{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":37,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":37,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"4468135ef0ab","filters":{"venue":"Current Cancer Drug Targets"}},"results":[{"id":"W2032167680","doi":"10.2174/15680096113139990076","title":"P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives","year":2013,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":392,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"P-glycoprotein; Multiple drug resistance; Efflux; Pharmacology; Drug resistance; Cancer cell; Chemotherapy; Drug; Cancer; Medicine; Cancer research; Biology; Internal medicine; Biochemistry","authors":[{"name":"Ziyad Binkhathlan","is_ca":true},{"name":"Afsaneh Lavasanifar","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04291776460267629,"gpt":0.3592649070629227,"spread":0.3163471424602464,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005980506,0.0008016084,0.001560149,0.00204861,0.0002783389,0.001025861,0.0008562343,0.001092742,0.004204058],"category_scores_gemma":[0.0005113193,0.0002455122,0.0005752411,0.002467414,0.0005145302,0.001514488,0.0006065273,0.002005922,0.002163163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005495132,"about_ca_system_score_gemma":0.0008917417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007159564,"about_ca_topic_score_gemma":0.001583178,"domain_scores_codex":[0.999827,0.00003268418,0.00002500122,0.00003101998,0.00006625705,0.00001811847],"domain_scores_gemma":[0.9996868,0.0001343046,0.00004547054,0.000009355024,0.00009140473,0.00003253856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007623032,0.0001469828,0.0001425034,0.01351819,0.00006619823,0.0002408735,0.0000509475,0.0003254754,0.002695339,0.002522996,0.01830044,0.9619138],"study_design_scores_gemma":[0.00003638094,0.000281436,0.001007459,0.003424044,0.0001882099,0.002058005,0.00007481689,0.0002208023,0.0008819364,0.001993448,0.9898009,0.00003264981],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001378002,0.9986766,0.0001266367,0.0002570177,0.00010745,0.000004530541,0.00001048106,0.000008044937,0.0006714388],"genre_scores_gemma":[0.0005004971,0.9988625,0.0001642402,0.00011955,0.00009742656,0.000004866508,0.00001471373,0.00000100381,0.0002352395],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004204058,"threshold_uncertainty_score":0.01406401,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2010349266","doi":"10.2174/156800907780058862","title":"From ONYX-015 to Armed Vaccinia Viruses: The Education and Evolution of Oncolytic Virus Development","year":2007,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Vaccinia; Oncolytic virus; Virology; Virus; Biology; Medicine; Genetics","authors":[{"name":"Anne Crompton","is_ca":true},{"name":"David H. Kirn","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05896900290161484,"gpt":0.4196466402453708,"spread":0.360677637343756,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002994144,0.0003660161,0.0002396327,0.0004307578,0.0003504967,0.001418896,0.0004427451,0.0008334301,0.001632124],"category_scores_gemma":[0.001630592,0.0002501302,0.0002109227,0.0003420204,0.001701753,0.002338514,0.001412261,0.002764463,0.0004519827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001976553,"about_ca_system_score_gemma":0.001465511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00127012,"about_ca_topic_score_gemma":0.001309989,"domain_scores_codex":[0.9995459,0.0001717458,0.00002949665,0.00008054925,0.000107107,0.00006518463],"domain_scores_gemma":[0.9994142,0.0002063219,0.00007540441,0.00004802719,0.0001010265,0.0001549694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004435142,0.0003208328,0.002186236,0.001229457,0.00003862245,0.0003217422,0.001983686,0.002859939,0.07552331,0.220359,0.01489258,0.6798412],"study_design_scores_gemma":[0.0001187761,0.0009421879,0.001915956,0.000803645,0.00003773154,0.0006463797,0.0005946372,0.002544911,0.0880686,0.04450572,0.8597587,0.00006277177],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1958529,0.5259261,0.1187364,0.0767032,0.005283622,0.0002275895,0.000244724,0.0005490793,0.07647642],"genre_scores_gemma":[0.5145271,0.3451857,0.08864762,0.01088918,0.001558423,0.0001259126,0.0003008519,0.0002514327,0.03851369],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002994144,"threshold_uncertainty_score":0.01583475,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1984087096","doi":"10.2174/156800907780058853","title":"Phase 1 Clinical Experience Using Intravenous Administration of PV701, an Oncolytic Newcastle Disease Virus","year":2007,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Georgetown University; University of Pennsylvania","keywords":"Oncolytic virus; Medicine; Tolerability; Adverse effect; Desensitization (medicine); Regimen; Dosing; Toxicity; Pharmacology; Bolus (digestion); Phases of clinical research; Newcastle disease; Clinical trial; Internal medicine; Oncology; Virus; Cancer; Immunology; Receptor","authors":[{"name":"Robert M. Lorence","is_ca":false},{"name":"M. Scot Roberts","is_ca":false},{"name":"James P. O’Neil","is_ca":false},{"name":"William S. Groene","is_ca":false},{"name":"Jeffrey S. Miller","is_ca":false},{"name":"Stephen N. Mueller","is_ca":false},{"name":"Michael K. Bamat","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2442977759870614,"gpt":0.5522660217318367,"spread":0.3079682457447753,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002376453,0.001413909,0.001363612,0.0001866659,0.0006425933,0.0007723552,0.0007207061,0.0009764624,0.001944913],"category_scores_gemma":[0.001716893,0.0004022384,0.000674616,0.0002617722,0.0007415144,0.0006317385,0.000340314,0.002357771,0.000661345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001131849,"about_ca_system_score_gemma":0.001430021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002913494,"about_ca_topic_score_gemma":0.003839732,"domain_scores_codex":[0.9992374,0.0003800282,0.0000285261,0.0001291113,0.0001038545,0.0001210953],"domain_scores_gemma":[0.999008,0.0002944014,0.000136691,0.0001161135,0.0001435132,0.0003013278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1024743,0.117827,0.0253814,0.001170302,0.001316062,0.001401631,0.002255746,0.009193517,0.1872611,0.0008832457,0.02925391,0.5215817],"study_design_scores_gemma":[0.06848326,0.8359825,0.03993313,0.00008267189,0.0004229671,0.001624448,0.0001625586,0.002341519,0.02444832,0.0004137687,0.02604183,0.00006308496],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9768684,0.005363663,0.004033223,0.001071944,0.0001752278,0.003236281,0.001496718,0.0001776184,0.007576932],"genre_scores_gemma":[0.9809783,0.003926911,0.003730362,0.00131902,0.0001859474,0.001614884,0.004381772,0.00005903224,0.003803897],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002913494,"threshold_uncertainty_score":0.01256806,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1996963479","doi":"10.2174/156800912799277511","title":"The Blood-Brain Barrier: Its Influence in the Treatment of Brain Tumors Metastases","year":2012,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"Canada Research Chairs","keywords":"Medicine; Blood–brain barrier; Chemotherapy; Brain tumor; Brain metastasis; Radiation therapy; Oncology; Brain cancer; Cancer; Internal medicine; Pathology; Central nervous system; Metastasis","authors":[{"name":"David Fortin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05824059173052305,"gpt":0.3778907565616442,"spread":0.3196501648311212,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006030891,0.0003908467,0.0006141704,0.001003288,0.0002779652,0.001308046,0.0004091212,0.001038125,0.00133917],"category_scores_gemma":[0.0009890844,0.0001051063,0.0003688652,0.0007578766,0.0008279332,0.001507253,0.0005667131,0.002037053,0.0006425618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001043668,"about_ca_system_score_gemma":0.001033943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001153734,"about_ca_topic_score_gemma":0.001355311,"domain_scores_codex":[0.9996527,0.0001020512,0.0000444943,0.00005666807,0.0001090524,0.00003505541],"domain_scores_gemma":[0.9993557,0.0003073187,0.0001064707,0.000008463301,0.0001847121,0.00003732706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000204575,0.00008519558,0.001288165,0.01755728,0.000128694,0.001211329,0.0003219464,0.0008232973,0.01140663,0.01869586,0.03622335,0.9120536],"study_design_scores_gemma":[0.00001457519,0.0004613974,0.004228069,0.004245636,0.0002046506,0.008157938,0.0003062264,0.0004584958,0.005856086,0.006830526,0.9691804,0.00005606383],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00057199,0.9957963,0.0003726452,0.001764163,0.0003506035,0.000003861382,0.000008790263,0.000008029258,0.001123576],"genre_scores_gemma":[0.005988468,0.9915609,0.0003709036,0.0007037601,0.0007059165,0.000006720617,0.00001131861,0.000003575521,0.0006483933],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00133917,"threshold_uncertainty_score":0.007572353,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071527358","doi":"10.2174/156800906777441753","title":"Regulation of Multidrug Resistance by Pro-Inflammatory Cytokines","year":2006,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Multiple drug resistance; Inflammation; Proinflammatory cytokine; P-glycoprotein; Biology; Drug resistance; ATP-binding cassette transporter; Efflux; Cancer; Mechanism (biology); Cancer research; Immunology; Pharmacology; Transporter; Gene","authors":[{"name":"Emmanuel A. Ho","is_ca":false},{"name":"Micheline Piquette‐Miller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02796013929946068,"gpt":0.3285002009923362,"spread":0.3005400616928756,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002850778,0.0006192508,0.0009005119,0.001046837,0.0002239318,0.0006918115,0.0004424534,0.000677943,0.002142238],"category_scores_gemma":[0.0002625193,0.0001562387,0.0002384983,0.0009964164,0.0003141713,0.0006787243,0.0003018752,0.0009017195,0.001815439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004130099,"about_ca_system_score_gemma":0.0005045751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003579151,"about_ca_topic_score_gemma":0.0006516923,"domain_scores_codex":[0.9998651,0.00002786706,0.00001667945,0.00002212646,0.00005518725,0.00001301949],"domain_scores_gemma":[0.9998534,0.00005154038,0.00002686678,0.000005459921,0.0000459763,0.00001672931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001371199,0.0001099106,0.0004579184,0.01064868,0.00006303164,0.0007376289,0.0001283471,0.0003620214,0.02032028,0.005887198,0.01574785,0.9454],"study_design_scores_gemma":[0.00004091102,0.0002062891,0.002332427,0.00133823,0.00006273349,0.003316789,0.0001075921,0.000134467,0.007294842,0.00281179,0.9823335,0.00002028923],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004112095,0.9972563,0.0002562208,0.000217038,0.0001584243,0.000006121175,0.00001059031,0.000009654843,0.0016745],"genre_scores_gemma":[0.002394207,0.995919,0.0002964193,0.0001416942,0.0001573446,0.00001002251,0.00001673244,0.000001154432,0.001063478],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002142238,"threshold_uncertainty_score":0.007166564,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2052792754","doi":"10.2174/1568009043332989","title":"Novel Approaches for Targeted Cancer Therapy","year":2004,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Jewish General Hospital; McGill University","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Cancer; Cancer therapy; Targeted therapy; Medicine; Internal medicine","authors":[{"name":"Veronique Guillemard","is_ca":true},{"name":"H. Uri Saragovi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1871171494037662,"gpt":0.4140247516751773,"spread":0.2269076022714111,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006521399,0.0008312711,0.0009357634,0.001268318,0.0003507712,0.001268309,0.001018669,0.001316987,0.007551503],"category_scores_gemma":[0.0003125881,0.0002703178,0.0005303692,0.000841924,0.0009201891,0.001506274,0.0008817145,0.002727668,0.004935428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001038302,"about_ca_system_score_gemma":0.000734337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004532414,"about_ca_topic_score_gemma":0.0007847426,"domain_scores_codex":[0.9997005,0.00006050792,0.00001551719,0.00004910344,0.0001426716,0.00003175095],"domain_scores_gemma":[0.9999141,0.0000286378,0.00001151047,0.000009277933,0.0000239901,0.00001250657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009262946,0.0002480773,0.0001722761,0.006290618,0.00009909592,0.0007634552,0.0002113282,0.001062628,0.02449115,0.0852081,0.0436574,0.8377032],"study_design_scores_gemma":[0.0000246647,0.00007988451,0.0001419152,0.000469562,0.00002103383,0.001093024,0.00003056875,0.0001854645,0.002726877,0.00891887,0.9862955,0.00001267479],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009507061,0.9566936,0.010775,0.002429272,0.001292804,0.00007780058,0.00005376748,0.00009694755,0.02763015],"genre_scores_gemma":[0.007981331,0.9648953,0.007427382,0.001942996,0.0007719051,0.0001575174,0.0001083319,0.00001565236,0.01669957],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007551503,"threshold_uncertainty_score":0.02526224,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2117191309","doi":"10.2174/156800911794519743","title":"Green Tea Polyphenols as Proteasome Inhibitors: Implication in Chemoprevention","year":2011,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Tea Polyphenols and Effects","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Cancer Institute; National Institutes of Health","keywords":"Proteasome; Prodrug; Pharmacology; Bioavailability; Chemistry; Cancer research; Cancer cell; Apoptosis; Proteasome inhibitor; Cancer; Biochemistry; Biology; Medicine; Internal medicine","authors":[{"name":"Huanjie Yang","is_ca":false},{"name":"Kristin R. Landis‐Piwowar","is_ca":false},{"name":"Tak Hang Chan","is_ca":true},{"name":"Q. Ping Dou","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05090194228805152,"gpt":0.3776791703544945,"spread":0.326777228066443,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003770898,0.0008686557,0.001277783,0.001938308,0.0002463707,0.000739208,0.0007226311,0.0009372722,0.002949843],"category_scores_gemma":[0.000295048,0.0002818209,0.000480796,0.002145926,0.0004302539,0.001083628,0.0004786818,0.001366322,0.001839546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000621328,"about_ca_system_score_gemma":0.0005650818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009632923,"about_ca_topic_score_gemma":0.002467204,"domain_scores_codex":[0.9998962,0.00001776157,0.00001302627,0.00001925666,0.0000375913,0.00001631065],"domain_scores_gemma":[0.999872,0.00004571246,0.0000224278,0.000005234523,0.00003632544,0.00001831443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001655717,0.0001845026,0.0002165605,0.01179109,0.0001033943,0.0003972617,0.00005889166,0.0006315776,0.006753601,0.002666223,0.01743532,0.9595962],"study_design_scores_gemma":[0.00005598295,0.0002107538,0.001469781,0.001890205,0.000140368,0.001460265,0.00006547742,0.0001877006,0.002435562,0.002201859,0.9898582,0.00002377978],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002520966,0.9987722,0.0001190053,0.0001546554,0.0000865274,0.000003690299,0.00001162172,0.000007845101,0.000592296],"genre_scores_gemma":[0.00120228,0.9978274,0.0001875866,0.00009736469,0.00007851681,0.000004959028,0.00001763434,0.00000133286,0.0005828273],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002949843,"threshold_uncertainty_score":0.009868205,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2032199025","doi":"10.2174/1568009023333926","title":"Mutant Epidermal Growth Factor Receptors as Targets for Cancer Therapy","year":2002,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Regional Cancer Foundation","funders":"","keywords":"Receptor; Epidermal growth factor receptor; Epidermal growth factor; Cancer research; Extracellular; Biology; Tyrosine kinase; Epitope; Cancer; Receptor tyrosine kinase; Cancer cell; Mutant; Growth factor receptor; Mutation; Growth factor receptor inhibitor; Antibody; Cell biology; Immunology; Biochemistry; Genetics; Gene","authors":[{"name":"Ian A.J. Lorimer","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1673419595737975,"gpt":0.4593383807002334,"spread":0.2919964211264359,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006299525,0.0007172528,0.001288973,0.002025222,0.0002791617,0.0008301669,0.0008853594,0.001191832,0.004005027],"category_scores_gemma":[0.0004026117,0.0002298917,0.0003931427,0.001745811,0.0004627461,0.001185672,0.0004508458,0.001669686,0.003575687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008157654,"about_ca_system_score_gemma":0.0005599665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006383507,"about_ca_topic_score_gemma":0.001320694,"domain_scores_codex":[0.9997746,0.0000457367,0.00001873007,0.00002828221,0.0001131863,0.00001940346],"domain_scores_gemma":[0.9998739,0.0000521041,0.00001533394,0.000005781581,0.0000365327,0.0000163583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001297799,0.0001691361,0.0001559286,0.006829886,0.0000686452,0.0004931891,0.00008326564,0.0005925024,0.005554898,0.008057117,0.04197028,0.9358953],"study_design_scores_gemma":[0.00003933404,0.0001018632,0.0003767978,0.0008640452,0.00003616896,0.001297172,0.0000318558,0.00009203702,0.0008212007,0.002024931,0.9943048,0.000009677078],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002581779,0.9961537,0.0002346601,0.0003415685,0.0002553672,0.000009021206,0.00001261967,0.0000126308,0.002722234],"genre_scores_gemma":[0.001191223,0.9955896,0.0003325839,0.0003452633,0.0001570369,0.00001245456,0.00002723101,0.000002314358,0.002342205],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004005027,"threshold_uncertainty_score":0.01339811,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988669425","doi":"10.2174/156800912802429337","title":"Targeting of Adhesion Molecules as a Therapeutic Strategy in Multiple Myeloma","year":2012,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"CD44; Integrin; Extracellular matrix; Cell biology; Cell adhesion molecule; Cell adhesion; Fibronectin; Chemistry; Laminin; Adhesion; Cancer research; Biology; Cell; Biochemistry","authors":[{"name":"Paola Neri","is_ca":true},{"name":"Nizar J. Bahlis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1171070461575847,"gpt":0.4100367581634505,"spread":0.2929297120058657,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002574062,0.0003509742,0.0005425256,0.0006348556,0.0001573725,0.0005158195,0.0003549109,0.0007379705,0.001205655],"category_scores_gemma":[0.0001289889,0.0001247258,0.0003153909,0.0004612246,0.0001608386,0.0004322137,0.000309233,0.001208089,0.0004738152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003892979,"about_ca_system_score_gemma":0.0002169479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003019054,"about_ca_topic_score_gemma":0.000742093,"domain_scores_codex":[0.9999207,0.00001804419,0.000006753607,0.000009285705,0.00003016616,0.00001503012],"domain_scores_gemma":[0.9999702,0.000008677742,0.000008371775,0.000001003446,0.000007087073,0.00000476687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000470489,0.0006098514,0.000518092,0.01215262,0.0002248375,0.00208177,0.0002250784,0.001824235,0.2138868,0.0124332,0.01849872,0.7370743],"study_design_scores_gemma":[0.0002455611,0.002605717,0.003389992,0.001900102,0.000349402,0.004846384,0.0001191715,0.001293596,0.04888801,0.004103564,0.9322085,0.00005014639],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007321391,0.9869322,0.001143126,0.0008579182,0.0003828536,0.00003578455,0.00003663386,0.00003863591,0.003251537],"genre_scores_gemma":[0.03540779,0.9590381,0.001688158,0.0008599839,0.0003574803,0.0000494164,0.00009098052,0.000006632714,0.002501529],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001205655,"threshold_uncertainty_score":0.004033327,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2061342795","doi":"10.2174/156800906777723976","title":"Radiation-Induced Bystander and other Non-Targeted Effects: Novel Intervention Points in Cancer Therapy?","year":2006,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"Canada Research Chairs; Irish Research Council; Science Foundation Ireland; Technological University Dublin; National Science Foundation","keywords":"Bystander effect; DNA damage; Radiation therapy; Cancer research; Cancer; Cancer cell; Medicine; Apoptosis; Biology; Immunology; DNA; Genetics; Internal medicine","authors":[{"name":"Carmel Mothersill","is_ca":true},{"name":"Colin Seymour","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04054962463183979,"gpt":0.3892558936366209,"spread":0.3487062690047811,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007640051,0.0006721548,0.002146882,0.0008099341,0.0003180235,0.001753857,0.001047223,0.002085107,0.00426214],"category_scores_gemma":[0.00045634,0.000313859,0.0007591,0.0008077672,0.001298824,0.003510084,0.0006207866,0.002572546,0.001890563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007219322,"about_ca_system_score_gemma":0.0007681531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003216315,"about_ca_topic_score_gemma":0.0006593789,"domain_scores_codex":[0.9997571,0.0000562336,0.00001803883,0.00006202862,0.00005778175,0.00004885398],"domain_scores_gemma":[0.9997633,0.00009798006,0.00003409414,0.00001202272,0.00006681704,0.00002576722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004558727,0.0003148393,0.0005184154,0.03076752,0.0001830578,0.001450804,0.0008228439,0.001353559,0.05514236,0.06528872,0.02448883,0.8192132],"study_design_scores_gemma":[0.0000614958,0.001077595,0.00158576,0.003758468,0.000150885,0.003394667,0.0006629704,0.0007180924,0.01026536,0.04076209,0.9374883,0.00007441746],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001405034,0.9911267,0.001751835,0.002648609,0.0008137377,0.00001694767,0.00002369622,0.00002691456,0.002186544],"genre_scores_gemma":[0.009846244,0.983793,0.001077997,0.001305064,0.001272099,0.00003367059,0.00003922886,0.000009506894,0.002623187],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00426214,"threshold_uncertainty_score":0.01425833,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071672251","doi":"10.2174/1568009043333005","title":"Targeting Translation for Treatment of Cancer - A Novel Role for IRES?","year":2004,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Children's Hospital of Eastern Ontario","funders":"","keywords":"Internal ribosome entry site; Translation (biology); Untranslated region; Biology; Eukaryotic translation; Cell biology; Protein biosynthesis; Cancer cell; Cancer; Cancer research; Messenger RNA; Genetics; Gene","authors":[{"name":"Martin Holčı́k","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07399969090101047,"gpt":0.3989401575790323,"spread":0.3249404666780218,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004761424,0.0008665534,0.001395682,0.001020851,0.000225435,0.0007802916,0.0007893577,0.001503672,0.002752389],"category_scores_gemma":[0.0002740959,0.0002497235,0.000414833,0.001049738,0.0006547637,0.001709457,0.0004317029,0.002443734,0.003537257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006301272,"about_ca_system_score_gemma":0.0004697897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004067789,"about_ca_topic_score_gemma":0.0008240431,"domain_scores_codex":[0.9998668,0.00002644465,0.00001492253,0.00002969931,0.00004623969,0.00001582017],"domain_scores_gemma":[0.9999064,0.00003649176,0.00001654571,0.000005718117,0.00002389334,0.00001097823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001448412,0.0001189547,0.0001412768,0.007227535,0.00008636373,0.0005095813,0.00008248827,0.0004000093,0.01480724,0.009796253,0.02892247,0.937763],"study_design_scores_gemma":[0.00006374592,0.0001757865,0.000524521,0.001016205,0.00005308089,0.00270273,0.00004176081,0.0001330372,0.002868002,0.003917028,0.9884828,0.00002143705],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002178221,0.9968591,0.00042003,0.0007146283,0.0003876227,0.000007170241,0.000009699522,0.00001367845,0.001370304],"genre_scores_gemma":[0.001716378,0.9945385,0.0006806265,0.0007313438,0.0003691625,0.00001370619,0.00002520998,0.00000457303,0.001920429],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002752389,"threshold_uncertainty_score":0.009207666,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2048425980","doi":"10.2174/1568009043481551","title":"Changes in the Apoptotic and Survival Signaling in Cancer Cells and Their Potential Therapeutic Implications","year":2004,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"CancerCare Manitoba; University of Manitoba","funders":"","keywords":"Signal transduction; Biology; Cancer research; Cancer cell; Apoptosis; Cell biology; Programmed cell death; Cancer; Kinase; Cell signaling; Genetics","authors":[{"name":"Albert F. Kaboré","is_ca":true},{"name":"James Johnston","is_ca":false},{"name":"Spencer B. Gibson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03671337346671952,"gpt":0.327231160591954,"spread":0.2905177871252345,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002394137,0.0003255882,0.0004916893,0.0006767432,0.000164563,0.0005472961,0.0003529209,0.0005985013,0.001779815],"category_scores_gemma":[0.000196739,0.0000941494,0.0002622071,0.0005928063,0.0002056206,0.0004985886,0.0002481004,0.0009937055,0.0005533237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004243125,"about_ca_system_score_gemma":0.0003247772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003027364,"about_ca_topic_score_gemma":0.0006654952,"domain_scores_codex":[0.9998993,0.00002177661,0.00001148484,0.00001605455,0.00003138874,0.00002013586],"domain_scores_gemma":[0.9999295,0.00002220912,0.00001329611,0.000002523986,0.00002411996,0.000008313134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002996093,0.000248075,0.0006402799,0.01054425,0.00007900964,0.0008295615,0.0001776637,0.0009112714,0.049354,0.01317032,0.01903814,0.9047079],"study_design_scores_gemma":[0.00005999303,0.0009032948,0.00385847,0.001562634,0.0001539631,0.005368796,0.0001945788,0.0005736672,0.02177927,0.007153941,0.9583414,0.00005003225],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00181697,0.9942735,0.0004671115,0.0005892647,0.0002473891,0.000008791446,0.00003643265,0.00001525429,0.002545308],"genre_scores_gemma":[0.01458228,0.9820101,0.0006652197,0.0004249107,0.0003518501,0.00002098036,0.00008074927,0.000003529867,0.001860398],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001779815,"threshold_uncertainty_score":0.005954087,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2100388782","doi":"10.2174/156800911793743600","title":"Human Equilibrative Nucleoside Transporter 1 (hENT1) Levels Predict Response to Gemcitabine in Patients With Biliary Tract Cancer (BTC)","year":2010,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta; Alberta Cancer Foundation","funders":"","keywords":"Gemcitabine; Medicine; Internal medicine; Oncology; Regimen; Univariate analysis; Biliary tract; Nucleoside transporter; Cancer; Gastroenterology; Multivariate analysis; Transporter","authors":[{"name":"Daniele Santini","is_ca":false},{"name":"Gaia Schiavon","is_ca":false},{"name":"Bruno Vincenzi","is_ca":false},{"name":"Carol E. Cass","is_ca":true},{"name":"Enrico Vasile","is_ca":false},{"name":"Andrea D. Manazza","is_ca":false},{"name":"V. Catalano","is_ca":false},{"name":"Giacomo Giulio Baldi","is_ca":false},{"name":"Rai‐Hua Lai","is_ca":true},{"name":"Stefania Rizzo","is_ca":false},{"name":"Alice Giacobino","is_ca":true},{"name":"Luigi Chiusa","is_ca":false},{"name":"Michele Caraglia","is_ca":false},{"name":"Antonio Russo","is_ca":false},{"name":"John R. Mackey","is_ca":true},{"name":"Alfredo Falcone","is_ca":false},{"name":"Giuseppe Tonini","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0264076660779159,"gpt":0.3325899278775272,"spread":0.3061822617996113,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002264858,0.0001538301,0.000235258,0.0002884147,0.0002118161,0.0003148663,0.0001100946,0.0002942709,0.0009534259],"category_scores_gemma":[0.0008511409,0.0001108224,0.0001623568,0.0003412625,0.000155223,0.0001977142,0.0001985017,0.0002805636,0.0001828704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002145166,"about_ca_system_score_gemma":0.0001438132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006438665,"about_ca_topic_score_gemma":0.0009629297,"domain_scores_codex":[0.9998916,0.00002947226,0.00001380052,0.00002432291,0.00001716964,0.00002355821],"domain_scores_gemma":[0.9995684,0.0001264309,0.0001682508,0.0000177918,0.00003929389,0.00007984947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003635654,0.00001131991,0.9969944,0.000007317969,0.00001540307,0.00007882361,0.0000159964,0.0000578912,0.001212559,0.000004834535,0.00004057732,0.001197311],"study_design_scores_gemma":[0.00001368634,0.0001680453,0.9974905,0.000003497514,0.00003737679,0.000892708,0.0000596627,0.000493023,0.000600154,0.00002410559,0.0002150484,0.000002133018],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9995158,0.0002374435,0.00004199736,0.0000200683,0.000001654898,0.000002295671,0.00005289891,0.000001342576,0.0001264829],"genre_scores_gemma":[0.9996938,0.0000678613,0.00005196105,0.000008722572,0.000003219071,0.000002519154,0.0001089764,8.08033e-7,0.00006218888],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0009534259,"threshold_uncertainty_score":0.003189564,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2327659954","doi":"10.2174/156800911794519770","title":"Clioquinol – A Novel Copper-Dependent and Independent Proteasome Inhibitor","year":2011,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Biological Research and Disease Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research; Princess Margaret Cancer Centre","funders":"","keywords":"Clioquinol; Proteasome inhibitor; Proteasome; Pharmacology; Chemistry; Extracellular; Intracellular; Mechanism of action; Prodrug; Cancer research; Biochemistry; Medicine; In vitro","authors":[{"name":"Aaron D. Schimmer","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07753226772495421,"gpt":0.3724427619954073,"spread":0.2949104942704531,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001626996,0.0004988211,0.0006023102,0.001062689,0.0001682116,0.0003301933,0.0005889387,0.0004773283,0.001223187],"category_scores_gemma":[0.0001218922,0.0001852132,0.0002569254,0.0006795012,0.0002217937,0.0004932745,0.0002395224,0.0009081444,0.00113596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004704471,"about_ca_system_score_gemma":0.0003142977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006654758,"about_ca_topic_score_gemma":0.001705692,"domain_scores_codex":[0.9999214,0.000009380496,0.000008201063,0.00001655744,0.00003327692,0.00001108438],"domain_scores_gemma":[0.999966,0.000008015661,0.000007287998,0.000001406113,0.00001255814,0.0000047987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001306069,0.000185182,0.000161313,0.00810717,0.00008025684,0.0005525096,0.00005386736,0.0007462398,0.0507702,0.00450972,0.02327493,0.9114281],"study_design_scores_gemma":[0.00005534733,0.0002744174,0.0008278172,0.0005037234,0.00005358936,0.00268326,0.00002191896,0.0002531357,0.01374286,0.0009901932,0.9805701,0.00002349081],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001384833,0.9941478,0.0008850531,0.0002306778,0.0001901504,0.00001760133,0.00003396811,0.00003785541,0.003072042],"genre_scores_gemma":[0.01017996,0.9836061,0.001112223,0.0003334908,0.0001483969,0.0000285987,0.0001339413,0.000005125694,0.004452074],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001223187,"threshold_uncertainty_score":0.004091918,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011022421","doi":"10.2174/156800905774574020","title":"Cellular and Molecular Surrogate Markers to Monitor Targeted and Non- Targeted Antiangiogenic Drug Activity and Determine Optimal Biologic Dose","year":2005,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"National Cancer Institute","keywords":"Medicine; Pharmacology; Drug; Cancer; Drug development; Dosing; Pharmacokinetics; Pharmacodynamics; Cancer research; Internal medicine","authors":[{"name":"Yuval Shaked","is_ca":true},{"name":"Guido Bocci","is_ca":true},{"name":"Raquel Muñoz","is_ca":true},{"name":"Shan Man","is_ca":true},{"name":"John M.L. Ebos","is_ca":true},{"name":"Daniel J. Hicklin","is_ca":false},{"name":"Francesco Bertolini","is_ca":false},{"name":"Robert J. D’Amato","is_ca":false},{"name":"Robert S. Kerbel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01916500562821551,"gpt":0.3107667388099772,"spread":0.2916017331817617,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00214213,0.0008072824,0.0007531031,0.001417553,0.0002525573,0.001317614,0.0004525423,0.001067995,0.002162713],"category_scores_gemma":[0.00151472,0.0002869285,0.0004697481,0.0009893803,0.0005710818,0.0009067609,0.0004229278,0.001738178,0.0009314013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006153088,"about_ca_system_score_gemma":0.0004627429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002758182,"about_ca_topic_score_gemma":0.0005427248,"domain_scores_codex":[0.9971823,0.00125354,0.0002560586,0.0002371753,0.0009421239,0.00012889],"domain_scores_gemma":[0.9984181,0.0004338082,0.0005051031,0.0001981736,0.0003297921,0.0001149507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005278162,0.0003445334,0.004464423,0.0007730906,0.00006723543,0.00009639374,0.00007249944,0.003051818,0.9339846,0.00441388,0.00102196,0.05118169],"study_design_scores_gemma":[0.00004442472,0.002170268,0.007423691,0.0001117755,0.00008220251,0.0005134062,0.00009875314,0.007980672,0.9553118,0.001664893,0.02454819,0.00004993695],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.2890428,0.0928246,0.5797243,0.001935201,0.001239285,0.001245947,0.004806937,0.001578694,0.02760226],"genre_scores_gemma":[0.6923618,0.01870118,0.2721471,0.001039026,0.0003963385,0.001470158,0.003139141,0.0002010843,0.0105441],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002162713,"threshold_uncertainty_score":0.01132882,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2111967651","doi":"10.2174/156800905774574011","title":"Hypomethylation of Urokinase (uPA) Promoter in Breast and Prostate Cancer: Prognostic and Therapeutic Implications","year":2005,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Cancer research; Biology; DNA methylation; Prostate cancer; Epigenetics; Gene silencing; Cancer; Urokinase receptor; Metastasis; Breast cancer; Tumor progression; Gene; Plasminogen activator; Gene expression; Endocrinology; Genetics","authors":[{"name":"Pouya Pakneshan","is_ca":true},{"name":"Moshe Szyf","is_ca":false},{"name":"Shafaat A. Rabbani","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03075453478558431,"gpt":0.3526805359875418,"spread":0.3219260012019575,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003967544,0.0004457843,0.000923635,0.0008566488,0.0001544159,0.0003955622,0.0005282243,0.0006968832,0.001519513],"category_scores_gemma":[0.0004042107,0.0001493504,0.0002100817,0.001310739,0.0002555029,0.0004358142,0.0002209748,0.0007497261,0.001327534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004881469,"about_ca_system_score_gemma":0.0004273185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009460796,"about_ca_topic_score_gemma":0.001681389,"domain_scores_codex":[0.9998844,0.0000250584,0.00001276957,0.0000287122,0.00004008432,0.000009074139],"domain_scores_gemma":[0.9998646,0.00005772308,0.00002130085,0.000004455475,0.00004134952,0.00001053604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007995601,0.00002684115,0.0007741363,0.003920166,0.00006784109,0.0004885407,0.00004435291,0.0003698295,0.004520161,0.001183795,0.01476009,0.9737642],"study_design_scores_gemma":[0.00003690143,0.0002203196,0.008823183,0.001757033,0.0002684855,0.01261022,0.0001303071,0.0003792924,0.004518908,0.002728662,0.9684912,0.00003547676],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004173569,0.9979353,0.0003048749,0.0003395925,0.0001007297,0.000002767393,0.00001907794,0.00001044259,0.0008699245],"genre_scores_gemma":[0.003295062,0.9947498,0.0004840234,0.0002104134,0.0001740761,0.000006160513,0.00003590178,0.000002188152,0.001042314],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001519513,"threshold_uncertainty_score":0.005083263,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2164239756","doi":"10.2174/156800912802429292","title":"Mouse Models as a Translational Platform for the Development of New Therapeutic Agents in Multiple Myeloma","year":2012,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Associazione Italiana per la Ricerca sul Cancro","keywords":"Stromal cell; Multiple myeloma; Syngenic; In vivo; Cancer research; Bone marrow; Tumor microenvironment; Medicine; Biology; Immunology; Tumor cells","authors":[{"name":"Pierfrancesco Tassone","is_ca":false},{"name":"Paola Neri","is_ca":true},{"name":"Renate Burger","is_ca":false},{"name":"Maria Teresa Di Martino","is_ca":false},{"name":"Emanuela Leone","is_ca":false},{"name":"Nicola Amodio","is_ca":false},{"name":"Michele Caraglia","is_ca":false},{"name":"Pierosandro Tagliaferri","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3272550846793235,"gpt":0.4419032954217033,"spread":0.1146482107423798,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000909965,0.0007722696,0.001230065,0.002021941,0.0001684575,0.0007908481,0.0008158673,0.001024779,0.00206702],"category_scores_gemma":[0.0003467858,0.0002967188,0.0004619877,0.00130982,0.0006783702,0.001053189,0.0004769205,0.00232631,0.001407843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005216701,"about_ca_system_score_gemma":0.000568825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004804239,"about_ca_topic_score_gemma":0.0007966495,"domain_scores_codex":[0.9997577,0.00006000184,0.00003245719,0.00003275489,0.00009974357,0.00001734795],"domain_scores_gemma":[0.9997122,0.0001369628,0.00005283473,0.00001651049,0.00005810595,0.00002337851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001818095,0.0003124129,0.000236725,0.01454614,0.00009030753,0.0004172028,0.00008056683,0.0005784297,0.0528964,0.01277282,0.01726282,0.9006243],"study_design_scores_gemma":[0.00004530621,0.0004346558,0.001002761,0.001613226,0.0001311703,0.00199844,0.00004841198,0.0001808053,0.01072879,0.002440428,0.9813461,0.00002984376],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006429368,0.9946703,0.001462033,0.0003105537,0.0001945231,0.00002892803,0.00005340297,0.00003371837,0.002603606],"genre_scores_gemma":[0.002455342,0.9943427,0.001712508,0.000246258,0.0001201975,0.00004018089,0.00008830693,0.0000054762,0.000989059],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00206702,"threshold_uncertainty_score":0.006914914,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2003470917","doi":"10.2174/156800908786733450","title":"Anti-Angiogenic Targets in the Treatment of Advanced Renal Cell Carcinoma","year":2008,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; Health Canada; Memorial Sloan-Kettering Cancer Center","keywords":"Pazopanib; Temsirolimus; Sunitinib; Axitinib; Sorafenib; Everolimus; Medicine; Vascular endothelial growth factor; Cancer research; Renal cell carcinoma; Bevacizumab; Platelet-derived growth factor receptor; Angiogenesis; PI3K/AKT/mTOR pathway; Tyrosine-kinase inhibitor; Growth factor; Pharmacology; Internal medicine; Cancer; Biology; Signal transduction; VEGF receptors; Discovery and development of mTOR inhibitors; Receptor; Chemotherapy; Hepatocellular carcinoma","authors":[{"name":"Daniel Yick Chin Heng","is_ca":false},{"name":"Ronald M. Bukowski","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05341450169617008,"gpt":0.340254233950875,"spread":0.2868397322547049,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003925925,0.0005717599,0.001047787,0.001925204,0.0002362193,0.0005714142,0.000572342,0.000659488,0.003108765],"category_scores_gemma":[0.0002769497,0.0001949486,0.0003164164,0.001860165,0.0002683664,0.0007226001,0.0003203685,0.001186891,0.002600553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004855912,"about_ca_system_score_gemma":0.0005881924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009691391,"about_ca_topic_score_gemma":0.002456921,"domain_scores_codex":[0.9998734,0.00002066699,0.00001283828,0.00001572416,0.00006500209,0.00001236086],"domain_scores_gemma":[0.9998934,0.0000354923,0.00001993271,0.000003002177,0.00003327028,0.00001489216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009081895,0.0001531072,0.0001699967,0.006175895,0.00006756833,0.0003299844,0.00004535211,0.0003779928,0.003286691,0.001749289,0.02132307,0.9662302],"study_design_scores_gemma":[0.00005531414,0.000204083,0.001441316,0.001422168,0.00008015224,0.001890573,0.00004483827,0.0001313932,0.000971281,0.001027341,0.9927185,0.00001313584],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003516459,0.9967655,0.0001545567,0.0002032329,0.0001522721,0.00001008844,0.00001571772,0.00001103469,0.002336019],"genre_scores_gemma":[0.001242118,0.9967759,0.0002928189,0.0002000744,0.0001270703,0.000009375524,0.00003381076,0.000001512208,0.001317213],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003108765,"threshold_uncertainty_score":0.01039988,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2149276366","doi":"10.2174/156800906778194586","title":"Development and Assessment of Conventional and Targeted Drug Combinations for Use in the Treatment of Aggressive Breast Cancers","year":2006,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Drug; Medicine; Intensive care medicine; Drug development; Pharmacology; Oncology","authors":[{"name":"Dawn Waterhouse","is_ca":true},{"name":"K. Gelmon","is_ca":false},{"name":"Richard Klasa","is_ca":false},{"name":"K.-H. Chi","is_ca":false},{"name":"D. Huntsman","is_ca":false},{"name":"Euan Ramsay","is_ca":false},{"name":"Ellen K. Wasan","is_ca":false},{"name":"Lincoln Edwards","is_ca":true},{"name":"Christopher Tucker","is_ca":false},{"name":"Jason Zastre","is_ca":false},{"name":"Yi Zhang","is_ca":true},{"name":"Donald T. Yapp","is_ca":false},{"name":"Wieslawa H. Dragowska","is_ca":false},{"name":"S. Dedha","is_ca":false},{"name":"Marcel B. Bally","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05245195177791379,"gpt":0.3971150038702496,"spread":0.3446630520923358,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007270963,0.0008713055,0.001318691,0.002281496,0.0002264663,0.001008559,0.0009689235,0.0009889845,0.00217067],"category_scores_gemma":[0.000602618,0.0004063665,0.0005381884,0.001712662,0.000528487,0.001242711,0.0005203843,0.001624684,0.001448854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006256194,"about_ca_system_score_gemma":0.0008989649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000713146,"about_ca_topic_score_gemma":0.00133203,"domain_scores_codex":[0.9997641,0.0000404019,0.00003001343,0.000038637,0.0001036973,0.00002304324],"domain_scores_gemma":[0.9997684,0.00009887823,0.0000436938,0.00000811323,0.00006283453,0.000018066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009094911,0.0001443368,0.00015699,0.01595839,0.00008839824,0.0002494208,0.00006208487,0.0009597474,0.007084557,0.00591367,0.01214844,0.957143],"study_design_scores_gemma":[0.00003408263,0.0002789823,0.0006541063,0.001893757,0.00009813985,0.001148526,0.00004326165,0.0002231288,0.002682268,0.001753961,0.9911667,0.00002317507],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004099397,0.9969178,0.0005272409,0.0001932907,0.000162645,0.00002361271,0.00002893255,0.00001615735,0.00172032],"genre_scores_gemma":[0.001450644,0.9970464,0.0005907886,0.0001511593,0.00008188286,0.00002256308,0.00003542369,0.000002541212,0.000618654],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002281496,"threshold_uncertainty_score":0.007261634,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2121862563","doi":"10.2174/1568009615666150105115047","title":"Nano-pharmaceutical Formulations for Targeted Drug Delivery against HER2 in Breast Cancer","year":2015,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Saskatchewan Health Authority","funders":"","keywords":"Drug delivery; Breast cancer; Monoclonal antibody; Nanotechnology; Targeted drug delivery; Nanomedicine; Drug; Cancer; Dendrimer; Liposome; Cancer therapy; Flexibility (engineering); Medicine; Pharmacology; Nanoparticle; Chemistry; Materials science; Antibody; Immunology; Internal medicine","authors":[{"name":"Sams M. A. Sadat","is_ca":false},{"name":"Soodabeh Saeidnia","is_ca":false},{"name":"Adil J. Nazarali","is_ca":false},{"name":"Azita Haddadi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06493306173260915,"gpt":0.3781428014225207,"spread":0.3132097396899116,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003605295,0.0007021858,0.0008138403,0.002253461,0.0002594859,0.0004737746,0.0004649859,0.0008004496,0.002407362],"category_scores_gemma":[0.0002102133,0.0002881327,0.0004718376,0.0012094,0.0002821029,0.0007465873,0.0005088125,0.001168776,0.001808067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004395663,"about_ca_system_score_gemma":0.0004231002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005433115,"about_ca_topic_score_gemma":0.001102282,"domain_scores_codex":[0.9998671,0.0000192532,0.00001201456,0.00002023769,0.00006540056,0.00001597797],"domain_scores_gemma":[0.9999416,0.00001974304,0.00001544517,0.000002585814,0.00001456835,0.000005986074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006347738,0.0002248064,0.0001467524,0.01647111,0.00008422822,0.0004131965,0.00009654962,0.0007581104,0.04364568,0.008346439,0.01430212,0.9154475],"study_design_scores_gemma":[0.00003116029,0.0002749148,0.0008989947,0.001936533,0.00009016546,0.00218921,0.0000512762,0.0004169925,0.01394374,0.001945995,0.978193,0.00002793049],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001041538,0.9952756,0.0008297776,0.0001282393,0.0001362473,0.00002725424,0.0000263301,0.00001654052,0.002518498],"genre_scores_gemma":[0.00554071,0.9902487,0.001316935,0.0001651753,0.00008455936,0.00003603959,0.00005198454,0.000004843069,0.002551044],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002407362,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2112773270","doi":"10.2174/156800912801784857","title":"Inhibition of Protein N-Myristoylation: A Therapeutic Protocol in Developing Anticancer Agents","year":2012,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Myristoylation; Biology; Kinase; Cancer; Cancer research; Carcinogenesis; Cancer cell; Pharmacology; Biochemistry; Phosphorylation","authors":[{"name":"Umashankar Das","is_ca":true},{"name":"Sujeet Kumar","is_ca":true},{"name":"Jonathan R. Dimmock","is_ca":false},{"name":"Rajendra K. Sharma","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08981349512724712,"gpt":0.418618193008455,"spread":0.3288046978812079,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002337615,0.0004388374,0.0003662706,0.0005753469,0.00020438,0.0003096434,0.0004071192,0.0006509068,0.001386727],"category_scores_gemma":[0.00009982412,0.0002090867,0.0003244105,0.0004286839,0.0003171884,0.0007308056,0.0003745893,0.001250394,0.0008547552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004547676,"about_ca_system_score_gemma":0.0003044867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002830709,"about_ca_topic_score_gemma":0.0006052713,"domain_scores_codex":[0.9999048,0.00001759181,0.000008881872,0.00002441689,0.00003016363,0.00001410292],"domain_scores_gemma":[0.9999679,0.000007095186,0.000007669033,0.000003054082,0.000009329176,0.000004979572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001879747,0.0001899891,0.0001807347,0.003958955,0.00004387881,0.0004452092,0.0000969608,0.001090979,0.8076771,0.0112193,0.003227334,0.1716815],"study_design_scores_gemma":[0.00005869785,0.001239945,0.001137254,0.0003237196,0.00008693896,0.001901519,0.00004479179,0.001033854,0.5293572,0.002006065,0.4627726,0.0000373427],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06789652,0.8373924,0.05776074,0.003210382,0.00118799,0.0004527871,0.0003914318,0.0003436105,0.03136413],"genre_scores_gemma":[0.2384027,0.7085792,0.02803046,0.001888115,0.0004321729,0.0004241471,0.0005356264,0.00004640907,0.02166127],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001386727,"threshold_uncertainty_score":0.004639089,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2027556747","doi":"10.2174/156800910791859452","title":"Antisense Treatment in Human Prostate Cancer and Melanoma","year":2010,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Victoria Hospital; Western University","funders":"Canadian Institutes of Health Research; Francis Crick Institute","keywords":"Prostate cancer; Antisense therapy; Clusterin; Cancer; Cancer research; RNA; Medicine; Prostate; Biology; Internal medicine; Gene; Apoptosis; Locked nucleic acid; Genetics","authors":[{"name":"Christine Di Cresce","is_ca":true},{"name":"James Koropatnick","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05579727939079897,"gpt":0.4177648667764648,"spread":0.3619675873856658,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003586125,0.0008731696,0.001069778,0.001801323,0.0003294531,0.000648597,0.0005390101,0.000904492,0.00348356],"category_scores_gemma":[0.0002692896,0.0002719598,0.0003830894,0.001351293,0.0004175699,0.0007527288,0.0004893281,0.001369271,0.002984701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006045783,"about_ca_system_score_gemma":0.0006027484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001537703,"about_ca_topic_score_gemma":0.003560642,"domain_scores_codex":[0.9998634,0.0000246388,0.00001340681,0.00002690094,0.00005969078,0.00001197053],"domain_scores_gemma":[0.9999231,0.00002935392,0.00001379147,0.0000037623,0.00002065442,0.00000933822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000727861,0.000109093,0.0001300063,0.008761024,0.00005482255,0.0003629669,0.0000944021,0.0004320195,0.00869644,0.006113816,0.03466136,0.9405113],"study_design_scores_gemma":[0.00002069004,0.0001111913,0.0005443611,0.001135651,0.00003235268,0.001509996,0.00003181139,0.00005979381,0.001557999,0.001412192,0.9935702,0.00001363405],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001951447,0.99599,0.0002219677,0.0001476778,0.0002328368,0.0000116933,0.00001806795,0.0000115771,0.003171101],"genre_scores_gemma":[0.001473127,0.9946956,0.0003058229,0.000317623,0.0001428621,0.00001710895,0.0000449385,0.000003230906,0.002999727],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00348356,"threshold_uncertainty_score":0.01165366,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W131285836","doi":"10.2174/156800907780058844","title":"Oncolytic Viruses: Whats Next?","year":2007,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Oncolytic virus; Exploit; Cancer; Biology; Computational biology; Virus; Computer science; Virology; Computer security; Genetics","authors":[{"name":"John C. Bell","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1284561124885577,"gpt":0.4518016595399557,"spread":0.323345547051398,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001858933,0.001055673,0.001582942,0.001195286,0.0006369116,0.002352476,0.001088536,0.002928756,0.003797395],"category_scores_gemma":[0.001342065,0.0004584405,0.0004812333,0.001425712,0.001539854,0.008083687,0.0008560683,0.004910797,0.003931161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00133293,"about_ca_system_score_gemma":0.001544542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001384698,"about_ca_topic_score_gemma":0.00262354,"domain_scores_codex":[0.9996086,0.00009913395,0.00003593648,0.00005437576,0.000159573,0.00004238134],"domain_scores_gemma":[0.9993789,0.000267404,0.00005840949,0.0000270036,0.0001666358,0.0001016229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001106681,0.00009032226,0.0002759379,0.005106899,0.0000357652,0.0003167587,0.0001799057,0.0003628097,0.002423433,0.02421044,0.06495192,0.9019351],"study_design_scores_gemma":[0.00001652359,0.00008544489,0.0001999706,0.00142454,0.00002031919,0.000808522,0.0002097154,0.00009202451,0.0005406389,0.009622484,0.986961,0.00001882457],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001520848,0.9893049,0.0004814582,0.006259436,0.001816337,0.000009087608,0.00001407743,0.00001968637,0.001942877],"genre_scores_gemma":[0.001144909,0.9925114,0.0005895413,0.002464594,0.001349387,0.00001145726,0.0000145973,0.000005631217,0.001908431],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003797395,"threshold_uncertainty_score":0.01270354,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4206024180","doi":"10.2174/1568009622666211231140623","title":"The Potential of Natural Products in the Treatment of Triple-negative Breast Cancer","year":2021,"lang":"en","type":"article","venue":"Current Cancer Drug Targets","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Triple-negative breast cancer; Natural (archaeology); Breast cancer; Medicine; Cancer; Internal medicine; Biology","authors":[{"name":"Danny Yu Jia Ke","is_ca":true},{"name":"Sara El‐Sahli","is_ca":true},{"name":"Lisheng Wang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01021136430356674,"gpt":0.2927029449318295,"spread":0.2824915806282628,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002650657,0.0003239142,0.0004928036,0.001293539,0.000150408,0.0004840855,0.0002068163,0.0003799169,0.001771383],"category_scores_gemma":[0.0003216557,0.00008998756,0.0004516446,0.0006136096,0.0001500409,0.0004206877,0.0002784891,0.0007696335,0.000634046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001901397,"about_ca_system_score_gemma":0.0002587696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003070602,"about_ca_topic_score_gemma":0.0008111185,"domain_scores_codex":[0.9999088,0.00002359095,0.00001174074,0.00001374778,0.00003175496,0.00001043626],"domain_scores_gemma":[0.9998847,0.00003994112,0.00002643471,0.000004601605,0.00003235141,0.00001194105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006282895,0.0003768831,0.0007302702,0.0159561,0.0002323461,0.0009080225,0.0001049425,0.0005133998,0.04898937,0.00315081,0.00959025,0.9188194],"study_design_scores_gemma":[0.0001812488,0.002621656,0.009618263,0.004315886,0.0006806241,0.004503452,0.0002284306,0.0004479757,0.02809721,0.003572284,0.945663,0.00006991458],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00678396,0.9880504,0.000589487,0.0005453507,0.0002680231,0.00002610919,0.0001552788,0.00002418146,0.003557278],"genre_scores_gemma":[0.04664994,0.948112,0.001661443,0.0006701556,0.0002804066,0.00003061825,0.0003267408,0.000008779256,0.002259923],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001771383,"threshold_uncertainty_score":0.005925894,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2422973035","doi":"10.2174/1568009615666150616123548","title":"Chemotherapy Delivery Strategies to the Central Nervous System: neither Optional nor Superfluous","year":2015,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Drug delivery; Medicine; Blood–brain barrier; Glioblastoma; Chemotherapy; Radiation therapy; Brain tumor; Central nervous system; Surgery; Pathology; Internal medicine; Cancer research","authors":[{"name":"Annie Drapeau","is_ca":false},{"name":"David Fortin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05580880027447598,"gpt":0.3625731993795175,"spread":0.3067643991050415,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002469598,0.0006889097,0.001000057,0.0014408,0.0002620611,0.0007276564,0.0005789208,0.0007995562,0.002693505],"category_scores_gemma":[0.0003424694,0.0002392412,0.000424466,0.001188592,0.0004021123,0.001025289,0.0004495322,0.001243132,0.001547425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005508678,"about_ca_system_score_gemma":0.0006749073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001068471,"about_ca_topic_score_gemma":0.001856017,"domain_scores_codex":[0.9998697,0.00002068225,0.00001737002,0.00002866259,0.00004922556,0.00001424623],"domain_scores_gemma":[0.9998778,0.00005486223,0.00002250968,0.000005039113,0.00003104375,0.000008728122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006324449,0.00008206604,0.0001773932,0.0230559,0.00008214991,0.0003650702,0.0001221221,0.0004693274,0.01046502,0.006147826,0.01730393,0.9416658],"study_design_scores_gemma":[0.00001411234,0.0001412493,0.000709756,0.002313388,0.0001056366,0.002386095,0.00006071849,0.0001696731,0.003516928,0.00142637,0.9891377,0.000018305],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003803541,0.9968596,0.0003161629,0.000217318,0.0001459322,0.000007274031,0.00001430303,0.000009603443,0.002049424],"genre_scores_gemma":[0.00178664,0.9967608,0.0002684681,0.0001476677,0.00008357748,0.000007945045,0.00001982362,0.000002005853,0.0009230524],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002693505,"threshold_uncertainty_score":0.009010673,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2786620549","doi":"10.2174/1568009617666170206111609","title":"Oncolytic Viruses: The Best is Yet to Come","year":2018,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Oncolytic virus; Virotherapy; Tumor microenvironment; Medicine; Immune system; Immune modulation; Immunology","authors":[{"name":"Chantal G. Lemay","is_ca":true},{"name":"Brian A. Keller","is_ca":true},{"name":"Robert E. Edge","is_ca":true},{"name":"Masato Abei","is_ca":false},{"name":"John C. Bell","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09197668856040245,"gpt":0.4374924473297759,"spread":0.3455157587693735,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001571652,0.0007008273,0.001316358,0.000947281,0.0005579737,0.003261409,0.0008627578,0.00215397,0.00428799],"category_scores_gemma":[0.001897554,0.0003360164,0.0004616567,0.0009987364,0.001315645,0.006440073,0.00130723,0.003266122,0.002791791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006951718,"about_ca_system_score_gemma":0.001644057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006687004,"about_ca_topic_score_gemma":0.00139071,"domain_scores_codex":[0.9996169,0.00007461983,0.00004420249,0.00006945252,0.0001480706,0.0000467446],"domain_scores_gemma":[0.9988073,0.0006686896,0.00009251993,0.00005391059,0.0002524235,0.0001252102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009381741,0.00009259539,0.0002355068,0.009513637,0.00005396593,0.0002348608,0.0002187395,0.0003735618,0.005396333,0.02367636,0.03645669,0.9236539],"study_design_scores_gemma":[0.000007357447,0.00008731491,0.0001239018,0.001585151,0.00002966414,0.0006649857,0.0001318415,0.00008125111,0.001314526,0.006264536,0.9896909,0.00001865001],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003185218,0.9931468,0.0006994574,0.003389472,0.0008436104,0.000005930872,0.00002673829,0.00002706575,0.001542278],"genre_scores_gemma":[0.001908027,0.9941608,0.0007528414,0.001115249,0.0006216735,0.00000805912,0.00004375452,0.000007699819,0.001381879],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00428799,"threshold_uncertainty_score":0.01434475,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2107103889","doi":"10.2174/156800909789760393","title":"Challenging the Current Approaches to Multiple Myeloma-Related Bone Disease: From Bisphosphonates to Target Therapy","year":2009,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Comprehensive Cancer Network","keywords":"Multiple myeloma; Medicine; Bone disease; Disease; Current (fluid); Intensive care medicine; Bioinformatics; Osteoporosis; Internal medicine; Biology; Engineering","authors":[{"name":"Pierfrancesco Tassone","is_ca":false},{"name":"P. Tagliaferri","is_ca":false},{"name":"Marco Rossi","is_ca":false},{"name":"Teresa Calimeri","is_ca":false},{"name":"Alessandra Bulotta","is_ca":false},{"name":"A. Abbruzzese","is_ca":false},{"name":"Michele Caraglia","is_ca":false},{"name":"Paola Neri","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1661181867633645,"gpt":0.3756281219796366,"spread":0.2095099352162721,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009339956,0.0008266459,0.001457436,0.001832196,0.0004486377,0.001345148,0.001210852,0.001784572,0.004227513],"category_scores_gemma":[0.0008231786,0.0002499636,0.000361108,0.002018811,0.001017938,0.002660299,0.0008275794,0.002966393,0.003802231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001027592,"about_ca_system_score_gemma":0.001150418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001276981,"about_ca_topic_score_gemma":0.002996026,"domain_scores_codex":[0.999723,0.00005751194,0.00003369127,0.0000368955,0.0001284054,0.0000204346],"domain_scores_gemma":[0.9995635,0.0002021524,0.00004778235,0.00001619961,0.0001205867,0.00004975529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006669449,0.000107003,0.0001021047,0.006818287,0.00005071847,0.0002780828,0.00009034132,0.0004438117,0.001512847,0.00883279,0.05141638,0.930281],"study_design_scores_gemma":[0.00001722052,0.00006130457,0.0002617092,0.00173811,0.00002893018,0.0008656546,0.0001002351,0.00009405176,0.0002545107,0.004461315,0.9921057,0.00001117428],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008538016,0.9963229,0.0002750513,0.001526559,0.0004035475,0.000004242238,0.000006899867,0.00001127532,0.001364153],"genre_scores_gemma":[0.0005438125,0.9967308,0.0004456259,0.0008368097,0.0003800065,0.000006924569,0.00001423561,0.000001992548,0.001039896],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004227513,"threshold_uncertainty_score":0.01414245,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1990604167","doi":"10.2174/156800908785699306","title":"Epigenetic Aberrations and Targeted Epigenetic Therapy of Esophageal Cancer","year":2008,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan; Royal University Hospital","funders":"","keywords":"Epigenetics; Malignancy; Esophageal cancer; Biology; Esophagus; Disease; Epigenetic therapy; Cancer; Cancer research; Carcinogenesis; Somatic evolution in cancer; Bioinformatics; Carcinoma; Medicine; Genetics; Pathology; Internal medicine; Gene; DNA methylation; Gene expression","authors":[{"name":"Ronghua Zhao","is_ca":false},{"name":"Alan G. Casson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04657069195341299,"gpt":0.3657157121025971,"spread":0.3191450201491841,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003485573,0.0006245376,0.00105845,0.001141648,0.0002175973,0.000449843,0.0007416554,0.0009700495,0.001781901],"category_scores_gemma":[0.000287275,0.0001774195,0.0003185849,0.00112066,0.0003037161,0.0007213324,0.0004071817,0.001196356,0.001467461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005210949,"about_ca_system_score_gemma":0.0004196273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006980557,"about_ca_topic_score_gemma":0.001811648,"domain_scores_codex":[0.9998953,0.00001971883,0.00001072234,0.00001680613,0.00004613978,0.00001122036],"domain_scores_gemma":[0.9999359,0.0000225788,0.00001117097,0.000002820194,0.00001920228,0.000008360877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000953461,0.0001003254,0.0001984543,0.004582568,0.0000691482,0.000691216,0.00004971569,0.0004961784,0.006616709,0.002674846,0.02098215,0.9634434],"study_design_scores_gemma":[0.0000477069,0.0002252317,0.001466013,0.0009358097,0.00007461986,0.005160253,0.00005051738,0.000228853,0.003034432,0.001812945,0.9869466,0.0000170532],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004437428,0.9973495,0.000297041,0.0003058727,0.0001947237,0.000006269024,0.000009910834,0.00001013968,0.001382809],"genre_scores_gemma":[0.001783804,0.9959656,0.0003328638,0.0002551262,0.00014248,0.000009568149,0.00002333049,0.000001743204,0.001485323],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001781901,"threshold_uncertainty_score":0.005961061,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2058472600","doi":"10.2174/1568009054629672","title":"Molecular Targets from VHL Studies into the Oxygen-Sensing Pathway","year":2005,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Cancer Institute; Terry Fox Foundation","keywords":"Ubiquitin ligase; Carcinogenesis; Hypoxia-inducible factors; Biology; Cancer research; Ubiquitin; Transcription factor; Vascular endothelial growth factor; Angiogenesis; Tumor suppressor gene; HIF1A; Cell biology; Cancer; Gene; Genetics; VEGF receptors","authors":[{"name":"M T Maynard","is_ca":true},{"name":"Michael Ohh","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03926531878117005,"gpt":0.3508890844591312,"spread":0.3116237656779611,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003111864,0.0008204303,0.000928055,0.00151805,0.0002674165,0.0008397439,0.0007605405,0.0009387809,0.002793694],"category_scores_gemma":[0.0003158871,0.0002004491,0.0002368431,0.001358551,0.0004901171,0.001401346,0.0005617413,0.001471444,0.003491523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007908228,"about_ca_system_score_gemma":0.0005690554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005666475,"about_ca_topic_score_gemma":0.0008984451,"domain_scores_codex":[0.9999261,0.00001093279,0.000007471133,0.00001580722,0.00003096802,0.00000870711],"domain_scores_gemma":[0.9999082,0.00002699498,0.00001165502,0.000005140009,0.0000304243,0.00001762438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001267789,0.0001096895,0.0002114861,0.006474316,0.00004922411,0.0009582564,0.0000917847,0.0007580612,0.01320529,0.01080394,0.05018827,0.917023],"study_design_scores_gemma":[0.0000150674,0.00004559287,0.0002936842,0.0005191244,0.00002067189,0.001242589,0.00003034384,0.0000749451,0.001369012,0.002398826,0.9939813,0.000008800681],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000314702,0.9953897,0.0003849652,0.000558792,0.0004872197,0.000005295392,0.00001388624,0.00001698859,0.002828442],"genre_scores_gemma":[0.001718578,0.9936904,0.0004150894,0.0004700223,0.0003215671,0.00000792039,0.00003265138,0.000002842959,0.003340969],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002793694,"threshold_uncertainty_score":0.009345829,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2098122970","doi":"10.2174/156800910791208571","title":"Pharmacological Inhibition of Poly(ADP-ribose) Polymerase (PARP) Activity in PARP-1 Silenced Tumour Cells Increases Chemosensitivity to Temozolomide and to a N3-Adenine Selective Methylating Agent","year":2010,"lang":"en","type":"article","venue":"Current Cancer Drug Targets","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Poly ADP ribose polymerase; Gene silencing; PARP inhibitor; Temozolomide; Cancer research; Biology; Chemistry; Molecular biology; Polymerase; Biochemistry; DNA; Glioma; Gene","authors":[{"name":"Lucio Tentori","is_ca":false},{"name":"Alessia Muzi","is_ca":false},{"name":"Annalisa Susanna Dorio","is_ca":false},{"name":"Marco Scarsella","is_ca":false},{"name":"Carlo Leonetti","is_ca":false},{"name":"Girish M. Shah","is_ca":true},{"name":"Weiming Xu","is_ca":false},{"name":"Emidio Camaioni","is_ca":false},{"name":"Barry Gold","is_ca":false},{"name":"R. Pellicciari","is_ca":false},{"name":"Françoise Dantzer","is_ca":false},{"name":"J. Zhang","is_ca":false},{"name":"Grazia Graziani","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02492817481694091,"gpt":0.3460347325329664,"spread":0.3211065577160255,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106471,0.0002682574,0.0002836593,0.0001333345,0.00007540595,0.0002321255,0.0001730078,0.0001785261,0.001034329],"category_scores_gemma":[0.00007645191,0.0001208375,0.0001949743,0.0001261802,0.0001934297,0.000140493,0.0001200773,0.000711335,0.0002365299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000173447,"about_ca_system_score_gemma":0.0001087132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000369602,"about_ca_topic_score_gemma":0.0004770579,"domain_scores_codex":[0.9998821,0.00001655849,0.00001511195,0.00003146598,0.00003262326,0.00002204665],"domain_scores_gemma":[0.9999137,0.00001998252,0.00002819958,0.00001204939,0.000008484954,0.00001751737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003674255,0.00001726153,0.00004913086,0.00001532484,0.00000303126,0.00001120371,0.000006804729,0.00003843299,0.9993759,0.00002033036,0.00001363501,0.0004123882],"study_design_scores_gemma":[0.000006556647,0.0002501904,0.001167965,0.000001412472,0.000007604864,0.00005590674,0.000006505077,0.0003865378,0.9975652,0.000007743446,0.0005429592,0.000001513255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952397,0.00132962,0.002189813,0.0000616422,0.00002716027,0.00002482063,0.0003013635,0.00006663903,0.0007592746],"genre_scores_gemma":[0.9947865,0.0008794796,0.002090615,0.00003594435,0.000008414247,0.00003806899,0.0005282628,0.00001624176,0.00161649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001034329,"threshold_uncertainty_score":0.003460169,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2135938421","doi":"10.2174/156800911796798922","title":"Targeting Epigenetics through Histone Deacetylase Inhibitors in Acute Lymphoblastic Leukemia","year":2011,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; Vorinostat; Histone deacetylase; Cancer research; Biology; Epigenetic therapy; Histone; Carcinogenesis; Leukemia; DNA methylation; Immunology; Cancer; Genetics; Gene expression; Gene","authors":[{"name":"A. Mummery","is_ca":true},{"name":"Aru Narendran","is_ca":false},{"name":"K.-Y. Lee","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03725352666084189,"gpt":0.3658097348730264,"spread":0.3285562082121845,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003952534,0.0007335491,0.001099397,0.001583895,0.0002171157,0.0005401666,0.0007679446,0.0007828331,0.002088331],"category_scores_gemma":[0.000362401,0.0002646559,0.0003804095,0.001825039,0.000298082,0.00089396,0.0004086681,0.00160165,0.002060282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005849074,"about_ca_system_score_gemma":0.0005128278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008338443,"about_ca_topic_score_gemma":0.002125805,"domain_scores_codex":[0.9998769,0.00001782299,0.00001681509,0.00002128925,0.00005511784,0.00001215058],"domain_scores_gemma":[0.9998753,0.00004636867,0.00002291558,0.000003930286,0.00003628526,0.00001529613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001284241,0.0001025491,0.000149021,0.007157983,0.0000804979,0.0002831573,0.00004124181,0.0004260114,0.004346085,0.002421101,0.02470931,0.9601548],"study_design_scores_gemma":[0.00006554463,0.0002362769,0.000927234,0.001019873,0.0001096035,0.001902418,0.00003577837,0.0001596903,0.001793512,0.001170335,0.9925605,0.00001926667],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003450691,0.9975431,0.0002291096,0.0002180304,0.0002110655,0.000009910423,0.00002064003,0.00001499169,0.001408058],"genre_scores_gemma":[0.001028879,0.9973311,0.0002869048,0.0001865016,0.0001167834,0.0000106961,0.00004083326,0.000002064877,0.0009961623],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002088331,"threshold_uncertainty_score":0.006986201,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4220827996","doi":"10.2174/1568009622666220317091723","title":"Current Treatment and Future Trends of Immunotherapy in BreastCancer","year":2022,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Immunotherapy; Medicine; Breast cancer; Clinical trial; Metastatic breast cancer; Oncology; Cancer; Immune checkpoint; Disease; Cancer immunotherapy; Blockade; Internal medicine","authors":[{"name":"David W. Cescon","is_ca":true},{"name":"Mitchell J. Elliott","is_ca":true},{"name":"Brooke E. Wilson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04692936036399204,"gpt":0.3792937953587975,"spread":0.3323644349948054,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001191526,0.000738715,0.001234771,0.001939705,0.0002598741,0.001243873,0.0009174974,0.001295718,0.00410877],"category_scores_gemma":[0.001178672,0.000299217,0.0006065455,0.001952694,0.0005060211,0.001816048,0.0007183566,0.002473993,0.002123634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008572564,"about_ca_system_score_gemma":0.001402357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000806623,"about_ca_topic_score_gemma":0.001719266,"domain_scores_codex":[0.9996617,0.00008084418,0.00004972024,0.00004919518,0.0001216727,0.00003690531],"domain_scores_gemma":[0.9993709,0.0003519424,0.00007308798,0.00001573951,0.0001448294,0.00004358871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001020301,0.00007004669,0.0001335524,0.01628153,0.00006597483,0.00009874692,0.0000453565,0.0003966577,0.001008008,0.00395291,0.02678045,0.9510648],"study_design_scores_gemma":[0.00003018175,0.0001426309,0.0005737286,0.005945501,0.00009779868,0.0006585505,0.00005091076,0.0001352707,0.0002826899,0.00323807,0.9888284,0.0000162596],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005836623,0.9986988,0.00008633436,0.0004200146,0.0001762042,0.000004270782,0.00001163616,0.000005492323,0.0005388507],"genre_scores_gemma":[0.0003633879,0.998629,0.0001581038,0.0003575506,0.0001694486,0.000006962386,0.00002299149,0.000001275302,0.0002914014],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00410877,"threshold_uncertainty_score":0.01374519,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2028643899","doi":"10.2174/1568009043481542","title":"Transforming Growth Factor-β Superfamily: Evaluation as Breast Cancer Biomarkers and Preventive Agents","year":2004,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"SMAD; Transforming growth factor; Smad2 Protein; Signal transduction; Growth differentiation factor; Breast cancer; Cancer research; Receptor; Biology; Transforming growth factor beta; Cancer; Cell biology; Bone morphogenetic protein; Biochemistry; Genetics; Gene","authors":[{"name":"Vandana Gupta","is_ca":false},{"name":"Damien G. Harkin","is_ca":true},{"name":"Hirofumi Kawakubo","is_ca":false},{"name":"Shyamala Maheswaran","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04984810400057648,"gpt":0.3837874887530944,"spread":0.3339393847525179,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005025829,0.0005569655,0.0008042399,0.001389334,0.0001774151,0.0006687355,0.0005429027,0.0006940105,0.003500495],"category_scores_gemma":[0.0003827001,0.0001479962,0.0002092872,0.001658228,0.0002383498,0.0007860471,0.0002997918,0.000847861,0.003072317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004466638,"about_ca_system_score_gemma":0.0006094493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005535885,"about_ca_topic_score_gemma":0.00116208,"domain_scores_codex":[0.9998996,0.0000156937,0.00001180302,0.00001673645,0.00004620718,0.000009889766],"domain_scores_gemma":[0.9998339,0.00004995492,0.00002486159,0.000005521635,0.00005890941,0.00002676565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001217628,0.00008566712,0.0001696636,0.003019958,0.00002961723,0.0002095544,0.00002864939,0.0001695583,0.004089437,0.001699184,0.01148982,0.9788871],"study_design_scores_gemma":[0.00004644622,0.0003036014,0.001142814,0.0009118544,0.00005977484,0.001751124,0.00004704551,0.0001052404,0.00250053,0.0008785822,0.992241,0.00001193742],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005630705,0.9960806,0.0001814914,0.0002209309,0.0002132231,0.000007369772,0.00001867415,0.000008360234,0.002706274],"genre_scores_gemma":[0.001881092,0.9946266,0.00042735,0.0001910869,0.0001806671,0.00001070751,0.00004430019,0.00000191129,0.002636325],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003500495,"threshold_uncertainty_score":0.01171029,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3159431400","doi":"10.2174/1568009621666210504085527","title":"Cytotoxicity and Target Modulation in Pediatric Solid Tumors by the Proteasome Inhibitor Carfilzomib","year":2021,"lang":"en","type":"article","venue":"Current Cancer Drug Targets","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Carfilzomib; Proteasome inhibitor; Rhabdomyosarcoma; Cancer research; Pediatric cancer; Cytotoxic T cell; Medicine; Cisplatin; Cytotoxicity; Proteasome; Pharmacology; Cancer; Chemotherapy; In vitro; Multiple myeloma; Sarcoma; Chemistry; Immunology; Internal medicine; Pathology","authors":[{"name":"Satbir Thakur","is_ca":true},{"name":"Yibing Ruan","is_ca":true},{"name":"Aarthi Jayanthan","is_ca":true},{"name":"Jessica Boklan","is_ca":false},{"name":"Aru Narendran","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01210334658763111,"gpt":0.2681947009137369,"spread":0.2560913543261057,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001411758,0.0002674099,0.0003093899,0.0002184099,0.0001109893,0.0002164765,0.0001383758,0.0001411637,0.000569216],"category_scores_gemma":[0.000148272,0.00006809688,0.0001798137,0.00022459,0.0001139152,0.0001116593,0.00008983922,0.0003619159,0.000132496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004508671,"about_ca_system_score_gemma":0.0003208383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001139366,"about_ca_topic_score_gemma":0.002175224,"domain_scores_codex":[0.9999033,0.00001712676,0.000007874289,0.00001348998,0.00003227688,0.00002583764],"domain_scores_gemma":[0.9999255,0.00001784894,0.00002677742,0.000006061202,0.00001134097,0.00001238651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001111798,0.0002854354,0.007245777,0.0002817671,0.00004713653,0.0003513478,0.00004012549,0.001924942,0.9518385,0.0001205952,0.0005271814,0.03622553],"study_design_scores_gemma":[0.000126425,0.005384661,0.04770103,0.00001861492,0.00008960028,0.002166458,0.00004369043,0.002298938,0.9360749,0.00005943054,0.006028691,0.000007592208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880584,0.009347109,0.001109356,0.00009119666,0.00001402014,0.00004451081,0.0003719197,0.00005454552,0.0009090092],"genre_scores_gemma":[0.9934894,0.004556681,0.0009054103,0.00002584462,0.00001134209,0.00003486644,0.0006716814,0.000007524606,0.0002973028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001139366,"threshold_uncertainty_score":0.003271282,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2065979573","doi":"10.2174/156800911795538129","title":"Redox Environment and its Meaning for Breast Cancer Cells Fate","year":2011,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Redox; Cell biology; Intracellular; Oxidative stress; Signal transduction; Biology; Biochemistry; Chemistry","authors":[{"name":"Elena A. Ostrakhovitch","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04647041995451096,"gpt":0.3082267230743886,"spread":0.2617563031198776,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000206794,0.0003102986,0.000635402,0.0005391283,0.0003120825,0.0008108527,0.000333213,0.0007432434,0.002083737],"category_scores_gemma":[0.0001822317,0.0001047881,0.000190991,0.0004613045,0.0004876289,0.0007168053,0.0004540706,0.0008483196,0.00120593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004145652,"about_ca_system_score_gemma":0.0004425964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005064363,"about_ca_topic_score_gemma":0.0007088546,"domain_scores_codex":[0.9999044,0.00001907033,0.000009309849,0.00001974338,0.00003538049,0.00001209662],"domain_scores_gemma":[0.9999508,0.00001763043,0.000007670057,0.000002595978,0.00001610322,0.000005228479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000122695,0.00005251331,0.0005030331,0.007623192,0.00005204188,0.0008581831,0.0003918797,0.0005430573,0.06512231,0.04333057,0.01752552,0.863875],"study_design_scores_gemma":[0.000005725414,0.00007531109,0.0009964372,0.0006898529,0.00003145772,0.002035917,0.0002168828,0.0001007359,0.0100284,0.007887513,0.9779117,0.00002003403],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001299808,0.9914442,0.0009505575,0.0009015448,0.000416847,0.000004783265,0.00002935447,0.00001315112,0.004939917],"genre_scores_gemma":[0.01317266,0.980893,0.0007103139,0.000354237,0.0003005098,0.000009667971,0.0000447315,0.000004389668,0.004510395],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002083737,"threshold_uncertainty_score":0.006970823,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2922582842","doi":"10.2174/1568009619666190326120833","title":"Inhibition of PI3K/mTOR Pathways with GDC-0980 in Pediatric Leukemia: Impact on Abnormal FLT-3 Activity and Cooperation with Intracellular Signaling Targets","year":2019,"lang":"en","type":"article","venue":"Current Cancer Drug Targets","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"PI3K/AKT/mTOR pathway; Protein kinase B; Leukemia; Phosphorylation; Pharmacology; Kinase; IC50; Cancer research; Chemistry; Apoptosis; Medicine; In vitro; Internal medicine; Biochemistry","authors":[{"name":"Abdulhameed Al‐Ghabkari","is_ca":true},{"name":"Maneka A. Perinpanayagam","is_ca":true},{"name":"Aru Narendran","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008210147615025337,"gpt":0.2438397091180066,"spread":0.2356295615029813,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001510375,0.0003237395,0.000376987,0.0002247114,0.0001048256,0.000196884,0.0002630559,0.0001661969,0.001058607],"category_scores_gemma":[0.0001133922,0.00007641962,0.0001733973,0.0002203003,0.0001610476,0.0001232438,0.0001526521,0.0005899228,0.0002159387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003726846,"about_ca_system_score_gemma":0.0003637735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006266847,"about_ca_topic_score_gemma":0.001490923,"domain_scores_codex":[0.9999202,0.00001308268,0.000009098,0.00001207599,0.00001938481,0.00002615537],"domain_scores_gemma":[0.9999603,0.00000796295,0.00001010627,0.00000428372,0.000005447699,0.00001185134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001851412,0.0006460209,0.003372581,0.000287676,0.00004605415,0.0002335731,0.00003536109,0.0008805231,0.960985,0.0002813794,0.0005508518,0.03082965],"study_design_scores_gemma":[0.0004574508,0.005388623,0.01647159,0.00001972767,0.0001100627,0.001119763,0.0000392516,0.001688746,0.96565,0.00007086248,0.008973325,0.0000106407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945693,0.003228011,0.0005530957,0.0001012553,0.00001895408,0.00004850856,0.000395314,0.00005707121,0.001028508],"genre_scores_gemma":[0.994875,0.002221767,0.001297851,0.00005424683,0.000009834468,0.00005819569,0.0008793595,0.00001123004,0.0005925423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001058607,"threshold_uncertainty_score":0.00354141,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2987452154","doi":"10.2174/1568009619666191111153049","title":"In Vitro Investigation Demonstrates IGFR/VEGFR Receptor Cross Talk and Potential of Combined Inhibition in Pediatric Central Nervous System Atypical Teratoid Rhabdoid Tumors","year":2019,"lang":"en","type":"article","venue":"Current Cancer Drug Targets","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Receptor tyrosine kinase; Insulin-like growth factor 1 receptor; Cancer research; Biology; Receptor; Growth factor receptor; Growth factor; Genetics","authors":[{"name":"Sunand Kannappan","is_ca":true},{"name":"Mehul Gupta","is_ca":true},{"name":"Yibing Ruan","is_ca":true},{"name":"Chunfen Zhang","is_ca":true},{"name":"Pinaki Bose","is_ca":true},{"name":"Aru Narendran","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005075892739689982,"gpt":0.2363576026332252,"spread":0.2312817098935352,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002112249,0.0002860689,0.0003039721,0.0002244202,0.0001384855,0.0002433089,0.0001774281,0.0001755565,0.001839788],"category_scores_gemma":[0.0001557628,0.00008986407,0.0003204165,0.0001859633,0.00008028498,0.0001294827,0.0001264027,0.0004411312,0.0004823017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003597543,"about_ca_system_score_gemma":0.0002790153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001630747,"about_ca_topic_score_gemma":0.003231007,"domain_scores_codex":[0.9998345,0.00002240437,0.0000138787,0.00003235713,0.00006396133,0.00003278429],"domain_scores_gemma":[0.9999193,0.00002502481,0.00001530123,0.000007993103,0.00001780281,0.00001461278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003550138,0.0002047422,0.001739752,0.000221773,0.00003937174,0.0001632067,0.00003126485,0.0009771438,0.9855791,0.000109569,0.0005089451,0.01006995],"study_design_scores_gemma":[0.00004507841,0.001931223,0.00928438,0.00001962401,0.0001038034,0.0006622017,0.00005999284,0.003101864,0.977254,0.00004429104,0.007483179,0.00001029476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792921,0.01106552,0.003546847,0.0002030261,0.00009503035,0.00008440776,0.001652502,0.0001306641,0.003929861],"genre_scores_gemma":[0.9888905,0.003219972,0.00402039,0.00007616074,0.00001741797,0.0000622903,0.001617795,0.0000164129,0.002078962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001839788,"threshold_uncertainty_score":0.006154716,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}