{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":80,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":80,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"39b5d41ae50a","filters":{"venue":"Current Topics in Medicinal Chemistry"}},"results":[{"id":"W2021349110","doi":"10.2174/1568026043451573","title":"Endogenous Opioids and Addiction to Alcohol and other Drugs of Abuse","year":2004,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":279,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre; Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Nucleus accumbens; Ventral tegmental area; Endogenous opioid; Opioid; Dopamine; Addiction; Brain stimulation reward; Pharmacology; Neuroscience; Mesolimbic pathway; Opioid peptide; Dopamine receptor; Psychology; Medicine; Receptor; Internal medicine; Dopaminergic","authors":[{"name":"Christina Gianoulakis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.106516973633144,"gpt":0.3589749994839588,"spread":0.2524580258508149,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000199329,0.0006043271,0.0007917598,0.001207027,0.0003334323,0.0006032188,0.0005037676,0.0008931596,0.004697246],"category_scores_gemma":[0.0002082559,0.0001465469,0.0001956909,0.001750864,0.0004015713,0.0007023474,0.0004536661,0.0007400429,0.003054542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004480921,"about_ca_system_score_gemma":0.0007673067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001419797,"about_ca_topic_score_gemma":0.002944276,"domain_scores_codex":[0.9998895,0.00001962312,0.00001265362,0.00001888548,0.00004546623,0.00001395228],"domain_scores_gemma":[0.9999354,0.00001799115,0.00001253678,0.000003073905,0.00001980243,0.00001118256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004725707,0.0000755101,0.0004525657,0.004879185,0.00003913704,0.0005620344,0.00008980012,0.0001492617,0.002296087,0.003332448,0.01885528,0.9692215],"study_design_scores_gemma":[0.000009838681,0.00006986533,0.002764405,0.001196562,0.0000336822,0.002871481,0.0001024422,0.00003633377,0.0004747027,0.002136444,0.9902945,0.00000974922],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002606768,0.9968756,0.0000920895,0.0001643513,0.0001639613,0.000003923487,0.000009434902,0.000005264627,0.002424655],"genre_scores_gemma":[0.00134548,0.9959645,0.000116262,0.000122803,0.0001687555,0.000005836811,0.00001765555,8.229609e-7,0.002257867],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004697246,"threshold_uncertainty_score":0.01571381,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1982873906","doi":"10.2174/1568026013395605","title":"Multidrug Efflux in Pseudomonas aeruginosa Components, Mechanisms and Clinical Significance","year":2001,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":269,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"Cystic Fibrosis Canada; Ministry of Education, Culture, Sports, Science and Technology; Cystic Fibrosis Foundation","keywords":"Efflux; Pseudomonas aeruginosa; Multiple drug resistance; Biology; Periplasmic space; Microbiology; Bacterial outer membrane; Antimicrobial; Antiporter; Antibiotic resistance; Quorum sensing; Homoserine; Drug resistance; Bacteria; Biochemistry; Antibiotics; Genetics; Membrane; Escherichia coli; Gene; Virulence","authors":[{"name":"Keith Poole","is_ca":true},{"name":"Ramakrishnan Srikumar","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05694919784018947,"gpt":0.3785586081124495,"spread":0.32160941027226,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004397966,0.0002619704,0.0002982341,0.0004828097,0.0003289739,0.001111751,0.0002860122,0.0007690474,0.001276121],"category_scores_gemma":[0.0008415238,0.0001165846,0.0001372783,0.000570266,0.0007190731,0.0006674627,0.0004070041,0.00082017,0.0003953493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000655111,"about_ca_system_score_gemma":0.000656462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007609208,"about_ca_topic_score_gemma":0.0003971355,"domain_scores_codex":[0.9998214,0.00004563994,0.00001886761,0.00002312527,0.00005045572,0.00004068496],"domain_scores_gemma":[0.9997457,0.00007489148,0.00005765355,0.00001567711,0.00005867338,0.00004746964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002016049,0.0006096278,0.07683135,0.004710309,0.00006885838,0.01605224,0.0008915303,0.0006551326,0.3119331,0.03840185,0.01242991,0.5354],"study_design_scores_gemma":[0.0003155522,0.003654078,0.3888456,0.001310423,0.0002443506,0.1158018,0.001606261,0.002693047,0.06625567,0.03150338,0.3875984,0.0001713572],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2398281,0.7190063,0.003842651,0.01944,0.0003067018,0.0001276596,0.0003154077,0.0001864688,0.01694672],"genre_scores_gemma":[0.8734746,0.119119,0.001402533,0.001124762,0.0006869105,0.00008610223,0.0002417836,0.00001484203,0.003849467],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001276121,"threshold_uncertainty_score":0.004753232,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2558057290","doi":"10.2174/1568026617666161116143440","title":"Bioinformatics and Drug Discovery","year":2017,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":245,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"","keywords":"Drug discovery; Computational biology; Drug repositioning; Computer science; Profiling (computer programming); Proteomics; Structural genomics; Identification (biology); Virtual screening; Drug; Bioinformatics; Data science; Biology; Protein structure; Gene; Pharmacology; Genetics","authors":[{"name":"Xuhua Xia","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06991515649462367,"gpt":0.3936113403846406,"spread":0.3236961838900169,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003169804,0.00155336,0.002208199,0.003354714,0.0006013302,0.004769318,0.003227708,0.002870542,0.01494032],"category_scores_gemma":[0.005040191,0.000562844,0.00105131,0.004956605,0.002522942,0.004517439,0.002480779,0.006037621,0.01480746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002603307,"about_ca_system_score_gemma":0.003942765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001679798,"about_ca_topic_score_gemma":0.001592382,"domain_scores_codex":[0.9977259,0.0006671628,0.0001902195,0.0002993099,0.0009806807,0.0001368435],"domain_scores_gemma":[0.9975107,0.001390261,0.000159571,0.0002068426,0.00052238,0.0002101911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004252977,0.00007858522,0.0002746334,0.005816305,0.0001530573,0.0001844684,0.00009364623,0.001171115,0.0006214489,0.07412495,0.1479237,0.7695157],"study_design_scores_gemma":[0.00001430148,0.00003120652,0.0001470587,0.00122624,0.00002189827,0.0003466032,0.00003182778,0.0002487976,0.0001782601,0.02489449,0.972845,0.00001441725],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003177143,0.9381319,0.0114635,0.01693415,0.003344653,0.0001325691,0.0004277798,0.0003281159,0.02891978],"genre_scores_gemma":[0.003856454,0.9659312,0.009088724,0.008586979,0.00260793,0.0001460824,0.0006294344,0.00006396462,0.00908926],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01494032,"threshold_uncertainty_score":0.04998034,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2083174947","doi":"10.2174/156802608785848987","title":"Recent Trends in Glycodendrimer Syntheses and Applications","year":2008,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Glycoconjugate; Glycan; Avidity; Chemistry; Computational biology; Glycobiology; Bacterial adhesin; Glycopeptide; Click chemistry; Mechanism (biology); Drug discovery; Dendrimer; Biology; Cell biology; Biochemistry; Combinatorial chemistry; Antigen; Glycoprotein; Virulence; Gene; Immunology","authors":[{"name":"Yoann M. Chabre","is_ca":true},{"name":"René Roy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07631292395456554,"gpt":0.4002602200124858,"spread":0.3239472960579203,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007176716,0.0008925994,0.0007575164,0.001322224,0.0002291254,0.0007240067,0.0007175783,0.0006282344,0.002988815],"category_scores_gemma":[0.0005274208,0.0004373692,0.0003859565,0.001925084,0.0004385952,0.001373689,0.0004710071,0.001056352,0.002106226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006574628,"about_ca_system_score_gemma":0.0005274892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004409126,"about_ca_topic_score_gemma":0.0005685759,"domain_scores_codex":[0.9998024,0.00002849316,0.00002258371,0.00005037943,0.00007743111,0.00001879865],"domain_scores_gemma":[0.9997571,0.00009315223,0.00005814826,0.00001611396,0.00005024989,0.00002522709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001626135,0.0001740334,0.0002236876,0.009647123,0.00005078324,0.0003219928,0.000116906,0.002531026,0.06137375,0.007143809,0.00594281,0.9123114],"study_design_scores_gemma":[0.0000438452,0.0004918837,0.0007800437,0.000722999,0.00009871053,0.001772128,0.00008202362,0.00112225,0.0498369,0.003320473,0.9416871,0.000041623],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004744789,0.9840292,0.004751599,0.0003800821,0.0002454066,0.00002655091,0.00004478423,0.00005967311,0.005717926],"genre_scores_gemma":[0.009718401,0.9828451,0.004248533,0.0002895303,0.0002314911,0.00002770772,0.00008904381,0.00001082939,0.00253943],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002988815,"threshold_uncertainty_score":0.00999856,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2124252984","doi":"10.2174/1568026054367629","title":"Role of Cation-Chloride-Cotransporters (CCC) in Pain and Hyperalgesia","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":197,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; McGill University","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cotransporter; GABAergic; Inhibitory postsynaptic potential; Chemistry; Nociception; Neuroscience; Depolarization; Nociceptor; Spinal cord; Glycine receptor; Hyperalgesia; Pharmacology; Biophysics; Cell biology; Biochemistry; Medicine; Biology; Glycine; Receptor; Sodium","authors":[{"name":"Theodore J. Price","is_ca":true},{"name":"Fernando Cerveró","is_ca":true},{"name":"Yves De Koninck","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0385513509255555,"gpt":0.3408740506435239,"spread":0.3023226997179684,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003021625,0.0006731696,0.0009230368,0.001176658,0.0002823028,0.0006516591,0.0005569062,0.001002154,0.002542856],"category_scores_gemma":[0.0002330092,0.0001783844,0.0002548919,0.001292566,0.0003880345,0.0009375666,0.0004001633,0.0008024402,0.002440352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000447208,"about_ca_system_score_gemma":0.0006319363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007813404,"about_ca_topic_score_gemma":0.001318184,"domain_scores_codex":[0.999891,0.00001663715,0.0000149083,0.0000182181,0.00004366017,0.00001550793],"domain_scores_gemma":[0.9998978,0.00002903276,0.00001904411,0.000003386031,0.00003396414,0.00001664387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001428432,0.0000926873,0.0003551682,0.00892162,0.00007096626,0.0006224046,0.00006328892,0.0004609765,0.0124616,0.003982681,0.01475416,0.9580718],"study_design_scores_gemma":[0.00004228092,0.000193114,0.002124749,0.001077212,0.0001012757,0.003369134,0.00009269219,0.0002363599,0.004017739,0.00313166,0.9855899,0.00002390907],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003547798,0.99787,0.0002392304,0.000160727,0.0001719794,0.000004552022,0.000008705181,0.00001034515,0.001179731],"genre_scores_gemma":[0.003145633,0.9947896,0.0003057436,0.0001768042,0.0001700744,0.000006294852,0.00002030418,0.000001383006,0.001384104],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002542856,"threshold_uncertainty_score":0.008506715,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2073025150","doi":"10.2174/156802611795347582","title":"Molecular Biology of Nucleoside Transporters and their Distributions and Functions in the Brain","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta; University of Manitoba","funders":"Canadian Institutes of Health Research; British Heart Foundation; Wellcome Trust","keywords":"Nucleoside; Purine; Transporter; Biology; Nucleoside transporter; Adenosine; Nucleotide; Biochemistry; Function (biology); Cell biology; Gene; Enzyme","authors":[{"name":"Fiona E. Parkinson","is_ca":true},{"name":"Vijaya L. Damaraju","is_ca":false},{"name":"Kathryn Graham","is_ca":false},{"name":"Sylvia Y.M. Yao","is_ca":false},{"name":"Stephen A. Baldwin","is_ca":false},{"name":"Carol E. Cass","is_ca":false},{"name":"James D. Young","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03433079696973027,"gpt":0.3262579335307929,"spread":0.2919271365610626,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001990707,0.0004312708,0.0005215878,0.0007490923,0.000232491,0.0009644351,0.0004021546,0.0007562148,0.001031058],"category_scores_gemma":[0.0001335794,0.0002064849,0.0003564492,0.0006002932,0.0003063143,0.001418222,0.0002379057,0.0008865462,0.0006345834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008144539,"about_ca_system_score_gemma":0.0005721805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009796633,"about_ca_topic_score_gemma":0.001133125,"domain_scores_codex":[0.999915,0.00001063444,0.00000945497,0.00002458425,0.00002425149,0.00001611392],"domain_scores_gemma":[0.999947,0.000009812885,0.00001253164,0.000001595545,0.00001872676,0.00001034849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004378241,0.000117544,0.002029381,0.006322884,0.0001869386,0.002137042,0.0004123467,0.001658651,0.5059958,0.04583422,0.01300739,0.42186],"study_design_scores_gemma":[0.00004984269,0.0006688164,0.01905254,0.001220422,0.0004051913,0.01450766,0.0005172328,0.004353608,0.1531746,0.03167886,0.774218,0.0001533247],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01696279,0.969302,0.006668207,0.001251972,0.0002155981,0.00002621735,0.0001698186,0.0001074019,0.005296011],"genre_scores_gemma":[0.04513944,0.9455753,0.0039334,0.0003916953,0.0003690553,0.00004797767,0.0003219152,0.00001424113,0.004206915],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001031058,"threshold_uncertainty_score":0.005909324,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2041787141","doi":"10.2174/1568026013395623","title":"Structural Biology of Bacterial Iron Uptake Systems","year":2001,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Periplasmic space; Bacterial outer membrane; Siderophore; Biochemistry; Biology; Escherichia coli; Bacteria; Serratia marcescens; Membrane protein; Iron-binding proteins; Membrane transport protein; Transport protein; Heme; Inner membrane; Microbiology; Chemistry; Transferrin; Membrane; Gene","authors":[{"name":"Teresa E. Clarke","is_ca":true},{"name":"Leslie W. Tari","is_ca":false},{"name":"Hans J. Vogel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03907339219779003,"gpt":0.3328457818495502,"spread":0.2937723896517602,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001959981,0.0003940507,0.0003304418,0.000323148,0.0008288836,0.0007925772,0.0006187025,0.0009054233,0.00134699],"category_scores_gemma":[0.0003860448,0.0002866775,0.0001968627,0.0002709151,0.0005033248,0.0006778102,0.0004450856,0.000901408,0.001218318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001176296,"about_ca_system_score_gemma":0.0003756094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007987497,"about_ca_topic_score_gemma":0.0003800682,"domain_scores_codex":[0.9998306,0.00002742345,0.000008830159,0.00003253009,0.00006343126,0.00003722862],"domain_scores_gemma":[0.9998522,0.00002369142,0.00002145418,0.00001242029,0.00005134364,0.00003882447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001429192,0.0001253342,0.001427816,0.0007374528,0.00003183089,0.0003923559,0.0004835538,0.00958214,0.9035717,0.05531733,0.003284792,0.02490275],"study_design_scores_gemma":[0.0001155436,0.001195464,0.01101282,0.0002250231,0.00005524946,0.0028807,0.001081596,0.09974026,0.5558109,0.1056596,0.2220715,0.000151342],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8733045,0.0356048,0.0412102,0.006344645,0.0006118122,0.0001179237,0.0005834452,0.0008868391,0.04133568],"genre_scores_gemma":[0.9765967,0.006625746,0.008273057,0.0004867258,0.00009335248,0.00006985027,0.001012266,0.00005596378,0.00678631],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00134699,"threshold_uncertainty_score":0.00853467,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1992723722","doi":"10.2174/156802605774642999","title":"C-Glycosides and Aza-C-Glycosides as Potential Glycosidase and Glycosyltransferase Inhibitors","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":161,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"National Research Council Canada","keywords":"Glycoside hydrolase; Glycosyltransferase; Glycoside; Chemistry; Glycosylation; Anomer; Enzyme; Stereochemistry; Biochemistry","authors":[{"name":"Wei Zou","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02843347442739292,"gpt":0.3189391996700521,"spread":0.2905057252426592,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001787481,0.0006547528,0.0004990681,0.0008708697,0.0001461816,0.0003717371,0.000361182,0.0005062198,0.002339468],"category_scores_gemma":[0.000115714,0.0001450494,0.0001918851,0.0008322614,0.0001940297,0.0005608508,0.0002260353,0.0006858286,0.001826514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003543781,"about_ca_system_score_gemma":0.0002596556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00042441,"about_ca_topic_score_gemma":0.0009564689,"domain_scores_codex":[0.9999183,0.00001137683,0.000006984619,0.00001337712,0.00003913719,0.00001074176],"domain_scores_gemma":[0.9999678,0.000006998534,0.000006339493,0.000001625851,0.00001060573,0.000006648549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002019031,0.0002489338,0.0002345315,0.004912618,0.00005687861,0.0006893686,0.00007115863,0.001467485,0.08410871,0.01149122,0.01401761,0.8824996],"study_design_scores_gemma":[0.00006084697,0.0004130835,0.0009551313,0.0004374271,0.00005441128,0.002029,0.00003768902,0.0004991018,0.03263511,0.001848495,0.9610069,0.00002289358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004253936,0.9842706,0.001621264,0.0002392668,0.0002923052,0.00002705549,0.00004671632,0.00003608043,0.009212619],"genre_scores_gemma":[0.01903673,0.9671788,0.002411019,0.0003090939,0.0002074312,0.00003357227,0.0001091886,0.000005217594,0.01070896],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002339468,"threshold_uncertainty_score":0.007826328,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2089063761","doi":"10.2174/156802605774643015","title":"Bioactive C-Glycosides from Bacterial Secondary Metabolism","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":143,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Glycosidic bond; Biosynthesis; Glycoside; Glycosyltransferase; Streptomyces; Bacteria; Chemistry; Biochemistry; Computational biology; Biology; Gene; Stereochemistry; Genetics; Enzyme","authors":[{"name":"Philip G. Hultin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05249884151208032,"gpt":0.3322579711893383,"spread":0.2797591296772579,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001384403,0.0007460521,0.0005731048,0.001058426,0.0002413239,0.0006492801,0.0002875411,0.0004067369,0.00358355],"category_scores_gemma":[0.0001257007,0.0001507539,0.0001923083,0.001252699,0.0002143481,0.0006019782,0.0003459194,0.0005995759,0.005181576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004113677,"about_ca_system_score_gemma":0.0004788186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003328755,"about_ca_topic_score_gemma":0.0006069092,"domain_scores_codex":[0.9999402,0.000005853771,0.000005206312,0.00001140172,0.0000297742,0.000007573305],"domain_scores_gemma":[0.9999639,0.000006972989,0.000006615848,0.000002416454,0.00001150825,0.000008609951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006484926,0.00006057756,0.0001504032,0.005303226,0.00002341275,0.0004544008,0.00005546904,0.0005716867,0.07003222,0.006808054,0.00773768,0.9087381],"study_design_scores_gemma":[0.00001512525,0.0001647293,0.001031452,0.0007628766,0.00002893905,0.002012516,0.00005088949,0.000146712,0.02716147,0.003172569,0.9654331,0.00001956337],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004354117,0.9667237,0.002832591,0.0002949661,0.0003960223,0.00003791376,0.0001199126,0.00007260463,0.02516811],"genre_scores_gemma":[0.01432685,0.9744055,0.002073527,0.0002055918,0.0001902301,0.0000259175,0.0002160592,0.000008530351,0.0085479],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00358355,"threshold_uncertainty_score":0.01198816,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011386695","doi":"10.2174/156802611796575902","title":"Sterol 14alpha-Demethylase (CYP51) as a Therapeutic Target for Human Trypanosomiasis and Leishmaniasis","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Leishmaniasis; Sterol; Demethylase; Virology; Chemistry; Pharmacology; Medicine; Immunology; Biochemistry; Cholesterol","authors":[{"name":"Galina I. Lepesheva","is_ca":false},{"name":"Michael R. Waterman","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1626570078089472,"gpt":0.4490980134472805,"spread":0.2864410056383333,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002071536,0.0005479254,0.0008405153,0.00130548,0.0002347499,0.000522495,0.0003742986,0.000657143,0.004218736],"category_scores_gemma":[0.0002059444,0.0001636732,0.0002507085,0.001565663,0.0002401448,0.0007025834,0.0003396897,0.0008442659,0.002932495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003533195,"about_ca_system_score_gemma":0.0005404627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006066904,"about_ca_topic_score_gemma":0.001352314,"domain_scores_codex":[0.9999248,0.00001177498,0.000008590996,0.00001494825,0.00003048365,0.00000940159],"domain_scores_gemma":[0.999936,0.00001958992,0.00001123786,0.000002844019,0.00002090769,0.000009523922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009415179,0.0001011625,0.000171283,0.009439874,0.00005833098,0.000409707,0.00005358748,0.0003629178,0.0103898,0.00301693,0.02430447,0.9515978],"study_design_scores_gemma":[0.0000294401,0.0001683536,0.001043762,0.0009376304,0.00006793243,0.001899085,0.00004800914,0.0001210041,0.001946007,0.001173626,0.9925514,0.00001373038],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006018973,0.9952422,0.0003063366,0.000283511,0.0002126443,0.00001051527,0.00003362148,0.00001972724,0.003289499],"genre_scores_gemma":[0.003051069,0.9933363,0.0004766691,0.0002087459,0.0001599918,0.000009515183,0.00006495449,0.000002652159,0.002690185],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004218736,"threshold_uncertainty_score":0.01411307,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4238309752","doi":"10.2174/156802609789630956","title":"Endogenous Opioids and Addiction to Alcohol and other Drugs of Abuse","year":2009,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":114,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Nucleus accumbens; Endogenous opioid; Ventral tegmental area; Opioid; Dopamine; Addiction; Brain stimulation reward; Pharmacology; Neuroscience; Mesolimbic pathway; Opioid peptide; Dopamine receptor; Medicine; Psychology; Receptor; Internal medicine; Dopaminergic","authors":[{"name":"Christina Gianoulakis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05165786898545973,"gpt":0.308321307895854,"spread":0.2566634389103943,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001978555,0.0002342611,0.0002749533,0.0005395454,0.0003535989,0.0004502008,0.0001929391,0.0005064925,0.004157296],"category_scores_gemma":[0.0003483928,0.00006905181,0.0001459771,0.0007287365,0.0004135035,0.0002611515,0.0004671398,0.0006002537,0.0005833421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004230005,"about_ca_system_score_gemma":0.0005420739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002576474,"about_ca_topic_score_gemma":0.005136854,"domain_scores_codex":[0.9998657,0.00003832443,0.00001242021,0.00001422261,0.00004647705,0.00002289936],"domain_scores_gemma":[0.9998659,0.00002505131,0.00005014395,0.000004892707,0.00002507751,0.00002889177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0005287715,0.000615477,0.04338019,0.00360705,0.0002374779,0.006084489,0.001016299,0.0003404251,0.01689479,0.04046717,0.0233108,0.863517],"study_design_scores_gemma":[0.00005101648,0.0006736701,0.3127605,0.001438499,0.0001899683,0.01573674,0.0009612033,0.0002997202,0.003192908,0.02612103,0.6385272,0.0000475633],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04181401,0.9320732,0.0004670091,0.003985779,0.0004718539,0.00002662982,0.0001629642,0.0000162715,0.02098238],"genre_scores_gemma":[0.1663859,0.8165352,0.0005232833,0.001220279,0.0008413318,0.00003402637,0.0001839273,0.000003213967,0.01427281],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004157296,"threshold_uncertainty_score":0.01390755,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2890191325","doi":"10.2174/1568026618666181115093136","title":"Anxiety Disorders: Sex Differences in Serotonin and Tryptophan Metabolism","year":2018,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Serotonin transporter; Anxiety; Serotonin; Anxiogenic; Kynurenine; Serotonin Plasma Membrane Transport Proteins; Medicine; Endocrinology; Internal medicine; Psychology; Tryptophan; Biology; Psychiatry; Receptor; Anxiolytic; Genetics","authors":[{"name":"Tanya Songtachalert","is_ca":false},{"name":"Chutima Roomruangwong","is_ca":false},{"name":"André F. Carvalho","is_ca":true},{"name":"Michel Bourin","is_ca":false},{"name":"Michaël Maes","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06359803012698073,"gpt":0.3413592930979954,"spread":0.2777612629710147,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003553283,0.0003307447,0.0008793423,0.001112855,0.0001684424,0.0008979415,0.0002533012,0.0004691064,0.004402853],"category_scores_gemma":[0.001036833,0.0001217287,0.0006767903,0.001497162,0.000259423,0.0005527255,0.0003819721,0.0003411621,0.0004383643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000380828,"about_ca_system_score_gemma":0.0009191998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002173697,"about_ca_topic_score_gemma":0.002480238,"domain_scores_codex":[0.9997587,0.00006838754,0.00005155354,0.00004587957,0.00005308204,0.0000223935],"domain_scores_gemma":[0.9995061,0.0002749705,0.0001503648,0.000006479439,0.00004878827,0.0000133745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006185852,0.0000419837,0.00821568,0.1470118,0.001199194,0.001300394,0.0006093346,0.000197429,0.002799828,0.003119821,0.01750331,0.8173827],"study_design_scores_gemma":[0.0001738975,0.0008875778,0.1032349,0.1227123,0.007186041,0.02108653,0.001747358,0.0002080007,0.002400432,0.006268946,0.7339665,0.0001275088],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00167744,0.996816,0.00006709968,0.0004405768,0.0001124195,0.00000768678,0.0001627882,0.000003649958,0.0007123894],"genre_scores_gemma":[0.01623768,0.9824598,0.0001584088,0.0003585927,0.0002247569,0.00001723804,0.0001413315,0.000001588181,0.0004006904],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004402853,"threshold_uncertainty_score":0.01472896,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1972833860","doi":"10.2174/1568026615666150225104543","title":"Anesthetics Act in Quantum Channels in Brain Microtubules to Prevent Consciousness","year":2015,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Anesthetic; Chemistry; Microtubule; Biophysics; Tubulin; Cell biology; Biology; Medicine; Anesthesia","authors":[{"name":"Travis J. A. Craddock","is_ca":false},{"name":"Stuart R. Hameroff","is_ca":false},{"name":"Ahmed T. Ayoub","is_ca":true},{"name":"Mariusz Kłobukowski","is_ca":true},{"name":"Jack A. Tuszyński","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08915941179643098,"gpt":0.3810980718300935,"spread":0.2919386600336625,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001499078,0.0002284575,0.000179051,0.0001818944,0.000501994,0.0004116163,0.00032957,0.0005825684,0.002078418],"category_scores_gemma":[0.0002607651,0.0001459775,0.0003131561,0.0001238185,0.0006153249,0.001098588,0.00038996,0.0006282245,0.000449795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004051012,"about_ca_system_score_gemma":0.0003358769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007224731,"about_ca_topic_score_gemma":0.0007812785,"domain_scores_codex":[0.999915,0.00001331559,0.000005000193,0.00001716749,0.00002559461,0.00002392166],"domain_scores_gemma":[0.9998925,0.00002608793,0.0000481538,0.000008893831,0.00001242742,0.0000119896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002045717,0.0000742155,0.0008752151,0.0002934196,0.00002657321,0.0003297779,0.0001452667,0.001380691,0.9576743,0.02331509,0.0006883453,0.01499253],"study_design_scores_gemma":[0.00006418512,0.0007419714,0.003512342,0.00004221778,0.0000550839,0.0005727445,0.0001850342,0.005188091,0.9665462,0.006297538,0.01677069,0.0000239717],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9447258,0.01457166,0.0266601,0.001978905,0.000271858,0.00006401087,0.0001301969,0.0004003907,0.01119717],"genre_scores_gemma":[0.9821468,0.008651987,0.005356926,0.0004456735,0.00006449864,0.00003166925,0.00005726216,0.00002454247,0.003220689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002078418,"threshold_uncertainty_score":0.006953001,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2006724497","doi":"10.2174/1568026033452320","title":"Protein Tyrosine Phosphatase &amp;#945; (PTP&amp;#945;): A Src Family Kinase Activator and Mediator of Multiple Biological Effects","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"","keywords":"Proto-oncogene tyrosine-protein kinase Src; Protein tyrosine phosphatase; Cell biology; Activator (genetics); Kinase; Tyrosine-protein kinase CSK; Phosphatase; Biology; Tyrosine kinase; Signal transduction; Regulator; Mediator; SH3 domain; Chemistry; Phosphorylation; Biochemistry; Receptor; Gene","authors":[{"name":"Catherine J. Pallen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04988627676694708,"gpt":0.3344775355598993,"spread":0.2845912587929523,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002334511,0.0006555923,0.0006562036,0.00103522,0.0002459107,0.0006101839,0.0004133388,0.000654891,0.003334916],"category_scores_gemma":[0.0001943043,0.0001401088,0.0001739286,0.001407697,0.0002635422,0.000936298,0.0003394422,0.0006874556,0.004508776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003911759,"about_ca_system_score_gemma":0.0004864568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004793459,"about_ca_topic_score_gemma":0.001030744,"domain_scores_codex":[0.9999222,0.000008141974,0.00000806252,0.00001606929,0.00003596188,0.000009479099],"domain_scores_gemma":[0.9999346,0.00001657896,0.00001266525,0.000002376669,0.00001805322,0.00001585394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006574947,0.00005333402,0.0001742808,0.003947991,0.0000323424,0.0003238169,0.00004218618,0.0001941808,0.006418013,0.002048102,0.02507466,0.9616253],"study_design_scores_gemma":[0.00001830456,0.0001016103,0.0007845015,0.0004635529,0.00004012353,0.002491584,0.00004590072,0.00006216144,0.001524377,0.0009465232,0.9935125,0.000008889931],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000603415,0.9944038,0.0004219754,0.0002626987,0.0003346125,0.000006790598,0.00001983462,0.00002253605,0.003924355],"genre_scores_gemma":[0.002758221,0.990429,0.0005671611,0.0002913265,0.0002972206,0.00001072419,0.0000695756,0.000003019792,0.005573681],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003334916,"threshold_uncertainty_score":0.01115638,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2105395808","doi":"10.2174/1568026054367638","title":"Cellular Signalling Pathways of Spinal Pain Neuroplasticity as Targets for Analgesic Development","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroscience; Ionotropic effect; Glutamatergic; Kainate receptor; AMPA receptor; NMDA receptor; Nociception; Glutamate receptor; Neurotransmission; Microglia; Synaptic plasticity; Biology; Receptor; Medicine; Internal medicine; Inflammation","authors":[{"name":"Michael Salter","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09331946387860961,"gpt":0.3626373062188595,"spread":0.2693178423402499,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004163218,0.0009467834,0.001393427,0.001658633,0.0003148384,0.000905142,0.001085013,0.001052004,0.003638907],"category_scores_gemma":[0.0002505312,0.0002533143,0.0003444028,0.001670949,0.0005978907,0.001339485,0.0004378796,0.001256534,0.003360503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008059676,"about_ca_system_score_gemma":0.000696161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006440483,"about_ca_topic_score_gemma":0.001002362,"domain_scores_codex":[0.9998755,0.00002371264,0.00001417387,0.00001854131,0.00005060901,0.00001731162],"domain_scores_gemma":[0.9999187,0.00002714158,0.00001322331,0.000003880049,0.00002638245,0.00001066965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001588951,0.0001620488,0.0001630581,0.01407322,0.00006016213,0.0007844545,0.0001278799,0.0008851078,0.01900112,0.01163506,0.01718727,0.9357616],"study_design_scores_gemma":[0.00004128566,0.0001429247,0.001015749,0.001987146,0.00006721407,0.001690509,0.00009935151,0.0001814806,0.00367912,0.00546001,0.9856135,0.00002158249],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003441662,0.996524,0.0003965853,0.0002057686,0.0001591056,0.00001009172,0.00001400779,0.0000133854,0.002332847],"genre_scores_gemma":[0.001649719,0.996237,0.0004700712,0.0001456182,0.0001112963,0.00001394621,0.00002615565,0.000001335478,0.001344839],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003638907,"threshold_uncertainty_score":0.0121733,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2079295573","doi":"10.2174/156802610793176648","title":"Strategies for the Discovery and Advancement of Novel Cationic Antimicrobial Peptides","year":2010,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":81,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Antimicrobial peptides; Antimicrobial; In silico; Peptide; Biology; Cathelicidin; Computational biology; Microbiology; Biochemistry","authors":[{"name":"Erik B. Hadley","is_ca":false},{"name":"Robert E. W. Hancock","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04742005158298743,"gpt":0.3420176079674309,"spread":0.2945975563844435,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001375442,0.0007907068,0.000741117,0.0007002762,0.000213555,0.001224792,0.0005222111,0.0007109183,0.00159521],"category_scores_gemma":[0.0007839421,0.000342593,0.0007171739,0.0005030708,0.0005831565,0.001291789,0.0008294133,0.001819099,0.0008160617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006297124,"about_ca_system_score_gemma":0.0007073447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002418389,"about_ca_topic_score_gemma":0.0003545568,"domain_scores_codex":[0.9995465,0.0001188697,0.00003539827,0.00007312879,0.0001795279,0.00004658502],"domain_scores_gemma":[0.9997397,0.00008489502,0.00005523287,0.00002129921,0.0000700192,0.00002885396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001799123,0.000261092,0.0005334684,0.002136291,0.00006676924,0.0003490315,0.0001444505,0.005344049,0.8751003,0.01038184,0.001109643,0.1043932],"study_design_scores_gemma":[0.0002450888,0.005069568,0.001374499,0.0005634809,0.0001987997,0.001677821,0.0002252219,0.01694695,0.8104123,0.009932891,0.1532504,0.0001029995],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.248735,0.2233851,0.5002543,0.006300684,0.0008369736,0.001573419,0.0007858029,0.0007947485,0.01733393],"genre_scores_gemma":[0.5176576,0.1911538,0.2763262,0.002952569,0.0003063197,0.001167121,0.001075745,0.000100057,0.009260491],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00159521,"threshold_uncertainty_score":0.007274091,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2956753841","doi":"10.2174/1568026619666190709092647","title":"Targeting the PAC1 Receptor for Neurological and Metabolic Disorders","year":2019,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":72,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Army Research Office; National Institute of General Medical Sciences; National Institutes of Health","keywords":"G protein-coupled receptor; Signal transduction; Neuroscience; Neurodegeneration; Nervous system; Receptor; Adenylyl cyclase; Cell biology; Biology; Medicine; Internal medicine; Disease","authors":[{"name":"Chenyi Liao","is_ca":false},{"name":"Mathilde Poujol de Molliens","is_ca":true},{"name":"Severin T. Schneebeli","is_ca":false},{"name":"Matthias Brewer","is_ca":false},{"name":"Gaojie Song","is_ca":false},{"name":"David Chatenet","is_ca":true},{"name":"Karen M. Braas","is_ca":false},{"name":"Víctor May","is_ca":false},{"name":"Jianing Li","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1005287857558672,"gpt":0.3679467762210247,"spread":0.2674179904651576,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001548744,0.000535571,0.0004612957,0.0004718636,0.0001631472,0.0005330893,0.0003977165,0.0005637232,0.003239062],"category_scores_gemma":[0.0001663031,0.0001102765,0.0003377416,0.000310292,0.0001652261,0.0004925146,0.0003488569,0.001172682,0.002086093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003250907,"about_ca_system_score_gemma":0.000307849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003002394,"about_ca_topic_score_gemma":0.000513921,"domain_scores_codex":[0.9999098,0.00001203946,0.000010548,0.00001655197,0.00003201085,0.00001903101],"domain_scores_gemma":[0.9999651,0.000007133649,0.000009815083,0.000001439539,0.000009918977,0.000006711113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003248985,0.0001664385,0.0003730862,0.007578712,0.00009923767,0.001752994,0.000133237,0.0005500801,0.2517534,0.009910697,0.0344351,0.6929222],"study_design_scores_gemma":[0.00006401561,0.0004394636,0.001496296,0.0005046147,0.0001277225,0.006096249,0.00005097611,0.0005605856,0.0337068,0.001820676,0.9550934,0.0000391774],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006548455,0.9770864,0.004223684,0.001357244,0.0007118724,0.00006711881,0.0002214563,0.0001293585,0.009654413],"genre_scores_gemma":[0.02802492,0.9551536,0.004076513,0.001369709,0.0007045322,0.0001121765,0.0005871521,0.00002187837,0.009949426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003239062,"threshold_uncertainty_score":0.01083577,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109893892","doi":"10.2174/1568026033392499","title":"Traditionally-Used Antimalarials from the Meliaceae","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Phytochemical compounds biological activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"","keywords":"Meliaceae; Azadirachta; Phytomedicine; Traditional medicine; Limonoid; Biology; Melia azedarach; Medicinal plants; Pharmacology; Botany; Medicine","authors":[{"name":"Samia S. Omar","is_ca":true},{"name":"J. Zhang","is_ca":true},{"name":"Shawna L. MacKinnon","is_ca":false},{"name":"Danna J. Leaman","is_ca":false},{"name":"Tony Durst","is_ca":true},{"name":"Bernard J. R. Philogène","is_ca":false},{"name":"J. T. Arnason","is_ca":true},{"name":"Pablo Sánchez-Vindas","is_ca":true},{"name":"L. Poveda","is_ca":false},{"name":"Pamela Tamez","is_ca":true},{"name":"John M. Pezzuto","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08628556810435459,"gpt":0.3572202083679681,"spread":0.2709346402636135,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001809535,0.0007662326,0.0006099403,0.001745195,0.000266198,0.0006087039,0.0005209255,0.0004086786,0.004266308],"category_scores_gemma":[0.0001582649,0.0001621087,0.0001900439,0.001550752,0.0003071685,0.0008264513,0.0003632437,0.0006096204,0.003900027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000461103,"about_ca_system_score_gemma":0.0004552562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007054103,"about_ca_topic_score_gemma":0.001599987,"domain_scores_codex":[0.9999331,0.000008211613,0.00000782639,0.00001328975,0.00002953035,0.000007998597],"domain_scores_gemma":[0.9999541,0.000009529964,0.000008225078,0.000003275169,0.00001656003,0.000008299793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006602446,0.00008896084,0.0001930685,0.006001485,0.00002839934,0.0002857156,0.00005234433,0.0002127999,0.01832108,0.002243795,0.007848674,0.9646577],"study_design_scores_gemma":[0.00002037966,0.0001064343,0.00134731,0.000478606,0.00002869802,0.001629916,0.00004798731,0.00005611227,0.003481661,0.001141806,0.9916528,0.000008367352],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001434287,0.9894638,0.0007699872,0.0003137637,0.0001978439,0.00001756134,0.00004203464,0.00004080837,0.007719904],"genre_scores_gemma":[0.006040111,0.9863961,0.001033949,0.0002722207,0.0001635746,0.00001637641,0.00009952098,0.000003526838,0.005974697],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004266308,"threshold_uncertainty_score":0.01427227,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2118971711","doi":"10.2174/156802610791113469","title":"Therapeutic Utility and Medicinal Chemistry of Cathepsin C Inhibitors","year":2010,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Proteases; Cathepsin C; Cathepsin G; Chemistry; Cathepsin; Biochemistry; Serine; Serine protease; Pharmacology; Serine Proteinase Inhibitors; Protease; Enzyme; Biology","authors":[{"name":"Daniel Guay","is_ca":true},{"name":"Christian Beaulieu","is_ca":false},{"name":"M. David Percival","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05911974874436363,"gpt":0.3784413533144509,"spread":0.3193216045700873,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003617685,0.0005797753,0.0003018677,0.000581885,0.0001963926,0.0006820087,0.0003328469,0.000526068,0.001822683],"category_scores_gemma":[0.0002791329,0.0002036649,0.000325478,0.0003732967,0.0003616018,0.0004253687,0.0003964987,0.001087602,0.0007267053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005426619,"about_ca_system_score_gemma":0.0002727853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004050267,"about_ca_topic_score_gemma":0.0005026627,"domain_scores_codex":[0.9998212,0.00004452069,0.000009052778,0.00003805479,0.00004897804,0.00003816302],"domain_scores_gemma":[0.9999183,0.00001548475,0.00002204642,0.000008065103,0.00001982643,0.00001624903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001138739,0.0007907007,0.0005177888,0.003135311,0.0001353372,0.0009395021,0.000170674,0.008990619,0.5662361,0.03246637,0.01073304,0.3747458],"study_design_scores_gemma":[0.0005334704,0.00700922,0.002536935,0.0005163897,0.0001561128,0.003517283,0.00008785022,0.005746041,0.5158852,0.007396983,0.4565062,0.0001082378],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2102938,0.6517928,0.03426382,0.004221703,0.001079563,0.0003544971,0.001486154,0.0004506419,0.09605715],"genre_scores_gemma":[0.710152,0.2661735,0.007471947,0.001505,0.0003799562,0.0001575912,0.0007735169,0.00003321521,0.01335328],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001822683,"threshold_uncertainty_score":0.006097496,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3003427449","doi":"10.2174/1568026620666200131125110","title":"Non-canonical Functions of Telomerase Reverse Transcriptase: Emerging Roles and Biological Relevance","year":2020,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"Cancer Research Society","keywords":"Telomerase; Telomere; Telomerase reverse transcriptase; Biology; Cell biology; DNA damage; Reverse transcriptase; Mitochondrion; Telomerase RNA component; Chromatin; Mitochondrial DNA; RNA; Context (archaeology); Genetics; Gene; DNA","authors":[{"name":"Connor A.H. Thompson","is_ca":true},{"name":"Judy M.Y. Wong","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06786236549586322,"gpt":0.3595202504898239,"spread":0.2916578849939607,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008078981,0.0005513426,0.0008114142,0.0007183843,0.0002520555,0.00176436,0.0007791701,0.001067405,0.0009228086],"category_scores_gemma":[0.0005745778,0.0002568624,0.0003070474,0.0008885136,0.001188825,0.002091173,0.0006345934,0.001729053,0.0005461815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006309992,"about_ca_system_score_gemma":0.000727628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003585021,"about_ca_topic_score_gemma":0.0005784922,"domain_scores_codex":[0.9997094,0.00003655492,0.00003061353,0.00009559701,0.00008022661,0.00004754874],"domain_scores_gemma":[0.999209,0.0002883783,0.0001849974,0.00004454654,0.0001732629,0.00009979555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005407634,0.0001440979,0.00826391,0.01197397,0.0001251092,0.002695005,0.000676209,0.001490287,0.1829752,0.05016194,0.009095053,0.7318586],"study_design_scores_gemma":[0.00006496345,0.0006883608,0.03182342,0.001811476,0.000329212,0.01181848,0.001671808,0.005115078,0.05252565,0.1047024,0.789273,0.0001762696],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009910936,0.9843131,0.002245425,0.001690507,0.0001814478,0.000004046844,0.00006769788,0.00002757731,0.001559248],"genre_scores_gemma":[0.07745986,0.9165379,0.002518192,0.0009090666,0.001122065,0.0000203638,0.0002483319,0.00001164564,0.001172548],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00176436,"threshold_uncertainty_score":0.004578292,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2074936715","doi":"10.2174/156802609787521580","title":"Drug Transport Across the Blood-Brain Barrier and the Impact of Breast Cancer Resistance Protein (ABCG2)","year":2009,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre for Drug Research and Development","funders":"","keywords":"Abcg2; Blood–brain barrier; P-glycoprotein; Efflux; Pharmacology; Drug; Transporter; ATP-binding cassette transporter; Drug resistance; Drug discovery; Paracellular transport; Biology; Multiple drug resistance; Medicine; Central nervous system; Neuroscience; Bioinformatics; Biochemistry; Permeability (electromagnetism)","authors":[{"name":"Joseph A. Nicolazzo","is_ca":false},{"name":"Kasiram Katneni","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01903273739826056,"gpt":0.3557991286743923,"spread":0.3367663912761318,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003892649,0.0004071688,0.0009955405,0.0009944314,0.0001683472,0.001016491,0.0004281501,0.0007812217,0.001975382],"category_scores_gemma":[0.0005945902,0.0001888873,0.0005130871,0.001369764,0.0003419014,0.0008952897,0.0002988592,0.0009498333,0.0009025653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006296479,"about_ca_system_score_gemma":0.0007696222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001380652,"about_ca_topic_score_gemma":0.002034662,"domain_scores_codex":[0.9997284,0.00005731492,0.00004797425,0.00004663671,0.00008330146,0.00003626934],"domain_scores_gemma":[0.9997837,0.00009433308,0.00004088674,0.000005171839,0.00006710872,0.00000878574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003308853,0.00007530506,0.001464782,0.04536947,0.0002779815,0.001853396,0.0002941483,0.001485987,0.03841338,0.01044332,0.03268122,0.8673101],"study_design_scores_gemma":[0.00002060298,0.0003220876,0.004846776,0.002052232,0.0002998624,0.00519272,0.0001366116,0.0003407525,0.009874319,0.001537894,0.9753387,0.00003747785],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00122383,0.9965307,0.0002862637,0.0005097627,0.0001399902,0.000005909506,0.00004649366,0.00001037956,0.001246749],"genre_scores_gemma":[0.007063099,0.990845,0.0003202625,0.0003535739,0.000166607,0.00001177849,0.00009235302,0.000002807015,0.001144481],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001975382,"threshold_uncertainty_score":0.006608307,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2333303354","doi":"10.2174/156802611797470376","title":"Thalamocortical Oscillations: Local Control of EEG Slow Waves","year":2011,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"National Institute of Neurological Disorders and Stroke; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Neocortex; Neuroscience; Electroencephalography; Reticular connective tissue; Thalamus; Oscillation (cell signaling); Reticular formation; Thalamic reticular nucleus; Mechanism (biology); Rhythm; Computer science; Nucleus; Physics; Biology; Anatomy","authors":[{"name":"Igor Timofeev","is_ca":true},{"name":"Sylvain Chauvette","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07932839974948033,"gpt":0.3424429070872604,"spread":0.2631145073377801,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000237774,0.0007208618,0.000787332,0.0010841,0.0001944826,0.0007260747,0.0006833223,0.0006664479,0.001710763],"category_scores_gemma":[0.000306617,0.0002139849,0.0002773635,0.0007386953,0.000644102,0.0008775209,0.0004734243,0.0008153073,0.001312669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003732457,"about_ca_system_score_gemma":0.0003865665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005235862,"about_ca_topic_score_gemma":0.0005046059,"domain_scores_codex":[0.9999133,0.00001327879,0.00001111003,0.00002376991,0.0000301851,0.000008352232],"domain_scores_gemma":[0.9999001,0.00004231768,0.00001706562,0.000005366704,0.00002594742,0.000009185468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007505242,0.00003352061,0.0003392019,0.007055538,0.0000617534,0.0003827726,0.0001390824,0.0006233748,0.01844448,0.01191071,0.006302299,0.9546321],"study_design_scores_gemma":[0.00004047548,0.0002925426,0.005058622,0.002267031,0.0001475891,0.007679926,0.0001845023,0.001216392,0.01333137,0.01714854,0.9525542,0.00007881165],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009368946,0.9907848,0.003427979,0.0002784199,0.0002526009,0.00001255268,0.00002584419,0.00005330689,0.004227654],"genre_scores_gemma":[0.01091985,0.9850832,0.00133051,0.0001539606,0.0005659626,0.00002330784,0.00005024417,0.000008763569,0.001864195],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001710763,"threshold_uncertainty_score":0.005723119,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2060292828","doi":"10.2174/1568026033452276","title":"Protein Tyrosine Phosphatase 1B: A Novel Target for Type 2 Diabetes and Obesity","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Autophosphorylation; Insulin receptor; Insulin; Endocrinology; Internal medicine; Protein tyrosine phosphatase; Type 2 diabetes; IRS2; Glucose homeostasis; Phosphorylation; Biology; Insulin receptor substrate; Insulin-like growth factor 1 receptor; Diabetes mellitus; Receptor; Medicine; Insulin resistance; Cell biology; Protein kinase A","authors":[{"name":"Chidambaram Ramachandran","is_ca":true},{"name":"Brian P. Kennedy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04656700247953985,"gpt":0.3420648421868669,"spread":0.2954978397073271,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003091714,0.0007596557,0.001001695,0.001072662,0.0002335212,0.000523912,0.0005616741,0.0009573427,0.003255597],"category_scores_gemma":[0.0001806477,0.0001856717,0.0002140055,0.001024662,0.0003444545,0.0007900462,0.0003921249,0.001210592,0.003656088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004206087,"about_ca_system_score_gemma":0.0005995604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004453097,"about_ca_topic_score_gemma":0.001064894,"domain_scores_codex":[0.9999152,0.00001142834,0.000007206855,0.00001795812,0.00003744493,0.00001078198],"domain_scores_gemma":[0.999931,0.00001460838,0.00001170226,0.000002853268,0.0000215132,0.00001838788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001232243,0.0001015314,0.0002441736,0.005076353,0.00005340766,0.0006902444,0.00004705906,0.0003214493,0.01029608,0.004691136,0.03438492,0.9439704],"study_design_scores_gemma":[0.00005722493,0.000122564,0.000993658,0.0005450738,0.00004932683,0.002932129,0.00003465608,0.0001294727,0.001535312,0.002459449,0.991128,0.0000132208],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003678539,0.9969081,0.0004455258,0.0005060233,0.0003555454,0.000005792515,0.000015271,0.00001506933,0.001380754],"genre_scores_gemma":[0.002089732,0.9943436,0.0005253819,0.0003688574,0.0003247752,0.00001034712,0.00004103537,0.000002482221,0.002293807],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003255597,"threshold_uncertainty_score":0.01089108,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2145727779","doi":"10.2174/1568026054750236","title":"Recent Advances in Non-Competitive mGlu5 Receptor Antagonists and their Potential Therapeutic Applications","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Nuvo Pharmaceuticals (Canada)","funders":"","keywords":"Metabotropic glutamate receptor; Neuroscience; Metabotropic receptor; Receptor; Glutamate receptor; Metabotropic glutamate receptor 5; Pharmacology; Medicine; Biology; Internal medicine","authors":[{"name":"Abdelmalik Slassi","is_ca":true},{"name":"Methvin Isaac","is_ca":false},{"name":"Louise Edwards","is_ca":false},{"name":"Alexander B. E. Minidis","is_ca":false},{"name":"David Wensbo","is_ca":false},{"name":"Jan P. Mattsson","is_ca":false},{"name":"Karolina Nilsson","is_ca":false},{"name":"Patrick Raboisson","is_ca":false},{"name":"Donald A. McLeod","is_ca":false},{"name":"Thomas M. Stormann","is_ca":false},{"name":"Lance G. Hammerland","is_ca":false},{"name":"Edwin C. Johnson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07072333692176577,"gpt":0.4247984037044641,"spread":0.3540750667826984,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007497018,0.000854769,0.0009256904,0.001037967,0.0002030023,0.0006515181,0.0006903398,0.0009307837,0.004516374],"category_scores_gemma":[0.0005297331,0.0003520383,0.0006767642,0.00101303,0.0003279171,0.001119827,0.0005642175,0.001589292,0.001835285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003891996,"about_ca_system_score_gemma":0.0005619212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005440167,"about_ca_topic_score_gemma":0.001162213,"domain_scores_codex":[0.9997953,0.0000426567,0.00002448987,0.00004225622,0.00006032512,0.00003515831],"domain_scores_gemma":[0.999743,0.00008467102,0.00005584348,0.00001133466,0.00007121119,0.00003377817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005565227,0.0005061608,0.00032608,0.01803703,0.0002068889,0.0007099004,0.0002548929,0.001649781,0.06414687,0.008239035,0.02446476,0.8809022],"study_design_scores_gemma":[0.0001891843,0.002343986,0.001693178,0.001255169,0.000436132,0.001886243,0.0001357299,0.001362048,0.02661445,0.003366378,0.9606305,0.00008703297],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003765736,0.9872766,0.002993605,0.0009254676,0.0003494562,0.000036325,0.00007439202,0.0000618731,0.004516537],"genre_scores_gemma":[0.01327058,0.9797712,0.002408981,0.001077733,0.0004925886,0.00005153634,0.0001749001,0.0000118195,0.002740661],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004516374,"threshold_uncertainty_score":0.01510876,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1981440072","doi":"10.2174/156802606778249810","title":"Serotonin Reuptake Inhibitors: The Corner Stone in Treatment of Depression for Half a Century – A Medicinal Chemistry Survey","year":2006,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Treatment of Major Depression","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Freie Universität Berlin; H. Lundbeck A/S; Merck KGaA; McGill University; Sanofi","keywords":"Reuptake inhibitor; Antidepressant; Reuptake; Medicine; Population; Depression (economics); Psychiatry; Broad spectrum; Pharmacology; Serotonin; Psychology; Chemistry; Internal medicine","authors":[{"name":"Ejner K. Moltzen","is_ca":false},{"name":"Benny Bang‐Andersen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08870736064322807,"gpt":0.3946901556649448,"spread":0.3059827950217168,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004553697,0.0006117072,0.001053402,0.001571689,0.0002409117,0.0006233645,0.0005947701,0.000749143,0.004630802],"category_scores_gemma":[0.0003131396,0.0002025481,0.0002704201,0.002167447,0.0002434642,0.001300277,0.000326358,0.001055015,0.003234856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003916966,"about_ca_system_score_gemma":0.000601446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006965857,"about_ca_topic_score_gemma":0.002072216,"domain_scores_codex":[0.9998485,0.0000243788,0.00001865672,0.00002433578,0.00007086228,0.00001319692],"domain_scores_gemma":[0.9998456,0.00005271514,0.00002720474,0.000004552077,0.00004695199,0.00002292434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009060484,0.0001379579,0.0001566243,0.006952913,0.00004685765,0.0001886074,0.00005010914,0.0002513517,0.002876928,0.001791829,0.03235436,0.9551017],"study_design_scores_gemma":[0.00005190614,0.0003093886,0.001821337,0.002454462,0.00008137536,0.001833028,0.00009302873,0.0001537545,0.0007210616,0.001751793,0.9907128,0.00001596986],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002995768,0.9967557,0.0001940018,0.0004909977,0.0002283982,0.000009531243,0.00001908174,0.00001363108,0.001989108],"genre_scores_gemma":[0.00084214,0.9969438,0.0003446662,0.0003164276,0.000270286,0.00000561148,0.00002912293,0.000001296343,0.001246727],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004630802,"threshold_uncertainty_score":0.0154916,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2342247785","doi":"10.2174/1568026615666150915112459","title":"Short Antimicrobial Peptides and Peptide Scaffolds as Promising Antibacterial Agents","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Antimicrobial; Antimicrobial peptides; Peptidomimetic; Antibiotics; Peptide; Bacteria; Combinatorial chemistry; Chemistry; Biology; Computational biology; Microbiology; Biochemistry","authors":[{"name":"Ronald Domalaon","is_ca":false},{"name":"George G. Zhanel","is_ca":false},{"name":"Frank Schweizer","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04021102440206558,"gpt":0.3329688069844394,"spread":0.2927577825823738,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002763581,0.0006276063,0.0006750295,0.001067518,0.0001881446,0.0006557066,0.0004208592,0.0007503369,0.002337161],"category_scores_gemma":[0.0002242194,0.0002137984,0.0002480472,0.0009202513,0.000338957,0.001043407,0.0004823187,0.0009975102,0.001548728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002347306,"about_ca_system_score_gemma":0.0003114737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001569657,"about_ca_topic_score_gemma":0.0003506865,"domain_scores_codex":[0.999885,0.0000188383,0.00001101317,0.00002142794,0.00004576121,0.000017961],"domain_scores_gemma":[0.9999359,0.00002000051,0.00001566082,0.000002405495,0.00001377495,0.00001229024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001357838,0.000173881,0.0002701734,0.01638573,0.00005863697,0.0005801375,0.0001385325,0.0009589178,0.06157836,0.0125637,0.01299263,0.8941635],"study_design_scores_gemma":[0.00002422668,0.0003607336,0.0008413882,0.001409858,0.00006241439,0.002014837,0.00007550918,0.0002854152,0.01181153,0.00283507,0.9802491,0.00003005857],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001367536,0.9958574,0.0004560082,0.0001449013,0.0001642691,0.00000785411,0.00002409088,0.00001239108,0.001965533],"genre_scores_gemma":[0.006487794,0.9909688,0.0006949837,0.0001508179,0.0001974961,0.00001304891,0.00003833422,0.000002560851,0.001446296],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002337161,"threshold_uncertainty_score":0.00781858,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2901592444","doi":"10.2174/1568026618666181115100610","title":"Recognizing the Leaky Gut as a Trans-diagnostic Target for Neuroimmune Disorders Using Clinical Chemistry and Molecular Immunology Assays","year":2018,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Intestinal permeability; Dysbiosis; Immunology; Gut flora; Irritable bowel syndrome; Medicine; Microbiology; Biology; Internal medicine","authors":[{"name":"Denitsa Simeonova","is_ca":false},{"name":"Mariya Ivanovska","is_ca":false},{"name":"Marianna Murdjeva","is_ca":false},{"name":"André F. Carvalho","is_ca":true},{"name":"Michaël Maes","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06746993243660257,"gpt":0.411091357928049,"spread":0.3436214254914464,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001993334,0.0005628885,0.001810243,0.007523345,0.000193009,0.001528354,0.0004871587,0.0009187926,0.002930065],"category_scores_gemma":[0.003716606,0.0001793357,0.001028477,0.005707566,0.0005162413,0.001386887,0.0005606033,0.0005232176,0.000723661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005326647,"about_ca_system_score_gemma":0.001502185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009022209,"about_ca_topic_score_gemma":0.00166018,"domain_scores_codex":[0.9985783,0.0004073779,0.0004056684,0.0001670091,0.0003726896,0.00006892992],"domain_scores_gemma":[0.9969806,0.00164144,0.0007835355,0.00005581641,0.0004751166,0.00006333689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0008856229,0.0001965255,0.05435251,0.1743846,0.001585019,0.003694189,0.00044395,0.0003115584,0.01384392,0.003964528,0.02298729,0.7233503],"study_design_scores_gemma":[0.0003516459,0.00178881,0.1849093,0.08388276,0.006786403,0.02723072,0.002202508,0.0008156582,0.019814,0.008864789,0.6630234,0.0003300495],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007316454,0.98414,0.00152698,0.001612897,0.0003562043,0.0001193439,0.0008624853,0.00004647595,0.004019133],"genre_scores_gemma":[0.06295309,0.9228294,0.007758258,0.002731676,0.0008378526,0.0002232771,0.001191863,0.00001586667,0.00145868],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007523345,"threshold_uncertainty_score":0.01054186,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W7946861","doi":"10.2174/1568026054367610","title":"Voltage Gated Calcium Channels as Targets for Analgesics","year":2005,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Neuroscience; Voltage-dependent calcium channel; Sodium channel; Neurotransmission; Noxious stimulus; Ion channel; Nociception; Medicine; T-type calcium channel; Potassium channel; Calcium; Chemistry; Biology; Receptor; Sodium; Internal medicine","authors":[{"name":"Emmanuel Bourinet","is_ca":false},{"name":"Gerald W. Zamponi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1024904714632812,"gpt":0.4244511962638716,"spread":0.3219607248005903,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005858506,0.0008307833,0.001252158,0.001688,0.0003364322,0.0007851761,0.0008901284,0.001219863,0.004163693],"category_scores_gemma":[0.0004608257,0.0002653762,0.0003899441,0.001458051,0.0005448483,0.001707616,0.0004633975,0.001691776,0.002863268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006944597,"about_ca_system_score_gemma":0.0007295312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005475056,"about_ca_topic_score_gemma":0.001002518,"domain_scores_codex":[0.9998085,0.00003442011,0.00002015907,0.00003147963,0.00007923615,0.0000261998],"domain_scores_gemma":[0.9998431,0.00005892534,0.00002163787,0.000005611871,0.00005150384,0.00001910819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002100053,0.0001780155,0.0001773347,0.01098846,0.00005773093,0.0006608231,0.0000945143,0.0006284986,0.01509064,0.01046387,0.02604169,0.9354084],"study_design_scores_gemma":[0.00006866144,0.0002355779,0.0008142202,0.00173191,0.0000768375,0.001672461,0.00007972976,0.0002366321,0.003511251,0.006475351,0.985076,0.00002131506],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000283697,0.9969965,0.0002727752,0.0003629842,0.0002703307,0.00000637311,0.000008538418,0.00001075627,0.001787897],"genre_scores_gemma":[0.001910996,0.9954371,0.0004270789,0.0003296763,0.0003035359,0.00000874741,0.00001862837,0.000001790464,0.001562501],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004163693,"threshold_uncertainty_score":0.01392889,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1966039777","doi":"10.2174/156802607780487795","title":"Nucleobase Modifications in Peptide Nucleic Acids","year":2007,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleic acid; Nucleobase; Peptide nucleic acid; Oligonucleotide; DNA; Nucleic acid analogue; Chemistry; RNA; Combinatorial chemistry; Polyamide; Peptide; Glycine; Nucleic acid methods; Biochemistry; Amino acid; Nucleic acid thermodynamics; Organic chemistry; Gene","authors":[{"name":"Filip Wojciechowski","is_ca":true},{"name":"Robert H. E. Hudson","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05642702863086606,"gpt":0.3709538644284818,"spread":0.3145268357976158,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002108256,0.0007100402,0.0005976622,0.0007333251,0.0001779468,0.000343266,0.0004528372,0.0006251882,0.001326485],"category_scores_gemma":[0.0001716458,0.0002705875,0.0001707124,0.0008884155,0.0002991468,0.0005037769,0.0003589111,0.0006874091,0.002242656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003385225,"about_ca_system_score_gemma":0.0002395749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003318489,"about_ca_topic_score_gemma":0.0005006018,"domain_scores_codex":[0.9998772,0.00001809748,0.000009850247,0.00002998381,0.00005192649,0.00001282951],"domain_scores_gemma":[0.999958,0.00001472308,0.000009273316,0.000002887572,0.000009735764,0.00000529233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008554042,0.0001163173,0.0001511634,0.00933491,0.00005005762,0.000797345,0.0001433172,0.0009765288,0.2189527,0.008638482,0.007280299,0.7534734],"study_design_scores_gemma":[0.00002163114,0.00026002,0.0006367682,0.0006233586,0.00004037014,0.003472531,0.0000348384,0.0002263257,0.09190238,0.001761758,0.9009942,0.00002576389],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004266998,0.9847088,0.002497906,0.0001518404,0.0003436984,0.0000263054,0.00003291297,0.00005154967,0.007919985],"genre_scores_gemma":[0.01952802,0.9689806,0.003502871,0.0002548307,0.0002022128,0.00004248927,0.00008344676,0.000009509633,0.00739612],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001326485,"threshold_uncertainty_score":0.004437506,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3198782994","doi":"10.2174/1568026621666210909160210","title":"Investigation of the Relationship among Cortisol, Pro-inflammatoryCytokines, and the Degradation of Tryptophan into Kynurenine inPatients with Major Depression and Suicidal Behavior","year":2021,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University; McGill University Health Centre","funders":"","keywords":"Major depressive disorder; Proinflammatory cytokine; Kynurenine; Internal medicine; Depression (economics); Endocrinology; Medicine; Inflammation; Tryptophan; Psychology; Chemistry; Amygdala; Biochemistry","authors":[{"name":"R. Mensi","is_ca":false},{"name":"Wahiba Douki","is_ca":false},{"name":"Fadoua Neffati","is_ca":false},{"name":"Mohamed Fadhel Najjar","is_ca":false},{"name":"Gabriella Gobbi","is_ca":true},{"name":"Mirko Manchia","is_ca":true},{"name":"Flavia Valtorta","is_ca":false},{"name":"Gaha Lotfi","is_ca":false},{"name":"Stefano Comai","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02827212171219867,"gpt":0.268529918443539,"spread":0.2402577967313403,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003178713,0.0002038677,0.0003263561,0.0003790946,0.0002372902,0.0003711616,0.0001235183,0.0002248923,0.0009657899],"category_scores_gemma":[0.001136344,0.0001548547,0.0001731085,0.0002864051,0.0001590902,0.0001459982,0.0002315391,0.0003733789,0.0001678346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002479976,"about_ca_system_score_gemma":0.0001987007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046059,"about_ca_topic_score_gemma":0.001770449,"domain_scores_codex":[0.9998032,0.00005360003,0.00002776861,0.00003354127,0.00004360095,0.00003829836],"domain_scores_gemma":[0.9993573,0.00009880091,0.0002826826,0.00002600597,0.00009515528,0.0001399729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001717218,0.00005050014,0.997715,0.00001186951,0.00004176686,0.00007173959,0.0001031792,0.00001330499,0.0006059881,0.000006005771,0.00002467794,0.001184243],"study_design_scores_gemma":[0.000005003017,0.000176041,0.9991437,0.000003365947,0.00001993069,0.0002361818,0.0001802667,0.00008190366,0.0001025033,0.000008841219,0.00004083072,0.000001404514],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997255,0.000124053,0.00002289602,0.00001296049,0.000001787023,0.000003262127,0.0000351378,7.13091e-7,0.00007360715],"genre_scores_gemma":[0.9997991,0.00005715816,0.00003395136,0.000006294264,0.000002616955,0.00000317172,0.00005726422,2.235489e-7,0.0000402296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001046059,"threshold_uncertainty_score":0.003230929,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2336090556","doi":"10.2174/1568026616666160414124816","title":"Overview of the Genetic Basis and Epigenetic Mechanisms that Contribute to FASD Pathobiology","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Epigenetics; DNA methylation; Phenotype; Epigenome; Biology; Genetics; Histone; Bioinformatics; Gene; Gene expression","authors":[{"name":"Vichithra R. B. Liyanage","is_ca":false},{"name":"Kyle Curtis","is_ca":false},{"name":"Robby M. Zachariah","is_ca":false},{"name":"Albert E. Chudley","is_ca":false},{"name":"Mojgan Rastegar","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05806341845818775,"gpt":0.350892113721131,"spread":0.2928286952629433,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002868133,0.0006379818,0.0005437927,0.001581049,0.0002877638,0.0007379755,0.0004420965,0.000722753,0.003810825],"category_scores_gemma":[0.0002282186,0.0002645706,0.0005340625,0.000860546,0.0003037546,0.0008695422,0.0004157241,0.001301318,0.0007880154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007166519,"about_ca_system_score_gemma":0.001000507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001730703,"about_ca_topic_score_gemma":0.002432818,"domain_scores_codex":[0.9999021,0.00001616702,0.00001831514,0.00002683951,0.00002204371,0.00001446428],"domain_scores_gemma":[0.9998455,0.00005585533,0.00003340418,0.000005574025,0.00003701881,0.00002264991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003288504,0.0001471729,0.003483586,0.01550907,0.0002950648,0.001266049,0.0002402264,0.0008563051,0.02938566,0.01332647,0.04146414,0.8936974],"study_design_scores_gemma":[0.0000265797,0.0003277724,0.01007017,0.003589088,0.0005204229,0.005479476,0.000194607,0.0004997069,0.004524827,0.009591812,0.9651236,0.00005209072],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002154111,0.9876902,0.001900731,0.002232234,0.0003553413,0.00002101989,0.0002227144,0.00006844367,0.005355162],"genre_scores_gemma":[0.005338679,0.9889683,0.001801379,0.0007556917,0.0004639771,0.00002424373,0.0003859868,0.000005860451,0.002255856],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003810825,"threshold_uncertainty_score":0.01274848,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2054916058","doi":"10.2174/1568026023394470","title":"Multivariate Pharmaceutical Profiling for Drug Discovery","year":2002,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":45,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Profiling (computer programming); Drug discovery; Drug; Computer science; Computational biology; Data science; Medicine; Pharmacology; Bioinformatics; Biology","authors":[{"name":"Edward H. Kerns","is_ca":true},{"name":"Li Di","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1624377812755547,"gpt":0.4649525684676644,"spread":0.3025147871921097,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001780352,0.001272074,0.001826523,0.002199331,0.0005054187,0.002101487,0.001229419,0.001512,0.00859227],"category_scores_gemma":[0.002545185,0.0003681924,0.0006036999,0.004833066,0.001535457,0.002412502,0.001270008,0.002349099,0.006310443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001347937,"about_ca_system_score_gemma":0.001524166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001163692,"about_ca_topic_score_gemma":0.001167076,"domain_scores_codex":[0.9986001,0.0004980547,0.00007063004,0.0001584143,0.0006243384,0.00004846741],"domain_scores_gemma":[0.9991136,0.0004730017,0.0000880921,0.0001262044,0.0001587564,0.00004028399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006532187,0.00007498465,0.0003506243,0.003461275,0.00009677682,0.0001396251,0.00006959461,0.005538104,0.003215306,0.1247013,0.03876753,0.8235195],"study_design_scores_gemma":[0.00002497246,0.0001118619,0.0007076009,0.0008856943,0.00005002321,0.0007777039,0.00005452157,0.006941755,0.002898764,0.09472796,0.8927628,0.00005641171],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001358316,0.742678,0.200164,0.0056969,0.001810921,0.0001728505,0.0003333385,0.001010035,0.04677569],"genre_scores_gemma":[0.03018355,0.7997847,0.1430779,0.002625622,0.002376211,0.0003422179,0.0005108918,0.0001647072,0.02093425],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00859227,"threshold_uncertainty_score":0.02874404,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2137551797","doi":"10.2174/156802612801319070","title":"DNA Repair Inhibitors: The Next Major Step to Improve Cancer Therapy","year":2012,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Allard Foundation","keywords":"ERCC1; Nucleotide excision repair; DNA repair; Base excision repair; DNA polymerase; Context (archaeology); DNA damage; Xeroderma pigmentosum; Cisplatin; Cancer; Cancer research; Bleomycin; DNA polymerase beta; Biology; DNA; Medicine; Computational biology; Bioinformatics; Genetics; Chemotherapy","authors":[{"name":"Khaled Barakat","is_ca":true},{"name":"Melissa Gajewski","is_ca":false},{"name":"Jack A. Tuszyński","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05511950255063542,"gpt":0.3553384109138121,"spread":0.3002189083631767,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007794326,0.000822147,0.001333806,0.0009522539,0.0003408765,0.002108535,0.0008268598,0.001413784,0.009777563],"category_scores_gemma":[0.0006587913,0.0003213872,0.0005254709,0.0006482194,0.0006188423,0.00260824,0.0008238652,0.003992984,0.006472575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009152919,"about_ca_system_score_gemma":0.0009128137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003521281,"about_ca_topic_score_gemma":0.0008922159,"domain_scores_codex":[0.9997073,0.00006277391,0.00002107424,0.00005144932,0.0001070276,0.00005030646],"domain_scores_gemma":[0.9997227,0.00007140389,0.00004499167,0.00001765918,0.00008646012,0.0000568162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005852588,0.0005807552,0.0005602721,0.009812047,0.0002123875,0.0005005644,0.000182677,0.00149064,0.06097722,0.04264415,0.1322553,0.7501987],"study_design_scores_gemma":[0.0001097055,0.0006334802,0.0004783714,0.0007489802,0.00008626125,0.0007068852,0.00007193176,0.0005120095,0.008006711,0.01080954,0.9777973,0.00003885308],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005426078,0.9422932,0.009338953,0.02031182,0.003288818,0.0001378182,0.0006654184,0.0004691311,0.01806878],"genre_scores_gemma":[0.0255044,0.9368986,0.008577293,0.009954068,0.001844087,0.0001259562,0.0008134347,0.00008498475,0.01619703],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009777563,"threshold_uncertainty_score":0.03270924,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2099524467","doi":"10.2174/156802606776287054","title":"Targeting Serine Proteases in Asthma","year":2006,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Proteases; Asthma; Serine; Medicine; Chemistry; Biochemistry; Immunology; Enzyme","authors":[{"name":"Caroline Guay","is_ca":true},{"name":"Michel Laviolette","is_ca":false},{"name":"Guy M. Tremblay","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02535599580841364,"gpt":0.3353388599392942,"spread":0.3099828641308806,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000251262,0.0007468975,0.0008046458,0.001167735,0.0002299459,0.0005035182,0.0004651796,0.0008109076,0.00282591],"category_scores_gemma":[0.0001356171,0.0002321716,0.0002423918,0.001040983,0.0002909667,0.0006157556,0.0003979304,0.001029622,0.00368007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000498929,"about_ca_system_score_gemma":0.0003672351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005327295,"about_ca_topic_score_gemma":0.0008897044,"domain_scores_codex":[0.9999069,0.00001234151,0.000009925678,0.00001717606,0.00004097809,0.00001264372],"domain_scores_gemma":[0.9999597,0.000009583689,0.000009420964,0.000002441678,0.00001107305,0.00000775857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000159285,0.0001727087,0.0001469951,0.006904105,0.00004919932,0.0005281894,0.00006583603,0.0007005656,0.06135883,0.004421002,0.0175268,0.9079665],"study_design_scores_gemma":[0.00006658683,0.0003381823,0.001046794,0.0007797629,0.00006235111,0.003228776,0.00003578475,0.0002583564,0.01533113,0.00211459,0.9767165,0.00002124937],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001056428,0.9946833,0.0007348757,0.0002459278,0.0002080521,0.00001415178,0.00002622427,0.00003689771,0.002994202],"genre_scores_gemma":[0.004824588,0.989657,0.001149455,0.0002398331,0.0001633161,0.00001732353,0.00005901908,0.000004740699,0.003884692],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00282591,"threshold_uncertainty_score":0.009453654,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2162928407","doi":"10.2174/1568026043387836","title":"Inhibitors of 3C Cysteine Proteinases from Picornaviridae","year":2004,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Natural Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Picornavirus; Picornaviridae; Enzyme; Biochemistry; Cysteine; Rhinovirus; Biology; Chemistry; Virology; Virus; RNA; Gene","authors":[{"name":"Manjinder S. Lall","is_ca":false},{"name":"Rajendra Jain","is_ca":false},{"name":"John C. Vederas","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08030012419379993,"gpt":0.4155885129530493,"spread":0.3352883887592493,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002065099,0.0008930596,0.0008775711,0.001471883,0.000260599,0.0004629388,0.0005974569,0.0005696287,0.001848646],"category_scores_gemma":[0.0001725492,0.0002405509,0.0002487288,0.001136555,0.0002556084,0.0006089769,0.0002864278,0.0007357253,0.001820933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000398369,"about_ca_system_score_gemma":0.0003067387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005536117,"about_ca_topic_score_gemma":0.0008910673,"domain_scores_codex":[0.9998993,0.000009628025,0.000009295065,0.00001886831,0.00005069639,0.00001221763],"domain_scores_gemma":[0.9999468,0.00001267254,0.00001168715,0.000002770782,0.00001675168,0.000009252788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001469108,0.0001764784,0.0002258696,0.00843865,0.0000540176,0.0005347335,0.00008897303,0.0007976248,0.04178564,0.002874713,0.008922366,0.935954],"study_design_scores_gemma":[0.00006980909,0.0004520043,0.002260373,0.0007419412,0.00007342734,0.003160415,0.00005118864,0.0003967142,0.02685068,0.001451956,0.9644576,0.0000339814],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003365943,0.9890021,0.001225153,0.0001449833,0.000223429,0.00003191945,0.00003770544,0.00005439778,0.0059143],"genre_scores_gemma":[0.01289369,0.9792821,0.001405864,0.0001917498,0.0001838365,0.000055303,0.0001298423,0.000005266328,0.005852302],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001848646,"threshold_uncertainty_score":0.00618434,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2322941916","doi":"10.2174/156802612805219969","title":"Recent Developments in the Regulation of Monoamine Oxidase Form and Function: Is the Current Model Restricting Our Understanding of the Breadth of Contribution of Monoamine Oxidase to Brain [dys]Function?","year":2012,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Monoamine neurotransmitter; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase A; Dopamine; Serotonin; Chemistry; Neuroscience; Biochemistry; Biology; Enzyme; Receptor","authors":[{"name":"Darrell D. Mousseau","is_ca":true},{"name":"Glen B. Baker","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1351280451325707,"gpt":0.3552206289526678,"spread":0.2200925838200971,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004613571,0.0006764515,0.001330895,0.0008058755,0.0005495981,0.002182554,0.001795376,0.0024263,0.001703077],"category_scores_gemma":[0.002695048,0.0003697287,0.0004782198,0.001291288,0.003634189,0.006321237,0.001150847,0.004834955,0.0008347195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001575754,"about_ca_system_score_gemma":0.00168818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001350562,"about_ca_topic_score_gemma":0.001625502,"domain_scores_codex":[0.9991283,0.0002442648,0.0001115755,0.0002277928,0.0001986187,0.00008944773],"domain_scores_gemma":[0.9958947,0.002000421,0.0005322291,0.0003574635,0.0009271862,0.0002880386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009000801,0.0002614972,0.003817407,0.009924142,0.0001756716,0.001187931,0.001005911,0.001662736,0.0416165,0.1228459,0.02874328,0.787859],"study_design_scores_gemma":[0.00003454871,0.0007781854,0.007168047,0.002152607,0.0002542137,0.003747257,0.001242476,0.001954741,0.01543278,0.1005828,0.8664625,0.0001898144],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003287875,0.9672308,0.00619231,0.01919712,0.001490063,0.000007251241,0.00004527831,0.00005030854,0.002498974],"genre_scores_gemma":[0.02809413,0.9527635,0.005505934,0.006367999,0.005656331,0.00002737173,0.00009786063,0.00002089652,0.001466005],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004613571,"threshold_uncertainty_score":0.02439922,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2586156640","doi":"10.2174/1568026617666170104143618","title":"Novel Colchicine Derivatives and their Anti-cancer Activity","year":2017,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Pharmacophore; Colchicine; Tubulin; Cancer; Cancer cell lines; Cancer cell; Computational biology; Chemistry; Cancer research; Biology; Biochemistry; Pharmacology; Microtubule; Cell biology; Genetics","authors":[{"name":"Lorelei Johnson","is_ca":true},{"name":"Ing Swie Goping","is_ca":true},{"name":"Aja M. Rieger","is_ca":true},{"name":"Jonathan Y. Mane","is_ca":true},{"name":"Torin Huzil","is_ca":true},{"name":"Asok Banerjee","is_ca":false},{"name":"Richard F. Ludueña","is_ca":false},{"name":"Bashar Hassani","is_ca":true},{"name":"Philip Winter","is_ca":true},{"name":"Jack A. Tuszyński","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2306223384753882,"gpt":0.4199642387482792,"spread":0.189341900272891,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001273384,0.0006215018,0.000492939,0.00134789,0.0002027784,0.0004756779,0.0003623067,0.0005010883,0.004306043],"category_scores_gemma":[0.0001800393,0.0001872596,0.0002448171,0.001026553,0.0002123544,0.0004942839,0.0003224583,0.0009315099,0.001718844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003835007,"about_ca_system_score_gemma":0.0003137214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007659339,"about_ca_topic_score_gemma":0.001876175,"domain_scores_codex":[0.9999319,0.000008122106,0.000006779947,0.00001459903,0.00002741603,0.00001115761],"domain_scores_gemma":[0.9999508,0.00001548171,0.000009873685,0.000002110499,0.00001419729,0.000007584936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001406298,0.0001499636,0.0001860333,0.01952063,0.00007573868,0.0004893778,0.00007773023,0.001189035,0.05267993,0.006614367,0.01736021,0.9015164],"study_design_scores_gemma":[0.00002082771,0.0003354402,0.0008843981,0.0009254509,0.0000887826,0.001599859,0.00004185111,0.000248212,0.0186935,0.0009983834,0.9761339,0.00002945273],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001924974,0.9914553,0.0006325488,0.0001935995,0.0002250454,0.00001879058,0.0001017892,0.00003014318,0.005417814],"genre_scores_gemma":[0.01079221,0.9843536,0.0007321116,0.0002181408,0.0001491644,0.0000204124,0.0001481385,0.000005567367,0.003580787],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004306043,"threshold_uncertainty_score":0.01440519,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1995536355","doi":"10.2174/1568026043387610","title":"The Use of DNA Microarrays to Investigate the Pharmacogenomics of Drug Response in Living Systems","year":2004,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Northeast Cancer Centre","funders":"","keywords":"Pharmacogenomics; Drug response; DNA microarray; Drug; Computational biology; Pharmacology; Medicine; Biology; Genetics; Gene; Gene expression","authors":[{"name":"David J. Villeneuve","is_ca":true},{"name":"Amadeo M. Parissenti","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08537657184318984,"gpt":0.3582409770211075,"spread":0.2728644051779177,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001622728,0.0009108637,0.001888375,0.003025504,0.0003732846,0.001300084,0.001188752,0.001290314,0.001264705],"category_scores_gemma":[0.0009262105,0.0004552391,0.0005644522,0.003496557,0.001086541,0.001609483,0.0005146646,0.001558431,0.002555859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001006647,"about_ca_system_score_gemma":0.000575878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000936819,"about_ca_topic_score_gemma":0.001319284,"domain_scores_codex":[0.9991164,0.0002121996,0.00004733085,0.0001633695,0.0004163703,0.00004438623],"domain_scores_gemma":[0.9994633,0.0002734897,0.00005371882,0.00003881899,0.0001472978,0.00002344298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001250147,0.0001184579,0.0006481274,0.006297921,0.0001181689,0.0002974859,0.0001402784,0.001445342,0.1936095,0.01400918,0.01008784,0.7731026],"study_design_scores_gemma":[0.00004396167,0.0003549068,0.003481082,0.0009830934,0.0001448547,0.002511618,0.0001830074,0.00207224,0.1442302,0.01409988,0.8317738,0.0001213501],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003773119,0.9176087,0.06362461,0.001847511,0.0008378039,0.0001479887,0.0002679688,0.0003591178,0.01153318],"genre_scores_gemma":[0.01383615,0.9147118,0.06300109,0.00138495,0.0005318049,0.0002475855,0.000359392,0.000030606,0.005896579],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003025504,"threshold_uncertainty_score":0.008581877,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2079534288","doi":"10.2174/1568026033452311","title":"Inhibitors of Protein Tyrosine Phosphatase 1B (PTP1B)","year":2003,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Protein tyrosine phosphatase; Phosphatase; Insulin; Tyrosine; Diabetes mellitus; Insulin receptor; Computational biology; Chemistry; Medicine; Biochemistry; Enzyme; Biology; Internal medicine; Endocrinology; Insulin resistance","authors":[{"name":"Scott D. Taylor","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0314126420675822,"gpt":0.3344851856915182,"spread":0.303072543623936,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003990383,0.00106107,0.001089594,0.001612715,0.0002343947,0.0005265318,0.0006702284,0.0006961726,0.003092442],"category_scores_gemma":[0.0003507334,0.0002117608,0.000299479,0.001579761,0.0002921704,0.0008436229,0.0005514291,0.001133016,0.003762517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003850056,"about_ca_system_score_gemma":0.0003443126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004548392,"about_ca_topic_score_gemma":0.0009054603,"domain_scores_codex":[0.9998459,0.00001540515,0.00001454367,0.00003615363,0.00007008396,0.0000179257],"domain_scores_gemma":[0.9998648,0.00004249015,0.00003088563,0.000006175065,0.00003267005,0.00002293411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008358059,0.0001299026,0.0001654711,0.005446412,0.00005153004,0.000285106,0.00003063591,0.000286842,0.01154327,0.00140997,0.01438052,0.9661867],"study_design_scores_gemma":[0.00005069904,0.0002764922,0.001193654,0.0007648711,0.0001057667,0.003187003,0.00002977835,0.0001055907,0.00646787,0.001006969,0.986791,0.00002022323],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004507916,0.9965795,0.0005816423,0.0001477587,0.0001893991,0.00001102299,0.00002134488,0.00002492064,0.001993575],"genre_scores_gemma":[0.002048007,0.9948463,0.0006011982,0.0001756948,0.0001376557,0.00001244239,0.00005096945,0.000002318636,0.002125418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003092442,"threshold_uncertainty_score":0.01034522,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2128824604","doi":"10.2174/15680266113139990004","title":"A Challenge for Medicinal Chemistry by the 17&amp;#946;-hydroxysteroid Dehydrogenase Superfamily: An Integrated Biological Function and Inhibition Study","year":2013,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Hydroxysteroid dehydrogenase; Enzyme; Steroid; Dehydrogenase; Dihydrotestosterone; Chemistry; Estrogen; Androgen; Prostate cancer; Receptor; Hormone; Cancer; Biochemistry; Cancer research; Biology; Endocrinology; Genetics","authors":[{"name":"Sheng‐Xiang Lin","is_ca":true},{"name":"Donald Poirier","is_ca":true},{"name":"Jerzy Adamski","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05925358796845578,"gpt":0.3427177011190026,"spread":0.2834641131505469,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001901087,0.0007596572,0.001020517,0.0005416052,0.0005688342,0.001706279,0.0009013076,0.00169672,0.006480522],"category_scores_gemma":[0.001086326,0.0003722169,0.000743164,0.0007328664,0.00141128,0.004193615,0.001659682,0.004070273,0.00340805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00116068,"about_ca_system_score_gemma":0.001375746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007249909,"about_ca_topic_score_gemma":0.0008809076,"domain_scores_codex":[0.9993733,0.000169421,0.00002854826,0.0001258025,0.000205693,0.00009721894],"domain_scores_gemma":[0.9995667,0.00009247725,0.00004322037,0.00005303011,0.0001479652,0.00009648446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003645204,0.0007139434,0.0006579834,0.002636027,0.0001236258,0.0005504784,0.0005262725,0.003747977,0.06336632,0.1482233,0.08425594,0.6948336],"study_design_scores_gemma":[0.0001887331,0.001899119,0.0007922223,0.000650977,0.00006504986,0.001038527,0.0004005105,0.00617225,0.02153262,0.05473968,0.9124327,0.00008772385],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03256608,0.7658401,0.05859662,0.07435536,0.006217895,0.0002231715,0.0004270518,0.0005487776,0.0612249],"genre_scores_gemma":[0.2230774,0.6567362,0.03591992,0.02401853,0.005901661,0.0003427077,0.0007805864,0.0002074551,0.05301562],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006480522,"threshold_uncertainty_score":0.02167946,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2514026372","doi":"10.2174/1568026616666160824104052","title":"Heterocyclic Amaryllidaceae Alkaloids: Biosynthesis and Pharmacological Applications","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"Amaryllidaceae Alkaloids; Amaryllidaceae; Biosynthesis; Chemistry; Traditional medicine; Biology; Botany; Biochemistry; Medicine; Gene","authors":[{"name":"Tarun Hotchandani","is_ca":false},{"name":"Isabel Desgagné‐Penix","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0473759608073837,"gpt":0.3552078843769329,"spread":0.3078319235695492,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001482011,0.0005099533,0.0005609526,0.001335994,0.0002558261,0.0005830184,0.0003992078,0.0005161921,0.005206989],"category_scores_gemma":[0.0001794024,0.0002102011,0.0002921333,0.001075864,0.0001845564,0.000703843,0.0004128896,0.0007850451,0.00323976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003275821,"about_ca_system_score_gemma":0.0004647375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005419886,"about_ca_topic_score_gemma":0.001342978,"domain_scores_codex":[0.9999243,0.000007328963,0.000008798833,0.00001740676,0.00003162794,0.00001057353],"domain_scores_gemma":[0.9999311,0.00001667219,0.00001525773,0.000003104732,0.00002302677,0.00001087078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001352,0.0001379957,0.0003067662,0.01994269,0.00007385857,0.000497168,0.000109855,0.00062069,0.05785506,0.004911674,0.0131547,0.9022543],"study_design_scores_gemma":[0.00001566209,0.0001903428,0.001343131,0.001120382,0.00007489495,0.001676247,0.00004908635,0.0002143084,0.0101154,0.001461145,0.9837183,0.00002108297],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001788129,0.9903916,0.0005701113,0.0002033118,0.000142272,0.00001607499,0.0001199579,0.00002913059,0.006739371],"genre_scores_gemma":[0.01041852,0.9831717,0.0009985199,0.0001810263,0.0001498707,0.00001470221,0.0002064001,0.000007236131,0.00485205],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005206989,"threshold_uncertainty_score":0.01741916,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3205803446","doi":"10.2174/1568026621666211012111901","title":"Therapeutic Potential of Indole Derivatives as Anti-HIV Agents: AMini-review","year":2021,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Henan Provincial Science and Technology Research Project; Key Scientific Research Project of Colleges and Universities in Henan Province; Henan Province Science and Technology Innovation Talent Program","keywords":"Indole test; Human immunodeficiency virus (HIV); Pharmacology; Medicine; Chemistry; Virology; Stereochemistry","authors":[{"name":"Qingtai Chen","is_ca":false},{"name":"Chongchong Wu","is_ca":true},{"name":"Jinjin Zhu","is_ca":false},{"name":"Enzhong Li","is_ca":false},{"name":"Zhi Xu","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08487877388222492,"gpt":0.4100375049386015,"spread":0.3251587310563765,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002381649,0.0007235046,0.0007059022,0.001615571,0.0002123066,0.0005809493,0.0005271512,0.0005695001,0.003001151],"category_scores_gemma":[0.0002568379,0.0002276844,0.00038022,0.001458967,0.0001972412,0.0007879013,0.000355501,0.0008411502,0.001357637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002948517,"about_ca_system_score_gemma":0.0004203318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004007213,"about_ca_topic_score_gemma":0.0007975089,"domain_scores_codex":[0.999918,0.00001168586,0.000009241402,0.00001639,0.00003140766,0.00001328944],"domain_scores_gemma":[0.9999108,0.00003797651,0.00001641776,0.00000308308,0.00002124065,0.00001043234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001138565,0.0001401622,0.0001854541,0.02275291,0.00008316699,0.0003841706,0.00008797279,0.0006497096,0.01140409,0.004455348,0.02012138,0.9396218],"study_design_scores_gemma":[0.00001958156,0.0002600331,0.0007732322,0.001608503,0.0001160494,0.001344376,0.00005812153,0.0001923751,0.003493674,0.001036563,0.9910767,0.0000207081],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006378033,0.9968773,0.000206604,0.0001096044,0.0002295146,0.000008823486,0.00002347734,0.00001063856,0.001896226],"genre_scores_gemma":[0.002429235,0.9959261,0.0002424333,0.0001220598,0.0001512509,0.000009741359,0.00003805496,0.000001676945,0.001079514],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003001151,"threshold_uncertainty_score":0.01003987,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2007374093","doi":"10.2174/1568026023393903","title":"Recent Advances in 5-HT1B / 1D Receptor Antagonists and Agonists and their Potential Therapeutic Applications","year":2002,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Nuvo Pharmaceuticals (Canada)","funders":"","keywords":"Ritanserin; Ketanserin; Agonist; Sumatriptan; Receptor; 5-HT1 receptor; Pharmacology; Neuroscience; Medicine; 5-HT receptor; Psychology; Serotonin; Internal medicine; Metabotropic receptor","authors":[{"name":"Abdelmalik Slassi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06235930049249711,"gpt":0.3852375655280254,"spread":0.3228782650355283,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009890608,0.0007521219,0.0009295408,0.0009210948,0.0001834904,0.0007245429,0.0006389043,0.001042706,0.004397496],"category_scores_gemma":[0.0007399046,0.0002759468,0.0006400799,0.000884284,0.0005083338,0.0009687708,0.0005889427,0.002165184,0.001356764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003990278,"about_ca_system_score_gemma":0.0005979443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005458429,"about_ca_topic_score_gemma":0.001134541,"domain_scores_codex":[0.999732,0.00006243036,0.00003991377,0.00005854101,0.00007010579,0.00003706631],"domain_scores_gemma":[0.9993712,0.0002471121,0.0001138354,0.00002884179,0.0001586713,0.00008020039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007309649,0.0004651549,0.0006309171,0.009567217,0.0001708578,0.0004771543,0.0001592702,0.0008091001,0.02323845,0.006978157,0.01791077,0.938862],"study_design_scores_gemma":[0.0002678781,0.002279752,0.004845287,0.001474738,0.0006808034,0.002871619,0.0001711696,0.001185595,0.01178006,0.006566307,0.9678051,0.00007172191],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002121649,0.9923644,0.00142235,0.001335546,0.000313349,0.00001396125,0.00005699467,0.00003118383,0.002340554],"genre_scores_gemma":[0.01214805,0.9810107,0.002501763,0.001574405,0.001135018,0.00003293836,0.0001637016,0.000006333889,0.001426994],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004397496,"threshold_uncertainty_score":0.01471102,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2318234238","doi":"10.2174/1568026614666140202204602","title":"Fluorinated Mechanism-Based Inhibitors: Common Themes and Recent Developments","year":2014,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Synthesis and properties of polymers","field":"Materials Science","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Mechanism (biology); Computational biology; Computer science; Biology; Epistemology; Philosophy","authors":[{"name":"Christina Tysoe","is_ca":false},{"name":"Stephen G. Withers","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05774321393578364,"gpt":0.335379141755068,"spread":0.2776359278192844,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00095925,0.0007963489,0.001112166,0.002378,0.0002884004,0.001409537,0.001026338,0.001114668,0.003482742],"category_scores_gemma":[0.000754185,0.0004375093,0.0004615772,0.002766287,0.000744919,0.002429683,0.0007681634,0.001924585,0.002028591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006940875,"about_ca_system_score_gemma":0.0008265085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005503167,"about_ca_topic_score_gemma":0.0009988905,"domain_scores_codex":[0.9997543,0.00003248408,0.00002927419,0.00005450092,0.00009862067,0.00003093926],"domain_scores_gemma":[0.999546,0.0002089157,0.00007587554,0.00001488676,0.0001095256,0.00004478617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009751855,0.0001575632,0.0002500735,0.01903083,0.00006695509,0.0003816895,0.0001901249,0.0006937837,0.006678266,0.01476499,0.0169358,0.9407525],"study_design_scores_gemma":[0.0000134429,0.0001701336,0.0004528056,0.001743541,0.00005364198,0.001326415,0.00009446713,0.000186985,0.002032977,0.003216856,0.9906853,0.00002342194],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002708994,0.9973868,0.0003521299,0.0002965316,0.0001575269,0.000007373126,0.00001455254,0.00001028853,0.001503853],"genre_scores_gemma":[0.001547361,0.996761,0.0003979453,0.0001950508,0.0002051689,0.000008656206,0.00002446705,0.000002472186,0.0008579191],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003482742,"threshold_uncertainty_score":0.01165086,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2009266771","doi":"10.2174/156802611795429176","title":"Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?","year":2011,"lang":"en","type":"article","venue":"Current Topics in Medicinal Chemistry","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Discovery Centre","funders":"Broad Institute; Novartis Foundation","keywords":"Phenotypic screening; Disease; Phenotype; Computational biology; Medicine; Data science; Computer science; Biology; Genetics; Internal medicine; Gene","authors":[{"name":"Ian H. Gilbert","is_ca":true},{"name":"Didier Leroy","is_ca":false},{"name":"Julie A. Frearson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.4963976006319916,"gpt":0.4357863922136876,"spread":0.06061120841830392,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007793342,0.0006217331,0.001966231,0.00174498,0.0003603278,0.002397643,0.001068373,0.001451541,0.007086161],"category_scores_gemma":[0.01272634,0.0002548006,0.0007251232,0.001810029,0.001676716,0.003821164,0.001215374,0.001186517,0.00153071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009008406,"about_ca_system_score_gemma":0.001059896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005125534,"about_ca_topic_score_gemma":0.0007878382,"domain_scores_codex":[0.9963157,0.00182065,0.0001301325,0.0002492703,0.001309588,0.0001746885],"domain_scores_gemma":[0.9933406,0.004646708,0.0006602925,0.0003490907,0.0007627591,0.0002405956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000608066,0.0005595823,0.01570229,0.004331582,0.0004015306,0.001475999,0.0003479053,0.02319198,0.009401291,0.1675027,0.02285948,0.7536176],"study_design_scores_gemma":[0.0007348551,0.006894544,0.03503815,0.002585208,0.0007866773,0.005443169,0.003354424,0.09806523,0.02747891,0.6435801,0.1756532,0.0003855849],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1347176,0.1154264,0.5141719,0.1021235,0.002802971,0.001594009,0.001525464,0.001295694,0.1263424],"genre_scores_gemma":[0.7559677,0.08698203,0.1247883,0.01042137,0.001736047,0.0009853467,0.0006789909,0.0002199692,0.0182202],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007793342,"threshold_uncertainty_score":0.0412156,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2005358308","doi":"10.2174/156802609789630839","title":"Peptide Mediated siRNA Delivery","year":2009,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Peptide; Chemistry; Computational biology; Biology; Biochemistry","authors":[{"name":"Mousa Jafari","is_ca":true},{"name":"P. Chen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04327762646527263,"gpt":0.3440909782378076,"spread":0.300813351772535,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002192793,0.0006669244,0.0006099572,0.0006640542,0.0001783985,0.0005214026,0.0005624761,0.0006516044,0.001432297],"category_scores_gemma":[0.0001549271,0.0001653777,0.0002224497,0.0004474647,0.0002584732,0.0005023085,0.000420085,0.0006756593,0.002088126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004529838,"about_ca_system_score_gemma":0.0003066144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002918903,"about_ca_topic_score_gemma":0.0003150579,"domain_scores_codex":[0.999846,0.00002255527,0.00001453514,0.00004189106,0.0000575616,0.0000174079],"domain_scores_gemma":[0.9999588,0.00001054864,0.00001053943,0.00000255485,0.00001320251,0.000004472063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007930829,0.00009334682,0.0001693526,0.005647623,0.00006686113,0.0009936646,0.0001145911,0.0006945668,0.5075925,0.008945485,0.006964436,0.4686382],"study_design_scores_gemma":[0.00003405359,0.0004146205,0.0006318353,0.0003880545,0.0000739385,0.004478594,0.00003802712,0.0007191974,0.4387843,0.00121708,0.5531832,0.00003705581],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02160581,0.9011905,0.03362494,0.0006011962,0.0009622427,0.0002772829,0.0002945208,0.0004168679,0.04102657],"genre_scores_gemma":[0.117602,0.8198123,0.02498707,0.001013843,0.0003075933,0.0003445191,0.000487055,0.0000488142,0.03539687],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001432297,"threshold_uncertainty_score":0.004791498,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2169673925","doi":"10.2174/1568026611313010004","title":"The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs","year":2013,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Wellcome Trust; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Allosteric regulation; G protein-coupled receptor; Chemistry; Fatty acid; Computational biology; Biochemistry; Combinatorial chemistry; Biology; Receptor","authors":[{"name":"Brian D. Hudson","is_ca":false},{"name":"Trond Ulven","is_ca":false},{"name":"Graeme Milligan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03752317418301737,"gpt":0.3281426430285333,"spread":0.2906194688455159,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003671357,0.0006017241,0.0009126738,0.001321559,0.0002485204,0.0006663628,0.0006631372,0.0008045975,0.003421271],"category_scores_gemma":[0.0003469892,0.0002076735,0.0004019189,0.001127918,0.0003937206,0.0009189962,0.0005500365,0.001651158,0.002069456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004912967,"about_ca_system_score_gemma":0.0004853956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004621617,"about_ca_topic_score_gemma":0.001050454,"domain_scores_codex":[0.9998838,0.00001914728,0.00001053196,0.00002020875,0.00004848428,0.00001780899],"domain_scores_gemma":[0.9999014,0.00004373009,0.00001463196,0.000003874831,0.00002422925,0.00001211173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008881307,0.0001107263,0.000125654,0.01039829,0.0000570618,0.0003262322,0.0000731008,0.0007152333,0.0109097,0.008981898,0.01867704,0.9495363],"study_design_scores_gemma":[0.00002667375,0.0001736206,0.0005729448,0.001558176,0.00005541765,0.001547927,0.00005276192,0.0002075089,0.002576091,0.002911923,0.9902962,0.00002080041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005900643,0.9956298,0.0004631121,0.0003797896,0.000213926,0.000007956371,0.0000257495,0.00001880472,0.002670867],"genre_scores_gemma":[0.00234484,0.9955165,0.0004192342,0.0002597268,0.0001381832,0.000009952861,0.00003581054,0.000002344675,0.001273478],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003421271,"threshold_uncertainty_score":0.01144528,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2402298570","doi":"10.2174/1568026615666150701115012","title":"Nuclear Targeting of Gold Nanoparticles for Improved Therapeutics","year":2015,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":28,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Nanomedicine; Colloidal gold; Cancer therapy; Nanotechnology; Cancer; Cancer research; DNA damage; Cytoplasm; Radiation therapy; Nucleus; Cancer cell; Chemistry; Nanoparticle; Computational biology; Medicine; DNA; Biology; Cell biology; Materials science; Biochemistry; Internal medicine","authors":[{"name":"Celina Yang","is_ca":true},{"name":"Devika B. Chithrani","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07793156887213819,"gpt":0.3575811981921471,"spread":0.2796496293200089,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002775275,0.0006157104,0.0006694079,0.001007052,0.000191493,0.0005317899,0.0004386749,0.0009366735,0.001439496],"category_scores_gemma":[0.0001682238,0.0002695305,0.000399544,0.000587426,0.000331576,0.0007206062,0.0005328889,0.0008998755,0.001301091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004857231,"about_ca_system_score_gemma":0.0004307822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005527723,"about_ca_topic_score_gemma":0.0008151904,"domain_scores_codex":[0.9998808,0.00002015872,0.000009579891,0.00002427639,0.00004695485,0.00001822822],"domain_scores_gemma":[0.9999548,0.00001389183,0.000008369507,0.00000274321,0.00001546902,0.000004679143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009374312,0.0001413102,0.0001805833,0.01936909,0.0001010932,0.0009417326,0.0002396475,0.00150465,0.174606,0.02508917,0.02187647,0.7558565],"study_design_scores_gemma":[0.00001805774,0.0002033042,0.0004668091,0.0008835834,0.00006812684,0.002040352,0.00005753462,0.0007940637,0.04749374,0.003231009,0.9447118,0.00003159231],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002108251,0.9897738,0.002671063,0.000354876,0.0003016356,0.00001715524,0.00002049725,0.00003377657,0.004718948],"genre_scores_gemma":[0.01877108,0.9723843,0.002928637,0.0003783057,0.0002111452,0.00003464617,0.00005503299,0.00001062096,0.005226185],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001439496,"threshold_uncertainty_score":0.004815519,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2336363203","doi":"10.2174/1568026616666160413142028","title":"Function and Chemotypes of Human Hsp70 Chaperones","year":2016,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":27,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Chaperone (clinical); Hsp70; Endoplasmic reticulum; Cell biology; Mitochondrion; Biology; Protein folding; Cytosol; Programmed cell death; Hsp90; Drug discovery; Heat shock protein; Cancer cell; Computational biology; Apoptosis; Cancer; Bioinformatics; Biochemistry; Medicine; Genetics; Enzyme","authors":[{"name":"Liza Shrestha","is_ca":false},{"name":"Jason C. Young","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07019045968782686,"gpt":0.3993152912579746,"spread":0.3291248315701477,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001827205,0.0005684202,0.0006063522,0.001596549,0.0001367239,0.0004362866,0.0004423313,0.000326005,0.002168211],"category_scores_gemma":[0.0002650688,0.0001549632,0.000337167,0.00164601,0.0002579417,0.0005293144,0.0003938141,0.00074673,0.002248101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003167789,"about_ca_system_score_gemma":0.0003416898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005386776,"about_ca_topic_score_gemma":0.0006974875,"domain_scores_codex":[0.9999081,0.00001178275,0.00001059769,0.00002181372,0.00003470411,0.00001305295],"domain_scores_gemma":[0.9999319,0.00001804102,0.00001652467,0.000003563597,0.00001954964,0.00001033352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000169232,0.0001022196,0.0005220245,0.01101468,0.00009557371,0.0002293781,0.0000701916,0.001169386,0.02609429,0.006732642,0.01576887,0.9380314],"study_design_scores_gemma":[0.00002588253,0.0002823735,0.002631726,0.001209722,0.0001051265,0.001986437,0.00004851021,0.000337001,0.01401519,0.002745854,0.9765767,0.00003545172],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002142864,0.9929034,0.0005551183,0.0001851732,0.0001050502,0.00001064391,0.0001571763,0.00002840711,0.003912243],"genre_scores_gemma":[0.01243748,0.9837209,0.0007731639,0.0001901056,0.0001008377,0.00001934677,0.0002267622,0.000005994225,0.002525432],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002168211,"threshold_uncertainty_score":0.007253408,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2160380996","doi":"10.2174/1568026614666140118213915","title":"Flow Chemistry to Control the Synthesis of Nano and Microparticles for Biomedical Applications","year":2014,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Innovative Microfluidic and Catalytic Techniques Innovation","field":"Engineering","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Nanotechnology; Microfluidics; Nano-; Nanoparticle; Flow chemistry; Microsystem; Chemistry; Materials science; Catalysis; Organic chemistry","authors":[{"name":"Natalia Hassan","is_ca":false},{"name":"Felipe Oyarzún-Ampuero","is_ca":false},{"name":"Pablo Lara","is_ca":false},{"name":"Simón Guerrero","is_ca":true},{"name":"Valérie Cabuil","is_ca":false},{"name":"Ali Abou‐Hassan","is_ca":false},{"name":"Marcelo J. Kogan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02131315098674379,"gpt":0.312184616119099,"spread":0.2908714651323552,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008132264,0.001169613,0.000754867,0.001920779,0.0003240368,0.000659007,0.000662472,0.001089304,0.002376371],"category_scores_gemma":[0.0004328972,0.000441534,0.00053354,0.001254399,0.0008725421,0.001555946,0.0006073589,0.001930941,0.002261817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007116203,"about_ca_system_score_gemma":0.0006749331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005768267,"about_ca_topic_score_gemma":0.0007844107,"domain_scores_codex":[0.9997075,0.00003325099,0.00002273889,0.00007693715,0.0001298485,0.00002961454],"domain_scores_gemma":[0.9998293,0.00007382261,0.00003186298,0.0000121456,0.00004072337,0.00001213398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005397893,0.0002226226,0.000226095,0.01422832,0.00009604704,0.0003032479,0.0001449901,0.001657559,0.1108065,0.0302947,0.01091281,0.8310532],"study_design_scores_gemma":[0.00002653007,0.0002514924,0.000483054,0.0009664005,0.0000739521,0.001079752,0.00004237278,0.001030964,0.07019916,0.004549346,0.9212359,0.00006104742],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001783196,0.9700493,0.01837043,0.000547447,0.0008913777,0.0000867039,0.00004557451,0.00009631622,0.008129694],"genre_scores_gemma":[0.01669873,0.9533572,0.01866364,0.0009674577,0.0006738033,0.0001510671,0.0001064795,0.00003882366,0.009342903],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002376371,"threshold_uncertainty_score":0.007949769,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}