{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":55,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":55,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"dd30de9829c9","filters":{"venue":"Clinical and Translational Medicine"}},"results":[{"id":"W2799710201","doi":"10.1186/s40169-018-0185-6","title":"Analyses of repeated failures in cancer therapy for solid tumors: poor tumor‐selective drug delivery, low therapeutic efficacy and unsustainable costs","year":2018,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":486,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Aging","funders":"National Eye Institute; National Institutes of Health; Ministry of Education, Culture, Sports, Science and Technology; National Cancer Institute; University of Pennsylvania","keywords":"Medicine; Cancer; Drug; Drug delivery; Cancer therapy; Oncology; Intensive care medicine; Pharmacology; Internal medicine; Nanotechnology","authors":[{"name":"Hiroshi Maeda","is_ca":false},{"name":"Mahin Khatami","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09298064257482087,"gpt":0.4585024538825066,"spread":0.3655218113076857,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006856427,0.0001846136,0.0006876187,0.0001784903,0.00008031937,0.000005505756,0.00007254165,0.00008207396,0.0001391503],"category_scores_gemma":[0.0002147591,0.0001306433,0.00007674927,0.0003379545,0.001162919,0.00007084618,0.000008514715,0.000199685,5.854968e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002918886,"about_ca_system_score_gemma":0.0002700932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005452676,"about_ca_topic_score_gemma":0.0001618436,"domain_scores_codex":[0.9981711,0.0001159606,0.0008153885,0.0003998081,0.0002547697,0.0002430094],"domain_scores_gemma":[0.9977586,0.001208077,0.0001840467,0.0001629255,0.0005302484,0.000156078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06003291,0.003179424,0.6037823,0.001028863,0.002457601,0.00007301687,0.005713608,0.00007739078,0.08653134,0.002866404,0.005901499,0.2283557],"study_design_scores_gemma":[0.05644977,0.006131914,0.8806061,0.002322461,0.0003857368,0.00003722227,0.0005166595,0.002869726,0.03167502,0.01455642,0.004077214,0.0003717659],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721605,0.008991299,0.0003830713,0.01702773,0.0001114141,0.001045357,0.0000337355,0.00002618618,0.0002206723],"genre_scores_gemma":[0.9947361,0.001735145,0.0003648219,0.002335361,0.0005998434,0.00008627507,0.00003505901,0.00002098195,0.00008637501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2768238,"threshold_uncertainty_score":0.5327481,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2507486366","doi":"10.1186/s40169-016-0117-2","title":"JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers","year":2016,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"Cancer Research UK; National Heart, Lung, and Blood Institute; Celgene","keywords":"Medicine; Idiopathic pulmonary fibrosis; Bronchoalveolar lavage; Lung; Pulmonary function testing; Interstitial lung disease; Adverse effect; Pulmonary fibrosis; Internal medicine; Fibrosis; Gastroenterology","authors":[{"name":"Jos van der Velden","is_ca":false},{"name":"Ying Ye","is_ca":false},{"name":"James D. Nolin","is_ca":false},{"name":"Sidra M. Hoffman","is_ca":false},{"name":"David G. Chapman","is_ca":false},{"name":"Karolyn G. Lahue","is_ca":false},{"name":"Sarah Abdalla","is_ca":false},{"name":"Peng Chen","is_ca":false},{"name":"Yong Liu","is_ca":false},{"name":"Brydon L. Bennett","is_ca":false},{"name":"Nasreen Khalil","is_ca":true},{"name":"Donna Sutherland","is_ca":false},{"name":"William E. Smith","is_ca":false},{"name":"Gerald Horan","is_ca":false},{"name":"Mahmoud Assaf","is_ca":false},{"name":"Zebulun D. Horowitz","is_ca":false},{"name":"Rajesh Chopra","is_ca":false},{"name":"Randall M. Stevens","is_ca":false},{"name":"Maria Palmisano","is_ca":false},{"name":"Yvonne Janssen‐Heininger","is_ca":false},{"name":"Peter Schäfer","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02864083617757809,"gpt":0.3183280398796599,"spread":0.2896872037020818,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004942731,0.0001548268,0.0003825623,0.00007955966,0.00009389659,0.00000629704,0.00002881126,0.0001331479,0.000129256],"category_scores_gemma":[0.0001470276,0.00009119547,0.00009253473,0.00007596478,0.000538535,0.000132985,0.00001544967,0.0001468101,0.000005884336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001053498,"about_ca_system_score_gemma":0.00006030373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009092217,"about_ca_topic_score_gemma":5.136322e-7,"domain_scores_codex":[0.9984742,0.00007924441,0.0006364211,0.0003755021,0.0002624274,0.0001722508],"domain_scores_gemma":[0.99893,0.0004744005,0.00007927895,0.0001121478,0.00009810713,0.0003060549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03599142,0.0007414384,0.3461743,0.004159235,0.0005664298,0.0007212038,0.0004770078,0.00001072961,0.08318847,0.008472556,0.003149829,0.5163473],"study_design_scores_gemma":[0.02144137,0.009706329,0.8516536,0.05172929,0.002669651,0.004800816,0.0008606317,0.02993926,0.0002517544,0.02200431,0.003723298,0.001219689],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9588987,0.007847041,0.00226918,0.02787582,0.0003780558,0.0004402816,0.00004179926,0.00006319668,0.002185927],"genre_scores_gemma":[0.9957384,0.002122045,0.0002502243,0.0004751848,0.001026091,0.00001092193,0.00004452621,0.00001581849,0.0003167368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5151277,"threshold_uncertainty_score":0.3718843,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4313381237","doi":"10.1002/ctm2.1155","title":"Multiplex immunofluorescence and single‐cell transcriptomic profiling reveal the spatial cell interaction networks in the non‐small cell lung cancer microenvironment","year":2023,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Natural Science Foundation of China","keywords":"CD20; Stromal cell; CD38; CD8; Tumor microenvironment; FOXP3; Biology; Cancer research; Cancer cell; Lung cancer; Immune system; Pathology; Immunology; Medicine; CD34; Cancer; Stem cell; Immunohistochemistry; Cell biology","authors":[{"name":"Haoxin Peng","is_ca":false},{"name":"Xiangrong Wu","is_ca":false},{"name":"Shaopeng Liu","is_ca":true},{"name":"Miao He","is_ca":false},{"name":"Chao Xie","is_ca":false},{"name":"Ran Zhong","is_ca":false},{"name":"Jun Liu","is_ca":false},{"name":"Chenshuo Tang","is_ca":false},{"name":"Caichen Li","is_ca":false},{"name":"Shan Xiong","is_ca":false},{"name":"Hongbo Zheng","is_ca":false},{"name":"Jianxing He","is_ca":false},{"name":"Xu Lu","is_ca":true},{"name":"Wenhua Liang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03164436370602229,"gpt":0.2919426508925225,"spread":0.2602982871865002,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006120204,0.0001755,0.0001990803,0.00003131945,0.0001351176,0.00001826489,0.0001614991,0.0001529774,0.00001095297],"category_scores_gemma":[0.00001673062,0.0001079692,0.00007557746,0.0000963823,0.0003291828,0.000006758649,0.00001918989,0.0003634148,0.000001070423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005484504,"about_ca_system_score_gemma":0.00003016334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001917376,"about_ca_topic_score_gemma":0.0002618138,"domain_scores_codex":[0.998616,0.0001563493,0.0004938713,0.0003689464,0.000142856,0.0002220116],"domain_scores_gemma":[0.9994257,0.0002498798,0.00008288989,0.0001567607,0.00002230959,0.00006244428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006637661,0.0003055485,0.2215315,0.0001629805,0.00003601849,0.000008148769,0.001354362,0.00163839,0.7627545,0.000005405966,0.0004519547,0.01108743],"study_design_scores_gemma":[0.01344793,0.00146862,0.7879993,0.0004428631,0.0004235699,0.00002175265,0.001405993,0.1214483,0.06524174,0.0001270213,0.007230429,0.0007424954],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875788,0.004909122,0.003910247,0.002457,0.0004719366,0.0005029012,0.000016624,0.000007955139,0.0001454165],"genre_scores_gemma":[0.9938594,0.004305478,0.0001579576,0.0007193063,0.0006383017,0.00004027519,0.0001445436,0.00001725423,0.0001175397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6975127,"threshold_uncertainty_score":0.4402858,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3165560299","doi":"10.1002/ctm2.392","title":"A novel RANKL‐targeted flavonoid glycoside prevents osteoporosis through inhibiting NFATc1 and reactive oxygen species","year":2021,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"Science and Technology Planning Project of Guangdong Province; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"RANKL; Chemistry; Reactive oxygen species; Osteoclast; Bone resorption; Western blot; Viability assay; Biochemistry; Cell biology; Pharmacology; Internal medicine; Activator (genetics); In vitro; Receptor; Biology; Medicine","authors":[{"name":"Guoju Hong","is_ca":true},{"name":"Zhenqiu Chen","is_ca":false},{"name":"Xiaorui Han","is_ca":false},{"name":"Lin Zhou","is_ca":false},{"name":"Fengxiang Pang","is_ca":false},{"name":"Rishana Wu","is_ca":false},{"name":"Ying-Shan Shen","is_ca":false},{"name":"Xiaoming He","is_ca":false},{"name":"Zhinan Hong","is_ca":false},{"name":"Ziqi Li","is_ca":false},{"name":"Wei He","is_ca":false},{"name":"Qiushi Wei","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04058092539702055,"gpt":0.3192251172719696,"spread":0.278644191874949,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001989532,0.000134923,0.0002687062,0.00001476308,0.00009622866,0.00001034343,0.00004081044,0.0001166632,0.00005586264],"category_scores_gemma":[0.0003935526,0.0001093299,0.00007463284,0.0000725341,0.0003559894,0.00001107846,0.00004146785,0.0001030037,9.974628e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":9.474224e-7,"about_ca_system_score_gemma":0.0000709693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000175005,"about_ca_topic_score_gemma":0.00002199474,"domain_scores_codex":[0.9988595,0.00006779836,0.0003952685,0.0003879536,0.0001519736,0.0001375073],"domain_scores_gemma":[0.9994383,0.000147218,0.00007103097,0.0001140607,0.00009469662,0.0001347249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000973291,0.0006082192,0.08443065,0.0001444244,0.0003915722,0.00002760509,0.0007234127,0.000005566624,0.8930797,0.002522599,0.001419683,0.01567329],"study_design_scores_gemma":[0.009930338,0.000483263,0.8939776,0.0002164121,0.0004136069,0.00006414592,0.0006933577,0.00004869508,0.06024649,0.005911569,0.02760217,0.000412333],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798256,0.01326648,0.001851322,0.003303307,0.0001636831,0.0001325448,0.0001114677,0.000009338781,0.001336235],"genre_scores_gemma":[0.9931179,0.001815681,0.002196414,0.001160322,0.0007870588,0.000006110088,0.0005636478,0.0000113666,0.0003415196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8328332,"threshold_uncertainty_score":0.4458344,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3214733033","doi":"10.1002/ctm2.577","title":"Baicalein resensitizes tamoxifen‐resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia‐inducible factor‐1α","year":2021,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"CAE (Canada)","funders":"Natural Science Foundation of Guizhou Province; National Natural Science Foundation of China","keywords":"Baicalein; Cancer research; Tamoxifen; Anaerobic glycolysis; Pharmacology; Apoptosis; Cancer cell; Breast cancer; Chemistry; Medicine; Cancer; Biology; Internal medicine; Biochemistry","authors":[{"name":"Yan Chen","is_ca":true},{"name":"Jingyu Zhang","is_ca":true},{"name":"Minqin Zhang","is_ca":true},{"name":"Yuxuan Song","is_ca":false},{"name":"Yue Zhang","is_ca":false},{"name":"Shuangqin Fan","is_ca":false},{"name":"Shuang Ren","is_ca":false},{"name":"Lingyun Fu","is_ca":false},{"name":"Nenling Zhang","is_ca":false},{"name":"Hui Hui","is_ca":false},{"name":"Xiangchun Shen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01986764381361206,"gpt":0.2864714026627686,"spread":0.2666037588491565,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002114842,0.0001458433,0.0003551949,0.00004056881,0.0001059335,0.000009081289,0.00003059382,0.0002046933,0.0001091685],"category_scores_gemma":[0.00009199919,0.0001277629,0.00009224143,0.0001347868,0.0004224106,0.00001236974,0.0000219004,0.000154035,4.327219e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005141632,"about_ca_system_score_gemma":0.000095152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000166163,"about_ca_topic_score_gemma":0.00009906526,"domain_scores_codex":[0.9985085,0.0001287902,0.0005217154,0.0004694985,0.0002164247,0.000155059],"domain_scores_gemma":[0.9992625,0.0001171353,0.0001257397,0.0001500094,0.0001899047,0.0001547569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006880648,0.00006948448,0.0004922682,0.00005440978,0.00008320484,0.000001950572,0.00005564492,0.00001107191,0.980781,0.00003104571,0.002861456,0.01487043],"study_design_scores_gemma":[0.01457648,0.000733498,0.09069204,0.0007504206,0.0007717891,0.00009783754,0.0002066348,0.000266708,0.8308079,0.001213687,0.05924951,0.0006335406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829879,0.009643463,0.002063143,0.00346412,0.001377871,0.0001482281,0.0002091734,0.000007182333,0.00009893472],"genre_scores_gemma":[0.9919047,0.003969522,0.0004487851,0.0002470062,0.00287049,0.000006891456,0.0002640763,0.00001408266,0.0002744597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1499731,"threshold_uncertainty_score":0.5210022,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4391283790","doi":"10.1002/ctm2.1504","title":"Spinocerebellar ataxia 27B: A novel, frequent and potentially treatable ataxia","year":2024,"lang":"en","type":"review","venue":"Clinical and Translational Medicine","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":71,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council; UCLH Biomedical Research Centre; Else Kröner-Fresenius-Stiftung; Deutsche Forschungsgemeinschaft; Wellcome Trust","keywords":"Spinocerebellar ataxia; Medicine; Ataxia; Disease; Cerebellar ataxia; Trinucleotide repeat expansion; Bioinformatics; Natural history; Age of onset; Pediatrics; Allele; Genetics; Pathology; Internal medicine; Gene; Biology; Psychiatry","authors":[{"name":"David Pellerin","is_ca":true},{"name":"Matt C. Danzi","is_ca":false},{"name":"M. Renaud","is_ca":false},{"name":"Henry Houlden","is_ca":false},{"name":"Matthis Synofzik","is_ca":false},{"name":"Stephan Züchner","is_ca":false},{"name":"Bernard Brais","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1909312343690996,"gpt":0.4187261085204405,"spread":0.2277948741513409,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003347597,0.000516765,0.001469061,0.000155209,0.0001418279,0.00005606214,0.0002292068,0.0002343185,0.0002035705],"category_scores_gemma":[0.0006168683,0.0003336447,0.0002900724,0.0003131136,0.001049549,0.00007110629,0.00008237421,0.0005449958,0.00007296528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006234276,"about_ca_system_score_gemma":0.0002653943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001187342,"about_ca_topic_score_gemma":0.000007023446,"domain_scores_codex":[0.9964475,0.0002616464,0.001228478,0.001279319,0.0004961937,0.0002868499],"domain_scores_gemma":[0.9979234,0.001117019,0.0001931832,0.0003092308,0.00004831007,0.0004088091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004704084,0.0003030715,0.0002249261,0.01127596,0.0001966832,0.0001763465,0.00004929138,0.000001970856,0.0002476324,0.006533356,0.002918241,0.9780255],"study_design_scores_gemma":[0.001015522,0.0002992038,0.0003508359,0.005016332,0.002565121,0.0001701782,0.000002472539,0.00006263611,0.00002474104,0.001556785,0.9885659,0.0003702258],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003927485,0.9953246,0.0003981064,0.001251662,0.0007792226,0.0007199357,0.0006700839,0.00005665116,0.0004070257],"genre_scores_gemma":[0.0008523001,0.995908,0.0003146006,0.0006919221,0.0009521224,0.00004515038,0.000172963,0.00005833378,0.001004601],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9856477,"threshold_uncertainty_score":0.9999115,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2512289339","doi":"10.1186/s40169-016-0116-3","title":"Therapeutic use of stem cells for cardiovascular disease","year":2016,"lang":"en","type":"review","venue":"Clinical and Translational Medicine","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences North","funders":"","keywords":"Stem cell; Mesenchymal stem cell; Embryonic stem cell; Induced pluripotent stem cell; Medicine; Cardiac function curve; Clinical uses of mesenchymal stem cells; Cell type; Myocardial infarction; Adult stem cell; Disease; Stem cell transplantation for articular cartilage repair; Cell therapy; Cancer research; Bioinformatics; Cell; Cell biology; Pathology; Biology; Heart failure; Internal medicine; Genetics","authors":[{"name":"Whitney Faiella","is_ca":true},{"name":"Rony Atoui","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2825908453026095,"gpt":0.4173270649184024,"spread":0.134736219615793,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006467373,0.0003282429,0.002721736,0.0001343121,0.00003556499,0.000002572018,0.00006318379,0.0002316316,0.00004602727],"category_scores_gemma":[0.0001039811,0.0001620627,0.001254725,0.0001205554,0.0006202038,0.00002862585,0.00000847536,0.0002510182,0.000004169644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006271756,"about_ca_system_score_gemma":0.0001900341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001771237,"about_ca_topic_score_gemma":9.922225e-8,"domain_scores_codex":[0.9977523,0.0001259002,0.001128481,0.0004426009,0.0003765774,0.0001741506],"domain_scores_gemma":[0.9967826,0.002162535,0.0001570165,0.0003668061,0.0001476607,0.0003834034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008642305,0.00006554194,0.00006431618,0.0138484,0.002469611,0.00001515606,0.00001356917,0.000003344391,0.000001796495,0.001665451,0.0002659033,0.9815005],"study_design_scores_gemma":[0.002382654,0.0004160794,0.0001706251,0.02556169,0.009173566,0.00001975948,0.000001773516,0.00004712871,8.442034e-7,0.0001075709,0.9619613,0.0001570255],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000009964368,0.974645,0.02225369,0.0009096893,0.0007641067,0.001201871,0.0001811183,0.00002680167,0.000007740116],"genre_scores_gemma":[0.0001963638,0.9942816,0.0005613745,0.00004390977,0.001996158,0.0000717947,0.000124651,0.00005080991,0.002673291],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9813434,"threshold_uncertainty_score":0.6608726,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4296804188","doi":"10.1002/ctm2.1056","title":"Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids","year":2022,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pancreas Centre (Canada)","funders":"Japan Society for the Promotion of Science; Japan Agency for Medical Research and Development","keywords":"Sphingolipid; Sphingosine; Colorectal cancer; Sphingosine-1-phosphate; Cancer; Cancer research; Cancer cell; Chemistry; Biology; Receptor; Biochemistry; Medicine; Internal medicine","authors":[{"name":"Baasanjav Uranbileg","is_ca":false},{"name":"Makoto Kurano","is_ca":false},{"name":"Kuniyuki Kano","is_ca":false},{"name":"Eri Sakai","is_ca":false},{"name":"Junichi Arita","is_ca":true},{"name":"Kiyoshi Hasegawa","is_ca":true},{"name":"Takeshi Nishikawa","is_ca":false},{"name":"Soichiro Ishihara","is_ca":false},{"name":"Hiroharu Yamashita","is_ca":false},{"name":"Yasuyuki Seto","is_ca":false},{"name":"Hitoshi Ikeda","is_ca":false},{"name":"Junken Aoki","is_ca":false},{"name":"Yutaka Yatomi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0414749211608464,"gpt":0.3750701590109869,"spread":0.3335952378501406,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008503838,0.0002160198,0.0003710447,0.00004128922,0.0003896542,0.00001219934,0.0001882136,0.00008869088,0.0004648266],"category_scores_gemma":[0.0002854137,0.0001769577,0.0001054011,0.0002147832,0.0002771226,0.00001166746,0.0001405055,0.0002736764,0.000004174605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005547556,"about_ca_system_score_gemma":0.00008730559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001440776,"about_ca_topic_score_gemma":0.00001052045,"domain_scores_codex":[0.9979074,0.0001255624,0.0006830484,0.0005898015,0.0003930264,0.000301184],"domain_scores_gemma":[0.9992115,0.0001272135,0.0001165861,0.000208292,0.00009650028,0.0002399174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007439202,0.0009006949,0.4367293,0.0004015762,0.0006232183,0.00004696508,0.005999851,0.004167119,0.3220066,0.005590629,0.01297373,0.2031212],"study_design_scores_gemma":[0.01027691,0.002371079,0.07879973,0.0002331191,0.0002268549,0.00004624072,0.0006898477,0.001189067,0.01724166,0.002612556,0.8854446,0.0008683382],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744211,0.01256114,0.001946279,0.009042991,0.001352164,0.0003529518,0.00008657132,0.00003118776,0.0002056489],"genre_scores_gemma":[0.9906586,0.0008632151,0.001230329,0.00481215,0.001807524,0.0001163311,0.0001918205,0.00002741928,0.0002925802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8724709,"threshold_uncertainty_score":0.7216124,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4213074975","doi":"10.1002/ctm2.722","title":"EEF2K silencing inhibits tumour progression through repressing SPP1 and synergises with BET inhibitors in melanoma","year":2022,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Melanoma; Cancer research; Gene silencing; Small interfering RNA; STAT3; Chromatin immunoprecipitation; Medicine; Biology; Transfection; Cell culture; Phosphorylation; Cell biology; Gene expression; Promoter","authors":[{"name":"Guangtong Deng","is_ca":true},{"name":"Furong Zeng","is_ca":true},{"name":"Yi He","is_ca":true},{"name":"Yu Meng","is_ca":true},{"name":"Huiyan Sun","is_ca":true},{"name":"Juan Su","is_ca":true},{"name":"Shuang Zhao","is_ca":true},{"name":"Yan Cheng","is_ca":false},{"name":"Xiang Chen","is_ca":true},{"name":"Mingzhu Yin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02666650762524162,"gpt":0.327150321323421,"spread":0.3004838136981793,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004977082,0.0001231143,0.0001983105,0.00004479309,0.0001649958,0.000008815002,0.00005444067,0.00007123265,0.00003424487],"category_scores_gemma":[0.0001012877,0.00009016678,0.00002723474,0.0001216779,0.0003191638,0.00001408349,0.00005982341,0.0002174526,2.577994e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003362011,"about_ca_system_score_gemma":0.00005699363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002952594,"about_ca_topic_score_gemma":0.00002405978,"domain_scores_codex":[0.998677,0.0001358387,0.0004231598,0.0003931449,0.0002386723,0.0001321976],"domain_scores_gemma":[0.9996012,0.0000837623,0.0001009354,0.0001016194,0.00003260459,0.00007985776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001907686,0.0004990453,0.7559658,0.0001589823,0.0001019815,0.00007468306,0.00138823,0.0002414963,0.1398655,0.001886567,0.001952286,0.09595768],"study_design_scores_gemma":[0.03046501,0.01147073,0.6957474,0.002514245,0.0002333523,0.000586625,0.003370852,0.001843087,0.1570897,0.008351196,0.08651503,0.001812738],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911199,0.004131968,0.0002600994,0.003477789,0.0001261641,0.0002304313,0.00000772894,0.00001092725,0.000635002],"genre_scores_gemma":[0.9979243,0.0002202163,0.00083045,0.0004485735,0.0003531773,0.00003448466,0.0001145958,0.00001197258,0.00006219706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09414494,"threshold_uncertainty_score":0.3676895,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2138964074","doi":"10.1186/s40169-015-0058-1","title":"Association between the <i>TCF7L2</i> rs12255372 (G/T) gene polymorphism and type 2 diabetes mellitus in a Cameroonian population: a pilot study","year":2015,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; Centre for Drug Research and Development","funders":"VLIRUOS; Vlaamse Interuniversitaire Raad; Newcastle University","keywords":"TCF7L2; Genotype; Genotyping; Allele; Internal medicine; Type 2 Diabetes Mellitus; Medicine; Odds ratio; Gastroenterology; Type 2 diabetes; Population; Polymorphism (computer science); Diabetes mellitus; Allele frequency; Endocrinology; Genetics; Biology; Single-nucleotide polymorphism; Gene","authors":[{"name":"Dieudonne Nanfa","is_ca":false},{"name":"Eugène Sobngwi","is_ca":false},{"name":"Barbara Atogho‐Tiedeu","is_ca":false},{"name":"Jean Jacques Noubiap","is_ca":false},{"name":"Olivier Sontsa Donfack","is_ca":false},{"name":"Edith Pascale Mato Mofo","is_ca":false},{"name":"Magellan Guewo‐Fokeng","is_ca":false},{"name":"A. Nguimmo Metsadjio","is_ca":false},{"name":"Elvis Ndonwi Ngwa","is_ca":false},{"name":"Priscille Pokam Fosso","is_ca":false},{"name":"E. Djahmeni","is_ca":false},{"name":"Rosine Djokam-Dadjeu","is_ca":false},{"name":"Marie‐Solange Evehe","is_ca":false},{"name":"Folefac Aminkeng","is_ca":true},{"name":"Wilfred Fon Mbacham","is_ca":false},{"name":"Jean Claude Mbanya","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07160303761153233,"gpt":0.3449126566437957,"spread":0.2733096190322634,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001917047,0.0001099561,0.0002835207,0.00003124138,0.00007197228,0.00000596365,0.0000635116,0.0001102404,0.000007183718],"category_scores_gemma":[0.0007915817,0.00007555657,0.00002239532,0.0001154371,0.0001276652,0.000005107724,0.00002624974,0.0001467892,0.000002117615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007529759,"about_ca_system_score_gemma":0.00004126503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001805052,"about_ca_topic_score_gemma":0.0003190035,"domain_scores_codex":[0.9985341,0.0003545412,0.0005131677,0.000271514,0.0001607111,0.0001659587],"domain_scores_gemma":[0.9991514,0.0003870834,0.0001299411,0.0001224183,0.00008817134,0.0001209697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004469553,0.000107475,0.995172,0.000002719557,0.00009180563,4.742602e-7,0.0001043968,0.00001181343,0.0000730715,0.00003162213,0.0003703182,0.003989583],"study_design_scores_gemma":[0.002044925,0.002438046,0.9916267,0.000009157808,0.00009533142,0.000001172018,0.0000793114,0.00007670632,0.00000394579,0.001623109,0.001916787,0.00008484661],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841954,0.004574346,0.00009855565,0.01058946,0.0001752949,0.000246859,0.00001107339,0.000005158226,0.0001039182],"genre_scores_gemma":[0.9977044,0.0004444504,0.0002327358,0.0006093182,0.0007294113,0.00001316626,0.0001499072,0.000008179473,0.0001083935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01350911,"threshold_uncertainty_score":0.3081107,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2970704131","doi":"10.1186/s40169-019-0241-x","title":"New therapeutic targets for cancer: the interplay between immune and metabolic checkpoints and gut microbiota","year":2019,"lang":"en","type":"review","venue":"Clinical and Translational Medicine","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Immune system; Immunosurveillance; Tumor microenvironment; Immune checkpoint; Cancer research; Biology; Cancer; Immunotherapy; Pembrolizumab; Immunology; Medicine","authors":[{"name":"Babita Agrawal","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1249707252379751,"gpt":0.459149010774388,"spread":0.3341782855364129,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009172339,0.0003767502,0.002212531,0.00009111463,0.0001021426,0.00001707253,0.000119801,0.000338874,0.0001844963],"category_scores_gemma":[0.00006093249,0.0001917822,0.0003650009,0.0001402703,0.0006802373,0.00003906734,0.00002602873,0.0004823648,0.000002509707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007772184,"about_ca_system_score_gemma":0.0003270587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009668055,"about_ca_topic_score_gemma":0.000019542,"domain_scores_codex":[0.9978327,0.0001133276,0.001163537,0.000497272,0.0001729358,0.0002202576],"domain_scores_gemma":[0.9974335,0.001809267,0.0002846791,0.0002352519,0.00005770746,0.0001796272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003915586,0.00001912318,0.001104798,0.0034347,0.001613928,8.563374e-7,0.000125455,4.911626e-9,0.00001653299,0.0001331243,0.0005301133,0.9926298],"study_design_scores_gemma":[0.00491576,0.0003887914,0.03138071,0.007329445,0.005494462,0.00006067922,0.00001267999,0.000004994439,0.00000121243,0.0003654901,0.9498454,0.0002003518],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001091949,0.9855868,0.0002798731,0.01154148,0.0005318034,0.001711743,0.0001641514,0.00001422777,0.00006070763],"genre_scores_gemma":[0.0006205296,0.9953332,0.0002417207,0.0009193959,0.001576663,0.00005490786,0.0002693562,0.00004083785,0.0009434221],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9924294,"threshold_uncertainty_score":0.7820651,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4385264134","doi":"10.1002/ctm2.1340","title":"Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil","year":2023,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Natural Science Foundation of China","keywords":"Tumor microenvironment; Stromal cell; Cancer research; Biology; Transcriptome; CD163; Gene signature; Immune system; Immunology; Medicine; Phenotype; Gene expression; Gene","authors":[{"name":"Haoxin Peng","is_ca":false},{"name":"Xiangrong Wu","is_ca":false},{"name":"Shaopeng Liu","is_ca":true},{"name":"Miao He","is_ca":false},{"name":"Chenshuo Tang","is_ca":false},{"name":"Yaokai Wen","is_ca":false},{"name":"Chao Xie","is_ca":false},{"name":"Ran Zhong","is_ca":false},{"name":"Caichen Li","is_ca":false},{"name":"Shan Xiong","is_ca":false},{"name":"Jun Liu","is_ca":false},{"name":"Hongbo Zheng","is_ca":false},{"name":"Jianxing He","is_ca":false},{"name":"Xu Lu","is_ca":true},{"name":"Wenhua Liang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02382050627847456,"gpt":0.3159438169901303,"spread":0.2921233107116558,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002560837,0.0001132122,0.0002809917,0.00006760671,0.00006136444,0.000001100551,0.00005416828,0.0001346818,0.00007155953],"category_scores_gemma":[0.00001344705,0.00008098004,0.00002781793,0.00009969452,0.00107101,0.00003084658,0.00002905144,0.00023735,0.000002075503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001939543,"about_ca_system_score_gemma":0.00004676328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001841611,"about_ca_topic_score_gemma":0.0003524305,"domain_scores_codex":[0.9989998,0.000103606,0.0004225168,0.0002556902,0.00006412846,0.0001542055],"domain_scores_gemma":[0.9995383,0.0002460713,0.00009122962,0.00007818629,0.00002106843,0.00002513593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005722468,0.00009119642,0.9786974,0.0001100049,0.00009518624,0.00001456203,0.000125263,0.000111219,0.01195534,0.000249433,0.00007691262,0.007901277],"study_design_scores_gemma":[0.003858043,0.0003101732,0.9918351,0.0003784968,0.00007905061,0.00001434226,0.00007582544,0.00145124,0.001309493,0.0003863085,0.0002009111,0.0001010021],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795321,0.01583126,0.0002302275,0.003804178,0.0003006896,0.0002319712,0.00003008824,0.00001312494,0.00002637666],"genre_scores_gemma":[0.9975257,0.001996981,0.00006811665,0.0000652531,0.00005616286,0.00001860761,0.0002130606,0.000009773382,0.00004633285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01799363,"threshold_uncertainty_score":0.3946182,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3172938495","doi":"10.1002/ctm2.417","title":"Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice","year":2021,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Adipose triglyceride lipase; Adipose tissue; White adipose tissue; Hypermetabolism; Medicine; Internal medicine; Endocrinology; Burn injury; Catabolism; Adipocyte; Sepsis; Cachexia; Lipolysis; Cancer; Metabolism; Surgery","authors":[{"name":"Supreet Kaur","is_ca":true},{"name":"Christopher Auger","is_ca":true},{"name":"Dalia Barayan","is_ca":true},{"name":"Priyal Shah","is_ca":true},{"name":"Anna Matveev","is_ca":true},{"name":"Carly M. Knuth","is_ca":true},{"name":"Thurl E. Harris","is_ca":false},{"name":"Marc G. Jeschke","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08755096571557601,"gpt":0.3857848672840188,"spread":0.2982339015684428,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006708798,0.0001855325,0.0006665874,0.0001463547,0.0000679971,0.000009026932,0.00005608018,0.0001764697,0.000671836],"category_scores_gemma":[0.0002734972,0.0001477966,0.00009686815,0.0004145785,0.0002070667,0.0001247306,0.00001525527,0.000383057,0.00003563509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004891789,"about_ca_system_score_gemma":0.000117666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002413897,"about_ca_topic_score_gemma":0.00002273724,"domain_scores_codex":[0.99785,0.0001446898,0.0009125402,0.0004613457,0.0003990893,0.0002323226],"domain_scores_gemma":[0.99894,0.000341548,0.00009740575,0.0001679675,0.0001879453,0.0002651488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001495905,0.001185637,0.1772056,0.0001538874,0.0005801399,0.0003642688,0.001845935,0.000003950002,0.07458848,0.01644846,0.002039131,0.7240885],"study_design_scores_gemma":[0.006905365,0.0002323942,0.8729993,0.0002989867,0.000381805,0.00006446521,0.0001043859,0.0000895105,0.002834468,0.003430368,0.1124818,0.0001770769],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9451908,0.03163085,0.0001888252,0.01883121,0.0006738893,0.0003322013,0.00001008281,0.00003226459,0.003109892],"genre_scores_gemma":[0.9891666,0.005452956,0.001202768,0.001595078,0.001530344,0.0000147238,0.0001738485,0.00001976167,0.0008439066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7239115,"threshold_uncertainty_score":0.7356133,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4391170098","doi":"10.1002/ctm2.1544","title":"Seize the engine: Emerging cell cycle targets in breast cancer","year":2024,"lang":"en","type":"review","venue":"Clinical and Translational Medicine","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Breast Cancer Research Foundation; Princess Margaret Cancer Foundation; American Society of Clinical Oncology; National Cancer Institute; Conquer Cancer Foundation","keywords":"Breast cancer; Medicine; Cancer; Internal medicine","authors":[{"name":"Jesús Fuentes‐Antrás","is_ca":true},{"name":"Philippe L. Bédard","is_ca":true},{"name":"David W. Cescon","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06372966994859343,"gpt":0.442115601207799,"spread":0.3783859312592056,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006003097,0.0003803635,0.001611937,0.0001495657,0.00005230065,0.000006859993,0.000123394,0.0002420919,0.0003413246],"category_scores_gemma":[0.00003898767,0.0001916921,0.0003080595,0.0004051007,0.000505165,0.00004644586,0.0000254664,0.001196974,0.00001890033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000268133,"about_ca_system_score_gemma":0.0003814777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002487202,"about_ca_topic_score_gemma":0.00001420501,"domain_scores_codex":[0.9976568,0.00009056034,0.001127738,0.000515117,0.0003484614,0.0002612728],"domain_scores_gemma":[0.998694,0.0007021946,0.0001434998,0.0002236492,0.00005759779,0.0001790646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007069559,0.00006157792,0.0002814697,0.007910239,0.0001971363,0.0000447316,0.0001612975,0.00001962754,3.376485e-7,0.0002182811,0.0003370791,0.9906975],"study_design_scores_gemma":[0.001884032,0.00005574392,0.001711392,0.024124,0.002351063,0.0002050471,0.00002573268,0.0007090523,8.097405e-8,0.001901244,0.9668005,0.0002321617],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001403385,0.9757344,0.0001850632,0.02220283,0.0006098227,0.0006084496,0.0001418325,0.00004403504,0.0004595422],"genre_scores_gemma":[0.0009724808,0.9949719,0.0002248896,0.0008589295,0.002131813,0.0001273614,0.00009709135,0.00006310634,0.0005524097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9904653,"threshold_uncertainty_score":0.7816976,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2117437539","doi":"10.1186/s40169-014-0028-z","title":"Transcriptional factor snail controls tumor neovascularization, growth and metastasis in mouse model of human ovarian carcinoma","year":2014,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Snail; Ovarian carcinoma; Metastasis; Medicine; Ovarian cancer; Oncology; Neovascularization; Cancer research; Internal medicine; Angiogenesis; Cancer; Biology; Ecology","authors":[{"name":"Samar Abdulkhalek","is_ca":true},{"name":"Olivia Geen","is_ca":true},{"name":"Lacey Brodhagen","is_ca":true},{"name":"Fiona Haxho","is_ca":true},{"name":"Farah Alghamdi","is_ca":true},{"name":"Stephanie Allison‐Logan","is_ca":true},{"name":"Duncan Simmons","is_ca":true},{"name":"Leah O'Shea","is_ca":true},{"name":"Ronald J. Neufeld","is_ca":true},{"name":"Myron R. Szewczuk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0408144616876839,"gpt":0.29525566596602,"spread":0.2544412042783362,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003950821,0.0001426744,0.0003247366,0.00008255334,0.00005111322,0.000005838768,0.0000647547,0.0001208611,0.00002761672],"category_scores_gemma":[0.0001200916,0.0001222895,0.00008353475,0.00006561308,0.0004190831,0.00001448952,0.000006516078,0.0001066921,2.487712e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001632669,"about_ca_system_score_gemma":0.00003190741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003334122,"about_ca_topic_score_gemma":0.00004658965,"domain_scores_codex":[0.9985761,0.0001360258,0.0006345364,0.0003250862,0.0002110056,0.0001172174],"domain_scores_gemma":[0.9995087,0.00006987488,0.00008685819,0.0001201384,0.0001025926,0.0001118608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002413616,0.0001278838,0.2584032,0.00008364274,0.00008289165,3.437443e-7,0.0001687508,0.0002455438,0.7131397,0.02611977,0.00001015057,0.001376782],"study_design_scores_gemma":[0.009009587,0.0005896103,0.9607544,0.00003643789,0.0001011266,0.000004783979,0.00002413009,0.01258332,0.009465394,0.006932592,0.0002742445,0.0002243658],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9574807,0.0004017544,0.04044846,0.001223606,0.00004719342,0.0001976884,0.00008730073,0.000006859237,0.0001064092],"genre_scores_gemma":[0.9982126,0.0000643594,0.0009450804,0.000269995,0.000132423,0.00000944467,0.0003103987,0.00001317478,0.00004253316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7036743,"threshold_uncertainty_score":0.498682,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3033105670","doi":"10.1002/ctm2.25","title":"Identification of potential candidate genes and pathways in atrioventricular nodal reentry tachycardia by whole‐exome sequencing","year":2020,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Cardiac Arrhythmias and Treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre for Global Health Research","funders":"National Natural Science Foundation of China","keywords":"Candidate gene; Exome sequencing; Genetics; Gene; Medicine; Exome; Bioinformatics; Biology; Mutation","authors":[{"name":"Rong Luo","is_ca":false},{"name":"Chenqing Zheng","is_ca":false},{"name":"Hao Yang","is_ca":false},{"name":"Xuepin Chen","is_ca":false},{"name":"Panpan Jiang","is_ca":false},{"name":"Xiushan Wu","is_ca":false},{"name":"Zhenglin Yang","is_ca":false},{"name":"Xia Shen","is_ca":true},{"name":"Xiaoping Li","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03152888529515319,"gpt":0.3023817559517857,"spread":0.2708528706566325,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002779813,0.0001197462,0.0004923814,0.00005163448,0.00004102098,0.000003801042,0.00002470964,0.00009732375,0.00001701885],"category_scores_gemma":[0.0001139296,0.00009188726,0.0001032894,0.0001526107,0.0002602802,0.00006143007,0.00001382283,0.0001529556,0.000002297538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000795784,"about_ca_system_score_gemma":0.0000655347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000575054,"about_ca_topic_score_gemma":0.000002774372,"domain_scores_codex":[0.9985009,0.00006028139,0.0007267852,0.0003033435,0.0002900047,0.0001186648],"domain_scores_gemma":[0.9993764,0.0001358089,0.0001152617,0.00008811468,0.0000613361,0.0002230386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009833165,0.0001634186,0.9348111,0.0002975585,0.0004271753,0.001142422,0.0008363139,0.00006146517,0.02181635,0.0002675505,0.0005220795,0.03867124],"study_design_scores_gemma":[0.01241082,0.0005697548,0.9786214,0.0001930461,0.0005753203,0.0003585613,0.0001698482,0.004003058,0.000712831,0.0004348837,0.001777419,0.0001730472],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799426,0.0092577,0.0008188012,0.009368838,0.0001141534,0.0002823548,0.0001420108,0.00001280185,0.00006076917],"genre_scores_gemma":[0.9962799,0.002599919,0.0001053163,0.000329334,0.0003745781,0.000005895893,0.000278372,0.000009678041,0.00001699386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0438103,"threshold_uncertainty_score":0.3747054,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2508757450","doi":"10.1186/s40169-016-0109-2","title":"A quantitative metabolomics profiling approach for the noninvasive assessment of liver histology in patients with chronic hepatitis C","year":2016,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; Health Sciences Centre; McMaster University Medical Centre; McGill University Health Centre; University of Calgary","funders":"Alberta Innovates; Alberta Heritage Foundation for Medical Research; Alberta Innovates - Health Solutions; Canadian Institutes of Health Research; China Scholarship Council; American Gastroenterological Association; Canadian Liver Foundation; Alberta Cancer Foundation; Fondation pour la Recherche Médicale","keywords":"Chronic hepatitis; Medicine; Profiling (computer programming); Histology; Metabolomics; Pathology; Internal medicine; Bioinformatics; Computer science; Virology; Biology","authors":[{"name":"M. Omair Sarfaraz","is_ca":true},{"name":"Robert P. Myers","is_ca":true},{"name":"Carla S. Coffin","is_ca":true},{"name":"Zu‐Hua Gao","is_ca":true},{"name":"Abdel Aziz Shaheen","is_ca":true},{"name":"Pam Crotty","is_ca":true},{"name":"Ping Zhang","is_ca":true},{"name":"Hans J. Vogel","is_ca":true},{"name":"Aalim M. Weljie","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05861534465803177,"gpt":0.359647062491502,"spread":0.3010317178334703,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002603377,0.00009899781,0.0003908576,0.00004463587,0.00003399512,0.000001043024,0.00003554692,0.00005000269,0.00002979305],"category_scores_gemma":[0.0001082905,0.00004055883,0.00006469588,0.00006602167,0.0005265506,0.00003769213,0.000006243213,0.00007067878,3.108705e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002030248,"about_ca_system_score_gemma":0.0001705859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005008501,"about_ca_topic_score_gemma":0.00005553874,"domain_scores_codex":[0.999043,0.00005406737,0.0003946311,0.0002221168,0.0001802624,0.0001059382],"domain_scores_gemma":[0.9975438,0.002008433,0.000109424,0.00009738232,0.0001712021,0.00006980725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000804037,0.0006739225,0.9735962,0.00008230856,0.000320576,0.000003182988,0.00006750018,0.00000659687,0.000007980708,0.01288042,0.00001688748,0.01154045],"study_design_scores_gemma":[0.01349615,0.002945743,0.9807344,0.000201194,0.0005693973,0.000001432421,0.00001377403,0.001589509,0.00001500278,0.0002934038,0.00008859018,0.00005140759],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676178,0.003724607,0.02167943,0.00487729,0.0000775986,0.001741376,0.0001239391,0.000006681428,0.0001513115],"genre_scores_gemma":[0.9883716,0.001073861,0.01005756,0.0001513315,0.0000713942,0.000155778,0.00009790198,0.000007765583,0.00001282688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02075382,"threshold_uncertainty_score":0.1940098,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4206935838","doi":"10.1002/ctm2.581","title":"Subversion of infiltrating prostate macrophages to a mixed immunosuppressive tumor‐associated macrophage phenotype","year":2022,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Cancer Research Society","keywords":"CD163; Tumor microenvironment; Prostate cancer; Chemokine; Proinflammatory cytokine; Cancer research; CCL22; CCL25; Macrophage; Prostate; Biology; Cytokine; M2 Macrophage; Immunology; CXCL10; Medicine; Cancer; Inflammation; Immune system; In vitro","authors":[{"name":"Clovis Boibessot","is_ca":true},{"name":"Oscar Eduardo Molina","is_ca":true},{"name":"Gabriel Lachance","is_ca":true},{"name":"Christophe Tav","is_ca":true},{"name":"Audrey Champagne","is_ca":true},{"name":"Bertrand Neveu","is_ca":true},{"name":"Jean‐François Pelletier","is_ca":true},{"name":"Frédéric Pouliot","is_ca":true},{"name":"Vincent Fradet","is_ca":true},{"name":"Steve Bilodeau","is_ca":true},{"name":"Yves Fradet","is_ca":true},{"name":"Alain Bergeron","is_ca":true},{"name":"Paul Toren","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02100315946181896,"gpt":0.3016135617219565,"spread":0.2806104022601376,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007930969,0.0001378929,0.0004118121,0.00007966698,0.0002736242,0.000002539961,0.0001653959,0.00007845229,0.002136508],"category_scores_gemma":[0.000346411,0.0001166393,0.00007385711,0.0002248422,0.0005389715,0.00003908445,0.00009618328,0.0004831819,0.00001851299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001193852,"about_ca_system_score_gemma":0.0000717314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007925254,"about_ca_topic_score_gemma":0.000005941129,"domain_scores_codex":[0.9982806,0.0003948386,0.000715913,0.0002837266,0.0001119599,0.0002128903],"domain_scores_gemma":[0.9986051,0.000889498,0.0002196658,0.0001445195,0.0001056614,0.00003553624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005841126,0.0009996796,0.1312481,0.0001825528,0.001002108,0.00008462508,0.007159895,0.0005095972,0.788573,0.002008135,0.01137779,0.05101349],"study_design_scores_gemma":[0.02481541,0.005779135,0.8790095,0.0004602644,0.0004478292,0.0001069933,0.002336221,0.0001357794,0.04043793,0.004459525,0.04128977,0.0007216395],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860296,0.008146292,0.00005938582,0.003137344,0.001500083,0.0003635726,0.0001688663,0.00002909568,0.0005657992],"genre_scores_gemma":[0.9980564,0.0000739397,0.0001307469,0.0005747078,0.00004863015,0.00003092935,0.0002454894,0.00001391685,0.0008252528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.748135,"threshold_uncertainty_score":0.9987757,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3090576692","doi":"10.1002/ctm2.194","title":"Improving transgene expression and CRISPR‐Cas9 efficiency with molecular engineering‐based molecules","year":2020,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"CAE (Canada)","funders":"National Key Research and Development Program of China; Natural Science Foundation of Guangdong Province; Government of Jiangxi Province; National Natural Science Foundation of China","keywords":"CRISPR; Cas9; Transgene; Genome editing; Biology; Gene; Computational biology; Genetic enhancement; Plasmid; Cell biology; Genetics","authors":[{"name":"Hengji Zhan","is_ca":true},{"name":"Mengting Ding","is_ca":true},{"name":"Qun Zhou","is_ca":true},{"name":"Aolin Li","is_ca":true},{"name":"Zhiming Cai","is_ca":false},{"name":"Weiren Huang","is_ca":false},{"name":"Yuchen Liu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01574441857816584,"gpt":0.3119143305036433,"spread":0.2961699119254775,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119608,0.0001428245,0.0001775754,0.00002145085,0.00003493932,0.000006585394,0.00005627599,0.00009106796,0.000009769074],"category_scores_gemma":[0.00007400888,0.0001069584,0.00003764452,0.00006338448,0.0001423557,0.000002898466,0.00001172235,0.0001131658,3.533291e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":5.004624e-7,"about_ca_system_score_gemma":0.00002468606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002322641,"about_ca_topic_score_gemma":9.420589e-7,"domain_scores_codex":[0.99913,0.00001957366,0.000249825,0.0003351979,0.0001354752,0.0001299061],"domain_scores_gemma":[0.9995906,0.0000489893,0.00002742623,0.00008894555,0.00003476671,0.0002093174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002424383,0.00003837378,0.004119588,0.0001689172,0.00003403339,0.00001578217,0.00008724323,0.005850131,0.9816875,0.0001284165,0.00002818192,0.007599366],"study_design_scores_gemma":[0.01771686,0.006537686,0.06141991,0.0005218958,0.0003942729,0.00007302916,0.0001275266,0.2395993,0.6600791,0.0001224098,0.01210767,0.001300377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4186034,0.002928104,0.5761815,0.002080968,0.00003368867,0.0001092173,0.000006418336,0.0000150737,0.00004164783],"genre_scores_gemma":[0.9910181,0.0001039066,0.007918269,0.0006729598,0.0002114751,0.000006785201,0.00004727108,0.00001733283,0.000003879792],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5724148,"threshold_uncertainty_score":0.4361636,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3123323752","doi":"10.1002/ctm2.236","title":"Association of circulating tumor DNA from the cerebrospinal fluid with high‐risk CNS involvement in patients with diffuse large B‐cell lymphoma","year":2021,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Ontario Power Generation","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Diffuse large B-cell lymphoma; Medicine; Cerebrospinal fluid; Liquid biopsy; Lymphoma; Pathology; Oncology; International Prognostic Index; Internal medicine; Oncogene; Cancer research; Cancer; Cell cycle","authors":[{"name":"Xiaoxiao Wang","is_ca":false},{"name":"Yan Gao","is_ca":false},{"name":"Changguo Shan","is_ca":false},{"name":"Mingyao Lai","is_ca":false},{"name":"Haixia He","is_ca":false},{"name":"Bing Bai","is_ca":false},{"name":"Liqin Ping","is_ca":false},{"name":"Qixiang Rong","is_ca":false},{"name":"Ruyu Ai","is_ca":false},{"name":"Lei Wen","is_ca":false},{"name":"Zhaoming Zhou","is_ca":false},{"name":"Ruoying Yu","is_ca":true},{"name":"Qiuxiang Ou","is_ca":true},{"name":"Xue Wu","is_ca":true},{"name":"Xiaoxia Wang","is_ca":false},{"name":"Yang Shao","is_ca":false},{"name":"Linbo Cai","is_ca":false},{"name":"Huiqiang Huang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01880582760232571,"gpt":0.2545990550353621,"spread":0.2357932274330364,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000459863,0.0003558768,0.001061747,0.00006962165,0.00009681817,0.00001338069,0.00008989441,0.0003313751,0.0001435343],"category_scores_gemma":[0.0001717057,0.0001848171,0.0001344665,0.0002111643,0.0002178898,0.00004932836,0.00002327002,0.0005626655,0.00000270218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009377579,"about_ca_system_score_gemma":0.0002810918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007242338,"about_ca_topic_score_gemma":0.0003203284,"domain_scores_codex":[0.9966428,0.0002537019,0.001063964,0.0005883969,0.00115016,0.0003010296],"domain_scores_gemma":[0.9964876,0.00214178,0.0006452477,0.0003215038,0.0002892913,0.0001145764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005077489,0.002994608,0.9829727,0.0001464805,0.0007442547,0.0001695937,0.000252738,0.000001343531,0.000001384681,0.00002112708,0.01042377,0.001764222],"study_design_scores_gemma":[0.06306546,0.001524115,0.924136,0.001730519,0.00171779,0.000002915503,0.00004622119,0.00004152093,0.0000103351,0.0001326464,0.007409038,0.0001834116],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8500397,0.0007452731,0.00002568802,0.1477622,0.0001669029,0.0006829099,0.0004805792,0.00001210518,0.00008464855],"genre_scores_gemma":[0.9274755,0.0002264884,0.0003172071,0.0657367,0.001431063,0.00005624918,0.004637389,0.00003793384,0.00008153197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08202554,"threshold_uncertainty_score":0.7536623,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4310642745","doi":"10.1002/ctm2.1117","title":"LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus","year":2022,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"National Natural Science Foundation of China","keywords":"Biology; Immunology; Epigenetics; Cancer research; Cell biology; Genetics; Gene","authors":[{"name":"Limin Liu","is_ca":true},{"name":"Longyuan Hu","is_ca":true},{"name":"Haojun Long","is_ca":true},{"name":"Meiling Zheng","is_ca":true},{"name":"Zhi Hu","is_ca":true},{"name":"Ye He","is_ca":true},{"name":"Xiaofei Gao","is_ca":true},{"name":"Pei Du","is_ca":true},{"name":"Hongjun Zhao","is_ca":false},{"name":"Di Yu","is_ca":false},{"name":"Qianjin Lu","is_ca":false},{"name":"Ming Zhao","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03686639790584809,"gpt":0.3309388066557554,"spread":0.2940724087499073,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001196988,0.0002087818,0.0008116837,0.0002867688,0.00008442772,0.000007446751,0.0001041645,0.00009427272,0.0001798542],"category_scores_gemma":[0.0002088731,0.0001377652,0.00005776352,0.0003406606,0.0002240477,0.00007218305,0.00007324725,0.0004902274,0.000002905056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003355489,"about_ca_system_score_gemma":0.0001241244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004973632,"about_ca_topic_score_gemma":0.00001767159,"domain_scores_codex":[0.9969169,0.0002729108,0.001127635,0.000490549,0.0009393823,0.0002525673],"domain_scores_gemma":[0.998558,0.0005301257,0.0002242374,0.0002506991,0.0001408288,0.000296066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009255804,0.001114778,0.8147748,0.004761237,0.0002441776,0.0001853099,0.009571029,0.00004854001,0.1494409,0.000874573,0.0004104746,0.009318396],"study_design_scores_gemma":[0.1520979,0.02783169,0.5879867,0.1148844,0.001050175,0.04849849,0.0119681,0.02167739,0.02121308,0.006493914,0.004147581,0.002150554],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925252,0.00106695,0.0003726425,0.003471209,0.0001923947,0.002073108,0.0000300648,0.0000220468,0.0002464248],"genre_scores_gemma":[0.9984497,0.00007116648,0.0004940617,0.0001028418,0.0001444964,0.000177428,0.00004825996,0.00002808023,0.0004839172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2267881,"threshold_uncertainty_score":0.5617902,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2098306188","doi":"10.1186/2001-1326-1-6","title":"Integrative medicine and human health ‐ the role of pre‐, pro‐ and synbiotics","year":2012,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Barrie Urology Group","funders":"","keywords":"Synbiotics; Immune system; Medicine; Curcumin; Inflammation; Disease; Immunity; Biotechnology; Biology; Immunology; Probiotic; Bacteria; Pharmacology; Internal medicine","authors":[{"name":"Stig Bengmark","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04407470916204932,"gpt":0.3911953708467423,"spread":0.347120661684693,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004662824,0.00009018531,0.0001950233,0.00001815889,0.00008344919,0.000001866978,0.00003797387,0.00006462391,0.00001377086],"category_scores_gemma":[0.0001167265,0.00004929331,0.00002273914,0.00003032195,0.001174147,0.000003437272,0.00001599118,0.00007626929,1.005932e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":6.898712e-7,"about_ca_system_score_gemma":0.00002613283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002793152,"about_ca_topic_score_gemma":0.00002918893,"domain_scores_codex":[0.9992248,0.0000858045,0.0003353387,0.0001501019,0.0001019446,0.000101968],"domain_scores_gemma":[0.9994609,0.0001255509,0.0000768486,0.00008878542,0.00006165424,0.0001862268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003889881,0.0003332108,0.929356,0.0001925264,0.0001396658,3.123089e-7,0.002227824,5.920074e-7,0.007133792,0.02311604,0.001583265,0.03552771],"study_design_scores_gemma":[0.002388328,0.001537787,0.9574293,0.0001580663,0.00009981948,0.00001185694,0.0008350799,0.00003014035,0.0004964822,0.01391542,0.02299961,0.00009815055],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9302551,0.05764958,0.0004048586,0.01074138,0.00008115891,0.0002616706,0.00002848383,0.000003752899,0.0005739877],"genre_scores_gemma":[0.9949417,0.003210393,0.0002189123,0.0007508241,0.0007415591,0.000004092223,0.00008545065,0.000005231712,0.0000418415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06468657,"threshold_uncertainty_score":0.4326194,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3021544380","doi":"10.1002/ctm2.8","title":"Combinatorial assessment of ctDNA release and mutational burden predicts anti‐PD(L)1 therapy outcome in nonsmall‐cell lung cancer","year":2020,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Power Generation; Centre de Développement du Porc du Québec","funders":"Science and Technology Planning Project of Guangdong Province; National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Medicine; Liquid biopsy; Immunotherapy; Biomarker; Oncology; Lung cancer; Cancer; Disease; Immune checkpoint; Internal medicine; Circulating tumor cell; Targeted therapy; Bioinformatics; Metastasis; Biology","authors":[{"name":"Wenfeng Fang","is_ca":false},{"name":"Yuxiang Ma","is_ca":false},{"name":"Jiani C. Yin","is_ca":false},{"name":"Huaqiang Zhou","is_ca":false},{"name":"Fufeng Wang","is_ca":false},{"name":"Hua Bao","is_ca":true},{"name":"Ao Wang","is_ca":true},{"name":"Xue Wu","is_ca":true},{"name":"Shaodong Hong","is_ca":false},{"name":"Yunpeng Yang","is_ca":false},{"name":"Yan Huang","is_ca":false},{"name":"Hongyun Zhao","is_ca":false},{"name":"Yang Shao","is_ca":false},{"name":"Li Zhang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03750517155325412,"gpt":0.3745775224382067,"spread":0.3370723508849526,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001951842,0.00009059387,0.0002243756,0.00001947465,0.00002298411,0.000003687131,0.00005164602,0.00009287261,0.00003384162],"category_scores_gemma":[0.00009936818,0.000075137,0.00003709985,0.00005060462,0.0001990726,0.000003165888,0.00001828945,0.0001116074,1.127348e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002208967,"about_ca_system_score_gemma":0.0001335157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005801294,"about_ca_topic_score_gemma":0.00001530278,"domain_scores_codex":[0.9990684,0.000038485,0.000440584,0.0002335073,0.0001361394,0.00008286513],"domain_scores_gemma":[0.9994882,0.0001970426,0.00007933137,0.00005828347,0.00005135958,0.0001258092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002334975,0.00008586403,0.9904858,0.00006134665,0.00004124976,0.000003201442,0.00009906864,0.0002427685,0.003467007,0.001390845,0.000160819,0.00372855],"study_design_scores_gemma":[0.007956288,0.0006281472,0.9804324,0.00003883685,0.00004342362,0.000001234216,0.00002100483,0.005598462,0.0001977396,0.0008952524,0.004075104,0.0001121255],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857368,0.00419757,0.0004872596,0.00870459,0.0002533452,0.0002011053,0.00008470631,0.000002612315,0.000332028],"genre_scores_gemma":[0.992622,0.00542745,0.0002247811,0.0007478751,0.000840799,0.00001097219,0.0001119471,0.000007804376,0.000006360831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0100534,"threshold_uncertainty_score":0.3063998,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3133751538","doi":"10.1002/ctm2.337","title":"Aptamer‐SH2 superbinder‐based targeted therapy for pancreatic ductal adenocarcinoma","year":2021,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Cancer research; Pancreatic cancer; Stroma; Conjugate; Metastasis; Cancer; Immunofluorescence; Biology; Medicine; Chemistry; Pathology; Internal medicine; Antibody; Immunology; Immunohistochemistry","authors":[{"name":"Andong Liu","is_ca":false},{"name":"Jie Zhou","is_ca":false},{"name":"Xiaoyang Bi","is_ca":false},{"name":"Guoqing Hou","is_ca":false},{"name":"Shawn S.‐C. Li","is_ca":true},{"name":"Qing Chen","is_ca":false},{"name":"Hui Xu","is_ca":false},{"name":"Xuan Cao","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05681861596557435,"gpt":0.3426401445332967,"spread":0.2858215285677224,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001886556,0.0001144131,0.0002129527,0.00001878826,0.00005993012,0.000006294744,0.00006236148,0.0001285622,0.0001327327],"category_scores_gemma":[0.0001358565,0.00008806728,0.0001123201,0.00004953856,0.0002241032,0.000003220178,0.000007760791,0.00007850229,0.000002745944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":8.556275e-7,"about_ca_system_score_gemma":0.0001019115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005056891,"about_ca_topic_score_gemma":0.00001006173,"domain_scores_codex":[0.9990522,0.0000537148,0.0003278156,0.0003291366,0.000105055,0.000132053],"domain_scores_gemma":[0.9994729,0.0001196346,0.00003541447,0.0001389124,0.0001493323,0.00008384848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002178665,0.0004687918,0.7607424,0.00009325957,0.0005657974,0.00003642824,0.0001639321,0.00002590526,0.1962368,0.0006386533,0.007052522,0.03179687],"study_design_scores_gemma":[0.01152993,0.00310948,0.9261453,0.00009971207,0.0001622415,0.0000513735,0.0001932375,0.001643489,0.02616354,0.002572311,0.02793999,0.0003894729],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779406,0.01179557,0.004079855,0.005606735,0.0002369058,0.0001570705,0.00003403274,0.00000693273,0.0001422882],"genre_scores_gemma":[0.9936551,0.001038477,0.0009020863,0.002579178,0.0007938329,0.00002215937,0.0007276303,0.00001125005,0.0002702832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1700733,"threshold_uncertainty_score":0.359128,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2239976533","doi":"10.1186/s40169-015-0079-9","title":"A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brain","year":2016,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Anesthesia and Neurotoxicity Research","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Ohio State University","keywords":"Isoflurane; Medicine; Anesthesia; H&E stain; Anesthetic; Saline; Entorhinal cortex; Pharmacology; Pathology; Internal medicine; Hippocampus","authors":[{"name":"Emmett E. Whitaker","is_ca":false},{"name":"Bruno Bissonnette","is_ca":true},{"name":"Andrew D. Miller","is_ca":false},{"name":"Tanner Koppert","is_ca":false},{"name":"Joseph D. Tobias","is_ca":false},{"name":"Christopher R. Pierson","is_ca":false},{"name":"Fievos L. Christofi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2719565835437345,"gpt":0.423681281228478,"spread":0.1517246976847434,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.001506663,0.000107345,0.0002967113,0.00004419308,0.00009535081,0.000005235269,0.0002659276,0.00005145878,0.000008580878],"category_scores_gemma":[0.01352052,0.00004014441,0.00006434975,0.0002116112,0.0009432533,0.00003685638,0.00003498083,0.0001978032,0.000003421233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001682542,"about_ca_system_score_gemma":0.00007189397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003297474,"about_ca_topic_score_gemma":0.0000023106,"domain_scores_codex":[0.9977731,0.0004771858,0.0007252826,0.0002992559,0.0005795507,0.0001456884],"domain_scores_gemma":[0.9566471,0.04281257,0.0001146125,0.0002585408,0.00007573134,0.00009143279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006369499,0.004479559,0.1367566,0.0002110359,0.0001283749,0.000105845,0.004802295,0.0001475164,0.5839082,0.1720918,0.0008712364,0.09012805],"study_design_scores_gemma":[0.01463387,0.02411907,0.881111,0.002171449,0.0001879672,0.00009832491,0.0001230087,0.007128519,0.03744813,0.02955804,0.002905595,0.0005150277],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8794199,0.000007990208,0.006317765,0.1132743,0.00003719491,0.0009091499,0.00000474852,0.000007473387,0.00002147456],"genre_scores_gemma":[0.9914824,0.0000855942,0.0002807043,0.007978566,0.00004961317,0.00002786492,1.482522e-7,0.000009521276,0.00008556319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7443544,"threshold_uncertainty_score":0.994789,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4390016330","doi":"10.1002/ctm2.1507","title":"Single‐cell immune profiling reveals markers of emergency myelopoiesis that distinguish severe from mild respiratory syncytial virus disease in infants","year":2023,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Respiratory viral infections research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Medicine; Myelopoiesis; Immune system; Profiling (computer programming); Virus; Disease; Respiratory system; Immunology; Pathology; Internal medicine; Biology; Stem cell; Computer science","authors":[{"name":"Nevena Zivanovic","is_ca":false},{"name":"Deniz Öner","is_ca":false},{"name":"Yann Abraham","is_ca":false},{"name":"Joseph McGinley","is_ca":false},{"name":"Simon B. Drysdale","is_ca":true},{"name":"Joanne Wildenbeest","is_ca":false},{"name":"Marjolein Crabbe","is_ca":false},{"name":"Greet Vanhoof","is_ca":false},{"name":"Kim Thys","is_ca":false},{"name":"Ryan S. Thwaites","is_ca":false},{"name":"Hannah Robinson","is_ca":false},{"name":"Louis Bont","is_ca":false},{"name":"Peter Openshaw","is_ca":false},{"name":"Federico Martinón‐Torres","is_ca":false},{"name":"Andrew J. Pollard","is_ca":false},{"name":"Jeroen Aerssens","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1632701976011335,"gpt":0.4208058514465736,"spread":0.2575356538454401,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001501133,0.0002047358,0.0006699855,0.00033352,0.00009187114,0.000005404446,0.0001157054,0.0001702622,0.0007089092],"category_scores_gemma":[0.002633846,0.0001661628,0.0001558901,0.0007876942,0.0004182694,0.0001040984,0.00004822978,0.0004775977,0.00002226185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001842803,"about_ca_system_score_gemma":0.0001749892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001814298,"about_ca_topic_score_gemma":0.00005899683,"domain_scores_codex":[0.9968153,0.0003017272,0.001414018,0.0004852983,0.0006872775,0.00029635],"domain_scores_gemma":[0.9976568,0.001290691,0.0001874054,0.0003134823,0.0001866584,0.0003649404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002241504,0.0002902071,0.9829329,0.0002980241,0.00007933211,0.00009156507,0.0001296826,0.0000180929,0.008072272,0.00006597604,0.00054784,0.005232637],"study_design_scores_gemma":[0.003941549,0.0005188729,0.9909651,0.0006748235,0.0001048162,8.229381e-7,0.00009929296,0.0004299204,0.0005338796,0.00151406,0.001059659,0.000157169],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925957,0.002876356,0.00003437699,0.001638169,0.0005134903,0.0006002607,0.0001143635,0.00005584032,0.001571485],"genre_scores_gemma":[0.9979014,0.0006259255,0.0001489495,0.0002065598,0.0006087822,0.00003533944,0.0001903808,0.00002887761,0.0002537194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008032267,"threshold_uncertainty_score":0.7762059,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3198213221","doi":"10.1002/ctm2.510","title":"N‐Acetyl‐<scp>l</scp>‐cysteine restores reproductive defects caused by <i>Ggt1</i> deletion in mice","year":2021,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"Ovarian function and disorders","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ministry of Agriculture","funders":"Fundamental Research Funds for the Central Universities","keywords":"Cysteine; Chemistry; Andrology; Medicine; Molecular biology; Cell biology; Biology; Biochemistry; Enzyme","authors":[{"name":"Ling Wang","is_ca":true},{"name":"Jinhua Tang","is_ca":true},{"name":"Jiawei Zhou","is_ca":false},{"name":"Lihua Zhu","is_ca":true},{"name":"Feng Tan","is_ca":true},{"name":"Yaru Chen","is_ca":true},{"name":"Lei Wang","is_ca":true},{"name":"Huibin Song","is_ca":true},{"name":"Yi‐Liang Miao","is_ca":true},{"name":"Shuqi Mei","is_ca":false},{"name":"Fenge Li","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04598076579247316,"gpt":0.315629112111752,"spread":0.2696483463192788,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009831114,0.0004378351,0.001214828,0.0002554296,0.00008351211,0.00001509082,0.00009410394,0.001100774,0.0001997493],"category_scores_gemma":[0.003122554,0.0003596233,0.0002257784,0.0004835244,0.0007113642,0.00008555365,0.00002146971,0.00246343,0.00003006657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002514152,"about_ca_system_score_gemma":0.0002793515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008809649,"about_ca_topic_score_gemma":0.0000525694,"domain_scores_codex":[0.9959363,0.0003853237,0.001310992,0.001223327,0.0007544295,0.000389665],"domain_scores_gemma":[0.9962431,0.002535766,0.0002664721,0.0004089906,0.0003012999,0.0002443922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001704871,0.0002312943,0.01967722,0.000419808,0.0002076738,0.0004134368,0.0002276904,0.000002485274,0.0003516774,0.00009693584,0.9768322,0.001369116],"study_design_scores_gemma":[0.0104773,0.00104825,0.03336621,0.0009779554,0.0005627433,0.0001033626,0.0001620284,0.00004788066,0.00003822912,0.0009763575,0.9520576,0.0001820933],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03937437,0.01663717,0.0004086586,0.9336328,0.001746966,0.0009400677,0.00008842851,0.0001013387,0.007070211],"genre_scores_gemma":[0.06497568,0.00387942,0.0005189758,0.8859472,0.01653461,0.0001087746,0.009849011,0.0001552028,0.01803108],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04768554,"threshold_uncertainty_score":0.9998856,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4406255043","doi":"10.1002/ctm2.70073","title":"Lentivirus‐mediated gene therapy for Fabry disease: 5‐year End‐of‐Study results from the Canadian FACTs trial","year":2025,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Princess Margaret Cancer Centre; Hôpital Fleurimont; McMaster University; Juravinski Hospital; Western University; Dalhousie University; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada; Midwest Athletes Against Childhood Cancer","keywords":"Fabry disease; Medicine; Globotriaosylceramide; Genetic enhancement; Progenitor cell; CD34; Alpha-galactosidase; Immunology; Adverse effect; Internal medicine; Stem cell; Disease; Biology; Gene","authors":[{"name":"Dwayne L. Barber","is_ca":true},{"name":"William M. McKillop","is_ca":false},{"name":"C. Anthony Rupar","is_ca":true},{"name":"Christiane Auray‐Blais","is_ca":true},{"name":"Graeme Fraser","is_ca":true},{"name":"Daniel H. Fowler","is_ca":false},{"name":"Alexandra Berger","is_ca":true},{"name":"Ronan Foley","is_ca":true},{"name":"Armand Keating","is_ca":true},{"name":"Michael L. West","is_ca":true},{"name":"Jeffrey A. Medin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1257432147456949,"gpt":0.4180600568836499,"spread":0.2923168421379549,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001145244,0.0001361021,0.0004337219,0.0001008521,0.0001801743,0.000009686302,0.0001365175,0.0001155699,0.0001596702],"category_scores_gemma":[0.002783982,0.0000795723,0.0001269828,0.0002551536,0.0006092464,0.0000320378,0.00001166819,0.000281574,0.00000434795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001298003,"about_ca_system_score_gemma":0.0009511047,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.0163865,"about_ca_topic_score_gemma":0.02091277,"domain_scores_codex":[0.9980152,0.0001748393,0.0007544098,0.0003676084,0.0004778704,0.0002100793],"domain_scores_gemma":[0.9949397,0.004165402,0.00007498191,0.000262168,0.0002161411,0.0003415445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2180937,0.001755363,0.6730708,0.00005374575,0.001101335,0.00004408499,0.001208836,0.000002406007,0.00009470877,0.001140668,0.006010776,0.09742353],"study_design_scores_gemma":[0.1366797,0.001250937,0.842171,0.00009812743,0.0001962132,2.675909e-7,0.0001518781,0.0001830797,0.0000109237,0.002687961,0.0164957,0.00007425107],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9197472,0.003272961,0.0002064768,0.07140812,0.0004945088,0.003112661,0.0008046622,0.00001851441,0.0009348893],"genre_scores_gemma":[0.9962685,0.0003990378,0.00006457324,0.001442791,0.0006341634,0.00007028177,0.0008046635,0.00001113014,0.0003049099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1691002,"threshold_uncertainty_score":0.996953,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2771006138","doi":"10.1186/s40169-017-0174-1","title":"Post‐zygotic genomic changes in glutamate and dopamine pathway genes may explain discordance of monozygotic twins for schizophrenia","year":2017,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Ontario Mental Health Foundation; Institute for Advancements in Mental Health","keywords":"Genetics; Biology; Gene; Indel; Genome; Copy-number variation; Twin study; Monozygotic twin; Mutation; Computational biology; Single-nucleotide polymorphism; Genotype","authors":[{"name":"Christina A. Castellani","is_ca":true},{"name":"M.G. Melka","is_ca":true},{"name":"Jane L. Gui","is_ca":true},{"name":"Anthony J. Gallo","is_ca":true},{"name":"R.L. O’Reilly","is_ca":true},{"name":"Shiva M. Singh","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04456012563365783,"gpt":0.3430051002570038,"spread":0.2984449746233459,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006369598,0.0001065905,0.0003190797,0.00003297363,0.00009694091,0.000004949301,0.0000995208,0.0001164525,0.000006169334],"category_scores_gemma":[0.0005053889,0.00008282061,0.00004166146,0.00001577852,0.000448206,0.000003841791,0.0000328653,0.00006161547,3.443153e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001418164,"about_ca_system_score_gemma":0.00003512356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003849887,"about_ca_topic_score_gemma":0.0005363532,"domain_scores_codex":[0.9990578,0.00006295725,0.0004125194,0.0002724865,0.00005279235,0.0001414542],"domain_scores_gemma":[0.9992878,0.0002295399,0.0001808162,0.0001759031,0.00005521722,0.00007072338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003706157,0.00006202407,0.9062301,0.00007221799,0.0000540166,0.000001557702,0.00005325894,0.00002460404,0.04747632,0.0008128168,0.00001815884,0.04482433],"study_design_scores_gemma":[0.002680192,0.0005733111,0.9927976,0.00004537899,0.00003037416,0.00000566989,0.00003404728,0.000574698,0.0005134773,0.001914032,0.0007378588,0.0000934338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98724,0.002802428,0.001294615,0.008175456,0.0001397557,0.000214889,0.00009219377,0.000002046362,0.00003865261],"genre_scores_gemma":[0.9945032,0.001777586,0.002990447,0.0001712939,0.0003427389,0.00002236489,0.0001081591,0.000008781449,0.00007540453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08656745,"threshold_uncertainty_score":0.3377326,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3159029006","doi":"10.1002/ctm2.401","title":"Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer","year":2021,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Moncton Hospital; Mount Sinai Hospital; Sunnybrook Health Science Centre; Hôpital Maisonneuve-Rosemont; St Mary's Hospital Centre; Hôpital du Sacré-Cœur de Montréal; Hôtel-Dieu de Québec; Hôpital Charles-Le Moyne; McGill University; Dr. Georges-L.-Dumont University Hospital Centre; Jewish General Hospital","funders":"","keywords":"Colorectal cancer; Medicine; Transcriptome; Oncology; Lesion; Cancer; Internal medicine; Exact test; KRAS; Pathology; Gene; Biology; Gene expression; Genetics","authors":[{"name":"Karen Gambaro","is_ca":true},{"name":"Maud Marques","is_ca":true},{"name":"Suzan McNamara","is_ca":false},{"name":"Mathilde Couëtoux du Tertre","is_ca":false},{"name":"Zuanel Diaz","is_ca":false},{"name":"Cyrla Hoffert","is_ca":true},{"name":"Archana Srivastava","is_ca":true},{"name":"Steven Hébert","is_ca":true},{"name":"Benoît Samson","is_ca":true},{"name":"Bernard Lespérance","is_ca":true},{"name":"Yoo‐Joung Ko","is_ca":true},{"name":"Richard Dalfen","is_ca":true},{"name":"Ève St‐Hilaire","is_ca":true},{"name":"Lucas Sidéris","is_ca":true},{"name":"Félix Couture","is_ca":true},{"name":"Ronald L. Burkes","is_ca":true},{"name":"Mohammed Harb","is_ca":true},{"name":"Errol Camlioglu","is_ca":true},{"name":"Adrian Gologan","is_ca":true},{"name":"Vincent Pelsser","is_ca":true},{"name":"André Constantin","is_ca":true},{"name":"Celia M.T. Greenwood","is_ca":true},{"name":"Sabine Tejpar","is_ca":false},{"name":"Petr Kavan","is_ca":true},{"name":"Claudia L. Kleinman","is_ca":true},{"name":"Gerald Batist","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04174531645991419,"gpt":0.3522445894022599,"spread":0.3104992729423457,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002070601,0.00008261417,0.0001650781,0.00001918492,0.000053756,0.000007063683,0.00001745305,0.00004671975,0.00008689972],"category_scores_gemma":[0.0000807923,0.00005940169,0.00002180404,0.00007960717,0.0001031725,0.000004023983,0.000004895509,0.00004291426,7.647949e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005898086,"about_ca_system_score_gemma":0.0001386584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004525899,"about_ca_topic_score_gemma":0.001047464,"domain_scores_codex":[0.9992529,0.0001419485,0.0002448524,0.0002016877,0.00007200757,0.00008657837],"domain_scores_gemma":[0.9996217,0.0001639558,0.00002416479,0.00004381599,0.00006259072,0.00008376948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002024055,0.0003318753,0.9250402,0.00001431553,0.0002235964,0.00003026114,0.00119352,0.0001691441,0.06677999,0.0005665065,0.00006951468,0.003557028],"study_design_scores_gemma":[0.003886133,0.001035345,0.9852393,0.0000773756,0.00009436457,0.00003007722,0.0001919369,0.00008533079,0.005899922,0.0003465762,0.002990293,0.00012337],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923279,0.0004722408,0.0003143736,0.006524561,0.00004760425,0.0001310469,0.00008057293,0.000003046306,0.00009861218],"genre_scores_gemma":[0.9982998,0.0002837133,0.0004347251,0.0003344383,0.00006877942,0.00004090899,0.0001816876,0.000005876715,0.0003500516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06088006,"threshold_uncertainty_score":0.2422331,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2137173003","doi":"10.1186/2001-1326-2-16","title":"Application of personalized medicine to chronic disease: a feasibility assessment","year":2013,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Bridgepoint Active Healthcare; Western University; Public Health Ontario; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Pharmacogenetics; Medicine; Personalized medicine; Precision medicine; Intensive care medicine; Stroke (engine); Health care; Polypharmacy; Drug; Pharmacology; Bioinformatics; Pathology","authors":[{"name":"Ruslan Dorfman","is_ca":true},{"name":"Zayna A. Khayat","is_ca":true},{"name":"Tammy Sieminowski","is_ca":true},{"name":"Brian Golden","is_ca":true},{"name":"Renée Lyons","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2235241714160523,"gpt":0.5569070132944096,"spread":0.3333828418783573,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001427032,0.0001640391,0.0004532165,0.00007572877,0.00009199772,0.000002676804,0.000162059,0.0001221609,0.003659276],"category_scores_gemma":[0.0001879642,0.0001176261,0.00007608846,0.0001918833,0.001073812,0.00004995435,0.0000282346,0.0003570674,0.00003308876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001059672,"about_ca_system_score_gemma":0.0001155113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003632899,"about_ca_topic_score_gemma":0.000003922042,"domain_scores_codex":[0.9979759,0.0003221922,0.0008092642,0.0003714477,0.0003195631,0.0002015642],"domain_scores_gemma":[0.99784,0.0009488343,0.0001341071,0.000166823,0.0002169856,0.0006931925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005873638,0.0006090096,0.5687566,0.0002277925,0.0002227421,0.000003156759,0.0004413453,0.0001550687,0.02863836,0.02265207,0.003809032,0.3738975],"study_design_scores_gemma":[0.005599911,0.0002452473,0.8491412,0.00004128296,0.0002980181,0.000001779533,0.00002346169,0.008631654,0.0001142819,0.01472202,0.121053,0.0001280964],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8350064,0.01405685,0.01760664,0.1252469,0.001367994,0.002330598,0.0001100403,0.00005850187,0.00421609],"genre_scores_gemma":[0.9933922,0.001091719,0.0004672973,0.00356703,0.001086065,0.0001221015,0.0000724198,0.0000108367,0.0001903264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3737694,"threshold_uncertainty_score":0.9972515,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4389240153","doi":"10.1002/ctm2.1442","title":"Untargeted metabolomics identifies metabolic dysregulation of sphingolipids associated with aggressive chronic lymphocytic leukaemia and poor survival","year":2023,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Sphingolipid; Metabolomics; Lipidomics; Chronic lymphocytic leukemia; Cancer research; Sphingosine; Phenotype; Ceramide; Biology; Transcriptome; Pharmacology; Immunology; Leukemia; Apoptosis; Biochemistry; Bioinformatics; Gene; Gene expression; Receptor","authors":[{"name":"Flora Nguyen Van Long","is_ca":true},{"name":"Délya Valcourt‐Gendron","is_ca":true},{"name":"Patrick Caron","is_ca":true},{"name":"Michèle Rouleau","is_ca":true},{"name":"David Simonyan","is_ca":false},{"name":"Trang Le","is_ca":false},{"name":"Roxanne Sergerie","is_ca":true},{"name":"Isabelle Laverdière","is_ca":true},{"name":"Katrina Vanura","is_ca":false},{"name":"Chantal Guillemette","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02803405910727255,"gpt":0.3073967633995851,"spread":0.2793627042923126,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008988641,0.0001726327,0.0004854788,0.00009640207,0.00009280267,0.000009773256,0.0000829593,0.0001696497,0.00001684182],"category_scores_gemma":[0.0006276642,0.0001280039,0.00008226186,0.0002783125,0.0006246008,0.00001336536,0.00003196433,0.0001080224,0.000001095543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005116859,"about_ca_system_score_gemma":0.0002269962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000405486,"about_ca_topic_score_gemma":0.00005543954,"domain_scores_codex":[0.9985163,0.0001159191,0.0005602165,0.0003563265,0.0002578851,0.0001934055],"domain_scores_gemma":[0.9990326,0.0003033851,0.0002613474,0.0001325131,0.0001529463,0.0001172295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003123148,0.0002400362,0.4710386,0.0006113797,0.004682395,0.00004054524,0.001412691,0.004506465,0.4593243,0.01601973,0.00104288,0.03795793],"study_design_scores_gemma":[0.01016658,0.0004915908,0.9660352,0.0002773391,0.0007971652,0.00001629328,0.0001601041,0.006782377,0.01024731,0.002047582,0.00262698,0.0003514152],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988561,0.009941987,0.0004894494,0.0003968987,0.0003377477,0.0001552825,0.00004036985,0.00002219564,0.000055109],"genre_scores_gemma":[0.9952965,0.003030277,0.0001103871,0.0001049437,0.0007598071,0.000008267538,0.0005375209,0.00002000738,0.0001323014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4949967,"threshold_uncertainty_score":0.5219846,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4207066013","doi":"10.1002/ctm2.648","title":"COVID‐19 bimodal clinical and pathological phenotypes","year":2022,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Phenotype; Pathological; Medicine; Virology; Pathology; Biology; Genetics; Outbreak; Disease; Infectious disease (medical specialty)","authors":[{"name":"Sabrina Setembre Batah","is_ca":false},{"name":"Maíra Nilson Benatti","is_ca":false},{"name":"Li Siyuan","is_ca":false},{"name":"W. Telini","is_ca":false},{"name":"Jamile O. Barboza","is_ca":false},{"name":"Marcelo Bezerra de Menezes","is_ca":false},{"name":"Tales Rubens de Nadai","is_ca":false},{"name":"Keyla Santos Guedes de Sá","is_ca":false},{"name":"Chirag M. Vaswani","is_ca":true},{"name":"Sahil Gupta","is_ca":true},{"name":"Dario S. Zamboni","is_ca":false},{"name":"Danilo Tadao Wada","is_ca":false},{"name":"Rodrigo T. Calado","is_ca":false},{"name":"Renê Donizeti Ribeiro de Oliveira","is_ca":false},{"name":"Paulo Louzada‐Júnior","is_ca":false},{"name":"Maria Auxiliadora‐Martins","is_ca":false},{"name":"Flávio P. Veras","is_ca":false},{"name":"Larissa D. Cunha","is_ca":false},{"name":"Thiago M. Cunha","is_ca":false},{"name":"Rodrigo Luppino Assad","is_ca":false},{"name":"Marcelo Luiz Balancin","is_ca":false},{"name":"Sirlei Siani Moráis","is_ca":false},{"name":"Ronaldo B. Martins","is_ca":false},{"name":"Eurico Arruda","is_ca":false},{"name":"Fernando Chahud","is_ca":false},{"name":"Marcel Koenigkam Santos","is_ca":false},{"name":"Andrea Antunes Cetlin","is_ca":false},{"name":"Fernando Q. Cunha","is_ca":false},{"name":"Claúdia C. dos Santos","is_ca":true},{"name":"Vera Luíza Capelozzi","is_ca":false},{"name":"Junya Fukuoka","is_ca":false},{"name":"Rosane Duarte Achcar","is_ca":false},{"name":"Alexandre Todorovic Fabro","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2224275093143757,"gpt":0.5065171687782769,"spread":0.2840896594639012,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.006004594,0.0005857036,0.00257754,0.0002505778,0.0004166478,0.00002070701,0.0002891875,0.001436452,0.006002639],"category_scores_gemma":[0.08306709,0.0003937198,0.0005503409,0.0003147762,0.007818194,0.00005889839,0.0003517376,0.007711795,0.0000323258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003325746,"about_ca_system_score_gemma":0.00127552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006151896,"about_ca_topic_score_gemma":0.000006848986,"domain_scores_codex":[0.9918218,0.001289781,0.002774206,0.00175058,0.001711612,0.0006520469],"domain_scores_gemma":[0.9386823,0.05849963,0.0003495812,0.0005877175,0.0002412209,0.001639603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002387187,0.0004908475,0.3252453,0.001744959,0.0007523192,0.003732658,0.000133864,0.000002225422,0.000001421066,0.0008856688,0.6208785,0.0437451],"study_design_scores_gemma":[0.007072507,0.003530697,0.1782854,0.0001712907,0.0007167516,0.00006392999,0.00001905666,0.0001689847,3.52445e-8,0.01355074,0.7961048,0.0003157851],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003499971,0.004395505,0.000503137,0.9880674,0.0009728341,0.001041261,0.0002463723,0.0001388821,0.001134574],"genre_scores_gemma":[0.03667274,0.01486478,0.000721542,0.9292381,0.01490368,0.0001119943,0.0009898636,0.00006796404,0.002429344],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1752264,"threshold_uncertainty_score":0.9998599,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4293473771","doi":"10.1002/ctm2.1035","title":"Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies","year":2022,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Base excision repair; Medicine; Control (management); Base (topology); DNA repair; Computer science; Biology; Genetics; DNA; Artificial intelligence","authors":[{"name":"Carlos Benitéz‐Buelga","is_ca":false},{"name":"Thomas Helleday","is_ca":false},{"name":"Maurice Michel","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03895704267273664,"gpt":0.320112041916222,"spread":0.2811549992434854,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003363076,0.00007401746,0.0002092437,0.00002780286,0.00003351104,0.000001175787,0.00003107785,0.00004948775,0.00007279767],"category_scores_gemma":[0.0000829389,0.00005573679,0.00006352593,0.00003421397,0.0001546439,0.000003584345,0.000013059,0.00004362507,1.070981e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001622383,"about_ca_system_score_gemma":0.00008600025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002155149,"about_ca_topic_score_gemma":0.0000080011,"domain_scores_codex":[0.9991597,0.00008236439,0.0003746674,0.000189718,0.0001385275,0.00005505732],"domain_scores_gemma":[0.9995277,0.0001774479,0.00009261008,0.0001054811,0.00003682308,0.00005995456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004481751,0.001045405,0.1165991,0.0002075534,0.0006492916,0.00001239058,0.0007997808,0.0004561104,0.7630043,0.01382197,0.0003378586,0.09858447],"study_design_scores_gemma":[0.05306599,0.04580386,0.6797686,0.000386166,0.001643621,0.0001509396,0.002878634,0.008689915,0.1131054,0.0745557,0.01907159,0.0008795517],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940281,0.001942293,0.002418929,0.001148029,0.00007497809,0.0001649173,0.00003323114,0.00000630578,0.000183215],"genre_scores_gemma":[0.9989333,0.0002641219,0.0004664059,0.0001028677,0.0001015292,0.000008886824,0.00005992576,0.00000547918,0.00005754354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6498989,"threshold_uncertainty_score":0.2272881,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4409241280","doi":"10.1002/ctm2.70298","title":"MiR‐146a engineered extracellular vesicles derived from mesenchymal stromal cells more potently attenuate ischaemia–reperfusion injury in lung transplantation","year":2025,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital; University Health Network","funders":"National Key Research and Development Program of China","keywords":"Inflammasome; Mesenchymal stem cell; Medicine; Reperfusion injury; Microvesicles; Inflammation; Exosome; Extracellular vesicle; Lung; Proinflammatory cytokine; Transplantation; Cancer research; Immunology; Ischemia; microRNA; Chemistry; Pathology; Internal medicine","authors":[{"name":"Xiucheng Yang","is_ca":false},{"name":"Shanchao Hong","is_ca":false},{"name":"Tao Yan","is_ca":false},{"name":"Mingzhao Liu","is_ca":true},{"name":"Mingyao Liu","is_ca":true},{"name":"Jin Zhao","is_ca":false},{"name":"Bingqing Yue","is_ca":false},{"name":"Di Wu","is_ca":false},{"name":"Jing‐Bo Shao","is_ca":false},{"name":"Man Huang","is_ca":false},{"name":"Jingyu Chen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02947048768543227,"gpt":0.3588895458106066,"spread":0.3294190581251743,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006579653,0.000267533,0.0006934485,0.0002291102,0.00008754614,0.00001044844,0.00008828646,0.0002665146,0.000186266],"category_scores_gemma":[0.00008710573,0.0002096641,0.0001483118,0.0002870728,0.0003154279,0.0001249823,0.00000809449,0.0004905179,0.000003893663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001197291,"about_ca_system_score_gemma":0.0001080416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001401774,"about_ca_topic_score_gemma":0.0000319825,"domain_scores_codex":[0.9975435,0.0001813857,0.001117796,0.0005166089,0.0003870836,0.0002536724],"domain_scores_gemma":[0.9983613,0.001077231,0.00009321611,0.0001809556,0.00008531432,0.0002019656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004380572,0.0003834601,0.5768057,0.0007298506,0.0002986916,0.00039651,0.002201156,0.0001132994,0.3683243,0.001370033,0.0001265584,0.04486983],"study_design_scores_gemma":[0.009231364,0.0002227366,0.9707158,0.001060458,0.000648976,0.00001745875,0.000177555,0.004744956,0.01151716,0.001218697,0.0002449101,0.0001999818],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9558225,0.002720385,0.02610682,0.01400253,0.0005256713,0.0004921234,0.0001202134,0.00005453803,0.0001551801],"genre_scores_gemma":[0.9845212,0.00171278,0.01181986,0.0008191335,0.0003388465,0.00001777881,0.0005637133,0.00001916517,0.000187518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3939101,"threshold_uncertainty_score":0.8549852,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3099426483","doi":"10.1002/ctm2.209","title":"Head and neck cancer: Emerging concepts in biomarker discovery and opportunities for clinical translation","year":2020,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Medicine; Head and neck cancer; Radiation therapy; Cancer; Watchful waiting; Biomarker; Oncology; Intensive care medicine; Internal medicine; Prostate cancer","authors":[{"name":"Luiz Paulo Kowalski","is_ca":false},{"name":"Ricardo D. Coletta","is_ca":false},{"name":"Tuula Salo","is_ca":false},{"name":"Mariana Maschietto","is_ca":false},{"name":"Rubens Chojniak","is_ca":false},{"name":"Jefferson Muniz de Lima","is_ca":true},{"name":"Alex Mlynarek","is_ca":true},{"name":"Michael Hier","is_ca":true},{"name":"Moulay A. Alaoui‐Jamali","is_ca":true},{"name":"Sabrina Daniela da Silva","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3549773045546623,"gpt":0.4870270505439243,"spread":0.1320497459892619,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006599097,0.0003446023,0.001582451,0.0001240531,0.000106486,0.00001649995,0.0000479795,0.00051422,0.00003905577],"category_scores_gemma":[0.0002358302,0.0002588618,0.0001576826,0.00009583212,0.001442337,0.0001337736,0.00001846733,0.00107244,3.312374e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007696854,"about_ca_system_score_gemma":0.0002217315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006397314,"about_ca_topic_score_gemma":0.00008461149,"domain_scores_codex":[0.9970489,0.0001598947,0.001467256,0.0007180588,0.0003235798,0.0002822674],"domain_scores_gemma":[0.9966534,0.00273309,0.0001725308,0.0001134741,0.00008903866,0.0002384601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002069205,0.00009430241,0.2227312,0.002342654,0.0005632954,0.000311214,0.0008375614,1.680364e-7,0.000006878123,0.0001826687,0.2647074,0.5061535],"study_design_scores_gemma":[0.01194182,0.001214962,0.2312925,0.002422306,0.000605792,0.00002427854,0.0001188519,0.000671874,3.970674e-7,0.001064296,0.7503587,0.0002842641],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03673144,0.04386996,0.0002169308,0.9170868,0.0006387717,0.000807256,0.0002350168,0.00002811578,0.0003856756],"genre_scores_gemma":[0.1115304,0.1599104,0.0007130298,0.7166576,0.009253499,0.0001811056,0.001007312,0.00007703093,0.0006696367],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.5058693,"threshold_uncertainty_score":0.9999864,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4403378263","doi":"10.1002/ctm2.70018","title":"Dietary fibre and metabolic health: A clinical primer","year":2024,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Diet and metabolism studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Weston Family Foundation","keywords":"Dietary fibre; Medicine; Health benefits; Obesity; Health care; Human nutrition; Intensive care medicine; Biotechnology; Food science; Biology; Internal medicine; Pathology; Traditional medicine","authors":[{"name":"Valentin Mocanu","is_ca":false},{"name":"Karen Madsen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1499130888929063,"gpt":0.4563181112206219,"spread":0.3064050223277156,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001447823,0.000177944,0.00091245,0.00008687485,0.00008845635,0.00001018568,0.00003447954,0.0001226165,0.0001271585],"category_scores_gemma":[0.0003206891,0.000110651,0.0001606126,0.0001701898,0.0009950041,0.00007523975,0.0000245943,0.0004542179,0.00001999784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001286763,"about_ca_system_score_gemma":0.0001481621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002301506,"about_ca_topic_score_gemma":0.00000782707,"domain_scores_codex":[0.997932,0.0001104765,0.001007098,0.0004615745,0.0002790908,0.0002097869],"domain_scores_gemma":[0.9981833,0.001140133,0.00005046391,0.0001288752,0.000060484,0.0004368032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0002797404,0.0001550437,0.1944645,0.000361507,0.0005182191,0.00004035137,0.0005078538,5.841681e-8,0.00001585388,0.009021806,0.01092083,0.7837142],"study_design_scores_gemma":[0.001841181,0.0005042697,0.6793094,0.0003571733,0.000388687,0.00002845753,0.00004235369,0.0001416781,7.807964e-7,0.003104422,0.3142043,0.00007731764],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2680915,0.4625601,0.0002430906,0.2608275,0.002735052,0.0006089516,0.00003462335,0.0001735659,0.004725615],"genre_scores_gemma":[0.9191334,0.06591422,0.001718489,0.007711492,0.004054607,0.00001453112,0.00006690631,0.00002553397,0.001360824],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.7836369,"threshold_uncertainty_score":0.4512219,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4392366622","doi":"10.1002/ctm2.1595","title":"Analysis of single nuclear chromatin accessibility reveals unique myeloid populations in human pancreatic ductal adenocarcinoma","year":2024,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of General Medical Sciences; National Cancer Institute; West Virginia Clinical and Translational Science Institute; National Institutes of Health; National Science Foundation","keywords":"Pancreatic ductal adenocarcinoma; Chromatin; Medicine; Biology; Cancer research; Internal medicine; Pancreatic cancer; Genetics; Gene; Cancer","authors":[{"name":"Hillary G. Pratt","is_ca":false},{"name":"Li Ma","is_ca":false},{"name":"Sebastian A. Dziadowicz","is_ca":false},{"name":"Sascha Ott","is_ca":false},{"name":"Thomas Whalley","is_ca":false},{"name":"Barbara Szomolay","is_ca":true},{"name":"Timothy D. Eubank","is_ca":false},{"name":"Gangqing Hu","is_ca":false},{"name":"Brian A. Boone","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08552564642485463,"gpt":0.3709104098727944,"spread":0.2853847634479398,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004670715,0.0001088424,0.0003547563,0.00013552,0.00004272198,0.000009410178,0.00008298754,0.0001406061,0.0001036401],"category_scores_gemma":[0.0001033142,0.00008858258,0.0001342198,0.0003575333,0.0003222493,0.000008129689,0.00001258041,0.0001221205,5.357864e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003976898,"about_ca_system_score_gemma":0.00002828016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000885419,"about_ca_topic_score_gemma":0.0002095914,"domain_scores_codex":[0.9986188,0.0001099774,0.0007085396,0.0003327403,0.0001263026,0.0001035734],"domain_scores_gemma":[0.9995585,0.0001109482,0.00005711478,0.000154233,0.00004503482,0.00007416173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006600757,0.0001557319,0.8061787,0.00009530691,0.0002568973,0.000005166994,0.0001682694,0.00003803215,0.1902798,0.001621553,0.00003074645,0.001103778],"study_design_scores_gemma":[0.0005751328,0.0003038961,0.9937372,0.0001145362,0.0004585915,0.000003208782,0.00002604759,0.001821977,0.0003465182,0.002389594,0.0001268532,0.0000964204],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956036,0.002149075,0.0007985751,0.0008006216,0.0001077136,0.0001237079,0.00003725897,0.00001176848,0.0003676637],"genre_scores_gemma":[0.9987193,0.00009932848,0.0004498129,0.0001044656,0.0001964,0.000003544944,0.0003636866,0.00001122905,0.00005223523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1899332,"threshold_uncertainty_score":0.3612293,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4296799460","doi":"10.1002/ctm2.1033","title":"Orally‐administrated mitochondria attenuate pulmonary hypertension with the aid of erythrocytes as carriers","year":2022,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Natural Science Foundation of China","keywords":"Medicine; Mitochondrion; Pulmonary hypertension; Pharmacology; Internal medicine; Chemistry; Biochemistry","authors":[{"name":"Rui Xiao","is_ca":false},{"name":"Jie Liu","is_ca":false},{"name":"Shengquan Luo","is_ca":false},{"name":"Zhe Yu","is_ca":false},{"name":"Jiwei Zhang","is_ca":false},{"name":"Yan-Kai Lv","is_ca":false},{"name":"Jiansha Li","is_ca":false},{"name":"Matthieu Ruiz","is_ca":true},{"name":"Jocelyn Dupuis","is_ca":true},{"name":"Qinghua Hu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03665502706832312,"gpt":0.2967556111101591,"spread":0.260100584041836,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002981755,0.0002576355,0.0004872536,0.00004823523,0.000144146,0.000005176015,0.0001861514,0.0005276041,0.0006722186],"category_scores_gemma":[0.0001407558,0.0001501329,0.0001343998,0.0001149793,0.001141795,0.000003022292,0.00003749278,0.0009105177,0.000004394981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001957955,"about_ca_system_score_gemma":0.0002104712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002692591,"about_ca_topic_score_gemma":0.00001699568,"domain_scores_codex":[0.9980469,0.0003136698,0.0005624628,0.0005412354,0.0003487642,0.0001869209],"domain_scores_gemma":[0.9988597,0.0003499666,0.0002293647,0.0003193966,0.0001556251,0.00008594688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003740958,0.0001022959,0.00408793,0.0001449902,0.0005028109,0.0004990083,0.00007864281,0.00001963745,0.01576518,0.0001238824,0.9726751,0.002259512],"study_design_scores_gemma":[0.001692653,0.00265185,0.001457133,0.0000567405,0.0002674953,0.0004762645,0.00007046825,0.00001797776,0.0001802095,0.0002469236,0.9926738,0.0002085398],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.06304866,0.003459786,0.000313117,0.9276902,0.001918123,0.0006607222,0.0002289062,0.00002015055,0.002660317],"genre_scores_gemma":[0.1819109,0.002464361,0.0007273985,0.776029,0.01538204,0.0001378025,0.01195739,0.0001329498,0.01125817],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1516612,"threshold_uncertainty_score":0.7360322,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3108705866","doi":"10.1002/ctm2.237","title":"Combinational therapy targeting the MET‐mTOR‐ROS loop disrupts mitochondrial autoregulatory machinery of liver cancer","year":2020,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pancreas Centre (Canada)","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"PI3K/AKT/mTOR pathway; Cancer research; Autophosphorylation; Oxidative phosphorylation; Mitochondrion; Cell biology; mTORC2; Mechanistic target of rapamycin; Phosphorylation; Biology; Chemistry; Signal transduction; mTORC1; Biochemistry; Protein kinase A","authors":[{"name":"Xing Huang","is_ca":true},{"name":"Gang Zhang","is_ca":true},{"name":"Xueli Bai","is_ca":true},{"name":"Tingbo Liang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04817615481048524,"gpt":0.3411646388028844,"spread":0.2929884839923992,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003657709,0.0003198291,0.0005489882,0.00003978334,0.0001147786,0.00001013961,0.0003214972,0.0005876663,0.0004027328],"category_scores_gemma":[0.0002388107,0.0002069612,0.0002597422,0.00009485117,0.001202511,0.000005771391,0.00004453235,0.0009182303,0.000002293261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006820344,"about_ca_system_score_gemma":0.0002819589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004469792,"about_ca_topic_score_gemma":0.000005897297,"domain_scores_codex":[0.9974515,0.0002867427,0.0008578175,0.0005907575,0.0005987377,0.0002144792],"domain_scores_gemma":[0.9984508,0.000645637,0.0003489937,0.0002419951,0.0002158089,0.00009680832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005665825,0.0001118749,0.01177501,0.0002362064,0.001057668,0.00003741787,0.0001685965,0.00006339126,0.03306166,0.0002509627,0.9347263,0.01794431],"study_design_scores_gemma":[0.004802178,0.0009470343,0.01951508,0.0002698034,0.0003155787,0.00001142356,0.000007637895,0.000749969,0.001208397,0.001782508,0.9699001,0.000490258],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.08183762,0.05999697,0.0009934629,0.8495505,0.005358039,0.001064155,0.0008197143,0.00004155251,0.0003379233],"genre_scores_gemma":[0.4779932,0.006542405,0.0008909955,0.4458862,0.06282644,0.0001713846,0.004406469,0.0001525427,0.001130432],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4036644,"threshold_uncertainty_score":0.8439633,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4309514213","doi":"10.1002/ctm2.949","title":"When the clock ticks wrong with COVID‐19","year":2022,"lang":"en","type":"review","venue":"Clinical and Translational Medicine","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; University of Saskatchewan","funders":"Saskatchewan Health Research Foundation","keywords":"Circadian rhythm; Disease; Circadian clock; Medicine; Asymptomatic; Coronavirus disease 2019 (COVID-19); Immune system; Immunology; Infectious disease (medical specialty); Bioinformatics; Biology; Internal medicine","authors":[{"name":"Silvana Papagerakis","is_ca":true},{"name":"Raed Said","is_ca":true},{"name":"Farinaz Ketabat","is_ca":true},{"name":"Razi Mahmood","is_ca":true},{"name":"Meenakshi Pundir","is_ca":true},{"name":"Liubov Lobanova","is_ca":true},{"name":"Greg Guenther","is_ca":true},{"name":"Giuseppe Pannone","is_ca":false},{"name":"Kerry J. Lavender","is_ca":true},{"name":"Blake McAlpin","is_ca":false},{"name":"Alain Moreau","is_ca":true},{"name":"Daniel Chen","is_ca":true},{"name":"Pétros Papagerakis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2767300641194041,"gpt":0.4314867386777292,"spread":0.1547566745583251,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008857657,0.0002607076,0.0009508241,0.00006945962,0.0003385865,0.00001514266,0.0002620074,0.0001514016,0.002886678],"category_scores_gemma":[0.001401451,0.0001261363,0.0001945241,0.0002380001,0.001242343,0.0000411305,0.0000334044,0.0009581582,0.0000296418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001088961,"about_ca_system_score_gemma":0.0005988778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006167262,"about_ca_topic_score_gemma":0.000004513765,"domain_scores_codex":[0.9974253,0.000498582,0.0007808489,0.000588238,0.0004962887,0.0002107759],"domain_scores_gemma":[0.9906439,0.008398345,0.0002115577,0.0002788016,0.00001123291,0.000456145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004045717,0.00005195299,0.0001630574,0.001390642,0.0000455576,0.0001159632,0.0002472776,0.000001551238,6.860797e-8,0.06512748,0.001408999,0.931407],"study_design_scores_gemma":[0.0008183572,0.0001915726,0.0001067785,0.0007722597,0.0004814483,0.0004563598,0.000012484,0.00001274589,6.903382e-8,0.001809824,0.995174,0.0001641191],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001176476,0.9856443,0.000183553,0.009134251,0.0004691047,0.0006490914,0.00007074188,0.00003714091,0.003800047],"genre_scores_gemma":[0.0002035789,0.9932454,0.00003516767,0.004138769,0.0009092054,0.00008024832,0.00005876274,0.00002831869,0.001300581],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.993765,"threshold_uncertainty_score":0.9980248,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4318465082","doi":"10.1002/ctm2.1169","title":"Conclusions of the SIGNAL study in Huntington and implications for treatment of other slowly progressive neurodegenerative diseases","year":2023,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Huntington's disease; Medicine; Neuroscience; Disease; Psychology; Internal medicine","authors":[{"name":"Maurice Zauderer","is_ca":false},{"name":"Elizabeth E. Evans","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1369446113474179,"gpt":0.4236685761025875,"spread":0.2867239647551696,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001005281,0.00008949503,0.000245321,0.00005274076,0.00009919867,0.000002797684,0.00006858164,0.00002002945,0.00001168814],"category_scores_gemma":[0.0004693663,0.00005174908,0.00005385759,0.0002499768,0.0006664093,0.00002193854,0.00002100879,0.00002718275,1.804483e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001485485,"about_ca_system_score_gemma":0.00005460219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006496856,"about_ca_topic_score_gemma":0.00001408003,"domain_scores_codex":[0.9988764,0.0002076625,0.0004142778,0.0002849092,0.0001298897,0.00008687881],"domain_scores_gemma":[0.9974723,0.002183188,0.0001116555,0.0001110526,0.00006121339,0.00006059351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001230129,0.000814793,0.960663,0.00001818618,0.00001335552,6.509255e-7,0.000746348,0.00008775994,0.02846825,0.002987169,0.00002140701,0.006056036],"study_design_scores_gemma":[0.002510019,0.001138105,0.9819058,0.00002866661,0.00007759613,5.011493e-7,0.00008192683,0.0005171555,0.009885111,0.003763811,0.00004679738,0.00004449277],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932334,0.0002172515,0.00005673612,0.004983786,0.00006202116,0.001113477,0.0003026453,0.000008281452,0.00002241384],"genre_scores_gemma":[0.9995028,0.00005638986,0.0000345074,0.0001573074,0.00006740859,0.0001374708,0.000006877191,0.000007330414,0.00002991308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02124278,"threshold_uncertainty_score":0.2455413,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4411465227","doi":"10.1002/ctm2.70369","title":"Splicing to keep splicing: A feedback system for cellular homeostasis and state transition","year":2025,"lang":"en","type":"review","venue":"Clinical and Translational Medicine","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Key Research and Development Projects of Shaanxi Province; National Natural Science Foundation of China","keywords":"RNA splicing; Alternative splicing; microRNA; Biology; Computational biology; Spliceosome; Gene isoform; Gene; Genetics; RNA","authors":[{"name":"Zhonghao Guo","is_ca":false},{"name":"Xurui Zhang","is_ca":false},{"name":"Yachen Li","is_ca":true},{"name":"Yule Chen","is_ca":false},{"name":"Yungang Xu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06214383765218297,"gpt":0.3966889949260184,"spread":0.3345451572738355,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009222894,0.00031745,0.00118484,0.0001277386,0.0001384079,0.00002172307,0.0001278698,0.0003079728,0.000004699715],"category_scores_gemma":[0.0002022813,0.0002387968,0.0002542853,0.0001761135,0.0001890279,0.00000440728,0.00003517807,0.0002361906,0.000002205491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007740628,"about_ca_system_score_gemma":0.0001705963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000216395,"about_ca_topic_score_gemma":0.00001804334,"domain_scores_codex":[0.9977444,0.0001493729,0.0009156367,0.0006932309,0.0002017819,0.0002956111],"domain_scores_gemma":[0.9986834,0.0005331545,0.0001164679,0.0002196205,0.0001183416,0.0003290047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001836656,0.00002789307,0.00002121428,0.01769495,0.0002227553,0.000005547317,0.00003355576,0.000003968052,0.0002936934,0.0001773875,0.0002615464,0.9810738],"study_design_scores_gemma":[0.003773499,0.00172899,0.0001595368,0.0295286,0.001326798,0.00004793996,0.00009356136,0.0002957116,0.0001058897,0.0002984751,0.961987,0.0006539623],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002776745,0.9739013,0.02024343,0.00110662,0.0001818054,0.001444282,0.0002340398,0.00001503329,0.00009677804],"genre_scores_gemma":[0.002496708,0.9943717,0.0006712398,0.0002571789,0.000739796,0.0001308189,0.0007501296,0.00003288372,0.0005495527],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9804199,"threshold_uncertainty_score":0.9737851,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2131861212","doi":"10.1186/2001-1326-3-11","title":"Overcoming the translational roadblocks: a cancer care and research model","year":2014,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Health and Medical Research Impacts","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"BC Cancer Foundation; Michael Smith Health Research BC; BC Cancer Agency; Victoriastiftelsen","keywords":"Translational research; Participatory action research; Process (computing); Citizen journalism; Engineering ethics; Medicine; Translational science; Knowledge management; Process management; Computer science; Sociology; Engineering","authors":[{"name":"Lauren Braun","is_ca":true},{"name":"Helena ML Daudt","is_ca":true},{"name":"Peter H. Watson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.4091168154477111,"gpt":0.5706480987106818,"spread":0.1615312832629707,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.004696026,0.0001264774,0.0003690662,0.0001024412,0.0003148169,0.00001122692,0.00007621924,0.0001594141,0.0001620879],"category_scores_gemma":[0.008852272,0.0000667527,0.00005765005,0.0002086557,0.00153335,0.00006020759,0.00001793167,0.0009677108,0.000004150998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001105501,"about_ca_system_score_gemma":0.00124781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001428191,"about_ca_topic_score_gemma":0.00005787559,"domain_scores_codex":[0.9971758,0.0002814884,0.0005297108,0.0003310307,0.001171927,0.0005100791],"domain_scores_gemma":[0.9932151,0.004036805,0.00003462505,0.0001654186,0.0003521172,0.002195863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001144385,0.0001283155,0.1463532,0.0006747996,0.00008925171,0.00001029976,0.003400156,0.00005376943,0.0001441601,0.01192981,0.009200246,0.8268716],"study_design_scores_gemma":[0.01641411,0.002305234,0.4965669,0.001757035,0.0002370672,0.00006936708,0.0007442179,0.1645713,0.00002030712,0.03254187,0.2845136,0.0002590002],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.3697232,0.01303522,0.004663692,0.601784,0.0001872496,0.0009405816,0.00003036316,0.00003550909,0.009600235],"genre_scores_gemma":[0.9856331,0.00263031,0.0007537239,0.008936207,0.001697371,0.00003933882,0.00003020545,0.00001370632,0.000265973],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8266126,"threshold_uncertainty_score":0.9994966,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2948151014","doi":"10.1186/s40169-019-0236-7","title":"The use of leukocytes’ secretome to individually target biological therapy in autoimmune arthritis: a case report","year":2019,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"Fondation du Grand défi Pierre Lavoie; Fondation CHU de Québec; Rare Disease Foundation","keywords":"Medicine; Immunology; Arthritis; Rheumatoid arthritis","authors":[{"name":"Patrice E. Poubelle","is_ca":true},{"name":"Nathalie Pagé","is_ca":true},{"name":"Marie‐Pier Longchamps","is_ca":true},{"name":"Natalia Sampaio Moura","is_ca":false},{"name":"David B. Beck","is_ca":false},{"name":"Ivona Aksentijevich","is_ca":false},{"name":"Philippe A. Tessier","is_ca":true},{"name":"Martin Pelletier","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1310021715401851,"gpt":0.3707765590583516,"spread":0.2397743875181665,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006901249,0.00014059,0.0005813535,0.00006554967,0.0000740612,0.00000610236,0.00004274823,0.0001082333,0.0001848978],"category_scores_gemma":[0.000470528,0.00007584196,0.00009161712,0.0002023516,0.0004133976,0.00004362782,0.00002207045,0.000212565,0.000008470379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005311801,"about_ca_system_score_gemma":0.00006363905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001139422,"about_ca_topic_score_gemma":0.0000786191,"domain_scores_codex":[0.9982392,0.00008231172,0.0009283766,0.0003046596,0.0002549223,0.0001905401],"domain_scores_gemma":[0.9980964,0.00134783,0.0001067046,0.0002102204,0.0001041287,0.0001347264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001201883,0.0002725504,0.9096176,0.00000961382,0.0001814423,0.007036114,0.0003029592,0.000006416385,0.00007224949,0.0005907713,0.0001377217,0.08057065],"study_design_scores_gemma":[0.009685754,0.002685155,0.9543921,0.0002937443,0.00001811776,0.004660573,0.0001186593,0.00005596944,0.000009367457,0.0007030044,0.02729118,0.00008638473],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817252,0.007916629,0.0000356748,0.009100359,0.0002396397,0.0007262486,0.00002455399,0.00001560716,0.0002161185],"genre_scores_gemma":[0.9932722,0.004607594,0.0009521563,0.0007843291,0.0001208757,0.0000317878,0.0000674277,0.000009165547,0.0001544807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08048427,"threshold_uncertainty_score":0.3092746,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4404977496","doi":"10.1002/ctm2.70086","title":"Extracellular vesicles derived from creeping fat stem cells promote lymphatic function and restrain inflammation of Crohn's disease","year":2024,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre","funders":"National Natural Science Foundation of China","keywords":"Lymphangiogenesis; Lymphatic system; Inflammation; Medicine; Lymphatic Endothelium; Tumor necrosis factor alpha; Cancer research; Pathology; Immunology; Internal medicine; Cancer; Metastasis","authors":[{"name":"Weigang Shu","is_ca":false},{"name":"Yongheng Wang","is_ca":false},{"name":"Mengfan Chen","is_ca":false},{"name":"Xiaoli Zhu","is_ca":false},{"name":"Fangtao Wang","is_ca":false},{"name":"Chunqiu Chen","is_ca":false},{"name":"Peng Du","is_ca":false},{"name":"Alexandra Bartolomucci","is_ca":true},{"name":"Xin Su","is_ca":true},{"name":"Xiaolei Wang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0506065329913267,"gpt":0.3131907621173515,"spread":0.2625842291260247,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003855246,0.0001453942,0.0003859523,0.00008595463,0.00005205485,0.00001716472,0.00003002779,0.00008637031,0.0001098959],"category_scores_gemma":[0.0001177475,0.0001046863,0.00008323915,0.0001127877,0.0003775767,0.0001314114,0.000008917495,0.00003747495,0.000005670143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006345546,"about_ca_system_score_gemma":0.0001191285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002117072,"about_ca_topic_score_gemma":0.000002369188,"domain_scores_codex":[0.9983316,0.0001028495,0.0007846154,0.0003347947,0.0003351549,0.0001109684],"domain_scores_gemma":[0.9984676,0.0009137805,0.00009181653,0.000132541,0.00006897954,0.000325298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.004676158,0.000475394,0.2158818,0.007187647,0.0009273024,0.0006679364,0.001989637,0.00002946394,0.134279,0.01100789,0.0002241712,0.6226536],"study_design_scores_gemma":[0.004037382,0.0002897618,0.9673086,0.003295725,0.001172304,0.000008884754,0.0001888481,0.009526193,0.000757173,0.01289685,0.0003848836,0.0001333876],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9564666,0.033039,0.006018035,0.003546795,0.0003066437,0.0004599208,0.00003985569,0.0000551613,0.00006804846],"genre_scores_gemma":[0.9981582,0.0003663313,0.0003091003,0.00008651186,0.00083256,0.00001377895,0.0001046685,0.00001522615,0.0001136932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7514268,"threshold_uncertainty_score":0.4268982,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4221124240","doi":"10.1002/ctm2.749","title":"Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer","year":2022,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Genetics","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; National Natural Science Foundation of China","keywords":"Phosphoproteomics; Phosphoprotein; Phosphorylation; Proteome; Myeloid leukaemia; Medicine; Phosphopeptide; Cancer research; Myeloid; Molecular biology; Bioinformatics; Biology; Protein phosphorylation; Cell biology; Protein kinase A","authors":[{"name":"Yinghui Zhu","is_ca":false},{"name":"Xin He","is_ca":false},{"name":"Shu Li","is_ca":false},{"name":"Yichao Gan","is_ca":true},{"name":"Zheng Li","is_ca":false},{"name":"Hanying Wang","is_ca":false},{"name":"Haojie Dong","is_ca":false},{"name":"Lei Zhang","is_ca":false},{"name":"Shengli Xue","is_ca":false},{"name":"Yang Xu","is_ca":false},{"name":"Ling Li","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0308051641331381,"gpt":0.3308185179120876,"spread":0.3000133537789495,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001804253,0.000628505,0.001587465,0.0002694783,0.000432936,0.00005159263,0.0002731558,0.001106373,0.0008443373],"category_scores_gemma":[0.0006987337,0.0005299912,0.0002296215,0.0005213722,0.00142069,0.0001583201,0.0001851741,0.005550819,0.0000172101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001378234,"about_ca_system_score_gemma":0.0009582404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001063247,"about_ca_topic_score_gemma":0.000004183139,"domain_scores_codex":[0.9945859,0.0002733162,0.001729555,0.001289188,0.001372642,0.0007493433],"domain_scores_gemma":[0.9969847,0.001262573,0.0005475782,0.0004450844,0.0003114355,0.0004485962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02785728,0.0005001914,0.3076302,0.006852629,0.006983162,0.01593379,0.001662862,0.0001801022,0.004140531,0.004230462,0.5035875,0.1204413],"study_design_scores_gemma":[0.05438939,0.006989761,0.3579538,0.007220256,0.008952503,0.00400747,0.0003390471,0.006008866,0.001132234,0.05573569,0.4934638,0.003807219],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.3838462,0.01407093,0.0004730839,0.5963268,0.0007942969,0.003135349,0.0001791538,0.0001640868,0.001010037],"genre_scores_gemma":[0.4518055,0.01596388,0.01001918,0.4901716,0.02121387,0.0007121068,0.006376581,0.0003290204,0.003408262],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1166341,"threshold_uncertainty_score":0.9997151,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3116928873","doi":"10.1002/ctm2.215","title":"Retracted: Deceptology in cancer and vaccine sciences: Seeds of immune destruction‐mini electric shocks in mitochondria: Neuroplasticity‐electrobiology of response profiles and increased induced diseases in four generations – A hypothesis","year":2020,"lang":"en","type":"review","venue":"Clinical and Translational Medicine","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":4,"is_retracted":true,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Aging","funders":"","keywords":"Immune system; Medicine; Misinformation; Cancer; Disease; Immunology; Biology; Political science; Internal medicine","authors":[{"name":"Mahin Khatami","is_ca":true}],"retraction":{"nature":"Retraction","openalex_flagged":true},"screen_n_in":null,"score":{"opus":0.1294068086452716,"gpt":0.4219103323901751,"spread":0.2925035237449034,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009633849,0.0002618342,0.002095915,0.001078221,0.00003821529,0.000004152544,0.0001064061,0.0004233132,0.00001254182],"category_scores_gemma":[0.004707024,0.0001896502,0.00008682073,0.001591013,0.0006091471,0.00005074605,0.00002959004,0.0008419132,2.26132e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002627735,"about_ca_system_score_gemma":0.001448674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000304588,"about_ca_topic_score_gemma":0.00038631,"domain_scores_codex":[0.9964028,0.0008505366,0.00168359,0.0005645474,0.0002474736,0.0002510448],"domain_scores_gemma":[0.9920021,0.007404277,0.0002827165,0.0001201068,0.0001024929,0.00008829116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005619605,0.000443384,0.6798972,0.004387131,0.0001815536,0.0001295141,0.0001311473,5.318062e-7,0.0159065,0.0001684417,0.000007502586,0.2931275],"study_design_scores_gemma":[0.007252768,0.003384795,0.9780719,0.005430053,0.0007034943,0.0002426144,0.00002324437,0.0004089778,0.0002353846,0.0004683764,0.00354616,0.0002322182],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5819325,0.4164603,0.000008672841,0.0009048922,0.00004735306,0.0006051027,0.00003049529,0.000004762172,0.000005919315],"genre_scores_gemma":[0.4766235,0.5221224,0.0002474149,0.0006185,0.0001965426,0.0001460603,0.00002220627,0.00002179354,0.000001474562],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.2981747,"threshold_uncertainty_score":0.7733712,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4391886774","doi":"10.1002/ctm2.1593","title":"Wireless wearable devices for continuous monitoring of body sounds and motions","year":2024,"lang":"en","type":"article","venue":"Clinical and Translational Medicine","topic":"Context-Aware Activity Recognition Systems","field":"Computer Science","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Wearable computer; Wireless; Computer science; Wearable technology; Telecommunications; Embedded system","authors":[{"name":"Sun Hong Kim","is_ca":false},{"name":"Emily Jeanne","is_ca":true},{"name":"Wissam Shalish","is_ca":true},{"name":"Jaeyoung Yoo","is_ca":false},{"name":"John A. Rogers","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08537797304715085,"gpt":0.3761812984739767,"spread":0.2908033254268259,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006110104,0.0000709533,0.0002423792,0.00006300528,0.00006215249,0.00003470497,0.00008314,0.00005472947,0.000006225423],"category_scores_gemma":[0.00007178324,0.00005497559,0.00004657928,0.0001243327,0.0001753629,0.0002354969,0.00001452787,0.00009437777,0.000001471962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001654889,"about_ca_system_score_gemma":0.00003772572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001624541,"about_ca_topic_score_gemma":0.000006564935,"domain_scores_codex":[0.9990858,0.00004244908,0.0003939767,0.000244705,0.0001477991,0.00008529888],"domain_scores_gemma":[0.9978822,0.001812435,0.0000463894,0.00008166151,0.0001008179,0.00007648655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00002738328,0.0001011361,0.1868865,0.0005137924,0.0001730184,0.000006038673,0.0009053626,0.000002141961,0.0007663544,0.03520599,0.0001635376,0.7752488],"study_design_scores_gemma":[0.004083807,0.00103074,0.836165,0.003356424,0.0002075707,0.0001015754,0.0003964478,0.07851468,0.0002321649,0.05748936,0.01805045,0.0003718241],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4383262,0.007619522,0.5410493,0.0106588,0.001375265,0.0003299278,0.00002363628,0.0000992252,0.0005180854],"genre_scores_gemma":[0.9975759,0.0001555822,0.001664623,0.000041723,0.0004087228,0.0000169836,0.000003321476,0.000004523896,0.0001286408],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.774877,"threshold_uncertainty_score":0.224184,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4280596950","doi":"10.1002/ctm2.860","title":"Frequent exacerbators in severe asthma: Focus on clinical and transcriptional factors","year":2022,"lang":"en","type":"letter","venue":"Clinical and Translational Medicine","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Medicine; Asthma; Intensive care medicine; Disease; Pulmonology; Pediatrics; Internal medicine","authors":[{"name":"Neil C. Thomson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08164669605298798,"gpt":0.3634514822503624,"spread":0.2818047861973744,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009270398,0.0005019981,0.001433691,0.0003030668,0.000144715,0.00001097192,0.0001237325,0.0009452493,0.002662808],"category_scores_gemma":[0.0003430998,0.0003524538,0.0004027426,0.000200901,0.001534071,0.000064484,0.00002584977,0.003786708,0.000009685095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002149274,"about_ca_system_score_gemma":0.0003408334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004013931,"about_ca_topic_score_gemma":0.00001935229,"domain_scores_codex":[0.9952396,0.0005281185,0.001816742,0.001008845,0.001039619,0.0003670923],"domain_scores_gemma":[0.9968023,0.002172549,0.0002082561,0.0002733156,0.00007248542,0.0004710524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001684713,0.0007292697,0.7915676,0.0003865674,0.0003436632,0.001304446,0.0002267523,0.00000444526,0.000002744618,0.001283727,0.1662758,0.0361903],"study_design_scores_gemma":[0.005453857,0.002396293,0.5305733,0.0003687278,0.000209283,0.0000579,0.00005346206,0.000017013,1.862403e-7,0.001840815,0.4587839,0.0002452866],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2191987,0.008175268,0.00003333285,0.7673486,0.001595903,0.0009586097,0.0005143501,0.00006991673,0.002105338],"genre_scores_gemma":[0.5799962,0.002092343,0.0001064256,0.4043167,0.009915869,0.00006667693,0.002184134,0.0001069215,0.0012148],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.363032,"threshold_uncertainty_score":0.9998928,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}