{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":170,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":170,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"19a072a51efa","filters":{"venue":"Environmental and Molecular Mutagenesis"}},"results":[{"id":"W2109112922","doi":"10.1002/em.20357","title":"The social environment and the epigenome","year":2007,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":537,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Douglas Mental Health University Institute; Douglas College; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Epigenome; Epigenetics; DNA methylation; Biology; Chromatin; Epigenomics; Genetics; Epigenesis; Cellular Aging; DNA; Evolutionary biology; Gene; Gene expression; Telomere","authors":[{"name":"Moshe Szyf","is_ca":true},{"name":"Patrick O. McGowan","is_ca":true},{"name":"Michael J. Meaney","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01369838894466555,"gpt":0.2710463877275017,"spread":0.2573479987828361,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000388469,0.0009001761,0.000951634,0.001276427,0.0004357402,0.001211574,0.0007930392,0.001921055,0.004523257],"category_scores_gemma":[0.0005227936,0.0001659938,0.0002434347,0.001166403,0.00120815,0.001438287,0.0008248086,0.001184842,0.001969759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009768053,"about_ca_system_score_gemma":0.0009204701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00211797,"about_ca_topic_score_gemma":0.002845133,"domain_scores_codex":[0.9998341,0.00005077011,0.0000117277,0.00003067305,0.00005220165,0.00002055328],"domain_scores_gemma":[0.9998049,0.00008309552,0.00002586596,0.000007240696,0.00004127661,0.00003769653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000536487,0.00003922942,0.0007614106,0.004311674,0.00007163847,0.0005912285,0.0002596218,0.0003358354,0.0013977,0.01729897,0.04130306,0.933576],"study_design_scores_gemma":[0.000008365144,0.00004581787,0.003657889,0.001795453,0.00002960535,0.001974479,0.0002119674,0.00006875664,0.0003009339,0.01000201,0.9818859,0.00001883404],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003264457,0.9945869,0.0002081851,0.001277781,0.0003209625,0.000004584153,0.00001631068,0.000009553556,0.003249126],"genre_scores_gemma":[0.002526058,0.9945952,0.000160882,0.0003685416,0.0003095539,0.000009040268,0.00002210067,0.000001368461,0.002007267],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004523257,"threshold_uncertainty_score":0.01513177,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2072843401","doi":"10.1002/em.20406","title":"Genotoxicity, cytotoxicity, and reactive oxygen species induced by single‐walled carbon nanotubes and C<sub>60</sub> fullerenes in the FE1‐Muta™Mouse lung epithelial cells","year":2008,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Radiation Therapy and Dosimetry","field":"Medicine","cited_by":372,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Genotoxicity; Reactive oxygen species; Comet assay; Carbon black; Molecular biology; Oxygen; Chemistry; DNA damage; Cytotoxicity; Biophysics; Biology; Biochemistry; Toxicity; In vitro; DNA; Organic chemistry","authors":[{"name":"Nicklas Raun Jacobsen","is_ca":false},{"name":"Giulio Pojana","is_ca":false},{"name":"Paul A. White","is_ca":true},{"name":"Peter Möller","is_ca":false},{"name":"Corey A. Cohn","is_ca":false},{"name":"Karen Smith Korsholm","is_ca":false},{"name":"Ulla Vogel","is_ca":false},{"name":"Antonio Marcomini","is_ca":false},{"name":"Steffen Loft","is_ca":false},{"name":"Håkan Wallin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009185589233210712,"gpt":0.1947397128199218,"spread":0.1855541235867111,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001492821,0.000362165,0.0002623241,0.0002600825,0.0001489693,0.0001677586,0.0001167399,0.0003487923,0.000566016],"category_scores_gemma":[0.0001223541,0.0001394195,0.0002640585,0.000181675,0.0001730864,0.0001459668,0.0001332814,0.0001943602,0.0001605117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000193503,"about_ca_system_score_gemma":0.000145502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001079301,"about_ca_topic_score_gemma":0.001308766,"domain_scores_codex":[0.9998206,0.00003644634,0.00001996817,0.00003191835,0.00006266784,0.00002830151],"domain_scores_gemma":[0.9998592,0.00003551591,0.0000412447,0.00001270352,0.00003469163,0.00001657005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009145486,0.00001543955,0.0004456933,0.00003167801,0.000007742093,0.00004143501,0.00001478754,0.00009785547,0.9986072,0.00001675827,0.00001112219,0.0006188013],"study_design_scores_gemma":[0.000004471043,0.0005606279,0.00731081,0.000004551546,0.00002023036,0.0001423224,0.00002449657,0.000304559,0.9912471,0.00001803304,0.0003589357,0.00000383649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974369,0.001104723,0.0006998325,0.00002095619,0.00001001655,0.00001568929,0.0001684564,0.00001583014,0.0005276696],"genre_scores_gemma":[0.9959559,0.001256588,0.001052827,0.00003694984,0.000008754924,0.00003657339,0.0004835362,0.000006756873,0.001162119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001079301,"threshold_uncertainty_score":0.002146065,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2037797217","doi":"10.1002/em.20347","title":"Epigenetic control of plant stress response","year":2007,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Plant Molecular Biology Research","field":"Agricultural and Biological Sciences","cited_by":347,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Lethbridge","funders":"","keywords":"Epigenetics; Biology; Genetics; DNA methylation; Organism; Mendelian inheritance; Gene; Fight-or-flight response; Population; Epigenesis; Histone; Evolutionary biology; Computational biology; Gene expression","authors":[{"name":"Alex Boyko","is_ca":true},{"name":"Igor Kovalchuk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02151295585658355,"gpt":0.2535031564074447,"spread":0.2319902005508611,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002403636,0.000522596,0.0007136858,0.0009848474,0.0001951487,0.0004437873,0.0006018262,0.0006745234,0.001557374],"category_scores_gemma":[0.0002059043,0.0001772403,0.0001993619,0.0008672614,0.0003991821,0.0006738311,0.0003852307,0.0007052742,0.001380896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005070391,"about_ca_system_score_gemma":0.0004519052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005979788,"about_ca_topic_score_gemma":0.001011944,"domain_scores_codex":[0.9999141,0.00001485406,0.000009380121,0.00001923955,0.00003303825,0.000009376508],"domain_scores_gemma":[0.9999264,0.00002425056,0.0000140811,0.000003823277,0.00002184162,0.000009553194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006045146,0.00004062422,0.0003489986,0.008138665,0.00005646423,0.0003812953,0.00009153344,0.0006981444,0.01484018,0.0063735,0.01335278,0.9556174],"study_design_scores_gemma":[0.00001860706,0.00008200342,0.003331223,0.001474608,0.00006122304,0.002678513,0.00008865229,0.0002209515,0.004476887,0.005028531,0.9825174,0.00002132699],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004727431,0.9969427,0.0003865743,0.0002356191,0.0001558017,0.000004114995,0.00001226851,0.00001303901,0.001777074],"genre_scores_gemma":[0.00288841,0.9953506,0.0002908445,0.0001258439,0.0001492217,0.000006795974,0.00002138955,0.000001697236,0.001165156],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001557374,"threshold_uncertainty_score":0.005209982,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2028098070","doi":"10.1002/em.10192","title":"Methylated trivalent arsenicals as candidate ultimate genotoxic forms of arsenic: Induction of chromosomal mutations but not gene mutations","year":2003,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":200,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"University of British Columbia","keywords":"Sister chromatid exchange; Clastogen; Mutagen; Chemistry; Carcinogen; Arsenic; Biochemistry; Genotoxicity; Biology; Molecular biology; Toxicity; DNA","authors":[{"name":"Andrew D. Kligerman","is_ca":false},{"name":"Carolyn L. Doerr","is_ca":false},{"name":"Alan H. Tennant","is_ca":false},{"name":"Karen Harrington‐Brock","is_ca":false},{"name":"James W. Allen","is_ca":false},{"name":"Ernest Winkfield","is_ca":false},{"name":"P. Poorman‐Allen","is_ca":false},{"name":"Bijit Kundu","is_ca":false},{"name":"Kunihiro Funasaka","is_ca":false},{"name":"Barbara C. Roop","is_ca":false},{"name":"Marc J. Mass","is_ca":false},{"name":"David M. DeMarini","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006892605537136371,"gpt":0.2228742854308111,"spread":0.2159816798936748,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001680317,0.0003453844,0.0002120026,0.0003545972,0.0001284125,0.000320192,0.0002359443,0.000377211,0.001101516],"category_scores_gemma":[0.0002133944,0.0001631509,0.0002105028,0.0002712738,0.0001943751,0.0002030665,0.000268273,0.0003000088,0.0002954344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002571194,"about_ca_system_score_gemma":0.0002009283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006597243,"about_ca_topic_score_gemma":0.001610746,"domain_scores_codex":[0.9997978,0.00005233119,0.00001751625,0.00003721828,0.00007125823,0.00002396735],"domain_scores_gemma":[0.9998467,0.00002319658,0.00003707418,0.00002002307,0.00004315586,0.00002987045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008491252,0.000006995015,0.0002613851,0.00003121095,0.000006207651,0.00003173576,0.00001152054,0.00006257994,0.9986544,0.00004066504,0.000006925313,0.0008014607],"study_design_scores_gemma":[0.000004329932,0.0003437164,0.001932203,0.000003323929,0.00001535952,0.0001621141,0.00002543544,0.0001935983,0.9965211,0.00003928024,0.0007562952,0.000003271778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920673,0.002029164,0.004129888,0.00007045592,0.00001887235,0.00005965943,0.0002970262,0.0000813263,0.0012461],"genre_scores_gemma":[0.9932371,0.001126479,0.002878647,0.00003233591,0.000005075142,0.00001644385,0.0003882055,0.0000170548,0.002298659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001101516,"threshold_uncertainty_score":0.003684938,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2087824865","doi":"10.1002/em.20025","title":"Folate, colorectal carcinogenesis, and DNA methylation: Lessons from animal studies","year":2004,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Carcinogenesis; Colorectal cancer; Animal studies; Biology; Neoplastic transformation; Carcinogen; Vitamin; Physiology; Cancer; Medicine; Internal medicine; Endocrinology; Cancer research; Genetics","authors":[{"name":"Young‐In Kim","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05022987031590767,"gpt":0.3536622378869392,"spread":0.3034323675710315,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004155277,0.0009328479,0.001535612,0.001442334,0.0004603116,0.001384112,0.00137552,0.00379414,0.001569034],"category_scores_gemma":[0.005091362,0.0004591461,0.000779431,0.001010122,0.004037412,0.003420034,0.001439168,0.006264545,0.0004484507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001532905,"about_ca_system_score_gemma":0.001656613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005959368,"about_ca_topic_score_gemma":0.006783449,"domain_scores_codex":[0.9991059,0.0003949277,0.00008548689,0.0001866837,0.0001663168,0.00006066497],"domain_scores_gemma":[0.9954329,0.003324341,0.0002187202,0.0003240046,0.0004725758,0.0002276324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001335424,0.0008781918,0.0167905,0.01037863,0.001081301,0.004146301,0.002313573,0.004050221,0.01247467,0.08319444,0.06590025,0.7974566],"study_design_scores_gemma":[0.0003092434,0.001953776,0.02653152,0.006744415,0.0008520078,0.005724263,0.00304767,0.002970415,0.006193567,0.301659,0.6437371,0.0002770787],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01172033,0.9046755,0.005813683,0.06954018,0.001634868,0.00002473249,0.0001462251,0.00006901579,0.006375475],"genre_scores_gemma":[0.05830836,0.9136111,0.004887214,0.01598055,0.00503544,0.00005270488,0.00009042433,0.00002790627,0.002006296],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005959368,"threshold_uncertainty_score":0.02197546,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2100026340","doi":"10.1002/em.20639","title":"Pulmonary response to surface‐coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study","year":2011,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":166,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Inflammatory response; microRNA; Gene; Acute-phase protein; Biology; Inflammation; Toxicology; Genetics; Immunology","authors":[{"name":"Sabina Halappanavar","is_ca":true},{"name":"Petra Jackson","is_ca":false},{"name":"Andrew Williams","is_ca":true},{"name":"Keld Alstrup Jensen","is_ca":false},{"name":"Karin Sørig ­Hougaard","is_ca":false},{"name":"Ulla Vogel","is_ca":false},{"name":"Carole L. Yauk","is_ca":true},{"name":"Håkan Wallin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01522031237362073,"gpt":0.2345722879219467,"spread":0.219351975548326,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001914417,0.0003460104,0.0003331822,0.0001937781,0.0001110687,0.0002491898,0.0001024564,0.0003608616,0.0008713047],"category_scores_gemma":[0.0001070114,0.000155676,0.0004058323,0.0001432783,0.0002530183,0.0001809675,0.0001699879,0.0003722175,0.0001722365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001593753,"about_ca_system_score_gemma":0.0001242749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001645701,"about_ca_topic_score_gemma":0.0003123403,"domain_scores_codex":[0.9998287,0.00002619865,0.00001109944,0.0000449961,0.00005334321,0.00003561162],"domain_scores_gemma":[0.9998775,0.00002293714,0.00003871323,0.0000116271,0.00002546546,0.00002372592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000651911,0.000007815456,0.0002197147,0.00001365938,0.000003009752,0.00001344861,0.000005547467,0.00001258129,0.9994174,0.000004752468,0.00000340134,0.0002335781],"study_design_scores_gemma":[0.000008550246,0.0006039921,0.01865355,0.000003168153,0.00002597017,0.0001599517,0.00004808268,0.0005962724,0.9794165,0.00002307554,0.000456286,0.000004668966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947456,0.001503146,0.002904424,0.00005389502,0.00002433506,0.00003710525,0.0002317286,0.00003623213,0.0004635997],"genre_scores_gemma":[0.9934793,0.0009628698,0.003168426,0.00009740433,0.00002191477,0.0001179518,0.0004208055,0.00001500199,0.001716435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008713047,"threshold_uncertainty_score":0.002914786,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2001341440","doi":"10.1002/em.1033","title":"Human DNA repair genes","year":2001,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Victoria","funders":"","keywords":"DNA repair; Biology; Genetics; Gene; Nucleotide excision repair; DNA damage; DNA mismatch repair; DNA; Human genome; DNA replication; Base excision repair; Genome","authors":[{"name":"A. Ronen","is_ca":true},{"name":"Barry W. Glickman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01231219010278062,"gpt":0.2525520100654138,"spread":0.2402398199626332,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002893787,0.001126311,0.001120543,0.00132299,0.0003286181,0.0007228894,0.001097238,0.001053459,0.01190949],"category_scores_gemma":[0.0003801853,0.0001761667,0.0003777863,0.001579666,0.0004885042,0.0006670837,0.0005824718,0.0009033275,0.02050933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005489418,"about_ca_system_score_gemma":0.000598598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001210809,"about_ca_topic_score_gemma":0.001106054,"domain_scores_codex":[0.9997554,0.00003337455,0.00001953371,0.00007478158,0.00008427836,0.00003256575],"domain_scores_gemma":[0.9998764,0.00003736471,0.00002191574,0.000009734626,0.00003855097,0.00001613003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008573787,0.00004491073,0.0004003317,0.00392795,0.00004386849,0.0005891327,0.00008177631,0.000236363,0.01185651,0.002835284,0.07478654,0.9051116],"study_design_scores_gemma":[0.000009792013,0.00003801435,0.0009569735,0.0005711825,0.00002504476,0.00254335,0.00002724726,0.00002342177,0.002583925,0.0008378286,0.9923739,0.00000932019],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009986588,0.9748536,0.002184197,0.0006220985,0.0005962942,0.00004425178,0.0006812168,0.0001794148,0.01984034],"genre_scores_gemma":[0.01079301,0.935113,0.003904995,0.001477058,0.0004065394,0.00009366426,0.002073496,0.00002675561,0.04611152],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01190949,"threshold_uncertainty_score":0.03984118,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2152488413","doi":"10.1002/em.21727","title":"Quantitative approaches for assessing dose–response relationships in genetic toxicology studies","year":2012,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Genotoxicity; Methyl methanesulfonate; Micronucleus test; Ethyl methanesulfonate; Toxicology; In vivo; Point of delivery; Risk assessment; Computational biology; Toxicogenomics; Biology; Mode of action; Pharmacology; Statistics; Genetics; Toxicity; Computer science; Mathematics; Medicine; Gene; Mutation; DNA repair; Gene expression; Internal medicine","authors":[{"name":"B. Bhaskar Gollapudi","is_ca":false},{"name":"George E. Johnson","is_ca":false},{"name":"Lya G. Soeteman‐Hernández","is_ca":false},{"name":"Lynn H. Pottenger","is_ca":false},{"name":"Kerry L. Dearfield","is_ca":false},{"name":"A. M. Jeffrey","is_ca":false},{"name":"Eric Julien","is_ca":false},{"name":"J.H. Kim","is_ca":false},{"name":"David P. Lovell","is_ca":false},{"name":"James T. MacGregor","is_ca":false},{"name":"Martha M. Moore","is_ca":false},{"name":"Jan van Benthem","is_ca":false},{"name":"Paul A. White","is_ca":true},{"name":"Errol Zeiger","is_ca":false},{"name":"V. Thybaud","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07167322889074622,"gpt":0.3091444765778238,"spread":0.2374712476870776,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05826218,0.003098424,0.002198389,0.008401251,0.0009027455,0.004214393,0.004834886,0.002759368,0.003749154],"category_scores_gemma":[0.08976141,0.001516753,0.00415356,0.006674727,0.002778669,0.003699378,0.003925761,0.005457199,0.001215828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00386463,"about_ca_system_score_gemma":0.002505282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002774932,"about_ca_topic_score_gemma":0.002997893,"domain_scores_codex":[0.9299042,0.04401202,0.004165734,0.005270491,0.01597943,0.0006681327],"domain_scores_gemma":[0.9098195,0.06353983,0.009988086,0.009754563,0.006556771,0.0003412405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000935673,0.002165002,0.03390214,0.01010456,0.003832944,0.0005828589,0.002094052,0.2426196,0.1630051,0.1382598,0.005345562,0.3971527],"study_design_scores_gemma":[0.0002347133,0.006255839,0.0361243,0.001387988,0.001875923,0.001445085,0.002142958,0.5006032,0.1240985,0.2532673,0.07156455,0.0009996033],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.006606056,0.001477207,0.9862592,0.0002290249,0.0000924218,0.001391709,0.0009738944,0.0006570149,0.002313451],"genre_scores_gemma":[0.1440459,0.002635199,0.8423073,0.0007632902,0.0001320261,0.005723249,0.001847274,0.0004541508,0.002091722],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.05826218,"threshold_uncertainty_score":0.3081236,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2129167503","doi":"10.1002/em.21870","title":"Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment","year":2014,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"Health Canada; National Centre for the Replacement, Refinement and Reduction of Animals in Research","keywords":"Ethyl methanesulfonate; Point of delivery; Toxicology; Biology; Methyl methanesulfonate; Computational biology; Statistics; Genetics; Mutation; Mathematics; Gene; DNA repair; Botany","authors":[{"name":"George E. Johnson","is_ca":false},{"name":"Lya G. Soeteman‐Hernández","is_ca":false},{"name":"B. Bhaskar Gollapudi","is_ca":false},{"name":"Owen Bodger","is_ca":false},{"name":"Kerry L. Dearfield","is_ca":false},{"name":"Robert H. Heflich","is_ca":false},{"name":"J. Gregory Hixon","is_ca":false},{"name":"David P. Lovell","is_ca":false},{"name":"James T. MacGregor","is_ca":false},{"name":"Lynn H. Pottenger","is_ca":false},{"name":"Chad M. Thompson","is_ca":false},{"name":"L. Abraham","is_ca":false},{"name":"V. Thybaud","is_ca":false},{"name":"Jennifer Y. Tanir","is_ca":false},{"name":"Errol Zeiger","is_ca":false},{"name":"Jan van Benthem","is_ca":false},{"name":"Paul A. White","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003434495291932194,"gpt":0.2281950977651703,"spread":0.2247606024732381,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0206393,0.001766546,0.001726222,0.006773866,0.0006612464,0.003158791,0.002698728,0.001382599,0.001848255],"category_scores_gemma":[0.07592719,0.0008815844,0.002576407,0.00409897,0.001538232,0.002416357,0.003583538,0.00438145,0.0006933794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001322532,"about_ca_system_score_gemma":0.001962616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002465857,"about_ca_topic_score_gemma":0.00246653,"domain_scores_codex":[0.9907867,0.003290195,0.0009124337,0.002052205,0.002753903,0.0002045603],"domain_scores_gemma":[0.9438908,0.03891214,0.007131158,0.005529004,0.00416742,0.0003695471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0005900967,0.000461834,0.09900249,0.003563602,0.001833535,0.001165707,0.001111155,0.4083287,0.03163172,0.1016242,0.00603283,0.3446543],"study_design_scores_gemma":[0.00007435612,0.0009886397,0.03672123,0.0005751476,0.0003843219,0.001216306,0.0005567294,0.7783782,0.02873812,0.1240639,0.02797336,0.0003296553],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.0198575,0.0006288915,0.9760712,0.00009713371,0.0000576999,0.0002164253,0.001098305,0.0006778268,0.001294998],"genre_scores_gemma":[0.2905812,0.001305633,0.7001156,0.0002329478,0.00008215374,0.001090348,0.004605011,0.0005140287,0.001473051],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0206393,"threshold_uncertainty_score":0.1091524,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2011006143","doi":"10.1002/em.20361","title":"Epigenetic changes and nontargeted radiation effects—Is there a link?","year":2008,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Lethbridge","funders":"National Aeronautics and Space Administration; U.S. Department of Energy","keywords":"Epigenetics; Link (geometry); Biology; Genetics; Computational biology; Bioinformatics; Computer science; Gene; Computer network","authors":[{"name":"Olga Kovalchuk","is_ca":true},{"name":"Janet E. Baulch","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006808058802183216,"gpt":0.2397708570342835,"spread":0.2329627982321003,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004078042,0.0007133564,0.001544215,0.001185934,0.0003017932,0.0008965757,0.000978475,0.001603682,0.003173588],"category_scores_gemma":[0.0006286678,0.0001957807,0.0003827786,0.001388211,0.001098272,0.001958903,0.0005551372,0.001414954,0.001273385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005828928,"about_ca_system_score_gemma":0.0006910326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008593222,"about_ca_topic_score_gemma":0.001225917,"domain_scores_codex":[0.9998311,0.00003944564,0.00001871318,0.00003569698,0.00005877405,0.00001630113],"domain_scores_gemma":[0.9996276,0.0002119283,0.00004426713,0.00001492138,0.0000734955,0.00002784894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007439172,0.00008500744,0.000532592,0.01198266,0.0001072569,0.00125483,0.0001936764,0.0003745636,0.005552479,0.007472279,0.01540347,0.9569668],"study_design_scores_gemma":[0.00001684871,0.000179574,0.003668329,0.00289721,0.0001192307,0.007712948,0.0003406084,0.0001408031,0.002312458,0.01133011,0.971249,0.00003280422],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002014318,0.9980505,0.0002207012,0.0004304905,0.0002506888,0.000002239584,0.000004860489,0.000005688354,0.0008334757],"genre_scores_gemma":[0.001494389,0.9967752,0.0001602925,0.0002895089,0.0002982833,0.000003879436,0.00000989678,0.000001280553,0.0009672862],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003173588,"threshold_uncertainty_score":0.01061672,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2072131879","doi":"10.1002/em.20300","title":"Increased mutant frequency by carbon black, but not quartz, in the <i>lacZ</i> and <i>cII</i> transgenes of muta<sup>™</sup>mouse lung epithelial cells","year":2007,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Mutagen; Molecular biology; Carcinogen; Mutation frequency; Chemistry; Carbon black; Pyrene; Mutant; Anthracene; DNA; Genotoxicity; Mutagenesis; Biochemistry; Biology; Toxicity; Organic chemistry; Gene","authors":[{"name":"Nicklas Raun Jacobsen","is_ca":false},{"name":"Anne Thoustrup Saber","is_ca":false},{"name":"Paul A. White","is_ca":true},{"name":"Peter Möller","is_ca":false},{"name":"Giulio Pojana","is_ca":false},{"name":"Ulla Vogel","is_ca":false},{"name":"Steffen Loft","is_ca":false},{"name":"John D. Gingerich","is_ca":true},{"name":"Lynda M. Soper","is_ca":true},{"name":"George R. Douglas","is_ca":true},{"name":"Håkan Wallin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003091798425453316,"gpt":0.1906950108919248,"spread":0.1876032124664715,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002549592,0.0005716736,0.0003686179,0.0006657109,0.0001514118,0.0003504698,0.0002371842,0.0005132902,0.001543623],"category_scores_gemma":[0.0002393888,0.0002957552,0.0004724967,0.0002564408,0.0003016085,0.0001652658,0.0002659652,0.000609228,0.0003313171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003395778,"about_ca_system_score_gemma":0.0001894241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001658976,"about_ca_topic_score_gemma":0.001451824,"domain_scores_codex":[0.9994864,0.00008416373,0.00005862031,0.0001320591,0.0001682126,0.00007043715],"domain_scores_gemma":[0.9995236,0.0001059542,0.0001716226,0.00006104739,0.00005826211,0.00007953013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003845902,0.000009267715,0.0002166807,0.000007402125,0.000004150233,0.00001459224,0.000005886139,0.00001660274,0.9994884,0.000010581,0.000004745015,0.0001832342],"study_design_scores_gemma":[0.000005293224,0.0003495383,0.0113106,0.000003123577,0.00001884869,0.0002040807,0.00001924732,0.0003791661,0.9872891,0.0000146238,0.0004017703,0.000004716892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964226,0.0004715165,0.002071786,0.00004114525,0.00001306435,0.00002285766,0.0004404477,0.00007253802,0.0004440413],"genre_scores_gemma":[0.9928824,0.0004216493,0.002608649,0.00003523376,0.000006124824,0.000045892,0.001084563,0.00004970026,0.002865728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001658976,"threshold_uncertainty_score":0.005163908,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1966413695","doi":"10.1002/em.20440","title":"Radiation‐induced bystander effects in vivo are epigenetically regulated in a tissue‐specific manner","year":2008,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Lethbridge","funders":"","keywords":"Bystander effect; In vivo; Biology; Cell biology; Genetics; Toxicology; Immunology","authors":[{"name":"Yaroslav Ilnytskyy","is_ca":true},{"name":"Igor Koturbash","is_ca":true},{"name":"Olga Kovalchuk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005224380016274432,"gpt":0.2056169711747948,"spread":0.2003925911585203,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001277565,0.000285741,0.0003288748,0.000234388,0.0001297174,0.000230865,0.0001253333,0.000237611,0.001896115],"category_scores_gemma":[0.0001198493,0.0001301765,0.0003022833,0.0001364,0.0001992695,0.0001631489,0.0002200136,0.0003615216,0.0003563697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001323372,"about_ca_system_score_gemma":0.0001105922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002205982,"about_ca_topic_score_gemma":0.0003753296,"domain_scores_codex":[0.9998815,0.00001956119,0.000006868182,0.00004561231,0.00002825014,0.00001811875],"domain_scores_gemma":[0.9998856,0.00001500384,0.0000463299,0.00002333233,0.00001808638,0.00001161672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003655547,0.000005984541,0.0003376696,0.00002043646,0.00000768376,0.00001703761,0.00001252921,0.00001358626,0.9986944,0.00001914503,0.00001136217,0.0008236234],"study_design_scores_gemma":[0.000007611348,0.0006766401,0.07036134,0.000009961988,0.00005393305,0.0003745162,0.00005494839,0.0002675049,0.9256777,0.00007457945,0.002434277,0.000006938405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987166,0.00408584,0.006270399,0.00005037345,0.0000378238,0.00005037873,0.0004444613,0.0001383488,0.001756355],"genre_scores_gemma":[0.9924038,0.001761213,0.001995533,0.00005398435,0.00001583021,0.00004916035,0.0006723836,0.00002630656,0.003021809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001896115,"threshold_uncertainty_score":0.006343126,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2121669201","doi":"10.1002/(sici)1098-2280(2000)35:3<253::aid-em11>3.0.co;2-j","title":"In vivo transgenic mutation assays","year":2000,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Victoria; Health Canada; York University","funders":"","keywords":"Mutant; In vivo; Biology; Transgene; Mutation; Gene; Genetics","authors":[{"name":"John A. Heddle","is_ca":true},{"name":"S.W. Dean","is_ca":false},{"name":"Takehiko Nohmi","is_ca":false},{"name":"Micha�l E. T. I. Boerrigter","is_ca":false},{"name":"Daniel A. Casciano","is_ca":false},{"name":"George R. Douglas","is_ca":true},{"name":"Barry W. Glickman","is_ca":true},{"name":"Nancy J. Gorelick","is_ca":false},{"name":"Jon C. Mirsalis","is_ca":false},{"name":"Hans-J�rg Martus","is_ca":false},{"name":"Thomas R. Skopek","is_ca":false},{"name":"Véronique Thybaud","is_ca":false},{"name":"Kenneth R. Tindall","is_ca":false},{"name":"Nobuhiro Yajima","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.002891850432670672,"gpt":0.1997215544804539,"spread":0.1968297040477833,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002142522,0.002239605,0.001438869,0.00321511,0.0008260065,0.00135957,0.001663062,0.002279677,0.0173798],"category_scores_gemma":[0.001007803,0.0009561435,0.001811603,0.001133872,0.0008880524,0.0009050881,0.001073558,0.004228835,0.009714204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009493216,"about_ca_system_score_gemma":0.000660483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0011871,"about_ca_topic_score_gemma":0.002400866,"domain_scores_codex":[0.9964799,0.0007271456,0.000397886,0.0007650472,0.001226678,0.0004033421],"domain_scores_gemma":[0.9976867,0.0004863057,0.0006225033,0.0004306008,0.0004416856,0.000332134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001964744,0.0002678719,0.0003675856,0.0002510075,0.00004533541,0.0001971614,0.00005926107,0.0003580849,0.9893991,0.001370213,0.002711889,0.004776033],"study_design_scores_gemma":[0.0001073827,0.001316927,0.001903772,0.00008387225,0.0001743271,0.001361754,0.00005947059,0.002301374,0.9476206,0.0009495984,0.04405769,0.00006318397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3188057,0.01087347,0.5015405,0.001694855,0.00245065,0.006663273,0.0577609,0.01745313,0.08275761],"genre_scores_gemma":[0.4631184,0.01525561,0.2105437,0.00182346,0.0003299834,0.007299673,0.07025711,0.004576294,0.2267959],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0173798,"threshold_uncertainty_score":0.05814117,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2155243157","doi":"10.1002/em.21776","title":"Diethylhexyl phthalate exposure impairs follicular development and affects oocyte maturation in the mouse","year":2013,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":123,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Guelph","funders":"","keywords":"Phthalate; Folliculogenesis; Oogenesis; Offspring; Biology; Endocrinology; Internal medicine; Oocyte; Xenoestrogen; Endocrine disruptor; Andrology; Follicular phase; Follicle; Endocrine system; Pregnancy; Lactation; Embryo; Chemistry; Medicine; Estrogen receptor; Genetics; Hormone","authors":[{"name":"Xifeng Zhang","is_ca":false},{"name":"Lianjun Zhang","is_ca":false},{"name":"Lan Li","is_ca":false},{"name":"Yanni Feng","is_ca":false},{"name":"Bo Chen","is_ca":false},{"name":"Jin‐Mei Ma","is_ca":false},{"name":"Evanna Huynh","is_ca":true},{"name":"Qinghua Shi","is_ca":false},{"name":"Massimo De Felici","is_ca":false},{"name":"Wei Shen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003689393769582231,"gpt":0.2254976029670357,"spread":0.2218082091974534,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002391885,0.0005190413,0.0003734501,0.001195131,0.0002558159,0.0003844428,0.0004118092,0.0007136614,0.001962963],"category_scores_gemma":[0.0002015438,0.0004684609,0.0006837184,0.0003939438,0.0003942977,0.0004580482,0.0003330405,0.001036752,0.0004303045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000425287,"about_ca_system_score_gemma":0.0003221446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001707075,"about_ca_topic_score_gemma":0.002452861,"domain_scores_codex":[0.9996068,0.00003856606,0.00003902402,0.0001354888,0.0001040518,0.00007623478],"domain_scores_gemma":[0.9997608,0.00002263702,0.00009474881,0.00002953278,0.00002389321,0.00006848102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006455726,0.0001992345,0.001981443,0.0000745086,0.0000219615,0.0001742072,0.00006017294,0.00009447188,0.9939803,0.0001346927,0.000108875,0.002524668],"study_design_scores_gemma":[0.0001392204,0.003846852,0.04372458,0.00005365697,0.0001311795,0.001178873,0.0001960864,0.0009911992,0.942225,0.0004033146,0.007076601,0.00003358328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883696,0.004337307,0.002620702,0.0003510388,0.00007223683,0.00009903423,0.002014335,0.0002031752,0.001932601],"genre_scores_gemma":[0.9759834,0.005509553,0.003053274,0.0003400505,0.00002812328,0.0002829293,0.00169672,0.00008289178,0.01302302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001962963,"threshold_uncertainty_score":0.006566763,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2046908575","doi":"10.1002/em.1017","title":"Evaluation of the rodent micronucleus assay by a 28‐day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)–Mammalian Mutagenicity Study Group (MMS)","year":2001,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Micronucleus test; Micronucleus; Genotoxicity; Mutagen; Dose; Toxicology; Pharmacology; Biology; Clastogen; Toxicity; Bone marrow; Carcinogen; Medicine; Immunology; Genetics; Internal medicine","authors":[{"name":"Shuichi Hamada","is_ca":false},{"name":"Sizuyo Sutou","is_ca":false},{"name":"Takeshi Morita","is_ca":false},{"name":"Akihiro Wakata","is_ca":false},{"name":"S. Asanami","is_ca":false},{"name":"Satoko Hosoya","is_ca":false},{"name":"Shigenari Ozawa","is_ca":false},{"name":"Koji Kondo","is_ca":false},{"name":"Madoka Nakajima","is_ca":false},{"name":"Hiroyasu Shimada","is_ca":false},{"name":"Koichi OSAWA","is_ca":false},{"name":"Yasushi Kondo","is_ca":false},{"name":"Norihide Asano","is_ca":false},{"name":"Seiichi Sato","is_ca":false},{"name":"Hironobu Tamura","is_ca":false},{"name":"Nobuhiro Yajima","is_ca":false},{"name":"R. Marshall","is_ca":false},{"name":"Catherine Moore","is_ca":false},{"name":"David H. Blakey","is_ca":true},{"name":"Leonard M. Schechtman","is_ca":false},{"name":"James L. Weaver","is_ca":false},{"name":"Dorothea K. Torous","is_ca":false},{"name":"Raymond Proudlock","is_ca":false},{"name":"Seiichi Ito","is_ca":false},{"name":"Chiaki Namiki","is_ca":false},{"name":"Makoto Hayashi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008957079695054318,"gpt":0.254864494822347,"spread":0.2459074151272926,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01488048,0.002871274,0.002503884,0.003280695,0.00141472,0.0007503261,0.002821005,0.002546184,0.002800884],"category_scores_gemma":[0.003772735,0.001223534,0.002580968,0.001391575,0.0009383247,0.000611509,0.001108705,0.001796582,0.001529092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00107137,"about_ca_system_score_gemma":0.004119972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002612968,"about_ca_topic_score_gemma":0.006987928,"domain_scores_codex":[0.9890521,0.003689426,0.002500465,0.001274303,0.003015134,0.0004684586],"domain_scores_gemma":[0.9909859,0.0007465419,0.001759717,0.001876937,0.004128164,0.0005027345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002571666,0.003413633,0.007129065,0.002305949,0.000428251,0.000186587,0.0003026946,0.001538023,0.929216,0.0005544394,0.003244963,0.04910882],"study_design_scores_gemma":[0.0009893929,0.0471894,0.03397566,0.0002268639,0.0008620602,0.0005263975,0.00008865423,0.001722877,0.8739889,0.0002097352,0.04002588,0.0001942071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4442891,0.0142551,0.3656005,0.000793661,0.001029326,0.13862,0.01582678,0.003051196,0.01653422],"genre_scores_gemma":[0.2516643,0.01097542,0.5337967,0.001059124,0.00027027,0.1409615,0.03625134,0.0004817215,0.0245397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01488048,"threshold_uncertainty_score":0.07869643,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1978119100","doi":"10.1002/em.20358","title":"The γ‐H2A.X: Is it just a surrogate marker of double‐strand breaks or much more?","year":2007,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Histone H2A; Histone; Histone code; Phosphorylation; Biology; Histone H3; Cell biology; DNA repair; Histone methylation; Histone H1; Histone methyltransferase; DNA; Genetics; Molecular biology; Nucleosome; Gene; DNA methylation; Gene expression","authors":[{"name":"Ismail Hassan Ismail","is_ca":true},{"name":"Michael J. Hendzel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03458626573478064,"gpt":0.3097376895520719,"spread":0.2751514238172912,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004913803,0.0005813158,0.001367976,0.001102863,0.0002499171,0.0006812065,0.0007808536,0.001190303,0.001840329],"category_scores_gemma":[0.0004193536,0.0002126545,0.00023036,0.001345509,0.0007656333,0.001371449,0.0003612359,0.001274023,0.002465585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006580264,"about_ca_system_score_gemma":0.0005507258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001233131,"about_ca_topic_score_gemma":0.001373684,"domain_scores_codex":[0.999882,0.00002051709,0.00001115948,0.00003081014,0.00004555212,0.000009934749],"domain_scores_gemma":[0.9997666,0.00008900947,0.00003962044,0.00000942797,0.00006924223,0.00002611033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001065443,0.00004117136,0.0006595759,0.008257344,0.00006452317,0.0003875064,0.00006706047,0.0002313976,0.01294075,0.006004038,0.02499073,0.9462494],"study_design_scores_gemma":[0.000009966312,0.00008502169,0.001580665,0.001045294,0.00005902415,0.002604333,0.00009702765,0.00007068281,0.003630918,0.002264801,0.988529,0.00002332315],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002036741,0.9980296,0.0002640288,0.0003456924,0.0001886963,0.00000187518,0.00001221771,0.000006016638,0.0009481465],"genre_scores_gemma":[0.001538955,0.996391,0.0003525182,0.0003039714,0.0001557358,0.000004056218,0.00002846392,0.000002399732,0.001222897],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001840329,"threshold_uncertainty_score":0.006156504,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2105230092","doi":"10.1002/em.21941","title":"Development of a toxicogenomics signature for genotoxicity using a dose‐optimization and informatics strategy in human cells","year":2015,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":101,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism","keywords":"Toxicogenomics; Genotoxicity; Signature (topology); Computational biology; Toxicology; Informatics; Biology; Computer science; Bioinformatics; Genetics; Medicine; Engineering; Toxicity; Gene; Internal medicine; Mathematics","authors":[{"name":"Heng‐Hong Li","is_ca":false},{"name":"Daniel R. Hyduke","is_ca":false},{"name":"Renxiang Chen","is_ca":false},{"name":"Pamela L. Heard","is_ca":false},{"name":"Carole L. Yauk","is_ca":true},{"name":"Jiri Aubrecht","is_ca":false},{"name":"Albert J. Fornace","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02723225711423558,"gpt":0.2628969040009153,"spread":0.2356646468866797,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009360398,0.0006373294,0.0007691742,0.0007241871,0.000315461,0.000763834,0.0004758475,0.0006859311,0.001338183],"category_scores_gemma":[0.0008391344,0.0003330428,0.0008607017,0.0009411272,0.0003852953,0.0003066804,0.0005612717,0.0008097073,0.0006788177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006104436,"about_ca_system_score_gemma":0.0006693728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001614752,"about_ca_topic_score_gemma":0.002820084,"domain_scores_codex":[0.9991154,0.0001462028,0.00007204171,0.0002947643,0.0003189442,0.00005255907],"domain_scores_gemma":[0.9996841,0.00007246664,0.00005651992,0.0000740805,0.00009912859,0.00001375909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001237301,0.00006774493,0.002337744,0.00009690307,0.00002871983,0.00004574532,0.0000463334,0.004028781,0.9810503,0.00017566,0.0001731132,0.01182516],"study_design_scores_gemma":[0.000006969028,0.0002767569,0.007568663,0.000009692235,0.000040083,0.0001168458,0.00005108455,0.008958008,0.9801387,0.0002565,0.002555853,0.00002086998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.6252495,0.001617342,0.3577356,0.0003836092,0.00008818362,0.0007447203,0.009432808,0.001593988,0.003154293],"genre_scores_gemma":[0.6932616,0.001982358,0.2874168,0.0003245366,0.00002240969,0.001353707,0.01168327,0.0002705292,0.00368481],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001614752,"threshold_uncertainty_score":0.004950345,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2994223600","doi":"10.1002/em.22351","title":"Quantitative Interpretation of Genetic Toxicity Dose‐Response Data for Risk Assessment and Regulatory Decision‐Making: Current Status and Emerging Priorities","year":2019,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"University of Toronto; Health Canada","funders":"Health Canada; Government of Canada","keywords":"Risk assessment; Interpretation (philosophy); Risk analysis (engineering); Current (fluid); Toxicity; Toxicology; Computational biology; Biology; Business; Computer science; Medicine; Engineering; Computer security","authors":[{"name":"Paul A. White","is_ca":true},{"name":"Alexandra S. Long","is_ca":true},{"name":"George E. Johnson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01025522023104827,"gpt":0.3015220984734578,"spread":0.2912668782424095,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1534534,0.002947777,0.005084497,0.00741435,0.001119619,0.01662186,0.01229007,0.00605464,0.008810018],"category_scores_gemma":[0.1259589,0.001290493,0.002617072,0.005871444,0.009442572,0.01428252,0.004865,0.009915724,0.003203535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007164763,"about_ca_system_score_gemma":0.0162778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007856732,"about_ca_topic_score_gemma":0.005998345,"domain_scores_codex":[0.9537994,0.02774081,0.002958485,0.002973666,0.01186343,0.00066427],"domain_scores_gemma":[0.7254999,0.1804602,0.01631137,0.01620052,0.05832637,0.003201672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0003518107,0.0005957662,0.004959461,0.008423799,0.0003739851,0.0001660744,0.0007720118,0.0170268,0.005079466,0.1766363,0.03444237,0.7511721],"study_design_scores_gemma":[0.0001786885,0.0007337415,0.00379832,0.01491525,0.000415241,0.0003670424,0.002629449,0.05304125,0.007736139,0.5135997,0.4019963,0.0005889356],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.008172506,0.2432011,0.6377535,0.0773887,0.003438893,0.0009263912,0.002886337,0.002410471,0.02382205],"genre_scores_gemma":[0.0897352,0.2225715,0.6607079,0.01305792,0.003721284,0.001651918,0.00402823,0.0009556545,0.00357039],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.1534534,"threshold_uncertainty_score":0.8115491,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3023202365","doi":"10.1002/em.22378","title":"A review on the 40th anniversary of the first regulation of drinking water disinfection by‐products","year":2020,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Water Treatment and Disinfection","field":"Environmental Science","cited_by":85,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Haloacetic acids; Environmental health; Public health; Toxicology; Population; Trihalomethane; Safe Drinking Water Act; Water treatment; Water disinfection; International agency; Environmental chemistry; Carcinogen; Chemistry; Environmental science; Medicine; Water quality; Biology; Environmental engineering; Ecology","authors":[{"name":"David M. DeMarini","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008745321750652745,"gpt":0.1940066043142824,"spread":0.1852612825636297,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001170302,0.001010811,0.001521946,0.003398881,0.0003412132,0.001569179,0.0009581726,0.001518747,0.0104703],"category_scores_gemma":[0.003086041,0.0003932726,0.001143827,0.003780058,0.0004142251,0.002007785,0.001028939,0.00199182,0.00426135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00125481,"about_ca_system_score_gemma":0.002970503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002263762,"about_ca_topic_score_gemma":0.003362877,"domain_scores_codex":[0.9989479,0.0001733174,0.0002199535,0.0001626622,0.0004267601,0.00006943762],"domain_scores_gemma":[0.9980043,0.0006228936,0.0003814218,0.00005712856,0.0007910671,0.0001432135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001539163,0.00004891049,0.0003164327,0.05923518,0.0002069937,0.0003431698,0.0001571261,0.0002570133,0.002305339,0.005091607,0.2515447,0.6803397],"study_design_scores_gemma":[0.000004164219,0.00003349497,0.0004333842,0.003412138,0.00005462549,0.0001530742,0.00001754624,0.00001130758,0.0001001126,0.0002657281,0.995507,0.000007323077],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001433087,0.9923192,0.0001301496,0.001408874,0.003544286,0.00001152426,0.0001511643,0.00001370402,0.002277775],"genre_scores_gemma":[0.0006561687,0.9933838,0.0001627671,0.001791888,0.001614935,0.00001413156,0.0002867537,0.000005403795,0.002084222],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0104703,"threshold_uncertainty_score":0.03502667,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2521171147","doi":"10.1002/em.22045","title":"Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations","year":2016,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Genetically Modified Organisms Research","field":"Agricultural and Biological Sciences","cited_by":82,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Context (archaeology); Genetic testing; Risk assessment; Risk analysis (engineering); Hazard; Hazard analysis; Adverse Outcome Pathway; Computational biology; Computer science; Biology; Bioinformatics; Medicine; Genetics; Engineering; Computer security; Reliability engineering","authors":[{"name":"Kerry L. Dearfield","is_ca":false},{"name":"B. Bhaskar Gollapudi","is_ca":false},{"name":"Jeffrey C. Bemis","is_ca":false},{"name":"R. Benz","is_ca":false},{"name":"George R. Douglas","is_ca":true},{"name":"Rosalie K. Elespuru","is_ca":false},{"name":"George E. Johnson","is_ca":false},{"name":"David Kirkland","is_ca":false},{"name":"Matthew J. LeBaron","is_ca":false},{"name":"Albert P. Li","is_ca":false},{"name":"Francesco Marchetti","is_ca":true},{"name":"Lynn H. Pottenger","is_ca":false},{"name":"Emiel Rorije","is_ca":false},{"name":"Jennifer Y. Tanir","is_ca":false},{"name":"Véronique Thybaud","is_ca":false},{"name":"Jan van Benthem","is_ca":false},{"name":"Carole L. Yauk","is_ca":true},{"name":"Errol Zeiger","is_ca":false},{"name":"Mirjam Luijten","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1573329686274239,"gpt":0.3290041565746377,"spread":0.1716711879472138,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007442217,0.001847078,0.001193768,0.002976886,0.001283093,0.005380601,0.005692661,0.005586777,0.005688118],"category_scores_gemma":[0.006345972,0.0007946471,0.001601101,0.001607679,0.005091111,0.006053375,0.003644357,0.003935424,0.001701027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003929361,"about_ca_system_score_gemma":0.005218579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006867735,"about_ca_topic_score_gemma":0.004466685,"domain_scores_codex":[0.9960189,0.001590648,0.0002265136,0.0006341946,0.00132547,0.0002042856],"domain_scores_gemma":[0.9962686,0.001822965,0.0003087875,0.0002887451,0.001082782,0.0002280305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00001992068,0.0000611975,0.0009741314,0.0002523582,0.00003326209,0.0006344127,0.0002657132,0.02131747,0.001108089,0.938441,0.00304237,0.03385006],"study_design_scores_gemma":[0.00002607886,0.000231824,0.000476566,0.0005939309,0.0000742824,0.001297884,0.0004229028,0.1135656,0.001544165,0.7842144,0.09744542,0.0001069243],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.003155051,0.01039784,0.9195921,0.01717232,0.0004806942,0.0004764099,0.0002643999,0.0002935675,0.04816755],"genre_scores_gemma":[0.2028005,0.0256521,0.7333304,0.00739742,0.00128549,0.002212457,0.0005824361,0.0001733826,0.02656573],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.007442217,"threshold_uncertainty_score":0.03935868,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2006960846","doi":"10.1002/em.20290","title":"Review of the literature examining the correlation among DNA microarray technologies","year":2007,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Computational biology; DNA; Correlation; Biology; Microarray; DNA microarray; Genetics; Gene; Mathematics; Gene expression","authors":[{"name":"Carole L. Yauk","is_ca":true},{"name":"Mathias Berndt","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01371660264302415,"gpt":0.2533629965108924,"spread":0.2396463938678683,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001504537,0.00110584,0.002333631,0.009086025,0.0004054192,0.001497174,0.001772896,0.001007289,0.005441187],"category_scores_gemma":[0.003837185,0.0004619822,0.0008476372,0.01273147,0.000462692,0.001791917,0.0005832273,0.0008334872,0.002655839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001099977,"about_ca_system_score_gemma":0.003168844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003151746,"about_ca_topic_score_gemma":0.004390825,"domain_scores_codex":[0.9991044,0.0001738706,0.0001896974,0.0001439216,0.000349084,0.0000389602],"domain_scores_gemma":[0.9970647,0.001694926,0.0003746921,0.00004541965,0.0007367259,0.00008370844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00007066726,0.00004656765,0.0005612256,0.06291047,0.0002003133,0.0005155966,0.0001176131,0.0003262987,0.00113142,0.001026933,0.03787125,0.8952215],"study_design_scores_gemma":[0.0000234671,0.0001511181,0.005630789,0.04313207,0.0009011986,0.003542087,0.0002038918,0.0001351807,0.0009251082,0.001503236,0.9438008,0.00005114138],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001583609,0.998547,0.0001600166,0.0002516019,0.0001531299,0.00000855504,0.00006172413,0.000008967555,0.0006505971],"genre_scores_gemma":[0.0004284438,0.9986797,0.0003733549,0.0001310333,0.00009975696,0.000009325995,0.00006275479,0.00000150321,0.0002141553],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009086025,"threshold_uncertainty_score":0.0182026,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2076442365","doi":"10.1002/em.20614","title":"New and emerging technologies for genetic toxicity testing","year":2010,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"National Centre for the Replacement, Refinement and Reduction of Animals in Research; Health and Environmental Sciences Institute","keywords":"Workgroup; Emerging technologies; Risk assessment; Hazard; Relevance (law); Risk analysis (engineering); Engineering ethics; Biology; Medicine; Computer science; Engineering; Political science; Computer security","authors":[{"name":"Anthony M. Lynch","is_ca":false},{"name":"Jennifer C. Sasaki","is_ca":false},{"name":"Rosalie K. Elespuru","is_ca":false},{"name":"David Jacobson‐Kram","is_ca":false},{"name":"Véronique Thybaud","is_ca":false},{"name":"Marlies De Boeck","is_ca":false},{"name":"Marilyn J. Aardema","is_ca":false},{"name":"Jiri Aubrecht","is_ca":false},{"name":"R. Benz","is_ca":false},{"name":"Stephen D. Dertinger","is_ca":false},{"name":"George R. Douglas","is_ca":true},{"name":"Paul A. White","is_ca":true},{"name":"Patricia A. Escobar","is_ca":false},{"name":"Albert J. Fornace","is_ca":false},{"name":"Masamitsu Honma","is_ca":false},{"name":"Russell Naven","is_ca":false},{"name":"James F. Rusling","is_ca":false},{"name":"Robert H. Schiestl","is_ca":false},{"name":"Richard M. Walmsley","is_ca":false},{"name":"Eiji Yamamura","is_ca":false},{"name":"Jan van Benthem","is_ca":false},{"name":"James H. Kim","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01350902799445928,"gpt":0.2610920055974567,"spread":0.2475829776029974,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002795401,0.002002484,0.001948605,0.006459418,0.0006398427,0.001960963,0.002083061,0.002752907,0.003837247],"category_scores_gemma":[0.001780563,0.0007108258,0.001168782,0.005303814,0.002197731,0.004542156,0.001403395,0.004538473,0.004004914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001975874,"about_ca_system_score_gemma":0.00214919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001873,"about_ca_topic_score_gemma":0.002208516,"domain_scores_codex":[0.9983847,0.0003124029,0.000164585,0.00028828,0.0007823891,0.00006760125],"domain_scores_gemma":[0.9985173,0.0008407359,0.0001515029,0.00007773797,0.0003456756,0.00006694744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004179234,0.000147221,0.0002325727,0.01392882,0.00006494579,0.0004469607,0.0001615902,0.001058255,0.00684757,0.03039921,0.02656174,0.9201093],"study_design_scores_gemma":[0.00001028105,0.00007084617,0.0002697012,0.001845417,0.00003262172,0.001448319,0.00007209084,0.0001855298,0.001847068,0.006681546,0.9875063,0.00003037047],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001359124,0.9926946,0.002451554,0.0005504098,0.000379517,0.00002131326,0.00002377845,0.00002746316,0.003715535],"genre_scores_gemma":[0.001102376,0.993294,0.002794033,0.0005040231,0.0002869814,0.00003536359,0.00004694575,0.000006304021,0.001929957],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006459418,"threshold_uncertainty_score":0.01478368,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2020284420","doi":"10.1002/em.20111","title":"Mutator phenotype in cancer: Timing and perspectives","year":2005,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Phenotype; Genetics; Mutagen; Cancer; Cancer cell; Mutation; Cell division; Gene; DNA repair; DNA; DNA replication; Cancer research; Cell","authors":[{"name":"Jason H. Bielas","is_ca":false},{"name":"Lawrence A. Loeb","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01801648320139104,"gpt":0.273705940647145,"spread":0.255689457445754,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009649387,0.001149781,0.002081711,0.002188592,0.0003638647,0.001160835,0.001570597,0.001985011,0.001727452],"category_scores_gemma":[0.0009465845,0.0003983763,0.0004191388,0.002407921,0.00172573,0.002361354,0.0007041358,0.002599093,0.002123327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0011671,"about_ca_system_score_gemma":0.0008374893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220853,"about_ca_topic_score_gemma":0.001593946,"domain_scores_codex":[0.9997398,0.00004683626,0.00003483527,0.00005825937,0.00009674619,0.00002348044],"domain_scores_gemma":[0.9993801,0.0003326133,0.00006592333,0.00002506786,0.0001405927,0.00005577217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001283608,0.00008835766,0.0004069642,0.008656802,0.0000578156,0.0005803038,0.00008849149,0.0008159969,0.003060708,0.01463608,0.02668945,0.9447906],"study_design_scores_gemma":[0.00001948969,0.0001457917,0.001140038,0.002043935,0.00005901621,0.002916698,0.00009259026,0.0001435882,0.001161015,0.008382289,0.9838659,0.00002971778],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007879597,0.9986808,0.0001253051,0.0002667629,0.0001961152,0.000001487807,0.000004901003,0.000005155704,0.0006407738],"genre_scores_gemma":[0.0006581885,0.998325,0.000133289,0.0002370801,0.0002108797,0.00000341621,0.000007444985,0.000001112742,0.0004235149],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002188592,"threshold_uncertainty_score":0.008467972,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2167868741","doi":"10.1002/em.20629","title":"Mutation spectrum in FE1‐MUTA<sup>TM</sup>Mouse lung epithelial cells exposed to nanoparticulate carbon black","year":2010,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Carbon black; Mutation; Cancer research; Genetics; Biology; Chemistry; Cell biology; Gene","authors":[{"name":"Nicklas Raun Jacobsen","is_ca":false},{"name":"Paul A. White","is_ca":true},{"name":"John D. Gingerich","is_ca":true},{"name":"Peter Möller","is_ca":false},{"name":"Anne Thoustrup Saber","is_ca":false},{"name":"George R. Douglas","is_ca":true},{"name":"Ulla Vogel","is_ca":false},{"name":"Håkan Wallin","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003321885921297164,"gpt":0.1973604073137462,"spread":0.1940385213924491,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001454585,0.0002347002,0.0002676175,0.0004250061,0.0001172692,0.0001821614,0.0001450133,0.0003812866,0.001222949],"category_scores_gemma":[0.0002040721,0.0001335366,0.0001797726,0.0001449153,0.0002209484,0.0001292629,0.00016201,0.0002932338,0.0002204136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000159877,"about_ca_system_score_gemma":0.00006177967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006134833,"about_ca_topic_score_gemma":0.0004832844,"domain_scores_codex":[0.9997515,0.00004043978,0.00002421256,0.00005377512,0.00009631593,0.00003378838],"domain_scores_gemma":[0.9997914,0.0000487675,0.00006418655,0.00002613524,0.00003689247,0.00003242821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005319713,0.00001184555,0.0004787287,0.000007287398,0.000001985106,0.00005755767,0.00001058072,0.00001652181,0.9990782,0.000008253916,0.000004063676,0.0002717208],"study_design_scores_gemma":[0.000003779516,0.0003112713,0.01476125,0.000002168358,0.000008035034,0.0005543415,0.0000349793,0.0002140669,0.9839143,0.00001353271,0.0001793594,0.000002888359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998673,0.0001787994,0.0005903576,0.00001644072,0.000003367596,0.000009134038,0.0001105856,0.00002354104,0.0003949082],"genre_scores_gemma":[0.9973218,0.0001974629,0.0009455328,0.00002041493,0.000002375496,0.00001721093,0.0002423044,0.0000107183,0.001242205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001222949,"threshold_uncertainty_score":0.004091144,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2980272132","doi":"10.1002/em.22338","title":"Mutation as a Toxicological Endpoint for Regulatory Decision‐Making","year":2019,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Mutagen; Germline mutation; Mutation; Somatic cell; Point mutation; Biology; Risk assessment; Genetics; Computational biology; Toxicology; Carcinogen; Bioinformatics; Gene; Computer science","authors":[{"name":"Robert H. Heflich","is_ca":false},{"name":"George E. Johnson","is_ca":false},{"name":"Andreas Zeller","is_ca":false},{"name":"Francesco Marchetti","is_ca":true},{"name":"George R. Douglas","is_ca":true},{"name":"Kristine L. Witt","is_ca":false},{"name":"B. Bhaskar Gollapudi","is_ca":false},{"name":"Paul A. White","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003895711030650943,"gpt":0.2341814464044724,"spread":0.2302857353738214,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1252865,0.001981278,0.002241543,0.004082221,0.001635067,0.01060775,0.00493609,0.005809559,0.004417969],"category_scores_gemma":[0.0796096,0.0006794319,0.002122837,0.002234785,0.004832034,0.005507657,0.003168473,0.006576877,0.001907626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005550467,"about_ca_system_score_gemma":0.01561488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004073553,"about_ca_topic_score_gemma":0.005063517,"domain_scores_codex":[0.9146004,0.05400427,0.003886529,0.003099276,0.02342797,0.000981446],"domain_scores_gemma":[0.9172276,0.04332264,0.009666585,0.007159211,0.02048593,0.002137999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001198747,0.001423218,0.02077757,0.00358731,0.0008109126,0.0006369617,0.00161722,0.1363453,0.03610445,0.4475608,0.04023892,0.3096986],"study_design_scores_gemma":[0.000334548,0.004044828,0.01149469,0.006258172,0.001076397,0.0007666817,0.002416843,0.2082883,0.03775457,0.4901865,0.23649,0.0008884961],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.04575622,0.01159838,0.7803001,0.0351601,0.003544537,0.002970133,0.001984711,0.001230097,0.1174557],"genre_scores_gemma":[0.4824537,0.004797271,0.4940353,0.008082891,0.0009187714,0.002371008,0.001152491,0.0002195048,0.005969051],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.1252865,"threshold_uncertainty_score":0.6625863,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2145364726","doi":"10.1002/em.21936","title":"Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response","year":2014,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":67,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"In vivo; Computational biology; Profiling (computer programming); Biology; Chemistry; Genetics; Computer science","authors":[{"name":"Sabina Halappanavar","is_ca":true},{"name":"Anne Thoustrup Saber","is_ca":false},{"name":"Nathalie Decan","is_ca":true},{"name":"Keld Alstrup Jensen","is_ca":false},{"name":"Dongmei Wu","is_ca":true},{"name":"Nicklas Raun Jacobsen","is_ca":false},{"name":"Charles Guo","is_ca":true},{"name":"Jacob L. Rogowski","is_ca":true},{"name":"Ismo Kalevi Koponen","is_ca":false},{"name":"Marcus Levin","is_ca":false},{"name":"Anne Mette Madsen","is_ca":false},{"name":"Rambabu Atluri","is_ca":false},{"name":"Valentinas Snitka","is_ca":false},{"name":"R. Birkedal","is_ca":false},{"name":"D.G. Rickerby","is_ca":false},{"name":"Andrew Williams","is_ca":true},{"name":"Håkan Wallin","is_ca":false},{"name":"Carole L. Yauk","is_ca":true},{"name":"Ulla Vogel","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02675902843632306,"gpt":0.245693108102572,"spread":0.2189340796662489,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003489597,0.0002910596,0.0005652689,0.00039591,0.0001454512,0.0005447982,0.0001503747,0.0004002748,0.0006585352],"category_scores_gemma":[0.0003969358,0.000214473,0.0004458882,0.0004255843,0.0002523334,0.0002520019,0.0001968093,0.0005277213,0.0002277033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000304464,"about_ca_system_score_gemma":0.0002270005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006036913,"about_ca_topic_score_gemma":0.0009054797,"domain_scores_codex":[0.9996251,0.00004999237,0.00001891639,0.0001413936,0.0000998252,0.00006474605],"domain_scores_gemma":[0.999694,0.00009562654,0.00008927461,0.00002632721,0.0000669175,0.00002788111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001256493,0.00002082664,0.00354216,0.00003854079,0.00001160854,0.00001174151,0.00001593405,0.00009558579,0.9951255,0.00002156,0.00001602218,0.0009748797],"study_design_scores_gemma":[0.00001621367,0.0007782786,0.3139679,0.0000209038,0.0001402915,0.0002151868,0.0002638843,0.004644406,0.6781442,0.0002817952,0.001506469,0.00002045375],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9886048,0.00151924,0.006187252,0.0001134022,0.00001727558,0.00005392448,0.002695625,0.00006574156,0.0007427486],"genre_scores_gemma":[0.9895466,0.001183475,0.004363445,0.0001501602,0.00001699785,0.0001283431,0.003216823,0.00003163782,0.001362531],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0006585352,"threshold_uncertainty_score":0.002209008,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1552431667","doi":"10.1002/em.21770","title":"Genotoxicity of nanomaterials: Refining strategies and tests for hazard identification","year":2013,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":62,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Genotoxicity; Toxicology; Computational biology; Risk analysis (engineering); Biotechnology; Biology; Medicine; Toxicity","authors":[{"name":"Stefan Pfuhler","is_ca":false},{"name":"Rosalie K. Elespuru","is_ca":false},{"name":"Marilyn J. Aardema","is_ca":false},{"name":"Shareen H. Doak","is_ca":false},{"name":"Erica Donner","is_ca":false},{"name":"Masamitsu Honma","is_ca":false},{"name":"Micheline Kirsch‐Volders","is_ca":false},{"name":"Robert Landsiedel","is_ca":false},{"name":"Mugimane G. Manjanatha","is_ca":false},{"name":"Tim Singer","is_ca":true},{"name":"James H. Kim","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01205865014833169,"gpt":0.2291747295021704,"spread":0.2171160793538388,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02766465,0.002812341,0.00261315,0.005024973,0.001323643,0.003859899,0.003398509,0.004121104,0.002254956],"category_scores_gemma":[0.009988817,0.001290696,0.001488813,0.00237258,0.005055327,0.007832624,0.003613891,0.004712667,0.00155216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004195718,"about_ca_system_score_gemma":0.004513499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002360393,"about_ca_topic_score_gemma":0.004342524,"domain_scores_codex":[0.984916,0.007300736,0.001096076,0.001511324,0.004689144,0.000486793],"domain_scores_gemma":[0.9932575,0.00232405,0.0005569817,0.0008322606,0.002824834,0.0002044015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003509102,0.0006085492,0.003691883,0.00865062,0.0001101412,0.0006175368,0.00216269,0.008202846,0.5262221,0.05051358,0.003854687,0.3950145],"study_design_scores_gemma":[0.00005459634,0.002892792,0.003229803,0.00213367,0.0001597251,0.001407255,0.003206491,0.009543544,0.6661217,0.07252372,0.2384492,0.0002775835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.0566385,0.1184829,0.778317,0.01626642,0.001559244,0.003940096,0.0007581408,0.0008114077,0.02322629],"genre_scores_gemma":[0.1583425,0.08756711,0.7314463,0.004366548,0.0003647396,0.002679287,0.0007088787,0.0003001537,0.01422459],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02766465,"threshold_uncertainty_score":0.1463064,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2140927372","doi":"10.1002/em.10185","title":"Development and characterization of a stable epithelial cell line from Muta™Mouse lung","year":2003,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"Health Canada; Ministère de l’Éducation, Gouvernement de l’Ontario; University of Guelph","keywords":"Molecular biology; Biology; Mutant; Mutagen; Micronucleus test; Transgene; Benzo(a)pyrene; Glutathione; Mutagenesis; Biochemistry; Chemistry; Carcinogen; Gene; Toxicity; Enzyme","authors":[{"name":"Paul A. White","is_ca":true},{"name":"George R. Douglas","is_ca":true},{"name":"John D. Gingerich","is_ca":true},{"name":"Craig L.J. Parfett","is_ca":true},{"name":"Philip S. Shwed","is_ca":true},{"name":"V.L. Seligy","is_ca":true},{"name":"Lynda M. Soper","is_ca":true},{"name":"Lynn Berndt","is_ca":true},{"name":"Janet Bayley","is_ca":true},{"name":"Shelley Wagner","is_ca":true},{"name":"Kathleen Pound","is_ca":true},{"name":"David H. Blakey","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003729919977075985,"gpt":0.1798196099415111,"spread":0.1760896899644351,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005412785,0.0004240265,0.0006482865,0.0005378682,0.0004549641,0.0008275775,0.0008983505,0.0004990553,0.001675321],"category_scores_gemma":[0.0003454834,0.0003035554,0.0005319171,0.0005150231,0.0002517221,0.0003420571,0.0004646411,0.001366838,0.002823491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003277349,"about_ca_system_score_gemma":0.00038632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00128173,"about_ca_topic_score_gemma":0.002055464,"domain_scores_codex":[0.999333,0.00007471691,0.00009402037,0.000119011,0.0002955139,0.00008374482],"domain_scores_gemma":[0.9995142,0.00007852559,0.00006267362,0.000104705,0.0001504244,0.00008951301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001747832,0.00003348036,0.0002316132,0.00002860676,0.000004506184,0.00006412545,0.00002542528,0.00003005932,0.9981237,0.0001065607,0.00008960288,0.001244816],"study_design_scores_gemma":[0.00002920111,0.0003729481,0.007109542,0.00002384705,0.00006748836,0.001515071,0.000090701,0.001951818,0.9650499,0.00008902561,0.0236799,0.00002048984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7901168,0.01009094,0.1680447,0.0010941,0.0004502168,0.001631843,0.0120322,0.001326022,0.01521322],"genre_scores_gemma":[0.821206,0.007603903,0.1077378,0.0005642314,0.0001350817,0.001476864,0.03280129,0.0003949792,0.02807982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001675321,"threshold_uncertainty_score":0.005604446,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2034282924","doi":"10.1002/em.10067","title":"Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cells","year":2002,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Guelph","funders":"Health Canada; U.S. Environmental Protection Agency","keywords":"Chemistry; Adduct; Carcinogen; DNA adduct; Breast milk; Heterocyclic amine; Mutagen; Ames test; DNA; Heterocyclic compound; Biochemistry; Biology; Bacteria; Organic chemistry; Genetics; Salmonella","authors":[{"name":"Patricia A. Thompson","is_ca":false},{"name":"David M. DeMarini","is_ca":false},{"name":"Fred F. Kadlubar","is_ca":false},{"name":"Gail Y. McClure","is_ca":false},{"name":"Lance R. Brooks","is_ca":false},{"name":"Bridgett L. Green","is_ca":false},{"name":"Manal Y. Fares","is_ca":false},{"name":"Angie Stone","is_ca":false},{"name":"P. David Josephy","is_ca":true},{"name":"Christine B. Ambrosone","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01404306657993664,"gpt":0.2287876930947323,"spread":0.2147446265147957,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002625535,0.0002565423,0.0001489961,0.00058402,0.0001259909,0.0002357952,0.0001562785,0.0003002958,0.001506179],"category_scores_gemma":[0.0006537336,0.0001863661,0.000129437,0.0002848841,0.0001891308,0.000113109,0.0002482445,0.0001550542,0.0004285598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009150046,"about_ca_system_score_gemma":0.0001052279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005284149,"about_ca_topic_score_gemma":0.0004974799,"domain_scores_codex":[0.9997454,0.00005364014,0.00002867292,0.00005111305,0.0000832138,0.0000378455],"domain_scores_gemma":[0.9994479,0.0001497628,0.0001385294,0.00005728704,0.0001393029,0.00006723258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005385214,0.00005240112,0.08717363,0.00008265399,0.0000342712,0.0007303656,0.0001302615,0.0000221732,0.9075915,0.00002576565,0.00005307866,0.003565338],"study_design_scores_gemma":[0.00003632186,0.0011127,0.5927982,0.00002680996,0.00008847428,0.008214328,0.0003266768,0.0002925484,0.3943942,0.00006547131,0.002634689,0.000009561758],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972836,0.001288063,0.0006986154,0.00003285309,0.000006595058,0.000008604244,0.0002351061,0.00001562801,0.0004309156],"genre_scores_gemma":[0.9960289,0.0009580825,0.0009992021,0.00004984313,0.00001132653,0.00001712172,0.000805779,0.000006903807,0.001122919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001506179,"threshold_uncertainty_score":0.005038679,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2980305786","doi":"10.1002/em.22339","title":"Application of the adverse outcome pathway framework to genotoxic modes of action","year":2019,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Adverse Outcome Pathway; Genotoxicity; Biology; Population; Computational biology; Toxicology; Mode of action; Genetics; Toxicity; Chemistry; Medicine","authors":[{"name":"Jennifer C. Sasaki","is_ca":false},{"name":"Ashley Allemang","is_ca":false},{"name":"Steven M. Bryce","is_ca":false},{"name":"Laura Custer","is_ca":false},{"name":"Kerry L. Dearfield","is_ca":false},{"name":"Yasmin Dietz","is_ca":false},{"name":"Azeddine Elhajouji","is_ca":false},{"name":"Patricia A. Escobar","is_ca":false},{"name":"Albert J. Fornace","is_ca":false},{"name":"Roland Froetschl","is_ca":false},{"name":"Sheila M. Galloway","is_ca":false},{"name":"Ulrike Hemmann","is_ca":false},{"name":"Giel Hendriks","is_ca":false},{"name":"Heng‐Hong Li","is_ca":false},{"name":"Mirjam Luijten","is_ca":false},{"name":"Gladys Ouédraogo","is_ca":false},{"name":"Lauren Peel","is_ca":false},{"name":"Stefan Pfuhler","is_ca":false},{"name":"Daniel J. Roberts","is_ca":false},{"name":"Véronique Thybaud","is_ca":false},{"name":"Jan van Benthem","is_ca":false},{"name":"Carole L. Yauk","is_ca":true},{"name":"Maik Schuler","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005020474749312572,"gpt":0.2148163435817632,"spread":0.2097958688324506,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02805519,0.001653545,0.0009973586,0.005146774,0.002385323,0.00550924,0.003259042,0.004166419,0.00691078],"category_scores_gemma":[0.01585042,0.0006082249,0.002909625,0.001548838,0.009044817,0.005103889,0.006822213,0.005665729,0.001028405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006227356,"about_ca_system_score_gemma":0.009784892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004944825,"about_ca_topic_score_gemma":0.006261506,"domain_scores_codex":[0.9850975,0.007061493,0.0008620044,0.001598322,0.004490876,0.0008898531],"domain_scores_gemma":[0.9821124,0.008566879,0.002396881,0.001617469,0.004609984,0.0006962914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002678572,0.0002248019,0.009780368,0.002385269,0.0001364801,0.004356928,0.002415564,0.01449211,0.01019969,0.8511875,0.007377405,0.09717628],"study_design_scores_gemma":[0.00009576468,0.001183954,0.004585437,0.001738387,0.0002364031,0.005082616,0.002881366,0.006973088,0.01519656,0.6556327,0.3062289,0.0001648617],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.03685852,0.01953572,0.6884011,0.04828378,0.001833434,0.002918554,0.001096671,0.0006858646,0.2003863],"genre_scores_gemma":[0.5583884,0.02780494,0.3630045,0.01577069,0.0009973414,0.002867533,0.0008317632,0.0002229469,0.03011186],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02805519,"threshold_uncertainty_score":0.1483718,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1989802276","doi":"10.1002/em.20688","title":"Simultaneous measurement of benzo[<i>a</i>]pyrene‐induced<i>Pig‐a</i>and<i>lacZ</i>mutations, micronuclei and dna adducts in muta<sup>TM</sup>mouse","year":2011,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; Health Canada","keywords":"Molecular biology; Benzo(a)pyrene; Mutant; Biology; Micronucleus test; Mutation frequency; Mutation; Gene mutation; Micronucleus; DNA adduct; DNA; Gene; Carcinogen; Chemistry; Genetics; Toxicity","authors":[{"name":"Christine Lemieux","is_ca":true},{"name":"George R. Douglas","is_ca":true},{"name":"John D. Gingerich","is_ca":true},{"name":"Souk Phonethepswath","is_ca":false},{"name":"Dorothea K. Torous","is_ca":false},{"name":"Stephen D. Dertinger","is_ca":false},{"name":"David H. Phillips","is_ca":false},{"name":"Volker M. Arlt","is_ca":false},{"name":"Paul A. White","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01034063335184007,"gpt":0.1934636000515836,"spread":0.1831229666997435,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003629854,0.0005349559,0.0003548451,0.0005509172,0.0001707249,0.0002928933,0.0002466151,0.0005399774,0.0006771681],"category_scores_gemma":[0.0003111974,0.0002670509,0.0002738485,0.0002754616,0.0002611774,0.0002373948,0.0002333712,0.0005991551,0.0003442958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002156361,"about_ca_system_score_gemma":0.000167109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004952543,"about_ca_topic_score_gemma":0.00102691,"domain_scores_codex":[0.9995827,0.00006889904,0.0000401555,0.0001521963,0.000110288,0.00004566778],"domain_scores_gemma":[0.9993588,0.00007509431,0.0002405049,0.0000743922,0.0001682706,0.00008290476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003867922,0.00000839955,0.0004217815,0.00001066889,0.000004278728,0.000007260461,0.000007372364,0.00001365863,0.9991037,0.000007021394,0.000003600728,0.0003735117],"study_design_scores_gemma":[0.000004258327,0.0004300307,0.0061987,0.000002085072,0.0000219027,0.00009322821,0.00001297621,0.0001641547,0.9927085,0.0000198882,0.0003395693,0.000004803151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771068,0.001330771,0.0195664,0.00004753235,0.00002732864,0.00009910835,0.0005186595,0.0002509991,0.001052359],"genre_scores_gemma":[0.9615915,0.001676427,0.02994401,0.00009948736,0.00001907067,0.0002439416,0.0009825644,0.00008337863,0.005359688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006771681,"threshold_uncertainty_score":0.002265334,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2088782469","doi":"10.1002/em.20668","title":"Hepatic mRNA, microRNA, and miR‐34a‐Target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation","year":2011,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Benzo(a)pyrene; Toxicogenomics; microRNA; Biology; Molecular biology; Carcinogen; DNA damage; Gene expression; Fold change; Gene; DNA microarray; Microarray; Benzopyrene; DNA; Genetics","authors":[{"name":"Amal Malik","is_ca":true},{"name":"Andrew Williams","is_ca":true},{"name":"Christine Lemieux","is_ca":true},{"name":"Paul A. White","is_ca":true},{"name":"Carole L. Yauk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006713481473919868,"gpt":0.1985407865406455,"spread":0.1918273050667256,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001966591,0.0005036293,0.0005369551,0.0008786362,0.0002425275,0.0003692625,0.0002002085,0.0005353708,0.001489929],"category_scores_gemma":[0.0001450758,0.0004783011,0.0005765582,0.0003662861,0.000484871,0.0002859274,0.0002198261,0.001108096,0.0006031851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003677874,"about_ca_system_score_gemma":0.0002075692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007302024,"about_ca_topic_score_gemma":0.001277369,"domain_scores_codex":[0.9996841,0.00002602336,0.00001864373,0.0001125945,0.00008166156,0.00007711378],"domain_scores_gemma":[0.9997261,0.00003362035,0.00009641145,0.00002065608,0.00003788999,0.00008528989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003408996,0.00003547449,0.0002974327,0.00001709028,0.000007168317,0.00002475199,0.00002470895,0.00003181454,0.9986809,0.00001870869,0.00002570324,0.0004954516],"study_design_scores_gemma":[0.00003949282,0.001226858,0.02821951,0.000008782726,0.00005895681,0.0001769088,0.0001052573,0.0008491717,0.9678499,0.0000791595,0.001367396,0.00001855705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917524,0.001378045,0.003032841,0.0001412278,0.0000543846,0.00006204239,0.002158868,0.0002000271,0.001220265],"genre_scores_gemma":[0.9767355,0.001675799,0.005619606,0.0002458406,0.00003235073,0.0004043231,0.003337034,0.0001480947,0.01180145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001489929,"threshold_uncertainty_score":0.004984319,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2122889851","doi":"10.1002/em.21706","title":"Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR‐135b in mouse lung","year":2012,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Carbon black; Carbon Nanoparticles; Nanoparticle; Lung; Carbon fibers; Expression (computer science); Chemistry; Cell biology; Biology; Medicine; Nanotechnology; Internal medicine; Materials science; Computer science; Organic chemistry; Composite material","authors":[{"name":"Julie A. Bourdon","is_ca":true},{"name":"Anne Thoustrup Saber","is_ca":false},{"name":"Sabina Halappanavar","is_ca":true},{"name":"Petra Jackson","is_ca":false},{"name":"Dongmei Wu","is_ca":true},{"name":"Karin Sørig ­Hougaard","is_ca":false},{"name":"Nicklas Raun Jacobsen","is_ca":false},{"name":"Andrew Williams","is_ca":true},{"name":"Ulla Vogel","is_ca":false},{"name":"Håkan Wallin","is_ca":false},{"name":"Carole L. Yauk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004381157799947939,"gpt":0.2087282142600121,"spread":0.2043470564600641,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002031721,0.000402774,0.0002555553,0.000350053,0.0001450509,0.0003345445,0.0001844021,0.0005396897,0.001194925],"category_scores_gemma":[0.0001117676,0.0002756486,0.0004646652,0.0001254972,0.0003824771,0.0002729165,0.0001855533,0.001186117,0.0003931108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002373235,"about_ca_system_score_gemma":0.000209192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007798155,"about_ca_topic_score_gemma":0.001167065,"domain_scores_codex":[0.9996557,0.00002458604,0.00002342349,0.0001092887,0.0001073053,0.00007967874],"domain_scores_gemma":[0.9998063,0.00003350797,0.00005579723,0.00002473009,0.00002252349,0.00005714451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009385269,0.00002388431,0.0001780639,0.00001359021,0.000003049482,0.00003135417,0.00001182272,0.00001655362,0.9991552,0.00002079999,0.00001471824,0.0004370421],"study_design_scores_gemma":[0.000006155485,0.0004334628,0.005396445,0.000003670144,0.00001397473,0.00009379529,0.00002921985,0.000297697,0.9931989,0.00002514795,0.0004973458,0.000004119935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914137,0.001135142,0.004213477,0.000160361,0.00006764942,0.00004704059,0.0007630102,0.0002129889,0.001986724],"genre_scores_gemma":[0.9878951,0.0006758519,0.003627617,0.0001608055,0.0000184406,0.00009982901,0.0008545703,0.00006264191,0.006605025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001194925,"threshold_uncertainty_score":0.003997445,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2132395364","doi":"10.1002/em.1051","title":"Flow cytometric enumeration of micronucleated reticulocytes: High transferability among 14 laboratories","year":2001,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Malaria Research and Control","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; Health Canada; Texas A and M University; Texas Tech University","keywords":"Plasmodium berghei; Micronucleus test; Biology; Reticulocyte; Malaria; Transferability; Enumeration; Immunology; Genetics; Chemistry; Gene; Statistics","authors":[{"name":"Dorothea K. Torous","is_ca":false},{"name":"Nikki E. Hall","is_ca":false},{"name":"Stephen D. Dertinger","is_ca":false},{"name":"Marilyn S. Diehl","is_ca":false},{"name":"Anne H. Illi‐Love","is_ca":false},{"name":"Karin Cederbrant","is_ca":false},{"name":"Kerstin Sandelin","is_ca":false},{"name":"George Bölcsföldi","is_ca":false},{"name":"Lynnette R. Ferguson","is_ca":false},{"name":"Amira Pearson","is_ca":false},{"name":"Jenness B. Majeska","is_ca":false},{"name":"James P. Tarca","is_ca":false},{"name":"Dean R. Hewish","is_ca":false},{"name":"Larissa Doughty","is_ca":false},{"name":"Michael Fenech","is_ca":false},{"name":"James L. Weaver","is_ca":false},{"name":"Dennis D. Broud","is_ca":false},{"name":"D. Gatehouse","is_ca":false},{"name":"Geoffrey M. Hynes","is_ca":false},{"name":"Puntipa Kwanyuen","is_ca":false},{"name":"Jack McLean","is_ca":true},{"name":"James P. McNamee","is_ca":true},{"name":"Monique Parenteau","is_ca":true},{"name":"Veerle Van Hoof","is_ca":false},{"name":"Philippe Vanparys","is_ca":false},{"name":"Marek Lenarczyk","is_ca":false},{"name":"Joanna Siennicka","is_ca":false},{"name":"Bogumila Litwinska","is_ca":false},{"name":"M.G. Slowikowska","is_ca":false},{"name":"P.R. Harbach","is_ca":false},{"name":"Carol W. Johnson","is_ca":false},{"name":"Shuou Zhao","is_ca":false},{"name":"Charles S. Aaron","is_ca":false},{"name":"Anthony M. Lynch","is_ca":false},{"name":"Ian C. Marshall","is_ca":false},{"name":"Brenda E. Rodgers","is_ca":false},{"name":"Carol R. Tometsko","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.00376595765470231,"gpt":0.199099039989395,"spread":0.1953330823346927,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008176031,0.0008407384,0.001280316,0.001957537,0.001014992,0.001412499,0.001649887,0.0008538569,0.002225181],"category_scores_gemma":[0.007427064,0.0004942371,0.0005356304,0.001260708,0.0008971888,0.000676544,0.002286672,0.001019851,0.001327473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006180012,"about_ca_system_score_gemma":0.0008319145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007399942,"about_ca_topic_score_gemma":0.001088414,"domain_scores_codex":[0.9830402,0.003376929,0.001412813,0.005625551,0.005536275,0.001008313],"domain_scores_gemma":[0.9918436,0.002429444,0.001049801,0.002265695,0.002083238,0.0003281668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008019875,0.001120093,0.03767802,0.0001547242,0.0001999666,0.00008161398,0.0007335756,0.001575172,0.8898363,0.0006088333,0.0003838381,0.06682602],"study_design_scores_gemma":[0.0002049755,0.004265043,0.08499833,0.00004310997,0.0003686415,0.0004432888,0.0002133949,0.01183507,0.8888263,0.0007641854,0.007907818,0.0001298246],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.800644,0.0004192794,0.1880718,0.00009902333,0.00005361343,0.002594419,0.00126372,0.001881924,0.004972131],"genre_scores_gemma":[0.781844,0.0003224088,0.207825,0.0001418634,0.00005999123,0.003106679,0.002994912,0.0003737995,0.003331238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008176031,"threshold_uncertainty_score":0.04323947,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2016158172","doi":"10.1002/em.10131","title":"Treatment and sampling protocols for transgenic mutation assays","year":2003,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada; York University","funders":"National Cancer Institute","keywords":"Mutation; Sampling (signal processing); Mutation frequency; Transgene; Biology; Mutant; Mutagenesis; Computational biology; Sampling time; Genetics; Computer science; Statistics; Gene; Mathematics","authors":[{"name":"John A. Heddle","is_ca":true},{"name":"Hans‐Joerg Martus","is_ca":false},{"name":"George R. Douglas","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03449684348144305,"gpt":0.3139318628023363,"spread":0.2794350193208932,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002028931,0.001894698,0.001885422,0.003016019,0.0007524141,0.0007145603,0.002437621,0.001901865,0.006336255],"category_scores_gemma":[0.00171994,0.0007146175,0.0008111881,0.00238613,0.0007533941,0.001130055,0.0008616167,0.002474828,0.01518693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006560889,"about_ca_system_score_gemma":0.000958842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001207024,"about_ca_topic_score_gemma":0.002047936,"domain_scores_codex":[0.9982748,0.0003080917,0.0001959465,0.0002780866,0.0008730125,0.00006997545],"domain_scores_gemma":[0.9990889,0.0001868164,0.0001329955,0.0001772349,0.0003697663,0.00004419241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001961959,0.000235591,0.0005607018,0.009928351,0.00006073369,0.0006955049,0.0001842313,0.0009007427,0.2609113,0.006470752,0.04805011,0.6718058],"study_design_scores_gemma":[0.00001953182,0.0001484411,0.001455054,0.0004706254,0.00005970121,0.002115563,0.00005055781,0.000199782,0.0856445,0.00192183,0.9078486,0.00006575795],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.00619116,0.484421,0.4523282,0.001785445,0.003912965,0.004624541,0.003329551,0.003869204,0.039538],"genre_scores_gemma":[0.01561486,0.6386175,0.2641456,0.002551586,0.001035381,0.007488814,0.007236759,0.0006213867,0.06268805],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.006336255,"threshold_uncertainty_score":0.02119684,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2003176615","doi":"10.1002/em.10115","title":"Genotoxicity biomonitoring in regions exposed to vehicle emissions using the comet assay and the micronucleus test in native rodent <i>Ctenomys minutus</i>","year":2002,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"University of Guelph","keywords":"Genotoxicity; Comet assay; Micronucleus test; Rodent; Micronucleus; Biology; Biomonitoring; Toxicology; Population; Ecotoxicology; DNA damage; Environmental chemistry; Ecology; Toxicity; Chemistry; Genetics; DNA; Medicine; Environmental health","authors":[{"name":"Vanina D. Heuser","is_ca":false},{"name":"Juliana da Silva","is_ca":false},{"name":"Heinz‐Jörn Moriske","is_ca":false},{"name":"Johnny Ferraz Dias","is_ca":false},{"name":"M.‐L. Yoneama","is_ca":false},{"name":"Thales Renato Ochotorena de Freitas","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01254575961186178,"gpt":0.2245815975616455,"spread":0.2120358379497837,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001966353,0.0003578792,0.0002169522,0.000719098,0.000266959,0.0002284668,0.0001538002,0.0002706097,0.0003869496],"category_scores_gemma":[0.0001986788,0.0001603001,0.0002087123,0.0002396508,0.0002763544,0.000161825,0.0002205933,0.0001316869,0.00008495982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001972518,"about_ca_system_score_gemma":0.0001600497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003401185,"about_ca_topic_score_gemma":0.008195945,"domain_scores_codex":[0.9998704,0.00002016805,0.00001277463,0.00004613265,0.00003344001,0.00001699399],"domain_scores_gemma":[0.9998586,0.000009678763,0.00007429296,0.000009148563,0.00002833853,0.00001986885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002819395,0.00009075345,0.2502911,0.0001154935,0.00005127135,0.0002773238,0.0003748097,0.0001851339,0.7419426,0.00005819548,0.00002727898,0.006303971],"study_design_scores_gemma":[0.00001292357,0.002010775,0.8978971,0.00001922177,0.00007084885,0.001088039,0.0004333872,0.0003237372,0.09739725,0.00004235439,0.0006940755,0.00001028331],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991741,0.0002113041,0.000292791,0.000005233345,0.000001523106,0.00001543679,0.00006685017,0.000004155374,0.0002286994],"genre_scores_gemma":[0.9976327,0.0002518515,0.001327911,0.00001759746,0.000002987911,0.00002843805,0.0002771056,0.000002354702,0.0004588941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003401185,"threshold_uncertainty_score":0.006762803,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2116445432","doi":"10.1002/em.20369","title":"Recent developments in frameworks to consider human relevance of hypothesized modes of action for tumours in animals","year":2008,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Population and Public Health; University of Ottawa","funders":"","keywords":"Relevance (law); Action (physics); Hazard; Human health; Risk analysis (engineering); Engineering ethics; Political science; Biology; Medicine; Environmental health; Engineering","authors":[{"name":"M.E. Meek","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03975656061684087,"gpt":0.3298106279205939,"spread":0.290054067303753,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009448345,0.001281762,0.002006784,0.004017783,0.0007872581,0.002808558,0.00213266,0.002834897,0.003142329],"category_scores_gemma":[0.006152056,0.0005046408,0.0008265789,0.003023735,0.00684855,0.003849662,0.002539331,0.005392496,0.001165815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003185198,"about_ca_system_score_gemma":0.003930606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002861021,"about_ca_topic_score_gemma":0.003616489,"domain_scores_codex":[0.9971877,0.001256627,0.0002389926,0.0003055033,0.0009316166,0.00007958418],"domain_scores_gemma":[0.9921348,0.006075623,0.0005070057,0.0002517766,0.0008842015,0.0001465995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005502278,0.00006802128,0.000307866,0.0155158,0.0001124434,0.0004695367,0.001370689,0.002196283,0.001535242,0.2830563,0.01952956,0.6757832],"study_design_scores_gemma":[0.00000885261,0.0000557483,0.0004688968,0.004441553,0.00005646895,0.0008735175,0.0004389569,0.0001968148,0.000405025,0.0762755,0.9167392,0.00003938512],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002855338,0.9800906,0.004984394,0.005212588,0.0007713847,0.0000207991,0.00001824053,0.00002122088,0.008595318],"genre_scores_gemma":[0.005566155,0.9807447,0.008123178,0.002564391,0.0009766391,0.00005161205,0.00003725633,0.00001259596,0.001923608],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009448345,"threshold_uncertainty_score":0.04996824,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1537938460","doi":"10.1002/em.21940","title":"Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human <scp>TK</scp>6 cells","year":2015,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"National Cancer Institute; National Institute of Environmental Health Sciences; Health Canada","keywords":"Toxicogenomics; Genotoxicity; Biomarker; Transcriptome; Micronucleus test; DNA microarray; Computational biology; Carcinogen; Biology; Toxicology; Chemistry; Genetics; Gene; Gene expression; Toxicity","authors":[{"name":"Julie K. Buick","is_ca":true},{"name":"Ivy D. Moffat","is_ca":true},{"name":"Andrew Williams","is_ca":true},{"name":"Carol D. Swartz","is_ca":false},{"name":"Leslie Recio","is_ca":false},{"name":"Daniel R. Hyduke","is_ca":false},{"name":"Heng‐Hong Li","is_ca":false},{"name":"Albert J. Fornace","is_ca":false},{"name":"Jiri Aubrecht","is_ca":false},{"name":"Carole L. Yauk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01131390365599133,"gpt":0.2305628651853638,"spread":0.2192489615293724,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003750766,0.0004426453,0.0004058161,0.0006753584,0.0001421929,0.0005456827,0.0001691215,0.0004125361,0.0008214156],"category_scores_gemma":[0.000478269,0.000168518,0.0004070346,0.0006694797,0.0001573432,0.0001925116,0.0002047598,0.0003625158,0.0003246565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003889804,"about_ca_system_score_gemma":0.000337276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001648445,"about_ca_topic_score_gemma":0.003397453,"domain_scores_codex":[0.9997454,0.00003013137,0.00002560848,0.0000741604,0.0001015871,0.00002306884],"domain_scores_gemma":[0.9996521,0.00007424334,0.00009709419,0.00003158398,0.0001163648,0.0000285777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003021542,0.00004156449,0.01111574,0.00006412193,0.00002818392,0.0000566575,0.00002571045,0.001293711,0.9766749,0.00006393794,0.0001121702,0.01022118],"study_design_scores_gemma":[0.00001262772,0.0006267536,0.05312535,0.00000903319,0.00008358331,0.0003531553,0.00009317601,0.01815704,0.9253049,0.0001867512,0.002014978,0.00003263171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9545695,0.0008942673,0.03673793,0.0002732041,0.00004004572,0.0001148246,0.005508186,0.0004849781,0.001377034],"genre_scores_gemma":[0.9463632,0.0008151117,0.04395098,0.0001632341,0.00001232706,0.0001322029,0.006288045,0.0000575235,0.002217372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001648445,"threshold_uncertainty_score":0.003277659,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2591577933","doi":"10.1002/em.22079","title":"Main issues addressed in the 2014–2015 revisions to the OECD Genetic Toxicology Test Guidelines","year":2017,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Consistency (knowledge bases); Reliability (semiconductor); Toxicology; Computer science; Test (biology); Reliability engineering; Process (computing); Risk analysis (engineering); Biology; Medicine; Engineering; Power (physics); Artificial intelligence","authors":[{"name":"Véronique Thybaud","is_ca":false},{"name":"Elisabeth Lorge","is_ca":false},{"name":"Dan D. Levy","is_ca":false},{"name":"Jan van Benthem","is_ca":false},{"name":"George R. Douglas","is_ca":true},{"name":"Francesco Marchetti","is_ca":true},{"name":"Martha M. Moore","is_ca":false},{"name":"Rita Schoeny","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01599653929197601,"gpt":0.3075337702783973,"spread":0.2915372309864213,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.08392303,0.001481719,0.00102549,0.005228862,0.002378368,0.005632067,0.006194687,0.006626762,0.00197411],"category_scores_gemma":[0.1371338,0.00100437,0.002833029,0.003803133,0.004078588,0.002939355,0.003677448,0.008995412,0.001741478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009000617,"about_ca_system_score_gemma":0.02737866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04600102,"about_ca_topic_score_gemma":0.03467064,"domain_scores_codex":[0.8727354,0.03469201,0.01870514,0.005277469,0.06378812,0.004801844],"domain_scores_gemma":[0.8528666,0.0292415,0.01184241,0.006992557,0.09702729,0.002029707],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005451558,0.0004360678,0.01742617,0.003526058,0.0002916631,0.002101006,0.004811697,0.007180666,0.0185826,0.1079835,0.4926574,0.344458],"study_design_scores_gemma":[0.00005172113,0.0003125397,0.01029179,0.003076639,0.0002507333,0.0007834098,0.001565202,0.001019015,0.01274875,0.01346588,0.9561908,0.0002436875],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.06278405,0.05716628,0.1957121,0.4255736,0.05745807,0.005094004,0.0163404,0.003654633,0.176217],"genre_scores_gemma":[0.262794,0.0462384,0.3098254,0.2580163,0.006417751,0.005391292,0.01943913,0.001633834,0.0902439],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.916077,"threshold_uncertainty_score":0.4438327,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2059745128","doi":"10.1002/em.20359","title":"Tandem repeat mutation, global DNA methylation, and regulation of DNA methyltransferases in cultured mouse embryonic fibroblast cells chronically exposed to chemicals with different modes of action","year":2008,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Lethbridge; Health Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"DNA methylation; DNMT3B; Methyltransferase; Methylation; DNA methyltransferase; DNMT1; Molecular biology; Epigenetics; Biology; Mutation; DNA; DNA repair; Genetics; Chemistry; Gene expression; Gene","authors":[{"name":"Carole L. Yauk","is_ca":true},{"name":"Aris Polyzos","is_ca":false},{"name":"Andrea Rowan‐Carroll","is_ca":true},{"name":"Igor Kortubash","is_ca":true},{"name":"Andrew Williams","is_ca":true},{"name":"Olga Kovalchuk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008219655928987683,"gpt":0.2161246008616285,"spread":0.2079049449326409,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822088,0.000371656,0.0002143183,0.000299957,0.0001420767,0.0001586361,0.0001904199,0.0002800064,0.0007615827],"category_scores_gemma":[0.0001215071,0.000183952,0.0003063102,0.0001967311,0.0002129056,0.0001216418,0.0001380767,0.0003761582,0.0002164611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002567686,"about_ca_system_score_gemma":0.0001630471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0016264,"about_ca_topic_score_gemma":0.002916639,"domain_scores_codex":[0.9997854,0.00003653954,0.00002605435,0.00006329117,0.00006101605,0.00002771314],"domain_scores_gemma":[0.999841,0.00003813077,0.0000428616,0.0000251827,0.00002837673,0.00002446762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002294938,0.000003636095,0.0002215609,0.000005356889,0.000001973181,0.00001342712,0.000006225192,0.00001109967,0.9995136,0.000006563542,0.000002290767,0.0001912347],"study_design_scores_gemma":[0.000002727292,0.0001985536,0.007980422,0.000001375427,0.000008637609,0.0000953858,0.00001313556,0.0001846429,0.9912599,0.00001039378,0.0002426368,0.000002294521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939342,0.001368428,0.003172329,0.00002679038,0.00001312718,0.00002736002,0.0005797773,0.00003616,0.0008417962],"genre_scores_gemma":[0.9915112,0.0009180692,0.003536933,0.00002747456,0.000006170229,0.00008970447,0.001000686,0.00001498192,0.002894913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0016264,"threshold_uncertainty_score":0.00323379,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4220819700","doi":"10.1002/em.22479","title":"<scp>AOP</scp> report: Development of an adverse outcome pathway for oxidative <scp>DNA</scp> damage leading to mutations and chromosomal aberrations","year":2022,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Carleton University; University of Ottawa; Health Canada","funders":"Health Canada; Natural Sciences and Engineering Research Council of Canada; Health and Environmental Sciences Institute","keywords":"Genotoxicity; DNA damage; Adverse Outcome Pathway; DNA repair; Biology; Base excision repair; Computational biology; Genetics; DNA; Chemistry; Toxicity","authors":[{"name":"Eunnara Cho","is_ca":true},{"name":"Ashley Allemang","is_ca":false},{"name":"Marc Audebert","is_ca":false},{"name":"Vinita Chauhan","is_ca":true},{"name":"Stephen D. Dertinger","is_ca":false},{"name":"Giel Hendriks","is_ca":false},{"name":"Mirjam Luijten","is_ca":false},{"name":"Francesco Marchetti","is_ca":true},{"name":"Sheroy Minocherhomji","is_ca":false},{"name":"Stefan Pfuhler","is_ca":false},{"name":"Daniel J. Roberts","is_ca":false},{"name":"Kristina Trenz","is_ca":false},{"name":"Carole L. Yauk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01122451912566868,"gpt":0.2494714012561772,"spread":0.2382468821305085,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007384599,0.001393025,0.0006350251,0.003703753,0.001651743,0.002689742,0.002711002,0.004305381,0.0422994],"category_scores_gemma":[0.01340806,0.0004865248,0.00127223,0.001751294,0.001260056,0.00189944,0.0023264,0.002897772,0.01766567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002943994,"about_ca_system_score_gemma":0.007721028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01095262,"about_ca_topic_score_gemma":0.01463646,"domain_scores_codex":[0.9937245,0.001064435,0.0004203228,0.0004267441,0.003982238,0.00038177],"domain_scores_gemma":[0.9790872,0.00389135,0.002630082,0.001583082,0.01091848,0.001889829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004014912,0.0004174119,0.004214425,0.001403452,0.00009690649,0.001337415,0.0001365209,0.003276335,0.01364214,0.0104924,0.9072271,0.05735459],"study_design_scores_gemma":[0.0001379288,0.0009768944,0.007029479,0.0005057692,0.000100511,0.0007773707,0.0001450146,0.003523889,0.04112965,0.009731294,0.935834,0.0001082652],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"other","genre_gemma":"methods","genre_scores_codex":[0.03443205,0.01197016,0.120796,0.1606436,0.04010868,0.01344516,0.1230353,0.01186643,0.4837028],"genre_scores_gemma":[0.1692388,0.02939168,0.1159568,0.05621716,0.0201475,0.006608685,0.1431175,0.004017674,0.4553043],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.0422994,"threshold_uncertainty_score":0.1415055,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2254077104","doi":"10.1002/em.21994","title":"Exposure to persistent organic pollutants and sperm <scp>DNA</scp> methylation changes in Arctic and European populations","year":2016,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"DNA methylation; Pollutant; Sperm; Methylation; DNA; Biology; Arctic; Genetics; The arctic; Ecology; Gene; Gene expression","authors":[{"name":"Claudia Consales","is_ca":false},{"name":"Gunnar Toft","is_ca":false},{"name":"Giorgio Leter","is_ca":false},{"name":"Jens Peter Bonde","is_ca":false},{"name":"Raffaella Uccelli","is_ca":false},{"name":"Francesca Pacchierotti","is_ca":false},{"name":"Patrizia Eleuteri","is_ca":false},{"name":"Bo Jönsson","is_ca":false},{"name":"Aleksander Giwercman","is_ca":false},{"name":"Henning Sloth Pedersen","is_ca":false},{"name":"Paweł Struciński","is_ca":false},{"name":"Katarzyna Góralczyk","is_ca":false},{"name":"Valentyna Zviezdai","is_ca":false},{"name":"Marcello Spanò","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009503474287416188,"gpt":0.2066825283723257,"spread":0.1971790540849095,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002295235,0.0001279187,0.0001384413,0.0003763822,0.0002246698,0.0002765099,0.0001024003,0.0001817271,0.00056691],"category_scores_gemma":[0.0003511586,0.0001113051,0.0001441453,0.0004289169,0.0001377006,0.00008426841,0.0001803825,0.0001218525,0.00008028329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002080969,"about_ca_system_score_gemma":0.0001736642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02271906,"about_ca_topic_score_gemma":0.01835385,"domain_scores_codex":[0.9998666,0.00003119863,0.00001023781,0.00005241931,0.00001954307,0.00001999073],"domain_scores_gemma":[0.9998666,0.00001996478,0.00004778389,0.00001074764,0.00002770382,0.00002723314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002224381,0.00002358006,0.9901861,0.00000999462,0.0001137122,0.00006435972,0.0002667415,0.0001022559,0.005372134,0.00003121225,0.00004413363,0.003563381],"study_design_scores_gemma":[0.000001010609,0.00003924807,0.999301,0.000001907522,0.00001745515,0.00007182868,0.0001376806,0.00007447229,0.0002350265,0.000009684294,0.0001095039,0.000001210798],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996238,0.0001188529,0.00004834343,0.000005531969,8.422427e-7,5.881221e-7,0.0000829495,9.988124e-7,0.0001180926],"genre_scores_gemma":[0.9994577,0.000099886,0.00006759224,0.000008083219,0.000001692981,0.00000178013,0.000135721,9.93675e-7,0.0002267844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02271906,"threshold_uncertainty_score":0.04517365,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2013892932","doi":"10.1002/em.1073","title":"ERCC1: A comparative genomic perspective","year":2001,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Victoria","funders":"Joint Genome Institute","keywords":"Biology; Genetics; ERCC1; genomic DNA; Exon; Gene; Nucleotide excision repair; DNA repair","authors":[{"name":"Michael D. Wilson","is_ca":true},{"name":"Cindy C. Ruttan","is_ca":true},{"name":"Ben F. Koop","is_ca":true},{"name":"Barry W. Glickman","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007339981184908122,"gpt":0.2217347981068716,"spread":0.2143948169219634,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002730385,0.0005376104,0.0005758404,0.002269125,0.0003994305,0.0008851325,0.000595381,0.0007229769,0.004829486],"category_scores_gemma":[0.0002123937,0.0001480487,0.0003187754,0.002714349,0.0002594826,0.0008297671,0.0003264968,0.000711722,0.00216943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006661561,"about_ca_system_score_gemma":0.0002678858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001428809,"about_ca_topic_score_gemma":0.001516658,"domain_scores_codex":[0.9998291,0.00002412185,0.000008022561,0.00007915946,0.00003807704,0.00002158896],"domain_scores_gemma":[0.9998819,0.00002463197,0.00002047737,0.00001401978,0.00003360856,0.00002530866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006848797,0.00005113231,0.001347553,0.00162862,0.00009439886,0.001266842,0.0001447766,0.0006857464,0.8662553,0.008680758,0.00844791,0.1107121],"study_design_scores_gemma":[0.00004829216,0.0004399936,0.03659814,0.0003030631,0.0001931506,0.009039436,0.0002954515,0.002245878,0.1547744,0.005411698,0.7905793,0.00007123499],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2201463,0.5453923,0.08245988,0.005815405,0.001884028,0.0002372329,0.03152534,0.002315621,0.110224],"genre_scores_gemma":[0.5572425,0.2268514,0.1201141,0.001913036,0.001810907,0.0002153723,0.05919318,0.0004166235,0.03224283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004829486,"threshold_uncertainty_score":0.01615626,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2756586263","doi":"10.1002/em.22137","title":"Comparing BMD‐derived genotoxic potency estimations across variants of the transgenic rodent gene mutation assay","year":2017,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"University of Ottawa; Health Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Chugoku Marine Paints; Government of Canada; Gilead Sciences","keywords":"Ethyl methanesulfonate; Biology; Potency; Transgene; Toxicogenomics; In vivo; Genetics; Toxicology; Point mutation; Confidence interval; In silico; Computational biology; Pharmacology; Mutation; Gene; Gene expression; Internal medicine; Medicine; In vitro","authors":[{"name":"John W. Wills","is_ca":true},{"name":"George E. Johnson","is_ca":false},{"name":"Hannah L. Battaion","is_ca":true},{"name":"Wout Slob","is_ca":false},{"name":"Paul A. White","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01148689671970721,"gpt":0.2490401464580598,"spread":0.2375532497383526,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007947756,0.001090344,0.001128957,0.003819749,0.000331933,0.001161447,0.001282479,0.0009261775,0.001448254],"category_scores_gemma":[0.009620159,0.0004278724,0.001576873,0.002971,0.0006859361,0.0008889067,0.001161032,0.001198822,0.000740367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008962397,"about_ca_system_score_gemma":0.000858714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001478194,"about_ca_topic_score_gemma":0.003107748,"domain_scores_codex":[0.9921057,0.001949143,0.0009165965,0.00128939,0.003549641,0.0001895357],"domain_scores_gemma":[0.9889187,0.00428254,0.002043508,0.001648558,0.002965177,0.0001415466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00093447,0.0002457507,0.0504053,0.0047568,0.001466575,0.0003370579,0.0003618742,0.01305592,0.8335835,0.001530862,0.001726748,0.09159508],"study_design_scores_gemma":[0.00004846125,0.004760688,0.1056422,0.0005004435,0.002594232,0.001758785,0.000498942,0.009089216,0.8339279,0.003469265,0.03748918,0.0002206422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6392463,0.04345877,0.2780103,0.000522556,0.0002725904,0.001083438,0.02178294,0.001527571,0.01409551],"genre_scores_gemma":[0.8464314,0.02547793,0.09292872,0.0007026982,0.00005614783,0.001146817,0.02795674,0.0005146313,0.004784889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007947756,"threshold_uncertainty_score":0.04203224,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049474570","doi":"10.1002/em.20613","title":"Germ cell mutagens: Risk assessment challenges in the 21st century","year":2010,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"De La Salle University; U.S. Environmental Protection Agency","keywords":"Germline; Germline mutation; Biology; Mutation; Genetics; Mutagen; Computational biology; Somatic cell; Risk analysis (engineering); Biotechnology; Business; Carcinogen; Gene","authors":[{"name":"Timothy M. Singer","is_ca":true},{"name":"Carole L. Yauk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01121679175909194,"gpt":0.2816881795630943,"spread":0.2704713878040023,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002266692,0.001633432,0.00220059,0.002092285,0.0005405178,0.001992688,0.002001066,0.004970254,0.00384445],"category_scores_gemma":[0.002180432,0.0003959338,0.0005647213,0.002343371,0.002373886,0.003919812,0.001306007,0.003880346,0.002865687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001783997,"about_ca_system_score_gemma":0.002280315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002325323,"about_ca_topic_score_gemma":0.003310027,"domain_scores_codex":[0.9993338,0.0001509565,0.000061858,0.0001079849,0.000308242,0.00003718362],"domain_scores_gemma":[0.9977195,0.001319955,0.0001636053,0.00008883865,0.0005660222,0.0001419742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003734194,0.00006465388,0.0001930241,0.005674629,0.00004738821,0.0003052666,0.0001092157,0.0009598946,0.001518952,0.01417837,0.03949839,0.9374129],"study_design_scores_gemma":[0.000009858909,0.0000769075,0.0004688436,0.002537783,0.00004111214,0.00152666,0.000186153,0.0002117605,0.0005606404,0.0148569,0.9794899,0.00003361869],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001146824,0.9940016,0.0009734699,0.002519051,0.0004672564,0.000004372718,0.00001091669,0.00002182278,0.001886846],"genre_scores_gemma":[0.0009804035,0.9945344,0.001139999,0.001166945,0.0004838904,0.000008519232,0.00001954499,0.000006170008,0.001660159],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004970254,"threshold_uncertainty_score":0.01294386,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2903288588","doi":"10.1002/em.22257","title":"Assessment of the performance of the TGx‐DDI biomarker to detect DNA damage‐inducing agents using quantitative RT‐PCR in TK6 cells","year":2018,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Carleton University; Health Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Health Canada; U.S. Environmental Protection Agency","keywords":"Biomarker; DNA damage; DNA; Real-time polymerase chain reaction; Biology; Computational biology; Gene; Genetics","authors":[{"name":"Eunnara Cho","is_ca":true},{"name":"Julie K. Buick","is_ca":true},{"name":"Andrew Williams","is_ca":true},{"name":"Renxiang Chen","is_ca":false},{"name":"Heng‐Hong Li","is_ca":false},{"name":"J. Christopher Corton","is_ca":false},{"name":"Albert J. Fornace","is_ca":false},{"name":"Jiri Aubrecht","is_ca":false},{"name":"Carole L. Yauk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01268925280343336,"gpt":0.2775545090567434,"spread":0.2648652562533101,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002634028,0.001133246,0.0007156436,0.0006907482,0.0003426399,0.0009753244,0.0005429452,0.0008164155,0.0007690404],"category_scores_gemma":[0.002319349,0.0003852347,0.0007417943,0.0006077967,0.0005745761,0.0004797509,0.0004181793,0.0009089703,0.0007387956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005099584,"about_ca_system_score_gemma":0.000495255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00145676,"about_ca_topic_score_gemma":0.002112769,"domain_scores_codex":[0.9975432,0.0004253905,0.000302537,0.000707838,0.0008275749,0.0001934915],"domain_scores_gemma":[0.9981928,0.0006316393,0.0003063498,0.0002094051,0.0005930958,0.00006668059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005366194,0.00003074187,0.0007866115,0.00004145511,0.00001043149,0.000008148116,0.00004164174,0.0004572851,0.9964749,0.00003343647,0.00002532986,0.002036202],"study_design_scores_gemma":[0.000004349168,0.000226167,0.003154,0.000004862001,0.00002222471,0.00003795545,0.00003160353,0.005312053,0.990586,0.00003858259,0.0005703073,0.00001196013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8324032,0.00231986,0.1590801,0.0003096231,0.0001768571,0.0004084955,0.002660996,0.0005982983,0.002042578],"genre_scores_gemma":[0.7950145,0.001986524,0.1907779,0.0003125199,0.00004919691,0.001238631,0.00354858,0.0001886403,0.00688357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002634028,"threshold_uncertainty_score":0.01393026,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2033785453","doi":"10.1002/em.20081","title":"Interlaboratory validation of a CD71-based flow cytometric method (Microflow®) for the scoring of micronucleated reticulocytes in mouse peripheral blood","year":2004,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Immunotoxicology and immune responses","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; Johnson and Johnson","keywords":"Peripheral blood; Peripheral; Flow cytometry; Micronucleus test; Biology; Toxicology; Chromatography; Medicine; Molecular biology; Chemistry; Immunology; Internal medicine; Toxicity","authors":[{"name":"Dorothea K. Torous","is_ca":false},{"name":"Nikki E. Hall","is_ca":false},{"name":"Anne H. Illi‐Love","is_ca":false},{"name":"Marilyn S. Diehl","is_ca":false},{"name":"Karin Cederbrant","is_ca":false},{"name":"Kerstin Sandelin","is_ca":false},{"name":"Ingrid Pontén","is_ca":false},{"name":"George Bölcsföldi","is_ca":false},{"name":"Lynnette R. Ferguson","is_ca":false},{"name":"Amira Pearson","is_ca":false},{"name":"Jenness B. Majeska","is_ca":false},{"name":"James P. Tarca","is_ca":false},{"name":"Geoffrey M. Hynes","is_ca":false},{"name":"Anthony M. Lynch","is_ca":false},{"name":"James P. McNamee","is_ca":true},{"name":"Pascale V. Bellier","is_ca":true},{"name":"Monique Parenteau","is_ca":true},{"name":"David H. Blakey","is_ca":true},{"name":"Janet Bayley","is_ca":true},{"name":"Bas‐jan M. van der Leede","is_ca":false},{"name":"Philippe Vanparys","is_ca":false},{"name":"P.R. Harbach","is_ca":false},{"name":"Shuou Zhao","is_ca":false},{"name":"A.L. Filipunas","is_ca":false},{"name":"Carol W. Johnson","is_ca":false},{"name":"Carol R. Tometsko","is_ca":false},{"name":"Stephen D. Dertinger","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005618362547706507,"gpt":0.220422473306948,"spread":0.2148041107592415,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03094583,0.001804264,0.0008366873,0.002130489,0.001665956,0.001420948,0.001755146,0.001981287,0.002176368],"category_scores_gemma":[0.01777126,0.0008609778,0.001019793,0.001300347,0.001345276,0.0005326424,0.001879724,0.001297896,0.001750255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001155427,"about_ca_system_score_gemma":0.001810122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001924576,"about_ca_topic_score_gemma":0.003477837,"domain_scores_codex":[0.952989,0.01993724,0.004613146,0.009899949,0.01150773,0.001052819],"domain_scores_gemma":[0.9726185,0.00623588,0.003220051,0.007824172,0.009525999,0.0005753326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00111218,0.0006935694,0.02277567,0.0002886314,0.0002218095,0.00008856138,0.0009464361,0.001166701,0.9515715,0.0006878984,0.0007968601,0.01965029],"study_design_scores_gemma":[0.0002461784,0.00570844,0.06246865,0.0001527627,0.000436102,0.0007209551,0.0002237764,0.006905981,0.9100644,0.0003873304,0.01259005,0.0000953338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5328881,0.001364744,0.4461008,0.0003738076,0.0005320955,0.005862002,0.002980317,0.001999269,0.007898876],"genre_scores_gemma":[0.6477261,0.0005137628,0.323404,0.0008133603,0.0001456096,0.011567,0.007199582,0.0006110121,0.008019575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03094583,"threshold_uncertainty_score":0.1636592,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2896113647","doi":"10.1002/em.22243","title":"Using a gene expression biomarker to identify DNA damage‐inducing agents in microarray profiles","year":2018,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"U.S. Environmental Protection Agency","keywords":"Biomarker; Toxicogenomics; Biology; False positive paradox; Computational biology; Gene; Context (archaeology); Microarray; DNA damage; Transcriptome; DNA microarray; Gene expression; Genetics; DNA; Computer science; Machine learning","authors":[{"name":"J. Christopher Corton","is_ca":false},{"name":"Andrew Williams","is_ca":true},{"name":"Carole L. Yauk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02280551860648428,"gpt":0.3092974983974899,"spread":0.2864919797910057,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001464534,0.0007335271,0.0005697107,0.001360762,0.0003086307,0.0008029504,0.000337032,0.0007438748,0.0008685117],"category_scores_gemma":[0.002879677,0.0002565616,0.0005115116,0.001246205,0.0003859297,0.0006097476,0.000383721,0.00066784,0.0005640438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005164635,"about_ca_system_score_gemma":0.0004061863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008067813,"about_ca_topic_score_gemma":0.00187509,"domain_scores_codex":[0.9987436,0.0002730958,0.0001020941,0.0003952027,0.0003856586,0.0001004021],"domain_scores_gemma":[0.9985923,0.0006907612,0.0002686717,0.0001277038,0.0002719855,0.00004854443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002033312,0.00008061573,0.02515126,0.0001873957,0.00006957242,0.00006668903,0.0001056195,0.003496845,0.9459208,0.0004306823,0.0002929466,0.02399423],"study_design_scores_gemma":[0.00001582242,0.0005343524,0.09408075,0.00003199651,0.00011742,0.0003269959,0.0001786812,0.05295953,0.8464955,0.001260058,0.00393632,0.00006250159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.6945698,0.001568971,0.2925127,0.0006033935,0.0001515899,0.0003111251,0.004598827,0.001590215,0.004093356],"genre_scores_gemma":[0.7907593,0.0009214891,0.2019033,0.0004545731,0.00004628505,0.0005056941,0.002876062,0.00008925439,0.002444064],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001464534,"threshold_uncertainty_score":0.007745266,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2291048411","doi":"10.1002/em.22004","title":"Application of the TGx‐28.65 transcriptomic biomarker to classify genotoxic and non‐genotoxic chemicals in human TK6 cells in the presence of rat liver S9","year":2016,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"National Institute of Environmental Health Sciences; Health Canada","keywords":"Genotoxicity; Micronucleus; Transcriptome; Biomarker; Toxicogenomics; Biology; Micronucleus test; Carcinogen; DNA damage; Flow cytometry; Toxicity; Molecular biology; Chemistry; Gene; Genetics; Gene expression; DNA","authors":[{"name":"Carole L. Yauk","is_ca":true},{"name":"Julie K. Buick","is_ca":true},{"name":"Andrew Williams","is_ca":true},{"name":"Carol D. Swartz","is_ca":false},{"name":"Leslie Recio","is_ca":false},{"name":"Heng‐Hong Li","is_ca":false},{"name":"Albert J. Fornace","is_ca":false},{"name":"Errol M. Thomson","is_ca":true},{"name":"Jiri Aubrecht","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005215428374721841,"gpt":0.2117433215012595,"spread":0.2065278931265376,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000164885,0.0003080422,0.0002639121,0.0003216425,0.0001215676,0.0002642371,0.00008600081,0.0002749869,0.0009164027],"category_scores_gemma":[0.0002339033,0.00013593,0.0003330501,0.0003169121,0.0001212676,0.0001025356,0.0001623051,0.0002088982,0.0003839076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001980403,"about_ca_system_score_gemma":0.0002000701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001087369,"about_ca_topic_score_gemma":0.002134308,"domain_scores_codex":[0.9998505,0.00001760431,0.00001340918,0.0000491272,0.00005207874,0.00001722929],"domain_scores_gemma":[0.9998909,0.00001741355,0.00003118083,0.00001030729,0.00003656693,0.00001351719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000860412,0.000009053528,0.002283196,0.00002096896,0.000005059102,0.00001549107,0.00001668835,0.0001090582,0.9963685,0.00001006591,0.00001490091,0.001060888],"study_design_scores_gemma":[0.000009321707,0.000656915,0.03844481,0.000008434175,0.00003778429,0.0002044201,0.0001111601,0.001775849,0.9574038,0.00004192954,0.001297766,0.000007764378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892067,0.0006188528,0.006200364,0.00007565264,0.00001272832,0.0000657723,0.003153887,0.00006871954,0.0005973461],"genre_scores_gemma":[0.9784194,0.0006921447,0.01184101,0.00009888919,0.000005978975,0.0001074507,0.006269065,0.00001866792,0.002547413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001087369,"threshold_uncertainty_score":0.003065646,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1937139133","doi":"10.1002/em.21954","title":"Development of the adverse outcome pathway “alkylation of <scp>DNA</scp> in male premeiotic germ cells leading to heritable mutations” using the <scp>OECD</scp>'s users' handbook supplement","year":2015,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Genetically Modified Organisms Research","field":"Agricultural and Biological Sciences","cited_by":38,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Population and Public Health; Carleton University; University of Ottawa; Health Canada","funders":"","keywords":"Adverse Outcome Pathway; Germ cell; DNA repair; Biology; DNA damage; Mutagen; Genetics; DNA; Computational biology; Gene","authors":[{"name":"Carole L. Yauk","is_ca":true},{"name":"Iain B. Lambert","is_ca":true},{"name":"M.E. Meek","is_ca":true},{"name":"George R. Douglas","is_ca":true},{"name":"Francesco Marchetti","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.032401135062696,"gpt":0.2332018185668149,"spread":0.2008006835041188,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009245094,0.001267093,0.001086966,0.004269694,0.0008370645,0.00272651,0.002593828,0.002075755,0.04197362],"category_scores_gemma":[0.0108837,0.0009820402,0.001403142,0.002220188,0.000668287,0.002249992,0.003313739,0.001785149,0.03230007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001865451,"about_ca_system_score_gemma":0.008972852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00916643,"about_ca_topic_score_gemma":0.01205124,"domain_scores_codex":[0.993505,0.00141322,0.0006103295,0.0004248616,0.003792381,0.0002541537],"domain_scores_gemma":[0.9887799,0.002200691,0.0008011457,0.001658043,0.006137518,0.0004226719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003393649,0.0003166042,0.001881452,0.007941621,0.00008549947,0.0005956938,0.0006068313,0.003539406,0.02631805,0.01588961,0.4739442,0.4685417],"study_design_scores_gemma":[0.00002433094,0.0001692489,0.0008949042,0.0007374196,0.00003756816,0.0001792846,0.00007053266,0.0004875887,0.01391298,0.001735194,0.9817178,0.00003305743],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.01625724,0.0193682,0.3560731,0.0169667,0.004669135,0.01309504,0.1314845,0.03591816,0.4061679],"genre_scores_gemma":[0.03897726,0.03909159,0.4196033,0.006800137,0.0006153306,0.01019264,0.1739334,0.006749818,0.3040365],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.04197362,"threshold_uncertainty_score":0.1404157,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}