{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":124,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":124,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"53e2dbca3f80","filters":{"venue":"Cancer Biology & Therapy"}},"results":[{"id":"W2120191503","doi":"10.4161/cbt.213","title":"Human Tumor Xenografts as Predictive Preclinical Models for Anticancer Drug Activity in Humans: Better than Commonly Perceived—But They Can Be Improved","year":2003,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":325,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Sunnybrook Health Science Centre","funders":"National Cancer Institute; St. Jude Children's Research Hospital","keywords":"Medicine; In vivo; Cancer; Drug; Transplantation; Cancer research; Efficacy; Pharmacology; Oncology; Immunology; Internal medicine; Biology","authors":[{"name":"Robert S. Kerbel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04482851762084782,"gpt":0.3753929126132779,"spread":0.3305643949924301,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002996095,0.0003534899,0.0004394359,0.00007676909,0.0002107094,0.00002885314,0.000338726,0.0002405008,0.00005939529],"category_scores_gemma":[0.00002760388,0.0002949284,0.0002285378,0.00007855953,0.0003612382,0.0000147733,0.00006420104,0.0002725336,0.000001287609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000156336,"about_ca_system_score_gemma":0.0004316006,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005282833,"about_ca_topic_score_gemma":0.02087572,"domain_scores_codex":[0.9976777,0.0003365815,0.0002924606,0.0008633402,0.0001089769,0.0007209395],"domain_scores_gemma":[0.9989978,0.00005416731,0.0001329804,0.0005345052,0.0001101063,0.0001704237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00376769,0.0008695397,0.1431699,0.00003100436,0.0009997699,0.000009746539,0.0008271035,0.00007671148,0.8400716,0.0003023173,0.0009641986,0.008910434],"study_design_scores_gemma":[0.0381597,0.01681182,0.1808072,0.0001835399,0.0001964292,0.00002328987,0.0005601697,0.0004862613,0.6652364,0.02522787,0.06980431,0.002503106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937285,0.002565491,0.0000753575,0.0009805306,0.0002176608,0.001396383,0.000701432,0.00002303547,0.0003115655],"genre_scores_gemma":[0.9924612,0.00326242,0.0001019751,0.001683333,0.000316951,0.001651339,0.0001938884,0.00005547576,0.0002734058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1748352,"threshold_uncertainty_score":0.9999503,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1982047458","doi":"10.4161/cbt.26726","title":"AMP-activated protein kinase (AMPK) beyond metabolism","year":2013,"lang":"en","type":"review","venue":"Cancer Biology & Therapy","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":213,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"","keywords":"AMPK; Protein kinase A; Cancer research; PI3K/AKT/mTOR pathway; Cell biology; Biology; Cancer cell; Kinase; DNA damage; DNA repair; Signal transduction; Cancer; Biochemistry; Genetics","authors":[{"name":"Toran Sanli","is_ca":true},{"name":"Gregory R. Steinberg","is_ca":true},{"name":"Gurmit Singh","is_ca":true},{"name":"Theodoros Tsakiridis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05101509368095881,"gpt":0.3508950488333401,"spread":0.2998799551523813,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002579846,0.00099567,0.002130268,0.0001594715,0.0001415701,0.00005298778,0.0008693243,0.001456945,0.001467275],"category_scores_gemma":[0.00003476634,0.0007365646,0.0007961998,0.0003120551,0.0003731482,0.000008885291,0.0001558548,0.000523114,0.0001636429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006918499,"about_ca_system_score_gemma":0.000749744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001582168,"about_ca_topic_score_gemma":0.00003122256,"domain_scores_codex":[0.9964211,0.000577893,0.0007195015,0.001282602,0.0001407313,0.0008581756],"domain_scores_gemma":[0.997701,0.00002349968,0.0006219196,0.0012032,0.0002112318,0.0002390822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000418196,0.00005937709,0.000002773121,0.0005134611,0.0009112431,9.307799e-7,0.00002044298,2.0611e-7,0.03420955,0.0001187341,0.005123435,0.958998],"study_design_scores_gemma":[0.0007165796,0.0001168142,0.000002576159,0.0004505606,0.0002397515,0.000004166081,0.000003899439,7.163279e-8,0.01646548,0.0001837418,0.9809711,0.0008452379],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003727077,0.9917123,0.00003267388,0.00002359134,0.00147356,0.002141975,0.0005428228,0.00005370659,0.000292236],"genre_scores_gemma":[0.00002893029,0.9874201,0.0002189923,0.0009757595,0.002750075,0.004678552,0.001876737,0.0001869679,0.001863903],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9758477,"threshold_uncertainty_score":0.9998394,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2001823769","doi":"10.4161/cbt.3.2.663","title":"Neosis: A Novel Type of Cell Division in Cancer","year":2004,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":209,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"Dalhousie University","keywords":"Mitosis; Biology; Cytokinesis; Carcinogenesis; Cancer cell; Multinucleate; Mitotic catastrophe; Cell division; Cell biology; Cell; Cancer research; Cell culture; Cancer; Genetics","authors":[{"name":"Meenakshi Sundaram","is_ca":true},{"name":"Duane L. Guernsey","is_ca":false},{"name":"Murali Rajaraman","is_ca":false},{"name":"Rengaswami Rajaraman","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02259495608932507,"gpt":0.3120471214325378,"spread":0.2894521653432127,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006377175,0.0001282714,0.0001717265,0.00004181451,0.00002159985,0.00000285358,0.0001743582,0.0002063187,0.00004326705],"category_scores_gemma":[0.000004345814,0.0001094376,0.00005978931,0.0001076393,0.00008345822,0.000001999796,0.00004196202,0.00007819848,0.000002362358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003390271,"about_ca_system_score_gemma":0.0001828503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008108614,"about_ca_topic_score_gemma":0.0004737086,"domain_scores_codex":[0.9992969,0.00002058471,0.0001738961,0.0002738539,0.00003192685,0.0002028274],"domain_scores_gemma":[0.999602,0.00000416592,0.00008160288,0.0002160899,0.00006383187,0.00003234201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001313405,0.0001291516,0.02063342,0.000007703718,0.00003303779,2.694151e-7,0.00009360911,0.0003600778,0.9738274,0.00005130704,0.00007207508,0.004660588],"study_design_scores_gemma":[0.002223568,0.0004766735,0.0109578,0.00003680103,0.000006934814,9.300812e-7,0.00002928041,0.000008930054,0.9629997,0.0001259083,0.02295496,0.0001784893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813138,0.01723282,0.0006720743,0.00017272,0.0002899698,0.0001568461,0.00005090947,0.000005283627,0.0001055246],"genre_scores_gemma":[0.9712824,0.02730867,0.0003057076,0.0007793285,0.0001090726,0.00005209771,0.00005146338,0.000017056,0.00009426262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02288289,"threshold_uncertainty_score":0.4462737,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2084102070","doi":"10.4161/cbt.7.7.6208","title":"Genome-wide profiling at methylated promoters in pancreatic adenocarcinoma","year":2008,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; Sidney Kimmel Center for Prostate and Urologic Cancers; University of Toronto; Johns Hopkins University; Sidney Kimmel Comprehensive Cancer Center; University of Nebraska Medical Center","keywords":"Promoter; Genome; Profiling (computer programming); Biology; Computational biology; Genetics; Gene expression profiling; Cancer research; Gene; Gene expression; Computer science","authors":[{"name":"Noriyuki Omura","is_ca":false},{"name":"Chung‐Pin Li","is_ca":false},{"name":"Ang Li","is_ca":false},{"name":"Seung‐Mo Hong","is_ca":false},{"name":"Kimberly Walter","is_ca":false},{"name":"Antonio Jimeno","is_ca":false},{"name":"Manuel Hidalgo","is_ca":false},{"name":"Michael Goggins","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02990986792227522,"gpt":0.2863467269696899,"spread":0.2564368590474146,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001850723,0.000197256,0.000235294,0.0000779122,0.0001050944,0.000004734794,0.0001752372,0.0002586212,0.00005786355],"category_scores_gemma":[0.00002947764,0.0001746793,0.00007904471,0.0001469157,0.0001542471,0.000002904504,0.00005668614,0.0001065116,0.000008494826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007135524,"about_ca_system_score_gemma":0.0001231042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000823174,"about_ca_topic_score_gemma":0.00006686195,"domain_scores_codex":[0.9986997,0.0001585208,0.0002681918,0.000472881,0.0000591417,0.000341538],"domain_scores_gemma":[0.9994313,0.0000229842,0.0001035339,0.0003116742,0.00006130942,0.00006918641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001079334,0.00001879918,0.4419033,0.000003154751,0.00003973925,0.000003170123,0.0001069728,0.00005672897,0.5570711,0.000003191048,0.000006117649,0.0006797106],"study_design_scores_gemma":[0.0008992784,0.0003227574,0.3847435,0.000005687999,0.000006365766,0.000003961694,0.00001293172,0.00002230571,0.6072177,0.000138557,0.006426427,0.0002005521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.948719,0.05011734,0.0002596269,0.0001478367,0.0001495699,0.0003910707,0.00001530662,0.00001592492,0.000184375],"genre_scores_gemma":[0.9777902,0.020569,0.0004757804,0.0002974397,0.0001583793,0.0001391312,0.0002383436,0.00003103729,0.0003006454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05715986,"threshold_uncertainty_score":0.7123216,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2041002214","doi":"10.4161/cbt.6.1.3489","title":"Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression","year":2007,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":164,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"TMPRSS2; Prostate cancer; Fusion gene; Medicine; Prostate; Erg; Oncology; PCA3; Hazard ratio; Internal medicine; Cancer; Fusion protein; Clinical significance; Cancer research; Disease; Gene; Biology; Confidence interval; Genetics; Ophthalmology","authors":[{"name":"Robert K. Nam","is_ca":true},{"name":"Linda Sugar","is_ca":false},{"name":"Zhenghui Wang","is_ca":false},{"name":"Wenyi Yang","is_ca":false},{"name":"A. Richard Kitching","is_ca":false},{"name":"Laurence Klotz","is_ca":false},{"name":"Vasundara Venkateswaran","is_ca":false},{"name":"Steven A. Narod","is_ca":false},{"name":"Arun Seth","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05431220669703656,"gpt":0.4132996575416807,"spread":0.3589874508446441,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003738105,0.000336543,0.0006033398,0.0002502043,0.0001085187,0.00000987011,0.0001799332,0.0002735645,0.0005926308],"category_scores_gemma":[0.00001145069,0.0002150436,0.0001310582,0.0003216375,0.0002405386,0.0001022843,0.00004433304,0.0002511335,0.000001140082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003894049,"about_ca_system_score_gemma":0.0007598769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007809493,"about_ca_topic_score_gemma":0.0004664563,"domain_scores_codex":[0.9976127,0.00006992234,0.000613976,0.000674819,0.0002452117,0.0007834423],"domain_scores_gemma":[0.9986845,0.00008732226,0.0003196847,0.0003457323,0.0003200981,0.0002426804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004541596,0.0002734769,0.3202064,0.0001009852,0.00006146316,0.00001331804,0.001434765,0.000003078768,0.5653878,0.000001882155,0.0001243079,0.1078509],"study_design_scores_gemma":[0.00595574,0.001854832,0.09787066,0.0005514859,0.00003482168,0.000002262508,0.0001387171,0.00007283252,0.8852662,0.00006989406,0.007950322,0.0002321724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9471292,0.04730523,0.0000430699,0.0007816372,0.0005418689,0.003409025,0.0007268866,0.00004641003,0.00001663628],"genre_scores_gemma":[0.9294107,0.06682148,0.0005914946,0.0003982666,0.0003065295,0.001906659,0.0001520012,0.00006222203,0.0003506649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3198784,"threshold_uncertainty_score":0.8769222,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2094049846","doi":"10.4161/cbt.22020","title":"The human proton-coupled folate transporter","year":2012,"lang":"en","type":"review","venue":"Cancer Biology & Therapy","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":151,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Transporter; Pemetrexed; Gene; Cytotoxic T cell; Antifolate; Purine; Nucleotide; Cancer research; Biochemistry; Genetics; Cancer; In vitro; Antimetabolite; Enzyme; Chemotherapy","authors":[{"name":"Sita Kugel Desmoulin","is_ca":false},{"name":"Zhanjun Hou","is_ca":false},{"name":"Aleem Gangjee","is_ca":false},{"name":"Larry H. Matherly","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1693784864947777,"gpt":0.4661066865408479,"spread":0.2967282000460702,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005100935,0.0004323241,0.001416792,0.0001153192,0.0002765967,0.00002007145,0.0004061277,0.0006272499,0.0009520299],"category_scores_gemma":[0.000003813505,0.0002026639,0.0006156195,0.0002360358,0.0003719596,0.0000312049,0.00002457472,0.0008600633,0.0001334308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001377564,"about_ca_system_score_gemma":0.0004433804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001047991,"about_ca_topic_score_gemma":0.00003905445,"domain_scores_codex":[0.9979974,0.0001870271,0.0005097421,0.000426623,0.0001470328,0.0007321561],"domain_scores_gemma":[0.9987623,0.0001024586,0.000185323,0.0006911178,0.0000948035,0.0001639829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006946719,0.00006189303,0.0003715775,0.001627257,0.001049101,0.000009390308,0.00006789796,2.012414e-9,0.0002075448,0.00007262579,0.0002588762,0.9962044],"study_design_scores_gemma":[0.0007724666,0.0003775088,0.0001315996,0.001215563,0.0004382991,0.00002794555,0.000003758078,3.792615e-7,0.00002712307,0.00004334869,0.996738,0.0002240672],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001128435,0.9939095,0.000002980837,0.0002833634,0.0003969173,0.003781351,0.00003648563,0.00005381037,0.0004071903],"genre_scores_gemma":[0.0002460447,0.9905508,0.00000513339,0.0002509199,0.001165711,0.003121021,0.0002353914,0.00008638443,0.004338608],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9964791,"threshold_uncertainty_score":0.9999613,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2068605060","doi":"10.4161/cbt.8.9.8210","title":"PIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"DOD Prostate Cancer Research Program; University of Lethbridge; U.S. Department of Defense","keywords":"PIM1; PI3K/AKT/mTOR pathway; Phosphorylation; Protein kinase B; Wortmannin; Cell biology; Kinase; Protein phosphorylation; Protein kinase A; RPTOR; Biology; Autophagy-related protein 13; Cancer research; Chemistry; Signal transduction; Serine","authors":[{"name":"Fengxue Zhang","is_ca":false},{"name":"Zanna Beharry","is_ca":false},{"name":"Thurl E. Harris","is_ca":false},{"name":"Michael B. Lilly","is_ca":false},{"name":"Charles D. Smith","is_ca":false},{"name":"Sandeep Mahajan","is_ca":false},{"name":"Andrew S. Kraft","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01742005913855463,"gpt":0.2955231851807296,"spread":0.278103126042175,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001644537,0.0001795854,0.0003222002,0.00008558633,0.00005155542,0.00001047867,0.00005740645,0.0001869274,0.0002764838],"category_scores_gemma":[0.000004387006,0.0001441987,0.00005022594,0.0001636096,0.00007997751,0.00006248101,0.000007874251,0.0001806994,0.000003094076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000127734,"about_ca_system_score_gemma":0.0001052394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002975619,"about_ca_topic_score_gemma":0.00006725888,"domain_scores_codex":[0.9990965,0.00005878846,0.000158875,0.0003588733,0.00006557263,0.0002613549],"domain_scores_gemma":[0.9995482,0.00001929442,0.00008941878,0.0002190924,0.00004284481,0.00008115521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001222934,0.00009512127,0.001294254,0.000006508588,0.00002428655,0.000004646502,0.0002166957,0.000001641152,0.7357501,0.0003706846,0.00005886519,0.2609542],"study_design_scores_gemma":[0.003849735,0.001484217,0.06323922,0.00008571647,0.00001021288,0.000004017875,0.00002426826,0.00007823425,0.9132639,0.004023932,0.01374351,0.0001930521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863101,0.00920395,0.0001124609,0.003134622,0.0001791206,0.0008790503,0.00001206486,0.00004961877,0.000119038],"genre_scores_gemma":[0.9925193,0.004870193,0.0002910929,0.00165316,0.0002142427,0.0001169828,0.000008609125,0.00001695286,0.0003094927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2607612,"threshold_uncertainty_score":0.5880253,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2107723175","doi":"10.4161/cbt.8.21.9685","title":"A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; University of Toronto; University of Nebraska Medical Center","keywords":"microRNA; Biology; Cancer research; Gene expression profiling; Cell culture; Cell growth; Regulation of gene expression; Gene expression; Epithelial–mesenchymal transition; Cell biology; Downregulation and upregulation; Gene; Genetics","authors":[{"name":"Oliver A. Kent","is_ca":false},{"name":"Michael E. Mullendore","is_ca":false},{"name":"Eric A. Wentzel","is_ca":false},{"name":"Pedro López‐Romero","is_ca":false},{"name":"Aik Choon Tan","is_ca":false},{"name":"Alvarez Hector","is_ca":false},{"name":"Kristen M. West","is_ca":false},{"name":"Michael F. Ochs","is_ca":false},{"name":"Manuel Hidalgo","is_ca":false},{"name":"Dan E. Arking","is_ca":false},{"name":"Anirban Maitra","is_ca":false},{"name":"Joshua T. Mendell","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01381947601842095,"gpt":0.2741983881558747,"spread":0.2603789121374537,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000890406,0.0001004556,0.0001945075,0.0001125143,0.00002570553,0.000003635613,0.00006688355,0.0001411892,0.00001448664],"category_scores_gemma":[0.000006477686,0.00008838059,0.00008579841,0.0001508698,0.00006133789,0.000002344923,0.00001171324,0.00002940465,1.141928e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001512887,"about_ca_system_score_gemma":0.00002764319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001618642,"about_ca_topic_score_gemma":0.00001402788,"domain_scores_codex":[0.9993357,0.0000599583,0.0001685419,0.0002798196,0.00002505138,0.000130896],"domain_scores_gemma":[0.9996359,0.00001331674,0.0001030098,0.0001800525,0.00003699135,0.00003071745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007728833,0.00003244142,0.06011189,0.000005622703,0.000175357,1.600167e-7,0.0000558383,0.000080777,0.9355471,0.0000123571,0.0001510663,0.00305452],"study_design_scores_gemma":[0.0009417636,0.0003774219,0.3775496,0.00001127957,0.0001318713,6.415411e-7,0.00002670746,0.00009370063,0.6173695,0.0001179569,0.003280805,0.00009869499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803878,0.01828284,0.0009043764,0.0000892746,0.00003527424,0.0002349696,0.00004940641,0.00000419299,0.00001185428],"genre_scores_gemma":[0.9981027,0.001060173,0.0002345647,0.0002428073,0.00007871295,0.00003773321,0.0002068856,0.0000073256,0.00002913981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3181776,"threshold_uncertainty_score":0.3604056,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2025899661","doi":"10.4161/cbt.10.8.13083","title":"MicroRNA<i>miR-17-5p</i>is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion","year":2010,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"Pancreatic cancer; Pancreatic Intraepithelial Neoplasia; Oncogene; Cancer research; Ductal cells; microRNA; Carcinogenesis; Cancer; Biology; Downregulation and upregulation; Cell growth; Pancreas; Transfection; Cancer cell; Adenocarcinoma; Pathology; Cell culture; Medicine; Internal medicine; Cell cycle; Endocrinology; Pancreatic ductal adenocarcinoma; Gene","authors":[{"name":"Jun Yu","is_ca":false},{"name":"Kenoki Ohuchida","is_ca":false},{"name":"Kazuhiro Mizumoto","is_ca":false},{"name":"Hayato Fujita","is_ca":false},{"name":"Kouhei Nakata","is_ca":true},{"name":"Masao Tanaka","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01365236586981949,"gpt":0.2633774502451428,"spread":0.2497250843753233,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001560135,0.0002375459,0.0002644736,0.00006456803,0.00005797459,0.00002522638,0.0001046794,0.0003524537,0.00006394309],"category_scores_gemma":[0.00001736731,0.0001983515,0.0000269917,0.0001393107,0.0001751166,0.00001619593,0.00004119825,0.0001708505,1.953896e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007945085,"about_ca_system_score_gemma":0.0002682797,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002213704,"about_ca_topic_score_gemma":0.03108293,"domain_scores_codex":[0.9987435,0.0001150422,0.0002401606,0.00054555,0.00006368742,0.0002920657],"domain_scores_gemma":[0.9994619,0.00002119043,0.0001742449,0.000172847,0.00009292983,0.00007691368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002659883,0.00007082978,0.4199751,0.00001668419,0.00003821173,3.994054e-7,0.0001477287,0.000005151887,0.5782588,0.000002012462,0.0002084251,0.00101066],"study_design_scores_gemma":[0.003362576,0.0002374579,0.3243745,0.0001348957,0.00002399303,0.000001268392,0.00003623953,0.0001135606,0.6690876,0.00005558115,0.002290982,0.0002813452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789428,0.01948893,0.00000727591,0.0004989054,0.00008254957,0.0008334392,0.0001178583,0.0000120387,0.00001627271],"genre_scores_gemma":[0.9827365,0.01489351,0.00009526989,0.001023632,0.0001092658,0.0008733309,0.0001781137,0.00003037468,0.0000600314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09560063,"threshold_uncertainty_score":0.9865973,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2768342523","doi":"10.1080/15384047.2017.1394542","title":"Main components of pomegranate, ellagic acid and luteolin, inhibit metastasis of ovarian cancer by down-regulating MMP2 and MMP9","year":2017,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Pomegranate: compositions and health benefits","field":"Nursing","cited_by":102,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Ellagic acid; Ovarian cancer; MMP9; MMP2; Luteolin; Cancer research; Cancer; Cell growth; Metastasis; Chemistry; Pharmacology; Biology; Medicine; Internal medicine; Antioxidant; Downregulation and upregulation; Flavonoid; Biochemistry","authors":[{"name":"Huidi Liu","is_ca":true},{"name":"Zheng Zeng","is_ca":false},{"name":"Siwen Wang","is_ca":false},{"name":"Ting Li","is_ca":false},{"name":"Emilio Mastriani","is_ca":false},{"name":"Qinghai Li","is_ca":false},{"name":"Hongxia Bao","is_ca":false},{"name":"Yujie Zhou","is_ca":false},{"name":"Xiaoyu Wang","is_ca":false},{"name":"Yongfang Liu","is_ca":false},{"name":"Wei Liu","is_ca":false},{"name":"Sijing Hu","is_ca":false},{"name":"Shan Gao","is_ca":false},{"name":"Miao Yu","is_ca":false},{"name":"Yingying Qi","is_ca":false},{"name":"Zhihang Shen","is_ca":false},{"name":"Hongyue Wang","is_ca":false},{"name":"Tingting Gao","is_ca":false},{"name":"Lingqin Dong","is_ca":false},{"name":"Randal N. Johnston","is_ca":true},{"name":"Shu‐Lin Liu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03993947044782489,"gpt":0.3401834070830722,"spread":0.3002439366352473,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002835265,0.0002308262,0.0006000528,0.000135891,0.0005074764,0.00002665247,0.0002299541,0.000186395,0.00007818839],"category_scores_gemma":[0.000007549495,0.0001946548,0.00006610722,0.00009686978,0.0005717214,0.0001079635,0.00006132952,0.0001653766,4.981056e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006040228,"about_ca_system_score_gemma":0.00003967205,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01320122,"about_ca_topic_score_gemma":0.001061311,"domain_scores_codex":[0.9985833,0.0001307215,0.0004406679,0.0003778418,0.0000931383,0.0003743698],"domain_scores_gemma":[0.9988033,0.0000626805,0.0005170716,0.0003843169,0.0001116545,0.0001209804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008444833,0.00008219117,0.05382759,0.0001139964,0.000240223,8.027748e-7,0.0007738948,0.000008610329,0.7888634,0.0004306017,0.0005117066,0.1543025],"study_design_scores_gemma":[0.01400931,0.001261472,0.5034159,0.0009330167,0.0002765358,0.00002742789,0.0002342963,0.0007520627,0.4476593,0.005984392,0.0244416,0.001004639],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.950192,0.04448753,0.00002983227,0.003588814,0.0004125705,0.0003268723,0.0008479503,0.0000178305,0.00009663988],"genre_scores_gemma":[0.9852822,0.0134699,0.0004620925,0.0005697532,0.00008119841,0.00004315011,0.00004024102,0.00002489654,0.00002657105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4495883,"threshold_uncertainty_score":0.9933699,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1985031257","doi":"10.4161/cbt.6.5.4007","title":"Drug-induced inactivation or gene silencing of class I histone deacetylases suppresses ovarian cancer cell growth: Implications for therapy","year":2007,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Women's Health Research Institute","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources","keywords":"Ovarian cancer; Romidepsin; HDAC3; Histone deacetylase; Cancer research; Biology; Gene silencing; Vorinostat; Cell growth; Small interfering RNA; Cancer; Histone; Cell culture; Gene; Genetics; Transfection","authors":[{"name":"Dineo Khabele","is_ca":false},{"name":"Deok-Soo Son","is_ca":false},{"name":"Angelika K. Parl","is_ca":false},{"name":"Gary L. Goldberg","is_ca":true},{"name":"Leonard H. Augenlicht","is_ca":false},{"name":"John M. Mariadason","is_ca":false},{"name":"Valerie Montgomery Rice","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04738758097787353,"gpt":0.3776582241281612,"spread":0.3302706431502877,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003932162,0.0002790309,0.000337994,0.0001129078,0.0002087369,0.0000107677,0.0003797592,0.0003375311,0.0001000944],"category_scores_gemma":[0.0000680757,0.0002348722,0.0001546872,0.0002430181,0.0002264826,0.00001464579,0.00004872746,0.0001395328,0.000001196479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002701714,"about_ca_system_score_gemma":0.0006176591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002164165,"about_ca_topic_score_gemma":0.00149486,"domain_scores_codex":[0.9982022,0.0001132252,0.0004445684,0.000607707,0.0001030735,0.0005292275],"domain_scores_gemma":[0.9983559,0.0001673206,0.0002846556,0.000496047,0.000579803,0.0001162712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001511019,0.0001857359,0.002181487,0.00002532531,0.0001296368,3.967942e-7,0.0002634742,0.00001079279,0.9724527,0.00008219657,0.002108732,0.02104853],"study_design_scores_gemma":[0.002116735,0.0005646942,0.004059679,0.00001630174,0.00001208535,0.00000322887,0.0001100606,0.00000463692,0.9671456,0.00006855399,0.02563048,0.0002679971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982346,0.01267122,0.002355132,0.0008559539,0.0004150258,0.0008552147,0.0003191319,0.0000280533,0.0001542437],"genre_scores_gemma":[0.9796889,0.01699077,0.0006162351,0.0005261299,0.0007024598,0.0007384811,0.0002844006,0.00006444923,0.000388179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02352175,"threshold_uncertainty_score":0.9577809,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2048895065","doi":"10.4161/cbt.9.12.11875","title":"Acyl-coenzyme A: Cholesterol acyltransferase inhibitor Avasimibe affect survival and proliferation of glioma tumor cell lines","year":2010,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; University of Chicago","keywords":"Sterol O-acyltransferase; Glioma; Cell growth; Coenzyme A; Affect (linguistics); Cancer research; Acyltransferase; Cholesterol; Chemistry; Cell culture; Biology; Enzyme; Cell biology; Biochemistry; Internal medicine; Medicine; Genetics; Psychology; Reductase; Lipoprotein; Communication","authors":[{"name":"Sana Bemlih","is_ca":true},{"name":"Marie-Denise Poirier","is_ca":false},{"name":"Abdeljabar El Andaloussi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01171610775780649,"gpt":0.2758280517186786,"spread":0.2641119439608721,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002092796,0.0002515035,0.0003338592,0.00006476653,0.00007688916,0.00001793147,0.0001730809,0.0002606761,0.00003953241],"category_scores_gemma":[0.00002097488,0.00020947,0.0001059262,0.00008764547,0.0002855459,0.000009233462,0.00003506427,0.0001814417,0.000001567808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006426862,"about_ca_system_score_gemma":0.0001616628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001116268,"about_ca_topic_score_gemma":0.0005664005,"domain_scores_codex":[0.9988204,0.0000915168,0.0002674978,0.0004650744,0.00007271618,0.0002827559],"domain_scores_gemma":[0.9992874,0.00002242329,0.0001124036,0.0003399685,0.0001343074,0.0001035076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004804665,0.00008127405,0.01165611,0.00002731334,0.00005633107,1.165999e-7,0.0001162576,0.000002171829,0.9799373,0.00004470598,0.001765716,0.005832232],"study_design_scores_gemma":[0.002354649,0.0004288268,0.01077975,0.000008635919,0.00002171167,0.00001004136,0.00002400618,0.000005440437,0.8668076,0.00003463536,0.1193126,0.0002121437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857693,0.006165688,0.0001838363,0.0002614312,0.006974292,0.0004359901,0.0001373015,0.00001898415,0.00005321318],"genre_scores_gemma":[0.9825472,0.004669979,0.0001310614,0.0004826885,0.01181216,0.0001471749,0.00009815173,0.0000341874,0.00007743107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1175469,"threshold_uncertainty_score":0.8541937,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1996695880","doi":"10.4161/cbt.3.10.1113","title":"APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q1","year":2004,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Cancer Institute; National Institutes of Health; American Cancer Society","keywords":"Adenomatous polyposis coli; Methylation; Epigenetics; DNA methylation; Cancer research; Loss of heterozygosity; Biology; Gene silencing; Colorectal cancer; Immunohistochemistry; Molecular biology; Cancer; Allele; Gene expression; Gene; Genetics; Immunology","authors":[{"name":"Christian Arnold","is_ca":false},{"name":"Ajay Goel","is_ca":false},{"name":"Donna Niedzwiecki","is_ca":false},{"name":"Jeannette M. Dowell","is_ca":false},{"name":"L Wasserman","is_ca":false},{"name":"Carolyn C. Compton","is_ca":true},{"name":"Robert J. Mayer","is_ca":false},{"name":"Monica M. Bertagnolli","is_ca":false},{"name":"C. Richard Boland","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01965937616167445,"gpt":0.3058249764731551,"spread":0.2861656003114806,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002169052,0.0002333824,0.0004284644,0.0001335085,0.00005893399,0.000006281273,0.0001957637,0.0002107468,0.0001205665],"category_scores_gemma":[0.00003889431,0.0001331364,0.00006371621,0.0003753922,0.0003268963,0.00002517044,0.00002883627,0.000274095,0.000006704345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006988937,"about_ca_system_score_gemma":0.0005037289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006102049,"about_ca_topic_score_gemma":0.001006915,"domain_scores_codex":[0.9986687,0.000105355,0.0002872277,0.0004155541,0.0001688119,0.0003543666],"domain_scores_gemma":[0.9992303,0.0001055033,0.0001277711,0.0003033326,0.0001537264,0.00007931868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01335714,0.0002253014,0.2538866,0.00003647424,0.0002401001,0.00001960403,0.003038249,0.00636457,0.7013905,0.0001555134,0.0003043798,0.02098162],"study_design_scores_gemma":[0.007334147,0.00462354,0.2231489,0.0004193396,0.00002857653,0.00001605019,0.0001251352,0.00001923552,0.7553248,0.0006722431,0.008051942,0.0002360484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891887,0.002891817,0.0003093313,0.005481975,0.0004207318,0.001511183,0.00004043289,0.00002700176,0.0001288542],"genre_scores_gemma":[0.9957088,0.00109729,0.0003200835,0.002030968,0.0001641729,0.0005874651,0.00002218644,0.00003058596,0.00003843724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05393432,"threshold_uncertainty_score":0.5429143,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011123733","doi":"10.4161/cbt.11.2.13798","title":"Chemo-resistant melanoma sensitized by tamoxifen to low dose curcumin treatment through induction of apoptosis and autophagy","year":2011,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Windsor","funders":"","keywords":"Curcumin; Tamoxifen; Autophagy; Melanoma; Apoptosis; Cancer research; Pharmacology; Programmed cell death; Mitochondrion; Medicine; Curcuma; Cancer; Biology; Breast cancer; Internal medicine; Traditional medicine; Cell biology; Biochemistry","authors":[{"name":"Sudipa June Chatterjee","is_ca":true},{"name":"Siyaram Pandey","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02740427500403875,"gpt":0.2950347879359617,"spread":0.267630512931923,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006812865,0.0001975311,0.0002599725,0.00003253098,0.00005828701,0.000004265683,0.0001300759,0.000248983,0.0001001675],"category_scores_gemma":[0.000008970408,0.0001574925,0.00008081146,0.0001291703,0.0002961697,0.000003588388,0.00004623343,0.00004779041,0.000004693618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004470801,"about_ca_system_score_gemma":0.00006511161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000766547,"about_ca_topic_score_gemma":0.00002535299,"domain_scores_codex":[0.9989732,0.00005747208,0.0002331511,0.0004536884,0.00005194079,0.0002305316],"domain_scores_gemma":[0.9993597,0.00001232318,0.0001110716,0.0003440075,0.0000673902,0.0001054782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004597046,0.0001598765,0.0005720991,0.00000537297,0.000191311,2.567294e-7,0.0004967863,1.33352e-7,0.967052,0.00008327755,0.001132166,0.02984703],"study_design_scores_gemma":[0.001284907,0.0009089859,0.002607895,0.000007320281,0.00002419236,0.000003144266,0.00005646697,0.000001220396,0.9373239,0.0002340766,0.05738717,0.0001606941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942298,0.003413007,0.000836159,0.0005619538,0.0001264637,0.0004309483,0.0002215531,0.00001780667,0.0001623001],"genre_scores_gemma":[0.9944593,0.00280145,0.001168561,0.0006635922,0.000153674,0.0003099869,0.0002047335,0.00002143563,0.0002173066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05625501,"threshold_uncertainty_score":0.6422356,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2325965936","doi":"10.4161/cbt.26723","title":"Blood volatile compounds as biomarkers for colorectal cancer","year":2013,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Advanced Chemical Sensor Technologies","field":"Engineering","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Breath gas analysis; Colorectal cancer; Internal medicine; Exhaled air; Lung cancer; Gastroenterology; Gas chromatography–mass spectrometry; Medicine; Mass spectrometry; Chemistry; Cancer; Chromatography; Toxicology; Biology","authors":[{"name":"Changsong Wang","is_ca":false},{"name":"Peng Li","is_ca":false},{"name":"Ailing Lian","is_ca":false},{"name":"Bo Sun","is_ca":false},{"name":"Xiaoyang Wang","is_ca":false},{"name":"Lei Guo","is_ca":false},{"name":"Chunjie Chi","is_ca":false},{"name":"Shanshan Liu","is_ca":false},{"name":"Wei Zhao","is_ca":false},{"name":"Suqi Luo","is_ca":false},{"name":"Zhigang Guo","is_ca":false},{"name":"Yang Zhang","is_ca":false},{"name":"Chaofu Ke","is_ca":false},{"name":"Guozhu Ye","is_ca":false},{"name":"Guowang Xu","is_ca":false},{"name":"Fengmin Zhang","is_ca":true},{"name":"Enyou Li","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01322146735193873,"gpt":0.2715607282729683,"spread":0.2583392609210295,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000165204,0.0002141481,0.0002537012,0.00005158961,0.00005947229,0.00001326328,0.0002564781,0.0002633471,0.0004553949],"category_scores_gemma":[0.00001360182,0.0001810869,0.00007723126,0.0001426006,0.000225979,0.00006984844,0.00002031241,0.0001426386,0.00002160133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001123776,"about_ca_system_score_gemma":0.00001220842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002111139,"about_ca_topic_score_gemma":0.00003264364,"domain_scores_codex":[0.9991159,0.00000852373,0.0001722655,0.0002537137,0.00003795581,0.0004116214],"domain_scores_gemma":[0.9995657,0.0001070041,0.00004014944,0.0001720386,0.0000605729,0.00005452241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000365243,0.00001350883,0.004017348,0.000009948192,0.0002876616,2.52424e-7,0.00003761845,0.0001802988,0.9501867,0.0001030018,0.004027826,0.04109931],"study_design_scores_gemma":[0.001029785,0.0001422427,0.0009867696,0.00001298968,0.00001573072,0.000002018182,0.00003823153,0.0009732833,0.9429149,0.006204624,0.04738576,0.000293677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868715,0.009937559,0.0002574522,0.0004924717,0.0005273211,0.0005401943,0.00007871225,0.000842904,0.0004519029],"genre_scores_gemma":[0.9917016,0.004984116,0.001009127,0.0002571982,0.000154322,0.001742213,0.00002392302,0.00005108695,0.00007643039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04335794,"threshold_uncertainty_score":0.7384511,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2060763507","doi":"10.4161/cbt.9.11.11882","title":"MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity","year":2010,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Bortezomib; Mdm2; Proteasome inhibitor; Proteasome; Pharmacology; Cancer research; Apoptosis; Multiple myeloma; Viability assay; Chemistry; Medicine; Immunology","authors":[{"name":"Manujendra N. Saha","is_ca":true},{"name":"Hua Jiang","is_ca":false},{"name":"Jennifer Jayakar","is_ca":false},{"name":"Donna Reece","is_ca":false},{"name":"Donald R. Branch","is_ca":false},{"name":"Hong Chang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01758960195250794,"gpt":0.3042208287082948,"spread":0.2866312267557869,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000221358,0.0003371869,0.0005546212,0.0001541057,0.0001949224,0.00002554586,0.0001966176,0.0005419191,0.0002451268],"category_scores_gemma":[0.00007990114,0.0002893099,0.000159939,0.0003144079,0.0004841366,0.00007883089,0.00004671065,0.0009498866,0.00004552421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003227585,"about_ca_system_score_gemma":0.0006405853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000319145,"about_ca_topic_score_gemma":0.0001306647,"domain_scores_codex":[0.9982907,0.0001136081,0.0002929601,0.0006237293,0.0001840808,0.0004949605],"domain_scores_gemma":[0.9988012,0.00006323122,0.0002163218,0.0005598665,0.0001598882,0.0001995483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009067722,0.0002628904,0.005894059,0.00003734639,0.0001725645,0.00003439787,0.0001758932,0.000005350765,0.9627226,0.0007579035,0.0004096842,0.02862052],"study_design_scores_gemma":[0.01041643,0.001266462,0.09544416,0.000160943,0.0001205873,0.0001038545,0.00002709763,0.0006924319,0.8470836,0.0003988365,0.04370523,0.0005803218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990845,0.001532328,0.0006063241,0.002577492,0.002409946,0.00145197,0.0001158267,0.0001864605,0.0002746387],"genre_scores_gemma":[0.9965317,0.0007659781,0.0001409076,0.0007531586,0.000808789,0.0005182634,0.0001238999,0.00007061276,0.0002866389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.115639,"threshold_uncertainty_score":0.9999559,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2113386816","doi":"10.4161/cbt.3.12.1238","title":"Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression","year":2004,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; Public Health Agency of Canada","keywords":"Serial analysis of gene expression; Biology; SAGE; DNA microarray; Gene; Pancreatic cancer; Transcriptome; Gene expression; Gene expression profiling; Computational biology; Genetics; Cancer","authors":[{"name":"Steven R. Hustinx","is_ca":false},{"name":"Dengfeng Cao","is_ca":false},{"name":"Anirban Maitra","is_ca":false},{"name":"Norihiro Sato","is_ca":false},{"name":"Seán Martin","is_ca":false},{"name":"D. Sudhir","is_ca":false},{"name":"Christine A. Iacobuzio–Donahue","is_ca":false},{"name":"John L. Cameron","is_ca":false},{"name":"Charles J. Yeo","is_ca":false},{"name":"Scott E. Kern","is_ca":false},{"name":"Michael Goggins","is_ca":false},{"name":"Jan Mollenhauer","is_ca":false},{"name":"Akhilesh Pandey","is_ca":false},{"name":"Ralph H. Hruban","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0561451700874578,"gpt":0.3684172466672599,"spread":0.3122720765798022,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001893007,0.0002142665,0.001130472,0.0003244349,0.00005850623,0.000007221401,0.0002045092,0.0002538076,0.0009219393],"category_scores_gemma":[0.00002847412,0.0001598451,0.0002199575,0.0006098458,0.0003501755,0.00005950019,0.00004170738,0.0001852803,0.000005602276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487145,"about_ca_system_score_gemma":0.0003700984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001715651,"about_ca_topic_score_gemma":0.000239065,"domain_scores_codex":[0.998261,0.0001917064,0.0005059345,0.0004611916,0.0001769957,0.0004032201],"domain_scores_gemma":[0.9990541,0.0001050355,0.0001724017,0.0004556139,0.0001199038,0.00009292753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001277753,0.0001923423,0.4568747,0.00001361266,0.001135627,0.00002472094,0.001307229,0.00003723069,0.5386112,0.00005614881,0.00001059926,0.000458783],"study_design_scores_gemma":[0.005504674,0.0004353381,0.7135099,0.00006289277,0.000638605,0.000006234236,0.0001631771,0.00002190945,0.278688,0.0007930481,0.00004345468,0.0001328108],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853977,0.01186462,0.001401407,0.0002940276,0.0002770224,0.0005398279,0.00005278164,0.00002619651,0.0001463965],"genre_scores_gemma":[0.9906941,0.006989516,0.00132593,0.0001678911,0.000210181,0.0002424026,0.0001250216,0.00002050012,0.0002244508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2599232,"threshold_uncertainty_score":0.9999914,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1975263280","doi":"10.4161/cbt.5.1.2400","title":"Cancer-selective therapy of the future: Apoptin and its mechanism of action","year":2006,"lang":"en","type":"review","venue":"Cancer Biology & Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"CancerCare Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Cancer; Mechanism (biology); Cancer cell; Cancer research; Biology; Mechanism of action; Cancer therapy; Bioinformatics; Genetics; In vitro","authors":[{"name":"Subbareddy Maddika","is_ca":true},{"name":"Francisco J. Mendoza","is_ca":false},{"name":"Kristin Hauff","is_ca":false},{"name":"Christina R. Zamzow","is_ca":false},{"name":"Ted Paranjothy","is_ca":false},{"name":"Marek Łoś","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05662188961185748,"gpt":0.392826461570645,"spread":0.3362045719587876,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000312707,0.0004719589,0.001061383,0.0001114092,0.0001027963,0.000007109286,0.0006126197,0.000811991,0.00006636813],"category_scores_gemma":[0.000007682585,0.0003001802,0.0004431964,0.0003492062,0.0002765114,0.000003612347,0.00009400233,0.0003680512,8.550869e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000773911,"about_ca_system_score_gemma":0.0008518157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001532418,"about_ca_topic_score_gemma":0.0004567805,"domain_scores_codex":[0.9976923,0.0006455859,0.0004937259,0.0006413001,0.0001499595,0.0003770778],"domain_scores_gemma":[0.9984321,0.00003873356,0.0006657991,0.0005633818,0.0002467456,0.00005324787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006775695,0.00005823953,0.00003065911,0.0003489398,0.0007699416,1.490488e-7,0.00002626295,0.00000220879,0.2002314,0.00009757533,0.0002880926,0.7974689],"study_design_scores_gemma":[0.000749277,0.001510302,0.00002371125,0.0002994408,0.00005879638,0.000004536127,0.000009579172,0.000001182302,0.3358066,0.0001487593,0.6611155,0.0002723336],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04035567,0.9573079,0.00001102889,0.0001047791,0.0005898267,0.001219842,0.0003634364,0.000008802626,0.0000387563],"genre_scores_gemma":[0.007195395,0.9906803,0.00001089053,0.0001461257,0.0009624462,0.0005890157,0.0001134955,0.00007738359,0.000224977],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7971966,"threshold_uncertainty_score":0.999945,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1565605167","doi":"10.1080/15384047.2015.1046652","title":"A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients","year":2015,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Chemoradiotherapy; Colorectal cancer; XRCC3; Medicine; Oncology; Cancer; Internal medicine; Bioinformatics; Gene; Biology; Genotype","authors":[{"name":"Marco Agostini","is_ca":false},{"name":"Andrea Zangrando","is_ca":false},{"name":"Chiara Pastrello","is_ca":true},{"name":"Edoardo D’Angelo","is_ca":false},{"name":"Gabriele Romano","is_ca":false},{"name":"Roberto Giovannoni","is_ca":false},{"name":"Marco Giordan","is_ca":false},{"name":"Isacco Maretto","is_ca":false},{"name":"Chiara Bedin","is_ca":false},{"name":"Carlo Zanon","is_ca":false},{"name":"Maura Digito","is_ca":false},{"name":"Giovanni Esposito","is_ca":false},{"name":"Claudia Mescoli","is_ca":false},{"name":"Marialuisa Lavitrano","is_ca":false},{"name":"Flavio Rizzolio","is_ca":false},{"name":"Igor Jurišica","is_ca":true},{"name":"Antonio Giordano","is_ca":false},{"name":"Salvatore Pucciarelli","is_ca":false},{"name":"Donato Nitti","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0902267420582947,"gpt":0.3375165638384778,"spread":0.2472898217801831,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001825245,0.0002998525,0.0007283966,0.0001058132,0.00003549856,0.000006186631,0.0001392323,0.0002710714,0.001095117],"category_scores_gemma":[0.00003810402,0.000213157,0.0001587062,0.000525103,0.0001983226,0.00004190179,0.00002700728,0.0002442981,0.000009626196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007686732,"about_ca_system_score_gemma":0.000543021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005582673,"about_ca_topic_score_gemma":0.0004831285,"domain_scores_codex":[0.998166,0.000166538,0.0004160531,0.0005624075,0.0002068489,0.000482157],"domain_scores_gemma":[0.999009,0.0001081382,0.0001926244,0.0002690851,0.0001667709,0.000254349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03490517,0.0005802532,0.9271538,0.00000889967,0.0002841838,0.00001101819,0.0002256683,0.00002996127,0.001305748,0.00008093681,0.009661295,0.02575302],"study_design_scores_gemma":[0.01760412,0.002782027,0.9355956,0.0002311057,0.00001882681,0.000002634726,0.00001419613,0.00001075381,0.001671735,0.001054441,0.04076795,0.0002466019],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773807,0.01756956,0.00001189911,0.001358257,0.001050056,0.0007334353,0.00007073938,0.00004684287,0.001778507],"genre_scores_gemma":[0.989388,0.005711458,0.0003342199,0.002188061,0.0006602807,0.0003209867,0.00009743587,0.0000352463,0.001264321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03110665,"threshold_uncertainty_score":0.999818,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2015971779","doi":"10.4161/cbt.7.12.6984","title":"Molecular identity of a pan cancer marker, CA215","year":2008,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Epitope; Antibody; Chemistry; Monoclonal antibody; Molecular biology; Antigen; Western blot; Cancer cell; Molecular mass; Biochemistry; Glycan; Cancer; Biology; Enzyme; Immunology; Glycoprotein; Gene","authors":[{"name":"Gregory Lee","is_ca":true},{"name":"Emily Laflamme","is_ca":false},{"name":"Chin-Hsiang Chien","is_ca":false},{"name":"Hong Hoi Ting","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03135725755647932,"gpt":0.3510615530449256,"spread":0.3197042954884463,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001403503,0.0001478328,0.0001980153,0.000060902,0.0000832775,0.000005014171,0.0002819846,0.0002022429,0.0004350354],"category_scores_gemma":[0.00002519299,0.000128731,0.0001195801,0.0001652599,0.0003109423,0.000005474615,0.00006928509,0.0001075131,0.000007480497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002438301,"about_ca_system_score_gemma":0.0002530145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001056013,"about_ca_topic_score_gemma":0.0002973414,"domain_scores_codex":[0.9989321,0.0001246517,0.0002003489,0.0003418417,0.0001197989,0.0002813063],"domain_scores_gemma":[0.9992785,0.000007638155,0.00009301988,0.0003535304,0.0001939034,0.00007344411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002825932,0.00005066395,0.05970713,0.000008041529,0.0001373335,0.000004536786,0.00004928216,0.0000221078,0.9238614,0.0001318748,0.0009283807,0.01481668],"study_design_scores_gemma":[0.001336078,0.0003180532,0.04201682,0.00001121329,0.000006509465,0.00001057465,0.00001608779,0.00001903378,0.8374428,0.0001832865,0.1184317,0.0002078738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752263,0.02281098,0.0006026718,0.0003383664,0.0001832904,0.0002788863,0.00007046317,0.0000113157,0.0004777299],"genre_scores_gemma":[0.9704696,0.02774941,0.0001011771,0.000614878,0.0001517228,0.0001776379,0.00006006463,0.00002036304,0.0006551412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1175033,"threshold_uncertainty_score":0.5249498,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1507647676","doi":"10.1080/15384047.2015.1040957","title":"Microarray expression profiling of dysregulated long non-coding RNAs in triple-negative breast cancer","year":2015,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Triple-negative breast cancer; Breast cancer; KEGG; Cancer research; Carcinogenesis; Metastasis; Long non-coding RNA; Microarray; Biology; Gene expression profiling; Microarray analysis techniques; Cancer; Gene expression; Computational biology; Bioinformatics; Gene; RNA; Transcriptome; Genetics","authors":[{"name":"Chen Chen","is_ca":false},{"name":"Zhilu Li","is_ca":false},{"name":"Yuan Yang","is_ca":false},{"name":"Tingxiu Xiang","is_ca":false},{"name":"Weihong Song","is_ca":true},{"name":"Shengchun Liu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02653408398810411,"gpt":0.3319312185800438,"spread":0.3053971345919397,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003825833,0.0002720609,0.0003786812,0.0001711425,0.00005461176,0.00001206538,0.0003635985,0.0004506646,0.0001025398],"category_scores_gemma":[0.00004007035,0.0002395512,0.0001114375,0.0003571459,0.0002263265,0.000009519047,0.000124023,0.0002825667,0.000003021543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001833106,"about_ca_system_score_gemma":0.0006470139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008297295,"about_ca_topic_score_gemma":0.0003079244,"domain_scores_codex":[0.9981169,0.0002247056,0.0003766966,0.0006190919,0.0001561101,0.000506488],"domain_scores_gemma":[0.9988884,0.0000174642,0.0002063837,0.0004021017,0.0003388585,0.0001467449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001540955,0.00006735742,0.003195232,0.00001719676,0.000126492,0.000004737218,0.0002674618,0.0004884453,0.9819778,0.0000118677,0.0003273877,0.01197504],"study_design_scores_gemma":[0.003807731,0.0002905736,0.002199196,0.000135655,0.000009101827,0.00001118479,0.0001429263,0.0001620573,0.9921314,0.0001037877,0.0007431277,0.0002632854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9755671,0.01038241,0.01177602,0.0003374452,0.0006566186,0.0009178336,0.0001742305,0.00001948976,0.0001688225],"genre_scores_gemma":[0.9933822,0.004927456,0.000508377,0.0002257559,0.0002809408,0.0003050722,0.0001064109,0.00005350316,0.0002102832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01781507,"threshold_uncertainty_score":0.9768615,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2007843050","doi":"10.4161/cbt.8.2.7134","title":"TMPRSS2-ERG fusion is frequently observed in gleason pattern 3 prostate cancer in a Canadian cohort","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Jewish General Hospital","funders":"","keywords":"TMPRSS2; Erg; Prostate cancer; Fusion gene; Medicine; Oncology; Biomarker; Cohort; Prostate; Internal medicine; Cancer; Prostatectomy; Cancer research; Biology; Gene; Ophthalmology; Genetics; Disease","authors":[{"name":"Andrew D. Darnel","is_ca":true},{"name":"Christopher J. Lafargue","is_ca":false},{"name":"Robin T. Vollmer","is_ca":false},{"name":"Jacques Corcos","is_ca":false},{"name":"Tarek A. Bismar","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04285329293288444,"gpt":0.3535177329741073,"spread":0.3106644400412229,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002459069,0.0002745489,0.0004874603,0.0003464009,0.00007149203,0.00001601169,0.0001701596,0.0002627101,0.001288784],"category_scores_gemma":[0.000008197295,0.0002074597,0.00008244782,0.0005067449,0.0001195197,0.00007205878,0.00001443355,0.0003980962,0.00001740057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001770036,"about_ca_system_score_gemma":0.001774459,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.5549574,"about_ca_topic_score_gemma":0.5417085,"domain_scores_codex":[0.9978942,0.0001050556,0.0003200017,0.0005712342,0.0001472767,0.0009622225],"domain_scores_gemma":[0.9991596,0.00002117839,0.00006899789,0.000311013,0.0001037702,0.0003353825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006164705,0.00009114236,0.7733735,0.0000131468,0.0000678635,0.0001137026,0.001024407,0.00000582083,0.01682255,0.000006330273,0.0006462258,0.2072188],"study_design_scores_gemma":[0.006001794,0.0006738596,0.9564612,0.0002819268,0.00001540218,0.000004459565,0.00006665359,0.000115533,0.00567848,0.0001895925,0.03027178,0.0002393499],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9409472,0.03704831,0.000001228079,0.0195644,0.0002738228,0.001477222,0.0001943708,0.00003108455,0.000462359],"genre_scores_gemma":[0.9249942,0.06660786,0.00001325023,0.006627727,0.0001631295,0.0005371579,0.000136212,0.00002605296,0.0008943623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2069795,"threshold_uncertainty_score":0.9996242,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2052388653","doi":"10.4161/cbt.8.7.7853","title":"Peroxisome proliferator-activated receptor γ in bladder cancer: A promising therapeutic target","year":2009,"lang":"en","type":"review","venue":"Cancer Biology & Therapy","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre","funders":"Cancer Research Society","keywords":"Peroxisome proliferator-activated receptor; Nuclear receptor; Cancer research; Carcinogenesis; Biology; Receptor; Troglitazone; Oncogene; Peroxisome proliferator-activated receptor gamma; Transcription factor; Cancer; Biochemistry; Gene; Cell cycle; Genetics","authors":[{"name":"José João Mansure","is_ca":true},{"name":"Roland Nassim","is_ca":false},{"name":"Wassim Kassouf","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04596655172985199,"gpt":0.3621305086392062,"spread":0.3161639569093542,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0004227625,0.001481025,0.002615633,0.0004455097,0.0001969244,0.00007983277,0.001050677,0.002376421,0.0006020561],"category_scores_gemma":[0.00004414695,0.001181741,0.0006804269,0.0008850846,0.0003559156,0.0000221762,0.0001360308,0.001247245,0.00003497563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000575304,"about_ca_system_score_gemma":0.002242045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009578098,"about_ca_topic_score_gemma":0.00003705954,"domain_scores_codex":[0.994269,0.001037794,0.001177151,0.00196301,0.0002170801,0.001335976],"domain_scores_gemma":[0.9977029,0.00005160682,0.0007760254,0.0009946199,0.000205591,0.0002692865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003638547,0.0002751167,0.0006402826,0.000521291,0.001397527,0.000003847211,0.0001149643,0.000007246473,0.2228433,0.00001244742,0.0009724204,0.7728477],"study_design_scores_gemma":[0.001297616,0.000607272,0.00001535453,0.001632747,0.0001079258,0.00001626148,0.00001815225,0.000001811313,0.07120294,0.00005207143,0.9237779,0.001269931],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02055734,0.9748161,0.00001975538,0.000225911,0.001124639,0.002698342,0.0003625619,0.0001109282,0.00008444655],"genre_scores_gemma":[0.002086376,0.9899639,0.0001797805,0.001196279,0.001728048,0.003114,0.001087251,0.0002926627,0.0003516553],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9228055,"threshold_uncertainty_score":0.9997939,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2021343953","doi":"10.4161/cbt.8.24.9987","title":"Inhibition of mammalian target of rapamycin as a therapeutic strategy in the management of bladder cancer","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"PI3K/AKT/mTOR pathway; Everolimus; Apoptosis; Angiogenesis; Cancer research; In vivo; Cell growth; Bladder cancer; In vitro; Cell culture; Cancer; Pharmacology; Medicine; Chemistry; Biology; Internal medicine; Biochemistry","authors":[{"name":"José João Mansure","is_ca":true},{"name":"Roland Nassim","is_ca":false},{"name":"Simone Chevalier","is_ca":false},{"name":"Joice Rocha","is_ca":false},{"name":"Eleonora Scarlata","is_ca":false},{"name":"Wassim Kassouf","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02374667315045228,"gpt":0.3232176874424791,"spread":0.2994710142920268,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002980018,0.0001818177,0.0002821323,0.00006683735,0.00002221917,0.000003313394,0.0003005714,0.0001916702,0.0002384253],"category_scores_gemma":[0.000001926432,0.0001329513,0.0001145678,0.0002115609,0.0002300618,0.000004361184,0.00001940904,0.0001020377,7.531292e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002661726,"about_ca_system_score_gemma":0.0001287573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002496709,"about_ca_topic_score_gemma":0.00006528692,"domain_scores_codex":[0.9987915,0.0001670087,0.000386068,0.000301739,0.0001133608,0.0002402953],"domain_scores_gemma":[0.9992543,0.00001316384,0.0002373324,0.0003716046,0.0001001765,0.00002336446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005814716,0.0001553301,0.005063029,0.00003519292,0.0002951693,0.000001836775,0.0003089298,0.0006673324,0.9635667,0.0006175897,0.0001935927,0.02851385],"study_design_scores_gemma":[0.001748287,0.001504347,0.02535007,0.00008763294,0.00003921331,0.000002317195,0.0003195039,0.00001197893,0.9633448,0.002780454,0.004623878,0.0001874817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714176,0.02653146,0.0001733477,0.0004360597,0.0001193261,0.0003875761,0.00007093193,0.000004434602,0.0008592427],"genre_scores_gemma":[0.9882717,0.01015038,0.0001036246,0.001118212,0.0001048637,0.0001057884,0.00004464342,0.0000142318,0.00008655499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02832637,"threshold_uncertainty_score":0.5421599,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2000493107","doi":"10.4161/cbt.9.9.11432","title":"MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity","year":2010,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Tamoxifen; Estrogen; Cancer research; Biology; Breast cancer; Estrogen receptor; Phenotype; Cell culture; Aromatase; Internal medicine; Cell growth; Aromatase inhibitor; Cancer; Endocrinology; Medicine; Gene; Genetics","authors":[{"name":"Euphemia Leung","is_ca":false},{"name":"Nagarajan Kannan","is_ca":true},{"name":"Geoffrey W. Krissansen","is_ca":false},{"name":"Michael Findlay","is_ca":false},{"name":"Bruce C. Baguley","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009096175471917847,"gpt":0.2498819291119252,"spread":0.2407857536400074,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001351565,0.000247633,0.0002869692,0.00003472787,0.0001075828,0.00001778442,0.00008855927,0.0004150039,0.00001458019],"category_scores_gemma":[0.00001595109,0.0001946203,0.0000466483,0.0000892112,0.0002044533,0.000007885877,0.00004686722,0.0002023145,3.260079e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001624745,"about_ca_system_score_gemma":0.0001164368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003723556,"about_ca_topic_score_gemma":0.001134903,"domain_scores_codex":[0.9988214,0.00009329192,0.0001728934,0.0005236701,0.00003812694,0.0003506438],"domain_scores_gemma":[0.9994377,0.00005029413,0.00009869943,0.0002031721,0.00008364717,0.0001264226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001173713,0.00003109682,0.02676959,0.00001845044,0.0000743605,0.000002057958,0.0001486203,0.000002362475,0.960472,0.00001273091,0.0005813811,0.01071365],"study_design_scores_gemma":[0.002443988,0.0001298401,0.04926609,0.0000393874,0.00001578519,0.00001024558,0.00002139053,0.00002268839,0.9433053,0.00007159693,0.004416921,0.0002568296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802772,0.01807811,0.0001254562,0.0005449994,0.0003383736,0.000467498,0.000136858,0.00002008052,0.00001139377],"genre_scores_gemma":[0.9888554,0.009639174,0.000232918,0.0004321057,0.000315561,0.0001174227,0.0000476863,0.00003409962,0.0003255841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02249649,"threshold_uncertainty_score":0.7936383,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2085065223","doi":"10.4161/cbt.10.6.12535","title":"Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma","year":2010,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network; Toronto General Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Apoptosis; Downregulation and upregulation; Survivin; Puma; Mdm2; Proteasome inhibitor; Cancer research; Inhibitor of apoptosis domain; Intrinsic apoptosis; Cell biology; Proteasome; Biology; Cytochrome c; Chemistry; Caspase; Programmed cell death; Biochemistry; Gene","authors":[{"name":"Manujendra N. Saha","is_ca":true},{"name":"Hua Jiang","is_ca":true},{"name":"Hong Chang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02344463278344112,"gpt":0.2934818845958674,"spread":0.2700372518124263,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001787856,0.0002134909,0.0004672472,0.0001970023,0.00002903121,0.000003325407,0.0001779609,0.0004365799,0.0002740657],"category_scores_gemma":[0.00005491195,0.0001881807,0.0001538518,0.0003170147,0.0001362659,0.00002266298,0.00003112564,0.000511936,0.00001089833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007990617,"about_ca_system_score_gemma":0.0002539019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004745594,"about_ca_topic_score_gemma":0.0002540756,"domain_scores_codex":[0.998736,0.00006683893,0.0003342484,0.0004051113,0.0001135949,0.0003441682],"domain_scores_gemma":[0.9990864,0.0000440169,0.000135739,0.000512263,0.0001154276,0.0001061824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003866562,0.0001509601,0.0035515,0.00001194639,0.0001281768,0.000009891028,0.0001815085,0.00000872175,0.964856,0.001172663,0.00002630314,0.02951564],"study_design_scores_gemma":[0.004222691,0.0005320022,0.004949106,0.00004857943,0.0000271473,0.00001107434,0.00003549152,0.0001026161,0.9866136,0.001232608,0.002050295,0.0001747761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949028,0.001250067,0.00109189,0.0008401636,0.0009486347,0.0006331619,0.00002488924,0.00005703271,0.0002513004],"genre_scores_gemma":[0.9967536,0.0005390518,0.001109653,0.001214492,0.00009750454,0.0001920141,0.00002839565,0.00004775232,0.00001747746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02934086,"threshold_uncertainty_score":0.7673786,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1987882758","doi":"10.4161/cbt.3.1.590","title":"Evaluation of Microsatellite Instability, hMLH1 Expression and hMLH1 Promoter Hypermethylation in Defining the MSI Phenotype of Colorectal Cancer","year":2004,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Cancer Institute; University of California, San Francisco; University of California, San Diego","keywords":"Microsatellite instability; DNA mismatch repair; Methylation; DNA methylation; Colorectal cancer; Biology; Cancer research; Cancer; Immunohistochemistry; Microsatellite; Molecular biology; Gene; Gene expression; Genetics; Allele; Immunology","authors":[{"name":"Christian Arnold","is_ca":false},{"name":"Ajay Goel","is_ca":false},{"name":"Carolyn C. Compton","is_ca":true},{"name":"Victoria Marcus","is_ca":true},{"name":"Donna Niedzwiecki","is_ca":false},{"name":"Jeannette M. Dowell","is_ca":false},{"name":"L Wasserman","is_ca":false},{"name":"Toru Inoue","is_ca":false},{"name":"Robert J. Mayer","is_ca":false},{"name":"Monica M. Bertagnolli","is_ca":false},{"name":"C. Richard Boland","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04622564561595165,"gpt":0.3539324704548627,"spread":0.307706824838911,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007662073,0.0001559465,0.0003409423,0.00009008018,0.00003931008,0.000003744542,0.00009615842,0.0001876815,0.0001741494],"category_scores_gemma":[0.000101991,0.0001028795,0.00005196681,0.0002379355,0.0004059201,0.00003995673,0.00002508703,0.0001786014,5.775322e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003087781,"about_ca_system_score_gemma":0.0005823961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008546181,"about_ca_topic_score_gemma":0.0005953272,"domain_scores_codex":[0.998696,0.0002532551,0.0003096261,0.0003072169,0.0002411825,0.0001927713],"domain_scores_gemma":[0.9990425,0.0001041753,0.0002092713,0.0002034275,0.0004053348,0.00003528274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006079589,0.00006079686,0.1892815,0.00002797604,0.00004666754,1.531511e-7,0.002080906,0.0003409521,0.7266869,0.00002374105,0.000003957889,0.08083845],"study_design_scores_gemma":[0.002811522,0.0004784176,0.4463454,0.0001529751,0.00005799222,0.000002393494,0.000140613,0.00007998868,0.5486277,0.001126604,0.00009400345,0.00008236873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9647696,0.03325045,0.00001648494,0.000482401,0.0002988487,0.0009909422,0.0000296198,0.00001026461,0.0001513919],"genre_scores_gemma":[0.996676,0.002342209,0.0005064348,0.0001342198,0.00004755454,0.0002579496,0.00001357853,0.00001754404,0.000004553444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2570639,"threshold_uncertainty_score":0.4195303,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2046878463","doi":"10.4161/cbt.3.10.1112","title":"Role of caveolin-1 in etoposide resistance development in A549 lung cancer cells","year":2004,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Etoposide; Lung cancer; Cancer research; A549 cell; Caveolin 1; Medicine; Biology; Cell biology; Chemistry; Oncology; Internal medicine; Chemotherapy","authors":[{"name":"Martin M. Bélanger","is_ca":true},{"name":"Martin Gaudreau","is_ca":false},{"name":"Élise Roussel","is_ca":false},{"name":"Jacques Couët","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006945214565507432,"gpt":0.2703541009009733,"spread":0.2634088863354658,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001490881,0.00019045,0.0002654555,0.00008413888,0.00003231742,0.000004787343,0.000237201,0.0002383032,0.00004897351],"category_scores_gemma":[0.000006739739,0.0001776606,0.00005530917,0.0001822229,0.0001272592,0.000003858312,0.00004550046,0.0001261956,0.000001552482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001143885,"about_ca_system_score_gemma":0.0006243206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008373572,"about_ca_topic_score_gemma":0.01222841,"domain_scores_codex":[0.9987964,0.00004313744,0.0003480019,0.0004108617,0.00006422205,0.0003373913],"domain_scores_gemma":[0.9995258,0.000008916115,0.0001191399,0.0002259422,0.00007324224,0.00004693952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002959217,0.000085031,0.03519677,0.00003175061,0.00004762457,0.000002784987,0.0005460414,0.000455084,0.9589794,0.00009433946,0.00004176502,0.004223494],"study_design_scores_gemma":[0.001530132,0.00005306343,0.007265004,0.00007980161,0.000004044097,8.801394e-7,0.00007579199,0.000002436209,0.9607808,0.0003801229,0.02961739,0.0002105126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9146859,0.08437818,0.00009059469,0.0001652337,0.0001465184,0.0002224019,0.00002433244,0.000006126244,0.0002807081],"genre_scores_gemma":[0.978157,0.02043593,0.0002888145,0.0004466843,0.000117621,0.0002016511,0.00004041263,0.00002183155,0.000290027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06394225,"threshold_uncertainty_score":0.724479,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2081338931","doi":"10.4161/cbt.8.21.9803","title":"Triptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Natural Compounds in Disease Treatment","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"ADAM10; Triptolide; Chemistry; Cancer research; Cancer cell; Molecular biology; Apoptosis; Disintegrin; Metalloproteinase; Biology; Cancer; Biochemistry; Internal medicine; Matrix metalloproteinase; Medicine","authors":[{"name":"Ramani Soundararajan","is_ca":true},{"name":"Ria Sayat","is_ca":false},{"name":"George S. Robertson","is_ca":false},{"name":"Paola A. Marignani","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03794065110330194,"gpt":0.3744694497610418,"spread":0.3365287986577399,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009798675,0.000201367,0.0004804888,0.0001541818,0.00002531005,0.000005212083,0.00009104209,0.0001372715,0.0005686656],"category_scores_gemma":[0.000008452941,0.00013779,0.00007748679,0.0002265304,0.0001569489,0.00005751818,0.00001293789,0.0001707094,0.00000162809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001788418,"about_ca_system_score_gemma":0.0001441549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006350389,"about_ca_topic_score_gemma":0.0001910471,"domain_scores_codex":[0.9989883,0.00008724947,0.0002575556,0.000345633,0.00008384461,0.000237435],"domain_scores_gemma":[0.9994009,0.00002770479,0.00009487391,0.0002715375,0.0000744707,0.0001305614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002959009,0.0005669778,0.01305254,0.00001811587,0.0001475365,0.0000329742,0.0002603625,0.00000265392,0.7423044,0.000116559,0.0003501736,0.2401886],"study_design_scores_gemma":[0.01320956,0.005235889,0.1907683,0.0002844443,0.0001634723,0.00001529592,0.000110244,0.00005029137,0.7739753,0.00216523,0.01359144,0.0004305881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9587959,0.03872896,0.000002377513,0.001630326,0.0001667621,0.0004811606,0.00004844034,0.00002784087,0.0001182307],"genre_scores_gemma":[0.9931828,0.004760956,0.0003342453,0.001000906,0.0001709773,0.000115604,0.00002363885,0.00001349917,0.0003973873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.239758,"threshold_uncertainty_score":0.6226489,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2031187947","doi":"10.4161/cbt.7.3.5364","title":"Synergy of pancratistatin and tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria","year":2008,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":52,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Windsor","funders":"Wayne State University","keywords":"Apoptosis; Tamoxifen; Estrogen receptor; Mitochondrion; Cancer cell; Cancer research; Biology; Reactive oxygen species; Cell culture; Cell biology; Cancer; Chemistry; Breast cancer; Biochemistry; Genetics","authors":[{"name":"Peter Siedlakowski","is_ca":true},{"name":"Amanda McLachlan-Burgess","is_ca":false},{"name":"Carly Griffin","is_ca":false},{"name":"Sridhar S. Tirumalai","is_ca":false},{"name":"James McNulty","is_ca":false},{"name":"Siyaram Pandey","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01270408242990901,"gpt":0.2487525960684829,"spread":0.2360485136385739,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005428839,0.0001916645,0.0003590806,0.00002946197,0.00006054431,0.000005251998,0.0001400759,0.0001976491,0.001166845],"category_scores_gemma":[0.00001086751,0.0001578667,0.00005076849,0.0001016769,0.0001865922,0.00003023608,0.00002392619,0.000191922,0.000001169667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008478753,"about_ca_system_score_gemma":0.00005052985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002330346,"about_ca_topic_score_gemma":0.00003686412,"domain_scores_codex":[0.9989463,0.00003544979,0.0002979662,0.0003713339,0.00006855255,0.0002804003],"domain_scores_gemma":[0.9994442,0.0001546128,0.0001523741,0.0001533091,0.00003070989,0.00006476609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001205064,0.00006137396,0.02721543,0.00001745875,0.00004709151,7.535348e-7,0.0002947988,0.000006728313,0.9483573,0.00001426862,0.002149989,0.02171428],"study_design_scores_gemma":[0.0007066737,0.00002222405,0.001391965,0.00009971393,0.000004785694,0.000001462681,0.00005291335,0.00001853369,0.9931707,0.00005428136,0.004291892,0.0001848633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994984,0.003814888,0.000005444576,0.0003157409,0.00009579152,0.00005362786,0.0004421047,0.00001846613,0.0002698794],"genre_scores_gemma":[0.9888914,0.0102096,0.00009839419,0.0003161203,0.000180448,0.0001004683,0.00003020853,0.00002349724,0.000149817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04481337,"threshold_uncertainty_score":0.9997462,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2130952471","doi":"10.1080/15384047.2015.1095402","title":"microRNA-622 acts as a tumor suppressor in hepatocellular carcinoma","year":2015,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"University of Lethbridge; National Science Foundation","keywords":"microRNA; Cancer research; Ectopic expression; Hepatocellular carcinoma; Downregulation and upregulation; Apoptosis; Cell growth; Suppressor; Transfection; Biology; Cell culture; Cancer; Gene","authors":[{"name":"Weihua Song","is_ca":false},{"name":"Xiaojun Feng","is_ca":false},{"name":"Shao-Juan Gong","is_ca":false},{"name":"Jianming Chen","is_ca":false},{"name":"Shou‐Mei Wang","is_ca":false},{"name":"Dong-Juan Xing","is_ca":false},{"name":"Ming-hua Zhu","is_ca":false},{"name":"Shu‐Hui Zhang","is_ca":false},{"name":"Ai-Min Xu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02787294498054428,"gpt":0.2917784695043266,"spread":0.2639055245237824,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001726629,0.0002075099,0.0002087008,0.00006687229,0.00003285033,0.0000128882,0.0002700741,0.0002054667,0.00009742939],"category_scores_gemma":[0.0000365721,0.0001910378,0.00008347916,0.0001083185,0.0001398316,0.000004838713,0.00007038281,0.00009716921,0.00003111512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008398391,"about_ca_system_score_gemma":0.0004128835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002671515,"about_ca_topic_score_gemma":0.0000663368,"domain_scores_codex":[0.9987507,0.000151347,0.0002188201,0.0004634595,0.00006510282,0.0003504997],"domain_scores_gemma":[0.9992283,0.000008516179,0.0001014511,0.0004074337,0.0001029412,0.0001513834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004454915,0.00005626454,0.1258461,0.000005127498,0.00004078993,0.00001251564,0.0001055049,0.00001550769,0.8713697,0.00004705178,0.001502959,0.0005529977],"study_design_scores_gemma":[0.00216324,0.0002918067,0.02072543,0.00001129314,0.000008219788,0.00002042482,0.00004260627,0.00004964987,0.835887,0.0003863129,0.1401537,0.0002602551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807785,0.01781861,0.00003965165,0.0003528625,0.0003076259,0.0003604662,0.000044631,0.00001660732,0.0002810692],"genre_scores_gemma":[0.9975446,0.0003483959,0.00009854353,0.001109625,0.0003375017,0.0001509039,0.0002033445,0.00003378726,0.0001732983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1386508,"threshold_uncertainty_score":0.7790295,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2054047572","doi":"10.4161/cbt.28180","title":"Targeting Met and Notch in the<i>Lfng</i>-deficient,<i>Met</i>-amplified triple-negative breast cancer","year":2014,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; National Institute on Aging; National Institutes of Health; Hospital for Sick Children","keywords":"Notch signaling pathway; Cancer research; Triple-negative breast cancer; Downregulation and upregulation; Biology; Carcinogenesis; Breast cancer; Cell; Cancer; Molecular biology; Cell biology; Signal transduction; Genetics; Gene","authors":[{"name":"Shubing Zhang","is_ca":false},{"name":"Wen-Cheng Chung","is_ca":false},{"name":"Lucio Miele","is_ca":false},{"name":"Keli Xu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02991940047917414,"gpt":0.3282720348353881,"spread":0.298352634356214,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007561361,0.0002833843,0.0005841816,0.0001255793,0.0001347505,0.00002422297,0.0001887625,0.0001492449,0.0004229124],"category_scores_gemma":[0.00004059775,0.000179261,0.0001097813,0.0004103921,0.0003110492,0.0000526605,0.00003483564,0.0003434758,0.000006226396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001111184,"about_ca_system_score_gemma":0.0001585981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003484597,"about_ca_topic_score_gemma":0.0003781775,"domain_scores_codex":[0.9981732,0.0002857634,0.000344346,0.0005514705,0.0001460469,0.0004992068],"domain_scores_gemma":[0.999029,0.0002488482,0.0001674329,0.0003312639,0.00011452,0.0001089099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003010728,0.0003338181,0.1605995,0.0001013681,0.0004922099,0.00001138713,0.007011232,0.00005367725,0.2538088,0.001589843,0.006306362,0.5666811],"study_design_scores_gemma":[0.03034819,0.002230437,0.2010959,0.0004350108,0.0004911723,0.0001658905,0.003836588,0.0002555194,0.03189263,0.002584429,0.7252704,0.001393853],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708523,0.01933988,0.0003698974,0.006582809,0.0008650027,0.0009173968,0.0002278877,0.00004577019,0.0007990454],"genre_scores_gemma":[0.9692447,0.01826562,0.0003383134,0.01079434,0.0006886033,0.0004042235,0.0000314137,0.00003272202,0.0002001333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.718964,"threshold_uncertainty_score":0.7310053,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2009255575","doi":"10.4161/cbt.8.7.7790","title":"RNA interference of MBD1 in BxPC-3 human pancreatic cancer cells delivered by PLGA-poloxamer nanoparticles","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pancreas Centre (Canada)","funders":"National Natural Science Foundation of China","keywords":"Pancreatic cancer; Transfection; Cancer research; Cancer cell; Chemistry; Small interfering RNA; Cell biology; Molecular biology; Cancer; Biology; Gene; Biochemistry; Genetics","authors":[{"name":"Guopei Luo","is_ca":false},{"name":"Chen Jin","is_ca":false},{"name":"Jiang Long","is_ca":false},{"name":"Deliang Fu","is_ca":false},{"name":"Feng Yang","is_ca":false},{"name":"Jin Xu","is_ca":true},{"name":"Xianjun Yu","is_ca":true},{"name":"Wei Chen","is_ca":false},{"name":"Quanxing Ni","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01813879459642114,"gpt":0.3028471632181498,"spread":0.2847083686217286,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001034583,0.0002371528,0.0003419978,0.00006297734,0.00004754981,0.000009540441,0.000372617,0.0002253527,0.0002405972],"category_scores_gemma":[0.000006505888,0.0002035989,0.000096054,0.0001198849,0.0002163043,0.000007567041,0.00003900715,0.0001217995,0.00000613912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003695368,"about_ca_system_score_gemma":0.00008694905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001180348,"about_ca_topic_score_gemma":0.0003735352,"domain_scores_codex":[0.9986403,0.0001117137,0.0003640127,0.0004532553,0.00005852354,0.0003722143],"domain_scores_gemma":[0.9993324,0.00001317809,0.0001579975,0.0003326786,0.00009775098,0.00006600759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003194977,0.0001103962,0.01143029,0.000005175794,0.00008439496,0.000001113861,0.0001776785,0.00002304366,0.9641604,0.00002506654,0.002224502,0.02143841],"study_design_scores_gemma":[0.0009792987,0.001174462,0.007178325,0.00005407161,0.00001392725,9.423072e-7,0.00007694212,0.00001307449,0.9877047,0.0002137935,0.002353278,0.0002371963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798755,0.01917344,0.00005143117,0.000250084,0.0001756756,0.0001981501,0.00009933789,0.00001095276,0.0001654095],"genre_scores_gemma":[0.9805744,0.01748194,0.00003776397,0.001383787,0.000111165,0.00007357463,0.00006220455,0.00001520792,0.0002599577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02354426,"threshold_uncertainty_score":0.8302521,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2070034939","doi":"10.4161/cbt.5.5.2553","title":"Anti-tumor effects of the bacterium caulobacter crescentus in murine tumor models","year":2006,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Caulobacter crescentus; Lewis lung carcinoma; Biology; Cancer research; Cancer; Immunology; Cell cycle; Metastasis; Genetics","authors":[{"name":"Prerak Bhatnagar","is_ca":true},{"name":"Amit Awasthi","is_ca":false},{"name":"John F. Nomellini","is_ca":false},{"name":"John Smit","is_ca":false},{"name":"M.R. Suresh","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00824562183102856,"gpt":0.2685634913437827,"spread":0.2603178695127541,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005941205,0.0001692226,0.0002215306,0.00004112494,0.00004093747,0.000007451585,0.0002477548,0.00007729534,0.00003124068],"category_scores_gemma":[0.000006742788,0.0001117451,0.0001115999,0.0001175948,0.0001825252,0.000004350815,0.00007987999,0.00009372645,0.000001805026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004840509,"about_ca_system_score_gemma":0.000135975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002868027,"about_ca_topic_score_gemma":0.00132163,"domain_scores_codex":[0.9989609,0.0001127791,0.000184663,0.0003194076,0.0000696532,0.0003525656],"domain_scores_gemma":[0.9994461,0.00001284911,0.00008769245,0.0003600589,0.0000515995,0.0000416771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002891438,0.0001685057,0.1469636,0.00002179674,0.00007509478,0.000008386859,0.00001501493,0.00005318243,0.8504148,0.00004388053,0.0004645556,0.001481994],"study_design_scores_gemma":[0.002611343,0.0003047432,0.2248089,0.00003541405,0.000007862761,0.000006608871,0.000003412912,0.00001690337,0.7610013,0.0003561144,0.01070757,0.0001397776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902911,0.008547039,0.00002570422,0.000184345,0.0002621069,0.0004408578,0.00007539111,0.000006168731,0.0001673345],"genre_scores_gemma":[0.9973081,0.001645781,0.00001864908,0.0004156372,0.0002012225,0.0001684012,0.00005724446,0.00001949855,0.0001654863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08941345,"threshold_uncertainty_score":0.4556831,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1974358843","doi":"10.4161/cbt.21346","title":"The impact of PTEN tumor suppressor gene on acquiring resistance to tamoxifen treatment in breast cancer patients","year":2012,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"PTEN; Tamoxifen; Loss of heterozygosity; Breast cancer; Cancer research; Tumor suppressor gene; Breast carcinoma; Estrogen receptor; Cancer; Oncology; Medicine; Estrogen; Internal medicine; Biology; PI3K/AKT/mTOR pathway; Gene; Carcinogenesis; Signal transduction; Allele","authors":[{"name":"Nikola Tanić","is_ca":true},{"name":"Zorka Milovanović","is_ca":false},{"name":"Nasta Tanić","is_ca":false},{"name":"Radan Džodić","is_ca":false},{"name":"Zorica D. Juranić","is_ca":false},{"name":"Sneẑana Šušnjar","is_ca":false},{"name":"Vesna Plešinac-Karapandžić","is_ca":false},{"name":"Svetislav Tatić","is_ca":false},{"name":"Tatjana Dramićanin","is_ca":false},{"name":"Radoslav Davidović","is_ca":false},{"name":"Bogomir Dimitrijević","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01703745018888738,"gpt":0.3266533564715072,"spread":0.3096159062826198,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001789681,0.0002736491,0.0002809319,0.00005289292,0.00008887152,0.00001006903,0.0003369256,0.00013495,0.00007409423],"category_scores_gemma":[0.00001430364,0.0001715113,0.0001490438,0.0001383195,0.0001472381,0.0000063228,0.00005112631,0.00007777501,0.000004163208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003753833,"about_ca_system_score_gemma":0.0001883508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000784213,"about_ca_topic_score_gemma":0.0003099025,"domain_scores_codex":[0.9985231,0.0001440254,0.0002807504,0.000379861,0.00009088884,0.0005813746],"domain_scores_gemma":[0.9990938,0.00004281514,0.0001652628,0.0004644434,0.0001100418,0.0001236001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001945307,0.000180879,0.3516454,0.000003050511,0.0002191491,3.705711e-7,0.0002413487,0.0002615778,0.6380319,0.000007701172,0.001266045,0.006197255],"study_design_scores_gemma":[0.001724539,0.0007983721,0.3774894,0.00004103493,0.00001178664,0.000001205907,0.00001325569,0.000003580362,0.603969,0.00002371981,0.0156735,0.0002505761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865409,0.01146555,0.000009224882,0.0003444712,0.0004846153,0.0004656829,0.0005880677,0.000008785177,0.00009271414],"genre_scores_gemma":[0.9950019,0.003087028,0.00003316275,0.0004799734,0.0005618351,0.0005805481,0.00004469333,0.00003842477,0.0001725019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03406293,"threshold_uncertainty_score":0.6994029,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1987077074","doi":"10.4161/cbt.10.5.12533","title":"Low density lipoprotein receptor mediates anti-VEGF effect of lymphocyte T-derived microparticles in Lewis lung carcinoma cells","year":2010,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Lewis lung carcinoma; Cancer research; Angiogenesis; Apoptosis; Vascular endothelial growth factor; Chemistry; Cancer; Biology; Medicine; Internal medicine; Metastasis; VEGF receptors; Biochemistry","authors":[{"name":"Chun Yang","is_ca":true},{"name":"Carmen Gagnon","is_ca":true},{"name":"Xin Hou","is_ca":true},{"name":"Pierre Hardy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004563629885135569,"gpt":0.249396875667691,"spread":0.2448332457825554,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003231203,0.0002619506,0.0003628905,0.00005985245,0.00005041828,0.000009566656,0.0003525087,0.0003546952,0.00007456682],"category_scores_gemma":[0.00005170538,0.0002244641,0.0001416184,0.0001176175,0.0004465767,0.000005381154,0.00009381727,0.0001739612,0.000008817335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003408577,"about_ca_system_score_gemma":0.0001580848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003499276,"about_ca_topic_score_gemma":0.0002476447,"domain_scores_codex":[0.9984642,0.0002734443,0.0003022517,0.0005023635,0.00006870399,0.0003890533],"domain_scores_gemma":[0.9990778,0.00004705346,0.0001610772,0.0005229414,0.00007638568,0.000114771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005766283,0.000157308,0.1237367,0.0000360972,0.00006162653,0.000004579485,0.00008026628,0.000004058816,0.8609155,0.000003362214,0.0001121871,0.01431163],"study_design_scores_gemma":[0.003771148,0.0003431325,0.01948657,0.00001702238,0.00001611521,0.000002901747,0.00001198896,0.00003162157,0.9752786,0.00002029249,0.0007875739,0.0002330961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875351,0.0112265,0.00003048445,0.00008204969,0.000564263,0.0004681266,0.00006655039,0.00001632073,0.00001066387],"genre_scores_gemma":[0.9967959,0.002259143,0.0002486691,0.0001691045,0.0002892312,0.0001039225,0.00007725744,0.00003684592,0.00001991229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.114363,"threshold_uncertainty_score":0.9153382,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2042219399","doi":"10.4161/cbt.5.8.2878","title":"Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-Cysteine","year":2006,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"National Cancer Institute","keywords":"DNA damage; Molecular biology; Apoptosis; Cell cycle; Biology; Phosphorylation; DNA fragmentation; Topoisomerase; Chemistry; Cell biology; Cancer research; Programmed cell death; DNA; Biochemistry","authors":[{"name":"Xuan Huang","is_ca":false},{"name":"Akira Kurose","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01116768354192013,"gpt":0.2724970602103883,"spread":0.2613293766684682,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000130265,0.0001990947,0.0002244197,0.00002093255,0.0001035505,0.0000102178,0.0001489892,0.0002378623,0.00004224108],"category_scores_gemma":[0.000003176323,0.0001568365,0.00006376644,0.0000833685,0.0001488817,0.000005736622,0.00003084278,0.00009782026,4.465787e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005099205,"about_ca_system_score_gemma":0.00005942446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001531824,"about_ca_topic_score_gemma":0.00005051454,"domain_scores_codex":[0.9989814,0.00007510648,0.0002613378,0.000370957,0.00008435956,0.0002269032],"domain_scores_gemma":[0.9993578,0.00001317609,0.0002367159,0.0002749068,0.00008126879,0.00003611274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003938488,0.00007310367,0.0001627335,0.000005613801,0.0001179038,4.134912e-8,0.00005022192,0.000001492009,0.9687617,0.00005951329,0.007248727,0.02312507],"study_design_scores_gemma":[0.00140758,0.0008152982,0.0002638983,0.000009524035,0.00001839643,0.000001473252,0.00002574928,0.00002137773,0.8714443,0.0001126663,0.1257206,0.0001591431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749449,0.02050781,0.001867675,0.001694507,0.0001733625,0.0003718947,0.0003948283,0.00001097799,0.00003405759],"genre_scores_gemma":[0.9895417,0.007243582,0.00004094596,0.001433701,0.0001456915,0.00008797096,0.0004088633,0.00002687111,0.001070675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1184719,"threshold_uncertainty_score":0.6395608,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3113123801","doi":"10.1080/15384047.2021.1902913","title":"Targeting EZH2-mediated methylation of histone 3 inhibits proliferation of pediatric acute monocytic leukemia cells <i>in vitro</i>","year":2021,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Weldon FOP Research Fund","keywords":"EZH2; PRC2; Cancer research; Histone H3; Histone methyltransferase; Cell culture; Methyltransferase; Cell growth; Leukemia; Biology; Myeloid leukemia; Epigenetics; Methylation; Immunology; Biochemistry; Genetics","authors":[{"name":"Abdulhameed Al‐Ghabkari","is_ca":true},{"name":"Aru Narendran","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01537197399373852,"gpt":0.3079283007181835,"spread":0.292556326724445,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002487903,0.0001426151,0.0002662346,0.00008611795,0.00002851238,0.000003810066,0.00009066959,0.0002589454,0.00001724464],"category_scores_gemma":[0.00004371689,0.0001397395,0.00007604893,0.0002604316,0.00006168753,0.000005324262,0.00003339729,0.00009089019,9.964806e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006604994,"about_ca_system_score_gemma":0.0003786882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000473096,"about_ca_topic_score_gemma":0.00001587984,"domain_scores_codex":[0.9987863,0.000180819,0.0004478573,0.0003241528,0.00007571327,0.0001851191],"domain_scores_gemma":[0.9991846,0.00003550756,0.0003000824,0.0001990808,0.0002451353,0.00003559651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002188509,0.00004443305,0.008147548,0.00001852361,0.00005991586,6.861426e-7,0.0001115172,0.0009380496,0.9868283,0.000009167706,0.00003403483,0.003588989],"study_design_scores_gemma":[0.001040479,0.0001773916,0.001510952,0.000005234953,0.00002577617,3.049711e-7,0.00001619536,0.000298725,0.9955595,0.000110759,0.001124772,0.0001298703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967528,0.03017937,0.001646662,0.00005694579,0.0002443298,0.0002172556,0.00007896779,0.000005710852,0.00004273036],"genre_scores_gemma":[0.9678716,0.03017328,0.0008742838,0.00009607678,0.0002197559,0.00004099278,0.0006531275,0.00001862607,0.00005228037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008731256,"threshold_uncertainty_score":0.5698412,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1980776216","doi":"10.4161/cbt.8.2.7117","title":"Preclinical assessment of anti-cancer drugs by using RP215 monoclonal antibody","year":2009,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Nuclear Power Institute of China","keywords":"Monoclonal antibody; Cancer; Ovarian cancer; Antibody; Immunohistochemistry; Epitope; Medicine; In vivo; Cancer cell; Humanized antibody; Pathology; Cancer research; Internal medicine; Immunology; Biology","authors":[{"name":"Gregory Lee","is_ca":false},{"name":"Ruiai Chu","is_ca":false},{"name":"Hong Hoi Ting","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08980680288788907,"gpt":0.5037057564335296,"spread":0.4138989535456405,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000310565,0.0002453508,0.0006820654,0.00009686674,0.00009757653,0.000009127075,0.0002222896,0.0002326828,0.001152814],"category_scores_gemma":[0.00001064526,0.0001764102,0.00022966,0.0002003509,0.0003942238,0.00005233459,0.00003870521,0.0004019309,0.000004385519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001091451,"about_ca_system_score_gemma":0.0004903779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004920582,"about_ca_topic_score_gemma":0.000003346779,"domain_scores_codex":[0.9981665,0.0001420528,0.00048139,0.0004569007,0.0002684316,0.0004847028],"domain_scores_gemma":[0.9990453,0.0001172941,0.0001790616,0.0002782594,0.0001948924,0.0001852613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005564927,0.0003176534,0.3121989,0.00002260577,0.0002476629,0.000002915893,0.00007129493,0.00000987717,0.6361375,0.0001950584,0.00103526,0.0492048],"study_design_scores_gemma":[0.007910578,0.003961745,0.6058782,0.0003459455,0.0001312899,0.00003341566,0.00007314201,0.003008514,0.221386,0.001035847,0.1554865,0.0007488435],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778449,0.01511749,0.0001427824,0.005268297,0.0002694038,0.0003919663,0.0002154717,0.00003051013,0.0007191875],"genre_scores_gemma":[0.9611753,0.03320334,0.0008887988,0.003107446,0.0005330223,0.00002592521,0.0001451256,0.00002039167,0.0009006966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4147515,"threshold_uncertainty_score":0.9997603,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1969367341","doi":"10.4161/cbt.3.11.1309","title":"siRNAs: Mechanism of RNA interference, In vivo and potential clinical applications","year":2004,"lang":"en","type":"review","venue":"Cancer Biology & Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Simon Fraser University","keywords":"RNA interference; Small interfering RNA; Gene silencing; Trans-acting siRNA; Functional genomics; RNA silencing; Computational biology; RNA; Biology; RNA-induced transcriptional silencing; DNA-directed RNA interference; RNA-induced silencing complex; microRNA; Cell biology; Genetics; Gene; Genomics; Genome","authors":[{"name":"Tom C. Karagiannis","is_ca":false},{"name":"Assam El‐Osta","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04936837489902211,"gpt":0.387817453968767,"spread":0.3384490790697449,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002017317,0.0002994791,0.0009254478,0.0001097001,0.0000268341,0.000007926431,0.0003954292,0.0007558386,0.00006626363],"category_scores_gemma":[0.000008412148,0.0002376254,0.0003003167,0.0001059116,0.0002646789,0.000002444711,0.0001169552,0.0002515396,0.00000442748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002505927,"about_ca_system_score_gemma":0.0004001517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006326003,"about_ca_topic_score_gemma":0.00004144232,"domain_scores_codex":[0.9983022,0.0001708862,0.0006748453,0.0005937559,0.00003600026,0.0002223231],"domain_scores_gemma":[0.9991251,0.00002213856,0.0003344669,0.0003874873,0.00007101503,0.00005980399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006859598,0.00007892647,0.00005632184,0.000502034,0.0003361712,0.000001642228,0.00001557657,8.816955e-7,0.00870032,0.0005629753,0.00009444832,0.9895821],"study_design_scores_gemma":[0.001014369,0.001135443,0.00001611534,0.002088983,0.0001514208,0.0000213097,0.00002353682,9.738372e-7,0.004985101,0.002232445,0.9878173,0.0005129389],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004090703,0.9932255,0.001491755,0.00001761183,0.0003317047,0.0005804474,0.0001599835,0.000006195457,0.00009613145],"genre_scores_gemma":[0.01101607,0.987718,0.00009973547,0.0001318411,0.0003489913,0.0004009654,0.0001258744,0.00002691292,0.0001315378],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9890692,"threshold_uncertainty_score":0.9690083,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2006951838","doi":"10.4161/cbt.7.4.5533","title":"Differential sensitivity of A549 non small lung carcinoma cell responses to epidermal growth factor receptor pathway inhibitors","year":2008,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Epidermal growth factor receptor; A549 cell; Motility; Epidermal growth factor; Cancer research; Cell growth; Biology; EGFR inhibitors; Cell biology; Growth factor receptor; Apoptosis; Cell; Receptor; Signal transduction; Biochemistry","authors":[{"name":"María Jaramillo","is_ca":true},{"name":"M. Banville","is_ca":false},{"name":"Catherine Collins","is_ca":false},{"name":"Béatrice Paul‐Roc","is_ca":false},{"name":"Lucie Bourget","is_ca":false},{"name":"Maureen D. O'Connor‐McCourt","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0625310769672316,"gpt":0.3354780181004788,"spread":0.2729469411332472,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003353611,0.0003370968,0.0007589652,0.0002759689,0.0001369514,0.000006478565,0.0001869602,0.0003309967,0.000910671],"category_scores_gemma":[0.0001326315,0.0002718132,0.0002207024,0.00033332,0.0004414446,0.00003920233,0.00009738747,0.0004637111,0.00003300455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003539353,"about_ca_system_score_gemma":0.0009585162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002130975,"about_ca_topic_score_gemma":0.0001076867,"domain_scores_codex":[0.9972721,0.0006772893,0.0004576823,0.0006367418,0.0002595228,0.0006966314],"domain_scores_gemma":[0.9982113,0.0004295506,0.0001478189,0.0004970303,0.0003562637,0.0003580451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002376026,0.0001240708,0.3911716,0.00007498274,0.00006284965,0.0000561274,0.001026106,4.954689e-7,0.5975764,0.000003467916,0.001576053,0.005951887],"study_design_scores_gemma":[0.00180078,0.001008119,0.303318,0.00007018371,0.00001154335,0.00002554613,0.0000446207,0.0000211558,0.6896315,0.000004236246,0.003858305,0.0002060204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938462,0.001659275,0.0002870669,0.001670264,0.000942137,0.001026926,0.0003655739,0.00005815742,0.0001443446],"genre_scores_gemma":[0.9948725,0.002010307,0.0002331715,0.0008768503,0.0009959275,0.0001558756,0.00004074247,0.00006301012,0.0007515952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09205515,"threshold_uncertainty_score":0.9999734,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029597892","doi":"10.4161/cbt.24596","title":"Identification of repurposed small molecule drugs for chordoma therapy","year":2013,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Bone Tumor Diagnosis and Treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; Medical Center, University of Pittsburgh; National Institutes of Health; University of Calgary","keywords":"Chordoma; Staurosporine; Pharmacology; Medicine; Cancer research; Internal medicine; Biology; Pathology","authors":[{"name":"Menghang Xia","is_ca":false},{"name":"Ruili Huang","is_ca":false},{"name":"Srilatha Sakamuru","is_ca":false},{"name":"David A. Alcorta","is_ca":false},{"name":"Ming-Hsuang Cho","is_ca":false},{"name":"Dae‐Hee Lee","is_ca":false},{"name":"Deric M. Park","is_ca":false},{"name":"Michael J. Kelley","is_ca":false},{"name":"Josh Sommer","is_ca":false},{"name":"Christopher P. Austin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03344090278317161,"gpt":0.32340432743414,"spread":0.2899634246509684,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009813105,0.0001350512,0.0003038081,0.00005694782,0.00004341049,0.000007214897,0.00008885287,0.00009519471,0.0002756265],"category_scores_gemma":[0.000009681139,0.00009571741,0.0001338266,0.00009210249,0.00009995867,0.0000290425,0.000006372376,0.00005057561,0.00001619796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004342595,"about_ca_system_score_gemma":0.0000615188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003191131,"about_ca_topic_score_gemma":0.000006363449,"domain_scores_codex":[0.999168,0.00003709267,0.0002879905,0.0002714149,0.00004683754,0.0001886005],"domain_scores_gemma":[0.9991962,0.00006059564,0.000180425,0.0003167213,0.00019067,0.00005539151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004835972,0.0004603901,0.05649221,0.00001654506,0.0004349644,7.111256e-7,0.0003899035,4.340217e-7,0.7337213,0.0003145025,0.001108921,0.2065766],"study_design_scores_gemma":[0.008904143,0.001410646,0.196378,0.0000400247,0.00005090086,0.000003419517,0.0000760096,0.00004470359,0.7787479,0.001506795,0.01267325,0.0001641828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838163,0.01215069,0.00008576917,0.00201329,0.0002002029,0.001558032,0.00003067376,0.00003377951,0.0001112582],"genre_scores_gemma":[0.986967,0.008958693,0.0001795121,0.001141853,0.0001073752,0.001917048,0.00007183783,0.0000251177,0.0006316061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2064124,"threshold_uncertainty_score":0.3903243,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2059213057","doi":"10.4161/cbt.25087","title":"In vitro targeting of Polo-like kinase 1 in bladder carcinoma","year":2013,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pediatric Oncology Group","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"PLK1; Doxorubicin; Cisplatin; Bladder cancer; Cancer research; Radiosensitivity; Polo-like kinase; Methotrexate; Growth inhibition; Medicine; Chemotherapy; Pharmacology; Cancer; Apoptosis; Oncology; Biology; Radiation therapy; Cell cycle; Internal medicine","authors":[{"name":"María Sol Brassesco","is_ca":true},{"name":"Julia Alejandra Pezuk","is_ca":false},{"name":"Andressa Gois Morales","is_ca":false},{"name":"Jaqueline Carvalho de Oliveira","is_ca":false},{"name":"Gabriela Molinari Roberto","is_ca":true},{"name":"Glenda Nicioli da Silva","is_ca":false},{"name":"Harley Francisco de Oliveira","is_ca":false},{"name":"Carlos Alberto Scrideli","is_ca":true},{"name":"Luíz Gonzaga Tone","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008946025476519496,"gpt":0.2593464702345232,"spread":0.2504004447580037,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009939652,0.0001416885,0.0002016471,0.00007505587,0.0000166231,0.000003858237,0.0001793666,0.0002273842,0.0001416369],"category_scores_gemma":[0.000009135237,0.000125535,0.00006194599,0.00009727006,0.0001148391,0.000004286599,0.00004811061,0.0001056015,0.000005018044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002408854,"about_ca_system_score_gemma":0.00007756279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001777158,"about_ca_topic_score_gemma":0.0002038463,"domain_scores_codex":[0.999055,0.0000817766,0.0002476834,0.0002980769,0.00002701316,0.0002903939],"domain_scores_gemma":[0.9996101,0.00001042482,0.00007977748,0.0002147413,0.00004948658,0.00003550186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001133699,0.00005266805,0.05893523,0.000004926732,0.00002392801,0.000001195656,0.0001031277,0.000009572037,0.9358606,0.00001434127,0.0008772251,0.004003866],"study_design_scores_gemma":[0.001248844,0.0001597315,0.02209241,0.000006504251,0.000002773044,0.000001748695,0.00009640882,0.00005064995,0.9615939,0.0001389619,0.01442623,0.0001817829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887699,0.01029338,0.00004188774,0.0003085195,0.00021393,0.0002510546,0.0000246784,0.000003580089,0.00009304612],"genre_scores_gemma":[0.9948268,0.003135495,0.0002253112,0.001317651,0.0001317731,0.0001286831,0.00008832738,0.00001722046,0.0001287193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03684281,"threshold_uncertainty_score":0.5119171,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2063081197","doi":"10.4161/cbt.12.11.18366","title":"New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort","year":2011,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto Public Health; Public Health Ontario; Hospital for Sick Children; University of Toronto; University Health Network; Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"National Cancer Institute; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Prostate cancer; Medicine; Oncology; Prostate; Internal medicine; Single-nucleotide polymorphism; Cancer; Prostate biopsy; Cohort; Nomogram; Prostate cancer screening; Odds ratio; SNP; Prostate-specific antigen; Genotype; Biology; Gene; Genetics","authors":[{"name":"Robert K. Nam","is_ca":true},{"name":"William Zhang","is_ca":true},{"name":"Katherine Siminovitch","is_ca":true},{"name":"Adam Shlien","is_ca":true},{"name":"Michael W. Kattan","is_ca":true},{"name":"Laurence Klotz","is_ca":true},{"name":"John Trachtenberg","is_ca":true},{"name":"Yan Lu","is_ca":true},{"name":"Jinyi Zhang","is_ca":true},{"name":"Changhong Yu","is_ca":true},{"name":"Ants Toi","is_ca":true},{"name":"D.A. Loblaw","is_ca":true},{"name":"Vasundara Venkateswaran","is_ca":true},{"name":"Aleksandra Stanimirovic","is_ca":true},{"name":"Linda Sugar","is_ca":true},{"name":"David Malkin","is_ca":true},{"name":"Arun Seth","is_ca":true},{"name":"Steven A. Narod","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02873317384404985,"gpt":0.2843946574716115,"spread":0.2556614836275616,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002579909,0.0003807979,0.0007767362,0.0001280201,0.0001312406,0.00002352585,0.00009714827,0.000196996,0.000412167],"category_scores_gemma":[0.00006635738,0.0002745149,0.0000562395,0.0003347148,0.00008757161,0.000104321,0.00005642948,0.0002463839,0.000004112384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001369057,"about_ca_system_score_gemma":0.0003518001,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01370839,"about_ca_topic_score_gemma":0.00828843,"domain_scores_codex":[0.9978709,0.0001934793,0.0003854213,0.000791231,0.0001941544,0.0005648162],"domain_scores_gemma":[0.9983459,0.0001643872,0.0008041391,0.0002718949,0.0002064444,0.0002073101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002883576,0.0004393872,0.9724582,0.000006902305,0.002547316,0.0002346237,0.008428893,0.000006489418,0.0006696242,8.719107e-7,0.0001647339,0.01215934],"study_design_scores_gemma":[0.0129156,0.001662397,0.9826258,0.0004917078,0.0002989517,0.000002786579,0.0004628966,0.000009631573,0.0008260135,0.00008773171,0.0003160347,0.0003004846],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770109,0.01804456,0.00001216075,0.001065812,0.0001692146,0.002898154,0.0006808412,0.00006546659,0.00005289986],"genre_scores_gemma":[0.9781884,0.01787058,0.0001676805,0.001044724,0.0001009226,0.001819683,0.0002040302,0.00005792206,0.0005460352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01185886,"threshold_uncertainty_score":0.9999707,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1990386747","doi":"10.4161/cbt.6.8.4504","title":"Breast cancer metastasis in a human bone NOD/SCID mouse model","year":2007,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Nod; Breast cancer; Bone metastasis; Metastasis; Cancer research; Cancer; Medicine; Tumor microenvironment; Bone marrow; CA15-3; Pathology; Oncology; Immunology; Internal medicine; Endocrinology","authors":[{"name":"Wenyi Yang","is_ca":true},{"name":"Pearl Lam","is_ca":false},{"name":"A. Richard Kitching","is_ca":false},{"name":"Harriette Kahn","is_ca":false},{"name":"Albert Yee","is_ca":false},{"name":"Jane E. Aubin","is_ca":false},{"name":"Arun Seth","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04545125386305489,"gpt":0.3628364712855482,"spread":0.3173852174224933,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005263052,0.0003191795,0.0007128666,0.0003020423,0.00009519319,0.00001082781,0.0001637428,0.0002147213,0.001216457],"category_scores_gemma":[0.000003759489,0.0002555082,0.0002074028,0.0004024918,0.0002396871,0.00006695339,0.00003880514,0.0003493724,0.000009196506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004283435,"about_ca_system_score_gemma":0.000306838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004942377,"about_ca_topic_score_gemma":0.004380317,"domain_scores_codex":[0.9980252,0.00005139147,0.0004763582,0.0005779752,0.0001560086,0.0007130359],"domain_scores_gemma":[0.9990131,0.00003060781,0.0001480141,0.000448555,0.0001307844,0.0002289745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001718165,0.0003311943,0.03733044,0.00003828411,0.0003647147,0.00002990171,0.0006200583,0.0001346246,0.6677805,0.0003079025,0.001457903,0.2898863],"study_design_scores_gemma":[0.03504461,0.001289863,0.07283244,0.0004166814,0.0007068043,0.0002889004,0.0007256531,0.0006922443,0.7369308,0.001352674,0.1474909,0.002228326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757115,0.01935821,0.0005845908,0.002293587,0.0003094988,0.0005342604,0.0004302402,0.00007786662,0.0007002674],"genre_scores_gemma":[0.9766738,0.01560409,0.0005760323,0.004580276,0.0004962771,0.0002291627,0.00005141431,0.00006414862,0.00172475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.287658,"threshold_uncertainty_score":0.9999897,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2009996790","doi":"10.4161/cbt.3.2.622","title":"Pharmacodynamic Behavior of Liposomal Antisense Oligonucleotides Targeting Her-2/neu and Vascular Endothelial Growth Factor in an Ascitic MDA435/LCC6 Human Breast Cancer Model","year":2004,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"University of the Pacific; Georgetown University","keywords":"Liposome; Pharmacokinetics; Pharmacodynamics; Pharmacology; Cancer research; Ascites; Distribution (mathematics); Medicine; Chemistry; Internal medicine; Biochemistry","authors":[{"name":"Dawn Waterhouse","is_ca":true},{"name":"Wieslawa H. Dragowska","is_ca":false},{"name":"Karen A. Gelmon","is_ca":false},{"name":"Lawrence D. Mayer","is_ca":false},{"name":"Marcel B. Bally","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0359185773925861,"gpt":0.3696789308987723,"spread":0.3337603535061862,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001326016,0.0002737777,0.0005316984,0.0001840624,0.0001225765,0.00001218834,0.0001668136,0.0001536575,0.0002472579],"category_scores_gemma":[0.000006313111,0.000213941,0.0001307536,0.0001542388,0.0004779742,0.0001066142,0.00004865431,0.0003461648,0.000001768259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001345532,"about_ca_system_score_gemma":0.0002425326,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008206904,"about_ca_topic_score_gemma":0.0008184432,"domain_scores_codex":[0.9983711,0.0001032945,0.0003627236,0.0004656723,0.0001840136,0.0005131529],"domain_scores_gemma":[0.9993393,0.00003902338,0.00009662273,0.0001664564,0.0001585105,0.0002001022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003996505,0.0002136005,0.368204,0.00005392446,0.0001018049,0.00002571323,0.0003801132,0.00009293387,0.6251705,0.0001600072,0.000003176405,0.005194574],"study_design_scores_gemma":[0.00867518,0.0008691441,0.8486786,0.0002407314,0.0001069489,0.00006987146,0.00009343618,0.001388176,0.1386684,0.0006160617,0.0001174453,0.0004759679],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993347,0.004584086,0.00001442614,0.0006330037,0.0001264281,0.0005009256,0.0007390383,0.00003362669,0.00002149718],"genre_scores_gemma":[0.9859061,0.01291491,0.0001802588,0.0004732363,0.0002716436,0.0001200321,0.00005598145,0.00004226693,0.00003556965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4865022,"threshold_uncertainty_score":0.9983975,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1983277776","doi":"10.4161/cbt.25327","title":"Dual kinin B1 and B2 receptor activation provides enhanced blood–brain barrier permeability and anticancer drug delivery into brain tumors","year":2013,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Carboplatin; Kinin; Blood–brain barrier; Pharmacology; Glioma; Agonist; Brain tumor; Medicine; Drug delivery; Bradykinin; Cancer research; Bioavailability; Chemistry; Receptor; Chemotherapy; Cisplatin; Internal medicine; Pathology; Central nervous system","authors":[{"name":"Jérôme Côté","is_ca":true},{"name":"Martin Savard","is_ca":true},{"name":"Witold Neugebauer","is_ca":true},{"name":"David Fortin","is_ca":true},{"name":"Martin Lepage","is_ca":true},{"name":"Fernand Gobeil","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01284291113800464,"gpt":0.2794160027067111,"spread":0.2665730915687065,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002997171,0.0002725816,0.0004458657,0.0000914316,0.0001911467,0.00003396907,0.00006972502,0.0001750981,0.0009350316],"category_scores_gemma":[0.000152038,0.0002161692,0.00006938383,0.0001489307,0.0006412696,0.000233788,0.00003917095,0.0001720619,0.000006838926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008133331,"about_ca_system_score_gemma":0.000239574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001929872,"about_ca_topic_score_gemma":0.0001565682,"domain_scores_codex":[0.9984329,0.000156244,0.0003393162,0.0005945011,0.0001103403,0.0003666584],"domain_scores_gemma":[0.99887,0.0003575924,0.0001454232,0.0002543314,0.0001742281,0.0001983981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003271993,0.00007060562,0.2492515,0.00004524824,0.0001331792,4.987771e-7,0.003471636,5.615192e-7,0.635721,0.00008527802,0.00142627,0.1094669],"study_design_scores_gemma":[0.004510648,0.0008289402,0.6474829,0.0002036536,0.00005144112,0.000007709318,0.000750176,0.0001539797,0.3323604,0.002698567,0.01047373,0.0004778325],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980396,0.00611115,0.00003752344,0.01222758,0.0001932281,0.0008943115,0.00001916666,0.00007991821,0.0000411603],"genre_scores_gemma":[0.9914367,0.001938014,0.0002911512,0.004878428,0.0004584484,0.0002849574,0.00005817663,0.00003194429,0.0006221337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3982314,"threshold_uncertainty_score":0.9999782,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2005251971","doi":"10.4161/cbt.11.6.14376","title":"Detection of<i>ERG</i>gene rearrangements and<i>PTEN</i>deletions in unsuspected prostate cancer of the transition zone","year":2011,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"PTEN; Erg; Biology; Cancer research; Prostate cancer; Cancer; Fluorescence in situ hybridization; Gene; Pathology; Medicine; Genetics; PI3K/AKT/mTOR pathway; Chromosome; Apoptosis","authors":[{"name":"Shuhong Liu","is_ca":true},{"name":"Maisa Yoshimoto","is_ca":false},{"name":"Kiril Trpkov","is_ca":false},{"name":"Qiuli Duan","is_ca":false},{"name":"Matthew Firszt","is_ca":false},{"name":"Jacques Corcos","is_ca":false},{"name":"Jeremy A. Squire","is_ca":false},{"name":"Tarek A. Bismar","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04186066725822844,"gpt":0.315915244206479,"spread":0.2740545769482505,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001167426,0.0001102426,0.0002413116,0.0001068284,0.00004939614,0.000001429053,0.00006496211,0.00009184842,0.0001348759],"category_scores_gemma":[0.000003747985,0.00006838873,0.00005888827,0.000352339,0.0003105616,0.00003208399,0.00001257938,0.0001338076,4.88979e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000972425,"about_ca_system_score_gemma":0.0001362214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002439885,"about_ca_topic_score_gemma":0.0007478849,"domain_scores_codex":[0.9992103,0.00009081975,0.0002196886,0.0002023378,0.00008524599,0.0001915842],"domain_scores_gemma":[0.9995399,0.00001381179,0.00009669813,0.0001753656,0.0001351785,0.0000391192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002314365,0.0001680819,0.09663358,0.00004214882,0.0001931496,0.000001977228,0.003269132,0.000002990546,0.8461633,0.0000198119,0.00001642628,0.05117505],"study_design_scores_gemma":[0.004792279,0.0005764239,0.3139111,0.0001399893,0.00005411904,0.000004171696,0.0002032758,0.00002776395,0.6791375,0.0002265103,0.0008434607,0.00008347245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859875,0.01194203,0.00005626399,0.0008011496,0.0001877886,0.0007825837,0.00008854475,0.00001457483,0.0001395926],"genre_scores_gemma":[0.9646118,0.03468782,0.00004301908,0.0001510165,0.00004419586,0.0002916842,0.0000167976,0.0000128838,0.0001407476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2172775,"threshold_uncertainty_score":0.3688392,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2035994750","doi":"10.4161/cbt.3.8.963","title":"Morbidity in immunosuppressed (SCID/NOD) mice treated with reovirus (Dearing 3) as an anti-cancer biotherapeutic","year":2004,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary; Calgary Laboratory Services","funders":"Calgary Laboratory Services","keywords":"Oncolytic virus; Medicine; Cancer; Nod; Pathology; Vasculitis; Humanized mouse; Immunology; Cancer research; Virus; Internal medicine; Immune system; Endocrinology","authors":[{"name":"Steve D. Loken","is_ca":true},{"name":"Kara L. Norman","is_ca":false},{"name":"Kensuke Hirasawa","is_ca":false},{"name":"Michael J. Nodwell","is_ca":false},{"name":"Wanda M. Lester","is_ca":false},{"name":"Douglas J. Demetrick","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03415273895509223,"gpt":0.3520636166960759,"spread":0.3179108777409836,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002898416,0.00040686,0.0004003562,0.0001628808,0.0001512663,0.00004020312,0.0006128816,0.0003409515,0.0002731755],"category_scores_gemma":[0.000007034584,0.0003305838,0.00008766635,0.0003775959,0.0004363355,0.00001802455,0.00005908466,0.0003200789,0.00001693045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001554732,"about_ca_system_score_gemma":0.0005377494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005532937,"about_ca_topic_score_gemma":0.004621611,"domain_scores_codex":[0.9976135,0.0002895587,0.0002984118,0.0009062469,0.0001502877,0.0007419252],"domain_scores_gemma":[0.9988363,0.00001638755,0.0001265994,0.0007459735,0.0001336003,0.0001410773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008793828,0.0002895453,0.03335689,0.000007936984,0.0002959773,0.00001008872,0.0001330399,0.0006033361,0.9467097,0.00001587683,0.00001425191,0.009769561],"study_design_scores_gemma":[0.006110975,0.006992678,0.01323464,0.00003712216,0.00001336414,0.00001021315,0.00004574779,0.00001302629,0.9692472,0.0001367809,0.003696588,0.0004616351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98265,0.01588796,0.00004822922,0.0004544638,0.0001250694,0.0006023718,0.00006785321,0.00005156711,0.0001124633],"genre_scores_gemma":[0.9750389,0.02217194,0.00009149257,0.001686299,0.0002723581,0.0003304931,0.0001370271,0.00009094423,0.0001805612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02253756,"threshold_uncertainty_score":0.9999146,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2077860295","doi":"10.4161/cbt.29687","title":"Impact of<i>ERBB2</i>mutations on in vitro sensitivity of bladder cancer to lapatinib","year":2014,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Genome British Columbia","funders":"","keywords":"Lapatinib; Cancer research; Biology; Gene; Mutation; Tyrosine-kinase inhibitor; Cell growth; Cancer; Cell culture; Tyrosine kinase; Receptor tyrosine kinase; Signal transduction; Genetics; Breast cancer; Trastuzumab","authors":[{"name":"Michela de Martino","is_ca":false},{"name":"Dazhong Zhuang","is_ca":false},{"name":"Tobias Klatte","is_ca":false},{"name":"Malte Rieken","is_ca":false},{"name":"Morgan Rouprêt","is_ca":false},{"name":"Évanguelos Xylinas","is_ca":false},{"name":"Thomas Clozel","is_ca":false},{"name":"Martin Krzywinski","is_ca":true},{"name":"Olivier Elemento","is_ca":false},{"name":"Shahrokh F. Shariat","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02429787946999678,"gpt":0.4055847812751147,"spread":0.3812869018051179,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001275388,0.0001359165,0.0003852871,0.0001429301,0.00002595247,0.000001824814,0.00003982093,0.00008018721,0.000278149],"category_scores_gemma":[0.00003147286,0.00009563181,0.0001166131,0.0002449583,0.00009584762,0.00002189644,0.000007847923,0.00008610437,0.000005456187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001971618,"about_ca_system_score_gemma":0.0003100094,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007893587,"about_ca_topic_score_gemma":0.0007764272,"domain_scores_codex":[0.9991918,0.0001123212,0.0002191339,0.0002186511,0.00006774965,0.0001903325],"domain_scores_gemma":[0.999301,0.0001609672,0.0001077342,0.0002168278,0.0001368604,0.00007657459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001387,0.000376284,0.2316067,0.00001355037,0.0006448895,0.00000209069,0.001365646,0.0008245568,0.6359357,0.0001855732,0.0003744241,0.1272836],"study_design_scores_gemma":[0.004205682,0.001690647,0.8556863,0.00009888291,0.000101073,0.000002609825,0.00005141537,0.0001377611,0.135923,0.0002601046,0.001696209,0.0001463491],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962423,0.0005985182,0.0001652855,0.001263893,0.0001860643,0.0004552964,0.000319708,0.0000150729,0.0007538517],"genre_scores_gemma":[0.99784,0.0004080542,0.0002583099,0.001031355,0.0001225092,0.0001858085,0.00006186579,0.00001650055,0.00007553399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6240796,"threshold_uncertainty_score":0.998713,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}