{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":41,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":41,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"f26855bda40e","filters":{"venue":"Current Gene Therapy"}},"results":[{"id":"W1973658117","doi":"10.2174/1566523054065039","title":"Immune Responses to Adeno-Associated Virus Vectors","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Immunogenicity; Immune system; Adeno-associated virus; Genetic enhancement; Vector (molecular biology); Biology; Transgene; Viral vector; Virology; Immunology; Capsid; Vectors in gene therapy; Antigen; Acquired immune system; Immunity; Humoral immunity; Antibody; Virus; Gene; Genetics; Recombinant DNA","retraction":null,"screen_n_in":null,"score":{"opus":0.0924212653901264,"gpt":0.4158482754005711,"spread":0.3234270100104447,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008937216,0.0009186569,0.001469432,0.0004040312,0.0001990499,0.00009312649,0.001346023,0.0005990586,0.0002947311],"category_scores_gemma":[0.0001593401,0.0008041669,0.0009884207,0.0006488943,0.0001090368,0.000004728202,0.0002811047,0.0006001749,0.0005573079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00023507,"about_ca_system_score_gemma":0.0009737635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001025139,"about_ca_topic_score_gemma":0.00005039555,"domain_scores_codex":[0.9954374,0.00107345,0.0008583518,0.001131177,0.0005413652,0.0009582262],"domain_scores_gemma":[0.9975055,0.00007334826,0.0003616607,0.001505741,0.0001951517,0.0003586061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001288499,0.0003324583,0.000002862494,0.0002148783,0.0005414278,0.000004282495,0.00003805186,0.000003711499,0.02741282,9.956137e-7,0.003459346,0.9667007],"study_design_scores_gemma":[0.0007068521,0.00252105,0.0000133461,0.0008178386,0.00009113843,0.00001068156,0.000002708477,5.667611e-7,0.02373289,0.000003528347,0.9712541,0.0008453233],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01788411,0.9790022,0.00001793848,0.00004482286,0.0008278587,0.001666454,0.0004395054,0.00006946558,0.0000476156],"genre_scores_gemma":[0.0002163563,0.9944006,0.00003903417,0.0001299875,0.001510104,0.0005070331,0.001509793,0.0002668025,0.00142029],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9677947,"threshold_uncertainty_score":0.9994409,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2048310708","doi":"10.2174/1566523024605609","title":"Intracellular Barriers to Non-Viral Gene Transfer","year":2002,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":201,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation","funders":"Medical Research Council; Vanderbilt University; Cystic Fibrosis Foundation","keywords":"Biology; Gene delivery; Plasmid; Naked DNA; Cell biology; Transgene; Genetic enhancement; DNA; Viral vector; Cytoplasm; Transfection; Gene; Genetics; Recombinant DNA","retraction":null,"screen_n_in":null,"score":{"opus":0.04388614453587219,"gpt":0.3164696479299677,"spread":0.2725835033940955,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001666634,0.0007375898,0.001037155,0.0001648066,0.0001129285,0.00006038063,0.0008091145,0.0004644304,0.0004211445],"category_scores_gemma":[0.00001457872,0.0006260693,0.0008540481,0.0001897396,0.00006561012,0.000004589136,0.00009044674,0.0003380488,0.0004394288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004314464,"about_ca_system_score_gemma":0.0002790208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004081525,"about_ca_topic_score_gemma":0.000001720986,"domain_scores_codex":[0.9975067,0.0001420402,0.0006033648,0.0009452524,0.0002251908,0.0005774306],"domain_scores_gemma":[0.9984272,0.000007730665,0.00009033488,0.0009113635,0.00008851934,0.0004749152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003732473,0.000072251,0.000001843277,0.0004126412,0.0002831268,0.000007041482,0.00009167259,0.00000603669,0.02466891,0.00000195386,0.007930495,0.9664867],"study_design_scores_gemma":[0.0003444316,0.0005011691,5.931381e-7,0.0005725981,0.000130788,0.00002214575,0.000005903232,0.000003669488,0.04559968,0.000003690927,0.9520984,0.0007169648],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01057227,0.9850916,0.001656877,0.00001690927,0.001409277,0.0009508493,0.0001814337,0.00002186534,0.00009896112],"genre_scores_gemma":[0.0006247922,0.9957088,0.00007802586,0.0002040651,0.001486092,0.000249522,0.0008292876,0.0001215973,0.0006977897],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9657698,"threshold_uncertainty_score":0.9996191,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1979845188","doi":"10.2174/156652306776359504","title":"Electroporation-Enhanced Nonviral Gene Transfer for the Prevention or Treatment of Immunological, Endocrine and Neoplastic Diseases","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Microbial Inactivation Methods","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Electroporation; Gene delivery; Genetic enhancement; Biology; Immunology; Antigen; DNA vaccination; Medicine; Virology; Gene; Immunization; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.09156169771354324,"gpt":0.4076189353977995,"spread":0.3160572376842563,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006782543,0.0003267237,0.0006060229,0.00004475986,0.00009280223,0.00002033344,0.0001401101,0.000118073,0.00002611666],"category_scores_gemma":[0.00002290161,0.0001799933,0.0003639093,0.0000989975,0.00009129055,0.000003580065,0.00001411418,0.00005424995,6.281235e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003852893,"about_ca_system_score_gemma":0.0001955695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003227649,"about_ca_topic_score_gemma":0.000004126049,"domain_scores_codex":[0.9987556,0.0002055751,0.0004191602,0.0003668754,0.00006593281,0.00018687],"domain_scores_gemma":[0.99931,0.0000997941,0.0001863585,0.0003019958,0.00007400147,0.00002783065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002810674,0.000299508,6.033688e-7,0.0003541907,0.0002471924,1.378411e-7,0.000006991129,0.000005661376,0.1729843,0.00001063637,0.00008422995,0.8257254],"study_design_scores_gemma":[0.0009806906,0.001925286,0.000007744394,0.0001072486,0.0003859392,0.000008005566,0.000002148058,0.00000403381,0.2165403,0.00002887423,0.7798111,0.0001986124],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005233214,0.9159335,0.07670277,0.0000081052,0.0001701519,0.001713284,0.0002292213,0.000008068109,0.00000168632],"genre_scores_gemma":[0.0005300982,0.99493,0.0007852481,0.000004999747,0.0003691983,0.0006622839,0.002415278,0.00003492409,0.0002680238],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8255268,"threshold_uncertainty_score":0.7339915,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2004228506","doi":"10.2174/156652308783688491","title":"Gemini Surfactants: A New Family of Building Blocks for Non-Viral Gene Delivery Systems","year":2008,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Transfection; Gene delivery; In vivo; Pulmonary surfactant; Lamellar structure; Gene; Genetic enhancement; In vitro; DNA; Chemistry; Cell biology; Computational biology; Biophysics; Biology; Biochemistry; Genetics; Crystallography","retraction":null,"screen_n_in":null,"score":{"opus":0.07393107688159231,"gpt":0.3441495735148705,"spread":0.2702184966332781,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001711523,0.0007221228,0.001579653,0.0001690361,0.00009454275,0.00003640552,0.000807014,0.0005289168,0.000007498996],"category_scores_gemma":[0.00002049577,0.0006168038,0.00109357,0.0001547138,0.00008311698,0.000007175054,0.0001360116,0.0002210822,0.000009419685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005045136,"about_ca_system_score_gemma":0.0009181501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004656346,"about_ca_topic_score_gemma":0.000001225411,"domain_scores_codex":[0.9972946,0.00009735973,0.000998633,0.000835873,0.0002456996,0.000527846],"domain_scores_gemma":[0.9980246,0.00004384628,0.0006852316,0.0008268538,0.000248941,0.0001705245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001425019,0.0001375634,0.00000926178,0.001554001,0.0007255483,0.000003489195,0.00003923548,0.00002768008,0.08439481,0.000002080498,0.01809779,0.894866],"study_design_scores_gemma":[0.0008842759,0.0007263266,0.000003276036,0.00235547,0.0001870712,0.00005845702,0.00001076061,0.00003099644,0.02237245,0.000005492882,0.9726673,0.0006981667],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05354793,0.9402552,0.002402928,0.000001826077,0.001916892,0.001357951,0.0004772792,0.0000162822,0.00002367171],"genre_scores_gemma":[0.001176848,0.9950183,0.0004799631,0.00002635943,0.001638495,0.0001730222,0.001002056,0.0001121722,0.0003727903],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9545695,"threshold_uncertainty_score":0.9996283,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2106048944","doi":"10.2174/156652311796150408","title":"Polycation-Based Gene Therapy: Current Knowledge and New Perspectives","year":2011,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hôpital du Sacré-Cœur de Montréal","funders":"Canadian Institutes of Health Research; Universidade Estadual Paulista","keywords":"Genetic enhancement; Gene delivery; Transfection; Viral vector; Vectors in gene therapy; Endosome; Gene; Computational biology; Biology; DNA; Cell biology; Intracellular; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.1299415751517722,"gpt":0.3775373899093568,"spread":0.2475958147575846,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001667918,0.0007478955,0.0008831067,0.0001967415,0.0001220503,0.00006244025,0.0005839078,0.0003184395,0.0001265416],"category_scores_gemma":[0.00001507403,0.0005972142,0.0005779145,0.0001813927,0.0001375296,0.000007160137,0.0001031573,0.0003206901,0.00009384697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004825994,"about_ca_system_score_gemma":0.001051995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001644015,"about_ca_topic_score_gemma":0.000005502678,"domain_scores_codex":[0.9977227,0.0002226782,0.0004989932,0.001008189,0.0001305887,0.000416878],"domain_scores_gemma":[0.9984061,0.00002354972,0.000325375,0.0008281909,0.0001776717,0.000239176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006975594,0.0003190477,0.00001864644,0.0003579862,0.0002311234,4.029517e-7,0.0002393963,2.269711e-7,0.001254171,0.00002174618,0.004761922,0.9927256],"study_design_scores_gemma":[0.0007314063,0.0004430795,0.00002674152,0.0008055528,0.0001019852,0.000009717121,0.00001478745,0.000002718574,0.005656471,0.00003315464,0.9914922,0.0006821625],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002587301,0.9944939,0.0006192427,0.0000135743,0.001260623,0.0008095856,0.0000878059,0.0000325922,0.00009538458],"genre_scores_gemma":[0.0003155048,0.9963419,0.0001059072,0.00003113778,0.001821275,0.0001608257,0.000802762,0.0001003835,0.0003203225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9920434,"threshold_uncertainty_score":0.9996479,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2140137267","doi":"10.2174/156652306775515510","title":"Synthetic and Natural Polycations for Gene Therapy: State of the Art and New Perspectives","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hôpital du Sacré-Cœur de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Arthritis Society","keywords":"Genetic enhancement; Natural (archaeology); Computational biology; Medicine; Gene; Biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.04386803663991975,"gpt":0.3323648828359524,"spread":0.2884968461960327,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001092679,0.0002734642,0.0003945777,0.00004500989,0.0001060624,0.00002446305,0.0001608462,0.00009667512,0.000002075429],"category_scores_gemma":[0.00001277673,0.0001704156,0.0002431157,0.00008257957,0.0001653025,0.000002124341,0.00005758038,0.0001067377,5.144219e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001112022,"about_ca_system_score_gemma":0.0001752477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005459887,"about_ca_topic_score_gemma":0.000003311947,"domain_scores_codex":[0.9989136,0.00006897109,0.0002615126,0.0005056048,0.00008702427,0.0001632395],"domain_scores_gemma":[0.999219,0.00001297092,0.000236007,0.0004022928,0.00008503637,0.00004470554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003512507,0.00006442583,0.000007450104,0.0002403644,0.0001453034,2.884913e-8,0.00007284617,0.000001862828,0.02006892,0.00001853006,0.0009367213,0.9784084],"study_design_scores_gemma":[0.0003241675,0.0001971436,0.0001535012,0.0001717217,0.00008477052,0.00001843417,0.000009832303,0.000003239546,0.01145134,0.0001020143,0.9872628,0.0002210741],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01252783,0.9856626,0.0003011436,0.00007022939,0.0003977907,0.0009408528,0.00008538402,0.000005271937,0.000008904995],"genre_scores_gemma":[0.00165806,0.9961147,0.0002095242,0.000009297625,0.0005507258,0.00005758656,0.0001327642,0.00004167007,0.001225612],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.986326,"threshold_uncertainty_score":0.6949347,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2010502399","doi":"10.2174/1566523054546189","title":"Transcriptionally Targeted Adenovirus Vectors","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Enhancer; Biology; Viral vector; Genetic enhancement; Adenoviridae; Gene; Reporter gene; Gene delivery; Vector (molecular biology); Computational biology; Promoter; Adenovirus genome; Molecular biology; Gene expression; Genetics; Recombinant DNA","retraction":null,"screen_n_in":null,"score":{"opus":0.09186519329482874,"gpt":0.3912072206450932,"spread":0.2993420273502645,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004260569,0.0008412725,0.001119374,0.0002686553,0.0001516724,0.0000677083,0.001066338,0.00046062,0.0007324617],"category_scores_gemma":[0.00001854289,0.0007240837,0.001089298,0.0003686385,0.0001499497,0.000005642189,0.00008106121,0.0006054164,0.0002953784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001131409,"about_ca_system_score_gemma":0.0009580243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002547259,"about_ca_topic_score_gemma":0.00002234763,"domain_scores_codex":[0.9964836,0.000489693,0.0007081465,0.001039104,0.0005358758,0.0007435764],"domain_scores_gemma":[0.9982442,0.00002375654,0.0002587298,0.001061758,0.0001466209,0.0002649813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004200605,0.0002419519,0.000001213171,0.0004869027,0.0004478831,0.000002588452,0.00002104737,0.000006012122,0.0127651,0.000004391239,0.003542909,0.98206],"study_design_scores_gemma":[0.0007653078,0.001244282,0.000002790046,0.000425884,0.0000959407,0.00002019241,0.000001503908,0.000001330711,0.006028211,0.000009933148,0.9906577,0.0007468635],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001289791,0.9959708,0.00007797386,0.00002721491,0.0009271032,0.001214721,0.0003419927,0.00005709854,0.00009334779],"genre_scores_gemma":[0.0000726672,0.9924515,0.00008257038,0.0001339881,0.00291914,0.0003815203,0.003118583,0.0002262308,0.0006137596],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9871148,"threshold_uncertainty_score":0.999521,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2155621040","doi":"10.2174/156652310791321288","title":"Bioprocessing of Baculovirus Vectors: A Review","year":2010,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Biotechnology Research Institute","funders":"GlaxoSmithKline","keywords":"Bioprocess; Commercialization; Biotechnology; Biochemical engineering; Baculoviridae; Computational biology; Biology; Computer science; Recombinant DNA; Engineering; Business; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.06169982797149409,"gpt":0.4012116516460338,"spread":0.3395118236745397,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001868638,0.0004925128,0.001130613,0.0000610702,0.0000794728,0.00002306094,0.0004614485,0.000349949,0.0001363347],"category_scores_gemma":[0.00005384532,0.0003648738,0.0009199961,0.0002355015,0.0001011691,0.000003512956,0.0001203343,0.0003265958,0.00003034955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000126412,"about_ca_system_score_gemma":0.0003243347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003370144,"about_ca_topic_score_gemma":0.000001018916,"domain_scores_codex":[0.9981597,0.000146308,0.0006563152,0.0005648236,0.0001960191,0.0002768373],"domain_scores_gemma":[0.9982864,0.00001338249,0.0006332056,0.0007936383,0.0001387974,0.0001346213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001015877,0.000142994,0.000003202025,0.01697015,0.00009624699,5.956556e-7,0.000003368566,1.150038e-7,0.005711878,0.000001953719,0.005056761,0.9720026],"study_design_scores_gemma":[0.00018564,0.0001653642,9.382782e-7,0.01907978,0.0001999688,0.00001842545,4.342005e-7,1.525721e-7,0.005372982,0.00001125388,0.9745763,0.0003887385],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002764693,0.9975053,0.00003893133,0.000004694347,0.001211857,0.0006997192,0.0001338322,0.00001994141,0.0001092185],"genre_scores_gemma":[0.0000245048,0.9978988,0.00005174239,0.00009005804,0.0009394347,0.000183566,0.0006733749,0.00007853586,0.00006001435],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9716138,"threshold_uncertainty_score":0.9998803,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101997181","doi":"10.2174/1566523054546198","title":"Genetic Manipulation of Human Embryonic Stem Cells: A System to Study Early Human Development and Potential Therapeutic Applications","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Embryonic stem cell; Regenerative medicine; Biology; Stem cell; Cellular differentiation; Computational biology; Directed differentiation; Induced pluripotent stem cell; Gene; Genetics; Cell biology","retraction":null,"screen_n_in":null,"score":{"opus":0.08299404506824358,"gpt":0.3701679422256626,"spread":0.287173897157419,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003594123,0.000537239,0.0008929665,0.0002734987,0.0002739372,0.00006498645,0.0006355824,0.0002299224,0.000008298241],"category_scores_gemma":[4.632306e-7,0.0004818804,0.0002352699,0.0002445942,0.00005260268,0.000004078031,0.0002539344,0.0002128958,0.00003220291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001187281,"about_ca_system_score_gemma":0.0001889344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005251262,"about_ca_topic_score_gemma":0.000006357265,"domain_scores_codex":[0.9969793,0.0003866638,0.000872197,0.0009031986,0.0004463313,0.000412317],"domain_scores_gemma":[0.9983994,0.00000946506,0.0004115782,0.0008583188,0.0001415819,0.0001797018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001694146,0.0004621314,0.00007465818,0.002030196,0.0004303845,0.00000191134,0.0001380523,0.00001640955,0.02006154,0.000009925515,0.00001395342,0.9767439],"study_design_scores_gemma":[0.002885466,0.002607063,0.002403058,0.00193457,0.0007761536,0.00004925705,0.0001444011,0.00001440119,0.01954546,0.000004709356,0.9678432,0.001792237],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2415403,0.7537535,0.0007395115,0.000001263123,0.00008112854,0.003834262,0.00001877057,0.00002166716,0.000009595391],"genre_scores_gemma":[0.1870839,0.8105323,0.0001375152,0.000003761602,0.0003952678,0.001382068,0.0001742283,0.0001115265,0.0001793753],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9749517,"threshold_uncertainty_score":0.9997633,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2034858347","doi":"10.2174/1566523054546233","title":"Retrovirus Silencing and Vector Design: Relevance to Normal and Cancer Stem Cells?","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children; SickKids Foundation","funders":"Hospital for Sick Children; Stem Cell Network","keywords":"Biology; Gene silencing; Stem cell; Epigenetics; Retrovirus; Vector (molecular biology); Chromatin; DNA methylation; Histone; Variegation (histology); Viral vector; RNA interference; Cell biology; Cancer research; Genetics; Gene; Gene expression; RNA","retraction":null,"screen_n_in":null,"score":{"opus":0.09692672178414298,"gpt":0.3854021522531232,"spread":0.2884754304689802,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004416642,0.0006027788,0.000856323,0.0001426791,0.0001466609,0.00008032264,0.0004152062,0.0002958097,0.0000441585],"category_scores_gemma":[0.00001045549,0.0005196547,0.0001813576,0.0002149217,0.0001206772,0.000007415663,0.0001918808,0.0003723448,0.00003235848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009967468,"about_ca_system_score_gemma":0.0004439366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008174759,"about_ca_topic_score_gemma":0.00002372211,"domain_scores_codex":[0.997354,0.0003643095,0.0004370683,0.0009702881,0.000278983,0.0005953382],"domain_scores_gemma":[0.998713,0.00005248959,0.0001919855,0.0006379457,0.00009223982,0.0003123248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004473577,0.00003648927,0.000002505808,0.0006713393,0.0001311845,0.000001994335,0.00005046198,0.00002045883,0.05337971,6.210046e-7,0.0008247257,0.9444332],"study_design_scores_gemma":[0.0004814498,0.001508037,0.000002057702,0.0008593349,0.00006097672,0.00001250894,0.000004205301,0.000009413362,0.0879791,0.000001523461,0.9085084,0.0005729877],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01563274,0.9822258,0.0002194623,0.00003110886,0.0004286329,0.001306864,0.0001255637,0.00002219683,0.00000766676],"genre_scores_gemma":[0.0003017604,0.9972265,0.0002575915,0.0001130274,0.001261123,0.0003859103,0.00004250972,0.0001292678,0.0002823055],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9438602,"threshold_uncertainty_score":0.9997255,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2064274745","doi":"10.2174/1566523054546215","title":"The Use of Oncolytic Vaccinia Viruses in the Treatment of Cancer: A New Role for an Old Ally?","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Oncolytic virus; Vaccinia; Virotherapy; Virus; Virology; Immune system; Biology; Lytic cycle; Cancer; Poxviridae; Immunology; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.2429138507340362,"gpt":0.4716437130514456,"spread":0.2287298623174094,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003705324,0.0004474778,0.0008735593,0.00009780671,0.0000844498,0.00004284052,0.0009060601,0.0002042752,0.00001694592],"category_scores_gemma":[0.00001757514,0.0002408473,0.0006141935,0.0002257374,0.00008824791,0.000005911823,0.00003186938,0.0001306628,0.000001904777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000101969,"about_ca_system_score_gemma":0.001085299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000189899,"about_ca_topic_score_gemma":0.002204607,"domain_scores_codex":[0.9976999,0.0004623717,0.000687347,0.0004736188,0.0002634421,0.000413379],"domain_scores_gemma":[0.9979783,0.0001965508,0.0004284437,0.001204078,0.0001039229,0.00008868762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001553796,0.0006833107,0.00001799158,0.000195521,0.0003646595,1.980105e-7,0.0002048446,0.00004228935,0.004604258,0.000005636046,0.0006562397,0.9916713],"study_design_scores_gemma":[0.001378222,0.008073414,0.000007940353,0.0002985132,0.0001349608,0.000001690802,0.00001326104,0.00001659143,0.0152815,0.0000151834,0.9745511,0.0002276514],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03629242,0.9605066,0.000009556092,0.00004218137,0.0001567869,0.002723371,0.0002609701,0.000004891975,0.000003194101],"genre_scores_gemma":[0.0001773193,0.9974843,0.00005784824,0.00005951804,0.0008024509,0.0009973503,0.0002101707,0.0000750589,0.0001359981],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9914436,"threshold_uncertainty_score":0.9821467,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136412920","doi":"10.2174/1566523013349002","title":"Cancer Gene Therapy by Adenovirus-Mediated Gene Transfer","year":2001,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"Genetic enhancement; Oncolytic virus; Viral vector; Gene delivery; Oncolytic adenovirus; Cancer; Vectors in gene therapy; Vector (molecular biology); Virotherapy; Gene; Biology; Tumor suppressor gene; Cancer research; Medicine; Virus; Virology; Carcinogenesis; Recombinant DNA; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.08548273130189618,"gpt":0.3912909669189722,"spread":0.305808235617076,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0006753267,0.001721862,0.002193304,0.0003535148,0.0002888917,0.0001381026,0.001933595,0.001139197,0.001334765],"category_scores_gemma":[0.00001670908,0.001433395,0.001409434,0.0009673884,0.0003207043,0.00001340301,0.0001387975,0.001041693,0.000271175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000222918,"about_ca_system_score_gemma":0.001454436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003575896,"about_ca_topic_score_gemma":0.00004437856,"domain_scores_codex":[0.993243,0.0009301289,0.001253104,0.002046207,0.0009294214,0.001598184],"domain_scores_gemma":[0.9967909,0.00006344981,0.0003220547,0.001960564,0.0002909021,0.0005720935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001118011,0.0005010806,0.000006934951,0.0003621346,0.001184583,0.00001004734,0.00004832777,0.000005189972,0.1737443,4.875906e-7,0.01020635,0.8128125],"study_design_scores_gemma":[0.002400714,0.001730429,0.000001303008,0.000383811,0.0001197198,0.00003021743,0.000002944368,0.000002665544,0.1698383,0.000005897999,0.8241839,0.001300091],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0176034,0.9757094,0.0002603698,0.00007300587,0.001235372,0.002654697,0.002301707,0.0001070796,0.00005495493],"genre_scores_gemma":[0.0001250608,0.9844676,0.00002806083,0.0004411806,0.002773063,0.001719985,0.008956629,0.0005552353,0.000933163],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8139775,"threshold_uncertainty_score":0.9995782,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136010083","doi":"10.2174/156652305774329230","title":"Recent Advances in the Development of Adenovirus- and Poxvirus- Vectored Tuberculosis Vaccines","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"","keywords":"Virology; Vaccinia; Vaccination; Tuberculosis vaccines; Tuberculosis; DNA vaccination; Medicine; Immune system; Modified vaccinia Ankara; BCG vaccine; Viral vector; Diva; Immunology; Virus; Biology; Mycobacterium tuberculosis; Recombinant DNA; Immunization; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.1372392263648071,"gpt":0.4431205479033706,"spread":0.3058813215385635,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001213759,0.0004745992,0.001959667,0.0003809722,0.00007237699,0.00001272411,0.0003550688,0.0002089312,0.000140624],"category_scores_gemma":[0.0001773658,0.0002611466,0.0002657877,0.000549744,0.00009467192,0.00007217266,0.00007447098,0.0006279737,0.00002695019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001481432,"about_ca_system_score_gemma":0.0004724911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003907968,"about_ca_topic_score_gemma":0.00005387812,"domain_scores_codex":[0.9967932,0.0006255802,0.001165642,0.000514592,0.0003884487,0.0005125923],"domain_scores_gemma":[0.9985177,0.0004334148,0.0003040855,0.000503405,0.00009396089,0.0001474708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001049899,0.0002878421,0.0002541627,0.002381662,0.0001732259,0.00000270008,0.0003715644,3.177094e-7,0.00001276931,0.00001018325,0.0005115408,0.9958891],"study_design_scores_gemma":[0.0007671544,0.0001749624,0.001317167,0.002833436,0.0001259237,0.00004196202,0.00002838752,0.000002119715,0.00003121386,0.00001612215,0.9944303,0.0002312553],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002439962,0.9952624,0.000005598281,0.0004437871,0.0002270826,0.001457682,0.00002356228,0.00001846363,0.0001214311],"genre_scores_gemma":[0.00006845399,0.9984269,0.0003176679,0.0001480438,0.0004449392,0.0003568691,0.0001847282,0.00004190985,0.00001044528],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9956578,"threshold_uncertainty_score":0.9999841,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2081611049","doi":"10.2174/1566523052997460","title":"Viral Vectors for Cancer Gene Therapy: Viral Dissemination and Tumor Targeting","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Oncolytic virus; Virotherapy; Genetic enhancement; Virus; Viral vector; Cancer; Vector (molecular biology); Virology; Clinical trial; Gene; Medicine; Cancer research; Biology; Bioinformatics; Genetics; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.05607985630219525,"gpt":0.4150865633594765,"spread":0.3590067070572812,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006238078,0.0008068294,0.001050675,0.0001956523,0.0002545824,0.0001066183,0.0005797006,0.0003334832,0.00008485133],"category_scores_gemma":[0.00003985481,0.0006681487,0.0006006413,0.0001820546,0.0001453056,0.00001196638,0.0001146182,0.000358617,0.00000898055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001278144,"about_ca_system_score_gemma":0.0004635933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005904712,"about_ca_topic_score_gemma":0.00001306172,"domain_scores_codex":[0.9968466,0.0003186211,0.0006578833,0.001081176,0.0003383754,0.0007573602],"domain_scores_gemma":[0.9985356,0.0000678933,0.0004130011,0.0005999132,0.0001848477,0.0001987978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000647412,0.0001394065,0.000008516456,0.0005452069,0.0003051032,8.922231e-7,0.00005767457,0.000004848693,0.06569579,0.000002800493,0.001589681,0.9310027],"study_design_scores_gemma":[0.001016399,0.001430744,0.000004602197,0.0004713256,0.0000753533,0.000007686291,0.000005270402,0.00002540797,0.07355406,0.00001737502,0.9226624,0.0007293674],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04632809,0.9501048,0.0001308902,0.00003904677,0.0006920143,0.002193866,0.0004661432,0.00003673963,0.000008420423],"genre_scores_gemma":[0.0006559461,0.9912523,0.0002169313,0.00008399553,0.003490334,0.001562064,0.002260735,0.0002302401,0.0002474244],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9302733,"threshold_uncertainty_score":0.999577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2148795794","doi":"10.2174/1566523024605582","title":"Oncolytic Viruses: Programmable Tumour Hunters","year":2002,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Regional Cancer Foundation","funders":"","keywords":"Oncolytic virus; Picornavirus; Virology; Virus; Biology; Cancer; Cancer research; Genome; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.1338375007407413,"gpt":0.4132714413518869,"spread":0.2794339406111456,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004899444,0.0009439833,0.001383014,0.0002606261,0.0001751932,0.0001473688,0.001302902,0.0004745037,0.0003233811],"category_scores_gemma":[0.00002860632,0.0007959089,0.001080357,0.0004713133,0.0001861611,0.00000652534,0.0002171776,0.0006342477,0.0006089651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573665,"about_ca_system_score_gemma":0.0006437362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003856062,"about_ca_topic_score_gemma":0.00001198056,"domain_scores_codex":[0.9959729,0.0005181453,0.000770199,0.001204828,0.0005165893,0.001017327],"domain_scores_gemma":[0.9977233,0.00003037322,0.0003893714,0.001395899,0.0001375097,0.0003235834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002651383,0.0003712004,0.000001809575,0.001237132,0.0004217226,0.00000760992,0.00002166283,0.000002828378,0.002749391,0.000001774314,0.005284282,0.9896355],"study_design_scores_gemma":[0.0008918275,0.00263187,2.175007e-7,0.001139762,0.0001201487,0.0000332907,0.000005514954,0.0000061217,0.006277357,0.000007286901,0.9880611,0.0008254763],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007869941,0.9956378,0.00004826809,0.00001255372,0.0007996909,0.002219086,0.0001122549,0.00007276124,0.0003105671],"genre_scores_gemma":[0.00003846723,0.9954161,0.00007753607,0.0001107215,0.001518602,0.0008689543,0.0006768433,0.0002759321,0.00101682],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9888099,"threshold_uncertainty_score":0.9994492,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2768540553","doi":"10.2174/1566523217666171121165046","title":"Therapeutic Applications of CRISPR/Cas for Duchenne Muscular Dystrophy","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Dystrophin; Utrophin; CRISPR; Duchenne muscular dystrophy; Exon skipping; Muscular dystrophy; Biology; Genome editing; Exon; Bioinformatics; Medicine; Genetics; Gene; Alternative splicing","retraction":null,"screen_n_in":null,"score":{"opus":0.09907920268079923,"gpt":0.4626543951073407,"spread":0.3635751924265415,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001712801,0.0004097497,0.00084088,0.00008958253,0.0001066037,0.00002911058,0.0006371647,0.0002568896,0.000009751277],"category_scores_gemma":[0.00001404898,0.0003486336,0.0008164977,0.00006792114,0.00007677433,0.000001983638,0.00006799144,0.0001355177,0.00000619176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001693927,"about_ca_system_score_gemma":0.0001597395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001971546,"about_ca_topic_score_gemma":8.903318e-7,"domain_scores_codex":[0.9986084,0.00004197001,0.0004445624,0.0005043726,0.0001156097,0.000285134],"domain_scores_gemma":[0.9982088,0.00001936632,0.000343686,0.001216187,0.0001317997,0.0000801702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001190846,0.00008199165,0.000001099613,0.002582379,0.0003152096,1.285381e-7,0.0000111891,0.00001042967,0.003033704,0.00003791973,0.0002111884,0.9937028],"study_design_scores_gemma":[0.0003869324,0.0001602993,0.000003544986,0.0003665351,0.0002616081,0.000006821323,0.000002186466,0.000005236123,0.008412214,0.00005603644,0.9899936,0.0003450271],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003620784,0.8800097,0.1177703,0.000005776238,0.0004078314,0.001538667,0.0001984305,0.00001237888,0.00002065868],"genre_scores_gemma":[0.0003411315,0.9958025,0.0006277281,0.000006917334,0.0009518439,0.001234647,0.0008340505,0.00009242142,0.0001087796],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9933578,"threshold_uncertainty_score":0.9998966,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2134559385","doi":"10.2174/156652309790031148","title":"Addressing the Challenge: Current and Future Directions in Ovarian Cancer Therapy","year":2009,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Ovarian cancer; Cancer therapy; Medicine; Current (fluid); Oncology; Cancer; Internal medicine; Engineering","retraction":null,"screen_n_in":null,"score":{"opus":0.2433365094971075,"gpt":0.4492741907744034,"spread":0.2059376812772959,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002629788,0.0007023933,0.001616162,0.0002561908,0.0002138839,0.00008347586,0.0002044049,0.0002231564,0.0002538133],"category_scores_gemma":[0.000004087233,0.0003876189,0.0004709567,0.0005280126,0.00008194844,0.00005800007,0.00003116902,0.0009346768,0.0000102041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003964044,"about_ca_system_score_gemma":0.0006051703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004149912,"about_ca_topic_score_gemma":0.00003755717,"domain_scores_codex":[0.9975933,0.0002664107,0.0005995961,0.0007696973,0.0003205508,0.0004504766],"domain_scores_gemma":[0.9986358,0.00009056008,0.0003178074,0.000716064,0.00006827763,0.0001715462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004349524,0.0008703481,0.00006435939,0.0009882991,0.0003204853,0.000009099032,0.0004716728,1.594455e-7,3.863434e-7,0.00007899568,0.0009485235,0.9962042],"study_design_scores_gemma":[0.002261593,0.0002067797,0.001555729,0.01064084,0.0003983475,0.00003125559,0.00001209016,0.000001547824,0.000004271975,0.0000707506,0.9844647,0.0003520925],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005902469,0.9905561,0.000002359712,0.003772724,0.002840611,0.002488074,0.00007950933,0.00005073713,0.0001508177],"genre_scores_gemma":[0.00003731333,0.9931434,0.00002149135,0.0001288923,0.004913205,0.001515007,0.0001311713,0.00008112717,0.0000283882],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9958521,"threshold_uncertainty_score":0.9998575,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2162735751","doi":"10.2174/156652306775515538","title":"Targeting DNA Repair Proteins: A Promising Avenue for Cancer Gene Therapy","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Montreal General Hospital","funders":"","keywords":"DNA repair; Homologous recombination; Genetic enhancement; Cancer; Cancer research; Biology; Gene; DNA; Cancer cell; DNA damage; Genome instability; Radiation therapy; Medicine; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.06154839178120794,"gpt":0.3574347242085726,"spread":0.2958863324273647,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005594926,0.0008733661,0.00125412,0.0001190705,0.0002162093,0.00006979376,0.0005902075,0.000545078,0.00002510246],"category_scores_gemma":[0.00003384902,0.0007364642,0.001308522,0.0001932242,0.00006613184,0.000006680531,0.0001078656,0.0002923871,0.000009615825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001263739,"about_ca_system_score_gemma":0.0006968405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001386462,"about_ca_topic_score_gemma":0.000004187619,"domain_scores_codex":[0.9966635,0.0002275901,0.0008301107,0.001268613,0.000278348,0.0007318595],"domain_scores_gemma":[0.9980184,0.00001982467,0.0007107848,0.0009370823,0.000190024,0.0001238644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008759042,0.0002085332,0.000003030739,0.00215111,0.0004229911,0.000002283225,0.00002952822,0.000007599543,0.0952379,0.000007423613,0.0033142,0.8985278],"study_design_scores_gemma":[0.0009001197,0.0003556204,6.26115e-7,0.001367663,0.000110318,0.00001132408,0.000001819397,0.00002038527,0.08989654,0.00006732073,0.9065002,0.000768022],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002705601,0.9879876,0.001509265,0.00001234163,0.001370137,0.005867147,0.0003935998,0.000139621,0.00001472504],"genre_scores_gemma":[0.00001812881,0.9838968,0.004084877,0.0000574643,0.00362128,0.005293496,0.002342331,0.0003012421,0.0003843624],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.903186,"threshold_uncertainty_score":0.9995086,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012596257","doi":"10.2174/156652307780859008","title":"Development of Ribozyme-Based Gene-Inactivations; The Example of the Hepatitis Delta Virus Ribozyme","year":2007,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Ribozyme; Mammalian CPEB3 ribozyme; RNA interference; RNA; Biology; Ligase ribozyme; Gene; RNase P; Computational biology; Functional genomics; VS ribozyme; Genetics; Molecular biology; Genomics; Genome","retraction":null,"screen_n_in":null,"score":{"opus":0.1191725938611862,"gpt":0.3575407891227057,"spread":0.2383681952615195,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004498011,0.0004228551,0.0006834922,0.00009626322,0.0001629648,0.00001544899,0.001009832,0.0002500877,0.00005130079],"category_scores_gemma":[0.00002374392,0.0002455554,0.0005889371,0.0002687137,0.0001824757,0.000003515239,0.0001602145,0.0002259552,0.000009910455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005271415,"about_ca_system_score_gemma":0.0009283056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001297352,"about_ca_topic_score_gemma":0.0001054596,"domain_scores_codex":[0.9978524,0.0002135758,0.0008734721,0.0004495121,0.0003171722,0.0002938826],"domain_scores_gemma":[0.9978041,0.0000565462,0.0007593794,0.001092221,0.000236006,0.00005172564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003983034,0.0001921645,0.0000652688,0.0005381402,0.0003072558,3.033573e-7,0.0000895968,0.000009881331,0.02967768,0.00001304575,0.00150995,0.9675569],"study_design_scores_gemma":[0.0001862441,0.00007408467,0.00008350231,0.0005298245,0.00006568927,0.000003100606,0.000004050694,0.000002122636,0.3146027,0.000007051469,0.68424,0.000201594],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05451415,0.941623,0.002223806,0.000009724377,0.0006111941,0.0007593483,0.0002165647,0.000006713282,0.00003553068],"genre_scores_gemma":[0.001835232,0.9962946,0.0005544483,0.0000677024,0.0002538142,0.0001313066,0.0007512274,0.00004803216,0.00006362097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9673553,"threshold_uncertainty_score":0.9999996,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2129090621","doi":"10.2174/1566523053544272","title":"Adenovirus-mediated Transgene-engineered Dendritic Cell Vaccine of Cancer","year":2005,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Saskatchewan Cancer Agency; Defence Research and Development Canada","funders":"","keywords":"Antigen; Gene delivery; Ex vivo; Viral vector; Biology; Dendritic cell; Genetic enhancement; Virology; Vector (molecular biology); Transgene; Antigen-presenting cell; T cell; Immunotherapy; In vivo; Immunology; Immune system; Gene; Recombinant DNA; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0583760517344819,"gpt":0.3836259103633745,"spread":0.3252498586288926,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003282757,0.0008308269,0.001541355,0.0003124221,0.0000689626,0.00002465279,0.001025136,0.000535704,0.0005248145],"category_scores_gemma":[0.00001522253,0.0007229408,0.0008765275,0.0004991561,0.00008064363,0.000004971243,0.0000803376,0.0005228844,0.00007202894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007844759,"about_ca_system_score_gemma":0.0009397757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007487629,"about_ca_topic_score_gemma":0.00006526414,"domain_scores_codex":[0.9966425,0.0003395787,0.0009546067,0.0008723385,0.0004578602,0.0007330765],"domain_scores_gemma":[0.9980417,0.00004791839,0.0003639893,0.001082821,0.000208184,0.0002553748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004460094,0.0003440677,0.00000502719,0.002303173,0.0004789398,0.000002260528,0.00002284198,0.00003770662,0.07480737,5.535342e-7,0.001244105,0.9203079],"study_design_scores_gemma":[0.001564152,0.001083432,0.000002634513,0.0007861273,0.0002007741,0.000005681885,0.00000205067,0.000006944548,0.1155193,0.000001388355,0.8801984,0.0006291108],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009037307,0.9880853,0.00007061951,0.00001842748,0.0005882418,0.001298493,0.0008298124,0.000033957,0.00003788342],"genre_scores_gemma":[0.000757702,0.9948895,0.00005480835,0.00004401236,0.00142316,0.0004538842,0.001795325,0.0002382942,0.0003433437],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9196789,"threshold_uncertainty_score":0.9995221,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1989866840","doi":"10.2174/1566523214666140612154929","title":"Impact of DNA Vector Topology on Non-Viral Gene Therapeutic Safety and Efficacy","year":2014,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Gene delivery; Genetic enhancement; Vector (molecular biology); Viral vector; Plasmid; Vectors in gene therapy; Transfection; Computational biology; Gene; Biology; Transgene; DNA; Recombinant DNA; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.04278012071427435,"gpt":0.371397564655355,"spread":0.3286174439410806,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001885513,0.0005808719,0.001287307,0.0001228538,0.00006073064,0.00001843084,0.0004313829,0.00039605,0.00004656069],"category_scores_gemma":[0.000014288,0.0004109688,0.0008095221,0.00008710245,0.0001560071,0.000002605004,0.00009336152,0.0002469601,0.00002732874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003841106,"about_ca_system_score_gemma":0.0001964333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008926152,"about_ca_topic_score_gemma":0.000001052184,"domain_scores_codex":[0.9980513,0.000240212,0.0005698875,0.000640932,0.0001290062,0.0003686488],"domain_scores_gemma":[0.9986444,0.00004767354,0.0003771288,0.0007433904,0.00007551034,0.0001119472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003358292,0.0001962461,0.00002884131,0.0003744303,0.0006411183,8.721562e-7,0.00002555206,0.000003505996,0.01542279,0.000008677493,0.0004080226,0.9825541],"study_design_scores_gemma":[0.0015488,0.005459607,0.0009752789,0.0009152504,0.0002579101,0.00003871524,0.000001820995,0.000006861415,0.01218491,0.00002000786,0.9778217,0.0007691588],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09912206,0.8993969,0.0001926782,0.00001036342,0.0005763281,0.0005298671,0.0001250733,0.000008620266,0.00003813435],"genre_scores_gemma":[0.02180523,0.9766193,0.00001504342,0.00006232887,0.0007268246,0.00003163663,0.0006149905,0.00006410697,0.00006054446],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9817849,"threshold_uncertainty_score":0.9998342,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1981960353","doi":"10.2174/156652312800099607","title":"Ex Vivo Gene Therapy and Vision","year":2012,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Ex vivo; Genetic enhancement; Clinical trial; Medicine; Multiple sclerosis; Blindness; Bioinformatics; In vivo; Biology; Pathology; Gene; Immunology; Optometry; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.07179217953378633,"gpt":0.3690908774524253,"spread":0.2972986979186389,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002458414,0.0005713605,0.0007363632,0.00009487588,0.0000991662,0.00005487999,0.0003206931,0.000335805,0.0001099825],"category_scores_gemma":[0.000005572996,0.0004241391,0.0003344356,0.0001226108,0.00008852826,0.000005764802,0.0001155569,0.000178595,0.00005154242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001659738,"about_ca_system_score_gemma":0.0001493319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001712275,"about_ca_topic_score_gemma":7.042641e-7,"domain_scores_codex":[0.9982371,0.000152339,0.000410391,0.000594394,0.0001905927,0.0004151481],"domain_scores_gemma":[0.9990653,0.00001349533,0.0002348135,0.0004751738,0.00005121334,0.0001599534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004736722,0.0001070454,0.00004126523,0.0004190344,0.0001318923,5.541138e-7,0.00002825381,5.241535e-8,0.002983999,0.000006854799,0.001946008,0.9942877],"study_design_scores_gemma":[0.0005577963,0.0002010988,0.00004610067,0.0003219749,0.00005362683,0.00001813024,0.000002684906,3.116677e-7,0.002621828,0.00002177494,0.9956102,0.0005444624],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004498188,0.9935598,0.0000845455,0.0000137506,0.0008247815,0.0007050359,0.00002840106,0.0000202251,0.0002652864],"genre_scores_gemma":[0.00009425735,0.997511,0.0001923965,0.00006472068,0.0007633605,0.00008788877,0.000807491,0.00008553272,0.0003933104],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9937432,"threshold_uncertainty_score":0.9998211,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2009066388","doi":"10.2174/156652308785160674","title":"CCR5 as Target for HIV-1 Gene Therapy","year":2008,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Chemokine receptor; Chemokine receptor CCR5; Biology; CXCR4; Chemokine; C-C chemokine receptor type 6; Immune system; Virology; CCR1; Receptor; Immunology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.1116089137515411,"gpt":0.3891599429324618,"spread":0.2775510291809207,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002024822,0.0008660987,0.001912668,0.0002814253,0.0004120386,0.0000314995,0.0007448529,0.0005731458,0.00180118],"category_scores_gemma":[0.00002405388,0.0005935993,0.00128334,0.0002260388,0.0002425694,0.00005121206,0.00006890664,0.0006169753,0.008755122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693164,"about_ca_system_score_gemma":0.0008521011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009245058,"about_ca_topic_score_gemma":6.850538e-7,"domain_scores_codex":[0.9968171,0.0005228576,0.0006572874,0.0008712719,0.0001033266,0.001028131],"domain_scores_gemma":[0.9983124,0.0002780417,0.0003132426,0.0008588792,0.0001281597,0.000109337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002156374,0.0007353471,0.000005495558,0.0003502019,0.001697744,0.00001242255,0.00009795981,1.621475e-7,0.000301167,0.00002698283,0.04986013,0.9466968],"study_design_scores_gemma":[0.003854683,0.001018723,0.000002908299,0.0004319142,0.00007276989,0.0002144106,0.000002950147,9.366018e-8,0.002877382,0.00008006804,0.9908997,0.0005443343],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001767597,0.9919044,0.0001570891,0.00005888078,0.00179863,0.00347496,0.00212265,0.0001221131,0.000184471],"genre_scores_gemma":[0.000008191011,0.9788147,0.0001846335,0.00004484771,0.0004545756,0.002088092,0.01512598,0.0001332418,0.003145797],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9461524,"threshold_uncertainty_score":0.9996516,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144019145","doi":"10.2174/156652312802083558","title":"Combating Hepatitis C Virus by Targeting MicroRNA-122 Using Locked Nucleic Acids","year":2012,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research; American Liver Foundation; National Institutes of Health; Life Sciences Research Foundation; National Institute of Allergy and Infectious Diseases; Amgen; School of Medicine, Stanford University","keywords":"Nucleic acid; microRNA; Oligonucleotide; Biology; Translation (biology); Locked nucleic acid; Gene; Gene expression; Genetic enhancement; Virus; Virology; Computational biology; Messenger RNA; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.05375332492623973,"gpt":0.3340718919343247,"spread":0.2803185670080849,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003348676,0.0006891354,0.000880904,0.00009746374,0.000209515,0.00007228785,0.0004680405,0.0004354941,0.00009992132],"category_scores_gemma":[0.00002476614,0.0006534577,0.0005845714,0.0001892316,0.00009195164,0.000009648071,0.0001874736,0.0002874356,0.0000492127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001439205,"about_ca_system_score_gemma":0.0002167921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002506193,"about_ca_topic_score_gemma":0.000001936699,"domain_scores_codex":[0.9973311,0.000378676,0.00075763,0.0006932279,0.0002289734,0.0006103375],"domain_scores_gemma":[0.9982961,0.00001971613,0.0007419836,0.0006357284,0.0001074047,0.0001990552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001373306,0.0002512347,0.0001207856,0.0014728,0.0002573376,7.842607e-7,0.00002714386,0.00000234499,0.2515341,0.000001642385,0.002560163,0.743758],"study_design_scores_gemma":[0.000496212,0.00004538102,0.000007612066,0.0009818402,0.0002681016,0.00001641251,0.00000196773,0.00002649854,0.02691052,0.000003806927,0.9705303,0.0007113615],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0380589,0.9586297,0.001138382,0.000003379431,0.0009734029,0.0007922844,0.0003559348,0.00003730697,0.00001076162],"genre_scores_gemma":[0.0009341037,0.9917287,0.0009383854,0.00003278443,0.001419892,0.00006725863,0.0046595,0.000192684,0.00002675691],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9679701,"threshold_uncertainty_score":0.9995916,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2768713198","doi":"10.2174/1566523217666171122094629","title":"CRISPR/Cas9 Gene Editing: From Basic Mechanisms to Improved Strategies for Enhanced Genome Engineering In Vivo","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Jewish General Hospital; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Genome editing; Cas9; Homologous recombination; Genome; Biology; Computational biology; Genome engineering; Genetics; Gene; Homology directed repair; DNA repair; DNA mismatch repair","retraction":null,"screen_n_in":null,"score":{"opus":0.050504660936735,"gpt":0.3814422626638076,"spread":0.3309376017270726,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002314254,0.0007235566,0.00113501,0.0001813066,0.00008661157,0.0001419124,0.000769719,0.0003824882,0.00002506314],"category_scores_gemma":[0.00004737262,0.0007039159,0.0004932312,0.00009664657,0.00001862684,0.00000808806,0.0001535896,0.0002470763,0.000007469536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006299823,"about_ca_system_score_gemma":0.0002493106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001335385,"about_ca_topic_score_gemma":0.00002052508,"domain_scores_codex":[0.9976493,0.00003606865,0.0006095134,0.000938905,0.0001411656,0.0006250865],"domain_scores_gemma":[0.9984941,0.00002939792,0.0002406736,0.0009764666,0.00007956025,0.0001797598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002781169,0.00004377974,1.114518e-7,0.0008719788,0.000152812,0.000001353547,0.00006830927,0.0003641578,0.6186576,0.00001279068,0.0001032813,0.379696],"study_design_scores_gemma":[0.0007322585,0.0002635686,0.000002398929,0.0006862104,0.00007790769,0.000003118267,0.000014222,0.00008058586,0.2349987,0.00005475018,0.7623845,0.0007018017],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001725809,0.7949791,0.1999235,0.000006078581,0.001512113,0.001415829,0.0003919262,0.00003214223,0.00001355929],"genre_scores_gemma":[0.001744611,0.9896507,0.003939308,0.00002110543,0.002495858,0.001037074,0.000871535,0.0001770133,0.00006279343],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7622812,"threshold_uncertainty_score":0.9995412,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2088886521","doi":"10.2174/156652306777934838","title":"Gene Silencing in the Development of Personalized Cancer Treatment: The Targets, the Agents and the Delivery Systems","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Gene silencing; RNA interference; Genetic enhancement; Cancer; Biology; Ribozyme; Gene delivery; Computational biology; Context (archaeology); Cancer research; Gene; Bioinformatics; RNA; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.08404303058456694,"gpt":0.3495110406987746,"spread":0.2654680101142077,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007270748,0.0004535416,0.0006966777,0.00004487092,0.0002795611,0.00006643659,0.000819723,0.0001450011,0.000009840314],"category_scores_gemma":[0.000007544732,0.0001613917,0.0003736782,0.0001516332,0.0002771734,0.00000365932,0.00009738708,0.0001954778,0.000003592999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006866451,"about_ca_system_score_gemma":0.0004072578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002712313,"about_ca_topic_score_gemma":0.0001237815,"domain_scores_codex":[0.9976619,0.0007420452,0.0006373301,0.0004049155,0.0002527309,0.0003010009],"domain_scores_gemma":[0.9987561,0.000111542,0.0004181229,0.0006140098,0.00007466429,0.00002559477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001214304,0.0001218976,0.0000534961,0.0004787612,0.000723869,0.000001390233,0.002985915,0.00003798026,0.0005586047,0.00001567828,0.001574241,0.9933267],"study_design_scores_gemma":[0.001071076,0.00008391269,0.00008124424,0.0007372659,0.0002413996,0.00001666324,0.0003327569,0.00002733943,0.001295015,0.000005874306,0.9958575,0.0002498935],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07270489,0.9251663,0.00003261359,0.00005520917,0.0004793568,0.001449888,0.00007783608,0.000003390481,0.00003051172],"genre_scores_gemma":[0.01121654,0.9868194,0.000009207321,0.00008578305,0.0004497722,0.0009911141,0.0002335207,0.00003038989,0.0001642009],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9942833,"threshold_uncertainty_score":0.6581363,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2770152187","doi":"10.2174/1566523217666171121164132","title":"New Developments in CRISPR/Cas-based Functional Genomics and their Implications for Research Using Zebrafish","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Zebrafish; Functional genomics; Genomics; Computational biology; Biology; Genetics; Computer science; Genome; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.3688961522785418,"gpt":0.5229553943083401,"spread":0.1540592420297983,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003972755,0.000289737,0.0004485638,0.0001732864,0.0001973754,0.00007049678,0.0003097266,0.0002129382,0.00000400116],"category_scores_gemma":[0.00003553681,0.0002552021,0.0001692195,0.00008798892,0.00004515614,0.000002846601,0.00009712672,0.0001976389,0.000001383403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008323418,"about_ca_system_score_gemma":0.001010584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007279674,"about_ca_topic_score_gemma":0.0000141988,"domain_scores_codex":[0.9987093,0.00005758938,0.0003188966,0.0005030055,0.00006433685,0.0003468624],"domain_scores_gemma":[0.9991395,0.00004121449,0.0001130596,0.0004938177,0.000101416,0.0001109442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001829265,0.00003070234,0.00003498351,0.0004749842,0.00006130274,6.973432e-8,0.0000200117,0.00004073578,0.005393295,0.000009673754,0.0008476255,0.9930683],"study_design_scores_gemma":[0.0005344189,0.00004978225,0.0002828952,0.000360091,0.00001842385,0.000007136607,0.000003052483,0.00003613732,0.00310187,0.00006978639,0.9952624,0.0002739851],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007634806,0.9375924,0.06029167,0.00002219589,0.0003087365,0.0009017895,0.0001031849,0.000006156612,0.00001039707],"genre_scores_gemma":[0.0003363857,0.9955832,0.002354678,0.00001211012,0.0005690287,0.0002053036,0.0008313575,0.00006223941,0.00004570667],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9944148,"threshold_uncertainty_score":0.99999,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2111274962","doi":"10.2174/156652306775515592","title":"RNA Based Gene Therapy for Dominantly Inherited Diseases","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"","keywords":"Genetic enhancement; RNA; Genetics; Gene; Biology; Computational biology; Medicine; Bioinformatics","retraction":null,"screen_n_in":null,"score":{"opus":0.06942449154776023,"gpt":0.3622432113396636,"spread":0.2928187197919034,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001610873,0.0008506022,0.001242183,0.0001676823,0.0001487542,0.00008381387,0.000750868,0.0004409793,0.00005028561],"category_scores_gemma":[0.00001806676,0.000667741,0.001378846,0.0001961167,0.0001073151,0.000005642019,0.00006411473,0.0001897891,0.00002943723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000441105,"about_ca_system_score_gemma":0.0005402213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009038785,"about_ca_topic_score_gemma":0.000003125901,"domain_scores_codex":[0.9973062,0.0001956938,0.000708919,0.001000762,0.0002145331,0.0005738995],"domain_scores_gemma":[0.9981915,0.00004557089,0.0004369501,0.000965772,0.000205368,0.0001548213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002936752,0.0004023315,0.00001131042,0.0007791633,0.0002788513,0.000002505568,0.000004690909,0.000005937355,0.0100775,0.000001859877,0.01609108,0.9720511],"study_design_scores_gemma":[0.001667435,0.0007501947,0.0000167212,0.0006981426,0.0001708872,0.00000583527,0.000001416433,0.00001418788,0.02135983,0.00002305412,0.9744616,0.0008307414],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005055615,0.9886857,0.001784049,0.00001555029,0.001218792,0.001891795,0.001282828,0.00004024699,0.00002543262],"genre_scores_gemma":[0.000223932,0.985949,0.0002569489,0.0001753525,0.002030607,0.001046822,0.009837418,0.0001626463,0.0003173039],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9712204,"threshold_uncertainty_score":0.9995774,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3112267878","doi":"10.2174/1566523220666201214115024","title":"CRISPR/Cas9 Technology as a Modern Genetic Manipulation Tool for Recapitulating of Neurodegenerative Disorders in Large Animal Models","year":2020,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"CRISPR; Cas9; Genome editing; Neuroscience; Biology; Disease; Computational biology; Animal model; Transgene; Gene knockin; Bioinformatics; Gene; Medicine; Genetics; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.04132951322094621,"gpt":0.3783901069833089,"spread":0.3370605937623627,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001279407,0.0004890832,0.0009157353,0.0002247946,0.00005146662,0.00001631183,0.0003368162,0.0003704823,0.000004900265],"category_scores_gemma":[0.00004260155,0.0004837661,0.0003787076,0.0002882685,0.00003622856,0.000005530067,0.0001255302,0.0002400082,0.000001719627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003031958,"about_ca_system_score_gemma":0.000167666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002428348,"about_ca_topic_score_gemma":0.00001284049,"domain_scores_codex":[0.9979208,0.00008437333,0.0007160089,0.0007480209,0.0001372485,0.0003935376],"domain_scores_gemma":[0.9991326,0.00002169003,0.0002824856,0.0004355597,0.00007287832,0.00005480664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006953427,0.0001083161,0.00003332025,0.001409021,0.0001033217,9.237161e-7,0.0001184776,0.005039898,0.01078278,0.0001264138,0.00002573815,0.9821823],"study_design_scores_gemma":[0.003182705,0.002004733,0.00005317912,0.00179655,0.0003323262,0.00003644777,0.00004572445,0.0671168,0.02233031,0.002701347,0.8984845,0.001915411],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01183759,0.8705457,0.1157038,0.00001802,0.000211375,0.001542244,0.000107516,0.00002304787,0.00001072391],"genre_scores_gemma":[0.04646999,0.9502483,0.002026491,0.00001085598,0.0002497414,0.0004389609,0.0004352785,0.0001117191,0.0000086602],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9802669,"threshold_uncertainty_score":0.9997614,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2055923087","doi":"10.2174/156652306779010651","title":"Ex Vivo Modification of Cells to Induce a Muscle-Based Expression","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"","keywords":"Ex vivo; In vivo; Cell biology; Expression (computer science); Myocyte; Biology; Molecular biology; Chemistry; Computer science; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.07223260897788635,"gpt":0.3602783947431259,"spread":0.2880457857652395,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001106889,0.0003312806,0.0005731873,0.0001031721,0.00004289112,0.00000728185,0.0003563356,0.0003230308,0.00003167249],"category_scores_gemma":[0.000008617181,0.0002758776,0.0003449489,0.0001442568,0.00005145734,0.000001724242,0.00005114558,0.0001298628,0.00001784797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001355666,"about_ca_system_score_gemma":0.0001935523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006434207,"about_ca_topic_score_gemma":0.000001238741,"domain_scores_codex":[0.9985751,0.0001830307,0.0003992964,0.0005133629,0.0001154891,0.0002137043],"domain_scores_gemma":[0.9988807,0.00001694346,0.0003022334,0.0006596475,0.00006833067,0.0000720937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004790106,0.0002235844,7.808086e-7,0.0007927279,0.00002093015,8.89951e-8,0.000008601929,0.0000659857,0.3831719,0.000002552761,0.004533046,0.611132],"study_design_scores_gemma":[0.0003002603,0.0001588388,0.000008887202,0.0005336173,0.00003096843,1.827903e-7,0.000001459623,0.000002660062,0.1715275,0.0000124608,0.8271713,0.0002519003],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01128481,0.98584,0.001508843,0.000005897687,0.000390326,0.0007513745,0.0001317489,0.00001118658,0.00007580817],"genre_scores_gemma":[0.002653379,0.9954824,0.0001798323,0.00004431245,0.000269358,0.0001701018,0.001103438,0.00004411635,0.00005302603],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8226382,"threshold_uncertainty_score":0.9999694,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2073376039","doi":"10.2174/156652306777934810","title":"Gene Therapy in Lung Transplantation","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Genetic enhancement; Lung transplantation; Transplantation; Medicine; Lung; Immunology; Gene delivery; Cancer research; Biology; Gene; Surgery; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.1390016206961581,"gpt":0.4453754765306657,"spread":0.3063738558345076,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004363099,0.0006474069,0.001902609,0.0004874302,0.00006297042,0.00003306486,0.0002173794,0.0003158985,0.0001350486],"category_scores_gemma":[0.000003766306,0.0004717833,0.0007110339,0.0005249754,0.00004790951,0.00007329979,0.000004717643,0.000563894,0.00003163147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001461655,"about_ca_system_score_gemma":0.0003320668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000338852,"about_ca_topic_score_gemma":0.00001071675,"domain_scores_codex":[0.9972318,0.0003841077,0.0009705168,0.0005978923,0.0003875152,0.0004282028],"domain_scores_gemma":[0.9989096,0.0001863003,0.0002801284,0.0004493233,0.00005768383,0.0001169781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001573599,0.0002428911,0.0005725331,0.007066559,0.0001512663,0.00006118973,0.0002325092,0.000002043482,0.00006782728,0.00002144094,0.0001382931,0.9912861],"study_design_scores_gemma":[0.004660208,0.0002043005,0.002931278,0.006537452,0.0005894994,0.0001998348,0.00000329951,0.000008006056,0.0005850237,0.0000544842,0.9835998,0.0006268479],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001656246,0.9927739,0.001969642,0.00004087744,0.001122962,0.002027344,0.0001662073,0.00009971661,0.0001431115],"genre_scores_gemma":[0.0000288905,0.9934012,0.002326316,0.00008814572,0.0007841658,0.0002632474,0.002848756,0.0001150632,0.0001441961],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9906592,"threshold_uncertainty_score":0.9997734,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2097524729","doi":"10.2174/156652310793180698","title":"Retinal Blinding Disorders and Gene Therapy - Molecular and Clinical Aspects","year":2010,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Retinitis pigmentosa; Blinding; Retinal Disorder; Retinal degeneration; Retina; Retinal; Genetic enhancement; Retinal pigment epithelium; Biology; Gene therapy of the human retina; Macular degeneration; Bioinformatics; Gene; Neuroscience; Medicine; Genetics; Clinical trial; Ophthalmology","retraction":null,"screen_n_in":null,"score":{"opus":0.05041948407339245,"gpt":0.3799895948101813,"spread":0.3295701107367889,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000517127,0.0006729395,0.0009650382,0.0001275016,0.0001507835,0.00009978242,0.0003535809,0.0006060547,0.00002308952],"category_scores_gemma":[0.00004845569,0.0005433685,0.0004356852,0.0001485601,0.0003000759,0.000005925603,0.0001707174,0.0005896043,0.000008815721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001049254,"about_ca_system_score_gemma":0.000264467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002824228,"about_ca_topic_score_gemma":0.000005607671,"domain_scores_codex":[0.9974154,0.0002610871,0.0006566187,0.001007795,0.0002185916,0.0004405254],"domain_scores_gemma":[0.9988261,0.0000430145,0.0003460326,0.0005051778,0.00005324746,0.0002263869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007869759,0.0001163624,0.0005171192,0.0002642062,0.0002088326,0.000003219761,0.00001804969,4.859143e-8,0.001396577,0.0000307281,0.0001685247,0.9971976],"study_design_scores_gemma":[0.001183773,0.0004109794,0.0001901873,0.0003884416,0.00009396999,0.00003545648,0.000005194413,0.000001124563,0.0009619549,0.000222511,0.9958054,0.0007009868],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06495937,0.9329756,0.0001542124,0.00004333364,0.0007731785,0.0008388006,0.00001818388,0.00002216273,0.0002151229],"genre_scores_gemma":[0.0007987148,0.9975016,0.0004140116,0.00007970932,0.0004865145,0.00007569794,0.000485155,0.0001015371,0.00005705167],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9964966,"threshold_uncertainty_score":0.9997018,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1971886268","doi":"10.2174/156652306776359513","title":"Immuno-Isolation in Cancer Gene Therapy","year":2006,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Cancer Research Institute","keywords":"Angiostatin; Immunotherapy; Genetic enhancement; Cancer immunotherapy; Cancer research; Ex vivo; Cancer cell; Immune system; Biology; Cancer; Immunology; Angiogenesis; Medicine; In vivo; Biotechnology; Gene; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.1352387313997239,"gpt":0.408646586342633,"spread":0.2734078549429091,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002409199,0.0005366763,0.001701224,0.0003825778,0.00005577823,0.00002949199,0.0001572369,0.0002681383,0.0006616033],"category_scores_gemma":[0.00001333717,0.0003880114,0.0005043185,0.000542495,0.00004809342,0.00005479649,0.00001677159,0.0004448542,0.0001154177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003300277,"about_ca_system_score_gemma":0.0005358531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009694485,"about_ca_topic_score_gemma":0.000003304139,"domain_scores_codex":[0.9978925,0.0001706005,0.0007529264,0.000494751,0.000302474,0.0003867781],"domain_scores_gemma":[0.9988469,0.00008622376,0.0003298551,0.0005522486,0.00008538389,0.00009941425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007131565,0.0003399059,0.0003916509,0.001033907,0.0001702957,0.000002780171,0.00003930828,0.000002179662,0.0003422653,0.000006175738,0.002071895,0.9955283],"study_design_scores_gemma":[0.002361421,0.0001616282,0.0005231372,0.003768645,0.00015688,0.000009199292,0.000001855244,0.00002191093,0.0003273407,0.00002673005,0.9922816,0.0003596301],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004316401,0.9918452,0.00004667202,0.00004048553,0.001670102,0.001506298,0.00005034785,0.0000888461,0.0004356646],"genre_scores_gemma":[0.00004540025,0.9962093,0.00009142025,0.0001372321,0.001186017,0.0005754884,0.0009966113,0.00009054338,0.0006680427],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9951687,"threshold_uncertainty_score":0.9998572,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2054795427","doi":"10.2174/156652309787354658","title":"HIV-1 Gene Therapy at Pre-Integration and Provirus DNA Levels","year":2009,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Ontario HIV Treatment Network","keywords":"Provirus; Genetic enhancement; Integrase; Virology; Integrase inhibitor; Lentivirus; Biology; Virus; Antiretroviral therapy; RNA interference; Reverse transcriptase; Gene; Medicine; Immunology; Human immunodeficiency virus (HIV); Viral load; Viral disease; Genome; RNA; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.1001161783463163,"gpt":0.394191460212059,"spread":0.2940752818657428,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000652071,0.001113333,0.001389001,0.0002551184,0.0002846938,0.0001381705,0.0008448507,0.0006715992,0.000161081],"category_scores_gemma":[0.00002567013,0.0008737486,0.0006719746,0.0003065611,0.0002056789,0.00001247363,0.0001833412,0.0005406484,0.0001036858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001714917,"about_ca_system_score_gemma":0.0006233319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004130006,"about_ca_topic_score_gemma":0.00001937854,"domain_scores_codex":[0.9956278,0.0007056059,0.0008285802,0.001466603,0.0005407403,0.0008306667],"domain_scores_gemma":[0.9975778,0.00003974,0.0004638907,0.001422029,0.0001922193,0.0003043424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009667617,0.0002224128,0.000004808841,0.0003076078,0.0002909224,0.000003456273,0.0000605451,0.000001650942,0.1042324,0.000003231707,0.001699356,0.8922068],"study_design_scores_gemma":[0.001337828,0.002599145,0.00002190923,0.0004748872,0.00006191628,0.00004903646,0.000002077638,0.000005612677,0.1776893,0.0000345899,0.8169143,0.0008094092],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03477532,0.9612933,0.0002197191,0.00005134497,0.0004185017,0.002723681,0.0003869107,0.00006016491,0.00007108905],"genre_scores_gemma":[0.0004021392,0.9934432,0.0001405773,0.0001677331,0.001439079,0.0004930065,0.002504436,0.0002069365,0.00120289],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8913974,"threshold_uncertainty_score":0.9993713,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4402192295","doi":"10.2174/0115665232294935240826061311","title":"Recent Advances in Therapeutics and Manufacturing Processes of Recombinant Adeno-Associated Virus for the Treatment of Lung Diseases","year":2024,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Feldan (Canada)","funders":"","keywords":"Genetic enhancement; Cystic fibrosis; Medicine; Lung; Gene delivery; Adeno-associated virus; Clinical trial; Immunology; Disease; Bioinformatics; Recombinant DNA; Biology; Vector (molecular biology); Gene; Pathology; Internal medicine; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.07757918336534553,"gpt":0.4116906513443414,"spread":0.3341114679789959,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002058171,0.000444514,0.0009249423,0.0001356605,0.00005931594,0.00002325508,0.0003330479,0.0001637351,0.000006790367],"category_scores_gemma":[0.00001700674,0.0002599142,0.0003265814,0.0002093757,0.0001349276,0.000005126833,0.00004658976,0.0001157239,5.614536e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009263178,"about_ca_system_score_gemma":0.0004481783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002901907,"about_ca_topic_score_gemma":0.00008490571,"domain_scores_codex":[0.9982282,0.0001780069,0.0005799758,0.0004960588,0.0001933105,0.0003244532],"domain_scores_gemma":[0.9989042,0.0001580816,0.0003433696,0.0004307104,0.000110625,0.00005296976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000636834,0.0007369329,0.00002013898,0.004902998,0.0006927996,6.161437e-7,0.00009560772,0.000005443267,0.0003892626,6.397427e-7,0.00004674778,0.992472],"study_design_scores_gemma":[0.0009300776,0.003146036,0.000008201857,0.001680797,0.0005224568,0.000001616325,0.00001434969,0.000008435286,0.03660711,0.0000618854,0.9567581,0.0002609297],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01069506,0.9862581,0.000009087129,0.00002292134,0.0005393646,0.002031535,0.0004331434,0.000008948914,0.000001812028],"genre_scores_gemma":[0.0004444421,0.998126,0.000005970965,0.00000704044,0.0001660804,0.0007317165,0.0003931279,0.00007817908,0.00004739892],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.992211,"threshold_uncertainty_score":0.9999853,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2018930141","doi":"10.2174/1566523013348382","title":"Gene Therapy to Overcome Drug Resistance in Cancer: Targeting Key Regulators of the Apoptotic Pathway","year":2001,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Apoptosis; Drug resistance; Chemotherapy; Cancer; Cancer research; Genetic enhancement; Biology; Gene; Drug; Cancer cell; Bioinformatics; Pharmacology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0363379645074192,"gpt":0.3159300019155997,"spread":0.2795920374081805,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004115045,0.0005088839,0.0008871717,0.0001262958,0.00009861471,0.00002231325,0.0006191076,0.0002732608,0.00003656999],"category_scores_gemma":[0.00001436189,0.0003416009,0.0005417661,0.0005503034,0.00005626622,0.000004154717,0.000120759,0.0002310802,0.000003112384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001063606,"about_ca_system_score_gemma":0.0003203115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002789609,"about_ca_topic_score_gemma":0.00004497465,"domain_scores_codex":[0.9975773,0.000290732,0.0007464776,0.0006786355,0.0003032544,0.0004036266],"domain_scores_gemma":[0.9984374,0.00001786987,0.0005128005,0.0008446147,0.00009527141,0.00009204507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000701661,0.0001406723,0.00003029027,0.0006728537,0.0001002454,8.634725e-7,0.0001554194,0.00007723163,0.03047875,0.00005062571,0.0007225796,0.9675003],"study_design_scores_gemma":[0.0004733933,0.00004959877,0.00006604766,0.001576976,0.0000264646,0.000002064719,0.000003975024,0.000002611265,0.04282385,0.00008807736,0.9544885,0.0003984209],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03143044,0.9657577,0.0000953491,0.00004543468,0.001245891,0.001311118,0.0000671486,0.0000111052,0.00003577515],"genre_scores_gemma":[0.001361926,0.9963872,0.0002804001,0.00004725984,0.0006230674,0.000130542,0.0002258803,0.00009091517,0.000852768],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9671019,"threshold_uncertainty_score":0.9999036,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2586627998","doi":"10.2174/1566523217666170102111251","title":"Antibody Delivery Mediated by Recombinant Adeno-associated Virus for the Treatment of Various Chronic and Infectious Diseases","year":2017,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"National Research Council Canada; Université Laval","funders":"","keywords":"Monoclonal antibody; Medicine; Antibody; Virus; Immunology; Virology; Genetic enhancement; Adeno-associated virus; Vector (molecular biology); Immune system; Disease; Recombinant DNA; Biology; Pathology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.06438738618525104,"gpt":0.3993344334318936,"spread":0.3349470472466426,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002658563,0.0006157414,0.001237994,0.0001000377,0.0003631443,0.00007124581,0.0005846652,0.0003408369,0.00002043805],"category_scores_gemma":[0.00006083143,0.0003968901,0.0006672085,0.0001079181,0.0002733303,0.000005111448,0.00007630063,0.0001528353,0.000004997674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002026523,"about_ca_system_score_gemma":0.000794815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005354095,"about_ca_topic_score_gemma":0.0001201719,"domain_scores_codex":[0.9977263,0.0003415298,0.000517124,0.0006777627,0.0002267761,0.0005105456],"domain_scores_gemma":[0.9978309,0.0001866324,0.0006485956,0.00102189,0.0001657128,0.0001462275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004121014,0.001091842,0.00003419639,0.0005980583,0.001752818,0.000001355819,0.00002795459,0.000001044174,0.01140463,5.818871e-7,0.0008201546,0.9838552],"study_design_scores_gemma":[0.002864438,0.0105633,0.00001929192,0.0004646333,0.0005409313,0.000005708923,0.000001702599,0.00001841032,0.003914933,0.0000140542,0.9811618,0.0004308151],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0124366,0.9823135,0.00004558562,0.0000131772,0.0007538058,0.002558966,0.001852529,0.00002181502,0.000003987321],"genre_scores_gemma":[0.001200353,0.9904959,0.000001712713,0.00001054169,0.0003678928,0.0007773282,0.006876905,0.0001134016,0.0001559395],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9834244,"threshold_uncertainty_score":0.9998483,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3198950915","doi":"10.2174/1566523221666210916153051","title":"Treatment of GM2 Gangliosidosis in Adult Sandhoff Mice Using an IntravenousSelf-Complementary Hexosaminidase Vector","year":2021,"lang":"en","type":"article","venue":"Current Gene Therapy","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"","keywords":"Sandhoff disease; Gangliosidosis; Hexosaminidase; Cohort; Toxicity; Internal medicine; Medicine; Pharmacology; Biology; Endocrinology; Enzyme; Disease; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.08643990539476974,"gpt":0.3717611663735641,"spread":0.2853212609787943,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008413631,0.0002258687,0.0004552268,0.0001891843,0.00005848506,0.00001671911,0.000113123,0.00005483717,0.0005274323],"category_scores_gemma":[0.00001677772,0.0001965163,0.0001327712,0.0004913487,0.00006112093,0.00007774824,0.00002823628,0.0001133663,0.000007940996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003623498,"about_ca_system_score_gemma":0.0003312534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004772198,"about_ca_topic_score_gemma":0.0001576482,"domain_scores_codex":[0.9982712,0.0001773611,0.0003799732,0.0004053536,0.0003712087,0.0003949407],"domain_scores_gemma":[0.9990382,0.00004458443,0.00008004952,0.0004204844,0.0002376294,0.0001790502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001172008,0.01085597,0.05681378,0.0001538187,0.0002596111,0.0003633665,0.005297617,0.00002812699,0.7402084,0.00002805528,0.00005692906,0.1847623],"study_design_scores_gemma":[0.01244098,0.002794572,0.0328973,0.000148573,0.00008060016,0.0001123903,0.001258703,0.00113551,0.9472421,0.00003578197,0.001550583,0.0003029353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858101,0.01286836,0.00005932573,0.0003149064,0.0002128438,0.0006043495,0.00006030619,0.00002620986,0.00004357753],"genre_scores_gemma":[0.9920692,0.006330247,0.0008936191,0.00009703641,0.0002132675,0.00004051556,0.0002996971,0.00004028576,0.00001610962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2070336,"threshold_uncertainty_score":0.8013704,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2040575854","doi":"10.2174/156652309787354667","title":"A Possible Approach for Stem Cell Gene Therapy of Fanconi Anemia","year":2009,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Fanconi anemia; Genetic enhancement; Gene; Stem cell; Anemia; Medicine; Cancer research; Genetics; Biology; Computational biology; Bioinformatics; DNA repair; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.05281824577955205,"gpt":0.3684791430286231,"spread":0.315660897249071,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002223778,0.0006142186,0.001130097,0.0001160649,0.0000574355,0.00002668323,0.0005484336,0.0004030461,0.000008166669],"category_scores_gemma":[0.00000240101,0.000507539,0.0008184789,0.0001726456,0.0000366751,0.00000237612,0.00004691599,0.0001885267,0.000002408185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002477262,"about_ca_system_score_gemma":0.0002514041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001167423,"about_ca_topic_score_gemma":2.029663e-7,"domain_scores_codex":[0.9980006,0.00007569137,0.0006227113,0.0006956179,0.0001679304,0.0004375111],"domain_scores_gemma":[0.9986351,0.00001771252,0.0003262884,0.0008035082,0.0001029474,0.0001144247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005143679,0.0002283961,0.000001997493,0.002249306,0.0001258827,3.034574e-7,0.00003879296,0.00007767337,0.02371338,0.000003521272,0.0008042541,0.9727051],"study_design_scores_gemma":[0.0009668639,0.0005386951,0.000002269984,0.0002648875,0.00007035021,0.00001194975,0.000006401373,0.00002243053,0.1469932,0.000006311082,0.8506043,0.0005123499],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001080294,0.9735256,0.02307139,0.000001954645,0.000410086,0.001589038,0.0001835114,0.00002253808,0.0001156219],"genre_scores_gemma":[0.000277845,0.9941744,0.002809336,0.00001867499,0.0007879208,0.0002888438,0.001287849,0.0001124857,0.000242618],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9721927,"threshold_uncertainty_score":0.9997376,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4413998755","doi":"10.2174/0115665232381943250825055516","title":"Tailored Therapies for Hereditary Diabetes: Unraveling the Genetic Underpinnings of MODY and Neonatal Diabetes","year":2025,"lang":"en","type":"article","venue":"Current Gene Therapy","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Nutrition International","funders":"","keywords":"Medicine; HNF1A; Genetic testing; Precision medicine; Diabetes mellitus; Glycemic; Type 2 diabetes; Disease; Personalized medicine; Maturity onset diabetes of the young; Sulfonylurea; Bioinformatics; Medical genetics; Genetics; Internal medicine; Gene; Endocrinology; Biology; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.02492359229603153,"gpt":0.2848277755870276,"spread":0.2599041832909961,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002079855,0.000202185,0.0003770434,0.0001236786,0.0001317779,0.00002277977,0.0001177258,0.00006277487,0.00003643733],"category_scores_gemma":[0.00007434223,0.0001322329,0.0001325402,0.0002089409,0.0002213024,0.00004169566,0.0000318621,0.0001151854,0.00000151197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002236257,"about_ca_system_score_gemma":0.00009819662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003552203,"about_ca_topic_score_gemma":3.457382e-7,"domain_scores_codex":[0.9989436,0.00004622405,0.0003113671,0.000260481,0.0001574659,0.0002809013],"domain_scores_gemma":[0.9990276,0.0003754612,0.00009830097,0.0003031108,0.0001314673,0.00006403011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004458221,0.000284885,0.1656825,0.0006756918,0.001225984,6.811301e-7,0.001877672,0.00005003735,0.1748181,0.000556346,0.003995141,0.650387],"study_design_scores_gemma":[0.01849406,0.00236415,0.2718182,0.001489358,0.0008643289,0.000004530516,0.002196762,0.03347079,0.5908138,0.02140041,0.05620001,0.0008835922],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8973592,0.09850881,0.001595008,0.001163554,0.0005555968,0.0006918026,0.00001971372,0.00004594717,0.0000603789],"genre_scores_gemma":[0.9944299,0.002935779,0.001074364,0.0009686684,0.0002357334,0.0001610653,0.00004483628,0.00002443584,0.0001252471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6495035,"threshold_uncertainty_score":0.5392302,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2314619822","doi":"10.2174/1566523043346516","title":"Getting to the Heart of the Matter: Exploring Opportunities for Gene Therapy Treatment of Dystrophic Cardiomyopathy","year":2004,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"","keywords":"Cardiomyopathy; Muscular dystrophy; Genetic enhancement; Medicine; Duchenne muscular dystrophy; Bioinformatics; Disease; Skeletal muscle; Heart disease; Modalities; Cardiology; Heart failure; Gene; Internal medicine; Genetics; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.2146530999943036,"gpt":0.3527091930057725,"spread":0.1380560930114689,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000173092,0.0004047295,0.0008700121,0.00005767896,0.0001388032,0.000009588567,0.0004620196,0.000135199,0.000009946198],"category_scores_gemma":[0.000007196968,0.0002186467,0.001013971,0.0001010233,0.0001262218,0.000003041198,0.00006869665,0.00007852185,0.000002161809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000314448,"about_ca_system_score_gemma":0.0003133167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001278787,"about_ca_topic_score_gemma":0.000001386094,"domain_scores_codex":[0.9985,0.0002226157,0.0004807874,0.0003892774,0.0001234326,0.0002838678],"domain_scores_gemma":[0.9986448,0.00003417976,0.0003245631,0.0008604085,0.00008376555,0.00005227401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000151131,0.0002069585,0.00002666784,0.001040748,0.0005245539,2.070135e-7,0.0002477876,0.0001084154,0.01288339,0.00001501195,0.0002910041,0.9845041],"study_design_scores_gemma":[0.0007135252,0.0008553625,0.00007648378,0.0006328514,0.0001182525,0.000006602423,0.00006264597,3.749345e-7,0.02562848,0.00004134584,0.9716062,0.0002578677],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07396419,0.9232363,0.0001122839,0.0001390372,0.0007034324,0.001623275,0.000204656,0.000005682768,0.0000111759],"genre_scores_gemma":[0.006371065,0.9914829,0.00006928689,0.00009013071,0.000498034,0.001186926,0.0002113893,0.00005623064,0.00003411102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9842463,"threshold_uncertainty_score":0.8916153,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}