{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":151,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":151,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"94f509111200","filters":{"venue":"Current Medicinal Chemistry"}},"results":[{"id":"W2066404978","doi":"10.2174/092986711795328382","title":"Quinoline as a Privileged Scaffold in Cancer Drug Discovery","year":2011,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":571,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Sudbury Regional Hospital","funders":"","keywords":"Quinoline; Chemistry; Drug discovery; Context (archaeology); Ring (chemistry); Combinatorial chemistry; Pyridine; Structure–activity relationship; Small molecule; Stereochemistry; Biochemistry; Biology; In vitro; Organic chemistry","authors":[{"name":"V. Raja Solomon","is_ca":true},{"name":"H. Lee","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0983328954203513,"gpt":0.3674668712724432,"spread":0.2691339758520919,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003335868,0.0005137236,0.0006170162,0.001262841,0.00025967,0.0005538091,0.0006218955,0.0005218519,0.002195706],"category_scores_gemma":[0.0001791226,0.00024253,0.0002059473,0.001277981,0.0004092812,0.001020163,0.0005377951,0.0007856641,0.001544184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005621444,"about_ca_system_score_gemma":0.0005329169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005803868,"about_ca_topic_score_gemma":0.001101272,"domain_scores_codex":[0.9999036,0.0000186379,0.000008262272,0.00002171751,0.00003140897,0.00001641127],"domain_scores_gemma":[0.9999421,0.00001951287,0.00001002229,0.000003583973,0.00001537833,0.000009476829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001097958,0.0001477571,0.0002466498,0.01217802,0.00005794198,0.0007941895,0.000179554,0.001919776,0.03447018,0.02568327,0.01632108,0.9078917],"study_design_scores_gemma":[0.00001973459,0.000159274,0.0005953895,0.000706015,0.00002991178,0.001469898,0.00004769575,0.0003554089,0.005322117,0.003700881,0.9875744,0.00001924122],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001480626,0.9926319,0.001050436,0.0002364522,0.0001462304,0.00001278636,0.00003419126,0.00002348986,0.00438393],"genre_scores_gemma":[0.009724883,0.9865875,0.001167802,0.0001626427,0.0001712266,0.00001480505,0.00005702006,0.000003464266,0.002110675],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002195706,"threshold_uncertainty_score":0.007345378,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2130778084","doi":"10.2174/0929867003375335","title":"Propofol in Anesthesia. Mechanism of Action, Structure-Activity Relationships, and Drug Delivery","year":2000,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Anesthesia and Sedative Agents","field":"Medicine","cited_by":421,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre hospitalier de l'Université Laval; Wilfrid Laurier University","funders":"","keywords":"Propofol; Pharmacology; GABAA receptor; Anesthetic; Anticonvulsant; Chemistry; Mechanism of action; Pharmacokinetics; Medicine; Anesthesia; Receptor; Epilepsy; Biochemistry","authors":[{"name":"Giuseppe Trapani","is_ca":false},{"name":"Cosimo Altomare","is_ca":false},{"name":"Enrico Sanna","is_ca":false},{"name":"G. Biggio","is_ca":false},{"name":"Gaetano Liso","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0867928357879052,"gpt":0.3508352691007782,"spread":0.264042433312873,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003204482,0.0009186552,0.0006778907,0.0006606225,0.0002584957,0.0009849441,0.0006702263,0.0009708909,0.00478573],"category_scores_gemma":[0.0001872112,0.0002648252,0.0003905663,0.0007520008,0.0003567585,0.001051027,0.0005086581,0.001744385,0.00300074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007764291,"about_ca_system_score_gemma":0.0005062539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008541364,"about_ca_topic_score_gemma":0.000829765,"domain_scores_codex":[0.9997937,0.00004238288,0.00001596122,0.00003409281,0.00007588646,0.00003796845],"domain_scores_gemma":[0.9999192,0.00001572247,0.00003026374,0.000003628552,0.00001969697,0.00001149019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003595917,0.0004874499,0.0006125537,0.01265072,0.00009573983,0.001250794,0.0001720737,0.003093926,0.1085944,0.04055256,0.02581446,0.8063157],"study_design_scores_gemma":[0.0001012051,0.002720308,0.003818211,0.001365178,0.0001620436,0.004544637,0.0001315101,0.001978668,0.02373794,0.01201976,0.9493479,0.00007269799],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004870609,0.9777192,0.002058482,0.001241248,0.0004204863,0.00006116939,0.000157408,0.00005135578,0.01342007],"genre_scores_gemma":[0.04300829,0.9407457,0.002253865,0.0009768649,0.0006662178,0.00009359419,0.0002360282,0.00001211213,0.01200724],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00478573,"threshold_uncertainty_score":0.01600981,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2138475390","doi":"10.2174/092986708783497337","title":"Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging","year":2008,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Neurological Disorders and Treatments","field":"Neuroscience","cited_by":388,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; Memorial University of Newfoundland; University of Prince Edward Island","funders":"","keywords":"Reactive oxygen species; Reactive nitrogen species; Oxidative stress; Chemistry; Antioxidant; Superoxide dismutase; Free-radical theory of aging; Radical; Free radical scavenger; Superoxide; Scavenger; Biochemistry; Glutathione; Pharmacology; Hydroxyl radical; Hydrogen peroxide; Enzyme; Medicine","authors":[{"name":"John T. Weber","is_ca":false},{"name":"Jennifer E. Slemmer","is_ca":true},{"name":"John J. Shacka","is_ca":false},{"name":"Marva I. Sweeney","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1139794184388631,"gpt":0.3756033388428263,"spread":0.2616239204039631,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000327628,0.0009262684,0.001111367,0.002061076,0.0003238499,0.0004985988,0.0006567714,0.0009928468,0.004073897],"category_scores_gemma":[0.0002463801,0.0001896109,0.0003002194,0.001602824,0.000396654,0.0009222029,0.0004631852,0.001126717,0.00273754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003670846,"about_ca_system_score_gemma":0.0005399889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005194509,"about_ca_topic_score_gemma":0.001486555,"domain_scores_codex":[0.99988,0.0000206756,0.00001496229,0.00002065239,0.00005052243,0.00001312151],"domain_scores_gemma":[0.9999007,0.00002959663,0.00002285422,0.000004830665,0.00002670471,0.00001528582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001012009,0.0001981481,0.0001631597,0.007132991,0.00005687149,0.0003346782,0.00008892359,0.0003168457,0.01275121,0.004267706,0.0158928,0.9586954],"study_design_scores_gemma":[0.00003984432,0.0003058385,0.001316469,0.001183686,0.00007468331,0.002079888,0.00007615238,0.0001185396,0.003582965,0.003058728,0.9881429,0.00002027959],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005763138,0.9960192,0.0005105542,0.0003079248,0.00022017,0.00001658419,0.00002331755,0.00001814619,0.002307833],"genre_scores_gemma":[0.002770517,0.9932925,0.00109797,0.0002145157,0.0002054425,0.00002383224,0.00004407943,0.000003337916,0.002347867],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004073897,"threshold_uncertainty_score":0.01362854,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2523087930","doi":"10.2174/0929867323666160909153707","title":"The Antidiabetic Potential of Quercetin: Underlying Mechanisms","year":2016,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Phytochemicals and Antioxidant Activities","field":"Medicine","cited_by":297,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Quercetin; Insulin resistance; Flavonoid; Pharmacology; Glucose homeostasis; Glucose uptake; Diabetes mellitus; Bioavailability; Insulin; AMPK; Adipose tissue; Medicine; Antioxidant; Endocrinology; Biology; Biochemistry","authors":[{"name":"Pierre S. Haddad","is_ca":true},{"name":"Hoda M. Eid","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06303774043191532,"gpt":0.3718713099818615,"spread":0.3088335695499461,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002651739,0.000676672,0.0007442037,0.001477558,0.0002741032,0.0007844113,0.0006877483,0.0007952463,0.002478926],"category_scores_gemma":[0.0002094217,0.0001888639,0.0004063146,0.00123159,0.0004611959,0.001098729,0.0005840286,0.00102626,0.000765619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004485543,"about_ca_system_score_gemma":0.0005863366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008381491,"about_ca_topic_score_gemma":0.001418069,"domain_scores_codex":[0.9999056,0.00001432274,0.000011295,0.00002017222,0.00003556185,0.00001309963],"domain_scores_gemma":[0.9999422,0.00001469429,0.00001463451,0.000002053668,0.00001798484,0.000008388787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009513625,0.0001267807,0.0003880165,0.0156978,0.00009759688,0.0005702399,0.0001343954,0.0004143118,0.014252,0.008819954,0.009864794,0.9495389],"study_design_scores_gemma":[0.00005682899,0.0003197989,0.004714664,0.003997237,0.0002171127,0.004058158,0.0001865755,0.0003905924,0.004044506,0.01125101,0.9707218,0.00004183563],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006053034,0.9974597,0.0002571146,0.0004939506,0.00008456517,0.000005957321,0.00001797388,0.000007333411,0.001068147],"genre_scores_gemma":[0.003346894,0.9958119,0.0001954325,0.0001555291,0.00009522304,0.000005596248,0.00001815501,6.932256e-7,0.000370532],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002478926,"threshold_uncertainty_score":0.008292854,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2117965089","doi":"10.2174/0929867003375371","title":"Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships","year":2000,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Wilfrid Laurier University; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Antiandrogens; Flutamide; Prostate cancer; Antiandrogen; Androgen receptor; Internal medicine; Endocrinology; Androgen; Testosterone (patch); Dihydrotestosterone; Medicine; Enzalutamide; Chemistry; Hormone; Cancer","authors":[{"name":"Shankar Singh","is_ca":true},{"name":"Sylvain Gauthier","is_ca":false},{"name":"Fernand Labrie","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1085032400324328,"gpt":0.3998477820769277,"spread":0.2913445420444949,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005529512,0.0005997976,0.0005215744,0.000568334,0.0002107894,0.0006865357,0.0004392034,0.0005332172,0.01363994],"category_scores_gemma":[0.0004607971,0.0002474008,0.0005942683,0.0004703175,0.0001475128,0.0002858565,0.0001915546,0.0006434654,0.004026674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003306514,"about_ca_system_score_gemma":0.0002799869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000296149,"about_ca_topic_score_gemma":0.001215209,"domain_scores_codex":[0.999625,0.0001023564,0.00003135357,0.00004779175,0.0001429534,0.00005048836],"domain_scores_gemma":[0.999741,0.00007255374,0.00007856244,0.00001469536,0.00005837468,0.00003477378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00238328,0.002314621,0.00517579,0.003597821,0.0004751764,0.0008880335,0.0001092968,0.002144076,0.4488078,0.00582192,0.01609387,0.5121883],"study_design_scores_gemma":[0.002039364,0.04054198,0.05475941,0.0004964992,0.0007887525,0.01025196,0.0001616614,0.002136936,0.1839095,0.003476454,0.7013509,0.00008658344],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.235524,0.5762045,0.008830126,0.003501615,0.001359524,0.00144546,0.004610827,0.0007575638,0.1677663],"genre_scores_gemma":[0.7006053,0.2240003,0.006599005,0.003818581,0.001486817,0.0005832558,0.003434959,0.00004937201,0.05942253],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01363994,"threshold_uncertainty_score":0.0456301,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2112698509","doi":"10.2174/092986707780830989","title":"The Road to Advanced Glycation End Products: A Mechanistic Perspective","year":2007,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":215,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Biotechnology Research Institute; National Research Council Canada","funders":"Diabetes Action Research and Education Foundation","keywords":"Glycation; Amadori rearrangement; Chemistry; Pentosidine; Biochemistry; Lysine; Advanced glycation end-product; Maillard reaction; Reactive intermediate; Amino acid; Receptor","authors":[{"name":"S.-J. Cho","is_ca":false},{"name":"Gheorghe Roman","is_ca":false},{"name":"Faustinus K. Yeboah","is_ca":false},{"name":"Y. Konishi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05533150867112586,"gpt":0.426999099856496,"spread":0.3716675911853701,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001042308,0.001396196,0.001756253,0.001941004,0.000457158,0.001519362,0.001469289,0.002314125,0.00378797],"category_scores_gemma":[0.00063951,0.0004460648,0.0004786083,0.00257893,0.001190486,0.00467175,0.0009919419,0.003807575,0.003860553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001065125,"about_ca_system_score_gemma":0.00124969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006625749,"about_ca_topic_score_gemma":0.001032195,"domain_scores_codex":[0.9997608,0.00004596265,0.00002522158,0.00003990742,0.00009690871,0.00003120726],"domain_scores_gemma":[0.9996552,0.0001307918,0.00004034136,0.00001832089,0.0001025126,0.00005274347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001648277,0.0002319969,0.0001479409,0.01671978,0.0000829916,0.0006936493,0.0001686972,0.001020704,0.008086413,0.03363784,0.06368048,0.8753648],"study_design_scores_gemma":[0.00001340714,0.0001241773,0.0001766693,0.001254518,0.00002295524,0.0006940708,0.00006483588,0.0001018253,0.0007562779,0.006219255,0.9905566,0.00001535525],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001030498,0.9966612,0.0003378989,0.0009278038,0.0006506655,0.000004471587,0.00000811933,0.00001133059,0.001295532],"genre_scores_gemma":[0.0005154252,0.9974533,0.0004002077,0.0004017908,0.0003874292,0.000005883292,0.00001010271,0.000001419845,0.0008245438],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00378797,"threshold_uncertainty_score":0.01267201,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1985196300","doi":"10.2174/092986709787549299","title":"Polymorphism and Crystallization of Active Pharmaceutical Ingredients (APIs)","year":2009,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Crystallization and Solubility Studies","field":"Materials Science","cited_by":214,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Active ingredient; Crystallization; Polymorphism (computer science); Pharmaceutical technology; Chemistry; Computational biology; Combinatorial chemistry; Pharmacology; Medicine; Chromatography; Biology; Organic chemistry; Biochemistry","authors":[{"name":"Jie Lü","is_ca":true},{"name":"Sohrab Rohani","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0809852827080931,"gpt":0.3967175121136604,"spread":0.3157322294055673,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006128291,0.000392507,0.0006736192,0.0009008547,0.0002194385,0.0005297748,0.0005647716,0.0004096727,0.001009583],"category_scores_gemma":[0.0005314124,0.0002759789,0.0004015297,0.001219947,0.0004790825,0.000755775,0.0004379103,0.0006641023,0.0009888767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004307568,"about_ca_system_score_gemma":0.000523584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001004273,"about_ca_topic_score_gemma":0.0009977729,"domain_scores_codex":[0.9996077,0.00006568753,0.00003518436,0.00008785874,0.0001743711,0.00002926281],"domain_scores_gemma":[0.9998727,0.00005026361,0.00003093856,0.00001158859,0.00002901161,0.000005532739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001628018,0.0001464965,0.001142038,0.01258438,0.00006688332,0.0005546864,0.0002777821,0.002028872,0.1918577,0.01745693,0.005469942,0.7682515],"study_design_scores_gemma":[0.00004051669,0.0003976643,0.004798667,0.0008685167,0.00009437968,0.003697227,0.0001464204,0.002006502,0.34726,0.004714034,0.6359309,0.00004507851],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02043312,0.9577684,0.009571698,0.0003668194,0.0001891147,0.00007483482,0.0001321452,0.00006455627,0.01139935],"genre_scores_gemma":[0.0833087,0.8989349,0.009247365,0.0001962046,0.0001700236,0.0001005663,0.0002475327,0.00002746233,0.007767333],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001009583,"threshold_uncertainty_score":0.003377378,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2107215997","doi":"10.2174/092986711795933740","title":"Aluminum Vaccine Adjuvants: Are they Safe?","year":2011,"lang":"en","type":"article","venue":"Current Medicinal Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":209,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"U.S. Food and Drug Administration; Fox Family Foundation","keywords":"Adjuvant; Adverse effect; Medicine; Intensive care medicine; Vaccine adjuvant; Scarcity; Immunology; Pharmacology","authors":[{"name":"Lucija Tomljenovic","is_ca":true},{"name":"C. Shaw","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03072968108542249,"gpt":0.2648487694297985,"spread":0.234119088344376,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004044855,0.0004691144,0.001163576,0.0005005751,0.0005078377,0.002097957,0.0006593484,0.003843732,0.005658041],"category_scores_gemma":[0.006954651,0.0003107438,0.0004445789,0.0002792804,0.003606911,0.004354052,0.0007264304,0.002064355,0.002828265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00064809,"about_ca_system_score_gemma":0.001082526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000329762,"about_ca_topic_score_gemma":0.000527269,"domain_scores_codex":[0.9984478,0.0005116297,0.0001117457,0.0001448274,0.0006480608,0.0001359379],"domain_scores_gemma":[0.9972242,0.001207497,0.0007255066,0.0001847504,0.000443668,0.0002143859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002996515,0.0005498159,0.007136129,0.006764332,0.0003719581,0.002347586,0.001329065,0.001182448,0.1515928,0.1277552,0.04857972,0.6493946],"study_design_scores_gemma":[0.0004644186,0.003836686,0.002926618,0.002291801,0.0004006254,0.004591216,0.002476815,0.0008238523,0.09719811,0.1781152,0.7067442,0.0001304713],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07670857,0.6606563,0.02879108,0.1957737,0.005809052,0.0001522531,0.0004263819,0.0003963937,0.03128638],"genre_scores_gemma":[0.5977406,0.2984983,0.01572043,0.05583796,0.006878714,0.0003182516,0.0003837263,0.0002332474,0.02438872],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005658041,"threshold_uncertainty_score":0.02139151,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2113999268","doi":"10.2174/092986712800784702","title":"Drug-Loaded Nanocarriers: Passive Targeting and Crossing of Biological Barriers","year":2012,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":198,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Nanocarriers; Transcytosis; Drug delivery; Bioavailability; Pharmacology; Drug; Systemic administration; Targeted drug delivery; Chemistry; Drug carrier; Nanotechnology; Medicine; In vivo; Endocytosis; Biology; Materials science; Cell; Biochemistry","authors":[{"name":"Jean‐Michel Rabanel","is_ca":true},{"name":"Valéry Aoun","is_ca":false},{"name":"Igor Elkin","is_ca":true},{"name":"M. Mokhtar","is_ca":false},{"name":"P. Hildgen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05023832251794057,"gpt":0.3232243465473588,"spread":0.2729860240294182,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004548765,0.0005764699,0.0006964563,0.0004309455,0.0002148052,0.0008879467,0.0004149102,0.0009061404,0.0008910317],"category_scores_gemma":[0.0003235401,0.0002368856,0.0002751469,0.0003048803,0.0005483337,0.001146056,0.0005080761,0.0008989089,0.0008181468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006253064,"about_ca_system_score_gemma":0.000413938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004868797,"about_ca_topic_score_gemma":0.0004395644,"domain_scores_codex":[0.9997264,0.00005267126,0.00002040269,0.0000581234,0.0001010792,0.00004136853],"domain_scores_gemma":[0.9998876,0.00004048368,0.0000303196,0.000006331717,0.00002331719,0.00001189653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000150527,0.00008657335,0.0002645084,0.005695383,0.00005440159,0.0006379843,0.0002622733,0.001602519,0.7446299,0.03182242,0.004569973,0.2102236],"study_design_scores_gemma":[0.00003293355,0.0005484062,0.0009126872,0.0004190738,0.00008391033,0.002759401,0.00009122368,0.003878833,0.6384251,0.005696512,0.3470976,0.0000542215],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06213541,0.7869429,0.1152197,0.003172835,0.0008804902,0.0003554023,0.0002328701,0.000622699,0.03043783],"genre_scores_gemma":[0.305608,0.6057245,0.05152509,0.002282095,0.0006117136,0.0004194312,0.000338265,0.0001281849,0.03336272],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0009061404,"threshold_uncertainty_score":0.004536986,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2726037479","doi":"10.2174/0929867324666170705143308","title":"Applications of Cellulose-based Materials in Sustained Drug Delivery Systems","year":2018,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Advanced Cellulose Research Studies","field":"Materials Science","cited_by":182,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lakehead University; University of New Brunswick","funders":"","keywords":"Cellulose; Drug delivery; Solubility; Drug; Chemistry; Drug carrier; Nanotechnology; Materials science; Combinatorial chemistry; Organic chemistry; Pharmacology; Medicine","authors":[{"name":"Bo Sun","is_ca":false},{"name":"M. Zhang","is_ca":false},{"name":"Jing Shen","is_ca":true},{"name":"Zhibin He","is_ca":true},{"name":"Pedram Fatehi","is_ca":true},{"name":"Yonghao Ni","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04110812690774133,"gpt":0.3594360101725069,"spread":0.3183278832647655,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003677247,0.0007075378,0.0006608609,0.001984619,0.000283348,0.000761361,0.0004225125,0.0008255843,0.002308246],"category_scores_gemma":[0.0002415614,0.0002551161,0.0003870555,0.001704096,0.0003974989,0.001006114,0.0005303387,0.00126535,0.001474871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005086319,"about_ca_system_score_gemma":0.0005254383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006613772,"about_ca_topic_score_gemma":0.0007601274,"domain_scores_codex":[0.9997986,0.00002378265,0.00002081158,0.00003653762,0.00009607305,0.00002413845],"domain_scores_gemma":[0.9998999,0.0000363736,0.00002134679,0.000005033954,0.00002561937,0.00001181105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006365676,0.0001858806,0.0002029754,0.02014847,0.00007508937,0.0009303147,0.0001895048,0.001153153,0.1080392,0.01831851,0.01097746,0.8397159],"study_design_scores_gemma":[0.00001327263,0.0001587464,0.000712993,0.00155747,0.00005574137,0.002376421,0.00006584458,0.0003436962,0.03768692,0.002570634,0.9544256,0.00003259528],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001518483,0.990404,0.001425552,0.0002185368,0.0002621119,0.00001928055,0.00003281425,0.00002183533,0.006097417],"genre_scores_gemma":[0.008935565,0.9859358,0.0019099,0.0001921427,0.0002035574,0.00002160725,0.00003668654,0.000004232018,0.002760417],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002308246,"threshold_uncertainty_score":0.007721841,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2168391786","doi":"10.2174/092986706779026174","title":"Targeting the EGFR Pathway for Cancer Therapy","year":2006,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance; Strong; CancerCare Manitoba Foundation; Manitoba Medical Service Foundation; Manitoba Health Research Council","keywords":"Cetuximab; Medicine; Gefitinib; Panitumumab; Pertuzumab; Lapatinib; Erlotinib; Amphiregulin; Epidermal growth factor receptor; Lung cancer; Targeted therapy; Trastuzumab; Cancer; Cancer research; Breast cancer; Epidermal growth factor; Oncology; Internal medicine; Colorectal cancer; Receptor","authors":[{"name":"James C. Johnston","is_ca":false},{"name":"Sri Navaratnam","is_ca":false},{"name":"Marshall Pitz","is_ca":false},{"name":"Jerry Maniate","is_ca":true},{"name":"Emilia Wiecheć","is_ca":false},{"name":"Heinrich Baust","is_ca":false},{"name":"Joel Gingerich","is_ca":false},{"name":"Georgios Skliris","is_ca":false},{"name":"Leigh C. Murphy","is_ca":false},{"name":"Marek Łoś","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1949928734727937,"gpt":0.4903576461793562,"spread":0.2953647727065626,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002544507,0.0005900143,0.0005492595,0.0008331708,0.0001869427,0.0007720212,0.000512422,0.001068394,0.008880743],"category_scores_gemma":[0.0002147051,0.0001286633,0.0004191024,0.0005445321,0.0003208163,0.0008786254,0.0006349576,0.002165714,0.004729549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007762468,"about_ca_system_score_gemma":0.0004734692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004303576,"about_ca_topic_score_gemma":0.0008571763,"domain_scores_codex":[0.9998173,0.00003184934,0.00001254528,0.00003836411,0.00007251107,0.00002749321],"domain_scores_gemma":[0.9999396,0.00001745716,0.00001148701,0.000004394106,0.00001765782,0.000009508291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001222726,0.0001197011,0.0001596224,0.005217055,0.00007414874,0.0003877508,0.00007416974,0.0008249076,0.02103741,0.01764371,0.0730963,0.8812431],"study_design_scores_gemma":[0.00001605017,0.0001049042,0.0002505922,0.0006277665,0.00003341477,0.0009995106,0.0000163089,0.0002002987,0.002266098,0.003115713,0.9923584,0.00001101215],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007789789,0.9826396,0.001600012,0.002013846,0.0009660454,0.00001987307,0.00007343874,0.00006094664,0.01184734],"genre_scores_gemma":[0.0110095,0.9648997,0.001618618,0.001993156,0.001145592,0.00003800276,0.0001902463,0.00001718372,0.01908818],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008880743,"threshold_uncertainty_score":0.02970904,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2412673684","doi":"10.2174/0929867033368222","title":"Inhibitors of 17β-Hydroxysteroid Dehydrogenases","year":2003,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":172,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"","keywords":"Hydroxysteroid Dehydrogenases; Intracrine; NAD+ kinase; Isozyme; Enzyme; Steroid; Biochemistry; Cofactor; Hydroxysteroid; Biology; Gene isoform; Estrogen; Hormone; Chemistry; Receptor; Gene; Endocrinology; Dehydrogenase","authors":[{"name":"Donald Poirier","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03370452801413893,"gpt":0.339500232107973,"spread":0.3057957040938341,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003165087,0.001061435,0.0006813409,0.0004869992,0.0002382821,0.0006629005,0.0006894538,0.0005851664,0.009985526],"category_scores_gemma":[0.0003335318,0.0002632431,0.0006517001,0.0005131114,0.0002564706,0.0002736755,0.0004120894,0.001272805,0.005990154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005319268,"about_ca_system_score_gemma":0.0005230772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009701761,"about_ca_topic_score_gemma":0.001257423,"domain_scores_codex":[0.9995763,0.00006448297,0.00003891004,0.00008054631,0.0001498139,0.00008989517],"domain_scores_gemma":[0.999892,0.00002116499,0.00002240903,0.0000121069,0.0000316772,0.00002066091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002248521,0.0009508212,0.001307322,0.00259129,0.0002624126,0.0007217863,0.00009367191,0.001320333,0.6490092,0.00853742,0.02134646,0.3116106],"study_design_scores_gemma":[0.0005955984,0.001940584,0.003125581,0.000239735,0.0001808328,0.001715736,0.00005605354,0.001503308,0.4136965,0.001388762,0.5755118,0.00004543391],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1658165,0.6267188,0.03978002,0.004784806,0.005347915,0.001365738,0.009445444,0.002354162,0.1443867],"genre_scores_gemma":[0.5295886,0.2929225,0.03050135,0.002742738,0.0007827796,0.001475784,0.01046669,0.0002307284,0.1312888],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009985526,"threshold_uncertainty_score":0.03340495,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2153525593","doi":"10.2174/0929867053363351","title":"Biologically Active Quassinoids and Their Chemistry: Potential Leads for Drug Design","year":2005,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Phytochemical compounds biological activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":167,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Simaroubaceae; Chemistry; Terpene; Biological activity; Stereochemistry; Broad spectrum; Traditional medicine; Combinatorial chemistry; Biochemistry; In vitro; Medicine","authors":[{"name":"Zhenghong Guo","is_ca":false},{"name":"Suryanarayana Vangapandu","is_ca":true},{"name":"Robert D. Sindelar","is_ca":true},{"name":"Larry Walker","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05658711015692831,"gpt":0.3357921422237512,"spread":0.2792050320668229,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003832493,0.0007592259,0.001178301,0.001327654,0.0002865848,0.0009889421,0.0009470482,0.0009706291,0.004730966],"category_scores_gemma":[0.0002648404,0.0003026977,0.0003341448,0.001396833,0.0005577006,0.001666486,0.0005605379,0.001442812,0.003616962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006409853,"about_ca_system_score_gemma":0.0005236646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004875526,"about_ca_topic_score_gemma":0.001031031,"domain_scores_codex":[0.9999079,0.00001782558,0.000009591193,0.00001806814,0.00003330507,0.00001343981],"domain_scores_gemma":[0.9999031,0.00002736405,0.00001679393,0.000005191929,0.00002949771,0.00001804864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001463917,0.0001884619,0.0001834497,0.01092847,0.0000676795,0.0006722268,0.0001607257,0.00178853,0.02319988,0.0213503,0.03188498,0.909429],"study_design_scores_gemma":[0.0000645217,0.0002255885,0.0003669325,0.001079345,0.00004785207,0.001091932,0.00009797327,0.0003890604,0.00286482,0.008968046,0.9847773,0.00002647606],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005782892,0.993714,0.001495172,0.0005024745,0.000334316,0.0000184929,0.00003540524,0.00003118681,0.003290617],"genre_scores_gemma":[0.003464794,0.9926617,0.001412927,0.0002752451,0.0002603444,0.00002290364,0.00007375125,0.000003314806,0.001825003],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004730966,"threshold_uncertainty_score":0.01582664,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2112949474","doi":"10.2174/092986712802884204","title":"1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets","year":2012,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":144,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Scaffold; Chemistry; Dihydropyridine; Action (physics); Calcium; Engineering; Organic chemistry; Biomedical engineering; Physics","authors":[{"name":"Emanuele Carosati","is_ca":false},{"name":"Pierfranco Ioan","is_ca":false},{"name":"Matteo Micucci","is_ca":false},{"name":"Fabio Broccatelli","is_ca":false},{"name":"Gabriele Cruciani","is_ca":false},{"name":"B. S. Zhorov","is_ca":false},{"name":"Alberto Chiarini","is_ca":false},{"name":"Roberta Budriesi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07181555793529072,"gpt":0.3441136671950139,"spread":0.2722981092597231,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004799922,0.0006340825,0.0008484906,0.001259518,0.0002848735,0.0009398879,0.0006112442,0.0009478673,0.004363792],"category_scores_gemma":[0.0003907109,0.0002872934,0.0002762635,0.001894885,0.0007718149,0.001951531,0.0005953103,0.001944351,0.002880202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007701545,"about_ca_system_score_gemma":0.0006550483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005968764,"about_ca_topic_score_gemma":0.001056472,"domain_scores_codex":[0.9998753,0.00002195841,0.00001291998,0.00002760979,0.00004400384,0.00001824003],"domain_scores_gemma":[0.9998602,0.00005756049,0.00001904132,0.000007831284,0.00003575789,0.00001963808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007947525,0.0001306602,0.0001077199,0.009958905,0.0000385987,0.0003114655,0.0001141333,0.0006551692,0.006500097,0.01542176,0.05550746,0.9111745],"study_design_scores_gemma":[0.00001207323,0.00008700202,0.0003545458,0.0009275548,0.0000204152,0.0008420596,0.00005214879,0.0001026282,0.0008128771,0.003447004,0.9933292,0.00001259187],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002199201,0.9965298,0.0002472067,0.0005612522,0.0003930591,0.000004508403,0.0000155288,0.00001162956,0.002017168],"genre_scores_gemma":[0.00168542,0.9954996,0.0003065921,0.0004167998,0.0004112798,0.000006595325,0.00001955359,0.000002546129,0.001651545],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004363792,"threshold_uncertainty_score":0.01459837,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2153483615","doi":"10.2174/0929867024606704","title":"Thiol-Dependent Enzymes and Their Inhibitors: A Review","year":2002,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":125,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Proteases; Cysteine protease; Cysteine; Cathepsin; Thiol; Chemistry; Enzyme; Cysteine Proteinase Inhibitors; Biochemistry; Protease; Peptidomimetic; Rhinovirus; Pharmacology; Caspase; Medicine; Immunology; Programmed cell death; Virus; Apoptosis","authors":[{"name":"Régis Leung-Toung","is_ca":true},{"name":"Wanren Li","is_ca":false},{"name":"Tim F. Tam","is_ca":false},{"name":"Khashayar Kaarimian","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08353658814692388,"gpt":0.3249277320088695,"spread":0.2413911438619456,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003878876,0.001192593,0.001206127,0.002403865,0.0003569312,0.000999277,0.0008542842,0.0009864968,0.004845391],"category_scores_gemma":[0.0004144905,0.0004036583,0.0004500682,0.002713025,0.0003549693,0.001377683,0.0005982364,0.001590636,0.003882091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004954413,"about_ca_system_score_gemma":0.0007680243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005942624,"about_ca_topic_score_gemma":0.0009485887,"domain_scores_codex":[0.9997838,0.00002854156,0.00002785887,0.0000430712,0.00008905015,0.0000276548],"domain_scores_gemma":[0.9998282,0.00005955052,0.00003513484,0.000008638934,0.00004546925,0.00002297011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001238786,0.0002438971,0.0001280183,0.01820852,0.0000799076,0.0003168378,0.00006808926,0.0007508096,0.00829514,0.00446852,0.03786309,0.9294532],"study_design_scores_gemma":[0.00001672598,0.0001709183,0.000317399,0.0009677585,0.00006915664,0.0009034736,0.00002201661,0.0001446289,0.001909105,0.0008751011,0.9945821,0.00002157626],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003578513,0.9965551,0.0005016776,0.0001598029,0.0003793421,0.00001884215,0.00005946225,0.00002381483,0.001943994],"genre_scores_gemma":[0.001751167,0.9953303,0.0006560855,0.0002126222,0.0003351882,0.00002737121,0.0001121783,0.000004342364,0.001570684],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004845391,"threshold_uncertainty_score":0.01620942,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2063479802","doi":"10.2174/0929867033457593","title":"Iron Chelator Research: Past, Present, and Future","year":2003,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Deferiprone; Deferasirox; Deferoxamine; Cardiotoxicity; Chelation therapy; Medicine; Pharmacology; Thalassemia; Toxicity; Clinical trial; Hereditary hemochromatosis; Beta thalassemia; Anthracycline; Hemochromatosis; Cancer; Internal medicine","authors":[{"name":"Tim F. Tam","is_ca":true},{"name":"Régis Leung-Toung","is_ca":false},{"name":"Wanren Li","is_ca":false},{"name":"Yingsheng Wang","is_ca":false},{"name":"Khashayar Karimian","is_ca":false},{"name":"Michael Spino","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0955278868963563,"gpt":0.4095493228791964,"spread":0.3140214359828402,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009872575,0.000877743,0.001334836,0.002104999,0.0004584409,0.001492886,0.0008912105,0.001386125,0.004571438],"category_scores_gemma":[0.0006341639,0.0002976237,0.0004325119,0.003406552,0.0007753533,0.00273601,0.0006026065,0.001506879,0.003217073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008544953,"about_ca_system_score_gemma":0.001344906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001048308,"about_ca_topic_score_gemma":0.00237336,"domain_scores_codex":[0.9997953,0.00003895098,0.00002908021,0.00003967621,0.00007348736,0.00002356904],"domain_scores_gemma":[0.9996045,0.000150782,0.00005603984,0.00002237795,0.0001073738,0.00005894612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001046208,0.0001513112,0.0001862568,0.007691024,0.00003382251,0.0002293607,0.00008977871,0.000255029,0.002360869,0.00321438,0.02172476,0.9639589],"study_design_scores_gemma":[0.00003384681,0.0002393172,0.001001407,0.002788538,0.00006206897,0.001553974,0.0001431379,0.0001637809,0.0007513705,0.004131055,0.9891126,0.00001897378],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001632457,0.997709,0.0001321443,0.0004686576,0.0001843738,0.000003184679,0.000006280477,0.000007223789,0.001325798],"genre_scores_gemma":[0.0009637995,0.9969516,0.0003250983,0.0003076915,0.0002695301,0.000006224591,0.00001359794,0.000001896511,0.001160618],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004571438,"threshold_uncertainty_score":0.015293,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101578637","doi":"10.2174/092986712803414141","title":"Nonviral Approach for Targeted Nucleic Acid Delivery","year":2012,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene delivery; Nucleic acid; Transfection; Genetic enhancement; Electroporation; Cationic liposome; Gene knockdown; Oligonucleotide; DNA; Plasmid; Biology; Chemistry; Molecular biology; Biochemistry; Gene","authors":[{"name":"Mohammadamin Jafari","is_ca":true},{"name":"M. Soltani","is_ca":false},{"name":"Sheva Naahidi","is_ca":false},{"name":"D. Nedra Karunaratne","is_ca":false},{"name":"P. Chen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06277982800155697,"gpt":0.3296279748397128,"spread":0.2668481468381559,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002879608,0.0006947695,0.0006858648,0.0009842335,0.0002458641,0.0005738543,0.0006834121,0.0006361188,0.004051508],"category_scores_gemma":[0.000154247,0.0002050216,0.0003591726,0.000656774,0.0003169729,0.000644776,0.0004638128,0.0008432018,0.003288603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005259637,"about_ca_system_score_gemma":0.0005408378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003492749,"about_ca_topic_score_gemma":0.0005585353,"domain_scores_codex":[0.9997764,0.00002666834,0.00001326515,0.00004507346,0.0001169002,0.00002164053],"domain_scores_gemma":[0.9999465,0.00001673486,0.0000110232,0.000004592726,0.00001523325,0.00000598969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007938607,0.0002190476,0.0001647296,0.008247716,0.00005768436,0.0007401308,0.0001290844,0.0004523088,0.369391,0.0180978,0.009902755,0.5925184],"study_design_scores_gemma":[0.00002410386,0.0003602027,0.0006171218,0.0005018027,0.00006159905,0.003114201,0.00005047039,0.0005768581,0.1768874,0.002726627,0.8150455,0.00003409312],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009497766,0.9196506,0.03839897,0.0004178547,0.001252847,0.0002516908,0.0001968172,0.0002372186,0.03009622],"genre_scores_gemma":[0.05801143,0.8743194,0.02263327,0.0008696818,0.0003465973,0.0003504762,0.0005421479,0.00006189412,0.04286515],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004051508,"threshold_uncertainty_score":0.01355362,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2092787687","doi":"10.2174/092986710790820615","title":"Click-Chemistry Reactions in Radiopharmaceutical Chemistry: Fast & Easy Introduction of Radiolabels into Biomolecules for In Vivo Imaging","year":2010,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":112,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Bioconjugation; Chemistry; Click chemistry; Biomolecule; Combinatorial chemistry; In vivo; Radiochemistry; Biochemistry","authors":[{"name":"Carmen Wängler","is_ca":true},{"name":"Ralf Schirrmacher","is_ca":true},{"name":"Peter Bartenstein","is_ca":false},{"name":"Björn Wängler","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04771563166910767,"gpt":0.3954184207556827,"spread":0.347702789086575,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001696702,0.001875775,0.001008021,0.001342339,0.0005866575,0.001567623,0.001055808,0.002120801,0.004878995],"category_scores_gemma":[0.0008138422,0.0007980628,0.0008377878,0.00212071,0.001831725,0.002957592,0.001612876,0.003126199,0.006444673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008262001,"about_ca_system_score_gemma":0.0004094092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002211069,"about_ca_topic_score_gemma":0.0001613957,"domain_scores_codex":[0.9984277,0.0003430637,0.0001558589,0.0003576168,0.0005432124,0.0001726254],"domain_scores_gemma":[0.9996144,0.0001176455,0.0001010054,0.00005086857,0.00006794165,0.00004818138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003574877,0.0003367501,0.0003868669,0.005129855,0.0001036316,0.001358128,0.0005549015,0.002183539,0.5179565,0.1820004,0.02124237,0.2683896],"study_design_scores_gemma":[0.00004813735,0.0006083376,0.0003815981,0.0002181402,0.00005267845,0.002988572,0.00004464077,0.001605712,0.5608191,0.01178015,0.4213178,0.0001350745],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.0325983,0.3227128,0.5767006,0.002692206,0.005354797,0.0007753248,0.001090193,0.003517908,0.05455783],"genre_scores_gemma":[0.3046672,0.3160448,0.2767485,0.00420766,0.003306995,0.001624409,0.002983568,0.001185542,0.08923125],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.004878995,"threshold_uncertainty_score":0.0163219,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071114368","doi":"10.2174/092986709788803222","title":"Advances in Development of Phosphatidylinositol 3-Kinase Inhibitors","year":2009,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Institut national de la recherche scientifique","keywords":"PI3K/AKT/mTOR pathway; PTEN; Phosphatidylinositol; Protein kinase B; Kinase; Tensin; Cancer research; Idelalisib; P110α; Biology; Pharmacology; Phosphorylation; Chemistry; Cell biology; Signal transduction; Immunology; Leukemia","authors":[{"name":"Dexin Kong","is_ca":false},{"name":"Takao Yamori","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02738576482826195,"gpt":0.3599386272636075,"spread":0.3325528624353455,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007443044,0.000736291,0.0008299878,0.001107268,0.0002184584,0.00104979,0.0007345221,0.0006897026,0.004175811],"category_scores_gemma":[0.0006730789,0.0002896142,0.0007244649,0.0007504595,0.0002774886,0.001132111,0.0006778183,0.002428679,0.002699604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005337534,"about_ca_system_score_gemma":0.0007022253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006497184,"about_ca_topic_score_gemma":0.001074927,"domain_scores_codex":[0.9996266,0.00005085523,0.00003155412,0.00007388398,0.0001494801,0.00006758433],"domain_scores_gemma":[0.9997877,0.00004372203,0.00003124002,0.00001257058,0.00008463154,0.00004015792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000543498,0.000584034,0.001197778,0.004244591,0.0001896328,0.0007688984,0.000118638,0.002107365,0.03187192,0.01651201,0.03930055,0.9025611],"study_design_scores_gemma":[0.0003022549,0.001038518,0.001539594,0.0005043063,0.0001917891,0.001670397,0.00004889086,0.001943349,0.01792345,0.004169248,0.9706157,0.00005249853],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01417573,0.9424425,0.01164725,0.004583798,0.001533911,0.0001698807,0.0006325716,0.0003293851,0.02448501],"genre_scores_gemma":[0.09192331,0.8796574,0.01012743,0.003439042,0.0009712755,0.0002287274,0.001630901,0.00006063101,0.01196125],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004175811,"threshold_uncertainty_score":0.01396948,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2334952028","doi":"10.2174/0929867003373292","title":"Recent Developments In Sequence Selective Minor Groove DNA Effectors","year":2000,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"DNA; Chemistry; Effector; Oligonucleotide; Stereochemistry; Binding site; Biochemistry; Combinatorial chemistry; Biology","authors":[{"name":"Sanjeev Sharma","is_ca":false},{"name":"J. William Lown","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04030999469661201,"gpt":0.3441415905158959,"spread":0.3038315958192839,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008510883,0.000601166,0.0006088681,0.0007375955,0.0001743733,0.0008819363,0.0006735987,0.0008974168,0.002899019],"category_scores_gemma":[0.0005143417,0.0003583966,0.0003302075,0.0007429849,0.0004096903,0.001339277,0.000679204,0.001277804,0.001936069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004633147,"about_ca_system_score_gemma":0.0003410543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001591184,"about_ca_topic_score_gemma":0.0001523081,"domain_scores_codex":[0.9996259,0.00005838276,0.00004066332,0.0001092691,0.0001117742,0.00005404459],"domain_scores_gemma":[0.9996516,0.0001210808,0.00005272401,0.00002694685,0.00008855238,0.00005917973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006196873,0.0004320363,0.0006181273,0.005361652,0.00006297146,0.000737714,0.0002728461,0.002184893,0.3242255,0.02652114,0.007093789,0.6318696],"study_design_scores_gemma":[0.00006359283,0.002080169,0.00112155,0.0003385812,0.0001087526,0.002700067,0.0001000715,0.002548038,0.1784492,0.004613655,0.8078175,0.00005886145],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04207218,0.8801184,0.04583036,0.00255293,0.00122763,0.0001451201,0.0002456587,0.0006213228,0.02718638],"genre_scores_gemma":[0.1387182,0.7841079,0.04315322,0.003841145,0.001798829,0.0002273518,0.001088231,0.000183844,0.02688133],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002899019,"threshold_uncertainty_score":0.009698212,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2096427004","doi":"10.2174/092986709787315568","title":"Obesity: Pathophysiology and Clinical Management","year":2009,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Pharmacology and Obesity Treatment","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Orlistat; Medicine; Sibutramine; Adiponectin; Phentermine; Appetite; Obesity; Leptin; Management of obesity; Internal medicine; Endocrinology; Dexfenfluramine; Diabetes mellitus; Bioinformatics; Fenfluramine; Insulin resistance; Weight loss; Biology","authors":[{"name":"Tatiana Gurevich-Panigrahi","is_ca":false},{"name":"Soumya Panigrahi","is_ca":false},{"name":"Emilia Wiecheć","is_ca":true},{"name":"Marek Łoś","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07920189527936355,"gpt":0.4586940153380644,"spread":0.3794921200587009,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006168769,0.001003841,0.001103385,0.00140539,0.0005916954,0.001653885,0.0008588874,0.001707333,0.00417114],"category_scores_gemma":[0.001063659,0.0002017111,0.0004925613,0.001230722,0.001006542,0.001022445,0.001236205,0.002644879,0.002216066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007452339,"about_ca_system_score_gemma":0.001367587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009894101,"about_ca_topic_score_gemma":0.000868256,"domain_scores_codex":[0.9996248,0.00009096271,0.00006075063,0.00006269669,0.0001075804,0.00005314721],"domain_scores_gemma":[0.9997051,0.00006847407,0.00006151033,0.00001660526,0.00008789395,0.00006032291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003888219,0.000271687,0.005666246,0.005412256,0.0001233417,0.005528248,0.0002507949,0.000391039,0.002057615,0.01620998,0.1037404,0.8599595],"study_design_scores_gemma":[0.0001335986,0.000441207,0.01745678,0.01046532,0.0002402496,0.06636269,0.0007105048,0.0009848168,0.0009886792,0.03467941,0.8674381,0.00009868358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002283474,0.973174,0.0023358,0.008072843,0.001961911,0.00006583304,0.0001634111,0.00009739853,0.0118454],"genre_scores_gemma":[0.03649164,0.9329356,0.004355261,0.006448837,0.009789838,0.0001681779,0.0005911065,0.00004442286,0.009175108],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00417114,"threshold_uncertainty_score":0.0139538,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2129001810","doi":"10.2174/092986707782360105","title":"Computer Simulation of Antimicrobial Peptides","year":2007,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":107,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Hungarian Scientific Research Fund; Alberta Heritage Foundation for Medical Research","keywords":"Antimicrobial peptides; Antimicrobial; Molecular dynamics; Computational biology; Chemistry; Peptide; Function (biology); Mechanism (biology); Micelle; Lipid bilayer; Nanotechnology; Combinatorial chemistry; Biochemistry; Biology; Membrane; Physics; Materials science; Computational chemistry; Organic chemistry; Cell biology","authors":[{"name":"Edit Mátyus","is_ca":false},{"name":"Christian Kandt","is_ca":false},{"name":"D. Peter Tieleman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0613111808518214,"gpt":0.352219894283032,"spread":0.2909087134312106,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002684337,0.0005456283,0.0009432525,0.0002875348,0.0005240693,0.0006230619,0.0009294031,0.001176779,0.003844256],"category_scores_gemma":[0.0009107712,0.000302304,0.0005387571,0.0005038259,0.0004868757,0.0007032778,0.0006159343,0.0008160185,0.0008647763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005783221,"about_ca_system_score_gemma":0.0007851206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002550454,"about_ca_topic_score_gemma":0.0017861,"domain_scores_codex":[0.9998599,0.00004796304,0.000007447122,0.00001939975,0.00004799548,0.00001727121],"domain_scores_gemma":[0.9997582,0.0001350015,0.00001495924,0.00001913695,0.00005138471,0.00002133546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001321914,0.00008590493,0.001104025,0.0007891049,0.0001210794,0.0002074063,0.0001033412,0.9186832,0.007094021,0.03393044,0.005590074,0.03215925],"study_design_scores_gemma":[0.000121998,0.00007767887,0.0004918358,0.0001187938,0.00003951996,0.00009894025,0.00005040479,0.922034,0.003376014,0.02223953,0.0513258,0.00002550287],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.3850703,0.06870703,0.3344208,0.005805172,0.002032249,0.0005265919,0.004074015,0.002241873,0.1971219],"genre_scores_gemma":[0.7842203,0.0354187,0.1487912,0.001476548,0.0004107655,0.001779732,0.004086119,0.0006151254,0.02320154],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003844256,"threshold_uncertainty_score":0.01286036,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2065471096","doi":"10.2174/092986711797535173","title":"1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives (Part 1): Action in Ion Channels and GPCRs","year":2011,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":104,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"DHPS; Ion channel; Scaffold; Dihydropyridine; Chemistry; Calcium channel; Voltage-dependent calcium channel; G protein-coupled receptor; Receptor; Ligand (biochemistry); Scaffold protein; Biophysics; Drug discovery; Calcium; Ligand-gated ion channel; Signal transduction; Biochemistry; Biology; Medicine","authors":[{"name":"Pierfranco Ioan","is_ca":false},{"name":"Emanuele Carosati","is_ca":false},{"name":"Matteo Micucci","is_ca":false},{"name":"Gabriele Cruciani","is_ca":false},{"name":"Fabio Broccatelli","is_ca":false},{"name":"B. S. Zhorov","is_ca":false},{"name":"Alberto Chiarini","is_ca":false},{"name":"Roberta Budriesi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09007244671368171,"gpt":0.3216648852416772,"spread":0.2315924385279955,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002269949,0.0003737637,0.0004725095,0.0006169084,0.0002268233,0.0005086707,0.0003485411,0.0004915253,0.00376689],"category_scores_gemma":[0.0001590027,0.0002004921,0.0001597219,0.0008544172,0.0003733989,0.001270525,0.0003311214,0.0009178786,0.002389146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005426213,"about_ca_system_score_gemma":0.0004475014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004708771,"about_ca_topic_score_gemma":0.001032924,"domain_scores_codex":[0.9999471,0.000009257998,0.000005933719,0.00001256474,0.00001664558,0.000008483197],"domain_scores_gemma":[0.9999492,0.00001771727,0.000009650255,0.000002843132,0.00001334009,0.000007217307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001279236,0.0001699878,0.0001558112,0.01227728,0.00003449071,0.0005157225,0.0001792895,0.001106951,0.03768151,0.01937417,0.02893426,0.8994427],"study_design_scores_gemma":[0.0000226557,0.0002351245,0.0005887223,0.0006876527,0.00002633871,0.001083786,0.00006961749,0.0002239723,0.0053563,0.003752221,0.9879368,0.00001675204],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001371275,0.9930112,0.0004372483,0.0005989602,0.0003096533,0.000008040937,0.00003405353,0.00002046114,0.004209089],"genre_scores_gemma":[0.00688157,0.9878801,0.0006792623,0.0004492218,0.0003066644,0.000008637498,0.00003808631,0.000003382987,0.003753247],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00376689,"threshold_uncertainty_score":0.01260149,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2163841415","doi":"10.2174/0929867043364720","title":"P-selectin Cell Adhesion Molecule in Inflammation, Thrombosis, Cancer Growth and Metastasis","year":2004,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Cell adhesion; P-selectin; Cell adhesion molecule; Metastasis; Inflammation; Platelet; Selectin; Cancer cell; Cell biology; Cancer research; Adhesion; Cancer; Endothelial stem cell; Platelet activation; Chemistry; Cell; Immunology; Biology; Medicine; In vitro; Biochemistry; Internal medicine","authors":[{"name":"Jian-Guo Geng","is_ca":false},{"name":"Ming Chen","is_ca":true},{"name":"Kuo‐Chen Chou","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06014570945751675,"gpt":0.3957756665475541,"spread":0.3356299570900373,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002967202,0.0006694312,0.0007316484,0.001210654,0.0002719523,0.0007241771,0.0004646965,0.0008844694,0.003524626],"category_scores_gemma":[0.0001957098,0.0001743911,0.0001776555,0.001618547,0.0003697271,0.0009421073,0.0003009329,0.0007737243,0.003544105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004704274,"about_ca_system_score_gemma":0.0006137561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007004971,"about_ca_topic_score_gemma":0.001255488,"domain_scores_codex":[0.9999262,0.00001366504,0.000008024886,0.00001426128,0.00002917436,0.000008708664],"domain_scores_gemma":[0.9999138,0.00002881894,0.00001187524,0.000003284145,0.00002734023,0.00001487053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009137393,0.0001019711,0.0001934997,0.004755201,0.00003452274,0.0003327269,0.00006202867,0.0005307725,0.009393472,0.00477514,0.01760075,0.9621284],"study_design_scores_gemma":[0.0000204598,0.0001638845,0.001078044,0.0007629354,0.00004134495,0.001560029,0.0000714823,0.0001532943,0.002914231,0.00330636,0.9899136,0.00001441736],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004366105,0.996321,0.0003709018,0.0002911797,0.000193012,0.000005558774,0.00001317121,0.000009873072,0.002358704],"genre_scores_gemma":[0.002645978,0.9930521,0.0005546337,0.0001723114,0.0002266235,0.00001000574,0.00002897949,0.000001739229,0.003307663],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003524626,"threshold_uncertainty_score":0.01179105,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2113471632","doi":"10.2174/092986710790980041","title":"Cannabinoid CB2 Receptors in Health and Disease","year":2010,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Cannabinoid receptor type 2; Endocannabinoid system; Cannabinoid receptor; Receptor; Inflammation; Cannabinoid; Immune system; Disease; Gastrointestinal tract; Biology; Neuroscience; Medicine; Immunology; Internal medicine; Agonist","authors":[{"name":"Kamala D. Patel","is_ca":false},{"name":"Joseph S. Davison","is_ca":false},{"name":"Quentin J. Pittman","is_ca":false},{"name":"Keith A. Sharkey","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04392420410942636,"gpt":0.3949553967494613,"spread":0.3510311926400349,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000306354,0.0006524797,0.0008689587,0.001117942,0.0003727144,0.000636976,0.0006623078,0.0008912252,0.00397947],"category_scores_gemma":[0.0002327933,0.0001571426,0.0002350027,0.001187698,0.0005048383,0.0006181546,0.0005193704,0.0008204119,0.002648584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001005415,"about_ca_system_score_gemma":0.001266883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003413558,"about_ca_topic_score_gemma":0.005305764,"domain_scores_codex":[0.9998689,0.00002354662,0.00001212631,0.00002168381,0.00005310455,0.00002059386],"domain_scores_gemma":[0.9999394,0.00001672067,0.000009070885,0.000003091327,0.00001823976,0.00001344354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001562317,0.00007032836,0.0003175476,0.006303631,0.00005548124,0.0006141316,0.0001190363,0.0004577183,0.01140899,0.00882451,0.03025612,0.9414163],"study_design_scores_gemma":[0.00002010016,0.0000658007,0.001729982,0.001257729,0.00004110096,0.001464,0.00008273368,0.0001038961,0.001862292,0.004396116,0.9889575,0.0000188034],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003408917,0.9957373,0.000169625,0.0003131492,0.0001620853,0.000004762811,0.00001443677,0.000009420147,0.003248425],"genre_scores_gemma":[0.003694248,0.9924064,0.0002452047,0.0002176175,0.0002059465,0.000007004669,0.00002613394,0.000001377617,0.003196053],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00397947,"threshold_uncertainty_score":0.0133127,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2122874855","doi":"10.2174/0929867321666140706142930","title":"Hydrogen Sulfide and Endothelial Dysfunction: Relationship with Nitric Oxide","year":2014,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Lakehead University","funders":"Canadian Institutes of Health Research","keywords":"Nitric oxide; Angiogenesis; Endothelium; Endothelial dysfunction; Endothelial stem cell; Homeostasis; Medicine; Pharmacology; Internal medicine; Chemistry; Biochemistry","authors":[{"name":"Zaid Altaany","is_ca":true},{"name":"Francesco Moccia","is_ca":false},{"name":"Luca Munaron","is_ca":false},{"name":"Daniele Mancardi","is_ca":true},{"name":"Rui Wang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03505727787078715,"gpt":0.3089697750007023,"spread":0.2739124971299152,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000308641,0.0006001072,0.0008874781,0.001311965,0.0002608812,0.0007126222,0.0006295491,0.0008908021,0.002217037],"category_scores_gemma":[0.0002746408,0.0001619792,0.000233001,0.001316426,0.0004072661,0.0008256725,0.0005368901,0.001288854,0.001420149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000516468,"about_ca_system_score_gemma":0.0006709414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006062666,"about_ca_topic_score_gemma":0.001033007,"domain_scores_codex":[0.9999142,0.00001538233,0.0000119064,0.00001608001,0.00003169184,0.00001076267],"domain_scores_gemma":[0.9998835,0.00004330694,0.00001805273,0.000003409576,0.0000307491,0.00002103603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009504358,0.0001129651,0.0003125803,0.009954229,0.0000765097,0.0003795137,0.00006270278,0.0002649075,0.002754458,0.004773027,0.02970983,0.9515043],"study_design_scores_gemma":[0.00002650057,0.0001886502,0.001894855,0.00220732,0.00009927023,0.00283864,0.00008679387,0.0001836081,0.001343539,0.003822135,0.9872832,0.00002548863],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001618419,0.9986458,0.00009701986,0.0002990589,0.0001608866,0.000002740599,0.000008829921,0.000005883993,0.0006178628],"genre_scores_gemma":[0.001088483,0.9979563,0.0001074303,0.0001310768,0.0002247533,0.000004793699,0.00001645062,8.626604e-7,0.0004698444],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002217037,"threshold_uncertainty_score":0.007416666,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1970524486","doi":"10.2174/0929867033457340","title":"Synthetic Vaccines: The Role of Adjuvants in Immune Targeting","year":2003,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Immune system; Acquired immune system; Innate immune system; Adjuvant; Immunity; Biology; Pattern recognition receptor; Pathogen-associated molecular pattern; Immunology; Epitope; Antibody","authors":[{"name":"Zi‐Hua Jiang","is_ca":true},{"name":"R. Rao Koganty","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01941614466980147,"gpt":0.3006365545930442,"spread":0.2812204099232427,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001585932,0.0005481743,0.0007122875,0.0005389497,0.0002318681,0.001232042,0.0005363408,0.001520055,0.002225904],"category_scores_gemma":[0.001213379,0.0003123739,0.0003262718,0.0002859863,0.001287613,0.002261174,0.000853123,0.002013125,0.0009541529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008052837,"about_ca_system_score_gemma":0.0005141713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002159305,"about_ca_topic_score_gemma":0.0001569804,"domain_scores_codex":[0.9994784,0.0002395649,0.0000258373,0.00007926832,0.0001194205,0.00005760567],"domain_scores_gemma":[0.9994581,0.0002641773,0.0001025168,0.0000298476,0.00007960049,0.00006578445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007807199,0.0005044715,0.0005501895,0.005700422,0.00008541052,0.000600686,0.0002686892,0.008701549,0.2707741,0.2626302,0.007263621,0.44214],"study_design_scores_gemma":[0.0002569902,0.004477697,0.0008050977,0.001517294,0.00008875441,0.001504903,0.0002205278,0.009619488,0.2037245,0.1194005,0.6582636,0.0001206375],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04200685,0.8484052,0.07576617,0.009086905,0.003028,0.0002578206,0.0001657242,0.000233395,0.02105002],"genre_scores_gemma":[0.3838204,0.5391154,0.05007874,0.005283406,0.002695736,0.0005740185,0.0002647642,0.0001239096,0.0180435],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002225904,"threshold_uncertainty_score":0.008387327,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2156929885","doi":"10.2174/092986712799034897","title":"Non Polymeric Nanoparticles for Photodynamic Therapy Applications: Recent Developments","year":2012,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":86,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre d'expertise et de recherche en infrastructures urbaines","funders":"","keywords":"Photodynamic therapy; Nanoparticle; Nanotechnology; Materials science; Chemistry; Organic chemistry","authors":[{"name":"Rima Chouikrat","is_ca":false},{"name":"Aymeric Sève","is_ca":false},{"name":"Régis Vanderesse","is_ca":false},{"name":"Hamanou Benachour","is_ca":true},{"name":"Muriel Barberi‐Heyob","is_ca":true},{"name":"Sébastien Richeter","is_ca":false},{"name":"Laurence Raehm","is_ca":false},{"name":"Jean-Olivier Durand","is_ca":false},{"name":"Marc Verelst","is_ca":false},{"name":"Céline Frochot","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05414206023517745,"gpt":0.3259453712059507,"spread":0.2718033109707733,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004401915,0.0007978992,0.000686452,0.001561149,0.0002351383,0.0007420923,0.0005284008,0.001006461,0.003036349],"category_scores_gemma":[0.0003035861,0.0002836328,0.0003039249,0.001635461,0.0003480286,0.001067529,0.0005065379,0.0009909222,0.002639246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003874935,"about_ca_system_score_gemma":0.0005189355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005575715,"about_ca_topic_score_gemma":0.0007427864,"domain_scores_codex":[0.9998413,0.00001823684,0.00001538487,0.00003656313,0.00007365872,0.00001480244],"domain_scores_gemma":[0.9998257,0.00006937877,0.00002759415,0.000007562154,0.00005405889,0.00001568341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005426916,0.0001494167,0.0001274967,0.01111152,0.00003796787,0.0002332073,0.00007924904,0.0005595795,0.024711,0.005037116,0.01146145,0.9464377],"study_design_scores_gemma":[0.00001266049,0.0001744643,0.0004346701,0.0008444232,0.00005091348,0.001596491,0.00004408035,0.0002977963,0.009225111,0.001604838,0.9856923,0.0000223555],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000569249,0.9954758,0.0008897702,0.0001791156,0.0001408676,0.00001057332,0.00001582325,0.00001758931,0.00270119],"genre_scores_gemma":[0.003180575,0.9926748,0.001128339,0.0001819352,0.0001781176,0.0000168329,0.00003727812,0.000005213086,0.002597056],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003036349,"threshold_uncertainty_score":0.01015759,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1976085304","doi":"10.2174/092986710791959701","title":"10-20 Joules as a Neuromolecular Quantum in Medicinal Chemistry: An Alternative Approach to Myriad Molecular Pathways?","year":2010,"lang":"en","type":"article","venue":"Current Medicinal Chemistry","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Laurentian University","funders":"","keywords":"Chemistry; Quantum chemistry; Computational chemistry; Organic chemistry; Molecule","authors":[{"name":"Michael A. Persinger","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0251024377002539,"gpt":0.3203826443730204,"spread":0.2952802066727666,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001256346,0.0005392218,0.0009693811,0.0004827285,0.001183758,0.002497558,0.001758866,0.002925531,0.01311905],"category_scores_gemma":[0.001690399,0.000344132,0.0004054153,0.0005966258,0.008812408,0.009104066,0.002267136,0.003874254,0.002451929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00158205,"about_ca_system_score_gemma":0.0009549627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003388302,"about_ca_topic_score_gemma":0.0006042894,"domain_scores_codex":[0.9995965,0.0001425105,0.00002324941,0.00008031782,0.0001140654,0.00004336807],"domain_scores_gemma":[0.9995556,0.0001860965,0.00004414822,0.0001126001,0.00004605958,0.00005533362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00006969436,0.00004290745,0.00006657427,0.0002228831,0.000007390343,0.000081463,0.0001665047,0.0006941867,0.005050856,0.9731102,0.002325416,0.01816195],"study_design_scores_gemma":[0.00002949102,0.0001336369,0.00006337021,0.000101202,0.000008823244,0.0002203912,0.0002038309,0.002678289,0.003143196,0.9344724,0.05891488,0.00003047044],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.05479747,0.1237761,0.3733783,0.2117458,0.01974934,0.000239355,0.00029229,0.001096047,0.2149254],"genre_scores_gemma":[0.6962563,0.0624674,0.1606126,0.02356329,0.005823802,0.0005233737,0.0001193174,0.0003391387,0.05029479],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01311905,"threshold_uncertainty_score":0.04388756,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2613054901","doi":"10.2174/0929867324666170509145240","title":"Metabolic Imbalance of Homocysteine and Hydrogen Sulfide in Kidney Disease","year":2017,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Cystathionine beta synthase; Cystathionine gamma-lyase; Transsulfuration; Homocysteine; Kidney; Hyperhomocysteinemia; Internal medicine; Kidney disease; Chemistry; Biochemistry; Endocrinology; Methionine; Medicine; Amino acid","authors":[{"name":"O Karmin","is_ca":true},{"name":"Yaw L. Siow","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09280794728524926,"gpt":0.4198670166859362,"spread":0.3270590694006869,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000416843,0.0003209818,0.000773515,0.001328687,0.000353459,0.0008876903,0.0003028304,0.000698967,0.001318165],"category_scores_gemma":[0.0005407311,0.0001140362,0.0005233802,0.0009768696,0.0002919217,0.0006602961,0.0005731923,0.0006883732,0.0003833071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007406171,"about_ca_system_score_gemma":0.001083413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001271319,"about_ca_topic_score_gemma":0.001667466,"domain_scores_codex":[0.9996812,0.00007915983,0.00007803289,0.00005092353,0.00007514749,0.00003547307],"domain_scores_gemma":[0.999799,0.00005383925,0.00005945163,0.000004307688,0.000056482,0.00002689826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009057677,0.0002931099,0.03332087,0.02234154,0.0006750962,0.007972049,0.00133275,0.0007607986,0.02185366,0.01116586,0.03326938,0.8661091],"study_design_scores_gemma":[0.00007049476,0.001021724,0.06394112,0.007692523,0.001487144,0.04401223,0.00132665,0.0009095666,0.01566683,0.01208792,0.8516408,0.0001430411],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005865925,0.9897206,0.0004295646,0.001561343,0.0003412317,0.000009438247,0.00004720411,0.00001571132,0.002008853],"genre_scores_gemma":[0.03752372,0.9581558,0.0008453029,0.0006455913,0.001046202,0.00001919659,0.0001169454,0.000005121372,0.001642102],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001328687,"threshold_uncertainty_score":0.005373597,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1986284965","doi":"10.2174/092986706778773040","title":"Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and COPD","year":2006,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Rolipram; Roflumilast; Phosphodiesterase; Pharmacology; Chemistry; Theophylline; Biochemistry; Medicine; Enzyme; Internal medicine; COPD","authors":[{"name":"Zheng Huang","is_ca":true},{"name":"Joseph A. Mancini","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03328601926218243,"gpt":0.3330298952458123,"spread":0.2997438759836298,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003657917,0.0004539494,0.0008145009,0.0005488464,0.0002120173,0.0005680115,0.0003797057,0.0009783356,0.005553848],"category_scores_gemma":[0.0003409649,0.00009783987,0.0007353044,0.0004285053,0.0002129539,0.000338335,0.0004177289,0.002108552,0.002217485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003599584,"about_ca_system_score_gemma":0.0004195675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006317954,"about_ca_topic_score_gemma":0.002741982,"domain_scores_codex":[0.9998221,0.00003686405,0.00001796131,0.00002466787,0.00006979888,0.00002855414],"domain_scores_gemma":[0.999844,0.00002474353,0.00005058169,0.00000460226,0.00003551594,0.00004057479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001818435,0.000693825,0.001077508,0.003993918,0.0003023517,0.0007848463,0.00007454411,0.0003238717,0.02546811,0.003595696,0.08602595,0.8758409],"study_design_scores_gemma":[0.001818887,0.002889916,0.01230499,0.001584381,0.0004042626,0.003481249,0.00009196051,0.0006567382,0.004654645,0.00289656,0.9691742,0.00004218004],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007619929,0.9707502,0.000976336,0.006568652,0.001427721,0.000105651,0.0003711954,0.0001627244,0.01201764],"genre_scores_gemma":[0.09469098,0.8527974,0.005774757,0.01053333,0.002920015,0.0003617513,0.001374822,0.00004963078,0.03149735],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005553848,"threshold_uncertainty_score":0.01857942,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2159068988","doi":"10.2174/0929867023371102","title":"Methionine In and Out of Proteins: Targets for Drug Design","year":2002,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Enzyme; Methionine; Biochemistry; Antibiotics; Drug development; Biology; Drug discovery; Computational biology; Aminopeptidase; Amino acid; Drug; Chemistry; Pharmacology","authors":[{"name":"Mark D. Vaughan","is_ca":true},{"name":"Peter B. Sampson","is_ca":false},{"name":"John F. Honek","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1317090353319891,"gpt":0.3967242398192432,"spread":0.265015204487254,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004411198,0.001018743,0.001594662,0.001306058,0.0002856418,0.000906061,0.0009143192,0.001112209,0.002906439],"category_scores_gemma":[0.0002598951,0.000330658,0.0003804498,0.001134927,0.0005823305,0.001703036,0.0004724312,0.001633951,0.003303498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006868012,"about_ca_system_score_gemma":0.0005201909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003510281,"about_ca_topic_score_gemma":0.0008134231,"domain_scores_codex":[0.9998522,0.00002885156,0.00001261996,0.00002578564,0.00006110778,0.00001932991],"domain_scores_gemma":[0.9999143,0.00002901326,0.00001535771,0.000005344154,0.00002036308,0.00001561391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00021921,0.0002136587,0.0001773514,0.007261685,0.00007113286,0.0007803121,0.0001243196,0.002528364,0.03333217,0.02092306,0.02960799,0.9047607],"study_design_scores_gemma":[0.0001021134,0.000283474,0.0003629058,0.0008605575,0.00004907564,0.001660029,0.00007377461,0.0007797002,0.007061698,0.009780192,0.9789613,0.00002513878],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001235433,0.988979,0.003259477,0.001168905,0.0004601103,0.00003309102,0.00005013325,0.00006130662,0.004752414],"genre_scores_gemma":[0.006339616,0.9859269,0.002963896,0.0006753945,0.0002854542,0.00004014494,0.00008204686,0.000007332778,0.00367915],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002906439,"threshold_uncertainty_score":0.009723008,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2116528202","doi":"10.2174/0929867311320030011","title":"Abnormal Striatal Dopamine Transmission in Schizophrenia","year":2013,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"National Institutes of Health","keywords":"Neurochemical; Dopamine; Positron emission tomography; Schizophrenia (object-oriented programming); Striatum; Neuroscience; Psychology; Medicine; Ventral striatum; Psychiatry","authors":[{"name":"Jérôme Brunelin","is_ca":false},{"name":"Shirley Fecteau","is_ca":true},{"name":"Marie‐Françoise Suaud‐Chagny","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06142212114507414,"gpt":0.3713927777339057,"spread":0.3099706565888316,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003009926,0.000520244,0.0007935045,0.001739781,0.0002246915,0.0005907022,0.0004517611,0.0006529434,0.002206297],"category_scores_gemma":[0.0002513533,0.0002291912,0.0003002246,0.001391699,0.0003149321,0.0005786303,0.0005196968,0.0008449511,0.001141477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005284159,"about_ca_system_score_gemma":0.0009240311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00233054,"about_ca_topic_score_gemma":0.004640201,"domain_scores_codex":[0.99993,0.00001167625,0.00001442581,0.00001370848,0.00002359608,0.000006610182],"domain_scores_gemma":[0.9999268,0.00002694692,0.00001518836,0.000002755575,0.00001969667,0.000008693127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006672696,0.0000429271,0.0002439838,0.01493815,0.00007836808,0.0004809854,0.00008380595,0.0003058176,0.002682904,0.002783547,0.01428615,0.9640066],"study_design_scores_gemma":[0.00002675616,0.0001072299,0.003455216,0.004446741,0.0001380208,0.004714073,0.0001126803,0.0001876624,0.001108748,0.003098504,0.9825736,0.00003062418],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001980901,0.9987801,0.00006320546,0.0001522314,0.00005413379,0.000002744907,0.00001458527,0.000004191523,0.0007307777],"genre_scores_gemma":[0.001121699,0.9982673,0.0001025488,0.00007032085,0.00005251901,0.000003317455,0.00001611602,7.331957e-7,0.0003653947],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00233054,"threshold_uncertainty_score":0.007380784,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2883070899","doi":"10.2174/0929867325666180718164712","title":"Cancer Biomarker Discovery for Precision Medicine: New Progress","year":2018,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Cancer; Biomarker discovery; Precision medicine; Biomarker; Medicine; Computational biology; Computer science; Medical physics; Data science; Internal medicine; Biology; Pathology; Proteomics; Genetics","authors":[{"name":"Jinfeng Zou","is_ca":true},{"name":"Edwin Wang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06673842857917817,"gpt":0.4096157975974735,"spread":0.3428773690182953,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003429521,0.001295366,0.001792224,0.003562736,0.0006373692,0.002617976,0.001452781,0.003039339,0.003679937],"category_scores_gemma":[0.003887803,0.0004807509,0.001171978,0.003268791,0.002278355,0.004307784,0.001680039,0.006138985,0.001924093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002373142,"about_ca_system_score_gemma":0.003058256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00121517,"about_ca_topic_score_gemma":0.001196673,"domain_scores_codex":[0.9986499,0.0003456477,0.0001340149,0.0002252351,0.0005499718,0.0000952166],"domain_scores_gemma":[0.9960676,0.002553932,0.0002539982,0.0001496301,0.0007695978,0.000205265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000671624,0.00007656666,0.000295285,0.01612453,0.0001680538,0.0003032876,0.0002028932,0.0008604932,0.00196847,0.05364053,0.06959096,0.8567018],"study_design_scores_gemma":[0.00001215099,0.00006515673,0.0002829035,0.003044538,0.00007230401,0.0009208814,0.00008470085,0.0002808781,0.0006422269,0.02031405,0.9742467,0.0000335135],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009307956,0.9932907,0.001262698,0.003167755,0.0008383235,0.000007215932,0.0000209492,0.00002618126,0.001293063],"genre_scores_gemma":[0.001599463,0.9938627,0.001296857,0.001402577,0.001160717,0.00001458082,0.00003422162,0.000005837289,0.000623003],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003679937,"threshold_uncertainty_score":0.01813722,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049416454","doi":"10.2174/092986706775197908","title":"Natural and Synthetic Biologically Active Dimeric Molecules: Anticancer Agents, Anti-HIV Agents, Steroid Derivatives and Opioid Antagonists","year":2005,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biological activity; Steroid; Chemistry; Human immunodeficiency virus (HIV); Pharmacology; Stereochemistry; Combinatorial chemistry; Biology; Biochemistry; In vitro; Virology; Hormone","authors":[{"name":"Gervais Bérubé","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05367470736058108,"gpt":0.339689319133093,"spread":0.2860146117725119,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001899458,0.0004880427,0.0005385523,0.0008328065,0.0002009883,0.0004512428,0.0004543928,0.0005044396,0.003675466],"category_scores_gemma":[0.0001243961,0.0001787748,0.0001438751,0.0008526256,0.0002886246,0.0007529541,0.0002436497,0.0006860116,0.003730887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004098926,"about_ca_system_score_gemma":0.00040347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003269319,"about_ca_topic_score_gemma":0.0007335359,"domain_scores_codex":[0.999938,0.000008720835,0.000005686538,0.00001328221,0.00002569897,0.000008486576],"domain_scores_gemma":[0.9999542,0.00001221934,0.00001025053,0.000002760527,0.00001259617,0.000007929089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001153947,0.0002218812,0.000148308,0.009228517,0.00003156894,0.0003465843,0.000101816,0.0006975363,0.06472685,0.01019994,0.01324524,0.9009364],"study_design_scores_gemma":[0.00002485859,0.0002410842,0.000534884,0.0003932886,0.0000281797,0.001596917,0.00005635899,0.0001807924,0.01627598,0.001903786,0.9787476,0.00001629688],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002391938,0.9854823,0.002018911,0.0002628048,0.0002565715,0.00002701352,0.00004654458,0.00004047513,0.009473292],"genre_scores_gemma":[0.01325278,0.9730209,0.002724719,0.0003269358,0.0002193901,0.00003319059,0.00009743802,0.000007304827,0.01031732],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003675466,"threshold_uncertainty_score":0.01229566,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071947905","doi":"10.2174/0929867033456585","title":"Novel Hydroxamate and Anilide Derivatives as Potent Histone Deacetylase Inhibitors: Synthesis and Antiproliferative Evaluation","year":2003,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Pyrogenesis (Canada)","funders":"","keywords":"Histone deacetylase; Trichostatin A; Hydroxamic acid; Acetylation; Cell growth; Histone; Chemistry; Cell cycle; Cancer cell; Histone deacetylase inhibitor; Histone deacetylase 5; Histone deacetylase 2; Cell cycle checkpoint; Biochemistry; Cancer research; Biology; Cancer; Cell; Gene; Genetics; Stereochemistry","authors":[{"name":"Giliane Bouchain","is_ca":true},{"name":"Daniel Delorme","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05243561106004767,"gpt":0.3938725110748181,"spread":0.3414369000147704,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001474514,0.0006224847,0.0003606212,0.0003823457,0.0001267699,0.0002209499,0.000430723,0.0003071091,0.002967169],"category_scores_gemma":[0.00009933757,0.0001451451,0.0002028531,0.0002835517,0.0001453579,0.0003284634,0.0001882598,0.000478442,0.0008029355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002981099,"about_ca_system_score_gemma":0.0002004759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000486862,"about_ca_topic_score_gemma":0.0008849575,"domain_scores_codex":[0.9999545,0.000007317436,0.00000497371,0.00000889463,0.00001161023,0.00001279063],"domain_scores_gemma":[0.9999529,0.000006220129,0.00001006735,0.000003348686,0.000009321797,0.00001819862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004713773,0.0004555512,0.0001790325,0.0008121555,0.00004171899,0.0002848791,0.00007548228,0.001850267,0.8989426,0.001792056,0.00112189,0.09397295],"study_design_scores_gemma":[0.0005146828,0.01017987,0.003597605,0.0001103351,0.0001615505,0.001223299,0.00004853234,0.00229721,0.8639401,0.0004845606,0.1173899,0.00005232371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6539374,0.2759183,0.02859776,0.0006838674,0.0006548035,0.0009979287,0.001773484,0.0006511658,0.0367852],"genre_scores_gemma":[0.7828754,0.185755,0.0141863,0.0003776623,0.0003365183,0.0003242345,0.001520472,0.00005515164,0.01456934],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002967169,"threshold_uncertainty_score":0.0099262,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2147859611","doi":"10.2174/092986709789712899","title":"Pituitary Adenylate Cyclase-Activating Polypeptide: Focus on Structure- Activity Relationships of a Neuroprotective Peptide","year":2009,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":76,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Agence Nationale de la Recherche; Institut National de la Santé et de la Recherche Médicale; Institut national de la recherche scientifique","keywords":"Neuroprotection; Receptor; Pituitary adenylate cyclase-activating peptide; Adenylate kinase; Pharmacology; Chemistry; In vivo; Peptide; Cyclase; Neuropeptide; Neuroscience; Cell biology; Biochemistry; Biology; Vasoactive intestinal peptide","authors":[{"name":"Steve Bourgault","is_ca":false},{"name":"David Vaudry","is_ca":false},{"name":"Agnieszka Dejda","is_ca":false},{"name":"Ninh Doan","is_ca":true},{"name":"Hubert Vaudry","is_ca":false},{"name":"Alain Fournier","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1262111272593446,"gpt":0.3543711271224261,"spread":0.2281599998630815,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002387069,0.0007927918,0.0008699744,0.0009978679,0.0001898872,0.0005178598,0.0005342652,0.0006299846,0.002378499],"category_scores_gemma":[0.0001662484,0.0002366987,0.0002636435,0.001516151,0.0003231243,0.0009607326,0.0003454871,0.001062119,0.002558734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005511267,"about_ca_system_score_gemma":0.0004756049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005113407,"about_ca_topic_score_gemma":0.00066149,"domain_scores_codex":[0.9999324,0.000008208037,0.000008588981,0.00001807114,0.00002508854,0.000007693109],"domain_scores_gemma":[0.9999324,0.00002149338,0.00001348768,0.00000299543,0.00001957792,0.00001006414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001493773,0.0002353821,0.0001753607,0.01451288,0.00006229229,0.0008746305,0.00009059447,0.001287102,0.05888486,0.008427665,0.01465976,0.9006401],"study_design_scores_gemma":[0.00004290848,0.0003540429,0.001232497,0.001047422,0.00008394312,0.003147942,0.00005519129,0.0003128374,0.01217013,0.003116438,0.9784099,0.00002671611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001019091,0.9940508,0.0006899401,0.0001775947,0.0001582042,0.000009520836,0.00002770984,0.00001311457,0.003854093],"genre_scores_gemma":[0.004193045,0.9918405,0.001019823,0.000181871,0.0002024081,0.00001459676,0.00006725466,0.000003319429,0.002477251],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002378499,"threshold_uncertainty_score":0.007956862,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1986125636","doi":"10.2174/092986709788682218","title":"1,5-Diaryl-3-oxo-1,4-pentadienes: A Case for Antineoplastics with Multiple Targets","year":2009,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":73,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Moiety; Chemistry; Stereochemistry; Enzyme; Molecule; Combinatorial chemistry; Molecular model; In vitro; In vivo; Cytotoxicity; Biochemistry; Organic chemistry; Biology","authors":[{"name":"Umashankar Das","is_ca":true},{"name":"Rajendra K. Sharma","is_ca":true},{"name":"J.R. Dimmock","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06709664724713132,"gpt":0.333431550305903,"spread":0.2663349030587717,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008322409,0.0003559646,0.0009329528,0.0005836923,0.0003058524,0.001420249,0.0007653083,0.001790094,0.001817729],"category_scores_gemma":[0.000636796,0.0002236474,0.0003119772,0.0006917366,0.001462562,0.003457954,0.0007598375,0.002807136,0.00121318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007249874,"about_ca_system_score_gemma":0.000473457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002301215,"about_ca_topic_score_gemma":0.0006609096,"domain_scores_codex":[0.9997351,0.00007987917,0.00002689226,0.00005640487,0.00006242658,0.00003922964],"domain_scores_gemma":[0.999725,0.0001378985,0.00003449143,0.00001967304,0.00004857303,0.00003426469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003579454,0.0001744196,0.0006062762,0.01128528,0.0001089884,0.01013064,0.001612411,0.001731634,0.08460419,0.3243801,0.0358198,0.5291883],"study_design_scores_gemma":[0.00001781324,0.0002059782,0.0002538395,0.0005925596,0.00003845672,0.008109137,0.0003088542,0.0002923102,0.005000416,0.02372102,0.961436,0.0000235222],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005189485,0.9658129,0.006984025,0.006895063,0.002062188,0.00002708496,0.00002706074,0.00005416855,0.01294812],"genre_scores_gemma":[0.03762093,0.9209156,0.01041637,0.008720928,0.002053353,0.00007049627,0.00005936584,0.0000408856,0.02010215],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001817729,"threshold_uncertainty_score":0.006080925,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2123831346","doi":"10.2174/0929867024606678","title":"Heterocyclic Compounds as Inflammation Inhibitors","year":2002,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":72,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Benzimidazole; Nonsteroidal; Pharmacology; Chemistry; Thiazole; Thiazolidine; Anti-inflammatory; Inflammation; Thiourea; Gastrointestinal tract; Toxicity; Medicine; Biochemistry; Stereochemistry; Immunology; Organic chemistry","authors":[{"name":"Sham M. Sondhi","is_ca":false},{"name":"Nidhi Singhl","is_ca":false},{"name":"Monika Johar","is_ca":false},{"name":"B. Sreekanth Reddy","is_ca":false},{"name":"J. William Lown","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08194231051851487,"gpt":0.3372896158540771,"spread":0.2553473053355622,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001392881,0.0005157499,0.00050521,0.0008505856,0.0002052504,0.000390166,0.00048318,0.0004590678,0.004700165],"category_scores_gemma":[0.00009435593,0.000139246,0.0001739968,0.0007885687,0.000249584,0.0005268104,0.0002815674,0.0005849757,0.003535314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003007081,"about_ca_system_score_gemma":0.0002986521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004835823,"about_ca_topic_score_gemma":0.0009477721,"domain_scores_codex":[0.9999329,0.00001011252,0.000004734882,0.00001673163,0.00002523608,0.00001027589],"domain_scores_gemma":[0.999966,0.00000778447,0.000008112296,0.000002690005,0.000009862459,0.000005501076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000220821,0.0002308827,0.0002332432,0.00824597,0.00004757151,0.0005775512,0.0001245267,0.001458605,0.1034615,0.01270601,0.01121536,0.861478],"study_design_scores_gemma":[0.00004834208,0.0004968655,0.001226405,0.0005286272,0.00005264124,0.001496933,0.00005063608,0.0003291801,0.0360246,0.00265584,0.9570667,0.00002323858],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005455553,0.9746509,0.001733943,0.000204731,0.0003921143,0.00003673657,0.0000915397,0.00005036002,0.01738408],"genre_scores_gemma":[0.02850149,0.9557421,0.001740964,0.0003365514,0.0002547829,0.00004534774,0.0001631295,0.000009428787,0.0132061],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004700165,"threshold_uncertainty_score":0.01572359,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2589777195","doi":"10.2174/0929867324666170209104926","title":"Targeting Melatonin MT2 Receptors: A Novel Pharmacological Avenue for Inflammatory and Neuropathic Pain","year":2017,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":65,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Rostral ventromedial medulla; Neuropathic pain; Analgesic; Receptor; Pharmacology; Melatonin; Nociception; Neuroscience; Chronic pain; Melatonin receptor; Medicine; Partial agonist; Agonist; Hyperalgesia; Biology; Internal medicine","authors":[{"name":"Luca Posa","is_ca":true},{"name":"Danilo De Gregorio","is_ca":true},{"name":"Gabriella Gobbi","is_ca":true},{"name":"Stefano Comai","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1409161471260586,"gpt":0.3847370807559401,"spread":0.2438209336298815,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002011562,0.0004737274,0.0005549261,0.0005164999,0.0001857112,0.0004654532,0.0003663076,0.0006267913,0.001763974],"category_scores_gemma":[0.00009428344,0.0001268864,0.0004830981,0.0002824695,0.0002497192,0.0004259376,0.0003475479,0.0009561007,0.0004017429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003016102,"about_ca_system_score_gemma":0.0003290962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003819149,"about_ca_topic_score_gemma":0.00144974,"domain_scores_codex":[0.9999437,0.000009439503,0.000004531386,0.00001163278,0.00001446487,0.00001629143],"domain_scores_gemma":[0.9999754,0.000003444193,0.000006592803,0.000001482038,0.000006194458,0.000006825338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001031618,0.0003660493,0.000833315,0.0122044,0.0002467342,0.001601035,0.0002224987,0.0007237246,0.5645527,0.01016473,0.01297685,0.3950763],"study_design_scores_gemma":[0.0008937353,0.0061137,0.009546008,0.001060338,0.0008028282,0.005216314,0.0001640816,0.001954794,0.1217575,0.006292025,0.846095,0.0001035332],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03505298,0.9461629,0.007415419,0.002409362,0.0009875502,0.0001549043,0.0002210047,0.0002280845,0.00736795],"genre_scores_gemma":[0.2016997,0.78091,0.006646028,0.001977406,0.001348387,0.0001731,0.0004863497,0.00002783204,0.006731293],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001763974,"threshold_uncertainty_score":0.005901039,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136403146","doi":"10.2174/0929867322666150416095744","title":"Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion","year":2015,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Beetle Biology and Toxicology Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Tamoxifen; Breast cancer; PTEN; Medicine; Cancer research; PI3K/AKT/mTOR pathway; Cancer; Estrogen receptor; Oncology; Internal medicine; Metastasis; Adjuvant therapy; Cancer stem cell; Bioinformatics; Biology; Signal transduction","authors":[{"name":"Diane Ojo","is_ca":false},{"name":"Fengxiang Wei","is_ca":false},{"name":"Yun Liu","is_ca":false},{"name":"Enli Wang","is_ca":false},{"name":"Hongde Zhang","is_ca":false},{"name":"Xiaozeng Lin","is_ca":false},{"name":"Nicholas Wong","is_ca":false},{"name":"Anita Bane","is_ca":false},{"name":"Damu Tang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06011176159515599,"gpt":0.3565391721350993,"spread":0.2964274105399433,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000195328,0.0002793766,0.0003778081,0.0006714817,0.0001277295,0.0005153224,0.0002101392,0.0003342541,0.001705354],"category_scores_gemma":[0.0002337941,0.0001027031,0.0003229863,0.000411063,0.0001664501,0.0003180881,0.0002428253,0.000633142,0.0006968842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002604416,"about_ca_system_score_gemma":0.0003055918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003168529,"about_ca_topic_score_gemma":0.0007822676,"domain_scores_codex":[0.9999197,0.00001536547,0.00001020337,0.00001289117,0.00002787607,0.00001395143],"domain_scores_gemma":[0.9999264,0.00002797232,0.00001623287,0.00000258861,0.00001714052,0.000009625945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003653913,0.0002816945,0.001977737,0.0137073,0.000146749,0.001215957,0.0003606227,0.00066625,0.2586717,0.006874731,0.01532799,0.7004039],"study_design_scores_gemma":[0.000126176,0.001430997,0.01510281,0.00113024,0.0005416549,0.003823005,0.0002991036,0.0007586093,0.1190753,0.002081465,0.8555626,0.00006796372],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03036977,0.9589507,0.002002167,0.0009327157,0.0004838976,0.00006862394,0.0002137698,0.0001240538,0.006854435],"genre_scores_gemma":[0.0882524,0.9033445,0.002019071,0.0007608921,0.0005703788,0.0000930918,0.0005133201,0.00002148584,0.004424879],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001705354,"threshold_uncertainty_score":0.005704939,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2166622264","doi":"10.2174/092986706776055733","title":"Thiol Proteases: Inhibitors and Potential Therapeutic Targets","year":2006,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Proteases; Cysteine protease; Transplantation; Cysteine; Pharmacology; Protease; Medicine; Biology; Chemistry; Enzyme; Biochemistry; Internal medicine","authors":[{"name":"Régis Leung-Toung","is_ca":true},{"name":"Yanqing Zhao","is_ca":false},{"name":"Wanren Li","is_ca":false},{"name":"Tim F. Tam","is_ca":false},{"name":"Khashayar Karimian","is_ca":false},{"name":"Michael Spino","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01803526883446711,"gpt":0.301526886334503,"spread":0.2834916175000359,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006348941,0.001247423,0.001648357,0.002651754,0.000340188,0.001022992,0.001050824,0.001380482,0.003824153],"category_scores_gemma":[0.0005069458,0.0003964576,0.0005194767,0.001824214,0.0005557209,0.001722573,0.0005803605,0.002497179,0.002756318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007165853,"about_ca_system_score_gemma":0.0005122371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005437373,"about_ca_topic_score_gemma":0.001259972,"domain_scores_codex":[0.9997861,0.00003125881,0.000024017,0.0000435263,0.00008896215,0.0000261281],"domain_scores_gemma":[0.9998376,0.00006472264,0.00002532719,0.000007383677,0.00004161032,0.00002341632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001520329,0.000221915,0.0001073227,0.007443199,0.00007017273,0.0005405435,0.00008622672,0.0006785776,0.006299335,0.004752285,0.02722213,0.9524262],"study_design_scores_gemma":[0.00008333055,0.0002642066,0.0005911788,0.001672068,0.00006767461,0.002240145,0.00006391734,0.0002020491,0.001822171,0.003057258,0.9899128,0.00002312025],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002103119,0.9977576,0.00023768,0.0002462305,0.0002033512,0.000007856289,0.00001477988,0.00001326964,0.001308862],"genre_scores_gemma":[0.00107701,0.9965872,0.0003989897,0.0002369043,0.0001891037,0.00001558082,0.00003363184,0.00000269051,0.00145888],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003824153,"threshold_uncertainty_score":0.01279306,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109612910","doi":"10.2174/0929867310504050599","title":"Molecular Actions of Polyhalogenated Arylhydrocarbons (PAHs) in Female Reproduction","year":2005,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":60,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Reproduction; Chemistry; Biology; Ecology","authors":[{"name":"Sabine Hombach‐Klonisch","is_ca":true},{"name":"Paola Pocar","is_ca":false},{"name":"Silke Kietz","is_ca":true},{"name":"Thomas Klonisch","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04959652786970566,"gpt":0.3469138916562374,"spread":0.2973173637865317,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242097,0.0004871775,0.0004520706,0.0006931694,0.0001807165,0.0003455293,0.0003790623,0.0006000455,0.002614059],"category_scores_gemma":[0.0001237817,0.00009693138,0.000166456,0.0008388166,0.0002042288,0.0003849893,0.0001906235,0.0002968308,0.001472868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000354994,"about_ca_system_score_gemma":0.0003795094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009677049,"about_ca_topic_score_gemma":0.001605502,"domain_scores_codex":[0.9999374,0.00001015255,0.000006413035,0.00001063066,0.00002671953,0.00000860974],"domain_scores_gemma":[0.9999526,0.00001447329,0.000009233008,0.000001904569,0.00001631845,0.000005592215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001316755,0.0001010034,0.0006290212,0.007571907,0.00005888214,0.0006753994,0.00009153338,0.0007438685,0.03164404,0.002930401,0.01007174,0.9453505],"study_design_scores_gemma":[0.00002481983,0.0003326099,0.006988465,0.0009497026,0.000114027,0.003990179,0.0001337506,0.0001820907,0.01297837,0.002040429,0.9722448,0.00002077516],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001813096,0.9938836,0.0003215288,0.0001595199,0.0001161925,0.000005680521,0.00002532707,0.00001090044,0.003664267],"genre_scores_gemma":[0.008997378,0.987677,0.0003087269,0.0001004924,0.0001172327,0.000006654987,0.00003970925,9.851425e-7,0.002751675],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002614059,"threshold_uncertainty_score":0.008744895,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2147291281","doi":"10.2174/092986710792927886","title":"Insights into the Molecular Mechanism of hERG1 Channel Activation and Blockade by Drugs","year":2010,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"hERG; Pharmacology; Potassium channel; QT interval; Astemizole; Blockade; Long QT syndrome; Repolarization; Chemistry; Ion channel; Cardiac action potential; Potassium channel blocker; Medicine; Internal medicine; Electrophysiology; Receptor","authors":[{"name":"Serdar Durdağı","is_ca":true},{"name":"Julia Subbotina","is_ca":false},{"name":"James P. Lees‐Miller","is_ca":false},{"name":"Jia Guo","is_ca":false},{"name":"Henry J. Duff","is_ca":false},{"name":"Sergei Y. Noskov","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01160378060921945,"gpt":0.2945021789218421,"spread":0.2828983983126226,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002330745,0.0006532572,0.0004797916,0.0002027434,0.0001942433,0.0006230616,0.0006168778,0.0007264249,0.00165112],"category_scores_gemma":[0.0002036946,0.0002288317,0.0005463314,0.0001630987,0.0004164171,0.00114733,0.0002681204,0.001409115,0.000522954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00050456,"about_ca_system_score_gemma":0.000472587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005665511,"about_ca_topic_score_gemma":0.0004721925,"domain_scores_codex":[0.9998815,0.00002509743,0.000006326083,0.00002020285,0.00003961702,0.00002723373],"domain_scores_gemma":[0.9999543,0.0000189524,0.000008912765,0.00000414307,0.000008707564,0.000004959949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003599983,0.0004016316,0.001034093,0.002519521,0.0001205819,0.001236117,0.000264234,0.1032868,0.5697783,0.2317995,0.004519256,0.08468011],"study_design_scores_gemma":[0.0002876425,0.002121834,0.002124339,0.000403617,0.0002487075,0.003027766,0.0003870258,0.3393089,0.3711094,0.1066002,0.174251,0.0001295503],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.3924907,0.2095883,0.30659,0.01327298,0.001087981,0.0004361138,0.001682644,0.001071248,0.07378],"genre_scores_gemma":[0.812517,0.1565482,0.02176624,0.001177806,0.0001612049,0.0001916249,0.0004166711,0.00004254664,0.007178606],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00165112,"threshold_uncertainty_score":0.005523503,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2028121694","doi":"10.2174/092986711797200435","title":"Alzheimer's Disease: Emerging Trends in Small Molecule Therapies","year":2011,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"University of Waterloo; Eisai","keywords":"Neuroscience; Amyloid (mycology); Drug discovery; Disease; Chemistry; Reactive oxygen species; Amyloid precursor protein; Amyloid precursor protein secretase; Alzheimer's disease; Dementia; Pharmacology; Medicine; Biochemistry; Psychology; Pathology","authors":[{"name":"Tarek Mohamed","is_ca":false},{"name":"Praveen P. N. Rao","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1506816093383987,"gpt":0.4008960099725205,"spread":0.2502144006341218,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001115551,0.00113782,0.001602864,0.00218926,0.0003603667,0.00123991,0.001018606,0.001515572,0.005034938],"category_scores_gemma":[0.0008506078,0.0003808852,0.0005406358,0.002596364,0.0007041681,0.002771383,0.000903121,0.002718476,0.003415402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008282066,"about_ca_system_score_gemma":0.0009134237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007231078,"about_ca_topic_score_gemma":0.001630284,"domain_scores_codex":[0.9996693,0.00005902589,0.00003540191,0.00005384763,0.0001498384,0.0000325888],"domain_scores_gemma":[0.9995652,0.0002213832,0.00004452538,0.00001535805,0.0001092104,0.00004427555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001175068,0.0002072706,0.0001044682,0.01153015,0.00008041311,0.0003009423,0.00008689905,0.0005925959,0.004239691,0.007810265,0.0322626,0.9426672],"study_design_scores_gemma":[0.00004538034,0.0001764186,0.0003823776,0.001893729,0.00006343376,0.0008718895,0.0000574972,0.0002025197,0.0006893807,0.003721657,0.9918771,0.00001863102],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001541735,0.9972825,0.0003533745,0.0004701545,0.0002973626,0.000008137132,0.00001170464,0.00001426904,0.001408371],"genre_scores_gemma":[0.0006062175,0.9971199,0.0005823999,0.0003337377,0.0003163411,0.000009501248,0.00001924753,0.000002474963,0.001010097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005034938,"threshold_uncertainty_score":0.01684362,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2170431584","doi":"10.2174/092986711798194388","title":"Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy","year":2011,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; St. Joseph's Hospital","funders":"Canadian Institutes of Health Research","keywords":"MAPK/ERK pathway; Kinase; Cancer research; Carcinogenesis; Cancer; DNA damage; Cell biology; Signal transduction; MEK inhibitor; Cancer cell; Cell growth; Biology; DNA; Biochemistry; Genetics","authors":[{"name":"Fengxiang Wei","is_ca":true},{"name":"Jenny Yan","is_ca":true},{"name":"Damu Tang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08065934151122492,"gpt":0.3626741349970199,"spread":0.2820147934857951,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004340695,0.0002417944,0.0002521831,0.0003281607,0.0001416001,0.0007286654,0.0001730041,0.0003238095,0.002060387],"category_scores_gemma":[0.0003681788,0.0000809691,0.0003232155,0.0002096083,0.0001786637,0.0003721605,0.0002640598,0.0009615262,0.0005674487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002698239,"about_ca_system_score_gemma":0.0002402481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002129738,"about_ca_topic_score_gemma":0.0008041031,"domain_scores_codex":[0.9998054,0.00005028468,0.00001731053,0.00002333821,0.00007041898,0.00003329001],"domain_scores_gemma":[0.9998739,0.00003629327,0.00003044987,0.000007040839,0.00003644856,0.0000158508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001359993,0.001068428,0.003630812,0.003348764,0.0002542838,0.00126124,0.0001691773,0.00192793,0.4114679,0.009381488,0.008932924,0.557197],"study_design_scores_gemma":[0.0006869489,0.005737547,0.02572029,0.0007515139,0.0008297537,0.008620889,0.0002477251,0.004659648,0.4922101,0.005757117,0.4547006,0.00007791395],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3704064,0.5591332,0.01105154,0.01063118,0.00188473,0.0002638389,0.000347598,0.0001721053,0.04610937],"genre_scores_gemma":[0.8049933,0.1725891,0.003548314,0.002214013,0.0007664278,0.0001180281,0.0002826211,0.00002701217,0.01546123],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002060387,"threshold_uncertainty_score":0.006892681,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2145826370","doi":"10.2174/092986713804806685","title":"A Metabolomic Study Reveals Novel Plasma Lyso-Gb3 Analogs As Fabry Disease Biomarkers","year":2012,"lang":"en","type":"article","venue":"Current Medicinal Chemistry","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Shire Human Genetic Therapies","keywords":"Fabry disease; Globotriaosylceramide; Sphingolipid; Alpha-galactosidase; Metabolomics; Chemistry; Internal medicine; Enzyme replacement therapy; Biomarker; Glycosphingolipid; Endocrinology; Disease; Medicine; Biochemistry; Chromatography","authors":[{"name":"Félix Dupont","is_ca":true},{"name":"René Gagnon","is_ca":false},{"name":"Michel Boutin","is_ca":false},{"name":"Christiane Auray‐Blais","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04745133862328876,"gpt":0.3613911981701345,"spread":0.3139398595468457,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001997327,0.0004038945,0.0004831435,0.0008046239,0.0002011232,0.0003848238,0.0001122872,0.0004681321,0.0007665882],"category_scores_gemma":[0.0003211887,0.0001120913,0.0002850914,0.0006187105,0.0001527246,0.0001727915,0.0002458999,0.0003226973,0.0001511883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001869543,"about_ca_system_score_gemma":0.0001251029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007349433,"about_ca_topic_score_gemma":0.0006020069,"domain_scores_codex":[0.9998882,0.00002098667,0.000005462413,0.00004180662,0.00002415666,0.00001936605],"domain_scores_gemma":[0.9998828,0.00002024098,0.00003763708,0.000007829975,0.00002616898,0.00002522666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004389683,0.0001803225,0.08764942,0.0001465226,0.0004545092,0.0007773227,0.0002342335,0.0005986484,0.8724619,0.0001934323,0.0004874096,0.03242674],"study_design_scores_gemma":[0.0001193994,0.00286834,0.7708461,0.00004314567,0.0006551134,0.004375121,0.00039317,0.01129177,0.2035094,0.0006882049,0.005123316,0.00008692878],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947624,0.001892315,0.001658732,0.0001047687,0.00001391181,0.00002232569,0.001150848,0.0000545546,0.0003402557],"genre_scores_gemma":[0.9953583,0.0006676342,0.002193006,0.0001605853,0.00002090594,0.00002863844,0.001040385,0.00001380534,0.0005167901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008046239,"threshold_uncertainty_score":0.00256443,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2622865031","doi":"10.2174/0929867324666170608111917","title":"Beneficial Effects of N-acetylcysteine and N-mercaptopropionylglycine on Ischemia Reperfusion Injury in the Heart","year":2018,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Acetylcysteine; Reperfusion injury; Antioxidant; Oxidative stress; Pharmacology; Medicine; Ischemia; Myocardial infarction; Cardiac function curve; Reactive oxygen species; Cardiology; Internal medicine; Chemistry; Biochemistry; Heart failure","authors":[{"name":"Monika Barteková","is_ca":false},{"name":"Miroslav Barančı́k","is_ca":false},{"name":"Kristína Ferenczyová","is_ca":false},{"name":"Naranjan S. Dhalla","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01947662434704978,"gpt":0.3366702579126657,"spread":0.317193633565616,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001597064,0.0004706093,0.0004122574,0.0003192267,0.0001406135,0.0001432009,0.0002710168,0.0003948098,0.001427665],"category_scores_gemma":[0.0001675191,0.00007583292,0.0002471509,0.000111482,0.0001935465,0.0002283407,0.000187391,0.0004321939,0.0001721638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000662992,"about_ca_system_score_gemma":0.0002119417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003502422,"about_ca_topic_score_gemma":0.0005489275,"domain_scores_codex":[0.9999486,0.00001445894,0.000007246103,0.000007443863,0.00001091635,0.00001123847],"domain_scores_gemma":[0.9998734,0.00001812579,0.00003018798,0.000009987844,0.0000202048,0.00004809923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01363345,0.001316411,0.0006951429,0.001231401,0.0001486212,0.0003760085,0.00007257536,0.0001779709,0.9512517,0.0001788767,0.0003639141,0.03055394],"study_design_scores_gemma":[0.002341408,0.0645392,0.02453758,0.0002222521,0.0008298221,0.00144416,0.000169025,0.001103867,0.8919864,0.0002543096,0.01253464,0.00003730692],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9742298,0.02289183,0.0004710739,0.0002232479,0.0002251068,0.00005586698,0.0001127813,0.00007096186,0.001719259],"genre_scores_gemma":[0.989468,0.007584734,0.001258177,0.0002195511,0.0001207976,0.00004187385,0.0001640167,0.0000120388,0.001130803],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001427665,"threshold_uncertainty_score":0.004775941,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2162123073","doi":"10.2174/092986707781389655","title":"Killer Beacons for Combined Cancer Imaging and Therapy","year":2007,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"National Cancer Institute; U.S. Department of Defense","keywords":"Cancer imaging; Cancer therapy; Beacon; Cancer; Medicine; Oncology; Internal medicine; Computer science","authors":[{"name":"Klara Stefflova","is_ca":false},{"name":"Juan Chen","is_ca":false},{"name":"Gang Zheng","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1622630085980611,"gpt":0.4852285545448488,"spread":0.3229655459467877,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004675474,0.0006189201,0.0005847717,0.0008308194,0.0001938901,0.0005988214,0.0005832735,0.0008660119,0.003368536],"category_scores_gemma":[0.0002957154,0.0002297638,0.000331865,0.000735097,0.0004485708,0.001013104,0.0007480312,0.001255272,0.001827453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000519169,"about_ca_system_score_gemma":0.0004571363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002661689,"about_ca_topic_score_gemma":0.0003464121,"domain_scores_codex":[0.9997669,0.00004025563,0.00001481193,0.00004985372,0.00009453314,0.0000337075],"domain_scores_gemma":[0.9999341,0.00001656833,0.00001351923,0.000005198749,0.00002047102,0.00001021731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001717955,0.000145952,0.0002121563,0.005109309,0.00006294667,0.0004715003,0.0001841591,0.001396668,0.3296061,0.0470913,0.01687452,0.5986736],"study_design_scores_gemma":[0.00004607924,0.0005523608,0.0004065424,0.0003702024,0.0000735333,0.001373938,0.00006414679,0.002188546,0.1622176,0.009471534,0.8231838,0.00005165096],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01569655,0.8375022,0.1088748,0.002322361,0.001796135,0.0001858818,0.0002972645,0.0008034608,0.03252128],"genre_scores_gemma":[0.1330233,0.7586214,0.06667317,0.00225215,0.0009596655,0.0004798829,0.0006288409,0.0001176443,0.03724401],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003368536,"threshold_uncertainty_score":0.01126885,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2134099579","doi":"10.2174/0929867023368872","title":"Drug Evolution: p-Aminobenzoic Acid as a Building Block","year":2002,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Moiety; Drug; Stereochemistry; Chemistry; Ring (chemistry); Amine gas treating; Combinatorial chemistry; Medicine; Pharmacology; Organic chemistry","authors":[{"name":"Alicja Kluczyk","is_ca":true},{"name":"T. Popek","is_ca":false},{"name":"Taira Kiyota","is_ca":false},{"name":"Pierre de Macédo","is_ca":false},{"name":"Piotr Stefanowicz","is_ca":false},{"name":"Carmen Lazar","is_ca":false},{"name":"Yasuo Konishi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02548674872559272,"gpt":0.3188993729671457,"spread":0.293412624241553,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002674721,0.0003202772,0.0003767819,0.0004217136,0.0001902046,0.0006147678,0.0003617016,0.0005299614,0.001746636],"category_scores_gemma":[0.0003247648,0.000189908,0.0003591863,0.0004956059,0.0003086325,0.0006747462,0.0004222319,0.000902515,0.001528396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005762376,"about_ca_system_score_gemma":0.0003322386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005391905,"about_ca_topic_score_gemma":0.0006048535,"domain_scores_codex":[0.9998054,0.00004031869,0.00001162888,0.00004366468,0.00007203401,0.00002698906],"domain_scores_gemma":[0.9999088,0.00002016794,0.00001889047,0.00000915873,0.00002439574,0.00001858135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002747519,0.000209471,0.001615597,0.002446748,0.0001358211,0.0008597071,0.0001335522,0.004447953,0.6128236,0.02571449,0.00620622,0.3451321],"study_design_scores_gemma":[0.00008166349,0.001714885,0.002336427,0.0002433132,0.0001752382,0.003639122,0.0000478262,0.005113997,0.3802266,0.006400577,0.5999667,0.00005366164],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2391099,0.5539441,0.1130679,0.004713625,0.001807117,0.0004217788,0.001122047,0.00113108,0.08468248],"genre_scores_gemma":[0.6329124,0.2697918,0.06548072,0.002008134,0.0004841887,0.0002740322,0.0011881,0.0001830863,0.02767763],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001746636,"threshold_uncertainty_score":0.005843043,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}