744,0.00007797172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003877378,0.0003214099,0.194831,0.001799986,0.00007565165,0.000003677653,0.0002001351,0.00003253688,0.7726005,7.59614e-7,0.00006263689,0.02968401],"study_design_scores_gemma":[0.001810531,0.000106977,0.2399887,0.0008920338,0.00007284951,0.000002653618,0.0002170008,0.001164039,0.7555912,0.000007431653,0.00007015617,0.00007637064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917849,0.0007228351,0.000003089392,0.0002850619,0.00004821826,0.00032518,0.00001980988,0.000006100788,0.006804745],"genre_scores_gemma":[0.9975269,0.001895137,0.00003328822,0.00004655648,0.00009637764,0.00003104517,0.000005088347,0.0000161533,0.0003494012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04515776,"threshold_uncertainty_score":0.9998383,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3175385934","doi":"10.2174/1871520621666210623095636","title":"2-Methoxy-6-Acetyl-7-Methyljuglone: A Bioactive Phytochemical with Potential Pharmacological Activities","year":2021,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Bioactive natural compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Necroptosis; Phytochemical; Natural product; Pharmacology; Antimicrobial; Traditional medicine; Biology; Chemistry; Medicine; Apoptosis; Biochemistry; Programmed cell death; Microbiology","authors":[{"name":"Atif Ali Khan Khalil","is_ca":false},{"name":"Asma Saleem Qazi","is_ca":false},{"name":"Abdul Nasır","is_ca":false},{"name":"Mi‐Jeong Ahn","is_ca":false},{"name":"Muhammad Ajmal Shah","is_ca":false},{"name":"Muhammad Saad Ahmad","is_ca":false},{"name":"Wasim Sajjad","is_ca":false},{"name":"Tahir Ali","is_ca":true},{"name":"Muhammad Naeem","is_ca":false},{"name":"Fawad Ali Shah","is_ca":false},{"name":"Muhammad Tufail Ahmed Khan","is_ca":false},{"name":"Muhammad Romman","is_ca":false},{"name":"Shahfiq Ur Rehman","is_ca":false},{"name":"Adnan Haider","is_ca":false},{"name":"Raishma Noor","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04403389658146406,"gpt":0.3974581462821235,"spread":0.3534242497006594,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003329573,0.001047908,0.002198819,0.00009686658,0.0001112498,0.00005385166,0.0008194894,0.001396586,0.0005625613],"category_scores_gemma":[0.0001154274,0.0008193626,0.0006068703,0.0005926323,0.0007033633,0.00001544144,0.0005124721,0.002059496,0.000005150309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003702308,"about_ca_system_score_gemma":0.0009591402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002731225,"about_ca_topic_score_gemma":0.000003542939,"domain_scores_codex":[0.9957889,0.0003291957,0.0007004783,0.001628631,0.0007111939,0.0008415749],"domain_scores_gemma":[0.9983521,0.00008190113,0.0005299026,0.0005983078,0.0001632278,0.0002745463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007646659,0.001059497,0.0002173783,0.0132497,0.004996981,0.001238039,0.00007450393,0.00001736319,0.5699509,0.000002071451,0.009408557,0.3990203],"study_design_scores_gemma":[0.002085575,0.0002618037,0.0000320574,0.006347654,0.001796156,0.0005518951,0.0002501146,0.000008847759,0.3166842,0.000002720539,0.6704666,0.001512425],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03367991,0.9640007,0.0001051518,0.00006202287,0.0004140257,0.0006054222,0.0002109736,0.0000336032,0.0008881669],"genre_scores_gemma":[0.02169224,0.9733495,0.0004469131,0.0002337796,0.001799079,0.0004087132,0.0009568025,0.0001209059,0.0009920228],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.661058,"threshold_uncertainty_score":0.9998998,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2166963862","doi":"10.2174/187152012800228823","title":"Synthesis of Cis-Fused Pyran Indolocarbazole Derivatives that Inhibit FLT3 Kinase and the DNA Damage Kinase, Checkpoint Kinase 1","year":2012,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Lethbridge","funders":"Institut de Recherches Servier; Alberta Innovates","keywords":"Kinase; CHEK1; Pyran; Protein kinase A; Tyrosine kinase; G2-M DNA damage checkpoint; Cancer research; Biology; Chemistry; Biochemistry; Signal transduction; Cell cycle checkpoint; Cell; Cell cycle; Stereochemistry","authors":[{"name":"Françoise Perron‐Sierra","is_ca":false},{"name":"Nathalie Kucharkzyk","is_ca":false},{"name":"Céline Boucley","is_ca":false},{"name":"Christel Guyard-Daumas","is_ca":false},{"name":"Sophie Sciberras","is_ca":false},{"name":"Christine Fouache","is_ca":false},{"name":"Sabine Plantier","is_ca":false},{"name":"Aurélie Studény","is_ca":false},{"name":"Céline Bossard","is_ca":false},{"name":"Patrick Casara","is_ca":false},{"name":"Roy M. Golsteyn","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02924510103034042,"gpt":0.288381154162125,"spread":0.2591360531317846,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001034056,0.0004707329,0.0009795729,0.0001330472,0.0001112223,0.00001734239,0.0003089563,0.0003023091,0.0005446734],"category_scores_gemma":[0.0007438495,0.0003541626,0.0002001732,0.000521694,0.001266911,0.0001515137,0.0002176715,0.0008021418,0.000006271902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002512721,"about_ca_system_score_gemma":0.0002316784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003631763,"about_ca_topic_score_gemma":0.00001495909,"domain_scores_codex":[0.9970847,0.0001390348,0.0006991957,0.0005340914,0.0008332172,0.0007097815],"domain_scores_gemma":[0.9981049,0.000266116,0.0003960378,0.0007602139,0.0001104407,0.0003623024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001572839,0.0005534212,0.07104146,0.001688045,0.0004022075,0.0002187594,0.003199083,0.00001674375,0.9146084,0.00003129936,0.0008003333,0.005867468],"study_design_scores_gemma":[0.007219822,0.00005647517,0.05345281,0.001859955,0.0004237533,0.00005706395,0.001723317,0.0001632222,0.9339653,0.00002581057,0.0007337484,0.000318675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880309,0.006423434,0.00007224205,0.00114573,0.0002440822,0.0006385441,0.00004858788,0.00004843337,0.003348035],"genre_scores_gemma":[0.9967437,0.001685304,0.0001140861,0.0006114305,0.0003663924,0.0001912043,0.00003250899,0.00007172569,0.000183651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01935701,"threshold_uncertainty_score":0.999891,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2314229236","doi":"10.2174/187152012799014922","title":"Bisphosphonates in Lung Cancer: Can They Provide Benefits Beyond Prevention of Skeletal Morbidity?","year":2012,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Bone health and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Royal Victoria Hospital; Royal Victoria Regional Health Centre; McGill University Health Centre","funders":"Novartis Pharmaceuticals Corporation","keywords":"Zoledronic acid; Medicine; Breast cancer; Multiple myeloma; Context (archaeology); Oncology; Cancer; Lung cancer; Bone disease; Internal medicine; Osteoporosis","authors":[{"name":"Vera Hirsh","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06149832297355474,"gpt":0.3971120479484371,"spread":0.3356137249748824,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004333989,0.0006692724,0.00259231,0.0002038196,0.00004757271,0.000006960278,0.0002852046,0.0006170304,0.000634169],"category_scores_gemma":[0.00006687274,0.000542801,0.0003595781,0.0005372961,0.0001287552,0.00008922472,0.0001005313,0.001040755,0.000004883835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001173855,"about_ca_system_score_gemma":0.001932643,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01203837,"about_ca_topic_score_gemma":0.001750372,"domain_scores_codex":[0.9962505,0.00008011396,0.001393922,0.0007004389,0.00074029,0.0008347243],"domain_scores_gemma":[0.9980956,0.0000749625,0.0008294879,0.0005168527,0.00009675876,0.0003863043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007022749,0.0007454214,0.09906707,0.109239,0.0004688214,0.0001179017,0.0002237963,0.000003531061,0.00002849125,0.000002395032,0.0003125097,0.7897209],"study_design_scores_gemma":[0.01819259,0.0005055377,0.07938877,0.403375,0.01588885,0.0003966474,0.0002620272,0.0001125033,0.00626248,0.00006694015,0.4728355,0.002713147],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08310145,0.9138352,3.370663e-7,0.0001230083,0.0004617929,0.001543567,0.0002544167,0.00002359218,0.0006566647],"genre_scores_gemma":[0.07560542,0.9210906,0.00003423528,0.00009602791,0.0002897806,0.0007999297,0.0005250085,0.00008528176,0.001473743],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7870077,"threshold_uncertainty_score":0.9997023,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101474419","doi":"10.2174/1871520614666140309223603","title":"A Fluorescent Alkyllysophospholipid Analog Exhibits Selective Cytotoxicity Against the Hormone-Insensitive Prostate Cancer Cell Line PC3","year":2014,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Organophosphorus compounds synthesis","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"DU145; Cytotoxicity; Cell culture; Endoplasmic reticulum; Chemistry; Apoptosis; Cytotoxic T cell; Cancer cell; Cell; Biochemistry; LNCaP; Biology; Cancer; In vitro","authors":[{"name":"Pranati Samadder","is_ca":false},{"name":"Hoe‐Sup Byun","is_ca":false},{"name":"Robert Bittman","is_ca":false},{"name":"Gilbert Arthur","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01290657639469809,"gpt":0.2570500157000278,"spread":0.2441434393053298,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006014523,0.0008000787,0.0009126048,0.00005032529,0.0003507352,0.00007432146,0.0009248161,0.0003994883,0.000993947],"category_scores_gemma":[0.0002659464,0.0006500513,0.0002332936,0.0006300316,0.0005036012,0.0001610886,0.0003216537,0.001270765,0.00003236313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001377387,"about_ca_system_score_gemma":0.0004417726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002055115,"about_ca_topic_score_gemma":0.0001835842,"domain_scores_codex":[0.9954572,0.0001054272,0.0008862057,0.001247833,0.00111307,0.001190231],"domain_scores_gemma":[0.9975232,0.000285712,0.0005444179,0.0009764876,0.0003139863,0.0003561983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004019735,0.0004153057,0.02763974,0.0004478484,0.0002124823,0.00009818836,0.001595827,0.0003887382,0.9599237,0.000001695235,0.00424833,0.004626174],"study_design_scores_gemma":[0.00220453,0.0000423323,0.009358541,0.0005721761,0.0001528093,0.00001410653,0.0008286928,0.002176261,0.9818176,0.00002886863,0.002086744,0.0007173176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813613,0.003871902,0.00001781541,0.0007444722,0.0002511806,0.0003484922,0.0002003231,0.0001432047,0.01306134],"genre_scores_gemma":[0.989006,0.006506969,0.00007145086,0.001294079,0.00111418,0.0002778943,0.00006661376,0.0001303039,0.001532525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02189392,"threshold_uncertainty_score":0.9999193,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2235461151","doi":"10.2174/1871520615666150616123345","title":"Lgr5 Contributes to Intestinal Metaplasia During Gastric Carcinogenesis: A Meta analysis","year":2016,"lang":"en","type":"review","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"Internal medicine; Carcinogenesis; Intestinal metaplasia; Meta-analysis; LGR5; Medicine; Gastroenterology; Cancer; Metastasis; Oncology; Pathological; Cancer stem cell","authors":[{"name":"Ye Han","is_ca":false},{"name":"Qiaoming Zhi","is_ca":false},{"name":"Xiaofeng Xue","is_ca":false},{"name":"Bin Yuan","is_ca":false},{"name":"Hong Zhao","is_ca":false},{"name":"Yuting Kuang","is_ca":false},{"name":"Lifeng Zhang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.107982282790443,"gpt":0.3972828327653144,"spread":0.2893005499748714,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006804888,0.001130031,0.007867454,0.001028667,0.0001006332,0.00004039957,0.0006549844,0.0004374961,0.004926504],"category_scores_gemma":[0.0003035916,0.0007680545,0.003080144,0.003775951,0.0001816806,0.00006322054,0.0002882144,0.0008655257,0.00007304257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001105618,"about_ca_system_score_gemma":0.0010111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003466136,"about_ca_topic_score_gemma":0.0000398414,"domain_scores_codex":[0.9946063,0.0001360167,0.001647556,0.001528954,0.0009936575,0.001087524],"domain_scores_gemma":[0.9970388,0.0001986829,0.0006597218,0.001157402,0.0002567594,0.0006886339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005011338,0.0006986542,0.007358276,0.1109782,0.368193,0.002880177,0.0001378678,0.00002561686,0.003859674,0.000004123208,0.004121557,0.5012417],"study_design_scores_gemma":[0.001865594,0.00005977763,0.0008647869,0.014113,0.4810501,0.0003028748,0.00005791466,0.000002327645,0.005204801,0.000002324442,0.4956781,0.0007983799],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00296336,0.9940299,0.0001481154,0.0003036108,0.0002491448,0.001080298,0.0004388285,0.000065539,0.0007211476],"genre_scores_gemma":[0.004395285,0.9897709,0.0002099489,0.0003077844,0.0006876695,0.0009970933,0.0001816122,0.0001218628,0.003327824],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5004433,"threshold_uncertainty_score":0.999477,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3186339165","doi":"10.2174/1871520621666210726130028","title":"Gold Nanorods are Selective Cytotoxic Agents","year":2021,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Gold and Silver Nanoparticles Synthesis and Applications","field":"Materials Science","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Cytotoxic T cell; HeLa; Cytotoxicity; Cell culture; Cancer cell; Chemistry; Cancer research; Molecular biology; Cancer; Cell; Biology; In vitro; Medicine; Biochemistry; Internal medicine","authors":[{"name":"Mohamed A.M. El Gendy","is_ca":false},{"name":"Michael Weinfeld","is_ca":true},{"name":"Ahmed Sabry S. Abdoon","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03250431189965566,"gpt":0.3087838866188912,"spread":0.2762795747192355,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002040286,0.0001756169,0.0002945104,0.00001984737,0.00009881239,0.00004151543,0.0002789321,0.00009559328,0.002956461],"category_scores_gemma":[0.00007744291,0.0001616276,0.00006696134,0.0003438404,0.0001044206,0.000085423,0.00008805926,0.0001674834,0.00008618274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001236883,"about_ca_system_score_gemma":0.0001379372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008093996,"about_ca_topic_score_gemma":0.00002425773,"domain_scores_codex":[0.9983839,0.00004334921,0.0003207678,0.0004949362,0.0003624667,0.0003945642],"domain_scores_gemma":[0.9992754,0.00003885672,0.0001293451,0.0003262198,0.00009520536,0.000134898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009262098,0.0001710888,0.030058,0.00006957664,0.00001191894,0.00006153406,0.0001556973,0.00005113195,0.964368,0.00001011561,0.004448097,0.0005855915],"study_design_scores_gemma":[0.000457502,0.000006101077,0.04375354,0.0001872146,0.00002561209,0.00001179275,0.0004060527,0.00009786788,0.9519951,0.00005078583,0.002832523,0.0001759527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995868,0.000452604,0.00001011292,0.0005592656,0.0001690587,0.00009433634,0.00003976516,0.00003891082,0.002767936],"genre_scores_gemma":[0.9965976,0.0003184258,0.00008539227,0.0006048502,0.0002286221,0.00009187467,0.00001052953,0.00001652129,0.002046216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01369555,"threshold_uncertainty_score":0.997955,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4233585088","doi":"10.2174/187152061606160415122235","title":"Meet Our Editorial Board Member:","year":2016,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Lethbridge","funders":"","keywords":"Editorial board; Political science; Computer science; Library science","authors":[{"name":"Roy M. Golsteyn","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02042955069966068,"gpt":0.3366851200977534,"spread":0.3162555693980927,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002042617,0.0002268027,0.0002233995,0.00002963091,0.00005556771,0.00001375816,0.0003611612,0.0002893429,0.0004803532],"category_scores_gemma":[0.0002612197,0.0001752348,0.00009834676,0.000097322,0.00008432641,0.00001019291,0.0001413302,0.0001848775,0.00003343736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009901042,"about_ca_system_score_gemma":0.000154812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001026492,"about_ca_topic_score_gemma":0.00003567678,"domain_scores_codex":[0.9983701,0.00003484416,0.0003146969,0.0005076858,0.0003868924,0.0003858505],"domain_scores_gemma":[0.9991869,0.00001361914,0.000122101,0.0004223859,0.0001125251,0.0001424602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008855239,0.00005300049,0.00835418,0.00003379709,0.00005492566,0.00001070844,0.00001706032,0.000005395342,0.7297441,0.000001628881,0.2607328,0.0009038826],"study_design_scores_gemma":[0.001262784,0.00004315471,0.000874134,0.0001659712,0.00002125381,0.00001053895,0.00009265709,0.000003049407,0.7343805,0.00001946711,0.2629166,0.0002098485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790003,0.0004072794,0.0001806237,0.001708146,0.01288349,0.0001824457,0.00006227876,0.00002838942,0.005547063],"genre_scores_gemma":[0.963381,0.0004898952,0.00008781114,0.0002182719,0.02927394,0.0001112977,0.00002356387,0.00003375215,0.006380491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01639044,"threshold_uncertainty_score":0.714587,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}